## Fri Nov 15 07:18:53 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin28/TLS_3_bin.15.fa -m mmseqs --itype genome -o TLS_3_bin.15 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/TLS_3_bin.15 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
TLS3_k127_1003207_2	945713.IALB_2688	2.785e-40	151.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	arsM	-	2.1.1.137,2.1.1.79	ko:K00574,ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
TLS3_k127_1003207_1	1191523.MROS_1067	1.492e-44	164.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
TLS3_k127_1003207_0	945713.IALB_2847	1.763e-197	621.0	COG0701@1|root,COG0701@2|Bacteria	2|Bacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
TLS3_k127_1044218_2	755732.Fluta_1284	1.509e-111	371.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
TLS3_k127_1044218_6	1178825.ALIH01000001_gene2581	1.558e-05	60.0	COG3227@1|root,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,1HY9Y@117743|Flavobacteriia	976|Bacteroidetes	E	Thermolysin metallopeptidase, alpha-helical domain	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C
TLS3_k127_1044218_3	760192.Halhy_1374	4.117e-62	247.0	COG2911@1|root,COG3291@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.4,5.2.1.8	ko:K01179,ko:K03768,ko:K08738	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110	3.D.4.6	GH5,GH9	-	CHU_C,PKD,PQQ,PQQ_2,SprB,fn3
TLS3_k127_1044218_4	1296416.JACB01000001_gene3149	4.495e-15	91.0	COG1874@1|root,COG3209@1|root,COG3291@1|root,COG1874@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,4NRQS@976|Bacteroidetes,1ICMF@117743|Flavobacteriia,2YKMW@290174|Aquimarina	976|Bacteroidetes	GM	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Fibrinogen_C
TLS3_k127_1044218_1	1453500.AT05_08550	1.124e-116	426.0	COG1572@1|root,COG2911@1|root,COG1572@2|Bacteria,COG2911@2|Bacteria,4NIU0@976|Bacteroidetes,1HXV1@117743|Flavobacteriia	976|Bacteroidetes	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1044218_0	143224.JQMD01000002_gene334	6.616e-134	437.0	COG3292@1|root,COG3292@2|Bacteria,4NI2T@976|Bacteroidetes,1I1KX@117743|Flavobacteriia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
TLS3_k127_10917_1	1086011.HJ01_01528	6.455e-175	559.0	COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes,1HZJI@117743|Flavobacteriia,2NYF9@237|Flavobacterium	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
TLS3_k127_10917_0	313606.M23134_07221	5.019e-203	643.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,47JMY@768503|Cytophagia	976|Bacteroidetes	Q	TIGRFAM phytoene desaturase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
TLS3_k127_10917_2	153721.MYP_4501	5.278e-97	323.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,47J9F@768503|Cytophagia	976|Bacteroidetes	I	PFAM Squalene phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
TLS3_k127_1115689_4	497965.Cyan7822_2274	7.7e-63	230.0	28J0S@1|root,2Z8XX@2|Bacteria,1G3N4@1117|Cyanobacteria,3KHGW@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1115689_3	760192.Halhy_2085	1.426e-63	232.0	COG2367@1|root,COG2367@2|Bacteria,4NH6K@976|Bacteroidetes,1INP4@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
TLS3_k127_1115689_2	1356852.N008_07390	6.43e-127	413.0	COG2159@1|root,COG2159@2|Bacteria,4NIGJ@976|Bacteroidetes,47KJH@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
TLS3_k127_1115689_1	1124780.ANNU01000025_gene3410	4.574e-141	452.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,47NRU@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
TLS3_k127_1115689_0	755732.Fluta_0001	8.308e-234	731.0	COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,1HX45@117743|Flavobacteriia,2PAFX@246874|Cryomorphaceae	976|Bacteroidetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
TLS3_k127_1128915_2	709991.Odosp_2293	6.624e-12	77.0	COG0457@1|root,COG0457@2|Bacteria,4P45T@976|Bacteroidetes,2FYEG@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1128915_0	1178825.ALIH01000003_gene2210	1.288e-104	351.0	COG0665@1|root,COG0665@2|Bacteria,4NEEY@976|Bacteroidetes,1HZ4W@117743|Flavobacteriia	976|Bacteroidetes	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
TLS3_k127_1128915_1	1121373.KB903633_gene742	1.665e-44	181.0	COG3291@1|root,COG3291@2|Bacteria,4NS69@976|Bacteroidetes,47TT9@768503|Cytophagia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_113536_5	1123248.KB893386_gene1916	1.828e-32	130.0	COG0845@1|root,COG0845@2|Bacteria,4NITE@976|Bacteroidetes,1ISHH@117747|Sphingobacteriia	976|Bacteroidetes	M	SPTR Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,HlyD_D23
TLS3_k127_113536_0	1121899.Q764_02105	4.038e-160	516.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1HX7D@117743|Flavobacteriia,2NS74@237|Flavobacterium	976|Bacteroidetes	V	Multidrug transporter MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
TLS3_k127_113536_4	1267211.KI669560_gene2598	3.977e-40	149.0	2EGEP@1|root,33A6N@2|Bacteria,4NXT1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	5.3.3.4	ko:K03464	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R06990	RC01109	ko00000,ko00001,ko00002,ko01000	-	-	-	MIase
TLS3_k127_113536_2	700598.Niako_4439	8.347e-131	428.0	COG3503@1|root,COG3503@2|Bacteria,4NFAF@976|Bacteroidetes,1IYZU@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
TLS3_k127_113536_1	1034807.FBFL15_0575	5.195e-153	486.0	COG2897@1|root,COG2897@2|Bacteria,4NF85@976|Bacteroidetes,1HYIV@117743|Flavobacteriia,2NT7P@237|Flavobacterium	976|Bacteroidetes	P	Rhodanese Homology Domain	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
TLS3_k127_113536_6	1137281.D778_01131	1.156e-21	106.0	28PUA@1|root,2ZCJB@2|Bacteria,4NMQI@976|Bacteroidetes,1I22B@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_113536_3	714943.Mucpa_0925	2.812e-129	428.0	28MZM@1|root,2ZB6A@2|Bacteria,4NH7Z@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
TLS3_k127_11463_0	1313421.JHBV01000007_gene4280	8.462e-96	334.0	COG0729@1|root,COG0729@2|Bacteria,4PKYQ@976|Bacteroidetes,1IS7K@117747|Sphingobacteriia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,ShlB
TLS3_k127_11463_1	1122179.KB890480_gene3194	2.427e-54	209.0	COG5184@1|root,COG5276@1|root,COG5184@2|Bacteria,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes	976|Bacteroidetes	E	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,MAM,TSP_3,fn3
TLS3_k127_11463_2	1223410.KN050846_gene793	0.0007293	52.0	COG3794@1|root,COG3794@2|Bacteria,4NNXS@976|Bacteroidetes,1I3WK@117743|Flavobacteriia	976|Bacteroidetes	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
TLS3_k127_115850_1	742767.HMPREF9456_03230	2.741e-31	135.0	COG3209@1|root,COG3209@2|Bacteria,4NGJF@976|Bacteroidetes,2FQPQ@200643|Bacteroidia,22VUM@171551|Porphyromonadaceae	976|Bacteroidetes	M	RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
TLS3_k127_115850_0	1120965.AUBV01000005_gene1751	4.608e-54	196.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,47NK1@768503|Cytophagia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
TLS3_k127_1197496_5	925409.KI911562_gene2624	1.108e-141	458.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1IPM2@117747|Sphingobacteriia	976|Bacteroidetes	G	COG0738 Fucose permease	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
TLS3_k127_1197496_4	1492737.FEM08_14690	2.798e-147	472.0	COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,1HXFB@117743|Flavobacteriia,2NTK7@237|Flavobacterium	976|Bacteroidetes	E	Asparaginase	aspG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
TLS3_k127_1197496_7	1202532.FF52_08104	2.337e-48	181.0	COG3142@1|root,COG3142@2|Bacteria,4NINY@976|Bacteroidetes,1I1FE@117743|Flavobacteriia,2NSMN@237|Flavobacterium	976|Bacteroidetes	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
TLS3_k127_1197496_0	1341155.FSS13T_26600	1.559e-288	915.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,2NSK3@237|Flavobacterium	976|Bacteroidetes	G	hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_92
TLS3_k127_1197496_1	929556.Solca_2813	1.284e-278	869.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,1IQVN@117747|Sphingobacteriia	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
TLS3_k127_1197496_6	865937.Gilli_1731	8.873e-55	194.0	COG0614@1|root,COG0614@2|Bacteria,4NQQ6@976|Bacteroidetes,1I4E1@117743|Flavobacteriia	976|Bacteroidetes	P	GxxExxY protein	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
TLS3_k127_1197496_3	1313421.JHBV01000142_gene1114	1.694e-211	666.0	COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,1IQNX@117747|Sphingobacteriia	976|Bacteroidetes	E	aminoacyl-histidine dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_1197496_2	509635.N824_09780	5.377e-260	805.0	COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes	976|Bacteroidetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
TLS3_k127_1203798_1	1313421.JHBV01000028_gene1857	1.135e-129	444.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
TLS3_k127_1203798_0	340177.Cag_0308	4.249e-161	529.0	28IU7@1|root,2Z8SZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1203798_6	866536.Belba_2750	1.104e-27	117.0	2EBT0@1|root,335SQ@2|Bacteria,4NVN3@976|Bacteroidetes,47T1U@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1203798_3	1123037.AUDE01000048_gene482	2.314e-66	240.0	COG0265@1|root,COG0265@2|Bacteria,4NPPM@976|Bacteroidetes,1I66Q@117743|Flavobacteriia	976|Bacteroidetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
TLS3_k127_1203798_12	643867.Ftrac_3176	2.521e-10	63.0	2A13Z@1|root,30P9V@2|Bacteria,4PBUQ@976|Bacteroidetes,47WCX@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1203798_7	269798.CHU_1187	5.627e-20	91.0	2DP5Z@1|root,330NW@2|Bacteria,4NV0Q@976|Bacteroidetes,47SP6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1203798_8	1122621.ATZA01000012_gene3169	2.716e-16	81.0	2DMPB@1|root,32SV8@2|Bacteria,4NSG4@976|Bacteroidetes,1IXV5@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1203798_9	1121373.KB903654_gene1525	7.92e-15	74.0	2DMPB@1|root,32SV8@2|Bacteria,4NSG4@976|Bacteroidetes,47SFC@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1203798_2	755732.Fluta_3041	2.682e-101	335.0	2C9V5@1|root,2Z8F9@2|Bacteria,4NG2N@976|Bacteroidetes,1HZ7U@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1203798_4	269798.CHU_1190	1.424e-39	153.0	COG1525@1|root,COG1525@2|Bacteria,4NT0S@976|Bacteroidetes,47SPN@768503|Cytophagia	976|Bacteroidetes	L	Staphylococcal nuclease homologues	lpxP	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
TLS3_k127_1203798_10	1267211.KI669560_gene994	1.138e-13	72.0	2DNTT@1|root,32Z3E@2|Bacteria,4NVJI@976|Bacteroidetes,1IZKX@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1203798_5	755732.Fluta_0582	6.789e-35	143.0	2C9V5@1|root,2Z8F9@2|Bacteria,4NG2N@976|Bacteroidetes,1HZ7U@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_120751_2	459349.CLOAM1790	5.756e-12	79.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
TLS3_k127_120751_0	1122176.KB903577_gene4851	1.278e-27	131.0	COG1361@1|root,COG3209@1|root,COG3291@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,4NDZC@976|Bacteroidetes	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
TLS3_k127_120751_1	1121481.AUAS01000003_gene3676	3.954e-21	100.0	COG2831@1|root,COG3227@1|root,COG2831@2|Bacteria,COG3227@2|Bacteria,4PKQC@976|Bacteroidetes,47SGA@768503|Cytophagia	976|Bacteroidetes	E	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M9,Peptidase_M9_N
TLS3_k127_1214951_0	1408433.JHXV01000014_gene3668	0.0	1740.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia,2PA61@246874|Cryomorphaceae	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
TLS3_k127_1214951_3	886377.Murru_1869	7.948e-54	192.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1I1X5@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
TLS3_k127_1214951_5	742817.HMPREF9449_02788	2.544e-11	70.0	COG5652@1|root,COG5652@2|Bacteria,4PA3X@976|Bacteroidetes,2FVHF@200643|Bacteroidia	976|Bacteroidetes	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
TLS3_k127_1214951_4	1168289.AJKI01000035_gene3569	3.869e-38	155.0	28P29@1|root,2ZBYD@2|Bacteria,4NMK6@976|Bacteroidetes,2FVVU@200643|Bacteroidia,3XJT8@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1214951_2	1492737.FEM08_04220	4.615e-119	400.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes	976|Bacteroidetes	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
TLS3_k127_1214951_1	1492737.FEM08_04220	9.033e-142	466.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes	976|Bacteroidetes	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
TLS3_k127_1236606_12	362418.IW19_15945	2.362e-30	123.0	COG3801@1|root,COG3801@2|Bacteria,4NSK5@976|Bacteroidetes,1IAE8@117743|Flavobacteriia,2NWR1@237|Flavobacterium	976|Bacteroidetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
TLS3_k127_1236606_9	1492737.FEM08_36420	4.637e-48	174.0	COG5646@1|root,COG5646@2|Bacteria,4NSDH@976|Bacteroidetes,1I4HD@117743|Flavobacteriia,2NW8P@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_1236606_2	1121897.AUGO01000002_gene2331	4.948e-115	377.0	28HDX@1|root,2Z7QG@2|Bacteria,4NFID@976|Bacteroidetes,1HZD2@117743|Flavobacteriia,2NWIK@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1236606_10	761193.Runsl_4429	1.004e-37	145.0	COG2259@1|root,33816@2|Bacteria,4NUVH@976|Bacteroidetes	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
TLS3_k127_1236606_0	1124780.ANNU01000067_gene428	8.967e-165	539.0	COG1835@1|root,COG1835@2|Bacteria,4NMNZ@976|Bacteroidetes,47KWV@768503|Cytophagia	976|Bacteroidetes	I	Domain of unknown function (DUF4153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
TLS3_k127_1236606_11	886379.AEWI01000013_gene2105	2.341e-37	143.0	COG2337@1|root,COG2337@2|Bacteria,4NRIX@976|Bacteroidetes	976|Bacteroidetes	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
TLS3_k127_1236606_13	866536.Belba_2374	1.16e-14	76.0	2EA6H@1|root,334B9@2|Bacteria,4NUWX@976|Bacteroidetes,47X36@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1236606_5	649349.Lbys_0952	2.123e-82	274.0	COG5649@1|root,COG5649@2|Bacteria,4NPG5@976|Bacteroidetes,47WXQ@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_1236606_7	1267211.KI669560_gene2615	5.381e-68	232.0	COG3324@1|root,COG3324@2|Bacteria,4NRUY@976|Bacteroidetes,1IYBS@117747|Sphingobacteriia	976|Bacteroidetes	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS3_k127_1236606_6	929556.Solca_3941	6.507e-69	238.0	COG1881@1|root,COG1881@2|Bacteria,4NH14@976|Bacteroidetes,1IT2Y@117747|Sphingobacteriia	976|Bacteroidetes	S	Raf kinase inhibitor-like protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
TLS3_k127_1236606_8	760192.Halhy_5197	1.197e-60	216.0	COG1670@1|root,COG1670@2|Bacteria,4NNBE@976|Bacteroidetes,1IS72@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_1236606_3	1267211.KI669560_gene341	9.796e-107	357.0	COG2603@1|root,COG2603@2|Bacteria,4NH7W@976|Bacteroidetes,1IRWP@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhodanese Homology Domain	-	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
TLS3_k127_1236606_1	1267211.KI669560_gene693	4.468e-122	400.0	COG0709@1|root,COG0709@2|Bacteria,4NI4R@976|Bacteroidetes,1INUS@117747|Sphingobacteriia	976|Bacteroidetes	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
TLS3_k127_1236606_4	762903.Pedsa_1958	1.193e-87	298.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,1IPBF@117747|Sphingobacteriia	976|Bacteroidetes	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
TLS3_k127_1237055_3	1120985.AUMI01000014_gene816	1.244e-26	120.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1UMUT@1239|Firmicutes,4H6JS@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,PfkB
TLS3_k127_1237055_0	1121456.ATVA01000017_gene120	9.221e-45	177.0	COG0438@1|root,COG0438@2|Bacteria,1Q12Q@1224|Proteobacteria,4372A@68525|delta/epsilon subdivisions,2X1TJ@28221|Deltaproteobacteria,2MFNK@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1237055_1	326298.Suden_0198	1.614e-42	165.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.265	ko:K16868	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
TLS3_k127_1237055_2	1168289.AJKI01000044_gene22	1.199e-38	152.0	2BFRM@1|root,329KE@2|Bacteria	2|Bacteria	-	-	wbmS	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1248318_4	1380384.JADN01000004_gene2126	1.801e-75	275.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
TLS3_k127_1248318_2	714943.Mucpa_3163	7.534e-134	435.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,1IQKF@117747|Sphingobacteriia	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
TLS3_k127_1248318_6	1089547.KB913013_gene2740	6.641e-51	187.0	COG1595@1|root,COG1595@2|Bacteria,4NM40@976|Bacteroidetes,47PTU@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
TLS3_k127_1248318_5	926549.KI421517_gene1374	1.759e-68	246.0	COG0265@1|root,COG0265@2|Bacteria,4NGA4@976|Bacteroidetes,47P0I@768503|Cytophagia	976|Bacteroidetes	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
TLS3_k127_1248318_8	926562.Oweho_1648	1.029e-28	119.0	2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,1I425@117743|Flavobacteriia,2PB6J@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4286)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4286
TLS3_k127_1248318_0	762903.Pedsa_0159	1.209e-179	571.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1IPGT@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
TLS3_k127_1248318_1	867902.Ornrh_0166	2.095e-138	455.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1HX2W@117743|Flavobacteriia	976|Bacteroidetes	K	RNA polymerase sigma54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
TLS3_k127_1248318_3	1122176.KB903598_gene4712	3.977e-119	409.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CW_binding_1,HYR
TLS3_k127_1248318_7	742725.HMPREF9450_00310	6.38e-41	155.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,2FNVR@200643|Bacteroidia,22U8J@171550|Rikenellaceae	976|Bacteroidetes	Q	Permease MlaE	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
TLS3_k127_1290489_0	742817.HMPREF9449_01071	1.037e-285	887.0	COG0539@1|root,COG1185@1|root,COG0539@2|Bacteria,COG1185@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,22WN9@171551|Porphyromonadaceae	976|Bacteroidetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
TLS3_k127_1290489_1	1346330.M472_13410	1.302e-168	534.0	COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,1IR3Y@117747|Sphingobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
TLS3_k127_1290489_4	755732.Fluta_3393	1.506e-95	321.0	COG4627@1|root,COG4627@2|Bacteria,4PP0V@976|Bacteroidetes,1IKE8@117743|Flavobacteriia,2PAIZ@246874|Cryomorphaceae	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_1290489_5	1122621.ATZA01000037_gene3529	1.083e-73	257.0	COG0204@1|root,COG0204@2|Bacteria,4NF25@976|Bacteroidetes,1INUG@117747|Sphingobacteriia	976|Bacteroidetes	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TLS3_k127_1290489_3	1124780.ANNU01000042_gene610	3.071e-108	360.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,47MW1@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
TLS3_k127_1290489_11	1356852.N008_13925	5.285e-09	66.0	2C85E@1|root,335NV@2|Bacteria,4NVTV@976|Bacteroidetes,47S04@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PCMD
TLS3_k127_1290489_8	929556.Solca_0668	2.311e-21	94.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,1ITTJ@117747|Sphingobacteriia	976|Bacteroidetes	K	Cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
TLS3_k127_1290489_2	1408813.AYMG01000023_gene1972	7.766e-163	520.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1INY6@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
TLS3_k127_1290489_12	1519464.HY22_02675	5.235e-08	63.0	COG2353@1|root,COG2911@1|root,COG2353@2|Bacteria,COG2911@2|Bacteria,1FF5N@1090|Chlorobi	1090|Chlorobi	U	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1290489_7	1237149.C900_03621	1.644e-31	126.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,47JMY@768503|Cytophagia	976|Bacteroidetes	Q	TIGRFAM phytoene desaturase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
TLS3_k127_1290489_6	927658.AJUM01000022_gene1094	3.704e-47	176.0	COG3652@1|root,COG3652@2|Bacteria,4NQE9@976|Bacteroidetes	976|Bacteroidetes	S	membrane	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
TLS3_k127_1290489_9	1235457.C404_19690	2.053e-14	74.0	COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria,2VXNN@28216|Betaproteobacteria,1KAB0@119060|Burkholderiaceae	28216|Betaproteobacteria	S	UPF0391 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
TLS3_k127_1290489_10	1453498.LG45_14560	8.425e-13	72.0	2DH3W@1|root,2ZYAK@2|Bacteria,4PCVZ@976|Bacteroidetes,1IDDT@117743|Flavobacteriia,2NY3B@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1301019_5	1453500.AT05_10690	7.891e-35	134.0	COG4717@1|root,COG4717@2|Bacteria,4PKS5@976|Bacteroidetes,1IJEB@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase S46	dpp11	GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
TLS3_k127_1301019_1	1168034.FH5T_03525	1.166e-74	269.0	COG3307@1|root,COG3307@2|Bacteria,4NMYT@976|Bacteroidetes	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
TLS3_k127_1301019_8	945713.IALB_0738	2.01e-05	56.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	3.1.21.3	ko:K01153,ko:K05789,ko:K07011,ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01005,ko02000,ko02048	8.A.3.1	-	-	GNVR,Wzz
TLS3_k127_1301019_0	700598.Niako_4337	5.951e-114	377.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	pqqC	-	1.3.3.11	ko:K06137,ko:K06138	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,PqqD,Radical_SAM,SPASM,TENA_THI-4
TLS3_k127_1301019_4	1237149.C900_03822	1.218e-56	210.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_1301019_3	1469557.JSWF01000031_gene2002	4.313e-61	224.0	COG0438@1|root,COG0438@2|Bacteria,4NPXB@976|Bacteroidetes,1I7TH@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
TLS3_k127_1301019_2	1122176.KB903538_gene1452	2.288e-62	233.0	28X89@1|root,2ZJ6D@2|Bacteria,4NM59@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_1301019_6	1408433.JHXV01000016_gene1847	5.215e-24	106.0	COG1708@1|root,COG1708@2|Bacteria,4NPRU@976|Bacteroidetes,1I105@117743|Flavobacteriia	976|Bacteroidetes	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
TLS3_k127_1333313_2	755732.Fluta_3173	7.076e-74	278.0	COG0419@1|root,COG1196@1|root,COG3391@1|root,COG0419@2|Bacteria,COG1196@2|Bacteria,COG3391@2|Bacteria,4PP0U@976|Bacteroidetes,1ICPT@117743|Flavobacteriia,2PBJT@246874|Cryomorphaceae	976|Bacteroidetes	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1333313_5	1461577.CCMH01000004_gene1417	3.608e-07	63.0	COG2356@1|root,COG2356@2|Bacteria,4NEGS@976|Bacteroidetes,1HWRI@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,LTD,fn3
TLS3_k127_1333313_1	1123234.AUKI01000011_gene1164	3.745e-156	503.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,1HYME@117743|Flavobacteriia	976|Bacteroidetes	Q	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_1333313_4	1121904.ARBP01000009_gene4229	3.992e-49	186.0	COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,47WA7@768503|Cytophagia	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1333313_3	1123037.AUDE01000032_gene2256	4.432e-56	198.0	28NYH@1|root,2ZBVN@2|Bacteria,4NMB2@976|Bacteroidetes,1I177@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0403 family	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
TLS3_k127_1333313_0	1089547.KB913013_gene81	1.53e-173	558.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,47M1B@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_133564_0	1122605.KB893625_gene2118	1.581e-187	603.0	COG0457@1|root,COG0457@2|Bacteria,4NDTY@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_19,TPR_8
TLS3_k127_133564_1	362418.IW19_22340	6.628e-56	205.0	2C3WA@1|root,2Z8P1@2|Bacteria,4NW8R@976|Bacteroidetes,1IADF@117743|Flavobacteriia,2NX79@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_133564_3	1202532.FF52_07389	1.773e-30	126.0	2A9CB@1|root,30YHC@2|Bacteria,4PCB9@976|Bacteroidetes,1ICY3@117743|Flavobacteriia,2NW38@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_133564_2	991.IW20_05405	1.083e-33	134.0	2DRR4@1|root,33CQD@2|Bacteria,4P6IM@976|Bacteroidetes,1ICNX@117743|Flavobacteriia,2NTWX@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
TLS3_k127_1387555_3	709991.Odosp_0916	8.35e-149	484.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,2FMUK@200643|Bacteroidia,22VY0@171551|Porphyromonadaceae	976|Bacteroidetes	V	ABC transporter, ATP-binding protein	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS3_k127_1387555_7	929556.Solca_3282	7.619e-89	298.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,1IPC1@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
TLS3_k127_1387555_5	1191523.MROS_1907	1.071e-98	333.0	COG0598@1|root,COG0598@2|Bacteria	2|Bacteria	P	Magnesium transport protein CorA	corA	GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
TLS3_k127_1387555_10	643867.Ftrac_0507	1.73e-53	190.0	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,47QDB@768503|Cytophagia	976|Bacteroidetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
TLS3_k127_1387555_12	743722.Sph21_2965	1.908e-19	89.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,1IU0V@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
TLS3_k127_1387555_2	1313301.AUGC01000001_gene1404	2.271e-155	497.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes	976|Bacteroidetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
TLS3_k127_1387555_8	762903.Pedsa_2338	2.985e-69	250.0	COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,1IRJW@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
TLS3_k127_1387555_11	1189619.pgond44_03835	7.544e-52	190.0	COG0634@1|root,COG0634@2|Bacteria,4NNIB@976|Bacteroidetes,1I22T@117743|Flavobacteriia,4C33G@83612|Psychroflexus	976|Bacteroidetes	F	Phosphoribosyl transferase domain	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
TLS3_k127_1387555_4	1120965.AUBV01000005_gene1608	2.54e-108	359.0	COG0009@1|root,COG0009@2|Bacteria,4NF5U@976|Bacteroidetes,47KX9@768503|Cytophagia	976|Bacteroidetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua5	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
TLS3_k127_1387555_6	1121957.ATVL01000014_gene1421	4.107e-98	337.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_3,Cellulase
TLS3_k127_1387555_9	153721.MYP_1243	5.396e-68	234.0	COG0245@1|root,COG0245@2|Bacteria,4NP0N@976|Bacteroidetes,47PDR@768503|Cytophagia	976|Bacteroidetes	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
TLS3_k127_1387555_1	1150600.ADIARSV_2746	6.525e-170	541.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1IPGS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
TLS3_k127_1387555_0	714943.Mucpa_1106	7.226e-182	577.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1INWD@117747|Sphingobacteriia	976|Bacteroidetes	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS3_k127_139673_0	1408473.JHXO01000010_gene3757	1.168e-146	474.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,2FS76@200643|Bacteroidia	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
TLS3_k127_139673_1	1107311.Q767_11610	5.214e-115	381.0	COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes,1HYRX@117743|Flavobacteriia,2NST0@237|Flavobacterium	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_1398850_0	1356852.N008_16460	4.027e-162	531.0	COG0497@1|root,COG0497@2|Bacteria,4PMJC@976|Bacteroidetes,47YHC@768503|Cytophagia	976|Bacteroidetes	L	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
TLS3_k127_1398850_2	755732.Fluta_0281	2.528e-61	228.0	2DKXU@1|root,30TFF@2|Bacteria,4NPBR@976|Bacteroidetes,1I8N7@117743|Flavobacteriia,2PAAX@246874|Cryomorphaceae	976|Bacteroidetes	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	ALGX
TLS3_k127_1398850_1	1121957.ATVL01000011_gene3946	1.229e-120	397.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,47KDQ@768503|Cytophagia	976|Bacteroidetes	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
TLS3_k127_1442812_3	1313421.JHBV01000030_gene2200	1.724e-18	91.0	COG1225@1|root,COG1225@2|Bacteria,4NEEA@976|Bacteroidetes,1INVF@117747|Sphingobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
TLS3_k127_1442812_0	926562.Oweho_2435	1.786e-128	419.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,1HYIB@117743|Flavobacteriia,2PAY6@246874|Cryomorphaceae	976|Bacteroidetes	E	Arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS3_k127_1442812_1	1208919.CDSE_0853	1.352e-61	219.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2VIXW@28216|Betaproteobacteria,1KQA8@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
TLS3_k127_1442812_4	1189620.AJXL01000186_gene1372	3.811e-08	61.0	2E4I5@1|root,32ZD8@2|Bacteria,4NV9B@976|Bacteroidetes,1I50D@117743|Flavobacteriia,2NUJJ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1442812_2	929556.Solca_3402	2.199e-19	92.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,1IPYG@117747|Sphingobacteriia	976|Bacteroidetes	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
TLS3_k127_1451665_1	1168034.FH5T_20510	2.155e-143	458.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,2FNVQ@200643|Bacteroidia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS3_k127_1451665_2	521097.Coch_0092	1.089e-40	160.0	COG0400@1|root,COG0400@2|Bacteria,4NF4I@976|Bacteroidetes,1HXVK@117743|Flavobacteriia,1EQA9@1016|Capnocytophaga	976|Bacteroidetes	S	phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
TLS3_k127_1451665_0	485917.Phep_1629	2.756e-235	751.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1IPGD@117747|Sphingobacteriia	976|Bacteroidetes	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
TLS3_k127_1451665_4	443254.Marpi_0225	1.183e-15	81.0	2AD7J@1|root,312WH@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
TLS3_k127_1451665_3	929556.Solca_3896	5.097e-38	146.0	COG2967@1|root,COG2967@2|Bacteria,4NNRA@976|Bacteroidetes,1ISSC@117747|Sphingobacteriia	976|Bacteroidetes	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
TLS3_k127_1453784_4	1270196.JCKI01000009_gene3353	0.0002298	52.0	COG4733@1|root,COG4733@2|Bacteria,4NPYJ@976|Bacteroidetes,1IV35@117747|Sphingobacteriia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_1453784_3	1469557.JSWF01000030_gene3511	2.244e-41	170.0	COG0457@1|root,COG2972@1|root,COG0457@2|Bacteria,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,1HXAW@117743|Flavobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,TPR_10,TPR_12,TPR_7,TPR_8
TLS3_k127_1453784_2	1349785.BAUG01000033_gene1909	1.653e-45	174.0	COG3279@1|root,COG3279@2|Bacteria,4NEXZ@976|Bacteroidetes,1HZ0B@117743|Flavobacteriia	976|Bacteroidetes	T	COG3279 Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_1453784_1	1453500.AT05_10220	3.982e-47	184.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_1453784_0	926562.Oweho_3351	3.372e-162	542.0	28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,1I791@117743|Flavobacteriia,2PA5S@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1472305_4	926556.Echvi_4121	1.533e-29	123.0	COG0723@1|root,COG0723@2|Bacteria,4NJPJ@976|Bacteroidetes	976|Bacteroidetes	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
TLS3_k127_1472305_0	700598.Niako_0791	2.794e-177	564.0	COG1730@1|root,COG1730@2|Bacteria,4PAM0@976|Bacteroidetes,1IW3E@117747|Sphingobacteriia	976|Bacteroidetes	O	unfolded protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1472305_3	1203611.KB894543_gene1877	2.37e-33	141.0	2DKY6@1|root,30V1H@2|Bacteria,4NPWS@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1472305_1	243231.GSU2357	4.745e-89	304.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,43C4Y@68525|delta/epsilon subdivisions,2X7FA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
TLS3_k127_1472305_2	929556.Solca_1268	8.027e-75	260.0	COG1284@1|root,COG1284@2|Bacteria,4NG9F@976|Bacteroidetes,1IPVB@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
TLS3_k127_147589_3	761193.Runsl_3112	3.06e-47	179.0	COG1352@1|root,COG1352@2|Bacteria,4NFDS@976|Bacteroidetes,47JV5@768503|Cytophagia	976|Bacteroidetes	NT	PFAM MCP methyltransferase CheR-type	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
TLS3_k127_147589_8	632335.Calkr_1515	1.45e-13	85.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia,42IJP@68295|Thermoanaerobacterales	186801|Clostridia	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,WG_beta_rep
TLS3_k127_147589_10	1244083.CSUNSWCD_741	3.776e-06	61.0	COG5263@1|root,COG5263@2|Bacteria,1RJ7C@1224|Proteobacteria,42UPW@68525|delta/epsilon subdivisions,2YQ1B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
TLS3_k127_147589_9	82654.Pse7367_0370	3.221e-12	77.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin,VPEP
TLS3_k127_147589_4	1499967.BAYZ01000080_gene938	1.749e-42	172.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
TLS3_k127_147589_7	1305737.JAFX01000001_gene440	5.351e-21	93.0	2DTCP@1|root,33JQV@2|Bacteria,4NZ96@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_147589_2	1121373.KB903645_gene3365	7.815e-49	194.0	COG2010@1|root,COG2010@2|Bacteria,4NU5K@976|Bacteroidetes,47VI0@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_147589_0	1123057.P872_22025	1.927e-88	294.0	COG4815@1|root,COG4815@2|Bacteria,4NQCN@976|Bacteroidetes,47Q5K@768503|Cytophagia	976|Bacteroidetes	S	MepB protein	-	-	-	-	-	-	-	-	-	-	-	-	MepB
TLS3_k127_147589_5	391587.KAOT1_20417	4.953e-35	140.0	28T03@1|root,2ZF9F@2|Bacteria,4P8BW@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_147589_1	1341155.FSS13T_23610	2.431e-76	258.0	COG3832@1|root,COG3832@2|Bacteria,4NQ55@976|Bacteroidetes,1I3E7@117743|Flavobacteriia,2NVWM@237|Flavobacterium	976|Bacteroidetes	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_147589_6	1121012.AUKX01000025_gene526	4.965e-24	101.0	COG4898@1|root,COG4898@2|Bacteria,4NQ4W@976|Bacteroidetes,1I2X2@117743|Flavobacteriia,23HGT@178469|Arenibacter	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
TLS3_k127_1489407_2	1168034.FH5T_04010	1.442e-47	177.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,2FNA8@200643|Bacteroidia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
TLS3_k127_1489407_0	1270196.JCKI01000008_gene1468	0.0	1017.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1IP28@117747|Sphingobacteriia	976|Bacteroidetes	C	malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
TLS3_k127_1489407_1	886379.AEWI01000144_gene3273	1.753e-85	295.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,2FRVJ@200643|Bacteroidia,3XIZ5@558415|Marinilabiliaceae	976|Bacteroidetes	T	GHKL domain	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_1495806_0	755732.Fluta_0748	3.357e-38	162.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_149772_2	1137281.D778_02827	3.639e-63	224.0	COG0318@1|root,COG0318@2|Bacteria,4NDXK@976|Bacteroidetes,1IJB2@117743|Flavobacteriia	976|Bacteroidetes	IQ	acyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
TLS3_k127_149772_1	926562.Oweho_0105	3.381e-99	333.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1HXGX@117743|Flavobacteriia,2PAGW@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TLS3_k127_149772_0	926549.KI421517_gene1348	2.926e-182	585.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,47JB5@768503|Cytophagia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
TLS3_k127_149772_3	880071.Fleli_0838	3.366e-47	177.0	COG2885@1|root,COG2885@2|Bacteria,4NSJW@976|Bacteroidetes,47REJ@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
TLS3_k127_149772_6	1048983.EL17_00995	0.0002688	48.0	COG3637@1|root,COG3637@2|Bacteria,4PJMS@976|Bacteroidetes,47UMR@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_149772_4	1004149.AFOE01000016_gene1572	3.313e-22	108.0	COG1670@1|root,COG1670@2|Bacteria,4NNBE@976|Bacteroidetes,1I22F@117743|Flavobacteriia	976|Bacteroidetes	J	Polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_1507857_0	760192.Halhy_5073	0.0	1358.0	COG0745@1|root,COG1352@1|root,COG2201@1|root,COG5002@1|root,COG0745@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,4PKNJ@976|Bacteroidetes,1IPG2@117747|Sphingobacteriia	976|Bacteroidetes	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_1507857_4	1086011.HJ01_01597	3.761e-85	287.0	COG1018@1|root,COG1018@2|Bacteria,4NM4J@976|Bacteroidetes,1I1RH@117743|Flavobacteriia,2NZXX@237|Flavobacterium	976|Bacteroidetes	C	FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,FAD_binding_8,NAD_binding_1
TLS3_k127_1507857_3	1492738.FEM21_23450	1.472e-108	358.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	mhpC	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
TLS3_k127_1507857_1	506534.Rhein_2111	0.0	1114.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,1WWMA@135613|Chromatiales	135613|Chromatiales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	-	-	-	-	-	-	-	-	-	-	-	-	peroxidase
TLS3_k127_1507857_2	927658.AJUM01000047_gene2906	4.444e-268	834.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes,2FMWT@200643|Bacteroidia,3XKNN@558415|Marinilabiliaceae	976|Bacteroidetes	E	Formiminotransferase domain, N-terminal subdomain	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
TLS3_k127_1513584_0	929556.Solca_1389	1.175e-212	678.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,4NEI1@976|Bacteroidetes,1IPQU@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
TLS3_k127_1513584_1	1168034.FH5T_03525	1.03e-70	257.0	COG3307@1|root,COG3307@2|Bacteria,4NMYT@976|Bacteroidetes	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
TLS3_k127_1513584_2	1453500.AT05_07465	3.291e-22	107.0	COG3206@1|root,COG3206@2|Bacteria,4NSFM@976|Bacteroidetes	976|Bacteroidetes	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1521584_1	402612.FP1890	3.471e-39	147.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia,2NTC4@237|Flavobacterium	976|Bacteroidetes	O	peptidylprolyl isomerase	ppiB	-	5.2.1.8	ko:K01802,ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,Pro_isomerase
TLS3_k127_1521584_0	1408433.JHXV01000029_gene3073	2.026e-113	390.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IMQK@117743|Flavobacteriia,2PBES@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
TLS3_k127_15303_3	1218108.KB908291_gene924	1.036e-14	74.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,4NI68@976|Bacteroidetes,1HXAQ@117743|Flavobacteriia	976|Bacteroidetes	CI	phenylacetic acid degradation protein paaN	paaN	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,DUF1569,MaoC_dehydratas
TLS3_k127_15303_1	1348583.ATLH01000013_gene3077	1.729e-39	150.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,1I2YH@117743|Flavobacteriia,1F985@104264|Cellulophaga	976|Bacteroidetes	J	Endoribonuclease L-PSP	tdcF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
TLS3_k127_15303_2	1122605.KB893644_gene1518	6.486e-21	95.0	COG0724@1|root,COG0724@2|Bacteria,4NT1J@976|Bacteroidetes,1ITMI@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
TLS3_k127_15303_0	1124780.ANNU01000038_gene197	4.929e-237	741.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,47ME8@768503|Cytophagia	976|Bacteroidetes	EF	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
TLS3_k127_1532182_2	1296416.JACB01000042_gene1798	2.071e-16	81.0	2APQJ@1|root,31EUD@2|Bacteria,4NNU5@976|Bacteroidetes,1I2CM@117743|Flavobacteriia,2YITM@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1532182_0	269798.CHU_2567	6.988e-23	100.0	COG3530@1|root,COG3530@2|Bacteria,4NUSP@976|Bacteroidetes,47RWJ@768503|Cytophagia	976|Bacteroidetes	S	Putative quorum-sensing-regulated virulence factor	-	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
TLS3_k127_1532182_1	984262.SGRA_0732	4.389e-21	108.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1J0Y4@117747|Sphingobacteriia	976|Bacteroidetes	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
TLS3_k127_1543812_1	1408433.JHXV01000015_gene1734	8.439e-121	404.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,4P03T@976|Bacteroidetes	976|Bacteroidetes	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
TLS3_k127_1543812_3	946077.W5A_10467	2.208e-25	121.0	28MEY@1|root,2ZASH@2|Bacteria,4NG12@976|Bacteroidetes,1I8JG@117743|Flavobacteriia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TLS3_k127_1543812_4	1168034.FH5T_10655	1.53e-24	108.0	COG0824@1|root,COG0824@2|Bacteria,4NQ3I@976|Bacteroidetes,2FRZ4@200643|Bacteroidia	976|Bacteroidetes	S	acyl-CoA thioester hydrolase, YbgC YbaW family	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
TLS3_k127_1543812_2	1127692.HMPREF9075_01212	8.471e-92	312.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1HWSU@117743|Flavobacteriia,1EQDX@1016|Capnocytophaga	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
TLS3_k127_1543812_0	468059.AUHA01000002_gene1138	1.802e-149	476.0	COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,1IPV3@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
TLS3_k127_1562452_5	926562.Oweho_1735	5.521e-14	82.0	COG0438@1|root,COG3307@1|root,COG0438@2|Bacteria,COG3307@2|Bacteria,4PIFR@976|Bacteroidetes,1IF9I@117743|Flavobacteriia,2PBZW@246874|Cryomorphaceae	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
TLS3_k127_1562452_1	1453498.LG45_02435	3.612e-81	290.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1HXKD@117743|Flavobacteriia,2NT69@237|Flavobacterium	976|Bacteroidetes	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_1562452_3	869213.JCM21142_93830	2.511e-45	171.0	COG0224@1|root,COG0224@2|Bacteria,4NM5H@976|Bacteroidetes,47Q4T@768503|Cytophagia	976|Bacteroidetes	C	PFAM WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
TLS3_k127_1562452_4	926549.KI421517_gene3829	4.377e-36	149.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,47JH7@768503|Cytophagia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
TLS3_k127_1562452_0	1454007.JAUG01000124_gene1073	8.375e-112	383.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1IRAK@117747|Sphingobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
TLS3_k127_1562452_2	1189612.A33Q_0850	8.25e-81	272.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,47MA2@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
TLS3_k127_1565591_0	755732.Fluta_3275	0.0	1172.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1HWVR@117743|Flavobacteriia,2PAAQ@246874|Cryomorphaceae	976|Bacteroidetes	O	ATPase family associated with various cellular activities (AAA)	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
TLS3_k127_1565591_3	1041826.FCOL_07305	6.697e-28	115.0	COG2127@1|root,COG2127@2|Bacteria,4NS8R@976|Bacteroidetes,1I3WR@117743|Flavobacteriia,2NWUE@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the ClpS family	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
TLS3_k127_1565591_1	385682.AFSL01000064_gene1700	1.417e-85	291.0	COG0501@1|root,COG0501@2|Bacteria,4NE0J@976|Bacteroidetes,2FQJ1@200643|Bacteroidia,3XJXP@558415|Marinilabiliaceae	976|Bacteroidetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TLS3_k127_1565591_2	1453500.AT05_04480	2.259e-30	123.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,fn3
TLS3_k127_1568779_2	1408473.JHXO01000006_gene1066	4.64e-82	286.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,2FM2K@200643|Bacteroidia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
TLS3_k127_1568779_0	1120966.AUBU01000012_gene159	1.46e-186	588.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,47JEY@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
TLS3_k127_1568779_4	755732.Fluta_1675	1.013e-54	199.0	COG0637@1|root,COG0637@2|Bacteria,4NID6@976|Bacteroidetes,1HZWD@117743|Flavobacteriia,2PBQZ@246874|Cryomorphaceae	976|Bacteroidetes	S	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	3.1.3.23	ko:K19270	-	-	-	-	ko00000,ko01000	-	-	-	HAD_2
TLS3_k127_1568779_1	1137281.D778_00762	2.582e-82	287.0	COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,1HXJW@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_1568779_3	984262.SGRA_4178	2.809e-58	207.0	COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes,1IQE8@117747|Sphingobacteriia	976|Bacteroidetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_160489_2	1408473.JHXO01000006_gene1089	2.171e-62	226.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,2FMM9@200643|Bacteroidia	976|Bacteroidetes	O	Psort location Cytoplasmic, score 8.96	gldB	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_160489_7	620914.JH621255_gene679	0.0002762	46.0	2DC8R@1|root,2ZD9I@2|Bacteria,4P83B@976|Bacteroidetes,1IBX1@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_160489_5	1121481.AUAS01000013_gene4294	1.136e-18	88.0	COG3668@1|root,COG3668@2|Bacteria,4NXUR@976|Bacteroidetes,47SX3@768503|Cytophagia	976|Bacteroidetes	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
TLS3_k127_160489_4	1484460.JSWG01000012_gene1574	2.769e-30	124.0	COG5580@1|root,COG5580@2|Bacteria,4PK53@976|Bacteroidetes,1I3SX@117743|Flavobacteriia	976|Bacteroidetes	O	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_160489_0	929556.Solca_4330	7.4e-323	997.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,1INUN@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
TLS3_k127_160489_1	269798.CHU_1561	7.048e-79	284.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4P1P3@976|Bacteroidetes,47THG@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
TLS3_k127_160489_6	1121904.ARBP01000002_gene7059	3.453e-05	51.0	COG3291@1|root,COG3291@2|Bacteria,4NV3K@976|Bacteroidetes,47W7K@768503|Cytophagia	976|Bacteroidetes	C	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_160489_3	468059.AUHA01000002_gene308	3.767e-59	208.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1IR18@117747|Sphingobacteriia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
TLS3_k127_1617716_0	269798.CHU_3458	4.402e-113	369.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,47J97@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_1617716_1	1189619.pgond44_03523	8.969e-26	117.0	COG2304@1|root,COG2304@2|Bacteria,4NKZ6@976|Bacteroidetes,1IFZZ@117743|Flavobacteriia,4C41B@83612|Psychroflexus	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_1617716_2	1189612.A33Q_0763	7.136e-15	74.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,47K3E@768503|Cytophagia	976|Bacteroidetes	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
TLS3_k127_1643530_0	391587.KAOT1_15092	2.645e-166	533.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1HWS4@117743|Flavobacteriia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
TLS3_k127_1643530_1	468059.AUHA01000008_gene2748	1.182e-65	235.0	COG0642@1|root,COG2205@2|Bacteria,4NK58@976|Bacteroidetes,1IPNM@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_1643530_2	1173021.ALWA01000033_gene4265	1.113e-53	201.0	COG0614@1|root,COG0614@2|Bacteria,1G37R@1117|Cyanobacteria	1117|Cyanobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
TLS3_k127_1654398_1	1380384.JADN01000003_gene530	1.838e-89	310.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1HWXT@117743|Flavobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1654398_0	743722.Sph21_0739	8.89e-119	393.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1IQD9@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	-	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS3_k127_1678630_2	1349785.BAUG01000053_gene2402	3.522e-13	74.0	COG0801@1|root,COG1428@1|root,COG0801@2|Bacteria,COG1428@2|Bacteria,4NGE8@976|Bacteroidetes,1HWTH@117743|Flavobacteriia	976|Bacteroidetes	FH	Pfam 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
TLS3_k127_1678630_1	391587.KAOT1_13337	6.269e-22	111.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HYTX@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
TLS3_k127_1678630_0	395494.Galf_1844	2.487e-26	111.0	2AGY9@1|root,3176X@2|Bacteria	2|Bacteria	S	Gliding motility-associated protein GldC	gldC	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1678630_3	688246.Premu_2561	4.252e-10	62.0	COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,2FSR0@200643|Bacteroidia	976|Bacteroidetes	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
TLS3_k127_1683765_0	1229276.DI53_2266	1.205e-50	186.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1IQ3B@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
TLS3_k127_1683765_3	762982.HMPREF9442_03091	5.553e-13	73.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4
TLS3_k127_1683765_1	1123248.KB893337_gene2408	1.419e-24	109.0	COG0729@1|root,COG3210@1|root,COG0729@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Bac_surface_Ag,Peptidase_S74
TLS3_k127_1683765_2	319236.JCM19294_1582	5.793e-20	103.0	COG2972@1|root,COG2972@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
TLS3_k127_168456_0	1392488.JHZY01000002_gene534	2.17e-22	111.0	COG0515@1|root,COG0515@2|Bacteria,4NJH8@976|Bacteroidetes,1I4US@117743|Flavobacteriia	976|Bacteroidetes	KLT	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
TLS3_k127_1702366_0	926551.KB900715_gene2089	5.842e-103	345.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1HY00@117743|Flavobacteriia,1EQH9@1016|Capnocytophaga	976|Bacteroidetes	L	a g-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
TLS3_k127_1702366_3	1408813.AYMG01000014_gene1593	1.274e-39	153.0	COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes,1IY6E@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Lipid polyisoprenoid-binding, YceI-like	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_1702366_2	1121373.KB903642_gene3696	2.088e-68	244.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47NZ9@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1702366_1	385682.AFSL01000096_gene594	1.639e-90	310.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,2FMX9@200643|Bacteroidia,3XIXK@558415|Marinilabiliaceae	976|Bacteroidetes	H	Uroporphyrinogen-III synthase HemD	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
TLS3_k127_1702366_4	1120951.AUBG01000015_gene3497	6.698e-14	75.0	COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,1I41Y@117743|Flavobacteriia	976|Bacteroidetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
TLS3_k127_172147_1	1305737.JAFX01000001_gene447	2.929e-78	263.0	COG0419@1|root,COG0613@1|root,COG0419@2|Bacteria,COG0613@2|Bacteria,4NIW1@976|Bacteroidetes	976|Bacteroidetes	L	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_172147_2	1218108.KB908291_gene869	6.442e-69	246.0	2E1ZR@1|root,32X84@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4935)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4935
TLS3_k127_172147_0	1121899.Q764_03310	4.005e-95	325.0	2937M@1|root,2ZQQJ@2|Bacteria,4NPSN@976|Bacteroidetes,1IMU0@117743|Flavobacteriia,2NURV@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_172147_3	700598.Niako_5072	1.814e-38	153.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,1IT3A@117747|Sphingobacteriia	976|Bacteroidetes	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_172147_4	1296416.JACB01000006_gene569	2.001e-27	122.0	COG4585@1|root,COG4585@2|Bacteria,4NN4R@976|Bacteroidetes,1I49A@117743|Flavobacteriia,2YHXB@290174|Aquimarina	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TLS3_k127_1725250_1	688270.Celal_0279	2.702e-37	144.0	COG3437@1|root,COG3437@2|Bacteria,4P49T@976|Bacteroidetes,1I2Y1@117743|Flavobacteriia,1F9GJ@104264|Cellulophaga	976|Bacteroidetes	T	SMART Signal transduction response regulator, receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_1725250_0	1048983.EL17_02130	5.461e-80	273.0	COG4251@1|root,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,47PUU@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,PAS_3,PAS_4,PAS_9
TLS3_k127_172861_15	471854.Dfer_3896	3.943e-07	54.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,47KJD@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TLS3_k127_172861_4	929556.Solca_3728	2.231e-158	512.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1IPJW@117747|Sphingobacteriia	976|Bacteroidetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
TLS3_k127_172861_0	468059.AUHA01000002_gene1094	3.778e-242	763.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
TLS3_k127_172861_12	929556.Solca_3730	7.905e-33	129.0	COG0713@1|root,COG0713@2|Bacteria,4NTBP@976|Bacteroidetes,1ISXN@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
TLS3_k127_172861_10	153721.MYP_731	8.329e-48	176.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,47PS7@768503|Cytophagia	976|Bacteroidetes	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
TLS3_k127_172861_7	755732.Fluta_1965	3.75e-83	280.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,1I2F9@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
TLS3_k127_172861_5	1121373.KB903623_gene2358	2.553e-128	419.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,47K9J@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
TLS3_k127_172861_3	929556.Solca_3734	3.39e-159	506.0	COG1034@1|root,COG1034@2|Bacteria,4NH3P@976|Bacteroidetes,1IR1J@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,NADH-G_4Fe-4S_3
TLS3_k127_172861_13	667015.Bacsa_1758	2.719e-25	110.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,2FM72@200643|Bacteroidia,4AKT0@815|Bacteroidaceae	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_172861_1	1408813.AYMG01000036_gene3284	1.65e-224	702.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1INS2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
TLS3_k127_172861_8	153721.MYP_736	7.131e-63	221.0	COG1905@1|root,COG1905@2|Bacteria,4NHIQ@976|Bacteroidetes,47JBB@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM NADH-quinone oxidoreductase, E subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
TLS3_k127_172861_2	1034807.FBFL15_0629	8.432e-201	631.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1HZMG@117743|Flavobacteriia,2NTNC@237|Flavobacterium	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
TLS3_k127_172861_9	153721.MYP_738	5.974e-51	185.0	COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,47PAN@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
TLS3_k127_172861_6	1453498.LG45_05435	2.741e-93	308.0	COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,1I0R8@117743|Flavobacteriia,2NSHX@237|Flavobacterium	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
TLS3_k127_172861_11	929556.Solca_3740	7.025e-46	168.0	COG0838@1|root,COG0838@2|Bacteria,4NQJB@976|Bacteroidetes,1ISVI@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
TLS3_k127_172861_14	1313172.YM304_34210	1.403e-24	109.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	lytH	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
TLS3_k127_1756021_2	468059.AUHA01000002_gene622	3.109e-06	56.0	2F8TK@1|root,3415N@2|Bacteria,4P43P@976|Bacteroidetes,1IYQK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1756021_1	247490.KSU1_B0531	1.313e-28	124.0	COG1262@1|root,COG1262@2|Bacteria,2J3GG@203682|Planctomycetes	203682|Planctomycetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TLS3_k127_1756021_0	1487953.JMKF01000088_gene5446	2.76e-61	231.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1G08F@1117|Cyanobacteria,1H8J6@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,SBBP
TLS3_k127_1758727_2	1121373.KB903662_gene54	6.323e-41	155.0	COG2081@1|root,COG2081@2|Bacteria,4NFQ9@976|Bacteroidetes,47KHX@768503|Cytophagia	976|Bacteroidetes	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
TLS3_k127_1758727_0	1111730.ATTM01000003_gene542	2.643e-98	328.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,1HWQA@117743|Flavobacteriia,2NSJX@237|Flavobacterium	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
TLS3_k127_1758727_4	485917.Phep_0322	2.164e-07	56.0	2ACEV@1|root,3120D@2|Bacteria,4PGV7@976|Bacteroidetes,1IUFE@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1758727_3	531844.FIC_01200	1.425e-20	108.0	COG1345@1|root,COG3209@1|root,COG1345@2|Bacteria,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,4074H@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,SprB
TLS3_k127_1758727_1	1380384.JADN01000004_gene2126	1.591e-48	198.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
TLS3_k127_1791956_0	1237149.C900_03657	1.139e-288	908.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,47K9H@768503|Cytophagia	976|Bacteroidetes	L	DNA-directed DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
TLS3_k127_1796771_0	641524.ADICYQ_5807	9.935e-304	940.0	COG0332@1|root,COG0332@2|Bacteria,4NE5Q@976|Bacteroidetes,47KWN@768503|Cytophagia	976|Bacteroidetes	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C,ketoacyl-synt
TLS3_k127_1796771_1	880070.Cycma_2248	2.48e-155	494.0	2CIYT@1|root,2Z7R8@2|Bacteria,4NIUR@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1796771_2	1094466.KQS_04885	6.213e-146	466.0	COG3177@1|root,COG3177@2|Bacteria,4NHPW@976|Bacteroidetes,1HWY1@117743|Flavobacteriia,2NVUA@237|Flavobacterium	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
TLS3_k127_1796771_5	929704.Myrod_3668	3.036e-75	254.0	COG5646@1|root,COG5646@2|Bacteria,4NNPA@976|Bacteroidetes,1I1Y8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_1796771_7	886379.AEWI01000047_gene3087	1.815e-19	99.0	COG0457@1|root,COG2849@1|root,COG0457@2|Bacteria,COG2849@2|Bacteria,4NP5N@976|Bacteroidetes,2FS0W@200643|Bacteroidia	976|Bacteroidetes	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
TLS3_k127_1796771_4	760192.Halhy_4522	1.366e-103	345.0	COG1235@1|root,COG1235@2|Bacteria,4NGB4@976|Bacteroidetes,1IX4R@117747|Sphingobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
TLS3_k127_1796771_3	1122176.KB903598_gene4584	8.099e-118	391.0	COG1104@1|root,COG1104@2|Bacteria,4NG58@976|Bacteroidetes,1IQ14@117747|Sphingobacteriia	976|Bacteroidetes	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
TLS3_k127_1796771_6	1453498.LG45_02920	2.703e-68	242.0	COG0697@1|root,COG0697@2|Bacteria,4NE8D@976|Bacteroidetes,1HXCW@117743|Flavobacteriia,2NTBE@237|Flavobacterium	976|Bacteroidetes	EG	permease	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_179755_0	1408433.JHXV01000012_gene3977	2.978e-98	347.0	COG1404@1|root,COG1404@2|Bacteria,4NTWX@976|Bacteroidetes,1I4GV@117743|Flavobacteriia,2PBAJ@246874|Cryomorphaceae	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_179755_1	1249997.JHZW01000003_gene3013	5.635e-49	182.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,1HXBN@117743|Flavobacteriia,2PGVJ@252356|Maribacter	976|Bacteroidetes	J	N-6 DNA Methylase	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
TLS3_k127_18067_1	509635.N824_26605	3.11e-81	278.0	COG3823@1|root,COG3823@2|Bacteria,4P2CR@976|Bacteroidetes,1IXIA@117747|Sphingobacteriia	976|Bacteroidetes	O	Glutamine cyclotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2
TLS3_k127_18067_0	313594.PI23P_04492	1.151e-82	288.0	COG0644@1|root,COG0644@2|Bacteria,4NDTU@976|Bacteroidetes,1HYHZ@117743|Flavobacteriia,3VW4I@52959|Polaribacter	976|Bacteroidetes	C	Lycopene cyclase protein	crtY	-	5.5.1.19	ko:K06443	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R03824,R04801,R05341,R06962,R07856	RC01004,RC01964	ko00000,ko00001,ko00002,ko01000	-	-	-	Lycopene_cycl
TLS3_k127_18067_2	938709.AUSH02000045_gene477	6.186e-70	239.0	COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
TLS3_k127_18067_3	938709.AUSH02000045_gene478	3.266e-56	203.0	COG2324@1|root,COG2324@2|Bacteria,4NQR7@976|Bacteroidetes	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
TLS3_k127_18067_4	755732.Fluta_0097	1.478e-11	64.0	COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes,1HZJI@117743|Flavobacteriia,2PBE3@246874|Cryomorphaceae	976|Bacteroidetes	H	PFAM Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
TLS3_k127_1813443_0	1120966.AUBU01000005_gene3824	4.853e-137	454.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,47K5C@768503|Cytophagia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
TLS3_k127_1813443_2	762903.Pedsa_2077	1.193e-47	180.0	COG0428@1|root,COG0428@2|Bacteria,4NG1R@976|Bacteroidetes,1ITHR@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM zinc iron permease	-	-	-	-	-	-	-	-	-	-	-	-	Zip
TLS3_k127_1813443_1	714943.Mucpa_4954	1.929e-66	234.0	COG0500@1|root,COG0500@2|Bacteria,4NFKM@976|Bacteroidetes,1IPHK@117747|Sphingobacteriia	976|Bacteroidetes	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31,TehB
TLS3_k127_1813443_3	1408433.JHXV01000026_gene3026	2.094e-06	58.0	COG0419@1|root,COG0823@1|root,COG0419@2|Bacteria,COG0823@2|Bacteria,4P15I@976|Bacteroidetes,1IE72@117743|Flavobacteriia,2PBDD@246874|Cryomorphaceae	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
TLS3_k127_1825600_3	984262.SGRA_0716	9.189e-42	156.0	COG1858@1|root,COG1858@2|Bacteria,4NEKS@976|Bacteroidetes,1IQPC@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
TLS3_k127_1825600_1	1197477.IA57_07120	2.141e-90	303.0	COG1878@1|root,COG1878@2|Bacteria,4NFXM@976|Bacteroidetes,1HWQP@117743|Flavobacteriia	976|Bacteroidetes	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
TLS3_k127_1825600_0	269798.CHU_1289	5.825e-149	475.0	COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,47KE8@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
TLS3_k127_1825600_2	1123248.KB893322_gene568	8.882e-53	213.0	COG1361@1|root,COG3291@1|root,COG4386@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG4386@2|Bacteria,4NDZC@976|Bacteroidetes,1IV4S@117747|Sphingobacteriia	976|Bacteroidetes	M	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB,TIG
TLS3_k127_1844686_8	743722.Sph21_2410	3.212e-80	269.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1IQRC@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
TLS3_k127_1844686_11	926562.Oweho_0387	7.806e-63	232.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1HY2Q@117743|Flavobacteriia,2PBZ4@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6
TLS3_k127_1844686_13	755732.Fluta_3514	2.203e-34	138.0	2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,1I1XW@117743|Flavobacteriia,2PB06@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1844686_3	1408433.JHXV01000006_gene2777	7.975e-179	570.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,1HZDM@117743|Flavobacteriia,2PACK@246874|Cryomorphaceae	976|Bacteroidetes	E	Aminopeptidase P, N-terminal domain	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
TLS3_k127_1844686_7	509635.N824_03160	1.474e-85	287.0	28H95@1|root,2Z7KY@2|Bacteria,4NG37@976|Bacteroidetes,1IPRY@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
TLS3_k127_1844686_10	926549.KI421517_gene2090	1.632e-67	253.0	COG2706@1|root,COG2706@2|Bacteria,4PMCI@976|Bacteroidetes,47Y0V@768503|Cytophagia	976|Bacteroidetes	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1844686_2	509635.N824_05040	1.341e-239	760.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF7I@976|Bacteroidetes,1IRKI@117747|Sphingobacteriia	976|Bacteroidetes	E	peptidase	ptpA	-	3.4.14.12,3.4.14.5	ko:K01278,ko:K18574	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
TLS3_k127_1844686_1	1201288.M900_A0067	0.0	1060.0	COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,42PUK@68525|delta/epsilon subdivisions,2MSNN@213481|Bdellovibrionales,2WIN4@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
TLS3_k127_1844686_6	870187.Thini_3060	1.705e-100	340.0	COG1373@1|root,COG1373@2|Bacteria,1RAB0@1224|Proteobacteria,1SA91@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
TLS3_k127_1844686_14	1450525.JATV01000012_gene3053	1.076e-23	102.0	2E5CT@1|root,3304V@2|Bacteria,4NUT8@976|Bacteroidetes,1I511@117743|Flavobacteriia,2NXFI@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1844686_12	518766.Rmar_0035	4.401e-38	149.0	COG1225@1|root,COG1225@2|Bacteria,4NMEK@976|Bacteroidetes	976|Bacteroidetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TLS3_k127_1844686_9	153721.MYP_2118	3.208e-75	282.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,47KTA@768503|Cytophagia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
TLS3_k127_1844686_5	1408433.JHXV01000013_gene2586	6.684e-124	414.0	COG4191@1|root,COG4191@2|Bacteria,4NEMP@976|Bacteroidetes,1HY7G@117743|Flavobacteriia,2PAKB@246874|Cryomorphaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	vicK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
TLS3_k127_1844686_4	929562.Emtol_1511	2.462e-133	428.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,47KHR@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
TLS3_k127_1844686_0	929703.KE386491_gene3971	0.0	1164.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,47JE5@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
TLS3_k127_1846347_1	755732.Fluta_2051	1.67e-77	272.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1HZEV@117743|Flavobacteriia,2PBMM@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
TLS3_k127_1846347_2	1453500.AT05_09095	7.533e-69	239.0	COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,1I20V@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
TLS3_k127_1846347_0	755732.Fluta_2053	3.213e-93	320.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia,2PA6D@246874|Cryomorphaceae	976|Bacteroidetes	DM	Chain length determinant protein	wzc	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
TLS3_k127_1852923_1	1408473.JHXO01000005_gene1442	2.651e-178	571.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,2FNRC@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
TLS3_k127_1852923_3	1121094.KB894643_gene1838	1.799e-75	261.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,2FP2H@200643|Bacteroidia,4AK8G@815|Bacteroidaceae	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
TLS3_k127_1852923_0	762903.Pedsa_2486	5.264e-180	582.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1IQFU@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
TLS3_k127_1852923_4	929556.Solca_4164	1.599e-73	253.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,1ISBF@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
TLS3_k127_1852923_2	1121373.KB903622_gene2826	2.291e-125	411.0	COG1123@1|root,COG4172@2|Bacteria,4NGDP@976|Bacteroidetes,47KUE@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the ABC transporter superfamily	gsiA	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
TLS3_k127_1857725_1	1121859.KB890739_gene2695	2.967e-66	235.0	COG4185@1|root,COG4185@2|Bacteria,4NRJJ@976|Bacteroidetes,47QTA@768503|Cytophagia	976|Bacteroidetes	S	zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
TLS3_k127_1857725_0	1408303.JNJJ01000075_gene3378	2.419e-78	268.0	COG0732@1|root,COG0732@2|Bacteria,1UZGE@1239|Firmicutes,4HCYM@91061|Bacilli,1ZGYQ@1386|Bacillus	91061|Bacilli	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
TLS3_k127_1869943_0	927658.AJUM01000042_gene1602	2.895e-36	151.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_1869943_2	391603.FBALC1_12447	2.287e-16	91.0	COG1572@1|root,COG1572@2|Bacteria,4PMN9@976|Bacteroidetes,1IJVH@117743|Flavobacteriia	976|Bacteroidetes	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
TLS3_k127_1869943_1	1121098.HMPREF1534_03742	2.86e-35	141.0	COG1572@1|root,COG1572@2|Bacteria,4PMN9@976|Bacteroidetes	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
TLS3_k127_1890011_1	714943.Mucpa_0680	7.946e-07	59.0	2AT0W@1|root,31IGS@2|Bacteria,4PK6Z@976|Bacteroidetes,1IZH8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1890011_0	929703.KE386491_gene122	6.276e-24	110.0	COG4585@1|root,COG4585@2|Bacteria,4NNE1@976|Bacteroidetes,47PFT@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TLS3_k127_1890721_16	1121896.JMLU01000021_gene744	3.322e-05	54.0	COG3227@1|root,COG4935@1|root,COG3227@2|Bacteria,COG4935@2|Bacteria,4NQ5Q@976|Bacteroidetes,1IKK2@117743|Flavobacteriia,2NUUQ@237|Flavobacterium	976|Bacteroidetes	E	Peptidase propeptide and YPEB domain	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	FTP,PepSY,Peptidase_M36,Peptidase_M4
TLS3_k127_1890721_15	313596.RB2501_10432	2.419e-05	57.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes,1HXSH@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM Outer membrane protein, OmpA MotB, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
TLS3_k127_1890721_12	1123248.KB893318_gene4168	3.664e-19	102.0	COG3291@1|root,COG3291@2|Bacteria,4NPDM@976|Bacteroidetes,1IW61@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_1890721_10	926556.Echvi_2741	3.532e-32	128.0	COG2827@1|root,COG2827@2|Bacteria,4NUYX@976|Bacteroidetes,47RSS@768503|Cytophagia	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
TLS3_k127_1890721_1	1111730.ATTM01000002_gene1213	4.969e-170	553.0	COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,1HYJM@117743|Flavobacteriia,2NUW9@237|Flavobacterium	976|Bacteroidetes	V	Multidrug ABC transporter ATPase	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
TLS3_k127_1890721_14	743722.Sph21_0328	1.933e-18	87.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,1IU87@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
TLS3_k127_1890721_11	592029.DDD_1229	9.311e-30	125.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,1I17C@117743|Flavobacteriia,3HK7R@363408|Nonlabens	976|Bacteroidetes	S	Uncharacterized ACR, COG1399	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
TLS3_k127_1890721_13	313603.FB2170_06265	1.165e-18	86.0	COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,1I53M@117743|Flavobacteriia,2PHNT@252356|Maribacter	976|Bacteroidetes	J	Ribosomal L32p protein family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
TLS3_k127_1890721_9	317936.Nos7107_3218	1.715e-39	162.0	COG2202@1|root,COG3920@1|root,COG2202@2|Bacteria,COG3920@2|Bacteria,1GHDM@1117|Cyanobacteria,1HJGT@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GGDEF,HATPase_c,HisKA_2,PAS_3,PAS_4,PAS_9
TLS3_k127_1890721_6	929556.Solca_3252	8.139e-131	424.0	COG0416@1|root,COG0416@2|Bacteria,4NHEX@976|Bacteroidetes,1IPMW@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
TLS3_k127_1890721_4	1279009.ADICEAN_02143	1.698e-152	488.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,47KV4@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
TLS3_k127_1890721_0	643867.Ftrac_3705	3.989e-203	637.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,47MGP@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_1890721_3	755732.Fluta_1630	6.252e-158	518.0	COG3210@1|root,COG5184@1|root,COG3210@2|Bacteria,COG5184@2|Bacteria,4NIDX@976|Bacteroidetes,1I0AY@117743|Flavobacteriia,2PBAP@246874|Cryomorphaceae	976|Bacteroidetes	U	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_1890721_7	313594.PI23P_08425	7.371e-86	294.0	COG3420@1|root,COG3420@2|Bacteria,4NMRB@976|Bacteroidetes,1I904@117743|Flavobacteriia	976|Bacteroidetes	P	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494
TLS3_k127_1890721_5	643867.Ftrac_2856	3.248e-135	439.0	COG0346@1|root,COG0346@2|Bacteria,4NDVG@976|Bacteroidetes,47MTQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
TLS3_k127_1890721_2	873517.HMPREF1977_1405	2.025e-167	531.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,1HWK5@117743|Flavobacteriia,1EQVJ@1016|Capnocytophaga	976|Bacteroidetes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
TLS3_k127_1895718_1	269798.CHU_2796	4.11e-204	657.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47NFW@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	pgtB	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA
TLS3_k127_1895718_2	1538644.KO02_07910	3.56e-158	507.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,1IQ7V@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
TLS3_k127_1895718_5	1408813.AYMG01000010_gene503	1.843e-47	177.0	COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,1ISPN@117747|Sphingobacteriia	976|Bacteroidetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
TLS3_k127_1895718_9	1121896.JMLU01000025_gene726	3.13e-09	69.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia,2NSMW@237|Flavobacterium	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
TLS3_k127_1895718_8	1122991.BAIZ01000022_gene1735	3.13e-09	69.0	COG0526@1|root,COG0526@2|Bacteria,4NS1W@976|Bacteroidetes,2G2XE@200643|Bacteroidia	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
TLS3_k127_1895718_4	927658.AJUM01000037_gene2378	1.205e-53	194.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,2FN8N@200643|Bacteroidia,3XJDB@558415|Marinilabiliaceae	976|Bacteroidetes	CO	Domain of unknown function (DUF4369)	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
TLS3_k127_1895718_0	1122621.ATZA01000002_gene1664	7.293e-215	674.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,1IPZR@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
TLS3_k127_1895718_3	926562.Oweho_3051	2.065e-60	215.0	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,1HXIU@117743|Flavobacteriia,2PAXH@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
TLS3_k127_1895718_6	1131812.JQMS01000001_gene1095	1.078e-18	85.0	2EH3B@1|root,33AVB@2|Bacteria,4NXP5@976|Bacteroidetes,1I6KT@117743|Flavobacteriia,2NWVF@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1905307_2	1443125.Z962_p0072	1.497e-17	85.0	28JCY@1|root,2Z97H@2|Bacteria,1USX6@1239|Firmicutes,2504H@186801|Clostridia,36RMW@31979|Clostridiaceae	186801|Clostridia	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
TLS3_k127_1905307_1	1124780.ANNU01000070_gene1103	1.83e-86	299.0	COG0732@1|root,COG0732@2|Bacteria,4NQZY@976|Bacteroidetes,47RQ2@768503|Cytophagia	976|Bacteroidetes	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
TLS3_k127_1905307_0	1191523.MROS_1293	4.111e-238	745.0	COG0286@1|root,COG0286@2|Bacteria	2|Bacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
TLS3_k127_1905307_3	1189620.AJXL01000024_gene3594	0.0004509	46.0	COG1476@1|root,COG1476@2|Bacteria,4NYE0@976|Bacteroidetes,1ID6A@117743|Flavobacteriia,2NXH4@237|Flavobacterium	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
TLS3_k127_1909854_0	865937.Gilli_1171	4.815e-119	387.0	COG2227@1|root,COG2227@2|Bacteria,4NF6D@976|Bacteroidetes,1HXVW@117743|Flavobacteriia	976|Bacteroidetes	H	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
TLS3_k127_1909854_1	1296415.JACC01000026_gene1785	1.124e-11	75.0	COG3577@1|root,COG3577@2|Bacteria,4NMGA@976|Bacteroidetes,1I091@117743|Flavobacteriia	976|Bacteroidetes	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
TLS3_k127_1914794_2	1122176.KB903535_gene1970	3.611e-49	197.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes	976|Bacteroidetes	E	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,MAM,TSP_3,fn3
TLS3_k127_1914794_3	984262.SGRA_0890	4.837e-12	79.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
TLS3_k127_1914794_0	1121285.AUFK01000013_gene2525	2.812e-142	461.0	COG1250@1|root,COG1250@2|Bacteria,4NF2W@976|Bacteroidetes,1HXCF@117743|Flavobacteriia,3ZNHN@59732|Chryseobacterium	976|Bacteroidetes	I	3-hydroxybutyryl-CoA dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
TLS3_k127_1914794_1	926549.KI421517_gene418	1.482e-61	227.0	COG3011@1|root,COG3011@2|Bacteria,4NIS5@976|Bacteroidetes,47JWB@768503|Cytophagia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_193948_0	452471.Aasi_1021	3.728e-79	276.0	COG3547@1|root,COG3547@2|Bacteria,4NKDC@976|Bacteroidetes,47NU4@768503|Cytophagia	976|Bacteroidetes	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
TLS3_k127_1945660_2	485918.Cpin_1833	5.337e-22	96.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1INSA@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
TLS3_k127_1945660_0	755732.Fluta_0944	4.236e-135	455.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,1HXI1@117743|Flavobacteriia,2PAM4@246874|Cryomorphaceae	976|Bacteroidetes	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
TLS3_k127_1945660_1	762903.Pedsa_3440	8.029e-39	156.0	COG0760@1|root,COG0760@2|Bacteria,4NG2P@976|Bacteroidetes,1IYQF@117747|Sphingobacteriia	976|Bacteroidetes	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
TLS3_k127_1945660_3	313606.M23134_06991	1.454e-11	72.0	2AAU0@1|root,3106Q@2|Bacteria,4NNSV@976|Bacteroidetes,47Q0I@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1961883_1	1392489.JPOL01000002_gene888	7.124e-188	596.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,1HWYI@117743|Flavobacteriia,2XI50@283735|Leeuwenhoekiella	976|Bacteroidetes	J	Uncharacterized protein family UPF0004	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
TLS3_k127_1961883_2	1131812.JQMS01000001_gene2069	2.904e-148	476.0	COG0798@1|root,COG0798@2|Bacteria,4NFG7@976|Bacteroidetes,1HWT1@117743|Flavobacteriia,2NSVM@237|Flavobacterium	976|Bacteroidetes	P	arsenical-resistance protein	acr3	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
TLS3_k127_1961883_7	153721.MYP_3344	2.04e-63	224.0	COG0394@1|root,COG0394@2|Bacteria,4NE8C@976|Bacteroidetes,47PXK@768503|Cytophagia	976|Bacteroidetes	T	PFAM Low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
TLS3_k127_1961883_6	1121887.AUDK01000018_gene3235	2.697e-65	226.0	2DBYA@1|root,2ZBU9@2|Bacteria,4NNGM@976|Bacteroidetes,1I19X@117743|Flavobacteriia,2NVW4@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1961883_8	1123248.KB893315_gene3111	5.289e-47	171.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,1IYKS@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
TLS3_k127_1961883_0	1122621.ATZA01000029_gene2778	3.541e-202	638.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,1IPIU@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
TLS3_k127_1961883_12	391596.PBAL39_07850	2.352e-22	102.0	28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,1ITP3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1961883_9	926562.Oweho_0373	3.071e-38	151.0	COG0431@1|root,COG0431@2|Bacteria,4NQV9@976|Bacteroidetes	976|Bacteroidetes	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
TLS3_k127_1961883_4	925409.KI911562_gene2946	3.59e-87	294.0	COG2220@1|root,COG2220@2|Bacteria,4NGD5@976|Bacteroidetes,1IRXP@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
TLS3_k127_1961883_3	755732.Fluta_3572	3.492e-119	389.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1HXYG@117743|Flavobacteriia,2PAED@246874|Cryomorphaceae	976|Bacteroidetes	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
TLS3_k127_1961883_5	927658.AJUM01000037_gene2193	2.426e-85	291.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,2FP81@200643|Bacteroidia,3XINV@558415|Marinilabiliaceae	976|Bacteroidetes	K	ParB-like nuclease domain	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
TLS3_k127_1961883_11	172045.KS04_01605	3.179e-30	125.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,1I19W@117743|Flavobacteriia,34QIB@308865|Elizabethkingia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
TLS3_k127_1961883_10	1112214.AHIS01000051_gene2424	6.907e-34	132.0	COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,2TYHX@28211|Alphaproteobacteria,2K0ZW@204457|Sphingomonadales	204457|Sphingomonadales	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.5.7	ko:K01502	ko00643,ko01120,map00643,map01120	-	R05358	RC01336	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
TLS3_k127_1971065_4	869213.JCM21142_93908	1.661e-06	55.0	2CICV@1|root,33IPP@2|Bacteria,4NXPC@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1971065_1	1279009.ADICEAN_03093	2.516e-48	177.0	COG0454@1|root,COG0456@2|Bacteria,4NNJS@976|Bacteroidetes,47PUS@768503|Cytophagia	976|Bacteroidetes	K	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
TLS3_k127_1971065_2	1380384.JADN01000004_gene2142	1.46e-30	128.0	COG3210@1|root,COG3210@2|Bacteria,4NW7P@976|Bacteroidetes,1I6RF@117743|Flavobacteriia	976|Bacteroidetes	MU	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1971065_0	929556.Solca_1338	7.745e-162	513.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,1IQAD@117747|Sphingobacteriia	976|Bacteroidetes	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
TLS3_k127_1973108_2	1121896.JMLU01000025_gene692	1.206e-24	102.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,1HYI9@117743|Flavobacteriia,2NSQU@237|Flavobacterium	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
TLS3_k127_1973108_0	1121870.AUAA01000045_gene2932	0.0	1047.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1HXMC@117743|Flavobacteriia,3HHRY@358033|Chryseobacterium	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
TLS3_k127_1973108_1	485918.Cpin_4708	6.902e-36	143.0	COG0791@1|root,COG0791@2|Bacteria,4NMT8@976|Bacteroidetes,1IRY7@117747|Sphingobacteriia	976|Bacteroidetes	M	Nlp p60 protein	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
TLS3_k127_1973108_4	760192.Halhy_6262	5.2e-09	65.0	2A78Y@1|root,30W5G@2|Bacteria,4NV8P@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1989624_1	929556.Solca_1438	1.825e-30	130.0	COG0457@1|root,COG0457@2|Bacteria,4NFHT@976|Bacteroidetes,1IRZE@117747|Sphingobacteriia	976|Bacteroidetes	S	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
TLS3_k127_1989624_2	1239962.C943_04201	3.339e-13	82.0	COG0457@1|root,COG0457@2|Bacteria,4NFHT@976|Bacteroidetes,47PQF@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
TLS3_k127_1989624_0	1121898.Q766_01620	2.59e-37	143.0	COG3384@1|root,COG3384@2|Bacteria,4NFGT@976|Bacteroidetes,1HX1P@117743|Flavobacteriia,2NS8H@237|Flavobacterium	976|Bacteroidetes	S	in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
TLS3_k127_1994394_10	1408433.JHXV01000015_gene1734	3.315e-07	56.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,4P03T@976|Bacteroidetes	976|Bacteroidetes	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
TLS3_k127_1994394_8	643867.Ftrac_1269	6.773e-17	87.0	COG0642@1|root,COG2205@2|Bacteria,4NX2D@976|Bacteroidetes,47T5N@768503|Cytophagia	976|Bacteroidetes	T	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
TLS3_k127_1994394_3	755732.Fluta_2314	3.444e-106	352.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1HWPM@117743|Flavobacteriia,2PA55@246874|Cryomorphaceae	976|Bacteroidetes	V	TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_1994394_5	1313301.AUGC01000003_gene2022	3.732e-67	241.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
TLS3_k127_1994394_0	926562.Oweho_1011	9.453e-174	567.0	COG0457@1|root,COG3303@1|root,COG0457@2|Bacteria,COG3303@2|Bacteria,4NDTY@976|Bacteroidetes,1HXS9@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1,TPR_2,TPR_8
TLS3_k127_1994394_6	1408473.JHXO01000006_gene1150	1.077e-47	176.0	COG1670@1|root,COG1670@2|Bacteria,4NQ8K@976|Bacteroidetes,2FMII@200643|Bacteroidia	976|Bacteroidetes	J	Acetyltransferase, gnat family	speG	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
TLS3_k127_1994394_4	313606.M23134_07654	5.309e-89	300.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,47KR3@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
TLS3_k127_1994394_1	385682.AFSL01000035_gene2906	1.149e-134	444.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,2FMUA@200643|Bacteroidia,3XJ0M@558415|Marinilabiliaceae	976|Bacteroidetes	O	Trypsin	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
TLS3_k127_1994394_7	1453500.AT05_00005	3.325e-36	142.0	COG0394@1|root,COG0394@2|Bacteria,4NNQZ@976|Bacteroidetes,1I1Z5@117743|Flavobacteriia	976|Bacteroidetes	T	Low molecular weight phosphotyrosine protein phosphatase	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
TLS3_k127_1994394_11	1123277.KB893180_gene2393	8.985e-06	56.0	2CKRP@1|root,2ZBUA@2|Bacteria,4NNCP@976|Bacteroidetes,47P90@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1994394_2	269798.CHU_1939	1.112e-116	377.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,47M06@768503|Cytophagia	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
TLS3_k127_2010817_3	1249975.JQLP01000003_gene162	1.096e-27	113.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes,1HWQR@117743|Flavobacteriia,2P6BG@244698|Gillisia	976|Bacteroidetes	M	NmrA-like family	wbpP	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
TLS3_k127_2010817_0	1124780.ANNU01000020_gene3278	0.0	1783.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,47KS7@768503|Cytophagia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
TLS3_k127_2010817_4	700598.Niako_0133	2.543e-22	101.0	2E373@1|root,32ZYW@2|Bacteria,4PQ2K@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2010817_1	1189620.AJXL01000044_gene1077	1.122e-70	249.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,1HZYF@117743|Flavobacteriia,2NTPA@237|Flavobacterium	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
TLS3_k127_2010817_2	755732.Fluta_2929	2.156e-28	117.0	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,1I2UP@117743|Flavobacteriia,2PB5G@246874|Cryomorphaceae	976|Bacteroidetes	K	helix_turn_helix, mercury resistance	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
TLS3_k127_2018193_5	945713.IALB_2756	5.078e-39	153.0	COG2515@1|root,COG2515@2|Bacteria	2|Bacteria	E	1-aminocyclopropane-1-carboxylate deaminase activity	acdS	-	3.5.99.7,4.4.1.15	ko:K01505,ko:K05396	ko00270,map00270	-	R00997,R01874	RC00382,RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
TLS3_k127_2018193_2	1249997.JHZW01000002_gene965	8.372e-143	466.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1HXPY@117743|Flavobacteriia,2PG5S@252356|Maribacter	976|Bacteroidetes	S	PSP1 C-terminal conserved region	fjo17	-	-	-	-	-	-	-	-	-	-	-	PSP1
TLS3_k127_2018193_7	471854.Dfer_4014	6.109e-29	124.0	2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,47PP1@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated lipoprotein, GldH	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	GldH_lipo
TLS3_k127_2018193_0	929556.Solca_3859	4.472e-155	496.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,1IQ84@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
TLS3_k127_2018193_6	755732.Fluta_1540	1.95e-32	131.0	COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,1I2V4@117743|Flavobacteriia,2PB44@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
TLS3_k127_2018193_1	700598.Niako_2068	1.235e-153	516.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IVBF@117747|Sphingobacteriia	2|Bacteria	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug
TLS3_k127_2018193_4	762903.Pedsa_2744	2.697e-65	228.0	COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,1IRC3@117747|Sphingobacteriia	976|Bacteroidetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
TLS3_k127_2018193_3	755732.Fluta_0300	1.83e-92	325.0	COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,1IKD1@117743|Flavobacteriia,2PAST@246874|Cryomorphaceae	976|Bacteroidetes	A	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
TLS3_k127_2018193_8	385682.AFSL01000095_gene806	6.754e-22	104.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,2FMKP@200643|Bacteroidia,3XJIU@558415|Marinilabiliaceae	976|Bacteroidetes	L	DNA-binding domain of DNA mismatch repair MUTS family	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
TLS3_k127_2019783_6	755732.Fluta_1682	1.247e-81	284.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4PI0A@976|Bacteroidetes,1IMVQ@117743|Flavobacteriia,2PBY2@246874|Cryomorphaceae	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_2019783_7	929556.Solca_0901	9.574e-69	244.0	COG0248@1|root,COG0248@2|Bacteria,4NH03@976|Bacteroidetes,1IQTS@117747|Sphingobacteriia	976|Bacteroidetes	FP	PFAM Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
TLS3_k127_2019783_1	1121904.ARBP01000002_gene7095	1.69e-165	528.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JKI@768503|Cytophagia	976|Bacteroidetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_2019783_4	153721.MYP_2132	1.361e-82	301.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4P1P3@976|Bacteroidetes,47THG@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
TLS3_k127_2019783_10	1519464.HY22_07530	4.609e-11	71.0	COG4886@1|root,COG4886@2|Bacteria,1FFPD@1090|Chlorobi	1090|Chlorobi	S	Leucine-rich repeats, typical (most populated) subfamily	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8
TLS3_k127_2019783_3	1249997.JHZW01000002_gene699	9.161e-90	305.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,1HXQ5@117743|Flavobacteriia,2PGM7@252356|Maribacter	976|Bacteroidetes	H	Riboflavin kinase	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
TLS3_k127_2019783_0	1453500.AT05_07745	2.373e-267	829.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1HWM2@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
TLS3_k127_2019783_8	1121957.ATVL01000008_gene4356	1.061e-19	90.0	COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,47S1U@768503|Cytophagia	976|Bacteroidetes	C	PFAM ATP synthase, Delta Epsilon chain, beta-sandwich domain	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
TLS3_k127_2019783_11	309807.SRU_p0003	0.0005823	53.0	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,4PHV3@976|Bacteroidetes,1FK10@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2019783_5	385682.AFSL01000060_gene1778	1.609e-82	286.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,2FKYG@200643|Bacteroidia,3XIQJ@558415|Marinilabiliaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_2019783_2	929556.Solca_3471	5.143e-137	449.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1IP0N@117747|Sphingobacteriia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
TLS3_k127_202000_1	1121870.AUAA01000012_gene1847	2.096e-58	206.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,1I1B5@117743|Flavobacteriia,3HHMK@358033|Chryseobacterium	976|Bacteroidetes	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
TLS3_k127_202000_0	869213.JCM21142_83126	1.045e-142	470.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,47JP7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
TLS3_k127_202000_4	755732.Fluta_2233	2.731e-15	81.0	COG2146@1|root,COG2146@2|Bacteria,4PFBM@976|Bacteroidetes,1ICTH@117743|Flavobacteriia,2PC3S@246874|Cryomorphaceae	976|Bacteroidetes	P	nitrite reductase [NAD(P)H] activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_202000_2	1150600.ADIARSV_2428	3.722e-55	199.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,1ISN4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated lipoprotein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_202000_3	1356852.N008_05970	1.3e-39	151.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,47QZT@768503|Cytophagia	976|Bacteroidetes	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
TLS3_k127_2034638_11	762903.Pedsa_0133	2.052e-31	125.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1IPWG@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
TLS3_k127_2034638_7	929556.Solca_2738	1.162e-130	426.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,1IPF4@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
TLS3_k127_2034638_6	714943.Mucpa_1521	5.431e-139	456.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1INTF@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_2034638_10	485917.Phep_3324	6.727e-38	153.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,1IX3I@117747|Sphingobacteriia	976|Bacteroidetes	D	Cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
TLS3_k127_2034638_3	509635.N824_17310	1.637e-167	538.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1IQJQ@117747|Sphingobacteriia	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
TLS3_k127_2034638_5	1408433.JHXV01000032_gene1131	8.258e-150	490.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1HWTE@117743|Flavobacteriia,2PADU@246874|Cryomorphaceae	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
TLS3_k127_2034638_0	1237149.C900_05297	0.0	1197.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,47MI0@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
TLS3_k127_2034638_1	1168034.FH5T_18860	0.0	1129.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,2FW95@200643|Bacteroidia	976|Bacteroidetes	L	DNA polymerase alpha chain like domain	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
TLS3_k127_2034638_8	1121870.AUAA01000005_gene1021	4.47e-69	237.0	COG1943@1|root,COG1943@2|Bacteria,4NQTF@976|Bacteroidetes,1I1DP@117743|Flavobacteriia,3HIAY@358033|Chryseobacterium	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
TLS3_k127_2034638_2	1121875.KB907550_gene731	5.901e-169	539.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,1HXFK@117743|Flavobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
TLS3_k127_2034638_4	1550091.JROE01000006_gene2472	1.402e-153	492.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,1IRZ6@117747|Sphingobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_2034638_13	1122176.KB903554_gene4005	6.314e-23	115.0	COG0384@1|root,COG3209@1|root,COG0384@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF,RHS_repeat
TLS3_k127_2034638_12	760192.Halhy_5055	8.653e-27	128.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2034638_9	485918.Cpin_1023	1.42e-55	199.0	COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,1INZJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	yafV	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
TLS3_k127_2039139_2	755732.Fluta_1284	3.748e-76	260.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
TLS3_k127_2039139_3	468059.AUHA01000006_gene3062	1.447e-41	156.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_2039139_4	1239962.C943_03447	6.024e-21	96.0	COG0477@1|root,COG2814@2|Bacteria,4NEN9@976|Bacteroidetes,47KR8@768503|Cytophagia	976|Bacteroidetes	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_2039139_0	269798.CHU_2865	2.403e-308	964.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,47KXK@768503|Cytophagia	976|Bacteroidetes	G	PFAM GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TLS3_k127_2039139_1	468059.AUHA01000002_gene936	3.276e-227	716.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1INRR@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yidK	-	-	-	-	-	-	-	-	-	-	-	SSF
TLS3_k127_2039139_5	1406840.Q763_16015	2.599e-11	66.0	2A9HF@1|root,30YPN@2|Bacteria,4PCJF@976|Bacteroidetes,1I9PE@117743|Flavobacteriia,2NXBX@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2043454_2	760192.Halhy_0926	4.607e-19	91.0	COG1575@1|root,COG1575@2|Bacteria,4PP13@976|Bacteroidetes,1J0WG@117747|Sphingobacteriia	976|Bacteroidetes	H	UbiA prenyltransferase family	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
TLS3_k127_2043454_0	760192.Halhy_0925	1.139e-75	267.0	COG3424@1|root,COG3424@2|Bacteria,4NDZU@976|Bacteroidetes,1IRE8@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM Chalcone and stilbene synthases, N-terminal domain	bcsA	-	-	-	-	-	-	-	-	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
TLS3_k127_2043454_1	471854.Dfer_2036	1.764e-20	94.0	COG0500@1|root,COG0500@2|Bacteria,4PM73@976|Bacteroidetes,47Y70@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
TLS3_k127_2122739_2	1123277.KB893232_gene1924	9.953e-16	90.0	COG3630@1|root,COG3630@2|Bacteria,4PKCP@976|Bacteroidetes,47Y7J@768503|Cytophagia	976|Bacteroidetes	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
TLS3_k127_2122739_0	755732.Fluta_2011	1.998e-259	813.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1HXZE@117743|Flavobacteriia,2PAAI@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
TLS3_k127_2122739_1	1313301.AUGC01000010_gene961	3.972e-27	112.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes	976|Bacteroidetes	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
TLS3_k127_2130377_2	1168034.FH5T_17375	2.744e-13	69.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,2FNGC@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
TLS3_k127_2130377_0	1168034.FH5T_17385	8.455e-202	635.0	COG0738@1|root,COG0738@2|Bacteria,4NEPI@976|Bacteroidetes,2FP0B@200643|Bacteroidia	976|Bacteroidetes	G	Transporter, major facilitator family protein	gluP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
TLS3_k127_2130377_1	1408473.JHXO01000012_gene383	5.038e-158	503.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,2FNXT@200643|Bacteroidia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
TLS3_k127_21825_0	1341181.FLJC2902T_01070	2.166e-241	755.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1HWTF@117743|Flavobacteriia,2NT1X@237|Flavobacterium	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
TLS3_k127_21825_2	1492737.FEM08_15380	1.863e-183	590.0	COG3104@1|root,COG3104@2|Bacteria,4NGWH@976|Bacteroidetes,1HY6B@117743|Flavobacteriia,2NUAF@237|Flavobacterium	976|Bacteroidetes	U	Amino acid transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
TLS3_k127_21825_4	313606.M23134_00128	8.461e-110	359.0	COG1028@1|root,COG1028@2|Bacteria,4NFTU@976|Bacteroidetes,47N2B@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	fabG3	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_21825_7	153721.MYP_2257	4.115e-44	164.0	COG2030@1|root,COG2030@2|Bacteria,4NPYH@976|Bacteroidetes,47PSF@768503|Cytophagia	976|Bacteroidetes	I	MaoC domain protein dehydratase	maoC	-	4.2.1.55	ko:K17865	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R03027	RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
TLS3_k127_21825_3	926549.KI421517_gene2587	3.963e-149	481.0	COG1092@1|root,COG1092@2|Bacteria,4NG9S@976|Bacteroidetes,47M5H@768503|Cytophagia	976|Bacteroidetes	J	SAM-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
TLS3_k127_21825_1	743722.Sph21_3379	1.641e-184	582.0	COG1060@1|root,COG1060@2|Bacteria,4NGDN@976|Bacteroidetes,1IPM7@117747|Sphingobacteriia	976|Bacteroidetes	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
TLS3_k127_21825_6	1408433.JHXV01000006_gene2768	2.936e-55	206.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1HY5S@117743|Flavobacteriia,2PAT9@246874|Cryomorphaceae	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
TLS3_k127_21825_8	1168034.FH5T_09290	4.466e-18	93.0	COG3637@1|root,COG3637@2|Bacteria,4NYY3@976|Bacteroidetes	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
TLS3_k127_21825_5	929556.Solca_1714	3.215e-64	223.0	COG0163@1|root,COG0163@2|Bacteria,4NIBD@976|Bacteroidetes,1INXX@117747|Sphingobacteriia	976|Bacteroidetes	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
TLS3_k127_2186107_0	886377.Murru_2406	5.091e-176	559.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
TLS3_k127_2186107_6	269798.CHU_3005	1.065e-50	198.0	2EF95@1|root,33921@2|Bacteria,4NXAE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2186107_3	926562.Oweho_3327	4.5e-120	396.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1HXN4@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
TLS3_k127_2186107_1	926562.Oweho_3326	7.934e-133	435.0	COG0577@1|root,COG0577@2|Bacteria,4NFUG@976|Bacteroidetes,1HZ09@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	macB_3	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_2186107_2	1408473.JHXO01000010_gene3697	2.998e-121	401.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,2FNZ2@200643|Bacteroidia	976|Bacteroidetes	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_2186107_4	1313421.JHBV01000006_gene298	7.663e-96	317.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1IQ8R@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_2186107_5	1121094.KB894661_gene2741	8.041e-69	243.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,2FMZ6@200643|Bacteroidia,4ANA5@815|Bacteroidaceae	976|Bacteroidetes	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
TLS3_k127_2187807_0	153721.MYP_4446	1.536e-234	728.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,47ME8@768503|Cytophagia	976|Bacteroidetes	EF	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
TLS3_k127_2187807_3	1453505.JASY01000001_gene3732	1.925e-07	57.0	COG2010@1|root,COG2010@2|Bacteria,4NXZT@976|Bacteroidetes,1I673@117743|Flavobacteriia,2NX4B@237|Flavobacterium	976|Bacteroidetes	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHC
TLS3_k127_2187807_2	755732.Fluta_2340	1.072e-12	81.0	COG3291@1|root,COG4935@1|root,COG5492@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,COG5492@2|Bacteria,4NDZQ@976|Bacteroidetes	976|Bacteroidetes	H	Gliding motility-associated C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,Ig_3
TLS3_k127_2187807_1	755732.Fluta_2090	1.012e-21	105.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_2189838_2	929556.Solca_0931	7.585e-117	399.0	COG1572@1|root,COG1572@2|Bacteria,4PM6M@976|Bacteroidetes,1J0JA@117747|Sphingobacteriia	976|Bacteroidetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB
TLS3_k127_2189838_3	860228.Ccan_14740	1.573e-34	145.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,1I21X@117743|Flavobacteriia,1ES0Q@1016|Capnocytophaga	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_2189838_0	1185876.BN8_06099	9.702e-212	683.0	COG4206@1|root,COG4206@2|Bacteria,4PM93@976|Bacteroidetes,47YB2@768503|Cytophagia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_2189838_1	1120965.AUBV01000006_gene2207	1.271e-176	560.0	COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,47K0A@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
TLS3_k127_2189838_4	649349.Lbys_2046	1.03e-30	122.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,47JDH@768503|Cytophagia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
TLS3_k127_2212770_1	143224.JQMD01000002_gene1339	6.705e-09	57.0	COG0610@1|root,COG3206@1|root,COG0610@2|Bacteria,COG3206@2|Bacteria,4NFJ8@976|Bacteroidetes,1HXHQ@117743|Flavobacteriia	976|Bacteroidetes	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
TLS3_k127_2212770_0	1237149.C900_01709	5.32e-108	361.0	COG5433@1|root,COG5433@2|Bacteria,4NHJC@976|Bacteroidetes,47X71@768503|Cytophagia	976|Bacteroidetes	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
TLS3_k127_2215559_2	317619.ANKN01000188_gene3671	2.588e-180	575.0	COG1282@1|root,COG1282@2|Bacteria,1G2AX@1117|Cyanobacteria,1MKJR@1212|Prochloraceae	1117|Cyanobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
TLS3_k127_2215559_1	118163.Ple7327_2936	2.021e-184	589.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,3VIVK@52604|Pleurocapsales	1117|Cyanobacteria	C	PFAM Alanine dehydrogenase PNT, C-terminal domain	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
TLS3_k127_2215559_3	1279009.ADICEAN_01004	2.219e-106	348.0	COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,47MGG@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
TLS3_k127_2215559_7	641524.ADICYQ_4358	1.104e-08	61.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47YCR@768503|Cytophagia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_2215559_6	926559.JoomaDRAFT_1496	8.139e-13	75.0	COG2849@1|root,COG2849@2|Bacteria,4NS8U@976|Bacteroidetes,1I41J@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_2215559_0	1121904.ARBP01000002_gene6918	1.693e-205	657.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,47UE3@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter C-terminal domain	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
TLS3_k127_2215559_4	1408813.AYMG01000030_gene689	1.916e-104	344.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1IP0Y@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC transporter	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
TLS3_k127_2215559_5	1168289.AJKI01000044_gene106	5.858e-40	151.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,2FNVR@200643|Bacteroidia,3XIZS@558415|Marinilabiliaceae	976|Bacteroidetes	Q	Permease MlaE	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
TLS3_k127_2235914_8	655815.ZPR_2029	2.41e-21	98.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1HWWR@117743|Flavobacteriia	976|Bacteroidetes	V	abc transporter (atp-binding protein)	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
TLS3_k127_2235914_6	153721.MYP_4425	8.978e-30	122.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,47Q35@768503|Cytophagia	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
TLS3_k127_2235914_3	1168034.FH5T_07775	4.255e-74	264.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,2FNHB@200643|Bacteroidia	976|Bacteroidetes	M	Efflux ABC transporter, permease protein	lolE	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
TLS3_k127_2235914_7	1121904.ARBP01000001_gene5794	6.605e-22	99.0	COG2146@1|root,COG2146@2|Bacteria,4NVFP@976|Bacteroidetes,47S4K@768503|Cytophagia	976|Bacteroidetes	P	Rieske [2Fe-2S] domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
TLS3_k127_2235914_2	762903.Pedsa_0258	1.714e-82	281.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1IP8Q@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
TLS3_k127_2235914_5	927658.AJUM01000037_gene2194	3.379e-30	126.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,2FTY0@200643|Bacteroidia,3XK1I@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2235914_0	237368.SCABRO_01436	1.284e-111	375.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
TLS3_k127_2235914_1	945713.IALB_2228	2.307e-103	356.0	COG0471@1|root,COG0471@2|Bacteria	2|Bacteria	P	metal ion transport	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
TLS3_k127_2235914_4	694427.Palpr_1980	2.46e-54	195.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,2FKZC@200643|Bacteroidia,22W92@171551|Porphyromonadaceae	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
TLS3_k127_2285550_1	1178825.ALIH01000012_gene1844	1.277e-08	67.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2300482_1	331678.Cphamn1_2408	1.739e-122	409.0	COG5421@1|root,COG5421@2|Bacteria,1FF95@1090|Chlorobi	1090|Chlorobi	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
TLS3_k127_2300482_0	679937.Bcop_0607	8.408e-126	410.0	COG3464@1|root,COG3464@2|Bacteria,4NFK7@976|Bacteroidetes,2FPDJ@200643|Bacteroidia,4AK8H@815|Bacteroidaceae	976|Bacteroidetes	L	COG COG3464 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3
TLS3_k127_2300482_2	1492737.FEM08_08810	4.388e-21	92.0	COG1484@1|root,COG1484@2|Bacteria,4NFE0@976|Bacteroidetes,1HYB4@117743|Flavobacteriia,2NUR4@237|Flavobacterium	976|Bacteroidetes	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
TLS3_k127_2308511_0	1124780.ANNU01000002_gene1509	1.312e-173	587.0	COG0308@1|root,COG0308@2|Bacteria,4NF3R@976|Bacteroidetes,47N7W@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4,ABC2_membrane_5,Peptidase_M1
TLS3_k127_2308511_2	865937.Gilli_1389	4.7e-05	50.0	COG1680@1|root,COG1680@2|Bacteria,4P2WS@976|Bacteroidetes,1I8N9@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_2308511_1	1406840.Q763_12015	1.7e-56	204.0	COG3863@1|root,COG3863@2|Bacteria,4NNFN@976|Bacteroidetes,1IKHV@117743|Flavobacteriia,2P0HV@237|Flavobacterium	976|Bacteroidetes	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
TLS3_k127_2308511_3	1189612.A33Q_1323	0.0005125	49.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47MW3@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2
TLS3_k127_2315304_3	926562.Oweho_1917	5.629e-55	198.0	COG0526@1|root,COG0526@2|Bacteria,4NNHX@976|Bacteroidetes,1I33N@117743|Flavobacteriia,2PAUY@246874|Cryomorphaceae	976|Bacteroidetes	CO	AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
TLS3_k127_2315304_2	1453500.AT05_00420	4.57e-127	426.0	2CIBF@1|root,2Z85N@2|Bacteria,4NF0J@976|Bacteroidetes,1HYX2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2315304_4	1453500.AT05_05495	9.105e-33	138.0	2DMY7@1|root,32UCK@2|Bacteria,4NSK3@976|Bacteroidetes	976|Bacteroidetes	S	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Omp28
TLS3_k127_2315304_1	1202532.FF52_20345	1.04e-137	441.0	COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,1HXEE@117743|Flavobacteriia,2NUBV@237|Flavobacterium	976|Bacteroidetes	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
TLS3_k127_2315304_7	1408433.JHXV01000010_gene507	2.735e-12	73.0	2A3J1@1|root,30S22@2|Bacteria,4PCED@976|Bacteroidetes,1ICTW@117743|Flavobacteriia,2PC5J@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2315304_5	927658.AJUM01000047_gene2831	6.232e-27	121.0	29N3N@1|root,32D2M@2|Bacteria,4NRTM@976|Bacteroidetes,2G223@200643|Bacteroidia,3XJ24@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2315304_0	1358423.N180_17070	6.322e-204	640.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,1IQ0Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
TLS3_k127_2315304_6	755732.Fluta_2090	2.992e-22	107.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_2321235_0	755732.Fluta_3212	6.065e-57	227.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Laminin_G_3,PKD
TLS3_k127_2321235_2	531844.FIC_01200	7.393e-23	116.0	COG1345@1|root,COG3209@1|root,COG1345@2|Bacteria,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,4074H@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,SprB
TLS3_k127_2321235_1	929562.Emtol_4095	7.202e-23	98.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,47MA4@768503|Cytophagia	976|Bacteroidetes	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
TLS3_k127_2324075_1	1453500.AT05_08795	7.24e-132	457.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2324075_2	1122176.KB903565_gene3246	4.356e-84	291.0	COG2067@1|root,COG2067@2|Bacteria,4NWE8@976|Bacteroidetes,1IYUI@117747|Sphingobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_2324075_4	1122226.AUHX01000007_gene2683	2.656e-61	215.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,1I18I@117743|Flavobacteriia	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
TLS3_k127_2324075_5	1121285.AUFK01000020_gene3258	3.244e-42	159.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,1I1YY@117743|Flavobacteriia,3ZRRB@59732|Chryseobacterium	976|Bacteroidetes	FG	HIT family hydrolase	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
TLS3_k127_2324075_0	1515613.HQ37_08285	9.729e-255	793.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,2FMM2@200643|Bacteroidia,22WCA@171551|Porphyromonadaceae	976|Bacteroidetes	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
TLS3_k127_2324075_3	886379.AEWI01000026_gene428	3.173e-62	220.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,2FN90@200643|Bacteroidia,3XJUJ@558415|Marinilabiliaceae	976|Bacteroidetes	H	Pantoate-beta-alanine ligase	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
TLS3_k127_2345476_0	925409.KI911562_gene193	9.456e-64	220.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,1IP1Y@117747|Sphingobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
TLS3_k127_2345476_1	761193.Runsl_3687	3.256e-40	165.0	COG0204@1|root,COG0204@2|Bacteria,4NK8Z@976|Bacteroidetes,47NT5@768503|Cytophagia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TLS3_k127_2345476_2	755732.Fluta_1678	1.051e-07	57.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1HXT1@117743|Flavobacteriia,2PAQC@246874|Cryomorphaceae	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
TLS3_k127_2358748_9	1250232.JQNJ01000001_gene167	2.693e-09	62.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1HXHP@117743|Flavobacteriia	976|Bacteroidetes	NU	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
TLS3_k127_2358748_0	929556.Solca_3491	1.264e-206	646.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1IPN4@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_2358748_5	1408473.JHXO01000009_gene3369	9.37e-104	348.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,2FQSQ@200643|Bacteroidia	976|Bacteroidetes	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
TLS3_k127_2358748_10	1121897.AUGO01000014_gene3454	6.471e-07	61.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,4NI4A@976|Bacteroidetes,1I0P7@117743|Flavobacteriia	976|Bacteroidetes	O	Fibronectin, type III domain	-	-	-	-	-	-	-	-	-	-	-	-	Cleaved_Adhesin,MAM,PKD,fn3
TLS3_k127_2358748_11	1484460.JSWG01000015_gene1140	0.0003104	53.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_10,CBM_5_12_2,CBM_6,Glyco_hydro_16,RicinB_lectin_2,Ricin_B_lectin
TLS3_k127_2358748_2	755732.Fluta_2594	3.748e-157	505.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1HWYE@117743|Flavobacteriia,2PAIE@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Alanine dehydrogenase PNT, C-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
TLS3_k127_2358748_3	616991.JPOO01000001_gene3306	3.042e-135	436.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,1HWU7@117743|Flavobacteriia,23FN0@178469|Arenibacter	976|Bacteroidetes	I	Acyl transferase domain	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
TLS3_k127_2358748_1	929556.Solca_1245	1.627e-173	550.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,1IR3X@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
TLS3_k127_2358748_7	1408433.JHXV01000001_gene946	6.805e-38	152.0	COG2849@1|root,COG2849@2|Bacteria,4NP2Z@976|Bacteroidetes,1I22V@117743|Flavobacteriia,2PB39@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_2358748_8	1121943.KB899997_gene1719	1.765e-23	105.0	COG0645@1|root,COG0645@2|Bacteria,1N1S8@1224|Proteobacteria,1SEDC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
TLS3_k127_2358748_6	755732.Fluta_4050	4.175e-83	301.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
TLS3_k127_2358748_4	1123008.KB905698_gene3387	4.999e-112	366.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes,2FMUU@200643|Bacteroidia,22WFD@171551|Porphyromonadaceae	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	wbpP	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
TLS3_k127_2365642_0	1408473.JHXO01000010_gene3748	5.85e-77	267.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,2FMKE@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
TLS3_k127_2365642_2	762903.Pedsa_2251	2.364e-54	192.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1ISZS@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
TLS3_k127_2365642_1	1122225.AULQ01000006_gene982	4.381e-73	251.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1HYUM@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
TLS3_k127_2373766_2	391587.KAOT1_19557	2.042e-34	137.0	COG1708@1|root,COG1708@2|Bacteria,4NPRU@976|Bacteroidetes,1I105@117743|Flavobacteriia	976|Bacteroidetes	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
TLS3_k127_2373766_0	1313421.JHBV01000029_gene1972	1.565e-168	543.0	COG1032@1|root,COG1032@2|Bacteria,4NETM@976|Bacteroidetes,1IQPV@117747|Sphingobacteriia	976|Bacteroidetes	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
TLS3_k127_2373766_1	945713.IALB_2765	1.371e-50	190.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	MetW,Methyltransf_11,Methyltransf_25,Methyltransf_31
TLS3_k127_2374390_9	1120951.AUBG01000009_gene3001	1.799e-05	57.0	COG3391@1|root,COG3391@2|Bacteria,4NT0U@976|Bacteroidetes,1I43W@117743|Flavobacteriia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2374390_2	762903.Pedsa_3848	7.793e-188	591.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,1IPRN@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
TLS3_k127_2374390_4	1454007.JAUG01000033_gene3745	1.133e-142	464.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1IQ3C@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
TLS3_k127_2374390_8	435591.BDI_0195	3.443e-15	79.0	COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,2FSK4@200643|Bacteroidia,22YIT@171551|Porphyromonadaceae	976|Bacteroidetes	U	Preprotein translocase	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
TLS3_k127_2374390_7	755732.Fluta_2281	5.516e-22	107.0	2ABIA@1|root,310ZH@2|Bacteria,4PFMS@976|Bacteroidetes,1ICAQ@117743|Flavobacteriia,2PB8S@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2374390_6	468059.AUHA01000002_gene481	2.928e-39	151.0	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,1ISX2@117747|Sphingobacteriia	976|Bacteroidetes	S	Lipopolysaccharide-assembly	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
TLS3_k127_2374390_3	926559.JoomaDRAFT_1749	3.515e-153	494.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,1HXHS@117743|Flavobacteriia	976|Bacteroidetes	K	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
TLS3_k127_2374390_1	525373.HMPREF0766_10594	1.496e-206	653.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1IPSP@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
TLS3_k127_2374390_0	1358423.N180_20420	0.0	1111.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,4NF9S@976|Bacteroidetes,1IPJD@117747|Sphingobacteriia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
TLS3_k127_2374390_5	421072.IO89_06920	7.322e-82	276.0	COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,1HYFU@117743|Flavobacteriia,3HHUR@358033|Chryseobacterium	976|Bacteroidetes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
TLS3_k127_2385134_2	760192.Halhy_6369	2.741e-71	251.0	COG4447@1|root,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes	976|Bacteroidetes	O	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
TLS3_k127_2385134_1	553178.CAPGI0001_1720	5.273e-118	381.0	COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,1HXUY@117743|Flavobacteriia,1ER5Q@1016|Capnocytophaga	976|Bacteroidetes	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
TLS3_k127_2385134_0	755732.Fluta_0503	4.853e-239	760.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,1HZTJ@117743|Flavobacteriia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
TLS3_k127_2386784_3	1122605.KB893625_gene2118	2.774e-35	139.0	COG0457@1|root,COG0457@2|Bacteria,4NDTY@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_19,TPR_8
TLS3_k127_2386784_0	1239962.C943_02423	0.0	1222.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47MT5@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
TLS3_k127_2386784_1	530564.Psta_1821	0.0	1011.0	COG3119@1|root,COG3119@2|Bacteria,2IX0Y@203682|Planctomycetes	203682|Planctomycetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
TLS3_k127_2386784_2	1121904.ARBP01000013_gene393	9.822e-88	306.0	COG4784@1|root,COG4784@2|Bacteria,4PM59@976|Bacteroidetes,47MK2@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TLS3_k127_2388565_1	1121897.AUGO01000007_gene443	5.099e-63	217.0	2CUMY@1|root,32SVM@2|Bacteria,4NTF0@976|Bacteroidetes,1I3KN@117743|Flavobacteriia,2NZXB@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_2388565_0	869213.JCM21142_41599	2.904e-162	516.0	COG0535@1|root,COG0535@2|Bacteria,4NHXT@976|Bacteroidetes	976|Bacteroidetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
TLS3_k127_2399973_0	1454007.JAUG01000003_gene3068	0.0	1187.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1IQJH@117747|Sphingobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
TLS3_k127_2399973_1	1150600.ADIARSV_2467	2.422e-267	852.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1IPY5@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_2399973_2	709991.Odosp_0710	2.145e-06	55.0	COG4783@1|root,COG4783@2|Bacteria,4P1TE@976|Bacteroidetes,2G0E9@200643|Bacteroidia,23266@171551|Porphyromonadaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
TLS3_k127_2404480_0	755732.Fluta_3104	2.079e-233	760.0	COG3291@1|root,COG3291@2|Bacteria,4PI0I@976|Bacteroidetes,1I5WG@117743|Flavobacteriia,2PBH4@246874|Cryomorphaceae	2|Bacteria	S	C-terminal domain of CHU protein family	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_2408061_2	1121930.AQXG01000004_gene2890	2.39e-38	161.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NHSC@976|Bacteroidetes,1J066@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Reg_prop,SpoIIE,Y_Y_Y
TLS3_k127_2408061_1	1122225.AULQ01000011_gene128	2.221e-61	215.0	COG1443@1|root,COG1443@2|Bacteria,4NFJV@976|Bacteroidetes,1HXIQ@117743|Flavobacteriia	976|Bacteroidetes	I	Isopentenyl-diphosphate delta-isomerase	idi	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
TLS3_k127_2408061_0	1453500.AT05_04645	8.576e-116	398.0	COG2885@1|root,COG3063@1|root,COG2885@2|Bacteria,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,OmpA,PD40,TPR_16,TPR_19,TPR_4,TPR_8
TLS3_k127_2430511_2	929556.Solca_2465	3.656e-53	192.0	COG2081@1|root,COG2081@2|Bacteria,4NFQ9@976|Bacteroidetes,1INVK@117747|Sphingobacteriia	976|Bacteroidetes	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
TLS3_k127_2430511_0	1313421.JHBV01000047_gene144	6.159e-230	722.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1INYZ@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.32,1.2.1.85	ko:K10217	ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220	M00038,M00569	R02762,R03889,R05353	RC00218,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_2430511_5	1382306.JNIM01000001_gene360	9.686e-11	72.0	COG0484@1|root,COG0484@2|Bacteria,2G5NV@200795|Chloroflexi	200795|Chloroflexi	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
TLS3_k127_2430511_1	643867.Ftrac_1575	1.373e-59	208.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,47PQ6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
TLS3_k127_2430511_3	391596.PBAL39_24530	8.333e-36	139.0	COG0633@1|root,COG0633@2|Bacteria,4NQ4P@976|Bacteroidetes,1IXWV@117747|Sphingobacteriia	976|Bacteroidetes	C	2Fe-2S iron-sulfur cluster binding domain	thcC	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
TLS3_k127_2430511_4	1249975.JQLP01000005_gene1701	1.846e-32	135.0	2CCJ7@1|root,2ZA02@2|Bacteria,4NGH8@976|Bacteroidetes,1HXKM@117743|Flavobacteriia,2P6G3@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2436602_1	1122621.ATZA01000025_gene2386	1.005e-46	173.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1IQ4H@117747|Sphingobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
TLS3_k127_2436602_0	926549.KI421517_gene8	7.077e-310	977.0	COG0612@1|root,COG0612@2|Bacteria,4NDXM@976|Bacteroidetes,47JU2@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_2436602_2	762903.Pedsa_2295	7.268e-19	96.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1IQ35@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
TLS3_k127_2454530_3	1123057.P872_10555	1.465e-62	217.0	COG0664@1|root,COG0664@2|Bacteria,4NSMK@976|Bacteroidetes,47PHC@768503|Cytophagia	976|Bacteroidetes	T	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
TLS3_k127_2454530_0	700598.Niako_3172	8.195e-193	608.0	COG0477@1|root,COG2814@2|Bacteria,4NEN9@976|Bacteroidetes,1IR8C@117747|Sphingobacteriia	976|Bacteroidetes	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_2454530_2	1472716.KBK24_0127670	2.506e-68	238.0	COG0110@1|root,COG0110@2|Bacteria,1MZ7U@1224|Proteobacteria,2VVVZ@28216|Betaproteobacteria,1K3EF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	ko:K13006,ko:K19429	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
TLS3_k127_2454530_1	1086011.HJ01_03461	2.369e-173	558.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,4PKV1@976|Bacteroidetes,1IKKI@117743|Flavobacteriia,2P0QX@237|Flavobacterium	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_2454530_5	1121007.AUML01000009_gene3794	4.258e-14	81.0	2DRHS@1|root,33BTF@2|Bacteria,4NXHD@976|Bacteroidetes,1II4K@117743|Flavobacteriia,2YKV8@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2454530_4	755732.Fluta_3795	9.62e-17	80.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia,2PBRQ@246874|Cryomorphaceae	976|Bacteroidetes	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
TLS3_k127_2477809_2	926562.Oweho_0192	3.155e-67	235.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
TLS3_k127_2477809_6	1122621.ATZA01000054_gene60	5.532e-31	125.0	COG2332@1|root,COG2332@2|Bacteria,4NN85@976|Bacteroidetes,1IT63@117747|Sphingobacteriia	976|Bacteroidetes	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
TLS3_k127_2477809_8	1356852.N008_05560	6.247e-07	53.0	2BZQ6@1|root,339SI@2|Bacteria,4NXJG@976|Bacteroidetes,47SN2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2477809_1	1453500.AT05_01005	5.071e-82	278.0	COG0755@1|root,COG0755@2|Bacteria,4NFUS@976|Bacteroidetes	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
TLS3_k127_2477809_4	471854.Dfer_5084	3.775e-47	177.0	COG2386@1|root,COG2386@2|Bacteria,4NFQV@976|Bacteroidetes,47K0P@768503|Cytophagia	976|Bacteroidetes	O	ABC-type transport system involved in cytochrome c biogenesis permease component	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
TLS3_k127_2477809_7	755732.Fluta_2092	3.167e-22	113.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1I0R3@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
TLS3_k127_2477809_3	1123037.AUDE01000041_gene1235	4.536e-59	229.0	COG0823@1|root,COG3291@1|root,COG0823@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,IgGFc_binding,PKD,SprB
TLS3_k127_2477809_0	1336803.PHEL49_0218	1.2e-188	598.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,1HXGE@117743|Flavobacteriia,3VVSE@52959|Polaribacter	976|Bacteroidetes	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
TLS3_k127_2477809_5	1408433.JHXV01000004_gene3393	4.086e-47	185.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NUDC@976|Bacteroidetes,1I7JN@117743|Flavobacteriia,2PA5J@246874|Cryomorphaceae	976|Bacteroidetes	Q	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_2480373_1	755732.Fluta_2032	6.058e-70	256.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	srrB	-	-	-	-	-	-	-	-	-	-	-	CBS,HAMP,SpoIIE,dCache_1
TLS3_k127_2480373_0	929556.Solca_4126	4.637e-276	856.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
TLS3_k127_2480373_2	1124780.ANNU01000023_gene3188	6.34e-42	155.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,47QCW@768503|Cytophagia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
TLS3_k127_2505921_1	1406840.Q763_15940	5.131e-122	397.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1HXD2@117743|Flavobacteriia,2NTGZ@237|Flavobacterium	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
TLS3_k127_2505921_0	1121904.ARBP01000003_gene6407	3.769e-131	441.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
TLS3_k127_2507970_0	984262.SGRA_2800	5.166e-173	558.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,4NFTN@976|Bacteroidetes,1INM2@117747|Sphingobacteriia	976|Bacteroidetes	CE	PFAM Peptidase M1 membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
TLS3_k127_2507970_1	1121373.KB903620_gene2164	1.141e-31	126.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
TLS3_k127_2512124_13	762903.Pedsa_2033	3.578e-53	192.0	COG0344@1|root,COG0344@2|Bacteria,4NMU3@976|Bacteroidetes,1IPFE@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
TLS3_k127_2512124_5	926562.Oweho_3400	6.643e-92	317.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,1HY3Q@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
TLS3_k127_2512124_10	1121373.KB903666_gene1270	3.075e-72	247.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,47PA6@768503|Cytophagia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
TLS3_k127_2512124_18	1123276.KB893263_gene4633	9.725e-16	88.0	COG0392@1|root,COG0392@2|Bacteria,4NI8Y@976|Bacteroidetes,47NMA@768503|Cytophagia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
TLS3_k127_2512124_15	1353276.JADR01000007_gene1362	2.508e-41	166.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,1HXPD@117743|Flavobacteriia	976|Bacteroidetes	M	probably involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_2512124_2	929556.Solca_3225	8.609e-129	423.0	COG1173@1|root,COG1173@2|Bacteria,4NGTQ@976|Bacteroidetes,1IQI5@117747|Sphingobacteriia	976|Bacteroidetes	EP	PFAM Binding-protein-dependent transport system inner membrane component	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
TLS3_k127_2512124_6	762903.Pedsa_0777	9.252e-88	297.0	COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,1IRFD@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
TLS3_k127_2512124_16	1123057.P872_24670	1.25e-22	101.0	COG0694@1|root,COG0694@2|Bacteria,4NSHJ@976|Bacteroidetes,47RA0@768503|Cytophagia	976|Bacteroidetes	O	NifU domain protein	nfuA	-	-	-	-	-	-	-	-	-	-	-	NifU
TLS3_k127_2512124_1	1279009.ADICEAN_00193	1.788e-147	472.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,47KQ7@768503|Cytophagia	976|Bacteroidetes	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
TLS3_k127_2512124_7	1250005.PHEL85_1831	5.999e-82	278.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,1HXCG@117743|Flavobacteriia,3VV5P@52959|Polaribacter	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
TLS3_k127_2512124_12	1408433.JHXV01000007_gene2958	8.345e-57	205.0	COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,1HXW4@117743|Flavobacteriia,2PAZY@246874|Cryomorphaceae	976|Bacteroidetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
TLS3_k127_2512124_4	700598.Niako_0353	3.468e-105	346.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,1IQ0U@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
TLS3_k127_2512124_9	402612.FP2088	3.056e-79	274.0	COG0596@1|root,COG0596@2|Bacteria,4NDZI@976|Bacteroidetes,1HXF6@117743|Flavobacteriia,2NSWX@237|Flavobacterium	976|Bacteroidetes	S	Alpha beta hydrolase	ybfF	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_2512124_14	485918.Cpin_0647	2.14e-45	171.0	COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,1IS3Y@117747|Sphingobacteriia	976|Bacteroidetes	S	HAD-superfamily hydrolase subfamily IA, variant 3	yihX	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
TLS3_k127_2512124_11	1121373.KB903648_gene3337	2.509e-65	257.0	COG2885@1|root,COG3291@1|root,COG3405@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,COG3405@2|Bacteria,4NFM6@976|Bacteroidetes,47QNX@768503|Cytophagia	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_2512124_8	869213.JCM21142_83275	6.326e-81	308.0	COG1345@1|root,COG1520@1|root,COG3291@1|root,COG1345@2|Bacteria,COG1520@2|Bacteria,COG3291@2|Bacteria,4NJRF@976|Bacteroidetes,47PMY@768503|Cytophagia	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_2512124_17	1189612.A33Q_4154	2.361e-18	102.0	COG3291@1|root,COG3291@2|Bacteria,4NNVK@976|Bacteroidetes,47XA2@768503|Cytophagia	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
TLS3_k127_2512124_3	929562.Emtol_2588	3.707e-125	411.0	COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,47JRK@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
TLS3_k127_2512124_0	929562.Emtol_2590	9.944e-265	833.0	COG1538@1|root,COG3696@1|root,COG1538@2|Bacteria,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,47JC4@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
TLS3_k127_258664_5	156578.ATW7_17813	1.674e-76	260.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	peptidase, M13	pepO	-	3.4.24.71	ko:K01415,ko:K07386	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
TLS3_k127_258664_3	1313421.JHBV01000023_gene5122	1.786e-89	312.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1IP77@117747|Sphingobacteriia	976|Bacteroidetes	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
TLS3_k127_258664_0	388413.ALPR1_04563	1.909e-190	603.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,47JPG@768503|Cytophagia	976|Bacteroidetes	F	TIGRFAM dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
TLS3_k127_258664_6	755732.Fluta_3212	8.282e-18	93.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Laminin_G_3,PKD
TLS3_k127_258664_4	643867.Ftrac_2976	1.18e-83	284.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,47JXK@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
TLS3_k127_258664_2	929556.Solca_2092	3.065e-109	363.0	COG2870@1|root,COG2870@2|Bacteria,4NHUV@976|Bacteroidetes,1IQQ3@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
TLS3_k127_258664_1	468059.AUHA01000003_gene1988	3.051e-109	360.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,1INY0@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_2597960_19	1121374.KB891575_gene1031	9.339e-11	69.0	298PG@1|root,2ZVTY@2|Bacteria,1RIKV@1224|Proteobacteria,1SQW0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2597960_12	1173020.Cha6605_5220	1.927e-51	193.0	COG0382@1|root,COG0382@2|Bacteria,1G1UG@1117|Cyanobacteria	1117|Cyanobacteria	H	PFAM UbiA prenyltransferase	-	GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009987,GO:0010189,GO:0018130,GO:0042360,GO:0042362,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617	2.5.1.115,2.5.1.116	ko:K09833	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07500,R10708	RC01840,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iJN678.slr1736	UbiA
TLS3_k127_2597960_6	1120966.AUBU01000002_gene2049	1.072e-83	290.0	COG0147@1|root,COG0147@2|Bacteria,4NECR@976|Bacteroidetes,47K5D@768503|Cytophagia	976|Bacteroidetes	EH	Anthranilate para-aminobenzoate synthase component I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
TLS3_k127_2597960_7	1229487.AMYW01000021_gene1750	3.613e-77	263.0	COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes,1HYH0@117743|Flavobacteriia,2NTGU@237|Flavobacterium	976|Bacteroidetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
TLS3_k127_2597960_4	1123248.KB893337_gene2591	8.64e-108	362.0	COG2234@1|root,COG2234@2|Bacteria,4NGPJ@976|Bacteroidetes,1IRMB@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
TLS3_k127_2597960_21	1185876.BN8_05832	2.086e-05	53.0	COG3827@1|root,COG3827@2|Bacteria,4PMMQ@976|Bacteroidetes,47Y53@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2597960_9	742817.HMPREF9449_01584	1.314e-73	252.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,2FN2K@200643|Bacteroidia,22W1X@171551|Porphyromonadaceae	976|Bacteroidetes	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
TLS3_k127_2597960_1	762903.Pedsa_0984	4.091e-242	772.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,1IP9R@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
TLS3_k127_2597960_17	755732.Fluta_3212	2.668e-13	83.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Laminin_G_3,PKD
TLS3_k127_2597960_11	1341181.FLJC2902T_24380	9.921e-57	222.0	COG2356@1|root,COG3291@1|root,COG3391@1|root,COG4733@1|root,COG4886@1|root,COG2356@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,4NJHV@976|Bacteroidetes,1IMXD@117743|Flavobacteriia,2NV4Y@237|Flavobacterium	976|Bacteroidetes	O	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
TLS3_k127_2597960_2	1121887.AUDK01000011_gene136	4.516e-130	427.0	COG0025@1|root,COG0025@2|Bacteria,4NK07@976|Bacteroidetes,1HWM6@117743|Flavobacteriia,2NTFF@237|Flavobacterium	976|Bacteroidetes	P	Pfam Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
TLS3_k127_2597960_20	1408433.JHXV01000005_gene2408	6.254e-06	59.0	COG1404@1|root,COG2706@1|root,COG3291@1|root,COG3292@1|root,COG1404@2|Bacteria,COG2706@2|Bacteria,COG3291@2|Bacteria,COG3292@2|Bacteria,4PMMT@976|Bacteroidetes,1IJV8@117743|Flavobacteriia,2PBPE@246874|Cryomorphaceae	976|Bacteroidetes	GT	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS3_k127_2597960_18	1341181.FLJC2902T_15060	5.55e-13	81.0	COG3209@1|root,COG3209@2|Bacteria,4NRDA@976|Bacteroidetes,1I3N8@117743|Flavobacteriia,2NZ0Z@237|Flavobacterium	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2597960_14	649349.Lbys_3349	5.46e-47	170.0	COG1694@1|root,COG1694@2|Bacteria,4NQ3H@976|Bacteroidetes,47QEV@768503|Cytophagia	976|Bacteroidetes	S	PFAM MazG nucleotide pyrophosphohydrolase	ypjD	-	-	-	-	-	-	-	-	-	-	-	MazG
TLS3_k127_2597960_0	1267211.KI669560_gene1599	3e-273	852.0	COG0043@1|root,COG0043@2|Bacteria,4NHHV@976|Bacteroidetes,1IR14@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
TLS3_k127_2597960_3	1048983.EL17_17200	7.555e-127	418.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,47JN4@768503|Cytophagia	976|Bacteroidetes	S	CinA-like protein	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
TLS3_k127_2597960_5	1121101.HMPREF1532_04127	2.479e-92	316.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,2FPCQ@200643|Bacteroidia,4AMUD@815|Bacteroidaceae	976|Bacteroidetes	L	COG2812 DNA polymerase III gamma tau subunits	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
TLS3_k127_2597960_8	742725.HMPREF9450_01042	2.717e-74	254.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,2FN36@200643|Bacteroidia,22UDM@171550|Rikenellaceae	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
TLS3_k127_2597960_15	1122605.KB893628_gene4397	1.309e-32	131.0	COG2940@1|root,COG2940@2|Bacteria,4NQ3D@976|Bacteroidetes	976|Bacteroidetes	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
TLS3_k127_2597960_13	1137281.D778_00398	8.98e-50	186.0	COG1120@1|root,COG1120@2|Bacteria,4NG1Q@976|Bacteroidetes,1HWNQ@117743|Flavobacteriia	976|Bacteroidetes	HP	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
TLS3_k127_2597960_10	906888.JCM19314_1146	1.523e-65	236.0	COG0609@1|root,COG0609@2|Bacteria,4NEDU@976|Bacteroidetes,1HXH4@117743|Flavobacteriia,3HJ6I@363408|Nonlabens	976|Bacteroidetes	U	FecCD transport family	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
TLS3_k127_2597960_16	163908.KB235896_gene2306	4.197e-16	79.0	COG0614@1|root,COG0614@2|Bacteria,1G37R@1117|Cyanobacteria,1HIY1@1161|Nostocales	1117|Cyanobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
TLS3_k127_2651118_9	1218108.KB908293_gene1057	1.027e-08	65.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,1HZ23@117743|Flavobacteriia	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
TLS3_k127_2651118_2	189753.AXAS01000011_gene7552	2.39e-104	350.0	COG1752@1|root,COG1752@2|Bacteria,1MVHW@1224|Proteobacteria,2TS4V@28211|Alphaproteobacteria,3JQYN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
TLS3_k127_2651118_5	1408433.JHXV01000001_gene721	2.4e-43	171.0	COG0457@1|root,COG0457@2|Bacteria,4PJHB@976|Bacteroidetes,1IMQ8@117743|Flavobacteriia,2PB7I@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
TLS3_k127_2651118_1	1408433.JHXV01000005_gene2527	1.319e-133	429.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,1HXAY@117743|Flavobacteriia,2PAIT@246874|Cryomorphaceae	976|Bacteroidetes	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
TLS3_k127_2651118_6	1380600.AUYN01000009_gene1739	4.468e-40	152.0	2AFHA@1|root,315HT@2|Bacteria,4NQ5F@976|Bacteroidetes,1I2SM@117743|Flavobacteriia	976|Bacteroidetes	S	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
TLS3_k127_2651118_0	929556.Solca_0345	7.487e-182	578.0	COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,1IQ7C@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
TLS3_k127_2651118_3	1408473.JHXO01000009_gene3354	1.575e-67	241.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,2FPK9@200643|Bacteroidia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
TLS3_k127_2651118_4	1121897.AUGO01000003_gene1763	1.124e-62	220.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1HY0Q@117743|Flavobacteriia,2NTPF@237|Flavobacterium	976|Bacteroidetes	J	Methyltransferase	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
TLS3_k127_2651118_8	1089547.KB913013_gene1345	1.884e-15	91.0	COG0689@1|root,COG2374@1|root,COG3210@1|root,COG3391@1|root,COG4733@1|root,COG0689@2|Bacteria,COG2374@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,4PPFY@976|Bacteroidetes,47KXR@768503|Cytophagia	976|Bacteroidetes	G	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,He_PIG
TLS3_k127_2651118_7	1122179.KB890430_gene4291	1.876e-34	134.0	2ASFK@1|root,31HVJ@2|Bacteria,4NQMQ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_265758_6	985255.APHJ01000040_gene316	7.112e-22	97.0	COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,1I2S3@117743|Flavobacteriia,2P6RJ@244698|Gillisia	976|Bacteroidetes	J	Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
TLS3_k127_265758_1	1229276.DI53_2210	3.636e-78	265.0	COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,1IRC9@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
TLS3_k127_265758_2	1150600.ADIARSV_3615	5.219e-67	230.0	COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes,1IS0B@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
TLS3_k127_265758_4	1123234.AUKI01000019_gene330	1.205e-33	131.0	COG0199@1|root,COG0199@2|Bacteria,4NQ6N@976|Bacteroidetes,1I2TX@117743|Flavobacteriia	976|Bacteroidetes	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
TLS3_k127_265758_0	929556.Solca_3015	1.205e-82	278.0	COG0094@1|root,COG0094@2|Bacteria,4NEGY@976|Bacteroidetes,1IPX4@117747|Sphingobacteriia	976|Bacteroidetes	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
TLS3_k127_265758_5	1408813.AYMG01000023_gene2121	5.113e-27	113.0	COG0198@1|root,COG0198@2|Bacteria,4NSTI@976|Bacteroidetes,1ISXS@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
TLS3_k127_265758_3	485917.Phep_0612	3.38e-39	146.0	COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,1ISEA@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
TLS3_k127_2658441_2	385682.AFSL01000100_gene37	2.819e-56	219.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,2FM1J@200643|Bacteroidia,3XJIH@558415|Marinilabiliaceae	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
TLS3_k127_2658441_3	760192.Halhy_1080	3.204e-55	202.0	COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,1IQKS@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	aviRb	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
TLS3_k127_2658441_7	1121287.AUMU01000011_gene672	2.09e-12	73.0	COG2885@1|root,COG2885@2|Bacteria,4NP5H@976|Bacteroidetes,1I23F@117743|Flavobacteriia,3ZRPM@59732|Chryseobacterium	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
TLS3_k127_2658441_5	926562.Oweho_1037	3.16e-34	136.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia,2PAZS@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
TLS3_k127_2658441_4	1408433.JHXV01000033_gene1145	7.82e-36	142.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia,2PAZS@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
TLS3_k127_2658441_0	929556.Solca_2412	0.0	1197.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1IPEY@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
TLS3_k127_2658441_1	1150600.ADIARSV_2742	3.285e-150	486.0	COG0513@1|root,COG0513@2|Bacteria,4NE4Z@976|Bacteroidetes,1IQWW@117747|Sphingobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase domain protein	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
TLS3_k127_2658441_8	1042376.AFPK01000044_gene2703	4.932e-05	57.0	COG3391@1|root,COG5492@1|root,COG3391@2|Bacteria,COG5492@2|Bacteria,4NIW7@976|Bacteroidetes,1I0II@117743|Flavobacteriia,407AB@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2658441_6	1123278.KB893387_gene4430	4.307e-21	110.0	COG1577@1|root,COG1874@1|root,COG3391@1|root,COG1577@2|Bacteria,COG1874@2|Bacteria,COG3391@2|Bacteria,4PPRK@976|Bacteroidetes,47TYG@768503|Cytophagia	976|Bacteroidetes	G	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2661920_2	269798.CHU_2983	8.086e-14	74.0	COG4829@1|root,COG4829@2|Bacteria,4NS7J@976|Bacteroidetes,47RN0@768503|Cytophagia	976|Bacteroidetes	Q	muconolactone delta-isomerase	-	-	-	-	-	-	-	-	-	-	-	-	MIase
TLS3_k127_2661920_3	1308866.J416_02089	2.222e-13	83.0	COG2244@1|root,COG2244@2|Bacteria,1TR7A@1239|Firmicutes,4HEKF@91061|Bacilli	91061|Bacilli	S	Polysaccharide biosynthesis protein	cps2J	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
TLS3_k127_2661920_0	1120965.AUBV01000012_gene1433	2.488e-53	196.0	COG2227@1|root,COG2227@2|Bacteria,4NTKJ@976|Bacteroidetes,47TGS@768503|Cytophagia	976|Bacteroidetes	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_2661920_1	1227739.Hsw_1651	3.659e-29	131.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,47WGT@768503|Cytophagia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2661920_4	1227499.C493_21166	0.0002295	53.0	arCOG08925@1|root,arCOG08925@2157|Archaea,2XVAT@28890|Euryarchaeota,23UZ0@183963|Halobacteria	183963|Halobacteria	S	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
TLS3_k127_2663116_1	1492737.FEM08_07500	4.007e-41	158.0	COG0628@1|root,COG0628@2|Bacteria,4NN3B@976|Bacteroidetes,1HYEH@117743|Flavobacteriia,2NUR6@237|Flavobacterium	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS3_k127_2663116_2	1202532.FF52_19450	1.398e-17	90.0	29W63@1|root,30HR7@2|Bacteria,4NZAJ@976|Bacteroidetes,1IMXB@117743|Flavobacteriia,2NW2A@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2663116_0	468059.AUHA01000002_gene1347	1.005e-254	789.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1IQ23@117747|Sphingobacteriia	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
TLS3_k127_2697217_5	945550.VISI1226_12616	2.571e-11	67.0	COG0300@1|root,COG0300@2|Bacteria,1RG9T@1224|Proteobacteria,1S48Y@1236|Gammaproteobacteria,1Y2H1@135623|Vibrionales	135623|Vibrionales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
TLS3_k127_2697217_4	318464.IO99_10750	6.531e-22	111.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia,36MUH@31979|Clostridiaceae	186801|Clostridia	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
TLS3_k127_2697217_2	1041826.FCOL_10720	1.989e-117	384.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1HX06@117743|Flavobacteriia,2NST8@237|Flavobacterium	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
TLS3_k127_2697217_3	1349822.NSB1T_04655	2.613e-84	295.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,2FMHC@200643|Bacteroidia,22WJ1@171551|Porphyromonadaceae	976|Bacteroidetes	M	ABC transporter permease	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
TLS3_k127_2697217_1	153721.MYP_3495	3.323e-127	422.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,47KTI@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised conserved protein UCP016719	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
TLS3_k127_2697217_0	929556.Solca_1867	1.295e-172	552.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1IP3U@117747|Sphingobacteriia	976|Bacteroidetes	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bfmBB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS3_k127_2697217_6	1122179.KB890418_gene3821	2.702e-09	59.0	COG1284@1|root,COG1284@2|Bacteria,4NG9F@976|Bacteroidetes,1IPVB@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
TLS3_k127_2744479_5	1121904.ARBP01000007_gene2905	7.414e-45	166.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,47JXB@768503|Cytophagia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TLS3_k127_2744479_4	1168034.FH5T_13680	5.039e-51	193.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,2FP8Y@200643|Bacteroidia	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2744479_1	1121129.KB903359_gene1255	2.511e-99	334.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,2FNXM@200643|Bacteroidia,22XC0@171551|Porphyromonadaceae	976|Bacteroidetes	S	Von Willebrand factor type A domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
TLS3_k127_2744479_0	1121904.ARBP01000007_gene2909	1.851e-99	336.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,47JUP@768503|Cytophagia	2|Bacteria	S	PFAM von Willebrand factor type A	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
TLS3_k127_2744479_7	485917.Phep_1483	4.474e-24	111.0	COG0457@1|root,COG0457@2|Bacteria,4NH2K@976|Bacteroidetes,1ISXE@117747|Sphingobacteriia	976|Bacteroidetes	S	TPR repeat	batC	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
TLS3_k127_2744479_3	585543.HMPREF0969_03209	5.529e-85	304.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,2FMK5@200643|Bacteroidia,4AK7T@815|Bacteroidaceae	976|Bacteroidetes	S	COG NOG06393 non supervised orthologous group	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
TLS3_k127_2744479_6	1121904.ARBP01000007_gene2912	6.51e-37	149.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes	976|Bacteroidetes	T	tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
TLS3_k127_2744479_2	1408433.JHXV01000002_gene459	1.331e-91	304.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,1HXXW@117743|Flavobacteriia,2PADK@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
TLS3_k127_278361_7	1197477.IA57_04350	6.065e-35	144.0	COG1835@1|root,COG1835@2|Bacteria,4NIR9@976|Bacteroidetes,1HXXY@117743|Flavobacteriia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS3_k127_278361_8	1122176.KB903532_gene2521	5.552e-10	73.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_278361_2	649349.Lbys_0384	1.135e-74	282.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,47XXU@768503|Cytophagia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
TLS3_k127_278361_5	1349785.BAUG01000019_gene1350	5.441e-57	212.0	COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,1HZFD@117743|Flavobacteriia	976|Bacteroidetes	I	penicillin-binding protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_278361_1	1048983.EL17_19570	3.863e-89	299.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,47N62@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_278361_3	945713.IALB_0308	3.037e-66	239.0	COG2972@1|root,COG2972@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	2TM,His_kinase
TLS3_k127_278361_0	926562.Oweho_0145	1.134e-102	349.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1HXTE@117743|Flavobacteriia,2PA5V@246874|Cryomorphaceae	976|Bacteroidetes	M	PPIC-type PPIASE domain	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
TLS3_k127_278361_6	1121859.KB890750_gene201	2.501e-43	183.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Lipase_GDSL_2,Metallophos,SASA,SLH
TLS3_k127_279814_3	706436.HMPREF9074_08321	1.331e-22	99.0	2EI8K@1|root,33BZY@2|Bacteria,4PBT0@976|Bacteroidetes,1IFM2@117743|Flavobacteriia,1ET71@1016|Capnocytophaga	976|Bacteroidetes	S	TRL-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	TRL
TLS3_k127_279814_2	755732.Fluta_0165	2.929e-32	129.0	COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,1I1XK@117743|Flavobacteriia,2PB63@246874|Cryomorphaceae	976|Bacteroidetes	L	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
TLS3_k127_279814_1	1121889.AUDM01000002_gene418	1.507e-129	422.0	COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,1HWMJ@117743|Flavobacteriia,2NTWP@237|Flavobacterium	976|Bacteroidetes	EJ	1-alkyl-2-acetylglycerophosphocholine esterase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
TLS3_k127_279814_0	1358423.N180_18965	4.081e-216	678.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,4NDZ9@976|Bacteroidetes,1IQU6@117747|Sphingobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
TLS3_k127_279814_4	1185876.BN8_01572	5.825e-11	64.0	COG1835@1|root,COG1835@2|Bacteria,4NIR9@976|Bacteroidetes,47KQ0@768503|Cytophagia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS3_k127_2818343_0	743722.Sph21_0777	2.175e-210	678.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1IQD3@117747|Sphingobacteriia	976|Bacteroidetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_2818343_4	1121904.ARBP01000010_gene2315	9.033e-46	172.0	COG2010@1|root,COG2010@2|Bacteria,4NSUK@976|Bacteroidetes,47R5S@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,SirB
TLS3_k127_2818343_1	742725.HMPREF9450_01021	8.272e-172	547.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,2FM9T@200643|Bacteroidia,22U3K@171550|Rikenellaceae	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
TLS3_k127_2818343_3	1334046.AYTB01000013_gene508	3.245e-52	190.0	COG1247@1|root,COG1247@2|Bacteria,1V3V3@1239|Firmicutes,4HHNY@91061|Bacilli,26IKX@186818|Planococcaceae	91061|Bacilli	M	Acetyltransferase (GNAT) domain	ywnH	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_4
TLS3_k127_2818343_2	926549.KI421517_gene2090	4.736e-68	251.0	COG2706@1|root,COG2706@2|Bacteria,4PMCI@976|Bacteroidetes,47Y0V@768503|Cytophagia	976|Bacteroidetes	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2818343_5	153721.MYP_3913	0.0003366	53.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,47MNQ@768503|Cytophagia	976|Bacteroidetes	O	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA,SprB
TLS3_k127_2819492_1	1356852.N008_01410	1.089e-113	372.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,47KM0@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
TLS3_k127_2819492_0	468059.AUHA01000003_gene1886	4.403e-165	526.0	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,1INXN@117747|Sphingobacteriia	976|Bacteroidetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS3_k127_2819492_2	1094466.KQS_04535	1.14e-66	240.0	COG0395@1|root,COG0395@2|Bacteria,4NIYE@976|Bacteroidetes,1HYEP@117743|Flavobacteriia,2NU97@237|Flavobacterium	976|Bacteroidetes	G	Inward rectifier potassium channel	irk	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
TLS3_k127_2819492_3	1123234.AUKI01000017_gene2649	1.453e-52	194.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1HXP2@117743|Flavobacteriia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
TLS3_k127_2819492_4	869213.JCM21142_31019	4.619e-31	127.0	COG0526@1|root,COG0526@2|Bacteria,4NQ9U@976|Bacteroidetes,47RGU@768503|Cytophagia	976|Bacteroidetes	CO	Thioredoxin	trxC	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin,Thioredoxin_8
TLS3_k127_2819492_5	1047013.AQSP01000122_gene2223	0.0003933	50.0	COG3291@1|root,COG3291@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_2,CHU_C,FlgD_ig,Glyco_hydro_6,PKD,VCBS
TLS3_k127_2867163_3	1227739.Hsw_0900	2.192e-29	123.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,47KAN@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
TLS3_k127_2867163_0	313606.M23134_00610	6.439e-98	331.0	COG3081@1|root,COG3081@2|Bacteria,4NFSN@976|Bacteroidetes,47MMD@768503|Cytophagia	976|Bacteroidetes	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
TLS3_k127_2867163_2	1123248.KB893386_gene1827	2.26e-38	146.0	COG4068@1|root,COG4068@2|Bacteria,4NQ3Z@976|Bacteroidetes,1ITN4@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
TLS3_k127_2867163_1	1237149.C900_04618	9.478e-72	246.0	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,47JH8@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
TLS3_k127_2869448_8	153721.MYP_2944	2.563e-32	130.0	2CGGN@1|root,2ZX47@2|Bacteria,4NNTI@976|Bacteroidetes,47QF4@768503|Cytophagia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2869448_4	153721.MYP_2943	2.579e-88	306.0	28HAZ@1|root,2Z7N5@2|Bacteria,4NH23@976|Bacteroidetes,47MQC@768503|Cytophagia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2869448_2	929713.NIASO_09025	5.955e-119	394.0	COG0438@1|root,COG0438@2|Bacteria,4NEZI@976|Bacteroidetes,1IPPF@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_2869448_5	926549.KI421517_gene978	5.19e-77	261.0	COG1607@1|root,COG1607@2|Bacteria,4NMK1@976|Bacteroidetes,47N9Z@768503|Cytophagia	976|Bacteroidetes	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
TLS3_k127_2869448_1	1123278.KB893477_gene3633	1.726e-139	450.0	COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,47KTC@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
TLS3_k127_2869448_9	1123278.KB893477_gene3633	7.843e-12	67.0	COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,47KTC@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
TLS3_k127_2869448_7	742725.HMPREF9450_01118	6.992e-59	213.0	2BB8B@1|root,324R0@2|Bacteria,4NQG8@976|Bacteroidetes,2FXHA@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2869448_0	860228.Ccan_18310	6.322e-252	784.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,1HXK2@117743|Flavobacteriia,1ER4P@1016|Capnocytophaga	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
TLS3_k127_2869448_3	1392489.JPOL01000002_gene2817	7.557e-119	391.0	COG0111@1|root,COG0111@2|Bacteria,4NDVN@976|Bacteroidetes,1HWXS@117743|Flavobacteriia,2XI3X@283735|Leeuwenhoekiella	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TLS3_k127_2869448_6	1121931.AUHG01000016_gene984	2.467e-71	249.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,1HX17@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised conserved protein UCP033563	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
TLS3_k127_2929492_2	909613.UO65_3068	0.0001746	44.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria,4E0MV@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
TLS3_k127_2929492_1	224324.aq_926	3.391e-13	70.0	COG1801@1|root,COG1801@2|Bacteria,2G44R@200783|Aquificae	200783|Aquificae	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
TLS3_k127_2938117_6	1227739.Hsw_0453	1.643e-29	120.0	COG0531@1|root,COG0531@2|Bacteria,4NH7J@976|Bacteroidetes,47NNC@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
TLS3_k127_2938117_0	153721.MYP_4938	8.025e-192	638.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
TLS3_k127_2938117_8	700598.Niako_1497	1.269e-12	82.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,F5_F8_type_C,Pectate_lyase_3
TLS3_k127_2938117_3	643867.Ftrac_3154	5.81e-67	240.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,47MUX@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_2938117_7	1122179.KB890469_gene607	1.714e-16	94.0	COG2931@1|root,COG4886@1|root,COG2931@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	VCBS
TLS3_k127_2938117_4	1189619.pgond44_08240	1.088e-60	233.0	COG2866@1|root,COG2911@1|root,COG2866@2|Bacteria,COG2911@2|Bacteria,4PMMV@976|Bacteroidetes,1IMVC@117743|Flavobacteriia	976|Bacteroidetes	E	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2938117_2	929562.Emtol_3225	4.016e-91	315.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,47JCK@768503|Cytophagia	976|Bacteroidetes	CP	COGs COG1668 ABC-type Na efflux pump permease component	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
TLS3_k127_2938117_1	1408473.JHXO01000006_gene1216	1.646e-111	368.0	COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,2FMK3@200643|Bacteroidia	976|Bacteroidetes	S	ABC transporter, ATP-binding protein	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
TLS3_k127_2938117_5	1168034.FH5T_03335	3.509e-40	155.0	COG2928@1|root,COG2928@2|Bacteria,4NR4F@976|Bacteroidetes,2FZVE@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
TLS3_k127_2957878_0	1408433.JHXV01000031_gene3251	7.791e-67	250.0	COG1629@1|root,COG1629@2|Bacteria,4P929@976|Bacteroidetes,1IB8G@117743|Flavobacteriia	976|Bacteroidetes	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2957878_3	269798.CHU_0746	4.508e-23	101.0	COG0864@1|root,COG0864@2|Bacteria,4NV9H@976|Bacteroidetes,47SQU@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	RHH_3
TLS3_k127_2957878_2	1189612.A33Q_0549	5.823e-36	139.0	COG2337@1|root,COG2337@2|Bacteria,4NTCI@976|Bacteroidetes,47RQE@768503|Cytophagia	976|Bacteroidetes	L	Toxic component of a toxin-antitoxin (TA) module	chpA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
TLS3_k127_2957878_1	471854.Dfer_3682	1.937e-49	180.0	COG4914@1|root,COG4914@2|Bacteria,4NTDW@976|Bacteroidetes,47XU6@768503|Cytophagia	976|Bacteroidetes	S	Nucleotidyl transferase of unknown function (DUF2204)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
TLS3_k127_2967707_0	1173028.ANKO01000041_gene3172	3.786e-73	263.0	COG0642@1|root,COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1G3QY@1117|Cyanobacteria,1HA15@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_8,PAS_9,Response_reg
TLS3_k127_2967707_4	247490.KSU1_D0866	3.606e-49	181.0	COG0745@1|root,COG0745@2|Bacteria	247490.KSU1_D0866|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2967707_5	373994.Riv7116_3386	2.594e-28	132.0	COG0642@1|root,COG0745@1|root,COG2204@1|root,COG0745@2|Bacteria,COG2204@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HKT0@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_2967707_2	1408433.JHXV01000010_gene527	1.427e-68	258.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4PPWM@976|Bacteroidetes,1IKWE@117743|Flavobacteriia,2PBIK@246874|Cryomorphaceae	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	srrB	-	-	-	-	-	-	-	-	-	-	-	CBS,HAMP,SpoIIE,dCache_1
TLS3_k127_2967707_7	504472.Slin_3149	7.64e-05	51.0	COG4565@1|root,COG4565@2|Bacteria,4PN9H@976|Bacteroidetes	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_2967707_6	1453498.LG45_14560	2.359e-08	59.0	2DH3W@1|root,2ZYAK@2|Bacteria,4PCVZ@976|Bacteroidetes,1IDDT@117743|Flavobacteriia,2NY3B@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2967707_1	1086011.HJ01_01597	5.988e-70	243.0	COG1018@1|root,COG1018@2|Bacteria,4NM4J@976|Bacteroidetes,1I1RH@117743|Flavobacteriia,2NZXX@237|Flavobacterium	976|Bacteroidetes	C	FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,FAD_binding_8,NAD_binding_1
TLS3_k127_2967707_3	269798.CHU_2308	3.256e-59	215.0	COG0596@1|root,COG0596@2|Bacteria,4PM24@976|Bacteroidetes,47Y00@768503|Cytophagia	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,CMD
TLS3_k127_2993111_0	926549.KI421517_gene3631	6.379e-36	139.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,47MXR@768503|Cytophagia	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_2993111_1	1227739.Hsw_2540	2.084e-31	132.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,47NAQ@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_2993111_3	679935.Alfi_1659	6.414e-15	85.0	COG4585@1|root,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,2FRZ7@200643|Bacteroidia,22UEE@171550|Rikenellaceae	976|Bacteroidetes	T	histidine kinase DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
TLS3_k127_2993111_4	391596.PBAL39_21860	7.191e-09	64.0	2AT0W@1|root,31IGS@2|Bacteria,4PK6Z@976|Bacteroidetes,1IZH8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2999704_2	1122978.AUFP01000026_gene845	5.664e-58	209.0	COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,2FM5H@200643|Bacteroidia	976|Bacteroidetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
TLS3_k127_2999704_0	153721.MYP_1661	1.053e-139	463.0	COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes,47NYD@768503|Cytophagia	976|Bacteroidetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
TLS3_k127_2999704_1	1121373.KB903621_gene1905	2.062e-108	355.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,47KRK@768503|Cytophagia	976|Bacteroidetes	L	PFAM Endonuclease Exonuclease phosphatase	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
TLS3_k127_3014734_2	153721.MYP_1955	2.085e-05	55.0	COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes,47MRT@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane chaperone Skp (OmpH)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TLS3_k127_3014734_0	983544.Lacal_0262	7.431e-46	169.0	COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,1I23U@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PRA-PH
TLS3_k127_3014734_1	1279009.ADICEAN_01848	4.271e-40	156.0	COG0705@1|root,COG0705@2|Bacteria,4NECA@976|Bacteroidetes,47N8U@768503|Cytophagia	976|Bacteroidetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TLS3_k127_3017472_2	1237149.C900_04101	3.447e-129	421.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,47JX0@768503|Cytophagia	976|Bacteroidetes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
TLS3_k127_3017472_3	485918.Cpin_0714	2.876e-125	412.0	COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,1IQHU@117747|Sphingobacteriia	976|Bacteroidetes	E	Aminopeptidase	pepC	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1,Peptidase_C1_2
TLS3_k127_3017472_6	1168289.AJKI01000002_gene2502	8.983e-32	128.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,2FUPU@200643|Bacteroidia,3XK7D@558415|Marinilabiliaceae	976|Bacteroidetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
TLS3_k127_3017472_4	1168034.FH5T_08815	5.663e-118	412.0	COG1729@1|root,COG1729@2|Bacteria,4PKGA@976|Bacteroidetes,2G3G6@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
TLS3_k127_3017472_1	269798.CHU_0279	9.016e-147	470.0	COG0524@1|root,COG0524@2|Bacteria,4NFJ9@976|Bacteroidetes,47KA2@768503|Cytophagia	976|Bacteroidetes	G	pfkB family carbohydrate kinase	ydjH	-	-	-	-	-	-	-	-	-	-	-	PfkB
TLS3_k127_3017472_5	236814.IX39_10045	3.097e-43	163.0	COG0642@1|root,COG2205@2|Bacteria,4NFYN@976|Bacteroidetes,1HZ6X@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
TLS3_k127_3017472_7	1131812.JQMS01000001_gene2141	5.013e-17	81.0	COG0642@1|root,COG2205@2|Bacteria,4NFYN@976|Bacteroidetes,1HZ6X@117743|Flavobacteriia,2P05M@237|Flavobacterium	976|Bacteroidetes	T	Domain of unknown function (DUF4118)	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
TLS3_k127_3017472_12	1034807.FBFL15_2463	0.0005303	44.0	COG0642@1|root,COG2205@2|Bacteria,4NFYN@976|Bacteroidetes,1HZ6X@117743|Flavobacteriia,2P05M@237|Flavobacterium	976|Bacteroidetes	T	Domain of unknown function (DUF4118)	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
TLS3_k127_3017472_10	1121011.AUCB01000013_gene172	2.884e-06	50.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1IG1F@117743|Flavobacteriia,23HZG@178469|Arenibacter	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
TLS3_k127_3017472_11	1192868.CAIU01000020_gene2903	0.0004742	44.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,43GTD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	Osmosensitive K channel histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
TLS3_k127_3017472_9	755732.Fluta_3668	4.475e-08	55.0	COG0745@1|root,COG0745@2|Bacteria,4NIQC@976|Bacteroidetes,1HZUW@117743|Flavobacteriia	976|Bacteroidetes	T	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_3017472_0	1121896.JMLU01000025_gene692	1.032e-179	566.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,1HYI9@117743|Flavobacteriia,2NSQU@237|Flavobacterium	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
TLS3_k127_3027189_2	742766.HMPREF9455_02907	7.665e-11	71.0	COG5492@1|root,COG5492@2|Bacteria,4PM2D@976|Bacteroidetes	976|Bacteroidetes	N	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_3027189_6	1380600.AUYN01000001_gene2859	0.0002636	54.0	COG2356@1|root,COG2931@1|root,COG2356@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
TLS3_k127_3027189_1	1313421.JHBV01000049_gene57	5.473e-34	150.0	COG2133@1|root,COG3209@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,CHU_C,Copper-bind,DUF1080,GSDH,PKD,SprB
TLS3_k127_3027189_4	880073.Calab_1754	1.033e-06	62.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.4,3.4.21.66	ko:K01179,ko:K08651	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH5,GH9	-	Autotransporter,PKD,Peptidase_S8,Peptidase_S8_N,fn3
TLS3_k127_3027189_3	714943.Mucpa_3747	5.319e-09	69.0	COG4733@1|root,COG4733@2|Bacteria,4NTXR@976|Bacteroidetes,1IZ2D@117747|Sphingobacteriia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
TLS3_k127_3027189_0	1121890.AUDO01000013_gene1523	4.695e-229	711.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1HWZ3@117743|Flavobacteriia,2NT3U@237|Flavobacterium	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
TLS3_k127_3027189_5	1233950.IW22_03925	1.962e-05	50.0	2E347@1|root,32Y4A@2|Bacteria,4PKYE@976|Bacteroidetes,1IJHB@117743|Flavobacteriia,3ZS1E@59732|Chryseobacterium	976|Bacteroidetes	S	Secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3039420_0	1223410.KN050846_gene2163	3.704e-66	228.0	COG3485@1|root,COG3485@2|Bacteria,4NEZ1@976|Bacteroidetes,1I01Q@117743|Flavobacteriia	976|Bacteroidetes	Q	Dioxygenase	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
TLS3_k127_3039420_2	1191523.MROS_0899	6.569e-19	97.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_3039420_1	5762.XP_002669755.1	2.527e-31	134.0	COG0702@1|root,2QQEA@2759|Eukaryota	2759|Eukaryota	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
TLS3_k127_3057240_1	755732.Fluta_4031	3.145e-45	167.0	COG0579@1|root,COG0579@2|Bacteria,4NE0B@976|Bacteroidetes,1HZQJ@117743|Flavobacteriia,2PACG@246874|Cryomorphaceae	976|Bacteroidetes	S	FAD dependent oxidoreductase	lhgO	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
TLS3_k127_3057240_0	1121896.JMLU01000011_gene1505	1.491e-98	329.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1HXYS@117743|Flavobacteriia,2NS8Z@237|Flavobacterium	976|Bacteroidetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
TLS3_k127_3057240_3	926551.KB900705_gene578	1.64e-44	167.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,1I2CB@117743|Flavobacteriia,1ERSV@1016|Capnocytophaga	976|Bacteroidetes	F	pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
TLS3_k127_3057240_2	1408433.JHXV01000009_gene1349	5.492e-45	171.0	COG2208@1|root,COG2208@2|Bacteria,4NI98@976|Bacteroidetes,1IMQG@117743|Flavobacteriia,2PBAV@246874|Cryomorphaceae	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
TLS3_k127_3069931_3	643473.KB235930_gene3558	1.822e-23	107.0	COG2706@1|root,COG2931@1|root,COG3391@1|root,COG2706@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,1GQ7W@1117|Cyanobacteria,1HTNJ@1161|Nostocales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4114)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114,FG-GAP
TLS3_k127_3069931_1	1123037.AUDE01000032_gene2266	1.103e-51	184.0	COG1143@1|root,COG1143@2|Bacteria,4PKCQ@976|Bacteroidetes,1IJ7N@117743|Flavobacteriia	976|Bacteroidetes	C	ferredoxin	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
TLS3_k127_3069931_0	746697.Aeqsu_2780	9.604e-97	327.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,1HWNH@117743|Flavobacteriia	976|Bacteroidetes	C	acyl-CoA reductase	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
TLS3_k127_3069931_4	888832.HMPREF9420_0273	5.064e-18	94.0	COG3291@1|root,COG3291@2|Bacteria,4NPBK@976|Bacteroidetes,2FT10@200643|Bacteroidia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_3069931_2	153721.MYP_2168	5.454e-49	188.0	COG3842@1|root,COG3842@2|Bacteria,4NEZ6@976|Bacteroidetes,47N5M@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the ABC transporter superfamily	fbpC2	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
TLS3_k127_3129931_1	755732.Fluta_3106	3.412e-122	417.0	COG3291@1|root,COG3291@2|Bacteria,4PI0I@976|Bacteroidetes,1I5WG@117743|Flavobacteriia,2PBH4@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_3129931_2	755732.Fluta_3107	5.563e-103	344.0	COG4772@1|root,COG4772@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014,ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.2	-	-	Plug,PorP_SprF,STN,TonB_dep_Rec
TLS3_k127_3129931_0	755732.Fluta_3108	5.585e-179	584.0	COG1729@1|root,COG2885@1|root,COG1729@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia,2PBBP@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
TLS3_k127_3129931_5	573413.Spirs_3748	1.064e-21	96.0	COG1254@1|root,COG1254@2|Bacteria,2J8D1@203691|Spirochaetes	203691|Spirochaetes	C	Acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
TLS3_k127_3129931_3	1046627.BZARG_1218	5.537e-48	181.0	COG3279@1|root,COG3279@2|Bacteria,4NEXZ@976|Bacteroidetes,1HZ0B@117743|Flavobacteriia	976|Bacteroidetes	T	COG3279 Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_3129931_4	1469557.JSWF01000030_gene3543	3.155e-44	178.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
TLS3_k127_3150607_3	1313421.JHBV01000029_gene2024	7.045e-28	130.0	COG3291@1|root,COG3391@1|root,COG4409@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4409@2|Bacteria,4PPK0@976|Bacteroidetes	976|Bacteroidetes	G	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3150607_2	1313421.JHBV01000007_gene4227	7.441e-30	137.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
TLS3_k127_3150607_0	1270196.JCKI01000008_gene1557	0.0	1204.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1IQBM@117747|Sphingobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
TLS3_k127_3150607_1	1408433.JHXV01000010_gene533	5.145e-65	228.0	COG1249@1|root,COG1249@2|Bacteria,4NJ2P@976|Bacteroidetes,1IGB0@117743|Flavobacteriia,2PBK6@246874|Cryomorphaceae	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_3190947_8	388413.ALPR1_05460	1.926e-38	150.0	COG2208@1|root,COG2208@2|Bacteria,4NI98@976|Bacteroidetes,47KA0@768503|Cytophagia	976|Bacteroidetes	KT	PFAM Stage II sporulation protein E (SpoIIE)	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
TLS3_k127_3190947_2	1168034.FH5T_03525	3.322e-117	394.0	COG3307@1|root,COG3307@2|Bacteria,4NMYT@976|Bacteroidetes	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
TLS3_k127_3190947_7	1453500.AT05_07465	2.725e-46	179.0	COG3206@1|root,COG3206@2|Bacteria,4NSFM@976|Bacteroidetes	976|Bacteroidetes	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3190947_1	1168034.FH5T_06745	3.628e-120	403.0	COG2244@1|root,COG2244@2|Bacteria,4NPGZ@976|Bacteroidetes,2G3BA@200643|Bacteroidia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
TLS3_k127_3190947_0	1168034.FH5T_06740	2.52e-131	428.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,2FPWJ@200643|Bacteroidia	976|Bacteroidetes	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_3190947_4	1123248.KB893386_gene1874	2.644e-95	326.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,1IQKA@117747|Sphingobacteriia	976|Bacteroidetes	M	transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
TLS3_k127_3190947_5	1122176.KB903598_gene4643	2.942e-52	193.0	2EA9Q@1|root,334E4@2|Bacteria,4NX5I@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3190947_3	714943.Mucpa_5182	1.295e-107	354.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1IQ8R@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_3190947_6	1341181.FLJC2902T_22700	7.418e-50	199.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NSSE@237|Flavobacterium	976|Bacteroidetes	O	gliding motility-associated C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
TLS3_k127_3201000_3	1349785.BAUG01000057_gene2506	5.932e-16	79.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,1HX2U@117743|Flavobacteriia	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
TLS3_k127_3201000_1	926562.Oweho_1584	1.281e-39	161.0	2E7J5@1|root,3321E@2|Bacteria,4NWSR@976|Bacteroidetes,1I9ID@117743|Flavobacteriia,2PB0F@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
TLS3_k127_3201000_0	1408433.JHXV01000014_gene3639	1.248e-41	167.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IFTS@117743|Flavobacteriia,2PBTH@246874|Cryomorphaceae	976|Bacteroidetes	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_3201000_2	153721.MYP_509	2.513e-19	98.0	COG3291@1|root,COG3291@2|Bacteria,4NJW2@976|Bacteroidetes,47K98@768503|Cytophagia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_3219185_1	391596.PBAL39_10016	9.967e-73	249.0	COG0494@1|root,COG0494@2|Bacteria,4NMHV@976|Bacteroidetes,1IRW6@117747|Sphingobacteriia	976|Bacteroidetes	L	NUDIX domain	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_3219185_0	1313421.JHBV01000043_gene3214	2.517e-90	308.0	COG2222@1|root,COG2222@2|Bacteria,4NIX0@976|Bacteroidetes	976|Bacteroidetes	M	Bifunctional phosphoglucose phosphomannose isomerase	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
TLS3_k127_3219185_2	1237149.C900_02110	3.516e-56	198.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,47KKV@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
TLS3_k127_3222314_0	1406840.Q763_04910	5.165e-252	789.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,1HX75@117743|Flavobacteriia,2NTDV@237|Flavobacterium	976|Bacteroidetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
TLS3_k127_3222314_5	926562.Oweho_2578	2.46e-84	302.0	COG2931@1|root,COG2931@2|Bacteria,4P2B3@976|Bacteroidetes,1I8WB@117743|Flavobacteriia,2PBTD@246874|Cryomorphaceae	976|Bacteroidetes	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3222314_3	926562.Oweho_2197	3.347e-149	505.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes,1I840@117743|Flavobacteriia,2PBAC@246874|Cryomorphaceae	976|Bacteroidetes	Q	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_3222314_4	592029.DDD_3295	1.423e-120	399.0	COG0144@1|root,COG0144@2|Bacteria,4NEV7@976|Bacteroidetes,1HXH7@117743|Flavobacteriia,3HJNY@363408|Nonlabens	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
TLS3_k127_3222314_12	1123054.KB907704_gene1034	3.327e-23	110.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K03406,ko:K07242	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	2.A.63	-	-	DUF4040,SBP_bac_3
TLS3_k127_3222314_7	237368.SCABRO_02251	1.312e-74	259.0	COG1218@1|root,COG1218@2|Bacteria	2|Bacteria	P	3'(2'),5'-bisphosphate nucleotidase activity	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
TLS3_k127_3222314_2	755732.Fluta_1187	2.872e-178	566.0	COG0027@1|root,COG0027@2|Bacteria,4PKAW@976|Bacteroidetes,1HYDF@117743|Flavobacteriia,2PBJD@246874|Cryomorphaceae	976|Bacteroidetes	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,Epimerase
TLS3_k127_3222314_1	509635.N824_02835	1.208e-195	616.0	COG1060@1|root,COG1060@2|Bacteria,4NGTU@976|Bacteroidetes,1IQI2@117747|Sphingobacteriia	976|Bacteroidetes	H	Radical SAM	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
TLS3_k127_3222314_14	1250006.JHZZ01000001_gene1560	3.481e-05	57.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	2.1.1.72,3.1.4.46,3.2.1.1	ko:K00571,ko:K01126,ko:K01176	ko00500,ko00564,ko01100,ko04973,map00500,map00564,map01100,map04973	-	R01030,R01470,R02108,R02112,R11262	RC00017,RC00425	ko00000,ko00001,ko01000,ko02048	-	GH13	-	CBM_35,CHU_C,PKD
TLS3_k127_3222314_13	485918.Cpin_4166	1.999e-05	57.0	COG2304@1|root,COG3291@1|root,COG3386@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,4NDZC@976|Bacteroidetes	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
TLS3_k127_3222314_10	762903.Pedsa_2409	1.213e-30	139.0	COG2911@1|root,COG3210@1|root,COG4625@1|root,COG5492@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG5492@2|Bacteria,4NHHA@976|Bacteroidetes	976|Bacteroidetes	E	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_4,CHU_C,Calx-beta,He_PIG,NHL,TIG,fn3
TLS3_k127_3222314_9	929713.NIASO_15405	2.204e-37	145.0	COG2315@1|root,COG2315@2|Bacteria,4NS6J@976|Bacteroidetes,1IT89@117747|Sphingobacteriia	976|Bacteroidetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
TLS3_k127_3222314_6	762903.Pedsa_2967	6.331e-82	280.0	COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,1INP5@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
TLS3_k127_3222314_8	755732.Fluta_1107	2.21e-46	175.0	COG0848@1|root,COG0848@2|Bacteria,4NMT4@976|Bacteroidetes,1I46Q@117743|Flavobacteriia	976|Bacteroidetes	U	Biopolymer transporter ExbD	exbD1	-	-	-	-	-	-	-	-	-	-	-	ExbD
TLS3_k127_3222314_11	755732.Fluta_1108	2.356e-28	116.0	COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,1I08G@117743|Flavobacteriia	976|Bacteroidetes	U	Biopolymer transporter ExbD	exbD2	-	-	-	-	-	-	-	-	-	-	-	ExbD
TLS3_k127_3227058_3	761193.Runsl_1762	3.251e-46	171.0	COG3781@1|root,COG3781@2|Bacteria,4NEB1@976|Bacteroidetes,47N85@768503|Cytophagia	976|Bacteroidetes	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
TLS3_k127_3227058_0	925409.KI911562_gene2618	2.455e-200	631.0	COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,1INU3@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
TLS3_k127_3227058_4	926562.Oweho_1769	1.433e-11	75.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1HZRC@117743|Flavobacteriia,2PANF@246874|Cryomorphaceae	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_3227058_1	1121904.ARBP01000001_gene5377	1.303e-153	497.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47MBT@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
TLS3_k127_3227058_5	1120965.AUBV01000003_gene346	6.803e-07	55.0	COG5512@1|root,COG5512@2|Bacteria,4NXIK@976|Bacteroidetes,47S8C@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
TLS3_k127_3227058_2	1392489.JPOL01000002_gene1374	2.298e-68	236.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,1HYJ9@117743|Flavobacteriia,2XJ8E@283735|Leeuwenhoekiella	976|Bacteroidetes	F	AIR carboxylase	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
TLS3_k127_3232569_3	929556.Solca_2021	5.916e-68	232.0	COG1788@1|root,COG1788@2|Bacteria,4NF3T@976|Bacteroidetes,1IQP0@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoA	-	2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01031,ko:K01034	ko00072,ko00280,ko00310,ko00362,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00362,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R02990,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
TLS3_k127_3232569_0	755732.Fluta_0389	4.653e-148	482.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia,2PBCE@246874|Cryomorphaceae	976|Bacteroidetes	M	membrane protein involved in D-alanine export	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
TLS3_k127_3232569_2	755732.Fluta_0390	2.436e-89	305.0	2A8PB@1|root,30XRW@2|Bacteria,4PB9W@976|Bacteroidetes,1IMQZ@117743|Flavobacteriia,2PBHI@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3232569_1	468059.AUHA01000005_gene2577	1.256e-119	386.0	COG2057@1|root,COG2057@2|Bacteria,4NG9J@976|Bacteroidetes,1IQBC@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoB	-	2.8.3.5,2.8.3.6	ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
TLS3_k127_3232569_4	1227739.Hsw_0103	8.417e-49	183.0	COG0463@1|root,COG0463@2|Bacteria,4PP1X@976|Bacteroidetes,47RH9@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_3232569_5	1408433.JHXV01000006_gene2690	3.239e-48	196.0	COG1287@1|root,COG1287@2|Bacteria,4NUWQ@976|Bacteroidetes	976|Bacteroidetes	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3232569_6	443144.GM21_1658	1.757e-44	181.0	2DNVT@1|root,32ZDR@2|Bacteria,1QWIA@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3233400_2	886379.AEWI01000052_gene2662	3.511e-83	284.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,2FNDJ@200643|Bacteroidia,3XJAB@558415|Marinilabiliaceae	976|Bacteroidetes	E	Glutamine amidotransferase domain	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS3_k127_3233400_3	1123234.AUKI01000014_gene2451	1.799e-80	282.0	COG0438@1|root,COG0438@2|Bacteria,4NMHA@976|Bacteroidetes,1IIKP@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
TLS3_k127_3233400_4	1250005.PHEL85_1405	2.233e-67	235.0	COG0110@1|root,COG0110@2|Bacteria,4NMZ2@976|Bacteroidetes,1I1H0@117743|Flavobacteriia,3VXD4@52959|Polaribacter	976|Bacteroidetes	S	acetyltransferase, isoleucine patch superfamily	wcaF	-	-	ko:K03818	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
TLS3_k127_3233400_0	743722.Sph21_2995	4.696e-312	970.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1IQ2F@117747|Sphingobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
TLS3_k127_3233400_6	1216967.L100_00920	9.297e-15	82.0	COG2890@1|root,COG2890@2|Bacteria,4NYKK@976|Bacteroidetes,1IBX2@117743|Flavobacteriia,34QUA@308865|Elizabethkingia	976|Bacteroidetes	H	protein-(glutamine-N5) methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3233400_1	694427.Palpr_2054	4.139e-120	396.0	COG0758@1|root,COG1948@1|root,COG0758@2|Bacteria,COG1948@2|Bacteria,4NF7T@976|Bacteroidetes,2FKYE@200643|Bacteroidia,22WZ4@171551|Porphyromonadaceae	976|Bacteroidetes	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
TLS3_k127_3233400_5	755732.Fluta_2911	1.701e-45	178.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,1I5TM@117743|Flavobacteriia,2PBI1@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
TLS3_k127_3312811_0	1121373.KB903641_gene3706	1.812e-30	138.0	2C4MF@1|root,300D5@2|Bacteria,4NPEA@976|Bacteroidetes,47RYT@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3312811_2	269798.CHU_2285	5.673e-13	81.0	COG2067@1|root,COG2067@2|Bacteria,4NG4A@976|Bacteroidetes,47V9Y@768503|Cytophagia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3312811_1	1408433.JHXV01000005_gene2520	2.584e-28	119.0	COG1520@1|root,COG1520@2|Bacteria,4PBXV@976|Bacteroidetes,1ICQN@117743|Flavobacteriia,2PBSC@246874|Cryomorphaceae	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3319126_0	153721.MYP_2527	3.364e-60	229.0	COG0457@1|root,COG0457@2|Bacteria,4NJEF@976|Bacteroidetes,47Q7U@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_16,TPR_2,TPR_8
TLS3_k127_3319126_1	746697.Aeqsu_1386	2.508e-22	98.0	COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,1HXV8@117743|Flavobacteriia	976|Bacteroidetes	S	amidohydrolase	yafV	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
TLS3_k127_3325888_2	411901.BACCAC_00941	2.293e-34	150.0	COG1388@1|root,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,2FNR1@200643|Bacteroidia,4AKK3@815|Bacteroidaceae	976|Bacteroidetes	M	LysM domain	lysM	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
TLS3_k127_3325888_0	755732.Fluta_2924	1.707e-261	813.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,1HX9A@117743|Flavobacteriia,2PAFZ@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
TLS3_k127_3325888_3	743722.Sph21_4631	4.446e-05	49.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IPXM@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Resolvase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TLS3_k127_3325888_1	153721.MYP_3668	1.386e-204	655.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47ME1@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS3_k127_3352001_0	755732.Fluta_3106	6.846e-138	461.0	COG3291@1|root,COG3291@2|Bacteria,4PI0I@976|Bacteroidetes,1I5WG@117743|Flavobacteriia,2PBH4@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_335305_0	1392490.JHZX01000001_gene2879	7.723e-61	212.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,1I4BI@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_335305_1	593750.Metfor_2801	2.341e-27	116.0	arCOG02349@1|root,arCOG02350@1|root,arCOG02349@2157|Archaea,arCOG02350@2157|Archaea,2Y7NM@28890|Euryarchaeota,2NBKN@224756|Methanomicrobia	224756|Methanomicrobia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,MEDS,PAS_3,PAS_4,PAS_9
TLS3_k127_3378615_3	1313421.JHBV01000016_gene5580	9.524e-37	148.0	COG1262@1|root,COG1262@2|Bacteria,4NRGU@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TLS3_k127_3378615_1	330214.NIDE0478	2.483e-75	258.0	COG0588@1|root,COG0588@2|Bacteria,3J118@40117|Nitrospirae	40117|Nitrospirae	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
TLS3_k127_3378615_2	1233950.IW22_13950	7.143e-61	213.0	COG0561@1|root,COG0561@2|Bacteria,4PKY8@976|Bacteroidetes,1I1C5@117743|Flavobacteriia,3ZNHK@59732|Chryseobacterium	976|Bacteroidetes	S	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3378615_0	1035193.HMPREF9073_02590	1.149e-120	391.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,1HXCX@117743|Flavobacteriia,1ER0Y@1016|Capnocytophaga	976|Bacteroidetes	E	aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
TLS3_k127_3378615_4	1538644.KO02_20550	3.835e-07	57.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,1IPS5@117747|Sphingobacteriia	976|Bacteroidetes	S	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_33809_3	1453500.AT05_11620	1.991e-83	286.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,1HY1X@117743|Flavobacteriia	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_33809_5	929556.Solca_3365	4.612e-40	156.0	COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,1IRVN@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome C	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
TLS3_k127_33809_4	1218108.KB908295_gene1811	1.067e-56	203.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1HXN6@117743|Flavobacteriia	976|Bacteroidetes	C	membrane	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
TLS3_k127_33809_1	1347342.BN863_2230	6.826e-227	709.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia	976|Bacteroidetes	C	Polysulphide reductase	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
TLS3_k127_33809_0	926549.KI421517_gene1908	9.103e-297	945.0	COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,47NK7@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S dicluster domain	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
TLS3_k127_33809_2	1046627.BZARG_1928	2.003e-96	331.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,1HXD9@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
TLS3_k127_33809_7	1408433.JHXV01000015_gene1745	3.686e-28	119.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Antigen_C,DUF4150,PorP_SprF
TLS3_k127_3384734_0	1249975.JQLP01000005_gene1923	2.824e-123	404.0	COG3547@1|root,COG3547@2|Bacteria,4NIKY@976|Bacteroidetes,1HZCU@117743|Flavobacteriia,2P762@244698|Gillisia	976|Bacteroidetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
TLS3_k127_3390729_0	153721.MYP_4929	7.383e-78	260.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,47M06@768503|Cytophagia	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
TLS3_k127_3390729_1	1453500.AT05_04470	5.559e-20	105.0	2EW37@1|root,33PGF@2|Bacteria,4P22D@976|Bacteroidetes,1I7PK@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3416473_2	313606.M23134_01293	3.163e-41	168.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47K1N@768503|Cytophagia	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
TLS3_k127_3416473_0	1121889.AUDM01000010_gene584	2.142e-86	302.0	COG3291@1|root,COG3291@2|Bacteria,4NM0P@976|Bacteroidetes,1I0CF@117743|Flavobacteriia,2P0BI@237|Flavobacterium	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M14
TLS3_k127_3416473_1	1453500.AT05_00910	4.517e-71	243.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,1HYNV@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
TLS3_k127_3449207_3	1189612.A33Q_3821	1.607e-19	87.0	COG0492@1|root,COG0492@2|Bacteria,4NEQM@976|Bacteroidetes,47KZW@768503|Cytophagia	976|Bacteroidetes	C	Ferredoxin--NADP reductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_3449207_1	1121889.AUDM01000013_gene1874	1.526e-54	216.0	COG4447@1|root,COG4447@2|Bacteria,4PM0K@976|Bacteroidetes,1I2DM@117743|Flavobacteriia,2NV0G@237|Flavobacterium	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
TLS3_k127_3449207_4	456442.Mboo_0818	1.578e-09	71.0	COG3291@1|root,arCOG02508@2157|Archaea,2XUY6@28890|Euryarchaeota,2NAFS@224756|Methanomicrobia	224756|Methanomicrobia	O	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
TLS3_k127_3449207_0	1168034.FH5T_03540	2.753e-98	330.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,2FN5I@200643|Bacteroidia	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
TLS3_k127_3449207_2	755732.Fluta_3589	6.005e-32	126.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,1I43K@117743|Flavobacteriia,2PB3N@246874|Cryomorphaceae	976|Bacteroidetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
TLS3_k127_3449207_5	517418.Ctha_1540	3.803e-06	60.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	1.1.3.9,3.2.1.4	ko:K01179,ko:K04618	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R01098,R06200,R11307,R11308	RC00194	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cadherin-like,DUF1929,F5_F8_type_C,Glyco_hydro_64,Kelch_6,PKD
TLS3_k127_3476169_0	761193.Runsl_3804	1.29e-09	70.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NS69@976|Bacteroidetes	976|Bacteroidetes	O	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_34766_5	1453500.AT05_05435	5.611e-42	158.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1HX5B@117743|Flavobacteriia	976|Bacteroidetes	C	Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
TLS3_k127_34766_3	1122621.ATZA01000026_gene2215	5.088e-60	214.0	COG1131@1|root,COG1131@2|Bacteria,4NN9G@976|Bacteroidetes,1IS33@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
TLS3_k127_34766_2	714943.Mucpa_2748	1.477e-95	319.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,1IQ6Z@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
TLS3_k127_34766_0	1270196.JCKI01000001_gene3810	1.324e-191	609.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1IQB1@117747|Sphingobacteriia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
TLS3_k127_34766_4	1358423.N180_20790	4.794e-42	166.0	COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes	976|Bacteroidetes	L	DNA uptake protein and related DNA-binding	comEA	-	-	-	-	-	-	-	-	-	-	-	HHH_3
TLS3_k127_34766_1	1123277.KB893172_gene461	1.384e-167	540.0	COG0531@1|root,COG0531@2|Bacteria,4NH7J@976|Bacteroidetes,47KCV@768503|Cytophagia	976|Bacteroidetes	E	PFAM amino acid permease-associated region	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
TLS3_k127_34766_6	755732.Fluta_2422	1.13e-17	90.0	29BEQ@1|root,2ZYD2@2|Bacteria,4PD0R@976|Bacteroidetes,1ICRX@117743|Flavobacteriia,2PBXT@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_34766_9	926562.Oweho_2323	0.0009183	48.0	COG1524@1|root,COG1524@2|Bacteria,4PIF1@976|Bacteroidetes,1IGD1@117743|Flavobacteriia,2PBDT@246874|Cryomorphaceae	976|Bacteroidetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
TLS3_k127_34766_7	515635.Dtur_1285	5.149e-13	81.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_M8,Peptidase_S8,SLH
TLS3_k127_348145_9	1506583.JQJY01000003_gene3732	1.821e-54	196.0	COG1670@1|root,COG1670@2|Bacteria,4NQEC@976|Bacteroidetes,1I3F6@117743|Flavobacteriia,2NU1Y@237|Flavobacterium	976|Bacteroidetes	J	GNAT family acetyltransferase	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
TLS3_k127_348145_11	518766.Rmar_0815	3.309e-36	141.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,1FJEF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Endoribonuclease L-PSP	yjgF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
TLS3_k127_348145_2	761193.Runsl_4309	1.891e-169	542.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,47KCX@768503|Cytophagia	976|Bacteroidetes	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
TLS3_k127_348145_5	762903.Pedsa_1962	1.784e-101	336.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,1INN2@117747|Sphingobacteriia	976|Bacteroidetes	NU	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_348145_1	1453505.JASY01000001_gene3674	1.834e-208	662.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1HZCT@117743|Flavobacteriia,2NTX8@237|Flavobacterium	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
TLS3_k127_348145_15	1408433.JHXV01000001_gene1086	3.924e-17	95.0	28ZU6@1|root,2ZMIV@2|Bacteria,4P83G@976|Bacteroidetes,1IMR8@117743|Flavobacteriia,2PBNF@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_348145_16	398720.MED217_07806	1.812e-16	89.0	COG0823@1|root,COG0823@2|Bacteria,4NITC@976|Bacteroidetes,1IJFZ@117743|Flavobacteriia,2XJ7V@283735|Leeuwenhoekiella	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_348145_12	1202532.FF52_06130	7.18e-30	125.0	COG0671@1|root,COG0671@2|Bacteria,4NNVQ@976|Bacteroidetes,1ID2Y@117743|Flavobacteriia,2NX3X@237|Flavobacterium	976|Bacteroidetes	I	Acid phosphatase homologues	ybjG	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
TLS3_k127_348145_6	1278073.MYSTI_00938	2.152e-75	254.0	COG0251@1|root,COG0251@2|Bacteria,1MYEM@1224|Proteobacteria,438KW@68525|delta/epsilon subdivisions,2X3V9@28221|Deltaproteobacteria,2YX7P@29|Myxococcales	28221|Deltaproteobacteria	J	Endoribonuclease L-PSP	-	-	3.5.99.5	ko:K15067	ko00380,map00380	-	R03887	RC01015	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
TLS3_k127_348145_13	926562.Oweho_1286	9.467e-26	117.0	COG0589@1|root,COG0589@2|Bacteria,4PICR@976|Bacteroidetes,1I8WQ@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_348145_0	929556.Solca_3313	0.0	1375.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1IPPT@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
TLS3_k127_348145_10	755732.Fluta_1722	9.603e-41	164.0	COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,1I1Y4@117743|Flavobacteriia,2PAZZ@246874|Cryomorphaceae	976|Bacteroidetes	T	Molecular chaperone DnaK	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
TLS3_k127_348145_8	929713.NIASO_16800	1.871e-60	216.0	COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,1IQPW@117747|Sphingobacteriia	976|Bacteroidetes	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
TLS3_k127_348145_4	945713.IALB_3004	1.312e-115	381.0	COG0276@1|root,COG0276@2|Bacteria	2|Bacteria	H	ferrochelatase activity	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
TLS3_k127_348145_7	555500.I215_00795	8.573e-66	233.0	COG2267@1|root,COG2267@2|Bacteria,4NHA9@976|Bacteroidetes,1HY0U@117743|Flavobacteriia	976|Bacteroidetes	I	Alpha beta hydrolase	yfbB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_348145_14	391596.PBAL39_04808	1.621e-18	87.0	COG1918@1|root,COG1918@2|Bacteria,4P9Q5@976|Bacteroidetes,1ITZ3@117747|Sphingobacteriia	976|Bacteroidetes	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
TLS3_k127_348145_3	1454007.JAUG01000050_gene1891	2.525e-151	497.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,1IPAK@117747|Sphingobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
TLS3_k127_3496313_5	869213.JCM21142_72772	1.028e-50	183.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,47RHF@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
TLS3_k127_3496313_4	755732.Fluta_2263	2.091e-56	202.0	2AAU0@1|root,3106Q@2|Bacteria,4NNSV@976|Bacteroidetes,1ICQH@117743|Flavobacteriia,2PBRJ@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3496313_0	1121904.ARBP01000006_gene4035	1.019e-170	574.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NHSC@976|Bacteroidetes,47XEJ@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Reg_prop,SpoIIE,Y_Y_Y
TLS3_k127_3496313_2	643867.Ftrac_2281	5.852e-141	470.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47U3Q@768503|Cytophagia	976|Bacteroidetes	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS3_k127_3496313_3	1122605.KB893647_gene420	1.421e-108	364.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_3496313_1	468059.AUHA01000003_gene1428	6.764e-170	551.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,1IP6H@117747|Sphingobacteriia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
TLS3_k127_3496313_6	555500.I215_11629	8.062e-40	157.0	COG0801@1|root,COG1428@1|root,COG0801@2|Bacteria,COG1428@2|Bacteria,4NGE8@976|Bacteroidetes,1HWTH@117743|Flavobacteriia	976|Bacteroidetes	FH	Pfam 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
TLS3_k127_3570508_2	1121889.AUDM01000022_gene508	5.705e-129	423.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,1HWY6@117743|Flavobacteriia,2NSIQ@237|Flavobacterium	976|Bacteroidetes	S	flavoprotein	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
TLS3_k127_3570508_1	1279009.ADICEAN_04130	9.601e-151	503.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia	976|Bacteroidetes	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
TLS3_k127_3570508_0	1121104.AQXH01000007_gene487	8.484e-278	861.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1IQEH@117747|Sphingobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
TLS3_k127_3570508_3	1453500.AT05_04480	1.503e-31	126.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,fn3
TLS3_k127_3575413_5	269798.CHU_2868	1.336e-108	358.0	COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,47PGN@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
TLS3_k127_3575413_7	269798.CHU_1056	1.605e-79	271.0	COG1853@1|root,COG1853@2|Bacteria,4NG6I@976|Bacteroidetes,47PFI@768503|Cytophagia	976|Bacteroidetes	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
TLS3_k127_3575413_3	1239962.C943_04413	5.081e-180	568.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,47KXJ@768503|Cytophagia	976|Bacteroidetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
TLS3_k127_3575413_1	929562.Emtol_2382	4.172e-307	950.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,47KM5@768503|Cytophagia	976|Bacteroidetes	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
TLS3_k127_3575413_0	1121904.ARBP01000004_gene790	5.226e-320	986.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,4NG9R@976|Bacteroidetes,47KDW@768503|Cytophagia	976|Bacteroidetes	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.3.1.1	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
TLS3_k127_3575413_13	1484460.JSWG01000009_gene360	1.185e-09	64.0	2DE0G@1|root,32U2C@2|Bacteria,4NTKN@976|Bacteroidetes,1I4D6@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3575413_6	1047013.AQSP01000144_gene895	1.825e-107	364.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
TLS3_k127_3575413_12	886293.Sinac_7569	2.426e-24	118.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase
TLS3_k127_3575413_14	984262.SGRA_0890	0.0001537	54.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
TLS3_k127_3575413_8	391596.PBAL39_18539	3.788e-68	243.0	2CEP6@1|root,314NU@2|Bacteria,4NQE8@976|Bacteroidetes,1IWN8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
TLS3_k127_3575413_10	1121897.AUGO01000009_gene2966	2.757e-49	178.0	COG0662@1|root,COG0662@2|Bacteria,4NS6V@976|Bacteroidetes,1I30K@117743|Flavobacteriia,2NX8A@237|Flavobacterium	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_3575413_2	468059.AUHA01000002_gene26	1.386e-260	825.0	COG0072@1|root,COG0072@2|Bacteria,4NF5B@976|Bacteroidetes,1IPW0@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
TLS3_k127_3575413_4	1313421.JHBV01000043_gene3177	6.734e-112	372.0	COG1804@1|root,COG1804@2|Bacteria,4NEA8@976|Bacteroidetes,1IQ7F@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
TLS3_k127_3575413_11	1265503.KB905161_gene3198	2.602e-28	119.0	COG0454@1|root,COG0456@2|Bacteria,1R407@1224|Proteobacteria,1RPJ2@1236|Gammaproteobacteria,2Q5NJ@267889|Colwelliaceae	1236|Gammaproteobacteria	K	Putative thioesterase (yiiD_Cterm)	yiiD	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,YiiD_C
TLS3_k127_3575413_9	755732.Fluta_0829	1.411e-52	208.0	COG5305@1|root,COG5305@2|Bacteria,4PAK3@976|Bacteroidetes,1IMPV@117743|Flavobacteriia,2PAU3@246874|Cryomorphaceae	976|Bacteroidetes	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_3595758_0	755732.Fluta_2725	1.206e-58	234.0	COG3210@1|root,COG3291@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IKDY@117743|Flavobacteriia,2PC6N@246874|Cryomorphaceae	976|Bacteroidetes	U	SPTR Conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA,SprB
TLS3_k127_3595758_2	938709.AUSH02000073_gene1706	1.025e-28	136.0	COG1572@1|root,COG3210@1|root,COG3291@1|root,COG4935@1|root,COG5492@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,COG5492@2|Bacteria,4NDZQ@976|Bacteroidetes	976|Bacteroidetes	H	Gliding motility-associated C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,P_proprotein,SprB
TLS3_k127_3595758_1	1358423.N180_13870	7.303e-58	209.0	COG0670@1|root,COG0670@2|Bacteria,4NMEV@976|Bacteroidetes,1J0DB@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
TLS3_k127_3595758_3	929556.Solca_2952	1.853e-28	118.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,1INNN@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
TLS3_k127_3683623_3	1131812.JQMS01000001_gene1807	3.748e-66	234.0	2C6BU@1|root,32S87@2|Bacteria,4NRX1@976|Bacteroidetes,1I6S7@117743|Flavobacteriia,2NYWP@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3683623_5	926562.Oweho_0246	1.083e-05	51.0	COG3211@1|root,COG3211@2|Bacteria,4NZ53@976|Bacteroidetes,1IN2H@117743|Flavobacteriia,2PC64@246874|Cryomorphaceae	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
TLS3_k127_3683623_1	402612.FP1689	2.425e-153	491.0	2CB8G@1|root,2Z88H@2|Bacteria,4NF68@976|Bacteroidetes,1HYYV@117743|Flavobacteriia,2NSPI@237|Flavobacterium	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
TLS3_k127_3683623_0	1341181.FLJC2902T_05490	4.627e-272	850.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,1HX75@117743|Flavobacteriia,2NTDV@237|Flavobacterium	976|Bacteroidetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
TLS3_k127_3683623_2	1250278.JQNQ01000001_gene2984	1.301e-100	332.0	COG0745@1|root,COG0745@2|Bacteria,4NIQC@976|Bacteroidetes,1HZUW@117743|Flavobacteriia	976|Bacteroidetes	T	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_3683623_4	1131812.JQMS01000001_gene2141	5.864e-41	154.0	COG0642@1|root,COG2205@2|Bacteria,4NFYN@976|Bacteroidetes,1HZ6X@117743|Flavobacteriia,2P05M@237|Flavobacterium	976|Bacteroidetes	T	Domain of unknown function (DUF4118)	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
TLS3_k127_3822530_2	1200567.JNKD01000002_gene2262	1.177e-17	93.0	COG0366@1|root,COG3291@1|root,COG0366@2|Bacteria,COG3291@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,1Y3Q3@135624|Aeromonadales	135624|Aeromonadales	G	Alpha-amylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM26,PKD
TLS3_k127_3822530_3	1380354.JIAN01000008_gene3362	7.036e-16	92.0	COG3291@1|root,COG3420@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,2GN7G@201174|Actinobacteria	201174|Actinobacteria	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_3,Malectin,PKD
TLS3_k127_3822530_5	1313421.JHBV01000041_gene3542	0.0001153	55.0	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes	976|Bacteroidetes	DZ	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3822530_0	929556.Solca_1282	1.76e-236	738.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1IPJK@117747|Sphingobacteriia	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
TLS3_k127_3822530_1	1380600.AUYN01000007_gene3241	7.947e-44	167.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,1HWXQ@117743|Flavobacteriia	976|Bacteroidetes	L	COG3893 Inactivated superfamily I helicase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
TLS3_k127_385706_1	1121904.ARBP01000003_gene6548	5.729e-80	276.0	COG0324@1|root,COG0324@2|Bacteria,4NFJY@976|Bacteroidetes,47MNF@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA2	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
TLS3_k127_385706_0	714943.Mucpa_4960	3.162e-243	760.0	COG0069@1|root,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,1IREF@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the glutamate synthase family	glt	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
TLS3_k127_385706_2	153721.MYP_2914	4.255e-22	102.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4P1P3@976|Bacteroidetes,47THG@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
TLS3_k127_3857918_1	929704.Myrod_2060	1.872e-72	248.0	COG0744@1|root,COG0744@2|Bacteria,4NF90@976|Bacteroidetes,1HXMN@117743|Flavobacteriia,47HS8@76831|Myroides	976|Bacteroidetes	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
TLS3_k127_3857918_2	487796.Flav2ADRAFT_0193	4.133e-15	82.0	COG0526@1|root,COG0526@2|Bacteria,4NS1W@976|Bacteroidetes,1I3EA@117743|Flavobacteriia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
TLS3_k127_3857918_0	1270193.JARP01000001_gene2597	0.0	1196.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,1HXI7@117743|Flavobacteriia,2NUFG@237|Flavobacterium	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
TLS3_k127_3857918_3	404380.Gbem_4124	2.193e-14	78.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_5
TLS3_k127_3888634_0	869213.JCM21142_3846	1.772e-70	257.0	COG1729@1|root,COG2885@1|root,COG1729@2|Bacteria,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K01999,ko:K08309	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko01000,ko01011,ko02000	3.A.1.4	GH23	-	Beta-lactamase,OmpA,PD40,SLT,TPR_2,TPR_6,TPR_8
TLS3_k127_3888634_2	269798.CHU_2605	1.217e-43	172.0	COG4772@1|root,COG4772@2|Bacteria,4P1I6@976|Bacteroidetes,47UDX@768503|Cytophagia	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_3888634_1	869213.JCM21142_3842	4.408e-53	211.0	COG3291@1|root,COG3291@2|Bacteria,4NPCA@976|Bacteroidetes,47S64@768503|Cytophagia	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_3926818_1	760192.Halhy_5161	1.218e-143	482.0	COG1629@1|root,COG1629@2|Bacteria,4NFW1@976|Bacteroidetes,1IQ77@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
TLS3_k127_3926818_2	760192.Halhy_5162	7.018e-97	327.0	COG2374@1|root,COG2374@2|Bacteria,4NEHG@976|Bacteroidetes,1IS63@117747|Sphingobacteriia	976|Bacteroidetes	S	Endonuclease exonuclease phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_3926818_0	714943.Mucpa_3278	0.0	1283.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,4NEDY@976|Bacteroidetes,1IQ2I@117747|Sphingobacteriia	976|Bacteroidetes	HJM	Belongs to the MurCDEF family	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,RimK
TLS3_k127_3932089_4	694427.Palpr_1792	4.791e-54	198.0	COG4123@1|root,COG4123@2|Bacteria,4NG1X@976|Bacteroidetes,2FMHH@200643|Bacteroidia,22Y0T@171551|Porphyromonadaceae	976|Bacteroidetes	J	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	smtA	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
TLS3_k127_3932089_6	1408433.JHXV01000014_gene3639	6.179e-39	158.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IFTS@117743|Flavobacteriia,2PBTH@246874|Cryomorphaceae	976|Bacteroidetes	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_3932089_7	1408433.JHXV01000014_gene3694	2.492e-38	168.0	COG3291@1|root,COG3291@2|Bacteria,4PI05@976|Bacteroidetes,1ICSF@117743|Flavobacteriia,2PBZU@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_3932089_8	485918.Cpin_2588	3.424e-09	72.0	COG3291@1|root,COG3291@2|Bacteria,4NNVK@976|Bacteroidetes,1ISKM@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
TLS3_k127_3932089_9	504472.Slin_3586	0.0001171	57.0	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Collagen_bind,DUF11,SdrD_B
TLS3_k127_3932089_2	1122176.KB903532_gene2579	7.187e-155	496.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,1IPSN@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
TLS3_k127_3932089_0	468059.AUHA01000005_gene2520	3.582e-195	619.0	COG0057@1|root,COG0057@2|Bacteria,4NG5C@976|Bacteroidetes,1IQW8@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA2	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
TLS3_k127_3932089_5	1122605.KB893626_gene2354	7.392e-48	176.0	2AN5I@1|root,31D3D@2|Bacteria,4NQTI@976|Bacteroidetes,1IUBS@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
TLS3_k127_3932089_3	755732.Fluta_2148	5.567e-58	206.0	COG0503@1|root,COG0503@2|Bacteria,4NP7K@976|Bacteroidetes,1I29Z@117743|Flavobacteriia,2PBP0@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
TLS3_k127_3932089_1	926562.Oweho_1486	3.996e-193	608.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1HWV4@117743|Flavobacteriia,2PAJV@246874|Cryomorphaceae	976|Bacteroidetes	C	Acyl-CoA dehydrogenase, N-terminal domain	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_394211_3	929556.Solca_3321	6.872e-52	201.0	COG4219@1|root,COG4219@2|Bacteria,4PKZS@976|Bacteroidetes,1IR4A@117747|Sphingobacteriia	976|Bacteroidetes	KT	Gliding motility-associated protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
TLS3_k127_394211_2	755732.Fluta_2289	1.413e-66	236.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,1HYV7@117743|Flavobacteriia,2PAW7@246874|Cryomorphaceae	976|Bacteroidetes	S	Gliding motility protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_394211_0	755732.Fluta_2288	2.479e-170	548.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1HXXN@117743|Flavobacteriia,2PAKH@246874|Cryomorphaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TLS3_k127_394211_4	1168034.FH5T_07295	8.668e-42	166.0	COG0226@1|root,COG0226@2|Bacteria,4PKGM@976|Bacteroidetes,2G3GH@200643|Bacteroidia	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_394211_5	1346330.M472_02015	2.185e-39	147.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes	976|Bacteroidetes	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
TLS3_k127_394211_1	755732.Fluta_2724	1.012e-75	260.0	COG1076@1|root,COG1076@2|Bacteria,4NF1B@976|Bacteroidetes,1HYUI@117743|Flavobacteriia,2PBZR@246874|Cryomorphaceae	976|Bacteroidetes	O	Tellurite resistance protein TerB	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
TLS3_k127_3950309_4	1313421.JHBV01000002_gene571	5.973e-10	69.0	2DS3S@1|root,33EDT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3950309_1	643867.Ftrac_3732	3.243e-136	446.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,47MT4@768503|Cytophagia	976|Bacteroidetes	E	Saccharopine dehydrogenase	-	-	1.5.1.10,1.5.1.7	ko:K00290,ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R02315	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
TLS3_k127_3950309_0	1121904.ARBP01000004_gene927	4.227e-213	688.0	COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
TLS3_k127_3950309_2	926562.Oweho_2456	2.112e-131	435.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,1HYXP@117743|Flavobacteriia,2PACQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Transglycosylase SLT domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
TLS3_k127_3950309_3	1358423.N180_16960	4.057e-58	210.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,1IQAP@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
TLS3_k127_3950309_5	929556.Solca_0671	9.787e-05	45.0	COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,1IT0E@117747|Sphingobacteriia	976|Bacteroidetes	U	Biopolymer transport protein ExbD TolR	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
TLS3_k127_3962863_2	1434325.AZQN01000005_gene3650	7.837e-10	69.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,47KTA@768503|Cytophagia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
TLS3_k127_3962863_4	153721.MYP_2405	0.0002934	48.0	2E7ZI@1|root,333DR@2|Bacteria,4NVT6@976|Bacteroidetes,47T5I@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3962863_3	1131730.BAVI_00750	6.804e-08	55.0	COG3708@1|root,COG3708@2|Bacteria,1VJT1@1239|Firmicutes,4HREN@91061|Bacilli,1ZRAV@1386|Bacillus	91061|Bacilli	K	Putative zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn_ribbon_2
TLS3_k127_3962863_1	755732.Fluta_1300	3.595e-157	506.0	COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,1HWNW@117743|Flavobacteriia,2PAA5@246874|Cryomorphaceae	976|Bacteroidetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS3_k127_3962863_0	714943.Mucpa_2531	0.0	1072.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1IQYB@117747|Sphingobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase, E1	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
TLS3_k127_396517_0	926562.Oweho_2196	1.453e-116	381.0	COG0260@1|root,COG0260@2|Bacteria,4NDWT@976|Bacteroidetes,1HZZ2@117743|Flavobacteriia,2PA9B@246874|Cryomorphaceae	976|Bacteroidetes	E	Cytosol aminopeptidase family, catalytic domain	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
TLS3_k127_396517_1	665571.STHERM_c19770	5.234e-57	213.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_396517_2	1045858.Bint_0072	1.102e-06	55.0	COG2333@1|root,COG2333@2|Bacteria	2|Bacteria	N	competence protein COMEC	-	-	-	ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Lactamase_B
TLS3_k127_400569_1	1223410.KN050846_gene203	4.421e-05	55.0	COG4447@1|root,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,1HYZP@117743|Flavobacteriia	976|Bacteroidetes	O	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
TLS3_k127_400569_0	1121904.ARBP01000003_gene6177	1.516e-23	101.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,47QER@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
TLS3_k127_400824_0	929556.Solca_1727	8.24e-206	652.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IQYT@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS3_k127_400824_2	1150600.ADIARSV_1895	5.448e-90	309.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IP8S@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
TLS3_k127_400824_1	1434325.AZQN01000010_gene3970	6.245e-96	330.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,47KE9@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_400824_4	929556.Solca_1724	9.322e-47	176.0	COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,1ISRH@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_400824_3	762903.Pedsa_2515	2.725e-59	216.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,1IT7G@117747|Sphingobacteriia	976|Bacteroidetes	M	peptidase M23	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_40105_2	1408433.JHXV01000027_gene3728	4.208e-158	533.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
TLS3_k127_40105_12	945713.IALB_0968	1.068e-15	92.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,Sel1,TPR_8,WG_beta_rep
TLS3_k127_40105_11	643473.KB235930_gene2545	7.139e-21	109.0	COG0457@1|root,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1HJ4A@1161|Nostocales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
TLS3_k127_40105_6	1313301.AUGC01000005_gene373	3.988e-61	234.0	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,4NGRJ@976|Bacteroidetes	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Cleaved_Adhesin,PKD,Peptidase_M43,fn3
TLS3_k127_40105_0	926562.Oweho_2105	1.929e-184	614.0	COG3291@1|root,COG3291@2|Bacteria,4PMDA@976|Bacteroidetes,1IKH7@117743|Flavobacteriia,2PC60@246874|Cryomorphaceae	976|Bacteroidetes	E	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
TLS3_k127_40105_15	1484460.JSWG01000015_gene859	5.864e-06	60.0	COG3291@1|root,COG4886@1|root,COG3291@2|Bacteria,COG4886@2|Bacteria,4NIM6@976|Bacteroidetes,1HX50@117743|Flavobacteriia	976|Bacteroidetes	M	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
TLS3_k127_40105_5	1380384.JADN01000006_gene2566	2.463e-62	222.0	COG0300@1|root,COG0300@2|Bacteria,4NEFB@976|Bacteroidetes,1HX0Q@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_40105_13	1239962.C943_02610	9.817e-12	73.0	28NMY@1|root,2ZBNE@2|Bacteria,4NN50@976|Bacteroidetes,47YAY@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_40105_3	929556.Solca_2578	4.886e-153	501.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,1IQA9@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
TLS3_k127_40105_1	926551.KB900709_gene1131	7.976e-180	567.0	COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,1HYMK@117743|Flavobacteriia,1EQHI@1016|Capnocytophaga	976|Bacteroidetes	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
TLS3_k127_40105_8	929556.Solca_3097	7.279e-41	155.0	COG2905@1|root,COG2905@2|Bacteria,4NP1Y@976|Bacteroidetes,1ISY1@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
TLS3_k127_40105_9	1408433.JHXV01000020_gene3501	1.278e-33	142.0	COG4372@1|root,COG4372@2|Bacteria,4PKE4@976|Bacteroidetes,1IKDW@117743|Flavobacteriia,2PBQB@246874|Cryomorphaceae	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_40105_7	585543.HMPREF0969_01903	1.857e-57	207.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,2FP14@200643|Bacteroidia,4AN3K@815|Bacteroidaceae	976|Bacteroidetes	S	ComF family	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
TLS3_k127_40105_10	906888.JCM19314_1252	1.668e-28	119.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,1I30U@117743|Flavobacteriia,3HKF2@363408|Nonlabens	976|Bacteroidetes	S	Protein of unknown function, DUF393	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
TLS3_k127_40105_14	365044.Pnap_4548	2.064e-11	76.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2WEY0@28216|Betaproteobacteria,4AJBU@80864|Comamonadaceae	28216|Betaproteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
TLS3_k127_40105_4	1408433.JHXV01000004_gene3388	1.106e-62	229.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,1I54C@117743|Flavobacteriia,2PAIC@246874|Cryomorphaceae	976|Bacteroidetes	Q	PFAM FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS3_k127_4013719_2	761193.Runsl_3333	5.69e-21	94.0	COG3620@1|root,COG3620@2|Bacteria,4NV6Z@976|Bacteroidetes,47RVV@768503|Cytophagia	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
TLS3_k127_4013719_1	761193.Runsl_3334	7.113e-54	190.0	COG3550@1|root,COG3550@2|Bacteria,4NTCR@976|Bacteroidetes,47S3B@768503|Cytophagia	976|Bacteroidetes	S	HipA N-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA
TLS3_k127_4013719_0	761193.Runsl_4265	2.714e-133	431.0	COG3550@1|root,COG3550@2|Bacteria,4NG6N@976|Bacteroidetes,47MIR@768503|Cytophagia	976|Bacteroidetes	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	HipA_C
TLS3_k127_401380_3	1158294.JOMI01000003_gene2239	1.158e-27	117.0	COG0526@1|root,COG0526@2|Bacteria,4NT67@976|Bacteroidetes,2FQHA@200643|Bacteroidia	976|Bacteroidetes	CO	AhpC Tsa family	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
TLS3_k127_401380_0	999419.HMPREF1077_01430	5.806e-137	440.0	COG0330@1|root,COG0330@2|Bacteria,4NH8V@976|Bacteroidetes,2FQPC@200643|Bacteroidia,22Z0Q@171551|Porphyromonadaceae	976|Bacteroidetes	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TLS3_k127_401380_2	411477.PARMER_02873	3.148e-47	172.0	COG1725@1|root,COG1725@2|Bacteria,4PKHR@976|Bacteroidetes,2G09Z@200643|Bacteroidia,2313V@171551|Porphyromonadaceae	976|Bacteroidetes	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_3
TLS3_k127_401380_1	1168034.FH5T_12035	8.536e-66	226.0	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,2FVX6@200643|Bacteroidia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
TLS3_k127_4054440_4	1408433.JHXV01000029_gene3118	8.332e-26	115.0	COG3637@1|root,COG3637@2|Bacteria,4NQ11@976|Bacteroidetes	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_4054440_1	1131812.JQMS01000001_gene428	5.418e-127	419.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,1HX3M@117743|Flavobacteriia,2NTAD@237|Flavobacterium	976|Bacteroidetes	M	Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
TLS3_k127_4054440_2	929703.KE386491_gene2810	4.439e-102	336.0	COG1136@1|root,COG1136@2|Bacteria,4NFCG@976|Bacteroidetes,47KXC@768503|Cytophagia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	-	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
TLS3_k127_4054440_0	1123057.P872_01265	2.376e-171	547.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,47MB4@768503|Cytophagia	976|Bacteroidetes	M	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
TLS3_k127_4054440_3	925409.KI911562_gene1769	1.19e-68	239.0	COG0845@1|root,COG0845@2|Bacteria,4NITE@976|Bacteroidetes,1ISHH@117747|Sphingobacteriia	976|Bacteroidetes	M	SPTR Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,HlyD_D23
TLS3_k127_407406_13	929703.KE386491_gene3476	9.977e-38	143.0	COG0407@1|root,COG0407@2|Bacteria,4NEQ7@976|Bacteroidetes,47K90@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
TLS3_k127_407406_3	755732.Fluta_3918	2.66e-131	443.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,1HYK9@117743|Flavobacteriia,2PBD2@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Peptidase family M1	pepN1	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
TLS3_k127_407406_17	762903.Pedsa_3145	9.126e-26	108.0	COG2827@1|root,COG2827@2|Bacteria,4NUN3@976|Bacteroidetes,1IUCP@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Excinuclease ABC, C subunit	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
TLS3_k127_407406_7	468059.AUHA01000005_gene2510	2.412e-80	301.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1IPPI@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,Reg_prop,Y_Y_Y
TLS3_k127_407406_10	1453498.LG45_07295	1.582e-55	203.0	COG3279@1|root,COG3279@2|Bacteria,4NNHE@976|Bacteroidetes,1I3FD@117743|Flavobacteriia,2P0EI@237|Flavobacterium	976|Bacteroidetes	T	LytTR family two component system response regulatory protein	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_407406_5	1313421.JHBV01000028_gene1857	4.456e-120	433.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
TLS3_k127_407406_14	755732.Fluta_2399	7.568e-34	153.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_407406_1	1313421.JHBV01000028_gene1857	5.507e-151	527.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
TLS3_k127_407406_16	700598.Niako_3021	1.728e-28	135.0	COG3291@1|root,COG3291@2|Bacteria,4NRDH@976|Bacteroidetes,1IWXM@117747|Sphingobacteriia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_407406_2	1313421.JHBV01000028_gene1857	2.193e-136	482.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
TLS3_k127_407406_15	755732.Fluta_2399	1.488e-32	149.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_407406_11	1408433.JHXV01000014_gene3639	8.733e-46	179.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IFTS@117743|Flavobacteriia,2PBTH@246874|Cryomorphaceae	976|Bacteroidetes	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_407406_19	1313421.JHBV01000049_gene57	7.8e-18	98.0	COG2133@1|root,COG3209@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,CHU_C,Copper-bind,DUF1080,GSDH,PKD,SprB
TLS3_k127_407406_4	204669.Acid345_0764	9.209e-130	441.0	COG2706@1|root,COG5492@1|root,COG2706@2|Bacteria,COG5492@2|Bacteria,3Y6M8@57723|Acidobacteria,2JMGX@204432|Acidobacteriia	204432|Acidobacteriia	GN	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4
TLS3_k127_407406_20	1121899.Q764_05805	5.417e-05	53.0	COG3291@1|root,COG3291@2|Bacteria,4NG09@976|Bacteroidetes,1HY3Z@117743|Flavobacteriia,2NU61@237|Flavobacterium	976|Bacteroidetes	O	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
TLS3_k127_407406_6	1434325.AZQN01000010_gene3939	1.249e-108	355.0	COG0580@1|root,COG0580@2|Bacteria,4NFW4@976|Bacteroidetes,47RZK@768503|Cytophagia	976|Bacteroidetes	U	Belongs to the MIP aquaporin (TC 1.A.8) family	aqpZ	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
TLS3_k127_407406_18	631362.Thi970DRAFT_02568	1.942e-19	96.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16,Methyltransf_23,Methyltransf_25
TLS3_k127_407406_0	755732.Fluta_1802	2.44e-250	793.0	COG0475@1|root,COG0490@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,4NGF6@976|Bacteroidetes,1HXGN@117743|Flavobacteriia,2PBVT@246874|Cryomorphaceae	976|Bacteroidetes	P	Sodium hydrogen exchanger family	nhaA	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C
TLS3_k127_407406_9	1121899.Q764_05120	1.121e-56	204.0	COG0500@1|root,COG2226@2|Bacteria,4PM4H@976|Bacteroidetes,1IJJ7@117743|Flavobacteriia	976|Bacteroidetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_407406_8	1239962.C943_04102	5.931e-65	228.0	COG4430@1|root,COG4430@2|Bacteria,4NN4Z@976|Bacteroidetes,47PX0@768503|Cytophagia	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
TLS3_k127_407406_12	1279009.ADICEAN_01812	7.415e-40	154.0	COG1670@1|root,COG1670@2|Bacteria,4NNZZ@976|Bacteroidetes,47QMT@768503|Cytophagia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TLS3_k127_409907_2	649349.Lbys_0975	1.168e-116	380.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,47KYB@768503|Cytophagia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_409907_0	649349.Lbys_0973	8.82e-240	748.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,47KD4@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
TLS3_k127_409907_7	742767.HMPREF9456_02183	3.221e-15	81.0	COG0607@1|root,COG0607@2|Bacteria,4NVA1@976|Bacteroidetes,2G2WY@200643|Bacteroidia,231YX@171551|Porphyromonadaceae	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS3_k127_409907_4	153721.MYP_4368	1.884e-91	303.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,47NY1@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
TLS3_k127_409907_5	649349.Lbys_0966	2.371e-77	261.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,47P92@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
TLS3_k127_409907_1	760192.Halhy_2537	4.663e-124	407.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,1IRZ3@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
TLS3_k127_409907_6	1453500.AT05_06865	6.218e-36	141.0	COG1416@1|root,COG1416@2|Bacteria,4NUNC@976|Bacteroidetes,1I4Q6@117743|Flavobacteriia	976|Bacteroidetes	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
TLS3_k127_409907_3	1123248.KB893324_gene1688	9.568e-116	387.0	28JFD@1|root,2Z99B@2|Bacteria,4NFQJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OprD
TLS3_k127_41007_10	929556.Solca_4250	1.444e-63	224.0	COG0491@1|root,COG0491@2|Bacteria,4NINV@976|Bacteroidetes,1IS2X@117747|Sphingobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_41007_8	1168034.FH5T_20455	3.633e-76	267.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes	976|Bacteroidetes	E	fad dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
TLS3_k127_41007_14	1123277.KB893243_gene238	1.181e-28	120.0	COG4067@1|root,COG4067@2|Bacteria,4NS86@976|Bacteroidetes,47RH0@768503|Cytophagia	976|Bacteroidetes	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
TLS3_k127_41007_1	1121011.AUCB01000006_gene998	3.394e-124	405.0	COG0189@1|root,COG0189@2|Bacteria,4NED4@976|Bacteroidetes,1HZ04@117743|Flavobacteriia,23I6Q@178469|Arenibacter	976|Bacteroidetes	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
TLS3_k127_41007_5	1121904.ARBP01000002_gene7256	4.479e-94	317.0	COG3608@1|root,COG3608@2|Bacteria,4NE8S@976|Bacteroidetes,47KAM@768503|Cytophagia	976|Bacteroidetes	S	PFAM Succinylglutamate desuccinylase Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
TLS3_k127_41007_17	485917.Phep_3837	8.507e-15	76.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1IZBA@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
TLS3_k127_41007_2	1408433.JHXV01000005_gene2276	1.239e-107	354.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,1HWSP@117743|Flavobacteriia,2PA74@246874|Cryomorphaceae	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
TLS3_k127_41007_7	762984.HMPREF9445_03244	3.366e-88	303.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,2FN2X@200643|Bacteroidia,4AMFE@815|Bacteroidaceae	976|Bacteroidetes	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
TLS3_k127_41007_12	869213.JCM21142_72882	1.294e-38	152.0	2CI1G@1|root,2Z7JA@2|Bacteria,4NF1T@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4294
TLS3_k127_41007_0	929556.Solca_0687	5.94e-224	703.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1J0YT@117747|Sphingobacteriia	976|Bacteroidetes	I	Biotin carboxylase C-terminal domain	accC	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
TLS3_k127_41007_13	714943.Mucpa_4498	1.233e-37	151.0	COG1434@1|root,COG1434@2|Bacteria,4NNYV@976|Bacteroidetes,1ITFE@117747|Sphingobacteriia	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
TLS3_k127_41007_4	929556.Solca_2251	5.872e-95	326.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1INN1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
TLS3_k127_41007_15	153721.MYP_506	9.011e-18	85.0	COG1983@1|root,COG1983@2|Bacteria,4NUNU@976|Bacteroidetes,47RWN@768503|Cytophagia	976|Bacteroidetes	KT	PFAM PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
TLS3_k127_41007_18	329726.AM1_3891	1.873e-11	69.0	COG4249@1|root,COG4249@2|Bacteria,1GHQ3@1117|Cyanobacteria	1117|Cyanobacteria	S	Agenet domain	-	-	-	-	-	-	-	-	-	-	-	-	Agenet
TLS3_k127_41007_11	1408473.JHXO01000001_gene2447	2.828e-49	177.0	COG0599@1|root,COG0599@2|Bacteria,4NNRB@976|Bacteroidetes,2FTME@200643|Bacteroidia	976|Bacteroidetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
TLS3_k127_41007_9	946077.W5A_05813	6.735e-74	258.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1HYNB@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
TLS3_k127_41007_3	1249975.JQLP01000005_gene1242	5.909e-100	340.0	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,1HWZ7@117743|Flavobacteriia,2P7CQ@244698|Gillisia	976|Bacteroidetes	E	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
TLS3_k127_41007_6	1492737.FEM08_21300	4.947e-89	305.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,1HXKN@117743|Flavobacteriia,2NS7W@237|Flavobacterium	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
TLS3_k127_41007_16	494419.ALPM01000041_gene2547	2.461e-15	76.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,1W7ZW@1268|Micrococcaceae	201174|Actinobacteria	EH	Anthranilate synthase	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
TLS3_k127_410440_2	686340.Metal_1479	3.335e-39	148.0	COG1538@1|root,COG1538@2|Bacteria,1R3RV@1224|Proteobacteria,1SX2J@1236|Gammaproteobacteria,1XDYS@135618|Methylococcales	135618|Methylococcales	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_410440_0	929556.Solca_1830	4.263e-157	506.0	COG1253@1|root,COG1253@2|Bacteria,4NE9R@976|Bacteroidetes,1IP76@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	corC_1	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
TLS3_k127_410440_1	216432.CA2559_08381	3.775e-118	386.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,1HWPZ@117743|Flavobacteriia	976|Bacteroidetes	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
TLS3_k127_4105219_2	888059.HMPREF9071_0963	1.247e-42	160.0	COG1705@1|root,COG1705@2|Bacteria,4NEER@976|Bacteroidetes,1HYCP@117743|Flavobacteriia,1EQHC@1016|Capnocytophaga	976|Bacteroidetes	NU	Mannosyl-glycoprotein	lytG	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,LysM
TLS3_k127_4105219_1	1235803.C825_02364	3.976e-102	345.0	COG1672@1|root,COG1672@2|Bacteria,4NGM3@976|Bacteroidetes,2FM92@200643|Bacteroidia,22WF5@171551|Porphyromonadaceae	976|Bacteroidetes	S	Pfam:Arch_ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_2
TLS3_k127_4105219_3	525257.HMPREF0204_13191	4.091e-35	147.0	2DTEI@1|root,33K0Q@2|Bacteria,4NYHU@976|Bacteroidetes,1I72H@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4105219_4	1123269.NX02_04740	2.198e-17	92.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2U7C4@28211|Alphaproteobacteria,2K3YC@204457|Sphingomonadales	204457|Sphingomonadales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
TLS3_k127_4105219_5	926562.Oweho_1718	1.207e-15	79.0	COG3668@1|root,COG3668@2|Bacteria,4NXQF@976|Bacteroidetes,1IM9B@117743|Flavobacteriia,2PC2M@246874|Cryomorphaceae	976|Bacteroidetes	S	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4105219_0	926549.KI421517_gene119	4.355e-116	381.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,47M0A@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
TLS3_k127_4160380_5	1237149.C900_00122	2.782e-54	197.0	COG2353@1|root,COG2353@2|Bacteria,4NNMD@976|Bacteroidetes,47Q3B@768503|Cytophagia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_4160380_8	1519464.HY22_14020	3.818e-40	154.0	COG1846@1|root,COG1846@2|Bacteria,1FFDA@1090|Chlorobi	1090|Chlorobi	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
TLS3_k127_4160380_4	385682.AFSL01000024_gene2069	2.668e-70	259.0	2CMNP@1|root,32SF6@2|Bacteria,4NSZE@976|Bacteroidetes,2G31M@200643|Bacteroidia,3XIU2@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4160380_7	936136.ARRT01000006_gene2231	5.452e-41	161.0	COG2520@1|root,COG2520@2|Bacteria,1PJK4@1224|Proteobacteria,2VB8G@28211|Alphaproteobacteria,4BHI1@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
TLS3_k127_4160380_3	886379.AEWI01000012_gene1044	2.585e-70	246.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_4160380_9	1189619.pgond44_00475	5.909e-23	100.0	2AMWM@1|root,31CTE@2|Bacteria,4PBSF@976|Bacteroidetes,1IGUI@117743|Flavobacteriia,4C4H0@83612|Psychroflexus	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4160380_6	1121373.KB903632_gene458	1.337e-46	171.0	COG1848@1|root,COG1848@2|Bacteria,4NNGQ@976|Bacteroidetes,47STD@768503|Cytophagia	976|Bacteroidetes	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_3
TLS3_k127_4160380_2	1122176.KB903536_gene1761	9.871e-71	245.0	28KN2@1|root,2ZA6D@2|Bacteria,4NG7P@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4160380_1	1122176.KB903536_gene1761	2.851e-98	331.0	28KN2@1|root,2ZA6D@2|Bacteria,4NG7P@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4160380_0	385682.AFSL01000024_gene2068	3.267e-187	596.0	COG0500@1|root,COG1215@1|root,COG1215@2|Bacteria,COG2226@2|Bacteria,4NJWI@976|Bacteroidetes,2G252@200643|Bacteroidia,3XJUU@558415|Marinilabiliaceae	976|Bacteroidetes	MQ	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
TLS3_k127_4161894_1	929556.Solca_1315	7.383e-187	591.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1IQ5E@117747|Sphingobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
TLS3_k127_4161894_2	760192.Halhy_5956	4.638e-61	220.0	COG1427@1|root,COG1427@2|Bacteria,4NN4W@976|Bacteroidetes,1ISCN@117747|Sphingobacteriia	976|Bacteroidetes	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
TLS3_k127_4161894_0	153721.MYP_3421	5.279e-188	614.0	COG4222@1|root,COG4222@2|Bacteria,4NJ6G@976|Bacteroidetes,47QCY@768503|Cytophagia	976|Bacteroidetes	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	DUF839,Phytase-like
TLS3_k127_4196918_0	755732.Fluta_2459	7.41e-128	443.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IMQK@117743|Flavobacteriia,2PBES@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
TLS3_k127_4196918_1	1124780.ANNU01000021_gene2999	1.363e-109	365.0	COG2067@1|root,COG2067@2|Bacteria,4NE43@976|Bacteroidetes,47KIV@768503|Cytophagia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4196918_4	362418.IW19_04390	2.858e-14	83.0	COG2755@1|root,COG2755@2|Bacteria,4NRGK@976|Bacteroidetes,1IJSY@117743|Flavobacteriia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4196918_2	997884.HMPREF1068_02549	2.717e-91	317.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,2FM3F@200643|Bacteroidia,4AK8P@815|Bacteroidaceae	976|Bacteroidetes	M	Psort location CytoplasmicMembrane, score 10.00	algI	-	-	-	-	-	-	-	-	-	-	-	MBOAT
TLS3_k127_4196918_3	641524.ADICYQ_0204	2.418e-23	104.0	COG0216@1|root,COG0216@2|Bacteria,4PPXH@976|Bacteroidetes,47YSM@768503|Cytophagia	976|Bacteroidetes	J	RF-1 domain	yaeJ	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
TLS3_k127_4205847_6	1121859.KB890738_gene3232	2.341e-75	258.0	COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,47JWX@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
TLS3_k127_4205847_0	1346330.M472_17790	2.652e-195	624.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1IQ3R@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
TLS3_k127_4205847_3	1189612.A33Q_3093	1.085e-94	327.0	COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,47KYV@768503|Cytophagia	976|Bacteroidetes	V	efflux protein, MATE family	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
TLS3_k127_4205847_4	866536.Belba_1181	9.96e-91	306.0	COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,47K2K@768503|Cytophagia	976|Bacteroidetes	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
TLS3_k127_4205847_7	1120951.AUBG01000007_gene120	3.086e-74	259.0	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,1HXXE@117743|Flavobacteriia	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
TLS3_k127_4205847_5	1121957.ATVL01000010_gene551	8.247e-77	265.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,47KW6@768503|Cytophagia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
TLS3_k127_4205847_2	1122226.AUHX01000003_gene171	1.181e-118	391.0	COG0601@1|root,COG0601@2|Bacteria,4NGIJ@976|Bacteroidetes,1HYBQ@117743|Flavobacteriia	976|Bacteroidetes	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
TLS3_k127_4205847_1	755732.Fluta_2733	4.895e-123	417.0	COG1752@1|root,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,1HWZP@117743|Flavobacteriia,2PBJS@246874|Cryomorphaceae	976|Bacteroidetes	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	POTRA,Patatin
TLS3_k127_4227757_0	509635.N824_24725	1.599e-92	311.0	COG5526@1|root,COG5526@2|Bacteria,4P28W@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4227757_1	1173024.KI912151_gene2312	5.759e-52	200.0	2EFPZ@1|root,339G0@2|Bacteria,1GCBN@1117|Cyanobacteria,1JKTG@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4227757_2	1195236.CTER_4828	2.635e-25	109.0	COG3621@1|root,COG3621@2|Bacteria,1V83Q@1239|Firmicutes,24AVQ@186801|Clostridia	186801|Clostridia	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
TLS3_k127_4283445_0	1202532.FF52_02270	2.514e-298	927.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia,2NUEE@237|Flavobacterium	976|Bacteroidetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
TLS3_k127_4283445_18	1313301.AUGC01000001_gene1794	7.535e-42	171.0	2DMDZ@1|root,32QUA@2|Bacteria,4NSIY@976|Bacteroidetes	976|Bacteroidetes	S	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
TLS3_k127_4283445_23	869213.JCM21142_91	8.367e-23	113.0	2BVGH@1|root,32QVC@2|Bacteria,4NQ4G@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4283445_19	385682.AFSL01000062_gene1603	8.646e-33	134.0	2CC29@1|root,32RUM@2|Bacteria,4NS83@976|Bacteroidetes,2FS58@200643|Bacteroidia,3XIWH@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
TLS3_k127_4283445_1	755732.Fluta_4076	2.033e-292	908.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,1HWNY@117743|Flavobacteriia,2PAF4@246874|Cryomorphaceae	976|Bacteroidetes	L	Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
TLS3_k127_4283445_21	992406.RIA_1094	6.97e-27	113.0	COG0399@1|root,COG0399@2|Bacteria,4NVFZ@976|Bacteroidetes,1I3II@117743|Flavobacteriia	976|Bacteroidetes	M	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
TLS3_k127_4283445_6	531844.FIC_01275	5.619e-141	450.0	COG2013@1|root,COG2013@2|Bacteria,4NFNA@976|Bacteroidetes,1HWN1@117743|Flavobacteriia	976|Bacteroidetes	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
TLS3_k127_4283445_3	762903.Pedsa_2092	4.459e-175	554.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,1IPTY@117747|Sphingobacteriia	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
TLS3_k127_4283445_7	1296416.JACB01000031_gene2584	1.02e-134	435.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,1HWZM@117743|Flavobacteriia,2YJ4R@290174|Aquimarina	976|Bacteroidetes	G	Transketolase, thiamine diphosphate binding domain	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
TLS3_k127_4283445_8	926562.Oweho_1341	3.57e-112	379.0	COG2304@1|root,COG2304@2|Bacteria,4NJF1@976|Bacteroidetes,1I5HE@117743|Flavobacteriia,2PAI7@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
TLS3_k127_4283445_4	1538644.KO02_18735	8.985e-174	548.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,1IR3A@117747|Sphingobacteriia	976|Bacteroidetes	G	Transketolase	dxs	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
TLS3_k127_4283445_2	485917.Phep_4190	1.719e-182	582.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1IPRW@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
TLS3_k127_4283445_11	1121382.JQKG01000028_gene2797	7.781e-66	233.0	COG1496@1|root,COG1496@2|Bacteria,1WI9I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the multicopper oxidase YfiH RL5 family	-	GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
TLS3_k127_4283445_5	1416760.AYMS01000010_gene1045	1.739e-156	497.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1HX04@117743|Flavobacteriia,47HI8@76831|Myroides	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
TLS3_k127_4283445_13	929556.Solca_2213	1.057e-56	201.0	COG0328@1|root,COG0328@2|Bacteria,4NNQX@976|Bacteroidetes,1ISJ9@117747|Sphingobacteriia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
TLS3_k127_4283445_16	926562.Oweho_1029	4.958e-51	197.0	28H6U@1|root,2Z7J5@2|Bacteria,4NHUU@976|Bacteroidetes,1I8FZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4283445_14	1121373.KB903634_gene667	6.231e-56	202.0	COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,47J8W@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM TIGR02453 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
TLS3_k127_4283445_17	445970.ALIPUT_00210	2.084e-43	161.0	COG3169@1|root,COG3169@2|Bacteria,4NQH4@976|Bacteroidetes,2FT44@200643|Bacteroidia,22UIV@171550|Rikenellaceae	976|Bacteroidetes	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
TLS3_k127_4283445_12	1296415.JACC01000008_gene2359	2.141e-58	208.0	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,1HXJM@117743|Flavobacteriia,2YH62@290174|Aquimarina	976|Bacteroidetes	U	MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
TLS3_k127_4283445_9	984262.SGRA_1047	2.408e-110	367.0	COG0438@1|root,COG0438@2|Bacteria,4NJ6W@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
TLS3_k127_4283445_24	313606.M23134_08246	4.548e-16	83.0	2CUMY@1|root,32SVM@2|Bacteria,4NTF0@976|Bacteroidetes,47RDV@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_4283445_20	1279009.ADICEAN_02139	1.092e-32	147.0	COG1520@1|root,COG1520@2|Bacteria,4PKMD@976|Bacteroidetes,47QM2@768503|Cytophagia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4283445_10	509635.N824_05400	2.233e-101	337.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,1INNF@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
TLS3_k127_4283445_25	929713.NIASO_19360	8.06e-08	60.0	2E4AG@1|root,33IJ2@2|Bacteria,4P9RI@976|Bacteroidetes,1IUJQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4783
TLS3_k127_4283445_15	714943.Mucpa_4473	1.559e-52	189.0	COG1576@1|root,COG1576@2|Bacteria,4NMFP@976|Bacteroidetes,1ISE3@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
TLS3_k127_4283445_22	927658.AJUM01000037_gene2418	5.34e-23	112.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,2FNYT@200643|Bacteroidia,3XJ0F@558415|Marinilabiliaceae	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
TLS3_k127_4292901_2	1121012.AUKX01000031_gene1053	1.807e-37	147.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1I1CI@117743|Flavobacteriia,23GKK@178469|Arenibacter	976|Bacteroidetes	S	Acyl carrier protein phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
TLS3_k127_4292901_0	929556.Solca_0791	5.926e-188	597.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,1IPU5@117747|Sphingobacteriia	976|Bacteroidetes	M	Mur ligase middle domain	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_4292901_1	1313301.AUGC01000003_gene2099	6.491e-141	451.0	COG2877@1|root,COG2877@2|Bacteria,4NENN@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the KdsA family	-	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
TLS3_k127_4337708_2	1116369.KB890024_gene2089	1.779e-18	87.0	COG2153@1|root,COG2153@2|Bacteria,1MZHA@1224|Proteobacteria,2V859@28211|Alphaproteobacteria,43PKR@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
TLS3_k127_4337708_3	926556.Echvi_3891	9.831e-05	53.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_4337708_1	1189620.AJXL01000059_gene315	7.172e-76	260.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,1I83B@117743|Flavobacteriia,2NSB0@237|Flavobacterium	976|Bacteroidetes	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
TLS3_k127_4337708_0	688270.Celal_3808	1.209e-137	445.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,1HYC0@117743|Flavobacteriia,1F928@104264|Cellulophaga	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
TLS3_k127_4344198_0	929556.Solca_2077	3.28e-318	990.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1INPU@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
TLS3_k127_4344198_1	762903.Pedsa_0344	7.27e-106	352.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,1IRSG@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_4344198_2	700598.Niako_5142	7.427e-37	146.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,1IS2G@117747|Sphingobacteriia	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
TLS3_k127_4344198_4	880073.Calab_1994	9.498e-29	120.0	COG3762@1|root,COG3762@2|Bacteria,2NR8Y@2323|unclassified Bacteria	2|Bacteria	S	TPM domain	Z012_08985	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
TLS3_k127_4344198_3	1211813.CAPH01000006_gene1548	1.377e-31	129.0	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,2FN0H@200643|Bacteroidia,22UF2@171550|Rikenellaceae	976|Bacteroidetes	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
TLS3_k127_436671_11	865937.Gilli_2303	5.531e-58	203.0	COG3746@1|root,COG3746@2|Bacteria,4NG5Z@976|Bacteroidetes,1I77C@117743|Flavobacteriia	976|Bacteroidetes	P	Pfam Phosphate-selective porin O and P	oprP	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
TLS3_k127_436671_4	1185876.BN8_05489	3.634e-162	522.0	COG0306@1|root,COG0306@2|Bacteria,4NE7J@976|Bacteroidetes,47KEG@768503|Cytophagia	976|Bacteroidetes	P	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
TLS3_k127_436671_2	926549.KI421517_gene1405	1.483e-209	665.0	COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes,47JSX@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
TLS3_k127_436671_14	509635.N824_16125	5.46e-39	150.0	COG3620@1|root,COG3620@2|Bacteria,4PNCJ@976|Bacteroidetes	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_436671_9	1121012.AUKX01000059_gene1380	1.067e-63	224.0	COG2184@1|root,COG2184@2|Bacteria,4NM5F@976|Bacteroidetes,1HYYF@117743|Flavobacteriia	976|Bacteroidetes	D	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
TLS3_k127_436671_7	761193.Runsl_4415	2.077e-76	259.0	28IMK@1|root,2Z8N2@2|Bacteria,4P0NE@976|Bacteroidetes	976|Bacteroidetes	L	Dam-replacing family	-	-	3.1.21.4	ko:K01155	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DpnI
TLS3_k127_436671_15	706436.HMPREF9074_07826	3.773e-35	136.0	28IMK@1|root,2Z8N2@2|Bacteria,4P0NE@976|Bacteroidetes	976|Bacteroidetes	L	Dam-replacing family	-	-	3.1.21.4	ko:K01155	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DpnI
TLS3_k127_436671_18	929556.Solca_0707	8.033e-08	55.0	2BA9N@1|root,323PV@2|Bacteria,4NNB5@976|Bacteroidetes,1IUP2@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_436671_19	1120968.AUBX01000015_gene3895	0.0001484	47.0	2BA9N@1|root,323PV@2|Bacteria,4NNB5@976|Bacteroidetes,47PM5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_436671_13	1033737.CAEV01000056_gene3724	1.817e-42	158.0	COG2824@1|root,COG2824@2|Bacteria,1V6NA@1239|Firmicutes,24J9K@186801|Clostridia,36K63@31979|Clostridiaceae	186801|Clostridia	P	Alkylphosphonate utilization operon protein PhnA	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
TLS3_k127_436671_6	1454007.JAUG01000079_gene4550	3.248e-77	264.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1IQ4U@117747|Sphingobacteriia	976|Bacteroidetes	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
TLS3_k127_436671_3	1408473.JHXO01000011_gene3152	1.576e-162	550.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,2FM3C@200643|Bacteroidia	976|Bacteroidetes	G	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
TLS3_k127_436671_12	755732.Fluta_1586	9.063e-56	216.0	COG4773@1|root,COG4773@2|Bacteria,4PKTX@976|Bacteroidetes,1HXIR@117743|Flavobacteriia,2PB19@246874|Cryomorphaceae	976|Bacteroidetes	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
TLS3_k127_436671_5	755732.Fluta_1927	8.585e-110	362.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
TLS3_k127_436671_10	313595.P700755_001752	2.434e-58	212.0	COG2304@1|root,COG2304@2|Bacteria,4NKZ6@976|Bacteroidetes,1IFZZ@117743|Flavobacteriia,4C41B@83612|Psychroflexus	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_436671_16	985255.APHJ01000018_gene3031	8.945e-33	136.0	COG4704@1|root,COG4704@2|Bacteria,4NUMP@976|Bacteroidetes,1I5WC@117743|Flavobacteriia	976|Bacteroidetes	S	Fibrobacter succinogenes major domain (Fib_succ_major)	-	-	-	-	-	-	-	-	-	-	-	-	BACON,Fib_succ_major
TLS3_k127_436671_0	468059.AUHA01000002_gene769	0.0	1099.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1IPFU@117747|Sphingobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
TLS3_k127_436671_1	1185876.BN8_00147	1.687e-258	818.0	COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
TLS3_k127_436671_8	388413.ALPR1_20173	5.832e-72	265.0	COG4796@1|root,COG4796@2|Bacteria,4PM2P@976|Bacteroidetes,47Y0K@768503|Cytophagia	976|Bacteroidetes	U	Type ii and iii secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,DUF4974,STN
TLS3_k127_4431249_0	313606.M23134_05475	6.227e-230	750.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47MEM@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
TLS3_k127_443428_0	1408433.JHXV01000018_gene3848	4.571e-68	257.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1I7ZV@117743|Flavobacteriia,2PAMN@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
TLS3_k127_446327_2	468059.AUHA01000003_gene1902	1.124e-78	270.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
TLS3_k127_446327_1	153721.MYP_226	9.499e-126	425.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia	976|Bacteroidetes	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS3_k127_446327_3	869213.JCM21142_124656	3.505e-09	64.0	2DM48@1|root,31NG2@2|Bacteria,4NQJF@976|Bacteroidetes,47QMX@768503|Cytophagia	976|Bacteroidetes	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
TLS3_k127_446327_0	485917.Phep_1412	3.868e-186	593.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1IP3X@117747|Sphingobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TLS3_k127_446327_5	980584.AFPB01000151_gene489	0.0001758	50.0	COG3291@1|root,COG4412@1|root,COG5297@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.4	ko:K01179,ko:K20276,ko:K21449	ko00500,ko01100,ko02024,map00500,map01100,map02024	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko02000	1.B.40.2	GH5,GH9	-	CARDB,CBM_2,CBM_3,Glyco_hydro_9,PKD,Peptidase_M30
TLS3_k127_446327_4	1122176.KB903600_gene5285	1.82e-06	56.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
TLS3_k127_446443_6	1048983.EL17_04395	1.12e-19	89.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,47QSI@768503|Cytophagia	976|Bacteroidetes	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
TLS3_k127_446443_5	391596.PBAL39_10731	5.575e-25	112.0	COG0454@1|root,COG0456@2|Bacteria,4NQVT@976|Bacteroidetes,1IXKP@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	paiA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
TLS3_k127_446443_0	143224.JQMD01000002_gene4197	1.654e-294	917.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,1HXV3@117743|Flavobacteriia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
TLS3_k127_446443_4	649349.Lbys_1708	2.408e-47	180.0	COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes,47NW3@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
TLS3_k127_446443_3	153721.MYP_608	7.746e-59	208.0	COG1666@1|root,COG1666@2|Bacteria,4NMBZ@976|Bacteroidetes,47Q82@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF520)	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
TLS3_k127_446443_2	1123373.ATXI01000008_gene1560	5.249e-135	437.0	COG2605@1|root,COG2605@2|Bacteria,2GIF3@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
TLS3_k127_446443_1	929703.KE386491_gene841	8.638e-139	448.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,47JZR@768503|Cytophagia	976|Bacteroidetes	F	PFAM SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
TLS3_k127_446443_7	1121912.AUHD01000013_gene924	1.138e-05	54.0	COG3291@1|root,COG3866@1|root,COG5492@1|root,COG3291@2|Bacteria,COG3866@2|Bacteria,COG5492@2|Bacteria,4P09P@976|Bacteroidetes,1I0G9@117743|Flavobacteriia	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_3,Laminin_G_3,Lipase_GDSL_2,fn3
TLS3_k127_446811_0	485918.Cpin_6937	6.728e-109	368.0	COG0815@1|root,COG0815@2|Bacteria,4NG4X@976|Bacteroidetes,1IQGK@117747|Sphingobacteriia	976|Bacteroidetes	M	apolipoprotein N-acyltransferase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
TLS3_k127_446811_1	1250232.JQNJ01000001_gene3521	7.709e-16	77.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1HWJZ@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_4469512_1	468059.AUHA01000005_gene2435	1.628e-227	717.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,1IVAT@117747|Sphingobacteriia	976|Bacteroidetes	F	COGs COG0737 5'-nucleotidase 2' 3'-cyclic phosphodiesterase and related esterase	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
TLS3_k127_4469512_2	468059.AUHA01000005_gene2437	2.56e-81	276.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1ISBB@117747|Sphingobacteriia	976|Bacteroidetes	K	Crp-like helix-turn-helix domain	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TLS3_k127_4469512_3	1121889.AUDM01000002_gene262	2.452e-12	69.0	COG3224@1|root,COG3224@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09932	-	-	-	-	ko00000	-	-	-	ABM
TLS3_k127_4469512_0	1123248.KB893359_gene2101	8.457e-252	795.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,1IP4V@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidase M13	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
TLS3_k127_4469512_4	880070.Cycma_4268	1.621e-09	64.0	COG0589@1|root,COG0589@2|Bacteria,4NGD6@976|Bacteroidetes,47XGH@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_4472629_2	1313421.JHBV01000041_gene3455	1.021e-32	127.0	COG1741@1|root,COG1741@2|Bacteria,4NFZD@976|Bacteroidetes,1IPEQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
TLS3_k127_4472629_0	760192.Halhy_4968	1.002e-214	682.0	COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,4NGKK@976|Bacteroidetes,1IRV5@117747|Sphingobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2
TLS3_k127_4472629_1	1408433.JHXV01000019_gene1916	2.217e-39	158.0	COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,1IKD0@117743|Flavobacteriia,2PAFR@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_4497398_3	1217714.F975_00695	1.509e-27	115.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,3NK9X@468|Moraxellaceae	1236|Gammaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	dcyD	-	3.5.99.7,4.4.1.15	ko:K01505,ko:K05396	ko00270,map00270	-	R00997,R01874	RC00382,RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
TLS3_k127_4497398_0	1408433.JHXV01000001_gene689	1.261e-109	377.0	COG0457@1|root,COG0457@2|Bacteria,4NE2V@976|Bacteroidetes,1HWRP@117743|Flavobacteriia,2PAI5@246874|Cryomorphaceae	976|Bacteroidetes	S	FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6,TPR_8
TLS3_k127_4497398_2	1408433.JHXV01000015_gene1725	2.352e-37	144.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,1ICR4@117743|Flavobacteriia,2PBUN@246874|Cryomorphaceae	976|Bacteroidetes	T	Histidine kinase-like ATPase domain	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
TLS3_k127_4497398_1	153721.MYP_1663	2.767e-63	231.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,47NNE@768503|Cytophagia	976|Bacteroidetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
TLS3_k127_450655_12	1227739.Hsw_0565	7.481e-08	66.0	COG3291@1|root,COG4625@1|root,COG3291@2|Bacteria,COG4625@2|Bacteria,4NDZC@976|Bacteroidetes,47YR2@768503|Cytophagia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
TLS3_k127_450655_1	984262.SGRA_2537	5.242e-214	702.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes	976|Bacteroidetes	DZ	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
TLS3_k127_450655_10	1347342.BN863_35230	7.743e-13	72.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1I54R@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
TLS3_k127_450655_2	1408433.JHXV01000007_gene2833	2.21e-191	608.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1HXBS@117743|Flavobacteriia,2PA8A@246874|Cryomorphaceae	976|Bacteroidetes	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
TLS3_k127_450655_5	468059.AUHA01000006_gene2853	4.382e-152	485.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1IP11@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
TLS3_k127_450655_7	927658.AJUM01000011_gene1306	2.457e-86	305.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,2G1ZJ@200643|Bacteroidia,3XIJR@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_450655_9	1122225.AULQ01000005_gene2626	1.023e-24	114.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,1I1E3@117743|Flavobacteriia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
TLS3_k127_450655_6	1168034.FH5T_08385	3.846e-115	399.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,2FQ6Y@200643|Bacteroidia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
TLS3_k127_450655_11	1408433.JHXV01000030_gene1416	7.047e-11	75.0	COG1520@1|root,COG1520@2|Bacteria,4NEVC@976|Bacteroidetes,1IJFE@117743|Flavobacteriia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_450655_0	700598.Niako_6196	2.625e-276	867.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,1IPZY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S46	dpp7	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
TLS3_k127_450655_3	700598.Niako_5074	5.208e-175	558.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,1IQZJ@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
TLS3_k127_450655_8	714943.Mucpa_2509	1.786e-46	172.0	COG1595@1|root,COG1595@2|Bacteria,4NMM3@976|Bacteroidetes,1IPYA@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	sigR_3	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_450655_4	929703.KE386491_gene557	2.593e-156	500.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,47M2W@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
TLS3_k127_450906_0	1408433.JHXV01000006_gene2788	2.999e-140	473.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1HYBR@117743|Flavobacteriia,2PAP0@246874|Cryomorphaceae	976|Bacteroidetes	E	peptidase M1	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
TLS3_k127_450906_2	755732.Fluta_2843	2.481e-93	312.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1HWZZ@117743|Flavobacteriia,2PADT@246874|Cryomorphaceae	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
TLS3_k127_450906_1	643867.Ftrac_0939	1.592e-118	387.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,47M72@768503|Cytophagia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_4515046_2	755732.Fluta_1284	2.069e-27	128.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
TLS3_k127_4515046_1	313606.M23134_01441	5.311e-151	488.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,47JJH@768503|Cytophagia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1,2.6.1.88	ko:K00812,ko:K10907,ko:K14287	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052,R08618	RC00006,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_4515046_0	865938.Weevi_0083	5.348e-156	499.0	COG1503@1|root,COG1503@2|Bacteria,4NHF3@976|Bacteroidetes,1I0UG@117743|Flavobacteriia	976|Bacteroidetes	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_451821_6	1121896.JMLU01000007_gene161	3.241e-30	122.0	COG3620@1|root,COG3620@2|Bacteria,4NQCR@976|Bacteroidetes,1IJYR@117743|Flavobacteriia,2NWW7@237|Flavobacterium	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
TLS3_k127_451821_4	1123057.P872_22160	1.889e-37	144.0	COG4679@1|root,COG4679@2|Bacteria,4NPPR@976|Bacteroidetes,47Q24@768503|Cytophagia	976|Bacteroidetes	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
TLS3_k127_451821_1	929556.Solca_4414	1.976e-174	556.0	COG2195@1|root,COG2195@2|Bacteria,4NE7N@976|Bacteroidetes,1INZR@117747|Sphingobacteriia	976|Bacteroidetes	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_451821_0	929556.Solca_1149	3.857e-181	574.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,1IP06@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
TLS3_k127_451821_5	1392498.JQLH01000001_gene301	1.495e-35	138.0	COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,1I2WQ@117743|Flavobacteriia,2PHM1@252356|Maribacter	976|Bacteroidetes	S	Pfam:DUF59	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
TLS3_k127_451821_3	1120951.AUBG01000010_gene1953	1.475e-50	182.0	COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,1I187@117743|Flavobacteriia	976|Bacteroidetes	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
TLS3_k127_451821_2	1287488.HMPREF0671_01510	2.008e-130	427.0	COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,2FPF8@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
TLS3_k127_4518861_0	485917.Phep_2329	6.195e-217	677.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1INZ7@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_4518861_6	643867.Ftrac_2983	2.038e-15	93.0	COG1361@1|root,COG2931@1|root,COG3391@1|root,COG3420@1|root,COG3468@1|root,COG5492@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,COG3420@2|Bacteria,COG3468@2|Bacteria,COG5492@2|Bacteria,4PMF3@976|Bacteroidetes,47Y61@768503|Cytophagia	976|Bacteroidetes	MN	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS
TLS3_k127_4518861_1	1408433.JHXV01000011_gene2054	2.209e-119	435.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IJY5@117743|Flavobacteriia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gly_rich,HYR,Laminin_G_3,PKD,SprB
TLS3_k127_4518861_3	925409.KI911562_gene2185	3.381e-25	125.0	COG3055@1|root,COG3391@1|root,COG4935@1|root,COG3055@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,4PMIF@976|Bacteroidetes	976|Bacteroidetes	E	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	HYR,Laminin_G_3
TLS3_k127_4518861_4	313606.M23134_08279	3.044e-24	122.0	COG1361@1|root,COG1409@1|root,COG2931@1|root,COG3420@1|root,COG4886@1|root,COG1361@2|Bacteria,COG1409@2|Bacteria,COG2931@2|Bacteria,COG3420@2|Bacteria,COG4886@2|Bacteria,4PMET@976|Bacteroidetes	976|Bacteroidetes	Q	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_4518861_5	1121012.AUKX01000046_gene2674	2.284e-18	88.0	2C0U8@1|root,34BBX@2|Bacteria,4P60W@976|Bacteroidetes,1IA4F@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4518861_2	760192.Halhy_1388	3.15e-44	161.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,1IQF9@117747|Sphingobacteriia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
TLS3_k127_452422_2	755732.Fluta_1926	6.853e-106	348.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia,2PBC6@246874|Cryomorphaceae	976|Bacteroidetes	C	Aldehyde dehydrogenase family	aldB	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_452422_3	1121104.AQXH01000001_gene1193	5.01e-103	344.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
TLS3_k127_452422_8	1121007.AUML01000037_gene2015	9.101e-47	184.0	COG3146@1|root,COG3146@2|Bacteria,4NI7H@976|Bacteroidetes,1I0KW@117743|Flavobacteriia,2YJ8Q@290174|Aquimarina	976|Bacteroidetes	S	8-amino-7-oxononanoate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB_like
TLS3_k127_452422_0	391587.KAOT1_17228	1.638e-257	801.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1HX3I@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_452422_11	745718.JADT01000020_gene248	1.67e-09	71.0	COG3291@1|root,COG5492@1|root,COG3291@2|Bacteria,COG5492@2|Bacteria,4NG09@976|Bacteroidetes,1IKC9@117743|Flavobacteriia	976|Bacteroidetes	N	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
TLS3_k127_452422_5	1123277.KB893195_gene5580	5.892e-74	276.0	COG2374@1|root,COG3291@1|root,COG5492@1|root,COG2374@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	CHU_C,Exo_endo_phos,LTD,PKD
TLS3_k127_452422_1	269798.CHU_3813	2.995e-117	383.0	COG2908@1|root,COG2908@2|Bacteria,4NFD8@976|Bacteroidetes,47MNV@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
TLS3_k127_452422_4	411477.PARMER_01379	9.734e-97	328.0	COG0707@1|root,COG0707@2|Bacteria,4PKSS@976|Bacteroidetes,2FMCT@200643|Bacteroidia,22WGK@171551|Porphyromonadaceae	976|Bacteroidetes	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_3
TLS3_k127_452422_6	873533.HMPREF0663_12378	4.111e-64	231.0	COG1597@1|root,COG1597@2|Bacteria,4NJWB@976|Bacteroidetes,2FMGJ@200643|Bacteroidia	976|Bacteroidetes	I	lipid kinase, YegS Rv2252 BmrU family	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
TLS3_k127_452422_7	880071.Fleli_2756	2.255e-58	212.0	COG0394@1|root,COG0394@2|Bacteria,4NE8C@976|Bacteroidetes,47PXK@768503|Cytophagia	976|Bacteroidetes	T	PFAM Low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1,3.1.3.48	ko:K01104,ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
TLS3_k127_452422_10	1121373.KB903628_gene1436	9.062e-24	110.0	2BVJ7@1|root,32QX6@2|Bacteria,4NR17@976|Bacteroidetes,47QGI@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
TLS3_k127_452422_9	153721.MYP_3423	1.539e-26	113.0	COG2010@1|root,COG2010@2|Bacteria,4P69S@976|Bacteroidetes,47W66@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4535826_5	1408433.JHXV01000012_gene4005	1.094e-24	107.0	COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,1I2WH@117743|Flavobacteriia,2PB4C@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
TLS3_k127_4535826_0	1305737.JAFX01000001_gene1986	2.55e-152	487.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,47K34@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
TLS3_k127_4535826_2	1121904.ARBP01000006_gene3769	5.195e-71	252.0	COG0741@1|root,COG0741@2|Bacteria,4P2CQ@976|Bacteroidetes	976|Bacteroidetes	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
TLS3_k127_4535826_4	1380384.JADN01000004_gene1752	2.405e-33	142.0	COG2143@1|root,COG2143@2|Bacteria,4NM6B@976|Bacteroidetes,1I16Q@117743|Flavobacteriia	976|Bacteroidetes	O	COG2143 Thioredoxin-related protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7
TLS3_k127_4535826_6	755732.Fluta_2307	6.341e-24	110.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia,2PABJ@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Response regulator receiver domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_4535826_1	755732.Fluta_2857	1.062e-148	493.0	COG5492@1|root,COG5492@2|Bacteria,4NH7Q@976|Bacteroidetes,1HXMH@117743|Flavobacteriia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	TIG
TLS3_k127_4535826_3	755732.Fluta_2858	5.015e-65	231.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,1HXUT@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug,TonB_dep_Rec
TLS3_k127_454594_5	1453500.AT05_10425	7.658e-66	226.0	COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,1I18N@117743|Flavobacteriia	976|Bacteroidetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
TLS3_k127_454594_4	1121373.KB903663_gene1156	5.089e-68	233.0	COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,47P7P@768503|Cytophagia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
TLS3_k127_454594_0	525373.HMPREF0766_12807	0.0	1160.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1INUJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
TLS3_k127_454594_6	1500281.JQKZ01000004_gene3580	1.549e-51	186.0	COG0051@1|root,COG0051@2|Bacteria,4NQ65@976|Bacteroidetes,1I2VK@117743|Flavobacteriia,3ZS3Z@59732|Chryseobacterium	976|Bacteroidetes	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
TLS3_k127_454594_2	743722.Sph21_1714	5.532e-95	314.0	COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,1IPGZ@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
TLS3_k127_454594_3	926556.Echvi_0254	9.267e-84	282.0	COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,47J8V@768503|Cytophagia	976|Bacteroidetes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
TLS3_k127_454594_8	908612.HMPREF9720_2538	7.501e-32	126.0	COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,2FT3A@200643|Bacteroidia,22VE2@171550|Rikenellaceae	976|Bacteroidetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
TLS3_k127_454594_1	1211813.CAPH01000013_gene457	1.687e-123	400.0	COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes,2FN89@200643|Bacteroidia,22UBN@171550|Rikenellaceae	976|Bacteroidetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
TLS3_k127_454594_7	869213.JCM21142_31250	2.091e-41	153.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,47QCA@768503|Cytophagia	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
TLS3_k127_4556697_4	742767.HMPREF9456_03108	7.451e-85	286.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,2FSBV@200643|Bacteroidia,22ZCP@171551|Porphyromonadaceae	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	yadF	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
TLS3_k127_4556697_5	1121899.Q764_05105	2.456e-53	192.0	COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes,1I2YF@117743|Flavobacteriia,2NWF0@237|Flavobacterium	976|Bacteroidetes	O	Peroxiredoxin	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
TLS3_k127_4556697_8	491205.JARQ01000002_gene155	5.84e-29	119.0	COG2085@1|root,COG2085@2|Bacteria,4NEC7@976|Bacteroidetes,1INB1@117743|Flavobacteriia,3ZSZ8@59732|Chryseobacterium	976|Bacteroidetes	S	Acetohydroxy acid isomeroreductase, NADPH-binding domain	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
TLS3_k127_4556697_9	1233951.IO90_13885	1.228e-25	114.0	COG3781@1|root,COG3781@2|Bacteria,4NGJ0@976|Bacteroidetes,1HYG9@117743|Flavobacteriia,3HIW7@358033|Chryseobacterium	976|Bacteroidetes	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
TLS3_k127_4556697_7	1123278.KB893577_gene1326	1.004e-40	158.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,4NVG3@976|Bacteroidetes,47QRI@768503|Cytophagia	976|Bacteroidetes	S	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
TLS3_k127_4556697_3	761193.Runsl_2216	3.714e-91	307.0	COG2520@1|root,COG2520@2|Bacteria,4NNG5@976|Bacteroidetes,47PX7@768503|Cytophagia	976|Bacteroidetes	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
TLS3_k127_4556697_6	1121899.Q764_05105	6.031e-53	189.0	COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes,1I2YF@117743|Flavobacteriia,2NWF0@237|Flavobacterium	976|Bacteroidetes	O	Peroxiredoxin	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
TLS3_k127_4556697_2	880073.Calab_0763	7.329e-95	326.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,Cu_amine_oxidN1,DLH,DUF3887,Hydrolase_4,Peptidase_S9
TLS3_k127_4556697_0	1313421.JHBV01000024_gene5040	1.713e-181	576.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes	976|Bacteroidetes	Q	Fumarylacetoacetase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
TLS3_k127_4556697_1	761193.Runsl_3718	1.224e-114	377.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,47K1Q@768503|Cytophagia	976|Bacteroidetes	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_4558180_9	1121898.Q766_11605	3.126e-23	99.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,1HX75@117743|Flavobacteriia,2NTDV@237|Flavobacterium	976|Bacteroidetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
TLS3_k127_4558180_3	655815.ZPR_0662	1.653e-226	712.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,1HXDR@117743|Flavobacteriia	976|Bacteroidetes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
TLS3_k127_4558180_0	649349.Lbys_0863	0.0	1536.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,4NFRF@976|Bacteroidetes,47K8Q@768503|Cytophagia	976|Bacteroidetes	E	Vitamin B12 dependent methionine synthase activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
TLS3_k127_4558180_8	1454007.JAUG01000001_gene3724	2.99e-36	142.0	COG4319@1|root,COG4319@2|Bacteria,4NS9D@976|Bacteroidetes,1ITI3@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
TLS3_k127_4558180_6	153721.MYP_1007	4.327e-81	278.0	COG1682@1|root,COG1682@2|Bacteria,4NF36@976|Bacteroidetes,47NFE@768503|Cytophagia	976|Bacteroidetes	GM	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
TLS3_k127_4558180_1	153721.MYP_2367	0.0	1050.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,47M8U@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
TLS3_k127_4558180_4	1121904.ARBP01000006_gene4002	2.655e-130	428.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,47KGU@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
TLS3_k127_4558180_7	929556.Solca_1977	1.89e-38	149.0	COG4430@1|root,COG4430@2|Bacteria,4NR0U@976|Bacteroidetes,1IT28@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
TLS3_k127_4558180_5	1120965.AUBV01000008_gene1943	7.569e-121	398.0	COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,47KTC@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
TLS3_k127_4558180_2	153721.MYP_1313	4.483e-240	747.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,47KGI@768503|Cytophagia	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
TLS3_k127_4558180_10	1408813.AYMG01000011_gene832	7.49e-19	93.0	COG2091@1|root,COG2091@2|Bacteria,4NSBI@976|Bacteroidetes,1ITW4@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	-	-	-	-	-	-	-	-	-	ACPS
TLS3_k127_4574335_0	485917.Phep_4119	1.863e-154	490.0	COG0492@1|root,COG0492@2|Bacteria,4NEQM@976|Bacteroidetes,1IWCM@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_4574335_2	1120951.AUBG01000011_gene2256	5.05e-58	214.0	COG4671@1|root,COG4671@2|Bacteria,4PM9I@976|Bacteroidetes,1IJNR@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
TLS3_k127_4574335_1	762903.Pedsa_0169	2.399e-136	436.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,1IP1Y@117747|Sphingobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
TLS3_k127_46233_2	984262.SGRA_2949	6.824e-14	75.0	COG1629@1|root,COG1629@2|Bacteria,4NFW1@976|Bacteroidetes,1IQ77@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
TLS3_k127_46233_1	376686.Fjoh_1169	9.392e-24	115.0	COG3291@1|root,COG4085@1|root,COG3291@2|Bacteria,COG4085@2|Bacteria,4NIB0@976|Bacteroidetes,1HWVQ@117743|Flavobacteriia,2NUXU@237|Flavobacterium	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5017,LTD
TLS3_k127_46233_0	755732.Fluta_4067	2.856e-209	659.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1HWVH@117743|Flavobacteriia,2PBCM@246874|Cryomorphaceae	976|Bacteroidetes	G	PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TLS3_k127_4661699_1	313598.MED152_03890	1.612e-229	724.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1HY2B@117743|Flavobacteriia,3VW4D@52959|Polaribacter	976|Bacteroidetes	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
TLS3_k127_4661699_0	926562.Oweho_1567	4.124e-264	830.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1HXSC@117743|Flavobacteriia,2PA4Q@246874|Cryomorphaceae	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
TLS3_k127_4661699_4	1348583.ATLH01000028_gene96	1.17e-34	139.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,1I1ZH@117743|Flavobacteriia,1F9BH@104264|Cellulophaga	976|Bacteroidetes	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
TLS3_k127_4661699_3	1408473.JHXO01000006_gene1203	3.27e-50	188.0	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,2FMM7@200643|Bacteroidia	976|Bacteroidetes	H	biotin acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
TLS3_k127_4661699_2	1492737.FEM08_01740	2.565e-74	260.0	COG1090@1|root,COG1090@2|Bacteria,4NINM@976|Bacteroidetes,1HXRB@117743|Flavobacteriia,2NSBA@237|Flavobacterium	976|Bacteroidetes	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
TLS3_k127_4661699_5	1150600.ADIARSV_3597	6.988e-23	100.0	COG3411@1|root,COG3411@2|Bacteria,4NT2H@976|Bacteroidetes,1IT6E@117747|Sphingobacteriia	976|Bacteroidetes	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4734279_3	1121373.KB903632_gene398	1.111e-84	286.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,47PCQ@768503|Cytophagia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
TLS3_k127_4734279_1	760192.Halhy_0423	1.914e-226	709.0	COG0659@1|root,COG0659@2|Bacteria,4NF1C@976|Bacteroidetes,1ISE6@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfate permease family	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
TLS3_k127_4734279_2	313606.M23134_05445	7.389e-116	377.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes,47U0W@768503|Cytophagia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
TLS3_k127_4734279_0	1492737.FEM08_34980	1.556e-264	827.0	COG1132@1|root,COG1132@2|Bacteria,4NEBS@976|Bacteroidetes,1I0M1@117743|Flavobacteriia,2NU7G@237|Flavobacterium	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS3_k127_4734279_4	1408433.JHXV01000001_gene833	5.729e-20	102.0	2A92F@1|root,30Y6G@2|Bacteria,4PBXE@976|Bacteroidetes,1IMRH@117743|Flavobacteriia,2PBQ0@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4775465_2	153721.MYP_2625	4.928e-126	421.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NEK7@976|Bacteroidetes,47MJ9@768503|Cytophagia	976|Bacteroidetes	L	PFAM Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
TLS3_k127_4775465_3	700598.Niako_0938	2.425e-116	381.0	COG3000@1|root,COG3000@2|Bacteria,4NI60@976|Bacteroidetes,1IQSK@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
TLS3_k127_4775465_5	1121904.ARBP01000013_gene448	7.763e-62	220.0	COG1778@1|root,COG1778@2|Bacteria,4NMFZ@976|Bacteroidetes,47PAE@768503|Cytophagia	976|Bacteroidetes	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	-
TLS3_k127_4775465_0	761193.Runsl_0202	5.004e-152	486.0	COG0176@1|root,COG2905@1|root,COG0176@2|Bacteria,COG2905@2|Bacteria,4NIUX@976|Bacteroidetes,47KKQ@768503|Cytophagia	976|Bacteroidetes	GT	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,TAL_FSA
TLS3_k127_4775465_8	1237149.C900_04025	1.714e-11	74.0	2AEI8@1|root,331SH@2|Bacteria,4NWWM@976|Bacteroidetes,47S6K@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4775465_6	1121481.AUAS01000015_gene2212	9.885e-37	159.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47JD6@768503|Cytophagia	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43,fn3
TLS3_k127_4775465_4	926562.Oweho_1916	2.546e-79	289.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,Laminin_G_3,MAM,PKD
TLS3_k127_4775465_7	1279009.ADICEAN_02294	9.184e-30	137.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,4NGRJ@976|Bacteroidetes,47NXA@768503|Cytophagia	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Cleaved_Adhesin,PKD,Peptidase_M43,fn3
TLS3_k127_4775465_1	1349785.BAUG01000043_gene2222	3.288e-147	484.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1HWS4@117743|Flavobacteriia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
TLS3_k127_4787193_4	485917.Phep_2918	4.212e-71	242.0	COG1788@1|root,COG1788@2|Bacteria,4NF3T@976|Bacteroidetes,1IQP0@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoA	-	2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01031,ko:K01034	ko00072,ko00280,ko00310,ko00362,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00362,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R02990,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
TLS3_k127_4787193_0	1121129.KB903360_gene3385	4.514e-244	775.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,2FNAU@200643|Bacteroidia,22W8Z@171551|Porphyromonadaceae	976|Bacteroidetes	M	Penicillin-binding Protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
TLS3_k127_4787193_6	1233950.IW22_23005	9.441e-42	162.0	COG1073@1|root,COG1073@2|Bacteria,4NP3H@976|Bacteroidetes,1I92T@117743|Flavobacteriia,3ZPGU@59732|Chryseobacterium	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
TLS3_k127_4787193_3	1121129.KB903359_gene1547	3.808e-119	397.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,2FNA1@200643|Bacteroidia,22W55@171551|Porphyromonadaceae	976|Bacteroidetes	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
TLS3_k127_4787193_1	762903.Pedsa_0041	2.742e-188	606.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1IQ2C@117747|Sphingobacteriia	976|Bacteroidetes	M	Penicillin-binding protein 2	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
TLS3_k127_4787193_7	385682.AFSL01000023_gene2167	3.195e-30	126.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,2FPJA@200643|Bacteroidia,3XK2I@558415|Marinilabiliaceae	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4787193_5	1408473.JHXO01000011_gene2963	1.509e-59	216.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,2FMWS@200643|Bacteroidia	976|Bacteroidetes	M	shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
TLS3_k127_4787193_2	755732.Fluta_1895	2.154e-145	463.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,1HXDD@117743|Flavobacteriia,2PACA@246874|Cryomorphaceae	976|Bacteroidetes	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
TLS3_k127_4792616_0	1125971.ASJB01000030_gene1049	2.49e-50	199.0	COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria	201174|Actinobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
TLS3_k127_4808860_6	485918.Cpin_3091	1.368e-14	78.0	COG2850@1|root,COG2850@2|Bacteria,4NEJI@976|Bacteroidetes,1IRY2@117747|Sphingobacteriia	976|Bacteroidetes	S	Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
TLS3_k127_4808860_2	1341155.FSS13T_24850	2.943e-52	198.0	28IZ7@1|root,2Z8WQ@2|Bacteria,4NIAK@976|Bacteroidetes,1I09F@117743|Flavobacteriia,2NTW2@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4808860_3	873517.HMPREF1977_1495	2.041e-51	185.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1I1XN@117743|Flavobacteriia,1ERU9@1016|Capnocytophaga	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
TLS3_k127_4808860_1	714943.Mucpa_1460	1.006e-65	228.0	COG2065@1|root,COG2065@2|Bacteria,4NFI1@976|Bacteroidetes,1IQWE@117747|Sphingobacteriia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
TLS3_k127_4808860_4	1469557.JSWF01000022_gene511	1.187e-39	153.0	COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,1I30V@117743|Flavobacteriia	976|Bacteroidetes	S	Damage-inducible protein DinB	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_4808860_0	1150600.ADIARSV_0223	6.694e-160	508.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,1IP8Y@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
TLS3_k127_4808860_5	1392498.JQLH01000001_gene3621	1.106e-34	134.0	COG1541@1|root,COG1541@2|Bacteria,4PKAN@976|Bacteroidetes,1HX4F@117743|Flavobacteriia,2PGKT@252356|Maribacter	976|Bacteroidetes	H	Acyl-protein synthetase, LuxE	luxE	-	-	-	-	-	-	-	-	-	-	-	LuxE
TLS3_k127_4819886_2	755732.Fluta_0832	1.178e-19	91.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1HX6Z@117743|Flavobacteriia,2PADA@246874|Cryomorphaceae	976|Bacteroidetes	I	PFAM Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_4819886_0	929556.Solca_0293	2.476e-118	405.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1IRAV@117747|Sphingobacteriia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4819886_1	555500.I215_03710	2.363e-114	373.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,1HXDZ@117743|Flavobacteriia	976|Bacteroidetes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_4839280_10	1270196.JCKI01000008_gene1446	6.077e-26	117.0	COG0457@1|root,COG0457@2|Bacteria,4NEV2@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
TLS3_k127_4839280_15	714943.Mucpa_2551	4.19e-06	49.0	2EIUI@1|root,33CJV@2|Bacteria,4NYR6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4839280_3	468059.AUHA01000002_gene680	6.721e-200	634.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1IQ78@117747|Sphingobacteriia	976|Bacteroidetes	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
TLS3_k127_4839280_2	1168034.FH5T_21745	7.248e-206	659.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,2FQ14@200643|Bacteroidia	976|Bacteroidetes	S	Glycosyltransferase, group 2 family protein	wbbL	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_4839280_11	641526.ADIWIN_1088	3.584e-23	104.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1HX34@117743|Flavobacteriia	976|Bacteroidetes	CO	Thiol disulfide interchange protein	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
TLS3_k127_4839280_1	746697.Aeqsu_1477	1.788e-211	677.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1HX34@117743|Flavobacteriia	976|Bacteroidetes	CO	Thiol disulfide interchange protein	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
TLS3_k127_4839280_7	1250005.PHEL85_0106	4.447e-66	230.0	COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,1HY16@117743|Flavobacteriia,3VWW2@52959|Polaribacter	976|Bacteroidetes	P	Rubrerythrin	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
TLS3_k127_4839280_13	509635.N824_06940	9.368e-21	94.0	COG2919@1|root,COG2919@2|Bacteria,4NURQ@976|Bacteroidetes,1IYQM@117747|Sphingobacteriia	976|Bacteroidetes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
TLS3_k127_4839280_14	1123234.AUKI01000016_gene2953	3.212e-06	54.0	2E5JY@1|root,330B6@2|Bacteria,4NV2G@976|Bacteroidetes,1I56S@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4296)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4296
TLS3_k127_4839280_0	755732.Fluta_0895	1.622e-283	882.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1HX0U@117743|Flavobacteriia,2PAC8@246874|Cryomorphaceae	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
TLS3_k127_4839280_5	525373.HMPREF0766_11622	3.52e-90	314.0	COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,1INNI@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS3_k127_4839280_12	926562.Oweho_2768	1.754e-22	101.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,1I49T@117743|Flavobacteriia,2PB52@246874|Cryomorphaceae	976|Bacteroidetes	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
TLS3_k127_4839280_9	929713.NIASO_17770	4.205e-26	111.0	COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,1ITMU@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM membrane protein of	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
TLS3_k127_4839280_4	1313301.AUGC01000008_gene493	1.265e-183	582.0	2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4839280_8	755732.Fluta_3556	1.204e-32	138.0	29N3N@1|root,32D2M@2|Bacteria,4NRTM@976|Bacteroidetes,1ICPZ@117743|Flavobacteriia,2PBKH@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4839280_6	755732.Fluta_1335	1.072e-74	273.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia,2PBC5@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TPR_16,TPR_8
TLS3_k127_4857790_4	929556.Solca_1188	8.074e-46	179.0	COG2972@1|root,COG2972@2|Bacteria,4NHG3@976|Bacteroidetes,1INSV@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
TLS3_k127_4857790_3	929556.Solca_1187	3.004e-75	261.0	COG3279@1|root,COG3279@2|Bacteria,4NEAH@976|Bacteroidetes,1IQME@117747|Sphingobacteriia	976|Bacteroidetes	K	response regulator, receiver	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_4857790_2	269798.CHU_2272	2.512e-80	273.0	29R44@1|root,30C5C@2|Bacteria,4NN15@976|Bacteroidetes,47PN2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4857790_7	215803.DB30_0049	3.229e-07	61.0	COG1361@1|root,COG1572@1|root,COG1361@2|Bacteria,COG1572@2|Bacteria,1NWT2@1224|Proteobacteria,430ZW@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Domain of unknown function (DUF5011)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011
TLS3_k127_4857790_9	760192.Halhy_0821	0.0004845	45.0	2EDUU@1|root,2ZMNC@2|Bacteria,4P7AC@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4857790_5	1408433.JHXV01000009_gene1222	2.357e-27	119.0	COG5435@1|root,COG5435@2|Bacteria,4NYIK@976|Bacteroidetes	976|Bacteroidetes	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4857790_6	1227739.Hsw_2436	1.016e-11	68.0	COG0491@1|root,COG0491@2|Bacteria,4P569@976|Bacteroidetes,47W30@768503|Cytophagia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4857790_1	1408433.JHXV01000002_gene354	8.811e-103	349.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_3,CarboxypepD_reg,Collagen,DUF1929,Glyoxal_oxid_N,Laminin_G_3,NosD,PA14,Phage-tail_3,TIG,fn3
TLS3_k127_4857790_8	641526.ADIWIN_3076	9.166e-07	57.0	COG3637@1|root,COG3637@2|Bacteria,4NRFZ@976|Bacteroidetes,1I2XQ@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4857790_0	929556.Solca_3515	4.768e-293	908.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,1IR7B@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
TLS3_k127_4875_1	925409.KI911562_gene2863	2.289e-205	648.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1IWX4@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
TLS3_k127_4875_7	755732.Fluta_2012	5.625e-42	179.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1IG7B@117743|Flavobacteriia,2PBE8@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_4875_0	1408433.JHXV01000034_gene18	6.063e-272	859.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1HWYD@117743|Flavobacteriia,2PAG3@246874|Cryomorphaceae	976|Bacteroidetes	L	UvrD-like helicase C-terminal domain	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
TLS3_k127_4875_5	1123277.KB893172_gene848	4.468e-58	228.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47NXA@768503|Cytophagia	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Cleaved_Adhesin,PKD,Peptidase_M43,fn3
TLS3_k127_4875_2	929713.NIASO_14165	8.103e-128	413.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,1INUA@117747|Sphingobacteriia	976|Bacteroidetes	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_4875_6	1121899.Q764_12215	1.078e-49	181.0	COG5562@1|root,COG5562@2|Bacteria,4NR3A@976|Bacteroidetes,1I3BI@117743|Flavobacteriia,2NWDV@237|Flavobacterium	976|Bacteroidetes	S	Phage envelope protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1398
TLS3_k127_4875_4	616991.JPOO01000001_gene4218	1.127e-72	250.0	COG2148@1|root,COG2148@2|Bacteria,4NNHR@976|Bacteroidetes,1I2JE@117743|Flavobacteriia,23HXR@178469|Arenibacter	976|Bacteroidetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
TLS3_k127_4875_3	755732.Fluta_2193	2.547e-73	252.0	COG0399@1|root,COG0399@2|Bacteria,4NFQ8@976|Bacteroidetes,1HZBY@117743|Flavobacteriia,2PBDW@246874|Cryomorphaceae	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_4976038_0	468059.AUHA01000002_gene545	5.601e-26	125.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,1INZH@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_4984436_1	761193.Runsl_3057	3.769e-72	249.0	COG0586@1|root,COG0586@2|Bacteria,4NHQA@976|Bacteroidetes,47NAX@768503|Cytophagia	976|Bacteroidetes	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
TLS3_k127_4984436_3	269798.CHU_2634	5.502e-31	124.0	COG0607@1|root,COG0607@2|Bacteria,4NRFK@976|Bacteroidetes,47RKB@768503|Cytophagia	976|Bacteroidetes	P	Rhodanese Homology Domain	naoX	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS3_k127_4984436_0	755732.Fluta_3660	1.449e-96	323.0	COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,1IMQP@117743|Flavobacteriia,2PBFH@246874|Cryomorphaceae	976|Bacteroidetes	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
TLS3_k127_4984436_2	714943.Mucpa_3996	8.605e-38	147.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
TLS3_k127_4993996_0	1121373.KB903664_gene2645	2.029e-238	751.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,4NDXY@976|Bacteroidetes,47U9U@768503|Cytophagia	976|Bacteroidetes	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,POTRA,Patatin
TLS3_k127_4993996_1	1202532.FF52_21468	8.283e-69	241.0	COG1566@1|root,COG1566@2|Bacteria,4PKRC@976|Bacteroidetes,1IJDD@117743|Flavobacteriia,2NS5Y@237|Flavobacterium	976|Bacteroidetes	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
TLS3_k127_5028086_10	468059.AUHA01000002_gene74	2.618e-06	61.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1ITAS@117747|Sphingobacteriia	976|Bacteroidetes	O	Serine protease, subtilase family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
TLS3_k127_5028086_1	755732.Fluta_0625	1.416e-180	575.0	COG0436@1|root,COG0436@2|Bacteria,4NFPR@976|Bacteroidetes,1HY08@117743|Flavobacteriia,2PBFC@246874|Cryomorphaceae	976|Bacteroidetes	H	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_5028086_7	929556.Solca_4355	1.825e-64	228.0	COG3091@1|root,COG3091@2|Bacteria,4NDXX@976|Bacteroidetes,1IS5M@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM SprT-like family	sprT	-	-	-	-	-	-	-	-	-	-	-	SprT-like
TLS3_k127_5028086_3	1121396.KB893127_gene3791	9.173e-104	343.0	COG0171@1|root,COG0171@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2X1YR@28221|Deltaproteobacteria,2MIYF@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
TLS3_k127_5028086_9	153721.MYP_508	4.044e-10	64.0	COG0718@1|root,COG0718@2|Bacteria,4NQ37@976|Bacteroidetes,47R3V@768503|Cytophagia	976|Bacteroidetes	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
TLS3_k127_5028086_5	485918.Cpin_0426	4.674e-85	284.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,1IS18@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0663 Carbonic anhydrase acetyltransferase isoleucine patch superfamily	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
TLS3_k127_5028086_6	1107311.Q767_01620	1.175e-67	253.0	COG3291@1|root,COG3386@1|root,COG5306@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5306@2|Bacteria,4PM1B@976|Bacteroidetes	976|Bacteroidetes	G	SPTR Cell surface protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5028086_4	1453500.AT05_10620	9.128e-99	329.0	COG1024@1|root,COG1024@2|Bacteria,4NHRF@976|Bacteroidetes,1HXUI@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
TLS3_k127_5028086_2	468059.AUHA01000003_gene1959	9.135e-138	444.0	COG0010@1|root,COG0010@2|Bacteria,4NE26@976|Bacteroidetes,1IQBU@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	rocF	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS3_k127_5028086_0	445970.ALIPUT_00182	6.881e-219	687.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,2G0KY@200643|Bacteroidia	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS3_k127_5028086_8	216432.CA2559_00565	1.088e-29	118.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,1HXDD@117743|Flavobacteriia	976|Bacteroidetes	D	rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
TLS3_k127_50454_1	1453505.JASY01000001_gene3256	2.214e-116	376.0	COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes,1HXY7@117743|Flavobacteriia,2NVS1@237|Flavobacterium	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
TLS3_k127_50454_0	153721.MYP_4515	4.007e-174	553.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,47NKV@768503|Cytophagia	976|Bacteroidetes	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
TLS3_k127_5086739_1	546269.HMPREF0389_01600	2.492e-07	63.0	28KIX@1|root,2ZA44@2|Bacteria,1UYPD@1239|Firmicutes,24ATH@186801|Clostridia	186801|Clostridia	S	Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E)	phaE	-	-	-	-	-	-	-	-	-	-	-	PHA_synth_III_E
TLS3_k127_5086739_0	1408433.JHXV01000006_gene2722	1.688e-44	179.0	COG1807@1|root,COG1807@2|Bacteria,4PB0R@976|Bacteroidetes,1I8NW@117743|Flavobacteriia,2PBV3@246874|Cryomorphaceae	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5117557_3	1121904.ARBP01000002_gene7078	2.892e-14	77.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,47N1D@768503|Cytophagia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	LAB_N,PMT,PMT_2
TLS3_k127_5117557_4	1283300.ATXB01000001_gene2417	1.798e-12	71.0	2E7TI@1|root,3328N@2|Bacteria,1NCCK@1224|Proteobacteria,1SDE1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TRL-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	TRL
TLS3_k127_5117557_5	203275.BFO_2764	2.036e-08	63.0	28UNA@1|root,2ZGSU@2|Bacteria,4P98F@976|Bacteroidetes,2FVM6@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5117557_0	945713.IALB_3111	4.005e-185	588.0	COG1509@1|root,COG1509@2|Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	kamA3	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
TLS3_k127_5117557_1	1484460.JSWG01000006_gene2863	8.812e-39	154.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,1I332@117743|Flavobacteriia	976|Bacteroidetes	K	Bacterial regulatory proteins, crp family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TLS3_k127_5117557_2	1122217.KB899582_gene1540	2.638e-15	81.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1,TPR_7,WG_beta_rep
TLS3_k127_5125474_0	1313421.JHBV01000042_gene3343	4.233e-72	258.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_5133539_1	483216.BACEGG_03739	3.369e-142	456.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,2FN52@200643|Bacteroidia,4AKNF@815|Bacteroidaceae	976|Bacteroidetes	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
TLS3_k127_5133539_6	1347342.BN863_21750	0.0002771	51.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_5133539_4	1286632.P278_18170	1.383e-82	281.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,1HX5T@117743|Flavobacteriia	976|Bacteroidetes	E	Shikimate	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
TLS3_k127_5133539_0	929556.Solca_2616	8.316e-307	956.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,1IPB3@117747|Sphingobacteriia	976|Bacteroidetes	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
TLS3_k127_5133539_5	1358423.N180_18365	2.679e-41	154.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,1ISVX@117747|Sphingobacteriia	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
TLS3_k127_5133539_2	1121897.AUGO01000007_gene520	3.02e-112	368.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,1HX31@117743|Flavobacteriia,2NSNX@237|Flavobacterium	976|Bacteroidetes	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
TLS3_k127_5133539_3	865938.Weevi_1967	3.27e-85	291.0	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,1HYDH@117743|Flavobacteriia	976|Bacteroidetes	F	phosphorylase	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
TLS3_k127_5147879_0	1356852.N008_03550	7.111e-123	404.0	COG2876@1|root,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,47K32@768503|Cytophagia	976|Bacteroidetes	E	chorismate mutase	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
TLS3_k127_5147879_2	504472.Slin_5746	9.622e-52	194.0	COG3279@1|root,COG3279@2|Bacteria,4NJ3A@976|Bacteroidetes,47KQ2@768503|Cytophagia	976|Bacteroidetes	KT	PFAM LytTr DNA-binding region	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
TLS3_k127_5147879_3	1408444.JHYC01000026_gene1470	3.092e-22	105.0	2AJYR@1|root,31AMX@2|Bacteria,1QFSP@1224|Proteobacteria,1TD2M@1236|Gammaproteobacteria,1JG3G@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5147879_1	1122179.KB890430_gene4291	2.131e-77	269.0	2ASFK@1|root,31HVJ@2|Bacteria,4NQMQ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5154784_2	485918.Cpin_1318	4.518e-50	184.0	COG0476@1|root,COG0476@2|Bacteria,4NHWN@976|Bacteroidetes,1IPCC@117747|Sphingobacteriia	976|Bacteroidetes	H	UBA THIF-type NAD FAD binding	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
TLS3_k127_5154784_1	866536.Belba_3712	1.267e-50	184.0	COG3437@1|root,COG3437@2|Bacteria,4NP14@976|Bacteroidetes,47Q84@768503|Cytophagia	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,SpoIIE
TLS3_k127_5154784_0	1408433.JHXV01000001_gene653	1.926e-109	376.0	COG2885@1|root,COG3391@1|root,COG2885@2|Bacteria,COG3391@2|Bacteria,4NFM6@976|Bacteroidetes	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_5154784_4	1122225.AULQ01000012_gene410	3.161e-26	109.0	COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,1I3XI@117743|Flavobacteriia	976|Bacteroidetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
TLS3_k127_5154784_3	313606.M23134_08237	4.322e-44	176.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes,47V60@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
TLS3_k127_5154784_5	1270196.JCKI01000004_gene1105	2.818e-12	69.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1INX9@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG2270 Permease of the major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
TLS3_k127_5225734_2	445970.ALIPUT_02353	7.396e-44	163.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,22U7B@171550|Rikenellaceae	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
TLS3_k127_5225734_0	204669.Acid345_0764	4.365e-113	398.0	COG2706@1|root,COG5492@1|root,COG2706@2|Bacteria,COG5492@2|Bacteria,3Y6M8@57723|Acidobacteria,2JMGX@204432|Acidobacteriia	204432|Acidobacteriia	GN	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4
TLS3_k127_5225734_3	1121373.KB903624_gene2395	4.305e-13	83.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,47K2W@768503|Cytophagia	976|Bacteroidetes	E	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA
TLS3_k127_5225734_1	319236.JCM19294_148	3.101e-70	250.0	COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,1HXX8@117743|Flavobacteriia,3HK2H@363408|Nonlabens	976|Bacteroidetes	M	Transglycosylase SLT domain	mltD_2	-	-	-	-	-	-	-	-	-	-	-	SLT
TLS3_k127_5243432_0	743722.Sph21_1376	7.013e-116	381.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,1IP4G@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
TLS3_k127_5243432_1	1408433.JHXV01000036_gene237	3.076e-84	286.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,1HX93@117743|Flavobacteriia,2PANE@246874|Cryomorphaceae	976|Bacteroidetes	S	zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
TLS3_k127_5243432_2	880070.Cycma_2448	9.413e-24	104.0	COG2827@1|root,COG2827@2|Bacteria,4NVHC@976|Bacteroidetes,47RW6@768503|Cytophagia	976|Bacteroidetes	L	PFAM GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
TLS3_k127_5264790_0	867902.Ornrh_0829	1.163e-136	442.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,1HXZY@117743|Flavobacteriia	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TLS3_k127_5264790_1	880074.BARVI_04850	1.619e-86	293.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,2FMH1@200643|Bacteroidia,22WN1@171551|Porphyromonadaceae	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
TLS3_k127_5264790_3	1499967.BAYZ01000147_gene739	3.084e-44	163.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	MA20_27600	-	5.3.1.15	ko:K09988	ko00040,map00040	-	R01898	RC00516	ko00000,ko00001,ko01000	-	-	-	-
TLS3_k127_5264790_2	1296415.JACC01000043_gene70	7.211e-51	184.0	2BVIP@1|root,32QWT@2|Bacteria,4PKQQ@976|Bacteroidetes,1IJDA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
TLS3_k127_5272894_3	1392489.JPOL01000002_gene785	2.567e-16	80.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,1HYBN@117743|Flavobacteriia,2XIGG@283735|Leeuwenhoekiella	976|Bacteroidetes	D	TilS substrate C-terminal domain	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
TLS3_k127_5272894_1	929556.Solca_3273	8.711e-34	136.0	2A1N9@1|root,30PWI@2|Bacteria,4NPMN@976|Bacteroidetes,1ISIP@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5272894_2	1094466.KQS_08765	9.574e-31	124.0	2E46C@1|root,32Z2A@2|Bacteria,4NV81@976|Bacteroidetes,1I537@117743|Flavobacteriia,2NXAP@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5272894_0	1454007.JAUG01000009_gene2013	1.34e-46	179.0	COG4589@1|root,COG4589@2|Bacteria,4NIPM@976|Bacteroidetes,1IQW1@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
TLS3_k127_5272894_4	1041826.FCOL_03595	1.952e-12	71.0	COG2095@1|root,COG2095@2|Bacteria,4NIHF@976|Bacteroidetes,1HY3F@117743|Flavobacteriia,2NSGQ@237|Flavobacterium	976|Bacteroidetes	U	UPF0056 membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
TLS3_k127_5282311_1	929562.Emtol_1450	8.764e-131	435.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,47JYH@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
TLS3_k127_5282311_2	1408473.JHXO01000010_gene3654	6.24e-80	272.0	COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,2FN3M@200643|Bacteroidia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
TLS3_k127_5282311_0	1121889.AUDM01000008_gene751	1.39e-170	544.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HWZU@117743|Flavobacteriia,2NVHA@237|Flavobacterium	976|Bacteroidetes	I	Belongs to the thiolase family	pcaF	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
TLS3_k127_5282311_5	1121889.AUDM01000008_gene750	1.728e-41	156.0	COG2050@1|root,COG2050@2|Bacteria,4NM7W@976|Bacteroidetes,1I2P9@117743|Flavobacteriia	976|Bacteroidetes	Q	thioesterase	paaI	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
TLS3_k127_5282311_3	755732.Fluta_0132	3.644e-70	241.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,1HX1J@117743|Flavobacteriia,2PATS@246874|Cryomorphaceae	976|Bacteroidetes	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
TLS3_k127_5282311_4	1123277.KB893173_gene1823	1.55e-47	180.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,47PTI@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_5282311_6	880071.Fleli_0697	1.519e-09	62.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,47XEG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
TLS3_k127_5289177_4	762903.Pedsa_3020	3.19e-12	66.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,1IQPX@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
TLS3_k127_5289177_3	1237149.C900_02771	1.448e-50	186.0	COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,47PV2@768503|Cytophagia	976|Bacteroidetes	O	PFAM Scaffold protein Nfu NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
TLS3_k127_5289177_2	929562.Emtol_4175	2.19e-73	249.0	COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,47P6P@768503|Cytophagia	976|Bacteroidetes	F	PFAM Cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
TLS3_k127_5289177_0	1453500.AT05_08790	5.142e-246	803.0	COG1629@1|root,COG4771@2|Bacteria,4NTQD@976|Bacteroidetes	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
TLS3_k127_5289177_1	1408433.JHXV01000022_gene3142	1.089e-115	389.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5305999_2	1408433.JHXV01000029_gene3118	1.037e-12	72.0	COG3637@1|root,COG3637@2|Bacteria,4NQ11@976|Bacteroidetes	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_5305999_0	926549.KI421517_gene3965	1.967e-116	383.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,47K5N@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	ybiK	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
TLS3_k127_5305999_1	1408813.AYMG01000001_gene3408	8.018e-113	371.0	COG4242@1|root,COG4242@2|Bacteria,4NI55@976|Bacteroidetes,1IREV@117747|Sphingobacteriia	976|Bacteroidetes	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
TLS3_k127_5309734_4	983548.Krodi_1481	2.248e-29	124.0	COG2856@1|root,COG2856@2|Bacteria,4NYB2@976|Bacteroidetes	976|Bacteroidetes	E	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
TLS3_k127_5309734_7	1166018.FAES_pFAES01075	9.616e-10	64.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07075,ko:K15773	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,HTH_31
TLS3_k127_5309734_8	78245.Xaut_0777	0.0001969	49.0	2C19N@1|root,336NB@2|Bacteria,1N9YS@1224|Proteobacteria,2UGTA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5309734_5	743836.AYNA01000052_gene61	5.366e-27	115.0	2D08V@1|root,32T82@2|Bacteria,1RGTN@1224|Proteobacteria,2U7IE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5309734_3	1038866.KB902773_gene793	1.655e-31	128.0	COG1310@1|root,COG1310@2|Bacteria,1RHPM@1224|Proteobacteria,2UA3R@28211|Alphaproteobacteria,3K1FQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	metal-dependent protease of the Pad1 Jab1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
TLS3_k127_5309734_0	743836.AYNA01000052_gene63	1.111e-67	248.0	COG0476@1|root,COG0476@2|Bacteria,1NFVV@1224|Proteobacteria,2TV6X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
TLS3_k127_5309734_6	313606.M23134_01904	4.891e-18	91.0	2EFHI@1|root,339A3@2|Bacteria	2|Bacteria	S	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C70
TLS3_k127_5309734_1	153721.MYP_3287	9.465e-62	234.0	2BZPV@1|root,332ES@2|Bacteria,4NWAA@976|Bacteroidetes,47SJC@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5309734_2	1144313.PMI10_03139	1.234e-49	185.0	2BXAS@1|root,2Z9KE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5313415_9	867902.Ornrh_0947	1.026e-48	178.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,1I24B@117743|Flavobacteriia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
TLS3_k127_5313415_1	289377.HL41_01855	5.596e-188	606.0	COG0445@1|root,COG0445@2|Bacteria,2GHNC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
TLS3_k127_5313415_6	153721.MYP_1667	1.23e-82	286.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,47K52@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
TLS3_k127_5313415_7	755732.Fluta_2768	3.544e-81	274.0	COG0663@1|root,COG0663@2|Bacteria,4NG5P@976|Bacteroidetes,1HXXJ@117743|Flavobacteriia,2PAN1@246874|Cryomorphaceae	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	paaY	-	-	ko:K02617,ko:K08279	-	-	-	-	ko00000	-	-	-	Hexapep
TLS3_k127_5313415_3	391596.PBAL39_08265	2.143e-174	553.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
TLS3_k127_5313415_2	1123277.KB893195_gene5586	5.284e-177	568.0	COG0318@1|root,COG0318@2|Bacteria,4PKQG@976|Bacteroidetes,47K42@768503|Cytophagia	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
TLS3_k127_5313415_11	1150600.ADIARSV_3770	8.32e-13	76.0	COG1280@1|root,COG1280@2|Bacteria,4NH3F@976|Bacteroidetes,1IS1U@117747|Sphingobacteriia	976|Bacteroidetes	E	Lysine exporter protein (Lyse ygga)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
TLS3_k127_5313415_10	388413.ALPR1_00450	4.952e-14	75.0	COG2921@1|root,COG2921@2|Bacteria,4P9XR@976|Bacteroidetes,47S9P@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF493)	-	-	-	-	-	-	-	-	-	-	-	-	DUF493
TLS3_k127_5313415_8	944547.ABLL_1962	1.485e-59	217.0	COG2017@1|root,COG2017@2|Bacteria,1MVR4@1224|Proteobacteria,42USW@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	Aldose 1-epimerase	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
TLS3_k127_5313415_4	755732.Fluta_0357	8.735e-109	367.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,1HX7I@117743|Flavobacteriia,2PABE@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Bacterial trigger factor protein (TF)	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
TLS3_k127_5313415_5	926549.KI421517_gene387	7.698e-95	317.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,47MC0@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
TLS3_k127_5313415_0	1453500.AT05_07935	1.717e-195	633.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1HWVA@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
TLS3_k127_5321074_0	398720.MED217_09917	7.595e-169	535.0	COG1294@1|root,COG1294@2|Bacteria,4NH9P@976|Bacteroidetes,1HXNH@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome d ubiquinol oxidase, subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
TLS3_k127_5321074_1	1408473.JHXO01000007_gene784	1.197e-25	115.0	COG0457@1|root,COG0457@2|Bacteria,4NQ8Q@976|Bacteroidetes,2FQ4C@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG28004 non supervised orthologous group	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	TPR_16,TPR_8
TLS3_k127_5322839_8	1168289.AJKI01000014_gene2063	1.304e-07	63.0	2CJVV@1|root,32SAW@2|Bacteria,4NTMY@976|Bacteroidetes,2FYEY@200643|Bacteroidia,3XIXT@558415|Marinilabiliaceae	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_5322839_2	755732.Fluta_1252	1.62e-52	190.0	COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,1I1AS@117743|Flavobacteriia,2PAVR@246874|Cryomorphaceae	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
TLS3_k127_5322839_0	1094466.KQS_12880	1.249e-243	757.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1HXDC@117743|Flavobacteriia,2NTT1@237|Flavobacterium	976|Bacteroidetes	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
TLS3_k127_5322839_6	641524.ADICYQ_0517	1.384e-25	108.0	COG1669@1|root,COG2361@1|root,COG1669@2|Bacteria,COG2361@2|Bacteria,4NV8X@976|Bacteroidetes,47RWY@768503|Cytophagia	976|Bacteroidetes	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
TLS3_k127_5322839_3	641524.ADICYQ_0517	3.556e-43	160.0	COG1669@1|root,COG2361@1|root,COG1669@2|Bacteria,COG2361@2|Bacteria,4NV8X@976|Bacteroidetes,47RWY@768503|Cytophagia	976|Bacteroidetes	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
TLS3_k127_5322839_5	269798.CHU_0643	4.251e-38	144.0	COG3549@1|root,COG3549@2|Bacteria,4NSZ2@976|Bacteroidetes,47RJA@768503|Cytophagia	976|Bacteroidetes	S	PFAM Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
TLS3_k127_5322839_4	1120965.AUBV01000016_gene9	4.493e-42	156.0	COG3093@1|root,COG3093@2|Bacteria,4NSBZ@976|Bacteroidetes,47R1U@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM addiction module antidote protein, HigA family	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
TLS3_k127_5322839_7	362418.IW19_12375	4.884e-15	78.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
TLS3_k127_5322839_1	1131812.JQMS01000001_gene2028	3.224e-153	489.0	COG5002@1|root,COG5002@2|Bacteria,4PKIV@976|Bacteroidetes,1HXTU@117743|Flavobacteriia,2NU8K@237|Flavobacterium	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9
TLS3_k127_5369038_1	880526.KE386488_gene1665	1.278e-82	276.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,2FMKX@200643|Bacteroidia,22U22@171550|Rikenellaceae	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
TLS3_k127_5369038_2	1223410.KN050846_gene1025	2.474e-74	254.0	COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,1HX7M@117743|Flavobacteriia	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
TLS3_k127_5369038_5	1122179.KB890420_gene2490	2.16e-09	66.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8,YfiO
TLS3_k127_5369038_4	509635.N824_02990	2.993e-24	107.0	COG2363@1|root,COG2363@2|Bacteria,4NS8F@976|Bacteroidetes,1ITGX@117747|Sphingobacteriia	976|Bacteroidetes	S	small membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
TLS3_k127_5369038_0	755732.Fluta_3624	1.011e-256	801.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1HX6C@117743|Flavobacteriia,2PA7A@246874|Cryomorphaceae	976|Bacteroidetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
TLS3_k127_5369038_3	761193.Runsl_2894	1.146e-41	157.0	COG1943@1|root,COG1943@2|Bacteria,4NPU8@976|Bacteroidetes,47Q01@768503|Cytophagia	976|Bacteroidetes	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
TLS3_k127_5397404_1	1408473.JHXO01000004_gene166	1.723e-165	572.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,2FNBJ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location OuterMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	TamB
TLS3_k127_5397404_2	471854.Dfer_5195	8.015e-10	68.0	2BNB7@1|root,32GYU@2|Bacteria,4NQDS@976|Bacteroidetes,47R7G@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5397404_0	153721.MYP_1098	1.787e-185	603.0	COG0475@1|root,COG0475@2|Bacteria,4NF11@976|Bacteroidetes,47KD1@768503|Cytophagia	976|Bacteroidetes	P	Sodium/hydrogen exchanger family	ybaL_1	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
TLS3_k127_5432675_2	1227739.Hsw_3426	9.238e-206	659.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
TLS3_k127_5432675_15	929556.Solca_3492	2.645e-52	190.0	COG0615@1|root,COG0615@2|Bacteria,4NNKK@976|Bacteroidetes,1ISYY@117747|Sphingobacteriia	976|Bacteroidetes	IM	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like
TLS3_k127_5432675_14	925409.KI911562_gene2669	8.137e-56	208.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1ISJK@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
TLS3_k127_5432675_16	742725.HMPREF9450_00632	4.44e-47	171.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,2FSH0@200643|Bacteroidia,22UGY@171550|Rikenellaceae	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
TLS3_k127_5432675_17	1408433.JHXV01000017_gene1597	2.265e-30	130.0	2C52N@1|root,315JU@2|Bacteria,4PJRQ@976|Bacteroidetes,1IE9T@117743|Flavobacteriia,2PB34@246874|Cryomorphaceae	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_5432675_3	1288963.ADIS_0590	5.058e-197	627.0	COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,47K0W@768503|Cytophagia	976|Bacteroidetes	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2
TLS3_k127_5432675_1	1191523.MROS_0476	6.232e-210	663.0	COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yhcX	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,CN_hydrolase
TLS3_k127_5432675_4	1189612.A33Q_2465	2.642e-141	455.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,47JNM@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
TLS3_k127_5432675_13	1492737.FEM08_31800	3.601e-64	233.0	COG0628@1|root,COG0628@2|Bacteria,4NHP4@976|Bacteroidetes,1HXG6@117743|Flavobacteriia,2NVB7@237|Flavobacterium	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS3_k127_5432675_10	1506583.JQJY01000004_gene2829	7.77e-93	315.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,1HZDH@117743|Flavobacteriia,2NVMW@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
TLS3_k127_5432675_6	391598.FBBAL38_09852	2.46e-137	452.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
TLS3_k127_5432675_21	236814.IX39_10035	1.14e-07	62.0	COG3637@1|root,COG3637@2|Bacteria,4NV8Z@976|Bacteroidetes,1I5RI@117743|Flavobacteriia,3ZQUG@59732|Chryseobacterium	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_5432675_0	402612.FP0225	1.855e-225	701.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1HYHK@117743|Flavobacteriia,2NTEM@237|Flavobacterium	976|Bacteroidetes	Q	Homogentisate 1,2-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
TLS3_k127_5432675_19	1121007.AUML01000038_gene2065	2.845e-15	83.0	29VE2@1|root,30GUS@2|Bacteria,4NP29@976|Bacteroidetes,1I29M@117743|Flavobacteriia,2YKZF@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5432675_7	1168034.FH5T_16300	3.415e-131	427.0	COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,2FRHQ@200643|Bacteroidia	976|Bacteroidetes	S	Rhodanase C-terminal	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
TLS3_k127_5432675_8	1121889.AUDM01000003_gene2299	2.461e-129	420.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,1HWX0@117743|Flavobacteriia,2NT4H@237|Flavobacterium	976|Bacteroidetes	GM	NAD-dependent epimerase	ltd	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS3_k127_5432675_12	929556.Solca_4343	5.918e-78	278.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,1INMH@117747|Sphingobacteriia	976|Bacteroidetes	D	Peptidase, M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_5432675_20	471854.Dfer_3773	1.611e-11	75.0	COG2834@1|root,COG2834@2|Bacteria,4NFYQ@976|Bacteroidetes,47N94@768503|Cytophagia	976|Bacteroidetes	M	Domain of unknown function (DUF4292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
TLS3_k127_5432675_11	1168034.FH5T_07885	1.393e-83	299.0	COG0457@1|root,COG0457@2|Bacteria,4NDVW@976|Bacteroidetes,2FMY8@200643|Bacteroidia	976|Bacteroidetes	NU	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
TLS3_k127_5432675_5	926549.KI421517_gene1852	2.798e-139	450.0	COG1208@1|root,COG1208@2|Bacteria,4NE97@976|Bacteroidetes,47ND5@768503|Cytophagia	976|Bacteroidetes	JM	Nucleotidyl transferase	rffH	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
TLS3_k127_5432675_18	926562.Oweho_3286	4.58e-30	127.0	COG1514@1|root,COG1514@2|Bacteria,4NTUH@976|Bacteroidetes,1I48G@117743|Flavobacteriia	976|Bacteroidetes	J	2',5' RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
TLS3_k127_5432675_9	1358423.N180_07170	1.606e-98	326.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,1ISIA@117747|Sphingobacteriia	976|Bacteroidetes	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
TLS3_k127_5442889_20	1122165.AUHS01000016_gene85	3.798e-13	70.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,1JEAF@118969|Legionellales	118969|Legionellales	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
TLS3_k127_5442889_12	709991.Odosp_0657	3.053e-42	160.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,2FM82@200643|Bacteroidia,22YAY@171551|Porphyromonadaceae	976|Bacteroidetes	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
TLS3_k127_5442889_19	1178825.ALIH01000015_gene1900	3.283e-15	78.0	2E77J@1|root,331RB@2|Bacteria,4NW0U@976|Bacteroidetes,1I5GK@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5442889_1	929556.Solca_1166	9.081e-234	731.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,1IQ95@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase, family M20 M25 M40	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_5442889_21	945713.IALB_1831	1.241e-10	73.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9
TLS3_k127_5442889_16	1346330.M472_07525	5.433e-30	123.0	COG1188@1|root,COG1188@2|Bacteria,4NP8I@976|Bacteroidetes,1ISBI@117747|Sphingobacteriia	976|Bacteroidetes	J	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
TLS3_k127_5442889_15	313606.M23134_07627	3.397e-31	131.0	2CWY1@1|root,32T0M@2|Bacteria,4P319@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5442889_6	1406840.Q763_14335	7.23e-117	384.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,1IC39@117743|Flavobacteriia,2NY56@237|Flavobacterium	976|Bacteroidetes	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
TLS3_k127_5442889_0	1123248.KB893386_gene1917	0.0	1039.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1IR88@117747|Sphingobacteriia	976|Bacteroidetes	P	TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
TLS3_k127_5442889_2	616991.JPOO01000003_gene2088	3.382e-223	706.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1HWQN@117743|Flavobacteriia,23GQH@178469|Arenibacter	976|Bacteroidetes	L	UvrC Helix-hairpin-helix N-terminal	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
TLS3_k127_5442889_7	1121373.KB903632_gene542	4.246e-101	345.0	COG1134@1|root,COG1134@2|Bacteria,4NEDM@976|Bacteroidetes,47JN7@768503|Cytophagia	976|Bacteroidetes	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
TLS3_k127_5442889_4	1127695.HMPREF9163_00572	1.741e-126	414.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4H2HH@909932|Negativicutes	909932|Negativicutes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_5442889_11	1321786.HMPREF1992_00161	9.218e-57	210.0	COG0451@1|root,COG0451@2|Bacteria,1TQV2@1239|Firmicutes,4H3PX@909932|Negativicutes	909932|Negativicutes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
TLS3_k127_5442889_14	1209072.ALBT01000028_gene1289	2.467e-31	130.0	COG0110@1|root,COG0110@2|Bacteria,1RFAC@1224|Proteobacteria,1S4U0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	acetyltransferase, isoleucine patch superfamily	vioB	-	2.3.1.209	ko:K21379	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
TLS3_k127_5442889_22	1122927.KB895426_gene281	8.661e-10	69.0	COG1216@1|root,COG1216@2|Bacteria,1V5RV@1239|Firmicutes,4HIMX@91061|Bacilli,26TUK@186822|Paenibacillaceae	91061|Bacilli	S	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_5442889_18	247634.GPB2148_2248	3.115e-20	98.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,FrhB_FdhB_C,FrhB_FdhB_N,Hexapep,Hexapep_2
TLS3_k127_5442889_23	1341181.FLJC2902T_19650	3.991e-08	65.0	COG0438@1|root,COG0438@2|Bacteria,4NIV3@976|Bacteroidetes,1HZWN@117743|Flavobacteriia,2NTZ8@237|Flavobacterium	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_5442889_17	489825.LYNGBM3L_52710	3.926e-21	103.0	COG2518@1|root,COG2518@2|Bacteria,1GR78@1117|Cyanobacteria,1HE58@1150|Oscillatoriales	1117|Cyanobacteria	O	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,Methyltransf_21
TLS3_k127_5442889_10	1313301.AUGC01000003_gene2007	8.61e-65	232.0	COG1215@1|root,COG1215@2|Bacteria,4NIMF@976|Bacteroidetes	976|Bacteroidetes	M	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_5442889_8	880071.Fleli_3085	1.296e-86	301.0	COG0438@1|root,COG0438@2|Bacteria,4NG0D@976|Bacteroidetes,47RHW@768503|Cytophagia	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_5442889_9	643867.Ftrac_2414	2.164e-66	243.0	28ICP@1|root,2Z8EZ@2|Bacteria,4NKKI@976|Bacteroidetes,47N2N@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5442889_5	1121904.ARBP01000001_gene5958	2.548e-119	392.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,47JM5@768503|Cytophagia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
TLS3_k127_5442889_3	1123277.KB893199_gene4393	1.076e-132	430.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,47KPU@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
TLS3_k127_5442889_13	1034807.FBFL15_1356	2.137e-34	139.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia,2NUEE@237|Flavobacterium	976|Bacteroidetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
TLS3_k127_5445562_0	525373.HMPREF0766_13562	1.646e-121	408.0	COG1480@1|root,COG1480@2|Bacteria,4NEHV@976|Bacteroidetes,1IPKB@117747|Sphingobacteriia	976|Bacteroidetes	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
TLS3_k127_5445562_1	1408433.JHXV01000044_gene3183	2.455e-54	199.0	COG1596@1|root,COG1596@2|Bacteria,4NPJB@976|Bacteroidetes,1ICQF@117743|Flavobacteriia,2PBRF@246874|Cryomorphaceae	976|Bacteroidetes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export
TLS3_k127_5445562_2	1408433.JHXV01000044_gene3184	3.706e-36	151.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia,2PA6D@246874|Cryomorphaceae	976|Bacteroidetes	DM	Chain length determinant protein	wzc	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
TLS3_k127_5453905_3	929703.KE386491_gene371	1.083e-43	171.0	COG4485@1|root,COG4485@2|Bacteria,4NUQF@976|Bacteroidetes	976|Bacteroidetes	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
TLS3_k127_5453905_0	755732.Fluta_1214	2.758e-207	649.0	COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,1HXPE@117743|Flavobacteriia,2PA8D@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Cys Met metabolism PLP-dependent enzyme	metC	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
TLS3_k127_5453905_2	1123248.KB893348_gene193	3.472e-48	178.0	COG2353@1|root,COG2353@2|Bacteria,4NI82@976|Bacteroidetes,1IXPV@117747|Sphingobacteriia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_5453905_1	313606.M23134_07246	2.619e-107	388.0	COG2203@1|root,COG2208@1|root,COG3292@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3292@2|Bacteria,4NKGA@976|Bacteroidetes,47TQU@768503|Cytophagia	976|Bacteroidetes	T	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,SpoIIE,Y_Y_Y
TLS3_k127_5459579_4	1094466.KQS_02085	6.09e-40	151.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,1HWZA@117743|Flavobacteriia,2NSTU@237|Flavobacterium	976|Bacteroidetes	S	Flavin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
TLS3_k127_5459579_0	1168034.FH5T_21195	2.171e-220	710.0	COG1629@1|root,COG1629@2|Bacteria,4NFFN@976|Bacteroidetes,2G3GJ@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
TLS3_k127_5459579_1	929556.Solca_2054	2.379e-182	589.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,1IPAP@117747|Sphingobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
TLS3_k127_5459579_2	388413.ALPR1_12985	2.342e-94	313.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,47N3P@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
TLS3_k127_5459579_5	1178825.ALIH01000012_gene1845	6.863e-18	94.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,4NIM1@976|Bacteroidetes,1I0WD@117743|Flavobacteriia	976|Bacteroidetes	E	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Peptidase_M43,Reprolysin_3
TLS3_k127_5459579_3	1122176.KB903587_gene4507	2.468e-43	181.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1IXHT@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_5460052_13	1453500.AT05_04310	5.767e-24	113.0	COG1404@1|root,COG3291@1|root,COG3420@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3420@2|Bacteria,4NJQN@976|Bacteroidetes,1I7QH@117743|Flavobacteriia	976|Bacteroidetes	O	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,IgGFc_binding,PKD,SprB,fn3
TLS3_k127_5460052_8	1237149.C900_03219	5.971e-70	240.0	COG0662@1|root,COG0662@2|Bacteria,4NFU2@976|Bacteroidetes,47PIW@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
TLS3_k127_5460052_2	1123248.KB893331_gene3805	5.495e-168	533.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,1IQCT@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
TLS3_k127_5460052_9	1356852.N008_07605	2.942e-62	224.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,47MRR@768503|Cytophagia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_5460052_11	1506583.JQJY01000002_gene1351	5.414e-38	148.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,1HYAI@117743|Flavobacteriia,2NW0E@237|Flavobacterium	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
TLS3_k127_5460052_10	743722.Sph21_3306	1.329e-40	151.0	COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,1IT8M@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
TLS3_k127_5460052_0	1120965.AUBV01000003_gene325	1.808e-188	597.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,47JAB@768503|Cytophagia	976|Bacteroidetes	J	tRNA synthetase class II core domain (G, H, P, S and T)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
TLS3_k127_5460052_12	1296415.JACC01000066_gene2560	6.029e-36	140.0	COG0319@1|root,COG0319@2|Bacteria,4NS93@976|Bacteroidetes,1I2W7@117743|Flavobacteriia,2YJCR@290174|Aquimarina	976|Bacteroidetes	S	Uncharacterized protein family UPF0054	ybeY	-	-	-	-	-	-	-	-	-	-	-	UPF0054
TLS3_k127_5460052_14	1358423.N180_19825	8.778e-17	90.0	COG0810@1|root,COG0810@2|Bacteria,4NWK2@976|Bacteroidetes,1IWQC@117747|Sphingobacteriia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_5460052_1	313606.M23134_08061	2.256e-178	588.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,47M4H@768503|Cytophagia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_5460052_4	153721.MYP_305	1.693e-99	329.0	COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,47KEV@768503|Cytophagia	976|Bacteroidetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
TLS3_k127_5460052_5	929556.Solca_4429	7.907e-85	289.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,1IPC6@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
TLS3_k127_5460052_7	926556.Echvi_0142	3.72e-74	253.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,47PDT@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
TLS3_k127_5460052_6	926562.Oweho_3347	2.103e-79	282.0	COG1368@1|root,COG1368@2|Bacteria,4PKS4@976|Bacteroidetes,1IMND@117743|Flavobacteriia	976|Bacteroidetes	M	Doxx family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
TLS3_k127_5460052_3	755732.Fluta_0832	4.006e-119	388.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1HX6Z@117743|Flavobacteriia,2PADA@246874|Cryomorphaceae	976|Bacteroidetes	I	PFAM Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_5460125_3	1121870.AUAA01000045_gene2930	1.119e-48	179.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1HX5B@117743|Flavobacteriia,3HI03@358033|Chryseobacterium	976|Bacteroidetes	C	Oxidoreductase NAD-binding domain	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
TLS3_k127_5460125_0	1090320.KB900605_gene3040	7.539e-147	470.0	COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,2TTC4@28211|Alphaproteobacteria,2K27K@204457|Sphingomonadales	204457|Sphingomonadales	S	Phenylacetic acid catabolic protein	-	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
TLS3_k127_5460125_4	1238182.C882_4043	2.978e-37	141.0	COG3460@1|root,COG3460@2|Bacteria,1RHM5@1224|Proteobacteria,2U9HF@28211|Alphaproteobacteria,2JTQE@204441|Rhodospirillales	204441|Rhodospirillales	Q	Phenylacetic acid degradation B	-	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
TLS3_k127_5460125_1	1366050.N234_31255	3.187e-73	254.0	COG3396@1|root,COG3396@2|Bacteria,1MVYQ@1224|Proteobacteria,2VJ03@28216|Betaproteobacteria,1KCNR@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Phenylacetic acid degradation	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
TLS3_k127_5460125_2	926562.Oweho_2261	3.073e-63	220.0	COG2151@1|root,COG3677@1|root,COG2151@2|Bacteria,COG3677@2|Bacteria,4NMS0@976|Bacteroidetes,1HXIB@117743|Flavobacteriia,2PB0A@246874|Cryomorphaceae	976|Bacteroidetes	L	Pfam:DUF59	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
TLS3_k127_5460125_5	643867.Ftrac_0904	1.164e-21	111.0	COG2911@1|root,COG2911@2|Bacteria,4NKIP@976|Bacteroidetes,47YDC@768503|Cytophagia	976|Bacteroidetes	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,Gal_Lectin
TLS3_k127_5461947_3	1185876.BN8_01631	4.184e-25	106.0	COG4628@1|root,COG4628@2|Bacteria,4NUS1@976|Bacteroidetes,47RWW@768503|Cytophagia	976|Bacteroidetes	S	conserved protein (DUF2132)	-	-	-	-	-	-	-	-	-	-	-	-	VF530
TLS3_k127_5461947_2	929703.KE386491_gene510	4.215e-31	126.0	COG3118@1|root,COG3118@2|Bacteria,4NSE6@976|Bacteroidetes,47R3Q@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM bacillithiol system protein YtxJ	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
TLS3_k127_5461947_1	1094466.KQS_03850	6.22e-55	198.0	2DC7W@1|root,2ZD7C@2|Bacteria,4NMMW@976|Bacteroidetes,1I1HS@117743|Flavobacteriia,2NUHA@237|Flavobacterium	976|Bacteroidetes	M	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
TLS3_k127_5461947_0	1341155.FSS13T_26930	1.269e-149	478.0	COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,1HWPD@117743|Flavobacteriia,2NSQQ@237|Flavobacterium	976|Bacteroidetes	E	Tryptophan 2,3-dioxygenase	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
TLS3_k127_5475779_3	643867.Ftrac_1098	4.367e-06	48.0	2EX4T@1|root,33QFU@2|Bacteria,4P0AC@976|Bacteroidetes,47TMJ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5475779_2	1237149.C900_02393	2.849e-40	160.0	2AFYA@1|root,31622@2|Bacteria,4P4XX@976|Bacteroidetes,47VB7@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1571)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1571,LysM
TLS3_k127_5475779_1	761193.Runsl_3684	1.149e-88	299.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,47M2Z@768503|Cytophagia	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
TLS3_k127_5475779_0	925409.KI911562_gene115	2.659e-125	413.0	COG0809@1|root,COG0809@2|Bacteria,4NDZ5@976|Bacteroidetes,1IWHH@117747|Sphingobacteriia	976|Bacteroidetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
TLS3_k127_5478108_1	1131812.JQMS01000001_gene2249	7.624e-08	63.0	28JIP@1|root,2Z82C@2|Bacteria,4NFN9@976|Bacteroidetes,1HZ0J@117743|Flavobacteriia,2NXD6@237|Flavobacterium	976|Bacteroidetes	S	S1/P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease
TLS3_k127_5478108_0	1237149.C900_03759	4.352e-70	248.0	COG2202@1|root,COG2203@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,4NIXZ@976|Bacteroidetes,47MCW@768503|Cytophagia	976|Bacteroidetes	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,PAS,PAS_4,PAS_9,SpoIIE
TLS3_k127_5479267_0	1178825.ALIH01000013_gene557	1.11e-93	313.0	COG1974@1|root,COG1974@2|Bacteria,4PKQ7@976|Bacteroidetes,1IJGW@117743|Flavobacteriia	976|Bacteroidetes	K	XRE family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
TLS3_k127_5479267_1	1121896.JMLU01000003_gene2194	1.347e-40	174.0	COG1357@1|root,COG3291@1|root,COG4935@1|root,COG1357@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZC@976|Bacteroidetes,1I0G4@117743|Flavobacteriia,2NT7Y@237|Flavobacterium	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CHU_C,He_PIG,fn3
TLS3_k127_5547532_0	1237149.C900_02782	1.357e-151	490.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,47K4Z@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
TLS3_k127_5556_2	28115.HR11_09755	2.67e-10	62.0	COG1541@1|root,COG1541@2|Bacteria,4NFRI@976|Bacteroidetes,2FMJX@200643|Bacteroidia,22WCF@171551|Porphyromonadaceae	976|Bacteroidetes	H	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
TLS3_k127_5556_0	929556.Solca_3842	2.772e-163	542.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1J0XD@117747|Sphingobacteriia	976|Bacteroidetes	D	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
TLS3_k127_5557920_1	743722.Sph21_5155	3.326e-48	181.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,1IRTD@117747|Sphingobacteriia	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
TLS3_k127_5557920_0	1406840.Q763_14180	2.28e-136	441.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1HXYP@117743|Flavobacteriia,2NSBZ@237|Flavobacterium	976|Bacteroidetes	EF	Catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
TLS3_k127_5573111_2	1408433.JHXV01000033_gene1155	7.5e-35	152.0	COG0419@1|root,COG1196@1|root,COG3391@1|root,COG0419@2|Bacteria,COG1196@2|Bacteria,COG3391@2|Bacteria,4PP0U@976|Bacteroidetes,1ICPT@117743|Flavobacteriia,2PBJT@246874|Cryomorphaceae	976|Bacteroidetes	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5573111_3	565045.NOR51B_964	2.971e-22	114.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,DUF4157,PMT_2,WD40
TLS3_k127_5573111_1	1408433.JHXV01000011_gene2054	2.024e-67	261.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IJY5@117743|Flavobacteriia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gly_rich,HYR,Laminin_G_3,PKD,SprB
TLS3_k127_5573111_0	1408433.JHXV01000002_gene420	1.641e-266	833.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,1HX8U@117743|Flavobacteriia,2PAJ8@246874|Cryomorphaceae	976|Bacteroidetes	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
TLS3_k127_5573111_5	1408433.JHXV01000017_gene1558	1.341e-05	57.0	COG3291@1|root,COG3291@2|Bacteria,4NI4A@976|Bacteroidetes,1I0P7@117743|Flavobacteriia,2PBKJ@246874|Cryomorphaceae	976|Bacteroidetes	O	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Cleaved_Adhesin,MAM,PKD,fn3
TLS3_k127_5573111_4	1121889.AUDM01000027_gene15	6.222e-11	74.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,Collagen_bind,DUF11,SdrD_B
TLS3_k127_5631948_4	1233951.IO90_06215	2.991e-29	123.0	COG4680@1|root,COG4680@2|Bacteria,4NQ54@976|Bacteroidetes,1I2RY@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
TLS3_k127_5631948_3	95619.PM1_0209575	1.497e-31	127.0	COG5499@1|root,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria,1S4IJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
TLS3_k127_5631948_2	1408433.JHXV01000029_gene3101	9.978e-40	153.0	COG4083@1|root,COG4083@2|Bacteria,4P9XV@976|Bacteroidetes,1IM56@117743|Flavobacteriia,2PC15@246874|Cryomorphaceae	976|Bacteroidetes	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
TLS3_k127_5631948_0	1279009.ADICEAN_00490	1.96e-214	673.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,47JWG@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
TLS3_k127_5631948_7	1535422.ND16A_1472	2.125e-06	55.0	COG1396@1|root,COG1396@2|Bacteria,1RF9Y@1224|Proteobacteria,1S5DN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
TLS3_k127_5631948_5	313628.LNTAR_05021	3.538e-15	89.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	YadA_stalk
TLS3_k127_5631948_8	558152.IQ37_07440	0.0001992	49.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,1HX9D@117743|Flavobacteriia,3ZPFB@59732|Chryseobacterium	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
TLS3_k127_5631948_1	1235788.C802_00363	5.413e-104	385.0	COG3209@1|root,COG3209@2|Bacteria,4NGJF@976|Bacteroidetes,2FQPQ@200643|Bacteroidia,4AQCJ@815|Bacteroidaceae	976|Bacteroidetes	M	RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,Ribonuclease,SpvB,TcdB_toxin_midN,VCBS
TLS3_k127_5658022_5	1267211.KI669560_gene1958	8.185e-12	66.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1IZWB@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
TLS3_k127_5658022_3	755732.Fluta_0716	2.549e-50	193.0	COG1835@1|root,COG1835@2|Bacteria,4PIH2@976|Bacteroidetes,1IGD6@117743|Flavobacteriia,2PBU2@246874|Cryomorphaceae	2|Bacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS3_k127_5658022_1	1107311.Q767_07760	1.523e-84	285.0	COG2085@1|root,COG2085@2|Bacteria,4NPSZ@976|Bacteroidetes,1ICXS@117743|Flavobacteriia,2NVZG@237|Flavobacterium	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
TLS3_k127_5658022_4	1131812.JQMS01000001_gene214	7.701e-19	97.0	2A7VE@1|root,30WUS@2|Bacteria,4PA7S@976|Bacteroidetes,1IDUX@117743|Flavobacteriia,2NZ9K@237|Flavobacterium	976|Bacteroidetes	S	CHAD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
TLS3_k127_5658022_2	1178825.ALIH01000002_gene909	6.932e-79	271.0	COG2135@1|root,COG2135@2|Bacteria,4NI3T@976|Bacteroidetes,1HWW1@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
TLS3_k127_5658022_0	755732.Fluta_0800	7.775e-113	388.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,1HX7Z@117743|Flavobacteriia,2PAQ0@246874|Cryomorphaceae	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
TLS3_k127_5667428_0	1121481.AUAS01000011_gene5150	8.459e-151	485.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,47U25@768503|Cytophagia	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.23	ko:K13019	ko00520,map00520	-	R09600	RC00290	ko00000,ko00001,ko01000,ko01005	-	-	-	Epimerase_2
TLS3_k127_5667428_5	1089547.KB913013_gene2979	2.153e-67	241.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,47MUX@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_5667428_3	269798.CHU_1710	2.542e-99	343.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
TLS3_k127_5667428_1	153721.MYP_2331	1.419e-134	473.0	COG2755@1|root,COG3291@1|root,COG2755@2|Bacteria,COG3291@2|Bacteria,4PHTU@976|Bacteroidetes,47P4N@768503|Cytophagia	976|Bacteroidetes	E	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_5667428_6	929556.Solca_0885	4.904e-36	145.0	COG1051@1|root,COG1051@2|Bacteria,4NS9I@976|Bacteroidetes,1ITRK@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_5667428_4	755732.Fluta_2667	4.932e-85	287.0	COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,1HXXU@117743|Flavobacteriia,2PANI@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10,4.1.1.23	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
TLS3_k127_5667428_9	886379.AEWI01000005_gene921	2.508e-13	75.0	COG3427@1|root,COG3427@2|Bacteria,4NUYJ@976|Bacteroidetes,2FS4N@200643|Bacteroidia,3XK9I@558415|Marinilabiliaceae	976|Bacteroidetes	S	Polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_5667428_8	1168034.FH5T_13840	2.177e-15	79.0	COG0011@1|root,COG0011@2|Bacteria	2|Bacteria	H	TIGRFAM Protein of	M1-594	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
TLS3_k127_5667428_7	1121957.ATVL01000006_gene2693	1.033e-29	123.0	COG2050@1|root,COG2050@2|Bacteria,4NUYW@976|Bacteroidetes,47VEA@768503|Cytophagia	976|Bacteroidetes	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
TLS3_k127_5667428_2	929713.NIASO_00720	8.145e-100	328.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,1INYW@117747|Sphingobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
TLS3_k127_5671551_10	763034.HMPREF9446_01933	3.605e-11	67.0	COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TPR_16,TPR_2,TPR_8
TLS3_k127_5671551_6	1048983.EL17_04245	9.233e-71	249.0	COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes,47MB0@768503|Cytophagia	976|Bacteroidetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
TLS3_k127_5671551_7	1380384.JADN01000004_gene2020	2.703e-45	171.0	COG1845@1|root,COG1845@2|Bacteria,4NFA7@976|Bacteroidetes,1I1D8@117743|Flavobacteriia	976|Bacteroidetes	C	Heme copper-type cytochrome quinol oxidase subunit 3	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
TLS3_k127_5671551_5	643867.Ftrac_3697	5.816e-91	305.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,47JVP@768503|Cytophagia	976|Bacteroidetes	C	cytochrome c oxidase subunit III	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
TLS3_k127_5671551_11	485918.Cpin_0518	3.612e-10	66.0	COG5605@1|root,COG5605@2|Bacteria,4PGS2@976|Bacteroidetes,1IU6V@117747|Sphingobacteriia	976|Bacteroidetes	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
TLS3_k127_5671551_3	999419.HMPREF1077_00941	4.238e-118	397.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,2FQ4K@200643|Bacteroidia,22W49@171551|Porphyromonadaceae	976|Bacteroidetes	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
TLS3_k127_5671551_1	485918.Cpin_1945	5.908e-241	761.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1IPID@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
TLS3_k127_5671551_0	762903.Pedsa_0857	7.906e-281	887.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1INVI@117747|Sphingobacteriia	976|Bacteroidetes	D	DNA segregation ATPase FtsK SpoIIIE and related	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
TLS3_k127_5671551_8	1454007.JAUG01000044_gene607	1.99e-31	132.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,1ISAH@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
TLS3_k127_5671551_4	1408433.JHXV01000010_gene527	1.244e-105	381.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4PPWM@976|Bacteroidetes,1IKWE@117743|Flavobacteriia,2PBIK@246874|Cryomorphaceae	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	srrB	-	-	-	-	-	-	-	-	-	-	-	CBS,HAMP,SpoIIE,dCache_1
TLS3_k127_5671551_12	755732.Fluta_1716	1.03e-07	67.0	COG3391@1|root,COG3391@2|Bacteria,4NGDH@976|Bacteroidetes,1HXIC@117743|Flavobacteriia,2PA7B@246874|Cryomorphaceae	976|Bacteroidetes	O	alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Calx-beta,LVIVD
TLS3_k127_5671551_2	1313421.JHBV01000029_gene2024	1.143e-118	434.0	COG3291@1|root,COG3391@1|root,COG4409@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4409@2|Bacteria,4PPK0@976|Bacteroidetes	976|Bacteroidetes	G	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5671551_13	1408433.JHXV01000026_gene3013	2.771e-06	63.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
TLS3_k127_5671551_9	926566.Terro_2525	6.968e-30	141.0	COG2133@1|root,COG2373@1|root,COG3391@1|root,COG2133@2|Bacteria,COG2373@2|Bacteria,COG3391@2|Bacteria,3Y49I@57723|Acidobacteria,2JI4I@204432|Acidobacteriia	204432|Acidobacteriia	G	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,VCBS
TLS3_k127_5689518_0	1168034.FH5T_04310	8.367e-97	325.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,2FWBI@200643|Bacteroidia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_5689518_1	1313421.JHBV01000005_gene4509	1.765e-90	324.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPTT@117747|Sphingobacteriia	976|Bacteroidetes	M	OmpA MotB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
TLS3_k127_5689518_2	1122176.KB903531_gene2997	3.751e-35	147.0	COG2067@1|root,COG2067@2|Bacteria,4PN73@976|Bacteroidetes,1IYCH@117747|Sphingobacteriia	976|Bacteroidetes	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_5708288_7	926562.Oweho_3113	5.57e-55	211.0	COG1807@1|root,COG1807@2|Bacteria,4P3XI@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_5708288_9	1086011.HJ01_02587	1.299e-18	98.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1HZEJ@117743|Flavobacteriia,2P02I@237|Flavobacterium	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
TLS3_k127_5708288_2	762903.Pedsa_1460	0.0	1013.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1IQMU@117747|Sphingobacteriia	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
TLS3_k127_5708288_11	1453505.JASY01000001_gene3389	2.94e-08	63.0	COG1520@1|root,COG4886@1|root,COG1520@2|Bacteria,COG4886@2|Bacteria,4NNUN@976|Bacteroidetes,1IKME@117743|Flavobacteriia,2NXAD@237|Flavobacterium	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,SBBP
TLS3_k127_5708288_1	1341181.FLJC2902T_28230	0.0	1112.0	COG0265@1|root,COG3291@1|root,COG4675@1|root,COG0265@2|Bacteria,COG3291@2|Bacteria,COG4675@2|Bacteria,4PNUK@976|Bacteroidetes,1IKEA@117743|Flavobacteriia,2P0S7@237|Flavobacterium	976|Bacteroidetes	O	Peptide-N-glycosidase F, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,N-glycanase_C
TLS3_k127_5708288_0	1237149.C900_02686	0.0	1176.0	COG1643@1|root,COG1643@2|Bacteria,4NFJ7@976|Bacteroidetes,47KRZ@768503|Cytophagia	976|Bacteroidetes	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
TLS3_k127_5708288_5	485918.Cpin_1896	9.413e-89	310.0	COG2010@1|root,COG2010@2|Bacteria,4NEEJ@976|Bacteroidetes,1IP2H@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,FlgD_ig
TLS3_k127_5708288_6	762903.Pedsa_2614	5.465e-56	203.0	COG2322@1|root,COG2322@2|Bacteria,4NM5N@976|Bacteroidetes,1ISQD@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF420)	yozB	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
TLS3_k127_5708288_3	1267211.KI669560_gene1210	3.485e-141	452.0	COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,1INTX@117747|Sphingobacteriia	976|Bacteroidetes	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_5708288_10	1121957.ATVL01000010_gene273	6.788e-09	65.0	2EFGG@1|root,33995@2|Bacteria,4NVDG@976|Bacteroidetes,47WZI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5708288_4	1250232.JQNJ01000001_gene3624	8.083e-136	451.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1HXTJ@117743|Flavobacteriia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
TLS3_k127_5708288_8	1408433.JHXV01000010_gene548	4.567e-54	192.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1HWSN@117743|Flavobacteriia,2PBB2@246874|Cryomorphaceae	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS3_k127_5722990_2	1341155.FSS13T_16990	2.923e-135	438.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1HWJD@117743|Flavobacteriia,2NTR4@237|Flavobacterium	976|Bacteroidetes	I	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
TLS3_k127_5722990_6	1492737.FEM08_26310	3.373e-90	302.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1HWWB@117743|Flavobacteriia,2NSSS@237|Flavobacterium	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
TLS3_k127_5722990_16	244581.IM40_01185	4.68e-12	70.0	COG0494@1|root,COG0494@2|Bacteria,1N317@1224|Proteobacteria,2UDZ1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	nUDIX hydrolase	yffH	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5722990_7	313606.M23134_06222	9.84e-68	239.0	COG2267@1|root,COG2267@2|Bacteria,4NK80@976|Bacteroidetes,47NWA@768503|Cytophagia	976|Bacteroidetes	I	Ndr family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_5722990_4	1223410.KN050846_gene1651	4.348e-100	335.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,1HXC6@117743|Flavobacteriia	976|Bacteroidetes	V	proteins, homologs of microcin C7 resistance protein MccF	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
TLS3_k127_5722990_13	1286632.P278_31580	6.979e-25	115.0	2AFQQ@1|root,315SK@2|Bacteria,4NJD4@976|Bacteroidetes,1HWPU@117743|Flavobacteriia	976|Bacteroidetes	S	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3,NUMOD4
TLS3_k127_5722990_0	468059.AUHA01000002_gene889	5.607e-311	965.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1IPA1@117747|Sphingobacteriia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
TLS3_k127_5722990_15	1237149.C900_03842	4.179e-17	93.0	2EHJH@1|root,32W49@2|Bacteria,4NTI9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5722990_5	755732.Fluta_1156	2.546e-95	320.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1HX6V@117743|Flavobacteriia,2PABW@246874|Cryomorphaceae	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
TLS3_k127_5722990_1	509635.N824_08710	1.373e-290	897.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1IP4E@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
TLS3_k127_5722990_10	643867.Ftrac_2570	1.153e-35	141.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,47QGS@768503|Cytophagia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
TLS3_k127_5722990_9	865937.Gilli_2136	7.56e-47	173.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1I239@117743|Flavobacteriia,2P6QV@244698|Gillisia	976|Bacteroidetes	C	ATP synthase B/B' CF(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
TLS3_k127_5722990_14	992406.RIA_1856	1.576e-22	98.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,1I53G@117743|Flavobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
TLS3_k127_5722990_3	929556.Solca_3297	2.057e-116	387.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1IPTF@117747|Sphingobacteriia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
TLS3_k127_5722990_8	1121373.KB903620_gene1984	6.061e-54	194.0	COG2947@1|root,COG2947@2|Bacteria,4NNQG@976|Bacteroidetes,47QAF@768503|Cytophagia	976|Bacteroidetes	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
TLS3_k127_5722990_11	1124780.ANNU01000005_gene2441	3.31e-32	132.0	COG3172@1|root,COG3172@2|Bacteria,4NFNZ@976|Bacteroidetes,47QMU@768503|Cytophagia	976|Bacteroidetes	H	ATPase kinase involved in NAD metabolism	nadR	-	-	-	-	-	-	-	-	-	-	-	AAA_28
TLS3_k127_5722990_12	861299.J421_0752	4.068e-28	120.0	COG3201@1|root,COG3201@2|Bacteria,1ZTRP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Nicotinamide mononucleotide transporter	-	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
TLS3_k127_5729990_0	1380384.JADN01000007_gene1690	3.777e-155	500.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
TLS3_k127_5731657_1	485918.Cpin_0547	7.4e-34	136.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPTT@117747|Sphingobacteriia	976|Bacteroidetes	M	OmpA MotB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573,OmpA,PD40
TLS3_k127_5731657_2	1227739.Hsw_2076	1.999e-24	111.0	COG2802@1|root,COG2802@2|Bacteria,4NEJU@976|Bacteroidetes,47NJ0@768503|Cytophagia	976|Bacteroidetes	S	Peptidase S16, lon domain protein	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
TLS3_k127_5731657_0	755732.Fluta_3396	1.292e-48	185.0	COG3637@1|root,COG3637@2|Bacteria,4PJ16@976|Bacteroidetes,1ICQ3@117743|Flavobacteriia,2PBMQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5736034_2	525373.HMPREF0766_10272	1.048e-09	70.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1IWKE@117747|Sphingobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,SPOR
TLS3_k127_5736880_3	1521187.JPIM01000041_gene572	0.0001147	45.0	COG0318@1|root,COG0318@2|Bacteria,2G7N1@200795|Chloroflexi,37718@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_5736880_2	586413.CCDL010000003_gene3180	6.756e-11	70.0	COG1670@1|root,COG1670@2|Bacteria,1V8I0@1239|Firmicutes,4HJY3@91061|Bacilli,23M58@182709|Oceanobacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	speG	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
TLS3_k127_5736880_1	445961.IW15_00470	8.419e-113	372.0	COG0463@1|root,COG0463@2|Bacteria,4NGGM@976|Bacteroidetes,1I03U@117743|Flavobacteriia,3ZNR0@59732|Chryseobacterium	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
TLS3_k127_5736880_0	468059.AUHA01000002_gene166	1.741e-140	460.0	COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes,1IRBF@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
TLS3_k127_5751660_8	760192.Halhy_2977	5.921e-23	101.0	COG0010@1|root,COG0010@2|Bacteria,4NEFA@976|Bacteroidetes,1IRUU@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	hutG	-	3.5.3.7,3.5.3.8	ko:K01479,ko:K12255	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045	R01990,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS3_k127_5751660_0	1313421.JHBV01000023_gene5147	1.978e-131	432.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1IRDA@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
TLS3_k127_5751660_5	1122176.KB903561_gene3589	2.739e-54	198.0	COG2010@1|root,COG2010@2|Bacteria,4PEWN@976|Bacteroidetes,1IXW6@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
TLS3_k127_5751660_3	1121373.KB903642_gene3696	1.201e-71	252.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47NZ9@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5751660_11	1237149.C900_04948	0.0002437	51.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,Peptidase_M43,fn3
TLS3_k127_5751660_4	1453500.AT05_04940	5.946e-57	209.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1I16V@117743|Flavobacteriia	976|Bacteroidetes	O	Thiol peroxidase	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
TLS3_k127_5751660_1	1122931.AUAE01000016_gene2707	2.726e-97	323.0	COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,2FM8U@200643|Bacteroidia,22WI0@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
TLS3_k127_5751660_7	1408433.JHXV01000010_gene505	1.245e-30	127.0	COG0545@1|root,COG0545@2|Bacteria,4NV96@976|Bacteroidetes,1IC47@117743|Flavobacteriia,2PB8G@246874|Cryomorphaceae	976|Bacteroidetes	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
TLS3_k127_5751660_10	313606.M23134_03831	3.533e-08	64.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,47KIJ@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiB	-	5.2.1.8	ko:K01802,ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
TLS3_k127_5751660_6	794903.OPIT5_27765	2.047e-40	162.0	COG0545@1|root,COG0545@2|Bacteria,46VYS@74201|Verrucomicrobia,3K82D@414999|Opitutae	414999|Opitutae	M	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
TLS3_k127_5751660_2	158190.SpiGrapes_1927	2.286e-76	262.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,2J58N@203691|Spirochaetes	203691|Spirochaetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
TLS3_k127_5776531_1	1469557.JSWF01000016_gene2219	8.146e-80	273.0	COG1225@1|root,COG1225@2|Bacteria,4NEEA@976|Bacteroidetes,1HY6E@117743|Flavobacteriia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
TLS3_k127_5776531_2	926562.Oweho_2198	1.488e-79	269.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,1HYXC@117743|Flavobacteriia,2PAPW@246874|Cryomorphaceae	976|Bacteroidetes	H	Lumazine binding domain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
TLS3_k127_5776531_0	1124780.ANNU01000049_gene2211	8.5e-97	339.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	srrB	-	-	-	-	-	-	-	-	-	-	-	CBS,HAMP,SpoIIE,dCache_1
TLS3_k127_5776531_5	927658.AJUM01000037_gene1986	1.842e-25	109.0	2CEYK@1|root,31W5M@2|Bacteria,4NQEQ@976|Bacteroidetes,2G265@200643|Bacteroidia,3XK2K@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
TLS3_k127_5776531_3	1124780.ANNU01000049_gene2213	6.205e-67	241.0	2AAU0@1|root,33Z6J@2|Bacteria,4P4NV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5776531_4	655815.ZPR_1139	1.821e-57	204.0	COG0727@1|root,COG0727@2|Bacteria,4NJH9@976|Bacteroidetes,1HZQ3@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
TLS3_k127_5776531_6	1122225.AULQ01000009_gene313	0.0006314	45.0	2EJJC@1|root,33DAA@2|Bacteria,4NY33@976|Bacteroidetes,1I6ZT@117743|Flavobacteriia	976|Bacteroidetes	S	30S ribosomal protein Thx	-	-	-	ko:K19033	-	-	-	-	br01610,ko00000,ko03011	-	-	-	Thx
TLS3_k127_5784780_5	929562.Emtol_2649	1.615e-48	187.0	COG4783@1|root,COG4783@2|Bacteria,4NP8B@976|Bacteroidetes,47PRD@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TLS3_k127_5784780_3	1094466.KQS_11020	1.964e-79	289.0	COG1572@1|root,COG2911@1|root,COG3386@1|root,COG5492@1|root,COG1572@2|Bacteria,COG2911@2|Bacteria,COG3386@2|Bacteria,COG5492@2|Bacteria,4NJQ1@976|Bacteroidetes,1I3RW@117743|Flavobacteriia,2NUN2@237|Flavobacterium	976|Bacteroidetes	O	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHU_C
TLS3_k127_5784780_1	1392498.JQLH01000001_gene3457	1.022e-205	658.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,1HWY2@117743|Flavobacteriia,2PGWY@252356|Maribacter	976|Bacteroidetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_5784780_4	1089547.KB913013_gene4372	1.758e-60	218.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,47PCF@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
TLS3_k127_5784780_0	925409.KI911562_gene2664	8.612e-234	727.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1INXM@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
TLS3_k127_5784780_2	1453500.AT05_08550	1.406e-107	387.0	COG1572@1|root,COG2911@1|root,COG1572@2|Bacteria,COG2911@2|Bacteria,4NIU0@976|Bacteroidetes,1HXV1@117743|Flavobacteriia	976|Bacteroidetes	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5785553_1	1450525.JATV01000004_gene279	1.623e-76	268.0	COG1073@1|root,COG1073@2|Bacteria,4NSMB@976|Bacteroidetes,1IMHK@117743|Flavobacteriia,2NVM3@237|Flavobacterium	976|Bacteroidetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5785553_2	755732.Fluta_2725	1.168e-63	252.0	COG3210@1|root,COG3291@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IKDY@117743|Flavobacteriia,2PC6N@246874|Cryomorphaceae	976|Bacteroidetes	U	SPTR Conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA,SprB
TLS3_k127_5785553_5	269798.CHU_3715	2.024e-14	89.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
TLS3_k127_5785553_0	1121899.Q764_04020	0.0	1105.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,1HXSA@117743|Flavobacteriia,2NUE0@237|Flavobacterium	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
TLS3_k127_5785553_3	1380600.AUYN01000009_gene1834	4.986e-45	179.0	COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,1HXB9@117743|Flavobacteriia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
TLS3_k127_5785553_4	269798.CHU_0763	4.346e-36	143.0	28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,47M02@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5785553_6	1089547.KB913013_gene2610	0.0009181	45.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47MEM@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
TLS3_k127_580792_3	1249997.JHZW01000002_gene377	4.178e-45	176.0	COG1680@1|root,COG1680@2|Bacteria,4PI6J@976|Bacteroidetes,1IGEU@117743|Flavobacteriia,2PIUV@252356|Maribacter	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_580792_2	525257.HMPREF0204_14310	1.135e-51	201.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia,3ZQY6@59732|Chryseobacterium	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,TPR_2
TLS3_k127_580792_0	1185876.BN8_02407	1.571e-80	285.0	COG0265@1|root,COG1073@1|root,COG0265@2|Bacteria,COG1073@2|Bacteria,4P9E8@976|Bacteroidetes,47R3G@768503|Cytophagia	976|Bacteroidetes	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,PDZ_2
TLS3_k127_580792_1	926562.Oweho_2105	1.805e-53	210.0	COG3291@1|root,COG3291@2|Bacteria,4PMDA@976|Bacteroidetes,1IKH7@117743|Flavobacteriia,2PC60@246874|Cryomorphaceae	976|Bacteroidetes	E	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
TLS3_k127_581091_0	1121889.AUDM01000002_gene237	9.203e-62	231.0	COG1538@1|root,COG1538@2|Bacteria,4NEH3@976|Bacteroidetes,1HXJ9@117743|Flavobacteriia,2NT02@237|Flavobacterium	976|Bacteroidetes	MU	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_581091_1	1122226.AUHX01000005_gene2495	4.761e-48	175.0	COG0845@1|root,COG0845@2|Bacteria,4NFEK@976|Bacteroidetes,1HXDY@117743|Flavobacteriia	976|Bacteroidetes	M	Biotin attachment protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
TLS3_k127_5813222_5	1237149.C900_01621	4.096e-27	115.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,47K17@768503|Cytophagia	976|Bacteroidetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
TLS3_k127_5813222_1	468059.AUHA01000002_gene980	3.759e-202	636.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,1IPBP@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_5813222_4	927658.AJUM01000034_gene225	5.13e-34	132.0	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,2FTWG@200643|Bacteroidia,3XKCJ@558415|Marinilabiliaceae	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TLS3_k127_5813222_3	1121012.AUKX01000022_gene2456	5.86e-36	141.0	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,1I2U1@117743|Flavobacteriia,23H7G@178469|Arenibacter	976|Bacteroidetes	S	RimP C-terminal SH3 domain	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
TLS3_k127_5813222_2	1121129.KB903360_gene3054	2.639e-185	587.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,2FNJF@200643|Bacteroidia,22WBR@171551|Porphyromonadaceae	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
TLS3_k127_5813222_0	468059.AUHA01000002_gene646	4.388e-317	995.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,1IQ0V@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
TLS3_k127_5813222_6	236814.IX39_11995	9.034e-08	57.0	COG5184@1|root,COG5184@2|Bacteria,4NIP4@976|Bacteroidetes,1IIHQ@117743|Flavobacteriia,3ZNMC@59732|Chryseobacterium	976|Bacteroidetes	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,RCC1
TLS3_k127_58819_4	1094466.KQS_10725	7.516e-52	213.0	COG1357@1|root,COG3291@1|root,COG1357@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CHU_C,DUF1566,Pentapeptide
TLS3_k127_58819_0	929556.Solca_1305	1.219e-150	482.0	COG0667@1|root,COG0667@2|Bacteria,4NFCN@976|Bacteroidetes,1IQIA@117747|Sphingobacteriia	976|Bacteroidetes	C	potassium channel beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_58819_3	929556.Solca_3289	7.294e-56	199.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,1ISKV@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptide-methionine (R)-S-oxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
TLS3_k127_58819_1	1406840.Q763_12715	1.78e-124	420.0	2DBTS@1|root,2ZB0P@2|Bacteria,4NGP7@976|Bacteroidetes,1IKCE@117743|Flavobacteriia,2NY7R@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
TLS3_k127_58819_2	391598.FBBAL38_10067	3.354e-109	364.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1HXEF@117743|Flavobacteriia	976|Bacteroidetes	S	Major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
TLS3_k127_5924245_1	742766.HMPREF9455_01681	1.711e-08	55.0	COG3507@1|root,COG3507@2|Bacteria,4NEWE@976|Bacteroidetes,2FP6M@200643|Bacteroidia,22X0K@171551|Porphyromonadaceae	976|Bacteroidetes	G	Glycosyl hydrolases family 43	xynB	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
TLS3_k127_5924245_0	1237149.C900_05651	2.573e-123	408.0	COG3547@1|root,COG3547@2|Bacteria,4NGED@976|Bacteroidetes,47NI4@768503|Cytophagia	976|Bacteroidetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
TLS3_k127_5924895_0	1286632.P278_04320	2.42e-63	227.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,1HXVJ@117743|Flavobacteriia	976|Bacteroidetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
TLS3_k127_5924895_1	1121896.JMLU01000026_gene678	2.292e-36	145.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NSSE@237|Flavobacterium	976|Bacteroidetes	O	gliding motility-associated C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
TLS3_k127_5939176_3	1125971.ASJB01000030_gene1049	2.718e-49	196.0	COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria	201174|Actinobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
TLS3_k127_5939176_4	867900.Celly_0223	2.981e-18	92.0	COG5661@1|root,COG5661@2|Bacteria,4NW11@976|Bacteroidetes,1I32R@117743|Flavobacteriia,1F9G4@104264|Cellulophaga	976|Bacteroidetes	O	Bacterial protein of unknown function (DUF922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF922
TLS3_k127_5939176_1	744872.Spica_1763	9.178e-99	339.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
TLS3_k127_5939176_0	226186.BT_4011	2.73e-103	343.0	COG0338@1|root,COG0338@2|Bacteria,4NIEI@976|Bacteroidetes,2FRNF@200643|Bacteroidia,4AQN3@815|Bacteroidaceae	976|Bacteroidetes	H	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
TLS3_k127_5939176_2	525257.HMPREF0204_13192	5.629e-56	210.0	COG4251@1|root,COG4251@2|Bacteria,4NQAE@976|Bacteroidetes,1I3AG@117743|Flavobacteriia,3ZTZE@59732|Chryseobacterium	976|Bacteroidetes	T	Putative phage abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	putAbiC
TLS3_k127_6000228_0	1122176.KB903562_gene3425	1.961e-107	352.0	28I0D@1|root,2Z857@2|Bacteria,4NFD6@976|Bacteroidetes,1IRJ4@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1826
TLS3_k127_6000228_1	5888.CAK78268	1.972e-38	162.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZD5C@5878|Ciliophora	5878|Ciliophora	GOT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
TLS3_k127_6054721_6	929556.Solca_2351	0.000154	49.0	2ETRV@1|root,33M9B@2|Bacteria,4NZCJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6054721_4	925409.KI911562_gene1277	2.333e-20	96.0	COG2608@1|root,COG2608@2|Bacteria,4NUTQ@976|Bacteroidetes,1ITC9@117747|Sphingobacteriia	976|Bacteroidetes	P	Heavy-metal-associated domain	-	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA
TLS3_k127_6054721_0	1267211.KI669560_gene90	4.545e-193	626.0	COG1629@1|root,COG2608@1|root,COG2608@2|Bacteria,COG4771@2|Bacteria,4NE7A@976|Bacteroidetes,1IP85@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,HMA,Plug,TonB_dep_Rec
TLS3_k127_6054721_3	1121904.ARBP01000015_gene260	1.217e-53	201.0	COG1994@1|root,COG1994@2|Bacteria,4NRNR@976|Bacteroidetes,47UP8@768503|Cytophagia	976|Bacteroidetes	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6054721_1	1197477.IA57_08745	7.785e-91	311.0	COG1612@1|root,COG1612@2|Bacteria,4NIT1@976|Bacteroidetes,1HXU5@117743|Flavobacteriia	976|Bacteroidetes	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
TLS3_k127_6054721_2	1122226.AUHX01000005_gene2520	5.208e-75	271.0	2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,1HXZZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TLS3_k127_6054721_5	1121889.AUDM01000003_gene2413	4.443e-08	58.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NSSE@237|Flavobacterium	976|Bacteroidetes	O	gliding motility-associated C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF11,P_proprotein,fn3
TLS3_k127_6061451_1	1454007.JAUG01000003_gene3043	6.118e-80	273.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,1INTC@117747|Sphingobacteriia	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
TLS3_k127_6061451_0	1227739.Hsw_0094	4.107e-237	753.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	dpp	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
TLS3_k127_6061451_2	938709.AUSH02000045_gene372	4.814e-45	168.0	COG4319@1|root,COG4319@2|Bacteria,4NS10@976|Bacteroidetes	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
TLS3_k127_6061451_3	1434325.AZQN01000006_gene3279	1.897e-41	156.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,47KZC@768503|Cytophagia	976|Bacteroidetes	S	PFAM Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
TLS3_k127_6079430_2	929562.Emtol_2898	2.011e-72	251.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,47KTY@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
TLS3_k127_6079430_0	694427.Palpr_2125	1.896e-100	341.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes	976|Bacteroidetes	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
TLS3_k127_6079430_1	1122225.AULQ01000001_gene1769	8.008e-99	329.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,1HWQK@117743|Flavobacteriia	976|Bacteroidetes	L	TIGRFAM TIGR02757 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
TLS3_k127_6079430_5	313606.M23134_00467	4.993e-22	106.0	29N3N@1|root,3091D@2|Bacteria,4NNZB@976|Bacteroidetes,47PVZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6079430_3	385682.AFSL01000082_gene1201	1.748e-53	193.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,2FQY1@200643|Bacteroidia,3XK2G@558415|Marinilabiliaceae	976|Bacteroidetes	O	Glutathione peroxidase	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
TLS3_k127_6079430_4	929703.KE386491_gene176	1.85e-50	186.0	arCOG14808@1|root,308PC@2|Bacteria,4NR4D@976|Bacteroidetes,47PEP@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
TLS3_k127_60873_0	760192.Halhy_5071	1.571e-262	827.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IPX2@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_60873_2	679937.Bcop_0734	1.708e-159	515.0	COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,2FM6I@200643|Bacteroidia,4ANQ3@815|Bacteroidaceae	976|Bacteroidetes	J	Psort location Cytoplasmic, score	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
TLS3_k127_60873_1	1121889.AUDM01000013_gene1856	2.818e-202	640.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1HX2V@117743|Flavobacteriia,2NSUV@237|Flavobacterium	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
TLS3_k127_60873_10	1385511.N783_13120	5.568e-07	59.0	2E9CG@1|root,333K5@2|Bacteria,1V87Y@1239|Firmicutes,4HIGZ@91061|Bacilli,2YBUQ@289201|Pontibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TIMP
TLS3_k127_60873_7	926562.Oweho_1160	1.049e-45	171.0	COG0545@1|root,COG0545@2|Bacteria,4NQJS@976|Bacteroidetes,1I376@117743|Flavobacteriia,2PBTV@246874|Cryomorphaceae	976|Bacteroidetes	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
TLS3_k127_60873_8	762903.Pedsa_1475	3.868e-33	133.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
TLS3_k127_60873_4	938709.AUSH02000053_gene143	4.855e-144	466.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes	976|Bacteroidetes	E	PFAM aminotransferase class V	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
TLS3_k127_60873_6	1121930.AQXG01000004_gene2853	1.176e-47	180.0	28JIP@1|root,2Z82C@2|Bacteria,4NFN9@976|Bacteroidetes,1IQ98@117747|Sphingobacteriia	976|Bacteroidetes	S	S1 P1 nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease
TLS3_k127_60873_5	1189612.A33Q_1131	6.931e-77	266.0	COG0008@1|root,COG0008@2|Bacteria,4NP0Y@976|Bacteroidetes,47Q0Q@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
TLS3_k127_60873_3	926562.Oweho_1031	1.33e-144	485.0	COG0308@1|root,COG0308@2|Bacteria,4NGTZ@976|Bacteroidetes,1HY7M@117743|Flavobacteriia	976|Bacteroidetes	E	Aminopeptidase N	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
TLS3_k127_6091975_1	1123248.KB893345_gene28	1.335e-138	499.0	COG2706@1|root,COG3386@1|root,COG2706@2|Bacteria,COG3386@2|Bacteria,4NK33@976|Bacteroidetes,1IX26@117747|Sphingobacteriia	976|Bacteroidetes	G	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
TLS3_k127_6091975_2	1123277.KB893203_gene6265	1.323e-62	249.0	COG2373@1|root,COG3291@1|root,COG4932@1|root,COG2373@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,4NJQN@976|Bacteroidetes,47QVQ@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,IgGFc_binding,PKD,SprB,fn3
TLS3_k127_6091975_5	984262.SGRA_4206	2.357e-05	59.0	COG4935@1|root,COG4935@2|Bacteria,4P0CG@976|Bacteroidetes	976|Bacteroidetes	O	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CUB,PKD,P_proprotein
TLS3_k127_6091975_6	1408433.JHXV01000001_gene814	7.063e-05	58.0	COG3291@1|root,COG3291@2|Bacteria,4PI05@976|Bacteroidetes,1ICSF@117743|Flavobacteriia,2PBZU@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_6091975_0	929556.Solca_2328	1.231e-159	511.0	COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,1INRF@117747|Sphingobacteriia	976|Bacteroidetes	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
TLS3_k127_6091975_3	485917.Phep_0116	4.931e-61	215.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,1IRU0@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
TLS3_k127_6091975_4	1408473.JHXO01000006_gene1325	7.886e-25	105.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,2FYPS@200643|Bacteroidia	976|Bacteroidetes	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
TLS3_k127_6107977_2	388413.ALPR1_04583	8.952e-23	98.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,47JGZ@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
TLS3_k127_6107977_1	1408433.JHXV01000002_gene460	3.865e-26	117.0	28MPU@1|root,2ZAYW@2|Bacteria,4PJIE@976|Bacteroidetes,1I9N3@117743|Flavobacteriia,2PC5G@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6107977_0	1358423.N180_11380	8.832e-30	123.0	COG1765@1|root,COG1765@2|Bacteria,4NQ66@976|Bacteroidetes,1ISTX@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM OsmC-like protein	osmC	-	-	-	-	-	-	-	-	-	-	-	OsmC
TLS3_k127_6107977_3	1121373.KB903664_gene2682	1.183e-20	105.0	COG2244@1|root,COG2244@2|Bacteria,4NGVA@976|Bacteroidetes,47PAZ@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
TLS3_k127_6107977_4	880073.Calab_0118	1.699e-18	98.0	COG2911@1|root,COG4733@1|root,COG2911@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.89	ko:K01224,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DctA-YdbH,Laminin_G_3
TLS3_k127_6107977_5	1137281.D778_01193	1.741e-12	79.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
TLS3_k127_613992_4	929556.Solca_4113	8.242e-41	153.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,1INNH@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
TLS3_k127_613992_0	1408433.JHXV01000001_gene653	3.665e-136	456.0	COG2885@1|root,COG3391@1|root,COG2885@2|Bacteria,COG3391@2|Bacteria,4NFM6@976|Bacteroidetes	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_613992_2	929562.Emtol_2637	9.986e-84	286.0	COG4221@1|root,COG4221@2|Bacteria,4PKGY@976|Bacteroidetes,47JKE@768503|Cytophagia	976|Bacteroidetes	S	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_613992_1	700598.Niako_6546	2.447e-102	343.0	COG0859@1|root,COG0859@2|Bacteria,4NMIH@976|Bacteroidetes,1IW27@117747|Sphingobacteriia	976|Bacteroidetes	M	COGs COG0859 ADP-heptose LPS heptosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
TLS3_k127_613992_3	1121957.ATVL01000006_gene2838	1.402e-67	237.0	COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,47XHY@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
TLS3_k127_6150593_4	485918.Cpin_0705	2.667e-40	158.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1IQAH@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_6150593_3	1408433.JHXV01000008_gene221	3.748e-44	182.0	COG1807@1|root,COG1807@2|Bacteria,4NXNF@976|Bacteroidetes,1IMQ5@117743|Flavobacteriia,2PB6F@246874|Cryomorphaceae	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6150593_5	1313301.AUGC01000001_gene1425	3.617e-38	150.0	COG0669@1|root,COG4339@1|root,COG0669@2|Bacteria,COG4339@2|Bacteria,4NM84@976|Bacteroidetes	976|Bacteroidetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
TLS3_k127_6150593_0	929556.Solca_2463	5.988e-172	548.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1INSD@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_6150593_1	926559.JoomaDRAFT_0136	1.225e-140	452.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,1HYHD@117743|Flavobacteriia	976|Bacteroidetes	S	2-nitropropane dioxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
TLS3_k127_6150593_2	1408433.JHXV01000029_gene3118	4.407e-50	193.0	COG3637@1|root,COG3637@2|Bacteria,4NQ11@976|Bacteroidetes	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_6150593_8	762903.Pedsa_2083	9.088e-31	127.0	COG2885@1|root,COG2885@2|Bacteria,4NP5H@976|Bacteroidetes,1ITIS@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
TLS3_k127_6150593_9	762903.Pedsa_2082	2.161e-29	120.0	COG1862@1|root,COG1862@2|Bacteria,4NUT4@976|Bacteroidetes,1ITXA@117747|Sphingobacteriia	976|Bacteroidetes	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
TLS3_k127_6150593_10	468059.AUHA01000006_gene3038	1.989e-27	124.0	COG4856@1|root,COG4856@2|Bacteria,4NHJQ@976|Bacteroidetes,1IP6W@117747|Sphingobacteriia	976|Bacteroidetes	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
TLS3_k127_6150593_6	1267211.KI669560_gene1834	5.218e-37	146.0	COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,1IS7R@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
TLS3_k127_6150593_7	1124780.ANNU01000021_gene3034	2.068e-35	139.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,47KKP@768503|Cytophagia	976|Bacteroidetes	F	TIGRFAM dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
TLS3_k127_6186359_0	1229276.DI53_2252	4.264e-175	554.0	COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,1INW2@117747|Sphingobacteriia	976|Bacteroidetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
TLS3_k127_6186359_1	755732.Fluta_1926	3.293e-111	362.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia,2PBC6@246874|Cryomorphaceae	976|Bacteroidetes	C	Aldehyde dehydrogenase family	aldB	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_6217468_0	1492738.FEM21_17930	2.398e-33	139.0	2FAXV@1|root,3434Q@2|Bacteria,4P4KJ@976|Bacteroidetes,1I9RD@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6217468_1	313595.P700755_002365	1.456e-10	68.0	2CAFS@1|root,2ZMDR@2|Bacteria,4P7HR@976|Bacteroidetes,1IBIP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6276774_11	509635.N824_18420	6.471e-18	94.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,4NFTN@976|Bacteroidetes,1INM2@117747|Sphingobacteriia	976|Bacteroidetes	CE	PFAM Peptidase M1 membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
TLS3_k127_6276774_3	926551.KB900708_gene1190	4.418e-74	256.0	COG3298@1|root,COG3298@2|Bacteria,4NECH@976|Bacteroidetes,1HY85@117743|Flavobacteriia,1EQFC@1016|Capnocytophaga	976|Bacteroidetes	L	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
TLS3_k127_6276774_0	869213.JCM21142_513	1.399e-132	430.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,47K3D@768503|Cytophagia	976|Bacteroidetes	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
TLS3_k127_6276774_10	742726.HMPREF9448_02696	1.444e-21	102.0	COG0671@1|root,COG0671@2|Bacteria,4NPUG@976|Bacteroidetes,2FSUS@200643|Bacteroidia,22YR5@171551|Porphyromonadaceae	976|Bacteroidetes	I	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
TLS3_k127_6276774_5	1408433.JHXV01000019_gene1910	1.382e-59	219.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1HX0P@117743|Flavobacteriia,2PAN2@246874|Cryomorphaceae	976|Bacteroidetes	M	NAD(P)H-binding	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
TLS3_k127_6276774_2	755732.Fluta_1042	3.84e-103	338.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,1HXE9@117743|Flavobacteriia,2PA5G@246874|Cryomorphaceae	976|Bacteroidetes	F	Deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
TLS3_k127_6276774_9	1408433.JHXV01000010_gene535	9.668e-27	116.0	2AAU0@1|root,30Y70@2|Bacteria,4PBYC@976|Bacteroidetes,1ICQX@117743|Flavobacteriia,2PBTU@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6276774_7	1408433.JHXV01000012_gene3884	2.182e-42	171.0	COG0438@1|root,COG0438@2|Bacteria,4PI54@976|Bacteroidetes,1I2FR@117743|Flavobacteriia,2PB22@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_6276774_8	491205.JARQ01000005_gene1705	4.985e-34	145.0	COG2244@1|root,COG2244@2|Bacteria,4NRKF@976|Bacteroidetes,1I3V4@117743|Flavobacteriia,3ZR5J@59732|Chryseobacterium	976|Bacteroidetes	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
TLS3_k127_6276774_4	1341155.FSS13T_15000	1.327e-67	238.0	COG1566@1|root,COG1566@2|Bacteria,4PM4J@976|Bacteroidetes,1IJJ9@117743|Flavobacteriia,2NWIY@237|Flavobacterium	976|Bacteroidetes	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
TLS3_k127_6276774_6	1122918.KB907256_gene2237	3.665e-51	185.0	COG3832@1|root,COG3832@2|Bacteria,1V799@1239|Firmicutes,4HHAD@91061|Bacilli,26WTI@186822|Paenibacillaceae	91061|Bacilli	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_6276774_1	1239962.C943_02087	8.632e-109	358.0	COG3832@1|root,COG3865@1|root,COG3832@2|Bacteria,COG3865@2|Bacteria,4NE70@976|Bacteroidetes,47PVI@768503|Cytophagia	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
TLS3_k127_6297821_1	1041826.FCOL_06745	8.431e-56	203.0	COG1266@1|root,COG1266@2|Bacteria,4NFKV@976|Bacteroidetes,1HY21@117743|Flavobacteriia,2NTMD@237|Flavobacterium	976|Bacteroidetes	S	Abortive phage infection protein	yyaK	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
TLS3_k127_6297821_0	929562.Emtol_3085	1.3e-145	477.0	COG3975@1|root,COG3975@2|Bacteria,4NE4D@976|Bacteroidetes,47NWB@768503|Cytophagia	976|Bacteroidetes	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
TLS3_k127_6302419_0	1121899.Q764_01610	0.0	1477.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,1HYI9@117743|Flavobacteriia,2NSQU@237|Flavobacterium	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
TLS3_k127_6310559_6	1403819.BATR01000096_gene3091	4.583e-35	140.0	COG1680@1|root,COG1680@2|Bacteria,46VJ9@74201|Verrucomicrobia,2IUVM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3887
TLS3_k127_6310559_8	1517682.HW49_05310	1.077e-33	142.0	2D45Q@1|root,32TGB@2|Bacteria,4NTFZ@976|Bacteroidetes,2FU27@200643|Bacteroidia,230P4@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6310559_7	1148.1651934	6.093e-34	134.0	COG3542@1|root,COG3542@2|Bacteria,1G6JR@1117|Cyanobacteria,1H65M@1142|Synechocystis	1117|Cyanobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
TLS3_k127_6310559_0	926562.Oweho_3020	1.805e-135	442.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,1HX4E@117743|Flavobacteriia,2PA4E@246874|Cryomorphaceae	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS3_k127_6310559_2	1250006.JHZZ01000001_gene587	8.594e-73	250.0	COG0500@1|root,COG0500@2|Bacteria,4NNNE@976|Bacteroidetes,1I1JP@117743|Flavobacteriia,3VVVP@52959|Polaribacter	976|Bacteroidetes	Q	Thiopurine S-methyltransferase (TPMT)	tpm	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
TLS3_k127_6310559_1	1121957.ATVL01000006_gene3097	8.705e-122	404.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,47MW2@768503|Cytophagia	976|Bacteroidetes	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
TLS3_k127_6310559_5	1408433.JHXV01000010_gene528	2.832e-37	143.0	COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,1I1YF@117743|Flavobacteriia,2PB2E@246874|Cryomorphaceae	976|Bacteroidetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
TLS3_k127_6310559_14	755732.Fluta_4050	1.933e-06	52.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
TLS3_k127_6310559_9	1086011.HJ01_03476	1.222e-26	113.0	2EBJZ@1|root,335KD@2|Bacteria,4NWP2@976|Bacteroidetes,1IBI0@117743|Flavobacteriia,2NWNQ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6310559_10	694427.Palpr_2673	4.649e-23	103.0	2EC34@1|root,33623@2|Bacteria,4NVW7@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
TLS3_k127_6310559_11	1123248.KB893348_gene130	2.947e-17	84.0	COG4980@1|root,COG4980@2|Bacteria,4NXB3@976|Bacteroidetes,1ITYD@117747|Sphingobacteriia	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
TLS3_k127_6310559_12	927658.AJUM01000037_gene1869	3.748e-15	76.0	2EFZF@1|root,339RM@2|Bacteria,4NXMV@976|Bacteroidetes,2FZWY@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
TLS3_k127_6310559_4	1270193.JARP01000004_gene1418	7.52e-64	224.0	COG3685@1|root,COG3685@2|Bacteria,4NMCT@976|Bacteroidetes,1I1BM@117743|Flavobacteriia,2NUHM@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
TLS3_k127_6310559_3	269798.CHU_2068	1.523e-67	234.0	COG4572@1|root,COG4572@2|Bacteria,4PM1W@976|Bacteroidetes,47XZW@768503|Cytophagia	976|Bacteroidetes	S	Cation transport regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6310559_13	714943.Mucpa_6954	5.757e-09	63.0	2EH83@1|root,33AZY@2|Bacteria,4NXRB@976|Bacteroidetes,1IZSD@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6315101_6	1341155.FSS13T_12140	3.589e-32	141.0	COG2247@1|root,COG3391@1|root,COG2247@2|Bacteria,COG3391@2|Bacteria,4NPTS@976|Bacteroidetes,1I3F0@117743|Flavobacteriia	976|Bacteroidetes	M	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
TLS3_k127_6315101_10	321332.CYB_2367	3.518e-18	100.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.91	ko:K07004,ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_2,CHU_C,FlgD_ig,Glyco_hydro_6,Laminin_G_3,PKD,VCBS
TLS3_k127_6315101_0	1313421.JHBV01000028_gene1857	7.642e-221	720.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
TLS3_k127_6315101_15	236814.IX39_03840	3.587e-06	61.0	COG5520@1|root,COG5520@2|Bacteria,4NKP9@976|Bacteroidetes,1I3C8@117743|Flavobacteriia,3ZR0Y@59732|Chryseobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	xynC_2	-	3.2.1.136	ko:K15924	-	-	-	-	ko00000,ko01000	-	GH5	-	Glyco_hydro_30,Glyco_hydro_30C,Glyco_hydro_cc
TLS3_k127_6315101_13	1122179.KB890466_gene624	1.8e-10	76.0	COG3209@1|root,COG3291@1|root,COG4932@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,PKD,SprB
TLS3_k127_6315101_1	1313421.JHBV01000028_gene1857	1.317e-164	567.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
TLS3_k127_6315101_3	1123508.JH636453_gene5802	9.92e-114	403.0	COG3210@1|root,COG3391@1|root,COG3827@1|root,COG4932@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,COG3827@2|Bacteria,COG4932@2|Bacteria,2IY8U@203682|Planctomycetes	203682|Planctomycetes	M	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS3_k127_6315101_5	386456.JQKN01000001_gene2316	1.049e-34	153.0	arCOG02349@1|root,arCOG06721@1|root,arCOG02349@2157|Archaea,arCOG06721@2157|Archaea,2Y2Z1@28890|Euryarchaeota	28890|Euryarchaeota	T	HWE histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2
TLS3_k127_6315101_4	504487.JCM19302_2218	4.99e-45	172.0	COG3279@1|root,COG3279@2|Bacteria,4NKXC@976|Bacteroidetes,1I0BK@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_6315101_12	760192.Halhy_4071	6.335e-12	66.0	COG3668@1|root,COG3668@2|Bacteria,4NYCZ@976|Bacteroidetes	976|Bacteroidetes	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
TLS3_k127_6315101_14	491205.JARQ01000007_gene3170	3.426e-06	52.0	2C5NC@1|root,3392V@2|Bacteria,4PC5B@976|Bacteroidetes,1IGTP@117743|Flavobacteriia,3ZSVT@59732|Chryseobacterium	491205.JARQ01000007_gene3170|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6315101_9	525373.HMPREF0766_11289	2.168e-20	105.0	COG5295@1|root,COG5295@2|Bacteria,4NR0E@976|Bacteroidetes	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6315101_7	760192.Halhy_5276	2.256e-27	130.0	COG3934@1|root,COG3934@2|Bacteria,4NJJS@976|Bacteroidetes	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,DUF5060
TLS3_k127_6315101_16	1094466.KQS_04320	0.0001415	55.0	COG2358@1|root,COG3209@1|root,COG2358@2|Bacteria,COG3209@2|Bacteria,4PPGI@976|Bacteroidetes,1IKM6@117743|Flavobacteriia,2NX0I@237|Flavobacterium	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6315101_11	1443665.JACA01000001_gene2944	2.059e-17	84.0	COG1476@1|root,COG1476@2|Bacteria,4PPVF@976|Bacteroidetes,1IKV2@117743|Flavobacteriia,2YK5A@290174|Aquimarina	976|Bacteroidetes	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6315101_2	1042209.HK44_019395	2.696e-119	391.0	28JBZ@1|root,2Z96M@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1837
TLS3_k127_6315101_8	1250278.JQNQ01000001_gene1336	6.341e-27	111.0	COG1204@1|root,COG1204@2|Bacteria,4NKRN@976|Bacteroidetes,1HZSY@117743|Flavobacteriia	976|Bacteroidetes	L	DEAD/DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
TLS3_k127_6316160_9	1313421.JHBV01000010_gene4140	1.382e-25	125.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Hint_2,PKD,SprB
TLS3_k127_6316160_6	700598.Niako_3929	3.812e-78	295.0	COG3291@1|root,COG3291@2|Bacteria,4NJQN@976|Bacteroidetes,1IXWG@117747|Sphingobacteriia	976|Bacteroidetes	M	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,IgGFc_binding,PKD,SprB,fn3
TLS3_k127_6316160_5	1189619.pgond44_04780	1.163e-80	274.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,1HXFE@117743|Flavobacteriia,4C34Y@83612|Psychroflexus	976|Bacteroidetes	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
TLS3_k127_6316160_10	1313421.JHBV01000037_gene2890	9.663e-23	109.0	2FG80@1|root,3484C@2|Bacteria,4P5E2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6316160_3	926562.Oweho_0903	9.434e-143	467.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,4NFIA@976|Bacteroidetes,1HXE1@117743|Flavobacteriia,2PAGQ@246874|Cryomorphaceae	976|Bacteroidetes	M	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
TLS3_k127_6316160_4	929556.Solca_0551	7.85e-100	332.0	COG0382@1|root,COG0382@2|Bacteria,4NEE3@976|Bacteroidetes,1IP3B@117747|Sphingobacteriia	976|Bacteroidetes	H	4-hydroxybenzoate polyprenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
TLS3_k127_6316160_12	485917.Phep_1813	5.507e-11	66.0	290EP@1|root,2ZXKF@2|Bacteria,4P7RC@976|Bacteroidetes,1IZYH@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6316160_11	485917.Phep_1814	6.893e-19	89.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
TLS3_k127_6316160_7	269798.CHU_1878	3.879e-48	183.0	28IS5@1|root,2Z8RB@2|Bacteria,4NIIH@976|Bacteroidetes,47R7X@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6316160_8	714943.Mucpa_2741	3.712e-40	153.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,1ISTA@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family UPF0079, ATPase	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
TLS3_k127_6316160_1	929556.Solca_4088	4.697e-210	664.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,1IP34@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
TLS3_k127_6316160_2	468059.AUHA01000002_gene691	7.317e-162	519.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1IQIS@117747|Sphingobacteriia	976|Bacteroidetes	S	phosphohydrolase	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
TLS3_k127_6316160_0	1191523.MROS_1275	4.299e-269	844.0	COG0457@1|root,COG0457@2|Bacteria	1191523.MROS_1275|-	S	peptidyl-tyrosine sulfation	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
TLS3_k127_6342835_9	269798.CHU_3639	3.698e-05	55.0	2C2MT@1|root,347EH@2|Bacteria,4P6C0@976|Bacteroidetes,47VTR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6342835_2	1270196.JCKI01000002_gene327	7.691e-44	164.0	COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes	976|Bacteroidetes	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
TLS3_k127_6342835_5	1121899.Q764_01120	1.009e-38	146.0	COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,1I2TD@117743|Flavobacteriia,2NWT1@237|Flavobacterium	976|Bacteroidetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
TLS3_k127_6342835_4	269798.CHU_2591	8.786e-40	151.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,47QQD@768503|Cytophagia	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
TLS3_k127_6342835_3	216432.CA2559_00625	3.249e-40	161.0	COG3342@1|root,COG3342@2|Bacteria	2|Bacteria	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,MAM,Peptidase_M14,fn3
TLS3_k127_6342835_0	153721.MYP_2228	7.11e-293	933.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
TLS3_k127_6342835_6	1408473.JHXO01000010_gene3653	1.914e-37	153.0	COG5653@1|root,COG5653@2|Bacteria,4NQN5@976|Bacteroidetes,2FT4P@200643|Bacteroidia	976|Bacteroidetes	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
TLS3_k127_6342835_1	326298.Suden_1419	1.066e-95	325.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42UBA@68525|delta/epsilon subdivisions,2YQIM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
TLS3_k127_6342835_7	1034943.BN1094_00510	4.063e-25	114.0	COG1215@1|root,COG1215@2|Bacteria,1QVTJ@1224|Proteobacteria,1T5HP@1236|Gammaproteobacteria,1JF2C@118969|Legionellales	118969|Legionellales	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_6366478_1	485917.Phep_1328	7.196e-98	329.0	COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,1IV3Y@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	fecA	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_6366478_3	1123035.ARLA01000027_gene402	6.367e-63	233.0	COG5164@1|root,COG5295@1|root,COG5164@2|Bacteria,COG5295@2|Bacteria,4PHV9@976|Bacteroidetes,1IEJ9@117743|Flavobacteriia,4C4EI@83612|Psychroflexus	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	-
TLS3_k127_6366478_0	1380600.AUYN01000001_gene2318	5.545e-302	949.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1HWUW@117743|Flavobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
TLS3_k127_6366478_7	546264.NEIFLAOT_02312	8.274e-28	114.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,2KS03@206351|Neisseriales	206351|Neisseriales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
TLS3_k127_6366478_5	1227739.Hsw_1186	1.401e-44	171.0	2DBUB@1|root,2ZB53@2|Bacteria,4NMWS@976|Bacteroidetes,47P3Z@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6366478_6	1408473.JHXO01000006_gene1206	1.619e-37	158.0	COG0526@1|root,COG0526@2|Bacteria,4NNSW@976|Bacteroidetes,2FXHS@200643|Bacteroidia	976|Bacteroidetes	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_8
TLS3_k127_6366478_2	1123234.AUKI01000011_gene1056	1.841e-84	286.0	COG0564@1|root,COG0564@2|Bacteria,4NFS8@976|Bacteroidetes,1HXBY@117743|Flavobacteriia	976|Bacteroidetes	J	Pseudouridine synthase	rluC	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
TLS3_k127_6366478_4	1034807.FBFL15_1180	4.96e-61	217.0	COG0010@1|root,COG0010@2|Bacteria,4NEFA@976|Bacteroidetes,1HX39@117743|Flavobacteriia,2NSHA@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the arginase family	hutG	-	3.5.3.7,3.5.3.8	ko:K01479,ko:K12255	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045	R01990,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS3_k127_6383386_7	1237149.C900_00750	4.574e-30	123.0	COG1752@1|root,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,47QDC@768503|Cytophagia	976|Bacteroidetes	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
TLS3_k127_6383386_3	929562.Emtol_2753	1.286e-83	284.0	COG0730@1|root,COG0730@2|Bacteria,4NFTT@976|Bacteroidetes,47RU3@768503|Cytophagia	976|Bacteroidetes	S	PFAM Sulfite exporter TauE SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_6383386_4	411154.GFO_0525	5.165e-55	198.0	299YT@1|root,2ZX0H@2|Bacteria,4NP1B@976|Bacteroidetes,1I3KF@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
TLS3_k127_6383386_0	1454007.JAUG01000001_gene3682	1.459e-198	644.0	COG0507@1|root,COG0507@2|Bacteria,4NF6J@976|Bacteroidetes,1IQC3@117747|Sphingobacteriia	976|Bacteroidetes	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	HTH_40,Herpes_Helicase,PIF1,UvrD_C_2
TLS3_k127_6383386_8	313595.P700755_000294	1.407e-17	83.0	COG1943@1|root,COG1943@2|Bacteria,4NPWC@976|Bacteroidetes,1I28P@117743|Flavobacteriia,4C4FE@83612|Psychroflexus	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
TLS3_k127_6383386_6	1121904.ARBP01000010_gene2423	1.828e-32	130.0	COG3832@1|root,COG3832@2|Bacteria,4NT4P@976|Bacteroidetes,47R8X@768503|Cytophagia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_6383386_1	929556.Solca_1732	1.707e-126	415.0	COG1533@1|root,COG1533@2|Bacteria,4NE62@976|Bacteroidetes,1IPD6@117747|Sphingobacteriia	976|Bacteroidetes	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TLS3_k127_6383386_2	1408473.JHXO01000007_gene788	1.247e-122	408.0	COG2176@1|root,COG2176@2|Bacteria,4PM8C@976|Bacteroidetes,2FW8F@200643|Bacteroidia	976|Bacteroidetes	L	GIY-YIG type nucleases (URI domain)	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
TLS3_k127_6383386_9	886377.Murru_1234	1.162e-13	72.0	COG2827@1|root,COG2827@2|Bacteria,4NSI7@976|Bacteroidetes,1I49F@117743|Flavobacteriia	976|Bacteroidetes	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
TLS3_k127_6415462_1	761193.Runsl_3570	7.663e-186	587.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes,47MSW@768503|Cytophagia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_6415462_3	926549.KI421517_gene1036	9.798e-13	74.0	2DZN5@1|root,33CRM@2|Bacteria,4NZFZ@976|Bacteroidetes,47T7Y@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6415462_4	485918.Cpin_3000	1.858e-06	51.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IT98@117747|Sphingobacteriia	976|Bacteroidetes	L	resolvase domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
TLS3_k127_6415462_2	1308866.J416_13089	2.608e-55	201.0	COG2105@1|root,COG2105@2|Bacteria,1V154@1239|Firmicutes,4HEQE@91061|Bacilli,471EV@74385|Gracilibacillus	91061|Bacilli	S	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6415462_0	1250278.JQNQ01000001_gene1336	4.582e-243	763.0	COG1204@1|root,COG1204@2|Bacteria,4NKRN@976|Bacteroidetes,1HZSY@117743|Flavobacteriia	976|Bacteroidetes	L	DEAD/DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
TLS3_k127_643459_4	1223410.KN050846_gene2474	0.000539	43.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI1V@976|Bacteroidetes,1HWSH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
TLS3_k127_643459_1	1121897.AUGO01000012_gene2837	6.714e-45	170.0	COG2197@1|root,COG2197@2|Bacteria,4PI93@976|Bacteroidetes,1IG32@117743|Flavobacteriia,2NV3E@237|Flavobacterium	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_643459_2	525257.HMPREF0204_13533	7.869e-36	141.0	COG2318@1|root,COG2318@2|Bacteria,4NSE5@976|Bacteroidetes,1I4NU@117743|Flavobacteriia,3ZRNS@59732|Chryseobacterium	976|Bacteroidetes	S	Damage-inducible protein DinB	-	-	-	-	-	-	-	-	-	-	-	-	DinB
TLS3_k127_643459_0	1121481.AUAS01000011_gene4981	3.003e-277	873.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia	976|Bacteroidetes	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
TLS3_k127_643459_3	573370.DMR_21190	8.921e-20	102.0	COG4262@1|root,COG4262@2|Bacteria,1PC06@1224|Proteobacteria,42U5M@68525|delta/epsilon subdivisions,2WQRR@28221|Deltaproteobacteria,2MGK6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
TLS3_k127_647365_1	869213.JCM21142_31278	3.552e-29	119.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NHSC@976|Bacteroidetes,47XEJ@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Reg_prop,SpoIIE,Y_Y_Y
TLS3_k127_647365_2	1123037.AUDE01000032_gene2254	1.815e-12	71.0	COG3071@1|root,COG3071@2|Bacteria,4NUU1@976|Bacteroidetes	976|Bacteroidetes	H	HemY protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_17,TPR_8
TLS3_k127_647365_0	1168034.FH5T_08175	1.269e-150	482.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,2FNZN@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
TLS3_k127_6529846_3	756272.Plabr_1132	1.832e-14	82.0	2B79J@1|root,320CA@2|Bacteria,2J24W@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1643)	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6529846_1	1238450.VIBNISOn1_1590001	1.1e-38	159.0	COG3886@1|root,COG3886@2|Bacteria,1RBQT@1224|Proteobacteria	1224|Proteobacteria	L	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
TLS3_k127_6529846_0	720554.Clocl_1698	0.0	1347.0	COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,248A6@186801|Clostridia,3WGWH@541000|Ruminococcaceae	186801|Clostridia	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
TLS3_k127_6529846_2	1036674.A28LD_0625	4.335e-22	105.0	arCOG14672@1|root,33PIQ@2|Bacteria,1NSVD@1224|Proteobacteria,1SMHB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6551512_0	468059.AUHA01000002_gene279	5.915e-151	486.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1IPP6@117747|Sphingobacteriia	976|Bacteroidetes	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_6551512_1	1229276.DI53_0407	6.915e-95	316.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1IQ8P@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
TLS3_k127_6551512_2	313606.M23134_08259	7.974e-50	190.0	COG0860@1|root,COG0860@2|Bacteria,4P3RX@976|Bacteroidetes,47V02@768503|Cytophagia	976|Bacteroidetes	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
TLS3_k127_6551602_5	1408813.AYMG01000034_gene4476	9.31e-46	176.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1IQEU@117747|Sphingobacteriia	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	fjo14	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
TLS3_k127_6551602_8	504487.JCM19302_3319	3.539e-27	113.0	COG1359@1|root,COG1359@2|Bacteria,4NSV0@976|Bacteroidetes,1I40Y@117743|Flavobacteriia	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
TLS3_k127_6551602_4	649349.Lbys_0596	2.114e-55	200.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,47KTP@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
TLS3_k127_6551602_2	945713.IALB_2776	1.151e-85	291.0	COG0682@1|root,COG0682@2|Bacteria	2|Bacteria	M	lipoprotein biosynthetic process	lgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.1.1.199	ko:K03438,ko:K13292	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	LGT
TLS3_k127_6551602_0	926551.KB900704_gene646	5.221e-203	638.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,1HWP1@117743|Flavobacteriia,1EQ9H@1016|Capnocytophaga	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
TLS3_k127_6551602_3	1408473.JHXO01000006_gene1182	9.146e-71	246.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,2FM71@200643|Bacteroidia	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
TLS3_k127_6551602_1	755732.Fluta_0965	1.775e-143	458.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1HWTI@117743|Flavobacteriia,2PA62@246874|Cryomorphaceae	976|Bacteroidetes	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
TLS3_k127_6551602_7	1121957.ATVL01000008_gene4254	4.141e-33	145.0	COG3209@1|root,COG3209@2|Bacteria,4PHTT@976|Bacteroidetes,47WSE@768503|Cytophagia	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6551602_9	269798.CHU_0305	1.203e-13	76.0	2EQRC@1|root,33IB7@2|Bacteria,4NZAZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6551602_6	316067.Geob_1283	1.636e-36	153.0	COG1361@1|root,COG1404@1|root,COG3210@1|root,COG4625@1|root,COG4886@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG4886@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Cadherin_3,DUF11,DUF4347,He_PIG,PATR
TLS3_k127_6555757_8	491916.RHECIAT_CH0000838	1.28e-18	93.0	COG1861@1|root,COG1861@2|Bacteria,1RG42@1224|Proteobacteria,2UABZ@28211|Alphaproteobacteria,4BEAT@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Cytidylyltransferase	-	-	-	ko:K07257	-	-	-	-	ko00000	-	-	-	CTP_transf_3
TLS3_k127_6555757_6	1313421.JHBV01000004_gene705	9.813e-34	143.0	COG2089@1|root,COG2089@2|Bacteria,4NEKD@976|Bacteroidetes,1IRJN@117747|Sphingobacteriia	976|Bacteroidetes	M	synthase	neuB	-	2.5.1.101,2.5.1.132,2.5.1.56	ko:K01654,ko:K18430,ko:K21279	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
TLS3_k127_6555757_2	1317122.ATO12_22790	4.452e-65	232.0	COG0667@1|root,COG0667@2|Bacteria,4NS3R@976|Bacteroidetes,1I4E5@117743|Flavobacteriia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_6555757_0	880071.Fleli_3540	2.798e-174	553.0	COG0399@1|root,COG0399@2|Bacteria,4NFQ8@976|Bacteroidetes,47K8X@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_6555757_3	1117319.PSPO_07604	1.796e-56	204.0	COG0500@1|root,COG0500@2|Bacteria,1NME2@1224|Proteobacteria,1SIWG@1236|Gammaproteobacteria,2Q4RN@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_6555757_1	1121899.Q764_03440	1.031e-167	532.0	COG1086@1|root,COG1086@2|Bacteria,4NGN2@976|Bacteroidetes,1HYI6@117743|Flavobacteriia,2NVDV@237|Flavobacterium	976|Bacteroidetes	M	Male sterility protein	pseB	-	4.2.1.115,5.1.3.2	ko:K15894,ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00362	R00291,R09697	RC00289,RC02609	ko00000,ko00001,ko00002,ko01000	-	-	-	Polysacc_syn_2C,Polysacc_synt_2
TLS3_k127_6555757_7	421072.IO89_13725	9.711e-22	100.0	COG0615@1|root,COG0615@2|Bacteria,4NM74@976|Bacteroidetes,1I1PT@117743|Flavobacteriia,3HI32@358033|Chryseobacterium	976|Bacteroidetes	IM	Cytidylyltransferase-like	-	-	2.7.7.39	ko:K00980	ko00564,map00564	-	R00856	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
TLS3_k127_6555757_4	1268239.PALB_5970	6.473e-49	186.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,2Q1TP@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG0451 Nucleoside-diphosphate-sugar epimerases	wbnF	-	5.1.3.25,5.1.3.6,5.1.3.7	ko:K02473,ko:K08679,ko:K17947	ko00520,ko00523,ko01100,ko01130,map00520,map00523,map01100,map01130	-	R00418,R01385,R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
TLS3_k127_6555757_5	1280664.AUIX01000015_gene2203	3.524e-34	135.0	COG0279@1|root,COG0279@2|Bacteria,1V4TB@1239|Firmicutes,24JYA@186801|Clostridia,4C22V@830|Butyrivibrio	186801|Clostridia	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
TLS3_k127_6591307_0	1408433.JHXV01000029_gene3104	7.95e-144	485.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia,2PA6D@246874|Cryomorphaceae	976|Bacteroidetes	DM	Chain length determinant protein	wzc	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
TLS3_k127_6595423_8	1121904.ARBP01000069_gene5063	6.067e-64	227.0	COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,47KFP@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor	fecA	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_6595423_2	1237149.C900_02515	1.134e-136	448.0	COG3250@1|root,COG3250@2|Bacteria,4NE9C@976|Bacteroidetes,47KZT@768503|Cytophagia	976|Bacteroidetes	G	Horizontally Transferred TransMembrane Domain	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
TLS3_k127_6595423_7	1237149.C900_02514	5.287e-64	233.0	COG3489@1|root,COG3489@2|Bacteria,4NFAT@976|Bacteroidetes,47NBA@768503|Cytophagia	976|Bacteroidetes	S	Imelysin	-	-	-	ko:K07338	-	-	-	-	ko00000	-	-	-	Peptidase_M75
TLS3_k127_6595423_4	643867.Ftrac_2418	2.261e-99	336.0	28HNS@1|root,2Z7WY@2|Bacteria,4NDYC@976|Bacteroidetes,47RCV@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4856)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4856
TLS3_k127_6595423_0	485918.Cpin_4040	1.543e-199	635.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1IQZU@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase M1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
TLS3_k127_6595423_1	485917.Phep_4117	2.811e-143	463.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,1IW3S@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TLS3_k127_6595423_3	926556.Echvi_1206	9.059e-107	350.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,47M0E@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
TLS3_k127_6595423_5	485918.Cpin_2595	1.678e-76	265.0	COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,1IRHE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Bacterial lipid A biosynthesis acyltransferase	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
TLS3_k127_6595423_6	929703.KE386491_gene371	4.14e-72	261.0	COG4485@1|root,COG4485@2|Bacteria,4NUQF@976|Bacteroidetes	976|Bacteroidetes	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
TLS3_k127_659751_2	755732.Fluta_1246	1.044e-12	76.0	COG0260@1|root,COG0260@2|Bacteria,4NDWT@976|Bacteroidetes,1HZZ2@117743|Flavobacteriia,2PA9B@246874|Cryomorphaceae	976|Bacteroidetes	E	Cytosol aminopeptidase family, catalytic domain	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
TLS3_k127_659751_1	926562.Oweho_3551	9.413e-24	104.0	COG0239@1|root,COG0239@2|Bacteria,4P9SD@976|Bacteroidetes,1IEE9@117743|Flavobacteriia,2PBA2@246874|Cryomorphaceae	976|Bacteroidetes	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
TLS3_k127_659751_0	1144313.PMI10_02824	6.411e-74	255.0	COG1738@1|root,COG1738@2|Bacteria,4NNPU@976|Bacteroidetes,1I2GG@117743|Flavobacteriia,2NU67@237|Flavobacterium	976|Bacteroidetes	U	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
TLS3_k127_6603901_6	926562.Oweho_1341	8.925e-41	158.0	COG2304@1|root,COG2304@2|Bacteria,4NJF1@976|Bacteroidetes,1I5HE@117743|Flavobacteriia,2PAI7@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
TLS3_k127_6603901_0	761193.Runsl_2487	0.0	1240.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47NMF@768503|Cytophagia	976|Bacteroidetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
TLS3_k127_6603901_4	761193.Runsl_1454	9.61e-68	237.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,47JSQ@768503|Cytophagia	976|Bacteroidetes	K	Iron dependent repressor, metal binding and dimerisation domain	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
TLS3_k127_6603901_1	1506583.JQJY01000006_gene4398	9.878e-229	723.0	COG0589@1|root,COG1914@1|root,COG0589@2|Bacteria,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,1HXXF@117743|Flavobacteriia,2NTC3@237|Flavobacterium	976|Bacteroidetes	PT	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp,Usp
TLS3_k127_6603901_2	1235803.C825_03903	1.088e-90	312.0	COG0438@1|root,COG0438@2|Bacteria,4NFMB@976|Bacteroidetes,2FMJE@200643|Bacteroidia,22XBH@171551|Porphyromonadaceae	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
TLS3_k127_6603901_3	153721.MYP_4106	1.525e-79	277.0	COG3391@1|root,COG3391@2|Bacteria,4NESV@976|Bacteroidetes,47MV5@768503|Cytophagia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2
TLS3_k127_6603901_5	269798.CHU_1608	6.874e-42	167.0	COG3291@1|root,COG3291@2|Bacteria,4NJ39@976|Bacteroidetes,47SJS@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4465)	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Beta_helix,DUF4465
TLS3_k127_6604068_0	929556.Solca_3389	6.627e-113	376.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1INME@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_6604068_1	929556.Solca_1745	3.672e-107	352.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,1IP6T@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0488 ATPase components of ABC transporter with duplicated ATPase domains	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_6623888_0	1121373.KB903632_gene397	6.239e-121	402.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,47MPC@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0659 Sulfate permease and related transporter (MFS superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Sulfate_transp
TLS3_k127_6623888_1	926562.Oweho_1696	8.624e-119	397.0	2BVKK@1|root,2Z8PC@2|Bacteria,4NF9X@976|Bacteroidetes,1I06A@117743|Flavobacteriia,2PAVD@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
TLS3_k127_6623888_3	215803.DB30_5113	3.265e-69	253.0	COG0793@1|root,COG0793@2|Bacteria,1RGID@1224|Proteobacteria,4382G@68525|delta/epsilon subdivisions,2X3CI@28221|Deltaproteobacteria,2YVET@29|Myxococcales	28221|Deltaproteobacteria	M	tail specific protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
TLS3_k127_6623888_2	1380384.JADN01000003_gene620	1.893e-77	267.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,1HX9E@117743|Flavobacteriia	976|Bacteroidetes	M	Hydrolase Nlp P60	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
TLS3_k127_6623888_4	929556.Solca_2449	9.201e-56	198.0	COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,1IRT0@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
TLS3_k127_6623888_5	1231241.Mc24_04465	9.802e-09	61.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
TLS3_k127_6623888_6	742726.HMPREF9448_00842	1.903e-06	55.0	COG3291@1|root,COG3291@2|Bacteria,4NKVV@976|Bacteroidetes,2FM9I@200643|Bacteroidia	976|Bacteroidetes	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
TLS3_k127_6642307_4	1288963.ADIS_3702	3.233e-67	251.0	COG0845@1|root,COG0845@2|Bacteria,4NFEK@976|Bacteroidetes,47JV7@768503|Cytophagia	976|Bacteroidetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
TLS3_k127_6642307_8	1131812.JQMS01000001_gene1477	2.644e-41	172.0	COG2274@1|root,COG2274@2|Bacteria,4NFJF@976|Bacteroidetes,1HWYH@117743|Flavobacteriia,2NSS2@237|Flavobacterium	976|Bacteroidetes	V	ABC transporter ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
TLS3_k127_6642307_3	686340.Metal_0288	1.031e-72	252.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_6642307_1	1168034.FH5T_04380	3.751e-135	441.0	COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,2FW97@200643|Bacteroidia	976|Bacteroidetes	E	Alanine dehydrogenase/PNT, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
TLS3_k127_6642307_7	761193.Runsl_3693	1.245e-52	205.0	COG0793@1|root,COG0793@2|Bacteria,4NGGJ@976|Bacteroidetes,47PB5@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
TLS3_k127_6642307_0	755732.Fluta_2949	1.908e-146	475.0	COG0582@1|root,COG0582@2|Bacteria,4NDZJ@976|Bacteroidetes,1IJ6S@117743|Flavobacteriia,2PC1M@246874|Cryomorphaceae	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase
TLS3_k127_6642307_11	365044.Pnap_2888	1.322e-14	83.0	COG1309@1|root,COG1309@2|Bacteria,1N659@1224|Proteobacteria,2VS47@28216|Betaproteobacteria,4AE9P@80864|Comamonadaceae	28216|Betaproteobacteria	K	Tetracycline transcriptional repressor MAATS-type	acrR	-	-	ko:K03577	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C_2,TetR_N
TLS3_k127_6642307_5	402612.FP1574	6.121e-65	242.0	2E8Z7@1|root,3338T@2|Bacteria,4NWZT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6642307_9	755732.Fluta_3001	1.558e-28	118.0	2E3D7@1|root,32YCE@2|Bacteria,4NVGT@976|Bacteroidetes,1I3YB@117743|Flavobacteriia	976|Bacteroidetes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
TLS3_k127_6642307_6	866536.Belba_1260	2.58e-60	220.0	28HND@1|root,2Z7WP@2|Bacteria,4NMSD@976|Bacteroidetes,47R3R@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6642307_2	1453498.LG45_16190	1.364e-77	265.0	COG1484@1|root,COG1484@2|Bacteria,4NFYG@976|Bacteroidetes,1HYFC@117743|Flavobacteriia,2P0PJ@237|Flavobacterium	976|Bacteroidetes	L	DNA-dependent DNA replication	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6642307_10	118173.KB235914_gene2216	1.99e-24	122.0	COG2351@1|root,COG2885@1|root,COG2351@2|Bacteria,COG2885@2|Bacteria,1G4CU@1117|Cyanobacteria,1H7ZW@1150|Oscillatoriales	2|Bacteria	M	Salmonella virulence plasmid 28.1kDa A protein	uraH	GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009112,GO:0009987,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	OMP_b-brl_2,OmpA,Transthyretin
TLS3_k127_6654642_1	1484460.JSWG01000011_gene1705	1.625e-52	193.0	COG3391@1|root,COG3391@2|Bacteria,4PKUJ@976|Bacteroidetes,1IJFM@117743|Flavobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_6654642_0	1121889.AUDM01000013_gene1792	1.5e-322	1002.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,1HXMR@117743|Flavobacteriia,2NSAK@237|Flavobacterium	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
TLS3_k127_6655120_5	1305737.JAFX01000001_gene2860	6.824e-68	237.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,47KBG@768503|Cytophagia	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
TLS3_k127_6655120_0	755732.Fluta_2893	1.523e-211	664.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,1HXT4@117743|Flavobacteriia,2PA68@246874|Cryomorphaceae	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
TLS3_k127_6655120_8	616991.JPOO01000003_gene2617	3.149e-30	124.0	COG0399@1|root,COG0399@2|Bacteria,4NUJ4@976|Bacteroidetes,1II66@117743|Flavobacteriia	976|Bacteroidetes	M	30S ribosomal protein S23	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
TLS3_k127_6655120_2	1121098.HMPREF1534_02140	9.147e-133	429.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,2FMNT@200643|Bacteroidia,4AN29@815|Bacteroidaceae	976|Bacteroidetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
TLS3_k127_6655120_1	1267211.KI669560_gene1244	1.853e-198	625.0	COG0427@1|root,COG0427@2|Bacteria,4NFS3@976|Bacteroidetes,1IPAZ@117747|Sphingobacteriia	976|Bacteroidetes	C	acetyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
TLS3_k127_6655120_4	1107311.Q767_00245	1.969e-90	300.0	COG0262@1|root,COG0262@2|Bacteria,4NPJF@976|Bacteroidetes,1I4ZF@117743|Flavobacteriia,2NXEV@237|Flavobacterium	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
TLS3_k127_6655120_11	1313421.JHBV01000022_gene4695	7.713e-08	60.0	2AZZY@1|root,31SA0@2|Bacteria,4NRJ3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6655120_9	1408433.JHXV01000034_gene3	8.637e-14	76.0	2A43C@1|root,30SNC@2|Bacteria,4PABM@976|Bacteroidetes,1ICT7@117743|Flavobacteriia,2PC2U@246874|Cryomorphaceae	976|Bacteroidetes	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
TLS3_k127_6655120_12	1233951.IO90_15185	0.0001561	44.0	COG2220@1|root,COG2220@2|Bacteria,4NENZ@976|Bacteroidetes,1HWY9@117743|Flavobacteriia,3HGWG@358033|Chryseobacterium	976|Bacteroidetes	S	Beta-lactamase superfamily domain	romA	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
TLS3_k127_6655120_13	760192.Halhy_5296	0.0002263	45.0	2CH44@1|root,32S57@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6655120_6	1137281.D778_00550	2.941e-48	179.0	2DM8U@1|root,3273Z@2|Bacteria,4NQC2@976|Bacteroidetes,1I2Y5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6655120_3	1121889.AUDM01000005_gene1758	1.381e-109	378.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,1HX9D@117743|Flavobacteriia,2P01U@237|Flavobacterium	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
TLS3_k127_6655120_7	468059.AUHA01000005_gene2451	1.574e-35	140.0	COG2318@1|root,COG2318@2|Bacteria,4NNJ3@976|Bacteroidetes,1IT0I@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB,DinB_2
TLS3_k127_6677843_1	865937.Gilli_2940	7.666e-134	433.0	COG0604@1|root,COG0604@2|Bacteria,4NHHT@976|Bacteroidetes,1HYRT@117743|Flavobacteriia	976|Bacteroidetes	C	COG0604 NADPH quinone reductase and related Zn-dependent	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_2,ADH_zinc_N_2
TLS3_k127_6677843_0	867902.Ornrh_1744	5.832e-136	445.0	COG3004@1|root,COG3004@2|Bacteria,4NFC4@976|Bacteroidetes,1HXXZ@117743|Flavobacteriia	976|Bacteroidetes	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
TLS3_k127_6677843_2	1131812.JQMS01000001_gene764	1.711e-35	139.0	2CYW5@1|root,32T50@2|Bacteria,4NS73@976|Bacteroidetes,1I3WS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6677843_3	655815.ZPR_2124	1.34e-14	76.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1HZJ8@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter (Permease)	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_6685384_3	485918.Cpin_6574	4.437e-54	194.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,1IQP9@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
TLS3_k127_6685384_1	385682.AFSL01000001_gene1997	3.113e-107	358.0	COG0438@1|root,COG0438@2|Bacteria,4NJ1W@976|Bacteroidetes,2FTR3@200643|Bacteroidia,3XK2C@558415|Marinilabiliaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_6685384_0	1041826.FCOL_12590	1.062e-116	383.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1HWT7@117743|Flavobacteriia,2NSCX@237|Flavobacterium	976|Bacteroidetes	GM	dehydratase	-	-	4.1.1.35,5.1.3.2,5.1.3.7	ko:K01784,ko:K02473,ko:K08678	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R01384,R02984	RC00289,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
TLS3_k127_6685384_2	1124780.ANNU01000002_gene1544	5.865e-102	342.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia	976|Bacteroidetes	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS3_k127_6795660_7	1034807.FBFL15_3021	6.341e-15	83.0	2BTPS@1|root,32NWT@2|Bacteria,4PDCW@976|Bacteroidetes,1ICWU@117743|Flavobacteriia,2NVQJ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
TLS3_k127_6795660_8	755732.Fluta_0563	2.048e-13	71.0	2DNTT@1|root,32Z3E@2|Bacteria,4NVJI@976|Bacteroidetes,1I6BD@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6795660_5	1356852.N008_10650	2.273e-52	194.0	COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,47MB3@768503|Cytophagia	976|Bacteroidetes	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
TLS3_k127_6795660_6	1223410.KN050846_gene888	2.073e-40	153.0	COG1695@1|root,COG1695@2|Bacteria,4NSI4@976|Bacteroidetes,1I2SA@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
TLS3_k127_6795660_2	926562.Oweho_0762	2.738e-85	304.0	COG1983@1|root,COG3256@1|root,COG1983@2|Bacteria,COG3256@2|Bacteria,4NG3T@976|Bacteroidetes,1HX01@117743|Flavobacteriia,2PAXN@246874|Cryomorphaceae	976|Bacteroidetes	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
TLS3_k127_6795660_1	886377.Murru_1865	2.152e-143	461.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1HWPH@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
TLS3_k127_6795660_0	1124780.ANNU01000032_gene1249	2.982e-196	624.0	COG0064@1|root,COG0064@2|Bacteria,4NF3B@976|Bacteroidetes,47K7E@768503|Cytophagia	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
TLS3_k127_6795660_3	1227739.Hsw_2300	2.229e-79	278.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47JZP@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
TLS3_k127_6795660_4	1356852.N008_12795	2.372e-57	206.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
TLS3_k127_6801155_4	1538644.KO02_20775	6.285e-22	100.0	COG2850@1|root,COG2850@2|Bacteria,4NEJI@976|Bacteroidetes,1IPGN@117747|Sphingobacteriia	976|Bacteroidetes	S	A domain family that is part of the cupin metalloenzyme superfamily.	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
TLS3_k127_6801155_2	1218108.KB908291_gene923	1.909e-110	362.0	COG1024@1|root,COG1024@2|Bacteria,4NEH4@976|Bacteroidetes,1HXB6@117743|Flavobacteriia	976|Bacteroidetes	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
TLS3_k127_6801155_0	1121889.AUDM01000006_gene1629	4.849e-177	570.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1HZ6M@117743|Flavobacteriia,2NTIA@237|Flavobacterium	976|Bacteroidetes	C	acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS3_k127_6801155_1	755732.Fluta_2761	1.252e-153	491.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,1HX15@117743|Flavobacteriia,2PAKR@246874|Cryomorphaceae	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
TLS3_k127_6801155_3	945713.IALB_1297	4.412e-88	303.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	ykfB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
TLS3_k127_6804563_0	1453498.LG45_12115	8.77e-82	295.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLH,fn3
TLS3_k127_6804563_1	1408473.JHXO01000013_gene524	9.37e-57	207.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,2FNAY@200643|Bacteroidia	976|Bacteroidetes	S	outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
TLS3_k127_6804563_3	1121097.JCM15093_3118	2.569e-37	143.0	2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,2FTC9@200643|Bacteroidia,4AQY4@815|Bacteroidaceae	976|Bacteroidetes	S	COG NOG14434 non supervised orthologous group	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
TLS3_k127_6804563_2	1121870.AUAA01000013_gene1759	4.754e-48	175.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1HWSS@117743|Flavobacteriia,3HHZI@358033|Chryseobacterium	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
TLS3_k127_6805130_0	869213.JCM21142_52158	3.187e-88	310.0	28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,47M2D@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6811253_4	742766.HMPREF9455_00580	1.979e-27	114.0	arCOG09486@1|root,2ZC3Y@2|Bacteria,4NNUF@976|Bacteroidetes,2FP8A@200643|Bacteroidia	976|Bacteroidetes	S	Glycosyltransferase, family 11	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_11
TLS3_k127_6811253_0	398767.Glov_2747	9.125e-103	358.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1RDAK@1224|Proteobacteria,42U4I@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
TLS3_k127_6811253_1	1121887.AUDK01000019_gene3513	3.039e-78	270.0	COG1215@1|root,COG1215@2|Bacteria,4PKUN@976|Bacteroidetes,1IMP6@117743|Flavobacteriia,2P0TI@237|Flavobacterium	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_6811253_5	59374.Fisuc_1110	2.163e-15	86.0	COG3754@1|root,COG3754@2|Bacteria	2|Bacteria	M	Rhamnan synthesis protein F	-	-	-	ko:K07272,ko:K20444	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_1,RgpF
TLS3_k127_6811253_2	864702.OsccyDRAFT_4934	1.476e-65	235.0	COG1216@1|root,COG1216@2|Bacteria,1G4RU@1117|Cyanobacteria,1HH4K@1150|Oscillatoriales	1117|Cyanobacteria	S	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_6839090_3	391587.KAOT1_17828	1.658e-96	319.0	COG1123@1|root,COG4172@2|Bacteria,4NGDP@976|Bacteroidetes,1HYRD@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the ABC transporter superfamily	gsiA	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
TLS3_k127_6839090_7	714943.Mucpa_3116	5.944e-53	193.0	COG0586@1|root,COG0586@2|Bacteria,4NMBP@976|Bacteroidetes,1IRXI@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
TLS3_k127_6839090_5	1237149.C900_04332	1.063e-72	263.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,47M95@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
TLS3_k127_6839090_2	1408433.JHXV01000001_gene703	5.289e-103	346.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1HZEV@117743|Flavobacteriia,2PC5X@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase family 4	mraY2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
TLS3_k127_6839090_6	153721.MYP_1295	7.11e-71	260.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,47NKW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6839090_1	929562.Emtol_4289	3.309e-151	484.0	COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,47KAF@768503|Cytophagia	976|Bacteroidetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
TLS3_k127_6839090_0	1485544.JQKP01000005_gene418	2.55e-183	579.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,2VIBX@28216|Betaproteobacteria,44VAE@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
TLS3_k127_6839090_9	991.IW20_00445	1.334e-21	97.0	2E6VD@1|root,331EZ@2|Bacteria,4NUSW@976|Bacteroidetes,1I3VV@117743|Flavobacteriia,2NX6W@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF3098)	fjo13	-	-	-	-	-	-	-	-	-	-	-	DUF3098
TLS3_k127_6839090_10	1123277.KB893178_gene2619	8.997e-20	94.0	2AMB7@1|root,31C6A@2|Bacteria,4NQ8I@976|Bacteroidetes,47Q46@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6839090_4	1120966.AUBU01000016_gene3077	2.87e-90	304.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,47KGZ@768503|Cytophagia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
TLS3_k127_6839090_8	886379.AEWI01000014_gene1477	5.102e-35	138.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,2FM17@200643|Bacteroidia,3XJE8@558415|Marinilabiliaceae	976|Bacteroidetes	D	FtsX-like permease family	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
TLS3_k127_6841693_1	1313421.JHBV01000042_gene3261	3.002e-105	363.0	COG2353@1|root,COG3210@1|root,COG2353@2|Bacteria,COG3210@2|Bacteria,4NIDX@976|Bacteroidetes	976|Bacteroidetes	U	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_6841693_0	1296416.JACB01000055_gene3672	1.064e-108	359.0	COG0330@1|root,COG0330@2|Bacteria,4NEBV@976|Bacteroidetes,1HZ2R@117743|Flavobacteriia,2YHHT@290174|Aquimarina	976|Bacteroidetes	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TLS3_k127_6841693_2	1408433.JHXV01000025_gene4026	5.095e-17	81.0	COG4877@1|root,COG4877@2|Bacteria,4NXSU@976|Bacteroidetes,1IGMC@117743|Flavobacteriia,2PC5M@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
TLS3_k127_6856515_4	1121898.Q766_07035	1.126e-114	376.0	COG3746@1|root,COG3746@2|Bacteria,4NG5Z@976|Bacteroidetes,1I77C@117743|Flavobacteriia,2NSHC@237|Flavobacterium	976|Bacteroidetes	P	Pfam Phosphate-selective porin O and P	oprP	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
TLS3_k127_6856515_8	743722.Sph21_0329	4.123e-46	169.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1ITFK@117747|Sphingobacteriia	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
TLS3_k127_6856515_5	926562.Oweho_2671	1.711e-63	231.0	COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,1HXG8@117743|Flavobacteriia,2PAWA@246874|Cryomorphaceae	976|Bacteroidetes	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
TLS3_k127_6856515_6	1121957.ATVL01000011_gene3750	4.471e-52	190.0	COG0526@1|root,COG0526@2|Bacteria,4NM4Y@976|Bacteroidetes,47PPH@768503|Cytophagia	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
TLS3_k127_6856515_2	700598.Niako_4358	9.547e-122	402.0	COG0477@1|root,COG2814@2|Bacteria,4NEUU@976|Bacteroidetes,1INWC@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
TLS3_k127_6856515_1	984262.SGRA_2537	1.225e-192	646.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes	976|Bacteroidetes	DZ	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
TLS3_k127_6856515_11	1313421.JHBV01000049_gene57	1.128e-29	139.0	COG2133@1|root,COG3209@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,CHU_C,Copper-bind,DUF1080,GSDH,PKD,SprB
TLS3_k127_6856515_14	746697.Aeqsu_3225	1.645e-05	59.0	COG2866@1|root,COG3391@1|root,COG2866@2|Bacteria,COG3391@2|Bacteria,4NSJU@976|Bacteroidetes,1I4SR@117743|Flavobacteriia	976|Bacteroidetes	E	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6856515_10	1408433.JHXV01000001_gene693	2.346e-35	145.0	COG3637@1|root,COG3637@2|Bacteria,4NUEN@976|Bacteroidetes,1IC3X@117743|Flavobacteriia,2PB1K@246874|Cryomorphaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_6856515_3	153721.MYP_2706	3.646e-120	392.0	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,47MMI@768503|Cytophagia	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
TLS3_k127_6856515_13	1178825.ALIH01000004_gene2905	2.204e-07	58.0	2DQ1A@1|root,32UNA@2|Bacteria,4NT2M@976|Bacteroidetes,1I4EA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
TLS3_k127_6856515_0	929556.Solca_0511	2.76e-206	674.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,1IRAR@117747|Sphingobacteriia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
TLS3_k127_6856515_9	767817.Desgi_1222	5.446e-38	162.0	COG3391@1|root,COG3391@2|Bacteria,1V6KE@1239|Firmicutes	1239|Firmicutes	DZ	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS3_k127_6856515_12	1089547.KB913013_gene1112	1.343e-11	78.0	COG2133@1|root,COG2373@1|root,COG4625@1|root,COG2133@2|Bacteria,COG2373@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	ko:K12548,ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_3_5,CHU_C,DUF11,GSDH,SWM_repeat,SprB
TLS3_k127_6856515_7	1216967.L100_08839	1.844e-48	177.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1HWSN@117743|Flavobacteriia,34QBA@308865|Elizabethkingia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS3_k127_6858614_1	1123277.KB893174_gene5927	6.592e-87	303.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,47XEG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
TLS3_k127_6858614_2	391603.FBALC1_09522	1.653e-67	237.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1I0QN@117743|Flavobacteriia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_6858614_0	1235813.JCM10003_2390	1.37e-125	409.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,2FMKX@200643|Bacteroidia,4AMQC@815|Bacteroidaceae	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
TLS3_k127_6870813_0	997884.HMPREF1068_00359	1.771e-33	148.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,PPC,Peptidase_M28
TLS3_k127_688586_1	929556.Solca_3727	1.029e-111	372.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1IP5V@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TLS3_k127_688586_0	504472.Slin_2803	3.517e-184	580.0	COG1454@1|root,COG1454@2|Bacteria,4PKHV@976|Bacteroidetes,47NV0@768503|Cytophagia	976|Bacteroidetes	C	Iron-containing alcohol dehydrogenase	-	-	1.1.3.48	ko:K19714	-	-	R11394	RC03427	ko00000,ko01000,ko01005	-	-	-	Fe-ADH
TLS3_k127_688586_3	273121.WS1846	9.244e-69	242.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,42QUH@68525|delta/epsilon subdivisions,2YR3R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
TLS3_k127_688586_4	1237149.C900_01020	7.109e-44	165.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,47QC5@768503|Cytophagia	976|Bacteroidetes	I	Acetyl propionyl-CoA carboxylase alpha subunit	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
TLS3_k127_688586_2	755732.Fluta_1295	7.242e-86	291.0	29UMW@1|root,30FZE@2|Bacteria,4NP3W@976|Bacteroidetes,1IMQI@117743|Flavobacteriia,2PBDZ@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6895563_1	1233950.IW22_13990	1.857e-116	377.0	COG0208@1|root,COG0208@2|Bacteria,4NG18@976|Bacteroidetes,1HXA5@117743|Flavobacteriia	976|Bacteroidetes	F	reductase	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
TLS3_k127_6895563_0	485918.Cpin_1974	0.0	1264.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1IQCA@117747|Sphingobacteriia	976|Bacteroidetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
TLS3_k127_6895563_2	96561.Dole_2560	5.708e-16	81.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,42TA9@68525|delta/epsilon subdivisions,2WPHJ@28221|Deltaproteobacteria,2MKC1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
TLS3_k127_6897118_1	926562.Oweho_2044	1.454e-44	186.0	2EW37@1|root,33PGF@2|Bacteria,4P22D@976|Bacteroidetes,1I7PK@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6897118_0	1313421.JHBV01000032_gene1623	2.963e-196	621.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,1IQPX@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
TLS3_k127_6902556_5	504472.Slin_5884	4.087e-13	75.0	2EVMK@1|root,33P1M@2|Bacteria,4PBBQ@976|Bacteroidetes,47VM3@768503|Cytophagia	976|Bacteroidetes	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
TLS3_k127_6902556_2	760192.Halhy_1712	1.024e-31	129.0	2CIH2@1|root,2ZTG0@2|Bacteria,4NNM2@976|Bacteroidetes,1IZRE@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
TLS3_k127_6902556_3	1086011.HJ01_01776	9.01e-16	84.0	COG2350@1|root,COG2350@2|Bacteria,4NR5W@976|Bacteroidetes,1I5PD@117743|Flavobacteriia,2NU9F@237|Flavobacterium	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6902556_1	313606.M23134_05888	2.401e-32	130.0	COG3324@1|root,COG3324@2|Bacteria,4NMFV@976|Bacteroidetes,47S1F@768503|Cytophagia	976|Bacteroidetes	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS3_k127_6902556_4	755732.Fluta_2561	1.658e-13	79.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_3
TLS3_k127_6902556_0	1122176.KB903563_gene3457	1.711e-99	342.0	COG1262@1|root,COG1262@2|Bacteria,4NKVR@976|Bacteroidetes	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TLS3_k127_6902556_6	313606.M23134_02768	0.0001011	44.0	COG0457@1|root,COG0457@2|Bacteria,4PBAK@976|Bacteroidetes,47VJ2@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6907937_10	1223410.KN050846_gene39	3.02e-06	56.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,4NQIZ@976|Bacteroidetes,1IJKK@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6907937_1	153721.MYP_1357	1.529e-202	638.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,47MI4@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
TLS3_k127_6907937_0	485918.Cpin_6916	3.302e-212	666.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1IQX9@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
TLS3_k127_6907937_8	1123248.KB893339_gene2705	2.069e-30	128.0	295IV@1|root,2ZSWC@2|Bacteria,4NVMA@976|Bacteroidetes,1IZ1W@117747|Sphingobacteriia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6907937_7	1123248.KB893339_gene2708	1.363e-31	126.0	COG1846@1|root,COG1846@2|Bacteria,4PKFS@976|Bacteroidetes,1IZ1N@117747|Sphingobacteriia	976|Bacteroidetes	K	Winged helix DNA-binding domain	marR	-	-	-	-	-	-	-	-	-	-	-	HTH_34
TLS3_k127_6907937_9	700598.Niako_6910	9.695e-23	100.0	2DPXN@1|root,333U2@2|Bacteria,4NWCD@976|Bacteroidetes	976|Bacteroidetes	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
TLS3_k127_6907937_3	1189612.A33Q_3303	1.209e-67	235.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,47P7U@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	gpx1	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
TLS3_k127_6907937_4	484018.BACPLE_01141	1.216e-61	219.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,2FKZG@200643|Bacteroidia,4AMW9@815|Bacteroidaceae	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
TLS3_k127_6907937_5	742766.HMPREF9455_01319	1.086e-41	158.0	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,2FT2Q@200643|Bacteroidia,22Y74@171551|Porphyromonadaceae	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
TLS3_k127_6907937_2	929556.Solca_4106	1.553e-111	368.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,1IPUF@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
TLS3_k127_6913241_0	266748.HY04_07845	1.257e-114	378.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,1HWRS@117743|Flavobacteriia,3ZNK1@59732|Chryseobacterium	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
TLS3_k127_6913241_1	216432.CA2559_04835	6.014e-101	334.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,1HWSV@117743|Flavobacteriia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
TLS3_k127_6913241_2	485918.Cpin_0879	5.323e-74	255.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,1IRD0@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
TLS3_k127_6916002_0	755732.Fluta_1407	1.373e-131	435.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1HX2X@117743|Flavobacteriia,2PA59@246874|Cryomorphaceae	976|Bacteroidetes	P	MgtE intracellular N domain	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
TLS3_k127_6916002_1	509635.N824_02960	8.773e-54	199.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,1IS2N@117747|Sphingobacteriia	976|Bacteroidetes	K	Iron dependent repressor, metal binding and dimerisation domain	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
TLS3_k127_6934434_5	525257.HMPREF0204_13952	4.748e-30	121.0	COG1028@1|root,COG1028@2|Bacteria,4NFXD@976|Bacteroidetes,1HX5Z@117743|Flavobacteriia,3ZR37@59732|Chryseobacterium	976|Bacteroidetes	IQ	Fungal family of unknown function (DUF1776)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_6934434_2	1121899.Q764_08900	6.748e-82	282.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,1HYNK@117743|Flavobacteriia,2NSD3@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
TLS3_k127_6934434_4	216432.CA2559_02540	3.522e-69	245.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,1HYCJ@117743|Flavobacteriia	976|Bacteroidetes	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_6934434_3	509635.N824_18410	2.481e-70	246.0	COG0614@1|root,COG0614@2|Bacteria,4NI2Y@976|Bacteroidetes,1IRZV@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM periplasmic binding protein	fecB	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
TLS3_k127_6934434_1	1123248.KB893386_gene1888	2.777e-133	437.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,1IVHN@117747|Sphingobacteriia	976|Bacteroidetes	P	COG1055 Na H antiporter NhaD and related arsenite	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
TLS3_k127_6934434_0	929556.Solca_0669	1.008e-149	486.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1IQU2@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
TLS3_k127_6934434_6	1453498.LG45_06815	7.911e-18	94.0	COG0810@1|root,COG0810@2|Bacteria,4NG4I@976|Bacteroidetes,1HX6B@117743|Flavobacteriia,2NTPD@237|Flavobacterium	976|Bacteroidetes	M	TonB family domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
TLS3_k127_6934434_7	266762.HQ36_00915	3.692e-05	49.0	COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,2FRY4@200643|Bacteroidia,22Y92@171551|Porphyromonadaceae	976|Bacteroidetes	U	Biopolymer transporter ExbD	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
TLS3_k127_6938590_1	1408473.JHXO01000001_gene2425	2.449e-53	190.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia	976|Bacteroidetes	K	transcriptional regulatory protein	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_6938590_0	755732.Fluta_2725	2.415e-55	224.0	COG3210@1|root,COG3291@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IKDY@117743|Flavobacteriia,2PC6N@246874|Cryomorphaceae	976|Bacteroidetes	U	SPTR Conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA,SprB
TLS3_k127_694816_3	1453500.AT05_00695	2.464e-61	222.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,1HXEV@117743|Flavobacteriia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
TLS3_k127_694816_4	926549.KI421517_gene755	3.78e-11	73.0	COG1388@1|root,COG1388@2|Bacteria,4NPNH@976|Bacteroidetes,47Q7J@768503|Cytophagia	976|Bacteroidetes	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
TLS3_k127_694816_0	1408433.JHXV01000037_gene2573	6.52e-186	610.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY0A@117743|Flavobacteriia,2PBF0@246874|Cryomorphaceae	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
TLS3_k127_694816_1	1117958.PE143B_0119440	8.95e-93	316.0	COG4335@1|root,COG4335@2|Bacteria,1P0C1@1224|Proteobacteria,1RZKS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
TLS3_k127_694816_2	1121481.AUAS01000001_gene4416	1.663e-68	241.0	COG2761@1|root,COG2761@2|Bacteria,4NJ3N@976|Bacteroidetes,47NV7@768503|Cytophagia	976|Bacteroidetes	Q	dithiol-disulfide isomerase involved in polyketide biosynthesis	-	-	5.3.4.1	ko:K01829	-	-	-	-	ko00000,ko01000	-	-	-	DSBA
TLS3_k127_694816_5	1168034.FH5T_22035	3.163e-10	63.0	2APQJ@1|root,31EUD@2|Bacteria,4NNU5@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6968097_1	313606.M23134_07726	2.178e-22	105.0	COG0296@1|root,COG1372@1|root,COG1404@1|root,COG4447@1|root,COG0296@2|Bacteria,COG1372@2|Bacteria,COG1404@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,47PGJ@768503|Cytophagia	976|Bacteroidetes	G	Participates in initiation and elongation during chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Sortilin-Vps10
TLS3_k127_6968097_3	1379698.RBG1_1C00001G1317	0.0003193	53.0	COG1361@1|root,COG3391@1|root,COG1361@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	-
TLS3_k127_6968097_0	1250232.JQNJ01000001_gene3603	1.34e-28	130.0	COG3391@1|root,COG3391@2|Bacteria,4P2SE@976|Bacteroidetes,1I8V8@117743|Flavobacteriia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6968097_2	991.IW20_03575	2.076e-17	91.0	COG1470@1|root,COG3209@1|root,COG3291@1|root,COG1470@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NSSE@237|Flavobacterium	976|Bacteroidetes	O	gliding motility-associated C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB,fn3
TLS3_k127_6969135_2	1034807.FBFL15_1766	2.425e-97	329.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1HX3D@117743|Flavobacteriia,2NT01@237|Flavobacterium	976|Bacteroidetes	S	Exopolyphosphatase	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
TLS3_k127_6969135_0	143224.JQMD01000002_gene1144	6.871e-275	853.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HY0V@117743|Flavobacteriia	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	accD5	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
TLS3_k127_6969135_1	1121897.AUGO01000009_gene2859	6.026e-118	427.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HY32@117743|Flavobacteriia,2NSQ1@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_6969135_3	880071.Fleli_0846	7.334e-47	196.0	COG0457@1|root,COG1196@1|root,COG2208@1|root,COG0457@2|Bacteria,COG1196@2|Bacteria,COG2208@2|Bacteria,4PI8Y@976|Bacteroidetes,47TST@768503|Cytophagia	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	srrB	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	CBS,GAF_2,HAMP,SpoIIE,Y_Y_Y,dCache_1
TLS3_k127_6969135_4	1124780.ANNU01000023_gene3185	1.742e-09	62.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,47RHF@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
TLS3_k127_7025249_0	1121373.KB903626_gene3249	3.801e-113	390.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_7041869_2	1408433.JHXV01000019_gene1947	4.489e-07	52.0	COG1695@1|root,COG1695@2|Bacteria,4NQBA@976|Bacteroidetes,1I39C@117743|Flavobacteriia,2PB1S@246874|Cryomorphaceae	976|Bacteroidetes	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_7041869_0	1408433.JHXV01000028_gene2156	9.381e-99	347.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2PBDM@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
TLS3_k127_7041869_1	1237149.C900_04618	1.035e-18	88.0	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,47JH8@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
TLS3_k127_7049118_9	760192.Halhy_3411	8.174e-54	194.0	COG0640@1|root,COG0640@2|Bacteria,4NS23@976|Bacteroidetes,1IT8B@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_DeoR
TLS3_k127_7049118_11	376686.Fjoh_0081	3.186e-51	184.0	COG0614@1|root,COG0614@2|Bacteria,4NPTQ@976|Bacteroidetes,1I2RW@117743|Flavobacteriia,2NWK1@237|Flavobacterium	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
TLS3_k127_7049118_10	1168034.FH5T_21430	1.077e-51	189.0	COG2253@1|root,COG2253@2|Bacteria,4NPW4@976|Bacteroidetes,2FSGR@200643|Bacteroidia	976|Bacteroidetes	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
TLS3_k127_7049118_13	926556.Echvi_4415	9.789e-31	126.0	COG0250@1|root,COG0250@2|Bacteria,4NSVU@976|Bacteroidetes,47S81@768503|Cytophagia	976|Bacteroidetes	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
TLS3_k127_7049118_7	1196322.A370_05138	2.654e-68	238.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,36I01@31979|Clostridiaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
TLS3_k127_7049118_16	537011.PREVCOP_04148	5.684e-05	46.0	COG0614@1|root,COG0614@2|Bacteria,4NRGG@976|Bacteroidetes,2FT59@200643|Bacteroidia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
TLS3_k127_7049118_15	1492737.FEM08_07260	7.439e-14	73.0	COG0614@1|root,COG0614@2|Bacteria,4NRAK@976|Bacteroidetes,1I3DZ@117743|Flavobacteriia,2NWHH@237|Flavobacterium	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
TLS3_k127_7049118_14	865937.Gilli_2968	8.567e-23	99.0	COG0614@1|root,COG0614@2|Bacteria,4NQY2@976|Bacteroidetes,1I2ZV@117743|Flavobacteriia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
TLS3_k127_7049118_6	367737.Abu_0672	3.863e-69	243.0	COG0107@1|root,COG0107@2|Bacteria,1RA6Q@1224|Proteobacteria,42PND@68525|delta/epsilon subdivisions,2YT8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Histidine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	His_biosynth
TLS3_k127_7049118_4	1123248.KB893314_gene3367	2.516e-112	368.0	COG1682@1|root,COG1682@2|Bacteria,4NF36@976|Bacteroidetes,1IRBJ@117747|Sphingobacteriia	976|Bacteroidetes	GM	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
TLS3_k127_7049118_12	762903.Pedsa_2314	4.06e-34	134.0	COG0399@1|root,COG0399@2|Bacteria,4NVFZ@976|Bacteroidetes,1IUQC@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
TLS3_k127_7049118_3	313606.M23134_02014	2.308e-142	463.0	COG1134@1|root,COG1134@2|Bacteria,4NEDM@976|Bacteroidetes,47JN7@768503|Cytophagia	976|Bacteroidetes	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	rfbB	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
TLS3_k127_7049118_2	313606.M23134_05640	9.118e-175	552.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes,47M4Q@768503|Cytophagia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS3_k127_7049118_1	313606.M23134_05639	5.378e-186	587.0	COG0399@1|root,COG0399@2|Bacteria,4NFQ8@976|Bacteroidetes,47QH2@768503|Cytophagia	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_7049118_5	443143.GM18_1439	3.319e-99	332.0	COG0500@1|root,COG2226@2|Bacteria,1R7KK@1224|Proteobacteria,42TR1@68525|delta/epsilon subdivisions,2WQN2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_7049118_0	1296416.JACB01000017_gene5229	7.492e-312	964.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia,2YGW5@290174|Aquimarina	976|Bacteroidetes	E	Glutamine amidotransferase domain	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS3_k127_7049118_8	367737.Abu_0669	3.788e-61	215.0	COG0110@1|root,COG0110@2|Bacteria,1RFIE@1224|Proteobacteria,42RKV@68525|delta/epsilon subdivisions,2YQXC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
TLS3_k127_7060014_3	362418.IW19_04585	2.764e-47	184.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1HWU2@117743|Flavobacteriia,2NUM8@237|Flavobacterium	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
TLS3_k127_7060014_2	153721.MYP_1562	2.213e-133	432.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,47K59@768503|Cytophagia	976|Bacteroidetes	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
TLS3_k127_7060014_0	1408433.JHXV01000001_gene1081	1.912e-178	577.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1HXQU@117743|Flavobacteriia,2PBAM@246874|Cryomorphaceae	976|Bacteroidetes	I	AMP-binding enzyme	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
TLS3_k127_7060014_1	1121904.ARBP01000004_gene824	5.463e-141	453.0	COG0451@1|root,COG0451@2|Bacteria,4NIZG@976|Bacteroidetes,47KEK@768503|Cytophagia	976|Bacteroidetes	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
TLS3_k127_7061444_1	929703.KE386491_gene1561	3.256e-08	57.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,47KKB@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
TLS3_k127_7061444_0	1123008.KB905695_gene2524	8.437e-185	594.0	COG0793@1|root,COG0793@2|Bacteria,4NEK8@976|Bacteroidetes,2FNHK@200643|Bacteroidia,22XCW@171551|Porphyromonadaceae	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
TLS3_k127_7098747_2	927658.AJUM01000037_gene2150	2.533e-18	93.0	COG0806@1|root,COG0806@2|Bacteria,4NQF0@976|Bacteroidetes,2FMK1@200643|Bacteroidia,3XKAB@558415|Marinilabiliaceae	976|Bacteroidetes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
TLS3_k127_7098747_0	742817.HMPREF9449_01867	9.977e-255	795.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,2FMC4@200643|Bacteroidia,22XB9@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
TLS3_k127_7098747_1	1227739.Hsw_0809	4.493e-67	232.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,47J92@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	eryC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_7107214_2	63737.Npun_F1378	2.603e-42	163.0	COG0500@1|root,COG0500@2|Bacteria,1GGJB@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7107214_1	536227.CcarbDRAFT_3046	9.971e-114	379.0	COG0438@1|root,COG0438@2|Bacteria,1UTQH@1239|Firmicutes,24BT3@186801|Clostridia,36F7W@31979|Clostridiaceae	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_7107214_0	926549.KI421517_gene119	4.888e-165	541.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,47M0A@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
TLS3_k127_7108622_7	926562.Oweho_0192	1.499e-18	89.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
TLS3_k127_7108622_6	411154.GFO_1810	3.892e-44	170.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,1HZIC@117743|Flavobacteriia	976|Bacteroidetes	S	NADP oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
TLS3_k127_7108622_4	1250006.JHZZ01000001_gene2866	7.746e-59	208.0	COG1778@1|root,COG1778@2|Bacteria,4NMHD@976|Bacteroidetes,1I1FS@117743|Flavobacteriia,3VVWY@52959|Polaribacter	976|Bacteroidetes	S	haloacid dehalogenase-like hydrolase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_3
TLS3_k127_7108622_5	385682.AFSL01000019_gene2220	5.3e-50	190.0	COG0382@1|root,COG0382@2|Bacteria,4NFRM@976|Bacteroidetes,2FSPD@200643|Bacteroidia,3XIQE@558415|Marinilabiliaceae	976|Bacteroidetes	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
TLS3_k127_7108622_3	1121897.AUGO01000014_gene3437	7.613e-59	210.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,1I17Y@117743|Flavobacteriia,2NSDZ@237|Flavobacterium	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
TLS3_k127_7108622_8	926562.Oweho_0590	5.96e-14	85.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TLS3_k127_7108622_2	745718.JADT01000007_gene2691	5.278e-66	231.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,1HYB1@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase, M22	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
TLS3_k127_7108622_1	468059.AUHA01000002_gene1366	5.788e-115	385.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1IRGW@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
TLS3_k127_7108622_0	1380600.AUYN01000009_gene990	4.025e-214	684.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1HWWU@117743|Flavobacteriia	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_127,Glyco_hydro_76,Thioredox_DsbH
TLS3_k127_7112575_8	1131812.JQMS01000001_gene2028	1.106e-17	83.0	COG5002@1|root,COG5002@2|Bacteria,4PKIV@976|Bacteroidetes,1HXTU@117743|Flavobacteriia,2NU8K@237|Flavobacterium	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9
TLS3_k127_7112575_5	1189620.AJXL01000022_gene2879	1.103e-89	299.0	COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,1I18C@117743|Flavobacteriia,2NWAP@237|Flavobacterium	976|Bacteroidetes	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_7112575_0	1131812.JQMS01000001_gene2390	0.0	1039.0	COG0642@1|root,COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,4NDXU@976|Bacteroidetes,1HYZK@117743|Flavobacteriia,2NUWE@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_7112575_6	1189620.AJXL01000022_gene2877	6.235e-64	221.0	COG0745@1|root,COG0745@2|Bacteria,4PP1Z@976|Bacteroidetes,1IN3P@117743|Flavobacteriia,2NWFJ@237|Flavobacterium	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_7112575_7	760192.Halhy_5646	1.862e-29	135.0	COG5184@1|root,COG5184@2|Bacteria,4NK5Z@976|Bacteroidetes	976|Bacteroidetes	DMZ	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494
TLS3_k127_7112575_4	1123057.P872_04435	5.596e-163	531.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_1,Big_3_2,Big_5,Cadherin-like,DUF3494,TIG
TLS3_k127_7112575_1	1131812.JQMS01000001_gene2355	4.88e-269	844.0	COG2885@1|root,COG2885@2|Bacteria,4NI1Y@976|Bacteroidetes,1ICVE@117743|Flavobacteriia,2NV7K@237|Flavobacterium	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2,OmpA
TLS3_k127_7112575_3	1121287.AUMU01000005_gene3183	1.862e-172	556.0	COG2373@1|root,COG2373@2|Bacteria,4NTMR@976|Bacteroidetes	976|Bacteroidetes	M	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3494
TLS3_k127_7112575_2	1189620.AJXL01000074_gene3244	2.275e-176	595.0	COG1345@1|root,COG1361@1|root,COG1520@1|root,COG3291@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG1520@2|Bacteria,COG3291@2|Bacteria,4NEZF@976|Bacteroidetes,1HZ6F@117743|Flavobacteriia,2NSYB@237|Flavobacterium	976|Bacteroidetes	N	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7159586_0	1123057.P872_22895	1.641e-213	682.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,47K9H@768503|Cytophagia	976|Bacteroidetes	L	DNA-directed DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
TLS3_k127_7159586_1	762903.Pedsa_3218	2.695e-85	310.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,1INT0@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
TLS3_k127_7159586_2	762903.Pedsa_3313	3.351e-14	74.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,1IP4G@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
TLS3_k127_7162188_6	926549.KI421517_gene2047	4.612e-96	320.0	COG0407@1|root,COG0407@2|Bacteria,4NEQ7@976|Bacteroidetes,47K90@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
TLS3_k127_7162188_10	1450525.JATV01000022_gene1517	1.213e-65	230.0	COG0702@1|root,COG0702@2|Bacteria,4NG89@976|Bacteroidetes,1I18P@117743|Flavobacteriia,2NVI0@237|Flavobacterium	976|Bacteroidetes	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
TLS3_k127_7162188_0	468059.AUHA01000002_gene1108	4.236e-308	952.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1IQXV@117747|Sphingobacteriia	976|Bacteroidetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
TLS3_k127_7162188_15	1313421.JHBV01000025_gene995	2.503e-18	85.0	COG0640@1|root,COG0640@2|Bacteria,4NS8H@976|Bacteroidetes	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
TLS3_k127_7162188_17	1506583.JQJY01000003_gene3649	1.275e-05	47.0	COG0640@1|root,COG0640@2|Bacteria,4NS8H@976|Bacteroidetes,1I4BK@117743|Flavobacteriia,2NWPP@237|Flavobacterium	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
TLS3_k127_7162188_13	1121896.JMLU01000001_gene1121	3.887e-44	169.0	COG5658@1|root,COG5658@2|Bacteria,4NNCF@976|Bacteroidetes,1I1PF@117743|Flavobacteriia,2NU47@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
TLS3_k127_7162188_2	926549.KI421517_gene3971	6.668e-193	612.0	COG1875@1|root,COG1875@2|Bacteria,4NDUI@976|Bacteroidetes,47M94@768503|Cytophagia	976|Bacteroidetes	T	PIN domain	ybeZ_1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
TLS3_k127_7162188_3	391596.PBAL39_23372	7.671e-143	470.0	COG0181@1|root,COG1587@1|root,COG0181@2|Bacteria,COG1587@2|Bacteria,4NHH4@976|Bacteroidetes,1ISWJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
TLS3_k127_7162188_11	1227739.Hsw_3729	2.288e-60	211.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,47PPG@768503|Cytophagia	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
TLS3_k127_7162188_4	243233.MCA1772	2.797e-136	449.0	COG2244@1|root,COG2244@2|Bacteria,1R512@1224|Proteobacteria,1RZ0F@1236|Gammaproteobacteria,1XE8D@135618|Methylococcales	135618|Methylococcales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
TLS3_k127_7162188_5	926562.Oweho_1411	2.63e-112	371.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1HXB2@117743|Flavobacteriia,2PAPS@246874|Cryomorphaceae	976|Bacteroidetes	M	Male sterility protein	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
TLS3_k127_7162188_7	929562.Emtol_3528	2.194e-76	260.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,47NCP@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
TLS3_k127_7162188_16	526218.Sterm_1869	1.809e-06	59.0	COG0834@1|root,COG0834@2|Bacteria,37APB@32066|Fusobacteria	32066|Fusobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
TLS3_k127_7162188_12	1124780.ANNU01000090_gene323	1.119e-54	197.0	28NIX@1|root,2ZBK6@2|Bacteria,4NMEI@976|Bacteroidetes,47MBS@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2480)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2480
TLS3_k127_7162188_9	1353276.JADR01000007_gene1462	5.437e-66	231.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1I1F1@117743|Flavobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	pgdA_1	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
TLS3_k127_7162188_1	869213.JCM21142_104129	9.07e-292	930.0	COG0038@1|root,COG0038@2|Bacteria,4NZYS@976|Bacteroidetes	976|Bacteroidetes	P	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
TLS3_k127_7162188_8	1121890.AUDO01000019_gene1042	2.592e-75	290.0	COG1361@1|root,COG2911@1|root,COG4733@1|root,COG5434@1|root,COG1361@2|Bacteria,COG2911@2|Bacteria,COG4733@2|Bacteria,COG5434@2|Bacteria,4NMB8@976|Bacteroidetes,1IJ89@117743|Flavobacteriia,2P0KP@237|Flavobacterium	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG
TLS3_k127_7162188_14	1089547.KB913013_gene1107	1.613e-36	162.0	COG2373@1|root,COG3291@1|root,COG2373@2|Bacteria,COG3291@2|Bacteria,4NJQN@976|Bacteroidetes,47QVQ@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,IgGFc_binding,PKD,SprB,fn3
TLS3_k127_7162188_18	1094466.KQS_00305	0.0004764	55.0	COG4409@1|root,COG4409@2|Bacteria,4PM7K@976|Bacteroidetes,1IJKJ@117743|Flavobacteriia,2NTU2@237|Flavobacterium	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10,fn3
TLS3_k127_7163599_1	1227739.Hsw_3607	2.569e-10	73.0	COG3307@1|root,COG3307@2|Bacteria,4NU0S@976|Bacteroidetes,47R1I@768503|Cytophagia	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
TLS3_k127_7163599_2	313606.M23134_05624	7.41e-09	68.0	COG3307@1|root,COG3307@2|Bacteria,4NUP9@976|Bacteroidetes,47V2J@768503|Cytophagia	976|Bacteroidetes	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
TLS3_k127_7163599_0	929556.Solca_1909	5.306e-73	250.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1IQ8E@117747|Sphingobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
TLS3_k127_7191993_4	755732.Fluta_2725	4.883e-73	276.0	COG3210@1|root,COG3291@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IKDY@117743|Flavobacteriia,2PC6N@246874|Cryomorphaceae	976|Bacteroidetes	U	SPTR Conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA,SprB
TLS3_k127_7191993_14	596151.DesfrDRAFT_0866	3.86e-06	51.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW7X@1224|Proteobacteria,42Q11@68525|delta/epsilon subdivisions,2WKFK@28221|Deltaproteobacteria,2MF6S@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
TLS3_k127_7191993_13	1453500.AT05_01420	3.725e-11	65.0	COG2801@1|root,COG2801@2|Bacteria,4NIBY@976|Bacteroidetes,1HY8E@117743|Flavobacteriia	976|Bacteroidetes	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
TLS3_k127_7191993_10	1453500.AT05_01420	3.818e-19	89.0	COG2801@1|root,COG2801@2|Bacteria,4NIBY@976|Bacteroidetes,1HY8E@117743|Flavobacteriia	976|Bacteroidetes	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
TLS3_k127_7191993_9	1453500.AT05_01425	6.958e-29	118.0	COG2963@1|root,COG2963@2|Bacteria,4NWB6@976|Bacteroidetes,1I5Y6@117743|Flavobacteriia	976|Bacteroidetes	L	transposase IS3 IS911 family protein	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
TLS3_k127_7191993_15	1237149.C900_01218	0.0004353	44.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,4NM4S@976|Bacteroidetes,47PK6@768503|Cytophagia	976|Bacteroidetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
TLS3_k127_7191993_6	1086011.HJ01_00318	2.068e-58	205.0	COG1898@1|root,COG1898@2|Bacteria,4PKN3@976|Bacteroidetes,1I2XR@117743|Flavobacteriia,2NZ40@237|Flavobacterium	976|Bacteroidetes	M	WxcM-like, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	FdtA
TLS3_k127_7191993_5	929556.Solca_4315	8.8e-59	206.0	COG0662@1|root,COG0662@2|Bacteria,4NQ4K@976|Bacteroidetes,1IUC6@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM WxcM-like, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	FdtA
TLS3_k127_7191993_12	987059.RBXJA2T_13744	1.567e-16	82.0	2ENSD@1|root,33GDJ@2|Bacteria,1NGWW@1224|Proteobacteria,2VXQ3@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7191993_3	987059.RBXJA2T_13739	8.129e-75	258.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,1KJXH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	reductase	-	-	1.1.1.100,1.1.1.47	ko:K00034,ko:K00059	ko00030,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00030,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00572	R01520,R01521,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00066,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_7191993_8	987059.RBXJA2T_13734	7.926e-40	156.0	COG0491@1|root,COG0491@2|Bacteria,1RJ30@1224|Proteobacteria,2W4XA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_7191993_2	987059.RBXJA2T_13729	1.423e-101	340.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2VI2A@28216|Betaproteobacteria,1KJ68@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
TLS3_k127_7191993_7	357804.Ping_1633	2.372e-43	170.0	COG2227@1|root,COG3882@1|root,COG2227@2|Bacteria,COG3882@2|Bacteria,1PNPC@1224|Proteobacteria,1RSDT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	enzyme involved in methoxymalonyl-ACP biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS3_k127_7191993_1	1047013.AQSP01000144_gene878	2.131e-146	473.0	COG1028@1|root,COG2030@1|root,COG1028@2|Bacteria,COG2030@2|Bacteria,2NP35@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,4.2.1.55	ko:K00059,ko:K17865	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R03027,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00831	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	MaoC_dehydratas,adh_short_C2
TLS3_k127_7191993_0	1047013.AQSP01000144_gene879	1.601e-163	533.0	COG3882@1|root,COG3882@2|Bacteria	2|Bacteria	Q	phosphopantetheine binding	-	-	-	-	-	-	-	-	-	-	-	-	NIF
TLS3_k127_7191993_11	1047013.AQSP01000144_gene880	2.025e-17	83.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TLS3_k127_7193913_0	929562.Emtol_2590	0.0	1105.0	COG1538@1|root,COG3696@1|root,COG1538@2|Bacteria,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,47JC4@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
TLS3_k127_7193913_3	929562.Emtol_2591	3.64e-22	101.0	2EAT9@1|root,338DK@2|Bacteria,4NVJP@976|Bacteroidetes,47T8C@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7193913_4	1121286.AUMT01000003_gene2015	9.599e-22	100.0	COG3212@1|root,COG3212@2|Bacteria,4P9D8@976|Bacteroidetes,1IEMY@117743|Flavobacteriia,3ZT0W@59732|Chryseobacterium	976|Bacteroidetes	S	Putative beta-lactamase-inhibitor-like, PepSY-like	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_like
TLS3_k127_7193913_2	313594.PI23P_05117	1.77e-99	329.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia,3VVR4@52959|Polaribacter	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_7193913_1	1453498.LG45_10680	6.825e-156	516.0	COG1629@1|root,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,1HXUT@117743|Flavobacteriia,2NTWY@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug,TonB_dep_Rec
TLS3_k127_7199715_0	1107311.Q767_14915	4.367e-18	87.0	2CWBN@1|root,32SZD@2|Bacteria,4NU6S@976|Bacteroidetes,1I6B8@117743|Flavobacteriia,2NW45@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7199715_1	1202532.FF52_07394	6.298e-16	81.0	2DRR4@1|root,33CQD@2|Bacteria,4P6IM@976|Bacteroidetes,1ICNX@117743|Flavobacteriia,2NTWX@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
TLS3_k127_7213007_0	391603.FBALC1_09917	2.747e-05	55.0	COG1520@1|root,COG4886@1|root,COG1520@2|Bacteria,COG4886@2|Bacteria,4NJHN@976|Bacteroidetes,1HZTN@117743|Flavobacteriia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7228044_2	926562.Oweho_0717	1.627e-84	293.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,1IEBF@117743|Flavobacteriia,2PB0Z@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
TLS3_k127_7228044_1	1227739.Hsw_1967	8.782e-85	296.0	COG1215@1|root,COG1215@2|Bacteria,4NEG0@976|Bacteroidetes,47KET@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_7228044_0	926562.Oweho_0344	1.282e-93	325.0	COG1934@1|root,COG1934@2|Bacteria,4PKT4@976|Bacteroidetes,1IKDV@117743|Flavobacteriia,2PAQU@246874|Cryomorphaceae	976|Bacteroidetes	S	OstA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OstA_2
TLS3_k127_7228044_3	1453500.AT05_07335	7.781e-69	238.0	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,1HZ1Y@117743|Flavobacteriia	976|Bacteroidetes	I	thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
TLS3_k127_7228044_5	468059.AUHA01000008_gene2744	1.781e-43	165.0	COG1981@1|root,COG1981@2|Bacteria,4NEWG@976|Bacteroidetes,1IS6G@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
TLS3_k127_7228044_6	1123035.ARLA01000028_gene2033	2.351e-30	134.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes,1HYQM@117743|Flavobacteriia,4C2NI@83612|Psychroflexus	976|Bacteroidetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
TLS3_k127_7228044_4	1237149.C900_02393	4.907e-47	180.0	2AFYA@1|root,31622@2|Bacteria,4P4XX@976|Bacteroidetes,47VB7@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1571)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1571,LysM
TLS3_k127_7228044_7	1189612.A33Q_3635	2.983e-06	57.0	298K1@1|root,2ZVQX@2|Bacteria,4NNNX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_72617_0	1353276.JADR01000001_gene661	1.671e-102	347.0	COG4487@1|root,COG4487@2|Bacteria,4NGZ9@976|Bacteroidetes,1HZ50@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2130
TLS3_k127_72617_4	1443665.JACA01000001_gene2533	1.723e-05	51.0	2C99J@1|root,300A4@2|Bacteria,4PH8Q@976|Bacteroidetes,1IHYA@117743|Flavobacteriia,2YK7F@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_72617_1	391587.KAOT1_03737	1.022e-57	217.0	2C8K2@1|root,33RA7@2|Bacteria,4P1C9@976|Bacteroidetes,1I77M@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_72617_3	1174504.AJTN02000176_gene2071	6.569e-08	55.0	29S7Z@1|root,30DCG@2|Bacteria,1UB50@1239|Firmicutes,4IMHI@91061|Bacilli,1ZK63@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_72617_2	1313421.JHBV01000027_gene1774	3.11e-35	156.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1IZUU@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
TLS3_k127_726945_3	1248232.BANQ01000122_gene594	7.033e-20	95.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,1S866@1236|Gammaproteobacteria,1Y2G9@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_726945_0	1121904.ARBP01000006_gene3902	1.793e-49	194.0	28KRY@1|root,2ZA9E@2|Bacteria,4NI1H@976|Bacteroidetes,47N4R@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_726945_2	153721.MYP_993	1.784e-28	119.0	COG0784@1|root,COG0784@2|Bacteria,4NRC9@976|Bacteroidetes,47QC7@768503|Cytophagia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_726945_4	1306174.JODP01000001_gene4822	1.333e-07	64.0	COG5002@1|root,COG5002@2|Bacteria,2I42Z@201174|Actinobacteria	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
TLS3_k127_726945_1	1341181.FLJC2902T_26920	3.203e-40	167.0	COG2202@1|root,COG4251@1|root,COG5000@1|root,COG5002@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,4NI5R@976|Bacteroidetes,1IKW5@117743|Flavobacteriia,2P01K@237|Flavobacterium	976|Bacteroidetes	T	Four helix bundle sensory module for signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_9
TLS3_k127_727000_2	1123393.KB891317_gene2438	1.069e-13	71.0	COG0642@1|root,COG4251@1|root,COG2205@2|Bacteria,COG4251@2|Bacteria,1NRP8@1224|Proteobacteria,2WHET@28216|Betaproteobacteria,1KSI3@119069|Hydrogenophilales	1224|Proteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,MASE4,PAS,PAS_3,PAS_9,Response_reg
TLS3_k127_727000_1	1408433.JHXV01000024_gene1495	1.038e-15	92.0	COG1361@1|root,COG2911@1|root,COG3209@1|root,COG1361@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,4NKIP@976|Bacteroidetes	976|Bacteroidetes	U	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,Gal_Lectin
TLS3_k127_727000_0	1123248.KB893339_gene2712	1.558e-151	514.0	COG2373@1|root,COG3391@1|root,COG2373@2|Bacteria,COG3391@2|Bacteria,4NTMR@976|Bacteroidetes	976|Bacteroidetes	M	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3494
TLS3_k127_7278686_0	1237149.C900_01769	3.442e-301	935.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,47KFY@768503|Cytophagia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
TLS3_k127_7278686_2	760192.Halhy_1375	2.939e-127	415.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,1IQZT@117747|Sphingobacteriia	976|Bacteroidetes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
TLS3_k127_7278686_3	1121889.AUDM01000004_gene2555	7.638e-100	335.0	COG2855@1|root,COG2855@2|Bacteria,4NES6@976|Bacteroidetes,1HYZF@117743|Flavobacteriia,2NT77@237|Flavobacterium	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
TLS3_k127_7278686_6	1089547.KB913013_gene1112	6.116e-14	85.0	COG2133@1|root,COG2373@1|root,COG4625@1|root,COG2133@2|Bacteria,COG2373@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	ko:K12548,ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_3_5,CHU_C,DUF11,GSDH,SWM_repeat,SprB
TLS3_k127_7278686_5	762903.Pedsa_2409	1.324e-41	174.0	COG2911@1|root,COG3210@1|root,COG4625@1|root,COG5492@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG5492@2|Bacteria,4NHHA@976|Bacteroidetes	976|Bacteroidetes	E	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_4,CHU_C,Calx-beta,He_PIG,NHL,TIG,fn3
TLS3_k127_7278686_1	1454007.JAUG01000018_gene1572	1.578e-179	585.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1IR9Y@117747|Sphingobacteriia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
TLS3_k127_7278686_4	1122621.ATZA01000005_gene636	1.714e-85	285.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1IPN7@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
TLS3_k127_7365533_2	755732.Fluta_1117	3.471e-50	181.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1HWVA@117743|Flavobacteriia,2PAC5@246874|Cryomorphaceae	976|Bacteroidetes	M	TIGRFAM outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
TLS3_k127_7365533_3	926549.KI421517_gene385	6.685e-48	179.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,47PD1@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane protein (OmpH-like)	skp	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TLS3_k127_7365533_4	743722.Sph21_5199	6.313e-19	94.0	COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,1ITN8@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM outer membrane chaperone Skp (OmpH)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TLS3_k127_7365533_1	1120965.AUBV01000014_gene1238	1.813e-80	277.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,4NERC@976|Bacteroidetes,47K07@768503|Cytophagia	976|Bacteroidetes	K	PFAM MerR family regulatory protein	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
TLS3_k127_7365533_0	1123008.KB905696_gene2890	1.206e-248	774.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,2FM9D@200643|Bacteroidia,22WDE@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
TLS3_k127_7373431_3	1122621.ATZA01000010_gene160	0.0001086	45.0	COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,1IRXR@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
TLS3_k127_7373431_2	641526.ADIWIN_2498	1.793e-10	72.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1HYE4@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_7373431_0	1168034.FH5T_17555	9.64e-83	285.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,2FP92@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
TLS3_k127_7373431_1	1121889.AUDM01000014_gene1966	1.162e-81	280.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1HWSS@117743|Flavobacteriia,2NSP7@237|Flavobacterium	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
TLS3_k127_7381168_2	926549.KI421517_gene3088	4.331e-68	239.0	COG3021@1|root,COG3021@2|Bacteria,4PKDH@976|Bacteroidetes	976|Bacteroidetes	S	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_7381168_0	1229276.DI53_0901	4.338e-236	736.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1IQG6@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_7381168_1	1121904.ARBP01000004_gene939	3.252e-108	366.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,47M1B@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_7403237_2	1296415.JACC01000019_gene3758	2.08e-91	309.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,1HXKT@117743|Flavobacteriia,2YHEY@290174|Aquimarina	976|Bacteroidetes	J	Isopentenyl transferase	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
TLS3_k127_7403237_3	1168034.FH5T_15130	1.461e-75	273.0	COG2755@1|root,COG2755@2|Bacteria,4NHT6@976|Bacteroidetes,2G37X@200643|Bacteroidia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
TLS3_k127_7403237_4	1519464.HY22_07700	7.473e-67	243.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	Z012_00180	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL,Lipase_GDSL_2,LysM
TLS3_k127_7403237_0	1168034.FH5T_15140	1.504e-176	569.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,2FM3F@200643|Bacteroidia	976|Bacteroidetes	M	Psort location CytoplasmicMembrane, score 10.00	algI	-	-	-	-	-	-	-	-	-	-	-	MBOAT
TLS3_k127_7403237_1	1237149.C900_05256	5.801e-120	399.0	COG1131@1|root,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,47KQD@768503|Cytophagia	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,TerB
TLS3_k127_7411841_3	1121864.OMO_01868	3.436e-15	78.0	COG2153@1|root,COG2153@2|Bacteria,1VAJY@1239|Firmicutes,4HIH7@91061|Bacilli,4B2R2@81852|Enterococcaceae	91061|Bacilli	S	Acetyltransferase (GNAT) domain	yybD	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
TLS3_k127_7411841_2	1185876.BN8_04801	2.471e-40	152.0	COG1832@1|root,COG1832@2|Bacteria,4NSE8@976|Bacteroidetes,47RGM@768503|Cytophagia	976|Bacteroidetes	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
TLS3_k127_7411841_0	468059.AUHA01000003_gene1846	1.37e-122	406.0	COG0477@1|root,COG2814@2|Bacteria,4NEQU@976|Bacteroidetes,1IP74@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_7411841_1	1123248.KB893326_gene1308	3.282e-106	364.0	COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,1IVJP@117747|Sphingobacteriia	976|Bacteroidetes	O	S53, subtilisin kexin sedolisin	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_7419506_2	1356852.N008_17150	1.176e-20	94.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,47QER@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
TLS3_k127_7419506_1	886377.Murru_0474	7.666e-71	248.0	COG1624@1|root,COG1624@2|Bacteria,4NG3Z@976|Bacteroidetes,1HWTY@117743|Flavobacteriia	976|Bacteroidetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
TLS3_k127_7419506_0	655815.ZPR_1912	3.011e-94	318.0	COG0248@1|root,COG0248@2|Bacteria,4NEI0@976|Bacteroidetes,1HX36@117743|Flavobacteriia	976|Bacteroidetes	FP	exopolyphosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
TLS3_k127_7419506_3	485918.Cpin_3685	3.262e-16	81.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1IPGC@117747|Sphingobacteriia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
TLS3_k127_7455903_3	1123033.ARNF01000087_gene1476	1.305e-52	189.0	COG0732@1|root,COG0732@2|Bacteria,1MXSQ@1224|Proteobacteria,1S320@1236|Gammaproteobacteria,3NNQM@468|Moraxellaceae	1236|Gammaproteobacteria	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
TLS3_k127_7455903_4	1507.HMPREF0262_00923	4.655e-24	118.0	COG3593@1|root,COG3593@2|Bacteria,1V5E5@1239|Firmicutes,24PX8@186801|Clostridia	186801|Clostridia	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
TLS3_k127_7455903_2	517418.Ctha_0805	2.26e-158	507.0	COG3177@1|root,COG3177@2|Bacteria,1FE4V@1090|Chlorobi	1090|Chlorobi	S	PFAM filamentation induced by cAMP protein Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
TLS3_k127_7455903_0	1120951.AUBG01000005_gene2172	2.342e-249	779.0	COG0286@1|root,COG0286@2|Bacteria,4NG0E@976|Bacteroidetes,1HYSD@117743|Flavobacteriia	976|Bacteroidetes	V	type I restriction-modification system	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
TLS3_k127_7455903_1	762903.Pedsa_3478	3.713e-209	663.0	COG1032@1|root,COG1032@2|Bacteria,4NJAN@976|Bacteroidetes	976|Bacteroidetes	C	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
TLS3_k127_7460402_2	1408433.JHXV01000006_gene2725	7.061e-62	218.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1HXT1@117743|Flavobacteriia,2PAQC@246874|Cryomorphaceae	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
TLS3_k127_7460402_0	1408433.JHXV01000011_gene2002	3.495e-170	544.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1HWY8@117743|Flavobacteriia,2PAF8@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
TLS3_k127_7460402_3	755732.Fluta_0073	1.539e-26	113.0	COG2346@1|root,COG2346@2|Bacteria,4NVGJ@976|Bacteroidetes,1I53B@117743|Flavobacteriia	976|Bacteroidetes	S	COG2346, Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
TLS3_k127_7460402_4	1185876.BN8_05395	5.604e-07	58.0	COG1595@1|root,COG1595@2|Bacteria,4NN2T@976|Bacteroidetes,47P7Q@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_7460402_1	883096.HMPREF9699_00130	3.18e-100	328.0	COG0208@1|root,COG0208@2|Bacteria,4NG18@976|Bacteroidetes,1HXA5@117743|Flavobacteriia	976|Bacteroidetes	F	reductase	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
TLS3_k127_746748_0	929556.Solca_2743	5.155e-181	588.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,4NERV@976|Bacteroidetes,1IQ79@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
TLS3_k127_746748_7	700598.Niako_7317	4.44e-21	98.0	2ADW0@1|root,313N0@2|Bacteria,4NSUW@976|Bacteroidetes,1ITPF@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_746748_2	709991.Odosp_1354	1.452e-102	342.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,2FMPT@200643|Bacteroidia,22W13@171551|Porphyromonadaceae	976|Bacteroidetes	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
TLS3_k127_746748_4	1453498.LG45_00520	1.817e-41	158.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,1I198@117743|Flavobacteriia,2NTX5@237|Flavobacterium	976|Bacteroidetes	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
TLS3_k127_746748_5	1121931.AUHG01000010_gene406	2.139e-34	134.0	29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,1I1Z8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_746748_3	1121870.AUAA01000013_gene1698	1.323e-64	227.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,1HXAB@117743|Flavobacteriia,3HHD4@358033|Chryseobacterium	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
TLS3_k127_746748_1	525373.HMPREF0766_11560	4.007e-125	408.0	COG3176@1|root,COG3176@2|Bacteria,4PKEK@976|Bacteroidetes,1IPDS@117747|Sphingobacteriia	976|Bacteroidetes	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
TLS3_k127_746748_6	1270196.JCKI01000003_gene2250	3.787e-22	106.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_7487339_3	388413.ALPR1_17873	8.292e-37	141.0	2EFQE@1|root,339GD@2|Bacteria,4NWTN@976|Bacteroidetes,47VGD@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7487339_1	326442.PSHAa1036	5.842e-41	161.0	2C3WA@1|root,2Z8P1@2|Bacteria,1R8VC@1224|Proteobacteria,1S5UD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7487339_0	1107311.Q767_00245	4.29e-90	301.0	COG0262@1|root,COG0262@2|Bacteria,4NPJF@976|Bacteroidetes,1I4ZF@117743|Flavobacteriia,2NXEV@237|Flavobacterium	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
TLS3_k127_7487339_4	1313421.JHBV01000026_gene445	8.436e-31	141.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
TLS3_k127_7487339_2	1107311.Q767_08430	2.173e-37	148.0	2BVHW@1|root,30Z9V@2|Bacteria,4PDF6@976|Bacteroidetes,1IDXE@117743|Flavobacteriia,2NZES@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7491947_1	1250232.JQNJ01000001_gene3453	1.804e-07	60.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1HY1W@117743|Flavobacteriia	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
TLS3_k127_7491947_0	755732.Fluta_3847	6.239e-82	286.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	srrB	-	-	-	-	-	-	-	-	-	-	-	CBS,HAMP,SpoIIE,dCache_1
TLS3_k127_7502065_3	1358423.N180_11935	1.992e-49	178.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1INW4@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_7502065_0	926562.Oweho_2827	1.233e-185	588.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1HWY5@117743|Flavobacteriia,2PAGT@246874|Cryomorphaceae	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
TLS3_k127_7502065_1	468059.AUHA01000004_gene2174	1.998e-182	580.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1INPJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
TLS3_k127_7502065_2	1122605.KB893630_gene4063	1.188e-64	231.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1IPWG@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
TLS3_k127_7504530_0	1046627.BZARG_1122	7.2e-93	327.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,1HWXQ@117743|Flavobacteriia	976|Bacteroidetes	L	COG3893 Inactivated superfamily I helicase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
TLS3_k127_7508523_4	1189612.A33Q_1443	9.925e-47	173.0	2EX4T@1|root,33QFU@2|Bacteria,4P0AC@976|Bacteroidetes,47TMJ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7508523_1	926549.KI421517_gene1683	4.84e-116	381.0	COG1363@1|root,COG1363@2|Bacteria,4NH34@976|Bacteroidetes,47MR1@768503|Cytophagia	976|Bacteroidetes	G	PFAM M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
TLS3_k127_7508523_3	929556.Solca_1857	5.298e-55	200.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,1IQV2@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family UPF0029, Impact, N-terminal	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
TLS3_k127_7508523_10	153721.MYP_1302	3.75e-05	54.0	COG2856@1|root,COG2856@2|Bacteria,4PKA4@976|Bacteroidetes,47S6I@768503|Cytophagia	976|Bacteroidetes	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7508523_8	1189620.AJXL01000195_gene3141	1.432e-34	135.0	COG1943@1|root,COG1943@2|Bacteria,4NQK5@976|Bacteroidetes,1I0TW@117743|Flavobacteriia,2P09J@237|Flavobacterium	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
TLS3_k127_7508523_5	745718.JADT01000013_gene1377	1.507e-37	142.0	COG1943@1|root,COG1943@2|Bacteria,4NQK5@976|Bacteroidetes,1I0TW@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
TLS3_k127_7508523_2	1341181.FLJC2902T_22700	9.985e-81	307.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NSSE@237|Flavobacterium	976|Bacteroidetes	O	gliding motility-associated C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
TLS3_k127_7508523_6	755732.Fluta_4029	6.286e-37	163.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_7508523_0	1453500.AT05_07450	0.0	1011.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1HWKZ@117743|Flavobacteriia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
TLS3_k127_7508523_9	1121897.AUGO01000005_gene47	1.76e-15	80.0	2ENN4@1|root,30R4Y@2|Bacteria,4PDD2@976|Bacteroidetes,1IDVM@117743|Flavobacteriia,2NZBK@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7508523_7	1237149.C900_03606	1.869e-35	135.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,47JS7@768503|Cytophagia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
TLS3_k127_7530219_1	1313301.AUGC01000004_gene2420	4.842e-102	337.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes	976|Bacteroidetes	S	of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
TLS3_k127_7530219_2	471870.BACINT_04334	1.557e-63	221.0	COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,2FS26@200643|Bacteroidia,4AQQT@815|Bacteroidaceae	976|Bacteroidetes	T	Psort location Cytoplasmic, score 8.96	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
TLS3_k127_7530219_0	762984.HMPREF9445_00706	4.853e-263	826.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,2FKZZ@200643|Bacteroidia,4AKM9@815|Bacteroidaceae	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
TLS3_k127_7530219_3	1123248.KB893320_gene3893	6.983e-51	186.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,1IXCE@117747|Sphingobacteriia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
TLS3_k127_7530300_3	468059.AUHA01000002_gene1011	2.277e-103	341.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1IQD3@117747|Sphingobacteriia	976|Bacteroidetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_7530300_2	1408433.JHXV01000008_gene143	3.102e-109	367.0	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,1HXD8@117743|Flavobacteriia,2PBCW@246874|Cryomorphaceae	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_7530300_1	1150600.ADIARSV_1616	2.999e-123	404.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,1IP2F@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
TLS3_k127_7530300_0	714943.Mucpa_6106	3.386e-164	522.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1IPXJ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TLS3_k127_7530300_4	1121904.ARBP01000007_gene2905	9.328e-74	250.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,47JXB@768503|Cytophagia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TLS3_k127_7545309_0	1408433.JHXV01000010_gene533	1.319e-107	355.0	COG1249@1|root,COG1249@2|Bacteria,4NJ2P@976|Bacteroidetes,1IGB0@117743|Flavobacteriia,2PBK6@246874|Cryomorphaceae	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_7545309_1	313606.M23134_07077	4.591e-95	331.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,47MII@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_7545309_2	761193.Runsl_2215	7.164e-30	120.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,47KCE@768503|Cytophagia	976|Bacteroidetes	T	PFAM response regulator receiver	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_7553433_0	1250232.JQNJ01000001_gene2119	2.884e-92	308.0	COG2267@1|root,COG2267@2|Bacteria,4PKRM@976|Bacteroidetes,1IJDT@117743|Flavobacteriia	976|Bacteroidetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
TLS3_k127_7553433_2	574376.BAMA_14970	1.74e-06	51.0	COG0604@1|root,COG0604@2|Bacteria,1TSWF@1239|Firmicutes,4HANV@91061|Bacilli,1ZPZP@1386|Bacillus	91061|Bacilli	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
TLS3_k127_7553433_1	693661.Arcve_0646	4.2e-34	135.0	arCOG06733@1|root,arCOG06733@2157|Archaea,2Y62E@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7559967_1	869213.JCM21142_114580	2.124e-54	196.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,47KM0@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
TLS3_k127_7559967_0	1349822.NSB1T_04955	4.509e-75	261.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,2FM2B@200643|Bacteroidia,22X69@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
TLS3_k127_7562971_14	485918.Cpin_0502	3.184e-23	104.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1IT51@117747|Sphingobacteriia	976|Bacteroidetes	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_7562971_12	755732.Fluta_3196	5.654e-35	138.0	2EDGF@1|root,337CN@2|Bacteria,4NXB6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7562971_23	269798.CHU_2011	5.233e-08	59.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
TLS3_k127_7562971_3	1267211.KI669560_gene2525	3.411e-165	531.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,1IQ1N@117747|Sphingobacteriia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
TLS3_k127_7562971_6	471854.Dfer_5317	1.357e-119	397.0	COG0642@1|root,COG2205@2|Bacteria,4NG0Y@976|Bacteroidetes,47JUV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
TLS3_k127_7562971_5	755732.Fluta_3200	1.233e-137	446.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,1HY0Y@117743|Flavobacteriia,2PBK1@246874|Cryomorphaceae	976|Bacteroidetes	T	Bacterial regulatory proteins, crp family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
TLS3_k127_7562971_17	1127692.HMPREF9075_00193	8.083e-21	103.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1HYE4@117743|Flavobacteriia,1EQQP@1016|Capnocytophaga	976|Bacteroidetes	T	Psort location Cytoplasmic, score 9.97	uspF	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_7562971_20	980584.AFPB01000068_gene1377	8.355e-14	81.0	COG0589@1|root,COG0589@2|Bacteria,4NHXF@976|Bacteroidetes,1HY7W@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_7562971_15	929556.Solca_1475	1.978e-21	98.0	COG2259@1|root,COG2259@2|Bacteria,4NVWM@976|Bacteroidetes,1IZEX@117747|Sphingobacteriia	976|Bacteroidetes	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
TLS3_k127_7562971_18	929562.Emtol_0844	9.888e-21	96.0	2AXFQ@1|root,31PF8@2|Bacteria,4NQN3@976|Bacteroidetes,47SZR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7562971_9	743722.Sph21_3592	4.251e-43	158.0	COG0526@1|root,COG0526@2|Bacteria,4PKQI@976|Bacteroidetes,1ITPA@117747|Sphingobacteriia	976|Bacteroidetes	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
TLS3_k127_7562971_11	1086011.HJ01_00039	3.541e-35	137.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,1I4FW@117743|Flavobacteriia,2NX6I@237|Flavobacterium	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS3_k127_7562971_13	1121895.Q765_19690	3.095e-25	111.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,1I34F@117743|Flavobacteriia,2NWHP@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
TLS3_k127_7562971_22	1121288.AULL01000012_gene321	1.147e-11	67.0	COG0607@1|root,COG0607@2|Bacteria,4NXGV@976|Bacteroidetes,1IGJ5@117743|Flavobacteriia,3ZSX3@59732|Chryseobacterium	976|Bacteroidetes	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7562971_10	886377.Murru_2637	3.432e-40	154.0	2E3RQ@1|root,32YPC@2|Bacteria,4NRGB@976|Bacteroidetes,1I4GF@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7562971_4	1279009.ADICEAN_00457	5.991e-165	530.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,47K3T@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
TLS3_k127_7562971_2	929556.Solca_0125	4.665e-166	531.0	COG0076@1|root,COG0076@2|Bacteria,4NGRW@976|Bacteroidetes,1IQ1M@117747|Sphingobacteriia	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
TLS3_k127_7562971_8	1168034.FH5T_09735	1.212e-58	212.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes	976|Bacteroidetes	S	cytochrome c biogenesis protein	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
TLS3_k127_7562971_16	1237149.C900_03362	6.441e-21	97.0	COG3198@1|root,COG3198@2|Bacteria,4PPZ3@976|Bacteroidetes,47RV1@768503|Cytophagia	976|Bacteroidetes	S	FixH	ccoH	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
TLS3_k127_7562971_1	929556.Solca_1394	1.353e-190	605.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1IP29@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
TLS3_k127_7562971_7	700598.Niako_1943	2.986e-82	287.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1IRZW@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
TLS3_k127_7562971_21	929556.Solca_1392	4.931e-12	67.0	COG2010@1|root,COG2010@2|Bacteria,4PJ6S@976|Bacteroidetes,1IZP1@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7562971_0	1123248.KB893386_gene1898	0.0	1177.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1IP6D@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
TLS3_k127_7562971_19	1048983.EL17_01585	2.372e-14	74.0	COG3197@1|root,COG3197@2|Bacteria,4NUR7@976|Bacteroidetes,47SPA@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM cytochrome oxidase maturation protein, cbb3-type	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
TLS3_k127_7562971_24	1158146.KB907121_gene959	3.056e-06	49.0	COG2608@1|root,COG2608@2|Bacteria,1N81B@1224|Proteobacteria,1SD0H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
TLS3_k127_7579518_8	714943.Mucpa_5862	2.511e-39	148.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1IPM2@117747|Sphingobacteriia	976|Bacteroidetes	G	COG0738 Fucose permease	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
TLS3_k127_7579518_3	1346330.M472_19480	1.301e-118	390.0	COG1092@1|root,COG1092@2|Bacteria,4NGJX@976|Bacteroidetes,1IRFX@117747|Sphingobacteriia	976|Bacteroidetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
TLS3_k127_7579518_9	330214.NIDE1683	9.506e-28	126.0	COG0652@1|root,COG0652@2|Bacteria,3J18H@40117|Nitrospirae	40117|Nitrospirae	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
TLS3_k127_7579518_4	755732.Fluta_1284	1.212e-93	331.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
TLS3_k127_7579518_6	1131812.JQMS01000001_gene455	2.017e-61	216.0	COG2318@1|root,COG2318@2|Bacteria,4NNQI@976|Bacteroidetes,1I28A@117743|Flavobacteriia,2NTF8@237|Flavobacterium	976|Bacteroidetes	S	DinB superfamily	yfiT	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_7579518_5	1134474.O59_002954	8.029e-64	224.0	COG3145@1|root,COG3145@2|Bacteria,1RGXU@1224|Proteobacteria,1S6DD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Alkylated DNA repair protein	alkB	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
TLS3_k127_7579518_1	1185876.BN8_00138	8.276e-159	511.0	COG0477@1|root,COG2814@2|Bacteria,4NESW@976|Bacteroidetes,47JIH@768503|Cytophagia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_7579518_7	269798.CHU_0700	7.38e-45	168.0	COG2010@1|root,COG2010@2|Bacteria,4NQN1@976|Bacteroidetes,47XSN@768503|Cytophagia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
TLS3_k127_7579518_2	761193.Runsl_5035	2.449e-152	493.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47M80@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
TLS3_k127_7579518_0	1408473.JHXO01000009_gene3365	8.633e-223	700.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,2FKZ6@200643|Bacteroidia	976|Bacteroidetes	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
TLS3_k127_7579518_10	525373.HMPREF0766_11441	6.419e-14	75.0	COG3027@1|root,COG3027@2|Bacteria,4NSA5@976|Bacteroidetes,1ITBU@117747|Sphingobacteriia	976|Bacteroidetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
TLS3_k127_7598638_1	1313301.AUGC01000011_gene1173	3.791e-80	273.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
TLS3_k127_7598638_0	762903.Pedsa_2259	3.223e-196	619.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,1IPB1@117747|Sphingobacteriia	976|Bacteroidetes	J	tRNA nucleotidyltransferase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
TLS3_k127_7612751_1	1346330.M472_18510	5.689e-34	135.0	COG2912@1|root,COG2912@2|Bacteria,4NF8R@976|Bacteroidetes,1IP0V@117747|Sphingobacteriia	976|Bacteroidetes	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
TLS3_k127_7612751_0	504472.Slin_4218	1.666e-71	262.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47NXA@768503|Cytophagia	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Cleaved_Adhesin,PKD,Peptidase_M43,fn3
TLS3_k127_7626896_0	269798.CHU_2794	3.442e-84	293.0	COG0476@1|root,COG0778@1|root,COG0476@2|Bacteria,COG0778@2|Bacteria,4NHWN@976|Bacteroidetes,47JCT@768503|Cytophagia	976|Bacteroidetes	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
TLS3_k127_7626896_1	391596.PBAL39_24755	1.559e-66	232.0	28IFK@1|root,2Z8HB@2|Bacteria,4NH1P@976|Bacteroidetes,1IS1Z@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7651546_0	1408433.JHXV01000004_gene3388	6.959e-61	224.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,1I54C@117743|Flavobacteriia,2PAIC@246874|Cryomorphaceae	976|Bacteroidetes	Q	PFAM FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS3_k127_7651546_1	1408433.JHXV01000009_gene1339	4.154e-14	82.0	COG3011@1|root,COG3011@2|Bacteria,4NQY0@976|Bacteroidetes,1IIAF@117743|Flavobacteriia	976|Bacteroidetes	S	Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
TLS3_k127_765950_6	1453498.LG45_14535	7.952e-06	49.0	2EC34@1|root,33623@2|Bacteria,4NVW7@976|Bacteroidetes,1I737@117743|Flavobacteriia,2NWAU@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
TLS3_k127_765950_4	1131812.JQMS01000001_gene2358	3.404e-15	80.0	2EBJZ@1|root,335KD@2|Bacteria,4NWP2@976|Bacteroidetes,1IBI0@117743|Flavobacteriia,2NWNQ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_765950_1	269798.CHU_2927	3.394e-96	326.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,47KDN@768503|Cytophagia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS3_k127_765950_0	700598.Niako_1885	1.926e-96	323.0	COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,1IPKD@117747|Sphingobacteriia	976|Bacteroidetes	Q	COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
TLS3_k127_765950_2	1121890.AUDO01000007_gene2439	6.373e-86	290.0	COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,1HXP0@117743|Flavobacteriia,2NT00@237|Flavobacterium	976|Bacteroidetes	Q	Organic solvent ABC transporter ATP-binding protein	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
TLS3_k127_765950_3	1121890.AUDO01000007_gene2440	1.977e-58	210.0	COG1463@1|root,COG1463@2|Bacteria,4NNXB@976|Bacteroidetes,1IIYQ@117743|Flavobacteriia,2P0H6@237|Flavobacterium	976|Bacteroidetes	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
TLS3_k127_765950_5	159450.NH14_19265	2.143e-07	64.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,2VIKY@28216|Betaproteobacteria,1K3FN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	AsmA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
TLS3_k127_7687425_0	153721.MYP_3422	1.302e-223	711.0	COG1858@1|root,COG1858@2|Bacteria,4NE50@976|Bacteroidetes,47KXQ@768503|Cytophagia	976|Bacteroidetes	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
TLS3_k127_7704151_0	1434325.AZQN01000006_gene3279	2.73e-174	555.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,47KZC@768503|Cytophagia	976|Bacteroidetes	S	PFAM Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
TLS3_k127_7704151_1	755732.Fluta_2239	8.567e-21	94.0	COG1011@1|root,COG1011@2|Bacteria,4NM66@976|Bacteroidetes,1I188@117743|Flavobacteriia,2PAUK@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	yjjG	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
TLS3_k127_7710734_1	869213.JCM21142_3939	7.336e-45	177.0	COG1193@1|root,COG1193@2|Bacteria,4NNNV@976|Bacteroidetes	976|Bacteroidetes	L	DNA mismatch repair protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2027,Smr
TLS3_k127_7710734_0	1124780.ANNU01000005_gene2425	2.745e-76	259.0	COG0399@1|root,COG0399@2|Bacteria,4NFQ8@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_7720589_6	1408473.JHXO01000006_gene1410	1.715e-59	208.0	COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,2FNJ6@200643|Bacteroidia	976|Bacteroidetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
TLS3_k127_7720589_5	929556.Solca_0419	4.212e-71	242.0	COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,1IRUT@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
TLS3_k127_7720589_2	1336803.PHEL49_1305	1.24e-113	370.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,1HZJ6@117743|Flavobacteriia,3VVBP@52959|Polaribacter	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
TLS3_k127_7720589_8	984262.SGRA_2308	2.23e-44	166.0	COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,1IS1J@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
TLS3_k127_7720589_7	269798.CHU_3170	6.758e-46	168.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,47PSQ@768503|Cytophagia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
TLS3_k127_7720589_1	762903.Pedsa_2264	0.0	2080.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1INW0@117747|Sphingobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
TLS3_k127_7720589_0	929556.Solca_0424	0.0	2191.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,1IP5J@117747|Sphingobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
TLS3_k127_7720589_9	1313421.JHBV01000011_gene4054	6.542e-36	150.0	2D45Q@1|root,32TGB@2|Bacteria,4NTFZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7720589_4	1408473.JHXO01000011_gene3066	2.128e-86	290.0	COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,2FPPX@200643|Bacteroidia	976|Bacteroidetes	Q	FAH family	fahA	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
TLS3_k127_7720589_3	755732.Fluta_4031	1.711e-94	317.0	COG0579@1|root,COG0579@2|Bacteria,4NE0B@976|Bacteroidetes,1HZQJ@117743|Flavobacteriia,2PACG@246874|Cryomorphaceae	976|Bacteroidetes	S	FAD dependent oxidoreductase	lhgO	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
TLS3_k127_7733687_1	543913.D521_1283	5.89e-147	483.0	COG1479@1|root,COG3472@1|root,COG1479@2|Bacteria,COG3472@2|Bacteria,1PG72@1224|Proteobacteria,2WAVX@28216|Betaproteobacteria,1KR2F@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
TLS3_k127_7733687_0	1408433.JHXV01000025_gene4017	0.0	1427.0	COG0610@1|root,COG0610@2|Bacteria,4NFJ8@976|Bacteroidetes,1HXHQ@117743|Flavobacteriia,2PA4Z@246874|Cryomorphaceae	976|Bacteroidetes	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
TLS3_k127_7735354_1	1287488.HMPREF0671_09960	2.222e-19	99.0	COG3712@1|root,COG3712@2|Bacteria,4NKN5@976|Bacteroidetes,2FQIS@200643|Bacteroidia	976|Bacteroidetes	PT	Sigma factor regulatory protein, FecR PupR family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
TLS3_k127_7735354_0	471854.Dfer_2829	1.595e-48	180.0	COG1595@1|root,COG1595@2|Bacteria,4NNBY@976|Bacteroidetes,47PH5@768503|Cytophagia	976|Bacteroidetes	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_7755728_25	1046627.BZARG_1092	5.569e-10	61.0	COG0744@1|root,COG0744@2|Bacteria,4NF90@976|Bacteroidetes,1HXMN@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
TLS3_k127_7755728_12	1123248.KB893340_gene2662	3.475e-75	266.0	COG1680@1|root,COG1680@2|Bacteria,4NFMQ@976|Bacteroidetes,1IQ1K@117747|Sphingobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_7755728_10	926562.Oweho_1586	8.346e-92	308.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,1HX1M@117743|Flavobacteriia,2PAR7@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
TLS3_k127_7755728_2	468059.AUHA01000002_gene32	1.902e-140	465.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1IR8V@117747|Sphingobacteriia	976|Bacteroidetes	N	transport system involved in gliding motility, auxiliary component	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
TLS3_k127_7755728_15	755732.Fluta_3942	3.043e-37	148.0	COG2197@1|root,COG2197@2|Bacteria,4NNVV@976|Bacteroidetes,1ICPE@117743|Flavobacteriia,2PBHR@246874|Cryomorphaceae	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
TLS3_k127_7755728_9	1237149.C900_04769	1.568e-94	319.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,47KGX@768503|Cytophagia	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
TLS3_k127_7755728_13	1305737.JAFX01000001_gene3064	2.183e-57	203.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,47PQ3@768503|Cytophagia	976|Bacteroidetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
TLS3_k127_7755728_21	391598.FBBAL38_05855	3.634e-17	98.0	COG4409@1|root,COG4409@2|Bacteria,4PM7K@976|Bacteroidetes,1IJKJ@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 18 family	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10,fn3
TLS3_k127_7755728_24	1341155.FSS13T_05700	2.187e-12	82.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,1HYZP@117743|Flavobacteriia,2P055@237|Flavobacterium	976|Bacteroidetes	E	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	CUB,MAM,PA,TSP_3,fn3
TLS3_k127_7755728_5	391587.KAOT1_08543	7.121e-109	359.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1HXU4@117743|Flavobacteriia	976|Bacteroidetes	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS
TLS3_k127_7755728_8	929556.Solca_1342	3.105e-104	344.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,1IPA8@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
TLS3_k127_7755728_1	1237149.C900_00764	1.073e-154	499.0	COG0761@1|root,COG0761@2|Bacteria,4NDUX@976|Bacteroidetes,47M0Y@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
TLS3_k127_7755728_4	1122621.ATZA01000041_gene2680	9.721e-116	380.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1IP1B@117747|Sphingobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
TLS3_k127_7755728_14	1202532.FF52_08987	7.593e-54	192.0	COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,1I20S@117743|Flavobacteriia,2NVWI@237|Flavobacterium	976|Bacteroidetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
TLS3_k127_7755728_17	1450525.JATV01000013_gene2841	7.32e-35	134.0	2BFRA@1|root,329K3@2|Bacteria,4NR20@976|Bacteroidetes,1I5JZ@117743|Flavobacteriia,2P0CA@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7755728_22	1450525.JATV01000013_gene2841	4.927e-15	75.0	2BFRA@1|root,329K3@2|Bacteria,4NR20@976|Bacteroidetes,1I5JZ@117743|Flavobacteriia,2P0CA@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7755728_23	1123276.KB893274_gene2457	2.068e-12	68.0	COG3547@1|root,COG3547@2|Bacteria,4NKDC@976|Bacteroidetes,47NU4@768503|Cytophagia	976|Bacteroidetes	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
TLS3_k127_7755728_18	411154.GFO_2569	2.889e-34	140.0	2DQP5@1|root,337VV@2|Bacteria,4P3M5@976|Bacteroidetes,1I922@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7755728_7	1242864.D187_000513	8.137e-107	352.0	COG4221@1|root,COG4221@2|Bacteria,1QTXD@1224|Proteobacteria	1224|Proteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	MA20_36825	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_7755728_11	1120965.AUBV01000005_gene1814	2.035e-75	260.0	COG0009@1|root,COG0009@2|Bacteria,4NDZR@976|Bacteroidetes,47KWK@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
TLS3_k127_7755728_19	1120968.AUBX01000012_gene2669	7.17e-32	133.0	2ATWF@1|root,31JFP@2|Bacteria,4NQPB@976|Bacteroidetes,47SD4@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7755728_16	388413.ALPR1_09023	6.508e-35	142.0	2C7HJ@1|root,31BFZ@2|Bacteria,4NRGQ@976|Bacteroidetes,47WSM@768503|Cytophagia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_7755728_6	1450525.JATV01000004_gene189	3.614e-108	365.0	COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,1HWRE@117743|Flavobacteriia,2NSI2@237|Flavobacterium	976|Bacteroidetes	MU	membrane	-	-	-	ko:K18139,ko:K18300	ko01501,ko02024,map01501,map02024	M00641,M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
TLS3_k127_7755728_0	991.IW20_02945	0.0	1680.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,2NTDQ@237|Flavobacterium	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
TLS3_k127_7755728_3	1202532.FF52_11466	1.439e-134	441.0	COG0845@1|root,COG0845@2|Bacteria,4NIDC@976|Bacteroidetes,1HZ9U@117743|Flavobacteriia,2P02F@237|Flavobacterium	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
TLS3_k127_7755728_20	1121904.ARBP01000013_gene309	3.138e-20	96.0	COG1226@1|root,32Y28@2|Bacteria	2|Bacteria	P	Ion transport 2 domain protein	RB9536	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
TLS3_k127_7756323_13	1349785.BAUG01000046_gene2295	4.533e-16	79.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,1HXD5@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
TLS3_k127_7756323_6	1408433.JHXV01000006_gene2698	2.16e-105	348.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,1HXJZ@117743|Flavobacteriia,2PAE7@246874|Cryomorphaceae	976|Bacteroidetes	G	Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
TLS3_k127_7756323_12	468059.AUHA01000002_gene659	3.775e-22	110.0	2A79D@1|root,30W5Z@2|Bacteria,4NN88@976|Bacteroidetes,1IRXG@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
TLS3_k127_7756323_8	1349785.BAUG01000009_gene740	3.292e-60	226.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1HWXT@117743|Flavobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7756323_14	1453500.AT05_01730	3.708e-12	78.0	2CA1R@1|root,3391I@2|Bacteria,4NXBJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
TLS3_k127_7756323_0	929556.Solca_2982	4.84e-322	994.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,1IPCI@117747|Sphingobacteriia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
TLS3_k127_7756323_10	1121373.KB903644_gene3389	2.26e-26	120.0	COG0526@1|root,COG0526@2|Bacteria,4PIJM@976|Bacteroidetes	976|Bacteroidetes	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7756323_11	1227739.Hsw_0258	7.25e-25	113.0	29TMV@1|root,30EVG@2|Bacteria,4NNPM@976|Bacteroidetes,47RB5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7756323_2	926549.KI421517_gene2402	3.146e-173	570.0	COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,47XXA@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_7756323_3	385682.AFSL01000019_gene2271	1.068e-134	451.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,2FN3A@200643|Bacteroidia,3XJ5F@558415|Marinilabiliaceae	976|Bacteroidetes	U	YidC periplasmic domain	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
TLS3_k127_7756323_4	649349.Lbys_1960	1.504e-133	439.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,47KI1@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
TLS3_k127_7756323_5	1122226.AUHX01000015_gene1344	3.463e-130	429.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1HY7Q@117743|Flavobacteriia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_7756323_1	1408433.JHXV01000034_gene11	1.336e-173	560.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1HXGH@117743|Flavobacteriia,2PA9N@246874|Cryomorphaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TLS3_k127_7756323_7	755732.Fluta_2549	2.062e-97	329.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1HZRC@117743|Flavobacteriia,2PANF@246874|Cryomorphaceae	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_7756323_9	362418.IW19_16025	3.439e-46	183.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1HYJD@117743|Flavobacteriia,2NS7F@237|Flavobacterium	976|Bacteroidetes	S	Peptidase C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
TLS3_k127_7758151_0	1121904.ARBP01000005_gene4745	7.621e-63	227.0	2E074@1|root,32VV1@2|Bacteria,4NTTK@976|Bacteroidetes,47UPG@768503|Cytophagia	976|Bacteroidetes	S	Bacterial toxin 23	-	-	-	-	-	-	-	-	-	-	-	-	Ntox23
TLS3_k127_7758151_1	1123276.KB893311_gene3142	8.563e-33	139.0	2DN4I@1|root,32VGS@2|Bacteria,4NNY4@976|Bacteroidetes,47PHY@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
TLS3_k127_7758151_2	1121481.AUAS01000014_gene2431	5.925e-14	72.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47JN3@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_7781076_2	1121904.ARBP01000005_gene4739	3.484e-58	220.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,47K9X@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
TLS3_k127_7781076_1	755732.Fluta_1216	9.35e-83	301.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2PBDM@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
TLS3_k127_7781076_0	714943.Mucpa_2689	3.76e-135	437.0	COG0330@1|root,COG0330@2|Bacteria,4NEP5@976|Bacteroidetes,1IQTZ@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TLS3_k127_7787724_15	755732.Fluta_1299	5.155e-11	66.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1HXG2@117743|Flavobacteriia,2PAGS@246874|Cryomorphaceae	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase N-terminus	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
TLS3_k127_7787724_16	888059.HMPREF9071_1857	1.723e-06	55.0	2C8TJ@1|root,32RMV@2|Bacteria,4NSAA@976|Bacteroidetes,1I54A@117743|Flavobacteriia,1ES0T@1016|Capnocytophaga	976|Bacteroidetes	S	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
TLS3_k127_7787724_10	880073.Calab_2546	5.46e-43	178.0	COG2372@1|root,COG4733@1|root,COG2372@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K07156	-	-	-	-	ko00000,ko02000	9.B.62.2	-	-	Big_5,DUF4082,SASA,fn3
TLS3_k127_7787724_0	580332.Slit_2861	0.0	1366.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,44V7J@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
TLS3_k127_7787724_11	755732.Fluta_1974	9.549e-43	170.0	COG2849@1|root,COG2849@2|Bacteria,4PG65@976|Bacteroidetes,1IMR5@117743|Flavobacteriia,2PBMX@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_7787724_1	714943.Mucpa_3052	4.334e-177	561.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1IPCZ@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
TLS3_k127_7787724_3	616991.JPOO01000001_gene3889	1.941e-161	516.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HX7B@117743|Flavobacteriia,23G88@178469|Arenibacter	976|Bacteroidetes	I	Thiolase, C-terminal domain	phbA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
TLS3_k127_7787724_5	509635.N824_14215	4.57e-116	382.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1IQE6@117747|Sphingobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
TLS3_k127_7787724_13	755732.Fluta_3212	1.871e-25	124.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Laminin_G_3,PKD
TLS3_k127_7787724_12	1121889.AUDM01000008_gene766	2.365e-32	146.0	COG1345@1|root,COG3291@1|root,COG1345@2|Bacteria,COG3291@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,2NSFX@237|Flavobacterium	976|Bacteroidetes	N	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CUB,fn3
TLS3_k127_7787724_9	997884.HMPREF1068_00250	3.399e-56	202.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,2FP46@200643|Bacteroidia,4AMVS@815|Bacteroidaceae	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
TLS3_k127_7787724_4	1121373.KB903663_gene1074	3.846e-140	485.0	COG0457@1|root,COG2849@1|root,COG0457@2|Bacteria,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47N8G@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TPR_1,TPR_16,TPR_8
TLS3_k127_7787724_8	153721.MYP_3157	1.718e-80	292.0	COG1305@1|root,COG1305@2|Bacteria,4NI6P@976|Bacteroidetes,47KR7@768503|Cytophagia	976|Bacteroidetes	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
TLS3_k127_7787724_7	153721.MYP_3158	2.534e-99	348.0	28HFP@1|root,2Z7RP@2|Bacteria,4NHVI@976|Bacteroidetes,47NP6@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857
TLS3_k127_7787724_14	1408433.JHXV01000031_gene3210	2.145e-21	106.0	COG0457@1|root,COG0457@2|Bacteria,4PIM4@976|Bacteroidetes,1IMKJ@117743|Flavobacteriia,2PC1A@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
TLS3_k127_7787724_6	1406840.Q763_00740	1.211e-115	376.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1HX61@117743|Flavobacteriia,2NU9K@237|Flavobacterium	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
TLS3_k127_7787724_2	1122176.KB903568_gene3468	2.112e-166	554.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,1IPK5@117747|Sphingobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_7805437_2	926562.Oweho_2395	7.182e-46	171.0	COG1595@1|root,COG1595@2|Bacteria,4NKHT@976|Bacteroidetes,1IG88@117743|Flavobacteriia,2PB14@246874|Cryomorphaceae	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_7805437_1	929556.Solca_2327	2.083e-131	426.0	COG0777@1|root,COG0777@2|Bacteria,4NFMH@976|Bacteroidetes,1IPMT@117747|Sphingobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
TLS3_k127_7805437_0	1313301.AUGC01000010_gene956	1.561e-185	583.0	COG1830@1|root,COG1830@2|Bacteria,4NEUM@976|Bacteroidetes	976|Bacteroidetes	G	Aldolase	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
TLS3_k127_781818_1	1453498.LG45_12115	4.806e-66	237.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLH,fn3
TLS3_k127_781818_2	1121373.KB903654_gene1710	7.621e-14	85.0	COG3291@1|root,COG3693@1|root,COG3979@1|root,COG3291@2|Bacteria,COG3693@2|Bacteria,COG3979@2|Bacteria	2|Bacteria	S	chitin catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_3,CHU_C,Glyco_hydro_9,PKD,Ricin_B_lectin
TLS3_k127_781818_0	1123057.P872_04205	1.853e-97	327.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,47KTA@768503|Cytophagia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
TLS3_k127_7829568_10	926562.Oweho_2182	7.718e-25	106.0	COG0721@1|root,COG0721@2|Bacteria,4NV0A@976|Bacteroidetes,1IBR4@117743|Flavobacteriia,2PB5V@246874|Cryomorphaceae	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
TLS3_k127_7829568_7	313606.M23134_05531	2.176e-42	166.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,47JI7@768503|Cytophagia	976|Bacteroidetes	I	TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TLS3_k127_7829568_3	1122176.KB903541_gene252	1.286e-68	243.0	COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,1IRHE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Bacterial lipid A biosynthesis acyltransferase	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
TLS3_k127_7829568_2	643867.Ftrac_1237	1.054e-133	454.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47K1N@768503|Cytophagia	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
TLS3_k127_7829568_4	1408433.JHXV01000015_gene1756	1.006e-67	241.0	COG0226@1|root,COG0226@2|Bacteria,4PKGM@976|Bacteroidetes,1IK6K@117743|Flavobacteriia,2PC6S@246874|Cryomorphaceae	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_7829568_9	714943.Mucpa_4104	8.695e-30	141.0	COG2373@1|root,COG3210@1|root,COG5184@1|root,COG2373@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria,4NKG5@976|Bacteroidetes	976|Bacteroidetes	U	Psort location Extracellular, score 9.64	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SASA
TLS3_k127_7829568_0	1089547.KB913013_gene3820	8.322e-200	704.0	COG2373@1|root,COG3291@1|root,COG4932@1|root,COG2373@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,4NM7C@976|Bacteroidetes,47RKX@768503|Cytophagia	976|Bacteroidetes	N	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHU_C
TLS3_k127_7829568_11	525257.HMPREF0204_10563	3.627e-12	83.0	COG3291@1|root,COG3291@2|Bacteria,4NU74@976|Bacteroidetes,1I4JY@117743|Flavobacteriia,3ZT65@59732|Chryseobacterium	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7829568_1	1270196.JCKI01000002_gene38	6.719e-178	576.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
TLS3_k127_7829568_5	742727.HMPREF9447_05077	1.825e-64	228.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,2FNMJ@200643|Bacteroidia,4AK5X@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
TLS3_k127_7829568_8	929556.Solca_4361	8.228e-35	146.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,1IS2B@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TLS3_k127_7829568_6	153721.MYP_243	1.145e-50	194.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
TLS3_k127_7855395_2	760192.Halhy_0958	1.359e-53	193.0	29E7I@1|root,3015I@2|Bacteria,4NNFG@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
TLS3_k127_7855395_0	929556.Solca_2258	1.336e-204	650.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,1IPNZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
TLS3_k127_7855395_6	760192.Halhy_0213	1.773e-31	136.0	COG3291@1|root,COG3291@2|Bacteria,4PN79@976|Bacteroidetes	976|Bacteroidetes	G	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_7855395_1	1408813.AYMG01000008_gene3837	5.915e-59	233.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1IPPI@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,Reg_prop,Y_Y_Y
TLS3_k127_7855395_3	1270196.JCKI01000003_gene1929	8.535e-51	189.0	COG3279@1|root,COG3279@2|Bacteria,4NEXZ@976|Bacteroidetes	976|Bacteroidetes	T	COG3279 Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_7855395_5	1229487.AMYW01000006_gene622	1.884e-33	132.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I2UG@117743|Flavobacteriia,2NWNB@237|Flavobacterium	976|Bacteroidetes	L	single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
TLS3_k127_7855395_4	1123248.KB893386_gene1826	1.97e-35	138.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1ITMD@117747|Sphingobacteriia	976|Bacteroidetes	L	Single-strand binding protein family	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
TLS3_k127_7855395_7	391598.FBBAL38_11499	9.422e-27	118.0	COG5295@1|root,COG5295@2|Bacteria,4NTMP@976|Bacteroidetes,1I4NQ@117743|Flavobacteriia	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Fib_succ_major
TLS3_k127_7868008_1	1122226.AUHX01000005_gene2324	4.578e-95	319.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1HWZJ@117743|Flavobacteriia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
TLS3_k127_7868008_0	755732.Fluta_0646	1.342e-207	652.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,1HXRF@117743|Flavobacteriia,2PAK2@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
TLS3_k127_7868008_3	880071.Fleli_3989	1.512e-05	55.0	COG1361@1|root,COG3291@1|root,COG4886@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,CBM_3,CHU_C,DUF285,Glyco_hydro_9,PKD,Peptidase_M43,VCBS
TLS3_k127_7868008_2	760192.Halhy_3381	1.123e-09	68.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.4,5.2.1.8	ko:K01179,ko:K03768,ko:K08738	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000,ko03110	3.D.4.6	GH5,GH9	-	CHU_C,PKD,PQQ,PQQ_2,SprB,fn3
TLS3_k127_7877335_2	1185876.BN8_04086	4.062e-13	81.0	COG4447@1|root,COG4447@2|Bacteria,4NTT3@976|Bacteroidetes,47T1M@768503|Cytophagia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7877335_0	926549.KI421517_gene926	1.124e-185	594.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,47K3J@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
TLS3_k127_7877335_1	643867.Ftrac_2948	2.534e-26	109.0	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,47R4H@768503|Cytophagia	976|Bacteroidetes	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
TLS3_k127_7878199_0	1250278.JQNQ01000001_gene2847	3.48e-136	439.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,1HX6U@117743|Flavobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
TLS3_k127_7878199_1	1121887.AUDK01000029_gene2544	4.494e-64	228.0	COG2859@1|root,COG2859@2|Bacteria,4NI76@976|Bacteroidetes,1HZJF@117743|Flavobacteriia,2NTST@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
TLS3_k127_7878199_5	1408813.AYMG01000023_gene2022	3.651e-16	78.0	2AC5I@1|root,311PY@2|Bacteria,4PGIV@976|Bacteroidetes,1ITTN@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4295
TLS3_k127_7878199_2	1286632.P278_04220	1.822e-28	114.0	COG0267@1|root,COG0267@2|Bacteria,4NURM@976|Bacteroidetes,1I55D@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
TLS3_k127_7878199_3	926562.Oweho_1271	1.536e-27	113.0	COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,1I3YG@117743|Flavobacteriia,2PB6U@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
TLS3_k127_7878199_4	236814.IX39_04315	9.309e-25	108.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,1HX8D@117743|Flavobacteriia,3ZR0P@59732|Chryseobacterium	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
TLS3_k127_7892605_1	1408813.AYMG01000010_gene292	7.509e-169	544.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,4NDX5@976|Bacteroidetes,1IPE5@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase	dpx	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,HHH_8,PHP
TLS3_k127_7892605_0	1250006.JHZZ01000001_gene827	6.49e-182	580.0	COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,1IJBB@117743|Flavobacteriia,3VWBU@52959|Polaribacter	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
TLS3_k127_7926032_1	1122605.KB893633_gene4279	3.875e-78	273.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,1IQ7X@117747|Sphingobacteriia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
TLS3_k127_7926032_0	755732.Fluta_1606	1.6e-161	520.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,1HXAE@117743|Flavobacteriia,2PA4J@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid	kmo	-	1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
TLS3_k127_7926032_3	269798.CHU_3612	2.212e-46	175.0	COG1285@1|root,COG1285@2|Bacteria,4NRHK@976|Bacteroidetes,47MUD@768503|Cytophagia	976|Bacteroidetes	S	PFAM MgtC SapB transporter	mgtC	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
TLS3_k127_7926032_2	927658.AJUM01000037_gene1873	1.795e-54	195.0	COG1595@1|root,COG1595@2|Bacteria,4NQ7S@976|Bacteroidetes,2FTDI@200643|Bacteroidia,3XK6J@558415|Marinilabiliaceae	976|Bacteroidetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_7935968_6	1469557.JSWF01000017_gene2356	1.531e-06	59.0	COG1835@1|root,COG1835@2|Bacteria,4NW1Q@976|Bacteroidetes	976|Bacteroidetes	I	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS3_k127_7935968_1	1286632.P278_00430	2.119e-161	525.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,1HXJR@117743|Flavobacteriia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
TLS3_k127_7935968_0	1408433.JHXV01000017_gene1578	9.263e-198	634.0	COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,1HWS6@117743|Flavobacteriia,2PAF1@246874|Cryomorphaceae	976|Bacteroidetes	GM	PFAM Polysaccharide biosynthesis protein	wbpM	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
TLS3_k127_7935968_4	1185876.BN8_01755	4.708e-25	109.0	2DF5F@1|root,330HX@2|Bacteria,4PPXU@976|Bacteroidetes,47X74@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7935968_5	1121904.ARBP01000012_gene1325	3.937e-07	58.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_7935968_2	714943.Mucpa_1297	2.759e-127	414.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1INM5@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
TLS3_k127_7935968_3	761193.Runsl_1849	1.175e-69	240.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,47KHN@768503|Cytophagia	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
TLS3_k127_7949785_4	762903.Pedsa_2886	2.306e-23	105.0	COG0775@1|root,COG0775@2|Bacteria,4NQVQ@976|Bacteroidetes,1IT1C@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnB	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
TLS3_k127_7949785_2	925409.KI911562_gene1491	8.933e-67	229.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1ISCG@117747|Sphingobacteriia	976|Bacteroidetes	H	6-pyruvoyl tetrahydrobiopterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
TLS3_k127_7949785_3	504487.JCM19302_3076	2.606e-26	112.0	COG0720@1|root,COG0720@2|Bacteria,4NNIS@976|Bacteroidetes,1I1ZF@117743|Flavobacteriia	976|Bacteroidetes	H	synthase	ygcM	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
TLS3_k127_7949785_0	929703.KE386491_gene1576	7.009e-109	356.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,47MMS@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
TLS3_k127_7949785_1	755732.Fluta_1284	8.034e-99	349.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
TLS3_k127_7949785_5	746697.Aeqsu_0515	0.0001171	48.0	COG4935@1|root,COG4935@2|Bacteria,4NF3C@976|Bacteroidetes,1HWT9@117743|Flavobacteriia	976|Bacteroidetes	O	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Omp28
TLS3_k127_795469_5	1408433.JHXV01000005_gene2290	1.453e-17	92.0	COG1729@1|root,COG1729@2|Bacteria,4PMDU@976|Bacteroidetes,1IKE6@117743|Flavobacteriia,2PB2R@246874|Cryomorphaceae	976|Bacteroidetes	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
TLS3_k127_795469_6	983548.Krodi_2423	2.452e-06	51.0	2EH3X@1|root,33AVW@2|Bacteria,4NYC0@976|Bacteroidetes,1I6GU@117743|Flavobacteriia,37FFQ@326319|Dokdonia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_795469_1	886379.AEWI01000047_gene3073	9.29e-62	222.0	29UMW@1|root,30FZE@2|Bacteria,4NP3W@976|Bacteroidetes,2G24N@200643|Bacteroidia,3XJR5@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_795469_3	927658.AJUM01000037_gene2416	6.556e-40	156.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,2FU3S@200643|Bacteroidia,3XK87@558415|Marinilabiliaceae	976|Bacteroidetes	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_795469_0	1538644.KO02_18920	3.4e-200	629.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,1INQM@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
TLS3_k127_795469_2	1121896.JMLU01000003_gene2194	3.765e-42	180.0	COG1357@1|root,COG3291@1|root,COG4935@1|root,COG1357@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZC@976|Bacteroidetes,1I0G4@117743|Flavobacteriia,2NT7Y@237|Flavobacterium	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CHU_C,He_PIG,fn3
TLS3_k127_795469_4	1356852.N008_20685	1.474e-38	168.0	COG1361@1|root,COG1372@1|root,COG2304@1|root,COG2911@1|root,COG3209@1|root,COG3468@1|root,COG1361@2|Bacteria,COG1372@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3468@2|Bacteria,4PKBQ@976|Bacteroidetes,47XXU@768503|Cytophagia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SdrD_B,SprB
TLS3_k127_8004553_4	1041826.FCOL_09620	1.153e-71	248.0	COG0300@1|root,COG0300@2|Bacteria,4NKNE@976|Bacteroidetes,1IMIN@117743|Flavobacteriia,2NTWH@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
TLS3_k127_8004553_0	468059.AUHA01000004_gene2361	0.0	1258.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,1IQP6@117747|Sphingobacteriia	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
TLS3_k127_8004553_10	402777.KB235898_gene5110	7.344e-06	53.0	COG1246@1|root,COG1246@2|Bacteria,1G5ND@1117|Cyanobacteria,1HAXA@1150|Oscillatoriales	1117|Cyanobacteria	E	Acetyltransferase (GNAT) family	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
TLS3_k127_8004553_3	1121899.Q764_08285	7.419e-84	282.0	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,1HY9T@117743|Flavobacteriia,2NT0A@237|Flavobacterium	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
TLS3_k127_8004553_6	1185876.BN8_00662	6.559e-52	197.0	29RVA@1|root,30CZB@2|Bacteria,4NNXY@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1207
TLS3_k127_8004553_1	1089547.KB913013_gene3911	2.065e-140	461.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,47KNW@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
TLS3_k127_8004553_2	929562.Emtol_2961	2.658e-119	392.0	COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,47K2G@768503|Cytophagia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
TLS3_k127_8004553_5	1408433.JHXV01000005_gene2237	7.518e-54	210.0	2ENP2@1|root,33GAE@2|Bacteria,4NZIT@976|Bacteroidetes,1I8VS@117743|Flavobacteriia,2PB29@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8004553_9	1267211.KI669560_gene1387	7.755e-08	59.0	COG2827@1|root,COG2827@2|Bacteria,4NUN3@976|Bacteroidetes,1IUCP@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Excinuclease ABC, C subunit	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
TLS3_k127_8004553_8	391596.PBAL39_00365	7.071e-09	57.0	2DFDT@1|root,2ZRHG@2|Bacteria,4P6Y0@976|Bacteroidetes,1J02T@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8004553_7	376686.Fjoh_4051	4.41e-44	181.0	COG2911@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG3391@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2P0KB@237|Flavobacterium	976|Bacteroidetes	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
TLS3_k127_8019544_2	1408433.JHXV01000002_gene359	7.945e-39	153.0	2BBSK@1|root,32XPV@2|Bacteria,4NSW3@976|Bacteroidetes,1IKDA@117743|Flavobacteriia,2PB42@246874|Cryomorphaceae	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_8019544_0	1121895.Q765_10435	1.66e-151	499.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,4NFCF@976|Bacteroidetes,1HWJE@117743|Flavobacteriia,2NSE8@237|Flavobacterium	976|Bacteroidetes	P	Transporter	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
TLS3_k127_8019544_4	411154.GFO_3145	8.964e-18	86.0	2E3D8@1|root,32YCF@2|Bacteria,4NUPM@976|Bacteroidetes,1I544@117743|Flavobacteriia	976|Bacteroidetes	S	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_2
TLS3_k127_8019544_1	1406840.Q763_06185	4.614e-122	398.0	COG0484@1|root,COG0484@2|Bacteria,4NE4X@976|Bacteroidetes,1HXJ8@117743|Flavobacteriia,2NTKH@237|Flavobacterium	976|Bacteroidetes	O	Molecular chaperone DnaJ	dnaJ2	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
TLS3_k127_8042302_10	929556.Solca_3745	4.816e-08	58.0	COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,1ITNF@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD2	-	-	-	-	-	-	-	-	-	-	-	ExbD
TLS3_k127_8042302_8	1121481.AUAS01000003_gene3861	2.219e-51	191.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,47XHA@768503|Cytophagia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_8042302_9	1356852.N008_06145	9.886e-32	138.0	COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes,47NNB@768503|Cytophagia	976|Bacteroidetes	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
TLS3_k127_8042302_4	755732.Fluta_1111	7.409e-89	316.0	COG0457@1|root,COG0457@2|Bacteria,4NIEU@976|Bacteroidetes,1IIYJ@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
TLS3_k127_8042302_1	1408473.JHXO01000009_gene3352	1.182e-151	512.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,2FM9F@200643|Bacteroidia	976|Bacteroidetes	M	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8042302_6	926562.Oweho_0210	6.085e-68	252.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,1HX7G@117743|Flavobacteriia,2PAR3@246874|Cryomorphaceae	976|Bacteroidetes	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
TLS3_k127_8042302_0	269798.CHU_3614	1.119e-187	597.0	COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,47K0I@768503|Cytophagia	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
TLS3_k127_8042302_3	755732.Fluta_1546	1.328e-98	327.0	COG3279@1|root,COG3279@2|Bacteria,4NKXC@976|Bacteroidetes,1I0BK@117743|Flavobacteriia,2PAUQ@246874|Cryomorphaceae	976|Bacteroidetes	K	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_8042302_5	877455.Metbo_0757	2.185e-72	276.0	COG0784@1|root,arCOG02348@1|root,arCOG06712@1|root,arCOG02348@2157|Archaea,arCOG02393@2157|Archaea,arCOG06712@2157|Archaea	2157|Archaea	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_8042302_2	926562.Oweho_2308	1.089e-111	380.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia,2PBM8@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_8042302_7	1267211.KI669560_gene524	2.267e-60	211.0	COG0379@1|root,COG0379@2|Bacteria,4NDVX@976|Bacteroidetes,1INZ3@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
TLS3_k127_8050318_4	1380384.JADN01000006_gene2683	3.411e-146	472.0	COG0334@1|root,COG0334@2|Bacteria,4NF3I@976|Bacteroidetes,1HX8R@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
TLS3_k127_8050318_2	926562.Oweho_0868	9.165e-181	583.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,1HWU3@117743|Flavobacteriia,2PAE4@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase and permease	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
TLS3_k127_8050318_8	1168034.FH5T_16685	6.19e-51	190.0	COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,2FMIT@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TLS3_k127_8050318_10	1168034.FH5T_06710	1.239e-08	64.0	COG4978@1|root,COG4978@2|Bacteria,4NFPM@976|Bacteroidetes	976|Bacteroidetes	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Cass2,GyrI-like,Polyketide_cyc2
TLS3_k127_8050318_3	1267211.KI669560_gene2552	6.965e-178	565.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1IPSR@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_8050318_1	714943.Mucpa_4144	5.266e-203	648.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1IQEP@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
TLS3_k127_8050318_5	1408813.AYMG01000034_gene4497	8.265e-130	423.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,1INM4@117747|Sphingobacteriia	976|Bacteroidetes	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
TLS3_k127_8050318_9	1121889.AUDM01000002_gene423	1.547e-28	127.0	COG2913@1|root,COG2913@2|Bacteria,4NP4N@976|Bacteroidetes,1I2RK@117743|Flavobacteriia	976|Bacteroidetes	J	Domain of unknown function (DUF4476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4476,SmpA_OmlA
TLS3_k127_8050318_6	929556.Solca_3658	7.288e-116	379.0	COG1741@1|root,COG1741@2|Bacteria,4NFZD@976|Bacteroidetes,1IPEQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
TLS3_k127_8050318_0	926562.Oweho_1923	7.089e-319	983.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1HXYZ@117743|Flavobacteriia,2PAMC@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Cytochrome C and Quinol oxidase polypeptide I	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
TLS3_k127_8050318_7	1094466.KQS_01695	6.389e-96	323.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,1HWR6@117743|Flavobacteriia,2NSKY@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome c oxidase subunit	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
TLS3_k127_8053078_2	153721.MYP_3133	1.816e-56	200.0	COG3384@1|root,COG3384@2|Bacteria,4NFGT@976|Bacteroidetes,47KW5@768503|Cytophagia	976|Bacteroidetes	S	PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
TLS3_k127_8053078_0	925409.KI911562_gene1788	9.25e-113	374.0	COG0859@1|root,COG0859@2|Bacteria,4PKBY@976|Bacteroidetes,1IWTZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
TLS3_k127_8053078_1	1189620.AJXL01000085_gene123	1.199e-88	296.0	COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,1HYKM@117743|Flavobacteriia,2NTPY@237|Flavobacterium	976|Bacteroidetes	FJ	tRNA hydroxylase	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
TLS3_k127_8053078_3	468059.AUHA01000002_gene610	1.271e-44	168.0	COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,1IPGI@117747|Sphingobacteriia	976|Bacteroidetes	H	Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase	-	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
TLS3_k127_8087356_0	1288963.ADIS_3894	2.838e-62	232.0	COG5433@1|root,COG5433@2|Bacteria,4P5P2@976|Bacteroidetes	976|Bacteroidetes	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8087470_6	1122176.KB903541_gene268	8.758e-40	151.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NEK7@976|Bacteroidetes,1IQQR@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
TLS3_k127_8087470_9	215803.DB30_5964	3.206e-11	72.0	COG4430@1|root,COG4430@2|Bacteria	2|Bacteria	F	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,DUF1905,OmdA
TLS3_k127_8087470_8	1196029.ALIM01000034_gene1568	1.053e-29	126.0	COG0202@1|root,COG0202@2|Bacteria,1VD02@1239|Firmicutes,4HKNS@91061|Bacilli,1ZII0@1386|Bacillus	91061|Bacilli	K	COG0202 DNA-directed RNA polymerase, alpha subunit 40 kD subunit	-	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_A_CTD
TLS3_k127_8087470_10	649349.Lbys_0225	6.622e-06	55.0	2CBZZ@1|root,32QA1@2|Bacteria,4NQPJ@976|Bacteroidetes,47QN2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8087470_4	643867.Ftrac_1682	7.152e-73	251.0	29X2E@1|root,30IQW@2|Bacteria,4P919@976|Bacteroidetes,47WI2@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
TLS3_k127_8087470_1	926549.KI421517_gene1504	8.826e-143	473.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,47JI8@768503|Cytophagia	976|Bacteroidetes	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
TLS3_k127_8087470_7	649349.Lbys_3460	8.613e-32	130.0	COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,47R38@768503|Cytophagia	976|Bacteroidetes	J	PFAM translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
TLS3_k127_8087470_0	1408433.JHXV01000001_gene862	2.594e-160	524.0	COG1680@1|root,COG1680@2|Bacteria,4PI0G@976|Bacteroidetes,1ICDB@117743|Flavobacteriia,2PBYK@246874|Cryomorphaceae	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_8087470_2	929556.Solca_0238	3.358e-102	335.0	COG0450@1|root,COG0450@2|Bacteria,4NEDT@976|Bacteroidetes,1IPHX@117747|Sphingobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
TLS3_k127_8087470_5	929562.Emtol_2629	9.61e-56	199.0	COG1225@1|root,COG1225@2|Bacteria,4NNHI@976|Bacteroidetes,47PTD@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
TLS3_k127_8087470_3	742726.HMPREF9448_00937	5.14e-83	279.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,2FMS7@200643|Bacteroidia,22WJC@171551|Porphyromonadaceae	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
TLS3_k127_8105095_4	266748.HY04_13295	2.929e-08	58.0	COG1028@1|root,COG1028@2|Bacteria,4NFXD@976|Bacteroidetes,1HX5Z@117743|Flavobacteriia,3ZR37@59732|Chryseobacterium	976|Bacteroidetes	IQ	Fungal family of unknown function (DUF1776)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_8105095_2	1121104.AQXH01000002_gene696	1.326e-41	158.0	COG3476@1|root,COG3476@2|Bacteria,4NP0D@976|Bacteroidetes,1ITBI@117747|Sphingobacteriia	976|Bacteroidetes	T	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	tspO	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
TLS3_k127_8105095_0	765914.ThisiDRAFT_2526	1.525e-60	214.0	COG4276@1|root,COG4276@2|Bacteria,1N2Z3@1224|Proteobacteria,1SRI2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8105095_5	984262.SGRA_3635	5.956e-07	57.0	2EKBS@1|root,33E25@2|Bacteria,4NYC7@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
TLS3_k127_8105095_1	620914.JH621288_gene1390	7.425e-57	211.0	COG3828@1|root,COG3828@2|Bacteria,4NDVK@976|Bacteroidetes,1IE7F@117743|Flavobacteriia,2YKQG@290174|Aquimarina	976|Bacteroidetes	G	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	DUF1080,ThuA
TLS3_k127_8105095_3	1086011.HJ01_03461	1.185e-26	111.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,4PKV1@976|Bacteroidetes,1IKKI@117743|Flavobacteriia,2P0QX@237|Flavobacterium	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_8174720_6	1408813.AYMG01000023_gene2036	4.156e-05	46.0	COG3291@1|root,COG3291@2|Bacteria,4NNVK@976|Bacteroidetes,1ISKM@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
TLS3_k127_8174720_3	1408433.JHXV01000010_gene636	3.458e-73	252.0	COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,1HYQJ@117743|Flavobacteriia,2PAQ8@246874|Cryomorphaceae	976|Bacteroidetes	S	O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
TLS3_k127_8174720_1	755732.Fluta_0615	6.413e-83	278.0	28M4Q@1|root,2ZAIK@2|Bacteria,4NJC3@976|Bacteroidetes,1IMPU@117743|Flavobacteriia,2PATN@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8174720_2	1506583.JQJY01000005_gene2330	1.568e-82	283.0	COG0463@1|root,COG0463@2|Bacteria,4NNK6@976|Bacteroidetes,1IK0D@117743|Flavobacteriia,2NXAE@237|Flavobacterium	976|Bacteroidetes	M	Core-2/I-Branching enzyme	-	-	2.4.2.26	ko:K00771	ko00532,ko00534,ko01100,map00532,map00534,map01100	M00057	R05925	-	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT14	-	Branch
TLS3_k127_8174720_4	56780.SYN_00825	1.481e-56	207.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,42SZT@68525|delta/epsilon subdivisions,2WIVA@28221|Deltaproteobacteria,2MQKX@213462|Syntrophobacterales	28221|Deltaproteobacteria	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
TLS3_k127_8174720_0	272134.KB731324_gene1022	2.8e-104	353.0	COG1134@1|root,COG1134@2|Bacteria,1G28R@1117|Cyanobacteria,1H8CS@1150|Oscillatoriales	1117|Cyanobacteria	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
TLS3_k127_8174720_5	485918.Cpin_3712	3.223e-21	101.0	COG0500@1|root,COG2226@2|Bacteria,4NIQW@976|Bacteroidetes	976|Bacteroidetes	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_8188947_0	319225.Plut_1857	4.918e-91	317.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
TLS3_k127_820556_3	755732.Fluta_3556	7.049e-51	188.0	29N3N@1|root,32D2M@2|Bacteria,4NRTM@976|Bacteroidetes,1ICPZ@117743|Flavobacteriia,2PBKH@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_820556_0	1131812.JQMS01000001_gene2440	1.509e-160	518.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,1HWWM@117743|Flavobacteriia,2NSYU@237|Flavobacterium	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
TLS3_k127_820556_1	411476.BACOVA_02512	1.405e-82	284.0	COG2326@1|root,COG2326@2|Bacteria,4NFJ5@976|Bacteroidetes,2FND3@200643|Bacteroidia,4AQ1H@815|Bacteroidaceae	976|Bacteroidetes	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
TLS3_k127_820556_2	1121890.AUDO01000007_gene2435	6.946e-64	223.0	COG0783@1|root,COG0783@2|Bacteria,4NNG4@976|Bacteroidetes,1I3MN@117743|Flavobacteriia,2NTUN@237|Flavobacterium	976|Bacteroidetes	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
TLS3_k127_820556_4	1131812.JQMS01000001_gene2157	4.783e-43	162.0	COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes,1HYFK@117743|Flavobacteriia,2NWFB@237|Flavobacterium	976|Bacteroidetes	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
TLS3_k127_8210956_4	926562.Oweho_2395	5.881e-44	166.0	COG1595@1|root,COG1595@2|Bacteria,4NKHT@976|Bacteroidetes,1IG88@117743|Flavobacteriia,2PB14@246874|Cryomorphaceae	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_8210956_2	929556.Solca_4382	7.833e-124	408.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,1IP1J@117747|Sphingobacteriia	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
TLS3_k127_8210956_5	926562.Oweho_1060	1.074e-42	166.0	COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,1IJP8@117743|Flavobacteriia,2PB5D@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
TLS3_k127_8210956_3	1048983.EL17_12335	6.263e-61	214.0	COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes,47PCJ@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
TLS3_k127_8210956_0	313606.M23134_02874	2.067e-197	627.0	COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,47JD2@768503|Cytophagia	976|Bacteroidetes	H	magnesium chelatase	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Sigma54_activat
TLS3_k127_8210956_6	1313172.YM304_07620	9.313e-33	141.0	COG4867@1|root,COG4867@2|Bacteria,2H14W@201174|Actinobacteria,4CMU5@84992|Acidimicrobiia	84992|Acidimicrobiia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8210956_7	1216967.L100_02692	5.244e-16	81.0	COG3668@1|root,COG3668@2|Bacteria,4NWEI@976|Bacteroidetes,1I50C@117743|Flavobacteriia	976|Bacteroidetes	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
TLS3_k127_8210956_1	468059.AUHA01000002_gene685	1.716e-172	549.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1IPDN@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_824410_0	269798.CHU_1228	1.782e-251	778.0	COG0538@1|root,COG0538@2|Bacteria,4NDY2@976|Bacteroidetes,47MTA@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
TLS3_k127_824410_5	929556.Solca_3902	1.33e-92	310.0	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,1INZC@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
TLS3_k127_824410_8	925409.KI911562_gene964	2.435e-13	72.0	2C4DF@1|root,32Z4B@2|Bacteria,4NWAX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_824410_6	1121481.AUAS01000006_gene581	8.356e-34	133.0	COG1569@1|root,COG1569@2|Bacteria,4NSFI@976|Bacteroidetes,47T2C@768503|Cytophagia	976|Bacteroidetes	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
TLS3_k127_824410_1	762903.Pedsa_2881	1.05e-245	799.0	COG5448@1|root,COG5448@2|Bacteria,4NGRS@976|Bacteroidetes,1J0Y6@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycoside hydrolase family 24	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_824410_3	643867.Ftrac_1756	2.527e-133	436.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47KGA@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	amaA	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_824410_7	1041826.FCOL_05205	4.648e-33	131.0	COG0730@1|root,COG0730@2|Bacteria,4NTZ8@976|Bacteroidetes,1I2UM@117743|Flavobacteriia,2NWMD@237|Flavobacterium	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_824410_2	926562.Oweho_1807	1.337e-208	687.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1I8E9@117743|Flavobacteriia,2PBCC@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM WD40-like beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_824410_4	509635.N824_07900	1.789e-104	353.0	COG4487@1|root,COG4487@2|Bacteria,4NGZ9@976|Bacteroidetes,1IQMR@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2130
TLS3_k127_824410_9	979556.MTES_2833	4.232e-11	64.0	COG2062@1|root,COG2062@2|Bacteria,2GJ0I@201174|Actinobacteria,4FQBH@85023|Microbacteriaceae	201174|Actinobacteria	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
TLS3_k127_8253881_2	1121899.Q764_04595	2.475e-11	65.0	COG2350@1|root,COG2350@2|Bacteria,4NVI4@976|Bacteroidetes,1I5WQ@117743|Flavobacteriia	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
TLS3_k127_8253881_1	1517682.HW49_10795	8.36e-24	111.0	2F61W@1|root,33YK8@2|Bacteria,4P4QF@976|Bacteroidetes,2FY5Q@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_827135_0	1408433.JHXV01000010_gene581	1.327e-167	562.0	COG3023@1|root,COG3227@1|root,COG3291@1|root,COG3023@2|Bacteria,COG3227@2|Bacteria,COG3291@2|Bacteria,4PI19@976|Bacteroidetes,1IG7F@117743|Flavobacteriia,2PBHU@246874|Cryomorphaceae	976|Bacteroidetes	E	Fungalysin/Thermolysin Propeptide Motif	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,Peptidase_M4,Peptidase_M4_C
TLS3_k127_827135_1	1434325.AZQN01000001_gene161	2.546e-93	311.0	COG1216@1|root,COG1216@2|Bacteria,4NGHQ@976|Bacteroidetes,47N3D@768503|Cytophagia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K13002	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
TLS3_k127_8276486_2	313606.M23134_04780	1.478e-17	83.0	COG1695@1|root,COG1695@2|Bacteria,4NQBA@976|Bacteroidetes,47QGA@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_8276486_1	755732.Fluta_0090	1.661e-61	226.0	COG4743@1|root,COG4743@2|Bacteria,4NU7A@976|Bacteroidetes,1I314@117743|Flavobacteriia,2PB9G@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1616)	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8276486_0	929562.Emtol_2945	4.802e-128	421.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,47N0I@768503|Cytophagia	976|Bacteroidetes	M	PFAM peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
TLS3_k127_8276486_3	1121129.KB903374_gene559	6.116e-08	60.0	2E8SV@1|root,3333M@2|Bacteria,4NSHV@976|Bacteroidetes,2FV1F@200643|Bacteroidia,22YEX@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4293
TLS3_k127_8288250_2	1168289.AJKI01000031_gene1078	1.532e-27	119.0	COG4206@1|root,COG4206@2|Bacteria,4NED9@976|Bacteroidetes,2FMA6@200643|Bacteroidia,3XJBS@558415|Marinilabiliaceae	976|Bacteroidetes	H	TonB-dependent Receptor Plug Domain	btuB	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
TLS3_k127_8288250_1	1408473.JHXO01000011_gene3075	2.604e-65	230.0	COG0566@1|root,COG0566@2|Bacteria,4NFH3@976|Bacteroidetes,2FSSX@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
TLS3_k127_8288250_0	743722.Sph21_1046	5.779e-103	346.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,1IR75@117747|Sphingobacteriia	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
TLS3_k127_8314232_0	743722.Sph21_1443	8.089e-229	718.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1INNX@117747|Sphingobacteriia	976|Bacteroidetes	O	chelatase, subunit chli	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
TLS3_k127_8314232_2	714943.Mucpa_4877	7.016e-105	351.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1IQ3N@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
TLS3_k127_8314232_1	1121373.KB903662_gene12	7.533e-110	362.0	COG0463@1|root,COG0463@2|Bacteria,4NEZP@976|Bacteroidetes,47MB5@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
TLS3_k127_8314232_3	926556.Echvi_2379	1.484e-58	210.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,47KRB@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
TLS3_k127_8320046_0	1122176.KB903537_gene1695	1.639e-120	403.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,1IWP1@117747|Sphingobacteriia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_8320046_2	269798.CHU_3371	8.554e-30	128.0	COG0671@1|root,COG0671@2|Bacteria,4NV5Q@976|Bacteroidetes,47R92@768503|Cytophagia	976|Bacteroidetes	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
TLS3_k127_8320046_1	216432.CA2559_06710	4.53e-107	353.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,1HWKT@117743|Flavobacteriia	976|Bacteroidetes	S	Pyrophosphatase	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
TLS3_k127_8320046_3	1121889.AUDM01000011_gene2755	2.698e-29	130.0	COG1317@1|root,COG1317@2|Bacteria,4PKYV@976|Bacteroidetes,1IKH3@117743|Flavobacteriia,2P0TV@237|Flavobacterium	976|Bacteroidetes	NU	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
TLS3_k127_8320046_4	643867.Ftrac_0720	2.581e-12	72.0	28PIV@1|root,2ZC8P@2|Bacteria,4NGE2@976|Bacteroidetes	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
TLS3_k127_8320439_0	313606.M23134_05475	3.408e-192	611.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47MEM@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
TLS3_k127_8324319_0	1121904.ARBP01000016_gene5289	5.146e-130	432.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,47M2N@768503|Cytophagia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
TLS3_k127_8326799_5	391603.FBALC1_09912	1.465e-07	63.0	COG4886@1|root,COG4935@1|root,COG4886@2|Bacteria,COG4935@2|Bacteria,4NMJ3@976|Bacteroidetes,1I2GQ@117743|Flavobacteriia	976|Bacteroidetes	P	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cadherin,LRR_4,Laminin_G_3
TLS3_k127_8326799_6	755732.Fluta_0866	2.886e-06	57.0	COG2913@1|root,COG2913@2|Bacteria,4NP4N@976|Bacteroidetes,1I2RK@117743|Flavobacteriia	976|Bacteroidetes	J	Domain of unknown function (DUF4476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4476,SmpA_OmlA
TLS3_k127_8326799_7	1408433.JHXV01000004_gene3422	4.227e-05	56.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HWJR@117743|Flavobacteriia,2PBB9@246874|Cryomorphaceae	976|Bacteroidetes	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Peptidase_M43
TLS3_k127_8326799_0	926549.KI421517_gene841	1.167e-211	664.0	COG0677@1|root,COG0677@2|Bacteria,4NDTW@976|Bacteroidetes,47JKM@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TLS3_k127_8326799_1	755732.Fluta_2062	1.075e-154	496.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,1I19J@117743|Flavobacteriia,2PAIR@246874|Cryomorphaceae	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_8326799_4	938709.AUSH02000020_gene2014	2.571e-60	214.0	COG0449@1|root,COG0449@2|Bacteria,4P1TS@976|Bacteroidetes	976|Bacteroidetes	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
TLS3_k127_8326799_3	525257.HMPREF0204_12129	2.681e-96	317.0	COG0110@1|root,COG0110@2|Bacteria,4NENC@976|Bacteroidetes,1HZ0I@117743|Flavobacteriia,3ZS2S@59732|Chryseobacterium	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
TLS3_k127_8326799_2	1223410.KN050846_gene707	2.658e-114	388.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,1HX3C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
TLS3_k127_8328722_6	755732.Fluta_0800	8.665e-42	163.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,1HX7Z@117743|Flavobacteriia,2PAQ0@246874|Cryomorphaceae	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
TLS3_k127_8328722_5	755732.Fluta_0799	1.694e-47	179.0	28NAE@1|root,2ZBE7@2|Bacteria,4NJNX@976|Bacteroidetes,1I6YH@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (Porph_ging)	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
TLS3_k127_8328722_7	485918.Cpin_4897	1.876e-36	145.0	COG1309@1|root,COG1309@2|Bacteria,4NP1K@976|Bacteroidetes,1ISE7@117747|Sphingobacteriia	976|Bacteroidetes	K	regulatory protein TetR	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
TLS3_k127_8328722_2	760192.Halhy_4832	1.15e-90	305.0	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,1INMV@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
TLS3_k127_8328722_3	742817.HMPREF9449_02759	1.328e-57	204.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,2FS3I@200643|Bacteroidia,22XMC@171551|Porphyromonadaceae	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
TLS3_k127_8328722_4	1538644.KO02_18840	3.003e-48	175.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,1ISJG@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
TLS3_k127_8328722_0	626522.GCWU000325_01209	5.263e-105	347.0	COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia,1WCQ0@1283313|Alloprevotella	976|Bacteroidetes	J	Ribosomal protein S2	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
TLS3_k127_8328722_1	743722.Sph21_1444	1.938e-103	344.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,1IP5Z@117747|Sphingobacteriia	976|Bacteroidetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
TLS3_k127_8328722_8	236814.IX39_11450	2.473e-25	107.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1HXVS@117743|Flavobacteriia,3ZPQR@59732|Chryseobacterium	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
TLS3_k127_8337027_5	1123248.KB893348_gene130	4.41e-15	78.0	COG4980@1|root,COG4980@2|Bacteria,4NXB3@976|Bacteroidetes,1ITYD@117747|Sphingobacteriia	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
TLS3_k127_8337027_4	927658.AJUM01000037_gene1869	3.382e-15	76.0	2EFZF@1|root,339RM@2|Bacteria,4NXMV@976|Bacteroidetes,2FZWY@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
TLS3_k127_8337027_2	1538644.KO02_17375	4.986e-30	123.0	2C0VV@1|root,32R2M@2|Bacteria,4NQM5@976|Bacteroidetes,1ITKS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8337027_0	938709.AUSH02000031_gene1299	3.522e-68	238.0	2DSRE@1|root,33H63@2|Bacteria	2|Bacteria	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_8337027_3	755732.Fluta_3075	5.976e-18	90.0	2DRAU@1|root,33B03@2|Bacteria,4NXX1@976|Bacteroidetes,1IBMT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8337027_6	1144313.PMI10_04261	3.666e-11	63.0	COG3237@1|root,COG3237@2|Bacteria,4NUMZ@976|Bacteroidetes,1I57R@117743|Flavobacteriia,2NXG5@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
TLS3_k127_833989_3	1408433.JHXV01000038_gene2198	2.199e-74	279.0	COG2885@1|root,COG2885@2|Bacteria,4NRRF@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
TLS3_k127_833989_9	1189620.AJXL01000023_gene2929	3.539e-05	56.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,1HX7G@117743|Flavobacteriia,2NSP4@237|Flavobacterium	976|Bacteroidetes	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
TLS3_k127_833989_2	1313421.JHBV01000029_gene1929	2.369e-104	345.0	COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,1IRUS@117747|Sphingobacteriia	976|Bacteroidetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_833989_4	929562.Emtol_1334	5.15e-32	130.0	COG2137@1|root,COG2137@2|Bacteria,4NSAS@976|Bacteroidetes,47QBK@768503|Cytophagia	976|Bacteroidetes	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
TLS3_k127_833989_1	743722.Sph21_0573	2.216e-118	394.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,4NEV7@976|Bacteroidetes,1IPRI@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Bacterial Fmu (Sun) eukaryotic nucleolar NOL1 Nop2p	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA
TLS3_k127_833989_0	929562.Emtol_1522	9.76e-224	696.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,47JYT@768503|Cytophagia	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
TLS3_k127_833989_6	1121129.KB903374_gene570	1.597e-13	72.0	COG0690@1|root,COG0690@2|Bacteria,4NUSJ@976|Bacteroidetes,2FV3K@200643|Bacteroidia,231R0@171551|Porphyromonadaceae	976|Bacteroidetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
TLS3_k127_833989_5	929704.Myrod_1260	3.374e-16	79.0	COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,1HWPB@117743|Flavobacteriia,47HEG@76831|Myroides	976|Bacteroidetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
TLS3_k127_8348671_5	926562.Oweho_2632	8.38e-38	145.0	COG3781@1|root,COG3781@2|Bacteria,4NEB1@976|Bacteroidetes,1HYDP@117743|Flavobacteriia,2PAP9@246874|Cryomorphaceae	976|Bacteroidetes	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
TLS3_k127_8348671_0	1121931.AUHG01000020_gene3167	2.473e-108	364.0	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,1HZBE@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the methyltransferase superfamily	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
TLS3_k127_8348671_2	755732.Fluta_2607	4.293e-75	258.0	COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,1IMQY@117743|Flavobacteriia,2PBHE@246874|Cryomorphaceae	976|Bacteroidetes	H	2-phosphosulpholactate phosphatase	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
TLS3_k127_8348671_1	761193.Runsl_4187	6.814e-78	265.0	COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,47KZ6@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
TLS3_k127_8348671_3	1123373.ATXI01000008_gene1561	8.27e-58	209.0	COG1208@1|root,COG1208@2|Bacteria,2GI50@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
TLS3_k127_8348671_4	1267211.KI669560_gene1738	1.167e-46	175.0	COG0241@1|root,COG0241@2|Bacteria,4NR54@976|Bacteroidetes,1IU3D@117747|Sphingobacteriia	976|Bacteroidetes	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like,PNK3P
TLS3_k127_8366822_9	1144313.PMI10_00113	1.185e-40	152.0	COG2353@1|root,COG2353@2|Bacteria,4NNMD@976|Bacteroidetes,1I18S@117743|Flavobacteriia,2NSUY@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_8366822_10	886379.AEWI01000043_gene3331	9.69e-36	140.0	COG1051@1|root,COG1051@2|Bacteria,4NR5C@976|Bacteroidetes,2FYDH@200643|Bacteroidia,3XK6A@558415|Marinilabiliaceae	976|Bacteroidetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_8366822_1	926562.Oweho_2942	1.211e-235	754.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,1HYJ3@117743|Flavobacteriia,2PAHE@246874|Cryomorphaceae	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
TLS3_k127_8366822_6	1121007.AUML01000003_gene2548	1.284e-81	280.0	COG0730@1|root,COG0730@2|Bacteria,4NKE8@976|Bacteroidetes,1II62@117743|Flavobacteriia,2YI1D@290174|Aquimarina	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_8366822_8	1121904.ARBP01000009_gene4379	1.716e-51	190.0	2DICZ@1|root,32UAY@2|Bacteria,4NU7D@976|Bacteroidetes,47SYM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8366822_5	649349.Lbys_2651	7.195e-100	330.0	COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes,47JE4@768503|Cytophagia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
TLS3_k127_8366822_11	760192.Halhy_1931	7.814e-32	141.0	COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,1INTW@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	tolC	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_8366822_0	929556.Solca_3158	0.0	1323.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IP63@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bepE_4	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
TLS3_k127_8366822_7	471854.Dfer_3208	2.883e-70	250.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,47KNA@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
TLS3_k127_8366822_3	929562.Emtol_0645	7.088e-158	505.0	COG0823@1|root,COG0823@2|Bacteria,4PMAE@976|Bacteroidetes,47NZ3@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_8366822_4	32057.KB217478_gene1822	6.73e-112	373.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wgaB	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
TLS3_k127_8366822_2	929556.Solca_3427	4.873e-170	538.0	COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,1IPGW@117747|Sphingobacteriia	976|Bacteroidetes	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
TLS3_k127_8431236_0	398720.MED217_01780	2.172e-66	251.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia,2XJV3@283735|Leeuwenhoekiella	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
TLS3_k127_8448541_1	1131812.JQMS01000001_gene2614	4.191e-105	348.0	COG1629@1|root,COG4771@2|Bacteria,4NE4M@976|Bacteroidetes,1HWRH@117743|Flavobacteriia,2NUQH@237|Flavobacterium	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_8448541_0	1131812.JQMS01000001_gene2614	8.035e-159	515.0	COG1629@1|root,COG4771@2|Bacteria,4NE4M@976|Bacteroidetes,1HWRH@117743|Flavobacteriia,2NUQH@237|Flavobacterium	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_8457271_0	1313421.JHBV01000014_gene3931	1.984e-84	292.0	COG3291@1|root,COG3291@2|Bacteria,4NJ39@976|Bacteroidetes	976|Bacteroidetes	C	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Beta_helix,DUF4465
TLS3_k127_8457271_1	926562.Oweho_3113	1.776e-07	59.0	COG1807@1|root,COG1807@2|Bacteria,4P3XI@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_8470174_1	926562.Oweho_1583	1.086e-121	397.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,1HX2U@117743|Flavobacteriia,2PAHJ@246874|Cryomorphaceae	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
TLS3_k127_8470174_4	143224.JQMD01000002_gene1059	3.408e-33	133.0	COG4096@1|root,COG4096@2|Bacteria,4NNKI@976|Bacteroidetes,1I22N@117743|Flavobacteriia	976|Bacteroidetes	V	Restriction endonuclease, type I, EcoRI, R subunit Type III, Res subunit, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
TLS3_k127_8470174_0	264462.Bd1233	3.694e-126	407.0	COG2820@1|root,COG2820@2|Bacteria,1QVR4@1224|Proteobacteria,42N9X@68525|delta/epsilon subdivisions,2MSXM@213481|Bdellovibrionales,2WJ8F@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	Phosphorylase superfamily	-	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
TLS3_k127_8470174_2	1121904.ARBP01000001_gene5363	1.444e-107	358.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,47M9T@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM LAO AO transport system ATPase	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
TLS3_k127_8470174_3	1305737.JAFX01000001_gene3507	4.279e-39	145.0	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,47R0I@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
TLS3_k127_8471888_3	927658.AJUM01000022_gene1260	4.598e-87	291.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,2FX71@200643|Bacteroidia,3XJTK@558415|Marinilabiliaceae	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
TLS3_k127_8471888_7	269798.CHU_3758	6.198e-06	55.0	2F6F7@1|root,33YYB@2|Bacteria,4P4A5@976|Bacteroidetes,47VFF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8471888_0	525373.HMPREF0766_10718	8.085e-188	594.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1IPEJ@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
TLS3_k127_8471888_4	929703.KE386491_gene3346	2.489e-84	285.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,47PB4@768503|Cytophagia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
TLS3_k127_8471888_5	743722.Sph21_1544	3.917e-75	256.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,1IP45@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
TLS3_k127_8471888_1	1453500.AT05_09010	4.392e-147	471.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,1HXWT@117743|Flavobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
TLS3_k127_8471888_6	926549.KI421517_gene1618	1.279e-50	189.0	2DBUB@1|root,2ZB53@2|Bacteria,4NMWS@976|Bacteroidetes,47P3Z@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8471888_2	925409.KI911562_gene1304	1.462e-97	329.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1IW4H@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
TLS3_k127_8477957_0	1121904.ARBP01000002_gene7078	6.101e-117	392.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,47N1D@768503|Cytophagia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	LAB_N,PMT,PMT_2
TLS3_k127_8477957_1	471854.Dfer_1942	6.197e-21	108.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin-like,SLH,TSP_3
TLS3_k127_8521289_1	1150600.ADIARSV_1493	2.978e-08	64.0	28H89@1|root,2Z7K8@2|Bacteria,4NEKX@976|Bacteroidetes,1IPQD@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8521289_0	1121007.AUML01000005_gene2264	3.076e-146	473.0	COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,1HWQ8@117743|Flavobacteriia,2YJ6T@290174|Aquimarina	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_8527623_0	313598.MED152_04045	1.421e-138	447.0	COG0463@1|root,COG0463@2|Bacteria,4NEVT@976|Bacteroidetes,1HXT8@117743|Flavobacteriia,3VVID@52959|Polaribacter	976|Bacteroidetes	M	Glycosyltransferase like family 2	arnC	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_8527623_3	313598.MED152_01785	1.121e-56	204.0	COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,1HX2Z@117743|Flavobacteriia,3VVZ7@52959|Polaribacter	976|Bacteroidetes	K	ECF sigma factor	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS3_k127_8527623_1	1408433.JHXV01000015_gene1752	2.87e-90	304.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,1HX74@117743|Flavobacteriia,2PAQ1@246874|Cryomorphaceae	976|Bacteroidetes	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
TLS3_k127_8527623_2	700598.Niako_4140	5.054e-76	264.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1IPHN@117747|Sphingobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
TLS3_k127_8530686_2	1453505.JASY01000001_gene3162	2.303e-26	109.0	COG2249@1|root,COG2249@2|Bacteria,4NGIK@976|Bacteroidetes,1I0BM@117743|Flavobacteriia,2NVCG@237|Flavobacterium	976|Bacteroidetes	S	NADPH-quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
TLS3_k127_8530686_0	1034807.FBFL15_2173	1.47e-72	256.0	COG2972@1|root,COG2972@2|Bacteria,4NMDQ@976|Bacteroidetes,1I1GC@117743|Flavobacteriia,2NU5R@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_8530686_1	1131812.JQMS01000001_gene2617	1.139e-57	207.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,1INEJ@117743|Flavobacteriia,2NWTT@237|Flavobacterium	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_8537119_3	1356852.N008_08500	2.681e-07	62.0	COG1404@1|root,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,47X9G@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Peptidase_S8
TLS3_k127_8537119_1	755732.Fluta_1672	3.431e-20	102.0	COG2885@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,4NKCW@976|Bacteroidetes,1HXSH@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM Outer membrane protein, OmpA MotB, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
TLS3_k127_8537119_2	714943.Mucpa_0105	6.144e-08	64.0	COG2885@1|root,COG2885@2|Bacteria,4NYQV@976|Bacteroidetes	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8537119_0	313606.M23134_06828	6.872e-43	164.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,47PTI@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_8541334_2	1121904.ARBP01000002_gene6820	6.306e-14	76.0	2BZ54@1|root,33EXY@2|Bacteria,4NY89@976|Bacteroidetes,47WZF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8541334_1	269798.CHU_0537	4.722e-114	380.0	COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,47K2C@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
TLS3_k127_8541334_0	247490.KSU1_D1002	0.0	1020.0	COG0841@1|root,COG0841@2|Bacteria,2IX2G@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
TLS3_k127_8541663_1	1089547.KB913013_gene2855	3.797e-63	222.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,47KJJ@768503|Cytophagia	976|Bacteroidetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
TLS3_k127_8541663_0	694427.Palpr_1191	1.224e-87	300.0	COG0438@1|root,COG0438@2|Bacteria,4NH7K@976|Bacteroidetes,2FSCQ@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_8545938_4	649349.Lbys_0843	1.138e-83	291.0	COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,47K0R@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
TLS3_k127_8545938_2	1122621.ATZA01000040_gene2426	7.341e-128	412.0	COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes,1IQTA@117747|Sphingobacteriia	976|Bacteroidetes	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
TLS3_k127_8545938_6	1121373.KB903632_gene581	2.129e-28	132.0	COG1807@1|root,COG1807@2|Bacteria,4NPS7@976|Bacteroidetes,47V6I@768503|Cytophagia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8545938_0	1123037.AUDE01000032_gene2265	5.406e-264	818.0	COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,1HWKU@117743|Flavobacteriia	976|Bacteroidetes	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
TLS3_k127_8545938_5	1123037.AUDE01000032_gene2267	5.576e-49	177.0	COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,1I2SJ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the HesB IscA family	sufA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
TLS3_k127_8545938_1	1305737.JAFX01000001_gene3229	1.031e-237	745.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,47JQE@768503|Cytophagia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
TLS3_k127_8545938_3	269798.CHU_1561	3.514e-97	339.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4P1P3@976|Bacteroidetes,47THG@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
TLS3_k127_8569324_6	926562.Oweho_3079	1.821e-05	46.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,1HWR7@117743|Flavobacteriia,2PA4H@246874|Cryomorphaceae	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
TLS3_k127_8569324_4	1046627.BZARG_860	8.428e-37	139.0	COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,1I3WQ@117743|Flavobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
TLS3_k127_8569324_5	906888.JCM19314_1736	1.187e-13	70.0	COG0257@1|root,COG0257@2|Bacteria,4NXGE@976|Bacteroidetes,1I6A2@117743|Flavobacteriia,3HKTC@363408|Nonlabens	976|Bacteroidetes	J	Ribosomal protein L36	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
TLS3_k127_8569324_3	925409.KI911562_gene1887	1.674e-53	190.0	COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,1ISH0@117747|Sphingobacteriia	976|Bacteroidetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
TLS3_k127_8569324_2	1121899.Q764_08200	2.372e-61	213.0	COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,1I1GI@117743|Flavobacteriia,2NVW9@237|Flavobacterium	976|Bacteroidetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
TLS3_k127_8569324_1	1538644.KO02_02460	7.483e-93	308.0	COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,1INSQ@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
TLS3_k127_8569324_0	926562.Oweho_3085	4.195e-136	437.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,1HX6J@117743|Flavobacteriia,2PA8U@246874|Cryomorphaceae	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
TLS3_k127_8573858_0	929556.Solca_2297	8.652e-278	887.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1IP7W@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
TLS3_k127_8573858_4	1121011.AUCB01000047_gene15	8.911e-141	455.0	COG3177@1|root,COG3177@2|Bacteria,4NFBY@976|Bacteroidetes,1HXAM@117743|Flavobacteriia,23HJ5@178469|Arenibacter	976|Bacteroidetes	S	Fic/DOC family N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
TLS3_k127_8573858_2	929703.KE386491_gene695	7.795e-185	580.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,47JU8@768503|Cytophagia	976|Bacteroidetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
TLS3_k127_8573858_1	1356852.N008_04010	1.001e-214	673.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,47KAG@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TLS3_k127_8573858_3	1453500.AT05_09530	4.079e-167	533.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,1HXWJ@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_8573858_5	929556.Solca_1798	3.554e-39	149.0	COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,1IT5E@117747|Sphingobacteriia	976|Bacteroidetes	S	thioesterase	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
TLS3_k127_8586072_1	1123248.KB893359_gene2050	1.416e-18	97.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,1ISIV@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
TLS3_k127_8586072_0	1267211.KI669560_gene1859	0.0	1276.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1INUB@117747|Sphingobacteriia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
TLS3_k127_85881_0	762903.Pedsa_2670	0.0	1417.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1IPHM@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
TLS3_k127_86046_0	385682.AFSL01000060_gene1763	3.803e-229	718.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,2FMBR@200643|Bacteroidia,3XJ41@558415|Marinilabiliaceae	976|Bacteroidetes	L	RQC	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
TLS3_k127_86046_2	762903.Pedsa_1125	4.924e-132	432.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_86046_7	926562.Oweho_0083	1.236e-28	123.0	COG3117@1|root,COG3117@2|Bacteria,4P9FE@976|Bacteroidetes,1IDW5@117743|Flavobacteriia,2PB77@246874|Cryomorphaceae	976|Bacteroidetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
TLS3_k127_86046_4	762903.Pedsa_3216	4.095e-53	205.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1IPB7@117747|Sphingobacteriia	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_86046_3	985255.APHJ01000019_gene695	9.695e-56	207.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,1I1AK@117743|Flavobacteriia,2P5JK@244698|Gillisia	976|Bacteroidetes	K	Type III pantothenate kinase	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
TLS3_k127_86046_9	980584.AFPB01000149_gene531	5.079e-07	55.0	2DR32@1|root,339YJ@2|Bacteria,4NYM3@976|Bacteroidetes,1I6CH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_86046_8	1492737.FEM08_35000	5.249e-18	85.0	2AF0Z@1|root,314Z9@2|Bacteria,4P7CF@976|Bacteroidetes,1IAXW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_86046_5	616991.JPOO01000001_gene4468	6.103e-42	159.0	COG3603@1|root,COG3603@2|Bacteria	2|Bacteria	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_86046_6	572479.Hprae_1376	7.974e-31	124.0	COG3708@1|root,COG3708@2|Bacteria,1VJT1@1239|Firmicutes	1239|Firmicutes	K	Putative zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn_ribbon_2
TLS3_k127_86046_1	1443665.JACA01000007_gene184	5.093e-143	458.0	2C1EG@1|root,2Z7MZ@2|Bacteria,4NYQE@976|Bacteroidetes,1IBSY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_868228_1	1313421.JHBV01000029_gene1918	2.315e-55	199.0	COG0745@1|root,COG0745@2|Bacteria,4NGXP@976|Bacteroidetes,1INQ4@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_868228_0	1121285.AUFK01000013_gene2527	3.712e-318	983.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,4NI68@976|Bacteroidetes,1HXAQ@117743|Flavobacteriia,3ZNRY@59732|Chryseobacterium	976|Bacteroidetes	CI	Phenylacetic acid degradation protein PaaN	paaN	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,DUF1569,MaoC_dehydratas
TLS3_k127_883475_1	1408433.JHXV01000007_gene2884	3.049e-78	277.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia,2PACJ@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
TLS3_k127_883475_0	504487.JCM19302_2662	5.704e-169	569.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
TLS3_k127_965315_2	1048983.EL17_16645	7.315e-65	235.0	COG0438@1|root,COG0438@2|Bacteria,4NNVW@976|Bacteroidetes,47U22@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
TLS3_k127_965315_3	1123248.KB893348_gene336	1.457e-30	129.0	29CCT@1|root,2ZZB9@2|Bacteria,4NM9K@976|Bacteroidetes,1IRVA@117747|Sphingobacteriia	976|Bacteroidetes	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
TLS3_k127_965315_0	153721.MYP_2040	4.194e-125	404.0	COG0463@1|root,COG0463@2|Bacteria,4PKIQ@976|Bacteroidetes,47XX0@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_965315_1	929556.Solca_0221	3.115e-94	326.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1INY8@117747|Sphingobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
TLS3_k127_974921_8	385682.AFSL01000010_gene2398	4.626e-36	144.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,2FPS4@200643|Bacteroidia,3XJ68@558415|Marinilabiliaceae	976|Bacteroidetes	S	PASTA	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
TLS3_k127_974921_4	926562.Oweho_1744	1.719e-70	262.0	28M1N@1|root,2ZAGE@2|Bacteria,4NIDD@976|Bacteroidetes,1I8D6@117743|Flavobacteriia,2PARN@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_974921_1	709991.Odosp_1635	1.281e-135	440.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,2FMD1@200643|Bacteroidia,22W4T@171551|Porphyromonadaceae	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS3_k127_974921_6	1341155.FSS13T_25370	4.477e-62	238.0	COG0265@1|root,COG3291@1|root,COG0265@2|Bacteria,COG3291@2|Bacteria,4PKT1@976|Bacteroidetes,1I02G@117743|Flavobacteriia,2NV5H@237|Flavobacterium	976|Bacteroidetes	O	Pkd domain containing protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
TLS3_k127_974921_0	926562.Oweho_3015	1.498e-199	631.0	COG0277@1|root,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1HXIK@117743|Flavobacteriia,2PB4N@246874|Cryomorphaceae	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
TLS3_k127_974921_7	1034807.FBFL15_1084	1.494e-46	175.0	COG0084@1|root,COG0084@2|Bacteria,4NSGW@976|Bacteroidetes,1I2AW@117743|Flavobacteriia,2NT8M@237|Flavobacterium	976|Bacteroidetes	L	hydrolase, TatD	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
TLS3_k127_974921_3	929562.Emtol_3698	9.189e-92	307.0	COG1179@1|root,COG1179@2|Bacteria,4NEKB@976|Bacteroidetes,47KQ6@768503|Cytophagia	976|Bacteroidetes	H	ThiF family	tcdA	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
TLS3_k127_974921_2	755732.Fluta_2300	2.444e-115	374.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,1HWT0@117743|Flavobacteriia,2PA6J@246874|Cryomorphaceae	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
TLS3_k127_974921_5	1358423.N180_09700	1.431e-65	233.0	COG0115@1|root,COG0115@2|Bacteria,4NG0G@976|Bacteroidetes,1IPBG@117747|Sphingobacteriia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_986455_6	925409.KI911562_gene2863	1.943e-102	339.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1IWX4@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
TLS3_k127_986455_10	1166018.FAES_5382	3.665e-37	147.0	COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,47MSF@768503|Cytophagia	976|Bacteroidetes	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
TLS3_k127_986455_12	1239962.C943_00700	2.517e-21	100.0	2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,47RV6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_986455_9	1144313.PMI10_02921	7.191e-45	168.0	COG3646@1|root,COG3646@2|Bacteria,4PM3Z@976|Bacteroidetes,1IKR8@117743|Flavobacteriia,2P0UV@237|Flavobacterium	976|Bacteroidetes	S	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
TLS3_k127_986455_15	714943.Mucpa_1340	2.654e-08	56.0	COG1502@1|root,COG1502@2|Bacteria,4NMXS@976|Bacteroidetes,1ISBY@117747|Sphingobacteriia	976|Bacteroidetes	I	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
TLS3_k127_986455_8	435590.BVU_0469	6.431e-51	193.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,4NGHH@976|Bacteroidetes,2FMHT@200643|Bacteroidia,4AK8U@815|Bacteroidaceae	976|Bacteroidetes	M	Peptidase, M23	mepM_1	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
TLS3_k127_986455_14	4081.Solyc12g100030.1.1	5.276e-09	67.0	COG4886@1|root,KOG0619@2759|Eukaryota,37RSV@33090|Viridiplantae,3GF8S@35493|Streptophyta,44MPS@71274|asterids	35493|Streptophyta	S	Leucine rich repeat N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LRRNT_2,LRR_1,LRR_8
TLS3_k127_986455_5	592029.DDD_2164	8.828e-104	344.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,1HWWP@117743|Flavobacteriia,3HJW8@363408|Nonlabens	976|Bacteroidetes	E	Hydroxymethylglutaryl-CoA lyase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
TLS3_k127_986455_4	929556.Solca_2357	1.85e-127	417.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1IPRM@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
TLS3_k127_986455_7	1121875.KB907551_gene1007	1.013e-75	272.0	COG1468@1|root,COG1468@2|Bacteria,4PM88@976|Bacteroidetes,1IJMB@117743|Flavobacteriia	976|Bacteroidetes	L	Domain of unknown function(DUF2779)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779
TLS3_k127_986455_0	1349822.NSB1T_10675	1.695e-274	855.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,2FNIS@200643|Bacteroidia,22X8D@171551|Porphyromonadaceae	976|Bacteroidetes	S	ATP-binding cassette protein, ChvD family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_986455_13	247490.KSU1_C1331	5.928e-17	91.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_986455_2	929556.Solca_1244	4.358e-141	454.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1IQ1P@117747|Sphingobacteriia	976|Bacteroidetes	C	Thioredoxin reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_986455_3	688270.Celal_1654	4.515e-128	453.0	COG3735@1|root,COG3735@2|Bacteria,4NGNW@976|Bacteroidetes,1HYQT@117743|Flavobacteriia,1F8K4@104264|Cellulophaga	976|Bacteroidetes	S	TraB family	-	-	-	-	-	-	-	-	-	-	-	-	TraB
TLS3_k127_986455_1	755732.Fluta_0946	1.042e-147	473.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HXA1@117743|Flavobacteriia,2PA5W@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TLS3_k127_986455_16	1408473.JHXO01000004_gene133	1.44e-05	53.0	2EQMK@1|root,33I7I@2|Bacteria,4NY3R@976|Bacteroidetes,2FVUP@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_986455_11	1235803.C825_00886	1.561e-30	123.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,2FNZW@200643|Bacteroidia,22XA9@171551|Porphyromonadaceae	976|Bacteroidetes	C	NADH dehydrogenase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_989141_0	679935.Alfi_0293	1.114e-45	171.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,4NGA4@976|Bacteroidetes	976|Bacteroidetes	O	peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
## 2855 queries scanned
## Total time (seconds): 97.09291434288025
## Rate: 29.40 q/s