## Fri Nov 15 06:29:39 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin28/TLS_3_bin.13.fa -m mmseqs --itype genome -o TLS_3_bin.13 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/TLS_3_bin.13 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
TLS3_k127_1005944_2	1341181.FLJC2902T_22300	2.125e-121	402.0	COG0793@1|root,COG1680@1|root,COG0793@2|Bacteria,COG1680@2|Bacteria,4NGKK@976|Bacteroidetes,1HX0I@117743|Flavobacteriia,2NZ2C@237|Flavobacterium	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2
TLS3_k127_1005944_3	697282.Mettu_0542	2.887e-78	269.0	COG3861@1|root,COG3861@2|Bacteria,1RD6Y@1224|Proteobacteria,1S4FS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PRC
TLS3_k127_1005944_4	742766.HMPREF9455_01506	4.154e-29	118.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FP28@200643|Bacteroidia,22ZVD@171551|Porphyromonadaceae	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_1005944_1	1408473.JHXO01000009_gene3423	2.244e-158	518.0	COG4775@1|root,COG4775@2|Bacteria,4NR0H@976|Bacteroidetes,2FW6I@200643|Bacteroidia	976|Bacteroidetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
TLS3_k127_1005944_0	869213.JCM21142_104555	1.739e-201	668.0	COG2911@1|root,COG2911@2|Bacteria,4NSGX@976|Bacteroidetes	976|Bacteroidetes	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	AsmA,TamB
TLS3_k127_1016977_10	1177179.A11A3_10616	8.603e-07	53.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SABY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
TLS3_k127_1016977_5	1313301.AUGC01000001_gene1456	3.321e-99	344.0	COG0747@1|root,COG4288@1|root,COG0747@2|Bacteria,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes	976|Bacteroidetes	E	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
TLS3_k127_1016977_2	1223410.KN050846_gene1742	4.437e-139	449.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,1HYS3@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
TLS3_k127_1016977_4	357276.EL88_02930	4.254e-104	344.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,2FM1B@200643|Bacteroidia,4AM7E@815|Bacteroidaceae	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	deoD	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
TLS3_k127_1016977_7	1349785.BAUG01000011_gene847	1.551e-78	276.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,1HWU8@117743|Flavobacteriia	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
TLS3_k127_1016977_1	468059.AUHA01000003_gene1428	7.851e-152	502.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,1IP6H@117747|Sphingobacteriia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
TLS3_k127_1016977_8	272559.BF9343_0070	2.928e-42	160.0	COG0801@1|root,COG0801@2|Bacteria,4NGE8@976|Bacteroidetes,2FSKM@200643|Bacteroidia,4AR2H@815|Bacteroidaceae	976|Bacteroidetes	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
TLS3_k127_1016977_6	1250005.PHEL85_2613	4.054e-83	281.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,1HXJ3@117743|Flavobacteriia,3VVEH@52959|Polaribacter	976|Bacteroidetes	L	RadC-like JAB domain	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
TLS3_k127_1016977_9	742726.HMPREF9448_02527	2.388e-27	112.0	COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,2FTW4@200643|Bacteroidia,22YCU@171551|Porphyromonadaceae	976|Bacteroidetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
TLS3_k127_1016977_0	709991.Odosp_3246	4.444e-163	524.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,2FQTW@200643|Bacteroidia,22Y3A@171551|Porphyromonadaceae	976|Bacteroidetes	M	Mur ligase middle domain	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_1016977_3	1235803.C825_01825	4.838e-116	380.0	COG3622@1|root,COG3622@2|Bacteria,4NG0V@976|Bacteroidetes,2FSYZ@200643|Bacteroidia,22Z34@171551|Porphyromonadaceae	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
TLS3_k127_1042689_0	143224.JQMD01000002_gene248	5.814e-126	411.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,1I0Z8@117743|Flavobacteriia	976|Bacteroidetes	GK	ROK family	nagC	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,ROK
TLS3_k127_1042689_2	143224.JQMD01000002_gene249	1.02e-66	233.0	COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,1IAHR@117743|Flavobacteriia	976|Bacteroidetes	G	SIS domain	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
TLS3_k127_1042689_1	1121481.AUAS01000008_gene2991	4.171e-109	368.0	COG0546@1|root,COG2870@1|root,COG0546@2|Bacteria,COG2870@2|Bacteria,4NJ8F@976|Bacteroidetes,47MRA@768503|Cytophagia	976|Bacteroidetes	M	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase,PfkB
TLS3_k127_1043085_0	1168034.FH5T_12280	1.509e-208	659.0	COG0312@1|root,COG0312@2|Bacteria,4NG2Y@976|Bacteroidetes,2FN09@200643|Bacteroidia	976|Bacteroidetes	S	Tat pathway signal sequence domain protein	tldD1	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
TLS3_k127_106786_2	1121887.AUDK01000004_gene431	3.54e-28	123.0	COG2911@1|root,COG3210@1|root,COG3533@1|root,COG4625@1|root,COG4733@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3533@2|Bacteria,COG4625@2|Bacteria,COG4733@2|Bacteria,4PPKP@976|Bacteroidetes,1IKQ3@117743|Flavobacteriia,2P0T3@237|Flavobacterium	976|Bacteroidetes	U	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Laminin_G_3
TLS3_k127_106786_0	111780.Sta7437_0997	1.5e-48	183.0	2EZTP@1|root,33SY9@2|Bacteria,1GC0A@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_106786_1	1121904.ARBP01000006_gene4028	6.393e-32	142.0	295NE@1|root,2ZSZT@2|Bacteria,4NPQK@976|Bacteroidetes	976|Bacteroidetes	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
TLS3_k127_1070086_0	1239962.C943_03674	5.58e-201	657.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47KSH@768503|Cytophagia	976|Bacteroidetes	P	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,CarbopepD_reg_2,Plug
TLS3_k127_1070086_2	1168034.FH5T_14405	2.381e-61	218.0	COG1018@1|root,COG1018@2|Bacteria,4PCD8@976|Bacteroidetes,2FXQD@200643|Bacteroidia	976|Bacteroidetes	C	Oxidoreductase FAD-binding domain	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
TLS3_k127_1070086_1	234267.Acid_5499	1.008e-96	321.0	28KG3@1|root,2ZA20@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FixG_C,Peptidase_M6
TLS3_k127_1076592_1	997352.HMPREF9419_2289	4.612e-89	296.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,2FMED@200643|Bacteroidia	976|Bacteroidetes	O	ATPase histidine kinase DNA gyrase B HSP90 domain protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
TLS3_k127_1076592_3	468059.AUHA01000003_gene1826	3.712e-30	130.0	28P29@1|root,2ZBYD@2|Bacteria,4NMK6@976|Bacteroidetes,1IRUJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1076592_0	714943.Mucpa_4381	3.108e-149	482.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,1IQCC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS3_k127_1076592_2	385682.AFSL01000073_gene1398	8.93e-72	250.0	COG3279@1|root,COG3279@2|Bacteria,4NHUZ@976|Bacteroidetes,2G2TY@200643|Bacteroidia,3XJWG@558415|Marinilabiliaceae	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_1076592_4	397287.C807_02737	1.992e-15	79.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,27NRG@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
TLS3_k127_1088092_1	861299.J421_6020	1.626e-17	92.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	csxA	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575	3.2.1.165	ko:K15855	ko00520,ko01100,map00520,map01100	-	R01966	RC00049	ko00000,ko00001,ko01000	-	-	-	CBM_35,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
TLS3_k127_1088092_0	1121904.ARBP01000013_gene349	1.765e-137	448.0	COG4948@1|root,COG4948@2|Bacteria,4NKNN@976|Bacteroidetes,47JKW@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
TLS3_k127_1088151_11	385682.AFSL01000041_gene275	7.062e-12	65.0	COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,2FT2B@200643|Bacteroidia,3XIWD@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
TLS3_k127_1088151_2	1349822.NSB1T_06380	3.374e-101	334.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,2FM21@200643|Bacteroidia,22WZG@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
TLS3_k127_1088151_7	886379.AEWI01000078_gene1987	1.284e-60	218.0	COG2267@1|root,COG2267@2|Bacteria,4PKJZ@976|Bacteroidetes,2G0DQ@200643|Bacteroidia,3XIS2@558415|Marinilabiliaceae	976|Bacteroidetes	I	Putative serine esterase (DUF676)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_1088151_3	869213.JCM21142_385	1.523e-87	295.0	COG3298@1|root,COG3298@2|Bacteria,4NECH@976|Bacteroidetes,47Y3D@768503|Cytophagia	976|Bacteroidetes	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
TLS3_k127_1088151_4	1168289.AJKI01000031_gene963	3.553e-83	281.0	COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes,2FNW6@200643|Bacteroidia,3XKSD@558415|Marinilabiliaceae	976|Bacteroidetes	F	Phosphoribulokinase / Uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
TLS3_k127_1088151_1	1168034.FH5T_14145	1.144e-112	375.0	COG1482@1|root,COG1482@2|Bacteria,4NF9A@976|Bacteroidetes,2FN4I@200643|Bacteroidia	976|Bacteroidetes	G	mannose-6-phosphate isomerase	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
TLS3_k127_1088151_12	469606.FSCG_01190	1.365e-06	59.0	COG2849@1|root,COG2849@2|Bacteria,379WN@32066|Fusobacteria	32066|Fusobacteria	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_1088151_6	1168034.FH5T_14150	3.414e-70	243.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,2FM4M@200643|Bacteroidia	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
TLS3_k127_1088151_0	927658.AJUM01000037_gene2391	6.762e-122	398.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,3XJ9U@558415|Marinilabiliaceae	976|Bacteroidetes	EF	Phosphoribosyl synthetase-associated domain	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
TLS3_k127_1088151_9	927658.AJUM01000037_gene2392	4.778e-51	187.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,2FN3J@200643|Bacteroidia,3XIWN@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal L25p family	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
TLS3_k127_1088151_5	667015.Bacsa_1250	1.915e-76	260.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,2FN36@200643|Bacteroidia,4AKBS@815|Bacteroidaceae	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
TLS3_k127_1088151_10	484018.BACPLE_03321	3.568e-35	139.0	COG1188@1|root,COG1188@2|Bacteria,4NP8I@976|Bacteroidetes,2FRYM@200643|Bacteroidia,4AQNY@815|Bacteroidaceae	976|Bacteroidetes	J	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
TLS3_k127_1088151_8	1408473.JHXO01000007_gene966	1.283e-51	196.0	COG0204@1|root,COG0204@2|Bacteria,4NN7X@976|Bacteroidetes,2FUAF@200643|Bacteroidia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TLS3_k127_109066_7	1408473.JHXO01000002_gene3955	2.713e-68	247.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,2FN2J@200643|Bacteroidia	976|Bacteroidetes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_109066_6	153721.MYP_3667	5.355e-72	257.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,47MFI@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
TLS3_k127_109066_0	1433126.BN938_1128	0.0	1197.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,2FM3B@200643|Bacteroidia,22TZ1@171550|Rikenellaceae	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
TLS3_k127_109066_1	945713.IALB_2978	0.0	1182.0	COG2609@1|root,COG2609@2|Bacteria	2|Bacteria	C	pyruvate dehydrogenase (acetyl-transferring) activity	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
TLS3_k127_109066_4	880073.Calab_1318	7.326e-131	432.0	COG0508@1|root,COG0508@2|Bacteria,2NP69@2323|unclassified Bacteria	2|Bacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	aceF	GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_0111,iSSON_1240.SSON_0123,iYL1228.KPN_00119	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS3_k127_109066_3	472759.Nhal_2902	2.15e-155	503.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1WWGK@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
TLS3_k127_109066_2	1168034.FH5T_04775	1.048e-186	593.0	COG0436@1|root,COG0436@2|Bacteria,4NFWS@976|Bacteroidetes,2FMMU@200643|Bacteroidia	976|Bacteroidetes	H	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_109066_5	1123325.JHUV01000012_gene1021	5.911e-128	414.0	COG0253@1|root,COG0253@2|Bacteria,2G4B5@200783|Aquificae	200783|Aquificae	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
TLS3_k127_1099717_2	1408473.JHXO01000008_gene2658	2.089e-81	279.0	COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,2FU5J@200643|Bacteroidia	976|Bacteroidetes	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
TLS3_k127_1099717_1	1408473.JHXO01000008_gene2659	2.768e-105	346.0	COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,2FS5X@200643|Bacteroidia	976|Bacteroidetes	Q	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
TLS3_k127_1099717_0	927658.AJUM01000037_gene1865	1.374e-109	360.0	COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,2FSFN@200643|Bacteroidia	976|Bacteroidetes	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
TLS3_k127_1099717_4	1123009.AUID01000016_gene35	8.361e-37	142.0	COG1433@1|root,COG1433@2|Bacteria,1V74Q@1239|Firmicutes,24KWR@186801|Clostridia	186801|Clostridia	S	dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
TLS3_k127_1099717_3	504487.JCM19302_3542	2.06e-42	158.0	COG1342@1|root,COG1342@2|Bacteria,4NSEP@976|Bacteroidetes,1I9B7@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function  DUF134	-	-	-	-	-	-	-	-	-	-	-	-	DUF134,Nitro_FeMo-Co
TLS3_k127_111009_0	1185876.BN8_00257	6.724e-247	791.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47K68@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_111009_7	1122621.ATZA01000020_gene3970	4.954e-10	70.0	2E4RS@1|root,32ZKA@2|Bacteria,4PK7M@976|Bacteroidetes,1IU75@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_111009_3	616991.JPOO01000003_gene62	2.117e-127	416.0	COG2133@1|root,COG2133@2|Bacteria,4NG3Q@976|Bacteroidetes,1I7ZP@117743|Flavobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_111009_1	1121904.ARBP01000013_gene390	1.192e-196	623.0	COG3669@1|root,COG3669@2|Bacteria,4NEAP@976|Bacteroidetes,47JG2@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase C-terminal domain	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
TLS3_k127_111009_4	485918.Cpin_0142	8.931e-108	359.0	COG0457@1|root,COG0457@2|Bacteria,4NGID@976|Bacteroidetes,1IXMZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_111009_5	1168034.FH5T_20715	6.098e-66	231.0	2AU2S@1|root,31JP5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_111009_2	880073.Calab_2784	1.74e-167	543.0	COG1164@1|root,COG1164@2|Bacteria,2NQ8K@2323|unclassified Bacteria	2|Bacteria	E	Oligoendopeptidase f	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2,Peptidase_M3
TLS3_k127_111009_6	392499.Swit_1629	5.16e-36	142.0	2C85M@1|root,31482@2|Bacteria,1N2W2@1224|Proteobacteria,2UD7A@28211|Alphaproteobacteria,2K6FM@204457|Sphingomonadales	204457|Sphingomonadales	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
TLS3_k127_1125705_0	1123277.KB893172_gene574	1.638e-140	471.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1125705_1	709991.Odosp_2479	4.612e-125	405.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,2FRI1@200643|Bacteroidia,22XHE@171551|Porphyromonadaceae	976|Bacteroidetes	G	Fructose-1-6-bisphosphatase, N-terminal domain	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
TLS3_k127_1144726_0	765911.Thivi_2556	0.0	1355.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,1WXFY@135613|Chromatiales	135613|Chromatiales	G	Glycosyltransferase 36 associated	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
TLS3_k127_1159220_1	1453500.AT05_10220	1.643e-149	502.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_1159220_3	1121904.ARBP01000012_gene1316	5.661e-08	60.0	2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,47RV6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1159220_0	177437.HRM2_24930	2.006e-152	495.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2WJSW@28221|Deltaproteobacteria,2MHMC@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Fer4_9,PEP-utilizers,PK,PK_C
TLS3_k127_1159220_2	470145.BACCOP_00350	6.794e-59	208.0	COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,2FR57@200643|Bacteroidia,4AQMI@815|Bacteroidaceae	976|Bacteroidetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
TLS3_k127_1170462_4	483216.BACEGG_00329	2.626e-29	122.0	COG0845@1|root,COG4531@1|root,COG0845@2|Bacteria,COG4531@2|Bacteria,4NF6Y@976|Bacteroidetes,2FMZD@200643|Bacteroidia,4AMUN@815|Bacteroidaceae	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
TLS3_k127_1170462_0	1408473.JHXO01000013_gene600	0.0	1201.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,2FMH3@200643|Bacteroidia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
TLS3_k127_1170462_3	1408473.JHXO01000013_gene599	8.853e-40	162.0	COG1538@1|root,COG1538@2|Bacteria,4NIE8@976|Bacteroidetes,2FNS5@200643|Bacteroidia	976|Bacteroidetes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_1170462_5	1304874.JAFY01000007_gene1749	2.171e-11	68.0	2ENZG@1|root,33GKC@2|Bacteria,3TBSZ@508458|Synergistetes	508458|Synergistetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1170462_1	1123008.KB905693_gene1212	7.584e-174	554.0	COG0673@1|root,COG0673@2|Bacteria,4NDYI@976|Bacteroidetes,2G2S3@200643|Bacteroidia,22ZN4@171551|Porphyromonadaceae	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_1170462_2	1121890.AUDO01000011_gene398	3.305e-78	266.0	COG0668@1|root,COG0668@2|Bacteria,4NH7C@976|Bacteroidetes,1ICX5@117743|Flavobacteriia,2NVTM@237|Flavobacterium	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
TLS3_k127_1181175_0	1166018.FAES_5194	4.384e-200	640.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,47KH2@768503|Cytophagia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_1181175_2	1121887.AUDK01000014_gene2427	1.64e-108	357.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,1HXAY@117743|Flavobacteriia,2NTES@237|Flavobacterium	976|Bacteroidetes	C	CoB--CoM heterodisulfide reductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG
TLS3_k127_1181175_1	926549.KI421517_gene898	1.146e-117	392.0	COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,47JED@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
TLS3_k127_1181175_3	398720.MED217_01920	5.315e-99	334.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1HX9P@117743|Flavobacteriia,2XIJK@283735|Leeuwenhoekiella	976|Bacteroidetes	C	Electron transfer flavoprotein FAD-binding domain	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
TLS3_k127_1181175_5	153721.MYP_704	1.666e-78	269.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,47KZ2@768503|Cytophagia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
TLS3_k127_1181175_8	886379.AEWI01000047_gene3083	1.275e-67	241.0	COG0697@1|root,COG0697@2|Bacteria,4NNBQ@976|Bacteroidetes,2FMN9@200643|Bacteroidia,3XJBC@558415|Marinilabiliaceae	976|Bacteroidetes	EG	EamA-like transporter family	eamA	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_1181175_7	869213.JCM21142_104191	1.232e-70	252.0	COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,47KDM@768503|Cytophagia	976|Bacteroidetes	I	penicillin-binding protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_1181175_6	483216.BACEGG_00302	3.416e-74	256.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,2FM71@200643|Bacteroidia,4AKFU@815|Bacteroidaceae	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
TLS3_k127_1181175_4	1313301.AUGC01000004_gene2233	2.704e-96	323.0	COG0761@1|root,COG0761@2|Bacteria,4NDUX@976|Bacteroidetes	976|Bacteroidetes	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
TLS3_k127_1181175_9	744872.Spica_0826	2.301e-52	187.0	COG2768@1|root,COG2768@2|Bacteria,2J5VC@203691|Spirochaetes	203691|Spirochaetes	C	4Fe-4S ferredoxin, iron-sulfur binding	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4
TLS3_k127_1216218_0	929703.KE386491_gene2330	2.065e-88	298.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,47K1Q@768503|Cytophagia	976|Bacteroidetes	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_1216218_2	59374.Fisuc_2211	1.096e-65	230.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	dedA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
TLS3_k127_1216218_3	521674.Plim_3279	2.833e-41	154.0	COG0662@1|root,COG0662@2|Bacteria,2J39G@203682|Planctomycetes	203682|Planctomycetes	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1216218_1	1195236.CTER_3845	1.849e-80	278.0	arCOG12964@1|root,2Z7HP@2|Bacteria,1UZIT@1239|Firmicutes,24G0N@186801|Clostridia,3WJBI@541000|Ruminococcaceae	186801|Clostridia	S	Tocopherol cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Tocopherol_cycl
TLS3_k127_1221793_3	547042.BACCOPRO_00423	1.664e-127	412.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,2FMV2@200643|Bacteroidia,4AMM1@815|Bacteroidaceae	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
TLS3_k127_1221793_0	1121129.KB903359_gene2175	6.208e-189	598.0	COG0677@1|root,COG0677@2|Bacteria,4NDTW@976|Bacteroidetes,2FMXE@200643|Bacteroidia,22W6E@171551|Porphyromonadaceae	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TLS3_k127_1221793_2	313606.M23134_05641	6.761e-143	461.0	COG0673@1|root,COG0673@2|Bacteria,4PITU@976|Bacteroidetes,47KDG@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_1221793_4	709991.Odosp_0959	1.736e-92	306.0	COG0110@1|root,COG0110@2|Bacteria,4NENC@976|Bacteroidetes,2FP5Y@200643|Bacteroidia,22WU1@171551|Porphyromonadaceae	976|Bacteroidetes	S	Bacterial transferase hexapeptide repeat	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
TLS3_k127_1221793_1	926562.Oweho_1671	1.23e-143	464.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,1HXWJ@117743|Flavobacteriia,2PA9E@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM DegT DnrJ EryC1 StrS aminotransferase family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_1221793_5	709991.Odosp_3131	6.643e-17	82.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes,2G3F6@200643|Bacteroidia	976|Bacteroidetes	D	sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
TLS3_k127_1224918_1	694427.Palpr_0809	1.452e-130	430.0	COG0806@1|root,COG2239@1|root,COG0806@2|Bacteria,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,2FN1M@200643|Bacteroidia,22WIG@171551|Porphyromonadaceae	976|Bacteroidetes	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
TLS3_k127_1224918_0	1094508.Tsac_0520	7.435e-173	549.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,24ACU@186801|Clostridia,42F5H@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS07840	Nramp
TLS3_k127_1235090_5	385682.AFSL01000023_gene2167	1.564e-17	85.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,2FPJA@200643|Bacteroidia,3XK2I@558415|Marinilabiliaceae	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1235090_2	927658.AJUM01000037_gene2178	1.895e-210	670.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,2FM4X@200643|Bacteroidia,3XJ7N@558415|Marinilabiliaceae	976|Bacteroidetes	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
TLS3_k127_1235090_3	1168034.FH5T_11565	1.57e-125	419.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,2FNA1@200643|Bacteroidia	976|Bacteroidetes	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
TLS3_k127_1235090_4	746697.Aeqsu_2953	2.638e-50	186.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1I1CI@117743|Flavobacteriia	976|Bacteroidetes	S	phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
TLS3_k127_1235090_1	927658.AJUM01000037_gene2274	4.246e-229	716.0	COG2403@1|root,COG2403@2|Bacteria,4NHIW@976|Bacteroidetes,2FNNX@200643|Bacteroidia	976|Bacteroidetes	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1235090_0	1166018.FAES_0124	1.274e-291	906.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,47NZE@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Glyco_hydro_3,Glyco_hydro_3_C
TLS3_k127_1241199_9	688270.Celal_0681	0.0001392	50.0	2C03M@1|root,302N7@2|Bacteria,4PJQ0@976|Bacteroidetes,1IAN9@117743|Flavobacteriia,1FAMF@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1241199_2	143224.JQMD01000002_gene222	1.565e-93	348.0	COG1361@1|root,COG2304@1|root,COG3210@1|root,COG5183@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,COG3210@2|Bacteria,COG5183@2|Bacteria	2|Bacteria	A	chlorophyll binding	sca4	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	PRC,Phage_GPD,RHS_repeat,SLH
TLS3_k127_1241199_8	1121896.JMLU01000003_gene2115	5.988e-16	94.0	COG3656@1|root,COG3656@2|Bacteria,4PNNZ@976|Bacteroidetes,1I4RS@117743|Flavobacteriia,2P0TF@237|Flavobacterium	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
TLS3_k127_1241199_0	316067.Geob_1967	6.55e-169	581.0	COG1404@1|root,COG2911@1|root,COG3055@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,COG3055@2|Bacteria,1QXZF@1224|Proteobacteria	1224|Proteobacteria	M	family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3739,ESPR,Haemagg_act
TLS3_k127_1241199_1	1168034.FH5T_02880	2.097e-168	559.0	COG4206@1|root,COG4206@2|Bacteria,4PM79@976|Bacteroidetes	976|Bacteroidetes	H	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
TLS3_k127_1241199_4	1408473.JHXO01000008_gene2734	2.601e-49	186.0	COG3712@1|root,COG3712@2|Bacteria,4NH8I@976|Bacteroidetes,2FU8M@200643|Bacteroidia	976|Bacteroidetes	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
TLS3_k127_1241199_5	313606.M23134_01025	1.769e-41	157.0	COG1595@1|root,COG1595@2|Bacteria,4PIX2@976|Bacteroidetes,47W42@768503|Cytophagia	976|Bacteroidetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
TLS3_k127_1241199_6	1347342.BN863_2860	3.621e-41	156.0	COG0454@1|root,COG0456@2|Bacteria,4NQ7Z@976|Bacteroidetes,1I2SH@117743|Flavobacteriia	976|Bacteroidetes	K	(GNAT) family	-	-	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
TLS3_k127_1241199_7	1131269.AQVV01000010_gene2414	1.091e-31	127.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
TLS3_k127_1251367_1	999419.HMPREF1077_03144	2.168e-92	312.0	COG4299@1|root,COG4299@2|Bacteria,4NGKU@976|Bacteroidetes,2FQUY@200643|Bacteroidia,22ZR3@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
TLS3_k127_1251367_0	398720.MED217_09687	3.234e-260	821.0	COG3250@1|root,COG3250@2|Bacteria,4NF4T@976|Bacteroidetes,1HZ5Y@117743|Flavobacteriia	976|Bacteroidetes	G	beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Bgal_small_N,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
TLS3_k127_1258842_4	1348583.ATLH01000006_gene1075	1.286e-05	48.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1HY4Y@117743|Flavobacteriia,1F7Q7@104264|Cellulophaga	976|Bacteroidetes	M	SPTR Secreted protein containing N-terminal zinc-dependent carboxypeptidase related domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
TLS3_k127_1258842_0	927658.AJUM01000047_gene2951	6.93e-213	670.0	COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,2FMRS@200643|Bacteroidia,3XJP9@558415|Marinilabiliaceae	976|Bacteroidetes	E	Beta-eliminating lyase	-	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
TLS3_k127_1258842_2	1408473.JHXO01000006_gene1313	2.495e-157	503.0	COG0502@1|root,COG0502@2|Bacteria,4NI8V@976|Bacteroidetes,2FQC9@200643|Bacteroidia	976|Bacteroidetes	C	Iron-only hydrogenase maturation rSAM protein HydE	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
TLS3_k127_1258842_1	1433126.BN938_2213	1.364e-206	656.0	COG4690@1|root,COG4690@2|Bacteria,4NE03@976|Bacteroidetes,2FPSX@200643|Bacteroidia,22UN7@171550|Rikenellaceae	2|Bacteria	M	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
TLS3_k127_1258842_3	471854.Dfer_2159	5.231e-81	271.0	COG0708@1|root,COG0708@2|Bacteria,4NH0B@976|Bacteroidetes,47KKN@768503|Cytophagia	976|Bacteroidetes	L	Endonuclease/Exonuclease/phosphatase family	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
TLS3_k127_1291209_1	497964.CfE428DRAFT_5266	4.011e-130	425.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TLS3_k127_1291209_0	1288963.ADIS_4798	5.97e-178	561.0	COG4946@1|root,COG4946@2|Bacteria,4NJFC@976|Bacteroidetes,47JWA@768503|Cytophagia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_129300_7	1094980.Mpsy_2238	2.286e-39	158.0	COG1451@1|root,arCOG02625@2157|Archaea,2XZHC@28890|Euryarchaeota,2N9UB@224756|Methanomicrobia	224756|Methanomicrobia	S	WLM domain	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
TLS3_k127_129300_1	929562.Emtol_2630	6.186e-213	676.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,47JTA@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9,Polysacc_deac_1
TLS3_k127_129300_6	1408473.JHXO01000011_gene2985	6.311e-57	214.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,2FP07@200643|Bacteroidia	976|Bacteroidetes	S	Ser Thr phosphatase family protein	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
TLS3_k127_129300_9	1094508.Tsac_1115	1.938e-29	123.0	COG0454@1|root,COG1051@1|root,COG0456@2|Bacteria,COG1051@2|Bacteria,1V6EU@1239|Firmicutes,25BP0@186801|Clostridia	186801|Clostridia	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	FR47,NUDIX
TLS3_k127_129300_5	886379.AEWI01000010_gene627	1.157e-148	480.0	COG2208@1|root,COG2208@2|Bacteria,4NKGH@976|Bacteroidetes,2FNHT@200643|Bacteroidia,3XJHE@558415|Marinilabiliaceae	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
TLS3_k127_129300_3	385682.AFSL01000064_gene1705	1.056e-174	567.0	COG2221@1|root,COG4624@1|root,COG2221@2|Bacteria,COG4624@2|Bacteria,4NFXC@976|Bacteroidetes,2FP4U@200643|Bacteroidia,3XJD3@558415|Marinilabiliaceae	976|Bacteroidetes	C	Putative Fe-S cluster	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10
TLS3_k127_129300_10	469381.Dpep_0888	2.213e-13	73.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
TLS3_k127_129300_8	880073.Calab_1429	2.675e-37	145.0	COG1905@1|root,COG1905@2|Bacteria,2NPSB@2323|unclassified Bacteria	2|Bacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.12.1.4,1.6.5.3	ko:K00334,ko:K17999	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
TLS3_k127_129300_0	880073.Calab_1428	1.515e-220	701.0	COG1894@1|root,COG1894@2|Bacteria,2NNM1@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	hoxF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K05587,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
TLS3_k127_129300_4	880073.Calab_1427	4.686e-160	522.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,2NNXH@2323|unclassified Bacteria	2|Bacteria	C	Iron hydrogenase small subunit	-	-	1.12.1.3,1.17.1.9,1.6.5.3	ko:K00123,ko:K00336,ko:K18332	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_20,Fer4_6,Fer4_9,NADH-G_4Fe-4S_3,Pyr_redox_2
TLS3_k127_129300_2	880073.Calab_1426	4.689e-180	579.0	COG4191@1|root,COG4624@1|root,COG4191@2|Bacteria,COG4624@2|Bacteria,2NP4X@2323|unclassified Bacteria	2|Bacteria	C	Putative Fe-S cluster	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10,HAMP,HATPase_c,HTH_8,HisKA,PAS_9,Sigma54_activat
TLS3_k127_1299042_2	694427.Palpr_2963	9.041e-75	263.0	COG3291@1|root,COG5492@1|root,COG3291@2|Bacteria,COG5492@2|Bacteria,4PNJ8@976|Bacteroidetes,2G0UN@200643|Bacteroidia	976|Bacteroidetes	N	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1299042_0	869213.JCM21142_89	1.326e-110	373.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_1299042_1	927658.AJUM01000010_gene1354	2.937e-87	297.0	COG0642@1|root,COG2205@2|Bacteria,4NGZ0@976|Bacteroidetes,2FNI2@200643|Bacteroidia	976|Bacteroidetes	T	Response regulator receiver domain protein	pleD	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
TLS3_k127_1303283_3	391596.PBAL39_06781	2.482e-31	128.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1INUW@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_1303283_1	880073.Calab_2494	1.278e-101	338.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
TLS3_k127_1303283_2	1123008.KB905704_gene460	1.955e-75	261.0	COG3142@1|root,COG3142@2|Bacteria,4NINY@976|Bacteroidetes,2FN71@200643|Bacteroidia,22XRN@171551|Porphyromonadaceae	976|Bacteroidetes	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
TLS3_k127_1303283_0	709991.Odosp_2014	2.212e-214	679.0	COG4690@1|root,COG4690@2|Bacteria,4NE03@976|Bacteroidetes,2FPSX@200643|Bacteroidia,22WBK@171551|Porphyromonadaceae	976|Bacteroidetes	M	Dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
TLS3_k127_1322037_0	385682.AFSL01000062_gene1596	0.0	1040.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,2FMC9@200643|Bacteroidia,3XJ6E@558415|Marinilabiliaceae	976|Bacteroidetes	S	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
TLS3_k127_1367131_3	694427.Palpr_0805	2.475e-11	65.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
TLS3_k127_1367131_1	313598.MED152_12384	1.112e-99	340.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1HWXT@117743|Flavobacteriia,3VV44@52959|Polaribacter	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1367131_2	1408473.JHXO01000006_gene1346	3.069e-87	298.0	COG0697@1|root,COG0697@2|Bacteria,4NH9M@976|Bacteroidetes,2FPTW@200643|Bacteroidia	976|Bacteroidetes	EG	membrane	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_1367131_0	1122621.ATZA01000051_gene2851	4.594e-266	832.0	COG1506@1|root,COG1506@2|Bacteria,4NE2Q@976|Bacteroidetes,1IP3R@117747|Sphingobacteriia	976|Bacteroidetes	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
TLS3_k127_141999_0	1408473.JHXO01000002_gene3953	0.0	1057.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,2FM3B@200643|Bacteroidia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
TLS3_k127_141999_2	1408473.JHXO01000002_gene3952	4.529e-36	138.0	COG0347@1|root,COG0347@2|Bacteria,4NSBG@976|Bacteroidetes,2FT39@200643|Bacteroidia	976|Bacteroidetes	E	COG NOG19114 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_141999_1	886379.AEWI01000002_gene498	2.092e-235	740.0	COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,2FN1G@200643|Bacteroidia,3XINU@558415|Marinilabiliaceae	976|Bacteroidetes	J	Elongation factor G, domain IV	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
TLS3_k127_1426276_2	1380384.JADN01000007_gene1610	5.919e-84	282.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,4NERE@976|Bacteroidetes,1HXHW@117743|Flavobacteriia	976|Bacteroidetes	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
TLS3_k127_1426276_3	886379.AEWI01000001_gene1689	3.054e-72	254.0	COG0077@1|root,COG0077@2|Bacteria,4NEEK@976|Bacteroidetes,2FNHW@200643|Bacteroidia,3XJAD@558415|Marinilabiliaceae	976|Bacteroidetes	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
TLS3_k127_1426276_0	927658.AJUM01000044_gene601	3.696e-153	492.0	COG0436@1|root,COG0436@2|Bacteria,4NF2E@976|Bacteroidetes,2FN0N@200643|Bacteroidia,3XJ4N@558415|Marinilabiliaceae	976|Bacteroidetes	E	Aminotransferase class I and II	dapL	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_1426276_1	742817.HMPREF9449_02411	6.136e-86	292.0	COG0287@1|root,COG0287@2|Bacteria,4NEKF@976|Bacteroidetes,2FS5B@200643|Bacteroidia	976|Bacteroidetes	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
TLS3_k127_1444107_5	694427.Palpr_0810	2.516e-25	106.0	COG1914@1|root,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,2FUNV@200643|Bacteroidia,22YV7@171551|Porphyromonadaceae	976|Bacteroidetes	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
TLS3_k127_1444107_6	1410622.JNKY01000017_gene513	8.873e-10	70.0	COG1752@1|root,COG1752@2|Bacteria,1UBYN@1239|Firmicutes,247V3@186801|Clostridia,27MHG@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
TLS3_k127_1444107_3	344747.PM8797T_29628	2.231e-124	409.0	COG4409@1|root,COG4409@2|Bacteria,2J53Z@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TLS3_k127_1444107_4	1116369.KB890024_gene1987	5.641e-119	401.0	COG1473@1|root,COG1473@2|Bacteria,1MX6N@1224|Proteobacteria,2TRSE@28211|Alphaproteobacteria,43IKM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_1444107_1	1249997.JHZW01000002_gene1753	8.559e-142	458.0	COG0624@1|root,COG0624@2|Bacteria,4P1KC@976|Bacteroidetes,1I7KU@117743|Flavobacteriia,2PI7R@252356|Maribacter	976|Bacteroidetes	E	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
TLS3_k127_1444107_2	1380600.AUYN01000009_gene1055	3.22e-135	438.0	COG0451@1|root,COG0451@2|Bacteria,4NGEH@976|Bacteroidetes,1I80N@117743|Flavobacteriia	976|Bacteroidetes	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS3_k127_1444107_0	1392498.JQLH01000001_gene3355	1.763e-146	472.0	COG0329@1|root,COG0329@2|Bacteria,4NH72@976|Bacteroidetes,1HZCN@117743|Flavobacteriia,2PICI@252356|Maribacter	976|Bacteroidetes	EM	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
TLS3_k127_1444107_7	588581.Cpap_3421	0.0002427	46.0	COG0204@1|root,COG0204@2|Bacteria,1U51E@1239|Firmicutes	1239|Firmicutes	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TLS3_k127_1454237_8	1168034.FH5T_03190	1.141e-11	65.0	COG1629@1|root,COG4771@2|Bacteria,4NEHN@976|Bacteroidetes,2FNEZ@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_1454237_4	1408473.JHXO01000011_gene3221	2.57e-53	195.0	COG3201@1|root,COG3201@2|Bacteria,4NFJI@976|Bacteroidetes,2FRYG@200643|Bacteroidia	976|Bacteroidetes	H	nicotinamide mononucleotide transporter	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
TLS3_k127_1454237_3	1123008.KB905692_gene247	2.521e-62	220.0	COG1564@1|root,COG1564@2|Bacteria,4NPR1@976|Bacteroidetes,2FP1N@200643|Bacteroidia,22XY5@171551|Porphyromonadaceae	976|Bacteroidetes	H	Thiamin pyrophosphokinase, catalytic domain	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_catalytic
TLS3_k127_1454237_2	1408473.JHXO01000001_gene2213	1.81e-66	238.0	COG2197@1|root,COG2197@2|Bacteria,4NP7F@976|Bacteroidetes	976|Bacteroidetes	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
TLS3_k127_1454237_5	1408473.JHXO01000001_gene2211	5.514e-50	188.0	COG5523@1|root,COG5523@2|Bacteria,4NM5R@976|Bacteroidetes	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
TLS3_k127_1454237_1	1408473.JHXO01000006_gene1273	1.608e-270	852.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,2FNIM@200643|Bacteroidia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
TLS3_k127_1454237_0	694427.Palpr_0751	0.0	1053.0	COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes,2FMF9@200643|Bacteroidia,22W4V@171551|Porphyromonadaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
TLS3_k127_1454237_6	1499967.BAYZ01000111_gene2953	5.489e-46	168.0	COG3254@1|root,COG3254@2|Bacteria,2NRFN@2323|unclassified Bacteria	2|Bacteria	S	L-rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
TLS3_k127_1454237_7	1168034.FH5T_12670	6.478e-46	183.0	COG3291@1|root,COG3291@2|Bacteria,4NU2U@976|Bacteroidetes,2FNZM@200643|Bacteroidia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_1469919_1	1408473.JHXO01000001_gene2352	4.451e-38	145.0	COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,2FU2A@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
TLS3_k127_1469919_0	1408473.JHXO01000001_gene2180	2.015e-106	348.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,2FNGN@200643|Bacteroidia	976|Bacteroidetes	GK	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
TLS3_k127_1487832_1	1349785.BAUG01000034_gene1913	2.902e-10	61.0	COG0389@1|root,COG0389@2|Bacteria,4NF1Y@976|Bacteroidetes,1HXHJ@117743|Flavobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
TLS3_k127_1487832_0	1408473.JHXO01000004_gene92	6.063e-152	507.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,2FPNU@200643|Bacteroidia	976|Bacteroidetes	L	SNF2 family N-terminal domain	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N
TLS3_k127_1494150_0	1185876.BN8_03554	1.042e-244	775.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,47KZ5@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycosyl Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
TLS3_k127_149428_0	1121887.AUDK01000023_gene3477	4.329e-217	681.0	COG0823@1|root,COG0823@2|Bacteria,4NFQ0@976|Bacteroidetes,1I7I9@117743|Flavobacteriia,2NSYV@237|Flavobacterium	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	PD40,Pectate_lyase22
TLS3_k127_149428_1	1168034.FH5T_01640	2.799e-117	390.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TLS3_k127_149428_2	1121104.AQXH01000002_gene616	1.755e-36	145.0	COG1595@1|root,COG1595@2|Bacteria,4NMYQ@976|Bacteroidetes,1ITN5@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM RNA polymerase sigma factor 70, region 4 type 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_149428_3	926549.KI421517_gene2974	2.781e-29	127.0	COG1413@1|root,COG1413@2|Bacteria,4NIBA@976|Bacteroidetes,47M5K@768503|Cytophagia	976|Bacteroidetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,zf-HC2
TLS3_k127_149428_4	1185876.BN8_00879	1.939e-28	123.0	COG3595@1|root,COG3595@2|Bacteria,4NGRU@976|Bacteroidetes,47MSM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
TLS3_k127_149879_3	913865.DOT_2962	4.67e-82	276.0	COG0204@1|root,COG0204@2|Bacteria,1U51E@1239|Firmicutes	1239|Firmicutes	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TLS3_k127_149879_0	1408473.JHXO01000012_gene383	1.263e-247	774.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,2FNXT@200643|Bacteroidia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
TLS3_k127_149879_1	700598.Niako_3638	1.657e-210	664.0	COG2160@1|root,COG2160@2|Bacteria,4NHGG@976|Bacteroidetes,1IPX0@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
TLS3_k127_149879_2	698758.AXY_21520	1.924e-91	307.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,4H9W0@91061|Bacilli	91061|Bacilli	G	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source	araD	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
TLS3_k127_149879_4	761193.Runsl_3382	4.471e-26	110.0	COG1069@1|root,COG1069@2|Bacteria,4NEFQ@976|Bacteroidetes,47KBR@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
TLS3_k127_1500217_0	865937.Gilli_2019	4.814e-208	659.0	COG2866@1|root,COG2866@2|Bacteria,4NH4I@976|Bacteroidetes,1I15Z@117743|Flavobacteriia	976|Bacteroidetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
TLS3_k127_151849_1	376686.Fjoh_2575	9.593e-75	261.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1HX7S@117743|Flavobacteriia,2NSD9@237|Flavobacterium	976|Bacteroidetes	E	homoserine dehydrogenase	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
TLS3_k127_151849_0	1123008.KB905693_gene1354	7.006e-236	738.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,2FNB6@200643|Bacteroidia,22WY5@171551|Porphyromonadaceae	976|Bacteroidetes	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
TLS3_k127_1533401_1	641107.CDLVIII_0771	2.763e-21	97.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,36F3K@31979|Clostridiaceae	186801|Clostridia	G	Carbohydrate kinase, FGGY	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
TLS3_k127_1533401_0	1123277.KB893174_gene6077	8.38e-321	1015.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47Y7Y@768503|Cytophagia	976|Bacteroidetes	H	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_153851_9	1166018.FAES_0717	8.835e-05	48.0	COG2378@1|root,COG2378@2|Bacteria,4NI15@976|Bacteroidetes,47N9F@768503|Cytophagia	976|Bacteroidetes	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
TLS3_k127_153851_7	517418.Ctha_2614	1.109e-30	129.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
TLS3_k127_153851_1	1123057.P872_20295	4.862e-93	312.0	COG0730@1|root,COG0730@2|Bacteria,4NKE8@976|Bacteroidetes,47X4Q@768503|Cytophagia	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_153851_3	1444711.CCJF01000004_gene2151	2.137e-67	236.0	COG0400@1|root,COG0400@2|Bacteria,2JGZY@204428|Chlamydiae	204428|Chlamydiae	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
TLS3_k127_153851_0	1444711.CCJF01000004_gene2152	6.432e-131	425.0	COG0346@1|root,COG0346@2|Bacteria,2JGVE@204428|Chlamydiae	204428|Chlamydiae	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_153851_5	1121285.AUFK01000009_gene846	2.906e-39	151.0	COG1917@1|root,COG1917@2|Bacteria,4NQ6V@976|Bacteroidetes,1I95T@117743|Flavobacteriia,3ZSBW@59732|Chryseobacterium	976|Bacteroidetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_153851_4	1123248.KB893318_gene4096	4.089e-45	168.0	COG2259@1|root,COG2259@2|Bacteria,4NNA7@976|Bacteroidetes,1IYPI@117747|Sphingobacteriia	976|Bacteroidetes	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
TLS3_k127_153851_2	1168034.FH5T_04790	7.477e-91	307.0	COG2126@1|root,COG2126@2|Bacteria,4NEX1@976|Bacteroidetes,2FMAY@200643|Bacteroidia	976|Bacteroidetes	J	Transporter, cation channel family protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
TLS3_k127_153851_6	1168034.FH5T_04435	7.821e-37	141.0	COG0702@1|root,COG0702@2|Bacteria,4PKTF@976|Bacteroidetes,2G0WC@200643|Bacteroidia	976|Bacteroidetes	GM	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_1554548_1	1223410.KN050846_gene286	3.189e-272	858.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_1554548_0	694427.Palpr_0579	0.0	1510.0	COG3250@1|root,COG3250@2|Bacteria,4NKZX@976|Bacteroidetes,2FNTC@200643|Bacteroidia,22ZRF@171551|Porphyromonadaceae	976|Bacteroidetes	G	Concanavalin A-like lectin/glucanases superfamily	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3
TLS3_k127_1554548_2	1296416.JACB01000029_gene4151	3.701e-85	291.0	COG1396@1|root,COG1396@2|Bacteria,4NN87@976|Bacteroidetes,1I1CB@117743|Flavobacteriia,2YI3Z@290174|Aquimarina	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
TLS3_k127_1582299_0	1123057.P872_02175	2.034e-111	367.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,47KMG@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_1582299_4	402612.FP2413	1.222e-16	91.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NU73@237|Flavobacterium	976|Bacteroidetes	O	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CUB,Cleaved_Adhesin,P_proprotein,SBBP,fn3
TLS3_k127_1582299_3	927658.AJUM01000037_gene2300	1.119e-42	168.0	COG3064@1|root,COG3064@2|Bacteria,4P2YP@976|Bacteroidetes,2G32U@200643|Bacteroidia,3XJ0Z@558415|Marinilabiliaceae	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_1582299_2	869213.JCM21142_41900	2.239e-85	300.0	COG0823@1|root,COG2885@1|root,COG3291@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,COG3291@2|Bacteria,4NE6G@976|Bacteroidetes,47K1N@768503|Cytophagia	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,PKD
TLS3_k127_1582299_1	886379.AEWI01000005_gene929	1.857e-105	350.0	COG3291@1|root,COG3291@2|Bacteria,4NHJJ@976|Bacteroidetes,2G20Y@200643|Bacteroidia,3XJ8K@558415|Marinilabiliaceae	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_158445_5	742817.HMPREF9449_00812	9.465e-34	135.0	COG1752@1|root,COG1752@2|Bacteria,4NERH@976|Bacteroidetes,2FNX7@200643|Bacteroidia,22XKQ@171551|Porphyromonadaceae	976|Bacteroidetes	S	Phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
TLS3_k127_158445_0	1121129.KB903359_gene1915	4.441e-126	408.0	COG0648@1|root,COG0648@2|Bacteria,4NJDP@976|Bacteroidetes,2FPM6@200643|Bacteroidia,22WPU@171551|Porphyromonadaceae	976|Bacteroidetes	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
TLS3_k127_158445_2	1408473.JHXO01000001_gene2222	2.432e-55	205.0	COG1196@1|root,COG1196@2|Bacteria,4PMJ4@976|Bacteroidetes,2G0CX@200643|Bacteroidia	976|Bacteroidetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_158445_1	435590.BVU_0018	2.827e-111	370.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,2FPFC@200643|Bacteroidia,4AKQX@815|Bacteroidaceae	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
TLS3_k127_158445_6	709991.Odosp_2637	1.012e-06	55.0	COG5652@1|root,COG5652@2|Bacteria,4PA3X@976|Bacteroidetes,2FVHF@200643|Bacteroidia	976|Bacteroidetes	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
TLS3_k127_158445_4	869213.JCM21142_420	1.996e-34	136.0	COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,47RNG@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
TLS3_k127_158445_3	709991.Odosp_2846	6.94e-53	190.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,2FT1X@200643|Bacteroidia,22XV0@171551|Porphyromonadaceae	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
TLS3_k127_1603727_3	1293054.HSACCH_00722	5.507e-40	153.0	COG1656@1|root,COG1656@2|Bacteria,1V62E@1239|Firmicutes,24IZW@186801|Clostridia	186801|Clostridia	H	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
TLS3_k127_1603727_2	1121904.ARBP01000004_gene856	4.409e-109	366.0	COG1454@1|root,COG1454@2|Bacteria,4NE5Y@976|Bacteroidetes	976|Bacteroidetes	C	Dehydrogenase	-	-	1.1.1.61	ko:K18120,ko:K19954	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R01644	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
TLS3_k127_1603727_4	1173022.Cri9333_2605	1.626e-31	125.0	COG1359@1|root,COG1359@2|Bacteria,1G8H0@1117|Cyanobacteria,1HC7H@1150|Oscillatoriales	1117|Cyanobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
TLS3_k127_1603727_1	1121904.ARBP01000003_gene6582	3.206e-122	401.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_1603727_0	1123248.KB893381_gene968	3.413e-222	697.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,1IRDK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_1603727_5	1492738.FEM21_07990	9.563e-24	104.0	COG0745@1|root,COG0745@2|Bacteria,4NQNT@976|Bacteroidetes,1I3AQ@117743|Flavobacteriia,2NWVA@237|Flavobacterium	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_1603727_6	1168034.FH5T_09845	7.36e-22	108.0	COG0457@1|root,COG0457@2|Bacteria,4NGMH@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
TLS3_k127_1614682_3	471852.Tcur_4562	2.838e-48	181.0	COG2128@1|root,COG2128@2|Bacteria,2IJCK@201174|Actinobacteria,4EM1P@85012|Streptosporangiales	201174|Actinobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
TLS3_k127_1614682_1	536227.CcarbDRAFT_0611	9.484e-112	372.0	COG0596@1|root,COG0596@2|Bacteria,1UHTA@1239|Firmicutes,25EE8@186801|Clostridia,36UMU@31979|Clostridiaceae	186801|Clostridia	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
TLS3_k127_1614682_0	1189612.A33Q_1470	2.315e-115	381.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,47JKN@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_1614682_4	742817.HMPREF9449_00057	1.211e-11	73.0	2924H@1|root,2ZPPH@2|Bacteria,4NNST@976|Bacteroidetes,2FR7C@200643|Bacteroidia,22YFV@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4251)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4251
TLS3_k127_1614682_5	269797.Mbar_A2893	2.867e-06	59.0	COG0457@1|root,arCOG03038@2157|Archaea,2XUNW@28890|Euryarchaeota	28890|Euryarchaeota	O	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
TLS3_k127_1614682_2	1408473.JHXO01000014_gene4069	2.697e-105	349.0	COG0657@1|root,COG2382@1|root,COG0657@2|Bacteria,COG2382@2|Bacteria,4NH62@976|Bacteroidetes,2FQH7@200643|Bacteroidia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
TLS3_k127_1632353_1	1122605.KB893626_gene2609	1.59e-83	287.0	COG1335@1|root,COG1335@2|Bacteria,4P3A5@976|Bacteroidetes	976|Bacteroidetes	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
TLS3_k127_1632353_0	1122605.KB893647_gene368	3.948e-183	584.0	COG0673@1|root,COG0673@2|Bacteria,4P16C@976|Bacteroidetes,1IWQM@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_1651073_0	385682.AFSL01000019_gene2217	1.509e-234	741.0	COG0497@1|root,COG0497@2|Bacteria,4PMJC@976|Bacteroidetes,2G0DC@200643|Bacteroidia,3XJNG@558415|Marinilabiliaceae	976|Bacteroidetes	L	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
TLS3_k127_1653974_5	1124780.ANNU01000049_gene2205	0.0003267	46.0	2AAU0@1|root,3106Q@2|Bacteria,4NNSV@976|Bacteroidetes,47Q0I@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1653974_0	886379.AEWI01000007_gene843	1.46e-255	821.0	COG1131@1|root,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,2FRF1@200643|Bacteroidia,3XIKU@558415|Marinilabiliaceae	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran
TLS3_k127_1653974_1	1408473.JHXO01000001_gene2236	5.837e-104	367.0	COG5616@1|root,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1653974_6	746697.Aeqsu_2760	0.0003438	54.0	2BTQM@1|root,32NXS@2|Bacteria,4PFK3@976|Bacteroidetes,1I7AQ@117743|Flavobacteriia	976|Bacteroidetes	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
TLS3_k127_1653974_2	1408473.JHXO01000008_gene2665	4.138e-80	273.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,2FNU2@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the ompA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
TLS3_k127_1653974_4	700598.Niako_0121	1.019e-44	171.0	COG3637@1|root,COG3637@2|Bacteria,4NWBY@976|Bacteroidetes,1J0D4@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1653974_3	1408473.JHXO01000009_gene3294	1.281e-64	230.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,2FN9Q@200643|Bacteroidia	976|Bacteroidetes	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1658362_1	385682.AFSL01000061_gene1753	1.926e-153	495.0	COG0612@1|root,COG0612@2|Bacteria,4NEE4@976|Bacteroidetes,2FN50@200643|Bacteroidia,3XIR5@558415|Marinilabiliaceae	976|Bacteroidetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_1658362_0	1396418.BATQ01000011_gene4506	3.781e-164	528.0	COG1680@1|root,COG5297@1|root,COG1680@2|Bacteria,COG5297@2|Bacteria,46TK0@74201|Verrucomicrobia,2IVMJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1593
TLS3_k127_1663922_2	485918.Cpin_6691	2.864e-67	233.0	COG0262@1|root,COG0262@2|Bacteria,4NJIQ@976|Bacteroidetes,1IWPD@117747|Sphingobacteriia	976|Bacteroidetes	H	bifunctional deaminase-reductase domain protein	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
TLS3_k127_1663922_0	1408473.JHXO01000005_gene1510	4.761e-211	676.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,2FNDE@200643|Bacteroidia	976|Bacteroidetes	CO	cytochrome c biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
TLS3_k127_1663922_1	1168289.AJKI01000011_gene483	5.978e-151	485.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,2FMXV@200643|Bacteroidia,3XJFA@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribonuclease E/G family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
TLS3_k127_1672760_3	700598.Niako_6329	4.016e-80	270.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,1IRDU@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TLS3_k127_1672760_1	1123248.KB893314_gene3562	7.908e-152	491.0	COG1030@1|root,COG1030@2|Bacteria,4NGGV@976|Bacteroidetes,1IPJY@117747|Sphingobacteriia	976|Bacteroidetes	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
TLS3_k127_1672760_2	385682.AFSL01000039_gene142	3.569e-140	457.0	2CA5R@1|root,2Z81H@2|Bacteria,4NGSF@976|Bacteroidetes,2FXDN@200643|Bacteroidia,3XKS0@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
TLS3_k127_1672760_5	1158294.JOMI01000003_gene2309	5.689e-34	135.0	COG1733@1|root,COG1733@2|Bacteria,4PMBV@976|Bacteroidetes	976|Bacteroidetes	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
TLS3_k127_1672760_4	865937.Gilli_0866	4.577e-51	189.0	COG3127@1|root,COG3127@2|Bacteria,4NN8S@976|Bacteroidetes,1I2BI@117743|Flavobacteriia	976|Bacteroidetes	Q	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1672760_0	1123393.KB891326_gene42	0.0	2290.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria,1KSRI@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
TLS3_k127_170968_2	927658.AJUM01000037_gene2070	6.124e-41	157.0	COG0168@1|root,COG0168@2|Bacteria,4NGMF@976|Bacteroidetes,2FNQZ@200643|Bacteroidia,3XIYR@558415|Marinilabiliaceae	976|Bacteroidetes	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
TLS3_k127_170968_0	1185876.BN8_02846	1.34e-166	532.0	COG2382@1|root,COG2382@2|Bacteria,4NF50@976|Bacteroidetes,47MEB@768503|Cytophagia	976|Bacteroidetes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
TLS3_k127_170968_1	1166018.FAES_1704	3.681e-134	438.0	COG2133@1|root,COG2133@2|Bacteria,4NEZC@976|Bacteroidetes,47KSC@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,GSDH
TLS3_k127_170968_3	1123277.KB893216_gene4864	1.096e-38	164.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,47V2C@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
TLS3_k127_1711395_2	1499967.BAYZ01000009_gene5389	1.825e-154	499.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
TLS3_k127_1711395_1	1380600.AUYN01000009_gene1448	2.452e-198	627.0	COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,1HY74@117743|Flavobacteriia	976|Bacteroidetes	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	xylE	-	-	ko:K02100,ko:K03444,ko:K08138	-	-	-	-	ko00000,ko02000	2.A.1.1,2.A.1.1.2,2.A.1.1.3	-	-	Sugar_tr
TLS3_k127_1711395_0	1123248.KB893317_gene4349	0.0	1019.0	COG3250@1|root,COG3250@2|Bacteria,4NEP8@976|Bacteroidetes,1IR90@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
TLS3_k127_1711395_3	1121904.ARBP01000008_gene3256	2.34e-103	346.0	COG0667@1|root,COG0667@2|Bacteria,4PPAM@976|Bacteroidetes	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_1711395_4	1286632.P278_03700	9.704e-53	193.0	COG2010@1|root,COG2010@2|Bacteria,4NQXA@976|Bacteroidetes,1I33C@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TLS3_k127_1711395_6	1123277.KB893210_gene2865	1.874e-10	69.0	COG3047@1|root,COG3047@2|Bacteria,4PA4G@976|Bacteroidetes,47SQP@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_1711395_7	411901.BACCAC_03171	3.975e-07	53.0	2A76E@1|root,30W2E@2|Bacteria,4P9FC@976|Bacteroidetes,2FZNB@200643|Bacteroidia,4AUSK@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1711395_5	1218103.CIN01S_12_02800	4.145e-19	97.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,1HYTK@117743|Flavobacteriia,3ZNXS@59732|Chryseobacterium	976|Bacteroidetes	M	RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1712618_6	755732.Fluta_1591	1.97e-24	106.0	COG0438@1|root,COG0438@2|Bacteria,4NH7K@976|Bacteroidetes,1I0D7@117743|Flavobacteriia,2PAGP@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_1712618_2	351160.RCIX701	6.166e-48	179.0	COG4430@1|root,arCOG10241@2157|Archaea,2XUJA@28890|Euryarchaeota	28890|Euryarchaeota	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
TLS3_k127_1712618_1	709991.Odosp_3524	1.408e-98	333.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,2FN91@200643|Bacteroidia,22X7N@171551|Porphyromonadaceae	976|Bacteroidetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
TLS3_k127_1712618_0	886379.AEWI01000013_gene2086	4.464e-102	342.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,2FMVX@200643|Bacteroidia,3XJQ3@558415|Marinilabiliaceae	976|Bacteroidetes	S	YceG-like family	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
TLS3_k127_1712618_4	468059.AUHA01000006_gene2907	9.444e-33	131.0	COG0730@1|root,COG0730@2|Bacteria,4NTZ8@976|Bacteroidetes	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_1712618_5	1121904.ARBP01000002_gene6734	1.691e-28	123.0	COG3637@1|root,COG3637@2|Bacteria,4PJMQ@976|Bacteroidetes,47QZZ@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_1712618_3	1168289.AJKI01000011_gene526	1.765e-35	137.0	COG1225@1|root,COG1225@2|Bacteria,4PMJJ@976|Bacteroidetes,2G0DM@200643|Bacteroidia,3XKQZ@558415|Marinilabiliaceae	976|Bacteroidetes	O	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TLS3_k127_1712661_2	1408473.JHXO01000001_gene2145	2.388e-16	85.0	2CK1R@1|root,32V4M@2|Bacteria,4NTYZ@976|Bacteroidetes,2FU5M@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1712661_0	1191523.MROS_1186	1.101e-176	566.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
TLS3_k127_1712661_1	439235.Dalk_0712	4.594e-72	248.0	COG0560@1|root,COG0560@2|Bacteria,1MZPG@1224|Proteobacteria,42Q82@68525|delta/epsilon subdivisions,2WMBU@28221|Deltaproteobacteria,2MI8W@213118|Desulfobacterales	28221|Deltaproteobacteria	E	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	-	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD
TLS3_k127_1721477_3	927658.AJUM01000024_gene2598	2.584e-102	334.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,2FNKW@200643|Bacteroidia,3XJM7@558415|Marinilabiliaceae	976|Bacteroidetes	J	PCRF	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TLS3_k127_1721477_2	385682.AFSL01000062_gene1601	2.433e-113	371.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,2FPJM@200643|Bacteroidia,3XJVW@558415|Marinilabiliaceae	976|Bacteroidetes	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
TLS3_k127_1721477_1	1408473.JHXO01000006_gene1045	2.39e-123	409.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,2FPMP@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
TLS3_k127_1721477_4	742817.HMPREF9449_00249	6.379e-35	136.0	COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,2FTTZ@200643|Bacteroidia,22YD7@171551|Porphyromonadaceae	976|Bacteroidetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
TLS3_k127_1721477_0	742725.HMPREF9450_00136	1.533e-213	671.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,22U7B@171550|Rikenellaceae	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
TLS3_k127_1729861_3	1168034.FH5T_09280	7.992e-82	275.0	COG2391@1|root,COG2391@2|Bacteria,4NGS1@976|Bacteroidetes	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
TLS3_k127_1729861_2	1168034.FH5T_09275	1.763e-88	299.0	COG2391@1|root,COG2391@2|Bacteria,4NMK0@976|Bacteroidetes	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
TLS3_k127_1729861_1	1168034.FH5T_09260	1.525e-114	378.0	COG2897@1|root,COG2897@2|Bacteria,4NKP3@976|Bacteroidetes	976|Bacteroidetes	M	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS3_k127_1729861_0	1168034.FH5T_09255	6.153e-118	390.0	28IWX@1|root,2Z8V0@2|Bacteria,4PPT4@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1729861_4	1168034.FH5T_17165	1.237e-61	218.0	COG4843@1|root,COG4843@2|Bacteria,4NRH5@976|Bacteroidetes,2FSZ5@200643|Bacteroidia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
TLS3_k127_1735446_3	489825.LYNGBM3L_09080	1.028e-08	58.0	COG0515@1|root,COG0642@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Hpt,Pkinase,Response_reg
TLS3_k127_1735446_2	1121912.AUHD01000017_gene3524	3.214e-63	228.0	COG0438@1|root,COG0438@2|Bacteria,4NHPJ@976|Bacteroidetes,1HZFJ@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_1735446_1	1227739.Hsw_1662	6.77e-97	332.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,47P7K@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
TLS3_k127_1735446_0	1168034.FH5T_09120	8.989e-164	518.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,2FMM2@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
TLS3_k127_1742841_0	1047013.AQSP01000100_gene584	1.39e-94	332.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1751291_8	153721.MYP_4587	5.726e-38	147.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,47PXV@768503|Cytophagia	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
TLS3_k127_1751291_10	1349822.NSB1T_05520	5.302e-33	132.0	COG2137@1|root,COG2137@2|Bacteria,4NSAS@976|Bacteroidetes,2FS4X@200643|Bacteroidia,22YE0@171551|Porphyromonadaceae	976|Bacteroidetes	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
TLS3_k127_1751291_14	63737.Npun_R0510	0.0009159	48.0	2E7Q2@1|root,3325J@2|Bacteria,1G91H@1117|Cyanobacteria,1HSG9@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
TLS3_k127_1751291_13	553177.CAPSP0001_0506	6.036e-06	55.0	2ACM8@1|root,3127P@2|Bacteria,4PH37@976|Bacteroidetes,1IHTQ@117743|Flavobacteriia,1ETAA@1016|Capnocytophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1751291_11	1121007.AUML01000001_gene1332	5.763e-30	126.0	COG0526@1|root,COG0526@2|Bacteria,4NQI3@976|Bacteroidetes,1I2TH@117743|Flavobacteriia,2YHR4@290174|Aquimarina	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_9
TLS3_k127_1751291_0	385682.AFSL01000008_gene2540	0.0	1162.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,2FNWM@200643|Bacteroidia,3XJE9@558415|Marinilabiliaceae	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
TLS3_k127_1751291_2	1168289.AJKI01000002_gene2389	8.538e-196	629.0	COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,3XJ4V@558415|Marinilabiliaceae	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
TLS3_k127_1751291_3	886379.AEWI01000005_gene912	7.383e-146	469.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,2FMZK@200643|Bacteroidia,3XJKW@558415|Marinilabiliaceae	976|Bacteroidetes	J	PCRF	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TLS3_k127_1751291_4	700598.Niako_6518	1.67e-73	253.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,1IP7Z@117747|Sphingobacteriia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
TLS3_k127_1751291_1	886379.AEWI01000037_gene3002	9.06e-247	781.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,2FMI1@200643|Bacteroidia,3XJ9S@558415|Marinilabiliaceae	976|Bacteroidetes	E	Peptidase S46	dpp7	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009987,GO:0016020,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033218,GO:0034641,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
TLS3_k127_1751291_6	385682.AFSL01000033_gene2893	7.547e-60	214.0	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,2FNCS@200643|Bacteroidia,3XJF1@558415|Marinilabiliaceae	976|Bacteroidetes	U	MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
TLS3_k127_1751291_5	1408473.JHXO01000001_gene2301	2.697e-64	224.0	COG0328@1|root,COG0328@2|Bacteria,4NNQX@976|Bacteroidetes,2FSJX@200643|Bacteroidia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
TLS3_k127_1751291_12	1313301.AUGC01000004_gene2306	4.77e-20	95.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
TLS3_k127_1751291_7	203275.BFO_0293	3.772e-59	209.0	COG3760@1|root,COG3760@2|Bacteria,4NNW9@976|Bacteroidetes,2FSY6@200643|Bacteroidia,22Y37@171551|Porphyromonadaceae	976|Bacteroidetes	S	Aminoacyl-tRNA editing domain	proX	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
TLS3_k127_1751291_9	1408473.JHXO01000008_gene2886	4.959e-33	132.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,2FS4M@200643|Bacteroidia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_1755652_2	929556.Solca_4246	3.288e-77	276.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
TLS3_k127_1755652_0	886379.AEWI01000013_gene2046	1.429e-96	321.0	COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,2G25S@200643|Bacteroidia,3XJZT@558415|Marinilabiliaceae	976|Bacteroidetes	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
TLS3_k127_1755652_1	679937.Bcop_0763	3.149e-84	287.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,2FP6C@200643|Bacteroidia,4AKCR@815|Bacteroidaceae	976|Bacteroidetes	C	COG0169 Shikimate 5-dehydrogenase	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
TLS3_k127_1755652_3	1347393.HG726020_gene1557	4.526e-08	54.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,2FP2H@200643|Bacteroidia,4AK8G@815|Bacteroidaceae	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
TLS3_k127_1787633_5	1121875.KB907547_gene3151	7.366e-20	93.0	2CWXQ@1|root,32T0K@2|Bacteria,4NTPX@976|Bacteroidetes,1I9XX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1787633_2	313603.FB2170_07914	1.78e-173	556.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1HYY8@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TLS3_k127_1787633_1	1349822.NSB1T_06985	5.822e-223	700.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,2FNXD@200643|Bacteroidia,22W5I@171551|Porphyromonadaceae	976|Bacteroidetes	C	NADH dehydrogenase	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TLS3_k127_1787633_0	1517682.HW49_10535	3.071e-264	827.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,2FPCT@200643|Bacteroidia,22WP8@171551|Porphyromonadaceae	976|Bacteroidetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
TLS3_k127_1787633_3	1408473.JHXO01000002_gene3882	2.677e-35	138.0	COG0713@1|root,COG0713@2|Bacteria,4NR5Y@976|Bacteroidetes,2G3CR@200643|Bacteroidia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
TLS3_k127_1787633_4	1349822.NSB1T_07000	1.517e-34	138.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,2FPHK@200643|Bacteroidia,22XVS@171551|Porphyromonadaceae	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
TLS3_k127_1802845_5	1250278.JQNQ01000001_gene1821	2.951e-93	312.0	COG1001@1|root,COG1001@2|Bacteria,4NFD9@976|Bacteroidetes,1HWTB@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
TLS3_k127_1802845_0	869213.JCM21142_408	4.948e-249	783.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,47JCG@768503|Cytophagia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
TLS3_k127_1802845_12	172045.KS04_15645	5.302e-33	132.0	COG0319@1|root,COG0319@2|Bacteria,4NS93@976|Bacteroidetes,1I2W7@117743|Flavobacteriia,34RC9@308865|Elizabethkingia	976|Bacteroidetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	-	-	-	-	-	-	-	-	-	UPF0054
TLS3_k127_1802845_11	269798.CHU_3500	1.288e-33	134.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,47QUX@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
TLS3_k127_1802845_7	1408473.JHXO01000001_gene2101	8.318e-75	265.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,2FN4U@200643|Bacteroidia	976|Bacteroidetes	D	Peptidase, M23 family	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_1802845_13	886379.AEWI01000014_gene1461	4.395e-05	54.0	2EB7X@1|root,3358F@2|Bacteria,4PDGZ@976|Bacteroidetes,2G274@200643|Bacteroidia,3XK7I@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
TLS3_k127_1802845_8	709991.Odosp_2738	4.828e-70	260.0	COG0457@1|root,COG0457@2|Bacteria,4NDVW@976|Bacteroidetes,2FMY8@200643|Bacteroidia,22WHK@171551|Porphyromonadaceae	976|Bacteroidetes	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
TLS3_k127_1802845_9	547042.BACCOPRO_01905	2.941e-68	234.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,2FR7A@200643|Bacteroidia,4AP3D@815|Bacteroidaceae	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
TLS3_k127_1802845_10	880074.BARVI_04615	9.767e-60	216.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,2FMZ6@200643|Bacteroidia,22XHA@171551|Porphyromonadaceae	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
TLS3_k127_1802845_2	111105.HR09_06180	1.431e-144	465.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,2FNZN@200643|Bacteroidia,22W2R@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
TLS3_k127_1802845_6	1168034.FH5T_07905	3.025e-81	276.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,2FSG2@200643|Bacteroidia	976|Bacteroidetes	K	Bacterial regulatory proteins, crp family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TLS3_k127_1802845_3	411477.PARMER_02684	3.423e-134	434.0	COG0379@1|root,COG0379@2|Bacteria,4NDVX@976|Bacteroidetes,2FMT0@200643|Bacteroidia,22VXC@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
TLS3_k127_1802845_4	926562.Oweho_2308	2.708e-110	374.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia,2PBM8@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_1802845_1	1408473.JHXO01000001_gene2095	2.653e-167	531.0	COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,2FNZB@200643|Bacteroidia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
TLS3_k127_1802934_1	742817.HMPREF9449_00255	2.161e-38	147.0	COG1148@1|root,COG2072@1|root,COG1148@2|Bacteria,COG2072@2|Bacteria,4NI95@976|Bacteroidetes,2FRRV@200643|Bacteroidia,22Z3B@171551|Porphyromonadaceae	976|Bacteroidetes	CP	FAD binding domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Fer4,Fer4_7,HI0933_like,Pyr_redox_2
TLS3_k127_1802934_2	742817.HMPREF9449_00254	6.268e-33	132.0	COG1150@1|root,COG1150@2|Bacteria,4NTRW@976|Bacteroidetes,2FTYK@200643|Bacteroidia	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_7,Fer4_9
TLS3_k127_1802934_0	1121129.KB903359_gene2209	1.22e-176	573.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,2FRID@200643|Bacteroidia,22ZH9@171551|Porphyromonadaceae	976|Bacteroidetes	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
TLS3_k127_1803007_0	694427.Palpr_0372	1.514e-203	642.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,2FWIW@200643|Bacteroidia,22ZVB@171551|Porphyromonadaceae	976|Bacteroidetes	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
TLS3_k127_1803007_2	1121904.ARBP01000005_gene4640	2.212e-61	242.0	COG2208@1|root,COG2208@2|Bacteria,4NHV8@976|Bacteroidetes,47THS@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,SpoIIE
TLS3_k127_1803007_1	313606.M23134_04830	7.356e-96	351.0	COG3292@1|root,COG3292@2|Bacteria,4NNTX@976|Bacteroidetes,47U09@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	Y_Y_Y
TLS3_k127_1813797_4	1158338.JNLJ01000005_gene1533	2.749e-20	96.0	COG3054@1|root,COG3054@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (YtfJ_HI0045)	ytfJ	-	-	ko:K07109	-	-	-	-	ko00000	-	-	-	YtfJ_HI0045
TLS3_k127_1813797_5	401053.AciPR4_1318	1.259e-05	55.0	2E19M@1|root,2ZCDB@2|Bacteria,3Y4DH@57723|Acidobacteria,2JJ2T@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1813797_2	927658.AJUM01000042_gene1718	3.046e-95	319.0	COG1396@1|root,COG1396@2|Bacteria,4PP35@976|Bacteroidetes	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
TLS3_k127_1813797_0	927658.AJUM01000017_gene3084	2.967e-167	535.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,2G2UA@200643|Bacteroidia,3XJ3J@558415|Marinilabiliaceae	976|Bacteroidetes	L	impB/mucB/samB family	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
TLS3_k127_1813797_3	504487.JCM19302_1724	1.146e-28	118.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,1I40W@117743|Flavobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
TLS3_k127_1813797_1	926549.KI421517_gene3358	5.405e-161	520.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,47JNI@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
TLS3_k127_1819780_2	929562.Emtol_0864	3.769e-159	509.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,47JKY@768503|Cytophagia	976|Bacteroidetes	P	C-terminal region of aryl-sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
TLS3_k127_1819780_3	484018.BACPLE_01368	6.942e-155	504.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,2FP6T@200643|Bacteroidia,4AKST@815|Bacteroidaceae	976|Bacteroidetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TLS3_k127_1819780_0	504472.Slin_4261	6.585e-223	701.0	COG3119@1|root,COG3119@2|Bacteria,4NFC9@976|Bacteroidetes,47KWC@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
TLS3_k127_1819780_1	1168034.FH5T_07475	4.097e-201	636.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,2FMG2@200643|Bacteroidia	976|Bacteroidetes	P	Arylsulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TLS3_k127_1819780_4	1433126.BN938_0783	2.782e-58	209.0	COG1520@1|root,COG1520@2|Bacteria,4P15Y@976|Bacteroidetes,2FWBU@200643|Bacteroidia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2
TLS3_k127_1821277_0	1168034.FH5T_15230	0.0	1020.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,2FMXD@200643|Bacteroidia	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
TLS3_k127_1821277_2	1168034.FH5T_15345	3.385e-134	438.0	COG4299@1|root,COG4299@2|Bacteria,4NJZJ@976|Bacteroidetes,2FNJ9@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
TLS3_k127_1821277_1	1288963.ADIS_0251	3.059e-174	550.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_182648_7	472759.Nhal_0728	1.307e-53	192.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,1S4GM@1236|Gammaproteobacteria,1WYNP@135613|Chromatiales	135613|Chromatiales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_182648_5	1304874.JAFY01000007_gene2490	5.757e-91	332.0	COG4251@1|root,COG4936@1|root,COG4251@2|Bacteria,COG4936@2|Bacteria,3TCMP@508458|Synergistetes	2|Bacteria	T	GHKL domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HD,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,PocR
TLS3_k127_182648_3	1189619.pgond44_05355	2.446e-112	374.0	COG1503@1|root,COG1503@2|Bacteria,4NHJS@976|Bacteroidetes,1I0YD@117743|Flavobacteriia	976|Bacteroidetes	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_182648_2	1288963.ADIS_1306	1.675e-165	529.0	COG2271@1|root,COG2271@2|Bacteria,4PM8E@976|Bacteroidetes,47YKN@768503|Cytophagia	976|Bacteroidetes	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_182648_4	1123248.KB893314_gene3636	3.575e-102	339.0	COG2321@1|root,COG2321@2|Bacteria,4NDTZ@976|Bacteroidetes,1INUC@117747|Sphingobacteriia	976|Bacteroidetes	S	Neutral zinc metallopeptidase	ypfJ	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
TLS3_k127_182648_1	1191523.MROS_1418	2.347e-168	537.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	serA	GO:0003674,GO:0003824,GO:0004617,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008219,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0012501,GO:0016053,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0070905,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYL1228.KPN_03348	2-Hacid_dh,2-Hacid_dh_C,ACT,HAD
TLS3_k127_182648_8	1239962.C943_00843	4.061e-42	157.0	COG5646@1|root,COG5646@2|Bacteria,4NSDH@976|Bacteroidetes,47R0R@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_182648_6	517417.Cpar_0066	4.91e-58	207.0	COG0778@1|root,COG0778@2|Bacteria,1FEBI@1090|Chlorobi	1090|Chlorobi	C	PFAM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
TLS3_k127_182648_0	525257.HMPREF0204_13119	1.074e-320	996.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1HYU9@117743|Flavobacteriia,3ZTEE@59732|Chryseobacterium	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_1834779_3	743722.Sph21_2896	1.491e-146	473.0	COG0738@1|root,COG0738@2|Bacteria,4NFHM@976|Bacteroidetes,1IRGQ@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_1834779_7	1121899.Q764_10945	1.349e-05	57.0	COG4083@1|root,COG4083@2|Bacteria,4NM52@976|Bacteroidetes,1I1BK@117743|Flavobacteriia,2NWGW@237|Flavobacterium	976|Bacteroidetes	S	Transmembrane exosortase (Exosortase_EpsH)	groEL	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
TLS3_k127_1834779_6	1048983.EL17_05525	2.665e-29	119.0	2E3Q4@1|root,32YN3@2|Bacteria,4NVYD@976|Bacteroidetes,47RSR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1834779_5	1168034.FH5T_07910	7.124e-47	172.0	COG1765@1|root,COG1765@2|Bacteria,4NNTY@976|Bacteroidetes,2FU46@200643|Bacteroidia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
TLS3_k127_1834779_2	1123277.KB893180_gene2461	1.455e-171	545.0	COG3525@1|root,COG3525@2|Bacteria,4NGV2@976|Bacteroidetes,47TJT@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20
TLS3_k127_1834779_0	1123008.KB905692_gene148	0.0	1058.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,2FMEC@200643|Bacteroidia,22WNC@171551|Porphyromonadaceae	976|Bacteroidetes	P	Calcium-translocating P-type ATPase, PMCA-type	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
TLS3_k127_1834779_4	742817.HMPREF9449_02566	6.892e-67	241.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes	976|Bacteroidetes	F	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS3_k127_1834779_1	1408473.JHXO01000008_gene2886	1.539e-248	787.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,2FS4M@200643|Bacteroidia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_1839122_1	694427.Palpr_0170	1.562e-141	473.0	COG0577@1|root,COG0577@2|Bacteria,4NFGD@976|Bacteroidetes,2FNP6@200643|Bacteroidia,22VZ8@171551|Porphyromonadaceae	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1839122_6	485917.Phep_0679	1.201e-08	57.0	COG1940@1|root,COG1940@2|Bacteria,4NHNJ@976|Bacteroidetes,1IUUW@117747|Sphingobacteriia	976|Bacteroidetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
TLS3_k127_1839122_3	886379.AEWI01000022_gene146	3.09e-51	189.0	2E3CM@1|root,32YBW@2|Bacteria,4NQ4E@976|Bacteroidetes,2FSDU@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369
TLS3_k127_1839122_5	999419.HMPREF1077_00948	4.499e-17	86.0	COG0823@1|root,COG0823@2|Bacteria,4NGH4@976|Bacteroidetes,2FN8G@200643|Bacteroidia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_1839122_2	1168289.AJKI01000001_gene3622	3.983e-134	452.0	COG1629@1|root,COG4771@2|Bacteria,4PM07@976|Bacteroidetes,2FYI1@200643|Bacteroidia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_1839122_0	927658.AJUM01000046_gene32	8.154e-153	496.0	COG2133@1|root,COG2133@2|Bacteria,4NEZC@976|Bacteroidetes,2FSM8@200643|Bacteroidia,3XJVX@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,GSDH
TLS3_k127_1839122_4	483216.BACEGG_00329	2.076e-46	180.0	COG0845@1|root,COG4531@1|root,COG0845@2|Bacteria,COG4531@2|Bacteria,4NF6Y@976|Bacteroidetes,2FMZD@200643|Bacteroidia,4AMUN@815|Bacteroidaceae	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
TLS3_k127_1852995_1	153721.MYP_4960	4.84e-29	117.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,47MMM@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_1852995_0	925409.KI911562_gene1370	0.0	1076.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IR3P@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
TLS3_k127_1867558_1	1249975.JQLP01000005_gene2027	1.797e-55	198.0	COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,1HXX8@117743|Flavobacteriia,2P5M4@244698|Gillisia	976|Bacteroidetes	M	Transglycosylase SLT domain	mltD_2	-	-	-	-	-	-	-	-	-	-	-	SLT
TLS3_k127_1867558_0	886379.AEWI01000031_gene264	0.0	1215.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,2FNMG@200643|Bacteroidia,3XJ19@558415|Marinilabiliaceae	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
TLS3_k127_1871771_4	1408473.JHXO01000010_gene3773	6.395e-48	177.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,2FPCJ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
TLS3_k127_1871771_8	1211813.CAPH01000009_gene70	1.988e-24	103.0	COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,2FUZD@200643|Bacteroidia,22UKC@171550|Rikenellaceae	976|Bacteroidetes	J	Ribosomal L32p protein family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
TLS3_k127_1871771_2	679935.Alfi_0604	1.106e-103	345.0	COG0416@1|root,COG0416@2|Bacteria,4NHEX@976|Bacteroidetes,2G1NW@200643|Bacteroidia,22TZ9@171550|Rikenellaceae	976|Bacteroidetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
TLS3_k127_1871771_0	1120965.AUBV01000001_gene3158	1.574e-164	522.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,47KV4@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
TLS3_k127_1871771_6	1168289.AJKI01000002_gene2502	9.987e-37	142.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,2FUPU@200643|Bacteroidia,3XK7D@558415|Marinilabiliaceae	976|Bacteroidetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
TLS3_k127_1871771_10	1185876.BN8_04923	1.746e-10	64.0	2DQFZ@1|root,336KY@2|Bacteria,4NVIZ@976|Bacteroidetes,47SK8@768503|Cytophagia	976|Bacteroidetes	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
TLS3_k127_1871771_3	1408813.AYMG01000014_gene1578	1.781e-103	346.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1IPTF@117747|Sphingobacteriia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
TLS3_k127_1871771_9	1120951.AUBG01000015_gene3427	6.597e-21	93.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,1I53G@117743|Flavobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
TLS3_k127_1871771_5	1250278.JQNQ01000001_gene1939	4.699e-40	154.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1I239@117743|Flavobacteriia	976|Bacteroidetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
TLS3_k127_1871771_7	1168034.FH5T_08910	3.672e-34	138.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,2FQZ5@200643|Bacteroidia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
TLS3_k127_1871771_1	1168034.FH5T_08905	3.788e-141	451.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,2FM4H@200643|Bacteroidia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
TLS3_k127_1879686_0	1227739.Hsw_0611	6.038e-184	581.0	COG0538@1|root,COG0538@2|Bacteria,4PKW6@976|Bacteroidetes,47NMD@768503|Cytophagia	976|Bacteroidetes	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
TLS3_k127_1879686_1	886379.AEWI01000005_gene957	3.926e-181	577.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,2FPF3@200643|Bacteroidia,3XJB7@558415|Marinilabiliaceae	976|Bacteroidetes	C	Citrate synthase, C-terminal domain	prpC	-	2.3.3.1,2.3.3.5	ko:K01647,ko:K01659	ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351,R00931	RC00004,RC00067,RC00406,RC02827	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
TLS3_k127_1879686_2	118161.KB235922_gene5203	2.028e-152	493.0	COG0579@1|root,COG0579@2|Bacteria,1G4FU@1117|Cyanobacteria,3VITJ@52604|Pleurocapsales	1117|Cyanobacteria	C	Malate:quinone oxidoreductase (Mqo)	mqo	-	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Mqo
TLS3_k127_1890113_3	742766.HMPREF9455_01781	2.949e-16	84.0	2CK1R@1|root,32V4M@2|Bacteria,4NTYZ@976|Bacteroidetes,2FU5M@200643|Bacteroidia,22ZP3@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1890113_1	1408473.JHXO01000001_gene2146	1.216e-112	376.0	COG1453@1|root,COG1453@2|Bacteria,4NJU2@976|Bacteroidetes,2G2UD@200643|Bacteroidia	976|Bacteroidetes	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
TLS3_k127_1890113_2	1499967.BAYZ01000095_gene4075	2.186e-83	283.0	COG2220@1|root,COG2220@2|Bacteria,2NQD1@2323|unclassified Bacteria	2|Bacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
TLS3_k127_1890113_0	459349.CLOAM0984	5.791e-145	496.0	COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
TLS3_k127_1913145_1	861299.J421_4032	1.312e-99	332.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_4032|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1913145_0	335543.Sfum_1623	1.019e-133	445.0	COG3118@1|root,COG3118@2|Bacteria,1PQ8G@1224|Proteobacteria	1224|Proteobacteria	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
TLS3_k127_1913145_2	760192.Halhy_2464	1.024e-90	305.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,1IYH5@117747|Sphingobacteriia	976|Bacteroidetes	J	tRNA pseudouridine synthase	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
TLS3_k127_1913673_4	1286171.EAL2_c18860	1.069e-26	121.0	COG0438@1|root,COG0438@2|Bacteria,1VIP9@1239|Firmicutes,24SWT@186801|Clostridia	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
TLS3_k127_1913673_2	314282.PCNPT3_11730	8.126e-41	164.0	COG0438@1|root,COG0438@2|Bacteria,1NKTC@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_1913673_0	700598.Niako_7104	4.786e-73	261.0	COG0438@1|root,COG0438@2|Bacteria,4NPX0@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_1913673_3	196490.AUEZ01000014_gene2051	3.336e-34	143.0	COG0223@1|root,COG0223@2|Bacteria,1NN5V@1224|Proteobacteria,2TTHZ@28211|Alphaproteobacteria,3JRTG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1913673_5	768671.ThimaDRAFT_4749	8.273e-25	117.0	COG0438@1|root,COG0438@2|Bacteria,1RCC7@1224|Proteobacteria,1S51S@1236|Gammaproteobacteria,1X1N0@135613|Chromatiales	135613|Chromatiales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
TLS3_k127_1913673_1	96561.Dole_1797	2.967e-46	179.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,42T4H@68525|delta/epsilon subdivisions,2WPIT@28221|Deltaproteobacteria,2MM2A@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
TLS3_k127_1915569_5	926562.Oweho_1709	2.573e-52	197.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,1HWNJ@117743|Flavobacteriia,2PBHW@246874|Cryomorphaceae	976|Bacteroidetes	T	regulator of cell autolysis	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_1915569_2	945713.IALB_0123	7.063e-84	285.0	COG3279@1|root,COG3279@2|Bacteria	2|Bacteria	KT	phosphorelay signal transduction system	lytT	-	-	ko:K02477,ko:K07705,ko:K11641	ko02020,map02020	M00492,M00494	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_1915569_6	865937.Gilli_2608	7.745e-29	123.0	COG3047@1|root,COG3047@2|Bacteria,4NQHT@976|Bacteroidetes,1I34A@117743|Flavobacteriia,2P7NF@244698|Gillisia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_1915569_0	1168034.FH5T_09815	9.174e-146	473.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,2FM7Y@200643|Bacteroidia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
TLS3_k127_1915569_9	1124780.ANNU01000032_gene1233	1.835e-16	91.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PSU@768503|Cytophagia	976|Bacteroidetes	S	PFAM MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_1915569_1	1123008.KB905697_gene3138	7.329e-95	326.0	COG2885@1|root,COG2885@2|Bacteria,4NI3U@976|Bacteroidetes,2FQF1@200643|Bacteroidia,230CU@171551|Porphyromonadaceae	976|Bacteroidetes	M	OmpA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl_2,OmpA
TLS3_k127_1915569_4	1168034.FH5T_08585	1.797e-60	214.0	COG1225@1|root,COG1225@2|Bacteria,4NQCB@976|Bacteroidetes,2FXA6@200643|Bacteroidia	976|Bacteroidetes	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
TLS3_k127_1915569_8	1279009.ADICEAN_01361	1.489e-16	92.0	COG3386@1|root,COG3386@2|Bacteria,4NYVH@976|Bacteroidetes,47XBY@768503|Cytophagia	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1915569_7	502025.Hoch_1375	3.311e-20	104.0	COG2304@1|root,COG2304@2|Bacteria,1PDQV@1224|Proteobacteria,43CYI@68525|delta/epsilon subdivisions,2X86P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
TLS3_k127_1916223_3	1408813.AYMG01000011_gene726	5.006e-54	196.0	COG0457@1|root,COG0457@2|Bacteria,4NPX1@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
TLS3_k127_1916223_1	1408473.JHXO01000010_gene3641	2.148e-157	522.0	COG0739@1|root,COG4413@1|root,COG0739@2|Bacteria,COG4413@2|Bacteria,4NJUQ@976|Bacteroidetes	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,UT
TLS3_k127_1916223_0	1408813.AYMG01000011_gene730	1.223e-199	630.0	COG0019@1|root,COG0019@2|Bacteria,4NGRF@976|Bacteroidetes	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS3_k127_1916223_2	1408813.AYMG01000011_gene731	2.229e-135	439.0	COG0151@1|root,COG0151@2|Bacteria,4NK50@976|Bacteroidetes	976|Bacteroidetes	F	Belongs to the GarS family	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
TLS3_k127_1916223_5	1408813.AYMG01000011_gene732	2.153e-16	81.0	2EBCA@1|root,335D0@2|Bacteria,4NUYY@976|Bacteroidetes	976|Bacteroidetes	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
TLS3_k127_1916223_4	1168034.FH5T_13325	7.357e-51	185.0	COG1940@1|root,COG1940@2|Bacteria,4NM8T@976|Bacteroidetes,2FSJS@200643|Bacteroidia	976|Bacteroidetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
TLS3_k127_1946827_4	1121870.AUAA01000010_gene1675	1.108e-24	106.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1HWTZ@117743|Flavobacteriia,3HGWW@358033|Chryseobacterium	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
TLS3_k127_1946827_0	484018.BACPLE_03002	3.33e-181	584.0	COG0737@1|root,COG0737@2|Bacteria,4NGIB@976|Bacteroidetes,2FNGG@200643|Bacteroidia,4AKWZ@815|Bacteroidaceae	976|Bacteroidetes	F	Belongs to the 5'-nucleotidase family	cpdB	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
TLS3_k127_1946827_1	1313304.CALK_2213	7.492e-117	389.0	COG3876@1|root,COG3876@2|Bacteria	2|Bacteria	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
TLS3_k127_1946827_3	1408473.JHXO01000009_gene3425	8.372e-25	108.0	COG5002@1|root,COG5002@2|Bacteria,4PKV1@976|Bacteroidetes,2G0ES@200643|Bacteroidia	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_1946827_2	385682.AFSL01000027_gene615	9.92e-52	186.0	COG0234@1|root,COG0234@2|Bacteria,4NRE1@976|Bacteroidetes,2FTDY@200643|Bacteroidia,3XJZ8@558415|Marinilabiliaceae	976|Bacteroidetes	O	Chaperonin 10 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cpn10
TLS3_k127_1954713_3	1123248.KB893381_gene1007	9.142e-19	90.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cupredoxin_1
TLS3_k127_1954713_0	1168034.FH5T_05345	0.0	1400.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,2FM7V@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
TLS3_k127_1954713_1	1408473.JHXO01000001_gene2418	2.652e-109	366.0	COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,2FQ2Q@200643|Bacteroidia	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_1954713_2	742817.HMPREF9449_02623	3.295e-70	243.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,2FPNN@200643|Bacteroidia,22XY4@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
TLS3_k127_1972705_1	1033732.CAHI01000008_gene1783	2.666e-153	507.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
TLS3_k127_1972705_2	888832.HMPREF9420_1920	1.267e-115	392.0	COG1435@1|root,COG1435@2|Bacteria,4NE0A@976|Bacteroidetes,2FM03@200643|Bacteroidia	976|Bacteroidetes	F	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_1972705_0	485917.Phep_1124	5.077e-176	586.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
TLS3_k127_1972705_3	1268240.ATFI01000001_gene2728	1.265e-74	268.0	COG5434@1|root,COG5434@2|Bacteria,4NICS@976|Bacteroidetes,2FMGC@200643|Bacteroidia,4APJS@815|Bacteroidaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28
TLS3_k127_1984936_2	1122176.KB903531_gene3073	1.069e-210	695.0	COG2312@1|root,COG2312@2|Bacteria,4PP0J@976|Bacteroidetes	976|Bacteroidetes	E	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD
TLS3_k127_1984936_12	880073.Calab_2401	9.696e-10	73.0	COG2374@1|root,COG2374@2|Bacteria,2NRB5@2323|unclassified Bacteria	2|Bacteria	G	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,FlgD_ig,LTD
TLS3_k127_1984936_8	1122603.ATVI01000005_gene3305	6.258e-51	192.0	COG1409@1|root,COG1409@2|Bacteria,1NXRI@1224|Proteobacteria,1S1N6@1236|Gammaproteobacteria,1XB9J@135614|Xanthomonadales	135614|Xanthomonadales	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
TLS3_k127_1984936_1	1047013.AQSP01000113_gene739	1.179e-225	708.0	COG4868@1|root,COG4868@2|Bacteria,2NQM9@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1846)	XK27_07020	-	-	-	-	-	-	-	-	-	-	-	DUF1846
TLS3_k127_1984936_6	927658.AJUM01000042_gene1631	1.38e-64	229.0	COG2865@1|root,COG2865@2|Bacteria,4NGPG@976|Bacteroidetes,2FMWB@200643|Bacteroidia,3XIJM@558415|Marinilabiliaceae	976|Bacteroidetes	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
TLS3_k127_1984936_0	1124780.ANNU01000025_gene3340	0.0	1035.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,47JGX@768503|Cytophagia	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,PD40
TLS3_k127_1984936_9	1296416.JACB01000017_gene5141	6.776e-48	181.0	COG0500@1|root,COG2226@2|Bacteria,4PH0U@976|Bacteroidetes,1IHRF@117743|Flavobacteriia,2YIT4@290174|Aquimarina	976|Bacteroidetes	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_1984936_4	1227739.Hsw_1309	1.241e-135	439.0	COG2502@1|root,COG2502@2|Bacteria,4NFZA@976|Bacteroidetes,47MAY@768503|Cytophagia	976|Bacteroidetes	E	Aspartate-ammonia ligase	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
TLS3_k127_1984936_7	1121904.ARBP01000005_gene4834	1.737e-61	223.0	COG3386@1|root,COG3386@2|Bacteria,4NJKD@976|Bacteroidetes,47PXA@768503|Cytophagia	976|Bacteroidetes	G	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
TLS3_k127_1984936_3	1288963.ADIS_4714	7.063e-170	542.0	COG3693@1|root,COG3693@2|Bacteria,4NE5Z@976|Bacteroidetes,47Q9Y@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 10	xynT	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_4_9,Glyco_hydro_10
TLS3_k127_1984936_5	1279009.ADICEAN_00044	1.989e-101	338.0	COG3832@1|root,COG3832@2|Bacteria,4NQ4A@976|Bacteroidetes,47QHI@768503|Cytophagia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_1984936_10	509635.N824_26965	2.67e-29	121.0	2E3B3@1|root,32YAM@2|Bacteria,4NW81@976|Bacteroidetes,1ITTZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
TLS3_k127_1984936_11	1227739.Hsw_2367	1.07e-20	94.0	COG0526@1|root,COG0526@2|Bacteria,4NQ9U@976|Bacteroidetes,47RGU@768503|Cytophagia	976|Bacteroidetes	CO	Thioredoxin	trxC	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin,Thioredoxin_8
TLS3_k127_1995390_1	204669.Acid345_1359	2.132e-106	381.0	COG3250@1|root,COG3250@2|Bacteria,3Y2PR@57723|Acidobacteria,2JIC7@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyl hydrolases family 2	-	-	3.2.1.165	ko:K15855	ko00520,ko01100,map00520,map01100	-	R01966	RC00049	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2
TLS3_k127_1995390_0	1288963.ADIS_2398	1.449e-150	487.0	COG1073@1|root,COG1073@2|Bacteria,4NG6A@976|Bacteroidetes,47MDZ@768503|Cytophagia	976|Bacteroidetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1995390_2	1150600.ADIARSV_2631	2.156e-85	293.0	COG0584@1|root,COG0584@2|Bacteria,4NE2E@976|Bacteroidetes,1IRVM@117747|Sphingobacteriia	976|Bacteroidetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	DUF4996,GDPD
TLS3_k127_1995390_3	641524.ADICYQ_3919	1.691e-08	59.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,47KSM@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TLS3_k127_19959_5	1168034.FH5T_04715	4.222e-24	106.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,2FMIK@200643|Bacteroidia	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
TLS3_k127_19959_1	1168034.FH5T_04710	2.632e-83	283.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,2FNMJ@200643|Bacteroidia	976|Bacteroidetes	S	Peptidase, S54 family	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
TLS3_k127_19959_2	1408473.JHXO01000010_gene3597	1.236e-76	266.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,2FMGW@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TLS3_k127_19959_3	1408473.JHXO01000010_gene3598	2.887e-72	258.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,2FNIX@200643|Bacteroidia	976|Bacteroidetes	S	endonuclease exonuclease phosphatase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_19959_0	1408473.JHXO01000010_gene3609	6.704e-116	382.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,2FX64@200643|Bacteroidia	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_19959_4	694427.Palpr_0202	4.863e-49	183.0	COG1592@1|root,COG1592@2|Bacteria	2|Bacteria	C	Rubrerythrin	-	-	1.15.1.2	ko:K05919,ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko02000	2.A.6.1.4,8.A.1	-	-	Desulfoferrod_N,HlyD_D23,Rubrerythrin
TLS3_k127_19959_6	385682.AFSL01000056_gene1963	1.165e-10	61.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia,3XJVI@558415|Marinilabiliaceae	976|Bacteroidetes	C	Inorganic H+ pyrophosphatase	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
TLS3_k127_1998703_1	1122605.KB893647_gene361	7.625e-70	242.0	COG1520@1|root,COG1520@2|Bacteria,4NHU3@976|Bacteroidetes,1IR46@117747|Sphingobacteriia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1998703_2	869213.JCM21142_72971	1.12e-33	149.0	COG0666@1|root,COG0666@2|Bacteria,4NVXX@976|Bacteroidetes	976|Bacteroidetes	S	Ankyrin repeat protein	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4
TLS3_k127_1998703_0	999419.HMPREF1077_00314	2.556e-217	691.0	COG3119@1|root,COG3119@2|Bacteria,4NEZJ@976|Bacteroidetes,2FMY4@200643|Bacteroidia,22Z5B@171551|Porphyromonadaceae	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TLS3_k127_200612_4	36875.HQ29_02125	1.926e-58	204.0	COG0094@1|root,COG0094@2|Bacteria,4NEGY@976|Bacteroidetes,2FM5Y@200643|Bacteroidia,22VVF@171551|Porphyromonadaceae	976|Bacteroidetes	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
TLS3_k127_200612_7	742817.HMPREF9449_02682	7.679e-40	151.0	COG0199@1|root,COG0199@2|Bacteria,4NQ6N@976|Bacteroidetes,2FTD0@200643|Bacteroidia,22Y99@171551|Porphyromonadaceae	976|Bacteroidetes	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
TLS3_k127_200612_5	1168289.AJKI01000011_gene459	7.181e-56	197.0	COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes,2FRZ6@200643|Bacteroidia,3XK5S@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal protein S8	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
TLS3_k127_200612_1	742725.HMPREF9450_00070	2.268e-74	254.0	COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,2FNEG@200643|Bacteroidia,22UZ3@171550|Rikenellaceae	976|Bacteroidetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
TLS3_k127_200612_6	445970.ALIPUT_00646	4.665e-42	157.0	COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia,22VD9@171550|Rikenellaceae	976|Bacteroidetes	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
TLS3_k127_200612_0	1408473.JHXO01000006_gene1299	1.489e-84	282.0	COG0098@1|root,COG0098@2|Bacteria,4NG1Z@976|Bacteroidetes,2FMI8@200643|Bacteroidia	976|Bacteroidetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
TLS3_k127_200612_8	880073.Calab_2144	1.957e-17	84.0	COG1841@1|root,COG1841@2|Bacteria,2NQ1P@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein L30	rpmD	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
TLS3_k127_200612_2	869213.JCM21142_31265	2.797e-63	220.0	COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,47PP0@768503|Cytophagia	976|Bacteroidetes	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
TLS3_k127_200612_3	1168289.AJKI01000011_gene453	9.288e-60	209.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,2FPIT@200643|Bacteroidia,3XISD@558415|Marinilabiliaceae	976|Bacteroidetes	U	SecY translocase	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
TLS3_k127_2010638_2	688270.Celal_0827	4.494e-47	188.0	2ANCY@1|root,31DBH@2|Bacteria,4NS5C@976|Bacteroidetes,1I5GQ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2010638_3	694427.Palpr_2048	9.099e-26	112.0	2A1C4@1|root,30PJ1@2|Bacteria,4PC57@976|Bacteroidetes,2G001@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2010638_0	688270.Celal_0825	1.777e-111	376.0	COG0206@1|root,COG0206@2|Bacteria,4NG5V@976|Bacteroidetes,1I0G2@117743|Flavobacteriia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	-	-	-	-	-	-	-	-	-	Tubulin
TLS3_k127_2010638_1	1124780.ANNU01000046_gene2243	3.557e-95	340.0	COG0849@1|root,COG0849@2|Bacteria,4PNJ7@976|Bacteroidetes,47YJ0@768503|Cytophagia	976|Bacteroidetes	D	cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2021461_1	1313421.JHBV01000049_gene75	4.617e-169	540.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes	976|Bacteroidetes	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
TLS3_k127_2021461_5	1168034.FH5T_06905	3.748e-24	104.0	COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,2FUIM@200643|Bacteroidia	976|Bacteroidetes	C	ATP synthase, delta epsilon subunit, beta-sandwich domain protein	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
TLS3_k127_2021461_0	926562.Oweho_2862	4.511e-259	805.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1HWM2@117743|Flavobacteriia,2PAC3@246874|Cryomorphaceae	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
TLS3_k127_2021461_4	929556.Solca_1217	1.695e-95	322.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1INSC@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
TLS3_k127_2021461_3	1168034.FH5T_08900	2.406e-105	349.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,2FP5N@200643|Bacteroidia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
TLS3_k127_2021461_2	1168289.AJKI01000002_gene2496	6.035e-148	472.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,2FM4H@200643|Bacteroidia,3XJ5E@558415|Marinilabiliaceae	976|Bacteroidetes	C	ATP synthase alpha/beta chain, C terminal domain	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
TLS3_k127_2045728_3	679199.HMPREF9332_01782	1.727e-64	229.0	COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,2FMRQ@200643|Bacteroidia,1WD15@1283313|Alloprevotella	976|Bacteroidetes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
TLS3_k127_2045728_2	1168289.AJKI01000014_gene2072	1.285e-72	250.0	COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes,2FRYA@200643|Bacteroidia,3XJ8R@558415|Marinilabiliaceae	976|Bacteroidetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_2045728_1	1178825.ALIH01000008_gene712	4.712e-80	284.0	COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,1HXJW@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_2045728_0	866536.Belba_0430	1.83e-169	540.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,47JEY@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
TLS3_k127_2045728_4	1168289.AJKI01000014_gene2069	2.553e-55	198.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,2FM2K@200643|Bacteroidia,3XIMV@558415|Marinilabiliaceae	976|Bacteroidetes	S	Predicted permease YjgP/YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
TLS3_k127_2055422_2	768710.DesyoDRAFT_0198	2.189e-84	283.0	COG0288@1|root,COG0288@2|Bacteria,1VSV8@1239|Firmicutes,24GE5@186801|Clostridia,2652J@186807|Peptococcaceae	186801|Clostridia	P	Carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
TLS3_k127_2055422_1	865937.Gilli_1738	6.672e-176	558.0	COG1373@1|root,COG1373@2|Bacteria,4NE3E@976|Bacteroidetes,1HYK8@117743|Flavobacteriia	976|Bacteroidetes	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14
TLS3_k127_2055422_0	1499967.BAYZ01000119_gene3213	1.812e-182	585.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N
TLS3_k127_2066311_1	742817.HMPREF9449_00713	5.376e-55	203.0	COG1957@1|root,COG2191@1|root,COG1957@2|Bacteria,COG2191@2|Bacteria,4PITJ@976|Bacteroidetes,2FXEM@200643|Bacteroidia	976|Bacteroidetes	CF	FmdE, Molybdenum formylmethanofuran dehydrogenase operon	-	-	-	ko:K01250	-	-	-	-	ko00000,ko01000	-	-	-	FmdE,IU_nuc_hydro
TLS3_k127_2066311_2	865937.Gilli_1731	1.271e-44	165.0	COG0614@1|root,COG0614@2|Bacteria,4NQQ6@976|Bacteroidetes,1I4E1@117743|Flavobacteriia	976|Bacteroidetes	P	GxxExxY protein	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
TLS3_k127_2066311_0	927658.AJUM01000022_gene1295	3.26e-272	844.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,4NE85@976|Bacteroidetes,2FNPE@200643|Bacteroidia	976|Bacteroidetes	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumB	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
TLS3_k127_2073792_2	1158294.JOMI01000002_gene2860	3.647e-72	246.0	COG0794@1|root,COG0794@2|Bacteria,4NED8@976|Bacteroidetes,2FMXM@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS
TLS3_k127_2073792_0	926549.KI421517_gene2439	8.246e-152	491.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,47K89@768503|Cytophagia	976|Bacteroidetes	G	TIGRFAM glucose galactose transporter	gluP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
TLS3_k127_2073792_1	929556.Solca_2716	3.662e-111	370.0	COG2334@1|root,COG2334@2|Bacteria,4NH00@976|Bacteroidetes,1INVB@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Aminoglycoside phosphotransferase	mdsC	-	-	-	-	-	-	-	-	-	-	-	APH
TLS3_k127_2073792_3	1499967.BAYZ01000009_gene5260	1.185e-61	218.0	2AY4N@1|root,31Q6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2087286_1	203275.BFO_3146	3.264e-192	607.0	COG1082@1|root,COG2133@1|root,COG1082@2|Bacteria,COG2133@2|Bacteria,4NFKF@976|Bacteroidetes,2FRR2@200643|Bacteroidia,22XIX@171551|Porphyromonadaceae	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_2087286_0	1270193.JARP01000004_gene1513	2.403e-267	841.0	COG1554@1|root,COG1554@2|Bacteria,4NFYU@976|Bacteroidetes,1I0QT@117743|Flavobacteriia,2NUT4@237|Flavobacterium	976|Bacteroidetes	G	hydrolase, family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2091313_0	880073.Calab_3460	1.062e-68	238.0	COG2008@1|root,COG2008@2|Bacteria,2NP02@2323|unclassified Bacteria	2|Bacteria	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
TLS3_k127_2091313_1	1121094.KB894657_gene2555	1.275e-39	157.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,2FM72@200643|Bacteroidia,4AKT0@815|Bacteroidaceae	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_2091313_2	411479.BACUNI_02457	8.557e-39	153.0	COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,2FM45@200643|Bacteroidia,4ANCH@815|Bacteroidaceae	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	exbD2	-	-	-	-	-	-	-	-	-	-	-	ExbD
TLS3_k127_2091313_3	1121129.KB903359_gene1128	3.608e-27	115.0	COG0848@1|root,COG0848@2|Bacteria,4NMT4@976|Bacteroidetes,2FQHV@200643|Bacteroidia,22XSU@171551|Porphyromonadaceae	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	exbD1	-	-	-	-	-	-	-	-	-	-	-	ExbD
TLS3_k127_2106730_0	1121481.AUAS01000003_gene3781	1.784e-218	683.0	COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,47M0H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_2106730_1	1237149.C900_05477	4.961e-40	154.0	COG1595@1|root,COG1595@2|Bacteria,4NMYQ@976|Bacteroidetes,47PII@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_2106730_2	714943.Mucpa_5285	1.831e-28	124.0	COG1413@1|root,COG1413@2|Bacteria,4NIBA@976|Bacteroidetes,1IU6E@117747|Sphingobacteriia	976|Bacteroidetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,zf-HC2
TLS3_k127_2129016_5	1122929.KB908218_gene1482	5.128e-32	126.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	DUF707
TLS3_k127_2129016_0	439235.Dalk_1316	2.215e-198	622.0	COG0037@1|root,COG0037@2|Bacteria,1NKHX@1224|Proteobacteria,42PFP@68525|delta/epsilon subdivisions,2WKYC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	TIGRFAM N-acetyl sugar amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_synthase
TLS3_k127_2129016_3	1131269.AQVV01000034_gene2265	1.84e-72	250.0	COG0118@1|root,COG0118@2|Bacteria	2|Bacteria	E	glutamine metabolic process	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
TLS3_k127_2129016_2	307480.IW16_19695	7.858e-101	336.0	COG0107@1|root,COG0107@2|Bacteria,4NM6U@976|Bacteroidetes,1I1G9@117743|Flavobacteriia,3ZPM1@59732|Chryseobacterium	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	-	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
TLS3_k127_2129016_1	1235803.C825_00358	5.621e-135	447.0	COG5360@1|root,COG5360@2|Bacteria,4NHMA@976|Bacteroidetes,2G2Q8@200643|Bacteroidia,2313F@171551|Porphyromonadaceae	976|Bacteroidetes	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
TLS3_k127_2129016_4	1185876.BN8_00557	1.216e-44	166.0	COG0438@1|root,COG0438@2|Bacteria,4NK2C@976|Bacteroidetes,47NQ5@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase 4-like domain	orfL	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
TLS3_k127_2141115_0	234267.Acid_0198	2.869e-250	802.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,DUF3298,DUF4163,Glyco_hydro_9,Polysacc_deac_1
TLS3_k127_2141115_1	880072.Desac_1935	1.651e-11	74.0	COG2006@1|root,COG2006@2|Bacteria,1R7BH@1224|Proteobacteria,42QGJ@68525|delta/epsilon subdivisions,2WJ1A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
TLS3_k127_214443_0	1408473.JHXO01000008_gene2677	4.114e-202	645.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
TLS3_k127_2191665_9	926562.Oweho_1899	8.004e-66	231.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1HYKR@117743|Flavobacteriia,2PC26@246874|Cryomorphaceae	976|Bacteroidetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
TLS3_k127_2191665_13	1121129.KB903360_gene3315	3.021e-58	209.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,2FPYK@200643|Bacteroidia,22WRV@171551|Porphyromonadaceae	976|Bacteroidetes	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
TLS3_k127_2191665_10	385682.AFSL01000105_gene126	8.419e-64	228.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,2G23G@200643|Bacteroidia,3XIX7@558415|Marinilabiliaceae	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
TLS3_k127_2191665_7	1168289.AJKI01000040_gene3125	1.091e-80	272.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,2FP84@200643|Bacteroidia,3XJC3@558415|Marinilabiliaceae	976|Bacteroidetes	J	Elongation factor P (EF-P) OB domain	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
TLS3_k127_2191665_6	869213.JCM21142_104136	2.888e-96	330.0	COG2208@1|root,COG2208@2|Bacteria,4NI98@976|Bacteroidetes,47KA0@768503|Cytophagia	976|Bacteroidetes	KT	PFAM Stage II sporulation protein E (SpoIIE)	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
TLS3_k127_2191665_0	1168034.FH5T_03515	9.41e-213	667.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,2FN0B@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
TLS3_k127_2191665_15	1168034.FH5T_03555	1.193e-35	144.0	COG1286@1|root,COG1286@2|Bacteria,4NRG9@976|Bacteroidetes,2G2B1@200643|Bacteroidia	976|Bacteroidetes	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
TLS3_k127_2191665_8	1048983.EL17_01260	3.868e-78	269.0	2DBB1@1|root,2Z854@2|Bacteria,4NNZD@976|Bacteroidetes,47Q80@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
TLS3_k127_2191665_12	1232453.BAIF02000063_gene1792	1.156e-58	222.0	COG2159@1|root,COG2159@2|Bacteria,1UZI6@1239|Firmicutes,24EHD@186801|Clostridia	186801|Clostridia	G	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
TLS3_k127_2191665_2	1121286.AUMT01000005_gene3203	1.445e-134	445.0	COG1807@1|root,COG1807@2|Bacteria,4NHXW@976|Bacteroidetes,1I0KK@117743|Flavobacteriia,3ZQVY@59732|Chryseobacterium	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_2191665_11	945713.IALB_3196	1.443e-60	218.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	DUF4349
TLS3_k127_2191665_3	1168034.FH5T_17420	2.169e-102	340.0	arCOG10218@1|root,320QR@2|Bacteria	2|Bacteria	C	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
TLS3_k127_2191665_1	1408473.JHXO01000007_gene697	2.618e-186	588.0	COG0798@1|root,COG0798@2|Bacteria,4NFG7@976|Bacteroidetes,2FN4J@200643|Bacteroidia	976|Bacteroidetes	P	COG0798 Arsenite efflux pump ACR3 and related	acr3	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
TLS3_k127_2191665_5	153721.MYP_3342	5.899e-100	333.0	COG0500@1|root,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,47MVN@768503|Cytophagia	976|Bacteroidetes	Q	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
TLS3_k127_2191665_20	865937.Gilli_1678	7.685e-11	65.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,1IGHH@117743|Flavobacteriia,2P7PF@244698|Gillisia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
TLS3_k127_2191665_14	226186.BT_0115	1.972e-55	197.0	COG0394@1|root,COG0394@2|Bacteria,4NNN6@976|Bacteroidetes,2FSB5@200643|Bacteroidia,4AQMX@815|Bacteroidaceae	976|Bacteroidetes	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
TLS3_k127_2191665_16	1168034.FH5T_14845	1.797e-33	132.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,2FYHY@200643|Bacteroidia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
TLS3_k127_2191665_17	1408473.JHXO01000007_gene710	1.427e-32	130.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,2FT4U@200643|Bacteroidia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
TLS3_k127_2191665_19	1408473.JHXO01000007_gene709	4.647e-24	103.0	COG0526@1|root,COG0526@2|Bacteria,4NUP1@976|Bacteroidetes,2FUJZ@200643|Bacteroidia	976|Bacteroidetes	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
TLS3_k127_2191665_18	694427.Palpr_1798	4.471e-28	118.0	2E9PV@1|root,333W7@2|Bacteria,4NT8I@976|Bacteroidetes,2FT1D@200643|Bacteroidia,22YJ4@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2191665_4	1408473.JHXO01000007_gene707	1.301e-100	332.0	COG0785@1|root,COG0785@2|Bacteria,4PKGI@976|Bacteroidetes,2G3GF@200643|Bacteroidia	976|Bacteroidetes	O	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
TLS3_k127_2200138_3	675812.VHA_002080	4.127e-32	126.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,1XTFI@135623|Vibrionales	135623|Vibrionales	O	COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1	fklB	-	5.2.1.8	ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
TLS3_k127_2200138_2	927658.AJUM01000022_gene1007	1.919e-79	267.0	COG0652@1|root,COG0652@2|Bacteria,4NKQ7@976|Bacteroidetes,2FSSH@200643|Bacteroidia,3XK0C@558415|Marinilabiliaceae	976|Bacteroidetes	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
TLS3_k127_2200138_4	886379.AEWI01000054_gene2612	3.786e-29	122.0	COG0629@1|root,COG0629@2|Bacteria,4PDPI@976|Bacteroidetes,2G27T@200643|Bacteroidia,3XK96@558415|Marinilabiliaceae	976|Bacteroidetes	L	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
TLS3_k127_2200138_0	709991.Odosp_0350	7.349e-256	805.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,2FN8J@200643|Bacteroidia,22X1E@171551|Porphyromonadaceae	976|Bacteroidetes	E	peptidase	dcp	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
TLS3_k127_2200138_1	1408473.JHXO01000005_gene1852	7.451e-168	534.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,2FM2Z@200643|Bacteroidia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
TLS3_k127_2200238_0	471854.Dfer_2166	5.439e-157	509.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,47M3C@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
TLS3_k127_2200238_1	886293.Sinac_5964	1.388e-148	495.0	COG5029@1|root,COG5029@2|Bacteria,2J2JG@203682|Planctomycetes	203682|Planctomycetes	O	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
TLS3_k127_2202325_0	869213.JCM21142_104512	7.126e-210	664.0	COG4651@1|root,COG4651@2|Bacteria	2|Bacteria	P	solute:proton antiporter activity	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
TLS3_k127_2202325_1	1124780.ANNU01000016_gene1811	1.211e-66	233.0	COG0526@1|root,COG0526@2|Bacteria,4PKPR@976|Bacteroidetes,47PBI@768503|Cytophagia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TLS3_k127_2202325_2	1250006.JHZZ01000001_gene3320	1.438e-30	123.0	COG0526@1|root,COG0526@2|Bacteria,4NQ9U@976|Bacteroidetes,1I2Z8@117743|Flavobacteriia,3VWHG@52959|Polaribacter	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin
TLS3_k127_2205402_0	1408473.JHXO01000008_gene2755	2.411e-249	781.0	COG1164@1|root,COG1164@2|Bacteria,4NFV3@976|Bacteroidetes,2FMG8@200643|Bacteroidia	976|Bacteroidetes	E	Oligoendopeptidase f	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2205402_1	1121859.KB890755_gene1169	9.098e-202	636.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,47KQM@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
TLS3_k127_2205402_2	387092.NIS_0282	2.437e-12	67.0	COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,42RIS@68525|delta/epsilon subdivisions,2YQBI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C
TLS3_k127_2228024_1	1047013.AQSP01000134_gene1334	1.928e-48	177.0	COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
TLS3_k127_2228024_0	1047013.AQSP01000104_gene1414	2.257e-244	763.0	COG0312@1|root,COG0312@2|Bacteria,2NPIS@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
TLS3_k127_2228603_3	867902.Ornrh_1969	1.998e-09	67.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes,1HYQM@117743|Flavobacteriia	976|Bacteroidetes	D	sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
TLS3_k127_2228603_0	1408473.JHXO01000001_gene2257	0.0	1072.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,2FNV6@200643|Bacteroidia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
TLS3_k127_2228603_1	525373.HMPREF0766_10245	5.834e-77	269.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,1IPHC@117747|Sphingobacteriia	976|Bacteroidetes	V	peptidase	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
TLS3_k127_2228603_2	709991.Odosp_0782	4.616e-73	252.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,2FP71@200643|Bacteroidia,22XBI@171551|Porphyromonadaceae	976|Bacteroidetes	E	Alanine dehydrogenase/PNT, N-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
TLS3_k127_2242584_3	1408473.JHXO01000005_gene1823	9.692e-62	234.0	COG4206@1|root,COG4206@2|Bacteria,4NED9@976|Bacteroidetes,2FMA6@200643|Bacteroidia	976|Bacteroidetes	H	COG4206 Outer membrane cobalamin receptor protein	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
TLS3_k127_2242584_2	929556.Solca_0618	3.817e-68	244.0	COG3391@1|root,COG3391@2|Bacteria,4NESV@976|Bacteroidetes,1IQIX@117747|Sphingobacteriia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2
TLS3_k127_2242584_1	1408473.JHXO01000007_gene983	2.952e-80	281.0	COG0614@1|root,COG0614@2|Bacteria,4NH9F@976|Bacteroidetes,2FMDS@200643|Bacteroidia	976|Bacteroidetes	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
TLS3_k127_2242584_0	1408473.JHXO01000007_gene982	2.061e-104	349.0	COG0609@1|root,COG0609@2|Bacteria,4NEDU@976|Bacteroidetes,2FNDK@200643|Bacteroidia	976|Bacteroidetes	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
TLS3_k127_2246_4	1168034.FH5T_17590	3.927e-57	205.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,2G2QE@200643|Bacteroidia	976|Bacteroidetes	O	Psort location Extracellular, score	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
TLS3_k127_2246_2	1168034.FH5T_01790	2.166e-101	337.0	2AMSR@1|root,31CP7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2246_3	1168034.FH5T_20650	3.025e-65	228.0	COG1595@1|root,COG1595@2|Bacteria,4NMAK@976|Bacteroidetes,2G2W5@200643|Bacteroidia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_2246_6	1408473.JHXO01000012_gene451	6.794e-21	100.0	2EPCT@1|root,33GZF@2|Bacteria,4NZ8X@976|Bacteroidetes,2FVPB@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2246_5	742817.HMPREF9449_01232	3.719e-38	157.0	COG3595@1|root,COG3595@2|Bacteria,4NEUW@976|Bacteroidetes,2FV2Q@200643|Bacteroidia,22YZE@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2246_1	1166018.FAES_1629	1.351e-110	367.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,47K5N@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
TLS3_k127_2246_0	616991.JPOO01000001_gene2849	6.649e-196	622.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1HYVB@117743|Flavobacteriia,23GJJ@178469|Arenibacter	976|Bacteroidetes	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
TLS3_k127_225714_11	1211813.CAPH01000009_gene227	9.424e-08	62.0	COG0526@1|root,COG0526@2|Bacteria,4NK4H@976|Bacteroidetes,2FNIK@200643|Bacteroidia	976|Bacteroidetes	CO	COG NOG24773 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin,Thioredoxin,Thioredoxin_8
TLS3_k127_225714_6	1122947.FR7_3437	2.333e-73	252.0	COG1051@1|root,COG1051@2|Bacteria,1U7WX@1239|Firmicutes,4H4D9@909932|Negativicutes	909932|Negativicutes	F	Hydrolase of X-linked nucleoside diphosphate N terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N
TLS3_k127_225714_1	1168289.AJKI01000030_gene1197	1.226e-125	410.0	COG0709@1|root,COG0709@2|Bacteria,4NI4R@976|Bacteroidetes,2FRGC@200643|Bacteroidia,3XIPW@558415|Marinilabiliaceae	976|Bacteroidetes	E	AIR synthase related protein, N-terminal domain	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
TLS3_k127_225714_9	1235798.C817_03415	2.258e-41	159.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,27V4U@189330|Dorea	186801|Clostridia	O	DsrE/DsrF-like family	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
TLS3_k127_225714_2	1279009.ADICEAN_01702	2.069e-121	393.0	COG4914@1|root,COG4914@2|Bacteria,4NJHM@976|Bacteroidetes,47TQW@768503|Cytophagia	976|Bacteroidetes	S	Nucleotidyl transferase of unknown function (DUF2204)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204,NTP_transf_5
TLS3_k127_225714_4	485918.Cpin_5533	4.148e-105	346.0	COG2129@1|root,COG2129@2|Bacteria,4NH2S@976|Bacteroidetes,1IQCI@117747|Sphingobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
TLS3_k127_225714_10	1168034.FH5T_10125	1.185e-27	124.0	COG0494@1|root,COG0494@2|Bacteria,4NSND@976|Bacteroidetes,2G0XF@200643|Bacteroidia	976|Bacteroidetes	L	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
TLS3_k127_225714_8	742726.HMPREF9448_01600	8.387e-45	167.0	COG0610@1|root,COG0610@2|Bacteria,4PKFE@976|Bacteroidetes,2FPFZ@200643|Bacteroidia,2322A@171551|Porphyromonadaceae	976|Bacteroidetes	V	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
TLS3_k127_225714_0	385682.AFSL01000002_gene1859	2.213e-130	419.0	COG2820@1|root,COG2820@2|Bacteria,4NESQ@976|Bacteroidetes,2FP2V@200643|Bacteroidia,3XJDX@558415|Marinilabiliaceae	976|Bacteroidetes	F	Phosphorylase superfamily	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
TLS3_k127_225714_3	694427.Palpr_0729	1.463e-112	372.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,2FNY6@200643|Bacteroidia,22W6C@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA polymerase III	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
TLS3_k127_225714_7	1168034.FH5T_21780	9.674e-56	200.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,2FM82@200643|Bacteroidia	976|Bacteroidetes	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
TLS3_k127_225714_5	909663.KI867150_gene372	7.89e-95	319.0	COG0444@1|root,COG0444@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
TLS3_k127_2276399_1	1408473.JHXO01000001_gene2036	1.501e-216	691.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,2FS4M@200643|Bacteroidia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_2276399_4	1123057.P872_21235	1.217e-78	271.0	COG0508@1|root,COG0508@2|Bacteria	2|Bacteria	C	S-acyltransferase activity	-	-	2.3.1.12,2.7.11.1,3.6.4.13	ko:K00627,ko:K03310,ko:K03578,ko:K12132	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko01001	2.A.25	-	-	2-oxoacid_dh,Biotin_lipoyl
TLS3_k127_2276399_5	1168034.FH5T_18280	4.607e-54	192.0	COG0614@1|root,COG0614@2|Bacteria,4NPTQ@976|Bacteroidetes	976|Bacteroidetes	P	GxxExxY protein	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
TLS3_k127_2276399_9	1046627.BZARG_2221	2.987e-40	155.0	COG2259@1|root,COG2259@2|Bacteria,4NSBJ@976|Bacteroidetes,1I2WV@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
TLS3_k127_2276399_2	1168034.FH5T_14690	1.427e-210	680.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes	976|Bacteroidetes	V	permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_2276399_8	1168034.FH5T_14695	2.689e-40	172.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes	976|Bacteroidetes	V	permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_2276399_7	1168289.AJKI01000001_gene3662	1.886e-40	152.0	COG0347@1|root,COG0347@2|Bacteria,4NQG9@976|Bacteroidetes	976|Bacteroidetes	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
TLS3_k127_2276399_3	869213.JCM21142_72630	1.69e-208	655.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,47K09@768503|Cytophagia	976|Bacteroidetes	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
TLS3_k127_2276399_6	927658.AJUM01000047_gene2997	2.129e-49	184.0	29A93@1|root,2ZX9Y@2|Bacteria,4NNMP@976|Bacteroidetes,2FN4N@200643|Bacteroidia	976|Bacteroidetes	S	non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
TLS3_k127_2276399_0	1408473.JHXO01000009_gene3324	7.35e-300	926.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,2FNDJ@200643|Bacteroidia	976|Bacteroidetes	E	Asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS3_k127_2276617_2	927658.AJUM01000034_gene290	1.892e-87	295.0	COG0731@1|root,COG0731@2|Bacteria,4NUA0@976|Bacteroidetes,2FUGW@200643|Bacteroidia,3XJHC@558415|Marinilabiliaceae	976|Bacteroidetes	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
TLS3_k127_2276617_3	694427.Palpr_2237	1.051e-56	212.0	COG0707@1|root,COG0707@2|Bacteria,4NFRJ@976|Bacteroidetes,2FXKG@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
TLS3_k127_2276617_5	869213.JCM21142_193	1.243e-26	117.0	COG0671@1|root,COG0671@2|Bacteria,4NUPJ@976|Bacteroidetes,47PT7@768503|Cytophagia	976|Bacteroidetes	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2276617_1	869213.JCM21142_192	3.047e-193	614.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,47KC2@768503|Cytophagia	976|Bacteroidetes	K	RNA polymerase, sigma-54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
TLS3_k127_2276617_0	742725.HMPREF9450_02306	1.407e-231	723.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,2FKYI@200643|Bacteroidia,22U8G@171550|Rikenellaceae	976|Bacteroidetes	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
TLS3_k127_2276617_4	927658.AJUM01000037_gene2026	6.592e-40	153.0	COG0589@1|root,COG0589@2|Bacteria,4NWVX@976|Bacteroidetes,2FW3E@200643|Bacteroidia,3XIUB@558415|Marinilabiliaceae	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_2307376_3	742727.HMPREF9447_04433	3.941e-14	74.0	COG3250@1|root,COG3250@2|Bacteria,4NF4T@976|Bacteroidetes,2FM5P@200643|Bacteroidia,4AMQD@815|Bacteroidaceae	976|Bacteroidetes	G	beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Bgal_small_N,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
TLS3_k127_2307376_0	1286170.RORB6_19410	6.881e-48	184.0	COG0726@1|root,COG0726@2|Bacteria,1MX6K@1224|Proteobacteria,1RYP1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Lipopolysaccharide biosynthesis protein	walW	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2307376_2	65393.PCC7424_5286	4.328e-16	91.0	COG0438@1|root,COG0438@2|Bacteria,1G1ED@1117|Cyanobacteria,3KGPQ@43988|Cyanothece	1117|Cyanobacteria	M	PFAM glycosyl transferase group 1	-	-	-	ko:K16703	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_2307376_1	1168034.FH5T_18660	1.716e-18	92.0	2EI0T@1|root,33BSA@2|Bacteria,4NYPN@976|Bacteroidetes,2FPS1@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2307939_3	1288963.ADIS_4388	1.57e-17	85.0	COG4948@1|root,COG4948@2|Bacteria,4NI24@976|Bacteroidetes,47N24@768503|Cytophagia	976|Bacteroidetes	M	mandelate racemase muconate lactonizing	-	-	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
TLS3_k127_2307939_2	880074.BARVI_06685	9.432e-37	144.0	COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,2FN46@200643|Bacteroidia,22Y3Y@171551|Porphyromonadaceae	976|Bacteroidetes	S	Glutamyl-tRNA amidotransferase	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
TLS3_k127_2307939_1	1237149.C900_05604	6.803e-89	309.0	COG0845@1|root,COG0845@2|Bacteria,4NGSC@976|Bacteroidetes,47TMZ@768503|Cytophagia	976|Bacteroidetes	M	HlyD membrane-fusion protein of T1SS	-	-	-	-	-	-	-	-	-	-	-	-	HlyD,HlyD_3,HlyD_D23
TLS3_k127_2307939_0	941824.TCEL_02329	1.209e-89	299.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,36EQY@31979|Clostridiaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_4
TLS3_k127_2316482_1	742817.HMPREF9449_00968	1.15e-232	731.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes,2FMWT@200643|Bacteroidia,22WZC@171551|Porphyromonadaceae	976|Bacteroidetes	E	Glutamate formiminotransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
TLS3_k127_2316482_0	929562.Emtol_3059	5.829e-256	817.0	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,4NDXS@976|Bacteroidetes,47YKE@768503|Cytophagia	976|Bacteroidetes	HP	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_2333838_6	1499967.BAYZ01000081_gene1041	1.582e-53	194.0	COG0476@1|root,COG0476@2|Bacteria,2NPRM@2323|unclassified Bacteria	2|Bacteria	H	ThiF family	thiF	-	2.7.7.73,2.7.7.80	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF,ThiS-like
TLS3_k127_2333838_0	1047013.AQSP01000096_gene2180	0.0	1047.0	COG2414@1|root,COG2414@2|Bacteria,2NNME@2323|unclassified Bacteria	2|Bacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
TLS3_k127_2333838_4	1408473.JHXO01000010_gene3618	2.419e-89	308.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes	976|Bacteroidetes	H	Molybdenum cofactor synthesis domain	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
TLS3_k127_2333838_8	1408473.JHXO01000010_gene3615	5.372e-45	169.0	COG0521@1|root,COG2258@1|root,COG0521@2|Bacteria,COG2258@2|Bacteria,4PNHR@976|Bacteroidetes	976|Bacteroidetes	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth,MoaC
TLS3_k127_2333838_3	869213.JCM21142_52254	9.483e-105	354.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,47UN2@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
TLS3_k127_2333838_2	1408473.JHXO01000006_gene1162	8.068e-153	495.0	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
TLS3_k127_2333838_1	1433126.BN938_1407	8.309e-166	529.0	COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,2FMD0@200643|Bacteroidia,22U18@171550|Rikenellaceae	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
TLS3_k127_2333838_5	1408473.JHXO01000006_gene1164	1.35e-60	216.0	COG2869@1|root,COG2869@2|Bacteria,4NF7A@976|Bacteroidetes,2FMQM@200643|Bacteroidia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
TLS3_k127_2333838_7	1211813.CAPH01000004_gene1217	5.666e-52	186.0	COG1347@1|root,COG1347@2|Bacteria,4NGD9@976|Bacteroidetes,2FN5K@200643|Bacteroidia,22U7J@171550|Rikenellaceae	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrD	-	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
TLS3_k127_2343718_5	1158294.JOMI01000007_gene483	1.144e-29	118.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,2FQNW@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_2343718_1	697282.Mettu_0542	1.348e-96	323.0	COG3861@1|root,COG3861@2|Bacteria,1RD6Y@1224|Proteobacteria,1S4FS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PRC
TLS3_k127_2343718_0	1168034.FH5T_06210	5.36e-129	421.0	COG0182@1|root,COG0182@2|Bacteria,4NETC@976|Bacteroidetes,2FR7K@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
TLS3_k127_2343718_3	866536.Belba_2773	1.094e-44	168.0	COG1309@1|root,COG1309@2|Bacteria,4NNNT@976|Bacteroidetes,47SG0@768503|Cytophagia	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	qacR	-	-	-	-	-	-	-	-	-	-	-	TetR_C_5,TetR_N
TLS3_k127_2343718_2	1408473.JHXO01000008_gene2866	8.389e-94	315.0	COG0682@1|root,COG0682@2|Bacteria,4NFP7@976|Bacteroidetes,2FMXU@200643|Bacteroidia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
TLS3_k127_2343718_4	760192.Halhy_3399	4.923e-30	127.0	COG0300@1|root,COG0300@2|Bacteria,4NKNE@976|Bacteroidetes,1J078@117747|Sphingobacteriia	976|Bacteroidetes	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
TLS3_k127_2376144_1	760192.Halhy_3515	8.38e-162	521.0	COG3386@1|root,COG3386@2|Bacteria,4NH7B@976|Bacteroidetes,1IP9W@117747|Sphingobacteriia	976|Bacteroidetes	G	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
TLS3_k127_2376144_2	762903.Pedsa_0806	2.05e-145	475.0	COG1073@1|root,COG1073@2|Bacteria,4NI6C@976|Bacteroidetes,1INXP@117747|Sphingobacteriia	976|Bacteroidetes	S	Acetyl xylan esterase	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
TLS3_k127_2376144_0	929713.NIASO_06940	3.822e-184	583.0	COG3386@1|root,COG3386@2|Bacteria,4NH7B@976|Bacteroidetes,1IP9W@117747|Sphingobacteriia	976|Bacteroidetes	G	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
TLS3_k127_2385256_0	1121904.ARBP01000002_gene7293	2.717e-212	684.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_2385256_1	1195236.CTER_1044	1.742e-176	575.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
TLS3_k127_2385256_2	1235803.C825_00947	1.783e-164	537.0	COG0006@1|root,COG0006@2|Bacteria,4NI1J@976|Bacteroidetes,2FNZP@200643|Bacteroidia,22WTJ@171551|Porphyromonadaceae	976|Bacteroidetes	E	peptidase M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
TLS3_k127_2385256_3	1408473.JHXO01000004_gene6	7.792e-98	334.0	COG5002@1|root,COG5002@2|Bacteria,4PMM9@976|Bacteroidetes	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
TLS3_k127_2390741_1	485918.Cpin_5378	2.184e-198	621.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,1IQZ2@117747|Sphingobacteriia	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
TLS3_k127_2390741_2	1506583.JQJY01000001_gene678	7.868e-100	330.0	COG0266@1|root,COG0266@2|Bacteria,4NH8P@976|Bacteroidetes,1HZMI@117743|Flavobacteriia,2NUNE@237|Flavobacterium	976|Bacteroidetes	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH
TLS3_k127_2390741_0	886379.AEWI01000024_gene322	1.288e-292	905.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,2FMTR@200643|Bacteroidia,3XIM3@558415|Marinilabiliaceae	976|Bacteroidetes	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_2390741_4	1168034.FH5T_06775	6.387e-52	190.0	COG1917@1|root,COG1917@2|Bacteria,4NMER@976|Bacteroidetes,2G0DI@200643|Bacteroidia	976|Bacteroidetes	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
TLS3_k127_2390741_3	203275.BFO_0303	1.025e-63	228.0	COG1235@1|root,COG1235@2|Bacteria,4NDVI@976|Bacteroidetes,2FN8Y@200643|Bacteroidia,22WMP@171551|Porphyromonadaceae	976|Bacteroidetes	S	metallo-beta-lactamase	vicX	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
TLS3_k127_2390741_5	1121878.AUGL01000023_gene3538	2.53e-32	134.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,1RNZC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Gram-negative-bacterium-type cell wall biogenesis	ycbC	GO:0000270,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0030203,GO:0031224,GO:0042546,GO:0043164,GO:0043170,GO:0044085,GO:0044425,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901564	-	-	-	-	-	-	-	-	-	-	DUF218
TLS3_k127_2392171_4	7719.XP_002127006.1	0.0003084	50.0	COG0484@1|root,KOG0624@2759|Eukaryota,38BUQ@33154|Opisthokonta,3BATC@33208|Metazoa,3CTQ2@33213|Bilateria,4848C@7711|Chordata	33208|Metazoa	O	positive regulation of translation initiation in response to endoplasmic reticulum stress	DNAJC3	GO:0000323,GO:0001775,GO:0001932,GO:0001933,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0004857,GO:0004860,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0005790,GO:0005829,GO:0006417,GO:0006446,GO:0006464,GO:0006469,GO:0006508,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006955,GO:0006986,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010563,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010941,GO:0012505,GO:0016192,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019538,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0023052,GO:0030141,GO:0030163,GO:0030234,GO:0030968,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031399,GO:0031400,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032056,GO:0032058,GO:0032268,GO:0032269,GO:0032270,GO:0032940,GO:0033554,GO:0033673,GO:0034248,GO:0034250,GO:0034620,GO:0034774,GO:0034976,GO:0035578,GO:0035966,GO:0035967,GO:0036211,GO:0036230,GO:0036490,GO:0036491,GO:0036493,GO:0036494,GO:0036498,GO:0042119,GO:0042221,GO:0042325,GO:0042326,GO:0042582,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043412,GO:0043549,GO:0043555,GO:0043558,GO:0043687,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045727,GO:0045859,GO:0045936,GO:0045948,GO:0046903,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051087,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051338,GO:0051348,GO:0051603,GO:0051716,GO:0051787,GO:0060205,GO:0060255,GO:0060548,GO:0065007,GO:0065009,GO:0070013,GO:0070417,GO:0070887,GO:0071310,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0097708,GO:0098772,GO:0099503,GO:1901564,GO:1901565,GO:1901575,GO:1903573,GO:1903912,GO:1905897,GO:2000112	-	ko:K09523	ko04141,ko05164,map04141,map05164	-	-	-	ko00000,ko00001,ko03110	-	-	-	DnaJ,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
TLS3_k127_2392171_1	717605.Theco_3925	2.998e-92	306.0	COG1225@1|root,COG1225@2|Bacteria,1V058@1239|Firmicutes,4HE2H@91061|Bacilli,26T9E@186822|Paenibacillaceae	91061|Bacilli	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
TLS3_k127_2392171_2	1174528.JH992898_gene5207	1.268e-63	224.0	COG0259@1|root,COG0259@2|Bacteria,1G0HC@1117|Cyanobacteria,1JHDR@1189|Stigonemataceae	1117|Cyanobacteria	H	Pfam:PNPOx_C	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.pdxH	PNP_phzG_C,Putative_PNPOx
TLS3_k127_2392171_0	760192.Halhy_5983	2.938e-224	705.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1IPND@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,Glyco_hydro_20,Glyco_hydro_20b
TLS3_k127_2392171_3	1121904.ARBP01000001_gene5830	7.969e-16	80.0	COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,47NCY@768503|Cytophagia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
TLS3_k127_2392182_0	1121898.Q766_10045	8.004e-185	594.0	COG3292@1|root,COG4935@1|root,COG5337@1|root,COG3292@2|Bacteria,COG4935@2|Bacteria,COG5337@2|Bacteria,4NH8G@976|Bacteroidetes,1HYKE@117743|Flavobacteriia,2NWXZ@237|Flavobacterium	976|Bacteroidetes	MO	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
TLS3_k127_240224_1	98439.AJLL01000023_gene852	2.084e-10	61.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1G1Q1@1117|Cyanobacteria	1117|Cyanobacteria	EU	PFAM Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
TLS3_k127_240224_0	694427.Palpr_1465	3.57e-303	944.0	COG0370@1|root,COG1918@1|root,COG0370@2|Bacteria,COG1918@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia,22VWF@171551|Porphyromonadaceae	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
TLS3_k127_241261_1	1168034.FH5T_08455	1.988e-64	240.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,2FPZX@200643|Bacteroidia	976|Bacteroidetes	KT	PspC domain protein	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
TLS3_k127_241261_3	385682.AFSL01000105_gene133	6.493e-50	179.0	COG1695@1|root,COG1695@2|Bacteria,4NSI4@976|Bacteroidetes,2FTF6@200643|Bacteroidia,3XK3G@558415|Marinilabiliaceae	976|Bacteroidetes	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
TLS3_k127_241261_4	1168034.FH5T_08455	1.975e-47	177.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,2FPZX@200643|Bacteroidia	976|Bacteroidetes	KT	PspC domain protein	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
TLS3_k127_241261_0	1408473.JHXO01000008_gene2756	6.562e-101	338.0	COG0673@1|root,COG0673@2|Bacteria,4NE07@976|Bacteroidetes,2FNUN@200643|Bacteroidia	976|Bacteroidetes	H	Oxidoreductase NAD-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_241261_2	1408473.JHXO01000008_gene2875	2.357e-53	197.0	COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,2FMIT@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TLS3_k127_2413402_1	1433126.BN938_1607	9.107e-222	696.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,2FMKX@200643|Bacteroidia,22U22@171550|Rikenellaceae	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
TLS3_k127_2413402_2	1408473.JHXO01000005_gene1651	8.167e-218	693.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,2FMT4@200643|Bacteroidia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
TLS3_k127_2413402_4	694427.Palpr_1037	7.136e-85	285.0	COG0053@1|root,COG0053@2|Bacteria,4NJRM@976|Bacteroidetes	976|Bacteroidetes	P	PFAM Cation efflux	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
TLS3_k127_2413402_3	457570.Nther_2813	3.089e-206	663.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia	186801|Clostridia	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
TLS3_k127_2413402_5	1408813.AYMG01000012_gene875	4.724e-46	170.0	COG3607@1|root,COG3607@2|Bacteria,4NSG5@976|Bacteroidetes	976|Bacteroidetes	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS3_k127_2413402_0	886379.AEWI01000042_gene3360	0.0	1056.0	COG1523@1|root,COG1523@2|Bacteria,4NIH2@976|Bacteroidetes,2FKZS@200643|Bacteroidia,3XISJ@558415|Marinilabiliaceae	976|Bacteroidetes	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
TLS3_k127_2424119_6	1506583.JQJY01000009_gene954	6.55e-29	128.0	28M3Z@1|root,2ZAI2@2|Bacteria,4NIUF@976|Bacteroidetes,1HYP1@117743|Flavobacteriia,2NU0Q@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2424119_8	635013.TherJR_0931	4.227e-05	56.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,2606T@186807|Peptococcaceae	186801|Clostridia	P	pyridine nucleotide-disulphide oxidoreductase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
TLS3_k127_2424119_7	1293054.HSACCH_01928	1.134e-25	123.0	COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes,24AGI@186801|Clostridia	186801|Clostridia	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
TLS3_k127_2424119_4	694427.Palpr_1347	5.996e-64	227.0	2AINN@1|root,31954@2|Bacteria,4P6MS@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
TLS3_k127_2424119_2	1123248.KB893334_gene2777	6.949e-123	403.0	COG2972@1|root,COG2972@2|Bacteria,4NRI4@976|Bacteroidetes,1IV8I@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_2424119_5	746697.Aeqsu_0432	3.61e-60	215.0	COG3279@1|root,COG3279@2|Bacteria,4NIJQ@976|Bacteroidetes,1IIN1@117743|Flavobacteriia	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_2424119_1	1408254.T458_09100	3.452e-137	443.0	COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,26QXS@186822|Paenibacillaceae	91061|Bacilli	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
TLS3_k127_2424119_0	700598.Niako_1910	1.942e-143	464.0	COG0620@1|root,COG0620@2|Bacteria,4NJAH@976|Bacteroidetes,1IZXY@117747|Sphingobacteriia	976|Bacteroidetes	E	COGs COG0620 Methionine synthase II (cobalamin-independent)	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
TLS3_k127_2424119_3	797299.HALLA_10825	1.509e-109	384.0	COG0642@1|root,arCOG02352@1|root,arCOG06712@1|root,arCOG02352@2157|Archaea,arCOG02358@2157|Archaea,arCOG06192@2157|Archaea,arCOG06712@2157|Archaea,2Y7KG@28890|Euryarchaeota	28890|Euryarchaeota	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
TLS3_k127_247380_3	927658.AJUM01000037_gene2070	1.311e-82	283.0	COG0168@1|root,COG0168@2|Bacteria,4NGMF@976|Bacteroidetes,2FNQZ@200643|Bacteroidia,3XIYR@558415|Marinilabiliaceae	976|Bacteroidetes	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
TLS3_k127_247380_0	742767.HMPREF9456_02771	6.602e-94	312.0	COG0745@1|root,COG0745@2|Bacteria,4NIQC@976|Bacteroidetes,2G2Z1@200643|Bacteroidia,22ZCV@171551|Porphyromonadaceae	976|Bacteroidetes	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_247380_1	694427.Palpr_1547	4.431e-93	317.0	COG0642@1|root,COG2205@2|Bacteria,4PNTS@976|Bacteroidetes	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4
TLS3_k127_247380_4	1168034.FH5T_20715	3.499e-50	186.0	2AU2S@1|root,31JP5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_247380_2	1304883.KI912532_gene3044	5.861e-85	288.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,2KVRY@206389|Rhodocyclales	206389|Rhodocyclales	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
TLS3_k127_2498756_4	485913.Krac_10280	1.563e-12	70.0	COG0596@1|root,COG0596@2|Bacteria,2G6VQ@200795|Chloroflexi	2|Bacteria	S	PFAM alpha beta hydrolase fold	MA20_20400	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Abhydrolase_6
TLS3_k127_2498756_3	1189612.A33Q_2654	1.829e-29	125.0	COG4704@1|root,COG4704@2|Bacteria,4NUMP@976|Bacteroidetes,47SYD@768503|Cytophagia	976|Bacteroidetes	S	Fibrobacter succinogenes major domain (Fib_succ_major)	-	-	-	-	-	-	-	-	-	-	-	-	Fib_succ_major,Mfa_like_1
TLS3_k127_2498756_2	583355.Caka_0705	6.154e-148	480.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_2498756_0	1121887.AUDK01000010_gene1342	1.136e-248	792.0	COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,1HXYF@117743|Flavobacteriia,2NVHB@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
TLS3_k127_2498756_1	56780.SYN_00005	8.095e-157	501.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,42PVB@68525|delta/epsilon subdivisions,2WIMK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
TLS3_k127_2507659_1	742727.HMPREF9447_03458	0.0007427	42.0	COG2067@1|root,COG2067@2|Bacteria,4NKM1@976|Bacteroidetes,2FPD4@200643|Bacteroidia,4AMHD@815|Bacteroidaceae	976|Bacteroidetes	I	COG COG2067 Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	OMP_b-brl
TLS3_k127_2507659_0	411477.PARMER_03655	0.0	1195.0	COG3250@1|root,COG3250@2|Bacteria,4NIBS@976|Bacteroidetes,2FPZ2@200643|Bacteroidia,22ZBT@171551|Porphyromonadaceae	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
TLS3_k127_2518460_0	926549.KI421517_gene2412	3.101e-123	411.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_2518460_3	1121904.ARBP01000030_gene1963	3.242e-39	149.0	COG1695@1|root,COG1695@2|Bacteria,4NUDG@976|Bacteroidetes	976|Bacteroidetes	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_2518460_1	1108045.GORHZ_154_00260	2.031e-120	396.0	COG2072@1|root,COG2072@2|Bacteria,2GM3S@201174|Actinobacteria,4GGGG@85026|Gordoniaceae	201174|Actinobacteria	P	Flavin-binding monooxygenase-like	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
TLS3_k127_2518460_2	266779.Meso_2458	2.961e-75	261.0	COG0500@1|root,COG2267@1|root,COG2226@2|Bacteria,COG2267@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,43PQD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
TLS3_k127_2529552_2	1121875.KB907548_gene1563	4.109e-26	121.0	COG1413@1|root,COG1413@2|Bacteria,4NGY4@976|Bacteroidetes,1II9U@117743|Flavobacteriia	976|Bacteroidetes	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
TLS3_k127_2529552_0	1168034.FH5T_09840	7.168e-161	520.0	COG1215@1|root,COG1215@2|Bacteria,4NH18@976|Bacteroidetes,2G2V7@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,Sulfatase
TLS3_k127_2529552_1	1453500.AT05_04770	1.883e-156	527.0	COG0457@1|root,COG0457@2|Bacteria	1453500.AT05_04770|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2582203_0	1047013.AQSP01000140_gene2494	2.439e-160	516.0	COG2234@1|root,COG2234@2|Bacteria,2NRCG@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
TLS3_k127_2582203_2	421072.IO89_16395	5.23e-36	142.0	COG2010@1|root,COG2010@2|Bacteria,4NSE3@976|Bacteroidetes,1I28K@117743|Flavobacteriia,3HIY0@358033|Chryseobacterium	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
TLS3_k127_2582203_1	1121094.KB894644_gene2075	1.865e-51	198.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,2G2V9@200643|Bacteroidia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
TLS3_k127_259009_1	929704.Myrod_0500	5.394e-230	730.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,4NEK3@976|Bacteroidetes,1HXIK@117743|Flavobacteriia,47HXK@76831|Myroides	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8
TLS3_k127_259009_0	886379.AEWI01000042_gene3359	1.833e-316	998.0	COG1640@1|root,COG3280@1|root,COG1640@2|Bacteria,COG3280@2|Bacteria,4NF7Z@976|Bacteroidetes,2FMBZ@200643|Bacteroidia,3XJCM@558415|Marinilabiliaceae	976|Bacteroidetes	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Alpha-amylase,Glyco_hydro_77
TLS3_k127_2600501_0	1121104.AQXH01000004_gene58	3.727e-220	702.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1IUTX@117747|Sphingobacteriia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
TLS3_k127_2614436_5	763034.HMPREF9446_02070	1.725e-37	144.0	COG0838@1|root,COG0838@2|Bacteria,4NQET@976|Bacteroidetes,2FTGA@200643|Bacteroidia,4AQZM@815|Bacteroidaceae	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
TLS3_k127_2614436_2	1121129.KB903359_gene1193	6.568e-79	268.0	COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,2FMK8@200643|Bacteroidia,22WBX@171551|Porphyromonadaceae	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
TLS3_k127_2614436_4	1121875.KB907547_gene3142	1.313e-43	163.0	COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,1I1PJ@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
TLS3_k127_2614436_0	313603.FB2170_07949	1.553e-162	520.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1HZMG@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
TLS3_k127_2614436_1	742725.HMPREF9450_00513	2.865e-156	499.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,2FNVC@200643|Bacteroidia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
TLS3_k127_2614436_3	1121875.KB907547_gene3145	3.143e-58	205.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,1I6VR@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
TLS3_k127_2632249_0	929556.Solca_2463	1.68e-151	490.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1INSD@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_2632249_1	880074.BARVI_05630	2.213e-34	143.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,2FN49@200643|Bacteroidia,22XCR@171551|Porphyromonadaceae	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_2637286_1	1168289.AJKI01000011_gene506	9.23e-67	229.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,2FNA0@200643|Bacteroidia,3XIWS@558415|Marinilabiliaceae	976|Bacteroidetes	P	Iron/manganese superoxide dismutases, alpha-hairpin domain	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
TLS3_k127_2637286_0	498761.HM1_3019	5.369e-75	256.0	COG0778@1|root,COG0778@2|Bacteria,1V4ZI@1239|Firmicutes,24BD0@186801|Clostridia	186801|Clostridia	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
TLS3_k127_2637286_2	1408473.JHXO01000006_gene1116	1.837e-22	104.0	2DPHD@1|root,33234@2|Bacteria,4NV1C@976|Bacteroidetes,2FV5V@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2646956_3	694427.Palpr_1019	9.866e-15	75.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,2FMQN@200643|Bacteroidia,22X6K@171551|Porphyromonadaceae	976|Bacteroidetes	MP	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HMA,HlyD_D23
TLS3_k127_2646956_1	694427.Palpr_1018	3.464e-119	399.0	COG1538@1|root,COG1538@2|Bacteria,4NDXW@976|Bacteroidetes,2FN4C@200643|Bacteroidia,22XHC@171551|Porphyromonadaceae	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_2646956_0	694427.Palpr_1017	0.0	2014.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,2G0EK@200643|Bacteroidia	976|Bacteroidetes	V	AcrB/AcrD/AcrF family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
TLS3_k127_2646956_2	694427.Palpr_1016	1.956e-26	113.0	COG2608@1|root,COG2608@2|Bacteria,4NUTQ@976|Bacteroidetes,2FV9V@200643|Bacteroidia	976|Bacteroidetes	P	Heavy-metal-associated domain	-	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA
TLS3_k127_2693130_4	1121887.AUDK01000018_gene3261	6.021e-41	158.0	COG1309@1|root,COG1309@2|Bacteria,4NIBT@976|Bacteroidetes,1HZ1F@117743|Flavobacteriia,2NSK7@237|Flavobacterium	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_2693130_2	1453498.LG45_05045	1.103e-79	282.0	COG1538@1|root,COG1538@2|Bacteria,4NFSW@976|Bacteroidetes,1HXCD@117743|Flavobacteriia,2NSVK@237|Flavobacterium	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_2693130_3	1168034.FH5T_02825	1.067e-75	263.0	COG1566@1|root,COG1566@2|Bacteria,4PKPZ@976|Bacteroidetes,2G0E5@200643|Bacteroidia	976|Bacteroidetes	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS3_k127_2693130_0	319225.Plut_1081	6.051e-113	373.0	COG1131@1|root,COG1131@2|Bacteria,1FDMR@1090|Chlorobi	1090|Chlorobi	V	PFAM ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
TLS3_k127_2693130_1	1086011.HJ01_02194	9.832e-98	326.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HZ83@117743|Flavobacteriia,2P00V@237|Flavobacterium	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_2693130_5	1086011.HJ01_02193	7.318e-29	118.0	COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes,1HX8Q@117743|Flavobacteriia,2NT6W@237|Flavobacterium	976|Bacteroidetes	U	ABC-2 type transporter	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
TLS3_k127_2710265_0	763034.HMPREF9446_01225	5.806e-194	614.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,2FNMZ@200643|Bacteroidia,4ANUP@815|Bacteroidaceae	976|Bacteroidetes	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
TLS3_k127_2710265_1	1313421.JHBV01000016_gene5713	1.594e-58	212.0	COG2374@1|root,COG2374@2|Bacteria,4NEHG@976|Bacteroidetes	976|Bacteroidetes	S	Endonuclease exonuclease phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_27272_1	1123290.AUDQ01000002_gene2372	6.349e-28	116.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,4HAWW@91061|Bacilli,26DKE@186818|Planococcaceae	91061|Bacilli	EH	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction	dat	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_27272_0	1408473.JHXO01000011_gene2976	7.842e-277	861.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,2FMXC@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
TLS3_k127_27272_2	262316.MAP_3760c	3.375e-05	50.0	COG0500@1|root,COG2226@2|Bacteria,2GJUF@201174|Actinobacteria,236M1@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Catalyzes the methylation of the lipid moiety of the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycoserosates to form phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL)	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_2728330_2	742766.HMPREF9455_03640	2.586e-44	163.0	COG0159@1|root,COG0159@2|Bacteria,4NE21@976|Bacteroidetes,2FPFP@200643|Bacteroidia,22W9T@171551|Porphyromonadaceae	976|Bacteroidetes	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
TLS3_k127_2728330_0	307480.IW16_10525	8.49e-173	549.0	COG0133@1|root,COG0133@2|Bacteria,4NDWP@976|Bacteroidetes,1HXYK@117743|Flavobacteriia,3ZQC4@59732|Chryseobacterium	976|Bacteroidetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_2728330_3	927658.AJUM01000037_gene2408	1.862e-43	167.0	COG0135@1|root,COG0135@2|Bacteria,4NNQ1@976|Bacteroidetes,2FPJD@200643|Bacteroidia,3XJYU@558415|Marinilabiliaceae	976|Bacteroidetes	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
TLS3_k127_2728330_1	1122176.KB903554_gene3930	5.842e-66	233.0	COG0134@1|root,COG0134@2|Bacteria,4NFJT@976|Bacteroidetes,1IPVG@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
TLS3_k127_2754706_1	1408473.JHXO01000006_gene1198	7.865e-38	149.0	COG4589@1|root,COG4589@2|Bacteria,4NIPM@976|Bacteroidetes,2FMKC@200643|Bacteroidia	976|Bacteroidetes	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
TLS3_k127_2754706_0	1168034.FH5T_09665	3.083e-265	834.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,2FNEA@200643|Bacteroidia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
TLS3_k127_2754706_2	760192.Halhy_3581	6.65e-26	110.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,1ISS0@117747|Sphingobacteriia	976|Bacteroidetes	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
TLS3_k127_275904_1	755732.Fluta_1591	5.587e-82	285.0	COG0438@1|root,COG0438@2|Bacteria,4NH7K@976|Bacteroidetes,1I0D7@117743|Flavobacteriia,2PAGP@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_275904_0	1408473.JHXO01000007_gene866	1.147e-218	688.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase, NAD-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_275904_2	1124780.ANNU01000005_gene2500	2.221e-61	215.0	COG3263@1|root,COG3263@2|Bacteria,4NFNS@976|Bacteroidetes,47P2K@768503|Cytophagia	976|Bacteroidetes	P	TrkA-C domain	cvrA	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
TLS3_k127_2784359_0	886379.AEWI01000005_gene961	3.501e-143	461.0	COG1271@1|root,COG1271@2|Bacteria,4NG7U@976|Bacteroidetes,2FMV6@200643|Bacteroidia,3XJ3B@558415|Marinilabiliaceae	976|Bacteroidetes	C	Cytochrome bd terminal oxidase subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
TLS3_k127_2784359_6	1265505.ATUG01000003_gene734	2.074e-10	66.0	2E3BY@1|root,32YBB@2|Bacteria,1NDZS@1224|Proteobacteria,42X6C@68525|delta/epsilon subdivisions,2WSF7@28221|Deltaproteobacteria,2MPAM@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4492)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4492
TLS3_k127_2784359_2	1168034.FH5T_05150	1.342e-83	291.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,2FN2B@200643|Bacteroidia	976|Bacteroidetes	F	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS3_k127_2784359_4	1286632.P278_17900	4.322e-32	129.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I382@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
TLS3_k127_2784359_1	194439.CT2285	4.22e-143	466.0	COG0426@1|root,COG0426@2|Bacteria,1FDX4@1090|Chlorobi	1090|Chlorobi	C	PFAM beta-lactamase domain protein	-	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_1,Lactamase_B
TLS3_k127_2784359_3	926549.KI421517_gene845	3.884e-70	244.0	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,47MWN@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
TLS3_k127_2784359_5	525373.HMPREF0766_10950	2.294e-14	73.0	COG0575@1|root,COG0575@2|Bacteria,4PPXI@976|Bacteroidetes,1J13D@117747|Sphingobacteriia	976|Bacteroidetes	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
TLS3_k127_2804978_6	869213.JCM21142_134722	2.091e-79	273.0	COG0569@1|root,COG0569@2|Bacteria,4NIX8@976|Bacteroidetes,47YH2@768503|Cytophagia	976|Bacteroidetes	P	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2
TLS3_k127_2804978_4	1121481.AUAS01000005_gene1900	8.047e-167	531.0	COG2730@1|root,COG2730@2|Bacteria,4NGAC@976|Bacteroidetes,47MSS@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
TLS3_k127_2804978_5	471854.Dfer_1232	3.743e-91	308.0	COG1082@1|root,COG1082@2|Bacteria,4NIWS@976|Bacteroidetes,47K4W@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
TLS3_k127_2804978_1	929556.Solca_3964	1.477e-196	632.0	COG1368@1|root,COG1368@2|Bacteria,4NIAA@976|Bacteroidetes,1IQ3M@117747|Sphingobacteriia	976|Bacteroidetes	M	sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TLS3_k127_2804978_0	927658.AJUM01000044_gene623	0.0	1029.0	COG1166@1|root,COG1166@2|Bacteria,4PKX0@976|Bacteroidetes,2FMN2@200643|Bacteroidia,3XINI@558415|Marinilabiliaceae	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
TLS3_k127_2804978_8	452637.Oter_1159	5.597e-29	117.0	COG3867@1|root,COG3867@2|Bacteria,46VSS@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM glycosyl hydrolase 53 domain protein	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
TLS3_k127_2804978_3	1047013.AQSP01000089_gene1176	6.71e-178	572.0	COG2866@1|root,COG2866@2|Bacteria,2NQT6@2323|unclassified Bacteria	2|Bacteria	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
TLS3_k127_2804978_9	1408473.JHXO01000006_gene1325	9.037e-26	107.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,2FYPS@200643|Bacteroidia	976|Bacteroidetes	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
TLS3_k127_2804978_7	694427.Palpr_2271	5.407e-63	224.0	COG0363@1|root,COG0363@2|Bacteria,4NGB9@976|Bacteroidetes,2FNZF@200643|Bacteroidia,22XT3@171551|Porphyromonadaceae	976|Bacteroidetes	G	6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
TLS3_k127_2804978_2	945713.IALB_1968	6.743e-184	583.0	COG0364@1|root,COG0364@2|Bacteria	2|Bacteria	G	glucose-6-phosphate dehydrogenase activity	zwf	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iIT341.HP1101	G6PD_C,G6PD_N
TLS3_k127_2824747_0	584708.Apau_0678	1.051e-201	636.0	COG1012@1|root,COG1012@2|Bacteria,3TARH@508458|Synergistetes	508458|Synergistetes	C	1-pyrroline-5-carboxylate dehydrogenase	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
TLS3_k127_2824747_2	1123058.KB894262_gene1388	3.632e-50	190.0	COG1597@1|root,COG1597@2|Bacteria,4NJWB@976|Bacteroidetes,1HZF4@117743|Flavobacteriia	976|Bacteroidetes	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
TLS3_k127_2824747_1	1123248.KB893315_gene2998	1.861e-152	494.0	COG3391@1|root,COG3391@2|Bacteria,4NER2@976|Bacteroidetes,1IQ4S@117747|Sphingobacteriia	976|Bacteroidetes	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
TLS3_k127_2837252_1	1408473.JHXO01000008_gene2739	4.048e-180	568.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFBK@976|Bacteroidetes,2FM6S@200643|Bacteroidia	976|Bacteroidetes	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
TLS3_k127_2837252_2	1185876.BN8_00865	1.859e-103	348.0	28N78@1|root,2ZBBY@2|Bacteria,4NGF9@976|Bacteroidetes,47X4G@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4932
TLS3_k127_2837252_0	1349822.NSB1T_12740	1.772e-205	647.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,2FMW7@200643|Bacteroidia,22VV9@171551|Porphyromonadaceae	976|Bacteroidetes	S	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_2850443_4	1408473.JHXO01000001_gene2030	2.091e-09	60.0	28NPZ@1|root,2ZBPQ@2|Bacteria,4NN3K@976|Bacteroidetes,2FPEH@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_2850443_3	926549.KI421517_gene485	1.107e-19	95.0	COG0806@1|root,COG0806@2|Bacteria,4NQF0@976|Bacteroidetes,47QUB@768503|Cytophagia	976|Bacteroidetes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
TLS3_k127_2850443_2	1408473.JHXO01000010_gene3603	1.755e-61	216.0	COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
TLS3_k127_2850443_1	411477.PARMER_02835	1.643e-67	239.0	COG1216@1|root,COG1216@2|Bacteria,4NRTB@976|Bacteroidetes	976|Bacteroidetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2850443_0	1408473.JHXO01000010_gene3601	3.633e-193	612.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,2FNND@200643|Bacteroidia	976|Bacteroidetes	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
TLS3_k127_28841_2	1288826.MSNKSG1_14212	3.21e-38	150.0	2DE7S@1|root,2ZKW3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_28841_0	665956.HMPREF1032_03825	2.837e-88	311.0	COG1082@1|root,COG1501@1|root,COG1082@2|Bacteria,COG1501@2|Bacteria,1UFEU@1239|Firmicutes,24FG8@186801|Clostridia,3WI2N@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl-hydrolase 97 C-terminal, oligomerisation	-	-	-	-	-	-	-	-	-	-	-	-	CBM_35,GH97_C,GH97_N,Glyco_hydro_97,Laminin_G_3
TLS3_k127_2913714_2	886379.AEWI01000007_gene781	2.773e-198	632.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,4NFA9@976|Bacteroidetes,2FPAX@200643|Bacteroidia,3XJHG@558415|Marinilabiliaceae	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PQQ,PQQ_2,PQQ_3
TLS3_k127_2913714_5	385682.AFSL01000008_gene2627	6.021e-85	289.0	COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,2FNFM@200643|Bacteroidia,3XJCE@558415|Marinilabiliaceae	976|Bacteroidetes	G	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
TLS3_k127_2913714_3	385682.AFSL01000008_gene2626	1.073e-120	394.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,2FNYH@200643|Bacteroidia,3XIQY@558415|Marinilabiliaceae	976|Bacteroidetes	S	SIS domain	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS
TLS3_k127_2913714_4	385682.AFSL01000008_gene2625	3.801e-99	328.0	COG2186@1|root,COG2186@2|Bacteria,4NEUP@976|Bacteroidetes,2FVTP@200643|Bacteroidia,3XIRV@558415|Marinilabiliaceae	976|Bacteroidetes	K	FCD	pdhR	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
TLS3_k127_2913714_0	926549.KI421517_gene119	3.192e-301	953.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,47M0A@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
TLS3_k127_2913714_1	1123008.KB905696_gene2962	9.312e-237	744.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,2FMFZ@200643|Bacteroidia,22XG3@171551|Porphyromonadaceae	976|Bacteroidetes	E	Psort location CytoplasmicMembrane, score 10.00	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
TLS3_k127_2916438_1	1121895.Q765_06135	1.596e-26	118.0	2C79K@1|root,33JYK@2|Bacteria,4NXTR@976|Bacteroidetes,1ID7H@117743|Flavobacteriia,2NXKT@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2916438_0	886379.AEWI01000013_gene2112	2.476e-248	772.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,2FM4G@200643|Bacteroidia,3XJSP@558415|Marinilabiliaceae	976|Bacteroidetes	I	Carboxyl transferase domain	mmdA	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
TLS3_k127_2950930_13	1433126.BN938_2016	4.042e-33	130.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,2FM2I@200643|Bacteroidia,22UAD@171550|Rikenellaceae	976|Bacteroidetes	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
TLS3_k127_2950930_3	886379.AEWI01000007_gene820	7.614e-209	660.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,2FN3G@200643|Bacteroidia,3XJ3E@558415|Marinilabiliaceae	976|Bacteroidetes	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
TLS3_k127_2950930_8	880526.KE386488_gene518	6.726e-105	354.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,2FX5C@200643|Bacteroidia,22VRW@171550|Rikenellaceae	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_2950930_9	869213.JCM21142_339	1.093e-89	303.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,47KWT@768503|Cytophagia	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
TLS3_k127_2950930_2	927658.AJUM01000037_gene2129	2.256e-244	789.0	COG1131@1|root,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,2FRF1@200643|Bacteroidia,3XIKU@558415|Marinilabiliaceae	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran
TLS3_k127_2950930_11	1168289.AJKI01000011_gene642	6.052e-48	182.0	29N3N@1|root,33PNI@2|Bacteria,4P1TW@976|Bacteroidetes,2G20D@200643|Bacteroidia,3XIQT@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2950930_7	1408473.JHXO01000010_gene3778	7.374e-128	419.0	COG1168@1|root,COG1168@2|Bacteria,4NETH@976|Bacteroidetes,2FMIZ@200643|Bacteroidia	976|Bacteroidetes	E	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_2950930_5	886379.AEWI01000005_gene958	7.79e-172	545.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,2FMSR@200643|Bacteroidia,3XIIH@558415|Marinilabiliaceae	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
TLS3_k127_2950930_6	869213.JCM21142_93626	2.318e-139	456.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,47JA3@768503|Cytophagia	976|Bacteroidetes	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
TLS3_k127_2950930_4	688269.Theth_1539	3.406e-186	589.0	COG0137@1|root,COG0137@2|Bacteria	2|Bacteria	E	argininosuccinate synthase activity	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.argG,iSB619.SA_RS04675	Arginosuc_synth
TLS3_k127_2950930_14	1349822.NSB1T_03000	1.377e-26	115.0	COG1438@1|root,COG1438@2|Bacteria,4NSSS@976|Bacteroidetes,2FR3Q@200643|Bacteroidia,22YDN@171551|Porphyromonadaceae	976|Bacteroidetes	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
TLS3_k127_2950930_0	927658.AJUM01000037_gene2330	0.0	1648.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,2FMKD@200643|Bacteroidia,3XIQ0@558415|Marinilabiliaceae	976|Bacteroidetes	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
TLS3_k127_2950930_12	1163409.UUA_16398	6.211e-39	150.0	COG0454@1|root,COG0456@2|Bacteria,1RJ1K@1224|Proteobacteria,1S6RV@1236|Gammaproteobacteria,1X6U1@135614|Xanthomonadales	135614|Xanthomonadales	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_2950930_10	700598.Niako_6492	5.391e-54	203.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,1IPRP@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_2950930_1	886379.AEWI01000023_gene8	0.0	1070.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,2FMBR@200643|Bacteroidia,3XJ41@558415|Marinilabiliaceae	976|Bacteroidetes	L	RQC	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
TLS3_k127_2953782_3	1168034.FH5T_17245	4.002e-76	277.0	28KYZ@1|root,2ZAEB@2|Bacteria,4NHBZ@976|Bacteroidetes,2FP4X@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2953782_1	1168034.FH5T_17240	5.121e-139	458.0	COG0823@1|root,COG0823@2|Bacteria,4NGH4@976|Bacteroidetes,2FN8G@200643|Bacteroidia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_2953782_0	1408473.JHXO01000001_gene1962	2.175e-144	464.0	COG0667@1|root,COG0667@2|Bacteria,4PPAM@976|Bacteroidetes,2G14T@200643|Bacteroidia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_2953782_5	6087.XP_002170883.2	3.975e-26	123.0	COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3BJ5Q@33208|Metazoa	33208|Metazoa	M	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
TLS3_k127_2953782_2	1408473.JHXO01000007_gene847	7.437e-117	391.0	COG1680@1|root,COG1680@2|Bacteria,4NF42@976|Bacteroidetes,2FQ3Z@200643|Bacteroidia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_2953782_4	504472.Slin_1581	3.827e-53	195.0	COG2135@1|root,COG2135@2|Bacteria,4NI3T@976|Bacteroidetes,47XPZ@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the SOS response-associated peptidase family	yoqW	-	-	-	-	-	-	-	-	-	-	-	SRAP
TLS3_k127_2960742_0	927658.AJUM01000034_gene179	2.502e-192	607.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,3XJMS@558415|Marinilabiliaceae	976|Bacteroidetes	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
TLS3_k127_2960742_1	869213.JCM21142_41458	6.828e-111	370.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,47XWD@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase III, delta' subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
TLS3_k127_2970810_2	869213.JCM21142_72658	1.045e-90	304.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_2970810_0	869213.JCM21142_72659	5.259e-205	646.0	COG0673@1|root,COG0673@2|Bacteria,4NF9M@976|Bacteroidetes,47JCP@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
TLS3_k127_2970810_1	1168034.FH5T_09240	9.623e-196	622.0	COG1262@1|root,COG3005@1|root,COG1262@2|Bacteria,COG3005@2|Bacteria,4NEUZ@976|Bacteroidetes,2FQ5J@200643|Bacteroidia	976|Bacteroidetes	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,FGE-sulfatase
TLS3_k127_2970810_3	742725.HMPREF9450_01363	1.623e-86	289.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,4NMAJ@976|Bacteroidetes,2FNTE@200643|Bacteroidia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
TLS3_k127_2979657_0	1121912.AUHD01000017_gene3524	5.974e-35	139.0	COG0438@1|root,COG0438@2|Bacteria,4NHPJ@976|Bacteroidetes,1HZFJ@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_2979657_2	1158294.JOMI01000004_gene3459	8.982e-11	75.0	2B0AS@1|root,31SMT@2|Bacteria,4NQFB@976|Bacteroidetes,2FRMQ@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_2979657_1	517418.Ctha_1422	6.282e-17	93.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_5,Big_5,fn3
TLS3_k127_2984702_2	1123008.KB905695_gene2633	3.017e-28	120.0	2DP7Y@1|root,330X4@2|Bacteria,4NUP0@976|Bacteroidetes,2FV9D@200643|Bacteroidia,22YUI@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2984702_1	886379.AEWI01000001_gene1716	2.517e-156	499.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,2FMNF@200643|Bacteroidia,3XJ7Q@558415|Marinilabiliaceae	976|Bacteroidetes	O	Pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_2984702_0	694427.Palpr_1780	7.079e-263	832.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,2FM1K@200643|Bacteroidia,22XI8@171551|Porphyromonadaceae	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
TLS3_k127_3024164_0	857293.CAAU_2006	5.257e-132	444.0	COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,247JV@186801|Clostridia,36E8E@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
TLS3_k127_3024164_2	264732.Moth_1388	8.085e-36	152.0	COG0437@1|root,COG0437@2|Bacteria,1V35R@1239|Firmicutes,24FIZ@186801|Clostridia,42GXV@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S dicluster domain	dmsB	-	-	ko:K00184,ko:K07307	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3,5.A.3.3	-	-	Fer4_11,Fer4_3,Fer4_4
TLS3_k127_3024164_1	555079.Toce_1559	1.835e-55	209.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,25E6I@186801|Clostridia,42FZM@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Cys Met metabolism	megL	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
TLS3_k127_3024164_3	626522.GCWU000325_00948	3.326e-27	111.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,2FM57@200643|Bacteroidia,1WCTE@1283313|Alloprevotella	976|Bacteroidetes	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
TLS3_k127_3053586_12	1380384.JADN01000006_gene2393	1.442e-45	173.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1HY7Q@117743|Flavobacteriia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_3053586_7	1408473.JHXO01000001_gene2432	5.048e-90	309.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,2FQ9F@200643|Bacteroidia	976|Bacteroidetes	S	Ser Thr phosphatase family protein	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
TLS3_k127_3053586_5	694427.Palpr_0609	7.801e-115	380.0	COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,2FN97@200643|Bacteroidia,22WGJ@171551|Porphyromonadaceae	976|Bacteroidetes	S	glycosyl transferase family 2	wbbL_1	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
TLS3_k127_3053586_10	468059.AUHA01000003_gene1803	2.342e-71	251.0	COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,1IRHE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Bacterial lipid A biosynthesis acyltransferase	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
TLS3_k127_3053586_8	1168289.AJKI01000031_gene1004	3.506e-88	298.0	COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,2FNAK@200643|Bacteroidia,3XJ5Z@558415|Marinilabiliaceae	976|Bacteroidetes	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
TLS3_k127_3053586_3	468059.AUHA01000003_gene1561	4.646e-144	469.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,1INWM@117747|Sphingobacteriia	976|Bacteroidetes	J	2-methylthioadenine synthetase	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
TLS3_k127_3053586_11	742766.HMPREF9455_01090	3.516e-50	186.0	2DB9P@1|root,2Z7Y1@2|Bacteria,4NHQN@976|Bacteroidetes,2G10W@200643|Bacteroidia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_3053586_0	1168289.AJKI01000031_gene1002	8.385e-189	598.0	COG1875@1|root,COG1875@2|Bacteria,4NDUI@976|Bacteroidetes,2FP3H@200643|Bacteroidia,3XJ4X@558415|Marinilabiliaceae	976|Bacteroidetes	T	PIN domain	ybeZ_1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
TLS3_k127_3053586_2	927658.AJUM01000034_gene133	1.014e-150	489.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,2FNFB@200643|Bacteroidia,3XIQR@558415|Marinilabiliaceae	976|Bacteroidetes	H	Mur ligase middle domain	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
TLS3_k127_3053586_4	1453503.AU05_25470	1.348e-126	426.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1YIH6@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
TLS3_k127_3053586_9	1168034.FH5T_05815	2.137e-83	297.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,2FQ2M@200643|Bacteroidia	976|Bacteroidetes	S	Peptidase, M28 family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
TLS3_k127_3053586_6	765420.OSCT_2920	1.527e-111	372.0	COG0861@1|root,COG0861@2|Bacteria,2G66P@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
TLS3_k127_3053586_13	1408813.AYMG01000025_gene2644	2.167e-43	164.0	COG4232@1|root,COG4232@2|Bacteria,4PMPN@976|Bacteroidetes,1ISJ4@117747|Sphingobacteriia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
TLS3_k127_3053586_1	1123008.KB905705_gene933	3.426e-166	526.0	COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae	976|Bacteroidetes	G	Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
TLS3_k127_3053586_14	1121396.KB893128_gene4400	1.158e-23	102.0	COG0716@1|root,COG0716@2|Bacteria,1N2QA@1224|Proteobacteria,42NXA@68525|delta/epsilon subdivisions,2WVEA@28221|Deltaproteobacteria,2MNGC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3055310_3	313603.FB2170_16706	2.013e-27	112.0	COG1347@1|root,COG1347@2|Bacteria,4NGD9@976|Bacteroidetes,1HXGP@117743|Flavobacteriia,2PGK4@252356|Maribacter	976|Bacteroidetes	C	Rnf-Nqr subunit, membrane protein	nqrD	-	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
TLS3_k127_3055310_1	1168289.AJKI01000031_gene1045	1.774e-102	336.0	COG2209@1|root,COG2209@2|Bacteria,4NEU0@976|Bacteroidetes,2FMW9@200643|Bacteroidia,3XJC8@558415|Marinilabiliaceae	976|Bacteroidetes	C	Rnf-Nqr subunit, membrane protein	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
TLS3_k127_3055310_0	1211813.CAPH01000004_gene1219	7.295e-191	603.0	COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,2FN44@200643|Bacteroidia,22UP8@171550|Rikenellaceae	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
TLS3_k127_3055310_2	411476.BACOVA_05360	2.376e-91	311.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,2FKZQ@200643|Bacteroidia,4AMF0@815|Bacteroidaceae	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
TLS3_k127_3107732_1	1191523.MROS_0944	3.431e-84	296.0	COG3579@1|root,COG3579@2|Bacteria	2|Bacteria	E	homocysteine catabolic process	-	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1,Peptidase_C1_2
TLS3_k127_3107732_4	1189612.A33Q_1268	7.607e-06	58.0	COG1073@1|root,COG1073@2|Bacteria,4NFRN@976|Bacteroidetes,47KAI@768503|Cytophagia	976|Bacteroidetes	E	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
TLS3_k127_3107732_0	484018.BACPLE_02300	5.555e-154	500.0	COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,2FNT1@200643|Bacteroidia,4AKAI@815|Bacteroidaceae	976|Bacteroidetes	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD2_2	-	3.1.11.5	ko:K01144	-	-	-	-	ko00000,ko01000	-	-	-	AAA_30,UvrD_C_2
TLS3_k127_3107732_3	216432.CA2559_10603	5.302e-13	79.0	29SSC@1|root,30DYA@2|Bacteria,4NM51@976|Bacteroidetes,1I24J@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3822)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3822
TLS3_k127_3107732_2	694427.Palpr_1478	8.59e-58	206.0	COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,2FSR0@200643|Bacteroidia,22XZ4@171551|Porphyromonadaceae	976|Bacteroidetes	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
TLS3_k127_3118028_2	616991.JPOO01000003_gene1247	1.868e-90	305.0	COG2152@1|root,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes,1HYH2@117743|Flavobacteriia,23H2S@178469|Arenibacter	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_3118028_3	234267.Acid_2311	6.966e-19	91.0	COG4704@1|root,COG4704@2|Bacteria,3Y5XJ@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
TLS3_k127_3118028_0	694427.Palpr_0130	1.597e-183	586.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,2FRUW@200643|Bacteroidia,22Y1X@171551|Porphyromonadaceae	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
TLS3_k127_3118028_1	694427.Palpr_0129	3.707e-93	312.0	COG1562@1|root,COG1562@2|Bacteria	2|Bacteria	I	ergosterol biosynthetic process	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
TLS3_k127_3118902_0	1121904.ARBP01000043_gene2123	2.217e-297	928.0	COG3292@1|root,COG3292@2|Bacteria,4NE4U@976|Bacteroidetes,47JHS@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3118902_8	269797.Mbar_A2782	3.295e-08	64.0	COG1520@1|root,COG1572@1|root,COG3291@1|root,arCOG02516@1|root,arCOG02492@2157|Archaea,arCOG02508@2157|Archaea,arCOG02516@2157|Archaea,arCOG02532@2157|Archaea,2Y7Q0@28890|Euryarchaeota	28890|Euryarchaeota	KLT	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PQQ_3
TLS3_k127_3118902_4	1123008.KB905693_gene1177	2.423e-112	370.0	COG3394@1|root,COG3394@2|Bacteria,4NFY5@976|Bacteroidetes	976|Bacteroidetes	G	PFAM YdjC family protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
TLS3_k127_3118902_7	143224.JQMD01000002_gene249	6.438e-64	226.0	COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,1IAHR@117743|Flavobacteriia	976|Bacteroidetes	G	SIS domain	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
TLS3_k127_3118902_2	1434325.AZQN01000006_gene3304	1.851e-171	558.0	COG0546@1|root,COG2870@1|root,COG0546@2|Bacteria,COG2870@2|Bacteria,4NJ8F@976|Bacteroidetes,47MRA@768503|Cytophagia	976|Bacteroidetes	M	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase,PfkB
TLS3_k127_3118902_3	313628.LNTAR_18720	7.654e-135	440.0	COG1915@1|root,COG1915@2|Bacteria	2|Bacteria	E	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3118902_1	471854.Dfer_5652	1.104e-201	638.0	COG2942@1|root,COG2942@2|Bacteria,4NHTQ@976|Bacteroidetes,47KVQ@768503|Cytophagia	976|Bacteroidetes	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
TLS3_k127_3118902_5	700598.Niako_0967	2.998e-90	317.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1IVD1@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
TLS3_k127_3118902_6	1131266.ARWQ01000001_gene1238	2.816e-71	250.0	arCOG08055@1|root,arCOG08055@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_3165502_4	1168034.FH5T_18660	3.092e-33	139.0	2EI0T@1|root,33BSA@2|Bacteria,4NYPN@976|Bacteroidetes,2FPS1@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3165502_1	543632.JOJL01000002_gene8026	1.09e-63	242.0	COG4733@1|root,COG4733@2|Bacteria,2HJAB@201174|Actinobacteria,4DI0K@85008|Micromonosporales	201174|Actinobacteria	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_6
TLS3_k127_3165502_3	1191523.MROS_0085	2.657e-53	212.0	COG2730@1|root,COG3401@1|root,COG2730@2|Bacteria,COG3401@2|Bacteria	2|Bacteria	Q	FG-GAP repeat protein	-	-	3.2.1.4,4.2.2.2	ko:K01179,ko:K01728,ko:K03932	ko00040,ko00500,ko01100,ko02024,map00040,map00500,map01100,map02024	-	R02361,R06200,R06240,R11307,R11308	RC00049,RC00705	ko00000,ko00001,ko01000	-	CE1,GH5,GH9	-	Beta_helix,Cellulase,DUF1565,DUF4990
TLS3_k127_3165502_0	869213.JCM21142_41900	3.142e-149	497.0	COG0823@1|root,COG2885@1|root,COG3291@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,COG3291@2|Bacteria,4NE6G@976|Bacteroidetes,47K1N@768503|Cytophagia	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,PKD
TLS3_k127_3170496_1	742817.HMPREF9449_01830	1.233e-79	271.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,2FPDM@200643|Bacteroidia,22X2U@171551|Porphyromonadaceae	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
TLS3_k127_3170496_2	1408473.JHXO01000004_gene141	2.679e-15	81.0	COG2198@1|root,COG2198@2|Bacteria,4NZRF@976|Bacteroidetes,2FZRE@200643|Bacteroidia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3170496_3	338963.Pcar_1874	5.925e-12	70.0	COG1366@1|root,COG1366@2|Bacteria,1MZE8@1224|Proteobacteria,42V4W@68525|delta/epsilon subdivisions,2WR6H@28221|Deltaproteobacteria,43V3T@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
TLS3_k127_3170496_0	742725.HMPREF9450_00786	1.057e-162	520.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,2FM5N@200643|Bacteroidia,22UVR@171550|Rikenellaceae	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
TLS3_k127_3178794_2	861299.J421_0703	5.811e-12	68.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Sulfatase
TLS3_k127_3178794_0	313603.FB2170_03170	2.026e-258	823.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HWM8@117743|Flavobacteriia,2PGC9@252356|Maribacter	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_3178794_1	1196322.A370_04438	5.49e-35	138.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,36EFE@31979|Clostridiaceae	186801|Clostridia	C	Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
TLS3_k127_3179398_5	1121875.KB907551_gene998	9.802e-20	100.0	COG4938@1|root,COG4938@2|Bacteria,4NMVA@976|Bacteroidetes,1HYGT@117743|Flavobacteriia	976|Bacteroidetes	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,DUF3696
TLS3_k127_3179398_6	1094466.KQS_08890	6.546e-11	70.0	2ABSC@1|root,3118T@2|Bacteria,4PD7Y@976|Bacteroidetes,1IDRN@117743|Flavobacteriia,2NZ1B@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3179398_1	1250278.JQNQ01000001_gene3686	7.653e-156	506.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HXNG@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase	sad	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_3179398_0	234267.Acid_0504	4.266e-180	574.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_3179398_2	1279009.ADICEAN_03090	4.171e-134	442.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,47U45@768503|Cytophagia	976|Bacteroidetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_3179398_3	290317.Cpha266_2350	2.655e-103	360.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
TLS3_k127_3179398_4	472759.Nhal_0728	1.717e-44	164.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,1S4GM@1236|Gammaproteobacteria,1WYNP@135613|Chromatiales	135613|Chromatiales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_3207118_3	1123511.KB905866_gene3793	2.624e-15	82.0	COG1846@1|root,COG1846@2|Bacteria,1VME4@1239|Firmicutes,4H6ZU@909932|Negativicutes	909932|Negativicutes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
TLS3_k127_3207118_1	1121904.ARBP01000010_gene2417	2.747e-83	293.0	COG1538@1|root,COG1538@2|Bacteria,4NE4S@976|Bacteroidetes,47KIE@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_3207118_2	929562.Emtol_1454	1.729e-68	245.0	COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes,47MIB@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS3_k127_3207118_0	1519464.HY22_01480	2.104e-204	652.0	COG0841@1|root,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS3_k127_3209976_3	1121288.AULL01000012_gene384	0.0005102	43.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,1HY4W@117743|Flavobacteriia,3ZP1E@59732|Chryseobacterium	976|Bacteroidetes	K	Crp Fnr family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TLS3_k127_3209976_0	1123008.KB905695_gene2501	6.135e-162	522.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	plyA1	-	-	ko:K12547	-	-	-	-	ko00000	-	-	-	Beta_helix,F5_F8_type_C,FIVAR,fn3
TLS3_k127_3209976_1	1346330.M472_04220	1.311e-81	293.0	COG1435@1|root,COG1435@2|Bacteria,4NE0A@976|Bacteroidetes,1IQAB@117747|Sphingobacteriia	976|Bacteroidetes	F	PFAM RagB SusD	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_3,SusD_RagB
TLS3_k127_3209976_2	742766.HMPREF9455_01585	2.559e-76	268.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,23276@171551|Porphyromonadaceae	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_3225450_0	1408473.JHXO01000005_gene1544	4.769e-261	812.0	COG3507@1|root,COG3507@2|Bacteria,4NEVJ@976|Bacteroidetes,2G2PB@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Glyco_hydro_43
TLS3_k127_3225450_1	760192.Halhy_0549	1.627e-256	798.0	28JP4@1|root,2Z9F6@2|Bacteria,4NDYM@976|Bacteroidetes,1IVSV@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3225450_2	1379698.RBG1_1C00001G0518	5.839e-55	218.0	COG0515@1|root,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
TLS3_k127_3230006_1	1501391.LG35_01590	3.012e-34	132.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,2FMCA@200643|Bacteroidia,22U9E@171550|Rikenellaceae	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
TLS3_k127_3230006_2	1033732.CAHI01000022_gene1511	1.921e-28	123.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
TLS3_k127_3230006_0	880526.KE386488_gene567	8.994e-182	577.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,2FNP7@200643|Bacteroidia,22UPH@171550|Rikenellaceae	976|Bacteroidetes	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
TLS3_k127_3257185_3	1122931.AUAE01000008_gene4059	1.64e-54	194.0	COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,2FSI2@200643|Bacteroidia,22XWH@171551|Porphyromonadaceae	976|Bacteroidetes	T	Molecular chaperone DnaK	yocK	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
TLS3_k127_3257185_4	1408473.JHXO01000001_gene2182	4.272e-45	168.0	COG3787@1|root,COG3787@2|Bacteria,4NSSF@976|Bacteroidetes	976|Bacteroidetes	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
TLS3_k127_3257185_2	1408473.JHXO01000001_gene2186	3.482e-64	225.0	COG0163@1|root,COG0163@2|Bacteria,4NIBD@976|Bacteroidetes	976|Bacteroidetes	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
TLS3_k127_3257185_1	1168034.FH5T_09295	2.496e-85	288.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,2FNXN@200643|Bacteroidia	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
TLS3_k127_3257185_0	927658.AJUM01000047_gene2745	3.092e-164	521.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,2FM5R@200643|Bacteroidia,3XIIJ@558415|Marinilabiliaceae	976|Bacteroidetes	J	Anticodon-binding domain of tRNA	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
TLS3_k127_3271664_0	1047013.AQSP01000092_gene315	0.0	1052.0	COG3250@1|root,COG3250@2|Bacteria,2NQEM@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolases family 2, TIM barrel domain	lacZ	GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0032991,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575,GO:1902494	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
TLS3_k127_3271664_3	1237149.C900_05595	1.31e-44	166.0	COG2852@1|root,COG2852@2|Bacteria,4NVZP@976|Bacteroidetes,47W1D@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
TLS3_k127_3271664_5	2325.TKV_c20000	4.985e-21	101.0	COG0746@1|root,COG0746@2|Bacteria,1VA6T@1239|Firmicutes,24JG6@186801|Clostridia,42GTS@68295|Thermoanaerobacterales	186801|Clostridia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
TLS3_k127_3271664_2	1499967.BAYZ01000076_gene753	1.077e-101	338.0	COG0412@1|root,COG0412@2|Bacteria,2NPZG@2323|unclassified Bacteria	2|Bacteria	Q	Dienelactone hydrolase family	dlhH	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
TLS3_k127_3271664_1	1499967.BAYZ01000076_gene754	7.311e-141	456.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	aslB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
TLS3_k127_3271664_4	693979.Bache_3290	5.866e-23	102.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,4NEV7@976|Bacteroidetes,2FKZX@200643|Bacteroidia,4AMKR@815|Bacteroidaceae	976|Bacteroidetes	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA
TLS3_k127_3273577_1	553177.CAPSP0001_1295	1.898e-60	215.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,1HXKT@117743|Flavobacteriia,1EQCZ@1016|Capnocytophaga	976|Bacteroidetes	H	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
TLS3_k127_3273577_5	1168289.AJKI01000021_gene1797	3.315e-24	109.0	29CCT@1|root,2ZZB9@2|Bacteria,4NM9K@976|Bacteroidetes,2FNRJ@200643|Bacteroidia,3XK4I@558415|Marinilabiliaceae	976|Bacteroidetes	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
TLS3_k127_3273577_0	926551.KB900739_gene59	3.923e-103	347.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,1HWNH@117743|Flavobacteriia,1ERQA@1016|Capnocytophaga	976|Bacteroidetes	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
TLS3_k127_3273577_2	999419.HMPREF1077_01816	1.806e-54	202.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,2FNCU@200643|Bacteroidia,22X60@171551|Porphyromonadaceae	976|Bacteroidetes	KMT	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
TLS3_k127_3273577_4	1121094.KB894657_gene2555	2.252e-31	130.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,2FM72@200643|Bacteroidia,4AKT0@815|Bacteroidaceae	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_3273577_3	667015.Bacsa_3301	3.78e-40	156.0	COG4219@1|root,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,2FNCU@200643|Bacteroidia,4ANSE@815|Bacteroidaceae	976|Bacteroidetes	KT	COG NOG25147 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
TLS3_k127_3277859_1	869213.JCM21142_41953	2.894e-94	317.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia	976|Bacteroidetes	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS3_k127_3277859_4	385682.AFSL01000065_gene1648	3.283e-15	78.0	COG0236@1|root,COG0236@2|Bacteria,4NW2I@976|Bacteroidetes,2G28V@200643|Bacteroidia,3XKDE@558415|Marinilabiliaceae	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
TLS3_k127_3277859_0	1189612.A33Q_2994	3.108e-108	379.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia	976|Bacteroidetes	DM	TIGRFAM capsular exopolysaccharide family	wzc	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
TLS3_k127_3277859_3	869213.JCM21142_52344	5.729e-36	146.0	COG1596@1|root,COG1596@2|Bacteria,4NNJT@976|Bacteroidetes,47PCB@768503|Cytophagia	976|Bacteroidetes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
TLS3_k127_3277859_2	927658.AJUM01000034_gene378	2.974e-48	175.0	COG2148@1|root,COG2148@2|Bacteria,4NER4@976|Bacteroidetes,2FNC2@200643|Bacteroidia,3XIYM@558415|Marinilabiliaceae	976|Bacteroidetes	M	CoA-binding domain	-	-	-	ko:K13012	-	-	-	-	ko00000,ko01005	-	-	-	Bac_transf,CoA_binding_3
TLS3_k127_3282635_1	1168034.FH5T_16285	9.136e-166	530.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,SLH,SprB,VCBS
TLS3_k127_3282635_0	869213.JCM21142_72604	1.657e-237	747.0	COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,47M5S@768503|Cytophagia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
TLS3_k127_3287387_2	927658.AJUM01000042_gene1523	3.291e-33	134.0	COG0511@1|root,COG0511@2|Bacteria,4PNSG@976|Bacteroidetes	976|Bacteroidetes	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
TLS3_k127_3287387_1	869213.JCM21142_58	8.376e-172	552.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,47YHK@768503|Cytophagia	976|Bacteroidetes	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
TLS3_k127_3287387_0	927658.AJUM01000042_gene1521	5.733e-209	657.0	COG4799@1|root,COG4799@2|Bacteria,4NG2H@976|Bacteroidetes,2FQSM@200643|Bacteroidia,3XIS9@558415|Marinilabiliaceae	976|Bacteroidetes	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
TLS3_k127_3316135_1	1168289.AJKI01000053_gene772	3.659e-28	114.0	COG0329@1|root,COG0329@2|Bacteria,4NHBA@976|Bacteroidetes,2FM35@200643|Bacteroidia,3XKR3@558415|Marinilabiliaceae	976|Bacteroidetes	EM	Dihydrodipicolinate synthetase family	-	-	4.1.3.3,4.2.1.41,4.3.3.7	ko:K01639,ko:K01707,ko:K01714	ko00053,ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00053,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R01811,R02279,R10147	RC00159,RC00600,RC00678,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
TLS3_k127_3316135_0	1279009.ADICEAN_02558	1.278e-199	630.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,47KQ9@768503|Cytophagia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
TLS3_k127_3346812_0	234267.Acid_5499	4.076e-219	692.0	28KG3@1|root,2ZA20@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FixG_C,Peptidase_M6
TLS3_k127_3346812_3	886379.AEWI01000012_gene1148	7.174e-42	158.0	COG1238@1|root,COG1238@2|Bacteria,4NQAX@976|Bacteroidetes,2FRY9@200643|Bacteroidia,3XK2Z@558415|Marinilabiliaceae	976|Bacteroidetes	S	SNARE-like domain protein	yqaA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
TLS3_k127_3346812_2	926562.Oweho_1972	7.978e-77	269.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1HX0P@117743|Flavobacteriia,2PAN2@246874|Cryomorphaceae	976|Bacteroidetes	M	NAD(P)H-binding	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
TLS3_k127_3346812_1	1168034.FH5T_09175	5.068e-212	667.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,2FQNW@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_3346812_4	1122947.FR7_2190	7.154e-34	132.0	COG3861@1|root,COG3861@2|Bacteria,1V5R4@1239|Firmicutes	1239|Firmicutes	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	PRC
TLS3_k127_3363579_0	999419.HMPREF1077_01210	8.057e-174	561.0	COG0490@1|root,COG2985@1|root,COG0490@2|Bacteria,COG2985@2|Bacteria,4NEBW@976|Bacteroidetes,2FMDF@200643|Bacteroidia,22W10@171551|Porphyromonadaceae	976|Bacteroidetes	P	TrkA C-terminal domain protein	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
TLS3_k127_3363579_2	1124780.ANNU01000021_gene3028	6.797e-94	324.0	COG0845@1|root,COG0845@2|Bacteria,4NGSC@976|Bacteroidetes,47TMZ@768503|Cytophagia	976|Bacteroidetes	M	HlyD membrane-fusion protein of T1SS	-	-	-	-	-	-	-	-	-	-	-	-	HlyD,HlyD_3,HlyD_D23
TLS3_k127_3363579_5	1111730.ATTM01000004_gene2011	1.502e-37	145.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,1I30U@117743|Flavobacteriia,2NW8W@237|Flavobacterium	976|Bacteroidetes	S	Thiol-disulfide oxidoreductase	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
TLS3_k127_3363579_1	889378.Spiaf_0923	1.008e-122	417.0	COG1331@1|root,COG1331@2|Bacteria	2|Bacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	DsbC,Thioredox_DsbH
TLS3_k127_3363579_3	1123008.KB905699_gene1903	3.41e-77	269.0	COG1082@1|root,COG1082@2|Bacteria,4NFQY@976|Bacteroidetes	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_3363579_4	1122990.BAJH01000007_gene1171	4.482e-46	174.0	COG2942@1|root,COG2942@2|Bacteria,4NEH7@976|Bacteroidetes,2FM9N@200643|Bacteroidia	976|Bacteroidetes	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	bfce	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
TLS3_k127_3382814_2	1150600.ADIARSV_3569	3.889e-19	88.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,1IPQ2@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
TLS3_k127_3382814_3	709991.Odosp_1779	5.271e-16	83.0	COG4770@1|root,COG4770@2|Bacteria,4NWQ0@976|Bacteroidetes,2FUXX@200643|Bacteroidia,22YSD@171551|Porphyromonadaceae	976|Bacteroidetes	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
TLS3_k127_3382814_0	927658.AJUM01000034_gene70	3.769e-273	846.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,2FPY6@200643|Bacteroidia,3XJAQ@558415|Marinilabiliaceae	976|Bacteroidetes	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
TLS3_k127_3382814_1	869213.JCM21142_31180	1.024e-100	337.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,47JHT@768503|Cytophagia	976|Bacteroidetes	S	Permease YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
TLS3_k127_3415870_0	1094980.Mpsy_0312	2.559e-112	373.0	COG0477@1|root,arCOG00143@2157|Archaea,2XUTR@28890|Euryarchaeota,2N94Q@224756|Methanomicrobia	224756|Methanomicrobia	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_3415870_2	1235813.JCM10003_89	5.157e-58	205.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,2FNMW@200643|Bacteroidia,4AP5M@815|Bacteroidaceae	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
TLS3_k127_3415870_3	443143.GM18_1509	5.218e-37	146.0	COG1971@1|root,COG1971@2|Bacteria,1NWBY@1224|Proteobacteria,42RE2@68525|delta/epsilon subdivisions,2WNEN@28221|Deltaproteobacteria,43THX@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
TLS3_k127_3415870_1	1408473.JHXO01000006_gene1027	2.117e-64	228.0	COG0664@1|root,COG0664@2|Bacteria,4P3ES@976|Bacteroidetes	976|Bacteroidetes	T	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
TLS3_k127_3415941_3	694427.Palpr_0839	2.785e-50	197.0	COG2885@1|root,COG2885@2|Bacteria,4PMJV@976|Bacteroidetes,2G0E0@200643|Bacteroidia,2325J@171551|Porphyromonadaceae	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3415941_0	869213.JCM21142_134740	5.977e-110	365.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,47K20@768503|Cytophagia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
TLS3_k127_3415941_1	927658.AJUM01000034_gene419	3.468e-94	314.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,2FNVR@200643|Bacteroidia,3XIZS@558415|Marinilabiliaceae	976|Bacteroidetes	Q	Permease MlaE	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
TLS3_k127_3415941_2	742767.HMPREF9456_00508	1.198e-83	284.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,2FNHF@200643|Bacteroidia,22X4P@171551|Porphyromonadaceae	976|Bacteroidetes	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
TLS3_k127_3421913_3	1408473.JHXO01000004_gene144	5.001e-119	404.0	COG0574@1|root,COG0574@2|Bacteria,4NGSQ@976|Bacteroidetes,2FM60@200643|Bacteroidia	976|Bacteroidetes	GKT	Pyruvate phosphate dikinase, PEP pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
TLS3_k127_3421913_12	304371.MCP_1677	1.593e-21	110.0	COG0642@1|root,COG2202@1|root,arCOG02366@1|root,arCOG02366@2157|Archaea,arCOG06192@2157|Archaea,arCOG06918@2157|Archaea	2157|Archaea	T	Pas domain	ark3	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_2,MCPsignal,PAS,PAS_4,PAS_8,PAS_9,Response_reg
TLS3_k127_3421913_2	1211813.CAPH01000012_gene318	3.857e-154	493.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,2FME7@200643|Bacteroidia,22URR@171550|Rikenellaceae	976|Bacteroidetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
TLS3_k127_3421913_0	742817.HMPREF9449_02657	3.018e-274	855.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,2FN08@200643|Bacteroidia,22WBU@171551|Porphyromonadaceae	976|Bacteroidetes	C	2-oxoacid acceptor oxidoreductase, alpha subunit	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
TLS3_k127_3421913_5	643867.Ftrac_1571	9.276e-91	305.0	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,47MMI@768503|Cytophagia	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
TLS3_k127_3421913_10	1408473.JHXO01000004_gene152	5.485e-28	119.0	COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,2FU10@200643|Bacteroidia	976|Bacteroidetes	M	Outer membrane protein (OmpH-like)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TLS3_k127_3421913_8	1408473.JHXO01000004_gene153	4.3e-58	206.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,2FQDW@200643|Bacteroidia	976|Bacteroidetes	M	membrane	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TLS3_k127_3421913_1	1408473.JHXO01000004_gene154	8.029e-274	865.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,2FM76@200643|Bacteroidia	976|Bacteroidetes	M	Outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
TLS3_k127_3421913_4	742767.HMPREF9456_02482	4.576e-96	320.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,2FMM4@200643|Bacteroidia,22WWT@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
TLS3_k127_3421913_11	1380384.JADN01000008_gene1263	2.988e-27	121.0	COG3637@1|root,COG3637@2|Bacteria,4NF6B@976|Bacteroidetes,1I060@117743|Flavobacteriia	976|Bacteroidetes	M	Inorganic polyphosphate kinase	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_3421913_13	694427.Palpr_2178	2.203e-07	61.0	COG3637@1|root,COG3637@2|Bacteria,4NXWF@976|Bacteroidetes	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3421913_6	886379.AEWI01000078_gene1984	8.189e-71	249.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,2FMTM@200643|Bacteroidia,3XJ1Y@558415|Marinilabiliaceae	976|Bacteroidetes	G	ATP-NAD kinase	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
TLS3_k127_3421913_7	385682.AFSL01000041_gene275	7.116e-69	240.0	COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,2FT2B@200643|Bacteroidia,3XIWD@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
TLS3_k127_3421913_9	1408473.JHXO01000004_gene159	1.089e-54	193.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,2FM21@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
TLS3_k127_3423760_2	1168034.FH5T_00685	6.123e-60	219.0	COG2972@1|root,COG2972@2|Bacteria,4NGQZ@976|Bacteroidetes,2FMGN@200643|Bacteroidia	976|Bacteroidetes	T	Histidine kinase	cheA	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
TLS3_k127_3423760_1	869213.JCM21142_223	8.623e-82	279.0	COG3279@1|root,COG3279@2|Bacteria,4NIXU@976|Bacteroidetes,47M0C@768503|Cytophagia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_3423760_0	1121011.AUCB01000005_gene2382	1.198e-179	568.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,1HZS8@117743|Flavobacteriia,23GI6@178469|Arenibacter	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_3433947_1	1121097.JCM15093_1960	6.002e-108	352.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,2FM57@200643|Bacteroidia,4AMXR@815|Bacteroidaceae	976|Bacteroidetes	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
TLS3_k127_3433947_6	435591.BDI_3761	3.789e-48	176.0	COG2954@1|root,COG2954@2|Bacteria,4NNGE@976|Bacteroidetes,2FNH1@200643|Bacteroidia,22XW0@171551|Porphyromonadaceae	976|Bacteroidetes	S	Adenylate cyclase	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
TLS3_k127_3433947_5	1124780.ANNU01000061_gene923	4.131e-52	186.0	COG3169@1|root,COG3169@2|Bacteria,4NQH4@976|Bacteroidetes,47QJ9@768503|Cytophagia	976|Bacteroidetes	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
TLS3_k127_3433947_4	1499967.BAYZ01000095_gene4057	8.412e-64	230.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlA	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
TLS3_k127_3433947_3	158190.SpiGrapes_0922	1.89e-92	313.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlA	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
TLS3_k127_3433947_0	1499967.BAYZ01000028_gene1265	3.978e-143	465.0	COG1509@1|root,COG1509@2|Bacteria,2NNY6@2323|unclassified Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	kamA	-	5.4.3.2	ko:K01843,ko:K19810	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000,ko03012	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
TLS3_k127_3433947_8	1408473.JHXO01000008_gene2691	2.111e-32	130.0	COG1186@1|root,COG1186@2|Bacteria,4NQ41@976|Bacteroidetes,2FY9G@200643|Bacteroidia	976|Bacteroidetes	J	RF-1 domain	arfB	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
TLS3_k127_3433947_2	886379.AEWI01000094_gene1541	7.543e-104	345.0	COG0697@1|root,COG0697@2|Bacteria,4NIBF@976|Bacteroidetes,2FR06@200643|Bacteroidia,3XJ36@558415|Marinilabiliaceae	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_3433947_7	760192.Halhy_4949	4.537e-47	173.0	COG3408@1|root,COG3408@2|Bacteria,4NESP@976|Bacteroidetes,1INWR@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Bacterial alpha-L-rhamnosidase	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
TLS3_k127_3435536_2	1396141.BATP01000004_gene5818	0.0003638	46.0	COG0657@1|root,COG0657@2|Bacteria,46U2T@74201|Verrucomicrobia,2IV28@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
TLS3_k127_3435536_0	1168034.FH5T_12255	1.877e-246	771.0	COG0665@1|root,COG0665@2|Bacteria,4NFTJ@976|Bacteroidetes,2G18H@200643|Bacteroidia	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
TLS3_k127_3435536_1	1127673.GLIP_1171	7.12e-237	754.0	COG3119@1|root,COG3408@1|root,COG3119@2|Bacteria,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF4976,Sulfatase
TLS3_k127_3442122_3	760192.Halhy_2966	8.247e-56	200.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,1IQ1H@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
TLS3_k127_3442122_2	521097.Coch_1821	2.173e-74	258.0	COG1045@1|root,COG1045@2|Bacteria,4NGZ7@976|Bacteroidetes,1HWYR@117743|Flavobacteriia,1ERGR@1016|Capnocytophaga	976|Bacteroidetes	E	Psort location Cytoplasmic, score 9.97	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
TLS3_k127_3442122_0	1123248.KB893385_gene4793	7.008e-149	476.0	COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,1IVMI@117747|Sphingobacteriia	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47	ko:K01738,ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_3442122_1	1237149.C900_01430	5.504e-109	361.0	COG0389@1|root,COG0389@2|Bacteria,4NF1Y@976|Bacteroidetes,47JB9@768503|Cytophagia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
TLS3_k127_3443290_3	1144313.PMI10_03404	3.137e-31	130.0	COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,1HYKJ@117743|Flavobacteriia,2NSU6@237|Flavobacterium	976|Bacteroidetes	O	Belongs to the peptidase S8 family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_3443290_0	1168034.FH5T_03215	8.266e-109	366.0	COG1570@1|root,COG1570@2|Bacteria,4NE64@976|Bacteroidetes,2FMMA@200643|Bacteroidia	976|Bacteroidetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
TLS3_k127_3443290_4	886379.AEWI01000034_gene3011	1.598e-12	69.0	COG1722@1|root,COG1722@2|Bacteria,4NXJV@976|Bacteroidetes,2FVH6@200643|Bacteroidia,3XKF5@558415|Marinilabiliaceae	976|Bacteroidetes	L	Exonuclease VII small subunit	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
TLS3_k127_3443290_2	385682.AFSL01000095_gene831	1.244e-53	191.0	COG3118@1|root,COG3118@2|Bacteria,4NQNX@976|Bacteroidetes,2FSPP@200643|Bacteroidia,3XK5P@558415|Marinilabiliaceae	976|Bacteroidetes	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
TLS3_k127_3443290_1	1341181.FLJC2902T_27320	2.487e-66	229.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,1HX65@117743|Flavobacteriia,2NS73@237|Flavobacterium	976|Bacteroidetes	J	tRNA nucleotidyltransferase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
TLS3_k127_3466245_0	1304885.AUEY01000101_gene2140	0.0	1230.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2MIZ3@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
TLS3_k127_3466245_3	1168034.FH5T_21275	1.286e-110	364.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,2FP3B@200643|Bacteroidia	976|Bacteroidetes	D	tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
TLS3_k127_3466245_1	1286632.P278_07200	4.212e-286	911.0	COG0841@1|root,COG0841@2|Bacteria,4NE3H@976|Bacteroidetes,1HZ8H@117743|Flavobacteriia	976|Bacteroidetes	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS3_k127_3466245_2	1408473.JHXO01000012_gene405	5.143e-241	782.0	COG0841@1|root,COG0841@2|Bacteria,4NH0G@976|Bacteroidetes,2FM3G@200643|Bacteroidia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS3_k127_3466245_4	1286632.P278_07180	1.877e-69	248.0	COG0845@1|root,COG0845@2|Bacteria,4NHJH@976|Bacteroidetes,1I04R@117743|Flavobacteriia	976|Bacteroidetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS3_k127_3466245_5	1235803.C825_01555	6.28e-10	66.0	2DR25@1|root,339UM@2|Bacteria,4NY6Z@976|Bacteroidetes,2FVQE@200643|Bacteroidia,2311T@171551|Porphyromonadaceae	976|Bacteroidetes	S	6-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128
TLS3_k127_3470150_3	1449063.JMLS01000011_gene285	1.136e-37	160.0	COG1404@1|root,COG5492@1|root,COG1404@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3470150_4	985255.APHJ01000054_gene2032	8.256e-29	135.0	COG2911@1|root,COG3209@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,4NKIP@976|Bacteroidetes,1I0IX@117743|Flavobacteriia,2P6AJ@244698|Gillisia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,Gal_Lectin
TLS3_k127_3470150_6	1121101.HMPREF1532_02084	3.012e-06	61.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,2FP6T@200643|Bacteroidia,4AKST@815|Bacteroidaceae	976|Bacteroidetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TLS3_k127_3470150_1	760192.Halhy_3411	2.259e-57	204.0	COG0640@1|root,COG0640@2|Bacteria,4NS23@976|Bacteroidetes,1IT8B@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_DeoR
TLS3_k127_3470150_5	1392493.JIAB01000001_gene525	1.307e-20	101.0	COG0454@1|root,COG0456@2|Bacteria,1VHXZ@1239|Firmicutes,24VJQ@186801|Clostridia	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3470150_2	1121957.ATVL01000008_gene4268	4.592e-40	159.0	COG0463@1|root,COG0463@2|Bacteria,4NKQ4@976|Bacteroidetes,47KJW@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
TLS3_k127_3470150_0	382464.ABSI01000002_gene4296	2.721e-104	350.0	COG0399@1|root,COG0399@2|Bacteria,46SEI@74201|Verrucomicrobia,2ITTP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_3476892_6	999419.HMPREF1077_03219	5.499e-13	76.0	COG1629@1|root,COG4219@1|root,COG1629@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,2FNCU@200643|Bacteroidia,22W9Z@171551|Porphyromonadaceae	976|Bacteroidetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
TLS3_k127_3476892_3	1124780.ANNU01000059_gene859	3.152e-46	170.0	COG3682@1|root,COG3682@2|Bacteria,4NNVM@976|Bacteroidetes,47Q5Z@768503|Cytophagia	976|Bacteroidetes	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
TLS3_k127_3476892_1	1168034.FH5T_04310	2.502e-144	468.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,2FWBI@200643|Bacteroidia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_3476892_5	385682.AFSL01000008_gene2588	1.445e-15	81.0	2CEYK@1|root,31W5M@2|Bacteria,4NQEQ@976|Bacteroidetes,2G265@200643|Bacteroidia,3XK2K@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
TLS3_k127_3476892_0	1408473.JHXO01000006_gene1390	5.376e-171	541.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
TLS3_k127_3476892_4	926562.Oweho_1024	1.862e-25	116.0	28MPU@1|root,2ZAYW@2|Bacteria,4PJIE@976|Bacteroidetes,1I9N3@117743|Flavobacteriia,2PC5G@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3476892_2	1121129.KB903359_gene1199	3.307e-72	249.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,4NMAJ@976|Bacteroidetes,2FNTE@200643|Bacteroidia,22WQ9@171551|Porphyromonadaceae	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
TLS3_k127_3485896_4	385682.AFSL01000043_gene328	2.768e-105	346.0	COG0280@1|root,COG0280@2|Bacteria,4NGX5@976|Bacteroidetes,2FMKY@200643|Bacteroidia,3XJQS@558415|Marinilabiliaceae	976|Bacteroidetes	C	Phosphate acetyl/butaryl transferase	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
TLS3_k127_3485896_0	926549.KI421517_gene3604	0.0	1127.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,47JNC@768503|Cytophagia	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
TLS3_k127_3485896_6	207954.MED92_06866	5.055e-72	251.0	COG0388@1|root,COG0388@2|Bacteria,1MXBR@1224|Proteobacteria,1RQ4Z@1236|Gammaproteobacteria,1XHKT@135619|Oceanospirillales	135619|Oceanospirillales	S	Carbon-nitrogen hydrolase	-	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
TLS3_k127_3485896_5	1121011.AUCB01000002_gene492	6.26e-73	259.0	28I02@1|root,2Z84Y@2|Bacteria,4NE8I@976|Bacteroidetes,1HZJ1@117743|Flavobacteriia,23HRY@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3485896_1	468059.AUHA01000002_gene1235	2.273e-193	619.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1IP46@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
TLS3_k127_3485896_2	1150600.ADIARSV_3095	3.722e-189	599.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1IPEJ@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
TLS3_k127_3485896_3	391596.PBAL39_01677	1.052e-112	370.0	COG2877@1|root,COG2877@2|Bacteria,4NENN@976|Bacteroidetes,1IVW9@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
TLS3_k127_3485896_8	1168034.FH5T_07155	2.513e-30	129.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4367,LolA,LolA_like
TLS3_k127_3485896_10	435591.BDI_0358	2.792e-05	49.0	2C5FT@1|root,33K3C@2|Bacteria,4NZJR@976|Bacteroidetes,2FVX2@200643|Bacteroidia,23169@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3485896_9	435591.BDI_0358	1.454e-07	56.0	2C5FT@1|root,33K3C@2|Bacteria,4NZJR@976|Bacteroidetes,2FVX2@200643|Bacteroidia,23169@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3485896_7	411477.PARMER_02951	5.338e-48	177.0	COG0809@1|root,COG0809@2|Bacteria,4NDZ5@976|Bacteroidetes,2FNJD@200643|Bacteroidia,22X1R@171551|Porphyromonadaceae	976|Bacteroidetes	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
TLS3_k127_3516555_3	1408473.JHXO01000004_gene230	3.456e-115	384.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,2FKYG@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K02484,ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_3516555_5	1408473.JHXO01000004_gene231	6.324e-88	295.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,2FMJH@200643|Bacteroidia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_3516555_6	1408473.JHXO01000004_gene232	3.488e-65	230.0	COG0704@1|root,COG0704@2|Bacteria,4NQ6U@976|Bacteroidetes,2G3C4@200643|Bacteroidia	976|Bacteroidetes	P	PhoU domain	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
TLS3_k127_3516555_0	1408473.JHXO01000004_gene233	1.442e-126	409.0	COG1117@1|root,COG1117@2|Bacteria,4NFAB@976|Bacteroidetes,2FMN7@200643|Bacteroidia	976|Bacteroidetes	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
TLS3_k127_3516555_4	1408473.JHXO01000004_gene234	8.2e-109	362.0	COG0581@1|root,COG0581@2|Bacteria,4NGU9@976|Bacteroidetes,2G353@200643|Bacteroidia	976|Bacteroidetes	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
TLS3_k127_3516555_1	1408473.JHXO01000004_gene235	2.829e-126	409.0	COG0573@1|root,COG0573@2|Bacteria,4NEGX@976|Bacteroidetes,2G32P@200643|Bacteroidia	976|Bacteroidetes	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
TLS3_k127_3516555_2	1168034.FH5T_10220	4.604e-125	406.0	COG0226@1|root,COG0226@2|Bacteria,4NHAS@976|Bacteroidetes,2FQFA@200643|Bacteroidia	976|Bacteroidetes	P	Belongs to the PstS family	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
TLS3_k127_3554866_7	616991.JPOO01000001_gene4555	1.593e-44	162.0	COG0673@1|root,COG0673@2|Bacteria,4NIH0@976|Bacteroidetes	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_3554866_1	1392498.JQLH01000001_gene2493	1.897e-202	642.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,1IGCV@117743|Flavobacteriia,2PI59@252356|Maribacter	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
TLS3_k127_3554866_2	1408473.JHXO01000008_gene2845	1.145e-189	619.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,2FM1K@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
TLS3_k127_3554866_6	694427.Palpr_1541	2.283e-86	294.0	COG3279@1|root,COG3279@2|Bacteria,4NU8X@976|Bacteroidetes,2FR3K@200643|Bacteroidia	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
TLS3_k127_3554866_3	1121930.AQXG01000001_gene1102	3.196e-164	542.0	COG2091@1|root,COG2091@2|Bacteria,4NGXG@976|Bacteroidetes	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_3554866_0	388413.ALPR1_04268	1.272e-298	932.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
TLS3_k127_3554866_5	1279009.ADICEAN_03711	1.761e-91	309.0	2DMY6@1|root,32UCD@2|Bacteria,4NVHX@976|Bacteroidetes,47SQF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3554866_4	471854.Dfer_1270	2.559e-157	511.0	COG4948@1|root,COG4948@2|Bacteria,4NFH1@976|Bacteroidetes,47MTW@768503|Cytophagia	976|Bacteroidetes	M	Enolase C-terminal domain-like	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
TLS3_k127_3596107_18	598659.NAMH_0095	2.28e-42	158.0	COG2033@1|root,COG2033@2|Bacteria,1NDWH@1224|Proteobacteria,42RSM@68525|delta/epsilon subdivisions,2YP5S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Desulfoferrodoxin ferrous iron-binding	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrodox
TLS3_k127_3596107_13	1168289.AJKI01000063_gene3488	8.378e-73	255.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,2FMIQ@200643|Bacteroidia,3XJWX@558415|Marinilabiliaceae	976|Bacteroidetes	M	Peptidase family M23	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_3596107_8	1347393.HG726023_gene3510	2.274e-143	464.0	COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,2FN5M@200643|Bacteroidia,4APAZ@815|Bacteroidaceae	976|Bacteroidetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
TLS3_k127_3596107_5	1408473.JHXO01000001_gene2288	6.506e-179	570.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,2FM5E@200643|Bacteroidia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
TLS3_k127_3596107_20	402612.FP2484	2.877e-12	68.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1I54R@117743|Flavobacteriia,2NXH2@237|Flavobacterium	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
TLS3_k127_3596107_10	742725.HMPREF9450_01628	2.581e-132	432.0	COG1060@1|root,COG1060@2|Bacteria,4NGTU@976|Bacteroidetes,2FX5S@200643|Bacteroidia,22U5C@171550|Rikenellaceae	976|Bacteroidetes	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
TLS3_k127_3596107_9	1408473.JHXO01000001_gene2292	3.866e-134	442.0	COG0260@1|root,COG0260@2|Bacteria,4NDWT@976|Bacteroidetes,2FMS1@200643|Bacteroidia	976|Bacteroidetes	E	Cytosol aminopeptidase family, catalytic domain	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
TLS3_k127_3596107_7	1168034.FH5T_04005	1.653e-143	463.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,2FN0X@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
TLS3_k127_3596107_15	869213.JCM21142_93719	1.682e-63	223.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,47N8D@768503|Cytophagia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
TLS3_k127_3596107_0	886379.AEWI01000037_gene2942	0.0	2466.0	COG4797@1|root,COG4797@2|Bacteria,4PKQS@976|Bacteroidetes,2FP69@200643|Bacteroidia,3XIJ5@558415|Marinilabiliaceae	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
TLS3_k127_3596107_17	575590.HMPREF0156_01037	1.994e-53	190.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
TLS3_k127_3596107_2	1168289.AJKI01000063_gene3474	0.0	1127.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia,3XJQZ@558415|Marinilabiliaceae	976|Bacteroidetes	J	Translation-initiation factor 2	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
TLS3_k127_3596107_4	1408473.JHXO01000001_gene2366	4.421e-214	670.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,2FNJF@200643|Bacteroidia	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
TLS3_k127_3596107_19	694427.Palpr_2899	6.243e-31	126.0	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,2FSM9@200643|Bacteroidia,22Y41@171551|Porphyromonadaceae	976|Bacteroidetes	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
TLS3_k127_3596107_12	880073.Calab_3430	9.18e-76	265.0	COG1313@1|root,COG1313@2|Bacteria,2NP6I@2323|unclassified Bacteria	2|Bacteria	C	Radical SAM superfamily	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
TLS3_k127_3596107_14	1408473.JHXO01000009_gene3332	4.795e-70	244.0	28MFD@1|root,2ZASV@2|Bacteria,4NH4N@976|Bacteroidetes,2FQXU@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3596107_1	1408473.JHXO01000009_gene3333	0.0	1674.0	COG0841@1|root,COG1131@1|root,COG0841@2|Bacteria,COG1131@2|Bacteria,4NF8M@976|Bacteroidetes,2FQY7@200643|Bacteroidia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ACR_tran
TLS3_k127_3596107_3	1168034.FH5T_10400	0.0	1103.0	COG0841@1|root,COG0841@2|Bacteria,4NGCI@976|Bacteroidetes,2FM1V@200643|Bacteroidia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
TLS3_k127_3596107_11	1408473.JHXO01000009_gene3335	2.225e-109	364.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,2FQSG@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23,OEP
TLS3_k127_3596107_6	643867.Ftrac_1071	3.815e-157	509.0	COG1538@1|root,COG1538@2|Bacteria,4NGIX@976|Bacteroidetes,47U8N@768503|Cytophagia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_3596107_16	1408473.JHXO01000009_gene3337	5.148e-58	216.0	COG1277@1|root,COG1277@2|Bacteria,4NI5T@976|Bacteroidetes,2FNVZ@200643|Bacteroidia	976|Bacteroidetes	E	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
TLS3_k127_3619963_2	886379.AEWI01000040_gene2781	4.447e-28	114.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,2FQX0@200643|Bacteroidia,3XJZQ@558415|Marinilabiliaceae	976|Bacteroidetes	O	SmpB protein	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
TLS3_k127_3619963_3	470145.BACCOP_01011	6.919e-06	55.0	2DNHM@1|root,32UIZ@2|Bacteria,4NT16@976|Bacteroidetes,2FN7P@200643|Bacteroidia,4AKSJ@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1282
TLS3_k127_3619963_1	484018.BACPLE_02797	4.159e-120	392.0	COG0324@1|root,COG0324@2|Bacteria,4NFJY@976|Bacteroidetes,2FM0H@200643|Bacteroidia,4AKBM@815|Bacteroidaceae	976|Bacteroidetes	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA2	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
TLS3_k127_3619963_0	1211813.CAPH01000018_gene1099	5.774e-197	631.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,2FN1K@200643|Bacteroidia,22U1Q@171550|Rikenellaceae	976|Bacteroidetes	EU	X-Pro dipeptidyl-peptidase (S15 family)	pop	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
TLS3_k127_3628252_0	1124780.ANNU01000006_gene2920	3.368e-104	358.0	COG2989@1|root,COG2989@2|Bacteria,4NH3J@976|Bacteroidetes,47MU1@768503|Cytophagia	976|Bacteroidetes	T	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
TLS3_k127_3628252_1	1237149.C900_04894	1.809e-61	219.0	COG1376@1|root,COG1376@2|Bacteria,4NNX7@976|Bacteroidetes,47NYB@768503|Cytophagia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
TLS3_k127_366489_1	1121930.AQXG01000001_gene1481	6.308e-27	119.0	COG0457@1|root,COG0457@2|Bacteria	1121930.AQXG01000001_gene1481|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_366489_0	1168034.FH5T_04815	2.29e-177	568.0	COG0667@1|root,COG0667@2|Bacteria,4P42C@976|Bacteroidetes	976|Bacteroidetes	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_366489_2	1121904.ARBP01000055_gene494	3.925e-15	78.0	COG5520@1|root,COG5520@2|Bacteria	2|Bacteria	M	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.136,3.2.1.55,3.2.1.8	ko:K01181,ko:K15921,ko:K15924	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM6,GH43,GH5	-	Beta_helix,Binary_toxB_2,Binary_toxB_3,CBM_6,CW_binding_1,Dockerin_1,Glyco_hydro_10,Glyco_hydro_30,Glyco_hydro_30C,Glyco_hydro_43,Lipase_GDSL_2,RicinB_lectin_2,Ricin_B_lectin
TLS3_k127_3712343_1	1121011.AUCB01000063_gene3241	6.67e-169	539.0	COG3669@1|root,COG3669@2|Bacteria,4NEDX@976|Bacteroidetes,1HZYU@117743|Flavobacteriia,23G1S@178469|Arenibacter	976|Bacteroidetes	G	Alpha-L-fucosidase	fucA	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc
TLS3_k127_3712343_0	1168034.FH5T_10310	3.9e-302	962.0	COG1413@1|root,COG1413@2|Bacteria,4NEZ7@976|Bacteroidetes,2FPRF@200643|Bacteroidia	976|Bacteroidetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,HEAT_2
TLS3_k127_3712343_2	1168034.FH5T_10315	1.169e-91	302.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,2FPMK@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_3725226_1	1137281.D778_02774	1.277e-123	406.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia	976|Bacteroidetes	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS3_k127_3725226_2	385682.AFSL01000065_gene1650	9.405e-121	396.0	COG0171@1|root,COG0171@2|Bacteria,4NEXG@976|Bacteroidetes,2FZBU@200643|Bacteroidia,3XIV0@558415|Marinilabiliaceae	976|Bacteroidetes	H	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_synthase
TLS3_k127_3725226_0	616991.JPOO01000001_gene4212	5.401e-172	553.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,1HZVU@117743|Flavobacteriia	976|Bacteroidetes	IQ	amp-binding	-	-	6.2.1.3	ko:K01897,ko:K18660	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
TLS3_k127_3725226_3	1168289.AJKI01000021_gene1805	1.737e-80	274.0	2E79I@1|root,331T3@2|Bacteria,4P2DF@976|Bacteroidetes,2G216@200643|Bacteroidia,3XIVF@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3725226_5	385682.AFSL01000065_gene1647	1.727e-40	156.0	COG0110@1|root,COG3866@1|root,COG0110@2|Bacteria,COG3866@2|Bacteria,4PISI@976|Bacteroidetes,2G2AM@200643|Bacteroidia,3XKN0@558415|Marinilabiliaceae	976|Bacteroidetes	G	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3725226_4	938709.AUSH02000020_gene1986	1.234e-73	263.0	COG3656@1|root,COG5295@1|root,COG3656@2|Bacteria,COG5295@2|Bacteria,4NHDQ@976|Bacteroidetes	976|Bacteroidetes	UW	fibronectin type III domain protein	-	-	-	ko:K21571	-	-	-	-	ko00000	-	-	-	-
TLS3_k127_3760523_0	1121904.ARBP01000025_gene6070	5.124e-162	520.0	COG2327@1|root,COG2327@2|Bacteria,4NH8A@976|Bacteroidetes,47MJD@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
TLS3_k127_3760523_2	869213.JCM21142_104361	1.202e-121	396.0	COG1145@1|root,COG1145@2|Bacteria,4NI4X@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
TLS3_k127_3760523_1	1047013.AQSP01000140_gene2494	1.135e-124	417.0	COG2234@1|root,COG2234@2|Bacteria,2NRCG@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
TLS3_k127_3760523_4	1168289.AJKI01000015_gene2175	7.048e-56	202.0	COG0664@1|root,COG0664@2|Bacteria,4NRFI@976|Bacteroidetes,2G2ZU@200643|Bacteroidia,3XK1T@558415|Marinilabiliaceae	976|Bacteroidetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
TLS3_k127_3760523_3	1235803.C825_05050	6.707e-75	255.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,2FNQV@200643|Bacteroidia,22WQA@171551|Porphyromonadaceae	976|Bacteroidetes	E	Peptidase family M3	-	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
TLS3_k127_3763731_0	344747.PM8797T_28904	1.873e-193	629.0	COG1520@1|root,COG1957@1|root,COG1520@2|Bacteria,COG1957@2|Bacteria	2|Bacteria	F	ribosylpyrimidine nucleosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,DUF547,PQQ_2,PQQ_3
TLS3_k127_383047_0	509191.AEDB02000094_gene4239	6.249e-169	544.0	COG0507@1|root,COG0507@2|Bacteria,1V4EE@1239|Firmicutes,24PY9@186801|Clostridia,3WN79@541000|Ruminococcaceae	186801|Clostridia	L	HRDC domain	-	-	-	-	-	-	-	-	-	-	-	-	HRDC,PIF1
TLS3_k127_3844761_1	382464.ABSI01000010_gene3488	1.466e-78	284.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
TLS3_k127_3844761_0	1380600.AUYN01000009_gene1094	5.607e-108	362.0	COG1820@1|root,COG1820@2|Bacteria,4NJ35@976|Bacteroidetes,1I1UK@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
TLS3_k127_3844761_2	1209989.TepiRe1_1812	2.924e-52	187.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,42FBV@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
TLS3_k127_3847891_4	177439.DP1784	2.438e-96	321.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42PYJ@68525|delta/epsilon subdivisions,2WKHY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_3847891_2	1121904.ARBP01000013_gene398	5.727e-114	379.0	COG4591@1|root,COG4591@2|Bacteria,4NKUN@976|Bacteroidetes,47TP5@768503|Cytophagia	976|Bacteroidetes	M	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
TLS3_k127_3847891_0	1122176.KB903587_gene4540	2.167e-141	460.0	COG4591@1|root,COG4591@2|Bacteria,4NJRI@976|Bacteroidetes	976|Bacteroidetes	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_3847891_3	880070.Cycma_4195	7.554e-97	323.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,47SW9@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
TLS3_k127_3847891_1	927658.AJUM01000037_gene2070	3.208e-126	420.0	COG0168@1|root,COG0168@2|Bacteria,4NGMF@976|Bacteroidetes,2FNQZ@200643|Bacteroidia,3XIYR@558415|Marinilabiliaceae	976|Bacteroidetes	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
TLS3_k127_3847891_8	1123008.KB905697_gene3255	3.95e-65	230.0	COG1183@1|root,COG1183@2|Bacteria,4PKEX@976|Bacteroidetes,2G3ET@200643|Bacteroidia,22YTS@171551|Porphyromonadaceae	976|Bacteroidetes	I	phosphatidylcholine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
TLS3_k127_3847891_7	1122931.AUAE01000022_gene1484	6.479e-70	248.0	COG0204@1|root,COG0204@2|Bacteria,4NF25@976|Bacteroidetes,2FSAD@200643|Bacteroidia,22XTQ@171551|Porphyromonadaceae	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
TLS3_k127_3847891_5	1287476.HMPREF1651_06725	1.025e-93	313.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,2FKZC@200643|Bacteroidia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
TLS3_k127_3847891_9	1408473.JHXO01000010_gene3506	4.028e-16	84.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
TLS3_k127_3847891_6	385682.AFSL01000009_gene2433	1.499e-75	259.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,3XJC9@558415|Marinilabiliaceae	976|Bacteroidetes	U	SecD/SecF GG Motif	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
TLS3_k127_3847899_6	385682.AFSL01000008_gene2601	1.14e-31	128.0	COG0589@1|root,COG0589@2|Bacteria,4NWVX@976|Bacteroidetes,2FW3E@200643|Bacteroidia,3XIUB@558415|Marinilabiliaceae	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_3847899_4	234267.Acid_0388	5.205e-57	212.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
TLS3_k127_3847899_3	385682.AFSL01000008_gene2549	8.583e-107	355.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,2G2SB@200643|Bacteroidia,3XIJB@558415|Marinilabiliaceae	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_3847899_1	709991.Odosp_2207	5.455e-176	561.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,2FNW8@200643|Bacteroidia,22WZI@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
TLS3_k127_3847899_2	1453500.AT05_07370	1.832e-125	408.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,1HX0S@117743|Flavobacteriia	976|Bacteroidetes	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
TLS3_k127_3847899_0	1124780.ANNU01000032_gene1259	0.0	1494.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,4NFRF@976|Bacteroidetes,47K8Q@768503|Cytophagia	976|Bacteroidetes	E	Vitamin B12 dependent methionine synthase activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
TLS3_k127_3847899_5	56780.SYN_00730	3.368e-42	156.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,2MQGD@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS3_k127_3893847_5	1121896.JMLU01000002_gene360	2.353e-05	55.0	COG3595@1|root,COG3595@2|Bacteria,4NIA2@976|Bacteroidetes,1I0CY@117743|Flavobacteriia,2NUJ6@237|Flavobacterium	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
TLS3_k127_3893847_3	1406840.Q763_16875	9.636e-46	169.0	COG2350@1|root,COG2350@2|Bacteria,4NRC1@976|Bacteroidetes,1I447@117743|Flavobacteriia,2P0AS@237|Flavobacterium	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
TLS3_k127_3893847_0	485918.Cpin_1810	9.708e-303	947.0	COG3250@1|root,COG3250@2|Bacteria,4PHX1@976|Bacteroidetes,1IRK0@117747|Sphingobacteriia	976|Bacteroidetes	G	glycoside hydrolase family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
TLS3_k127_3893847_1	1122176.KB903548_gene1207	6.072e-115	380.0	COG1162@1|root,COG1162@2|Bacteria,4NE24@976|Bacteroidetes,1IP1W@117747|Sphingobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	-	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
TLS3_k127_3893847_4	335541.Swol_1692	2.718e-25	116.0	COG2014@1|root,COG2014@2|Bacteria,1U8UX@1239|Firmicutes,24DPF@186801|Clostridia	186801|Clostridia	S	Putative heavy-metal chelation	-	-	-	-	-	-	-	-	-	-	-	-	DUF364,DUF4213
TLS3_k127_3893847_2	522772.Dacet_1597	2.621e-55	213.0	COG1618@1|root,COG1618@2|Bacteria	2|Bacteria	F	nucleotide phosphatase activity, acting on free nucleotides	mobA	-	2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34	ko:K00943,ko:K02013,ko:K02017,ko:K03574,ko:K03752,ko:K06928	ko00230,ko00240,ko00730,ko00790,ko01100,ko02010,map00230,map00240,map00730,map00790,map01100,map02010	M00053,M00189,M00240	R00086,R00615,R02094,R02098,R11581	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000,ko03400	3.A.1.14,3.A.1.8	-	-	DUF2478,NTPase_1
TLS3_k127_3921504_2	1480694.DC28_09665	2.606e-100	337.0	COG2222@1|root,COG2222@2|Bacteria	2|Bacteria	M	isomerase activity	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
TLS3_k127_3921504_1	742817.HMPREF9449_01411	5.799e-113	373.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,2FNGN@200643|Bacteroidia,22WUD@171551|Porphyromonadaceae	976|Bacteroidetes	G	glucokinase	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
TLS3_k127_3921504_0	886379.AEWI01000064_gene2321	3.777e-189	605.0	COG1022@1|root,COG1022@2|Bacteria,4NGFQ@976|Bacteroidetes,2FN1X@200643|Bacteroidia,3XJ1E@558415|Marinilabiliaceae	976|Bacteroidetes	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
TLS3_k127_3921504_4	1235813.JCM10003_1367	2.072e-73	253.0	COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,2FM5H@200643|Bacteroidia,4AM6P@815|Bacteroidaceae	976|Bacteroidetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
TLS3_k127_3921504_3	1168034.FH5T_02765	5.217e-76	262.0	2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,2FS5N@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
TLS3_k127_3937497_0	1408473.JHXO01000001_gene2112	0.0	1617.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,2FM5R@200643|Bacteroidia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
TLS3_k127_3944021_10	1121481.AUAS01000005_gene1914	1.068e-46	171.0	COG0698@1|root,COG0698@2|Bacteria,4NP5D@976|Bacteroidetes	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
TLS3_k127_3944021_18	1168289.AJKI01000003_gene2924	3.275e-13	76.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,SH3_3
TLS3_k127_3944021_17	1123057.P872_19775	1.889e-15	79.0	2DP1T@1|root,3306B@2|Bacteria,4NVIV@976|Bacteroidetes,47S6F@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3944021_16	243274.THEMA_06040	3.111e-22	102.0	COG0262@1|root,COG0262@2|Bacteria,2GD7B@200918|Thermotogae	200918|Thermotogae	H	dihydrofolate reductase	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
TLS3_k127_3944021_8	1304885.AUEY01000090_gene2886	6.286e-56	200.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,42RB9@68525|delta/epsilon subdivisions,2WMPE@28221|Deltaproteobacteria,2MJPY@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ferritin-like domain	bfr	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
TLS3_k127_3944021_3	1408473.JHXO01000007_gene872	1.119e-187	597.0	COG1282@1|root,COG1282@2|Bacteria,4NHGZ@976|Bacteroidetes,2FSES@200643|Bacteroidia	976|Bacteroidetes	C	NADP transhydrogenase	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
TLS3_k127_3944021_12	468059.AUHA01000003_gene1894	3.935e-38	144.0	COG3288@1|root,COG3288@2|Bacteria,4NT78@976|Bacteroidetes,1ITS9@117747|Sphingobacteriia	976|Bacteroidetes	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
TLS3_k127_3944021_5	1408473.JHXO01000007_gene870	1.442e-127	418.0	COG3288@1|root,COG3288@2|Bacteria,4NGH1@976|Bacteroidetes,2G2N7@200643|Bacteroidia	976|Bacteroidetes	C	NAD(P)( ) transhydrogenase (AB-specific), alpha subunit	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
TLS3_k127_3944021_2	945713.IALB_0193	2.306e-209	672.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_M14,Peptidase_S9
TLS3_k127_3944021_15	1408473.JHXO01000006_gene1339	4.06e-32	128.0	COG4109@1|root,COG4109@2|Bacteria,4NTDQ@976|Bacteroidetes,2FTXG@200643|Bacteroidia	976|Bacteroidetes	K	DRTGG domain	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
TLS3_k127_3944021_11	1168289.AJKI01000053_gene798	7.734e-46	169.0	COG2172@1|root,COG2172@2|Bacteria,4NRAS@976|Bacteroidetes,2FT57@200643|Bacteroidia,3XK5B@558415|Marinilabiliaceae	976|Bacteroidetes	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2
TLS3_k127_3944021_14	385682.AFSL01000064_gene1710	2.814e-35	137.0	COG4109@1|root,COG4109@2|Bacteria,4NTA0@976|Bacteroidetes,2FTZ6@200643|Bacteroidia,3XKAD@558415|Marinilabiliaceae	976|Bacteroidetes	K	DRTGG domain	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
TLS3_k127_3944021_6	869213.JCM21142_41807	5.374e-73	254.0	COG1379@1|root,COG1379@2|Bacteria,4NP19@976|Bacteroidetes	976|Bacteroidetes	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP,PHP_C
TLS3_k127_3944021_13	1408422.JHYF01000001_gene2900	2.344e-35	141.0	COG3290@1|root,COG3290@2|Bacteria,1UJ85@1239|Firmicutes,25EY1@186801|Clostridia,36UUR@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
TLS3_k127_3944021_9	1123008.KB905715_gene3634	6.92e-53	189.0	COG3411@1|root,COG3411@2|Bacteria,4NQQ2@976|Bacteroidetes,2FTGH@200643|Bacteroidia,22Y5H@171551|Porphyromonadaceae	976|Bacteroidetes	C	Ferredoxin	-	-	1.12.1.3	ko:K17992	-	-	-	-	ko00000,ko01000	-	-	-	-
TLS3_k127_3944021_0	1122931.AUAE01000003_gene256	1.965e-312	964.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,2FN7A@200643|Bacteroidia,22X6V@171551|Porphyromonadaceae	976|Bacteroidetes	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	nuoF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
TLS3_k127_3944021_1	1123008.KB905715_gene3636	9.338e-295	915.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,4PKV4@976|Bacteroidetes,2FNTR@200643|Bacteroidia,22XI7@171551|Porphyromonadaceae	976|Bacteroidetes	C	Iron hydrogenase small subunit	hndD	-	1.12.1.3,1.17.1.9	ko:K00123,ko:K18332	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
TLS3_k127_3944021_7	1123008.KB905715_gene3637	5.828e-66	228.0	COG1905@1|root,COG1905@2|Bacteria,4NHIQ@976|Bacteroidetes,2FNZ6@200643|Bacteroidia,22XW4@171551|Porphyromonadaceae	976|Bacteroidetes	C	Thioredoxin-like [2Fe-2S] ferredoxin	hndA	-	1.12.1.3	ko:K18330	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx
TLS3_k127_3944021_4	742725.HMPREF9450_01669	1.637e-134	436.0	COG1032@1|root,COG1032@2|Bacteria,4NGYA@976|Bacteroidetes,2FKYB@200643|Bacteroidia,22UV2@171550|Rikenellaceae	976|Bacteroidetes	C	Domain of unknown function (DUF3362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
TLS3_k127_3947814_4	886379.AEWI01000005_gene968	1.259e-101	338.0	COG1027@1|root,COG1027@2|Bacteria,4P1PR@976|Bacteroidetes,2FNWI@200643|Bacteroidia,3XKRG@558415|Marinilabiliaceae	976|Bacteroidetes	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
TLS3_k127_3947814_0	886379.AEWI01000005_gene966	4.351e-171	545.0	COG0486@1|root,COG0486@2|Bacteria,4NFU5@976|Bacteroidetes,2FN3B@200643|Bacteroidia,3XJBB@558415|Marinilabiliaceae	976|Bacteroidetes	S	50S ribosome-binding GTPase	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
TLS3_k127_3947814_1	385682.AFSL01000023_gene2131	1.654e-161	546.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,2FM3F@200643|Bacteroidia,3XIKA@558415|Marinilabiliaceae	976|Bacteroidetes	M	MBOAT, membrane-bound O-acyltransferase family	algI	-	-	-	-	-	-	-	-	-	-	-	MBOAT
TLS3_k127_3947814_2	869213.JCM21142_104181	3.973e-152	496.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,47KJK@768503|Cytophagia	976|Bacteroidetes	M	PFAM Transglycosylase SLT domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
TLS3_k127_3947814_8	869213.JCM21142_104182	3.4e-38	151.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,47RVI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3947814_5	1408473.JHXO01000006_gene1177	1.957e-99	332.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,2FP81@200643|Bacteroidia	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
TLS3_k127_3947814_3	1168034.FH5T_09550	2.018e-117	382.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,2FMX2@200643|Bacteroidia	976|Bacteroidetes	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
TLS3_k127_3947814_7	1408473.JHXO01000007_gene777	2.341e-80	278.0	COG1597@1|root,COG1597@2|Bacteria,4NGPY@976|Bacteroidetes,2FP27@200643|Bacteroidia	976|Bacteroidetes	I	lipid kinase, YegS Rv2252 BmrU family	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
TLS3_k127_3947814_6	709991.Odosp_2896	2.674e-83	284.0	COG3823@1|root,COG3823@2|Bacteria,4NF2M@976|Bacteroidetes,2FS7M@200643|Bacteroidia,22ZBV@171551|Porphyromonadaceae	976|Bacteroidetes	O	Glutamine cyclotransferase	-	-	2.3.2.5	ko:K00683	-	-	-	-	ko00000,ko01000	-	-	-	Glu_cyclase_2
TLS3_k127_3952109_0	1408473.JHXO01000011_gene3040	1.989e-118	390.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,2FME3@200643|Bacteroidia	976|Bacteroidetes	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_3952109_1	1237149.C900_01411	2.678e-116	384.0	COG2843@1|root,COG2843@2|Bacteria,4NI6J@976|Bacteroidetes,47NKK@768503|Cytophagia	976|Bacteroidetes	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
TLS3_k127_3952109_2	385682.AFSL01000002_gene1872	3.524e-37	142.0	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,2FTI6@200643|Bacteroidia,3XK3K@558415|Marinilabiliaceae	976|Bacteroidetes	K	helix_turn_helix, mercury resistance	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
TLS3_k127_3952109_3	525373.HMPREF0766_10944	4.865e-35	137.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,1IP4G@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
TLS3_k127_3954359_0	616991.JPOO01000001_gene3208	6.269e-123	404.0	COG1073@1|root,COG1073@2|Bacteria,4NI0B@976|Bacteroidetes	976|Bacteroidetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3954359_1	269798.CHU_0163	1.32e-37	148.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,47K4K@768503|Cytophagia	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
TLS3_k127_3964333_5	1122621.ATZA01000007_gene826	3.404e-51	195.0	COG0642@1|root,COG2205@2|Bacteria,4NISE@976|Bacteroidetes,1J0VW@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_3964333_4	1121007.AUML01000023_gene1169	2.922e-72	250.0	COG0745@1|root,COG0745@2|Bacteria,4NH5Q@976|Bacteroidetes,1I080@117743|Flavobacteriia,2YH73@290174|Aquimarina	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_3964333_2	1408473.JHXO01000004_gene208	3.605e-89	306.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,2FN8N@200643|Bacteroidia	976|Bacteroidetes	CO	AhpC Tsa family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
TLS3_k127_3964333_0	1515613.HQ37_01885	1.265e-132	433.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,2FNHU@200643|Bacteroidia,22XBJ@171551|Porphyromonadaceae	976|Bacteroidetes	E	LAO AO transport system ATPase	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
TLS3_k127_3964333_3	385682.AFSL01000009_gene2469	6.241e-89	305.0	2CG1Y@1|root,2Z9QX@2|Bacteria,4NJI6@976|Bacteroidetes,2FPRX@200643|Bacteroidia,3XJ2E@558415|Marinilabiliaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
TLS3_k127_3964333_1	1408433.JHXV01000010_gene496	5.152e-111	384.0	COG4775@1|root,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1I8E9@117743|Flavobacteriia,2PBCC@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM WD40-like beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_3987348_5	400682.PAC_15710868	1.469e-59	225.0	COG0666@1|root,KOG4369@1|root,KOG0504@2759|Eukaryota,KOG0514@2759|Eukaryota,KOG4177@2759|Eukaryota,KOG4369@2759|Eukaryota,38BVK@33154|Opisthokonta	33154|Opisthokonta	M	protein localization to T-tubule	-	-	-	ko:K10380,ko:K15503,ko:K21440	ko04624,ko05205,map04624,map05205	-	-	-	ko00000,ko00001,ko01009,ko03400,ko04131,ko04812	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
TLS3_k127_3987348_0	926559.JoomaDRAFT_0554	1.215e-127	413.0	COG3384@1|root,COG3384@2|Bacteria,4NFGT@976|Bacteroidetes,1HX1P@117743|Flavobacteriia	976|Bacteroidetes	S	in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
TLS3_k127_3987348_4	1408473.JHXO01000012_gene293	5.169e-78	263.0	COG2353@1|root,COG2353@2|Bacteria,4NNMD@976|Bacteroidetes,2FVBK@200643|Bacteroidia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_3987348_1	1249975.JQLP01000005_gene2532	1.159e-116	381.0	COG2207@1|root,COG2207@2|Bacteria,4NMRA@976|Bacteroidetes,1HZG1@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
TLS3_k127_3987348_7	1185876.BN8_01081	9.811e-14	77.0	2E5B2@1|root,33036@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3987348_6	385682.AFSL01000003_gene1912	6.068e-18	88.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,2G24U@200643|Bacteroidia,3XK3Q@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
TLS3_k127_3987348_3	1220534.B655_0947	1.967e-96	344.0	arCOG02377@1|root,arCOG03931@1|root,arCOG07605@1|root,arCOG02377@2157|Archaea,arCOG03931@2157|Archaea,arCOG07605@2157|Archaea,2Y7PW@28890|Euryarchaeota	28890|Euryarchaeota	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
TLS3_k127_3987348_8	877455.Metbo_1454	0.0007259	45.0	COG3945@1|root,arCOG01471@2157|Archaea	2157|Archaea	S	Hemerythrin HHE cation binding	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
TLS3_k127_3987348_2	925409.KI911562_gene1591	2.573e-101	334.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IRBB@117747|Sphingobacteriia	976|Bacteroidetes	I	SPTR Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
TLS3_k127_3992659_2	1408473.JHXO01000009_gene3374	2.16e-99	336.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,4NEV7@976|Bacteroidetes,2FKZX@200643|Bacteroidia	976|Bacteroidetes	J	NOL1 NOP2 sun family protein	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA
TLS3_k127_3992659_0	709991.Odosp_3390	5.572e-280	881.0	COG3534@1|root,COG3534@2|Bacteria,4NHR5@976|Bacteroidetes,2G2XU@200643|Bacteroidia,231K5@171551|Porphyromonadaceae	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
TLS3_k127_3992659_1	1519464.HY22_09440	2.152e-171	550.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
TLS3_k127_3992659_3	1121403.AUCV01000022_gene3515	1.323e-12	72.0	COG3385@1|root,COG3385@2|Bacteria,1NM1J@1224|Proteobacteria	1224|Proteobacteria	L	similarity to EGAD 8624	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
TLS3_k127_3995351_2	485917.Phep_0811	3.472e-48	178.0	COG3828@1|root,COG3828@2|Bacteria,4NRZF@976|Bacteroidetes,1IVGZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
TLS3_k127_3995351_1	1340493.JNIF01000004_gene1025	1.847e-93	332.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	PKD,PPC,Peptidase_M10,Peptidase_M28,SLH
TLS3_k127_3995351_0	1408473.JHXO01000006_gene1038	3.107e-190	599.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,2FM0G@200643|Bacteroidia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
TLS3_k127_4017700_4	411479.BACUNI_01365	5.716e-22	96.0	COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,2FN0P@200643|Bacteroidia,4AKPQ@815|Bacteroidaceae	976|Bacteroidetes	H	Belongs to the transketolase family	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
TLS3_k127_4017700_3	1168034.FH5T_14110	3.607e-53	193.0	COG0637@1|root,COG0637@2|Bacteria,4NEEH@976|Bacteroidetes,2FXP5@200643|Bacteroidia	976|Bacteroidetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
TLS3_k127_4017700_0	1168034.FH5T_04620	2.559e-91	309.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes	976|Bacteroidetes	G	Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_4017700_1	1122971.BAME01000013_gene1614	1.382e-67	238.0	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,2FM5I@200643|Bacteroidia,22XPJ@171551|Porphyromonadaceae	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
TLS3_k127_4017700_2	1232410.KI421421_gene3694	8.941e-54	197.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria,43SHI@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
TLS3_k127_4017700_5	1121129.KB903359_gene1508	1.073e-08	57.0	COG0652@1|root,COG0652@2|Bacteria,4NKQ7@976|Bacteroidetes,2FSSH@200643|Bacteroidia,23095@171551|Porphyromonadaceae	976|Bacteroidetes	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
TLS3_k127_4049979_3	927658.AJUM01000047_gene2778	1.889e-06	57.0	28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,2G1ZT@200643|Bacteroidia,3XIMW@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4049979_0	762968.HMPREF9441_00618	1.456e-93	313.0	COG0149@1|root,COG2259@1|root,COG0149@2|Bacteria,COG2259@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
TLS3_k127_4049979_1	1121101.HMPREF1532_03939	2.122e-92	316.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,2G2Z3@200643|Bacteroidia,4APDA@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
TLS3_k127_4049979_2	1501391.LG35_03125	9.212e-57	202.0	COG0125@1|root,COG0125@2|Bacteria,4NPI5@976|Bacteroidetes,2G1QI@200643|Bacteroidia,22UC8@171550|Rikenellaceae	976|Bacteroidetes	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
TLS3_k127_4092623_1	1254432.SCE1572_43355	2.402e-28	119.0	28ZS2@1|root,2ZMGV@2|Bacteria,1Q9PN@1224|Proteobacteria,434I5@68525|delta/epsilon subdivisions,2X8WM@28221|Deltaproteobacteria,2Z0QQ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CAP
TLS3_k127_4092623_0	1185653.A1A1_05222	2.9e-57	208.0	COG0702@1|root,COG0702@2|Bacteria,1V112@1239|Firmicutes,4HEVN@91061|Bacilli,26F8G@186818|Planococcaceae	91061|Bacilli	GM	Nucleoside-diphosphate-sugar epimerases	M1-688	-	-	-	-	-	-	-	-	-	-	-	Epimerase,HIM1,NAD_binding_10
TLS3_k127_4098214_1	1191523.MROS_0147	1.941e-196	623.0	COG4885@1|root,COG4885@2|Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,Cytochrome_C554
TLS3_k127_4098214_3	867900.Celly_0463	4.202e-152	491.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,1HXRR@117743|Flavobacteriia,1F8Y6@104264|Cellulophaga	976|Bacteroidetes	H	PFAM FAD binding domain of DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
TLS3_k127_4098214_0	694427.Palpr_0031	1.001e-210	672.0	COG1307@1|root,COG1461@1|root,COG1307@2|Bacteria,COG1461@2|Bacteria,4NXDG@976|Bacteroidetes,2FUZ2@200643|Bacteroidia	976|Bacteroidetes	S	Dihydroxyacetone kinase family	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak2,DegV
TLS3_k127_4098214_4	694427.Palpr_0030	1.056e-100	334.0	COG3752@1|root,COG3752@2|Bacteria,4NJXA@976|Bacteroidetes,2FWRU@200643|Bacteroidia	976|Bacteroidetes	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
TLS3_k127_4098214_2	278957.ABEA03000041_gene2046	1.908e-156	513.0	COG3250@1|root,COG3250@2|Bacteria,46YAN@74201|Verrucomicrobia,3K989@414999|Opitutae	414999|Opitutae	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_410037_5	1168034.FH5T_12510	4.929e-13	73.0	2E9C0@1|root,333JQ@2|Bacteria,4NVAR@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_410037_1	1408473.JHXO01000001_gene2472	3.076e-73	255.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,2FMR1@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
TLS3_k127_410037_4	1121129.KB903360_gene3112	3.608e-32	132.0	COG3117@1|root,COG3117@2|Bacteria,4NSXY@976|Bacteroidetes,2G2BC@200643|Bacteroidia,231VX@171551|Porphyromonadaceae	976|Bacteroidetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
TLS3_k127_410037_3	997353.HMPREF9144_1262	6.599e-50	194.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,2FN33@200643|Bacteroidia	976|Bacteroidetes	I	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
TLS3_k127_410037_2	385682.AFSL01000082_gene1177	1.728e-57	208.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,2FMPK@200643|Bacteroidia,3XJ75@558415|Marinilabiliaceae	976|Bacteroidetes	K	Type III pantothenate kinase	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
TLS3_k127_410037_0	869213.JCM21142_104098	7.111e-185	588.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,47K49@768503|Cytophagia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
TLS3_k127_4102105_1	1408473.JHXO01000006_gene1072	3.709e-82	276.0	COG1060@1|root,COG1060@2|Bacteria,4NGDN@976|Bacteroidetes,2FWUF@200643|Bacteroidia	976|Bacteroidetes	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
TLS3_k127_4102105_3	886379.AEWI01000030_gene298	6.241e-60	218.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,2FPS4@200643|Bacteroidia,3XJ68@558415|Marinilabiliaceae	976|Bacteroidetes	S	PASTA	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
TLS3_k127_4102105_2	1453500.AT05_08370	1.213e-66	250.0	28M1N@1|root,2ZAGE@2|Bacteria,4NIDD@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4102105_0	927658.AJUM01000034_gene137	6.625e-154	492.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,2FMD1@200643|Bacteroidia,3XJJR@558415|Marinilabiliaceae	976|Bacteroidetes	J	S4 RNA-binding domain	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS3_k127_4102105_4	1168289.AJKI01000031_gene1022	1.27e-09	63.0	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,2FN0H@200643|Bacteroidia,3XJPS@558415|Marinilabiliaceae	976|Bacteroidetes	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
TLS3_k127_4106683_11	868131.MSWAN_2151	3.267e-22	96.0	COG0369@1|root,COG1773@1|root,arCOG02430@2157|Archaea,arCOG04391@2157|Archaea,2XV44@28890|Euryarchaeota,23NS7@183925|Methanobacteria	183925|Methanobacteria	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane,Rubredoxin
TLS3_k127_4106683_0	1408473.JHXO01000012_gene338	3.543e-228	716.0	COG3051@1|root,COG3051@2|Bacteria,4NJUR@976|Bacteroidetes,2FRJJ@200643|Bacteroidia	976|Bacteroidetes	C	Citrate lyase, alpha subunit (CitF)	citF	-	-	-	-	-	-	-	-	-	-	-	CitF
TLS3_k127_4106683_2	1499967.BAYZ01000139_gene150	1.36e-145	471.0	COG2301@1|root,COG3052@1|root,COG2301@2|Bacteria,COG3052@2|Bacteria,2NQDZ@2323|unclassified Bacteria	2|Bacteria	G	HpcH/HpaI aldolase/citrate lyase family	citD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008815,GO:0009346,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016833,GO:0032991,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	4.1.3.25,4.1.3.34	ko:K01644,ko:K01646,ko:K18292	ko00660,ko01100,ko02020,map00660,map01100,map02020	-	R00237,R00362	RC00067,RC00502,RC01118,RC01205	ko00000,ko00001,ko01000	-	-	-	ACP,HpcH_HpaI
TLS3_k127_4106683_9	1121904.ARBP01000026_gene670	4.76e-62	216.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,47PQ6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
TLS3_k127_4106683_1	1408473.JHXO01000010_gene3660	4.536e-155	505.0	COG0348@1|root,COG0437@1|root,COG0348@2|Bacteria,COG0437@2|Bacteria,4NHSX@976|Bacteroidetes,2FN5F@200643|Bacteroidia	976|Bacteroidetes	C	Psort location CytoplasmicMembrane, score	yccM_2	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7,Fer4_9
TLS3_k127_4106683_5	1408473.JHXO01000010_gene3661	1.085e-109	362.0	COG2006@1|root,COG2006@2|Bacteria,4NH1F@976|Bacteroidetes,2FP1X@200643|Bacteroidia	976|Bacteroidetes	S	Tat pathway signal sequence domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,TAT_signal
TLS3_k127_4106683_4	1230342.CTM_03424	3.925e-132	432.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,36DW1@31979|Clostridiaceae	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
TLS3_k127_4106683_7	1487921.DP68_00285	6.942e-74	257.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,36DE3@31979|Clostridiaceae	186801|Clostridia	S	TIGRFAM TIGR00268 family protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
TLS3_k127_4106683_6	332101.JIBU02000039_gene1687	1.033e-100	333.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,36F1K@31979|Clostridiaceae	186801|Clostridia	S	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
TLS3_k127_4106683_10	1227276.HMPREF9148_02228	6.183e-39	152.0	COG0224@1|root,COG0224@2|Bacteria,4NM5H@976|Bacteroidetes,2FNPU@200643|Bacteroidia	976|Bacteroidetes	C	WbqC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
TLS3_k127_4106683_8	1121129.KB903359_gene1899	2.547e-71	259.0	COG2067@1|root,COG2067@2|Bacteria,4NFS7@976|Bacteroidetes,2FM7S@200643|Bacteroidia,22WCW@171551|Porphyromonadaceae	976|Bacteroidetes	I	Outer membrane protein transport protein, Ompp1 FadL TodX	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
TLS3_k127_4106683_12	1408473.JHXO01000013_gene535	6.475e-13	81.0	2DM3I@1|root,31JQ3@2|Bacteria,4NRM4@976|Bacteroidetes,2FM1R@200643|Bacteroidia	976|Bacteroidetes	S	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4106683_13	1121957.ATVL01000011_gene3915	6.978e-09	66.0	2CJG0@1|root,332HN@2|Bacteria,4NVWF@976|Bacteroidetes,47SVM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4106683_3	1408473.JHXO01000013_gene536	4.159e-134	429.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,2FMZT@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
TLS3_k127_4107282_8	485917.Phep_0187	1.015e-56	206.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,1IP2T@117747|Sphingobacteriia	976|Bacteroidetes	P	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
TLS3_k127_4107282_9	1270196.JCKI01000001_gene3850	2.755e-48	179.0	COG1595@1|root,COG1595@2|Bacteria,4NNEM@976|Bacteroidetes,1IRWR@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_4107282_11	485917.Phep_0189	4.659e-27	125.0	COG0810@1|root,COG0810@2|Bacteria,4P9NE@976|Bacteroidetes,1IXF7@117747|Sphingobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_4107282_4	926549.KI421517_gene3281	2.553e-137	445.0	COG4641@1|root,COG4641@2|Bacteria,4NKD0@976|Bacteroidetes,47UCV@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
TLS3_k127_4107282_3	661478.OP10G_3318	5.177e-144	464.0	COG4641@1|root,COG4641@2|Bacteria	2|Bacteria	M	Protein conserved in bacteria	ykvP	-	-	-	-	-	-	-	-	-	-	-	DUF3880,Glyco_trans_1_2,Glyco_trans_1_4,Glycos_transf_2
TLS3_k127_4107282_2	1124780.ANNU01000074_gene737	6.324e-147	475.0	COG4641@1|root,COG4641@2|Bacteria,4NJZM@976|Bacteroidetes,47KRV@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
TLS3_k127_4107282_7	926549.KI421517_gene3278	4.062e-89	306.0	COG0438@1|root,COG0438@2|Bacteria,4NFGV@976|Bacteroidetes,47T96@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_4107282_6	1123060.JONP01000005_gene5609	4.844e-102	342.0	COG0673@1|root,COG0673@2|Bacteria,1NKUI@1224|Proteobacteria,2TUGN@28211|Alphaproteobacteria,2JV8M@204441|Rhodospirillales	204441|Rhodospirillales	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_4107282_5	926549.KI421517_gene3276	8.639e-111	366.0	COG1063@1|root,COG1063@2|Bacteria,4NEDC@976|Bacteroidetes,47TZI@768503|Cytophagia	976|Bacteroidetes	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.103,1.1.1.14,1.1.1.303,1.1.1.4	ko:K00004,ko:K00008,ko:K00060	ko00040,ko00051,ko00260,ko00650,ko01100,map00040,map00051,map00260,map00650,map01100	M00014	R00875,R01465,R01896,R02855,R02946,R10504	RC00085,RC00102,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_4107282_0	1237149.C900_05414	4.275e-234	741.0	COG0451@1|root,COG0451@2|Bacteria,4NDX8@976|Bacteroidetes,47UAC@768503|Cytophagia	976|Bacteroidetes	GM	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
TLS3_k127_4107282_1	1123234.AUKI01000017_gene2622	1.319e-153	493.0	COG0451@1|root,COG0451@2|Bacteria,4NIBV@976|Bacteroidetes,1I77F@117743|Flavobacteriia	976|Bacteroidetes	M	Male sterility protein	-	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
TLS3_k127_4107282_10	880526.KE386488_gene1278	9.471e-45	173.0	COG3669@1|root,COG3934@1|root,COG3669@2|Bacteria,COG3934@2|Bacteria,4NZYV@976|Bacteroidetes,2FWVF@200643|Bacteroidia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4165750_2	694427.Palpr_1465	5.563e-18	83.0	COG0370@1|root,COG1918@1|root,COG0370@2|Bacteria,COG1918@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia,22VWF@171551|Porphyromonadaceae	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
TLS3_k127_4165750_0	1121898.Q766_10440	2.776e-242	764.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFBK@976|Bacteroidetes,1HY8A@117743|Flavobacteriia,2NUMJ@237|Flavobacterium	976|Bacteroidetes	EU	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
TLS3_k127_4165750_1	697281.Mahau_1207	2.919e-50	199.0	COG2730@1|root,COG2730@2|Bacteria,1V9GI@1239|Firmicutes,24KYA@186801|Clostridia	186801|Clostridia	G	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
TLS3_k127_4171575_0	1408473.JHXO01000007_gene752	4.255e-62	235.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,4NGZ0@976|Bacteroidetes	976|Bacteroidetes	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9
TLS3_k127_4171575_1	1121405.dsmv_1129	1.408e-44	182.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2X734@28221|Deltaproteobacteria,2MIC0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
TLS3_k127_4185004_2	1408473.JHXO01000004_gene169	6.124e-53	188.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,2FM07@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
TLS3_k127_4185004_5	694427.Palpr_2638	4.891e-17	85.0	COG2204@1|root,COG2204@2|Bacteria,4NR03@976|Bacteroidetes	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_4185004_3	1408473.JHXO01000004_gene163	7.772e-44	171.0	COG0810@1|root,COG0810@2|Bacteria,4NG4I@976|Bacteroidetes,2FM9A@200643|Bacteroidia	976|Bacteroidetes	M	TonB family domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
TLS3_k127_4185004_4	1168289.AJKI01000065_gene3750	6.402e-39	148.0	COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,2FRY4@200643|Bacteroidia,3XK5Q@558415|Marinilabiliaceae	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
TLS3_k127_4185004_1	886379.AEWI01000010_gene612	7.062e-85	286.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,2FNG0@200643|Bacteroidia,3XIUJ@558415|Marinilabiliaceae	976|Bacteroidetes	U	MotA/TolQ/ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
TLS3_k127_4185004_0	1408473.JHXO01000004_gene166	7.43e-99	337.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,2FNBJ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location OuterMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	TamB
TLS3_k127_4187833_4	886379.AEWI01000004_gene879	1.694e-53	194.0	COG1940@1|root,COG1940@2|Bacteria,4NM8T@976|Bacteroidetes,2FSJS@200643|Bacteroidia,3XKR2@558415|Marinilabiliaceae	976|Bacteroidetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
TLS3_k127_4187833_1	1168034.FH5T_21730	4.997e-192	608.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,2FM2T@200643|Bacteroidia	976|Bacteroidetes	C	Psort location Cytoplasmic, score	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
TLS3_k127_4187833_5	1408473.JHXO01000004_gene39	1.154e-28	124.0	COG1102@1|root,COG1102@2|Bacteria,4NU66@976|Bacteroidetes	976|Bacteroidetes	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
TLS3_k127_4187833_7	1408473.JHXO01000009_gene3263	7.021e-20	96.0	2FFU4@1|root,347R8@2|Bacteria,4P5R2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4187833_6	926549.KI421517_gene3115	5.995e-25	109.0	COG1585@1|root,COG1585@2|Bacteria,4NV00@976|Bacteroidetes,47S1M@768503|Cytophagia	976|Bacteroidetes	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
TLS3_k127_4187833_2	509635.N824_12640	1.141e-132	429.0	COG0330@1|root,COG0330@2|Bacteria,4NEP5@976|Bacteroidetes,1IX6I@117747|Sphingobacteriia	976|Bacteroidetes	O	C-terminal region of band_7	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
TLS3_k127_4187833_0	709991.Odosp_3648	0.0	1131.0	COG1882@1|root,COG1882@2|Bacteria,4NDWW@976|Bacteroidetes,2FMC2@200643|Bacteroidia,22WNW@171551|Porphyromonadaceae	976|Bacteroidetes	C	Pyruvate formate lyase-like	-	-	2.3.1.54,4.1.1.83	ko:K00656,ko:K18427	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
TLS3_k127_4187833_3	522772.Dacet_1515	2.238e-67	238.0	COG1180@1|root,COG1180@2|Bacteria,2GFJN@200930|Deferribacteres	200930|Deferribacteres	C	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
TLS3_k127_426740_2	742726.HMPREF9448_02737	4.397e-36	141.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes,2FNB7@200643|Bacteroidia,22X71@171551|Porphyromonadaceae	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
TLS3_k127_426740_0	1408473.JHXO01000007_gene986	3.683e-224	709.0	COG5492@1|root,COG5492@2|Bacteria,4NEAB@976|Bacteroidetes	976|Bacteroidetes	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
TLS3_k127_426740_1	1123508.JH636448_gene7659	2.528e-192	609.0	COG2730@1|root,COG2730@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
TLS3_k127_4293379_1	1303518.CCALI_00896	2.492e-31	137.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
TLS3_k127_4293379_0	1408473.JHXO01000012_gene420	4.844e-78	263.0	COG2010@1|root,COG2010@2|Bacteria,4PN3J@976|Bacteroidetes	976|Bacteroidetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_4363265_3	1168034.FH5T_01635	1.681e-102	354.0	COG0226@1|root,COG0509@1|root,COG0226@2|Bacteria,COG0509@2|Bacteria	2|Bacteria	E	glycine decarboxylation via glycine cleavage system	gcvH	-	-	ko:K02040,ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,ko02010,ko02020,ko05152,map00260,map00630,map01100,map01110,map01130,map01200,map02010,map02020,map05152	M00222,M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	GCV_H,PBP_like_2
TLS3_k127_4363265_1	1168034.FH5T_01615	8.598e-205	651.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,2FR1C@200643|Bacteroidia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_4363265_0	1168034.FH5T_01610	1.343e-212	667.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FMPG@200643|Bacteroidia	976|Bacteroidetes	T	acetoacetate metabolism regulatory protein AtoC K07714	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_4363265_4	1168034.FH5T_01605	2.327e-45	170.0	COG1913@1|root,COG1913@2|Bacteria,4NMI8@976|Bacteroidetes	976|Bacteroidetes	S	Zn-dependent protease	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
TLS3_k127_4363265_5	1121403.AUCV01000010_gene1368	3.664e-33	132.0	COG2204@1|root,COG2204@2|Bacteria,1QW8K@1224|Proteobacteria,42V8F@68525|delta/epsilon subdivisions,2WRMW@28221|Deltaproteobacteria,2MNUV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_4363265_2	439235.Dalk_1072	1.149e-107	364.0	COG0784@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MJ2F@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
TLS3_k127_4375017_6	1348583.ATLH01000013_gene2817	1.295e-72	250.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1HX85@117743|Flavobacteriia,1F7QM@104264|Cellulophaga	976|Bacteroidetes	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_4375017_4	1121904.ARBP01000016_gene5221	8.604e-120	399.0	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,47M6X@768503|Cytophagia	976|Bacteroidetes	Q	PFAM Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_4375017_1	1408473.JHXO01000011_gene3059	2.077e-134	437.0	COG0438@1|root,COG0438@2|Bacteria,4NEZI@976|Bacteroidetes,2FQFD@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_4375017_2	1121129.KB903367_gene2764	2.036e-130	425.0	COG0463@1|root,COG0463@2|Bacteria,4NEVT@976|Bacteroidetes,2FMV7@200643|Bacteroidia,22WFA@171551|Porphyromonadaceae	976|Bacteroidetes	M	glycosyl transferase family 2	arnC	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_4375017_7	553177.CAPSP0001_1529	6.677e-11	70.0	2DM6B@1|root,31WK9@2|Bacteria,4NQK1@976|Bacteroidetes,1I2ZA@117743|Flavobacteriia,1ERWF@1016|Capnocytophaga	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
TLS3_k127_4375017_5	1408473.JHXO01000005_gene1460	6.546e-82	278.0	COG0009@1|root,COG0009@2|Bacteria,4NDZR@976|Bacteroidetes,2FP9A@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
TLS3_k127_4375017_3	869213.JCM21142_41627	1.261e-123	413.0	COG0168@1|root,COG0168@2|Bacteria,4NGMF@976|Bacteroidetes,47JH5@768503|Cytophagia	976|Bacteroidetes	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
TLS3_k127_4375017_0	927658.AJUM01000042_gene1504	8.391e-142	462.0	COG0569@1|root,COG0569@2|Bacteria,4NE31@976|Bacteroidetes,2FP1F@200643|Bacteroidia,3XJ7G@558415|Marinilabiliaceae	976|Bacteroidetes	P	TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
TLS3_k127_437566_4	1122985.HMPREF1991_00150	5.509e-10	65.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,2FQ63@200643|Bacteroidia	976|Bacteroidetes	M	outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
TLS3_k127_437566_0	385682.AFSL01000074_gene1274	1.319e-241	770.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,2FMX0@200643|Bacteroidia,3XJC7@558415|Marinilabiliaceae	976|Bacteroidetes	D	Ftsk_gamma	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
TLS3_k127_437566_5	755732.Fluta_0518	1.224e-06	58.0	2A8FU@1|root,30XHS@2|Bacteria,4PAYV@976|Bacteroidetes,1ICSJ@117743|Flavobacteriia,2PC02@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_437566_2	1121129.KB903367_gene2648	6.278e-147	471.0	COG0549@1|root,COG0549@2|Bacteria,4NITW@976|Bacteroidetes,2FNTV@200643|Bacteroidia,22ZFV@171551|Porphyromonadaceae	976|Bacteroidetes	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
TLS3_k127_437566_1	1408473.JHXO01000004_gene100	4.535e-168	535.0	COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,2FPNE@200643|Bacteroidia	976|Bacteroidetes	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
TLS3_k127_437566_3	1168289.AJKI01000002_gene2582	2.489e-13	71.0	COG2839@1|root,COG2839@2|Bacteria,4NNIY@976|Bacteroidetes,2FS52@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
TLS3_k127_4400213_1	1408473.JHXO01000004_gene169	1.232e-163	518.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,2FM07@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
TLS3_k127_4400213_0	886379.AEWI01000010_gene606	5.005e-208	662.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,4NFCF@976|Bacteroidetes,2FNDY@200643|Bacteroidia,3XIVN@558415|Marinilabiliaceae	976|Bacteroidetes	P	Voltage gated chloride channel	clcB	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
TLS3_k127_441901_2	1408473.JHXO01000009_gene3407	1.183e-164	525.0	COG0019@1|root,COG0019@2|Bacteria,4NEN0@976|Bacteroidetes,2FNN3@200643|Bacteroidia	976|Bacteroidetes	E	carboxynorspermidine decarboxylase	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS3_k127_441901_1	927658.AJUM01000044_gene651	1.423e-241	749.0	COG1748@1|root,COG1748@2|Bacteria,4NE0Y@976|Bacteroidetes,2FMKT@200643|Bacteroidia,3XJ9G@558415|Marinilabiliaceae	976|Bacteroidetes	E	Saccharopine dehydrogenase C-terminal domain	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
TLS3_k127_441901_4	1408473.JHXO01000005_gene1759	7.07e-61	218.0	COG1208@1|root,COG1208@2|Bacteria,4NMJ5@976|Bacteroidetes,2FNEE@200643|Bacteroidia	976|Bacteroidetes	JM	Nucleotidyl transferase	hddC	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
TLS3_k127_441901_3	886379.AEWI01000024_gene378	4.987e-92	313.0	COG1660@1|root,COG3178@1|root,COG1660@2|Bacteria,COG3178@2|Bacteria,4NIT0@976|Bacteroidetes,2FMEM@200643|Bacteroidia,3XJI6@558415|Marinilabiliaceae	976|Bacteroidetes	S	P-loop ATPase protein family	-	-	-	-	-	-	-	-	-	-	-	-	APH,ATP_bind_2
TLS3_k127_441901_0	926556.Echvi_3893	1.187e-307	960.0	COG0363@1|root,COG0363@2|Bacteria,4NDUN@976|Bacteroidetes,47KPX@768503|Cytophagia	976|Bacteroidetes	G	Glucosamine-6-phosphate isomerase	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	PIG-L
TLS3_k127_4441931_0	1220534.B655_0947	2.586e-85	295.0	arCOG02377@1|root,arCOG03931@1|root,arCOG07605@1|root,arCOG02377@2157|Archaea,arCOG03931@2157|Archaea,arCOG07605@2157|Archaea,2Y7PW@28890|Euryarchaeota	28890|Euryarchaeota	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
TLS3_k127_4441931_1	1124780.ANNU01000005_gene2459	6.872e-64	229.0	COG1196@1|root,COG1196@2|Bacteria,4NQBT@976|Bacteroidetes,47QIP@768503|Cytophagia	976|Bacteroidetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4441931_3	746697.Aeqsu_2760	0.0001524	53.0	2BTQM@1|root,32NXS@2|Bacteria,4PFK3@976|Bacteroidetes,1I7AQ@117743|Flavobacteriia	976|Bacteroidetes	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
TLS3_k127_4441931_2	143224.JQMD01000002_gene955	3.193e-18	97.0	COG2207@1|root,COG3063@1|root,COG5616@1|root,COG2207@2|Bacteria,COG3063@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,TPR_2,TPR_8
TLS3_k127_4454919_7	927658.AJUM01000037_gene1834	1.526e-49	181.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
TLS3_k127_4454919_4	471854.Dfer_0193	1.294e-162	517.0	COG3507@1|root,COG3507@2|Bacteria,4NEIZ@976|Bacteroidetes,47NFQ@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
TLS3_k127_4454919_2	616991.JPOO01000003_gene73	7.187e-174	554.0	COG0673@1|root,COG0673@2|Bacteria,4NGTW@976|Bacteroidetes,1I164@117743|Flavobacteriia,23IAD@178469|Arenibacter	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_4454919_5	1235803.C825_05026	1.853e-72	247.0	COG2193@1|root,COG2193@2|Bacteria,4NPMH@976|Bacteroidetes,2FT1G@200643|Bacteroidia,22Y1Z@171551|Porphyromonadaceae	976|Bacteroidetes	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
TLS3_k127_4454919_3	1237149.C900_04915	8.929e-167	537.0	COG3291@1|root,COG3291@2|Bacteria,4PKU5@976|Bacteroidetes,47UGF@768503|Cytophagia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4454919_0	1408433.JHXV01000007_gene2854	0.0	1140.0	COG1629@1|root,COG1629@2|Bacteria,4PKRK@976|Bacteroidetes,1IJDQ@117743|Flavobacteriia,2PAP8@246874|Cryomorphaceae	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
TLS3_k127_4454919_1	867900.Celly_1685	4.494e-281	885.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1HX6P@117743|Flavobacteriia,1FABD@104264|Cellulophaga	976|Bacteroidetes	M	COGs COG4771 Outer membrane receptor for ferrienterochelin and colicins	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_4454919_6	1353276.JADR01000002_gene2076	1.387e-71	247.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,1HXI2@117743|Flavobacteriia	976|Bacteroidetes	K	dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
TLS3_k127_4454919_8	926562.Oweho_0806	1.224e-40	155.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,1I4BI@117743|Flavobacteriia,2PBSI@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_4477183_5	657309.BXY_04740	4.458e-56	200.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,2FKZZ@200643|Bacteroidia,4AKM9@815|Bacteroidaceae	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
TLS3_k127_4477183_8	1313421.JHBV01000043_gene3162	1.554e-14	81.0	2A96C@1|root,30YAY@2|Bacteria,4PCJY@976|Bacteroidetes,1IZIN@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4477183_2	1286632.P278_13700	6.425e-100	333.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1HXYS@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
TLS3_k127_4477183_0	1168034.FH5T_18730	0.0	1560.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,2FMVF@200643|Bacteroidia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
TLS3_k127_4477183_3	869213.JCM21142_93561	2.723e-66	229.0	COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,47Q0N@768503|Cytophagia	976|Bacteroidetes	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
TLS3_k127_4477183_1	714943.Mucpa_1900	4.793e-169	549.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1IQ35@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
TLS3_k127_4477183_7	742725.HMPREF9450_01641	2.822e-46	169.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,2FSHK@200643|Bacteroidia,22UI3@171550|Rikenellaceae	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
TLS3_k127_4477183_6	869213.JCM21142_42072	1.809e-46	168.0	COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,47R23@768503|Cytophagia	976|Bacteroidetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
TLS3_k127_4477183_4	1121129.KB903359_gene1561	4.259e-56	199.0	COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,2FSTU@200643|Bacteroidia,22XP0@171551|Porphyromonadaceae	976|Bacteroidetes	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
TLS3_k127_4483260_2	743722.Sph21_1223	2.811e-57	204.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1IQJT@117747|Sphingobacteriia	976|Bacteroidetes	V	Mate efflux family protein	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
TLS3_k127_4483260_3	858215.Thexy_2120	4.791e-20	100.0	COG1277@1|root,COG1277@2|Bacteria,1TRD6@1239|Firmicutes,24DIY@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
TLS3_k127_4483260_0	1094508.Tsac_0247	2.592e-96	323.0	COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,24941@186801|Clostridia	186801|Clostridia	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_4483260_1	1185876.BN8_00878	2.349e-58	216.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_44910_1	226186.BT_3858	2.449e-82	286.0	COG3537@1|root,COG3537@2|Bacteria,4NI5B@976|Bacteroidetes,2FMQ3@200643|Bacteroidia,4AKKJ@815|Bacteroidaceae	976|Bacteroidetes	G	cog cog3537	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
TLS3_k127_44910_0	1408473.JHXO01000006_gene1340	5.641e-107	356.0	COG0167@1|root,COG0167@2|Bacteria,4NJVM@976|Bacteroidetes,2FR3A@200643|Bacteroidia	976|Bacteroidetes	F	Dihydroorotate dehydrogenase	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
TLS3_k127_4506461_12	1168034.FH5T_01700	5.303e-09	58.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes	976|Bacteroidetes	E	Saccharopine dehydrogenase	-	-	1.5.1.10	ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R02315	RC00215,RC00225	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
TLS3_k127_4506461_5	679937.Bcop_1433	1.032e-57	208.0	COG4123@1|root,COG4123@2|Bacteria,4NG1X@976|Bacteroidetes,2FMHH@200643|Bacteroidia,4AN81@815|Bacteroidaceae	976|Bacteroidetes	J	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	smtA	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
TLS3_k127_4506461_0	1492737.FEM08_34250	5.699e-295	925.0	COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes,1HXGZ@117743|Flavobacteriia	976|Bacteroidetes	G	Pfam Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
TLS3_k127_4506461_11	1227497.C491_04851	4.456e-12	77.0	COG0726@1|root,arCOG04934@2157|Archaea,2XX15@28890|Euryarchaeota,23VFF@183963|Halobacteria	183963|Halobacteria	G	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4506461_3	1237149.C900_02477	2.3e-68	249.0	COG0642@1|root,COG2205@2|Bacteria,4NEIS@976|Bacteroidetes,47N2J@768503|Cytophagia	976|Bacteroidetes	T	signal transduction histidine kinase	arlS_1	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_4506461_2	1123276.KB893313_gene3926	1.933e-72	252.0	COG0745@1|root,COG0745@2|Bacteria,4NE77@976|Bacteroidetes,47K3Z@768503|Cytophagia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_4506461_10	926562.Oweho_2066	2.941e-20	101.0	COG3074@1|root,COG3074@2|Bacteria	2|Bacteria	D	FtsZ-dependent cytokinesis	zapB	GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044424,GO:0044444,GO:0044464,GO:0051301	2.1.1.80,3.1.1.61	ko:K09892,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko03036	-	-	-	ZapB
TLS3_k127_4506461_1	694427.Palpr_2847	8.92e-97	325.0	COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,2G38E@200643|Bacteroidia,2320R@171551|Porphyromonadaceae	976|Bacteroidetes	N	COGs COG1360 Flagellar motor protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
TLS3_k127_4506461_8	1123035.ARLA01000023_gene1141	3.364e-42	163.0	2C7ZG@1|root,332PG@2|Bacteria,4NWXZ@976|Bacteroidetes,1I8I8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4506461_13	869213.JCM21142_94000	0.0004226	45.0	COG1680@1|root,COG1680@2|Bacteria,4NHVF@976|Bacteroidetes,47PGQ@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3887
TLS3_k127_4506461_9	1408473.JHXO01000012_gene413	1.555e-37	156.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128
TLS3_k127_4506461_6	1317122.ATO12_02585	3.268e-49	180.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HZ83@117743|Flavobacteriia,2YGMK@290174|Aquimarina	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_4506461_7	1296416.JACB01000026_gene4013	8.827e-46	169.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HZ83@117743|Flavobacteriia,2YGMK@290174|Aquimarina	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_4506461_4	1317122.ATO12_02590	1.412e-58	211.0	COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes,1HX8Q@117743|Flavobacteriia,2YHU7@290174|Aquimarina	976|Bacteroidetes	V	ABC-2 type transporter	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
TLS3_k127_4528808_10	714943.Mucpa_6801	2.715e-43	160.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,1IRGP@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_4528808_4	714943.Mucpa_6800	5.462e-91	310.0	COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,1ISE9@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
TLS3_k127_4528808_7	485918.Cpin_1868	3.456e-59	214.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1ISZA@117747|Sphingobacteriia	976|Bacteroidetes	G	Polysaccharide deacetylase	pgdA	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	DUF3298,Polysacc_deac_1
TLS3_k127_4528808_9	153721.MYP_4268	1.98e-48	180.0	COG2834@1|root,COG2834@2|Bacteria,4NT30@976|Bacteroidetes,47RSE@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
TLS3_k127_4528808_13	1121899.Q764_05650	1.226e-13	79.0	29ETG@1|root,301R8@2|Bacteria,4NS07@976|Bacteroidetes,1IID1@117743|Flavobacteriia,2NUQA@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4528808_12	746697.Aeqsu_0915	5.805e-20	94.0	COG0764@1|root,COG0764@2|Bacteria,4NSGQ@976|Bacteroidetes,1I431@117743|Flavobacteriia	976|Bacteroidetes	I	dehydratase	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
TLS3_k127_4528808_8	1122605.KB893648_gene3578	1.547e-52	192.0	COG1434@1|root,COG1434@2|Bacteria,4NNUT@976|Bacteroidetes	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
TLS3_k127_4528808_11	36874.HQ34_00545	1.409e-35	141.0	COG3637@1|root,COG3637@2|Bacteria,4NV08@976|Bacteroidetes,2FYJ1@200643|Bacteroidia,230YU@171551|Porphyromonadaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_4528808_5	485914.Hmuk_2513	3.876e-90	302.0	COG0580@1|root,arCOG04431@2157|Archaea,2XT1N@28890|Euryarchaeota,23YGU@183963|Halobacteria	183963|Halobacteria	G	Major intrinsic protein	-	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
TLS3_k127_4528808_0	1267211.KI669560_gene1159	1.488e-229	719.0	COG0554@1|root,COG0554@2|Bacteria,4NFUH@976|Bacteroidetes,1IP31@117747|Sphingobacteriia	976|Bacteroidetes	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
TLS3_k127_4528808_1	714943.Mucpa_3749	1.504e-178	573.0	COG0578@1|root,COG0578@2|Bacteria,4NEYG@976|Bacteroidetes,1INV4@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM FAD dependent oxidoreductase	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
TLS3_k127_4528808_6	313603.FB2170_05130	2.638e-73	261.0	COG2706@1|root,COG2706@2|Bacteria,4NE87@976|Bacteroidetes,1I0Q4@117743|Flavobacteriia,2PGWD@252356|Maribacter	976|Bacteroidetes	G	Lactonase, 7-bladed beta-propeller	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
TLS3_k127_4528808_3	1168034.FH5T_07485	3.623e-103	346.0	COG3622@1|root,COG3622@2|Bacteria,4NG74@976|Bacteroidetes	976|Bacteroidetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
TLS3_k127_4528808_2	869213.JCM21142_72659	3.714e-159	513.0	COG0673@1|root,COG0673@2|Bacteria,4NF9M@976|Bacteroidetes,47JCP@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
TLS3_k127_4541726_1	760192.Halhy_1519	1.58e-203	645.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IVZC@117747|Sphingobacteriia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
TLS3_k127_4541726_2	866536.Belba_0463	2.809e-42	162.0	2BTVE@1|root,32P38@2|Bacteria,4NRR1@976|Bacteroidetes,47PZ2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4541726_0	760192.Halhy_1519	6.027e-234	747.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IVZC@117747|Sphingobacteriia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
TLS3_k127_4542582_3	1499967.BAYZ01000041_gene2356	4.957e-17	86.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
TLS3_k127_4542582_0	641524.ADICYQ_0478	3.585e-185	587.0	COG0412@1|root,COG0412@2|Bacteria,4NIXW@976|Bacteroidetes,47NY6@768503|Cytophagia	976|Bacteroidetes	Q	COG COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_7,Peptidase_S9
TLS3_k127_4542582_4	234267.Acid_6615	1.68e-12	78.0	28KX8@1|root,2ZAD8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4542582_1	1408473.JHXO01000007_gene811	5.877e-49	179.0	295NE@1|root,2ZSZT@2|Bacteria,4NPQK@976|Bacteroidetes,2FSXA@200643|Bacteroidia	976|Bacteroidetes	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
TLS3_k127_4542582_2	1408473.JHXO01000007_gene810	1.052e-26	112.0	COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,2FQ86@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_4548152_5	869213.JCM21142_52141	2.997e-07	55.0	COG0793@1|root,COG0793@2|Bacteria,4NFKJ@976|Bacteroidetes,47MG1@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	PDZ,PDZ_2,Peptidase_S41
TLS3_k127_4548152_1	927658.AJUM01000017_gene3099	2.046e-142	458.0	COG0330@1|root,COG0330@2|Bacteria,4NH8V@976|Bacteroidetes,2FQPC@200643|Bacteroidia,3XJMP@558415|Marinilabiliaceae	976|Bacteroidetes	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TLS3_k127_4548152_2	385682.AFSL01000072_gene1300	6.668e-138	444.0	COG0330@1|root,COG0330@2|Bacteria,4NHUE@976|Bacteroidetes,2G24T@200643|Bacteroidia,3XJT5@558415|Marinilabiliaceae	976|Bacteroidetes	O	prohibitin homologues	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
TLS3_k127_4548152_3	929713.NIASO_10790	8.588e-120	400.0	COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,1IRJE@117747|Sphingobacteriia	976|Bacteroidetes	MU	TIGRFAM efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family	oprM_4	-	-	ko:K18139,ko:K18300	ko01501,ko02024,map01501,map02024	M00641,M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
TLS3_k127_4548152_0	1123248.KB893314_gene3484	0.0	1304.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IRQ2@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mexF	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
TLS3_k127_4548152_4	1123248.KB893314_gene3485	9.21e-112	372.0	COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,1IR6Z@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mtrC	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS3_k127_4590890_2	1121904.ARBP01000005_gene4474	1.227e-64	234.0	28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4590890_1	525373.HMPREF0766_14072	1.9e-78	274.0	COG0639@1|root,COG0639@2|Bacteria,4NME8@976|Bacteroidetes,1IS77@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
TLS3_k127_4590890_3	761193.Runsl_0274	1.502e-58	216.0	28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4590890_0	927658.AJUM01000047_gene3026	1.299e-237	741.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,2FMIC@200643|Bacteroidia,3XKGZ@558415|Marinilabiliaceae	976|Bacteroidetes	F	Glutamine amidotransferase domain	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
TLS3_k127_4591238_5	1322246.BN4_11465	0.0002916	46.0	COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43EUS@68525|delta/epsilon subdivisions,2X1VB@28221|Deltaproteobacteria,2MA0M@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
TLS3_k127_4591238_4	1121481.AUAS01000015_gene2288	0.0002045	45.0	COG3546@1|root,COG3546@2|Bacteria,4NHRJ@976|Bacteroidetes,47KZB@768503|Cytophagia	976|Bacteroidetes	P	Manganese containing catalase	-	-	-	ko:K07217	-	-	-	-	ko00000	-	-	-	Mn_catalase
TLS3_k127_4591238_2	247490.KSU1_C0449	1.741e-74	271.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
TLS3_k127_4591238_3	945713.IALB_1295	1.595e-11	77.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
TLS3_k127_4591238_0	869213.JCM21142_41666	1.608e-293	922.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,47K7I@768503|Cytophagia	976|Bacteroidetes	P	Outer membrane receptor for ferrienterochelin and colicins	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_4591238_1	761193.Runsl_2121	4.336e-79	288.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,47JEF@768503|Cytophagia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
TLS3_k127_4592058_0	1408473.JHXO01000008_gene2826	2.304e-129	417.0	COG0500@1|root,COG2226@2|Bacteria,4NH9S@976|Bacteroidetes,2FNVG@200643|Bacteroidia	976|Bacteroidetes	Q	Methyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
TLS3_k127_4592058_1	1121129.KB903360_gene3436	1.118e-88	305.0	COG1672@1|root,COG1672@2|Bacteria,4NJHR@976|Bacteroidetes,2G2GK@200643|Bacteroidia,231IS@171551|Porphyromonadaceae	976|Bacteroidetes	S	ATPase domain predominantly from Archaea	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_2
TLS3_k127_4592528_3	926556.Echvi_0789	3.193e-07	56.0	COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,4PKAS@976|Bacteroidetes,47Y5U@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_4592528_1	1408473.JHXO01000001_gene2018	2.546e-50	188.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,2FPGE@200643|Bacteroidia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
TLS3_k127_4592528_0	385682.AFSL01000096_gene608	1.793e-220	694.0	COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,2G0EN@200643|Bacteroidia,3XIYZ@558415|Marinilabiliaceae	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
TLS3_k127_4592528_2	927658.AJUM01000037_gene1904	1.669e-14	73.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,2FSWC@200643|Bacteroidia,3XJ2C@558415|Marinilabiliaceae	976|Bacteroidetes	F	Deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
TLS3_k127_4601610_5	927658.AJUM01000034_gene127	1.408e-87	295.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,2FQNC@200643|Bacteroidia,3XJTF@558415|Marinilabiliaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TLS3_k127_4601610_8	1453500.AT05_06570	1.521e-16	91.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1HZRC@117743|Flavobacteriia	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_4601610_1	1408473.JHXO01000011_gene3028	9.699e-244	792.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,2FMIV@200643|Bacteroidia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
TLS3_k127_4601610_2	1168034.FH5T_05685	4.639e-130	425.0	COG2067@1|root,COG2067@2|Bacteria,4NDZW@976|Bacteroidetes,2FPVJ@200643|Bacteroidia	976|Bacteroidetes	I	Psort location OuterMembrane, score	porV	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4601610_6	933262.AXAM01000018_gene998	2.004e-58	206.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2WJ67@28221|Deltaproteobacteria,2MJZP@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
TLS3_k127_4601610_7	1121898.Q766_08565	4.511e-32	129.0	COG1832@1|root,COG1832@2|Bacteria,4NSE8@976|Bacteroidetes,1I2XU@117743|Flavobacteriia,2NWBD@237|Flavobacterium	976|Bacteroidetes	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
TLS3_k127_4601610_0	1501391.LG35_02070	0.0	1005.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,2FNQK@200643|Bacteroidia,22V6X@171550|Rikenellaceae	976|Bacteroidetes	H	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
TLS3_k127_4601610_4	385682.AFSL01000002_gene1870	4.723e-89	301.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,2FPGP@200643|Bacteroidia,3XIQ9@558415|Marinilabiliaceae	976|Bacteroidetes	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
TLS3_k127_4601610_3	1408473.JHXO01000011_gene3038	4.647e-106	352.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,2FMW2@200643|Bacteroidia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
TLS3_k127_4613962_0	385682.AFSL01000043_gene321	9.194e-106	359.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,2G2X9@200643|Bacteroidia,3XJH3@558415|Marinilabiliaceae	976|Bacteroidetes	CO	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
TLS3_k127_4613962_1	1408473.JHXO01000007_gene981	3.106e-81	283.0	COG1120@1|root,COG1120@2|Bacteria,4NG1Q@976|Bacteroidetes,2FMCI@200643|Bacteroidia	976|Bacteroidetes	HP	ABC transporter, ATP-binding protein	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
TLS3_k127_4613962_2	471854.Dfer_3337	5.438e-24	102.0	COG0609@1|root,COG0609@2|Bacteria,4NEDU@976|Bacteroidetes,47KF2@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
TLS3_k127_4629804_2	694427.Palpr_0989	4.47e-115	375.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,2FNS0@200643|Bacteroidia,22WUR@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
TLS3_k127_4629804_4	525373.HMPREF0766_13787	8.258e-105	349.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,1IPT6@117747|Sphingobacteriia	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
TLS3_k127_4629804_7	869213.JCM21142_73060	1.453e-73	259.0	COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,4NEER@976|Bacteroidetes,47WJ6@768503|Cytophagia	976|Bacteroidetes	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	lytG	-	3.2.1.96	ko:K01227	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,LysM
TLS3_k127_4629804_9	880071.Fleli_1557	6.023e-38	147.0	COG0295@1|root,COG0295@2|Bacteria,4NQED@976|Bacteroidetes,47QAQ@768503|Cytophagia	976|Bacteroidetes	F	cytidine and deoxycytidylate deaminase	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
TLS3_k127_4629804_5	1168034.FH5T_06190	6.038e-93	312.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FSBP@200643|Bacteroidia	976|Bacteroidetes	K	Transcriptional regulatory protein, C terminal	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_4629804_3	1168034.FH5T_06195	1.702e-106	365.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,2FSEE@200643|Bacteroidia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_4629804_6	484018.BACPLE_02391	1.264e-86	292.0	COG0564@1|root,COG0564@2|Bacteria,4NFS8@976|Bacteroidetes,2FN9G@200643|Bacteroidia,4AKPN@815|Bacteroidaceae	976|Bacteroidetes	J	ribosomal pseudouridine synthase C, large subunit	rluC	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
TLS3_k127_4629804_1	709991.Odosp_0507	1.055e-132	427.0	COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,2FNNC@200643|Bacteroidia,22WEU@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
TLS3_k127_4629804_0	411477.PARMER_00774	0.0	1036.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,22VY9@171551|Porphyromonadaceae	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
TLS3_k127_4629804_8	869213.JCM21142_41700	1.113e-48	184.0	COG2849@1|root,COG2849@2|Bacteria,4NP2Z@976|Bacteroidetes	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_4629804_10	1379698.RBG1_1C00001G1263	1.665e-06	54.0	COG1404@1|root,COG1404@2|Bacteria,2NNSK@2323|unclassified Bacteria	2|Bacteria	O	Subtilase family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_4644849_2	1408473.JHXO01000012_gene336	5.967e-55	194.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	-	-	-	ko:K06950,ko:K09163	-	-	-	-	ko00000	-	-	-	HD
TLS3_k127_4644849_0	1408473.JHXO01000012_gene337	4.279e-191	603.0	COG0473@1|root,COG0473@2|Bacteria,4NGUA@976|Bacteroidetes	976|Bacteroidetes	CE	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.41,1.1.1.42,1.1.1.85	ko:K00030,ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00432,M00535,M00740	R00267,R00268,R00709,R00994,R01899,R04426,R10052	RC00001,RC00084,RC00114,RC00417,RC00626,RC02801,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
TLS3_k127_4644849_1	1408473.JHXO01000007_gene718	8.156e-158	511.0	COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,2FNVV@200643|Bacteroidia	976|Bacteroidetes	E	Xaa-His dipeptidase	pepD_1	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_4644849_4	868131.MSWAN_2151	1.017e-22	97.0	COG0369@1|root,COG1773@1|root,arCOG02430@2157|Archaea,arCOG04391@2157|Archaea,2XV44@28890|Euryarchaeota,23NS7@183925|Methanobacteria	183925|Methanobacteria	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane,Rubredoxin
TLS3_k127_4644849_3	1408473.JHXO01000012_gene338	1.6e-24	103.0	COG3051@1|root,COG3051@2|Bacteria,4NJUR@976|Bacteroidetes,2FRJJ@200643|Bacteroidia	976|Bacteroidetes	C	Citrate lyase, alpha subunit (CitF)	citF	-	-	-	-	-	-	-	-	-	-	-	CitF
TLS3_k127_4647909_2	1356852.N008_06865	2.813e-27	117.0	28I8D@1|root,2Z8B7@2|Bacteria,4NM23@976|Bacteroidetes,47NIB@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
TLS3_k127_4647909_1	1121957.ATVL01000010_gene370	4.672e-63	241.0	COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,47M8I@768503|Cytophagia	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4647909_0	1122605.KB893647_gene368	3.942e-170	546.0	COG0673@1|root,COG0673@2|Bacteria,4P16C@976|Bacteroidetes,1IWQM@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_4652971_2	1408473.JHXO01000010_gene3531	9.217e-65	229.0	COG2846@1|root,COG2846@2|Bacteria,4NMCR@976|Bacteroidetes,2FMRX@200643|Bacteroidia	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin
TLS3_k127_4652971_3	1408473.JHXO01000010_gene3530	2.438e-44	168.0	COG2197@1|root,COG2197@2|Bacteria,4NNVV@976|Bacteroidetes,2FN9B@200643|Bacteroidia	976|Bacteroidetes	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE
TLS3_k127_4652971_0	694427.Palpr_1466	2.948e-87	301.0	COG3659@1|root,COG3659@2|Bacteria,4PBVM@976|Bacteroidetes,2G1SN@200643|Bacteroidia,2317X@171551|Porphyromonadaceae	976|Bacteroidetes	M	Carbohydrate-selective porin, OprB family	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
TLS3_k127_4652971_1	694427.Palpr_1465	1.44e-81	275.0	COG0370@1|root,COG1918@1|root,COG0370@2|Bacteria,COG1918@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia,22VWF@171551|Porphyromonadaceae	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
TLS3_k127_4655615_1	927658.AJUM01000037_gene2124	1.976e-171	551.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,2FMIK@200643|Bacteroidia,3XIWX@558415|Marinilabiliaceae	976|Bacteroidetes	L	DNA mismatch repair protein, C-terminal domain	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
TLS3_k127_4655615_0	1408473.JHXO01000008_gene2836	1.228e-196	622.0	COG4403@1|root,COG4403@2|Bacteria,4PMC1@976|Bacteroidetes	976|Bacteroidetes	V	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS3_k127_4655615_2	1408473.JHXO01000008_gene2837	1.09e-31	126.0	COG0348@1|root,COG1622@1|root,COG0348@2|Bacteria,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	vnfA	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,Fer4_5,Sigma54_activat,cNMP_binding
TLS3_k127_4657679_1	1408473.JHXO01000006_gene1395	3.272e-47	172.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4657679_0	1408473.JHXO01000006_gene1394	2.968e-84	291.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,2FMP7@200643|Bacteroidia	976|Bacteroidetes	M	heptosyltransferase	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
TLS3_k127_4657679_2	946077.W5A_04089	1.136e-34	135.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
TLS3_k127_4671127_4	1150600.ADIARSV_1372	1.246e-41	158.0	COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,1ITC4@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
TLS3_k127_4671127_0	927658.AJUM01000037_gene2249	0.0	1170.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,2FPAU@200643|Bacteroidia,3XJ07@558415|Marinilabiliaceae	976|Bacteroidetes	L	DNA Topoisomerase IV	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
TLS3_k127_4671127_1	709991.Odosp_1064	1.784e-299	928.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,2FMMD@200643|Bacteroidia,22VXW@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA topoisomerase (ATP-hydrolyzing)	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
TLS3_k127_4671127_2	1408473.JHXO01000011_gene2993	1.031e-118	404.0	COG0249@1|root,COG0249@2|Bacteria,4NE6X@976|Bacteroidetes,2FM62@200643|Bacteroidia	976|Bacteroidetes	L	MutS domain V protein	mutS_2	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
TLS3_k127_4671127_5	395494.Galf_0048	3.855e-19	97.0	2D5F0@1|root,32TIY@2|Bacteria,1N1FC@1224|Proteobacteria,2VYG3@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4671127_3	96561.Dole_2499	6.102e-44	169.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42QIX@68525|delta/epsilon subdivisions,2WJHE@28221|Deltaproteobacteria,2MIMI@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TLS3_k127_4674719_1	1313172.YM304_16440	9.598e-06	49.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CMSW@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
TLS3_k127_4674719_0	1123276.KB893245_gene1774	0.0	1335.0	COG3408@1|root,COG3408@2|Bacteria,4NESP@976|Bacteroidetes,47P6A@768503|Cytophagia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
TLS3_k127_4682850_0	1408473.JHXO01000001_gene1964	4.258e-88	302.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,2FNHB@200643|Bacteroidia	976|Bacteroidetes	M	Efflux ABC transporter, permease protein	lolE	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
TLS3_k127_4682850_2	1408473.JHXO01000001_gene2167	1.293e-79	280.0	COG0402@1|root,COG0402@2|Bacteria,4NJVU@976|Bacteroidetes	976|Bacteroidetes	F	amidohydrolase	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
TLS3_k127_4682850_1	1168034.FH5T_09365	1.506e-87	295.0	COG0731@1|root,COG0731@2|Bacteria,4NJEM@976|Bacteroidetes,2FMWY@200643|Bacteroidia	976|Bacteroidetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
TLS3_k127_469144_0	1168034.FH5T_10710	5.652e-100	341.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,2FM98@200643|Bacteroidia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
TLS3_k127_469144_2	385682.AFSL01000079_gene1042	2.256e-08	58.0	2AD0X@1|root,312NX@2|Bacteria,4PHN1@976|Bacteroidetes,2G28C@200643|Bacteroidia,3XKBM@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_469144_1	1408433.JHXV01000009_gene1313	1.563e-21	99.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,1IMRK@117743|Flavobacteriia,2PBRK@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
TLS3_k127_4728732_1	909663.KI867150_gene372	3.697e-168	537.0	COG0444@1|root,COG0444@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
TLS3_k127_4728732_0	1408473.JHXO01000012_gene373	7.243e-321	1002.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,2FX71@200643|Bacteroidia	976|Bacteroidetes	C	Dehydrogenase E1 component	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
TLS3_k127_4728732_2	869213.JCM21142_2	1.505e-10	65.0	2EIGM@1|root,33C80@2|Bacteria,4NXRF@976|Bacteroidetes	976|Bacteroidetes	S	COG NOG35566 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4756055_1	1168034.FH5T_07945	4.864e-125	410.0	COG0477@1|root,COG2814@2|Bacteria,4NHVY@976|Bacteroidetes,2FP43@200643|Bacteroidia	976|Bacteroidetes	EGP	Transporter, major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_4756055_0	1168034.FH5T_07950	7.28e-190	615.0	COG4772@1|root,COG4772@2|Bacteria,4NF0U@976|Bacteroidetes,2FM7N@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
TLS3_k127_4762227_0	357276.EL88_00685	4.628e-181	574.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,2FNNY@200643|Bacteroidia,4ANAU@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
TLS3_k127_4762227_1	1121904.ARBP01000001_gene5968	2.004e-104	344.0	COG0800@1|root,COG0800@2|Bacteria,4NEFY@976|Bacteroidetes,47PM4@768503|Cytophagia	976|Bacteroidetes	G	PFAM KDPG and KHG aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
TLS3_k127_4762227_2	999419.HMPREF1077_00426	1.415e-48	184.0	2DBYM@1|root,2ZBW8@2|Bacteria,4NHDU@976|Bacteroidetes,2FQXP@200643|Bacteroidia,22Y34@171551|Porphyromonadaceae	976|Bacteroidetes	S	6-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128
TLS3_k127_4765795_1	880070.Cycma_3864	9.633e-102	353.0	COG0457@1|root,COG2114@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,47N72@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_19,TPR_8
TLS3_k127_4765795_4	251229.Chro_3389	1.407e-38	153.0	2CYFR@1|root,32T44@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
TLS3_k127_4765795_0	1499967.BAYZ01000100_gene3468	1.407e-105	347.0	COG0655@1|root,COG0655@2|Bacteria	2|Bacteria	S	NAD(P)H dehydrogenase (quinone) activity	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
TLS3_k127_4765795_5	588581.Cpap_2280	0.0001475	44.0	COG1233@1|root,COG1233@2|Bacteria,1TS4A@1239|Firmicutes,249K1@186801|Clostridia,3WHBS@541000|Ruminococcaceae	186801|Clostridia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
TLS3_k127_4765795_3	498761.HM1_2853	5.661e-42	160.0	COG1595@1|root,COG1595@2|Bacteria,1V3G9@1239|Firmicutes,24G1Y@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	sigZ	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_4765795_2	1265505.ATUG01000002_gene1702	3.205e-75	263.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42UHV@68525|delta/epsilon subdivisions,2WQCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
TLS3_k127_4768208_2	927658.AJUM01000042_gene1725	3.488e-12	68.0	2DRDY@1|root,33BC0@2|Bacteria,4NXM8@976|Bacteroidetes,2G29C@200643|Bacteroidia,3XKFD@558415|Marinilabiliaceae	976|Bacteroidetes	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
TLS3_k127_4768208_0	927658.AJUM01000034_gene299	4.534e-261	824.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,2FMM6@200643|Bacteroidia,3XIQP@558415|Marinilabiliaceae	976|Bacteroidetes	K	RNB	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
TLS3_k127_4768208_1	1235803.C825_01663	1.911e-43	169.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,2FM97@200643|Bacteroidia,22WAH@171551|Porphyromonadaceae	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
TLS3_k127_4774821_2	1123008.KB905693_gene1324	1.203e-75	259.0	COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,2FPPX@200643|Bacteroidia,22W4P@171551|Porphyromonadaceae	976|Bacteroidetes	Q	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase	fahA	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
TLS3_k127_4774821_1	1123008.KB905701_gene2243	3.995e-112	366.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,2FMQF@200643|Bacteroidia,22WYR@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA polymerase III subunit epsilon	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
TLS3_k127_4774821_0	1408473.JHXO01000011_gene3064	3.348e-169	538.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,2FMPF@200643|Bacteroidia	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
TLS3_k127_477962_1	468059.AUHA01000002_gene1162	7.385e-34	132.0	COG1541@1|root,COG1541@2|Bacteria	2|Bacteria	H	phenylacetate-CoA ligase activity	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
TLS3_k127_477962_0	468059.AUHA01000002_gene1161	1.935e-204	644.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,4NFEW@976|Bacteroidetes	976|Bacteroidetes	E	Oxidoreductase NAD-binding domain protein	-	-	-	ko:K02030,ko:K03810	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	ADH_zinc_N,GFO_IDH_MocA
TLS3_k127_4791884_5	1239962.C943_00093	2.64e-08	65.0	COG0659@1|root,COG0659@2|Bacteria,4NFX2@976|Bacteroidetes,47KT5@768503|Cytophagia	976|Bacteroidetes	U	Sulfate permease family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
TLS3_k127_4791884_3	667014.Thein_0389	4.042e-47	181.0	COG0288@1|root,COG0288@2|Bacteria,2GI61@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
TLS3_k127_4791884_0	468059.AUHA01000002_gene1259	8.268e-228	726.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1IPID@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
TLS3_k127_4791884_4	1392490.JHZX01000001_gene3527	1.171e-12	81.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFBK@976|Bacteroidetes,1HY8A@117743|Flavobacteriia	976|Bacteroidetes	EU	peptidase S9	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
TLS3_k127_4791884_2	1279009.ADICEAN_01645	1.165e-63	232.0	COG1317@1|root,COG1317@2|Bacteria,4PPFZ@976|Bacteroidetes,47YMJ@768503|Cytophagia	976|Bacteroidetes	NU	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
TLS3_k127_4791884_1	742766.HMPREF9455_02525	7.159e-187	595.0	COG0673@1|root,COG0673@2|Bacteria,4NH13@976|Bacteroidetes,2FPIH@200643|Bacteroidia,22WA6@171551|Porphyromonadaceae	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_4800060_0	869213.JCM21142_31199	9.344e-62	217.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,4NHXQ@976|Bacteroidetes,47JFU@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
TLS3_k127_4800060_2	1122176.KB903546_gene1007	1.553e-26	118.0	2CJVV@1|root,32SAW@2|Bacteria,4NTMY@976|Bacteroidetes,1J17A@117747|Sphingobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_4800060_1	1408473.JHXO01000006_gene1089	4.958e-49	184.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,2FMM9@200643|Bacteroidia	976|Bacteroidetes	O	Psort location Cytoplasmic, score 8.96	gldB	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4802732_3	385682.AFSL01000008_gene2530	4.432e-81	273.0	COG0129@1|root,COG0129@2|Bacteria,4NFHP@976|Bacteroidetes,2FMCC@200643|Bacteroidia,3XJDZ@558415|Marinilabiliaceae	976|Bacteroidetes	EG	Dehydratase family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
TLS3_k127_4802732_1	1237149.C900_01875	1.112e-222	704.0	COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,47KS8@768503|Cytophagia	976|Bacteroidetes	EH	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TLS3_k127_4802732_5	886379.AEWI01000023_gene40	1.628e-57	206.0	COG0440@1|root,COG0440@2|Bacteria,4NIDK@976|Bacteroidetes,2FNQ4@200643|Bacteroidia,3XJIE@558415|Marinilabiliaceae	976|Bacteroidetes	E	ACT domain	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
TLS3_k127_4802732_2	452637.Oter_3478	2.701e-170	541.0	COG0059@1|root,COG0059@2|Bacteria,46SI2@74201|Verrucomicrobia,3K7PK@414999|Opitutae	74201|Verrucomicrobia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
TLS3_k127_4802732_0	886379.AEWI01000023_gene38	7.665e-249	775.0	COG0119@1|root,COG0119@2|Bacteria,4NEIT@976|Bacteroidetes,2FNX8@200643|Bacteroidia,3XIXN@558415|Marinilabiliaceae	976|Bacteroidetes	E	LeuA allosteric (dimerisation) domain	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
TLS3_k127_4802732_4	1121931.AUHG01000011_gene2270	3.535e-60	210.0	COG0065@1|root,COG0065@2|Bacteria,4NG7E@976|Bacteroidetes,1HWPT@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
TLS3_k127_4803063_1	269797.Mbar_A2478	9.758e-69	243.0	COG1073@1|root,arCOG01661@2157|Archaea,2XVIC@28890|Euryarchaeota,2NANZ@224756|Methanomicrobia	224756|Methanomicrobia	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Peptidase_S9
TLS3_k127_4803063_2	1450525.JATV01000014_gene2229	7.111e-49	177.0	COG3682@1|root,COG3682@2|Bacteria,4NP4S@976|Bacteroidetes,1I229@117743|Flavobacteriia,2NWBX@237|Flavobacterium	976|Bacteroidetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
TLS3_k127_4803063_4	693979.Bache_3008	3.736e-37	161.0	COG4219@1|root,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,2FNCU@200643|Bacteroidia,4ANSE@815|Bacteroidaceae	976|Bacteroidetes	KT	COG NOG25147 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
TLS3_k127_4803063_0	1168034.FH5T_18655	4.096e-70	253.0	COG0438@1|root,COG0438@2|Bacteria,4NW2W@976|Bacteroidetes,2FR6M@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
TLS3_k127_4803063_3	96561.Dole_1797	1.261e-46	181.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,42T4H@68525|delta/epsilon subdivisions,2WPIT@28221|Deltaproteobacteria,2MM2A@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
TLS3_k127_4803063_5	1121286.AUMT01000004_gene1022	2.295e-16	87.0	COG0189@1|root,COG0189@2|Bacteria,4NHYZ@976|Bacteroidetes,1IN97@117743|Flavobacteriia,3ZTVA@59732|Chryseobacterium	976|Bacteroidetes	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	RimK
TLS3_k127_4811406_1	667015.Bacsa_1861	2.644e-188	599.0	COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,2FM6I@200643|Bacteroidia,4ANQ3@815|Bacteroidaceae	976|Bacteroidetes	J	Psort location Cytoplasmic, score	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
TLS3_k127_4811406_0	929704.Myrod_0357	2.464e-199	632.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1HX2V@117743|Flavobacteriia,47HA8@76831|Myroides	976|Bacteroidetes	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
TLS3_k127_4822479_0	1168289.AJKI01000065_gene3766	2.712e-158	511.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FMRV@200643|Bacteroidia,3XKRU@558415|Marinilabiliaceae	976|Bacteroidetes	T	Magnesium chelatase, subunit ChlI	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_4822479_2	1408473.JHXO01000001_gene2024	2.78e-96	321.0	COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,2FMDA@200643|Bacteroidia	976|Bacteroidetes	V	bacteriocin export ABC transporter, lactococcin 972 group	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_4822479_1	927658.AJUM01000011_gene1330	1.571e-116	404.0	COG0577@1|root,COG0577@2|Bacteria,4NFGD@976|Bacteroidetes,2FNP6@200643|Bacteroidia	976|Bacteroidetes	V	ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_4822479_3	1121931.AUHG01000010_gene506	2.073e-59	212.0	COG1670@1|root,COG1670@2|Bacteria,4NNBE@976|Bacteroidetes,1I22F@117743|Flavobacteriia	976|Bacteroidetes	J	Polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_4822479_4	926569.ANT_03690	1.647e-26	112.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	3.4.11.10,3.4.11.24,3.4.11.6	ko:K19701,ko:K19702	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
TLS3_k127_4822535_0	1121920.AUAU01000013_gene1721	1.137e-89	304.0	COG0667@1|root,COG0667@2|Bacteria,3Y3TE@57723|Acidobacteria	57723|Acidobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_4822535_1	720554.Clocl_3211	8.294e-34	137.0	COG0188@1|root,COG0188@2|Bacteria,1TPPU@1239|Firmicutes,24CU3@186801|Clostridia,3WG8X@541000|Ruminococcaceae	186801|Clostridia	L	PFAM DNA gyrase topoisomerase IV, subunit A	-	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
TLS3_k127_4822535_3	1123242.JH636435_gene2937	7.002e-28	122.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
TLS3_k127_4822535_2	694427.Palpr_0022	5.761e-33	130.0	COG0526@1|root,COG0526@2|Bacteria,4PKQI@976|Bacteroidetes,2G0RN@200643|Bacteroidia,22YJJ@171551|Porphyromonadaceae	976|Bacteroidetes	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
TLS3_k127_4822535_4	1313421.JHBV01000003_gene677	1.915e-07	60.0	COG4938@1|root,COG4938@2|Bacteria,4NMVA@976|Bacteroidetes	976|Bacteroidetes	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,DUF3696
TLS3_k127_485370_1	468059.AUHA01000006_gene3015	4.204e-158	503.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1IQJT@117747|Sphingobacteriia	976|Bacteroidetes	V	Mate efflux family protein	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
TLS3_k127_485370_0	290315.Clim_0886	1.085e-176	563.0	COG1883@1|root,COG1883@2|Bacteria,1FEQK@1090|Chlorobi	1090|Chlorobi	C	PFAM Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
TLS3_k127_485370_3	517418.Ctha_0176	3.533e-39	150.0	COG4770@1|root,COG4770@2|Bacteria,1FF63@1090|Chlorobi	1090|Chlorobi	I	PFAM biotin lipoyl attachment domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
TLS3_k127_485370_4	1121904.ARBP01000026_gene672	4.201e-18	88.0	COG3630@1|root,COG3630@2|Bacteria,4NV8J@976|Bacteroidetes	976|Bacteroidetes	C	COG NOG19100 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	LTD,OAD_gamma
TLS3_k127_485370_2	1168034.FH5T_18420	1.883e-87	290.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,2FM4G@200643|Bacteroidia	976|Bacteroidetes	I	Carboxyl transferase domain protein	mmdA	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
TLS3_k127_4872192_1	471854.Dfer_0514	4.903e-71	249.0	COG4242@1|root,COG4242@2|Bacteria,4NI55@976|Bacteroidetes,47PDB@768503|Cytophagia	976|Bacteroidetes	PQ	Peptidase family S51	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
TLS3_k127_4872192_0	1185876.BN8_00961	3.905e-309	970.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,4NEDY@976|Bacteroidetes,47MQF@768503|Cytophagia	976|Bacteroidetes	HJM	Belongs to the MurCDEF family	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,RimK
TLS3_k127_4902929_3	431947.PGN_1678	2.747e-07	55.0	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,2FTSK@200643|Bacteroidia,22YD9@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
TLS3_k127_4902929_1	1416760.AYMS01000012_gene963	1.488e-49	182.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,1HX1J@117743|Flavobacteriia,47HUN@76831|Myroides	976|Bacteroidetes	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
TLS3_k127_4902929_0	1121931.AUHG01000015_gene1249	9.633e-103	338.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1HXPP@117743|Flavobacteriia	976|Bacteroidetes	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_4902929_2	927658.AJUM01000022_gene992	9.484e-39	151.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,2FNB5@200643|Bacteroidia,3XJW0@558415|Marinilabiliaceae	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
TLS3_k127_4945085_3	925409.KI911562_gene1798	1.066e-14	76.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin,Thioredoxin_8
TLS3_k127_4945085_2	1168289.AJKI01000031_gene1001	1.02e-54	203.0	COG0679@1|root,COG0679@2|Bacteria,4NX5F@976|Bacteroidetes,2FQNK@200643|Bacteroidia,3XKQC@558415|Marinilabiliaceae	976|Bacteroidetes	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
TLS3_k127_4945085_0	1535422.ND16A_2603	3.083e-311	964.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,2Q5Y6@267889|Colwelliaceae	1224|Proteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
TLS3_k127_4945085_1	243233.MCA1772	1.551e-133	443.0	COG2244@1|root,COG2244@2|Bacteria,1R512@1224|Proteobacteria,1RZ0F@1236|Gammaproteobacteria,1XE8D@135618|Methylococcales	135618|Methylococcales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
TLS3_k127_4945281_0	1121859.KB890750_gene225	1.511e-149	484.0	28HII@1|root,2Z7TZ@2|Bacteria,4NHR6@976|Bacteroidetes,47MJR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4945281_1	1121904.ARBP01000010_gene2291	2.204e-37	145.0	COG1082@1|root,COG1082@2|Bacteria,4NIG9@976|Bacteroidetes,47NIT@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_4950241_0	760192.Halhy_4949	1.121e-285	895.0	COG3408@1|root,COG3408@2|Bacteria,4NESP@976|Bacteroidetes,1INWR@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Bacterial alpha-L-rhamnosidase	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
TLS3_k127_4950241_2	385682.AFSL01000072_gene1341	1.95e-143	462.0	COG0697@1|root,2Z7ID@2|Bacteria,4NEHB@976|Bacteroidetes,2FN7F@200643|Bacteroidia	976|Bacteroidetes	EG	L-rhamnose-proton symport protein (RhaT)	rhaT	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
TLS3_k127_4950241_3	1191523.MROS_0076	2.399e-44	162.0	COG3254@1|root,COG3254@2|Bacteria	2|Bacteria	S	rhamnose metabolic process	rhaU	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
TLS3_k127_4950241_1	385682.AFSL01000072_gene1340	1.772e-203	640.0	COG4806@1|root,COG4806@2|Bacteria,4NHKW@976|Bacteroidetes,2FNVS@200643|Bacteroidia	976|Bacteroidetes	G	Psort location Cytoplasmic, score 8.96	rhaA	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008740,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
TLS3_k127_4972759_1	1137281.D778_02774	2.373e-167	541.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia	976|Bacteroidetes	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS3_k127_4972759_2	869213.JCM21142_41954	1.204e-134	436.0	COG0171@1|root,COG0171@2|Bacteria,4NEXG@976|Bacteroidetes	976|Bacteroidetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	-	-	-	-	-	-	-	-	-	-	-	-	NAD_synthase
TLS3_k127_4972759_0	1125863.JAFN01000001_gene613	1.575e-276	858.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WKK3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TLS3_k127_4972759_3	517418.Ctha_2132	4.026e-119	394.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
TLS3_k127_4986322_0	153721.MYP_3734	3.79e-282	878.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,47KWA@768503|Cytophagia	976|Bacteroidetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
TLS3_k127_4986322_1	1408813.AYMG01000008_gene4040	5.047e-23	103.0	COG1225@1|root,COG1225@2|Bacteria,4NKV2@976|Bacteroidetes,1IX9A@117747|Sphingobacteriia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TLS3_k127_4992647_5	1358423.N180_16480	2.135e-51	185.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1IQ8P@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
TLS3_k127_4992647_4	762903.Pedsa_1064	4.041e-161	529.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
TLS3_k127_4992647_2	927658.AJUM01000043_gene792	2.276e-183	594.0	COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,3XIXI@558415|Marinilabiliaceae	976|Bacteroidetes	A	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
TLS3_k127_4992647_0	929556.Solca_2111	4.196e-257	801.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,1IP4J@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
TLS3_k127_4992647_3	1408473.JHXO01000008_gene2784	1.208e-162	533.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,2FN3A@200643|Bacteroidia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
TLS3_k127_4992647_6	649639.Bcell_1339	1.851e-20	103.0	COG1609@1|root,COG1609@2|Bacteria,1TQSY@1239|Firmicutes,4HAJI@91061|Bacilli,1ZEA9@1386|Bacillus	91061|Bacilli	K	transcriptional	regR	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3,Peripla_BP_4
TLS3_k127_4992647_1	999419.HMPREF1077_01783	2.08e-205	669.0	COG1305@1|root,COG1305@2|Bacteria,4NFR8@976|Bacteroidetes,2FPAP@200643|Bacteroidia,22W3W@171551|Porphyromonadaceae	976|Bacteroidetes	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
TLS3_k127_4992647_7	929556.Solca_0617	1.36e-18	90.0	COG4206@1|root,COG4206@2|Bacteria,4NED9@976|Bacteroidetes,1IQW0@117747|Sphingobacteriia	976|Bacteroidetes	H	TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
TLS3_k127_5053920_2	1168034.FH5T_11610	8.422e-114	384.0	COG1538@1|root,COG1538@2|Bacteria,4NGXM@976|Bacteroidetes,2FMD9@200643|Bacteroidia	976|Bacteroidetes	MU	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_5053920_0	1121904.ARBP01000005_gene4602	3.784e-153	496.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,47JWH@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_5053920_3	1124780.ANNU01000021_gene3028	6.255e-104	356.0	COG0845@1|root,COG0845@2|Bacteria,4NGSC@976|Bacteroidetes,47TMZ@768503|Cytophagia	976|Bacteroidetes	M	HlyD membrane-fusion protein of T1SS	-	-	-	-	-	-	-	-	-	-	-	-	HlyD,HlyD_3,HlyD_D23
TLS3_k127_5053920_1	999419.HMPREF1077_03521	1.025e-130	425.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,2FM6E@200643|Bacteroidia,22W7N@171551|Porphyromonadaceae	976|Bacteroidetes	G	Phosphoglucosamine mutase	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TLS3_k127_5075692_2	742725.HMPREF9450_02168	3.359e-78	267.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,2FNUW@200643|Bacteroidia,22V1S@171550|Rikenellaceae	976|Bacteroidetes	E	Dihydrodipicolinate reductase, C-terminus	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
TLS3_k127_5075692_0	742817.HMPREF9449_00747	2.972e-148	482.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,2FNMS@200643|Bacteroidia,22W4M@171551|Porphyromonadaceae	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
TLS3_k127_5075692_4	742817.HMPREF9449_00745	2.934e-48	174.0	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,2FSHF@200643|Bacteroidia,22XVI@171551|Porphyromonadaceae	976|Bacteroidetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
TLS3_k127_5075692_5	411477.PARMER_00482	1.739e-22	98.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,2FUKE@200643|Bacteroidia,22YNZ@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
TLS3_k127_5075692_3	742767.HMPREF9456_02414	9.27e-76	258.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,2FNF1@200643|Bacteroidia,22X5B@171551|Porphyromonadaceae	976|Bacteroidetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
TLS3_k127_5075692_1	1168289.AJKI01000030_gene1157	6.275e-131	421.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,2FMAU@200643|Bacteroidia,3XJJD@558415|Marinilabiliaceae	976|Bacteroidetes	J	Threonyl and Alanyl tRNA synthetase second additional domain	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
TLS3_k127_5091376_2	1267535.KB906767_gene2278	1.278e-78	280.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
TLS3_k127_5091376_1	1168034.FH5T_10045	5.433e-115	381.0	COG0263@1|root,COG0263@2|Bacteria,4NH75@976|Bacteroidetes,2FM31@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
TLS3_k127_5091376_0	1408473.JHXO01000006_gene1230	1.843e-167	535.0	COG0014@1|root,COG0014@2|Bacteria,4NEPQ@976|Bacteroidetes,2FN24@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_5091376_3	1121957.ATVL01000008_gene4558	1.699e-27	112.0	COG0538@1|root,COG0538@2|Bacteria,4PKW6@976|Bacteroidetes,47NMD@768503|Cytophagia	976|Bacteroidetes	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
TLS3_k127_509177_3	1120966.AUBU01000005_gene3555	3.373e-120	391.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,47MN7@768503|Cytophagia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
TLS3_k127_509177_4	385682.AFSL01000003_gene1904	5.864e-78	267.0	COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,2FSD1@200643|Bacteroidia,3XKJU@558415|Marinilabiliaceae	976|Bacteroidetes	H	2-phosphosulpholactate phosphatase	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
TLS3_k127_509177_1	886379.AEWI01000049_gene3211	1.489e-173	550.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,2FMET@200643|Bacteroidia,3XJSG@558415|Marinilabiliaceae	976|Bacteroidetes	EH	Aminotransferase class-V	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
TLS3_k127_509177_2	886379.AEWI01000049_gene3210	9.951e-122	397.0	COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,3XJE4@558415|Marinilabiliaceae	976|Bacteroidetes	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TLS3_k127_509177_0	886379.AEWI01000049_gene3209	5.783e-204	640.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,2FN23@200643|Bacteroidia,3XJ7V@558415|Marinilabiliaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
TLS3_k127_509177_5	1408473.JHXO01000004_gene135	3.652e-76	262.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,2FM94@200643|Bacteroidia	976|Bacteroidetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
TLS3_k127_509177_6	880526.KE386488_gene1826	2.064e-25	109.0	COG0167@1|root,COG0167@2|Bacteria,4NF4D@976|Bacteroidetes,2FM0X@200643|Bacteroidia,22U2V@171550|Rikenellaceae	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate	preA	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
TLS3_k127_5092111_6	861299.J421_4032	7.852e-171	568.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_4032|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5092111_3	1123248.KB893326_gene1334	3.41e-272	843.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1IRBM@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_5092111_17	1144342.PMI40_00827	3.207e-07	62.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VH55@28216|Betaproteobacteria,472XP@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport system, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
TLS3_k127_5092111_11	203119.Cthe_0880	1e-105	349.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,3WG9J@541000|Ruminococcaceae	186801|Clostridia	E	synthase	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
TLS3_k127_5092111_9	335543.Sfum_1620	1.343e-121	403.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
TLS3_k127_5092111_15	234267.Acid_6082	4.989e-49	182.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	rapK	GO:0003674,GO:0003824,GO:0016787,GO:0016801,GO:0016803	3.3.2.13,4.1.3.40,4.1.3.45	ko:K18239,ko:K18240	ko00130,ko00400,ko01100,ko01110,map00130,map00400,map01100,map01110	M00117	R01302,R10583,R10597	RC00350,RC00491,RC02148,RC03212	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribonuc_L-PSP
TLS3_k127_5092111_12	335543.Sfum_1621	2.052e-96	328.0	COG3292@1|root,COG3292@2|Bacteria,1QU1S@1224|Proteobacteria,42WTY@68525|delta/epsilon subdivisions,2WSR0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PKD,Peptidase_C13,Reg_prop
TLS3_k127_5092111_8	335543.Sfum_1622	9.922e-142	473.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1R7E0@1224|Proteobacteria,42XD8@68525|delta/epsilon subdivisions,2WT8U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_C554
TLS3_k127_5092111_16	452637.Oter_2952	2.131e-33	146.0	COG0823@1|root,COG0823@2|Bacteria,46XCP@74201|Verrucomicrobia,3K9X8@414999|Opitutae	414999|Opitutae	U	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5092111_7	335543.Sfum_1623	1.645e-164	535.0	COG3118@1|root,COG3118@2|Bacteria,1PQ8G@1224|Proteobacteria	1224|Proteobacteria	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
TLS3_k127_5092111_10	926562.Oweho_2065	3.964e-112	378.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,4NEIS@976|Bacteroidetes,1HXGB@117743|Flavobacteriia,2PBKD@246874|Cryomorphaceae	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	arlS_1	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_5092111_13	926562.Oweho_2064	8.603e-84	285.0	COG0745@1|root,COG0745@2|Bacteria,4NE77@976|Bacteroidetes,1IMIZ@117743|Flavobacteriia	976|Bacteroidetes	T	transcriptional regulator	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_5092111_1	1048983.EL17_06380	7.547e-318	1004.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47Y6D@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
TLS3_k127_5092111_5	1048983.EL17_06385	6.148e-176	568.0	COG1395@1|root,COG1395@2|Bacteria,4PMSD@976|Bacteroidetes,47Y95@768503|Cytophagia	976|Bacteroidetes	K	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_5092111_2	1123057.P872_16125	3.169e-272	874.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47JJ5@768503|Cytophagia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
TLS3_k127_5092111_0	1235803.C825_02804	1.239e-318	1009.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_5092111_4	1235803.C825_02805	1.708e-185	597.0	COG0446@1|root,COG0446@2|Bacteria,4NE3A@976|Bacteroidetes,2FRH5@200643|Bacteroidia,22WU3@171551|Porphyromonadaceae	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_5092111_14	909663.KI867150_gene375	1.462e-70	251.0	COG1349@1|root,COG1349@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	3.6.4.12	ko:K02444,ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	AlbA_2,DUF1670,DeoRC,HATPase_c_4,HTH_DeoR
TLS3_k127_5092111_18	477974.Daud_0686	0.0001622	48.0	COG1349@1|root,COG1349@2|Bacteria,1VC1B@1239|Firmicutes,24P9E@186801|Clostridia,265X6@186807|Peptococcaceae	186801|Clostridia	GK	Protein of unknown function (DUF1670)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1670
TLS3_k127_5109102_2	761193.Runsl_4865	8.583e-152	488.0	COG2272@1|root,COG2272@2|Bacteria,4NG5B@976|Bacteroidetes,47JGD@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
TLS3_k127_5109102_1	1123277.KB893195_gene5644	5.558e-158	506.0	COG2382@1|root,COG2382@2|Bacteria,4NFVV@976|Bacteroidetes,47M66@768503|Cytophagia	976|Bacteroidetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	CBM_48,Esterase
TLS3_k127_5109102_0	865937.Gilli_2495	0.0	1020.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia,2P5GQ@244698|Gillisia	976|Bacteroidetes	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_5109102_3	1047013.AQSP01000138_gene1017	4.621e-32	128.0	COG0612@1|root,COG0612@2|Bacteria,2NP5H@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_5115241_1	344747.PM8797T_09144	1.23e-20	94.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,2J4TJ@203682|Planctomycetes	203682|Planctomycetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Malectin
TLS3_k127_5115241_2	344747.PM8797T_31653	3.565e-18	94.0	2F8GG@1|root,340VA@2|Bacteria,2J3K0@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5115241_4	743721.Psesu_1571	5.274e-06	58.0	COG4591@1|root,COG4591@2|Bacteria,1Q2BY@1224|Proteobacteria,1RY89@1236|Gammaproteobacteria,1X5I6@135614|Xanthomonadales	135614|Xanthomonadales	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
TLS3_k127_5115241_0	1280663.ATVR01000006_gene2761	4.36e-48	179.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,4BWA1@830|Butyrivibrio	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_5115241_3	1434325.AZQN01000007_gene3125	1.669e-06	53.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,47MDV@768503|Cytophagia	976|Bacteroidetes	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
TLS3_k127_5120641_1	468059.AUHA01000004_gene2086	3.188e-136	458.0	COG2911@1|root,COG3209@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,4NKIP@976|Bacteroidetes,1IW86@117747|Sphingobacteriia	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,Gal_Lectin
TLS3_k127_5120641_3	485918.Cpin_4917	1.841e-35	141.0	2CI8Y@1|root,32XJN@2|Bacteria,4NT82@976|Bacteroidetes,1IY6B@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4402
TLS3_k127_5120641_0	468059.AUHA01000004_gene2088	6.375e-270	872.0	COG3188@1|root,COG3188@2|Bacteria,4NFPY@976|Bacteroidetes,1IWZC@117747|Sphingobacteriia	976|Bacteroidetes	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5120641_2	1408473.JHXO01000005_gene1679	3.771e-79	275.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,2FPUC@200643|Bacteroidia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_5122350_1	521097.Coch_1784	4.799e-103	347.0	COG2843@1|root,COG2843@2|Bacteria,4NI5N@976|Bacteroidetes,1I6CZ@117743|Flavobacteriia,1EQ3C@1016|Capnocytophaga	976|Bacteroidetes	M	capsule biosynthesis protein CapA	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
TLS3_k127_5122350_2	909663.KI867150_gene2054	1.462e-81	277.0	COG2836@1|root,COG2836@2|Bacteria,1QVGG@1224|Proteobacteria,432GS@68525|delta/epsilon subdivisions,2WXZW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
TLS3_k127_5122350_3	1408473.JHXO01000006_gene1272	1.144e-61	219.0	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,2FM8F@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
TLS3_k127_5122350_0	869213.JCM21142_93397	2.791e-213	669.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,47JQ7@768503|Cytophagia	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
TLS3_k127_5122350_4	927658.AJUM01000037_gene2377	9.94e-33	133.0	COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,2FPIN@200643|Bacteroidia,3XJ1Q@558415|Marinilabiliaceae	976|Bacteroidetes	O	GrpE	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
TLS3_k127_5125663_8	357276.EL88_21570	4.587e-05	46.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,2FMBR@200643|Bacteroidia,4AN8T@815|Bacteroidaceae	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
TLS3_k127_5125663_5	927658.AJUM01000037_gene2262	6.521e-86	293.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,2FNUF@200643|Bacteroidia,3XIQ3@558415|Marinilabiliaceae	976|Bacteroidetes	U	Sec-independent protein translocase protein (TatC)	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
TLS3_k127_5125663_3	1408473.JHXO01000010_gene3560	8.32e-114	371.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,2FKZE@200643|Bacteroidia	976|Bacteroidetes	S	ABC transporter, ATP-binding protein	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
TLS3_k127_5125663_2	886379.AEWI01000023_gene4	4.72e-116	388.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,2FM7B@200643|Bacteroidia,3XJQX@558415|Marinilabiliaceae	976|Bacteroidetes	O	Bacterial trigger factor protein (TF)	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
TLS3_k127_5125663_4	1121129.KB903359_gene2267	2.618e-110	360.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,2FN8E@200643|Bacteroidia,22W88@171551|Porphyromonadaceae	976|Bacteroidetes	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
TLS3_k127_5125663_0	385682.AFSL01000060_gene1758	7.972e-202	636.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,2FMQV@200643|Bacteroidia,3XIWM@558415|Marinilabiliaceae	976|Bacteroidetes	O	ClpX C4-type zinc finger	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
TLS3_k127_5125663_7	1408473.JHXO01000010_gene3588	5.054e-42	160.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,2FT42@200643|Bacteroidia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
TLS3_k127_5125663_1	1509405.GV67_17385	4.823e-137	439.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2TQSB@28211|Alphaproteobacteria,4BB11@82115|Rhizobiaceae	28211|Alphaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
TLS3_k127_5125663_6	869213.JCM21142_505	4.933e-63	222.0	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,47KJI@768503|Cytophagia	976|Bacteroidetes	L	PFAM Uncharacterised ACR, COG1259	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
TLS3_k127_5152723_3	314225.ELI_11625	5.224e-14	76.0	2EG8Z@1|root,33A0S@2|Bacteria,1NKBI@1224|Proteobacteria,2UN0S@28211|Alphaproteobacteria,2K67X@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5152723_1	929556.Solca_2863	1.229e-50	185.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,4NFYC@976|Bacteroidetes,1IPQ6@117747|Sphingobacteriia	976|Bacteroidetes	FL	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
TLS3_k127_5152723_2	1123008.KB905694_gene1564	3.698e-31	127.0	COG4430@1|root,COG4430@2|Bacteria,4NQAJ@976|Bacteroidetes	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
TLS3_k127_5152723_0	1408473.JHXO01000006_gene1174	1.131e-218	700.0	COG1629@1|root,COG4771@2|Bacteria,4NEHN@976|Bacteroidetes,2FNEZ@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_5167769_1	563031.HMPREF0666_02406	4.365e-12	66.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,2FMFA@200643|Bacteroidia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
TLS3_k127_5167769_0	1408473.JHXO01000010_gene3781	0.0	1325.0	COG3250@1|root,COG3250@2|Bacteria,4NE7H@976|Bacteroidetes,2FNT8@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
TLS3_k127_5211153_2	694427.Palpr_1633	2.074e-82	277.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,2FM0P@200643|Bacteroidia,22W8R@171551|Porphyromonadaceae	976|Bacteroidetes	G	beta-galactosidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
TLS3_k127_5211153_1	1408473.JHXO01000002_gene3926	1.28e-171	547.0	COG0738@1|root,COG0738@2|Bacteria,4NEB2@976|Bacteroidetes,2FMGI@200643|Bacteroidia	976|Bacteroidetes	G	Transporter, major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_5211153_0	742767.HMPREF9456_00110	7.961e-320	992.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,2FQHJ@200643|Bacteroidia,22XIE@171551|Porphyromonadaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
TLS3_k127_5211153_3	880071.Fleli_1916	3.391e-52	195.0	COG1807@1|root,COG1807@2|Bacteria,4NHXW@976|Bacteroidetes,47MJ3@768503|Cytophagia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_5211611_6	869213.JCM21142_72658	2.402e-125	408.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_5211611_9	234267.Acid_5538	6.029e-104	351.0	COG3828@1|root,COG3828@2|Bacteria,3Y61V@57723|Acidobacteria	57723|Acidobacteria	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
TLS3_k127_5211611_10	869213.JCM21142_72651	7.042e-100	334.0	COG0463@1|root,COG0463@2|Bacteria,4NGGM@976|Bacteroidetes,47JIX@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
TLS3_k127_5211611_7	927658.AJUM01000034_gene442	9.968e-120	409.0	COG0457@1|root,COG1287@1|root,COG0457@2|Bacteria,COG1287@2|Bacteria,4PNYV@976|Bacteroidetes,2FWP6@200643|Bacteroidia	976|Bacteroidetes	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT,TPR_19,TPR_8
TLS3_k127_5211611_1	761193.Runsl_4442	3.937e-166	527.0	COG0388@1|root,COG0388@2|Bacteria,4NGWX@976|Bacteroidetes,47JH4@768503|Cytophagia	976|Bacteroidetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
TLS3_k127_5211611_11	1123008.KB905699_gene1903	8.02e-89	302.0	COG1082@1|root,COG1082@2|Bacteria,4NFQY@976|Bacteroidetes	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_5211611_2	869213.JCM21142_72652	3.378e-165	526.0	COG0673@1|root,COG0673@2|Bacteria,4NFMS@976|Bacteroidetes,47K95@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_5211611_4	1168034.FH5T_02400	5.685e-138	450.0	COG0738@1|root,COG0738@2|Bacteria,4NFTC@976|Bacteroidetes	976|Bacteroidetes	G	Pfam Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_5211611_0	869213.JCM21142_72653	1.028e-167	531.0	COG1082@1|root,COG1082@2|Bacteria,4NGBE@976|Bacteroidetes,47M7V@768503|Cytophagia	976|Bacteroidetes	G	AP endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
TLS3_k127_5211611_8	1408473.JHXO01000006_gene1391	6.804e-111	363.0	COG0778@1|root,COG0778@2|Bacteria,4NJ80@976|Bacteroidetes,2FNX6@200643|Bacteroidia	976|Bacteroidetes	C	Nitroreductase family	-	-	1.5.1.38,1.5.1.39	ko:K19285,ko:K19286	ko00740,ko01100,map00740,map01100	-	R05705,R05706	RC00126	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
TLS3_k127_5211611_5	1121373.KB903628_gene1393	3.578e-134	436.0	COG2055@1|root,COG2055@2|Bacteria,4NGVC@976|Bacteroidetes,47KBZ@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
TLS3_k127_5211611_3	925409.KI911562_gene1370	3.847e-153	488.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IR3P@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
TLS3_k127_5224190_5	1304888.ATWF01000001_gene1391	0.0006042	51.0	COG4886@1|root,COG5492@1|root,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF1570,DUF4430,LRR_5,Laminin_G_3
TLS3_k127_5224190_3	929556.Solca_2236	5.677e-32	129.0	COG2010@1|root,COG2010@2|Bacteria,4NRFW@976|Bacteroidetes,1IU4G@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
TLS3_k127_5224190_1	1168034.FH5T_16955	3.701e-56	203.0	COG4117@1|root,COG4117@2|Bacteria	2|Bacteria	C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)	ydhU	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03620,ko:K08354	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10149	RC02823	ko00000,ko00001,ko02000	5.A.3.5	-	-	Cytochrome_C7,Ni_hydr_CYTB
TLS3_k127_5224190_0	1168034.FH5T_16960	2.099e-79	276.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
TLS3_k127_5224190_2	1121875.KB907546_gene2676	8.87e-52	194.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1I0TY@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5224190_4	1121875.KB907546_gene2677	1.725e-12	71.0	COG2010@1|root,COG2010@2|Bacteria,4NX4D@976|Bacteroidetes,1I5CI@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5250147_0	1380384.JADN01000003_gene400	3.603e-110	364.0	COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,1HXSE@117743|Flavobacteriia	976|Bacteroidetes	EH	Anthranilate synthase	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
TLS3_k127_5250147_2	869213.JCM21142_72939	7.665e-75	256.0	COG0512@1|root,COG0512@2|Bacteria,4NE4I@976|Bacteroidetes,47JZQ@768503|Cytophagia	976|Bacteroidetes	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase	pabA	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
TLS3_k127_5250147_1	869213.JCM21142_72940	3.692e-110	365.0	COG0547@1|root,COG0547@2|Bacteria,4NH2J@976|Bacteroidetes,47KKR@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
TLS3_k127_5260292_0	1168289.AJKI01000002_gene2701	5.001e-136	461.0	COG0755@1|root,COG0755@2|Bacteria,4NDY1@976|Bacteroidetes,2FKZ1@200643|Bacteroidia,3XITP@558415|Marinilabiliaceae	976|Bacteroidetes	O	Cytochrome C assembly protein	ccsA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
TLS3_k127_5260292_1	1168034.FH5T_16980	2.757e-33	137.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	Z012_05310	-	-	ko:K01420,ko:K10914,ko:K21556,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TLS3_k127_5260292_2	1168034.FH5T_16975	4.221e-14	83.0	2DRZU@1|root,33DVD@2|Bacteria,4P3PD@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5260398_1	1379698.RBG1_1C00001G1080	2.889e-144	485.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_5260398_0	1120965.AUBV01000008_gene2018	1.691e-221	708.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47JK5@768503|Cytophagia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_5268403_3	1278307.KB906974_gene1805	1.067e-38	153.0	COG0300@1|root,COG0300@2|Bacteria,1MZSS@1224|Proteobacteria,1S9D8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_5268403_2	655815.ZPR_0338	1.637e-65	235.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,1HYCJ@117743|Flavobacteriia	976|Bacteroidetes	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_5268403_0	760192.Halhy_2292	3.232e-144	474.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,1IRN9@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase M1 membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,Peptidase_M1
TLS3_k127_5268403_1	1211813.CAPH01000013_gene416	3.972e-131	425.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,2FPBU@200643|Bacteroidia,22UUK@171550|Rikenellaceae	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
TLS3_k127_5271520_1	869213.JCM21142_114580	8.028e-152	489.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,47KM0@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
TLS3_k127_5271520_2	694427.Palpr_2974	2.474e-150	484.0	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,2FMGB@200643|Bacteroidia,22W16@171551|Porphyromonadaceae	976|Bacteroidetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS3_k127_5271520_4	1500890.JQNL01000001_gene1854	2.935e-36	154.0	COG2755@1|root,COG2755@2|Bacteria,1RBFJ@1224|Proteobacteria,1SEW9@1236|Gammaproteobacteria,1X661@135614|Xanthomonadales	135614|Xanthomonadales	E	COG2755 Lysophospholipase L1 and related esterases	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS3_k127_5271520_3	1168034.FH5T_09895	2.799e-64	238.0	COG0584@1|root,COG0584@2|Bacteria,4NMGN@976|Bacteroidetes,2FP5M@200643|Bacteroidia	976|Bacteroidetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
TLS3_k127_5271520_5	269797.Mbar_A1915	1.396e-08	65.0	COG3291@1|root,arCOG02540@1|root,arCOG02510@2157|Archaea,arCOG02540@2157|Archaea	2157|Archaea	O	Belongs to the peptidase C1 family	-	-	-	-	-	-	-	-	-	-	-	-	PKD
TLS3_k127_5271520_0	1168289.AJKI01000030_gene1157	2.721e-215	674.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,2FMAU@200643|Bacteroidia,3XJJD@558415|Marinilabiliaceae	976|Bacteroidetes	J	Threonyl and Alanyl tRNA synthetase second additional domain	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
TLS3_k127_5275411_2	1124780.ANNU01000032_gene1222	8.449e-44	163.0	COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,47XKT@768503|Cytophagia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
TLS3_k127_5275411_1	1124780.ANNU01000032_gene1223	2.747e-127	418.0	COG0845@1|root,COG0845@2|Bacteria,4NF0X@976|Bacteroidetes,47U0H@768503|Cytophagia	976|Bacteroidetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
TLS3_k127_5275411_0	926559.JoomaDRAFT_3525	0.0	1463.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS3_k127_5293471_4	927658.AJUM01000042_gene1740	6.745e-117	382.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,2FPBU@200643|Bacteroidia,3XJ9Z@558415|Marinilabiliaceae	976|Bacteroidetes	J	tRNA methyl transferase	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
TLS3_k127_5293471_0	742766.HMPREF9455_00984	6.848e-221	722.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,2FMHG@200643|Bacteroidia,22W5V@171551|Porphyromonadaceae	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
TLS3_k127_5293471_3	742725.HMPREF9450_01095	5.194e-121	395.0	COG1242@1|root,COG1242@2|Bacteria,4NGK6@976|Bacteroidetes,2FPR8@200643|Bacteroidia,22U4X@171550|Rikenellaceae	976|Bacteroidetes	S	Radical SAM protein	-	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
TLS3_k127_5293471_1	641524.ADICYQ_0727	5.528e-190	607.0	28HHT@1|root,2Z7TE@2|Bacteria,4NIHS@976|Bacteroidetes,47MAA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5293471_2	1408473.JHXO01000008_gene2789	7.391e-182	603.0	COG2887@1|root,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,2FN03@200643|Bacteroidia	976|Bacteroidetes	L	DNA-dependent ATPase I and helicase II	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
TLS3_k127_5293471_5	1408473.JHXO01000008_gene2783	1.101e-65	228.0	COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes,2FNGS@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
TLS3_k127_5293471_6	1408473.JHXO01000008_gene2782	4.768e-59	210.0	COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,2G3E7@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
TLS3_k127_529939_0	762968.HMPREF9441_01018	1.398e-105	350.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,2FMDB@200643|Bacteroidia	976|Bacteroidetes	E	homoserine dehydrogenase	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
TLS3_k127_529939_1	1499967.BAYZ01000045_gene2649	8.785e-97	323.0	COG0498@1|root,COG0498@2|Bacteria,2NQNZ@2323|unclassified Bacteria	2|Bacteria	E	Threonine synthase N terminus	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025	PALP,Thr_synth_N
TLS3_k127_5301582_3	1168289.AJKI01000040_gene3115	4.493e-38	156.0	COG0823@1|root,COG0823@2|Bacteria,4PJFQ@976|Bacteroidetes,2G2AK@200643|Bacteroidia,3XKMZ@558415|Marinilabiliaceae	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_5301582_2	1408473.JHXO01000006_gene1150	1.092e-56	202.0	COG1670@1|root,COG1670@2|Bacteria,4NQ8K@976|Bacteroidetes,2FMII@200643|Bacteroidia	976|Bacteroidetes	J	Acetyltransferase, gnat family	speG	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
TLS3_k127_5301582_1	385682.AFSL01000003_gene1899	5.383e-88	301.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,2FPJH@200643|Bacteroidia,3XINF@558415|Marinilabiliaceae	976|Bacteroidetes	J	Radical SAM superfamily	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
TLS3_k127_5301582_0	1047013.AQSP01000027_gene2317	9.91e-260	818.0	COG0339@1|root,COG0339@2|Bacteria,2NP9Q@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M3	prlC	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
TLS3_k127_5314222_2	709991.Odosp_2729	1.981e-95	321.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,2FM0W@200643|Bacteroidia,22W1I@171551|Porphyromonadaceae	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
TLS3_k127_5314222_8	1185876.BN8_01155	0.000228	46.0	COG1977@1|root,COG1977@2|Bacteria,4NUVK@976|Bacteroidetes,47RZY@768503|Cytophagia	976|Bacteroidetes	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
TLS3_k127_5314222_0	484018.BACPLE_00233	1.641e-307	968.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,2FM8X@200643|Bacteroidia,4AKN4@815|Bacteroidaceae	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
TLS3_k127_5314222_6	1203611.KB894543_gene1725	3.213e-52	188.0	COG0720@1|root,COG0720@2|Bacteria,4NM8H@976|Bacteroidetes,2FU4Q@200643|Bacteroidia,22UI1@171550|Rikenellaceae	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
TLS3_k127_5314222_1	1408473.JHXO01000006_gene1019	1.752e-198	632.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,2FR3T@200643|Bacteroidia	976|Bacteroidetes	I	Long-chain acyl-CoA synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
TLS3_k127_5314222_3	886379.AEWI01000066_gene2341	1.211e-86	292.0	COG0605@1|root,COG0605@2|Bacteria,4P18A@976|Bacteroidetes,2FW9K@200643|Bacteroidia,3XJJ9@558415|Marinilabiliaceae	976|Bacteroidetes	P	Iron/manganese superoxide dismutases, alpha-hairpin domain	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
TLS3_k127_5314222_7	694427.Palpr_2930	1.075e-26	113.0	COG4270@1|root,COG4270@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
TLS3_k127_5314222_4	1168034.FH5T_09785	2.615e-70	246.0	COG1999@1|root,COG1999@2|Bacteria,4NU1J@976|Bacteroidetes,2FXFP@200643|Bacteroidia	976|Bacteroidetes	S	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
TLS3_k127_5314222_5	694427.Palpr_2932	3.221e-65	226.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,2FXCG@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
TLS3_k127_5315336_1	1122176.KB903535_gene2024	1.425e-37	146.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_5315336_2	395965.Msil_2286	2.774e-08	66.0	COG0457@1|root,COG0457@2|Bacteria,1NG0U@1224|Proteobacteria,2U0YA@28211|Alphaproteobacteria,3N9KN@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
TLS3_k127_5315336_0	1288963.ADIS_3658	8.988e-111	376.0	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,4PM99@976|Bacteroidetes,47Y55@768503|Cytophagia	976|Bacteroidetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg,Y_Y_Y
TLS3_k127_5329910_1	1168289.AJKI01000036_gene3400	6.318e-57	206.0	2CESB@1|root,2Z8UZ@2|Bacteria,4NJSJ@976|Bacteroidetes	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5329910_0	1408473.JHXO01000009_gene3427	7.257e-95	323.0	COG3214@1|root,COG3214@2|Bacteria,4NGF2@976|Bacteroidetes,2FP5R@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG15865 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
TLS3_k127_5347891_6	523791.Kkor_0141	1.123e-98	323.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,1XHIJ@135619|Oceanospirillales	135619|Oceanospirillales	O	Alkyl hydroperoxide reductase	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
TLS3_k127_5347891_11	42565.FP66_14830	7.639e-68	242.0	COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,1RNC7@1236|Gammaproteobacteria,1XI31@135619|Oceanospirillales	135619|Oceanospirillales	O	alkyl hydroperoxide reductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
TLS3_k127_5347891_16	929713.NIASO_03755	1.753e-11	70.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,1IXCE@117747|Sphingobacteriia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
TLS3_k127_5347891_0	385682.AFSL01000006_gene2345	1.2e-268	843.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,2FNKB@200643|Bacteroidia,3XJMH@558415|Marinilabiliaceae	976|Bacteroidetes	L	RecG wedge domain	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
TLS3_k127_5347891_14	1168034.FH5T_16610	3.466e-18	89.0	COG3086@1|root,COG3086@2|Bacteria,4NV0R@976|Bacteroidetes,2FS4Y@200643|Bacteroidia	976|Bacteroidetes	T	Positive regulator of sigma(E), RseC MucC	-	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
TLS3_k127_5347891_5	709991.Odosp_1400	5.928e-119	389.0	COG1148@1|root,COG2878@1|root,COG1148@2|Bacteria,COG2878@2|Bacteria,4NFEB@976|Bacteroidetes,2FMPN@200643|Bacteroidia,22XEE@171551|Porphyromonadaceae	976|Bacteroidetes	C	Ferredoxin	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4
TLS3_k127_5347891_1	869213.JCM21142_93460	2.736e-194	614.0	COG4656@1|root,COG4656@2|Bacteria,4NIS7@976|Bacteroidetes	976|Bacteroidetes	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,Fer4_7,RnfC_N,SLBB
TLS3_k127_5347891_3	1168289.AJKI01000031_gene1115	2.509e-136	441.0	COG4658@1|root,COG4658@2|Bacteria,4NESE@976|Bacteroidetes,2FM2Y@200643|Bacteroidia,3XIVH@558415|Marinilabiliaceae	976|Bacteroidetes	C	NQR2, RnfD, RnfE family	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
TLS3_k127_5347891_12	869213.JCM21142_93462	4.889e-54	195.0	COG4659@1|root,COG4659@2|Bacteria,4NP1D@976|Bacteroidetes	976|Bacteroidetes	C	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
TLS3_k127_5347891_8	1121904.ARBP01000002_gene6739	2.684e-80	271.0	COG4660@1|root,COG4660@2|Bacteria,4NHHP@976|Bacteroidetes	976|Bacteroidetes	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
TLS3_k127_5347891_9	869213.JCM21142_93464	9.751e-80	271.0	COG4657@1|root,COG4657@2|Bacteria,4NGEZ@976|Bacteroidetes,47XMF@768503|Cytophagia	976|Bacteroidetes	U	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
TLS3_k127_5347891_15	1291743.LOSG293_210020	2.174e-12	74.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,3F490@33958|Lactobacillaceae	91061|Bacilli	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
TLS3_k127_5347891_7	1123008.KB905695_gene2562	6.58e-86	299.0	COG4826@1|root,COG4826@2|Bacteria,4NG1G@976|Bacteroidetes,2FR07@200643|Bacteroidia,22WP3@171551|Porphyromonadaceae	976|Bacteroidetes	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
TLS3_k127_5347891_10	935837.JAEK01000041_gene3782	3.968e-69	244.0	COG1409@1|root,COG1409@2|Bacteria,1VMBT@1239|Firmicutes,4HUFU@91061|Bacilli	91061|Bacilli	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
TLS3_k127_5347891_13	1168289.AJKI01000042_gene3700	1.878e-24	108.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,2G24U@200643|Bacteroidia,3XK3Q@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
TLS3_k127_5347891_2	927658.AJUM01000042_gene1726	2.808e-153	490.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,2FKZ9@200643|Bacteroidia,3XJP3@558415|Marinilabiliaceae	976|Bacteroidetes	O	Glycoprotease family	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
TLS3_k127_5347891_4	1408473.JHXO01000004_gene166	2.249e-122	431.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,2FNBJ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location OuterMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	TamB
TLS3_k127_5351020_3	1408473.JHXO01000007_gene782	2.138e-44	168.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,2FKYN@200643|Bacteroidia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
TLS3_k127_5351020_1	880070.Cycma_0164	7.212e-137	441.0	COG1082@1|root,COG1082@2|Bacteria,4NI4H@976|Bacteroidetes,47MMY@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_5351020_2	1300143.CCAV010000005_gene3854	2.102e-130	430.0	COG3292@1|root,COG5184@1|root,COG3292@2|Bacteria,COG5184@2|Bacteria,4PHXH@976|Bacteroidetes,1I73G@117743|Flavobacteriia,3ZUBQ@59732|Chryseobacterium	976|Bacteroidetes	DTZ	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,Reg_prop
TLS3_k127_5351020_0	927658.AJUM01000017_gene3083	3.413e-223	701.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,2FW95@200643|Bacteroidia,3XIXS@558415|Marinilabiliaceae	976|Bacteroidetes	L	DNA polymerase alpha chain like domain	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
TLS3_k127_5384564_2	742726.HMPREF9448_00671	6.979e-56	199.0	COG1595@1|root,COG1595@2|Bacteria,4NMM3@976|Bacteroidetes,2FNH5@200643|Bacteroidia,22XTV@171551|Porphyromonadaceae	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_5384564_1	984262.SGRA_2418	1.181e-63	229.0	COG2267@1|root,COG2267@2|Bacteria,4NIU9@976|Bacteroidetes	976|Bacteroidetes	I	Alpha beta hydrolase	ytpA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
TLS3_k127_5384564_0	470145.BACCOP_01050	1.326e-82	285.0	COG2755@1|root,COG2755@2|Bacteria,4NFN6@976|Bacteroidetes,2FKZ2@200643|Bacteroidia,4AKGA@815|Bacteroidaceae	976|Bacteroidetes	E	GSCFA family	-	-	-	-	-	-	-	-	-	-	-	-	GSCFA
TLS3_k127_5384564_3	1380384.JADN01000006_gene2538	5.269e-09	61.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1HXF4@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_5389728_0	743722.Sph21_3174	5.991e-86	289.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,4NF9S@976|Bacteroidetes,1IPJD@117747|Sphingobacteriia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
TLS3_k127_5389728_2	1408473.JHXO01000001_gene2237	3.905e-41	154.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,2FMSF@200643|Bacteroidia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
TLS3_k127_5389728_1	1349785.BAUG01000018_gene1335	1.833e-50	190.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1HWNN@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	fjo29	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS3_k127_5419438_3	1380600.AUYN01000009_gene2113	3.439e-07	52.0	28HII@1|root,2Z7TZ@2|Bacteria,4NHR6@976|Bacteroidetes,1HZ5D@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5419438_1	1123008.KB905693_gene1483	2.774e-107	353.0	COG0287@1|root,COG0287@2|Bacteria,4NGI9@976|Bacteroidetes	976|Bacteroidetes	E	Phosphogluconate dehydrogenase (decarboxylating) C-term	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_2,PGDH_C
TLS3_k127_5419438_0	1123008.KB905693_gene1482	2.158e-159	508.0	COG0673@1|root,COG0673@2|Bacteria,4NE07@976|Bacteroidetes,2FNUN@200643|Bacteroidia,22X96@171551|Porphyromonadaceae	976|Bacteroidetes	S	Oxidoreductase NAD-binding domain protein	gfo_1	-	1.1.1.384	ko:K13327,ko:K22230	ko00523,ko00562,ko01120,ko01130,map00523,map00562,map01120,map01130	M00801,M00802	R05526,R09954	RC00182,RC00897	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_5419438_2	1123008.KB905693_gene1480	5.339e-42	155.0	COG4975@1|root,COG4975@2|Bacteria,4NF22@976|Bacteroidetes,2FMYN@200643|Bacteroidia,22X3I@171551|Porphyromonadaceae	976|Bacteroidetes	G	Sugar transport protein	-	-	-	ko:K05340	-	-	-	-	ko00000,ko02000	2.A.7.5	-	-	Ureide_permease
TLS3_k127_5430627_0	869213.JCM21142_42047	2.046e-147	471.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,47KS2@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
TLS3_k127_5430627_1	886379.AEWI01000013_gene2101	1.794e-65	226.0	COG1781@1|root,COG1781@2|Bacteria,4NR6N@976|Bacteroidetes,2FRZM@200643|Bacteroidia,3XJZK@558415|Marinilabiliaceae	976|Bacteroidetes	F	Aspartate carbamoyltransferase regulatory chain, metal binding domain	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
TLS3_k127_5430627_2	1123279.ATUS01000001_gene1280	5.828e-27	122.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,1RWCX@1236|Gammaproteobacteria,1J71A@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
TLS3_k127_5430627_3	470145.BACCOP_03414	4.782e-11	69.0	2E8SV@1|root,3333M@2|Bacteria,4NSHV@976|Bacteroidetes,2FV1F@200643|Bacteroidia,4AQMH@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4293
TLS3_k127_5432293_2	700598.Niako_0752	2.159e-27	113.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1INZB@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
TLS3_k127_5432293_0	700598.Niako_0751	1.548e-309	963.0	COG3661@1|root,COG3661@2|Bacteria,4NHE2@976|Bacteroidetes,1IPVK@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 67 family	aguA	-	3.2.1.139	ko:K01235	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_67C,Glyco_hydro_67M,Glyco_hydro_67N
TLS3_k127_5432293_1	555500.I215_08121	3.113e-89	302.0	COG1028@1|root,COG1028@2|Bacteria,4NIH6@976|Bacteroidetes,1IIGH@117743|Flavobacteriia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
TLS3_k127_5452778_3	869213.JCM21142_41848	2.582e-39	163.0	COG1388@1|root,COG1388@2|Bacteria,4NG96@976|Bacteroidetes	976|Bacteroidetes	M	LysM domain	lysM	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
TLS3_k127_5452778_2	313606.M23134_01323	2.449e-47	176.0	COG1595@1|root,COG1595@2|Bacteria,4NQTP@976|Bacteroidetes,47QT5@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_5452778_0	1408473.JHXO01000001_gene2062	2.212e-166	549.0	COG0457@1|root,COG0457@2|Bacteria,4NFFS@976|Bacteroidetes,2FMYG@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_16,TPR_19,TPR_6,TPR_7,TPR_8
TLS3_k127_5452778_1	755732.Fluta_1237	7.893e-107	353.0	COG1032@1|root,COG1032@2|Bacteria,4NGYA@976|Bacteroidetes,1I02A@117743|Flavobacteriia,2PBIF@246874|Cryomorphaceae	976|Bacteroidetes	C	Domain of unknown function (DUF3362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
TLS3_k127_54531_1	1168034.FH5T_10330	2.483e-116	380.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,2FNBV@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
TLS3_k127_54531_2	869213.JCM21142_516	1.581e-84	286.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,47KKV@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
TLS3_k127_54531_0	869213.JCM21142_517	2.304e-213	676.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,47MAC@768503|Cytophagia	976|Bacteroidetes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
TLS3_k127_54531_3	926562.Oweho_1820	2.73e-07	57.0	COG1555@1|root,COG1555@2|Bacteria,4NQC1@976|Bacteroidetes,1IBFS@117743|Flavobacteriia,2PB2U@246874|Cryomorphaceae	976|Bacteroidetes	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5468358_0	762903.Pedsa_3731	3.86e-184	590.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,1IQ13@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
TLS3_k127_5468358_1	1235803.C825_02900	7.016e-27	112.0	COG3420@1|root,COG3420@2|Bacteria,4NF5Y@976|Bacteroidetes,2FPPC@200643|Bacteroidia,2316W@171551|Porphyromonadaceae	976|Bacteroidetes	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TLS3_k127_5478094_4	927658.AJUM01000037_gene1834	1.974e-58	205.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
TLS3_k127_5478094_1	927658.AJUM01000034_gene103	7.931e-188	597.0	COG0493@1|root,COG0493@2|Bacteria,4NG9R@976|Bacteroidetes,2FN6R@200643|Bacteroidia,3XJBN@558415|Marinilabiliaceae	976|Bacteroidetes	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
TLS3_k127_5478094_0	869213.JCM21142_333	0.0	1922.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,47JB7@768503|Cytophagia	976|Bacteroidetes	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
TLS3_k127_5478094_5	1123276.KB893265_gene4526	0.0004736	42.0	COG0823@1|root,COG0823@2|Bacteria,4NQIN@976|Bacteroidetes,47QV9@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_5478094_2	1121129.KB903359_gene1289	7.024e-114	385.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,2FP6P@200643|Bacteroidia,22XC3@171551|Porphyromonadaceae	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
TLS3_k127_5478094_3	385682.AFSL01000095_gene818	3.087e-81	275.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,2FNS0@200643|Bacteroidia,3XJFZ@558415|Marinilabiliaceae	976|Bacteroidetes	H	GTP cyclohydrolase II	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
TLS3_k127_5479507_5	1408473.JHXO01000017_gene2951	1.441e-129	428.0	2CESB@1|root,2Z8UZ@2|Bacteria,4NJSJ@976|Bacteroidetes,2FXQC@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
TLS3_k127_5479507_7	1168034.FH5T_09605	1.889e-108	359.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,2FNWR@200643|Bacteroidia	976|Bacteroidetes	G	COG COG1082 Sugar phosphate isomerases epimerases	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_5479507_8	616991.JPOO01000003_gene119	7.257e-104	349.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,1HYFP@117743|Flavobacteriia,23GX1@178469|Arenibacter	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
TLS3_k127_5479507_2	694427.Palpr_2283	1.124e-215	680.0	COG3669@1|root,COG3669@2|Bacteria,4NEAP@976|Bacteroidetes,2FM7K@200643|Bacteroidia,22Y2X@171551|Porphyromonadaceae	976|Bacteroidetes	G	Alpha-L-fucosidase C-terminal domain	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
TLS3_k127_5479507_10	1197477.IA57_00610	2.427e-22	104.0	28P8J@1|root,2ZC2G@2|Bacteria,4NTQZ@976|Bacteroidetes,1I3WF@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5479507_3	1122605.KB893625_gene1898	4.576e-212	680.0	COG3458@1|root,COG3458@2|Bacteria,4NJMX@976|Bacteroidetes	976|Bacteroidetes	Q	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
TLS3_k127_5479507_6	1121481.AUAS01000006_gene577	4.311e-125	409.0	COG0673@1|root,COG0673@2|Bacteria,4NHFK@976|Bacteroidetes,47MBN@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_5479507_1	388413.ALPR1_11290	1.18e-222	697.0	COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,47M0H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_5479507_4	1123248.KB893342_gene848	1.584e-135	441.0	2DBNR@1|root,2ZA54@2|Bacteria,4NHW9@976|Bacteroidetes,1IRGS@117747|Sphingobacteriia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
TLS3_k127_5479507_9	762903.Pedsa_2048	3.187e-95	317.0	COG2755@1|root,COG2755@2|Bacteria,4NMUB@976|Bacteroidetes,1IQT1@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Lipase, GDSL	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS3_k127_5479507_0	1408473.JHXO01000005_gene1675	2.458e-270	850.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FNZH@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	bglB	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
TLS3_k127_550917_2	649349.Lbys_1615	9.499e-127	415.0	COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,47JBJ@768503|Cytophagia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	exuT	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
TLS3_k127_550917_3	886379.AEWI01000001_gene1812	6.214e-95	326.0	COG1609@1|root,COG1609@2|Bacteria,4NE81@976|Bacteroidetes,2FN0D@200643|Bacteroidia,3XJ3R@558415|Marinilabiliaceae	976|Bacteroidetes	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_4
TLS3_k127_550917_0	886379.AEWI01000001_gene1813	7.522e-169	539.0	2BXG3@1|root,2Z82R@2|Bacteria,4NI3Z@976|Bacteroidetes,2FNWQ@200643|Bacteroidia,3XJ3M@558415|Marinilabiliaceae	976|Bacteroidetes	S	tagaturonate epimerase	-	-	5.1.2.7	ko:K21619	ko00040,ko01100,map00040,map01100	-	R11624	-	ko00000,ko00001,ko01000	-	-	-	UxaE
TLS3_k127_550917_1	886379.AEWI01000001_gene1816	1.266e-163	523.0	COG4225@1|root,COG4225@2|Bacteria,4NFWI@976|Bacteroidetes,2FWNU@200643|Bacteroidia,3XJ28@558415|Marinilabiliaceae	976|Bacteroidetes	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
TLS3_k127_5519716_3	1237149.C900_03023	6.862e-06	57.0	COG3307@1|root,COG3307@2|Bacteria,4NUP9@976|Bacteroidetes,47V2J@768503|Cytophagia	976|Bacteroidetes	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
TLS3_k127_5519716_1	563040.Saut_1487	9.742e-78	271.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,42QJJ@68525|delta/epsilon subdivisions,2YMTJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	PFAM Glycosyl transferase, family 4, conserved region	-	-	-	ko:K13007	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
TLS3_k127_5519716_2	1537915.JU57_07995	1.848e-67	239.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,42PPG@68525|delta/epsilon subdivisions,2YR9J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
TLS3_k127_5519716_0	997884.HMPREF1068_03322	3.651e-92	310.0	COG0438@1|root,COG0438@2|Bacteria,4NK2C@976|Bacteroidetes,2G1ZQ@200643|Bacteroidia,4ATB2@815|Bacteroidaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	orfL	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
TLS3_k127_55231_3	908612.HMPREF9720_0597	9.946e-64	222.0	COG0125@1|root,COG0125@2|Bacteria,4NPI5@976|Bacteroidetes,2G1QI@200643|Bacteroidia,22UC8@171550|Rikenellaceae	976|Bacteroidetes	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
TLS3_k127_55231_1	1150600.ADIARSV_1374	4.545e-95	319.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,1IPC6@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
TLS3_k127_55231_2	880526.KE386488_gene161	5.159e-71	248.0	COG1624@1|root,COG1624@2|Bacteria,4NG3Z@976|Bacteroidetes,2FN6K@200643|Bacteroidia,22UCX@171550|Rikenellaceae	976|Bacteroidetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
TLS3_k127_55231_4	585543.HMPREF0969_03455	6.623e-41	160.0	COG2731@1|root,COG2731@2|Bacteria,4NT2J@976|Bacteroidetes,2FNDS@200643|Bacteroidia,4APJM@815|Bacteroidaceae	976|Bacteroidetes	G	COG COG2731 Beta-galactosidase, beta subunit	tabA_1	-	-	-	-	-	-	-	-	-	-	-	DUF386
TLS3_k127_55231_0	694427.Palpr_1465	4.478e-290	911.0	COG0370@1|root,COG1918@1|root,COG0370@2|Bacteria,COG1918@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia,22VWF@171551|Porphyromonadaceae	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
TLS3_k127_5525259_3	1121896.JMLU01000007_gene268	0.0002084	52.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes,1HYQM@117743|Flavobacteriia,2NSEB@237|Flavobacterium	976|Bacteroidetes	D	Sporulation protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
TLS3_k127_5525259_1	1121912.AUHD01000005_gene1746	3.849e-88	299.0	COG2273@1|root,COG2273@2|Bacteria,4NGMJ@976|Bacteroidetes,1HZUY@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
TLS3_k127_5525259_0	1168034.FH5T_12275	1.94e-139	455.0	COG0312@1|root,COG0312@2|Bacteria,4NE1F@976|Bacteroidetes,2FPXY@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 9.26	tldD3	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
TLS3_k127_5536397_0	1408473.JHXO01000008_gene2781	1.079e-117	389.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,2FMHP@200643|Bacteroidia	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
TLS3_k127_5536397_2	1408473.JHXO01000008_gene2780	2.389e-24	105.0	COG5512@1|root,COG5512@2|Bacteria,4NSDR@976|Bacteroidetes,2FUN4@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
TLS3_k127_555541_4	1168289.AJKI01000036_gene3424	5.257e-138	441.0	COG1028@1|root,COG1028@2|Bacteria,4NFDX@976|Bacteroidetes,2FMSH@200643|Bacteroidia,3XIJI@558415|Marinilabiliaceae	976|Bacteroidetes	IQ	KR domain	idnO	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
TLS3_k127_555541_7	869213.JCM21142_104437	4.156e-129	417.0	COG3717@1|root,COG3717@2|Bacteria,4NDUV@976|Bacteroidetes,47K5H@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
TLS3_k127_555541_3	1408473.JHXO01000001_gene2255	4.005e-140	454.0	COG4225@1|root,COG4225@2|Bacteria,4NGSJ@976|Bacteroidetes,2FM7R@200643|Bacteroidia	976|Bacteroidetes	G	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88,Hepar_II_III
TLS3_k127_555541_1	385682.AFSL01000072_gene1318	1.447e-216	680.0	COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes,2FMMW@200643|Bacteroidia,3XJNU@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
TLS3_k127_555541_6	886379.AEWI01000001_gene1805	9.567e-132	424.0	COG1028@1|root,COG1028@2|Bacteria,4NG8R@976|Bacteroidetes,2FMB9@200643|Bacteroidia,3XJY3@558415|Marinilabiliaceae	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
TLS3_k127_555541_2	385682.AFSL01000072_gene1323	2.354e-209	657.0	COG3875@1|root,COG3875@2|Bacteria,4NI4Z@976|Bacteroidetes,2FQM8@200643|Bacteroidia,3XJV1@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
TLS3_k127_555541_8	926549.KI421517_gene2445	2.395e-114	377.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,47MIQ@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_555541_0	927658.AJUM01000022_gene1033	4.504e-269	833.0	COG0362@1|root,COG0362@2|Bacteria,4NG05@976|Bacteroidetes,2FMFW@200643|Bacteroidia,3XIPB@558415|Marinilabiliaceae	976|Bacteroidetes	G	6-phosphogluconate dehydrogenase, C-terminal domain	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
TLS3_k127_555541_5	649349.Lbys_1615	1.359e-136	440.0	COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,47JBJ@768503|Cytophagia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	exuT	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
TLS3_k127_55689_0	880070.Cycma_2892	1.192e-103	344.0	COG4677@1|root,COG4677@2|Bacteria,4NEEI@976|Bacteroidetes,47P42@768503|Cytophagia	976|Bacteroidetes	G	Pectic acid lyase	pelA	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Pec_lyase,Pectinesterase
TLS3_k127_55689_1	660470.Theba_0060	5.006e-58	219.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
TLS3_k127_55689_2	760192.Halhy_3515	1.835e-08	55.0	COG3386@1|root,COG3386@2|Bacteria,4NH7B@976|Bacteroidetes,1IP9W@117747|Sphingobacteriia	976|Bacteroidetes	G	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
TLS3_k127_5575663_4	1158294.JOMI01000002_gene2928	1.665e-60	214.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,2FN2D@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
TLS3_k127_5575663_5	411901.BACCAC_01420	4.742e-43	168.0	COG0084@1|root,COG0084@2|Bacteria,4NSGW@976|Bacteroidetes,2FQ90@200643|Bacteroidia,4ANH4@815|Bacteroidaceae	976|Bacteroidetes	L	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
TLS3_k127_5575663_2	1168289.AJKI01000002_gene2634	6.118e-80	273.0	COG1179@1|root,COG1179@2|Bacteria,4NEKB@976|Bacteroidetes,2FMG4@200643|Bacteroidia,3XIVJ@558415|Marinilabiliaceae	976|Bacteroidetes	H	ThiF family	hypB	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
TLS3_k127_5575663_0	1047013.AQSP01000105_gene1439	2.103e-177	566.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	MA20_31530	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
TLS3_k127_5575663_3	1121875.KB907549_gene2073	1.588e-78	268.0	COG4122@1|root,COG4122@2|Bacteria,4NM4M@976|Bacteroidetes,1I5WV@117743|Flavobacteriia	976|Bacteroidetes	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
TLS3_k127_5575663_1	1232437.KL662016_gene1079	5.265e-111	368.0	COG3568@1|root,COG3568@2|Bacteria,1RJX3@1224|Proteobacteria,42XMX@68525|delta/epsilon subdivisions,2WTAN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_5575663_6	1120951.AUBG01000005_gene2179	8.323e-09	63.0	2DM37@1|root,31I5W@2|Bacteria,4NQWF@976|Bacteroidetes,1I371@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TerB
TLS3_k127_5577316_8	742767.HMPREF9456_02316	2.599e-11	66.0	COG0842@1|root,COG0842@2|Bacteria,4NKB0@976|Bacteroidetes,2FW5E@200643|Bacteroidia	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
TLS3_k127_5577316_2	1408473.JHXO01000012_gene318	1.203e-125	409.0	COG1131@1|root,COG1131@2|Bacteria,4NMN9@976|Bacteroidetes	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_5577316_3	877415.JNJQ01000025_gene2621	1.436e-88	297.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,3VNZH@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
TLS3_k127_5577316_7	929562.Emtol_0904	1.179e-22	105.0	arCOG14808@1|root,308PC@2|Bacteria,4NR4D@976|Bacteroidetes,47PEP@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
TLS3_k127_5577316_5	1121904.ARBP01000012_gene1244	1.103e-69	250.0	28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5577316_0	1408473.JHXO01000011_gene2976	1.836e-267	833.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,2FMXC@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
TLS3_k127_5577316_4	1168034.FH5T_19710	1.212e-74	260.0	COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_5577316_1	1168034.FH5T_00925	4.122e-159	514.0	COG1070@1|root,COG1070@2|Bacteria,4NIJC@976|Bacteroidetes,2FP4C@200643|Bacteroidia	976|Bacteroidetes	G	Carbohydrate kinase, FGGY family protein	rhaB	GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	2.7.1.5,2.7.1.51	ko:K00848,ko:K00879	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014,R03241	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
TLS3_k127_5577316_6	435590.BVU_1373	5.226e-33	127.0	COG2407@1|root,COG2407@2|Bacteria,4NHWI@976|Bacteroidetes,2FNPS@200643|Bacteroidia,4AK5W@815|Bacteroidaceae	976|Bacteroidetes	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	fucI	-	5.3.1.25,5.3.1.3	ko:K01818	ko00051,ko01120,map00051,map01120	-	R03163	RC00434	ko00000,ko00001,ko01000	-	-	-	Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2
TLS3_k127_5589502_0	869213.JCM21142_122	7.542e-178	569.0	COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes	976|Bacteroidetes	E	Xaa-His dipeptidase	pepD_2	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_5593955_2	1408473.JHXO01000004_gene130	8.793e-75	256.0	COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,2FNJV@200643|Bacteroidia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS3_k127_5593955_0	1168034.FH5T_15450	2.608e-117	383.0	COG0330@1|root,COG0330@2|Bacteria,4NEBV@976|Bacteroidetes,2FPV3@200643|Bacteroidia	976|Bacteroidetes	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TLS3_k127_5593955_5	742767.HMPREF9456_01722	1.116e-14	76.0	COG4877@1|root,COG4877@2|Bacteria,4NXSU@976|Bacteroidetes,2FUU4@200643|Bacteroidia,22YTT@171551|Porphyromonadaceae	976|Bacteroidetes	S	Arc-like DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
TLS3_k127_5593955_1	1408473.JHXO01000004_gene123	1.272e-75	260.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,2FKZG@200643|Bacteroidia	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
TLS3_k127_5593955_3	1408473.JHXO01000004_gene120	1.248e-63	222.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,2FSMW@200643|Bacteroidia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
TLS3_k127_5593955_4	926562.Oweho_3351	5.258e-19	92.0	28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,1I791@117743|Flavobacteriia,2PA5S@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5596204_4	856793.MICA_2035	2.582e-12	71.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,4BQ0Q@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	T	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657,ko:K07659,ko:K18144	ko01501,ko02020,ko02026,map01501,map02020,map02026	M00434,M00445,M00649,M00655,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_5596204_3	886379.AEWI01000003_gene586	1.361e-27	115.0	COG1993@1|root,COG1993@2|Bacteria,4NVRH@976|Bacteroidetes,2FV2T@200643|Bacteroidia,3XKWM@558415|Marinilabiliaceae	976|Bacteroidetes	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
TLS3_k127_5596204_2	385682.AFSL01000090_gene940	6.679e-33	132.0	COG0239@1|root,COG0239@2|Bacteria,4NV3N@976|Bacteroidetes,2FUP5@200643|Bacteroidia,3XKVT@558415|Marinilabiliaceae	976|Bacteroidetes	D	CrcB-like protein, Camphor Resistance (CrcB)	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
TLS3_k127_5596204_0	439235.Dalk_0293	4.126e-152	492.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
TLS3_k127_5596204_1	1047013.AQSP01000140_gene2494	2.574e-55	198.0	COG2234@1|root,COG2234@2|Bacteria,2NRCG@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
TLS3_k127_5599916_1	869213.JCM21142_104512	1.129e-70	243.0	COG4651@1|root,COG4651@2|Bacteria	2|Bacteria	P	solute:proton antiporter activity	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
TLS3_k127_5599916_6	1336803.PHEL49_1462	5.349e-07	59.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1I1B3@117743|Flavobacteriia,3VW6J@52959|Polaribacter	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
TLS3_k127_5599916_4	1123035.ARLA01000028_gene2312	2.509e-20	103.0	28I9R@1|root,2Z8CE@2|Bacteria,4NE54@976|Bacteroidetes,1HWWD@117743|Flavobacteriia,4C2R3@83612|Psychroflexus	976|Bacteroidetes	S	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
TLS3_k127_5599916_7	1268240.ATFI01000001_gene3645	3.746e-05	53.0	COG0823@1|root,COG0823@2|Bacteria,4PPE1@976|Bacteroidetes,2FP0G@200643|Bacteroidia,4ANRF@815|Bacteroidaceae	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
TLS3_k127_5599916_2	1408813.AYMG01000001_gene3499	1.11e-67	240.0	COG4198@1|root,COG4198@2|Bacteria,4NFUK@976|Bacteroidetes,1IPX6@117747|Sphingobacteriia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
TLS3_k127_5599916_3	746697.Aeqsu_0544	3.437e-42	162.0	COG4198@1|root,COG4198@2|Bacteria,4NFUK@976|Bacteroidetes,1HWZF@117743|Flavobacteriia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
TLS3_k127_5599916_0	1121007.AUML01000018_gene520	0.0	1117.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,1I86Y@117743|Flavobacteriia,2YIAA@290174|Aquimarina	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_5614041_2	929703.KE386491_gene201	3.251e-18	94.0	2EERZ@1|root,338JN@2|Bacteria,4NTN7@976|Bacteroidetes,47RB9@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,DUF4361
TLS3_k127_5614041_1	1185876.BN8_04072	1.285e-101	349.0	COG4198@1|root,COG4198@2|Bacteria,4NEQC@976|Bacteroidetes,47MYX@768503|Cytophagia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_2
TLS3_k127_5614041_0	1185876.BN8_04073	1.017e-292	930.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47M35@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_5614922_4	1121904.ARBP01000013_gene373	1.251e-43	178.0	COG2730@1|root,COG2730@2|Bacteria,4P1NI@976|Bacteroidetes,47TT8@768503|Cytophagia	976|Bacteroidetes	G	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
TLS3_k127_5614922_0	518766.Rmar_2521	4.751e-191	611.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1FKC5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
TLS3_k127_5614922_3	694427.Palpr_2028	6.762e-47	183.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,2FQ9F@200643|Bacteroidia,22WWB@171551|Porphyromonadaceae	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
TLS3_k127_5614922_6	1122605.KB893637_gene3326	8.874e-12	66.0	COG5297@1|root,COG5297@2|Bacteria,4PKPX@976|Bacteroidetes,1IV41@117747|Sphingobacteriia	976|Bacteroidetes	G	Fg-gap repeat	-	-	4.2.2.23	ko:K18197	-	-	-	-	ko00000,ko01000	-	PL11	-	-
TLS3_k127_5614922_5	1033732.CAHI01000007_gene2041	2.241e-38	154.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,2FM72@200643|Bacteroidia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_5614922_1	243090.RB12844	6.435e-103	342.0	COG3622@1|root,COG3622@2|Bacteria,2J4Z5@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_5614922_2	1168034.FH5T_06660	3.541e-95	316.0	COG1900@1|root,COG1900@2|Bacteria,4P06S@976|Bacteroidetes,2FWMQ@200643|Bacteroidia	976|Bacteroidetes	S	Homocysteine biosynthesis enzyme, sulfur-incorporation	-	-	-	-	-	-	-	-	-	-	-	-	HcyBio
TLS3_k127_5619192_4	1121912.AUHD01000019_gene3429	4.226e-38	150.0	COG1577@1|root,COG1577@2|Bacteria,4NEXC@976|Bacteroidetes,1HY6C@117743|Flavobacteriia	976|Bacteroidetes	I	GHMP Kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5619192_1	862908.BMS_1477	3.749e-125	414.0	COG1257@1|root,COG1257@2|Bacteria,1MXVE@1224|Proteobacteria,42R5Q@68525|delta/epsilon subdivisions,2MSVW@213481|Bdellovibrionales,2WN6K@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
TLS3_k127_5619192_2	1408473.JHXO01000008_gene2917	9.867e-112	370.0	COG1304@1|root,COG1304@2|Bacteria,4NJPE@976|Bacteroidetes,2FWAJ@200643|Bacteroidia	976|Bacteroidetes	C	COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid	-	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
TLS3_k127_5619192_0	1408473.JHXO01000008_gene2918	1.585e-148	479.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,2FR12@200643|Bacteroidia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_5619192_3	1122605.KB893645_gene1124	1.205e-40	160.0	COG1024@1|root,COG1024@2|Bacteria,4NI32@976|Bacteroidetes,1IT4Y@117747|Sphingobacteriia	976|Bacteroidetes	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
TLS3_k127_5619192_5	1408473.JHXO01000008_gene2921	3.651e-16	78.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,2FXCV@200643|Bacteroidia	976|Bacteroidetes	I	Carboxyl transferase domain	-	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
TLS3_k127_5629891_2	340177.Cag_0946	5.263e-246	769.0	COG4108@1|root,COG4108@2|Bacteria,1FEXE@1090|Chlorobi	1090|Chlorobi	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,RF3_C
TLS3_k127_5629891_0	1189612.A33Q_0644	0.0	1199.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,47NMT@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
TLS3_k127_5629891_8	293613.A1E_01360	5.402e-33	132.0	COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria	1224|Proteobacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
TLS3_k127_5629891_6	1408473.JHXO01000005_gene1571	6.424e-77	263.0	COG0177@1|root,COG0177@2|Bacteria,4NMJS@976|Bacteroidetes	976|Bacteroidetes	L	DNA lyase	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
TLS3_k127_5629891_5	1041826.FCOL_11550	1.296e-87	298.0	COG5383@1|root,COG5383@2|Bacteria,4NGFT@976|Bacteroidetes,1I068@117743|Flavobacteriia,2NSZC@237|Flavobacterium	976|Bacteroidetes	S	DUF1338	-	-	-	-	-	-	-	-	-	-	-	-	DUF1338
TLS3_k127_5629891_1	714943.Mucpa_6038	5.746e-319	987.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,1IQI9@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
TLS3_k127_5629891_3	694427.Palpr_2417	2.576e-219	687.0	COG1260@1|root,COG1260@2|Bacteria,4NI0F@976|Bacteroidetes,2FMB3@200643|Bacteroidia,22WM9@171551|Porphyromonadaceae	976|Bacteroidetes	I	Myo-inositol-1-phosphate synthase	ino1	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
TLS3_k127_5629891_7	316274.Haur_3400	7.157e-50	184.0	COG0406@1|root,COG0406@2|Bacteria,2G73Q@200795|Chloroflexi,37737@32061|Chloroflexia	32061|Chloroflexia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
TLS3_k127_5629891_4	1237149.C900_05435	1.132e-195	626.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,47JQI@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS3_k127_5629985_2	243160.BMAA0765	4.365e-11	66.0	COG1063@1|root,COG1063@2|Bacteria,1MWX0@1224|Proteobacteria,2VM0W@28216|Betaproteobacteria,1KFG1@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.380	ko:K08322	ko00040,ko01100,map00040,map01100	-	R10848	RC00085	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_5629985_0	935837.JAEK01000008_gene3348	4.442e-103	342.0	COG3618@1|root,COG3618@2|Bacteria,1URZE@1239|Firmicutes,4HAYX@91061|Bacilli,1ZG0M@1386|Bacillus	91061|Bacilli	S	Amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
TLS3_k127_5629985_1	335543.Sfum_2347	6.413e-71	245.0	COG0438@1|root,COG0438@2|Bacteria,1RA8H@1224|Proteobacteria,42RMM@68525|delta/epsilon subdivisions,2WNQY@28221|Deltaproteobacteria,2MQWR@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5640814_5	694427.Palpr_1812	8.88e-79	270.0	COG2942@1|root,COG2942@2|Bacteria,4NEH7@976|Bacteroidetes,2FM9N@200643|Bacteroidia,22X27@171551|Porphyromonadaceae	976|Bacteroidetes	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	bfce	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
TLS3_k127_5640814_0	742767.HMPREF9456_01860	2.319e-164	524.0	COG1488@1|root,COG1488@2|Bacteria,4NFQK@976|Bacteroidetes,2FM8S@200643|Bacteroidia,22XJW@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
TLS3_k127_5640814_4	313606.M23134_03473	6.844e-84	286.0	COG1335@1|root,COG1335@2|Bacteria,4NKYM@976|Bacteroidetes,47MBU@768503|Cytophagia	976|Bacteroidetes	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
TLS3_k127_5640814_2	385682.AFSL01000035_gene2912	9.09e-115	385.0	COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,2FN7G@200643|Bacteroidia,3XJY9@558415|Marinilabiliaceae	976|Bacteroidetes	E	Papain family cysteine protease	pepC	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1,Peptidase_C1_2
TLS3_k127_5640814_3	616991.JPOO01000001_gene3704	1.394e-89	321.0	28IRY@1|root,2Z8R6@2|Bacteria,4NIMI@976|Bacteroidetes	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_5640814_1	1267535.KB906767_gene4768	2.491e-117	404.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5640814_6	1380384.JADN01000004_gene2029	1.958e-68	239.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HX1V@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
TLS3_k127_5641185_0	679937.Bcop_1219	3.675e-154	497.0	COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,2FPM1@200643|Bacteroidia,4AMBA@815|Bacteroidaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
TLS3_k127_5641185_1	525897.Dbac_1773	7.817e-42	158.0	COG0454@1|root,COG0456@2|Bacteria,1MYK6@1224|Proteobacteria,42TT3@68525|delta/epsilon subdivisions,2WQGD@28221|Deltaproteobacteria,2MCMQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
TLS3_k127_5661298_2	1123009.AUID01000008_gene840	5.765e-08	59.0	2E5UQ@1|root,330IY@2|Bacteria,1VI50@1239|Firmicutes,24QVH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5661298_0	1123008.KB905715_gene3639	2.97e-217	683.0	COG0502@1|root,COG0502@2|Bacteria,4NEI7@976|Bacteroidetes,2FM8N@200643|Bacteroidia,22VVB@171551|Porphyromonadaceae	976|Bacteroidetes	C	In Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and IscS	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
TLS3_k127_5661298_1	1348583.ATLH01000029_gene1480	1.396e-21	102.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,1HXQ5@117743|Flavobacteriia,1F8E3@104264|Cellulophaga	976|Bacteroidetes	H	Riboflavin kinase	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
TLS3_k127_5666374_3	313598.MED152_12639	2.513e-27	116.0	COG2335@1|root,COG2335@2|Bacteria,4NH49@976|Bacteroidetes,1HXZS@117743|Flavobacteriia,3VXGZ@52959|Polaribacter	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
TLS3_k127_5666374_2	1168034.FH5T_10530	3.25e-55	197.0	COG2335@1|root,COG2335@2|Bacteria,4NGU3@976|Bacteroidetes,2FQ02@200643|Bacteroidia	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	ko:K19519	-	-	-	-	ko00000,ko04516	-	-	-	DUF5108,Fasciclin
TLS3_k127_5666374_1	1239962.C943_03495	1.057e-61	224.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,4NERC@976|Bacteroidetes,47K07@768503|Cytophagia	976|Bacteroidetes	K	PFAM MerR family regulatory protein	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
TLS3_k127_5666374_0	1191523.MROS_2744	2.408e-206	653.0	COG4799@1|root,COG4799@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01966,ko:K01969	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00036,M00373,M00741	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
TLS3_k127_5667245_2	694427.Palpr_1550	4.125e-95	320.0	COG0809@1|root,COG0809@2|Bacteria,4NDZ5@976|Bacteroidetes,2FNJD@200643|Bacteroidia,22X1R@171551|Porphyromonadaceae	976|Bacteroidetes	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
TLS3_k127_5667245_5	929556.Solca_3742	4.064e-78	273.0	COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes,1IRT8@117747|Sphingobacteriia	976|Bacteroidetes	P	ABC-type phosphate transport system periplasmic	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
TLS3_k127_5667245_6	153721.MYP_4029	4.281e-48	196.0	COG0457@1|root,COG0457@2|Bacteria,4NIEU@976|Bacteroidetes,47XPU@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
TLS3_k127_5667245_12	1121957.ATVL01000007_gene2410	4.587e-05	57.0	COG1629@1|root,COG1629@2|Bacteria,4NH4T@976|Bacteroidetes,47KSU@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_5667245_4	153721.MYP_4035	2.198e-85	291.0	COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,47MMA@768503|Cytophagia	976|Bacteroidetes	U	MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
TLS3_k127_5667245_9	1235803.C825_01043	1.276e-34	140.0	COG0848@1|root,COG0848@2|Bacteria,4NMT4@976|Bacteroidetes,2FQHV@200643|Bacteroidia,22XSU@171551|Porphyromonadaceae	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	exbD1	-	-	-	-	-	-	-	-	-	-	-	ExbD
TLS3_k127_5667245_8	1121129.KB903359_gene1129	8.198e-37	147.0	COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,2FM45@200643|Bacteroidia,22XUA@171551|Porphyromonadaceae	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	exbD2	-	-	-	-	-	-	-	-	-	-	-	ExbD
TLS3_k127_5667245_7	1227739.Hsw_0355	3.248e-39	156.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,47XHA@768503|Cytophagia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_5667245_1	1168034.FH5T_16690	5.177e-132	430.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,2FPGW@200643|Bacteroidia	976|Bacteroidetes	E	Threonine aldolase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
TLS3_k127_5667245_11	401053.AciPR4_1493	4.666e-08	56.0	2C74X@1|root,3304C@2|Bacteria,3Y5TB@57723|Acidobacteria,2JK6Z@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5667245_0	1340493.JNIF01000004_gene829	1.18e-207	660.0	COG0591@1|root,COG0591@2|Bacteria,3Y42K@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
TLS3_k127_5667245_3	1168034.FH5T_13710	6.966e-89	300.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,2FP2H@200643|Bacteroidia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
TLS3_k127_5667245_10	468059.AUHA01000002_gene556	3.376e-17	81.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,1IPMJ@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Shikimate dehydrogenase substrate binding	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
TLS3_k127_5678784_3	1408473.JHXO01000004_gene213	5.094e-149	477.0	COG0065@1|root,COG0065@2|Bacteria,4NG7E@976|Bacteroidetes,2FMCX@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
TLS3_k127_5678784_6	926556.Echvi_2060	2.904e-78	266.0	COG0066@1|root,COG0066@2|Bacteria,4NDVY@976|Bacteroidetes,47NNG@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
TLS3_k127_5678784_0	886379.AEWI01000023_gene35	4.082e-225	707.0	COG0119@1|root,COG0119@2|Bacteria,4NF3N@976|Bacteroidetes,2FKYJ@200643|Bacteroidia,3XJ9C@558415|Marinilabiliaceae	976|Bacteroidetes	E	LeuA allosteric (dimerisation) domain	leuA_1	-	2.3.1.182	ko:K09011	ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230	M00535	R07399	RC00004,RC01205	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
TLS3_k127_5678784_1	289376.THEYE_A0114	1.763e-177	561.0	COG0473@1|root,COG0473@2|Bacteria,3J0JQ@40117|Nitrospirae	40117|Nitrospirae	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
TLS3_k127_5678784_5	421072.IO89_12285	2.97e-121	394.0	COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,1HWP3@117743|Flavobacteriia,3HH2P@358033|Chryseobacterium	976|Bacteroidetes	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
TLS3_k127_5678784_2	1121897.AUGO01000005_gene73	3.537e-157	506.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1HZ69@117743|Flavobacteriia,2NSJG@237|Flavobacterium	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
TLS3_k127_5678784_4	1216967.L100_04007	1.858e-126	413.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes,1HYNA@117743|Flavobacteriia,34PJV@308865|Elizabethkingia	976|Bacteroidetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9,4.1.1.81	ko:K00817,ko:K04720	ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243,R06530	RC00006,RC00517,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_5684558_2	1174528.JH992898_gene4534	1.554e-27	123.0	COG0745@1|root,COG5000@1|root,COG0745@2|Bacteria,COG5000@2|Bacteria,1GPZW@1117|Cyanobacteria,1JI0S@1189|Stigonemataceae	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
TLS3_k127_5684558_1	28072.Nos7524_3038	2.28e-57	203.0	COG0745@1|root,COG0745@2|Bacteria,1G51F@1117|Cyanobacteria,1HN3A@1161|Nostocales	1117|Cyanobacteria	T	PFAM response regulator receiver	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
TLS3_k127_5684558_0	926549.KI421517_gene1328	1.537e-70	245.0	COG0745@1|root,COG0745@2|Bacteria,4NE77@976|Bacteroidetes,47K3Z@768503|Cytophagia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_5684558_4	714943.Mucpa_0788	1.136e-06	53.0	COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes	976|Bacteroidetes	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_5684558_3	1492737.FEM08_20940	5.384e-25	120.0	COG1345@1|root,COG1520@1|root,COG2356@1|root,COG3291@1|root,COG1345@2|Bacteria,COG1520@2|Bacteria,COG2356@2|Bacteria,COG3291@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,2NSFX@237|Flavobacterium	976|Bacteroidetes	N	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_5686737_2	1121129.KB903359_gene2298	2.737e-26	119.0	COG0810@1|root,COG0810@2|Bacteria,4NWAV@976|Bacteroidetes,2G2AV@200643|Bacteroidia,22Z11@171551|Porphyromonadaceae	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
TLS3_k127_5686737_3	755732.Fluta_0942	1.431e-21	103.0	2BBSK@1|root,32XPV@2|Bacteria,4NSW3@976|Bacteroidetes,1IKDA@117743|Flavobacteriia,2PB42@246874|Cryomorphaceae	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_5686737_0	945713.IALB_2768	4.36e-218	688.0	COG4231@1|root,COG4231@2|Bacteria	2|Bacteria	C	indolepyruvate ferredoxin oxidoreductase activity	iorA	-	1.2.7.8	ko:K00179,ko:K08941	-	M00598	-	-	br01601,ko00000,ko00002,ko00194,ko01000	-	-	-	POR_N,TPP_enzyme_C
TLS3_k127_5686737_1	1349822.NSB1T_10975	1.653e-76	261.0	COG1014@1|root,COG1014@2|Bacteria,4NGN3@976|Bacteroidetes,2FP78@200643|Bacteroidia,22X20@171551|Porphyromonadaceae	976|Bacteroidetes	C	Indolepyruvate	iorB	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
TLS3_k127_5699171_0	1122931.AUAE01000007_gene1312	3.979e-147	472.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,2FM3B@200643|Bacteroidia,22VY6@171551|Porphyromonadaceae	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bepE_4	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
TLS3_k127_5699171_1	585543.HMPREF0969_01084	2.494e-107	363.0	COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,2FMRJ@200643|Bacteroidia,4AME3@815|Bacteroidaceae	976|Bacteroidetes	MU	Psort location OuterMembrane, score	tolC	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_5699171_2	886379.AEWI01000009_gene715	2.994e-86	295.0	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,2FM75@200643|Bacteroidia,3XJPM@558415|Marinilabiliaceae	976|Bacteroidetes	F	Phosphorylase superfamily	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
TLS3_k127_5708973_1	945713.IALB_1057	6.282e-106	365.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	3.4.17.22	ko:K06987,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CarboxypepD_reg,PKD,Peptidase_M14
TLS3_k127_5708973_0	509635.N824_04710	1.124e-133	435.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
TLS3_k127_5713838_1	742726.HMPREF9448_02737	1.058e-155	500.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes,2FNB7@200643|Bacteroidia,22X71@171551|Porphyromonadaceae	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
TLS3_k127_5713838_2	929562.Emtol_0789	8.432e-102	339.0	COG0524@1|root,COG0524@2|Bacteria,4NENQ@976|Bacteroidetes,47MN5@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
TLS3_k127_5713838_0	1168034.FH5T_07000	1.407e-178	571.0	COG3408@1|root,COG3408@2|Bacteria,4NESP@976|Bacteroidetes,2FMGH@200643|Bacteroidia	976|Bacteroidetes	G	Alpha-L-rhamnosidase N-terminal domain protein	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
TLS3_k127_5719688_1	616991.JPOO01000001_gene3038	1.751e-93	316.0	COG3540@1|root,COG3540@2|Bacteria,4NFXQ@976|Bacteroidetes,1HY2S@117743|Flavobacteriia,23I26@178469|Arenibacter	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
TLS3_k127_5719688_0	1121904.ARBP01000029_gene2171	1.594e-162	526.0	COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,47TVZ@768503|Cytophagia	976|Bacteroidetes	P	Protein of unknown function (DUF229)	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TLS3_k127_5719688_2	471854.Dfer_2208	2.353e-32	132.0	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,47T93@768503|Cytophagia	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_572932_5	925409.KI911562_gene1591	3.455e-85	289.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IRBB@117747|Sphingobacteriia	976|Bacteroidetes	I	SPTR Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
TLS3_k127_572932_0	925409.KI911562_gene1590	0.0	1485.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IP40@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
TLS3_k127_572932_4	927658.AJUM01000034_gene184	1.265e-119	415.0	COG3291@1|root,COG3291@2|Bacteria,4PHVT@976|Bacteroidetes,2FUHU@200643|Bacteroidia,3XIYY@558415|Marinilabiliaceae	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_572932_2	1121904.ARBP01000003_gene6463	6.893e-135	440.0	COG0460@1|root,COG0460@2|Bacteria,4NHRC@976|Bacteroidetes,47KVU@768503|Cytophagia	976|Bacteroidetes	E	Homoserine dehydrogenase, NAD binding domain	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
TLS3_k127_572932_3	926549.KI421517_gene1840	1.644e-122	403.0	COG2021@1|root,COG2021@2|Bacteria,4NFG2@976|Bacteroidetes,47KMZ@768503|Cytophagia	976|Bacteroidetes	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
TLS3_k127_572932_1	1168034.FH5T_19740	1.972e-196	620.0	COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,2FMQX@200643|Bacteroidia	976|Bacteroidetes	E	O-acetylhomoserine aminocarboxypropyltransferase cysteine synthase	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
TLS3_k127_572932_7	700598.Niako_4151	6.149e-12	73.0	2A3Y3@1|root,30SGF@2|Bacteria,4NZA3@976|Bacteroidetes,1IZPV@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_572932_6	485916.Dtox_3783	3.285e-75	267.0	COG0642@1|root,COG0642@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,267E6@186807|Peptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638,HATPase_c,HisKA,Hpt,Response_reg
TLS3_k127_5738283_0	1121904.ARBP01000005_gene4767	1.268e-128	417.0	COG1082@1|root,COG1082@2|Bacteria,4NG75@976|Bacteroidetes,47JT2@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
TLS3_k127_5738283_1	1168034.FH5T_12325	1.085e-96	330.0	COG0642@1|root,COG2205@2|Bacteria	1168034.FH5T_12325|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5738283_2	1408473.JHXO01000013_gene618	3.313e-85	286.0	COG1288@1|root,COG1288@2|Bacteria,4NEUI@976|Bacteroidetes,2FQKK@200643|Bacteroidia	976|Bacteroidetes	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
TLS3_k127_5759032_4	470145.BACCOP_03622	9.831e-93	308.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,2FP0X@200643|Bacteroidia,4AKCI@815|Bacteroidaceae	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
TLS3_k127_5759032_2	742817.HMPREF9449_01738	7.5e-177	563.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,2FMC3@200643|Bacteroidia,22WEF@171551|Porphyromonadaceae	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
TLS3_k127_5759032_1	1408473.JHXO01000001_gene2460	5.697e-182	581.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,2FM8E@200643|Bacteroidia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_5759032_0	869213.JCM21142_31289	3.61e-199	642.0	COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,47K6U@768503|Cytophagia	976|Bacteroidetes	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
TLS3_k127_5759032_3	693979.Bache_0476	5.135e-105	348.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,2FMPT@200643|Bacteroidia,4AM5W@815|Bacteroidaceae	976|Bacteroidetes	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
TLS3_k127_5759032_5	927658.AJUM01000040_gene919	9.552e-36	138.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,2FUA3@200643|Bacteroidia,3XK4Z@558415|Marinilabiliaceae	976|Bacteroidetes	K	MraZ protein, putative antitoxin-like	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
TLS3_k127_5768036_1	1519464.HY22_01480	6.069e-162	524.0	COG0841@1|root,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS3_k127_5768036_0	1433126.BN938_0794	3.369e-223	703.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,2FPXP@200643|Bacteroidia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
TLS3_k127_5778862_1	435591.BDI_1827	5.049e-128	411.0	COG2133@1|root,COG2133@2|Bacteria,4PKJE@976|Bacteroidetes,2FX58@200643|Bacteroidia,231GZ@171551|Porphyromonadaceae	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_5778862_0	1279009.ADICEAN_03440	3.861e-159	508.0	COG2152@1|root,COG2152@2|Bacteria,4NG7B@976|Bacteroidetes,47MHY@768503|Cytophagia	976|Bacteroidetes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	3.2.1.197	ko:K21065	-	-	R11544	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
TLS3_k127_5778862_2	1408473.JHXO01000006_gene1263	1.1e-121	396.0	COG0788@1|root,COG0788@2|Bacteria,4NEGJ@976|Bacteroidetes,2FN3H@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
TLS3_k127_5791282_2	1123508.JH636442_gene4178	5.205e-28	117.0	COG1520@1|root,COG1520@2|Bacteria,2IXXG@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
TLS3_k127_5791282_1	1121373.KB903632_gene485	1.273e-35	140.0	COG1278@1|root,COG1278@2|Bacteria,4NNNH@976|Bacteroidetes,47QKE@768503|Cytophagia	976|Bacteroidetes	K	Cold shock protein domain	cspG	-	-	-	-	-	-	-	-	-	-	-	CSD
TLS3_k127_5791282_0	694430.Natoc_2617	4.324e-41	171.0	arCOG02348@1|root,arCOG02350@1|root,arCOG07605@1|root,arCOG02348@2157|Archaea,arCOG02350@2157|Archaea,arCOG07605@2157|Archaea,2Y7VS@28890|Euryarchaeota,2410W@183963|Halobacteria	183963|Halobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
TLS3_k127_5791282_3	1380354.JIAN01000007_gene76	1.994e-07	64.0	COG4251@1|root,COG5278@1|root,COG4251@2|Bacteria,COG5278@2|Bacteria,2GK25@201174|Actinobacteria,4F0F2@85016|Cellulomonadaceae	201174|Actinobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA
TLS3_k127_580749_11	469595.CSAG_00401	1.596e-09	60.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RMVE@1236|Gammaproteobacteria,3WZFE@544|Citrobacter	1236|Gammaproteobacteria	C	TAT (twin-arginine translocation) pathway signal sequence	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
TLS3_k127_580749_7	886379.AEWI01000062_gene2293	2.989e-53	197.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia,3XIRK@558415|Marinilabiliaceae	976|Bacteroidetes	S	Bacterial SH3 domain	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
TLS3_k127_580749_1	1408473.JHXO01000004_gene61	5.326e-139	462.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,2FMK5@200643|Bacteroidia	976|Bacteroidetes	T	Tetratricopeptide repeat protein	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
TLS3_k127_580749_10	742817.HMPREF9449_01244	4.553e-32	135.0	COG1729@1|root,COG1729@2|Bacteria,4PNIR@976|Bacteroidetes,2G0Y9@200643|Bacteroidia,2325N@171551|Porphyromonadaceae	976|Bacteroidetes	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_16,TPR_2
TLS3_k127_580749_4	1168034.FH5T_13670	2.573e-115	381.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,2FN4B@200643|Bacteroidia	976|Bacteroidetes	S	Von Willebrand factor type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
TLS3_k127_580749_2	1408473.JHXO01000004_gene64	8.105e-132	428.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,2FNXM@200643|Bacteroidia	976|Bacteroidetes	S	Von Willebrand factor type A domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
TLS3_k127_580749_8	1408473.JHXO01000004_gene65	9.074e-51	192.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,2FP8Y@200643|Bacteroidia	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_580749_3	1168289.AJKI01000029_gene1439	5.911e-128	414.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,2FNSY@200643|Bacteroidia,3XIXB@558415|Marinilabiliaceae	976|Bacteroidetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TLS3_k127_580749_0	1121129.KB903359_gene1252	5.342e-165	523.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,2FMGP@200643|Bacteroidia,22W2U@171551|Porphyromonadaceae	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TLS3_k127_580749_6	926549.KI421517_gene1122	8.145e-66	241.0	28I3N@1|root,2Z87C@2|Bacteria,4NE8P@976|Bacteroidetes,47M50@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
TLS3_k127_580749_5	1168034.FH5T_19355	3.413e-78	269.0	COG1387@1|root,COG1387@2|Bacteria,4NMBC@976|Bacteroidetes,2FNU7@200643|Bacteroidia	976|Bacteroidetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_580749_9	545695.TREAZ_2398	6.67e-34	133.0	COG1994@1|root,COG1994@2|Bacteria,2J7KI@203691|Spirochaetes	203691|Spirochaetes	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
TLS3_k127_5808546_1	1144313.PMI10_04124	8.57e-74	265.0	COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,1HYKS@117743|Flavobacteriia,2NSAV@237|Flavobacterium	976|Bacteroidetes	E	Transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
TLS3_k127_5808546_0	1237149.C900_04627	3.989e-120	408.0	COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,47JVH@768503|Cytophagia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
TLS3_k127_5808546_3	1210884.HG799462_gene8853	1.551e-07	58.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TLS3_k127_5846442_2	470145.BACCOP_01433	1.829e-35	147.0	COG3203@1|root,COG3203@2|Bacteria,4NMHJ@976|Bacteroidetes,2FT17@200643|Bacteroidia,4AQY3@815|Bacteroidaceae	976|Bacteroidetes	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5846442_1	1121904.ARBP01000001_gene5400	7.011e-91	308.0	COG1082@1|root,COG1082@2|Bacteria,4NKFY@976|Bacteroidetes,47N9K@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,DUF1080
TLS3_k127_5846442_0	1122931.AUAE01000007_gene1342	6.748e-178	577.0	COG0457@1|root,COG0457@2|Bacteria,4NKMF@976|Bacteroidetes,2FXC5@200643|Bacteroidia,231HD@171551|Porphyromonadaceae	1122931.AUAE01000007_gene1342|-	S	Domain of unknown function (DUF5107)	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5859658_2	153721.MYP_188	1.656e-75	256.0	COG1541@1|root,COG1541@2|Bacteria,4NGRR@976|Bacteroidetes,47MXQ@768503|Cytophagia	976|Bacteroidetes	H	AMP-binding enzyme	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
TLS3_k127_5859658_5	153721.MYP_190	1.053e-29	126.0	2E7GE@1|root,331Z7@2|Bacteria,4NWN3@976|Bacteroidetes,47RY7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5859658_4	357276.EL88_24230	4.301e-45	167.0	COG0824@1|root,COG0824@2|Bacteria,4NRHH@976|Bacteroidetes,2FTJB@200643|Bacteroidia,4AQGM@815|Bacteroidaceae	976|Bacteroidetes	S	acyl-CoA thioester hydrolase, YbgC YbaW family	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
TLS3_k127_5859658_1	153721.MYP_4262	1.277e-101	342.0	COG0304@1|root,COG0304@2|Bacteria,4NE8K@976|Bacteroidetes,47PEB@768503|Cytophagia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, C-terminal domain	fabF2	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_5859658_3	1341155.FSS13T_06140	5.427e-51	192.0	COG0304@1|root,COG0304@2|Bacteria,4NMSI@976|Bacteroidetes,1I1RZ@117743|Flavobacteriia,2NU0R@237|Flavobacterium	976|Bacteroidetes	IQ	3-oxoacyl-ACP synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5859658_6	1517682.HW49_07580	1.384e-24	105.0	COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes,2FTE9@200643|Bacteroidia,22YSF@171551|Porphyromonadaceae	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TLS3_k127_5859658_0	153721.MYP_4265	1.033e-116	384.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,47N4W@768503|Cytophagia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_5861249_10	1218108.KB908297_gene2909	2.091e-18	85.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,1HYNK@117743|Flavobacteriia	976|Bacteroidetes	S	stress-induced protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
TLS3_k127_5861249_2	927658.AJUM01000044_gene663	2.644e-155	503.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,2G334@200643|Bacteroidia,3XJEA@558415|Marinilabiliaceae	976|Bacteroidetes	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
TLS3_k127_5861249_1	869213.JCM21142_83238	6.556e-206	649.0	COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,47KN6@768503|Cytophagia	976|Bacteroidetes	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
TLS3_k127_5861249_9	1408473.JHXO01000006_gene1355	1.224e-38	165.0	COG3137@1|root,COG3137@2|Bacteria,4NRXD@976|Bacteroidetes,2FNZ5@200643|Bacteroidia	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
TLS3_k127_5861249_3	929703.KE386491_gene248	1.117e-115	384.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,47M7W@768503|Cytophagia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5861249_6	929556.Solca_0551	9.479e-98	328.0	COG0382@1|root,COG0382@2|Bacteria,4NEE3@976|Bacteroidetes,1IP3B@117747|Sphingobacteriia	976|Bacteroidetes	H	4-hydroxybenzoate polyprenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
TLS3_k127_5861249_0	709991.Odosp_0841	7.523e-295	927.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,2FNBF@200643|Bacteroidia,22WG1@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
TLS3_k127_5861249_7	1408473.JHXO01000011_gene3060	5.363e-89	301.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,2FMRR@200643|Bacteroidia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
TLS3_k127_5861249_11	1408473.JHXO01000011_gene3061	5.297e-09	62.0	2905P@1|root,2ZMVJ@2|Bacteria,4P7JK@976|Bacteroidetes,2G040@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5861249_4	742817.HMPREF9449_02920	8.424e-115	385.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,2FPE5@200643|Bacteroidia,22WGC@171551|Porphyromonadaceae	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
TLS3_k127_5861249_8	926562.Oweho_1586	7.485e-79	270.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,1HX1M@117743|Flavobacteriia,2PAR7@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
TLS3_k127_5861249_5	1168289.AJKI01000012_gene257	6.877e-109	370.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,2FQ8Z@200643|Bacteroidia,3XJ3Q@558415|Marinilabiliaceae	976|Bacteroidetes	N	ABC-type uncharacterized transport system	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
TLS3_k127_5872667_2	1123008.KB905693_gene1480	6.077e-57	201.0	COG4975@1|root,COG4975@2|Bacteria,4NF22@976|Bacteroidetes,2FMYN@200643|Bacteroidia,22X3I@171551|Porphyromonadaceae	976|Bacteroidetes	G	Sugar transport protein	-	-	-	ko:K05340	-	-	-	-	ko00000,ko02000	2.A.7.5	-	-	Ureide_permease
TLS3_k127_5872667_1	1121904.ARBP01000013_gene371	1.143e-115	396.0	2CB42@1|root,2Z7Y3@2|Bacteria,4NEUY@976|Bacteroidetes,47N6R@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5872667_0	1288963.ADIS_4246	3.261e-157	511.0	COG3420@1|root,COG3420@2|Bacteria,4NF5Y@976|Bacteroidetes,47YCA@768503|Cytophagia	976|Bacteroidetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TLS3_k127_5920787_4	526222.Desal_2417	4.863e-41	155.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,42PIX@68525|delta/epsilon subdivisions,2WJRF@28221|Deltaproteobacteria,2MA0J@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	cysT	-	-	ko:K02018,ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00189,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5,3.A.1.8	-	-	BPD_transp_1
TLS3_k127_5920787_1	403833.Pmob_0377	3.594e-69	249.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	-	-	3.6.3.29,3.6.3.55	ko:K02017,ko:K15497	ko02010,map02010	M00189,M00423	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.5,3.A.1.8	-	-	ABC_tran,TOBE
TLS3_k127_5920787_2	926569.ANT_16690	1.601e-61	227.0	COG0303@1|root,COG0303@2|Bacteria,2G667@200795|Chloroflexi	200795|Chloroflexi	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
TLS3_k127_5920787_0	1408473.JHXO01000010_gene3617	4.765e-101	335.0	COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,2FVWA@200643|Bacteroidia	976|Bacteroidetes	H	4Fe-4S single cluster domain	moaA	-	4.1.99.22,4.6.1.17	ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
TLS3_k127_5920787_3	1408473.JHXO01000010_gene3616	5.425e-47	173.0	COG0315@1|root,COG0315@2|Bacteria,4NHA0@976|Bacteroidetes	976|Bacteroidetes	H	Molybdenum cofactor biosynthesis protein	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
TLS3_k127_5921401_3	1122931.AUAE01000007_gene1253	6.146e-137	437.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,2FMM2@200643|Bacteroidia,22WCA@171551|Porphyromonadaceae	976|Bacteroidetes	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
TLS3_k127_5921401_0	886379.AEWI01000012_gene1072	6.336e-219	691.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,2FNMT@200643|Bacteroidia,3XIJE@558415|Marinilabiliaceae	976|Bacteroidetes	H	Fumarate reductase flavoprotein C-term	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
TLS3_k127_5921401_5	1168034.FH5T_15035	2.977e-66	238.0	COG1266@1|root,COG1266@2|Bacteria,4NFKV@976|Bacteroidetes,2FS4V@200643|Bacteroidia	976|Bacteroidetes	S	CAAX protease self-immunity	yyaK	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
TLS3_k127_5921401_2	742725.HMPREF9450_00320	2.857e-150	481.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,2FM9Z@200643|Bacteroidia,22U6Z@171550|Rikenellaceae	976|Bacteroidetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
TLS3_k127_5921401_6	1168289.AJKI01000002_gene2607	2.914e-60	216.0	28NZ3@1|root,2ZBW2@2|Bacteria,4NNDG@976|Bacteroidetes,2G2K7@200643|Bacteroidia,3XJIT@558415|Marinilabiliaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5921401_7	927658.AJUM01000042_gene1640	5.697e-46	172.0	COG4309@1|root,COG4309@2|Bacteria,4NQP0@976|Bacteroidetes,2FUI1@200643|Bacteroidia,3XKFI@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1858)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,DUF2249
TLS3_k127_5921401_1	927658.AJUM01000042_gene1639	3.677e-169	540.0	COG2461@1|root,COG2461@2|Bacteria,4NJQA@976|Bacteroidetes,2FMK7@200643|Bacteroidia,3XKFV@558415|Marinilabiliaceae	976|Bacteroidetes	S	PAS domain	-	-	-	ko:K09155	-	-	-	-	ko00000	-	-	-	DUF1858,DUF438,Hemerythrin,PAS_10
TLS3_k127_5921401_4	1122931.AUAE01000003_gene303	5.122e-95	321.0	COG0348@1|root,COG0348@2|Bacteria,4NN2H@976|Bacteroidetes,2FSAA@200643|Bacteroidia,22XSN@171551|Porphyromonadaceae	976|Bacteroidetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
TLS3_k127_5921401_8	385682.AFSL01000014_gene2774	4.858e-38	148.0	COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,2FYF3@200643|Bacteroidia,3XKA4@558415|Marinilabiliaceae	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
TLS3_k127_5927932_3	1408473.JHXO01000013_gene532	5.274e-120	389.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,2FM2X@200643|Bacteroidia	976|Bacteroidetes	H	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
TLS3_k127_5927932_4	1185876.BN8_02095	2.134e-94	314.0	COG0175@1|root,COG0175@2|Bacteria,4NGVI@976|Bacteroidetes,47KPR@768503|Cytophagia	976|Bacteroidetes	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
TLS3_k127_5927932_7	866536.Belba_0697	1.579e-20	95.0	COG3205@1|root,COG3205@2|Bacteria,4NV6E@976|Bacteroidetes,47SXF@768503|Cytophagia	976|Bacteroidetes	S	Predicted membrane protein (DUF2061)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2061
TLS3_k127_5927932_9	490899.DKAM_1057	1.373e-05	56.0	COG1418@1|root,arCOG01860@2157|Archaea,2XQDI@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
TLS3_k127_5927932_6	1168289.AJKI01000003_gene2794	6.708e-32	126.0	2CZWI@1|root,32T79@2|Bacteria,4NSNW@976|Bacteroidetes,2FTY4@200643|Bacteroidia,3XK8B@558415|Marinilabiliaceae	976|Bacteroidetes	S	COG NOG19094 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5927932_5	1408473.JHXO01000011_gene3070	3.256e-63	228.0	COG1427@1|root,COG1427@2|Bacteria,4NN4W@976|Bacteroidetes,2FXYF@200643|Bacteroidia	976|Bacteroidetes	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
TLS3_k127_5927932_1	1250005.PHEL85_0758	1.342e-203	641.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,1HXVA@117743|Flavobacteriia,3VW9H@52959|Polaribacter	976|Bacteroidetes	F	Adenylosuccinate lyase C-terminal	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
TLS3_k127_5927932_2	742817.HMPREF9449_01099	9.676e-186	598.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,2FMUK@200643|Bacteroidia,22VY0@171551|Porphyromonadaceae	976|Bacteroidetes	V	ABC transporter, ATP-binding protein	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS3_k127_5927932_0	485918.Cpin_5411	3.368e-275	857.0	COG1874@1|root,COG1874@2|Bacteria,4P1ST@976|Bacteroidetes	976|Bacteroidetes	G	Glycosyl hydrolases family 35	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_35
TLS3_k127_5927932_8	886379.AEWI01000001_gene1816	3.686e-06	51.0	COG4225@1|root,COG4225@2|Bacteria,4NFWI@976|Bacteroidetes,2FWNU@200643|Bacteroidia,3XJ28@558415|Marinilabiliaceae	976|Bacteroidetes	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
TLS3_k127_5929685_7	665571.STHERM_c02580	0.0007563	44.0	COG2222@1|root,COG2222@2|Bacteria	2|Bacteria	M	isomerase activity	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
TLS3_k127_5929685_4	1123508.JH636449_gene7331	3.514e-36	148.0	COG2120@1|root,COG2120@2|Bacteria,2IYPC@203682|Planctomycetes	203682|Planctomycetes	S	LmbE homologs	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TLS3_k127_5929685_2	742727.HMPREF9447_02191	1.11e-58	211.0	COG2199@1|root,COG3706@2|Bacteria,4NPU1@976|Bacteroidetes,2FNEU@200643|Bacteroidia,4AM1T@815|Bacteroidaceae	976|Bacteroidetes	T	Carbohydrate-binding family 9	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_2
TLS3_k127_5929685_0	709991.Odosp_3208	6.172e-86	307.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,2FNAC@200643|Bacteroidia,22WR4@171551|Porphyromonadaceae	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,fn3_3
TLS3_k127_5929685_6	760192.Halhy_3044	3.713e-14	81.0	COG1266@1|root,COG1266@2|Bacteria,4P5RH@976|Bacteroidetes	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
TLS3_k127_5929685_1	1313301.AUGC01000003_gene2121	1.453e-76	267.0	COG0451@1|root,COG0451@2|Bacteria,4NEMN@976|Bacteroidetes	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
TLS3_k127_5929685_3	313606.M23134_04251	1.123e-48	184.0	COG0300@1|root,COG0300@2|Bacteria,4NKNE@976|Bacteroidetes,47PBG@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
TLS3_k127_5929685_5	929556.Solca_1339	1.347e-30	126.0	COG0682@1|root,COG0682@2|Bacteria,4NFP7@976|Bacteroidetes,1IQYZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
TLS3_k127_5932159_7	391598.FBBAL38_06105	5.37e-23	107.0	COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,1HXG8@117743|Flavobacteriia	976|Bacteroidetes	N	Cell envelope biogenesis protein OmpA	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
TLS3_k127_5932159_0	886379.AEWI01000012_gene1069	3.399e-269	842.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,2FM50@200643|Bacteroidia,3XJFH@558415|Marinilabiliaceae	976|Bacteroidetes	HI	1-deoxy-D-xylulose-5-phosphate synthase	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
TLS3_k127_5932159_2	1123057.P872_01090	1.477e-101	336.0	2BZ6M@1|root,2Z7HW@2|Bacteria,4NDZE@976|Bacteroidetes,47M8V@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_5932159_9	649349.Lbys_1338	1.917e-07	56.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,47RIT@768503|Cytophagia	976|Bacteroidetes	L	Site-specific recombinase, DNA invertase Pin	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TLS3_k127_5932159_5	1122605.KB893630_gene4077	3.768e-28	123.0	COG3637@1|root,COG3637@2|Bacteria,4NRFZ@976|Bacteroidetes	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5932159_6	1408473.JHXO01000008_gene2805	6.554e-26	114.0	2FEWX@1|root,346VQ@2|Bacteria,4P654@976|Bacteroidetes,2FYU2@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5932159_4	1333523.L593_00815	3.223e-69	243.0	COG0656@1|root,arCOG01619@2157|Archaea,2XTJ4@28890|Euryarchaeota,23SMW@183963|Halobacteria	183963|Halobacteria	S	COG0656 Aldo keto reductases, related to diketogulonate reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_5932159_8	269798.CHU_1746	1.643e-19	92.0	COG1544@1|root,COG1544@2|Bacteria,4NUWT@976|Bacteroidetes,47SFR@768503|Cytophagia	976|Bacteroidetes	J	ribosomal subunit interface protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
TLS3_k127_5932159_1	1123057.P872_21215	2.522e-235	758.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,47JYI@768503|Cytophagia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
TLS3_k127_5932159_3	1124780.ANNU01000016_gene1870	2.7e-92	309.0	COG1105@1|root,COG1105@2|Bacteria,4NFZI@976|Bacteroidetes,47MVA@768503|Cytophagia	976|Bacteroidetes	H	belongs to the carbohydrate kinase PfkB family	pfkB	-	2.7.1.11,2.7.1.144	ko:K00917,ko:K16370	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
TLS3_k127_5939613_3	203275.BFO_1792	6.132e-48	177.0	COG1271@1|root,COG1271@2|Bacteria,4NG7U@976|Bacteroidetes,2FMV6@200643|Bacteroidia,22W3V@171551|Porphyromonadaceae	976|Bacteroidetes	C	oxidase, subunit	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
TLS3_k127_5939613_0	1168289.AJKI01000011_gene580	1.136e-133	436.0	COG1294@1|root,COG1294@2|Bacteria,4NHZU@976|Bacteroidetes,2FMIN@200643|Bacteroidia,3XJDS@558415|Marinilabiliaceae	976|Bacteroidetes	C	Cytochrome bd terminal oxidase subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
TLS3_k127_5939613_2	153721.MYP_4850	3.954e-49	184.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,47PCF@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
TLS3_k127_5939613_1	886379.AEWI01000046_gene3114	2.917e-50	182.0	COG0241@1|root,COG0241@2|Bacteria,4PKR5@976|Bacteroidetes,2G0BM@200643|Bacteroidia,3XJZB@558415|Marinilabiliaceae	976|Bacteroidetes	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5945490_0	1168034.FH5T_14690	8.384e-143	473.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes	976|Bacteroidetes	V	permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_5945490_2	1168034.FH5T_14695	6.196e-43	177.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes	976|Bacteroidetes	V	permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_5945490_1	1121904.ARBP01000005_gene4772	8.051e-101	344.0	COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_5970196_3	1408473.JHXO01000009_gene3387	7.405e-22	98.0	COG2852@1|root,COG2852@2|Bacteria	2|Bacteria	L	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
TLS3_k127_5970196_0	1408473.JHXO01000006_gene1310	4.184e-210	670.0	COG0043@1|root,COG0043@2|Bacteria,4NHHV@976|Bacteroidetes,2FW7Y@200643|Bacteroidia	976|Bacteroidetes	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
TLS3_k127_5970196_1	927658.AJUM01000040_gene870	2.302e-82	285.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NK8Q@976|Bacteroidetes,2FXT6@200643|Bacteroidia,3XJ4P@558415|Marinilabiliaceae	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_2,Reg_prop,SpoIIE,Y_Y_Y
TLS3_k127_5970196_2	1168289.AJKI01000011_gene442	2.383e-61	228.0	COG0642@1|root,COG0642@2|Bacteria,4P0S2@976|Bacteroidetes,2G21K@200643|Bacteroidia,3XJW5@558415|Marinilabiliaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,Response_reg
TLS3_k127_597545_2	926556.Echvi_0398	1.398e-11	65.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,47UBJ@768503|Cytophagia	976|Bacteroidetes	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
TLS3_k127_597545_0	1047013.AQSP01000142_gene184	3.254e-197	641.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_597545_1	1168034.FH5T_14690	6.35e-132	431.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes	976|Bacteroidetes	V	permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_5984637_0	760192.Halhy_4669	3.616e-260	823.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF70@976|Bacteroidetes,1IPE8@117747|Sphingobacteriia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
TLS3_k127_5984637_5	761193.Runsl_1357	2.131e-56	205.0	COG1030@1|root,COG1030@2|Bacteria,4PN0T@976|Bacteroidetes,47YFF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
TLS3_k127_5984637_3	926560.KE387025_gene4132	3.952e-70	244.0	COG2085@1|root,COG2085@2|Bacteria,1WMWM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	F420_oxidored
TLS3_k127_5984637_4	869213.JCM21142_104172	6.458e-59	213.0	COG1794@1|root,COG1794@2|Bacteria,4NI4F@976|Bacteroidetes,47UIB@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
TLS3_k127_5984637_7	1121097.JCM15093_860	9.106e-05	46.0	COG0477@1|root,COG2814@2|Bacteria,4NGAV@976|Bacteroidetes,2G0JU@200643|Bacteroidia	976|Bacteroidetes	EGP	Transmembrane secretion effector	-	-	-	ko:K08217	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22	-	-	MFS_1,MFS_3
TLS3_k127_5984637_2	927658.AJUM01000037_gene2061	2.063e-71	259.0	COG0642@1|root,COG3829@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,4NDXU@976|Bacteroidetes,2FM06@200643|Bacteroidia	976|Bacteroidetes	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_5984637_1	1121939.L861_22870	6.656e-138	447.0	COG2230@1|root,COG2230@2|Bacteria,1QY55@1224|Proteobacteria,1RYEN@1236|Gammaproteobacteria,1XNR9@135619|Oceanospirillales	135619|Oceanospirillales	M	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
TLS3_k127_5984637_6	1506583.JQJY01000008_gene3825	5.813e-28	115.0	COG2335@1|root,COG2335@2|Bacteria,4PPX7@976|Bacteroidetes,1IKWT@117743|Flavobacteriia,2P0WW@237|Flavobacterium	976|Bacteroidetes	M	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
TLS3_k127_5988275_1	1434325.AZQN01000001_gene45	3.535e-193	621.0	COG4206@1|root,COG4206@2|Bacteria,4PMK4@976|Bacteroidetes	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	Plug
TLS3_k127_5988275_0	1434325.AZQN01000001_gene46	8.707e-212	675.0	COG1435@1|root,COG1435@2|Bacteria,4NE95@976|Bacteroidetes,47M6C@768503|Cytophagia	976|Bacteroidetes	F	SusD family	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_3,SusD_RagB
TLS3_k127_5988275_2	1235803.C825_03491	1.591e-97	328.0	2BXWD@1|root,2Z7NF@2|Bacteria,4NJ6E@976|Bacteroidetes,2FM1X@200643|Bacteroidia,22Y0U@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1735)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735
TLS3_k127_6013396_3	593750.Metfor_1968	3.515e-25	106.0	COG0477@1|root,arCOG00143@2157|Archaea,2XUTR@28890|Euryarchaeota,2N94Q@224756|Methanomicrobia	224756|Methanomicrobia	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_6013396_1	457424.BFAG_02889	5.413e-85	290.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes,2FMTH@200643|Bacteroidia,4AMPM@815|Bacteroidaceae	976|Bacteroidetes	H	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
TLS3_k127_6013396_0	927658.AJUM01000037_gene1909	4.238e-102	337.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,2FMX9@200643|Bacteroidia,3XIXK@558415|Marinilabiliaceae	976|Bacteroidetes	H	Uroporphyrinogen-III synthase HemD	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
TLS3_k127_6013396_4	385682.AFSL01000096_gene595	2.912e-13	76.0	COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,2FUKM@200643|Bacteroidia,3XK7E@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribonuclease P	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
TLS3_k127_6013396_2	385682.AFSL01000060_gene1826	4.13e-81	280.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,2FM0W@200643|Bacteroidia,3XIQ1@558415|Marinilabiliaceae	976|Bacteroidetes	M	tail specific protease	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
TLS3_k127_6112200_2	1185876.BN8_00889	6.317e-94	337.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JU6@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_6112200_3	313595.P700755_001428	1.391e-07	55.0	COG1569@1|root,COG1569@2|Bacteria,4NQT0@976|Bacteroidetes	976|Bacteroidetes	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
TLS3_k127_6112200_0	1168034.FH5T_13240	1.31e-189	597.0	COG3940@1|root,COG3940@2|Bacteria,4PMUR@976|Bacteroidetes,2FNKX@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
TLS3_k127_6112200_1	1123008.KB905699_gene1946	4.842e-102	337.0	COG0738@1|root,COG0738@2|Bacteria,4NEB2@976|Bacteroidetes,2FMUT@200643|Bacteroidia,22VVA@171551|Porphyromonadaceae	976|Bacteroidetes	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_6149201_0	929562.Emtol_3881	8.614e-290	920.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,47JC0@768503|Cytophagia	976|Bacteroidetes	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_6149201_1	1168034.FH5T_04380	5.905e-123	406.0	COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,2FW97@200643|Bacteroidia	976|Bacteroidetes	E	Alanine dehydrogenase/PNT, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
TLS3_k127_6152421_1	1121904.ARBP01000019_gene2780	1.467e-211	696.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47M35@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_6152421_6	929703.KE386491_gene3875	6.551e-60	228.0	COG4198@1|root,COG4198@2|Bacteria,4NEAX@976|Bacteroidetes,47Y7F@768503|Cytophagia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
TLS3_k127_6152421_4	388413.ALPR1_17063	5.523e-159	505.0	COG0684@1|root,COG0684@2|Bacteria,4NF3M@976|Bacteroidetes,47JU7@768503|Cytophagia	976|Bacteroidetes	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
TLS3_k127_6152421_0	1288963.ADIS_2823	7.93e-243	757.0	COG4948@1|root,COG4948@2|Bacteria,4NE9A@976|Bacteroidetes,47NDY@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
TLS3_k127_6152421_3	742725.HMPREF9450_00913	1.491e-168	534.0	COG0524@1|root,COG0524@2|Bacteria,4NFH8@976|Bacteroidetes,2FMY2@200643|Bacteroidia,22V3N@171550|Rikenellaceae	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
TLS3_k127_6152421_5	1121904.ARBP01000009_gene4400	2.785e-136	445.0	COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes,47JSH@768503|Cytophagia	976|Bacteroidetes	S	PFAM Bile acid sodium symporter	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
TLS3_k127_6152421_2	1211813.CAPH01000006_gene1393	7.361e-184	583.0	COG3408@1|root,COG3408@2|Bacteria,4NESP@976|Bacteroidetes,2FMGH@200643|Bacteroidia	976|Bacteroidetes	G	Alpha-L-rhamnosidase N-terminal domain protein	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
TLS3_k127_6159631_3	755732.Fluta_3173	6.294e-15	85.0	COG0419@1|root,COG1196@1|root,COG3391@1|root,COG0419@2|Bacteria,COG1196@2|Bacteria,COG3391@2|Bacteria,4PP0U@976|Bacteroidetes,1ICPT@117743|Flavobacteriia,2PBJT@246874|Cryomorphaceae	976|Bacteroidetes	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6159631_2	1408433.JHXV01000033_gene1156	6.906e-19	89.0	COG2127@1|root,COG2127@2|Bacteria,4NS8R@976|Bacteroidetes,1I3WR@117743|Flavobacteriia,2PB69@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM ATP-dependent Clp protease adaptor protein ClpS	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
TLS3_k127_6159631_0	1168034.FH5T_00235	7.307e-142	461.0	COG0176@1|root,COG0176@2|Bacteria,4P1X0@976|Bacteroidetes,2FX3H@200643|Bacteroidia	976|Bacteroidetes	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
TLS3_k127_6159631_1	1123008.KB905694_gene1878	2.25e-81	277.0	COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,2FMSI@200643|Bacteroidia,22X8Y@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
TLS3_k127_6181070_3	743722.Sph21_2142	1.149e-62	229.0	COG0628@1|root,COG0628@2|Bacteria,4NFB2@976|Bacteroidetes,1IR5X@117747|Sphingobacteriia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS3_k127_6181070_5	1391646.AVSU01000124_gene2207	1.352e-15	87.0	COG4886@1|root,COG4886@2|Bacteria,1V3UH@1239|Firmicutes,24K2H@186801|Clostridia,25TYN@186804|Peptostreptococcaceae	186801|Clostridia	E	Leucine Rich repeats (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3888,FIVAR,LRR_4
TLS3_k127_6181070_2	946483.Cenrod_2638	2.974e-80	289.0	COG3614@1|root,COG4251@1|root,COG3614@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Phosphonate-bd,Protoglobin,Response_reg
TLS3_k127_6181070_4	1123508.JH636448_gene7645	1.106e-47	175.0	COG2764@1|root,COG2764@2|Bacteria,2IZTY@203682|Planctomycetes	203682|Planctomycetes	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS3_k127_6181070_1	1408473.JHXO01000010_gene3732	6.341e-95	328.0	COG3266@1|root,COG3266@2|Bacteria,4NMES@976|Bacteroidetes,2FU8B@200643|Bacteroidia	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6181070_0	1185876.BN8_06600	5.673e-218	680.0	COG4948@1|root,COG4948@2|Bacteria,4NI24@976|Bacteroidetes,47N24@768503|Cytophagia	976|Bacteroidetes	M	mandelate racemase muconate lactonizing	-	-	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
TLS3_k127_6185212_1	1408473.JHXO01000012_gene335	2.281e-60	213.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria,4NG7E@976|Bacteroidetes,2FQPW@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
TLS3_k127_6185212_0	1499967.BAYZ01000139_gene155	3.562e-244	767.0	COG0065@1|root,COG0065@2|Bacteria,2NNYT@2323|unclassified Bacteria	2|Bacteria	E	Aconitase family (aconitate hydratase)	leuC1	-	4.2.1.33,4.2.1.35,4.2.1.36	ko:K01703,ko:K01705	ko00290,ko00300,ko00660,ko00966,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map00966,map01100,map01110,map01120,map01130,map01210,map01230	M00030,M00432,M00433,M00535	R03896,R03898,R03968,R04001,R04371,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
TLS3_k127_6224060_2	1121012.AUKX01000032_gene692	6.756e-40	149.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1HYSB@117743|Flavobacteriia,23FQ9@178469|Arenibacter	976|Bacteroidetes	M	GDP-mannose 4,6 dehydratase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
TLS3_k127_6224060_1	1408473.JHXO01000001_gene2249	1.087e-173	550.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,2FMUH@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
TLS3_k127_6224060_0	1121129.KB903359_gene2422	1.242e-267	835.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,2FN9H@200643|Bacteroidia,22WIP@171551|Porphyromonadaceae	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
TLS3_k127_6225163_6	504472.Slin_4155	1.687e-107	356.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,47K5N@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	ybiK	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
TLS3_k127_6225163_11	1279009.ADICEAN_01509	2.091e-36	142.0	arCOG06832@1|root,31H39@2|Bacteria,4NZ65@976|Bacteroidetes,47VXI@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
TLS3_k127_6225163_4	1123008.KB905704_gene502	1.222e-134	441.0	COG1253@1|root,COG1253@2|Bacteria,4NE9R@976|Bacteroidetes,2FN9R@200643|Bacteroidia,22W70@171551|Porphyromonadaceae	976|Bacteroidetes	P	Transporter associated domain	corC_1	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
TLS3_k127_6225163_5	1168034.FH5T_14545	2.708e-132	426.0	COG0428@1|root,COG0428@2|Bacteria,4NGQ8@976|Bacteroidetes,2FQWI@200643|Bacteroidia	976|Bacteroidetes	P	Metal cation transporter, ZIP family	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
TLS3_k127_6225163_0	616991.JPOO01000003_gene792	4.674e-262	825.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,1HYJ3@117743|Flavobacteriia,23FMF@178469|Arenibacter	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_6225163_3	1123248.KB893316_gene4535	5.206e-201	640.0	COG0467@1|root,COG0467@2|Bacteria,4NKD2@976|Bacteroidetes,1IV5Y@117747|Sphingobacteriia	976|Bacteroidetes	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
TLS3_k127_6225163_12	316067.Geob_3569	4.04e-35	138.0	COG4251@1|root,COG4251@2|Bacteria,1N1KJ@1224|Proteobacteria,42W7E@68525|delta/epsilon subdivisions,2WSCW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	KaiB	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
TLS3_k127_6225163_13	316067.Geob_3568	4.851e-35	137.0	COG4251@1|root,COG4251@2|Bacteria,1N44A@1224|Proteobacteria,431XF@68525|delta/epsilon subdivisions,2WWPK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	KaiB	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
TLS3_k127_6225163_7	1220534.B655_0947	2.258e-88	313.0	arCOG02377@1|root,arCOG03931@1|root,arCOG07605@1|root,arCOG02377@2157|Archaea,arCOG03931@2157|Archaea,arCOG07605@2157|Archaea,2Y7PW@28890|Euryarchaeota	28890|Euryarchaeota	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
TLS3_k127_6225163_10	985255.APHJ01000018_gene3031	2.477e-44	170.0	COG4704@1|root,COG4704@2|Bacteria,4NUMP@976|Bacteroidetes,1I5WC@117743|Flavobacteriia	976|Bacteroidetes	S	Fibrobacter succinogenes major domain (Fib_succ_major)	-	-	-	-	-	-	-	-	-	-	-	-	BACON,Fib_succ_major
TLS3_k127_6225163_14	517417.Cpar_0886	6.465e-23	103.0	COG1051@1|root,COG1051@2|Bacteria,1FFC0@1090|Chlorobi	1090|Chlorobi	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
TLS3_k127_6225163_15	1380600.AUYN01000003_gene155	1.485e-12	72.0	2EB7H@1|root,33583@2|Bacteria,4NUPY@976|Bacteroidetes,1IBH8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6225163_2	1131812.JQMS01000001_gene463	1.027e-230	724.0	COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,1HX0B@117743|Flavobacteriia,2NTCA@237|Flavobacterium	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
TLS3_k127_6225163_8	1408433.JHXV01000006_gene2768	8.633e-82	284.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1HY5S@117743|Flavobacteriia,2PAT9@246874|Cryomorphaceae	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
TLS3_k127_6225163_9	927658.AJUM01000010_gene1360	3.447e-49	180.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,2FT2E@200643|Bacteroidia	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
TLS3_k127_6225163_1	1408473.JHXO01000007_gene810	5.43e-247	771.0	COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,2FQ86@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_6231069_9	869213.JCM21142_83257	2.225e-16	80.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,47PG1@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K01802,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
TLS3_k127_6231069_8	1288963.ADIS_4136	1.809e-16	87.0	2DNFQ@1|root,32X9Z@2|Bacteria,4PNNB@976|Bacteroidetes,47YC3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6231069_5	388413.ALPR1_13240	9.541e-92	309.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,47XP8@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
TLS3_k127_6231069_6	1123248.KB893330_gene425	5.619e-61	217.0	COG0300@1|root,COG0300@2|Bacteria,4NEFB@976|Bacteroidetes,1IQYU@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_6231069_1	927658.AJUM01000047_gene3010	6.153e-133	433.0	COG3426@1|root,COG3426@2|Bacteria,4NJBW@976|Bacteroidetes,2FMMN@200643|Bacteroidia,3XIXX@558415|Marinilabiliaceae	976|Bacteroidetes	C	Acetokinase family	buk	-	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
TLS3_k127_6231069_3	869213.JCM21142_52148	1.827e-101	338.0	COG0280@1|root,COG0280@2|Bacteria,4NJPR@976|Bacteroidetes	976|Bacteroidetes	C	phosphate butyryltransferase	ptb	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	PTA_PTB
TLS3_k127_6231069_2	869213.JCM21142_52147	2.381e-123	402.0	COG0280@1|root,COG0280@2|Bacteria,4NJPR@976|Bacteroidetes	976|Bacteroidetes	C	phosphate butyryltransferase	ptb	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	PTA_PTB
TLS3_k127_6231069_0	1168289.AJKI01000015_gene2214	1.035e-179	570.0	COG0282@1|root,COG0282@2|Bacteria,4NFI0@976|Bacteroidetes,2FN9W@200643|Bacteroidia,3XJG7@558415|Marinilabiliaceae	976|Bacteroidetes	C	Acetokinase family	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
TLS3_k127_6231069_4	927658.AJUM01000047_gene3013	4.726e-100	335.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,2FPSD@200643|Bacteroidia,3XIY5@558415|Marinilabiliaceae	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
TLS3_k127_6231069_7	869213.JCM21142_52144	1.271e-55	196.0	COG0280@1|root,COG0280@2|Bacteria,4NGX5@976|Bacteroidetes,47KUW@768503|Cytophagia	976|Bacteroidetes	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
TLS3_k127_6235855_7	1168034.FH5T_20085	4.067e-49	182.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,2FNRV@200643|Bacteroidia	976|Bacteroidetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
TLS3_k127_6235855_5	1008457.BAEX01000055_gene627	2.427e-85	293.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1HX3D@117743|Flavobacteriia,47HUY@76831|Myroides	976|Bacteroidetes	S	DHH family	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
TLS3_k127_6235855_8	886379.AEWI01000013_gene2031	2.365e-40	156.0	COG0545@1|root,COG0545@2|Bacteria,4NV96@976|Bacteroidetes,2FZV9@200643|Bacteroidia,3XK5D@558415|Marinilabiliaceae	976|Bacteroidetes	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
TLS3_k127_6235855_9	468059.AUHA01000002_gene260	5.682e-20	96.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,1IQ1U@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM FKBP-type peptidyl-prolyl cis-trans isomerase	ppiB	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
TLS3_k127_6235855_6	1502770.JQMG01000001_gene2004	4.81e-69	241.0	COG0313@1|root,COG0313@2|Bacteria,1RARW@1224|Proteobacteria,2VQ34@28216|Betaproteobacteria,2KKRK@206350|Nitrosomonadales	206350|Nitrosomonadales	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	-	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
TLS3_k127_6235855_4	927658.AJUM01000047_gene2887	1.362e-95	323.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,2FN0W@200643|Bacteroidia,3XIST@558415|Marinilabiliaceae	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	lipB	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
TLS3_k127_6235855_0	1239962.C943_01005	3.355e-266	848.0	COG1262@1|root,COG1262@2|Bacteria,4NJRT@976|Bacteroidetes,47TU9@768503|Cytophagia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TLS3_k127_6235855_2	385682.AFSL01000044_gene359	8.491e-136	443.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,2FNGC@200643|Bacteroidia,3XKC7@558415|Marinilabiliaceae	976|Bacteroidetes	G	Galactokinase galactose-binding signature	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
TLS3_k127_6235855_1	1408473.JHXO01000009_gene3355	7.973e-229	715.0	COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,2FNPD@200643|Bacteroidia	976|Bacteroidetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
TLS3_k127_6244806_10	945713.IALB_0443	2.818e-50	189.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
TLS3_k127_6244806_8	1191523.MROS_0359	3.124e-76	267.0	COG2972@1|root,COG2972@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
TLS3_k127_6244806_4	927658.AJUM01000042_gene1686	1.664e-80	276.0	COG3279@1|root,COG3279@2|Bacteria,4NEAH@976|Bacteroidetes,2FWA7@200643|Bacteroidia,3XJ7S@558415|Marinilabiliaceae	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_6244806_12	1408473.JHXO01000001_gene2280	1.062e-22	100.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,2FTU6@200643|Bacteroidia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
TLS3_k127_6244806_1	1158294.JOMI01000004_gene3375	1.753e-91	305.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,2FPBQ@200643|Bacteroidia	976|Bacteroidetes	S	neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
TLS3_k127_6244806_7	385682.AFSL01000096_gene582	1.457e-76	271.0	2C2F5@1|root,32WND@2|Bacteria,4NNJR@976|Bacteroidetes,2FTPA@200643|Bacteroidia,3XK9H@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6244806_2	1408473.JHXO01000005_gene1475	3.429e-91	305.0	COG1136@1|root,COG1136@2|Bacteria,4NGY1@976|Bacteroidetes,2FRNC@200643|Bacteroidia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_6244806_6	1121904.ARBP01000002_gene6768	4.402e-77	276.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_6244806_0	1408473.JHXO01000005_gene1473	2.5e-92	320.0	COG4591@1|root,COG4591@2|Bacteria,4NGJ3@976|Bacteroidetes,2FS1D@200643|Bacteroidia	976|Bacteroidetes	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_6244806_5	1408473.JHXO01000005_gene1472	5.76e-78	268.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,2FSCB@200643|Bacteroidia	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
TLS3_k127_6244806_3	1168289.AJKI01000007_gene175	5.462e-85	299.0	COG2273@1|root,COG2273@2|Bacteria,4NQU3@976|Bacteroidetes,2FT4I@200643|Bacteroidia,3XJ9K@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
TLS3_k127_6244806_9	1168289.AJKI01000002_gene2553	2.034e-53	192.0	COG1595@1|root,COG1595@2|Bacteria,4NQ7S@976|Bacteroidetes,2FTDI@200643|Bacteroidia,3XK6J@558415|Marinilabiliaceae	976|Bacteroidetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_6244806_13	385682.AFSL01000060_gene1813	9.692e-12	76.0	2DP4F@1|root,330H1@2|Bacteria,4NX9Z@976|Bacteroidetes,2FVZZ@200643|Bacteroidia,3XKEM@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6244806_11	869213.JCM21142_93407	3.209e-41	165.0	COG0515@1|root,COG0515@2|Bacteria	869213.JCM21142_93407|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6258310_0	1122176.KB903549_gene1226	1.871e-115	398.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes	976|Bacteroidetes	T	histidine kinase-, DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
TLS3_k127_6271376_1	1168034.FH5T_05700	1.439e-79	273.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,2FN92@200643|Bacteroidia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_6271376_0	927658.AJUM01000034_gene127	1.699e-135	439.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,2FQNC@200643|Bacteroidia,3XJTF@558415|Marinilabiliaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TLS3_k127_6277505_1	411477.PARMER_03216	9.104e-156	511.0	28I1E@1|root,2Z862@2|Bacteria,4NGDW@976|Bacteroidetes,2FPGS@200643|Bacteroidia,22ZCE@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
TLS3_k127_6277505_3	1121481.AUAS01000021_gene2870	1.646e-119	396.0	COG1506@1|root,COG1506@2|Bacteria,4PKQ3@976|Bacteroidetes,47XYQ@768503|Cytophagia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_6277505_2	929562.Emtol_1032	4.098e-120	394.0	COG2055@1|root,COG2055@2|Bacteria,4NGVC@976|Bacteroidetes,47MHU@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	1.1.1.130	ko:K08092	ko00040,ko00053,map00040,map00053	-	R02637,R02639	RC00238	ko00000,ko00001,ko01000	-	-	-	Ldh_2
TLS3_k127_6277505_4	1168034.FH5T_16785	1.428e-99	331.0	COG2133@1|root,COG2133@2|Bacteria,4NGMS@976|Bacteroidetes,2FQQN@200643|Bacteroidia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_6277505_0	1408473.JHXO01000001_gene2486	2.248e-252	785.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FP28@200643|Bacteroidia	976|Bacteroidetes	S	Tat pathway signal sequence domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_6277505_5	655815.ZPR_4658	1.207e-98	328.0	COG2133@1|root,COG2133@2|Bacteria,4PKJE@976|Bacteroidetes,1IKAY@117743|Flavobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_6277505_6	1121405.dsmv_0100	7.948e-88	293.0	COG2316@1|root,COG2316@2|Bacteria,1RA50@1224|Proteobacteria,42QZZ@68525|delta/epsilon subdivisions,2WMUN@28221|Deltaproteobacteria,2MJHQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
TLS3_k127_628584_7	865937.Gilli_2019	2.838e-39	149.0	COG2866@1|root,COG2866@2|Bacteria,4NH4I@976|Bacteroidetes,1I15Z@117743|Flavobacteriia	976|Bacteroidetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
TLS3_k127_628584_1	929703.KE386491_gene756	1.931e-134	446.0	COG2866@1|root,COG2866@2|Bacteria,4NHBS@976|Bacteroidetes,47MR4@768503|Cytophagia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
TLS3_k127_628584_4	742726.HMPREF9448_01957	2.205e-61	222.0	COG0803@1|root,COG0803@2|Bacteria,4NGMC@976|Bacteroidetes,2FMQR@200643|Bacteroidia,22XUG@171551|Porphyromonadaceae	976|Bacteroidetes	P	Zinc-uptake complex component A periplasmic	mntA	-	-	ko:K09815,ko:K11707	ko02010,map02010	M00242,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
TLS3_k127_628584_2	1121129.KB903367_gene2837	7.803e-84	284.0	COG1121@1|root,COG1121@2|Bacteria,4NHZ9@976|Bacteroidetes,2FM2P@200643|Bacteroidia,22VV3@171551|Porphyromonadaceae	976|Bacteroidetes	P	ABC transporter, ATP-binding protein	znuC	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
TLS3_k127_628584_3	1408473.JHXO01000001_gene2283	9.8e-83	283.0	COG1108@1|root,COG1108@2|Bacteria,4NH3D@976|Bacteroidetes,2FNK0@200643|Bacteroidia	976|Bacteroidetes	P	ABC 3 transport family protein	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
TLS3_k127_628584_0	1168034.FH5T_12570	3.843e-228	713.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,2FM8Y@200643|Bacteroidia	976|Bacteroidetes	C	Dihydrolipoyl dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_628584_6	1408473.JHXO01000006_gene1104	1.165e-55	200.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,2G2VX@200643|Bacteroidia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_628584_8	1249997.JHZW01000002_gene970	9.72e-31	136.0	COG3266@1|root,COG3266@2|Bacteria,4NH1U@976|Bacteroidetes,1HX0D@117743|Flavobacteriia,2PI9R@252356|Maribacter	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_628584_5	616991.JPOO01000003_gene224	9.281e-57	204.0	COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,1HXX8@117743|Flavobacteriia,23GMJ@178469|Arenibacter	976|Bacteroidetes	M	Transglycosylase SLT domain	mltD_2	-	-	-	-	-	-	-	-	-	-	-	SLT
TLS3_k127_6319227_1	1121904.ARBP01000015_gene179	1.786e-228	730.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_6319227_2	1121396.KB893077_gene750	6.962e-37	150.0	COG3315@1|root,COG3315@2|Bacteria,1RAX6@1224|Proteobacteria,42SC3@68525|delta/epsilon subdivisions,2X5Q6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
TLS3_k127_6319227_0	694427.Palpr_0316	1.486e-273	864.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,2FS4M@200643|Bacteroidia,2309R@171551|Porphyromonadaceae	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_6319227_3	746697.Aeqsu_0351	6.736e-31	136.0	COG2207@1|root,COG2207@2|Bacteria,4NG1D@976|Bacteroidetes,1HY6X@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_6326166_0	1408473.JHXO01000001_gene2440	3.775e-110	367.0	COG1785@1|root,COG1785@2|Bacteria,4NG3D@976|Bacteroidetes,2FMNA@200643|Bacteroidia	976|Bacteroidetes	P	Belongs to the alkaline phosphatase family	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
TLS3_k127_6326166_2	1121897.AUGO01000006_gene827	5.623e-61	216.0	COG2207@1|root,COG2207@2|Bacteria,4NMXA@976|Bacteroidetes,1I1NA@117743|Flavobacteriia,2NU54@237|Flavobacterium	976|Bacteroidetes	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_6326166_6	929556.Solca_0884	9.363e-19	87.0	COG3237@1|root,COG3237@2|Bacteria,4NUMZ@976|Bacteroidetes,1ITX1@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
TLS3_k127_6326166_3	1121890.AUDO01000004_gene2148	4.53e-56	201.0	2DIFQ@1|root,30348@2|Bacteria,4NNAK@976|Bacteroidetes,1I9F7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6326166_5	1484460.JSWG01000009_gene294	6.369e-36	158.0	COG2982@1|root,COG2982@2|Bacteria,4NHBK@976|Bacteroidetes,1I04H@117743|Flavobacteriia	976|Bacteroidetes	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
TLS3_k127_6326166_4	1270193.JARP01000001_gene2955	1.733e-51	187.0	COG3685@1|root,COG3685@2|Bacteria,4NMCT@976|Bacteroidetes,1I1BM@117743|Flavobacteriia,2NUHM@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
TLS3_k127_6326166_7	1249975.JQLP01000005_gene2000	8.919e-10	62.0	COG4980@1|root,COG4980@2|Bacteria,4NU4D@976|Bacteroidetes,1I4FT@117743|Flavobacteriia,2P6ZY@244698|Gillisia	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
TLS3_k127_6326166_1	1121890.AUDO01000007_gene2436	1.823e-70	245.0	COG1295@1|root,COG1295@2|Bacteria,4NFG8@976|Bacteroidetes,1HX47@117743|Flavobacteriia,2NTZS@237|Flavobacterium	976|Bacteroidetes	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
TLS3_k127_6326935_7	1499967.BAYZ01000026_gene1627	5.986e-20	92.0	2DTJ5@1|root,33KM4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6326935_5	742727.HMPREF9447_00173	2.018e-59	219.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,2FPUC@200643|Bacteroidia,4AN73@815|Bacteroidaceae	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_6326935_3	1235803.C825_04396	1.69e-86	293.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,2FMKB@200643|Bacteroidia,22XZT@171551|Porphyromonadaceae	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_6326935_2	504472.Slin_4020	2.86e-118	388.0	COG0657@1|root,COG0657@2|Bacteria,4NIQ0@976|Bacteroidetes,47JK6@768503|Cytophagia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
TLS3_k127_6326935_1	1121930.AQXG01000001_gene1102	1.693e-123	411.0	COG2091@1|root,COG2091@2|Bacteria,4NGXG@976|Bacteroidetes	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_6326935_6	1121930.AQXG01000001_gene1102	1.186e-45	176.0	COG2091@1|root,COG2091@2|Bacteria,4NGXG@976|Bacteroidetes	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_6326935_0	1123278.KB893616_gene3408	5.345e-147	484.0	COG3119@1|root,COG3119@2|Bacteria,4NE9D@976|Bacteroidetes,47T9R@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TLS3_k127_6326935_4	1120965.AUBV01000006_gene2349	1.345e-69	240.0	COG3119@1|root,COG3119@2|Bacteria,4NGJU@976|Bacteroidetes,47MMU@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TLS3_k127_6327216_1	1123248.KB893317_gene4310	1.072e-47	174.0	COG3145@1|root,COG3145@2|Bacteria	2|Bacteria	L	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
TLS3_k127_6327216_4	1168034.FH5T_19355	1.86e-36	148.0	COG1387@1|root,COG1387@2|Bacteria,4NMBC@976|Bacteroidetes,2FNU7@200643|Bacteroidia	976|Bacteroidetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_6327216_3	525257.HMPREF0204_12324	6.319e-37	150.0	2ES9M@1|root,33JUC@2|Bacteria,4NYGV@976|Bacteroidetes	976|Bacteroidetes	S	Peptidase C10 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C10
TLS3_k127_6327216_2	313606.M23134_04103	1.111e-41	168.0	COG2207@1|root,COG2207@2|Bacteria,4NHEJ@976|Bacteroidetes,47MRE@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_6327216_0	880074.BARVI_05115	3.234e-97	320.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,2FMW7@200643|Bacteroidia,22VV9@171551|Porphyromonadaceae	976|Bacteroidetes	S	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_6347467_3	1168034.FH5T_14990	4.251e-30	122.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,2G2YY@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
TLS3_k127_6347467_4	1235803.C825_04638	2.916e-20	96.0	COG3093@1|root,COG3093@2|Bacteria,4NSDG@976|Bacteroidetes,2FSS7@200643|Bacteroidia,22YQ7@171551|Porphyromonadaceae	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Phage_CI_repr
TLS3_k127_6347467_2	1227272.HMPREF1556_01893	4.872e-56	205.0	COG0543@1|root,COG0543@2|Bacteria,4NE35@976|Bacteroidetes,2FN69@200643|Bacteroidia,22WHB@171551|Porphyromonadaceae	976|Bacteroidetes	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
TLS3_k127_6347467_0	411901.BACCAC_00567	1.184e-130	422.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,2FPMW@200643|Bacteroidia,4AKT8@815|Bacteroidaceae	976|Bacteroidetes	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.98.1	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01867,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
TLS3_k127_6347467_1	927658.AJUM01000044_gene607	4.152e-60	211.0	COG1522@1|root,COG1522@2|Bacteria,4NMEN@976|Bacteroidetes,2FPN5@200643|Bacteroidia,3XJB2@558415|Marinilabiliaceae	976|Bacteroidetes	K	helix_turn_helix ASNC type	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
TLS3_k127_6347467_5	1203611.KB894549_gene2300	4.705e-14	73.0	COG4221@1|root,COG4221@2|Bacteria,4PKGY@976|Bacteroidetes,2FSDE@200643|Bacteroidia,22U7X@171550|Rikenellaceae	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_6348462_4	1239415.CM001837_gene2358	1.424e-58	214.0	COG1629@1|root,COG1629@2|Bacteria,4PM72@976|Bacteroidetes,1HXYQ@117743|Flavobacteriia,37DXJ@326319|Dokdonia	976|Bacteroidetes	P	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,DUF4139,DUF4140,Plug
TLS3_k127_6348462_2	869213.JCM21142_103	7.022e-116	383.0	COG3239@1|root,COG3239@2|Bacteria,4NNB2@976|Bacteroidetes	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_6348462_5	1168289.AJKI01000046_gene898	8.99e-50	188.0	COG3279@1|root,COG3279@2|Bacteria,4NJ3A@976|Bacteroidetes,2G2UX@200643|Bacteroidia	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
TLS3_k127_6348462_1	761193.Runsl_1905	1.69e-125	414.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,47JQ6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273,ko:K01274	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_C26,Peptidase_M19
TLS3_k127_6348462_0	926549.KI421517_gene3691	8.884e-140	452.0	COG0346@1|root,COG0346@2|Bacteria,4NDVG@976|Bacteroidetes,47MTQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
TLS3_k127_6348462_3	1168034.FH5T_19565	1.713e-77	267.0	COG0300@1|root,COG0300@2|Bacteria,4NEMK@976|Bacteroidetes,2G0DY@200643|Bacteroidia	976|Bacteroidetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_6363934_3	1121904.ARBP01000006_gene4071	1.407e-23	106.0	COG1629@1|root,COG2373@1|root,COG1629@2|Bacteria,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47KSH@768503|Cytophagia	976|Bacteroidetes	P	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,CarbopepD_reg_2,Plug
TLS3_k127_6363934_2	945713.IALB_0031	5.852e-29	122.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2
TLS3_k127_6363934_0	525257.HMPREF0204_12591	2.281e-222	715.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1I0B3@117743|Flavobacteriia,3ZS28@59732|Chryseobacterium	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
TLS3_k127_6363934_1	1232410.KI421421_gene3690	3.62e-44	162.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria,43S6P@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TLS3_k127_638487_3	153721.MYP_1744	1.322e-06	53.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,47JHV@768503|Cytophagia	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
TLS3_k127_638487_2	1168034.FH5T_20665	1.77e-50	191.0	COG1216@1|root,COG1216@2|Bacteria,4NQ7P@976|Bacteroidetes,2G0YA@200643|Bacteroidia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_638487_1	1408473.JHXO01000010_gene3779	1.501e-60	218.0	COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,2FV2H@200643|Bacteroidia	976|Bacteroidetes	H	2-phosphosulpholactate phosphatase	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
TLS3_k127_638487_0	56780.SYN_02541	7.724e-100	341.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,2MQRA@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
TLS3_k127_638487_4	411477.PARMER_04113	1.219e-05	52.0	COG2830@1|root,COG2830@2|Bacteria,4NSQK@976|Bacteroidetes,2FTTG@200643|Bacteroidia,22YIE@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function (DUF452)	-	-	3.1.1.85	ko:K09789	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF452
TLS3_k127_6396035_3	755732.Fluta_0154	4.478e-24	102.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,1HWW2@117743|Flavobacteriia,2PAD6@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_6396035_5	768704.Desmer_1458	6.076e-09	65.0	COG3381@1|root,COG3381@2|Bacteria,1VE7Q@1239|Firmicutes,25DPP@186801|Clostridia,2679B@186807|Peptococcaceae	186801|Clostridia	S	PFAM Nitrate reductase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
TLS3_k127_6396035_1	153721.MYP_2837	1.586e-46	172.0	COG3832@1|root,COG3832@2|Bacteria,4PKNU@976|Bacteroidetes,47QK4@768503|Cytophagia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_6396035_4	1243664.CAVL020000015_gene1871	5.635e-24	113.0	COG2273@1|root,COG2273@2|Bacteria,1UA30@1239|Firmicutes,4IKCF@91061|Bacilli,1ZGF5@1386|Bacillus	91061|Bacilli	G	Hydrolase Family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
TLS3_k127_6396035_2	694427.Palpr_0201	1.391e-40	155.0	COG3467@1|root,COG3467@2|Bacteria,4NPGX@976|Bacteroidetes,2FSZ2@200643|Bacteroidia,22YF9@171551|Porphyromonadaceae	976|Bacteroidetes	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
TLS3_k127_6396035_0	246194.CHY_1281	1.509e-91	308.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,42FCT@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM PP-loop domain protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	NAD_synthase
TLS3_k127_6411556_2	221103.XP_007852868.1	9.289e-10	61.0	28QNI@1|root,2QXBB@2759|Eukaryota,38G4M@33154|Opisthokonta,3NYTR@4751|Fungi,3VC08@5204|Basidiomycota,22F3C@155619|Agaricomycetes	4751|Fungi	S	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1593
TLS3_k127_6411556_1	1123057.P872_15910	1.637e-123	403.0	COG1957@1|root,COG1957@2|Bacteria,4NQ07@976|Bacteroidetes,47QT4@768503|Cytophagia	976|Bacteroidetes	F	Inosine-uridine preferring nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
TLS3_k127_6411556_0	1121875.KB907551_gene1032	4.458e-225	710.0	COG2730@1|root,COG2730@2|Bacteria,4NJM9@976|Bacteroidetes	976|Bacteroidetes	G	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
TLS3_k127_6413173_1	886379.AEWI01000016_gene1522	6.79e-50	190.0	COG0382@1|root,COG0382@2|Bacteria,4NFRM@976|Bacteroidetes,2FSPD@200643|Bacteroidia,3XIQE@558415|Marinilabiliaceae	976|Bacteroidetes	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
TLS3_k127_6413173_0	869213.JCM21142_3874	4.278e-58	206.0	COG1778@1|root,COG1778@2|Bacteria,4NMHD@976|Bacteroidetes,47QBU@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_3
TLS3_k127_6413173_2	445970.ALIPUT_01141	1.031e-46	183.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,2FMCQ@200643|Bacteroidia	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
TLS3_k127_6490055_0	504472.Slin_6449	1.238e-104	351.0	COG4354@1|root,COG4354@2|Bacteria,4NFQW@976|Bacteroidetes,47P0Q@768503|Cytophagia	976|Bacteroidetes	G	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term	-	-	3.2.1.45	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH116	-	DUF608,Glyco_hydr_116N
TLS3_k127_6490055_2	1270196.JCKI01000001_gene4106	4.04e-40	161.0	2EERZ@1|root,338JN@2|Bacteria,4NTN7@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF1735)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,DUF4361
TLS3_k127_6490055_1	1121481.AUAS01000001_gene4444	2.927e-60	228.0	COG0521@1|root,COG0521@2|Bacteria,4NHV5@976|Bacteroidetes,47MJ0@768503|Cytophagia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
TLS3_k127_6519668_2	869213.JCM21142_104117	5.335e-22	99.0	COG1611@1|root,COG1611@2|Bacteria,4NGWU@976|Bacteroidetes,47Q15@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
TLS3_k127_6519668_1	709991.Odosp_2970	1.179e-47	172.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,2FTV5@200643|Bacteroidia,22YCQ@171551|Porphyromonadaceae	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
TLS3_k127_6519668_0	742725.HMPREF9450_02249	8.484e-277	868.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,2FNND@200643|Bacteroidia,22UBQ@171550|Rikenellaceae	976|Bacteroidetes	L	DNA polymerase alpha chain like domain	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
TLS3_k127_6569183_3	1196322.A370_04667	1.287e-09	59.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia,36E87@31979|Clostridiaceae	186801|Clostridia	P	transport protein CorA	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
TLS3_k127_6569183_1	313598.MED152_13359	4.552e-80	277.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1HXMD@117743|Flavobacteriia,3VVV6@52959|Polaribacter	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6569183_2	435591.BDI_1688	4.205e-54	194.0	COG1443@1|root,COG1443@2|Bacteria,4NJUP@976|Bacteroidetes,2FNMR@200643|Bacteroidia,22XUF@171551|Porphyromonadaceae	976|Bacteroidetes	I	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	IspA,NUDIX
TLS3_k127_6569183_0	1279009.ADICEAN_00942	5.028e-98	328.0	COG4953@1|root,COG4953@2|Bacteria,4NEG5@976|Bacteroidetes,47KYC@768503|Cytophagia	976|Bacteroidetes	M	penicillin-binding protein 1C	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
TLS3_k127_6576648_2	1279009.ADICEAN_02422	6.223e-18	89.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,47RHF@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
TLS3_k127_6576648_0	886379.AEWI01000018_gene1291	1.704e-140	462.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,4NKA5@976|Bacteroidetes,2FRBU@200643|Bacteroidia,3XJT2@558415|Marinilabiliaceae	976|Bacteroidetes	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
TLS3_k127_6576648_1	1211813.CAPH01000006_gene1552	5.651e-45	166.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,2FKZZ@200643|Bacteroidia,22UQ7@171550|Rikenellaceae	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
TLS3_k127_6585816_8	1191523.MROS_1275	1.843e-81	279.0	COG0457@1|root,COG0457@2|Bacteria	1191523.MROS_1275|-	S	peptidyl-tyrosine sulfation	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
TLS3_k127_6585816_7	1408473.JHXO01000007_gene763	2.426e-93	311.0	COG4912@1|root,COG4912@2|Bacteria,4NHAJ@976|Bacteroidetes,2G32T@200643|Bacteroidia	976|Bacteroidetes	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
TLS3_k127_6585816_0	1121904.ARBP01000011_gene1418	7.529e-260	811.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,47K06@768503|Cytophagia	976|Bacteroidetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
TLS3_k127_6585816_6	1150600.ADIARSV_3159	8.415e-97	323.0	COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	ehrS	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2596	Fer4,Fer4_15,Fer4_7,Oxidored_q6
TLS3_k127_6585816_3	908612.HMPREF9720_1992	6.386e-129	428.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,4P295@976|Bacteroidetes,2G1PF@200643|Bacteroidia,22U63@171550|Rikenellaceae	976|Bacteroidetes	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa
TLS3_k127_6585816_2	1150600.ADIARSV_0900	7.097e-161	519.0	COG0651@1|root,COG0651@2|Bacteria,4P1B6@976|Bacteroidetes	976|Bacteroidetes	CP	Proton-conducting membrane transporter	-	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
TLS3_k127_6585816_9	1150600.ADIARSV_0899	4.8e-36	145.0	COG4237@1|root,COG4237@2|Bacteria,4P642@976|Bacteroidetes	976|Bacteroidetes	C	Hydrogenase 4 membrane	-	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
TLS3_k127_6585816_5	1150600.ADIARSV_0898	8.383e-118	385.0	COG0650@1|root,COG0650@2|Bacteria,4P2YM@976|Bacteroidetes	976|Bacteroidetes	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
TLS3_k127_6585816_4	1150600.ADIARSV_0897	8.567e-128	434.0	COG0651@1|root,COG0651@2|Bacteria	2|Bacteria	CP	ATP synthesis coupled electron transport	hyfB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K12137,ko:K15828	-	-	-	-	ko00000,ko01000	-	-	iB21_1397.B21_02538,iECBD_1354.ECBD_1002,iECB_1328.ECB_02573,iECD_1391.ECD_02573,iECED1_1282.ECED1_3174,iECO111_1330.ECO111_3443,iECO26_1355.ECO26_3788,iECP_1309.ECP_2686,iEKO11_1354.EKO11_1252,iEcHS_1320.EcHS_A2859,iLF82_1304.LF82_1065,iNRG857_1313.NRG857_13330	Proton_antipo_M,Proton_antipo_N
TLS3_k127_6585816_1	946077.W5A_12811	2.146e-173	552.0	COG3263@1|root,COG3263@2|Bacteria,4NFNS@976|Bacteroidetes,1IJ9K@117743|Flavobacteriia	976|Bacteroidetes	P	COGs COG3263 NhaP-type Na H and K H antiporter with a unique C-terminal domain	cvrA	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
TLS3_k127_6615874_1	1123008.KB905695_gene2737	2.229e-155	498.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,2FMXX@200643|Bacteroidia,22WNA@171551|Porphyromonadaceae	976|Bacteroidetes	S	Peptidase family M49	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M49
TLS3_k127_6615874_0	1408473.JHXO01000007_gene788	3.67e-156	506.0	COG2176@1|root,COG2176@2|Bacteria,4PM8C@976|Bacteroidetes,2FW8F@200643|Bacteroidia	976|Bacteroidetes	L	GIY-YIG type nucleases (URI domain)	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
TLS3_k127_6615874_2	1216932.CM240_1553	7.869e-63	225.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25930@186801|Clostridia,36DVP@31979|Clostridiaceae	186801|Clostridia	EH	Aminotransferase class IV	ilvE2	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_6616487_6	1227266.HMPREF1551_02668	6.57e-05	53.0	COG4206@1|root,COG4206@2|Bacteria,4NGYD@976|Bacteroidetes,1IJDB@117743|Flavobacteriia,1EQ3F@1016|Capnocytophaga	976|Bacteroidetes	H	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
TLS3_k127_6616487_0	927658.AJUM01000012_gene2713	1.618e-317	982.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,2FPG7@200643|Bacteroidia,3XIY4@558415|Marinilabiliaceae	976|Bacteroidetes	L	TopoisomeraseII	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
TLS3_k127_6616487_4	1408473.JHXO01000004_gene219	1.118e-88	310.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,2FM0Y@200643|Bacteroidia	976|Bacteroidetes	M	COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
TLS3_k127_6616487_2	1408473.JHXO01000001_gene2277	1.372e-140	454.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,2FPJH@200643|Bacteroidia	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
TLS3_k127_6616487_3	1168034.FH5T_20505	3.135e-124	413.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,2FMUA@200643|Bacteroidia	976|Bacteroidetes	O	peptidase Do	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
TLS3_k127_6616487_1	1168034.FH5T_20510	7.796e-158	501.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,2FNVQ@200643|Bacteroidia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS3_k127_6616487_5	886379.AEWI01000137_gene2260	1.183e-42	157.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,2FNBD@200643|Bacteroidia,3XJ69@558415|Marinilabiliaceae	976|Bacteroidetes	L	Ultra-violet resistance protein B	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
TLS3_k127_6628035_0	1408473.JHXO01000001_gene2022	5.748e-151	488.0	COG0845@1|root,COG0845@2|Bacteria,4NDUH@976|Bacteroidetes,2FM9Q@200643|Bacteroidia	976|Bacteroidetes	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS3_k127_6628035_2	742817.HMPREF9449_02308	1.313e-109	357.0	COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,2FMDA@200643|Bacteroidia,22W90@171551|Porphyromonadaceae	976|Bacteroidetes	V	bacteriocin export ABC transporter, lactococcin 972 group	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_6628035_1	1168034.FH5T_07580	6.556e-128	417.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FMRV@200643|Bacteroidia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_6631371_0	1211813.CAPH01000007_gene1774	3.431e-84	284.0	COG4221@1|root,COG4221@2|Bacteria,4PKGY@976|Bacteroidetes,2FSDE@200643|Bacteroidia,22U7X@171550|Rikenellaceae	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_6631371_2	313606.M23134_04590	1.36e-29	124.0	COG1595@1|root,COG1595@2|Bacteria,4NMJ7@976|Bacteroidetes,47PC1@768503|Cytophagia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_6631371_5	1168034.FH5T_16475	8.288e-12	73.0	2ER78@1|root,33ISU@2|Bacteria,4NZKM@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6631371_1	1121930.AQXG01000001_gene1572	9.188e-51	194.0	28J2U@1|root,2Z8Z5@2|Bacteria,4NHYM@976|Bacteroidetes,1IUG2@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6643901_1	411479.BACUNI_04697	0.0	1024.0	COG3386@1|root,COG3386@2|Bacteria,4PMW0@976|Bacteroidetes,2FW62@200643|Bacteroidia,4AT1W@815|Bacteroidaceae	976|Bacteroidetes	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3,SGL
TLS3_k127_6643901_2	1123508.JH636439_gene821	2.811e-272	862.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
TLS3_k127_6643901_4	1288963.ADIS_1999	4.698e-104	347.0	COG1957@1|root,COG1957@2|Bacteria,4NJ4J@976|Bacteroidetes,47KD9@768503|Cytophagia	976|Bacteroidetes	F	Inosine-uridine preferring nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
TLS3_k127_6643901_0	1408473.JHXO01000004_gene27	0.0	1212.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FMCU@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
TLS3_k127_6643901_3	1453498.LG45_15555	2.369e-247	773.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1HZCT@117743|Flavobacteriia,2NTX8@237|Flavobacterium	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
TLS3_k127_6644048_4	1123277.KB893244_gene5131	0.0001754	45.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,47U25@768503|Cytophagia	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.23	ko:K13019	ko00520,map00520	-	R09600	RC00290	ko00000,ko00001,ko01000,ko01005	-	-	-	Epimerase_2
TLS3_k127_6644048_0	1408473.JHXO01000009_gene3365	6.756e-246	767.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,2FKZ6@200643|Bacteroidia	976|Bacteroidetes	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
TLS3_k127_6644048_2	385682.AFSL01000088_gene886	2.402e-34	133.0	COG3027@1|root,COG3027@2|Bacteria,4NSA5@976|Bacteroidetes,2FUYF@200643|Bacteroidia,3XK9F@558415|Marinilabiliaceae	976|Bacteroidetes	D	Cell division protein ZapA	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
TLS3_k127_6644048_1	1408813.AYMG01000028_gene2446	1.647e-114	387.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1INUW@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_6688672_1	435591.BDI_2050	1.61e-187	591.0	COG0673@1|root,COG0673@2|Bacteria,4NGGS@976|Bacteroidetes,2FTQH@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_6688672_0	742725.HMPREF9450_01887	0.0	1115.0	COG3250@1|root,COG3250@2|Bacteria,4NFPC@976|Bacteroidetes,2FXA5@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	cbgA_1	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
TLS3_k127_6717177_0	1408473.JHXO01000001_gene2502	5.563e-109	375.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
TLS3_k127_6717177_1	1454007.JAUG01000102_gene1423	4.291e-55	205.0	COG0561@1|root,COG0561@2|Bacteria,4PMH7@976|Bacteroidetes	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_6746383_0	521045.Kole_0568	1.654e-148	479.0	COG3261@1|root,COG3261@2|Bacteria	2|Bacteria	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_49kDa,NiFeSe_Hases
TLS3_k127_6746383_4	521045.Kole_0569	1.929e-15	82.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
TLS3_k127_6746383_2	521045.Kole_0570	5.071e-51	186.0	COG3260@1|root,COG3260@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	echC	-	1.6.5.3	ko:K00331,ko:K14088,ko:K14105	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
TLS3_k127_6746383_1	857293.CAAU_1262	3.806e-54	202.0	COG1005@1|root,COG1005@2|Bacteria,1TQNU@1239|Firmicutes,25E6Z@186801|Clostridia,36EBY@31979|Clostridiaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
TLS3_k127_6746383_3	521045.Kole_0572	2.168e-20	97.0	COG1142@1|root,COG1142@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	hydN	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044464,GO:0055114	-	ko:K00196,ko:K05796,ko:K12136,ko:K15827	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	-	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko01000	-	-	iAF1260.b2724,iBWG_1329.BWG_2460,iE2348C_1286.E2348C_2989,iEC042_1314.EC042_2918,iECABU_c1320.ECABU_c29950,iECDH10B_1368.ECDH10B_2892,iECDH1ME8569_1439.ECDH1ME8569_2634,iECED1_1282.ECED1_3175,iECO111_1330.ECO111_3444,iECO26_1355.ECO26_3789,iECP_1309.ECP_2687,iECUMN_1333.ECUMN_3046,iETEC_1333.ETEC_2915,iEcDH1_1363.EcDH1_0965,iEcHS_1320.EcHS_A2860,iEcSMS35_1347.EcSMS35_2849,iEcolC_1368.EcolC_0988,iEcolC_1368.EcolC_1195,iHN637.CLJU_RS08480,iJO1366.b2724,iJR904.b2724,iSFV_1184.SFV_2779,iSSON_1240.SSON_2871,iUMNK88_1353.UMNK88_3076,iUMNK88_1353.UMNK88_3397,iY75_1357.Y75_RS14175,ic_1306.c3284	Fer4,Fer4_11,Fer4_20,Fer4_3,Fer4_4,Fer4_6,Fer4_7,Fer4_9,Pyr_redox_2
TLS3_k127_6746383_5	661367.LLO_2449	5.895e-11	63.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,1RNK9@1236|Gammaproteobacteria,1JCYR@118969|Legionellales	118969|Legionellales	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	hydG	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
TLS3_k127_6746562_11	869213.JCM21142_407	1.809e-51	187.0	COG1001@1|root,COG1001@2|Bacteria,4NFD9@976|Bacteroidetes,47KX0@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
TLS3_k127_6746562_1	1408473.JHXO01000001_gene2084	3.01e-237	751.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,2FNW9@200643|Bacteroidia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
TLS3_k127_6746562_12	332101.JIBU02000032_gene3049	8.731e-41	160.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia,36IP3@31979|Clostridiaceae	186801|Clostridia	S	IA, variant 3	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
TLS3_k127_6746562_3	1121904.ARBP01000012_gene1387	9.314e-178	567.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,47JHZ@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	-	-	-	-	-	-	-	-	-	-	PFK
TLS3_k127_6746562_16	1345023.M467_00645	3.155e-17	83.0	COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli	91061|Bacilli	S	Uncharacterized conserved protein (DUF2196)	ywbE	-	-	-	-	-	-	-	-	-	-	-	DUF2196
TLS3_k127_6746562_5	1158294.JOMI01000004_gene3543	1.254e-113	374.0	COG3386@1|root,COG3386@2|Bacteria,4NF4A@976|Bacteroidetes,2FSDK@200643|Bacteroidia	976|Bacteroidetes	G	SMP-30 Gluconolaconase LRE-like	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pectate_lyase_3,SGL
TLS3_k127_6746562_7	1168034.FH5T_21220	4.554e-98	329.0	COG0667@1|root,COG0667@2|Bacteria,4NP8D@976|Bacteroidetes,2FTGW@200643|Bacteroidia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_6746562_14	1121129.KB903373_gene459	3.844e-37	144.0	COG0824@1|root,COG0824@2|Bacteria,4NSJR@976|Bacteroidetes,2FS2E@200643|Bacteroidia,22Y6W@171551|Porphyromonadaceae	976|Bacteroidetes	S	acyl-CoA thioester hydrolase, YbgC YbaW family	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
TLS3_k127_6746562_15	1131462.DCF50_p1700	4.711e-19	94.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,24P0N@186801|Clostridia,2632C@186807|Peptococcaceae	186801|Clostridia	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
TLS3_k127_6746562_4	644282.Deba_2975	2.727e-116	389.0	COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,43CB2@68525|delta/epsilon subdivisions,2X7MH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_6746562_6	927658.AJUM01000037_gene1934	2.79e-113	379.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,2FMMI@200643|Bacteroidia,3XJ8F@558415|Marinilabiliaceae	976|Bacteroidetes	H	Polyprenyl synthetase	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
TLS3_k127_6746562_13	927658.AJUM01000037_gene1933	7.642e-38	145.0	COG0640@1|root,COG0640@2|Bacteria,4NSQD@976|Bacteroidetes,2FUJ6@200643|Bacteroidia,3XK8K@558415|Marinilabiliaceae	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
TLS3_k127_6746562_9	886379.AEWI01000119_gene595	5.347e-82	276.0	COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,2FS30@200643|Bacteroidia,3XJD6@558415|Marinilabiliaceae	976|Bacteroidetes	MU	Signal peptidase (SPase) II	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
TLS3_k127_6746562_10	313603.FB2170_10676	1.332e-56	207.0	2E10Y@1|root,32WGY@2|Bacteria,4NTDG@976|Bacteroidetes,1I7VE@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6746562_8	1168034.FH5T_05155	4.058e-89	310.0	COG3474@1|root,COG3474@2|Bacteria,4PKQA@976|Bacteroidetes	976|Bacteroidetes	C	Quinol cytochrome c oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
TLS3_k127_6746562_0	1168034.FH5T_05160	2.161e-307	970.0	COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes	976|Bacteroidetes	C	Quinol cytochrome c oxidoreductase	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
TLS3_k127_6746562_2	869213.JCM21142_266	4.784e-218	683.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,47K18@768503|Cytophagia	976|Bacteroidetes	C	PFAM Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
TLS3_k127_6773721_7	1487923.DP73_09795	2.758e-10	63.0	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes	1239|Firmicutes	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
TLS3_k127_6773721_6	1408473.JHXO01000006_gene1158	9.233e-19	89.0	COG2919@1|root,COG2919@2|Bacteria,4NURQ@976|Bacteroidetes,2FTC0@200643|Bacteroidia	976|Bacteroidetes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
TLS3_k127_6773721_1	313606.M23134_01237	3.81e-88	305.0	COG1215@1|root,COG1215@2|Bacteria,4NMSY@976|Bacteroidetes,47NMB@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_6773721_5	742725.HMPREF9450_01449	8.247e-38	149.0	COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes,2FPTR@200643|Bacteroidia	976|Bacteroidetes	M	membrane	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TLS3_k127_6773721_2	869213.JCM21142_104285	4.237e-74	260.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,47MUX@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_6773721_3	1168289.AJKI01000011_gene504	1.337e-61	229.0	COG3291@1|root,COG3291@2|Bacteria,4PHVT@976|Bacteroidetes,2FUHU@200643|Bacteroidia,3XIYY@558415|Marinilabiliaceae	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_6773721_4	929703.KE386491_gene2154	9.022e-42	160.0	COG1595@1|root,COG1595@2|Bacteria,4NQC9@976|Bacteroidetes,47QM4@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_6773721_0	1265505.ATUG01000002_gene1625	7.53e-102	337.0	COG0506@1|root,COG0506@2|Bacteria,1R8VR@1224|Proteobacteria,42P21@68525|delta/epsilon subdivisions,2WJU2@28221|Deltaproteobacteria,2MIBM@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
TLS3_k127_6807480_1	1408473.JHXO01000011_gene3107	2.151e-95	320.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
TLS3_k127_6807480_0	1313421.JHBV01000044_gene2919	1.511e-104	354.0	COG0457@1|root,COG0457@2|Bacteria,4NJEF@976|Bacteroidetes,1ITJC@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_16,TPR_2,TPR_8
TLS3_k127_6808762_0	709991.Odosp_3025	6.023e-163	518.0	COG1086@1|root,COG1086@2|Bacteria,4NGN2@976|Bacteroidetes,2FMXJ@200643|Bacteroidia,22W1Z@171551|Porphyromonadaceae	976|Bacteroidetes	M	Polysaccharide biosynthesis protein C-terminal	fnlA	-	5.1.3.2	ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00362	R00291	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Polysacc_syn_2C,Polysacc_synt_2
TLS3_k127_6808762_1	1500281.JQKZ01000002_gene1534	8.291e-98	332.0	COG1216@1|root,COG1216@2|Bacteria,4NNUD@976|Bacteroidetes,1I4ZX@117743|Flavobacteriia,3ZT3I@59732|Chryseobacterium	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_6808762_2	411477.PARMER_02835	1.351e-13	73.0	COG1216@1|root,COG1216@2|Bacteria,4NRTB@976|Bacteroidetes	976|Bacteroidetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6813186_0	1158294.JOMI01000007_gene99	0.0	1024.0	COG3408@1|root,COG3408@2|Bacteria,4NJY8@976|Bacteroidetes,2G2N9@200643|Bacteroidia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
TLS3_k127_6813186_2	1168034.FH5T_08895	9.814e-112	366.0	COG3828@1|root,COG3828@2|Bacteria,4NFYI@976|Bacteroidetes,2G2RZ@200643|Bacteroidia	976|Bacteroidetes	CG	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	CARDB,Copper-bind,ThuA
TLS3_k127_6813186_1	886379.AEWI01000001_gene1840	0.0	1018.0	28I5V@1|root,2Z891@2|Bacteria,4NF4U@976|Bacteroidetes,2FPB8@200643|Bacteroidia,3XIWU@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 9	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9
TLS3_k127_6813678_9	1341181.FLJC2902T_05050	5.705e-13	70.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1I54R@117743|Flavobacteriia,2NXH2@237|Flavobacterium	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
TLS3_k127_6813678_1	1047013.AQSP01000029_gene2170	7.396e-213	673.0	COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
TLS3_k127_6813678_5	1047013.AQSP01000139_gene2340	1.045e-80	281.0	COG1975@1|root,COG1975@2|Bacteria,2NPTS@2323|unclassified Bacteria	2|Bacteria	O	XdhC and CoxI family	pucA	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
TLS3_k127_6813678_8	1047013.AQSP01000139_gene2341	3.221e-38	151.0	COG2068@1|root,COG2068@2|Bacteria,2NPK5@2323|unclassified Bacteria	2|Bacteria	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	mocA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061602,GO:0070567,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902759,GO:1902760	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_3649,iB21_1397.B21_02672,iECABU_c1320.ECABU_c31580,iECBD_1354.ECBD_0860,iECB_1328.ECB_02710,iECD_1391.ECD_02710,iEcHS_1320.EcHS_A3037	HD,HTH_1,NTP_transf_3
TLS3_k127_6813678_6	1168034.FH5T_11985	6.962e-66	228.0	COG2080@1|root,COG2080@2|Bacteria,4PNKJ@976|Bacteroidetes	976|Bacteroidetes	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
TLS3_k127_6813678_0	1168034.FH5T_11980	3.098e-245	777.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
TLS3_k127_6813678_7	927658.AJUM01000047_gene2819	3.282e-53	192.0	COG3295@1|root,COG3295@2|Bacteria,4NNGT@976|Bacteroidetes,2FNIB@200643|Bacteroidia,3XKEK@558415|Marinilabiliaceae	976|Bacteroidetes	S	Putative PepSY_TM-like	-	-	-	ko:K09939	-	-	-	-	ko00000	-	-	-	PepSY_TM_like_2
TLS3_k127_6813678_10	742767.HMPREF9456_02645	4.744e-10	66.0	29TPU@1|root,30EXX@2|Bacteria,4NPRV@976|Bacteroidetes,2FNJR@200643|Bacteroidia,22XYQ@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6813678_2	388413.ALPR1_19928	5.143e-192	611.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,47JNX@768503|Cytophagia	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_6813678_4	234267.Acid_3245	2.679e-91	308.0	COG1082@1|root,COG1082@2|Bacteria,3Y73B@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_6813678_3	504472.Slin_3895	2.816e-150	484.0	COG1312@1|root,COG1312@2|Bacteria,4NF30@976|Bacteroidetes,47N1H@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the dehydration of D-mannonate	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
TLS3_k127_6816894_1	925409.KI911562_gene1598	9.474e-180	570.0	COG2211@1|root,COG2211@2|Bacteria,4NE0X@976|Bacteroidetes,1J0SK@117747|Sphingobacteriia	976|Bacteroidetes	G	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
TLS3_k127_6816894_0	1168034.FH5T_17265	0.0	1283.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FW4E@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_6816894_3	1168034.FH5T_17260	2.652e-77	282.0	COG1435@1|root,COG1435@2|Bacteria,4NE0A@976|Bacteroidetes,2FN01@200643|Bacteroidia	976|Bacteroidetes	F	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_6816894_2	1168034.FH5T_17255	2.226e-126	426.0	COG1435@1|root,COG1435@2|Bacteria,4NE0A@976|Bacteroidetes,2FN01@200643|Bacteroidia	976|Bacteroidetes	F	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_6816894_6	1168034.FH5T_17245	4.329e-33	134.0	28KYZ@1|root,2ZAEB@2|Bacteria,4NHBZ@976|Bacteroidetes,2FP4X@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6816894_4	1168034.FH5T_17245	1.821e-75	269.0	28KYZ@1|root,2ZAEB@2|Bacteria,4NHBZ@976|Bacteroidetes,2FP4X@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6816894_5	1123008.KB905708_gene1024	8.76e-37	142.0	COG0673@1|root,COG0673@2|Bacteria,4NF9M@976|Bacteroidetes,2FP2F@200643|Bacteroidia,22ZHX@171551|Porphyromonadaceae	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
TLS3_k127_6821313_2	1128421.JAGA01000002_gene1294	1.64e-31	126.0	COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria	2|Bacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
TLS3_k127_6821313_4	1279009.ADICEAN_03716	5.561e-13	73.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,47MA1@768503|Cytophagia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_6821313_1	643867.Ftrac_1450	1.418e-91	314.0	COG0204@1|root,COG0204@2|Bacteria,4NGR9@976|Bacteroidetes,47K88@768503|Cytophagia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TLS3_k127_6821313_0	153721.MYP_4273	1.52e-147	481.0	COG1233@1|root,COG1233@2|Bacteria,4NG5Y@976|Bacteroidetes,47K5X@768503|Cytophagia	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.23	ko:K09516	ko00830,map00830	-	R07163	RC01835	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
TLS3_k127_6821313_3	153721.MYP_186	7.778e-26	111.0	COG3049@1|root,COG3049@2|Bacteria,4PKMY@976|Bacteroidetes,47MVG@768503|Cytophagia	976|Bacteroidetes	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
TLS3_k127_6834811_0	927658.AJUM01000010_gene1347	2.45e-187	595.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,2FMED@200643|Bacteroidia,3XIP6@558415|Marinilabiliaceae	976|Bacteroidetes	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
TLS3_k127_6834811_2	926549.KI421517_gene1620	4.858e-38	148.0	28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,47M02@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6834811_1	742726.HMPREF9448_00793	6.023e-159	510.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,22VY5@171551|Porphyromonadaceae	976|Bacteroidetes	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_6866956_0	1501391.LG35_08285	7.434e-256	800.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,2FN1R@200643|Bacteroidia,22U0K@171550|Rikenellaceae	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
TLS3_k127_6866956_1	1122226.AUHX01000003_gene75	2.009e-57	212.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,1HX46@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase, M23	mepM_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_6875631_1	1189612.A33Q_4118	1.398e-50	189.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,47K59@768503|Cytophagia	976|Bacteroidetes	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
TLS3_k127_6875631_0	1168289.AJKI01000003_gene2736	1.022e-107	366.0	COG1470@1|root,COG1470@2|Bacteria,4NGFF@976|Bacteroidetes,2FN5A@200643|Bacteroidia,3XJ0Y@558415|Marinilabiliaceae	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_6875631_2	1089547.KB913013_gene1125	1.51e-40	156.0	COG1595@1|root,COG1595@2|Bacteria,4NNBY@976|Bacteroidetes,47PH5@768503|Cytophagia	976|Bacteroidetes	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_6875631_3	1168034.FH5T_07755	2.729e-33	141.0	COG3712@1|root,COG3712@2|Bacteria,4NICU@976|Bacteroidetes,2FPP5@200643|Bacteroidia	976|Bacteroidetes	PT	Sigma factor regulatory protein, FecR PupR family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
TLS3_k127_6875631_4	457424.BFAG_01244	4.096e-26	117.0	COG1470@1|root,COG1470@2|Bacteria,4NQ03@976|Bacteroidetes,2G2PI@200643|Bacteroidia,4AW2B@815|Bacteroidaceae	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_689137_0	927658.AJUM01000047_gene2778	1.487e-191	644.0	28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,2G1ZT@200643|Bacteroidia,3XIMW@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6893090_2	468059.AUHA01000002_gene871	1.794e-19	101.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1J0HF@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
TLS3_k127_6893090_1	411477.PARMER_00404	7.396e-97	330.0	COG1409@1|root,COG1409@2|Bacteria,4NG8Q@976|Bacteroidetes,2G35U@200643|Bacteroidia,22ZKG@171551|Porphyromonadaceae	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
TLS3_k127_6893090_0	1150600.ADIARSV_3341	2.253e-209	666.0	COG1435@1|root,COG1435@2|Bacteria,4NE0A@976|Bacteroidetes,1INRJ@117747|Sphingobacteriia	976|Bacteroidetes	F	PFAM RagB SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_6894601_0	1499967.BAYZ01000016_gene6552	2.298e-121	399.0	COG0855@1|root,COG0855@2|Bacteria	2|Bacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006091,GO:0006139,GO:0006163,GO:0006165,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006757,GO:0006793,GO:0006796,GO:0006797,GO:0006799,GO:0006807,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009279,GO:0009358,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016778,GO:0017144,GO:0019538,GO:0019637,GO:0019693,GO:0019867,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0032991,GO:0034641,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043751,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044425,GO:0044462,GO:0044464,GO:0046031,GO:0046034,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0061695,GO:0071704,GO:0071944,GO:0072521,GO:0098552,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1902494,GO:1990234	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	iSbBS512_1146.SbBS512_E2875	PP_kinase,PP_kinase_C,PP_kinase_N
TLS3_k127_6894601_2	1408473.JHXO01000001_gene2326	6.206e-27	115.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX,Rieske
TLS3_k127_6894601_1	869213.JCM21142_52362	1.407e-69	240.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,47P7U@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
TLS3_k127_6894601_3	869213.JCM21142_104243	7.58e-18	87.0	COG2340@1|root,COG2340@2|Bacteria,4P06D@976|Bacteroidetes	976|Bacteroidetes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
TLS3_k127_6903401_1	385682.AFSL01000044_gene355	4.361e-131	428.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,2FM68@200643|Bacteroidia,3XJB5@558415|Marinilabiliaceae	976|Bacteroidetes	P	Polyphosphate kinase middle domain	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
TLS3_k127_6903401_2	945713.IALB_1794	2.096e-27	118.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
TLS3_k127_6903401_0	869213.JCM21142_52203	2.954e-149	479.0	COG0205@1|root,COG0205@2|Bacteria,4NGN7@976|Bacteroidetes,47TRF@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
TLS3_k127_6903401_4	1156937.MFUM_220012	1.419e-07	63.0	COG5607@1|root,COG5607@2|Bacteria,46WNV@74201|Verrucomicrobia,37H27@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
TLS3_k127_6903401_3	1408473.JHXO01000010_gene3625	1.219e-13	72.0	COG0243@1|root,COG0243@2|Bacteria,4NITD@976|Bacteroidetes	976|Bacteroidetes	C	Molybdopterin oxidoreductase	-	-	1.7.2.3,1.8.5.5	ko:K07812,ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.4,5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
TLS3_k127_6905513_1	1121904.ARBP01000026_gene694	2.631e-182	577.0	COG0673@1|root,COG0673@2|Bacteria,4NJ92@976|Bacteroidetes,47MAS@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_6905513_0	694427.Palpr_1307	2.272e-232	728.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,2FMHE@200643|Bacteroidia,22W0Y@171551|Porphyromonadaceae	976|Bacteroidetes	O	magnesium chelatase	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
TLS3_k127_6905513_3	468059.AUHA01000002_gene1098	3.267e-75	257.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,1IQEI@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
TLS3_k127_6905513_2	1347342.BN863_10230	7.708e-157	507.0	COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,1HY05@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-glucosidase	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
TLS3_k127_6914460_0	1499967.BAYZ01000028_gene1265	9.351e-146	472.0	COG1509@1|root,COG1509@2|Bacteria,2NNY6@2323|unclassified Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	kamA	-	5.4.3.2	ko:K01843,ko:K19810	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000,ko03012	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
TLS3_k127_6914460_1	1121440.AUMA01000005_gene2642	1.49e-81	280.0	COG1181@1|root,COG1181@2|Bacteria,1MX3I@1224|Proteobacteria,42SA1@68525|delta/epsilon subdivisions,2WNIR@28221|Deltaproteobacteria,2M8FI@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
TLS3_k127_6915303_1	385682.AFSL01000003_gene1886	1.69e-74	257.0	COG0167@1|root,COG0167@2|Bacteria,4NF4D@976|Bacteroidetes,2FM0X@200643|Bacteroidia,3XISP@558415|Marinilabiliaceae	976|Bacteroidetes	F	Dihydroorotate dehydrogenase	preA	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
TLS3_k127_6915303_4	1408473.JHXO01000004_gene133	3.464e-09	64.0	2EQMK@1|root,33I7I@2|Bacteria,4NY3R@976|Bacteroidetes,2FVUP@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6915303_2	869213.JCM21142_3966	2.861e-70	248.0	29N3N@1|root,3091D@2|Bacteria,4NNZB@976|Bacteroidetes,47PVZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6915303_3	869213.JCM21142_3965	1.14e-31	128.0	2DXS6@1|root,34692@2|Bacteria,4P5EX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6915303_0	1408473.JHXO01000004_gene131	0.0	1217.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,2FNFZ@200643|Bacteroidia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
TLS3_k127_6918711_1	1408473.JHXO01000010_gene3689	2.238e-99	339.0	COG0038@1|root,COG0038@2|Bacteria,4NZYS@976|Bacteroidetes,2G0DB@200643|Bacteroidia	976|Bacteroidetes	P	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
TLS3_k127_6918711_2	1235803.C825_01795	2.288e-43	165.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,2FMF7@200643|Bacteroidia,22XKK@171551|Porphyromonadaceae	976|Bacteroidetes	G	polysaccharide deacetylase	pgdA_1	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
TLS3_k127_6918711_0	886379.AEWI01000012_gene1170	3.377e-167	535.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,2FN59@200643|Bacteroidia,3XJVD@558415|Marinilabiliaceae	976|Bacteroidetes	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
TLS3_k127_6927869_0	861299.J421_0703	4.537e-176	567.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Sulfatase
TLS3_k127_6927869_1	761193.Runsl_0692	3.404e-89	298.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,47JKY@768503|Cytophagia	976|Bacteroidetes	P	C-terminal region of aryl-sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
TLS3_k127_6935208_2	1408473.JHXO01000011_gene3005	4.472e-56	203.0	COG1807@1|root,COG1807@2|Bacteria,4NHXW@976|Bacteroidetes,2FY7X@200643|Bacteroidia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_6935208_0	616991.JPOO01000001_gene2786	3.03e-175	560.0	COG4225@1|root,COG4225@2|Bacteria,4NH7G@976|Bacteroidetes,1HZNV@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl Hydrolase Family 88	yteR_9	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88,Lipase_GDSL_2
TLS3_k127_6935208_1	925409.KI911562_gene2446	1.658e-82	278.0	COG3250@1|root,COG3250@2|Bacteria,4NF4T@976|Bacteroidetes,1IVA8@117747|Sphingobacteriia	976|Bacteroidetes	G	Beta galactosidase small chain	-	-	-	-	-	-	-	-	-	-	-	-	Bgal_small_N,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
TLS3_k127_6942731_2	690850.Desaf_0098	1.145e-91	311.0	COG0859@1|root,COG0859@2|Bacteria,1QUID@1224|Proteobacteria,43D98@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,Methyltransf_23
TLS3_k127_6942731_1	365046.Rta_16060	1.67e-157	499.0	COG0451@1|root,COG0451@2|Bacteria,1Q4V9@1224|Proteobacteria,2VZIW@28216|Betaproteobacteria,4AGVJ@80864|Comamonadaceae	28216|Betaproteobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6942731_0	1124780.ANNU01000044_gene544	4.377e-162	525.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,4NFT6@976|Bacteroidetes,47K86@768503|Cytophagia	976|Bacteroidetes	CE	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
TLS3_k127_6942731_3	1232437.KL661961_gene3053	2.1e-47	178.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N38@68525|delta/epsilon subdivisions,2WK56@28221|Deltaproteobacteria,2MHP9@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Di-haem cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Cytochrom_C
TLS3_k127_6942731_5	398512.JQKC01000032_gene4480	3.397e-45	183.0	COG5305@1|root,COG5305@2|Bacteria,1UXXF@1239|Firmicutes,249M9@186801|Clostridia,3WGH7@541000|Ruminococcaceae	186801|Clostridia	P	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,DUF2141,PMT_2
TLS3_k127_6942731_4	1123008.KB905694_gene1558	3.088e-47	171.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_6954282_3	313603.FB2170_17356	1.41e-47	186.0	COG2234@1|root,COG2234@2|Bacteria,4NEHY@976|Bacteroidetes,1HYWG@117743|Flavobacteriia,2PGNH@252356|Maribacter	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
TLS3_k127_6954282_0	1307761.L21SP2_2449	3.707e-154	497.0	COG0492@1|root,COG0492@2|Bacteria,2J7WA@203691|Spirochaetes	203691|Spirochaetes	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_6954282_2	1168034.FH5T_05705	7.785e-51	183.0	COG3118@1|root,COG3118@2|Bacteria,4NQNX@976|Bacteroidetes,2FSPP@200643|Bacteroidia	976|Bacteroidetes	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
TLS3_k127_6954282_1	1307761.L21SP2_2450	4.457e-74	253.0	COG0641@1|root,COG0641@2|Bacteria,2JB1P@203691|Spirochaetes	203691|Spirochaetes	C	4Fe-4S single cluster domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12
TLS3_k127_6956657_0	1442599.JAAN01000043_gene450	1.456e-134	440.0	COG2271@1|root,COG2271@2|Bacteria,1MV04@1224|Proteobacteria,1RP70@1236|Gammaproteobacteria,1X56Y@135614|Xanthomonadales	135614|Xanthomonadales	G	Major facilitator superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
TLS3_k127_6956657_2	1185876.BN8_02134	2.411e-90	305.0	COG1082@1|root,COG1082@2|Bacteria,4NIWS@976|Bacteroidetes,47K4W@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
TLS3_k127_6956657_1	761193.Runsl_3310	4.616e-130	432.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_6956657_3	694427.Palpr_1009	8.954e-20	95.0	COG1629@1|root,COG4771@2|Bacteria,4PNTQ@976|Bacteroidetes,2G0Y7@200643|Bacteroidia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
TLS3_k127_6987717_1	929703.KE386491_gene547	1.161e-127	413.0	COG0627@1|root,COG0627@2|Bacteria,4NGI8@976|Bacteroidetes,47M5Z@768503|Cytophagia	976|Bacteroidetes	S	Putative esterase	xynZ	-	-	-	-	-	-	-	-	-	-	-	Esterase
TLS3_k127_6987717_2	1296415.JACC01000006_gene1543	1.525e-84	295.0	COG1502@1|root,COG1502@2|Bacteria,4NE2W@976|Bacteroidetes,1HWU9@117743|Flavobacteriia,2YI02@290174|Aquimarina	976|Bacteroidetes	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
TLS3_k127_6987717_0	435591.BDI_3581	1.243e-128	423.0	COG0823@1|root,COG0823@2|Bacteria,4NGH4@976|Bacteroidetes,2FN8G@200643|Bacteroidia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_7009383_0	385682.AFSL01000019_gene2201	8.424e-212	666.0	COG0701@1|root,COG0701@2|Bacteria,4NJME@976|Bacteroidetes,2FQNA@200643|Bacteroidia,3XJWS@558415|Marinilabiliaceae	976|Bacteroidetes	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
TLS3_k127_7009383_2	945713.IALB_2824	4.485e-42	158.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	resA	-	-	ko:K02199,ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	AhpC-TSA,Redoxin,Thioredoxin
TLS3_k127_7009383_1	1168034.FH5T_14830	1.177e-70	246.0	COG0345@1|root,COG0345@2|Bacteria	2|Bacteria	E	pyrroline-5-carboxylate reductase activity	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
TLS3_k127_7013310_5	1121129.KB903359_gene1235	3.315e-09	59.0	COG0058@1|root,COG0297@1|root,COG0058@2|Bacteria,COG0297@2|Bacteria,4NGR1@976|Bacteroidetes,2FNN5@200643|Bacteroidia,22WPC@171551|Porphyromonadaceae	976|Bacteroidetes	G	alpha-glucan phosphorylase	glgP	-	2.4.1.1,2.4.1.11,2.4.1.8	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R00292,R01555,R02111	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GH65,GT3,GT35	-	DUF3417,Glycogen_syn,Phosphorylase
TLS3_k127_7013310_0	203275.BFO_0816	1.231e-272	856.0	COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes,2FMTG@200643|Bacteroidia,22W4H@171551|Porphyromonadaceae	976|Bacteroidetes	G	1,4-alpha-glucan branching enzyme	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
TLS3_k127_7013310_2	1168034.FH5T_11385	1.869e-74	261.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,2FM7A@200643|Bacteroidia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
TLS3_k127_7013310_1	742767.HMPREF9456_00506	1.958e-252	784.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,2FPWZ@200643|Bacteroidia,22W9Y@171551|Porphyromonadaceae	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
TLS3_k127_7013310_6	1453500.AT05_08785	1.098e-06	57.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Rieske
TLS3_k127_7013310_3	927658.AJUM01000037_gene2231	4.757e-60	211.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,2FPFU@200643|Bacteroidia,3XJU5@558415|Marinilabiliaceae	976|Bacteroidetes	K	Transcription elongation factor, N-terminal	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
TLS3_k127_7013310_4	929703.KE386491_gene2606	1.567e-55	197.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,47Q95@768503|Cytophagia	976|Bacteroidetes	FG	HIT family hydrolase	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
TLS3_k127_7016615_1	927658.AJUM01000034_gene48	1.771e-54	193.0	COG3682@1|root,COG3682@2|Bacteria,4NNVM@976|Bacteroidetes,2FV5R@200643|Bacteroidia,3XK7S@558415|Marinilabiliaceae	976|Bacteroidetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
TLS3_k127_7016615_0	927658.AJUM01000034_gene47	7.125e-97	343.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,2FNCU@200643|Bacteroidia,3XJ48@558415|Marinilabiliaceae	976|Bacteroidetes	KMT	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
TLS3_k127_7016615_4	1408473.JHXO01000012_gene412	6.988e-38	157.0	29XIH@1|root,30J9E@2|Bacteria,4PA1B@976|Bacteroidetes,2FVYM@200643|Bacteroidia	976|Bacteroidetes	S	6-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128
TLS3_k127_7016615_2	237368.SCABRO_03051	6.816e-49	179.0	COG1943@1|root,COG1943@2|Bacteria,2J0GJ@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
TLS3_k127_7016615_3	385682.AFSL01000040_gene270	6.775e-45	169.0	COG3291@1|root,COG3291@2|Bacteria,4PHVT@976|Bacteroidetes,2FUHU@200643|Bacteroidia,3XIYY@558415|Marinilabiliaceae	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_703174_3	1280674.AUJK01000006_gene1892	1.211e-42	160.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,2FS1V@200643|Bacteroidia	976|Bacteroidetes	S	Hydrolase, P-loop family	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
TLS3_k127_703174_0	714943.Mucpa_2744	5.068e-189	603.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,1IP34@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
TLS3_k127_703174_1	1168034.FH5T_08815	1.727e-148	502.0	COG1729@1|root,COG1729@2|Bacteria,4PKGA@976|Bacteroidetes,2G3G6@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
TLS3_k127_703174_4	927658.AJUM01000034_gene281	4.388e-25	106.0	COG0694@1|root,COG0694@2|Bacteria,4NSHJ@976|Bacteroidetes,2G28J@200643|Bacteroidia,3XKCM@558415|Marinilabiliaceae	976|Bacteroidetes	O	NifU-like domain	nfuA	-	-	-	-	-	-	-	-	-	-	-	NifU
TLS3_k127_703174_2	1121097.JCM15093_2056	3.52e-43	160.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,2FKYK@200643|Bacteroidia,4AK6W@815|Bacteroidaceae	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
TLS3_k127_7032131_2	426355.Mrad2831_4674	1.639e-05	54.0	2DEHC@1|root,2ZN03@2|Bacteria,1P9RK@1224|Proteobacteria,2UX5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7032131_1	1122931.AUAE01000005_gene3324	3.088e-08	57.0	2DR77@1|root,33AIC@2|Bacteria,4NZS2@976|Bacteroidetes,2G1QG@200643|Bacteroidia,2310T@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7032131_0	746697.Aeqsu_2564	0.0	1018.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_7056679_4	269798.CHU_1022	2.874e-15	87.0	COG0664@1|root,COG1413@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,4PKPI@976|Bacteroidetes,47NQS@768503|Cytophagia	976|Bacteroidetes	C	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,cNMP_binding
TLS3_k127_7056679_1	269798.CHU_1024	1.215e-153	524.0	COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,4NEYQ@976|Bacteroidetes,47NKP@768503|Cytophagia	976|Bacteroidetes	M	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
TLS3_k127_7056679_0	1168289.AJKI01000041_gene3328	5.862e-229	719.0	COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,2FMVJ@200643|Bacteroidia,3XIYH@558415|Marinilabiliaceae	976|Bacteroidetes	G	BPG-independent PGAM N-terminus (iPGM_N)	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
TLS3_k127_7056679_3	1121129.KB903360_gene3101	1.3e-57	205.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,2FNXY@200643|Bacteroidia,22XM5@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
TLS3_k127_7056679_2	435591.BDI_0500	4.33e-129	420.0	COG1629@1|root,COG3188@1|root,COG1629@2|Bacteria,COG3188@2|Bacteria,4PKAS@976|Bacteroidetes,2FWM7@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_7065822_1	1122176.KB903576_gene5048	4.204e-42	163.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia	976|Bacteroidetes	V	TIGRFAM Acidobacterial duplicated orphan permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_7065822_2	1123058.KB894234_gene1527	0.0008989	42.0	2BBPA@1|root,3257C@2|Bacteria,4NRAR@976|Bacteroidetes,1I30Z@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3575
TLS3_k127_7065822_0	1123057.P872_16485	9.994e-210	667.0	COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,4PKNJ@976|Bacteroidetes,47JHY@768503|Cytophagia	976|Bacteroidetes	NT	protein-glutamate methylesterase	-	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF_2,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9
TLS3_k127_7068109_3	927658.AJUM01000024_gene2541	3.424e-124	406.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,3XJ8Y@558415|Marinilabiliaceae	976|Bacteroidetes	J	Polyribonucleotide nucleotidyltransferase, RNA binding domain	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
TLS3_k127_7068109_4	1408473.JHXO01000006_gene1051	3.772e-78	266.0	COG1428@1|root,COG1428@2|Bacteria,4PM5R@976|Bacteroidetes	976|Bacteroidetes	F	deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
TLS3_k127_7068109_2	869213.JCM21142_72668	2.461e-163	532.0	COG5010@1|root,COG5010@2|Bacteria,4PMJW@976|Bacteroidetes	976|Bacteroidetes	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
TLS3_k127_7068109_5	1121129.KB903359_gene1937	3.562e-61	216.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,2FS50@200643|Bacteroidia,22XKS@171551|Porphyromonadaceae	976|Bacteroidetes	J	RNA methyltransferase	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
TLS3_k127_7068109_1	385682.AFSL01000062_gene1610	1.148e-172	550.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,2FNFG@200643|Bacteroidia,3XINA@558415|Marinilabiliaceae	976|Bacteroidetes	C	ATP-grasp domain	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
TLS3_k127_7068109_7	929562.Emtol_2389	9.319e-12	66.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,4NVG3@976|Bacteroidetes,47QRI@768503|Cytophagia	976|Bacteroidetes	S	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
TLS3_k127_7068109_6	1121904.ARBP01000012_gene1285	1.818e-31	129.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,4NVG3@976|Bacteroidetes,47QRI@768503|Cytophagia	976|Bacteroidetes	S	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
TLS3_k127_7068109_0	585543.HMPREF0969_01333	1.704e-228	730.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,2FN6Z@200643|Bacteroidia,4AM5E@815|Bacteroidaceae	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
TLS3_k127_7075983_0	1408473.JHXO01000012_gene317	1.3e-108	357.0	COG0842@1|root,COG0842@2|Bacteria,4NKB0@976|Bacteroidetes,2FW5E@200643|Bacteroidia	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
TLS3_k127_7075983_2	391603.FBALC1_06073	5.372e-38	152.0	COG3595@1|root,COG3595@2|Bacteria,4NIA2@976|Bacteroidetes,1I0CY@117743|Flavobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
TLS3_k127_7075983_1	886379.AEWI01000007_gene836	1.566e-104	347.0	COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia,3XIZU@558415|Marinilabiliaceae	976|Bacteroidetes	G	Phosphoglucose isomerase	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
TLS3_k127_7083094_0	1300143.CCAV010000002_gene482	1.216e-302	942.0	COG0620@1|root,COG0620@2|Bacteria,4NF5S@976|Bacteroidetes,1HY90@117743|Flavobacteriia,3ZPF8@59732|Chryseobacterium	976|Bacteroidetes	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
TLS3_k127_7083094_3	485913.Krac_5920	3.991e-150	488.0	COG0641@1|root,COG0641@2|Bacteria,2G74V@200795|Chloroflexi	200795|Chloroflexi	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Radical_SAM,SPASM
TLS3_k127_7083094_2	1168034.FH5T_04375	6.112e-213	672.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,2FMAW@200643|Bacteroidia	976|Bacteroidetes	P	Arylsulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TLS3_k127_7083094_4	604354.TSIB_0629	1.567e-74	259.0	COG1180@1|root,arCOG00952@2157|Archaea,2XZW0@28890|Euryarchaeota,244ZY@183968|Thermococci	183968|Thermococci	C	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
TLS3_k127_7083094_1	641107.CDLVIII_0595	3.151e-245	773.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,36EFE@31979|Clostridiaceae	186801|Clostridia	C	Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
TLS3_k127_7087158_0	641524.ADICYQ_0052	2.064e-216	683.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,47N97@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TLS3_k127_7087158_5	760192.Halhy_6309	1.498e-109	383.0	COG4206@1|root,COG4206@2|Bacteria,4NIJS@976|Bacteroidetes	976|Bacteroidetes	H	COG4206 Outer membrane cobalamin receptor protein	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_7087158_2	1408473.JHXO01000009_gene3466	1.353e-163	526.0	COG1082@1|root,COG2152@1|root,COG1082@2|Bacteria,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes,2FP8T@200643|Bacteroidia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_7087158_4	869213.JCM21142_41985	4.637e-142	460.0	COG3507@1|root,COG3507@2|Bacteria,4PKZY@976|Bacteroidetes,47KV1@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
TLS3_k127_7087158_7	1408473.JHXO01000013_gene496	4.433e-82	280.0	COG4225@1|root,COG4225@2|Bacteria,4NFWI@976|Bacteroidetes	976|Bacteroidetes	V	Glycosyl Hydrolase Family 88	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7087158_1	761193.Runsl_2137	1.361e-171	546.0	COG4225@1|root,COG4225@2|Bacteria,4NHK2@976|Bacteroidetes,47KS0@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl Hydrolase Family 88	yteR_10	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
TLS3_k127_7087158_3	1123278.KB893422_gene1617	1.616e-145	472.0	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,47M6K@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_7087158_8	1041826.FCOL_09620	1.222e-77	268.0	COG0300@1|root,COG0300@2|Bacteria,4NKNE@976|Bacteroidetes,1IMIN@117743|Flavobacteriia,2NTWH@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
TLS3_k127_7087158_6	313603.FB2170_14243	9.099e-89	306.0	COG2207@1|root,COG2207@2|Bacteria,4NKIX@976|Bacteroidetes,1I0WH@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_7108607_6	1219084.AP014508_gene830	6.729e-110	361.0	COG3959@1|root,COG3959@2|Bacteria,2GCXS@200918|Thermotogae	200918|Thermotogae	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
TLS3_k127_7108607_5	435590.BVU_0358	4.04e-132	427.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,2FQ5P@200643|Bacteroidia,4AKNM@815|Bacteroidaceae	976|Bacteroidetes	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
TLS3_k127_7108607_1	694427.Palpr_0670	4.649e-250	781.0	COG5512@1|root,COG5512@2|Bacteria,4NHWD@976|Bacteroidetes,2FP0N@200643|Bacteroidia,22Z4E@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
TLS3_k127_7108607_3	1408473.JHXO01000013_gene504	2.561e-187	597.0	COG0554@1|root,COG0554@2|Bacteria,4NFUH@976|Bacteroidetes,2G32Z@200643|Bacteroidia	976|Bacteroidetes	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
TLS3_k127_7108607_2	1408473.JHXO01000013_gene505	2.338e-215	677.0	COG2407@1|root,COG2407@2|Bacteria,4NFGS@976|Bacteroidetes,2FMDZ@200643|Bacteroidia	976|Bacteroidetes	G	L-fucose isomerase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
TLS3_k127_7108607_4	761193.Runsl_1271	5.732e-141	461.0	COG0673@1|root,COG0673@2|Bacteria,4NGPP@976|Bacteroidetes,47N04@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
TLS3_k127_7108607_7	1121904.ARBP01000011_gene1485	4.877e-51	192.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,47NJ6@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_7108607_0	435591.BDI_3296	5.832e-255	802.0	COG3250@1|root,COG3250@2|Bacteria,4NHRH@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	lacZ_17	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
TLS3_k127_7121698_3	880073.Calab_3421	4.207e-06	49.0	COG0076@1|root,COG0076@2|Bacteria,2NQW3@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-dependent decarboxylase conserved domain	ddc	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
TLS3_k127_7121698_1	1408473.JHXO01000007_gene843	5.809e-150	509.0	COG0823@1|root,COG0823@2|Bacteria,4NGPR@976|Bacteroidetes,2FNGJ@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7121698_0	1168034.FH5T_10135	7.18e-321	1013.0	COG0038@1|root,COG0038@2|Bacteria,4NZYS@976|Bacteroidetes,2G0DB@200643|Bacteroidia	976|Bacteroidetes	P	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
TLS3_k127_7121698_2	251221.35212249	2.421e-13	75.0	COG0745@1|root,COG0745@2|Bacteria,1G6W5@1117|Cyanobacteria	1117|Cyanobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_7122507_2	694427.Palpr_1909	1.997e-29	122.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,2FSN9@200643|Bacteroidia,22YE3@171551|Porphyromonadaceae	976|Bacteroidetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
TLS3_k127_7122507_0	435591.BDI_2912	2.067e-152	491.0	COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,2FPW0@200643|Bacteroidia,22WUF@171551|Porphyromonadaceae	976|Bacteroidetes	E	Papain family cysteine protease	-	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1,Peptidase_C1_2
TLS3_k127_7122507_3	1237149.C900_04906	2.049e-28	116.0	2AFHA@1|root,315HT@2|Bacteria,4NQ5F@976|Bacteroidetes,47VEE@768503|Cytophagia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
TLS3_k127_7122507_1	1121011.AUCB01000036_gene814	5.843e-111	367.0	COG0318@1|root,COG0318@2|Bacteria,4NDXK@976|Bacteroidetes,1IJB2@117743|Flavobacteriia,23FWU@178469|Arenibacter	976|Bacteroidetes	IQ	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
TLS3_k127_7133212_1	1168034.FH5T_00630	9.499e-241	753.0	COG1069@1|root,COG1069@2|Bacteria,4NEFQ@976|Bacteroidetes,2FNNI@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
TLS3_k127_7133212_3	1047013.AQSP01000144_gene926	2.358e-208	660.0	COG3534@1|root,COG3534@2|Bacteria,2NQS6@2323|unclassified Bacteria	2|Bacteria	G	Alpha-L-arabinofuranosidase C-terminus	abfA	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
TLS3_k127_7133212_0	761193.Runsl_5038	1.614e-308	965.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,47M6F@768503|Cytophagia	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	F5_F8_type_C,Glyco_hydro_127
TLS3_k127_7133212_4	1121097.JCM15093_1927	9.399e-97	332.0	COG1649@1|root,COG1649@2|Bacteria,4NJ45@976|Bacteroidetes,2FMC1@200643|Bacteroidia,4AKDR@815|Bacteroidaceae	976|Bacteroidetes	G	COG NOG04984 non supervised orthologous group	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
TLS3_k127_7133212_5	742725.HMPREF9450_01036	7.643e-53	205.0	COG1874@1|root,COG1874@2|Bacteria,4PC2I@976|Bacteroidetes,2FZW2@200643|Bacteroidia	976|Bacteroidetes	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
TLS3_k127_7133212_2	1288963.ADIS_4381	5.583e-233	730.0	COG5512@1|root,COG5512@2|Bacteria,4NHWD@976|Bacteroidetes,47N4B@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
TLS3_k127_7139731_3	1168034.FH5T_01530	2.399e-72	253.0	COG1520@1|root,COG1520@2|Bacteria,4P310@976|Bacteroidetes	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
TLS3_k127_7139731_4	1168034.FH5T_01535	4.224e-52	197.0	COG0493@1|root,COG0493@2|Bacteria,4P2CU@976|Bacteroidetes,2FXPN@200643|Bacteroidia	976|Bacteroidetes	E	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_20
TLS3_k127_7139731_0	69014.TK1613	3.58e-203	658.0	COG1894@1|root,COG4231@1|root,arCOG01609@2157|Archaea,arCOG04537@2157|Archaea,2XUYN@28890|Euryarchaeota,243V2@183968|Thermococci	183968|Thermococci	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
TLS3_k127_7139731_1	1168034.FH5T_01550	2.134e-118	401.0	COG1520@1|root,COG1520@2|Bacteria,4P1VG@976|Bacteroidetes,2FW8D@200643|Bacteroidia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TLS3_k127_7139731_2	1168034.FH5T_01555	9.711e-77	266.0	COG0348@1|root,COG0348@2|Bacteria,4NPVD@976|Bacteroidetes,2FTEY@200643|Bacteroidia	976|Bacteroidetes	C	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
TLS3_k127_7140135_0	886379.AEWI01000035_gene3048	0.0	1110.0	COG0574@1|root,COG0745@1|root,COG0574@2|Bacteria,COG0745@2|Bacteria,4NGSQ@976|Bacteroidetes,2FM60@200643|Bacteroidia,3XJR0@558415|Marinilabiliaceae	976|Bacteroidetes	GKT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppsA	-	-	-	-	-	-	-	-	-	-	-	PPDK_N,Response_reg
TLS3_k127_7140135_1	1168289.AJKI01000011_gene479	1.542e-129	419.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,2FM9P@200643|Bacteroidia,3XJDD@558415|Marinilabiliaceae	976|Bacteroidetes	I	Acyl transferase domain	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
TLS3_k127_7140135_3	927658.AJUM01000034_gene176	9.335e-92	306.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,2FMYB@200643|Bacteroidia,3XIT5@558415|Marinilabiliaceae	976|Bacteroidetes	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
TLS3_k127_7140135_4	1408813.AYMG01000001_gene3724	2.668e-52	187.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1IXEM@117747|Sphingobacteriia	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
TLS3_k127_7140135_5	468059.AUHA01000002_gene549	7.331e-36	147.0	COG0775@1|root,COG0775@2|Bacteria,4NQVQ@976|Bacteroidetes,1IT1C@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnB	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
TLS3_k127_7140135_2	1408473.JHXO01000004_gene30	7.112e-103	342.0	COG2107@1|root,COG2107@2|Bacteria,4NFAN@976|Bacteroidetes	976|Bacteroidetes	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
TLS3_k127_7142491_10	388413.ALPR1_06685	7.437e-05	47.0	COG4299@1|root,COG4299@2|Bacteria,4NH8T@976|Bacteroidetes,47KYS@768503|Cytophagia	976|Bacteroidetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
TLS3_k127_7142491_4	237368.SCABRO_00972	1.653e-38	154.0	COG0483@1|root,COG0483@2|Bacteria,2IZ8Y@203682|Planctomycetes	203682|Planctomycetes	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
TLS3_k127_7142491_6	644282.Deba_0188	7.419e-24	118.0	COG1629@1|root,COG4771@2|Bacteria,1QZ2F@1224|Proteobacteria,42PWH@68525|delta/epsilon subdivisions,2X7S7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
TLS3_k127_7142491_7	1121101.HMPREF1532_03397	5.248e-14	78.0	2DX1N@1|root,32V2J@2|Bacteria,4NT61@976|Bacteroidetes,2FTUX@200643|Bacteroidia,4AS36@815|Bacteroidaceae	976|Bacteroidetes	S	Protein of unknown function (DUF3788)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3788
TLS3_k127_7142491_5	272559.BF9343_1898	2.697e-35	138.0	2DMZP@1|root,32UMQ@2|Bacteria,4P3H1@976|Bacteroidetes,2FT4E@200643|Bacteroidia,4ARGU@815|Bacteroidaceae	976|Bacteroidetes	S	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
TLS3_k127_7142491_9	1122176.KB903574_gene4818	4.884e-08	64.0	2C08E@1|root,2ZBCG@2|Bacteria,4NGBR@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7142491_0	1185876.BN8_06618	6.122e-163	533.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
TLS3_k127_7142491_8	1168034.FH5T_17035	4.739e-09	63.0	2DU44@1|root,33NVG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7142491_3	1408473.JHXO01000010_gene3620	7.285e-57	209.0	COG0607@1|root,COG0607@2|Bacteria,4NPZQ@976|Bacteroidetes	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS3_k127_7142491_1	1408473.JHXO01000010_gene3621	7.443e-85	284.0	COG2391@1|root,COG2391@2|Bacteria,4NMK0@976|Bacteroidetes,2FW98@200643|Bacteroidia	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Rhodanese,Sulf_transp
TLS3_k127_7142491_2	1408473.JHXO01000010_gene3622	1.323e-68	238.0	COG2391@1|root,COG2391@2|Bacteria,4NGS1@976|Bacteroidetes,2FXKE@200643|Bacteroidia	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
TLS3_k127_7168378_2	1168289.AJKI01000002_gene2652	1.739e-127	413.0	COG4975@1|root,COG4975@2|Bacteria,4NF22@976|Bacteroidetes,2FMYN@200643|Bacteroidia,3XKR5@558415|Marinilabiliaceae	976|Bacteroidetes	G	Ureide permease	glcU	-	-	ko:K05340	-	-	-	-	ko00000,ko02000	2.A.7.5	-	-	Ureide_permease
TLS3_k127_7168378_1	1168289.AJKI01000031_gene1070	6.649e-128	417.0	COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,2FM3E@200643|Bacteroidia,3XJUC@558415|Marinilabiliaceae	976|Bacteroidetes	EJ	Asparaginase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
TLS3_k127_7168378_4	1392498.JQLH01000001_gene669	2.129e-82	282.0	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,1HXDX@117743|Flavobacteriia,2PGZ5@252356|Maribacter	976|Bacteroidetes	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
TLS3_k127_7168378_0	926549.KI421517_gene3334	1.215e-225	705.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,47MQD@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdh	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009986,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
TLS3_k127_7168378_3	694427.Palpr_2054	1.098e-120	398.0	COG0758@1|root,COG1948@1|root,COG0758@2|Bacteria,COG1948@2|Bacteria,4NF7T@976|Bacteroidetes,2FKYE@200643|Bacteroidia,22WZ4@171551|Porphyromonadaceae	976|Bacteroidetes	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
TLS3_k127_7178888_1	1086011.HJ01_02261	2.045e-148	510.0	COG2911@1|root,COG3209@1|root,COG3210@1|root,COG4733@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,4NKIP@976|Bacteroidetes,1I0IX@117743|Flavobacteriia	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,Gal_Lectin
TLS3_k127_7178888_5	216432.CA2559_10353	1.068e-10	69.0	2EKFG@1|root,33E5M@2|Bacteria,4PQ2F@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4402
TLS3_k127_7178888_6	296591.Bpro_5314	4.322e-07	59.0	2AN3B@1|root,31D0Z@2|Bacteria,1PWKM@1224|Proteobacteria,2VXPG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4402
TLS3_k127_7178888_2	1086011.HJ01_02264	3.729e-71	250.0	COG3121@1|root,COG3121@2|Bacteria,4NK7D@976|Bacteroidetes,1I142@117743|Flavobacteriia,2NWTM@237|Flavobacterium	976|Bacteroidetes	NU	Chaperone	-	-	-	-	-	-	-	-	-	-	-	-	PapD_N
TLS3_k127_7178888_0	1086011.HJ01_02266	9.277e-211	694.0	COG3188@1|root,COG3188@2|Bacteria,4NFPY@976|Bacteroidetes,1HXS8@117743|Flavobacteriia,2NV8Z@237|Flavobacterium	976|Bacteroidetes	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7178888_3	1123274.KB899425_gene2737	2.661e-49	183.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_3
TLS3_k127_7187020_4	435591.BDI_1325	2.886e-19	91.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,2FRKH@200643|Bacteroidia,22Z9V@171551|Porphyromonadaceae	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
TLS3_k127_7187020_0	1408473.JHXO01000012_gene314	6.537e-205	649.0	COG0520@1|root,COG0520@2|Bacteria,4NERR@976|Bacteroidetes,2FWRC@200643|Bacteroidia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
TLS3_k127_7187020_2	1454004.AW11_03405	1.88e-40	157.0	COG0500@1|root,COG0500@2|Bacteria,1R0QC@1224|Proteobacteria,2WHV7@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7187020_1	290317.Cpha266_1001	7.706e-42	157.0	COG1765@1|root,COG1765@2|Bacteria,1FE41@1090|Chlorobi	1090|Chlorobi	O	PFAM OsmC family protein	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC
TLS3_k127_7187020_3	1408473.JHXO01000006_gene1119	2.139e-21	94.0	COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,2FN9P@200643|Bacteroidia	976|Bacteroidetes	G	Xylose isomerase	xylA	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	-
TLS3_k127_7197268_1	886379.AEWI01000005_gene913	5.696e-109	361.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,2FNG4@200643|Bacteroidia,3XJ51@558415|Marinilabiliaceae	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_7197268_3	485918.Cpin_6211	2.585e-37	143.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,1ITGS@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
TLS3_k127_7197268_0	1408473.JHXO01000006_gene1191	0.0	1054.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,2FNKR@200643|Bacteroidia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
TLS3_k127_7197268_2	1408473.JHXO01000006_gene1207	8.938e-60	211.0	COG0669@1|root,COG0669@2|Bacteria,4NM84@976|Bacteroidetes,2FT6A@200643|Bacteroidia	976|Bacteroidetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
TLS3_k127_7197268_4	869213.JCM21142_271	3.357e-18	87.0	COG1051@1|root,COG1051@2|Bacteria,4NS9I@976|Bacteroidetes,47NQ9@768503|Cytophagia	976|Bacteroidetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_7206029_0	886379.AEWI01000137_gene2260	3.386e-273	850.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,2FNBD@200643|Bacteroidia,3XJ69@558415|Marinilabiliaceae	976|Bacteroidetes	L	Ultra-violet resistance protein B	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
TLS3_k127_7206029_1	1510531.JQJJ01000010_gene2442	3.088e-84	287.0	COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,3K48K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
TLS3_k127_7206029_2	933262.AXAM01000081_gene2263	1.21e-45	171.0	COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,42N0R@68525|delta/epsilon subdivisions,2WMPF@28221|Deltaproteobacteria,2MKPX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Fer2_BFD
TLS3_k127_7210467_2	1237149.C900_05250	4.156e-80	287.0	COG4775@1|root,COG4775@2|Bacteria,4NF38@976|Bacteroidetes,47KMS@768503|Cytophagia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7210467_1	1433126.BN938_3047	2.485e-80	274.0	2BB8B@1|root,324R0@2|Bacteria,4NQG8@976|Bacteroidetes,2FXHA@200643|Bacteroidia,22USQ@171550|Rikenellaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7210467_0	1237149.C900_04731	9.565e-175	552.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,47JTQ@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
TLS3_k127_7218241_1	1235803.C825_04658	1.186e-168	539.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,2FNRC@200643|Bacteroidia,22X3X@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
TLS3_k127_7218241_2	1168034.FH5T_14425	3.962e-74	265.0	COG1506@1|root,COG1506@2|Bacteria,4NGW1@976|Bacteroidetes,2FV5N@200643|Bacteroidia	976|Bacteroidetes	E	Secretory lipase	-	-	-	-	-	-	-	-	-	-	-	-	LIP,Peptidase_S9
TLS3_k127_7218241_0	1408473.JHXO01000005_gene1443	1.451e-243	770.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,2FMY5@200643|Bacteroidia	976|Bacteroidetes	S	ABC transporter, ATP-binding protein	yheS_3	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
TLS3_k127_7218241_3	1201290.M902_2018	1.074e-37	151.0	COG3884@1|root,COG3884@2|Bacteria,1MYMU@1224|Proteobacteria,43BEI@68525|delta/epsilon subdivisions,2MT2J@213481|Bdellovibrionales,2X6T3@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	Acyl-ACP thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-ACP_TE
TLS3_k127_7218241_4	926562.Oweho_1029	2.206e-36	154.0	28H6U@1|root,2Z7J5@2|Bacteria,4NHUU@976|Bacteroidetes,1I8FZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7233802_6	1382305.AZUC01000054_gene2029	1.227e-12	68.0	COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,4HA6P@91061|Bacilli,26EEP@186818|Planococcaceae	91061|Bacilli	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09430	FumaraseC_C,Lyase_1
TLS3_k127_7233802_7	1408473.JHXO01000008_gene2667	6.023e-11	67.0	COG4980@1|root,COG4980@2|Bacteria,4NW56@976|Bacteroidetes,2FZ4H@200643|Bacteroidia	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
TLS3_k127_7233802_0	362418.IW19_23060	1.255e-138	458.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,1HYT4@117743|Flavobacteriia,2NTH0@237|Flavobacterium	976|Bacteroidetes	L	DNA ligase	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
TLS3_k127_7233802_3	362418.IW19_23055	9.527e-84	285.0	COG1273@1|root,COG1273@2|Bacteria,4NHHQ@976|Bacteroidetes,1HZ9G@117743|Flavobacteriia,2NUEP@237|Flavobacterium	976|Bacteroidetes	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
TLS3_k127_7233802_1	1123008.KB905697_gene3141	1.704e-134	437.0	COG3569@1|root,COG3569@2|Bacteria,4NGTF@976|Bacteroidetes,2FXD4@200643|Bacteroidia,22ZDR@171551|Porphyromonadaceae	976|Bacteroidetes	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
TLS3_k127_7233802_2	485918.Cpin_0994	9.392e-100	335.0	COG1028@1|root,COG1028@2|Bacteria,4NFK6@976|Bacteroidetes,1IQDY@117747|Sphingobacteriia	976|Bacteroidetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_7233802_4	1453498.LG45_03130	8.811e-57	202.0	COG0745@1|root,COG0745@2|Bacteria,4NPID@976|Bacteroidetes,1I236@117743|Flavobacteriia,2NUGC@237|Flavobacterium	976|Bacteroidetes	KT	Regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_7233802_5	1250006.JHZZ01000001_gene1797	1.071e-17	88.0	COG4251@1|root,COG5278@1|root,COG4251@2|Bacteria,COG5278@2|Bacteria,4NGXA@976|Bacteroidetes,1HY3D@117743|Flavobacteriia,3VX5Q@52959|Polaribacter	976|Bacteroidetes	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS_3,PAS_9
TLS3_k127_7235652_0	742817.HMPREF9449_01812	9.421e-193	610.0	COG2271@1|root,COG2271@2|Bacteria,4PKTC@976|Bacteroidetes,2G3HT@200643|Bacteroidia,23233@171551|Porphyromonadaceae	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_7235652_2	926562.Oweho_3011	2.857e-38	150.0	COG2143@1|root,COG2143@2|Bacteria,4PJYZ@976|Bacteroidetes,1ID1F@117743|Flavobacteriia,2PBWE@246874|Cryomorphaceae	976|Bacteroidetes	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH
TLS3_k127_7235652_3	1168289.AJKI01000010_gene1641	1.095e-24	117.0	28M15@1|root,2ZAG0@2|Bacteria,4NJBY@976|Bacteroidetes,2FMGZ@200643|Bacteroidia,3XJ29@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4831)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4831
TLS3_k127_7235652_1	1168034.FH5T_11685	4.536e-136	447.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,2FQ4K@200643|Bacteroidia	976|Bacteroidetes	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
TLS3_k127_7256190_0	886379.AEWI01000005_gene928	6.519e-139	479.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NKGA@976|Bacteroidetes,2G0DG@200643|Bacteroidia,3XJHT@558415|Marinilabiliaceae	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,SpoIIE,Y_Y_Y
TLS3_k127_7256190_1	869213.JCM21142_93472	4.515e-85	287.0	COG5012@1|root,COG5012@2|Bacteria,4P0JY@976|Bacteroidetes	976|Bacteroidetes	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
TLS3_k127_7256190_2	1487923.DP73_21445	1.138e-75	263.0	COG1410@1|root,COG1410@2|Bacteria,1VRVS@1239|Firmicutes,25EJA@186801|Clostridia,267HQ@186807|Peptococcaceae	186801|Clostridia	E	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind
TLS3_k127_7256190_3	1232410.KI421424_gene1692	4.635e-57	214.0	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria,43V05@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Methylenetetrahydrofolate reductase	metF-1	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
TLS3_k127_7264839_0	435591.BDI_3062	3.326e-238	769.0	COG1452@1|root,COG1629@1|root,COG1452@2|Bacteria,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,22WXV@171551|Porphyromonadaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_7264839_1	929556.Solca_3671	1.562e-94	327.0	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,1IPKS@117747|Sphingobacteriia	976|Bacteroidetes	S	Ragb susd	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_7264839_3	1144313.PMI10_03296	3.186e-26	119.0	28MFR@1|root,2ZAT4@2|Bacteria,4NM07@976|Bacteroidetes,1I8GJ@117743|Flavobacteriia,2NUEF@237|Flavobacterium	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_7264839_2	694427.Palpr_2006	9.311e-30	125.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,2FM8G@200643|Bacteroidia,22VX0@171551|Porphyromonadaceae	976|Bacteroidetes	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Glycoamylase
TLS3_k127_7286366_4	886379.AEWI01000020_gene1323	6.954e-48	177.0	COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,2FQV3@200643|Bacteroidia,3XK0F@558415|Marinilabiliaceae	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_7286366_1	1123248.KB893315_gene3183	1.541e-117	385.0	COG0484@1|root,COG0484@2|Bacteria,4NE4X@976|Bacteroidetes,1IPQG@117747|Sphingobacteriia	976|Bacteroidetes	O	chaperone DnaJ	dnaJ2	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
TLS3_k127_7286366_0	1131812.JQMS01000001_gene2326	2.283e-119	407.0	COG4775@1|root,COG4775@2|Bacteria,4NF38@976|Bacteroidetes,1HY9C@117743|Flavobacteriia,2NTF2@237|Flavobacterium	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7286366_8	760192.Halhy_5660	9.194e-07	55.0	2EBJZ@1|root,335KD@2|Bacteria,4NWP2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7286366_5	1086011.HJ01_03475	4.006e-20	94.0	2EC34@1|root,33623@2|Bacteria,4NVW7@976|Bacteroidetes,1I737@117743|Flavobacteriia,2NWAU@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
TLS3_k127_7286366_6	1408473.JHXO01000008_gene2667	1.901e-19	91.0	COG4980@1|root,COG4980@2|Bacteria,4NW56@976|Bacteroidetes,2FZ4H@200643|Bacteroidia	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
TLS3_k127_7286366_7	1123057.P872_24550	1.812e-14	74.0	2EFZF@1|root,339RM@2|Bacteria,4NXMV@976|Bacteroidetes,47SRN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
TLS3_k127_7286366_2	700598.Niako_0027	1.511e-74	255.0	COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,1ISDK@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_7286366_3	641524.ADICYQ_5445	1.151e-66	238.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,4P15P@976|Bacteroidetes,47XWZ@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,TPR_12,TPR_8
TLS3_k127_7288114_0	1408473.JHXO01000011_gene3043	9.924e-165	530.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,2FNK9@200643|Bacteroidia	976|Bacteroidetes	I	AMP-binding enzyme	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
TLS3_k127_7288114_6	742726.HMPREF9448_01157	2.128e-10	67.0	2EKJZ@1|root,33E9V@2|Bacteria,4NXVU@976|Bacteroidetes,2FVUN@200643|Bacteroidia,22YWX@171551|Porphyromonadaceae	976|Bacteroidetes	S	COG NOG30522 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7288114_5	869213.JCM21142_42086	4.887e-24	111.0	28JHY@1|root,2Z9BE@2|Bacteria,4NVN1@976|Bacteroidetes,47SUR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7288114_1	1237149.C900_00992	1.102e-163	527.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,47KNW@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
TLS3_k127_7288114_3	449673.BACSTE_01222	1.351e-86	291.0	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,2FM1C@200643|Bacteroidia,4AKI1@815|Bacteroidaceae	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
TLS3_k127_7288114_4	1408473.JHXO01000006_gene1149	3.065e-75	262.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,2FQ14@200643|Bacteroidia	976|Bacteroidetes	S	Glycosyltransferase, group 2 family protein	wbbL	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_7288114_2	509635.N824_21625	1.271e-125	417.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1IP3U@117747|Sphingobacteriia	976|Bacteroidetes	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bfmBB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS3_k127_7308822_0	709991.Odosp_3390	1.397e-269	848.0	COG3534@1|root,COG3534@2|Bacteria,4NHR5@976|Bacteroidetes,2G2XU@200643|Bacteroidia,231K5@171551|Porphyromonadaceae	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
TLS3_k127_7315435_3	204669.Acid345_0209	9.809e-22	108.0	COG4219@1|root,COG4219@2|Bacteria,3Y4QS@57723|Acidobacteria,2JKFK@204432|Acidobacteriia	204432|Acidobacteriia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
TLS3_k127_7315435_1	1189612.A33Q_0331	2.445e-35	141.0	2E3HM@1|root,32YG7@2|Bacteria,4NW2A@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7315435_2	1191523.MROS_1283	1.389e-28	121.0	COG3439@1|root,COG3439@2|Bacteria	2|Bacteria	D	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
TLS3_k127_7315435_4	945713.IALB_2789	2.549e-13	72.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin
TLS3_k127_7315435_0	1121413.JMKT01000009_gene1984	2.635e-45	169.0	COG0574@1|root,COG0574@2|Bacteria,1N38V@1224|Proteobacteria,42MWC@68525|delta/epsilon subdivisions,2WKAZ@28221|Deltaproteobacteria,2M7TZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
TLS3_k127_7317532_0	865937.Gilli_3176	0.0	1041.0	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1HXBI@117743|Flavobacteriia,2P6HC@244698|Gillisia	976|Bacteroidetes	G	Glycosyl hydrolase family 65 central catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
TLS3_k127_7317532_1	1123234.AUKI01000019_gene506	4.48e-185	592.0	COG2133@1|root,COG2133@2|Bacteria,4NFN2@976|Bacteroidetes	976|Bacteroidetes	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
TLS3_k127_7317532_2	1124780.ANNU01000067_gene413	9.174e-18	87.0	COG2010@1|root,COG2010@2|Bacteria,4NXD9@976|Bacteroidetes,47S4N@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
TLS3_k127_7317532_3	1148.1652727	1.49e-13	76.0	COG1359@1|root,COG1359@2|Bacteria,1G94C@1117|Cyanobacteria,1H5XK@1142|Synechocystis	1117|Cyanobacteria	S	Antibiotic biosynthesis monooxygenase	-	GO:0003674,GO:0003824	-	-	-	-	-	-	-	-	-	-	ABM
TLS3_k127_7317982_4	99598.Cal7507_3642	4.746e-11	66.0	2EMYS@1|root,33FKY@2|Bacteria,1GF1P@1117|Cyanobacteria,1HPVB@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
TLS3_k127_7317982_3	1121405.dsmv_1643	1.907e-32	130.0	COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,42TWN@68525|delta/epsilon subdivisions,2WQDD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	OsmC-like protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
TLS3_k127_7317982_2	1237149.C900_02491	5.46e-39	150.0	COG5502@1|root,COG5502@2|Bacteria,4NWIK@976|Bacteroidetes,47WNG@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
TLS3_k127_7317982_1	714943.Mucpa_6800	2.254e-76	270.0	COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,1ISE9@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
TLS3_k127_7317982_0	714943.Mucpa_6801	6.735e-105	351.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,1IRGP@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_7320915_4	435591.BDI_2554	1.653e-67	232.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,2FMKB@200643|Bacteroidia,22WPQ@171551|Porphyromonadaceae	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_7320915_1	742766.HMPREF9455_00386	2.752e-122	401.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,2FPUC@200643|Bacteroidia,22WCU@171551|Porphyromonadaceae	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_7320915_0	497964.CfE428DRAFT_0160	1.789e-138	460.0	COG1657@1|root,COG1657@2|Bacteria,46UEC@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Squalene-hopene cyclase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans,SQHop_cyclase_C
TLS3_k127_7320915_5	1396418.BATQ01000175_gene2764	1.238e-20	102.0	COG5029@1|root,COG5029@2|Bacteria,46URI@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
TLS3_k127_7320915_3	1396418.BATQ01000044_gene6461	1.329e-109	374.0	COG0142@1|root,COG1852@1|root,COG0142@2|Bacteria,COG1852@2|Bacteria,46TEA@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Protein of unknown function DUF116	-	-	-	-	-	-	-	-	-	-	-	-	DUF116,polyprenyl_synt
TLS3_k127_7320915_2	1168034.FH5T_05300	2.761e-113	373.0	COG0535@1|root,COG0535@2|Bacteria,4NQ4R@976|Bacteroidetes,2FT2F@200643|Bacteroidia	976|Bacteroidetes	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
TLS3_k127_7323017_5	771875.Ferpe_0111	0.0001414	46.0	COG0726@1|root,COG0726@2|Bacteria,2GDI4@200918|Thermotogae	200918|Thermotogae	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7323017_3	694427.Palpr_0805	6.661e-41	162.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
TLS3_k127_7323017_1	906968.Trebr_0251	1.158e-116	383.0	COG0039@1|root,COG0039@2|Bacteria,2J64G@203691|Spirochaetes	203691|Spirochaetes	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
TLS3_k127_7323017_2	946077.W5A_08257	5.851e-87	293.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1HY06@117743|Flavobacteriia	976|Bacteroidetes	D	atp-binding protein	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
TLS3_k127_7323017_0	1408473.JHXO01000011_gene3152	5.812e-207	679.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,2FM3C@200643|Bacteroidia	976|Bacteroidetes	G	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
TLS3_k127_7323017_4	1120968.AUBX01000009_gene588	3.436e-10	72.0	COG4773@1|root,COG4773@2|Bacteria,4PKTX@976|Bacteroidetes,47Y4C@768503|Cytophagia	976|Bacteroidetes	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
TLS3_k127_7359819_4	869213.JCM21142_41796	1.73e-18	85.0	COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,47JGP@768503|Cytophagia	976|Bacteroidetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
TLS3_k127_7359819_2	743722.Sph21_2405	7.15e-52	186.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,1ISEQ@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
TLS3_k127_7359819_1	927658.AJUM01000042_gene1625	0.0	2126.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,2FMDI@200643|Bacteroidia,3XIWW@558415|Marinilabiliaceae	976|Bacteroidetes	K	RNA polymerase beta subunit external 1 domain	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
TLS3_k127_7359819_0	886379.AEWI01000010_gene636	0.0	2357.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,3XJJC@558415|Marinilabiliaceae	976|Bacteroidetes	K	RNA polymerase I subunit A N-terminus	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
TLS3_k127_7359819_3	1168034.FH5T_04165	3.417e-42	158.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,2FTSX@200643|Bacteroidia	976|Bacteroidetes	T	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
TLS3_k127_7359819_5	886377.Murru_1462	2.256e-08	58.0	COG0399@1|root,COG0399@2|Bacteria,4NVFZ@976|Bacteroidetes,1I3II@117743|Flavobacteriia	976|Bacteroidetes	M	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
TLS3_k127_7380624_0	153721.MYP_4272	7.1e-307	983.0	COG0204@1|root,COG4258@1|root,COG0204@2|Bacteria,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,47P2T@768503|Cytophagia	976|Bacteroidetes	I	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
TLS3_k127_7380624_1	1123008.KB905694_gene1758	7.04e-111	370.0	COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,4NETR@976|Bacteroidetes,2FQIT@200643|Bacteroidia,22X2B@171551|Porphyromonadaceae	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DUF2062,Glycos_transf_2
TLS3_k127_7397516_0	946077.W5A_07125	3.965e-200	638.0	COG1395@1|root,COG1395@2|Bacteria,4NEA1@976|Bacteroidetes,1I100@117743|Flavobacteriia	976|Bacteroidetes	K	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_7397516_1	700598.Niako_1951	1.157e-88	312.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia	976|Bacteroidetes	V	TIGRFAM Acidobacterial duplicated orphan permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_7434031_1	709991.Odosp_2327	4.88e-76	256.0	COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,2FRZE@200643|Bacteroidia,22XNJ@171551|Porphyromonadaceae	976|Bacteroidetes	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
TLS3_k127_7434031_5	1408473.JHXO01000006_gene1290	1.546e-17	84.0	COG0255@1|root,COG0255@2|Bacteria,4NUSC@976|Bacteroidetes,2FUJB@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
TLS3_k127_7434031_4	742725.HMPREF9450_00064	1.024e-37	142.0	COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,2FTXY@200643|Bacteroidia,22UIB@171550|Rikenellaceae	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
TLS3_k127_7434031_2	1501391.LG35_06770	4.747e-62	214.0	COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,2FSG8@200643|Bacteroidia,22UFG@171550|Rikenellaceae	976|Bacteroidetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
TLS3_k127_7434031_3	1408473.JHXO01000006_gene1293	7.862e-50	179.0	COG0198@1|root,COG0198@2|Bacteria,4NSTI@976|Bacteroidetes,2FT5V@200643|Bacteroidia	976|Bacteroidetes	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
TLS3_k127_7434031_0	880526.KE386488_gene497	3.586e-84	282.0	COG0094@1|root,COG0094@2|Bacteria,4NEGY@976|Bacteroidetes,2FM5Y@200643|Bacteroidia,22U02@171550|Rikenellaceae	976|Bacteroidetes	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
TLS3_k127_7442748_1	118005.AWNK01000005_gene1430	8.187e-15	79.0	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,DUF4118,EAL,GGDEF,PAS_3,PAS_9
TLS3_k127_7442748_0	927658.AJUM01000010_gene1352	7.229e-212	678.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,4NDXU@976|Bacteroidetes,2FRUD@200643|Bacteroidia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Response_reg
TLS3_k127_7442748_2	1173022.Cri9333_2453	6.59e-12	67.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1G06C@1117|Cyanobacteria,1H8Z5@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
TLS3_k127_7458829_1	761193.Runsl_5353	4.488e-82	282.0	COG4784@1|root,COG4784@2|Bacteria,4PM59@976|Bacteroidetes,47MK2@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TLS3_k127_7458829_0	1237149.C900_04485	7.567e-126	406.0	COG2013@1|root,COG2013@2|Bacteria,4NFNA@976|Bacteroidetes,47KS9@768503|Cytophagia	976|Bacteroidetes	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
TLS3_k127_7458829_2	1349785.BAUG01000033_gene1908	8.801e-61	230.0	28HH2@1|root,2Z7ST@2|Bacteria,4NMWR@976|Bacteroidetes,1I1Q4@117743|Flavobacteriia	976|Bacteroidetes	M	Thiol-activated cytolysin	-	-	-	ko:K11031	ko02024,map02024	-	-	-	ko00000,ko00001,ko02042	-	-	-	Thiol_cytolysin
TLS3_k127_7458829_3	313606.M23134_06385	2.539e-15	87.0	COG0457@1|root,COG0457@2|Bacteria,4NGS0@976|Bacteroidetes,47MD8@768503|Cytophagia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_8
TLS3_k127_7458829_4	269798.CHU_0400	1.287e-09	59.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,4NGJ4@976|Bacteroidetes,47KIQ@768503|Cytophagia	976|Bacteroidetes	G	Trehalose-phosphatase	otsA	-	2.4.1.15,3.1.3.12	ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
TLS3_k127_7480079_1	880074.BARVI_03030	7.391e-160	526.0	COG1874@1|root,COG1874@2|Bacteria,4PNM8@976|Bacteroidetes,2G105@200643|Bacteroidia,22YWU@171551|Porphyromonadaceae	976|Bacteroidetes	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7480079_0	1492737.FEM08_00390	6.389e-174	558.0	COG0659@1|root,COG0659@2|Bacteria,4NF1C@976|Bacteroidetes,1HX8C@117743|Flavobacteriia,2NSXV@237|Flavobacterium	976|Bacteroidetes	P	Sulfate permease	ychM	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
TLS3_k127_7488640_1	760192.Halhy_0309	4.532e-31	132.0	28J3Q@1|root,2Z8ZW@2|Bacteria,4NGJW@976|Bacteroidetes,1IUBQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (Porph_ging)	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
TLS3_k127_7488640_0	1189612.A33Q_0622	1.886e-69	245.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,47JEF@768503|Cytophagia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
TLS3_k127_7489173_3	927658.AJUM01000042_gene1687	1.614e-72	250.0	COG4775@1|root,COG4775@2|Bacteria,4NMIQ@976|Bacteroidetes,2FS3R@200643|Bacteroidia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
TLS3_k127_7489173_2	1168034.FH5T_11665	3.102e-84	295.0	COG5505@1|root,COG5505@2|Bacteria,4NPE1@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
TLS3_k127_7489173_1	709991.Odosp_0765	3.263e-121	394.0	COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,2FM85@200643|Bacteroidia,22W1Y@171551|Porphyromonadaceae	976|Bacteroidetes	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_7489173_0	1408473.JHXO01000013_gene529	1.496e-160	522.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,2FMIG@200643|Bacteroidia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
TLS3_k127_7489173_4	1168034.FH5T_17555	7.302e-58	206.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,2FP92@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
TLS3_k127_748978_1	1433126.BN938_1871	2.861e-193	611.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,2FNSI@200643|Bacteroidia,22UB4@171550|Rikenellaceae	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
TLS3_k127_748978_0	1349822.NSB1T_01125	1.245e-237	748.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,2FN06@200643|Bacteroidia,22VUX@171551|Porphyromonadaceae	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
TLS3_k127_7519972_6	1408473.JHXO01000001_gene2047	1.123e-60	213.0	COG1629@1|root,COG4771@2|Bacteria,4NE4M@976|Bacteroidetes,2FNUY@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_7519972_7	886379.AEWI01000001_gene1712	2.254e-48	184.0	COG0789@1|root,COG0789@2|Bacteria,4NERC@976|Bacteroidetes,2FWI5@200643|Bacteroidia,3XJCX@558415|Marinilabiliaceae	976|Bacteroidetes	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
TLS3_k127_7519972_4	203275.BFO_2751	1.424e-95	318.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,2FMHD@200643|Bacteroidia,22XG8@171551|Porphyromonadaceae	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
TLS3_k127_7519972_2	1168034.FH5T_05455	4.362e-174	557.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,2FMNM@200643|Bacteroidia	976|Bacteroidetes	K	Sigma-54 interaction domain protein	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
TLS3_k127_7519972_8	1501391.LG35_02455	1.338e-39	154.0	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,2FSVU@200643|Bacteroidia,22VDD@171550|Rikenellaceae	976|Bacteroidetes	S	Lipopolysaccharide-assembly	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
TLS3_k127_7519972_11	1408473.JHXO01000001_gene2394	1.654e-23	109.0	28HHN@1|root,2Z7TA@2|Bacteria,4NEXR@976|Bacteroidetes,2FQ6G@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7519972_10	1168034.FH5T_05440	2.579e-29	120.0	COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,2FSK4@200643|Bacteroidia	976|Bacteroidetes	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
TLS3_k127_7519972_9	927658.AJUM01000034_gene232	2.681e-38	144.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,2FT5R@200643|Bacteroidia,3XK72@558415|Marinilabiliaceae	976|Bacteroidetes	O	Chaperonin 10 Kd subunit	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
TLS3_k127_7519972_1	1168034.FH5T_05420	2.437e-279	865.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
TLS3_k127_7519972_0	742725.HMPREF9450_01835	8.971e-311	959.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,2FM9V@200643|Bacteroidia,22UZW@171550|Rikenellaceae	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
TLS3_k127_7519972_5	1349822.NSB1T_08355	2.084e-90	302.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia,22WBV@171551|Porphyromonadaceae	976|Bacteroidetes	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_7519972_3	385682.AFSL01000090_gene951	4.412e-96	333.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,2FPG5@200643|Bacteroidia,3XJX7@558415|Marinilabiliaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_7520602_2	1392488.JHZY01000002_gene63	1.659e-121	395.0	COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,1HYF4@117743|Flavobacteriia,2XK0V@283735|Leeuwenhoekiella	976|Bacteroidetes	GM	GDP-mannose 4,6 dehydratase	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
TLS3_k127_7520602_0	331678.Cphamn1_1932	9.356e-162	515.0	COG1089@1|root,COG1089@2|Bacteria	2|Bacteria	M	GDP-mannose 4,6-dehydratase activity	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
TLS3_k127_7520602_1	1347342.BN863_33650	5.295e-151	486.0	COG0615@1|root,COG2605@1|root,COG0615@2|Bacteria,COG2605@2|Bacteria,4NGSD@976|Bacteroidetes	976|Bacteroidetes	IM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,GHMP_kinases_C
TLS3_k127_7537245_0	1203611.KB894543_gene1819	4.361e-97	327.0	COG1032@1|root,COG1032@2|Bacteria,4NKFV@976|Bacteroidetes	976|Bacteroidetes	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
TLS3_k127_7537245_3	714943.Mucpa_6804	1.516e-25	111.0	COG4706@1|root,COG4706@2|Bacteria,4NSB5@976|Bacteroidetes,1IU4J@117747|Sphingobacteriia	976|Bacteroidetes	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7537245_1	1121904.ARBP01000002_gene6822	1.638e-69	237.0	2DK0G@1|root,30823@2|Bacteria,4NNIV@976|Bacteroidetes,47PPM@768503|Cytophagia	976|Bacteroidetes	S	Rifampin ADP-ribosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Arr-ms
TLS3_k127_7537245_2	694427.Palpr_0170	2.243e-53	198.0	COG0577@1|root,COG0577@2|Bacteria,4NFGD@976|Bacteroidetes,2FNP6@200643|Bacteroidia,22VZ8@171551|Porphyromonadaceae	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_7561525_4	1349785.BAUG01000012_gene946	2.591e-77	270.0	COG1216@1|root,COG1216@2|Bacteria,4PKBZ@976|Bacteroidetes,1IJBV@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
TLS3_k127_7561525_2	1047013.AQSP01000092_gene316	1.034e-126	419.0	COG1902@1|root,COG1902@2|Bacteria	2|Bacteria	C	pentaerythritol trinitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Oxidored_FMN
TLS3_k127_7561525_0	1047013.AQSP01000126_gene2747	1.883e-214	684.0	COG1053@1|root,COG1053@2|Bacteria,2NQEG@2323|unclassified Bacteria	2|Bacteria	C	FAD binding domain	-	-	1.4.3.16,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K00278,ko:K03388	ko00250,ko00680,ko00760,ko01100,ko01120,ko01200,map00250,map00680,map00760,map01100,map01120,map01200	M00115,M00356,M00357,M00563,M00567	R00357,R00481,R04540,R11928,R11931,R11943,R11944	RC00006,RC00011,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
TLS3_k127_7561525_3	1047013.AQSP01000126_gene2736	2.006e-79	273.0	COG1028@1|root,COG1028@2|Bacteria,2NQUH@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_7561525_1	929713.NIASO_00530	8.716e-165	527.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1INV5@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
TLS3_k127_7561525_5	1396141.BATP01000047_gene3890	4.642e-08	60.0	COG2010@1|root,COG4454@1|root,COG2010@2|Bacteria,COG4454@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K14588	-	-	-	-	ko00000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1,Cytochrom_C,Cytochrome_CBB3
TLS3_k127_7585852_0	926550.CLDAP_30580	1.33e-182	585.0	COG0297@1|root,COG0297@2|Bacteria,2G60C@200795|Chloroflexi	200795|Chloroflexi	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
TLS3_k127_7585852_1	335543.Sfum_2348	6.107e-178	565.0	COG0438@1|root,COG0438@2|Bacteria,1MYTB@1224|Proteobacteria,42MCA@68525|delta/epsilon subdivisions,2WJVX@28221|Deltaproteobacteria,2MQT9@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
TLS3_k127_7593732_1	1122226.AUHX01000008_gene1539	7.496e-90	304.0	COG1230@1|root,COG1230@2|Bacteria,4NIHB@976|Bacteroidetes,1HXN8@117743|Flavobacteriia	976|Bacteroidetes	P	cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
TLS3_k127_7593732_3	880073.Calab_3021	1.94e-30	130.0	COG1280@1|root,COG1280@2|Bacteria	2|Bacteria	E	homoserine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	LysE,SfLAP
TLS3_k127_7593732_2	1270196.JCKI01000002_gene339	1.191e-66	233.0	COG0454@1|root,COG0456@2|Bacteria,4NNG9@976|Bacteroidetes,1ISS7@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
TLS3_k127_7593732_0	1317122.ATO12_11325	1.784e-197	646.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HWM8@117743|Flavobacteriia,2YJA9@290174|Aquimarina	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_76045_6	96561.Dole_1678	4.858e-43	167.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria,1MUB8@1224|Proteobacteria,42NWQ@68525|delta/epsilon subdivisions,2WM5R@28221|Deltaproteobacteria,2MJ8Y@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,PAS,PAS_4
TLS3_k127_76045_5	290512.Paes_2194	1.131e-58	215.0	COG1352@1|root,COG1352@2|Bacteria	2|Bacteria	NT	protein-glutamate O-methyltransferase activity	cheR	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K03408,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,CheW,HATPase_c,HisKA,Methyltransf_11,Methyltransf_25,PAS_10,Response_reg
TLS3_k127_76045_7	1279009.ADICEAN_01286	2.026e-28	128.0	2AAU0@1|root,3106Q@2|Bacteria,4NNSV@976|Bacteroidetes,47Q0I@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_76045_8	927658.AJUM01000037_gene1987	1.2e-24	117.0	2AAU0@1|root,3106Q@2|Bacteria,4NNSV@976|Bacteroidetes,2G1MU@200643|Bacteroidia,3XISW@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_76045_2	1168289.AJKI01000002_gene2283	4.525e-81	277.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,2FM2C@200643|Bacteroidia,3XIXZ@558415|Marinilabiliaceae	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
TLS3_k127_76045_3	1408473.JHXO01000010_gene3567	1.386e-62	229.0	COG0450@1|root,COG0450@2|Bacteria,4PMJ6@976|Bacteroidetes,2G0D3@200643|Bacteroidia	976|Bacteroidetes	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
TLS3_k127_76045_4	1124780.ANNU01000032_gene1248	4.417e-61	226.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47JZP@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
TLS3_k127_76045_0	709991.Odosp_0293	1.745e-233	739.0	COG3408@1|root,COG3408@2|Bacteria,4NF09@976|Bacteroidetes,2FMEX@200643|Bacteroidia,22X3H@171551|Porphyromonadaceae	976|Bacteroidetes	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
TLS3_k127_76045_1	869213.JCM21142_52278	6.405e-201	632.0	COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,47JA2@768503|Cytophagia	976|Bacteroidetes	G	Starch synthase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
TLS3_k127_76045_9	927658.AJUM01000034_gene240	1.136e-18	85.0	COG1449@1|root,COG1449@2|Bacteria,4NFXW@976|Bacteroidetes,2FMRY@200643|Bacteroidia,3XJQV@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 57	amyA	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
TLS3_k127_7607979_3	929562.Emtol_3329	1.832e-23	100.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,47JY5@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
TLS3_k127_7607979_1	869213.JCM21142_72927	8.259e-131	436.0	28JDJ@1|root,2Z97V@2|Bacteria,4NJ02@976|Bacteroidetes,47UW0@768503|Cytophagia	976|Bacteroidetes	S	Capsule assembly protein Wzi	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
TLS3_k127_7607979_2	485917.Phep_3892	1.495e-33	136.0	COG0250@1|root,COG0250@2|Bacteria,4NSVU@976|Bacteroidetes,1ITZ8@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
TLS3_k127_7607979_0	313603.FB2170_05115	8.306e-141	473.0	COG3119@1|root,COG3119@2|Bacteria,4NE9D@976|Bacteroidetes,1HY4G@117743|Flavobacteriia,2PGRW@252356|Maribacter	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TLS3_k127_7631456_12	1077285.AGDG01000020_gene794	1.085e-52	193.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,2FMCR@200643|Bacteroidia,4AMYB@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
TLS3_k127_7631456_4	1235803.C825_00789	5.094e-136	440.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,2FMZE@200643|Bacteroidia,22WC5@171551|Porphyromonadaceae	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
TLS3_k127_7631456_1	886379.AEWI01000037_gene2949	7.715e-177	565.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,2FM6X@200643|Bacteroidia,3XJIV@558415|Marinilabiliaceae	976|Bacteroidetes	IM	FabA-like domain	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
TLS3_k127_7631456_8	714943.Mucpa_2748	7.313e-98	325.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,1IQ6Z@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
TLS3_k127_7631456_6	880074.BARVI_04050	3.575e-124	406.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,2FN7K@200643|Bacteroidia,22VV5@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
TLS3_k127_7631456_13	869213.JCM21142_104119	1.662e-51	184.0	COG3304@1|root,COG3304@2|Bacteria,4NQSS@976|Bacteroidetes,47RAQ@768503|Cytophagia	976|Bacteroidetes	S	Inner membrane component domain	-	-	-	-	-	-	-	-	-	-	-	-	YccF
TLS3_k127_7631456_3	595494.Tola_2337	2.433e-154	502.0	COG1055@1|root,COG1055@2|Bacteria	2|Bacteria	P	arsenite transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
TLS3_k127_7631456_0	869213.JCM21142_52267	1.188e-261	811.0	COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,47JZJ@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM FeS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
TLS3_k127_7631456_7	679937.Bcop_0284	5.554e-120	389.0	COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes,2FMCD@200643|Bacteroidia,4AM18@815|Bacteroidaceae	976|Bacteroidetes	O	COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
TLS3_k127_7631456_5	1408473.JHXO01000001_gene2375	5.352e-135	443.0	COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,2FNCN@200643|Bacteroidia	976|Bacteroidetes	O	FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
TLS3_k127_7631456_2	742727.HMPREF9447_02111	5.392e-167	534.0	COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,2FPF8@200643|Bacteroidia,4AN2M@815|Bacteroidaceae	976|Bacteroidetes	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
TLS3_k127_7631456_11	742725.HMPREF9450_01687	4.221e-53	190.0	COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,2FSRV@200643|Bacteroidia,22UGD@171550|Rikenellaceae	976|Bacteroidetes	S	Fe-S metabolism associated domain	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
TLS3_k127_7631456_14	742767.HMPREF9456_02002	3.711e-37	143.0	COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,2FT2N@200643|Bacteroidia,22Y47@171551|Porphyromonadaceae	976|Bacteroidetes	S	FeS assembly SUF system protein	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
TLS3_k127_7631456_9	1408473.JHXO01000001_gene2379	1.654e-79	275.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,2FPCB@200643|Bacteroidia	976|Bacteroidetes	C	iron-sulfur cluster-binding protein	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
TLS3_k127_7631456_10	1408473.JHXO01000005_gene1861	3.246e-55	196.0	COG0432@1|root,COG0432@2|Bacteria,4NUS2@976|Bacteroidetes,2FW13@200643|Bacteroidia	976|Bacteroidetes	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
TLS3_k127_7631456_15	1121100.JCM6294_3003	4.451e-28	120.0	COG1595@1|root,COG1595@2|Bacteria,4NQW2@976|Bacteroidetes,2FREW@200643|Bacteroidia,4APP7@815|Bacteroidaceae	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_7631456_16	709991.Odosp_1784	4.813e-09	68.0	2D9Y9@1|root,32TU8@2|Bacteria,4NT8A@976|Bacteroidetes,2FPKI@200643|Bacteroidia,22YRX@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7650071_2	338966.Ppro_3531	3.733e-100	347.0	COG1009@1|root,COG1009@2|Bacteria,1QV11@1224|Proteobacteria,43CGR@68525|delta/epsilon subdivisions,2X7RW@28221|Deltaproteobacteria	1224|Proteobacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
TLS3_k127_7650071_11	1279009.ADICEAN_03034	1.204e-12	75.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,47M8Q@768503|Cytophagia	976|Bacteroidetes	CP	NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit	mrpA	-	1.6.5.3	ko:K00341,ko:K05565	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	DUF4040,Proton_antipo_M,Proton_antipo_N
TLS3_k127_7650071_9	660470.Theba_1800	1.73e-17	87.0	COG2111@1|root,COG2111@2|Bacteria,2GCRE@200918|Thermotogae	200918|Thermotogae	P	Na H antiporter	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MnhB
TLS3_k127_7650071_7	521045.Kole_0566	1.891e-25	109.0	COG1006@1|root,COG1006@2|Bacteria,2GDBG@200918|Thermotogae	200918|Thermotogae	P	oxidoreductase, chain 4L	-	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
TLS3_k127_7650071_1	521045.Kole_0565	1.206e-105	361.0	COG0651@1|root,COG0651@2|Bacteria,2GE49@200918|Thermotogae	200918|Thermotogae	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
TLS3_k127_7650071_5	673860.AciM339_0655	3.695e-38	149.0	COG1863@1|root,arCOG03099@2157|Archaea,2XTHH@28890|Euryarchaeota,3F327@33867|unclassified Euryarchaeota	28890|Euryarchaeota	P	Na H ion antiporter subunit	phaE	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
TLS3_k127_7650071_12	1197130.BAFM01000019_gene2761	1.486e-11	68.0	COG2212@1|root,arCOG03121@2157|Archaea,2XZ7H@28890|Euryarchaeota,23WVH@183963|Halobacteria	183963|Halobacteria	P	Multiple resistance and pH regulation protein F	mrpF	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
TLS3_k127_7650071_8	521045.Kole_0562	9.341e-22	99.0	COG1320@1|root,COG1320@2|Bacteria	2|Bacteria	P	monovalent cation:proton antiporter activity	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
TLS3_k127_7650071_4	521045.Kole_0561	2.737e-38	151.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	ko:K12143	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Flavodoxin_5
TLS3_k127_7650071_10	1304875.JAFZ01000002_gene222	8.796e-14	77.0	COG0680@1|root,COG0680@2|Bacteria,3TBIR@508458|Synergistetes	508458|Synergistetes	C	hydrogenase maturation protease	-	-	3.4.23.51	ko:K08315	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
TLS3_k127_7650071_3	1168034.FH5T_12950	5.563e-54	213.0	COG2972@1|root,COG2972@2|Bacteria,4NGA0@976|Bacteroidetes	976|Bacteroidetes	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_7650071_6	1168034.FH5T_12955	1.34e-28	124.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,2FN7I@200643|Bacteroidia	976|Bacteroidetes	T	COG3279 Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_7650071_0	1349822.NSB1T_03650	1.353e-273	852.0	COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,2FN0P@200643|Bacteroidia,22WF7@171551|Porphyromonadaceae	976|Bacteroidetes	G	Belongs to the transketolase family	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
TLS3_k127_7652264_2	1209989.TepiRe1_1812	9.283e-46	169.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,42FBV@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
TLS3_k127_7652264_0	1408473.JHXO01000001_gene2036	1.803e-225	721.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,2FS4M@200643|Bacteroidia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_7652264_1	857087.Metme_3901	3.266e-142	488.0	COG2202@1|root,COG4251@1|root,COG5278@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,COG5278@2|Bacteria,1NWNJ@1224|Proteobacteria,1T2K7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Phosphonate-bd
TLS3_k127_7652264_3	1408473.JHXO01000002_gene3907	3.128e-43	168.0	COG4704@1|root,COG5492@1|root,COG4704@2|Bacteria,COG5492@2|Bacteria,4PI6E@976|Bacteroidetes,2FVYF@200643|Bacteroidia	976|Bacteroidetes	N	Fibrobacter succinogenes major domain (Fib_succ_major)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Fib_succ_major
TLS3_k127_7652584_3	1185876.BN8_04122	2.248e-83	284.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,47M5M@768503|Cytophagia	976|Bacteroidetes	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
TLS3_k127_7652584_1	1250232.JQNJ01000001_gene1562	9.486e-135	438.0	COG3693@1|root,COG3693@2|Bacteria,4NE5Z@976|Bacteroidetes,1HYNP@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_10
TLS3_k127_7652584_0	509635.N824_15670	6.4e-159	511.0	COG3828@1|root,COG3828@2|Bacteria,4NEWH@976|Bacteroidetes,1IR1M@117747|Sphingobacteriia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
TLS3_k127_7652584_2	761193.Runsl_2557	1.997e-133	430.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_7653263_2	869213.JCM21142_41757	5.31e-11	63.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,47PND@768503|Cytophagia	976|Bacteroidetes	M	Cell wall-associated hydrolase (invasion-associated protein)	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
TLS3_k127_7653263_0	760192.Halhy_4806	1.533e-125	418.0	COG3193@1|root,COG3193@2|Bacteria,4NHFF@976|Bacteroidetes,1INWG@117747|Sphingobacteriia	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_7653263_1	929703.KE386491_gene637	1.208e-27	113.0	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,4NDXS@976|Bacteroidetes,47YKE@768503|Cytophagia	976|Bacteroidetes	HP	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_76538_2	927658.AJUM01000040_gene941	4.064e-101	339.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,2G2TX@200643|Bacteroidia,3XJ1Z@558415|Marinilabiliaceae	976|Bacteroidetes	E	Amino acid kinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
TLS3_k127_76538_0	1124780.ANNU01000018_gene1648	1.239e-179	572.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,47JPG@768503|Cytophagia	976|Bacteroidetes	F	TIGRFAM dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
TLS3_k127_76538_1	385682.AFSL01000082_gene1163	7.967e-108	354.0	COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes,2FM3A@200643|Bacteroidia,3XIPG@558415|Marinilabiliaceae	976|Bacteroidetes	S	Glycosyltransferase like family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
TLS3_k127_7656369_0	697281.Mahau_2746	1.124e-167	539.0	COG5520@1|root,COG5520@2|Bacteria	2|Bacteria	M	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.136,3.2.1.55,3.2.1.8	ko:K01181,ko:K15921,ko:K15924	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM6,GH43,GH5	-	Beta_helix,Binary_toxB_2,Binary_toxB_3,CBM_6,CW_binding_1,Dockerin_1,Glyco_hydro_10,Glyco_hydro_30,Glyco_hydro_30C,Glyco_hydro_43,Lipase_GDSL_2,RicinB_lectin_2,Ricin_B_lectin
TLS3_k127_7656369_2	926549.KI421517_gene2437	3.517e-118	395.0	COG2610@1|root,COG2610@2|Bacteria,4NFBD@976|Bacteroidetes,47KJN@768503|Cytophagia	976|Bacteroidetes	EG	TIGRFAM gluconate transporter	-	-	-	ko:K06155,ko:K06157	-	-	-	-	ko00000,ko02000	2.A.8.1.2,2.A.8.1.4	-	-	GntP_permease
TLS3_k127_7656369_1	1121904.ARBP01000055_gene492	2.512e-127	416.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2,DDE_Tnp_1_4
TLS3_k127_7656369_3	1123248.KB893342_gene843	1.111e-54	199.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1IP8E@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
TLS3_k127_7663807_1	1408473.JHXO01000008_gene2677	2.466e-57	204.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
TLS3_k127_7663807_0	1131812.JQMS01000001_gene2382	6.663e-84	293.0	COG0845@1|root,COG0845@2|Bacteria,4NI7Q@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7663807_2	1124780.ANNU01000013_gene3827	1.914e-14	79.0	COG1917@1|root,COG1917@2|Bacteria,4PC6H@976|Bacteroidetes,47WW5@768503|Cytophagia	976|Bacteroidetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7663807_3	1454007.JAUG01000048_gene1937	7.094e-11	67.0	2CFVU@1|root,3373K@2|Bacteria,4NY6U@976|Bacteroidetes,1ITZA@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7663807_4	1408473.JHXO01000008_gene2661	7.796e-05	47.0	COG3237@1|root,COG3237@2|Bacteria,4NUMZ@976|Bacteroidetes,2FW1I@200643|Bacteroidia	976|Bacteroidetes	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
TLS3_k127_7692868_3	585543.HMPREF0969_02670	4.245e-137	446.0	COG3386@1|root,COG3386@2|Bacteria,4PMW0@976|Bacteroidetes,2FW62@200643|Bacteroidia,4AT1W@815|Bacteroidaceae	976|Bacteroidetes	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3,SGL
TLS3_k127_7692868_4	1129794.C427_4829	6.491e-132	433.0	COG3250@1|root,COG3250@2|Bacteria,1R8R6@1224|Proteobacteria,1RZM7@1236|Gammaproteobacteria,4660T@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C
TLS3_k127_7692868_0	1122931.AUAE01000007_gene1342	1.254e-228	746.0	COG0457@1|root,COG0457@2|Bacteria,4NKMF@976|Bacteroidetes,2FXC5@200643|Bacteroidia,231HD@171551|Porphyromonadaceae	1122931.AUAE01000007_gene1342|-	S	Domain of unknown function (DUF5107)	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7692868_2	234267.Acid_0198	1.34e-157	524.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,DUF3298,DUF4163,Glyco_hydro_9,Polysacc_deac_1
TLS3_k127_7692868_1	1168034.FH5T_15840	4.154e-209	660.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,2FNPT@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
TLS3_k127_7692868_5	742726.HMPREF9448_01035	1.454e-75	257.0	COG1874@1|root,COG1874@2|Bacteria,4PNM8@976|Bacteroidetes,2G105@200643|Bacteroidia,22YWU@171551|Porphyromonadaceae	976|Bacteroidetes	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7728462_0	1408473.JHXO01000010_gene3625	0.0	1035.0	COG0243@1|root,COG0243@2|Bacteria,4NITD@976|Bacteroidetes	976|Bacteroidetes	C	Molybdopterin oxidoreductase	-	-	1.7.2.3,1.8.5.5	ko:K07812,ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.4,5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
TLS3_k127_7728462_1	1250005.PHEL85_2142	5.975e-99	324.0	COG0437@1|root,COG0437@2|Bacteria,4NK7Y@976|Bacteroidetes,1I0UN@117743|Flavobacteriia	976|Bacteroidetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
TLS3_k127_7730508_0	1086011.HJ01_00930	1.335e-214	675.0	COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,1HX9V@117743|Flavobacteriia,2NSRH@237|Flavobacterium	976|Bacteroidetes	E	Prolyl oligopeptidase	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
TLS3_k127_7730508_5	1048983.EL17_13260	1.304e-52	189.0	2DM4T@1|root,31QCU@2|Bacteria,4PK44@976|Bacteroidetes,47QH5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7730508_2	742766.HMPREF9455_02467	1.287e-197	621.0	COG4733@1|root,COG4733@2|Bacteria,4PMVV@976|Bacteroidetes,2G0IK@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
TLS3_k127_7730508_6	385682.AFSL01000088_gene861	2.834e-37	143.0	COG5646@1|root,COG5646@2|Bacteria,4P9D6@976|Bacteroidetes,2G1H9@200643|Bacteroidia,3XKZW@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_7730508_1	1123008.KB905708_gene1024	1.533e-203	641.0	COG0673@1|root,COG0673@2|Bacteria,4NF9M@976|Bacteroidetes,2FP2F@200643|Bacteroidia,22ZHX@171551|Porphyromonadaceae	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
TLS3_k127_7730508_4	742725.HMPREF9450_00906	9.457e-86	293.0	COG1082@1|root,COG1082@2|Bacteria,4NFS5@976|Bacteroidetes,2FXP7@200643|Bacteroidia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
TLS3_k127_7730508_3	1123248.KB893359_gene1998	2.164e-119	393.0	COG4354@1|root,COG4354@2|Bacteria,4NFQW@976|Bacteroidetes,1IR0K@117747|Sphingobacteriia	976|Bacteroidetes	G	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term	-	-	3.2.1.45	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH116	-	DUF608,Glyco_hydr_116N
TLS3_k127_7735965_3	700598.Niako_6609	4.43e-108	364.0	COG2610@1|root,COG2610@2|Bacteria,4NFQH@976|Bacteroidetes,1IQKX@117747|Sphingobacteriia	976|Bacteroidetes	EG	COGs COG2610 H gluconate symporter and related permease	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
TLS3_k127_7735965_2	1123008.KB905695_gene2412	1.239e-134	443.0	COG2379@1|root,COG2379@2|Bacteria,4NI08@976|Bacteroidetes	976|Bacteroidetes	G	Hydroxypyruvate reductase	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
TLS3_k127_7735965_1	1123057.P872_17550	1.358e-135	441.0	COG1063@1|root,COG1063@2|Bacteria,4NJW8@976|Bacteroidetes,47M9A@768503|Cytophagia	976|Bacteroidetes	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_7735965_0	1123057.P872_17545	2.488e-161	515.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,47ME7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_7752653_3	760192.Halhy_1044	2.419e-38	158.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IPTQ@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
TLS3_k127_7752653_6	1123288.SOV_3c08010	2.243e-07	63.0	2E676@1|root,330VQ@2|Bacteria,1VCQS@1239|Firmicutes,4H6V2@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7752653_5	1250005.PHEL85_0209	6.748e-19	93.0	2E6Q3@1|root,331AC@2|Bacteria,4NUP2@976|Bacteroidetes,1I66X@117743|Flavobacteriia,3VWRC@52959|Polaribacter	976|Bacteroidetes	S	Family of unknown function (DUF5362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5362
TLS3_k127_7752653_0	649349.Lbys_0715	3.999e-114	377.0	COG0793@1|root,COG0793@2|Bacteria,4NFEN@976|Bacteroidetes,47PTG@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Tricorn_C1
TLS3_k127_7752653_1	1239962.C943_02871	3.008e-44	166.0	COG1525@1|root,COG1525@2|Bacteria,4NT3S@976|Bacteroidetes,47RZB@768503|Cytophagia	976|Bacteroidetes	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
TLS3_k127_7752653_4	1343739.PAP_00900	2.239e-21	97.0	COG1917@1|root,arCOG02994@2157|Archaea,2XZAN@28890|Euryarchaeota,2446X@183968|Thermococci	183968|Thermococci	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_7777408_7	1288963.ADIS_1121	1.374e-16	82.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,47JGM@768503|Cytophagia	976|Bacteroidetes	G	COGs COG2133 Glucose sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
TLS3_k127_7777408_3	1408473.JHXO01000005_gene1864	3.828e-77	278.0	2919D@1|root,2ZNWG@2|Bacteria,4NMU5@976|Bacteroidetes,2FW6F@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7777408_2	313603.FB2170_14818	6.925e-86	296.0	COG0484@1|root,COG0484@2|Bacteria,4NPS0@976|Bacteroidetes	976|Bacteroidetes	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7777408_0	694427.Palpr_0869	2.23e-183	589.0	COG0484@1|root,COG0484@2|Bacteria,4P0AH@976|Bacteroidetes,2FYI2@200643|Bacteroidia	976|Bacteroidetes	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7777408_1	694427.Palpr_0868	2.032e-147	482.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,4NDVS@976|Bacteroidetes,2FWNG@200643|Bacteroidia	976|Bacteroidetes	CO	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Pyr_redox_3
TLS3_k127_7777408_4	694427.Palpr_0867	8.38e-56	203.0	COG0492@1|root,COG0492@2|Bacteria,4NNAA@976|Bacteroidetes,2FXF6@200643|Bacteroidia	976|Bacteroidetes	O	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7777408_5	1408433.JHXV01000015_gene1734	7.515e-53	204.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,4P03T@976|Bacteroidetes	976|Bacteroidetes	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
TLS3_k127_7777408_6	521011.Mpal_0668	1.374e-21	109.0	arCOG08079@1|root,arCOG08079@2157|Archaea,2Y2VZ@28890|Euryarchaeota,2NB3K@224756|Methanomicrobia	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA
TLS3_k127_7780149_0	1408473.JHXO01000008_gene2837	3.346e-260	816.0	COG0348@1|root,COG1622@1|root,COG0348@2|Bacteria,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	vnfA	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,Fer4_5,Sigma54_activat,cNMP_binding
TLS3_k127_7780149_1	927658.AJUM01000022_gene1031	3.595e-198	621.0	COG0524@1|root,COG0524@2|Bacteria,4NH8K@976|Bacteroidetes,2FM8P@200643|Bacteroidia,3XIZT@558415|Marinilabiliaceae	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
TLS3_k127_7780149_2	1168034.FH5T_02855	1.186e-100	339.0	COG0842@1|root,COG0842@2|Bacteria,4NFM0@976|Bacteroidetes,2FMNV@200643|Bacteroidia	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
TLS3_k127_7780149_3	290512.Paes_1107	5.644e-05	45.0	COG0842@1|root,COG0842@2|Bacteria,1FD8A@1090|Chlorobi	1090|Chlorobi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
TLS3_k127_7799241_0	1120968.AUBX01000011_gene3366	8.224e-134	444.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,47JP2@768503|Cytophagia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
TLS3_k127_7799241_3	1168289.AJKI01000011_gene490	1.061e-68	241.0	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,2FT0I@200643|Bacteroidia,3XJNI@558415|Marinilabiliaceae	976|Bacteroidetes	I	PcrB family	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
TLS3_k127_7799241_7	1121101.HMPREF1532_02770	1.678e-37	152.0	COG2091@1|root,COG2091@2|Bacteria,4NSBI@976|Bacteroidetes,2FN3N@200643|Bacteroidia,4ANG4@815|Bacteroidaceae	976|Bacteroidetes	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	-	-	-	-	-	-	-	-	-	ACPS
TLS3_k127_7799241_4	927658.AJUM01000037_gene2367	7.544e-52	190.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,2FUEE@200643|Bacteroidia,3XK52@558415|Marinilabiliaceae	976|Bacteroidetes	S	Gliding motility-associated lipoprotein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7799241_1	926562.Oweho_3003	8.704e-102	346.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1HXF3@117743|Flavobacteriia,2PABH@246874|Cryomorphaceae	976|Bacteroidetes	S	Transporter associated domain	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
TLS3_k127_7799241_5	1408473.JHXO01000005_gene1506	3.554e-45	168.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,2FT5G@200643|Bacteroidia	976|Bacteroidetes	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
TLS3_k127_7799241_6	385682.AFSL01000026_gene635	1.259e-43	160.0	COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,2FTUV@200643|Bacteroidia,3XKAF@558415|Marinilabiliaceae	976|Bacteroidetes	L	bacterial (prokaryotic) histone like domain	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
TLS3_k127_7799241_8	714943.Mucpa_2551	2.304e-06	49.0	2EIUI@1|root,33CJV@2|Bacteria,4NYR6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7799241_2	1408473.JHXO01000005_gene1509	1.141e-72	248.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,2FMXV@200643|Bacteroidia	976|Bacteroidetes	J	S1 RNA binding domain protein	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
TLS3_k127_7812352_3	1123248.KB893318_gene4146	1.2e-57	208.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,1IPQ2@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
TLS3_k127_7812352_0	1121129.KB903359_gene1821	1.054e-184	590.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,2FNG7@200643|Bacteroidia,22XCZ@171551|Porphyromonadaceae	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
TLS3_k127_7812352_1	1408473.JHXO01000004_gene118	1.147e-159	535.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,2FMUB@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG25960 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_7812352_2	1121100.JCM6294_1298	1.345e-92	309.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,2FMU1@200643|Bacteroidia,4AMSW@815|Bacteroidaceae	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
TLS3_k127_7812352_4	1168034.FH5T_12480	4.982e-07	60.0	2EKSY@1|root,33EGP@2|Bacteria,4NXJC@976|Bacteroidetes,2FVKV@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG23390 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7815363_6	1408473.JHXO01000011_gene3096	2.006e-86	293.0	COG3568@1|root,COG3568@2|Bacteria,4NHXV@976|Bacteroidetes,2FNR3@200643|Bacteroidia	976|Bacteroidetes	S	Endonuclease exonuclease phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_7815363_4	1288963.ADIS_0044	1.074e-110	367.0	COG1735@1|root,COG1735@2|Bacteria,4NJYF@976|Bacteroidetes,47NZQ@768503|Cytophagia	976|Bacteroidetes	S	Phosphotriesterase family	php	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
TLS3_k127_7815363_0	700598.Niako_5372	0.0	1036.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1IQN2@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
TLS3_k127_7815363_1	1120965.AUBV01000010_gene2723	5.035e-209	657.0	COG0673@1|root,COG0673@2|Bacteria,4NHDS@976|Bacteroidetes,47K92@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_7815363_5	1120966.AUBU01000002_gene1962	6.05e-102	343.0	2DBNR@1|root,2ZA54@2|Bacteria,4NHW9@976|Bacteroidetes,47Y9I@768503|Cytophagia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
TLS3_k127_7815363_7	1121481.AUAS01000014_gene2341	3.415e-74	258.0	28J3W@1|root,2Z900@2|Bacteria,4NG4R@976|Bacteroidetes,47NT0@768503|Cytophagia	976|Bacteroidetes	S	pfam nipsnap	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
TLS3_k127_7815363_2	1453500.AT05_07140	4.441e-202	637.0	COG1350@1|root,COG1350@2|Bacteria,4PKSY@976|Bacteroidetes,1IK1C@117743|Flavobacteriia	976|Bacteroidetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_7815363_3	1211813.CAPH01000009_gene67	5.542e-119	395.0	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,2FNY8@200643|Bacteroidia,22U88@171550|Rikenellaceae	976|Bacteroidetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
TLS3_k127_7815363_8	1122226.AUHX01000004_gene1905	2.585e-24	104.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1HX6I@117743|Flavobacteriia	976|Bacteroidetes	E	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
TLS3_k127_7816196_7	1110502.TMO_1478	8.127e-07	56.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MVYW@1224|Proteobacteria,2TS8D@28211|Alphaproteobacteria,2JVKC@204441|Rhodospirillales	204441|Rhodospirillales	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cytochrom_C,Cytochrome_CBB3
TLS3_k127_7816196_5	1121405.dsmv_0440	4.809e-13	71.0	2E9C8@1|root,333JY@2|Bacteria,1PAR4@1224|Proteobacteria,432FD@68525|delta/epsilon subdivisions,2WY2S@28221|Deltaproteobacteria,2MP8E@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7816196_0	926562.Oweho_2461	2.251e-131	433.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1HXU8@117743|Flavobacteriia,2PBJK@246874|Cryomorphaceae	976|Bacteroidetes	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
TLS3_k127_7816196_1	760192.Halhy_1877	5.249e-81	275.0	COG0135@1|root,COG0135@2|Bacteria,4NK5D@976|Bacteroidetes,1IYYF@117747|Sphingobacteriia	976|Bacteroidetes	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	-	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
TLS3_k127_7816196_2	877418.ATWV01000006_gene2092	1.265e-57	205.0	COG1502@1|root,COG1502@2|Bacteria,2JA89@203691|Spirochaetes	203691|Spirochaetes	I	Phospholipase D Active site motif	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
TLS3_k127_7816196_4	1379270.AUXF01000001_gene2135	6.819e-20	96.0	COG3871@1|root,COG3871@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	ydaG	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Putative_PNPOx,Pyrid_ox_like
TLS3_k127_7816196_6	635013.TherJR_0673	9.499e-13	70.0	COG3478@1|root,COG3478@2|Bacteria,1VIG4@1239|Firmicutes,25DD7@186801|Clostridia,26629@186807|Peptococcaceae	186801|Clostridia	S	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7816196_3	1459636.NTE_00038	9.69e-44	163.0	COG0346@1|root,arCOG02708@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS3_k127_7832105_0	485917.Phep_3395	2.872e-122	401.0	COG3940@1|root,COG3940@2|Bacteria,4NGA6@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	BACON,Glyco_hydro_43
TLS3_k127_7832105_1	1121129.KB903371_gene175	3.062e-103	347.0	COG0392@1|root,COG0392@2|Bacteria,4NIWG@976|Bacteroidetes,2FN20@200643|Bacteroidia,22W97@171551|Porphyromonadaceae	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
TLS3_k127_7832105_2	385682.AFSL01000008_gene2589	4.51e-99	345.0	COG1131@1|root,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,2FRF1@200643|Bacteroidia,3XIPC@558415|Marinilabiliaceae	976|Bacteroidetes	V	Tellurite resistance protein TerB	-	-	-	ko:K21397	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,TerB
TLS3_k127_7832105_3	1168034.FH5T_07395	3.687e-14	80.0	2EUJZ@1|root,33N1X@2|Bacteria,4NYSW@976|Bacteroidetes,2FVUM@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7843393_9	679199.HMPREF9332_01296	4.315e-28	117.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,2FM93@200643|Bacteroidia,1WD1Q@1283313|Alloprevotella	976|Bacteroidetes	D	Cell cycle protein	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
TLS3_k127_7843393_3	1122931.AUAE01000012_gene2271	5.725e-131	428.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,2FMND@200643|Bacteroidia,22X87@171551|Porphyromonadaceae	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
TLS3_k127_7843393_2	714943.Mucpa_1521	9.847e-137	449.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1INTF@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_7843393_8	743722.Sph21_0054	8.363e-42	163.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,1IRV2@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
TLS3_k127_7843393_0	869213.JCM21142_31299	8.797e-145	472.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,47K6I@768503|Cytophagia	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
TLS3_k127_7843393_1	869213.JCM21142_31300	4.602e-137	451.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,47MUN@768503|Cytophagia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
TLS3_k127_7843393_6	694427.Palpr_0191	1.468e-85	308.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,2FNYT@200643|Bacteroidia,22W3I@171551|Porphyromonadaceae	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
TLS3_k127_7843393_5	385682.AFSL01000053_gene472	7.384e-116	390.0	COG4623@1|root,COG4623@2|Bacteria,4NHFW@976|Bacteroidetes,2FN2R@200643|Bacteroidia,3XJUD@558415|Marinilabiliaceae	976|Bacteroidetes	M	Bacterial periplasmic substrate-binding proteins	mltF	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
TLS3_k127_7843393_7	1089547.KB913013_gene3664	3.172e-42	162.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,47MQZ@768503|Cytophagia	976|Bacteroidetes	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_7843393_4	1408473.JHXO01000011_gene2957	3.263e-122	401.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,2FMHC@200643|Bacteroidia	976|Bacteroidetes	M	Efflux ABC transporter, permease protein	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
TLS3_k127_7843632_0	1229487.AMYW01000030_gene3641	1.106e-310	967.0	COG3345@1|root,COG3345@2|Bacteria,4NHAT@976|Bacteroidetes,1I8DT@117743|Flavobacteriia,2NUNI@237|Flavobacterium	976|Bacteroidetes	G	Glycosyl hydrolase family 36 N-terminal domain	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
TLS3_k127_7843632_8	1168034.FH5T_13190	7.281e-54	192.0	COG1225@1|root,COG1225@2|Bacteria,4NXEC@976|Bacteroidetes,2FZPP@200643|Bacteroidia	976|Bacteroidetes	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7843632_5	1442599.JAAN01000002_gene2186	2.395e-128	422.0	COG3866@1|root,COG3866@2|Bacteria,1MUT3@1224|Proteobacteria,1RT2J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Pectate lyase	pelZ	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TLS3_k127_7843632_1	641524.ADICYQ_4144	2.15e-262	827.0	COG0475@1|root,COG0475@2|Bacteria,4NF11@976|Bacteroidetes,47KD1@768503|Cytophagia	976|Bacteroidetes	P	Sodium/hydrogen exchanger family	ybaL_1	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
TLS3_k127_7843632_4	869213.JCM21142_72989	2.441e-153	497.0	COG1232@1|root,COG1232@2|Bacteria,4NH1E@976|Bacteroidetes,47K84@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
TLS3_k127_7843632_6	869213.JCM21142_72988	1.245e-107	359.0	COG0276@1|root,COG0276@2|Bacteria,4NE83@976|Bacteroidetes,47JH0@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
TLS3_k127_7843632_3	999419.HMPREF1077_02032	4.583e-163	519.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,2FMYA@200643|Bacteroidia,22X1K@171551|Porphyromonadaceae	976|Bacteroidetes	S	2-nitropropane dioxygenase	-	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
TLS3_k127_7843632_2	667015.Bacsa_2116	2.249e-213	676.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,2FMB6@200643|Bacteroidia,4AKQ6@815|Bacteroidaceae	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
TLS3_k127_7843632_7	1124780.ANNU01000016_gene1870	1.225e-60	212.0	COG1105@1|root,COG1105@2|Bacteria,4NFZI@976|Bacteroidetes,47MVA@768503|Cytophagia	976|Bacteroidetes	H	belongs to the carbohydrate kinase PfkB family	pfkB	-	2.7.1.11,2.7.1.144	ko:K00917,ko:K16370	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
TLS3_k127_7844037_0	385682.AFSL01000065_gene1629	0.0	1810.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,3XJQ5@558415|Marinilabiliaceae	976|Bacteroidetes	C	Domain of unknown function	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
TLS3_k127_7844037_1	742817.HMPREF9449_01282	1.926e-217	693.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,2FN7R@200643|Bacteroidia,22X21@171551|Porphyromonadaceae	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
TLS3_k127_7844037_2	927658.AJUM01000042_gene1460	9.687e-128	413.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,2FWAQ@200643|Bacteroidia,3XJHZ@558415|Marinilabiliaceae	976|Bacteroidetes	K	Sigma-70 region 3	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS3_k127_7844037_3	1229276.DI53_0098	4.403e-87	292.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,1IPVS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
TLS3_k127_7844037_4	1218108.KB908291_gene682	3.825e-35	136.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,1HXKT@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
TLS3_k127_784803_3	926549.KI421517_gene1509	1.467e-78	299.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,4PKPC@976|Bacteroidetes,47N8S@768503|Cytophagia	976|Bacteroidetes	DZ	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,RCC1
TLS3_k127_784803_4	1121904.ARBP01000024_gene6617	3.806e-54	202.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,47KE6@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_784803_2	869213.JCM21142_41900	6.063e-84	296.0	COG0823@1|root,COG2885@1|root,COG3291@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,COG3291@2|Bacteria,4NE6G@976|Bacteroidetes,47K1N@768503|Cytophagia	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,PKD
TLS3_k127_784803_1	385682.AFSL01000024_gene2062	1.218e-99	335.0	COG3291@1|root,COG3291@2|Bacteria,4NHJJ@976|Bacteroidetes,2G20Y@200643|Bacteroidia,3XJ8K@558415|Marinilabiliaceae	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_784803_0	927658.AJUM01000037_gene2297	2.479e-157	534.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NKGA@976|Bacteroidetes,2G0DG@200643|Bacteroidia,3XJHT@558415|Marinilabiliaceae	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,SpoIIE,Y_Y_Y
TLS3_k127_7860956_3	143224.JQMD01000002_gene3361	1.061e-10	62.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
TLS3_k127_7860956_2	926549.KI421517_gene78	7.687e-67	235.0	COG2159@1|root,COG2159@2|Bacteria,4NH6P@976|Bacteroidetes,47M0D@768503|Cytophagia	976|Bacteroidetes	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_7860956_0	247490.KSU1_B0663	0.0	1290.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,2J293@203682|Planctomycetes	203682|Planctomycetes	I	CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
TLS3_k127_7860956_1	616991.JPOO01000001_gene3038	4.339e-147	482.0	COG3540@1|root,COG3540@2|Bacteria,4NFXQ@976|Bacteroidetes,1HY2S@117743|Flavobacteriia,23I26@178469|Arenibacter	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
TLS3_k127_7862676_1	1168289.AJKI01000003_gene2916	3.064e-193	624.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,2FPNU@200643|Bacteroidia,3XIN1@558415|Marinilabiliaceae	976|Bacteroidetes	L	SNF2 family N-terminal domain	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N
TLS3_k127_7862676_0	886379.AEWI01000010_gene631	2.032e-281	874.0	COG1034@1|root,COG4624@1|root,COG1034@2|Bacteria,COG4624@2|Bacteria,4P26W@976|Bacteroidetes,2FXEU@200643|Bacteroidia,3XJ7H@558415|Marinilabiliaceae	976|Bacteroidetes	C	Iron hydrogenase small subunit	-	-	1.12.1.3	ko:K18332	-	-	-	-	ko00000,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4_9,NADH-G_4Fe-4S_3
TLS3_k127_7862676_2	1168289.AJKI01000021_gene1704	7.436e-169	540.0	COG1894@1|root,COG1894@2|Bacteria,4P09J@976|Bacteroidetes,2FXDI@200643|Bacteroidia,3XJ3K@558415|Marinilabiliaceae	976|Bacteroidetes	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S
TLS3_k127_7862676_4	1168034.FH5T_02915	5.729e-63	219.0	COG1905@1|root,COG1905@2|Bacteria,4NHIQ@976|Bacteroidetes,2FXUE@200643|Bacteroidia	976|Bacteroidetes	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
TLS3_k127_7862676_3	927658.AJUM01000037_gene1951	8.648e-119	393.0	COG5276@1|root,COG5276@2|Bacteria,4NG4W@976|Bacteroidetes,2FNZ8@200643|Bacteroidia,3XKCP@558415|Marinilabiliaceae	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
TLS3_k127_7865259_0	1408473.JHXO01000006_gene1341	0.0	1146.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
TLS3_k127_7865259_1	313606.M23134_08430	3.749e-74	257.0	COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,47XHY@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
TLS3_k127_7865259_2	385682.AFSL01000008_gene2527	1.029e-62	220.0	COG0009@1|root,COG0009@2|Bacteria,4NM43@976|Bacteroidetes,2FPW5@200643|Bacteroidia,3XK0I@558415|Marinilabiliaceae	976|Bacteroidetes	J	Telomere recombination	rimN	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
TLS3_k127_7865259_3	1279009.ADICEAN_01163	3.307e-34	141.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,47RJQ@768503|Cytophagia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
TLS3_k127_7880595_0	694427.Palpr_0224	1.761e-182	577.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,4NER2@976|Bacteroidetes,2FQ0E@200643|Bacteroidia	976|Bacteroidetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
TLS3_k127_7880595_2	694427.Palpr_1119	9.082e-22	108.0	COG1216@1|root,COG1216@2|Bacteria,4PCIG@976|Bacteroidetes,2FZZ9@200643|Bacteroidia	976|Bacteroidetes	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
TLS3_k127_7880595_1	395961.Cyan7425_4332	2.649e-139	462.0	COG1132@1|root,COG1132@2|Bacteria,1G0C0@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS3_k127_7880595_3	483218.BACPEC_00539	1.932e-08	61.0	COG0681@1|root,COG0681@2|Bacteria,1VFKY@1239|Firmicutes,24RQG@186801|Clostridia,269W4@186813|unclassified Clostridiales	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
TLS3_k127_7880595_4	927658.AJUM01000042_gene1723	3.975e-07	53.0	28RJ8@1|root,32TGW@2|Bacteria,4NSBX@976|Bacteroidetes,2G256@200643|Bacteroidia,3XJV9@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7903106_1	405948.SACE_4234	3.637e-25	124.0	COG1502@1|root,COG1502@2|Bacteria,2GN2V@201174|Actinobacteria,4E06F@85010|Pseudonocardiales	201174|Actinobacteria	I	Phospholipase D Active site motif	-	-	-	-	-	-	-	-	-	-	-	-	PLDc,PLDc_2
TLS3_k127_7903106_0	1121011.AUCB01000018_gene4088	3.86e-138	442.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR,PPC,Peptidase_S8
TLS3_k127_7915828_4	1123248.KB893315_gene3021	7.7e-29	120.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,1INN2@117747|Sphingobacteriia	976|Bacteroidetes	NU	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_7915828_1	1237149.C900_03750	1.03e-76	265.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,47JXK@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
TLS3_k127_7915828_3	385682.AFSL01000100_gene40	2.013e-49	185.0	2C52N@1|root,2Z7U1@2|Bacteria,4NEZW@976|Bacteroidetes,2FNRZ@200643|Bacteroidia,3XJ3D@558415|Marinilabiliaceae	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	porT	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_7915828_0	385682.AFSL01000100_gene39	2.379e-193	616.0	COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,2FM1G@200643|Bacteroidia,3XJ82@558415|Marinilabiliaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2
TLS3_k127_7915828_2	742726.HMPREF9448_00021	1.117e-62	224.0	COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,2FNE2@200643|Bacteroidia,22WK6@171551|Porphyromonadaceae	976|Bacteroidetes	J	RNA methyltransferase	aviRb	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
TLS3_k127_7915828_5	385682.AFSL01000100_gene37	4.339e-25	109.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,2FM1J@200643|Bacteroidia,3XJIH@558415|Marinilabiliaceae	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
TLS3_k127_791862_6	1123277.KB893176_gene3824	6.704e-26	109.0	COG1669@1|root,COG1669@2|Bacteria,4NVYQ@976|Bacteroidetes	976|Bacteroidetes	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
TLS3_k127_791862_5	349161.Dred_3118	8.781e-28	115.0	COG2361@1|root,COG2361@2|Bacteria,1VFEB@1239|Firmicutes,24QN5@186801|Clostridia,2635X@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
TLS3_k127_791862_8	1223410.KN050846_gene59	0.0006324	48.0	2DPR6@1|root,3331T@2|Bacteria,4NUQQ@976|Bacteroidetes,1I6W7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_791862_4	1408433.JHXV01000005_gene2462	7.999e-30	121.0	2E5WH@1|root,30K07@2|Bacteria,4P5HE@976|Bacteroidetes,1ICRB@117743|Flavobacteriia,2PBVH@246874|Cryomorphaceae	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
TLS3_k127_791862_2	886379.AEWI01000012_gene1079	1.339e-96	326.0	COG0524@1|root,COG0524@2|Bacteria,4NIHI@976|Bacteroidetes,2FPRJ@200643|Bacteroidia,3XIRP@558415|Marinilabiliaceae	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
TLS3_k127_791862_1	485918.Cpin_4672	2.792e-171	547.0	COG0673@1|root,COG0673@2|Bacteria,4NGGS@976|Bacteroidetes,1IQPN@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_791862_0	709991.Odosp_1648	4.507e-302	952.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,2FMCE@200643|Bacteroidia,22WW4@171551|Porphyromonadaceae	976|Bacteroidetes	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_791862_3	1168034.FH5T_03570	4.086e-93	308.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,2FSWC@200643|Bacteroidia	976|Bacteroidetes	F	Deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
TLS3_k127_7920693_2	411477.PARMER_03213	4.587e-64	222.0	COG4225@1|root,COG4225@2|Bacteria,4NDYS@976|Bacteroidetes,2FM61@200643|Bacteroidia,22XA8@171551|Porphyromonadaceae	976|Bacteroidetes	S	Glycosyl Hydrolase Family 88	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
TLS3_k127_7920693_0	485917.Phep_2693	1.189e-214	674.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1IVQ5@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
TLS3_k127_7920693_1	1235803.C825_03344	4.757e-199	628.0	COG0129@1|root,COG0129@2|Bacteria,4NFHP@976|Bacteroidetes,2FMCC@200643|Bacteroidia,22WXM@171551|Porphyromonadaceae	976|Bacteroidetes	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
TLS3_k127_7926104_0	1123008.KB905698_gene3480	1.514e-221	695.0	COG1966@1|root,COG1966@2|Bacteria,4NFPD@976|Bacteroidetes,2FM48@200643|Bacteroidia,22X1U@171551|Porphyromonadaceae	976|Bacteroidetes	T	Carbon starvation protein	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
TLS3_k127_7926104_1	1239962.C943_00881	5.488e-119	388.0	COG5297@1|root,COG5297@2|Bacteria,4NG19@976|Bacteroidetes	976|Bacteroidetes	G	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1593
TLS3_k127_7947249_2	1237149.C900_02914	1.542e-47	172.0	COG1028@1|root,COG1028@2|Bacteria,4NFTU@976|Bacteroidetes,47N90@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	fabG3	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_7947249_0	742727.HMPREF9447_04266	6.962e-181	573.0	COG0304@1|root,COG0304@2|Bacteria,4NFBN@976|Bacteroidetes,2FNHE@200643|Bacteroidia,4AM5N@815|Bacteroidaceae	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabB	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_7947249_4	1236508.BAKF01000007_gene855	2.05e-17	84.0	COG0236@1|root,COG0236@2|Bacteria,4NV57@976|Bacteroidetes,2FTTN@200643|Bacteroidia	976|Bacteroidetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TLS3_k127_7947249_1	485918.Cpin_1857	5.804e-92	310.0	COG4261@1|root,COG4261@2|Bacteria,4NF49@976|Bacteroidetes,1IT2S@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
TLS3_k127_7947249_3	1121878.AUGL01000002_gene2374	2.02e-28	119.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,1RPZX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
TLS3_k127_7955679_4	1121097.JCM15093_1319	1.272e-16	81.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,2FMHC@200643|Bacteroidia,4AKSB@815|Bacteroidaceae	976|Bacteroidetes	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
TLS3_k127_7955679_2	1120951.AUBG01000019_gene1716	8.665e-134	437.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1HWQT@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
TLS3_k127_7955679_1	385682.AFSL01000053_gene496	7.104e-192	604.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,2FN1B@200643|Bacteroidia,3XJVE@558415|Marinilabiliaceae	976|Bacteroidetes	E	Aminotransferase class I and II	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_7955679_3	459349.CLOAM0099	5.485e-50	191.0	COG2234@1|root,COG2234@2|Bacteria,2NQ2F@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M28	-	-	3.4.11.10	ko:K05994	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
TLS3_k127_7955679_0	385682.AFSL01000053_gene498	0.0	1263.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,2FPJG@200643|Bacteroidia,3XJ8Q@558415|Marinilabiliaceae	976|Bacteroidetes	J	Valyl tRNA synthetase tRNA binding arm	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
TLS3_k127_7958693_4	886379.AEWI01000002_gene534	2.695e-83	279.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,2FPIT@200643|Bacteroidia,3XISD@558415|Marinilabiliaceae	976|Bacteroidetes	U	SecY translocase	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
TLS3_k127_7958693_2	1501391.LG35_06825	1.166e-110	362.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,2FM24@200643|Bacteroidia,22U4M@171550|Rikenellaceae	976|Bacteroidetes	E	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
TLS3_k127_7958693_8	1168034.FH5T_12920	3.399e-40	149.0	COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,2FTSU@200643|Bacteroidia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
TLS3_k127_7958693_9	746697.Aeqsu_1929	4.927e-15	75.0	COG0257@1|root,COG0257@2|Bacteria,4NXGE@976|Bacteroidetes,1I6A2@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
TLS3_k127_7958693_7	1122621.ATZA01000014_gene3232	8.248e-57	200.0	COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,1ISH0@117747|Sphingobacteriia	976|Bacteroidetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
TLS3_k127_7958693_5	1408473.JHXO01000006_gene1305	3.844e-64	221.0	COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,2FRZD@200643|Bacteroidia	976|Bacteroidetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
TLS3_k127_7958693_3	1122931.AUAE01000024_gene3740	1.315e-97	321.0	COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,2FMRC@200643|Bacteroidia,22WPW@171551|Porphyromonadaceae	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
TLS3_k127_7958693_1	1168034.FH5T_12940	1.88e-169	537.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
TLS3_k127_7958693_6	926549.KI421517_gene236	4.061e-57	203.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,47PPE@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
TLS3_k127_7958693_0	742725.HMPREF9450_00084	1.767e-222	694.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,22U9M@171550|Rikenellaceae	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
TLS3_k127_7971831_0	1168034.FH5T_04685	7.126e-75	278.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,2FRVJ@200643|Bacteroidia	976|Bacteroidetes	T	COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_7991246_1	1121859.KB890750_gene256	3.083e-91	307.0	COG3408@1|root,COG3408@2|Bacteria,4NESP@976|Bacteroidetes,47J9V@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-rhamnosidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
TLS3_k127_7991246_0	880070.Cycma_2351	2.202e-300	938.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,47MPU@768503|Cytophagia	976|Bacteroidetes	G	glycoside hydrolase family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
TLS3_k127_8011076_5	869213.JCM21142_41686	3.335e-85	284.0	COG1014@1|root,COG1014@2|Bacteria,4NGWJ@976|Bacteroidetes	976|Bacteroidetes	C	2-oxoacid ferredoxin flavodoxin oxidoreductase, gamma subunit	porG	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
TLS3_k127_8011076_4	927658.AJUM01000042_gene1758	9.595e-127	409.0	COG1013@1|root,COG1013@2|Bacteria,4NDWF@976|Bacteroidetes,2FP3C@200643|Bacteroidia,3XJ0W@558415|Marinilabiliaceae	976|Bacteroidetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	vorA	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
TLS3_k127_8011076_3	927658.AJUM01000042_gene1757	3.863e-164	522.0	COG0674@1|root,COG0674@2|Bacteria,4NGYK@976|Bacteroidetes,2FM6R@200643|Bacteroidia,3XJ7J@558415|Marinilabiliaceae	976|Bacteroidetes	C	Pyruvate:ferredoxin oxidoreductase core domain II	vorB	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
TLS3_k127_8011076_10	1408473.JHXO01000004_gene255	8.165e-30	119.0	COG1146@1|root,COG1146@2|Bacteria,4NV91@976|Bacteroidetes,2FTXT@200643|Bacteroidia	976|Bacteroidetes	C	4Fe-4S binding domain protein	oorD	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_21,Fer4_4
TLS3_k127_8011076_2	945713.IALB_1428	1.631e-169	544.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	alaC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
TLS3_k127_8011076_1	927658.AJUM01000042_gene1754	1.987e-220	690.0	COG1541@1|root,COG1541@2|Bacteria,4NGRR@976|Bacteroidetes,2FNC4@200643|Bacteroidia,3XJ09@558415|Marinilabiliaceae	976|Bacteroidetes	H	AMP-binding enzyme C-terminal domain	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
TLS3_k127_8011076_9	927658.AJUM01000042_gene1753	7.626e-44	164.0	COG4747@1|root,COG4747@2|Bacteria,4NQIW@976|Bacteroidetes,2FS2U@200643|Bacteroidia,3XK6D@558415|Marinilabiliaceae	976|Bacteroidetes	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
TLS3_k127_8011076_0	1168289.AJKI01000006_gene241	7.491e-294	917.0	COG1042@1|root,COG1042@2|Bacteria,4NFTI@976|Bacteroidetes,2FNSJ@200643|Bacteroidia,3XJFP@558415|Marinilabiliaceae	976|Bacteroidetes	C	ATP-grasp domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
TLS3_k127_8011076_11	1144313.PMI10_00718	0.0005521	52.0	COG3386@1|root,COG3386@2|Bacteria,4PKCK@976|Bacteroidetes,1IJ7K@117743|Flavobacteriia,2P0KA@237|Flavobacterium	976|Bacteroidetes	G	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8011076_8	287986.DV20_26255	1.659e-65	243.0	COG4733@1|root,COG4733@2|Bacteria,2HJAB@201174|Actinobacteria,4E5P6@85010|Pseudonocardiales	201174|Actinobacteria	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_6
TLS3_k127_8011076_7	221288.JH992901_gene2459	2.113e-67	237.0	COG0454@1|root,COG0456@2|Bacteria,1GD5Y@1117|Cyanobacteria,1JHKK@1189|Stigonemataceae	1117|Cyanobacteria	K	GNAT acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
TLS3_k127_8011076_6	485918.Cpin_2807	6.905e-81	279.0	COG0265@1|root,COG0265@2|Bacteria,4NGRE@976|Bacteroidetes	976|Bacteroidetes	O	smart pdz dhr glgf	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
TLS3_k127_8045373_2	1408473.JHXO01000011_gene3175	2.501e-133	434.0	COG0111@1|root,COG0111@2|Bacteria,4NGEB@976|Bacteroidetes,2FMMV@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate	pdxB	-	1.1.1.290	ko:K03473	ko00750,ko01100,map00750,map01100	M00124	R04210	RC00084	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C,DUF3410
TLS3_k127_8045373_0	641524.ADICYQ_1990	1.387e-183	584.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,47MH7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_8045373_1	641524.ADICYQ_1990	5.956e-182	580.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,47MH7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_8045373_3	880073.Calab_2830	8.782e-100	335.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
TLS3_k127_8065696_5	509635.N824_13290	3.937e-18	89.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1IPWM@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_8065696_4	1410666.JHXG01000008_gene536	3.482e-30	128.0	COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,2FMT3@200643|Bacteroidia	976|Bacteroidetes	K	transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_8065696_2	620914.JH621260_gene867	7.961e-74	258.0	COG0384@1|root,COG0384@2|Bacteria,4NEWM@976|Bacteroidetes,1HZKX@117743|Flavobacteriia,2YGQD@290174|Aquimarina	976|Bacteroidetes	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
TLS3_k127_8065696_3	1121875.KB907547_gene3131	6.562e-62	216.0	COG0251@1|root,COG0251@2|Bacteria,4NMAM@976|Bacteroidetes,1I1KB@117743|Flavobacteriia	976|Bacteroidetes	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
TLS3_k127_8065696_1	926559.JoomaDRAFT_1640	2.318e-117	389.0	COG3616@1|root,COG3616@2|Bacteria,4NF5K@976|Bacteroidetes,1HZBK@117743|Flavobacteriia	976|Bacteroidetes	E	amino acid aldolase or racemase	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
TLS3_k127_8065696_0	1380600.AUYN01000010_gene854	2.67e-163	520.0	COG2355@1|root,COG2355@2|Bacteria,4NDYZ@976|Bacteroidetes,1HZ07@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M19	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
TLS3_k127_8065696_6	1123035.ARLA01000021_gene864	2.123e-05	55.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	ina	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M6
TLS3_k127_8067106_1	1168034.FH5T_00975	3.496e-148	480.0	COG4225@1|root,COG4225@2|Bacteria,4NDYS@976|Bacteroidetes,2FM61@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl Hydrolase Family 88	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
TLS3_k127_8067106_0	760192.Halhy_1895	2.846e-227	721.0	COG4225@1|root,COG4225@2|Bacteria,4NF1N@976|Bacteroidetes,1IP96@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Heparinase II III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
TLS3_k127_8067106_2	1408473.JHXO01000007_gene972	5.532e-129	421.0	COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,2FNP5@200643|Bacteroidia	976|Bacteroidetes	E	Psort location Cytoplasmic, score	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_8067106_4	1349822.NSB1T_00290	1.921e-88	301.0	COG0524@1|root,COG0524@2|Bacteria,4NG11@976|Bacteroidetes,2FMAX@200643|Bacteroidia,22XEA@171551|Porphyromonadaceae	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
TLS3_k127_8067106_3	1121335.Clst_0827	1.713e-107	353.0	COG1063@1|root,COG1063@2|Bacteria,1TQ60@1239|Firmicutes,248JR@186801|Clostridia	186801|Clostridia	E	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	ko:K19956	ko00051,map00051	-	R03234	RC00089	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_807962_0	1288963.ADIS_3118	3.402e-79	272.0	COG1082@1|root,COG1082@2|Bacteria,4NPBS@976|Bacteroidetes,47Q6G@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_807962_1	290317.Cpha266_2350	5.95e-73	267.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
TLS3_k127_807962_2	999419.HMPREF1077_00419	2.672e-58	221.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,2FM98@200643|Bacteroidia,22WWD@171551|Porphyromonadaceae	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
TLS3_k127_807962_3	28115.HR11_07220	8.542e-48	175.0	COG0845@1|root,COG0845@2|Bacteria,4NDUH@976|Bacteroidetes,2FM9Q@200643|Bacteroidia,22W2T@171551|Porphyromonadaceae	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS3_k127_8084452_2	1211813.CAPH01000006_gene1548	6.545e-58	207.0	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,2FN0H@200643|Bacteroidia,22UF2@171550|Rikenellaceae	976|Bacteroidetes	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
TLS3_k127_8084452_4	385682.AFSL01000002_gene1868	1.731e-49	182.0	COG3762@1|root,COG3762@2|Bacteria,4NQIT@976|Bacteroidetes,2FTHS@200643|Bacteroidia,3XK37@558415|Marinilabiliaceae	976|Bacteroidetes	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
TLS3_k127_8084452_1	1237149.C900_00796	2.28e-69	240.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,47JGT@768503|Cytophagia	976|Bacteroidetes	S	PFAM LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
TLS3_k127_8084452_0	483216.BACEGG_03598	2.214e-103	345.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,2FNMC@200643|Bacteroidia,4AK98@815|Bacteroidaceae	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
TLS3_k127_8084452_3	143224.JQMD01000002_gene37	3.4e-55	197.0	COG0673@1|root,COG0673@2|Bacteria,4NG5T@976|Bacteroidetes,1I12X@117743|Flavobacteriia	976|Bacteroidetes	S	Putative oxidoreductase C terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,Oxidoreduct_C
TLS3_k127_8086176_1	929562.Emtol_2336	2.85e-71	251.0	COG1082@1|root,COG1082@2|Bacteria,4P26V@976|Bacteroidetes,47YK8@768503|Cytophagia	976|Bacteroidetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS3_k127_8086176_0	1121904.ARBP01000011_gene1574	3.02e-76	270.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CHU_C,PKD,fn3
TLS3_k127_8097951_1	1168034.FH5T_08385	9.228e-135	456.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,2FQ6Y@200643|Bacteroidia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
TLS3_k127_8097951_0	927658.AJUM01000043_gene704	9.544e-145	472.0	COG1418@1|root,COG2114@1|root,COG1418@2|Bacteria,COG2114@2|Bacteria,4NFAG@976|Bacteroidetes,2G21A@200643|Bacteroidia,3XIWF@558415|Marinilabiliaceae	976|Bacteroidetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HD
TLS3_k127_8097951_2	886379.AEWI01000024_gene383	3.251e-12	68.0	COG1629@1|root,COG1629@2|Bacteria,4NUZP@976|Bacteroidetes,2FXZC@200643|Bacteroidia,3XK6W@558415|Marinilabiliaceae	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
TLS3_k127_8107846_1	1168034.FH5T_00990	1.812e-213	680.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,4NEM0@976|Bacteroidetes,2FWDE@200643|Bacteroidia	976|Bacteroidetes	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
TLS3_k127_8107846_6	1168034.FH5T_00995	1.086e-113	379.0	COG0613@1|root,COG0613@2|Bacteria,4NGUQ@976|Bacteroidetes,2FR3M@200643|Bacteroidia	976|Bacteroidetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
TLS3_k127_8107846_5	1168034.FH5T_19705	9.465e-126	410.0	COG0667@1|root,COG0667@2|Bacteria,4NF06@976|Bacteroidetes,2G2UC@200643|Bacteroidia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_8107846_10	545695.TREAZ_2314	8.296e-58	208.0	COG0637@1|root,COG0637@2|Bacteria,2J814@203691|Spirochaetes	203691|Spirochaetes	F	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	HAD_2,dCMP_cyt_deam_1
TLS3_k127_8107846_11	760011.Spico_0120	1.16e-41	160.0	COG0235@1|root,COG0235@2|Bacteria,2J6GN@203691|Spirochaetes	203691|Spirochaetes	G	PFAM Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
TLS3_k127_8107846_7	118168.MC7420_6076	2.393e-110	362.0	COG0647@1|root,COG0647@2|Bacteria,1GCWQ@1117|Cyanobacteria,1HEEW@1150|Oscillatoriales	1117|Cyanobacteria	G	Belongs to the HAD-like hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
TLS3_k127_8107846_0	385682.AFSL01000072_gene1345	0.0	1279.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4N@976|Bacteroidetes,2G2S8@200643|Bacteroidia	976|Bacteroidetes	C	K00162 pyruvate dehydrogenase E1 component subunit beta	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
TLS3_k127_8107846_4	742725.HMPREF9450_01256	1.069e-128	422.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,2FRGM@200643|Bacteroidia	976|Bacteroidetes	C	e3 binding domain	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS3_k127_8107846_9	385682.AFSL01000072_gene1343	4.663e-80	273.0	COG2188@1|root,COG2188@2|Bacteria,4NFVY@976|Bacteroidetes,2FXB6@200643|Bacteroidia	976|Bacteroidetes	K	UTRA	-	-	-	ko:K03710,ko:K10711	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
TLS3_k127_8107846_3	234267.Acid_3464	1.371e-178	571.0	COG3669@1|root,COG3669@2|Bacteria,3Y43P@57723|Acidobacteria	2|Bacteria	G	PFAM glycoside hydrolase, family 29	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,TAT_signal
TLS3_k127_8107846_2	1408473.JHXO01000004_gene50	2.293e-203	641.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,2FQNW@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_8107846_13	865861.AZSU01000009_gene600	2.961e-14	74.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,36MMP@31979|Clostridiaceae	186801|Clostridia	K	Cold shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
TLS3_k127_8107846_12	376686.Fjoh_1303	1.722e-31	126.0	COG0724@1|root,COG0724@2|Bacteria,4NV5J@976|Bacteroidetes,1II63@117743|Flavobacteriia,2P0AX@237|Flavobacterium	976|Bacteroidetes	S	RNA-binding protein	ykfA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
TLS3_k127_8107846_8	1123248.KB893359_gene2071	2.709e-109	359.0	COG1432@1|root,COG1432@2|Bacteria,4NGF1@976|Bacteroidetes,1IRKK@117747|Sphingobacteriia	976|Bacteroidetes	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
TLS3_k127_8122184_4	1453500.AT05_10725	5.945e-120	393.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,1HXRF@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
TLS3_k127_8122184_1	1168289.AJKI01000007_gene157	0.0	1176.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,2FNNW@200643|Bacteroidia,3XJJ6@558415|Marinilabiliaceae	976|Bacteroidetes	O	AAA ATPase domain	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
TLS3_k127_8122184_0	1408473.JHXO01000007_gene857	0.0	1214.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,2FMCP@200643|Bacteroidia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
TLS3_k127_8122184_7	1408473.JHXO01000007_gene856	1.555e-66	242.0	COG4783@1|root,COG4783@2|Bacteria,4P1TE@976|Bacteroidetes,2G0E9@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
TLS3_k127_8122184_3	1121481.AUAS01000009_gene3	3.402e-123	408.0	COG0531@1|root,COG0531@2|Bacteria,4NIZB@976|Bacteroidetes,47NQE@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294,ko:K03758	-	-	-	-	ko00000,ko02000	2.A.3.2	-	-	AA_permease_2
TLS3_k127_8122184_5	1408473.JHXO01000008_gene2760	1.179e-104	356.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_8122184_2	886379.AEWI01000007_gene769	1.775e-169	539.0	COG4948@1|root,COG4948@2|Bacteria,4NG8N@976|Bacteroidetes,2FNCM@200643|Bacteroidia,3XJ2I@558415|Marinilabiliaceae	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	ykfB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20,5.1.1.3	ko:K01776,ko:K19802	ko00471,ko01100,map00471,map01100	-	R00260,R10938	RC00302,RC03309	ko00000,ko00001,ko01000,ko01011	-	-	-	MR_MLE_C,MR_MLE_N
TLS3_k127_8122184_6	926556.Echvi_3615	1.517e-82	288.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,47PND@768503|Cytophagia	976|Bacteroidetes	M	Cell wall-associated hydrolase (invasion-associated protein)	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
TLS3_k127_8200566_1	869213.JCM21142_52279	1.378e-190	606.0	COG1449@1|root,COG1449@2|Bacteria,4NFXW@976|Bacteroidetes,47P2J@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 57 family	amyA	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
TLS3_k127_8200566_0	742817.HMPREF9449_00278	0.0	1537.0	COG0058@1|root,COG0297@1|root,COG0058@2|Bacteria,COG0297@2|Bacteria,4NGR1@976|Bacteroidetes,2FNN5@200643|Bacteroidia,22WPC@171551|Porphyromonadaceae	976|Bacteroidetes	G	alpha-glucan phosphorylase	glgP	-	2.4.1.1,2.4.1.11,2.4.1.8	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R00292,R01555,R02111	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GH65,GT3,GT35	-	DUF3417,Glycogen_syn,Phosphorylase
TLS3_k127_8220157_0	1121859.KB890739_gene2480	1.573e-148	474.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,47MQI@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_8220157_1	1408473.JHXO01000001_gene2422	1.311e-58	212.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,2FMV3@200643|Bacteroidia	976|Bacteroidetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
TLS3_k127_8220157_2	1453498.LG45_12955	6.321e-07	57.0	2E4I5@1|root,32ZD8@2|Bacteria,4NV9B@976|Bacteroidetes,1I50D@117743|Flavobacteriia,2NUJJ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8225142_5	694427.Palpr_1933	2.33e-15	77.0	COG0526@1|root,COG0526@2|Bacteria,4NNMK@976|Bacteroidetes,2FQ45@200643|Bacteroidia,22XXA@171551|Porphyromonadaceae	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
TLS3_k127_8225142_1	1408473.JHXO01000001_gene2404	2.615e-82	294.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,2FQ2M@200643|Bacteroidia	976|Bacteroidetes	S	Peptidase, M28 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
TLS3_k127_8225142_0	357808.RoseRS_1608	1.106e-93	316.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
TLS3_k127_8225142_6	1235803.C825_02965	1.777e-08	63.0	2924H@1|root,2ZPPH@2|Bacteria,4NNST@976|Bacteroidetes,2FR7C@200643|Bacteroidia,22YFV@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4251)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4251
TLS3_k127_8225142_4	1144313.PMI10_04191	1.605e-30	124.0	COG4068@1|root,COG4068@2|Bacteria,4NQ3Z@976|Bacteroidetes,1I2T2@117743|Flavobacteriia,2NW8Q@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
TLS3_k127_8225142_3	926562.Oweho_0234	3.1e-36	140.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I2UG@117743|Flavobacteriia,2PB27@246874|Cryomorphaceae	976|Bacteroidetes	L	TIGRFAM single stranded DNA-binding protein (ssb)	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
TLS3_k127_8225142_2	583355.Caka_0059	2.712e-58	213.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	3.2.1.83	ko:K20846	-	-	-	-	ko00000,ko01000	-	GH16	-	Big_4,Glyco_hydro_16,RicinB_lectin_2
TLS3_k127_8225142_7	1033732.CAHI01000035_gene2801	2.731e-05	51.0	COG0457@1|root,COG0457@2|Bacteria,4PJP5@976|Bacteroidetes,2G24Z@200643|Bacteroidia,22UV8@171550|Rikenellaceae	976|Bacteroidetes	S	Domain of unknown function (DUF5107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5107,TPR_16
TLS3_k127_8230305_1	742817.HMPREF9449_01692	2.689e-74	252.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,2FMWN@200643|Bacteroidia,22XMM@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
TLS3_k127_8230305_3	1168034.FH5T_10835	2.113e-58	208.0	COG0634@1|root,COG0634@2|Bacteria,4NNIB@976|Bacteroidetes,2FN5J@200643|Bacteroidia	976|Bacteroidetes	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
TLS3_k127_8230305_2	714943.Mucpa_4494	1.431e-59	211.0	COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,1IRJW@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
TLS3_k127_8230305_0	385682.AFSL01000008_gene2554	8.633e-163	517.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,2FM6Z@200643|Bacteroidia,3XJ4T@558415|Marinilabiliaceae	976|Bacteroidetes	S	GTP1/OBG	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
TLS3_k127_8230305_5	1168289.AJKI01000003_gene2793	1.235e-39	154.0	COG0671@1|root,COG0671@2|Bacteria,4NNVQ@976|Bacteroidetes,2FRKS@200643|Bacteroidia,3XK0T@558415|Marinilabiliaceae	976|Bacteroidetes	I	Acid phosphatase homologues	ybjG	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
TLS3_k127_8230305_4	1408473.JHXO01000001_gene2083	4.673e-49	183.0	COG0095@1|root,COG0095@2|Bacteria,4NE5F@976|Bacteroidetes,2FMDJ@200643|Bacteroidia	976|Bacteroidetes	H	Lipoate-protein ligase	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
TLS3_k127_8238766_4	1304885.AUEY01000101_gene2140	1.417e-41	154.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2MIZ3@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
TLS3_k127_8238766_0	385682.AFSL01000003_gene1935	1.64e-242	759.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,2FNYK@200643|Bacteroidia,3XJW9@558415|Marinilabiliaceae	976|Bacteroidetes	C	Phosphoenolpyruvate carboxykinase	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
TLS3_k127_8238766_3	929556.Solca_2454	1.213e-57	207.0	COG0344@1|root,COG0344@2|Bacteria,4NMU3@976|Bacteroidetes,1IPFE@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
TLS3_k127_8238766_1	435591.BDI_3032	9.124e-81	273.0	COG1592@1|root,COG1592@2|Bacteria,4NH0J@976|Bacteroidetes,2FNC9@200643|Bacteroidia,22WSM@171551|Porphyromonadaceae	976|Bacteroidetes	C	Rubrerythrin	rbr	GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
TLS3_k127_8238766_2	880074.BARVI_03640	4.601e-64	224.0	COG0778@1|root,COG0778@2|Bacteria,4NPZV@976|Bacteroidetes,2FNIP@200643|Bacteroidia,22XS9@171551|Porphyromonadaceae	976|Bacteroidetes	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
TLS3_k127_8257557_1	742725.HMPREF9450_00225	3.273e-133	437.0	COG3250@1|root,COG3250@2|Bacteria,4NGZH@976|Bacteroidetes,2FN7Y@200643|Bacteroidia	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
TLS3_k127_8257557_0	203275.BFO_0490	7.825e-205	647.0	COG5434@1|root,COG5434@2|Bacteria,4NFSC@976|Bacteroidetes,2FNQN@200643|Bacteroidia,22Y8F@171551|Porphyromonadaceae	976|Bacteroidetes	G	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
TLS3_k127_8274149_6	886379.AEWI01000029_gene214	1.121e-55	201.0	COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,3XJ00@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal protein S1-like RNA-binding domain	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
TLS3_k127_8274149_1	385682.AFSL01000003_gene1921	6.163e-194	613.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,2FMZ9@200643|Bacteroidia,3XJPW@558415|Marinilabiliaceae	976|Bacteroidetes	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TLS3_k127_8274149_2	1408473.JHXO01000011_gene3206	3.288e-139	447.0	COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,2FNUA@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
TLS3_k127_8274149_5	694427.Palpr_1217	2.273e-66	230.0	COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,2FMBP@200643|Bacteroidia,22XD8@171551|Porphyromonadaceae	976|Bacteroidetes	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
TLS3_k127_8274149_3	1122931.AUAE01000018_gene3896	6.277e-85	289.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,2FN7H@200643|Bacteroidia,22WWK@171551|Porphyromonadaceae	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
TLS3_k127_8274149_0	385682.AFSL01000003_gene1926	1.28e-220	698.0	COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,3XJNB@558415|Marinilabiliaceae	976|Bacteroidetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	pgcA	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TLS3_k127_8274149_4	941824.TCEL_00879	2.287e-76	257.0	COG0432@1|root,COG0432@2|Bacteria,1V201@1239|Firmicutes,24FTY@186801|Clostridia,36IW8@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
TLS3_k127_8274149_7	1236494.BAJN01000007_gene1160	5.348e-08	64.0	COG3577@1|root,COG3577@2|Bacteria,4NMGA@976|Bacteroidetes,2FP7G@200643|Bacteroidia	976|Bacteroidetes	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
TLS3_k127_8280637_0	243231.GSU0518	1.389e-147	485.0	COG4147@1|root,COG4147@2|Bacteria,1QXN2@1224|Proteobacteria,43C45@68525|delta/epsilon subdivisions,2WK6N@28221|Deltaproteobacteria,43TZ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Sodium:solute symporter family	aplD	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
TLS3_k127_8280637_1	1191523.MROS_0242	1.17e-113	379.0	292UM@1|root,2ZQC9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8280637_2	1304885.AUEY01000007_gene1357	2.948e-107	377.0	COG2202@1|root,COG2905@1|root,COG4564@1|root,COG2202@2|Bacteria,COG2905@2|Bacteria,COG4564@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2WJF5@28221|Deltaproteobacteria,2MIA9@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Putative nucleotidyltransferase substrate binding domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,PAS_8,cNMP_binding,sCache_2
TLS3_k127_8280637_5	371042.NG99_08040	7.994e-39	154.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
TLS3_k127_8280637_4	1121890.AUDO01000003_gene1909	9.613e-40	151.0	COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes,1I2XY@117743|Flavobacteriia,2NWVD@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
TLS3_k127_8280637_3	667015.Bacsa_1758	1.987e-41	162.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,2FM72@200643|Bacteroidia,4AKT0@815|Bacteroidaceae	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_8288408_1	1168289.AJKI01000008_gene753	6.195e-83	288.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,2FPGX@200643|Bacteroidia,3XJHH@558415|Marinilabiliaceae	976|Bacteroidetes	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
TLS3_k127_8288408_0	742817.HMPREF9449_01589	5.042e-106	362.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,2FM9F@200643|Bacteroidia,22W8Y@171551|Porphyromonadaceae	976|Bacteroidetes	M	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8300502_2	927658.AJUM01000042_gene1611	7.024e-72	251.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,2FM1J@200643|Bacteroidia,3XJIH@558415|Marinilabiliaceae	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
TLS3_k127_8300502_4	468059.AUHA01000002_gene15	7.518e-27	118.0	COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,1ISN7@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA uptake protein and related DNA-binding	comEA	-	-	-	-	-	-	-	-	-	-	-	HHH_3
TLS3_k127_8300502_5	385682.AFSL01000100_gene33	4.144e-24	102.0	COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,2FUNX@200643|Bacteroidia,3XKEV@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
TLS3_k127_8300502_1	929556.Solca_0409	1.829e-87	298.0	COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,1IP2Y@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
TLS3_k127_8300502_3	1408433.JHXV01000007_gene2897	2.587e-29	119.0	COG1544@1|root,COG1544@2|Bacteria,4NUME@976|Bacteroidetes,1IMXN@117743|Flavobacteriia,2PB40@246874|Cryomorphaceae	976|Bacteroidetes	J	PFAM Sigma 54 modulation protein S30EA ribosomal protein	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
TLS3_k127_8300502_0	709991.Odosp_1971	3.221e-156	495.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
TLS3_k127_8300574_0	471854.Dfer_5259	8.47e-171	554.0	COG1395@1|root,COG1395@2|Bacteria,4PMSD@976|Bacteroidetes,47Y95@768503|Cytophagia	976|Bacteroidetes	K	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_8300574_2	1121921.KB898709_gene319	4.116e-05	48.0	COG4948@1|root,COG4948@2|Bacteria,1QVFR@1224|Proteobacteria,1T2Y2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl-hydrolase 97 C-terminal, oligomerisation	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
TLS3_k127_8316622_0	880070.Cycma_4413	0.0	1237.0	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,4P0T2@976|Bacteroidetes,47U4A@768503|Cytophagia	976|Bacteroidetes	HP	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_8316622_2	880070.Cycma_4414	5.047e-164	529.0	COG0702@1|root,COG0702@2|Bacteria,4P04A@976|Bacteroidetes,47U2J@768503|Cytophagia	976|Bacteroidetes	GM	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_8316622_5	880070.Cycma_4415	2.687e-48	178.0	2F8H2@1|root,340VW@2|Bacteria,4P4P8@976|Bacteroidetes,47VGN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8316622_1	1168289.AJKI01000015_gene2180	4.308e-245	764.0	COG3303@1|root,COG3303@2|Bacteria,4NG0P@976|Bacteroidetes,2FP37@200643|Bacteroidia,3XKSC@558415|Marinilabiliaceae	976|Bacteroidetes	P	Cytochrome c552	nrfA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0016661,GO:0016662,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044237,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0098809,GO:1901363	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
TLS3_k127_8316622_4	869213.JCM21142_136	1.292e-86	289.0	COG3005@1|root,COG3005@2|Bacteria,4NK7R@976|Bacteroidetes,47M7M@768503|Cytophagia	976|Bacteroidetes	C	PFAM NapC NirT cytochrome c family, N-terminal region	nrfH	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
TLS3_k127_8316622_3	1121899.Q764_04315	8.461e-133	425.0	COG1506@1|root,COG1506@2|Bacteria,4NE60@976|Bacteroidetes,1HX05@117743|Flavobacteriia,2NS7N@237|Flavobacterium	976|Bacteroidetes	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
TLS3_k127_8323182_3	1296416.JACB01000067_gene15	1.67e-58	207.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1HWVH@117743|Flavobacteriia,2YH6J@290174|Aquimarina	976|Bacteroidetes	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TLS3_k127_8323182_2	1408473.JHXO01000010_gene3512	4.889e-98	326.0	COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,2FP7M@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS3_k127_8323182_1	1168034.FH5T_04750	1.138e-120	393.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,2FN64@200643|Bacteroidia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
TLS3_k127_8323182_0	869213.JCM21142_102	1.784e-187	594.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,47K6M@768503|Cytophagia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
TLS3_k127_8323182_4	929562.Emtol_1612	1.108e-10	69.0	2E691@1|root,330X3@2|Bacteria,4NVM3@976|Bacteroidetes,47RUJ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8340022_7	1236514.BAKL01000024_gene2324	4.085e-08	55.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,2FMKP@200643|Bacteroidia,4AMNK@815|Bacteroidaceae	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
TLS3_k127_8340022_3	866536.Belba_3053	5.526e-158	515.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47M14@768503|Cytophagia	976|Bacteroidetes	G	Peptidase, M28	PGCP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
TLS3_k127_8340022_1	1120968.AUBX01000002_gene1452	1.269e-236	746.0	COG0644@1|root,COG0644@2|Bacteria,4PKHH@976|Bacteroidetes,47YHF@768503|Cytophagia	976|Bacteroidetes	C	Glucose inhibited division protein A	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
TLS3_k127_8340022_0	1408473.JHXO01000005_gene1681	3.872e-301	939.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,2FMAZ@200643|Bacteroidia	976|Bacteroidetes	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
TLS3_k127_8340022_2	869213.JCM21142_93444	2.293e-160	515.0	COG1092@1|root,COG1092@2|Bacteria,4NG9S@976|Bacteroidetes,47M5H@768503|Cytophagia	976|Bacteroidetes	J	SAM-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
TLS3_k127_8340022_5	1408473.JHXO01000005_gene1653	5.578e-58	207.0	COG0349@1|root,COG0349@2|Bacteria,4NP3B@976|Bacteroidetes,2FN2U@200643|Bacteroidia	976|Bacteroidetes	L	3'-5' exonuclease	rnd	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A_exo1
TLS3_k127_8340022_6	886379.AEWI01000211_gene2510	9.273e-50	184.0	2AIA7@1|root,318R1@2|Bacteria,4NQPK@976|Bacteroidetes,2FPYF@200643|Bacteroidia,3XJE3@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF5063)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5063
TLS3_k127_8340022_4	118005.AWNK01000009_gene252	7.945e-90	301.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	dld	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8
TLS3_k127_8341396_5	1121097.JCM15093_2859	4.788e-15	83.0	2E6TM@1|root,331DG@2|Bacteria,4NYW8@976|Bacteroidetes,2FPEV@200643|Bacteroidia,4APRK@815|Bacteroidaceae	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
TLS3_k127_8341396_3	1408473.JHXO01000007_gene720	4.975e-59	212.0	arCOG14808@1|root,308PC@2|Bacteria,4NR4D@976|Bacteroidetes,2FR8F@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
TLS3_k127_8341396_4	1408473.JHXO01000007_gene719	3.778e-42	165.0	COG3025@1|root,COG3025@2|Bacteria,4NM6K@976|Bacteroidetes,2FNF2@200643|Bacteroidia	976|Bacteroidetes	S	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
TLS3_k127_8341396_2	435591.BDI_2624	1.957e-135	441.0	COG1082@1|root,COG1082@2|Bacteria,4NFQY@976|Bacteroidetes,2FWU9@200643|Bacteroidia,22ZRC@171551|Porphyromonadaceae	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_8341396_1	435591.BDI_2625	1.038e-201	640.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes	976|Bacteroidetes	S	Pfam Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_8341396_0	1453498.LG45_07885	1.555e-236	745.0	COG1506@1|root,COG1506@2|Bacteria,4NE60@976|Bacteroidetes,1HX05@117743|Flavobacteriia,2NS7N@237|Flavobacterium	976|Bacteroidetes	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
TLS3_k127_8341679_3	471854.Dfer_3074	2.344e-39	147.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,47JQT@768503|Cytophagia	976|Bacteroidetes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
TLS3_k127_8341679_0	1408473.JHXO01000011_gene2962	2.019e-177	561.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,2FM2I@200643|Bacteroidia	976|Bacteroidetes	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
TLS3_k127_8341679_1	1408473.JHXO01000011_gene2963	7.869e-63	225.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,2FMWS@200643|Bacteroidia	976|Bacteroidetes	M	shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
TLS3_k127_8341679_2	1408473.JHXO01000011_gene2964	1.627e-44	168.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,2FPJA@200643|Bacteroidia	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8344303_5	1499967.BAYZ01000139_gene153	4.824e-34	130.0	COG1418@1|root,COG1418@2|Bacteria,2NPXI@2323|unclassified Bacteria	2|Bacteria	S	mRNA catabolic process	-	-	-	ko:K06950,ko:K09163	-	-	-	-	ko00000	-	-	-	HD
TLS3_k127_8344303_0	929556.Solca_3525	7.02e-259	812.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1IPQT@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
TLS3_k127_8344303_2	869213.JCM21142_41820	1.95e-182	579.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,47JQ0@768503|Cytophagia	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
TLS3_k127_8344303_7	1356852.N008_09720	2.402e-07	60.0	2DYGZ@1|root,32V5E@2|Bacteria,4NSGC@976|Bacteroidetes,47SKW@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3575)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3575
TLS3_k127_8344303_3	1408473.JHXO01000011_gene3054	1.088e-65	227.0	COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,2FN4T@200643|Bacteroidia	976|Bacteroidetes	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
TLS3_k127_8344303_1	1211813.CAPH01000005_gene1688	3.606e-249	790.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,2FMEE@200643|Bacteroidia,22U0C@171550|Rikenellaceae	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
TLS3_k127_8344303_6	1185876.BN8_01136	4.216e-09	69.0	COG3291@1|root,COG3291@2|Bacteria,4NTHY@976|Bacteroidetes,47RAV@768503|Cytophagia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_8344303_4	1408813.AYMG01000008_gene3831	5.088e-45	168.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1IQAH@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_8345814_1	484018.BACPLE_00376	9.216e-55	200.0	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,2FMM7@200643|Bacteroidia,4AKY1@815|Bacteroidaceae	976|Bacteroidetes	H	biotin acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
TLS3_k127_8345814_3	385682.AFSL01000024_gene2054	2.953e-17	87.0	COG3427@1|root,COG3427@2|Bacteria,4NUYJ@976|Bacteroidetes,2FS4N@200643|Bacteroidia,3XK9I@558415|Marinilabiliaceae	976|Bacteroidetes	S	Polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_8345814_0	742817.HMPREF9449_01625	8.395e-84	283.0	COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,2FMTB@200643|Bacteroidia,22XEK@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10,4.1.1.23	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
TLS3_k127_8345814_2	445961.IW15_18470	6.697e-33	134.0	COG1051@1|root,COG1051@2|Bacteria,4NS9I@976|Bacteroidetes,1HZFF@117743|Flavobacteriia,3ZNKT@59732|Chryseobacterium	976|Bacteroidetes	F	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_8349837_0	1382359.JIAL01000001_gene1322	4.415e-139	451.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Redoxin,Thioredoxin_8,UnbV_ASPIC,VCBS
TLS3_k127_8349837_1	504472.Slin_4694	5.353e-129	419.0	COG1052@1|root,COG1052@2|Bacteria,4NIHV@976|Bacteroidetes,47NBS@768503|Cytophagia	976|Bacteroidetes	CH	D-isomer specific 2-hydroxyacid dehydrogenase	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TLS3_k127_8349837_4	1216967.L100_09224	6.578e-36	140.0	COG2402@1|root,COG2402@2|Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN,PIN_3
TLS3_k127_8349837_5	1216967.L100_09229	7.112e-22	97.0	2AMWJ@1|root,31CTC@2|Bacteria,4PBSE@976|Bacteroidetes,1IIHE@117743|Flavobacteriia,34SCB@308865|Elizabethkingia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8349837_2	1408473.JHXO01000005_gene1559	2.23e-124	411.0	COG0667@1|root,COG0667@2|Bacteria,4NGRK@976|Bacteroidetes	976|Bacteroidetes	C	Pfam Aldo keto reductase family	-	-	1.1.1.122	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	M00114	R07675,R08926	RC00066,RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
TLS3_k127_8349837_3	268407.PWYN_04830	2.639e-50	192.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,4HABC@91061|Bacilli,274FT@186822|Paenibacillaceae	91061|Bacilli	E	Alcohol dehydrogenase GroES-like domain	tdh	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_8350046_6	1408473.JHXO01000001_gene2058	7.177e-37	144.0	COG0730@1|root,COG0730@2|Bacteria,4NH6M@976|Bacteroidetes,2FSUD@200643|Bacteroidia	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_8350046_2	945713.IALB_2772	3.951e-156	505.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	pepQ	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
TLS3_k127_8350046_4	1123248.KB893381_gene952	9.949e-105	353.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1INV5@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_8350046_1	1499967.BAYZ01000032_gene1138	2.393e-212	667.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
TLS3_k127_8350046_3	1499967.BAYZ01000032_gene1134	1.715e-145	470.0	COG0673@1|root,COG0673@2|Bacteria,2NQM5@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_8350046_0	1122605.KB893637_gene3221	2.874e-250	777.0	COG0160@1|root,COG0160@2|Bacteria,4NIHH@976|Bacteroidetes,1IWIQ@117747|Sphingobacteriia	976|Bacteroidetes	E	COGs COG0160 4-aminobutyrate aminotransferase and related aminotransferase	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS3_k127_8350046_7	339860.Msp_0091	4.573e-30	130.0	COG1830@1|root,arCOG04044@2157|Archaea,2XTBQ@28890|Euryarchaeota,23NT7@183925|Methanobacteria	183925|Methanobacteria	E	Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids	aroA'	-	2.2.1.10,4.1.2.13	ko:K16306	ko00010,ko00030,ko00051,ko00400,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00400,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001	R01068,R01070,R02568,R08568	RC00438,RC00439,RC00721,RC02301	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
TLS3_k127_8350046_5	33035.JPJF01000084_gene5098	4.3e-90	310.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,25M5K@186801|Clostridia,3Y1AP@572511|Blautia	186801|Clostridia	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
TLS3_k127_8408560_0	1168034.FH5T_07580	7.113e-173	549.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FMRV@200643|Bacteroidia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_8408560_1	1168034.FH5T_07585	7.359e-120	399.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,2FMRD@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
TLS3_k127_8408560_2	1408473.JHXO01000001_gene2520	1.116e-73	256.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,2FP1Q@200643|Bacteroidia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
TLS3_k127_8412952_9	404380.Gbem_1303	2.756e-81	280.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,42Z4V@68525|delta/epsilon subdivisions,2WU31@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
TLS3_k127_8412952_11	714943.Mucpa_6923	4.61e-73	255.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,1IPBH@117747|Sphingobacteriia	976|Bacteroidetes	H	UBA THIF-type NAD FAD binding protein	thiF	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
TLS3_k127_8412952_4	1158294.JOMI01000002_gene3091	1.927e-105	347.0	COG3340@1|root,COG3340@2|Bacteria,4NEXW@976|Bacteroidetes,2FQTC@200643|Bacteroidia	976|Bacteroidetes	E	Belongs to the peptidase S51 family	pepE	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
TLS3_k127_8412952_12	269798.CHU_0208	2.425e-63	246.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,47KTA@768503|Cytophagia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
TLS3_k127_8412952_5	1122931.AUAE01000023_gene1530	1.726e-103	348.0	COG4191@1|root,COG4191@2|Bacteria,4NEMP@976|Bacteroidetes,2FPJR@200643|Bacteroidia,22VVD@171551|Porphyromonadaceae	976|Bacteroidetes	T	Histidine kinase	vicK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
TLS3_k127_8412952_2	742767.HMPREF9456_02065	1.974e-169	542.0	COG0826@1|root,COG0826@2|Bacteria,4NERN@976|Bacteroidetes,2FN1E@200643|Bacteroidia,22VVZ@171551|Porphyromonadaceae	976|Bacteroidetes	O	collagenase	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
TLS3_k127_8412952_7	1185876.BN8_05484	8.004e-99	333.0	COG2603@1|root,COG2603@2|Bacteria,4NH7W@976|Bacteroidetes,47KFW@768503|Cytophagia	976|Bacteroidetes	S	Rhodanese Homology Domain	-	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
TLS3_k127_8412952_6	869213.JCM21142_1685	3.563e-100	360.0	COG5002@1|root,COG5002@2|Bacteria,4PKV1@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_8,Response_reg
TLS3_k127_8412952_3	927658.AJUM01000037_gene1842	2.213e-107	355.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,2FNY9@200643|Bacteroidia,3XIJX@558415|Marinilabiliaceae	976|Bacteroidetes	S	RsgA N-terminal domain	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
TLS3_k127_8412952_0	204669.Acid345_1623	2.943e-194	612.0	COG0205@1|root,COG0205@2|Bacteria,3Y4A9@57723|Acidobacteria,2JKQ8@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphofructokinase	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
TLS3_k127_8412952_1	929713.NIASO_05310	1.719e-183	582.0	COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,1IUVG@117747|Sphingobacteriia	976|Bacteroidetes	G	Phosphofructokinase	pfp	-	2.7.1.11,2.7.1.90	ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
TLS3_k127_8412952_10	1202532.FF52_09302	1.892e-77	269.0	COG1090@1|root,COG1090@2|Bacteria,4NINM@976|Bacteroidetes,1HXRB@117743|Flavobacteriia,2NSBA@237|Flavobacterium	976|Bacteroidetes	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
TLS3_k127_8412952_8	1047013.AQSP01000134_gene1334	1.647e-95	317.0	COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
TLS3_k127_8424002_2	1408473.JHXO01000006_gene1089	4.155e-59	213.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,2FMM9@200643|Bacteroidia	976|Bacteroidetes	O	Psort location Cytoplasmic, score 8.96	gldB	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8424002_0	1223410.KN050846_gene379	0.0	1104.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia	976|Bacteroidetes	P	heavy metal translocating P-type ATPase	silP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
TLS3_k127_8424002_3	1168289.AJKI01000014_gene2066	5.864e-29	116.0	COG2768@1|root,COG2768@2|Bacteria,4NUN8@976|Bacteroidetes,2FUIC@200643|Bacteroidia,3XKDM@558415|Marinilabiliaceae	976|Bacteroidetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
TLS3_k127_8424002_1	1408433.JHXV01000010_gene496	5.22e-113	385.0	COG4775@1|root,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1I8E9@117743|Flavobacteriia,2PBCC@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM WD40-like beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_8430205_1	313596.RB2501_12302	1.151e-113	383.0	COG2091@1|root,COG2091@2|Bacteria,4NGXG@976|Bacteroidetes,1HZ27@117743|Flavobacteriia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_8430205_0	1408473.JHXO01000008_gene2747	1.136e-188	601.0	COG1032@1|root,COG1032@2|Bacteria,4NFPW@976|Bacteroidetes,2FY68@200643|Bacteroidia	976|Bacteroidetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
TLS3_k127_8430205_2	1210884.HG799471_gene14621	3.101e-108	365.0	COG2041@1|root,COG2041@2|Bacteria	2|Bacteria	V	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
TLS3_k127_8430205_6	435591.BDI_0771	1.941e-22	102.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	ABM,MFS_3
TLS3_k127_8430205_4	886379.AEWI01000059_gene2758	2.313e-37	142.0	COG2706@1|root,COG2706@2|Bacteria,4NJU4@976|Bacteroidetes	976|Bacteroidetes	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8430205_3	1408473.JHXO01000003_gene2545	8.208e-79	271.0	COG0491@1|root,COG0491@2|Bacteria,4NPPW@976|Bacteroidetes,2FS1P@200643|Bacteroidia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	ccrA	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
TLS3_k127_8430205_5	558152.IQ37_03915	4.867e-24	105.0	2E49F@1|root,32Z57@2|Bacteria,4PKEJ@976|Bacteroidetes,1IJCW@117743|Flavobacteriia,3ZUR5@59732|Chryseobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4180)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4180
TLS3_k127_8430205_7	1517682.HW49_09705	7.736e-19	92.0	2F1S9@1|root,33USE@2|Bacteria,4P2N2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8445405_3	595460.RRSWK_04693	1.237e-12	73.0	COG0438@1|root,COG0438@2|Bacteria,2IXZX@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_8445405_2	1168034.FH5T_01515	1.265e-57	207.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,2FKZC@200643|Bacteroidia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
TLS3_k127_8445405_0	1168034.FH5T_01510	4.431e-157	535.0	COG0577@1|root,COG0577@2|Bacteria,4NZYZ@976|Bacteroidetes,2FWFC@200643|Bacteroidia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
TLS3_k127_8445405_1	1210884.HG799469_gene14163	4.654e-124	412.0	COG0666@1|root,COG1520@1|root,COG0666@2|Bacteria,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
TLS3_k127_8445405_4	385682.AFSL01000072_gene1339	3.855e-09	59.0	COG1070@1|root,COG1070@2|Bacteria,4NE3S@976|Bacteroidetes	976|Bacteroidetes	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_N
TLS3_k127_8458082_4	657309.BXY_19340	2.193e-66	233.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,2FP14@200643|Bacteroidia,4AN3K@815|Bacteroidaceae	976|Bacteroidetes	S	ComF family	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
TLS3_k127_8458082_2	1158294.JOMI01000007_gene311	9.067e-74	253.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,2FNM6@200643|Bacteroidia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
TLS3_k127_8458082_3	1123057.P872_13760	1.611e-68	249.0	COG0793@1|root,COG0793@2|Bacteria,4NN5N@976|Bacteroidetes,47XP7@768503|Cytophagia	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
TLS3_k127_8458082_1	1168034.FH5T_10345	1.306e-83	286.0	COG0697@1|root,COG0697@2|Bacteria,4P2CN@976|Bacteroidetes,2FQRW@200643|Bacteroidia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_8458082_0	927658.AJUM01000037_gene2227	5.297e-188	596.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,2FN99@200643|Bacteroidia,3XJ7B@558415|Marinilabiliaceae	976|Bacteroidetes	J	Seryl-tRNA synthetase N-terminal domain	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
TLS3_k127_8458082_5	1434325.AZQN01000002_gene1293	1.459e-38	145.0	COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,47R69@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
TLS3_k127_8458082_6	1249975.JQLP01000001_gene3045	3.592e-34	136.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,1HYAI@117743|Flavobacteriia,2P6US@244698|Gillisia	976|Bacteroidetes	J	Ribosomal prokaryotic L21 protein	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
TLS3_k127_8459456_0	1408473.JHXO01000006_gene1118	7.72e-212	668.0	COG1070@1|root,COG1070@2|Bacteria,4NFBZ@976|Bacteroidetes,2FPIS@200643|Bacteroidia	976|Bacteroidetes	G	Carbohydrate kinase, FGGY family protein	xylB_2	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
TLS3_k127_8459456_1	1380600.AUYN01000009_gene1869	1.221e-187	593.0	COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,1HXW8@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the interconversion of D-xylose to D-xylulose	xylA	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	-
TLS3_k127_8460691_0	1185876.BN8_02102	7.425e-201	643.0	COG0296@1|root,COG0296@2|Bacteria,4PKT8@976|Bacteroidetes,47M5D@768503|Cytophagia	976|Bacteroidetes	G	SMART alpha amylase catalytic sub domain	-	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
TLS3_k127_8460691_1	886379.AEWI01000042_gene3359	2.54e-109	366.0	COG1640@1|root,COG3280@1|root,COG1640@2|Bacteria,COG3280@2|Bacteria,4NF7Z@976|Bacteroidetes,2FMBZ@200643|Bacteroidia,3XJCM@558415|Marinilabiliaceae	976|Bacteroidetes	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Alpha-amylase,Glyco_hydro_77
TLS3_k127_8465163_4	869213.JCM21142_93448	8.581e-41	151.0	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,47R0I@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
TLS3_k127_8465163_1	1168289.AJKI01000031_gene1088	4.816e-113	383.0	COG1934@1|root,COG1934@2|Bacteria,4PKT4@976|Bacteroidetes,2G3HG@200643|Bacteroidia,3XJX6@558415|Marinilabiliaceae	976|Bacteroidetes	S	OstA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OstA_2
TLS3_k127_8465163_2	886379.AEWI01000211_gene2506	2.543e-95	329.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,2FMDU@200643|Bacteroidia,3XIV9@558415|Marinilabiliaceae	976|Bacteroidetes	O	PPIC-type PPIASE domain	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
TLS3_k127_8465163_3	1168034.FH5T_00400	5.863e-59	214.0	COG0760@1|root,COG0760@2|Bacteria,4NG2P@976|Bacteroidetes,2FMWD@200643|Bacteroidia	976|Bacteroidetes	O	COG NOG23400 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
TLS3_k127_8465163_0	1124780.ANNU01000005_gene2434	1.506e-118	403.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,47K78@768503|Cytophagia	976|Bacteroidetes	O	peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
TLS3_k127_8475830_1	1267535.KB906767_gene3867	5.881e-85	287.0	COG4658@1|root,COG4658@2|Bacteria	2|Bacteria	C	electron transport chain	-	-	1.6.5.8	ko:K00347,ko:K03614	-	-	-	-	ko00000,ko01000	-	-	-	Complex1_51K,NQR2_RnfD_RnfE,RnfC_N
TLS3_k127_8475830_0	1267535.KB906767_gene3866	8.895e-93	312.0	COG4658@1|root,COG4658@2|Bacteria	2|Bacteria	C	electron transport chain	-	-	1.6.5.8	ko:K00347,ko:K03614,ko:K21163	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Complex1_51K,NQR2_RnfD_RnfE,RnfC_N,UnbV_ASPIC,VCBS
TLS3_k127_8475830_3	926556.Echvi_3209	1.248e-38	153.0	COG4244@1|root,COG4244@2|Bacteria,4NKH6@976|Bacteroidetes,47S7T@768503|Cytophagia	976|Bacteroidetes	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8475830_2	1168289.AJKI01000044_gene15	2.035e-46	174.0	COG0791@1|root,COG0791@2|Bacteria,4NQSZ@976|Bacteroidetes,2FS8Y@200643|Bacteroidia,3XKT6@558415|Marinilabiliaceae	976|Bacteroidetes	M	NlpC/P60 family	mepS	-	3.4.17.13	ko:K13694	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
TLS3_k127_8478190_3	927658.AJUM01000037_gene1915	5.786e-170	549.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,2FP0Y@200643|Bacteroidia,3XJM9@558415|Marinilabiliaceae	976|Bacteroidetes	M	tail specific protease	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
TLS3_k127_8478190_7	742725.HMPREF9450_00946	1.538e-53	198.0	COG2267@1|root,COG2267@2|Bacteria,4NHA9@976|Bacteroidetes,2FTSQ@200643|Bacteroidia,22USS@171550|Rikenellaceae	976|Bacteroidetes	I	Ndr family	yfbB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_8478190_8	324925.Ppha_2853	3.486e-53	194.0	2CAZH@1|root,2Z7RU@2|Bacteria,1FF0A@1090|Chlorobi	1090|Chlorobi	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
TLS3_k127_8478190_1	153721.MYP_1448	4.639e-294	914.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,47JE5@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
TLS3_k127_8478190_5	761193.Runsl_4725	1.638e-107	353.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,47KHR@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
TLS3_k127_8478190_4	1048983.EL17_10255	3.182e-167	537.0	COG2234@1|root,COG2234@2|Bacteria,4NENF@976|Bacteroidetes,47JMS@768503|Cytophagia	976|Bacteroidetes	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
TLS3_k127_8478190_2	945713.IALB_2772	7.178e-172	550.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	pepQ	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
TLS3_k127_8478190_0	869213.JCM21142_104169	0.0	1148.0	COG3256@1|root,COG3256@2|Bacteria,4NG9H@976|Bacteroidetes,47K63@768503|Cytophagia	976|Bacteroidetes	P	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
TLS3_k127_8478190_6	1279009.ADICEAN_02480	9.59e-69	240.0	COG2846@1|root,COG4309@1|root,COG2846@2|Bacteria,COG4309@2|Bacteria,4NE9M@976|Bacteroidetes,47P55@768503|Cytophagia	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	DUF2249,Hemerythrin,ScdA_N
TLS3_k127_8481991_2	1168034.FH5T_20325	1.581e-48	175.0	COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,2FSHU@200643|Bacteroidia	976|Bacteroidetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
TLS3_k127_8481991_0	869213.JCM21142_3934	2.27e-152	516.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,47KBD@768503|Cytophagia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
TLS3_k127_8481991_6	867845.KI911784_gene2290	1.545e-11	71.0	COG1266@1|root,COG1266@2|Bacteria,2G7NB@200795|Chloroflexi,377D7@32061|Chloroflexia	32061|Chloroflexia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
TLS3_k127_8481991_3	694427.Palpr_2538	1.896e-43	162.0	COG3677@1|root,COG3677@2|Bacteria,4NHKN@976|Bacteroidetes,2FS7V@200643|Bacteroidia	976|Bacteroidetes	L	SPTR Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
TLS3_k127_8481991_5	997884.HMPREF1068_02851	6.031e-13	71.0	COG0607@1|root,COG0607@2|Bacteria,4NXGV@976|Bacteroidetes,2FUKK@200643|Bacteroidia,4AS9C@815|Bacteroidaceae	976|Bacteroidetes	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8481991_1	1307761.L21SP2_2452	3.789e-75	261.0	COG0500@1|root,COG2226@2|Bacteria,2J6Y1@203691|Spirochaetes	203691|Spirochaetes	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
TLS3_k127_8481991_4	357276.EL88_01555	1.461e-42	161.0	COG3118@1|root,COG3118@2|Bacteria,4NQNX@976|Bacteroidetes,2FSPP@200643|Bacteroidia,4ANK1@815|Bacteroidaceae	976|Bacteroidetes	O	Psort location Cytoplasmic, score 9.26	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
TLS3_k127_8481991_7	580327.Tthe_0353	1.689e-06	53.0	COG0641@1|root,COG0641@2|Bacteria,1UZWZ@1239|Firmicutes,25CAG@186801|Clostridia,42GZ9@68295|Thermoanaerobacterales	186801|Clostridia	C	Radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
TLS3_k127_848701_1	1168034.FH5T_17540	1.308e-70	248.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,2FNAY@200643|Bacteroidia	976|Bacteroidetes	S	outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
TLS3_k127_848701_2	886379.AEWI01000024_gene339	4.396e-43	159.0	2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,2FTC9@200643|Bacteroidia,3XK94@558415|Marinilabiliaceae	976|Bacteroidetes	S	RNA polymerase Rpb6	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
TLS3_k127_848701_0	1121129.KB903367_gene2893	4.871e-147	476.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,2FNDG@200643|Bacteroidia,22X4T@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
TLS3_k127_848701_3	1168034.FH5T_17555	9.149e-36	139.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,2FP92@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
TLS3_k127_8491362_3	868595.Desca_0351	1.652e-69	244.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,261IK@186807|Peptococcaceae	186801|Clostridia	KO	Hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
TLS3_k127_8491362_6	891968.Anamo_1414	6.69e-15	78.0	COG0375@1|root,COG0375@2|Bacteria,3TBGH@508458|Synergistetes	508458|Synergistetes	C	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
TLS3_k127_8491362_2	32057.KB217478_gene3886	1.386e-101	341.0	COG0309@1|root,COG0309@2|Bacteria,1G1Z7@1117|Cyanobacteria,1HKMD@1161|Nostocales	1117|Cyanobacteria	O	TIGRFAM hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
TLS3_k127_8491362_1	243164.DET1434	1.621e-113	376.0	COG0409@1|root,COG0409@2|Bacteria,2G5MS@200795|Chloroflexi,34CKT@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Hydrogenase formation hypA family	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
TLS3_k127_8491362_5	247490.KSU1_A0069	3.08e-15	79.0	COG0298@1|root,COG0298@2|Bacteria,2J17F@203682|Planctomycetes	203682|Planctomycetes	O	HupF/HypC family	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
TLS3_k127_8491362_0	1122931.AUAE01000030_gene866	2.753e-227	726.0	COG0068@1|root,COG0068@2|Bacteria,4NIZ1@976|Bacteroidetes,2FRRN@200643|Bacteroidia,22X9I@171551|Porphyromonadaceae	976|Bacteroidetes	O	Acylphosphatase	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Peptidase_M22,Sua5_yciO_yrdC,zf-HYPF
TLS3_k127_8491362_4	1313304.CALK_1494	4.355e-44	169.0	COG2344@1|root,COG2344@2|Bacteria	2|Bacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
TLS3_k127_850329_0	1168034.FH5T_07585	7.856e-67	243.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,2FMRD@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
TLS3_k127_850329_1	234267.Acid_4464	1.13e-62	232.0	COG0296@1|root,COG2382@1|root,COG0296@2|Bacteria,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	glgE	-	2.4.1.18,2.4.99.16	ko:K00700,ko:K07214,ko:K16147	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09994	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3416,Esterase
TLS3_k127_8516268_3	1235788.C802_00446	1.307e-80	275.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,2FMTY@200643|Bacteroidia,4AMPF@815|Bacteroidaceae	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
TLS3_k127_8516268_2	886379.AEWI01000014_gene1479	3.761e-89	300.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,2FMST@200643|Bacteroidia,3XIUV@558415|Marinilabiliaceae	976|Bacteroidetes	V	Bacitracin resistance protein BacA	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
TLS3_k127_8516268_6	1168034.FH5T_04995	4.658e-32	126.0	2E6VD@1|root,331EZ@2|Bacteria,4NUSW@976|Bacteroidetes,2FTVZ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 9.82	fjo13	-	-	-	-	-	-	-	-	-	-	-	DUF3098
TLS3_k127_8516268_4	385682.AFSL01000060_gene1816	9.557e-78	269.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,2FM17@200643|Bacteroidia,3XJE8@558415|Marinilabiliaceae	976|Bacteroidetes	D	FtsX-like permease family	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
TLS3_k127_8516268_0	596327.PORUE0001_1776	1.393e-146	471.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,2FMPE@200643|Bacteroidia,22XCN@171551|Porphyromonadaceae	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_8516268_1	927658.AJUM01000037_gene2027	3.108e-121	410.0	COG1418@1|root,COG2114@1|root,COG1418@2|Bacteria,COG2114@2|Bacteria,4PIV7@976|Bacteroidetes,2G20W@200643|Bacteroidia,3XIT9@558415|Marinilabiliaceae	976|Bacteroidetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HD
TLS3_k127_8516268_5	1168289.AJKI01000002_gene2505	1.445e-62	220.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,2G28G@200643|Bacteroidia,3XK27@558415|Marinilabiliaceae	976|Bacteroidetes	F	Ham1 family	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
TLS3_k127_8523979_0	1168034.FH5T_07405	3.051e-128	421.0	COG0038@1|root,COG0038@2|Bacteria,4NZYS@976|Bacteroidetes,2G0DB@200643|Bacteroidia	976|Bacteroidetes	P	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
TLS3_k127_8523979_6	385682.AFSL01000016_gene2009	2.559e-48	187.0	28NIY@1|root,2ZBK8@2|Bacteria,4NM7G@976|Bacteroidetes,2FQNB@200643|Bacteroidia,3XIYD@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8523979_4	385682.AFSL01000016_gene2008	5.946e-56	201.0	COG2094@1|root,COG2094@2|Bacteria,4NP22@976|Bacteroidetes,2FSNQ@200643|Bacteroidia,3XK0B@558415|Marinilabiliaceae	976|Bacteroidetes	L	Methylpurine-DNA glycosylase (MPG)	mpg	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
TLS3_k127_8523979_7	192952.MM_2722	4.965e-47	176.0	COG1513@1|root,arCOG01488@2157|Archaea,2XX3Y@28890|Euryarchaeota,2NA2H@224756|Methanomicrobia	224756|Methanomicrobia	F	MafB19-like deaminase	-	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
TLS3_k127_8523979_3	1089547.KB913013_gene2578	5.586e-69	236.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,47PQ7@768503|Cytophagia	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
TLS3_k127_8523979_5	1408473.JHXO01000001_gene1953	7.431e-51	183.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,2FSGZ@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
TLS3_k127_8523979_1	1349822.NSB1T_09340	5.621e-117	382.0	COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia,22WM5@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
TLS3_k127_8523979_2	385682.AFSL01000016_gene2004	1.209e-107	355.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,3XJ0S@558415|Marinilabiliaceae	976|Bacteroidetes	J	Elongation factor TS	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
TLS3_k127_8553656_4	1211813.CAPH01000013_gene477	1.418e-51	185.0	COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,2FSBB@200643|Bacteroidia,22UFX@171550|Rikenellaceae	976|Bacteroidetes	J	Ribosomal protein L10	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
TLS3_k127_8553656_0	411477.PARMER_01335	6.169e-118	382.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,2FNKI@200643|Bacteroidia,22X02@171551|Porphyromonadaceae	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
TLS3_k127_8553656_3	28115.HR11_04650	2.061e-73	248.0	COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,2FRYX@200643|Bacteroidia,22XQN@171551|Porphyromonadaceae	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
TLS3_k127_8553656_1	869213.JCM21142_41793	5.976e-88	293.0	COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,47KBF@768503|Cytophagia	976|Bacteroidetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
TLS3_k127_8553656_5	880526.KE386488_gene991	7.607e-17	81.0	COG0690@1|root,COG0690@2|Bacteria,4NUSJ@976|Bacteroidetes,2FV3K@200643|Bacteroidia,22VQD@171550|Rikenellaceae	976|Bacteroidetes	U	SecE/Sec61-gamma subunits of protein translocation complex	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
TLS3_k127_8553656_2	886379.AEWI01000010_gene644	4.355e-85	282.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,3XJ0R@558415|Marinilabiliaceae	976|Bacteroidetes	J	Elongation factor Tu C-terminal domain	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
TLS3_k127_8553668_2	1168034.FH5T_05300	6.343e-19	87.0	COG0535@1|root,COG0535@2|Bacteria,4NQ4R@976|Bacteroidetes,2FT2F@200643|Bacteroidia	976|Bacteroidetes	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
TLS3_k127_8553668_1	240016.ABIZ01000001_gene1149	3.863e-31	133.0	COG1146@1|root,COG1146@2|Bacteria,46TI2@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8553668_0	1168034.FH5T_10250	2.718e-84	285.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,2FKYG@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K02484,ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_8554102_5	927658.AJUM01000040_gene919	1.296e-22	98.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,2FUA3@200643|Bacteroidia,3XK4Z@558415|Marinilabiliaceae	976|Bacteroidetes	K	MraZ protein, putative antitoxin-like	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
TLS3_k127_8554102_3	1168289.AJKI01000011_gene378	7.083e-102	338.0	COG0204@1|root,COG0204@2|Bacteria,4NF25@976|Bacteroidetes,2FNJQ@200643|Bacteroidia,3XJUI@558415|Marinilabiliaceae	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TLS3_k127_8554102_1	709991.Odosp_0276	9.98e-112	369.0	COG3176@1|root,COG3176@2|Bacteria,4PKEK@976|Bacteroidetes,2FKZ3@200643|Bacteroidia,22W0V@171551|Porphyromonadaceae	976|Bacteroidetes	S	Hemolysin	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
TLS3_k127_8554102_0	1168289.AJKI01000011_gene382	1.811e-260	816.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,2FM3Y@200643|Bacteroidia,3XIMJ@558415|Marinilabiliaceae	976|Bacteroidetes	F	Class II glutamine amidotransferase	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
TLS3_k127_8554102_6	1408473.JHXO01000001_gene2450	6.702e-19	92.0	2EJD3@1|root,33D44@2|Bacteria,4NYG1@976|Bacteroidetes,2FVDP@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
TLS3_k127_8554102_2	1408473.JHXO01000001_gene2449	5.358e-103	340.0	COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,2FW6T@200643|Bacteroidia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
TLS3_k127_8554102_4	445970.ALIPUT_01575	7.842e-49	178.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,2FNP7@200643|Bacteroidia,22UPH@171550|Rikenellaceae	976|Bacteroidetes	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
TLS3_k127_8554873_0	1123248.KB893381_gene961	1.069e-101	337.0	2DB9P@1|root,2Z7Y1@2|Bacteria,4NHQN@976|Bacteroidetes,1IYRD@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_8554873_1	717231.Flexsi_1495	0.0002894	53.0	COG1242@1|root,COG1242@2|Bacteria,2GEUG@200930|Deferribacteres	200930|Deferribacteres	S	Radical_SAM C-terminal domain	-	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
TLS3_k127_8559528_2	1007103.AFHW01000017_gene5810	1.472e-13	72.0	COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli,26VIQ@186822|Paenibacillaceae	91061|Bacilli	F	phosphohydrolase	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
TLS3_k127_8559528_1	865861.AZSU01000002_gene2566	9.814e-56	209.0	COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,249JV@186801|Clostridia,36E9A@31979|Clostridiaceae	186801|Clostridia	E	lysine 2,3-aminomutase YodO family protein	ablA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
TLS3_k127_8565583_2	983544.Lacal_2138	6.382e-34	141.0	COG2378@1|root,COG2378@2|Bacteria,4NI15@976|Bacteroidetes,1HZYZ@117743|Flavobacteriia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	WYL
TLS3_k127_8565583_1	1107311.Q767_04005	2.201e-85	287.0	COG2304@1|root,COG2304@2|Bacteria,4PAWG@976|Bacteroidetes,1ID6J@117743|Flavobacteriia,2NXHH@237|Flavobacterium	976|Bacteroidetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
TLS3_k127_8565583_3	1403948.Q618_VCMC00001G1226	7.405e-33	132.0	COG0454@1|root,COG0456@2|Bacteria,2IMVD@201174|Actinobacteria,4D5W9@85005|Actinomycetales	201174|Actinobacteria	K	(GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_8565583_0	1265505.ATUG01000002_gene1675	3.524e-136	444.0	COG0420@1|root,COG0420@2|Bacteria,1MVV6@1224|Proteobacteria,42PFX@68525|delta/epsilon subdivisions,2WJS3@28221|Deltaproteobacteria,2MHR3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
TLS3_k127_8565583_4	1304885.AUEY01000004_gene971	2.945e-08	55.0	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,42NVV@68525|delta/epsilon subdivisions,2WJIZ@28221|Deltaproteobacteria,2MIHG@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM exonuclease SbcC	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
TLS3_k127_8575765_0	742817.HMPREF9449_01071	1.481e-261	810.0	COG0539@1|root,COG1185@1|root,COG0539@2|Bacteria,COG1185@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,22WN9@171551|Porphyromonadaceae	976|Bacteroidetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
TLS3_k127_8575765_8	869213.JCM21142_72764	3.36e-40	151.0	COG1366@1|root,COG1366@2|Bacteria,4NTAB@976|Bacteroidetes	976|Bacteroidetes	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
TLS3_k127_8575765_5	1211813.CAPH01000009_gene211	1.226e-91	310.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,2FM13@200643|Bacteroidia,22UNP@171550|Rikenellaceae	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
TLS3_k127_8575765_1	742725.HMPREF9450_01829	2.479e-253	788.0	COG0519@1|root,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,2FM3V@200643|Bacteroidia,22U98@171550|Rikenellaceae	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
TLS3_k127_8575765_2	880074.BARVI_08080	3.82e-167	541.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,2FN98@200643|Bacteroidia,22WA5@171551|Porphyromonadaceae	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
TLS3_k127_8575765_4	1121904.ARBP01000010_gene2228	6.683e-109	364.0	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,47MFH@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the methyltransferase superfamily	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
TLS3_k127_8575765_7	385682.AFSL01000003_gene1913	1.219e-40	157.0	2AAU0@1|root,334ZF@2|Bacteria,4NWCB@976|Bacteroidetes,2G23Y@200643|Bacteroidia,3XJI4@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8575765_6	385682.AFSL01000003_gene1912	1.842e-52	187.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,2G24U@200643|Bacteroidia,3XK3Q@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
TLS3_k127_8575765_3	1237149.C900_05256	3.44e-166	541.0	COG1131@1|root,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,47KQD@768503|Cytophagia	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,TerB
TLS3_k127_8586735_2	385682.AFSL01000087_gene712	3.161e-28	119.0	COG1595@1|root,COG1595@2|Bacteria,4NRYG@976|Bacteroidetes,2FSMX@200643|Bacteroidia,3XK1V@558415|Marinilabiliaceae	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_8586735_0	1121904.ARBP01000003_gene6277	4.703e-195	620.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,47M3C@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
TLS3_k127_8586735_1	1033732.CAHI01000030_gene920	6.508e-62	223.0	COG1082@1|root,COG1082@2|Bacteria,4NWAN@976|Bacteroidetes,2FQK1@200643|Bacteroidia	976|Bacteroidetes	G	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_8587919_2	203275.BFO_1827	3.097e-103	349.0	COG0842@1|root,COG0842@2|Bacteria,4NGFA@976|Bacteroidetes	976|Bacteroidetes	V	Transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
TLS3_k127_8587919_3	376686.Fjoh_1096	3.591e-82	280.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HZ6V@117743|Flavobacteriia,2NU6F@237|Flavobacterium	976|Bacteroidetes	V	Multidrug ABC transporter ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_8587919_1	402612.FP2275	1.397e-113	377.0	COG4990@1|root,COG4990@2|Bacteria,4NFZX@976|Bacteroidetes,1HXZ6@117743|Flavobacteriia,2NUPW@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4872)	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
TLS3_k127_8587919_5	485918.Cpin_6849	9.61e-30	123.0	2CE7N@1|root,30Q80@2|Bacteria,4NNKP@976|Bacteroidetes,1IT9G@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8587919_0	485918.Cpin_6850	4.666e-138	448.0	COG0332@1|root,COG0332@2|Bacteria,4NE5Q@976|Bacteroidetes,1IPV9@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	darB	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III_C,Thiolase_N,ketoacyl-synt
TLS3_k127_8587919_4	485918.Cpin_6851	1.106e-76	267.0	COG0716@1|root,COG0716@2|Bacteria,4NHTB@976|Bacteroidetes,1ISM3@117747|Sphingobacteriia	976|Bacteroidetes	C	Dialkylrecorsinol condensing enzyme DarA	darA	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_905898_2	471854.Dfer_2802	1.092e-39	151.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,47KKZ@768503|Cytophagia	976|Bacteroidetes	F	PFAM Na dependent nucleoside transporter	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
TLS3_k127_905898_1	742817.HMPREF9449_01252	8.262e-62	222.0	COG1376@1|root,COG1376@2|Bacteria,4P35B@976|Bacteroidetes	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
TLS3_k127_905898_0	742817.HMPREF9449_01253	6.508e-77	271.0	COG3034@1|root,COG3034@2|Bacteria,4NU5W@976|Bacteroidetes,2FZAQ@200643|Bacteroidia,2310I@171551|Porphyromonadaceae	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
TLS3_k127_905898_4	742817.HMPREF9449_01255	2.752e-16	83.0	2FFT5@1|root,347QA@2|Bacteria,4P5W2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398
TLS3_k127_908856_0	385682.AFSL01000026_gene637	2.425e-182	588.0	COG0574@1|root,COG0574@2|Bacteria,4NGSQ@976|Bacteroidetes,2FM60@200643|Bacteroidia,3XJKN@558415|Marinilabiliaceae	976|Bacteroidetes	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
TLS3_k127_914771_0	880526.KE386488_gene1777	1.692e-146	469.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,2FPKZ@200643|Bacteroidia,22U5N@171550|Rikenellaceae	976|Bacteroidetes	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
TLS3_k127_914771_1	869213.JCM21142_31010	4.576e-118	388.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,47JUG@768503|Cytophagia	976|Bacteroidetes	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
TLS3_k127_914771_5	743722.Sph21_2529	3.656e-48	184.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1IQEU@117747|Sphingobacteriia	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	fjo14	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
TLS3_k127_914771_2	927658.AJUM01000047_gene2876	3.788e-112	368.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,2FKYP@200643|Bacteroidia,3XIUC@558415|Marinilabiliaceae	976|Bacteroidetes	S	Phosphoribosyl-ATP pyrophosphohydrolase	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
TLS3_k127_914771_3	313606.M23134_04872	1.39e-98	329.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,47KSG@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS3_k127_914771_7	1408473.JHXO01000007_gene864	3.153e-37	145.0	2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,2FTAK@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG14473 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_914771_4	1168034.FH5T_01850	7.706e-77	264.0	COG1076@1|root,COG1076@2|Bacteria,4NF1B@976|Bacteroidetes,2FQ12@200643|Bacteroidia	976|Bacteroidetes	O	DnaJ domain protein	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
TLS3_k127_914771_6	391596.PBAL39_13472	1.143e-47	177.0	COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,1IS7R@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
TLS3_k127_928963_1	1408473.JHXO01000010_gene3592	2.08e-145	481.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,2FP6Z@200643|Bacteroidia	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
TLS3_k127_928963_0	385682.AFSL01000060_gene1833	5.873e-160	520.0	COG4953@1|root,COG4953@2|Bacteria,4NEG5@976|Bacteroidetes,2FNUH@200643|Bacteroidia,3XIMH@558415|Marinilabiliaceae	976|Bacteroidetes	M	Penicillin-Binding Protein C-terminus Family	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
TLS3_k127_931538_3	385682.AFSL01000088_gene870	7.632e-28	116.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,2FNGN@200643|Bacteroidia,3XJGG@558415|Marinilabiliaceae	976|Bacteroidetes	GK	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
TLS3_k127_931538_1	385682.AFSL01000088_gene871	2.172e-115	386.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,2FQZY@200643|Bacteroidia,3XJ6U@558415|Marinilabiliaceae	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
TLS3_k127_931538_0	385682.AFSL01000053_gene478	3.617e-266	829.0	COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes,2FMVI@200643|Bacteroidia,3XIUZ@558415|Marinilabiliaceae	976|Bacteroidetes	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
TLS3_k127_931538_2	927658.AJUM01000034_gene301	6.327e-47	186.0	COG4704@1|root,COG4704@2|Bacteria,4NUMP@976|Bacteroidetes,2G1EU@200643|Bacteroidia,3XM0J@558415|Marinilabiliaceae	976|Bacteroidetes	S	Fibrobacter succinogenes major domain (Fib_succ_major)	-	-	-	-	-	-	-	-	-	-	-	-	BACON,Fib_succ_major
TLS3_k127_955338_5	468059.AUHA01000002_gene1161	4.616e-35	135.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,4NFEW@976|Bacteroidetes	976|Bacteroidetes	E	Oxidoreductase NAD-binding domain protein	-	-	-	ko:K02030,ko:K03810	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	ADH_zinc_N,GFO_IDH_MocA
TLS3_k127_955338_0	468059.AUHA01000002_gene1160	3.064e-178	567.0	COG1331@1|root,COG1331@2|Bacteria,4NIPN@976|Bacteroidetes	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
TLS3_k127_955338_1	749222.Nitsa_1713	2.043e-157	505.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,42MSY@68525|delta/epsilon subdivisions,2YT5V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
TLS3_k127_955338_2	1121012.AUKX01000050_gene2531	5.087e-90	303.0	COG1922@1|root,COG1922@2|Bacteria,4NJGT@976|Bacteroidetes,1I0I3@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the glycosyltransferase 26 family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
TLS3_k127_955338_3	869213.JCM21142_41901	9.338e-48	175.0	COG0346@1|root,COG0346@2|Bacteria,4NV3A@976|Bacteroidetes	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
TLS3_k127_955338_4	1178825.ALIH01000004_gene2970	1.25e-36	148.0	COG2890@1|root,COG2890@2|Bacteria,4PKQD@976|Bacteroidetes	976|Bacteroidetes	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
TLS3_k127_973546_1	1408473.JHXO01000010_gene3763	1.485e-111	392.0	COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,2FQ6V@200643|Bacteroidia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
TLS3_k127_973546_0	927658.AJUM01000034_gene528	1.67e-155	496.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,2FMAT@200643|Bacteroidia,3XJ4C@558415|Marinilabiliaceae	976|Bacteroidetes	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
TLS3_k127_973546_4	411901.BACCAC_00033	4.858e-34	134.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,2FT27@200643|Bacteroidia,4AWD8@815|Bacteroidaceae	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
TLS3_k127_973546_2	1408473.JHXO01000001_gene1965	7.813e-97	323.0	COG0500@1|root,COG0500@2|Bacteria,4PP98@976|Bacteroidetes	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_31
TLS3_k127_973546_3	763034.HMPREF9446_01927	7.529e-44	169.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,2FNHB@200643|Bacteroidia,4AKWK@815|Bacteroidaceae	976|Bacteroidetes	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	lolE	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
TLS3_k127_991998_6	595494.Tola_1479	1.708e-12	70.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,1S4N8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
TLS3_k127_991998_3	1408473.JHXO01000008_gene2892	5.137e-79	269.0	COG2518@1|root,COG2518@2|Bacteria,4NMTP@976|Bacteroidetes,2FXTG@200643|Bacteroidia	976|Bacteroidetes	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
TLS3_k127_991998_4	926556.Echvi_3537	1.533e-69	240.0	COG0693@1|root,COG0693@2|Bacteria,4NQI1@976|Bacteroidetes,47PAI@768503|Cytophagia	976|Bacteroidetes	S	Intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
TLS3_k127_991998_5	760192.Halhy_5074	5.537e-65	229.0	COG0702@1|root,COG0702@2|Bacteria,4NG89@976|Bacteroidetes,1IS95@117747|Sphingobacteriia	976|Bacteroidetes	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
TLS3_k127_991998_1	1168034.FH5T_03980	3.682e-136	441.0	COG2010@1|root,COG2010@2|Bacteria,4PMA9@976|Bacteroidetes	976|Bacteroidetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_991998_2	1105031.HMPREF1141_2139	1.62e-86	291.0	28H95@1|root,2Z7KY@2|Bacteria,1TQTR@1239|Firmicutes,24BKB@186801|Clostridia,36DST@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
TLS3_k127_991998_0	1168034.FH5T_07495	7.621e-282	887.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,2FRJK@200643|Bacteroidia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_996440_1	742817.HMPREF9449_01672	1.468e-50	188.0	COG2122@1|root,COG2122@2|Bacteria	2|Bacteria	S	PFAM ApbE family	-	-	-	ko:K09740	-	-	-	-	ko00000	-	-	-	-
TLS3_k127_996440_2	1168034.FH5T_06665	1.972e-41	156.0	COG1145@1|root,COG1145@2|Bacteria,4NSV2@976|Bacteroidetes,2FUDP@200643|Bacteroidia	976|Bacteroidetes	C	NIL	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,NIL
TLS3_k127_996440_0	1121129.KB903359_gene1742	2.49e-103	341.0	COG1900@1|root,COG1900@2|Bacteria,4P06S@976|Bacteroidetes,2FWMQ@200643|Bacteroidia,22ZRY@171551|Porphyromonadaceae	976|Bacteroidetes	S	Homocysteine biosynthesis enzyme, sulfur-incorporation	-	-	-	-	-	-	-	-	-	-	-	-	HcyBio
## 3184 queries scanned
## Total time (seconds): 124.36529040336609
## Rate: 25.60 q/s