## Fri Nov 15 09:17:02 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin28/TLS_3_bin.20.fa -m mmseqs --itype genome -o TLS_3_bin.20 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/TLS_3_bin.20 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
TLS3_k127_1007474_2	404589.Anae109_4467	2.521e-78	267.0	COG1100@1|root,COG1100@2|Bacteria,1RCJJ@1224|Proteobacteria,42R57@68525|delta/epsilon subdivisions,2WN5Y@28221|Deltaproteobacteria,2YUYK@29|Myxococcales	28221|Deltaproteobacteria	S	Small GTP-binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
TLS3_k127_1007474_0	404589.Anae109_4466	7.281e-171	558.0	COG0642@1|root,COG4936@1|root,COG2205@2|Bacteria,COG4936@2|Bacteria,1NRP8@1224|Proteobacteria,42MZW@68525|delta/epsilon subdivisions,2WIV1@28221|Deltaproteobacteria,2YUVS@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PocR
TLS3_k127_1007474_1	290397.Adeh_4320	1.472e-104	352.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2WNGE@28221|Deltaproteobacteria,2YVMB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
TLS3_k127_1007474_3	290397.Adeh_4319	1.78e-70	265.0	COG0840@1|root,COG0840@2|Bacteria,1RA20@1224|Proteobacteria,42QNV@68525|delta/epsilon subdivisions,2WMT1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
TLS3_k127_1039337_2	290397.Adeh_2841	2.486e-78	264.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
TLS3_k127_1039337_1	290397.Adeh_2837	1.38e-108	376.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,42NY0@68525|delta/epsilon subdivisions,2X3G8@28221|Deltaproteobacteria,2YVYR@29|Myxococcales	28221|Deltaproteobacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
TLS3_k127_1039337_0	404589.Anae109_2766	1.459e-133	437.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42ZVA@68525|delta/epsilon subdivisions,2WVEX@28221|Deltaproteobacteria,2YU4Z@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
TLS3_k127_1039337_3	290397.Adeh_2832	2.123e-63	232.0	COG1835@1|root,COG1835@2|Bacteria,1Q5GA@1224|Proteobacteria,432FW@68525|delta/epsilon subdivisions,2WX8T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS3_k127_1039337_4	404589.Anae109_2761	4.181e-29	117.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,42PTC@68525|delta/epsilon subdivisions,2WM3S@28221|Deltaproteobacteria,2YTUU@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
TLS3_k127_1043430_5	215803.DB30_3937	6.769e-11	62.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,2YU7R@29|Myxococcales	28221|Deltaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
TLS3_k127_1043430_4	1207063.P24_05887	5.875e-40	161.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
TLS3_k127_1043430_0	404589.Anae109_0490	7.021e-207	651.0	COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,42Z8C@68525|delta/epsilon subdivisions,2WU08@28221|Deltaproteobacteria,2YXJP@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1043430_3	1207075.PputUW4_03483	5.366e-58	210.0	COG1376@1|root,COG1376@2|Bacteria,1RA7Q@1224|Proteobacteria,1S5JW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
TLS3_k127_1043430_2	1123368.AUIS01000008_gene2230	9.131e-69	246.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,1MVI4@1224|Proteobacteria,1S1IH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
TLS3_k127_1043430_1	290397.Adeh_4336	1.418e-120	398.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2WJGI@28221|Deltaproteobacteria,2YV17@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
TLS3_k127_1048646_2	290397.Adeh_0937	5.613e-86	291.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,42U7W@68525|delta/epsilon subdivisions,2WQ9A@28221|Deltaproteobacteria,2YVEF@29|Myxococcales	28221|Deltaproteobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
TLS3_k127_1048646_6	525146.Ddes_1121	1.59e-11	68.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42V5P@68525|delta/epsilon subdivisions,2WRM0@28221|Deltaproteobacteria,2MD43@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
TLS3_k127_1048646_5	290397.Adeh_0935	5.928e-25	117.0	2AKQ6@1|root,31BGX@2|Bacteria,1RCS3@1224|Proteobacteria,43CC0@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
TLS3_k127_1048646_3	290397.Adeh_0934	1.325e-72	257.0	COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,42WB9@68525|delta/epsilon subdivisions,2WSSJ@28221|Deltaproteobacteria,2YVJB@29|Myxococcales	28221|Deltaproteobacteria	S	PHB/PHA accumulation regulator DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc_N
TLS3_k127_1048646_1	290397.Adeh_0930	2.511e-104	350.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria	1224|Proteobacteria	D	Chromosome Partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
TLS3_k127_1048646_0	290397.Adeh_0929	8.252e-138	450.0	COG0003@1|root,COG0003@2|Bacteria,1NA7C@1224|Proteobacteria,42V2J@68525|delta/epsilon subdivisions,2WS25@28221|Deltaproteobacteria,2YUZS@29|Myxococcales	28221|Deltaproteobacteria	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
TLS3_k127_1048646_4	404589.Anae109_0971	1.653e-38	159.0	COG0003@1|root,COG0003@2|Bacteria,1PMWP@1224|Proteobacteria,42RUR@68525|delta/epsilon subdivisions,2WNEE@28221|Deltaproteobacteria,2YUU4@29|Myxococcales	28221|Deltaproteobacteria	D	AAA domain	agmR	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
TLS3_k127_1058851_2	404589.Anae109_3223	1.198e-159	520.0	COG0451@1|root,COG0451@2|Bacteria,1Q4V9@1224|Proteobacteria,42YHQ@68525|delta/epsilon subdivisions,2WUA6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_cc
TLS3_k127_1058851_3	404589.Anae109_3222	1.871e-124	406.0	COG2227@1|root,COG2227@2|Bacteria,1NN3B@1224|Proteobacteria,43C3V@68525|delta/epsilon subdivisions,2X7MU@28221|Deltaproteobacteria,2YWQK@29|Myxococcales	28221|Deltaproteobacteria	H	Protein of unknown function (DUF1698)	-	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
TLS3_k127_1058851_0	483219.LILAB_00535	1.204e-223	707.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,43C63@68525|delta/epsilon subdivisions,2WTQK@28221|Deltaproteobacteria,2YXI2@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter transmembrane region	msbA9	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS3_k127_1058851_1	404589.Anae109_3221	1.901e-163	529.0	COG4641@1|root,COG4641@2|Bacteria,1MY6E@1224|Proteobacteria,42YKD@68525|delta/epsilon subdivisions,2WU5I@28221|Deltaproteobacteria,2YUP6@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
TLS3_k127_1058851_4	1123368.AUIS01000005_gene422	1.289e-106	366.0	COG0438@1|root,COG0438@2|Bacteria,1Q3IF@1224|Proteobacteria	1224|Proteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_1058851_5	404589.Anae109_3219	8.985e-88	292.0	COG0673@1|root,COG0673@2|Bacteria,1NKUI@1224|Proteobacteria,43A3J@68525|delta/epsilon subdivisions,2WTZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_1087596_9	404589.Anae109_1735	1.621e-60	218.0	COG0457@1|root,COG3629@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria	1224|Proteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_16,TPR_8,Trans_reg_C
TLS3_k127_1087596_5	404589.Anae109_1736	1.323e-177	568.0	COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria	1224|Proteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1087596_3	404589.Anae109_0476	1.541e-182	576.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,42M3V@68525|delta/epsilon subdivisions,2WJJ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
TLS3_k127_1087596_7	404589.Anae109_0475	3.206e-114	379.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
TLS3_k127_1087596_6	404589.Anae109_0473	5.335e-171	540.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria,2YUI6@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin
TLS3_k127_1087596_14	369723.Strop_4549	6.397e-08	65.0	2ATXZ@1|root,31JHI@2|Bacteria,2GN21@201174|Actinobacteria,4D910@85008|Micromonosporales	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
TLS3_k127_1087596_8	290397.Adeh_3953	8.838e-78	290.0	COG1099@1|root,COG1099@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
TLS3_k127_1087596_1	404589.Anae109_0464	1.113e-215	682.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,42NY8@68525|delta/epsilon subdivisions,2WJNT@28221|Deltaproteobacteria,2YU0V@29|Myxococcales	28221|Deltaproteobacteria	M	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
TLS3_k127_1087596_4	290397.Adeh_3958	1.457e-179	606.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,42N3K@68525|delta/epsilon subdivisions,2WIMV@28221|Deltaproteobacteria,2YTY5@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
TLS3_k127_1087596_0	404589.Anae109_0462	0.0	1037.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,2YU49@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
TLS3_k127_1087596_11	290397.Adeh_3960	1.564e-57	228.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,42TMM@68525|delta/epsilon subdivisions,2WQ6S@28221|Deltaproteobacteria,2YVZ3@29|Myxococcales	28221|Deltaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
TLS3_k127_1087596_13	1298864.AUEQ01000001_gene4733	9.762e-31	134.0	COG0664@1|root,COG0664@2|Bacteria,2IF4P@201174|Actinobacteria,237B5@1762|Mycobacteriaceae	201174|Actinobacteria	T	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_20
TLS3_k127_1087596_2	290397.Adeh_3964	3.504e-194	612.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,2YTSX@29|Myxococcales	28221|Deltaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
TLS3_k127_1087596_10	404589.Anae109_0455	4.657e-59	222.0	COG2979@1|root,COG2979@2|Bacteria	2|Bacteria	T	Protein of unknown function (DUF533)	-	-	-	ko:K11962	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	LETM1,TerB
TLS3_k127_1087596_12	861299.J421_3873	3.388e-32	128.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_1099786_6	246197.MXAN_5665	3.956e-50	197.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2WK1X@28221|Deltaproteobacteria,2YURN@29|Myxococcales	28221|Deltaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TLS3_k127_1099786_2	1242864.D187_006463	8.924e-132	427.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YUJY@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TLS3_k127_1099786_4	404589.Anae109_3911	2.914e-107	364.0	COG0428@1|root,COG0428@2|Bacteria,1RF7H@1224|Proteobacteria,42Y2I@68525|delta/epsilon subdivisions,2WSUS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
TLS3_k127_1099786_7	404589.Anae109_3910	3.349e-32	142.0	COG2901@1|root,COG2901@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	fis	GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03557,ko:K07712	ko02020,ko05111,map02020,map05111	M00497	-	-	ko00000,ko00001,ko00002,ko02022,ko03000,ko03036,ko03400	-	-	-	HTH_8
TLS3_k127_1099786_0	404589.Anae109_3909	2.286e-162	530.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2WKM7@28221|Deltaproteobacteria,2YVBI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	nifR3	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
TLS3_k127_1099786_1	290397.Adeh_3789	1.995e-157	516.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,2YURT@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
TLS3_k127_1099786_8	290397.Adeh_1425	2.069e-05	51.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
TLS3_k127_1099786_5	1267535.KB906767_gene2778	9.776e-53	194.0	COG1595@1|root,COG1595@2|Bacteria,3Y7S5@57723|Acidobacteria,2JMWY@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_1099786_3	290397.Adeh_3788	3.226e-117	386.0	COG0577@1|root,COG0577@2|Bacteria,1QXV8@1224|Proteobacteria,43C7Z@68525|delta/epsilon subdivisions,2X7IB@28221|Deltaproteobacteria,2YUZK@29|Myxococcales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
TLS3_k127_1139072_1	404589.Anae109_0271	1.642e-241	756.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,2YU6I@29|Myxococcales	28221|Deltaproteobacteria	I	Carboxyl transferase domain	pccB	-	2.1.3.1,2.1.3.15,6.4.1.3	ko:K01966,ko:K17489	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R00353,R01859	RC00040,RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
TLS3_k127_1139072_9	404589.Anae109_0273	5.252e-35	133.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
TLS3_k127_1139072_5	404589.Anae109_0274	4.027e-162	518.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,43AEV@68525|delta/epsilon subdivisions,2X5YA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	2-nitropropane dioxygenase	-	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
TLS3_k127_1139072_3	290397.Adeh_0254	2.24e-190	605.0	COG0707@1|root,COG0707@2|Bacteria	2|Bacteria	M	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	-	-	-	ko:K12583	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_tran_28_C,Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_1139072_6	404589.Anae109_0276	8.981e-91	333.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42QIX@68525|delta/epsilon subdivisions,2WJHE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TLS3_k127_1139072_4	290397.Adeh_2960	1.213e-177	564.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria,2YUM4@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
TLS3_k127_1139072_7	404589.Anae109_0278	1.112e-88	307.0	COG0642@1|root,COG2205@2|Bacteria,1R964@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg,RsbRD_N
TLS3_k127_1139072_2	404589.Anae109_0279	4.06e-213	674.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2YUGB@29|Myxococcales	28221|Deltaproteobacteria	I	Biotin carboxylase C-terminal domain	pccA	-	6.3.4.14,6.3.4.6,6.4.1.2	ko:K01941,ko:K01961	ko00061,ko00220,ko00620,ko00640,ko00720,ko00791,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00220,map00620,map00640,map00720,map00791,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R00774,R04385	RC00040,RC00253,RC00367,RC00378	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
TLS3_k127_1139072_0	404589.Anae109_0281	1.897e-296	940.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria,2YUA4@29|Myxococcales	28221|Deltaproteobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
TLS3_k127_1139072_8	290397.Adeh_0260	1.106e-65	239.0	COG0457@1|root,COG0484@1|root,COG0457@2|Bacteria,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,TPR_16
TLS3_k127_1153711_2	1123278.KB893586_gene524	4.527e-25	115.0	COG1595@1|root,COG1595@2|Bacteria,4NK4D@976|Bacteroidetes,47Q32@768503|Cytophagia	976|Bacteroidetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
TLS3_k127_1153711_4	215803.DB30_3071	1.05e-06	62.0	COG3227@1|root,COG4733@1|root,COG3227@2|Bacteria,COG4733@2|Bacteria,1NNV4@1224|Proteobacteria,42Q3S@68525|delta/epsilon subdivisions,2WYNH@28221|Deltaproteobacteria,2YZIM@29|Myxococcales	28221|Deltaproteobacteria	E	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1153711_1	1123278.KB893387_gene4337	7.192e-50	202.0	COG2755@1|root,COG3391@1|root,COG2755@2|Bacteria,COG3391@2|Bacteria,4PI0M@976|Bacteroidetes,47R8B@768503|Cytophagia	976|Bacteroidetes	E	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS3_k127_1153711_0	243231.GSU1000	3.224e-154	502.0	28HIY@1|root,2Z7U8@2|Bacteria,1MY3K@1224|Proteobacteria,42QIR@68525|delta/epsilon subdivisions,2WME0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1214769_1	404589.Anae109_1390	1.485e-125	422.0	COG0696@1|root,COG0696@2|Bacteria	2|Bacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme
TLS3_k127_1214769_2	404589.Anae109_1572	8.767e-123	408.0	COG3842@1|root,COG3842@2|Bacteria,1RC3N@1224|Proteobacteria,43AKP@68525|delta/epsilon subdivisions,2X60N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC transporter	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
TLS3_k127_1214769_5	290397.Adeh_0999	2.686e-94	313.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,42NZV@68525|delta/epsilon subdivisions,2WNTH@28221|Deltaproteobacteria,2YVIC@29|Myxococcales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
TLS3_k127_1214769_6	290397.Adeh_1000	4.067e-66	238.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,42QWE@68525|delta/epsilon subdivisions,2WQ82@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM molybdenum ABC transporter, periplasmic	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
TLS3_k127_1214769_7	290397.Adeh_0319	2.137e-55	208.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
TLS3_k127_1214769_3	404589.Anae109_1575	1.825e-99	332.0	COG1910@1|root,COG1910@2|Bacteria,1MVS4@1224|Proteobacteria,42NF7@68525|delta/epsilon subdivisions,2WJA9@28221|Deltaproteobacteria,2YW0W@29|Myxococcales	28221|Deltaproteobacteria	L	PBP superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,PBP_like
TLS3_k127_1214769_4	404589.Anae109_3639	1.039e-94	314.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions,2WPAC@28221|Deltaproteobacteria,2YW13@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_1214769_0	404589.Anae109_1393	1.145e-165	528.0	COG0312@1|root,COG0312@2|Bacteria,1Q3C0@1224|Proteobacteria,4393A@68525|delta/epsilon subdivisions,2X495@28221|Deltaproteobacteria,2YYIX@29|Myxococcales	28221|Deltaproteobacteria	S	peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
TLS3_k127_1230281_6	404589.Anae109_1507	1.501e-79	273.0	COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,42SHG@68525|delta/epsilon subdivisions,2WP1D@28221|Deltaproteobacteria,2YWS7@29|Myxococcales	28221|Deltaproteobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
TLS3_k127_1230281_4	290397.Adeh_2363	5.68e-111	375.0	COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,42PZY@68525|delta/epsilon subdivisions,2WJ9V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit	scoB	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
TLS3_k127_1230281_5	404589.Anae109_1505	4.639e-107	365.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,42QMC@68525|delta/epsilon subdivisions,2WMDH@28221|Deltaproteobacteria,2YU4I@29|Myxococcales	28221|Deltaproteobacteria	I	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	scoA	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
TLS3_k127_1230281_0	404589.Anae109_1504	2.036e-198	624.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2YUF5@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	bamN	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
TLS3_k127_1230281_3	404589.Anae109_1503	2.778e-133	432.0	COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,42NRH@68525|delta/epsilon subdivisions,2WNIB@28221|Deltaproteobacteria,2YV7G@29|Myxococcales	28221|Deltaproteobacteria	E	Asparaginase	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
TLS3_k127_1230281_1	404589.Anae109_2940	5.252e-165	533.0	2C6CZ@1|root,32R7W@2|Bacteria,1RH5F@1224|Proteobacteria,42NQC@68525|delta/epsilon subdivisions,2WMFH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2868)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2868
TLS3_k127_1230281_2	404589.Anae109_2941	5.808e-164	548.0	COG1159@1|root,COG1159@2|Bacteria,1QW17@1224|Proteobacteria,42MZH@68525|delta/epsilon subdivisions,2WKAE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3482)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3482,MMR_HSR1
TLS3_k127_1236878_1	404589.Anae109_0718	2.63e-172	547.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2WIPM@28221|Deltaproteobacteria,2YY2A@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
TLS3_k127_1236878_5	404589.Anae109_0717	2.587e-63	240.0	COG0546@1|root,COG0546@2|Bacteria,1P1EG@1224|Proteobacteria,431YQ@68525|delta/epsilon subdivisions,2WWM2@28221|Deltaproteobacteria,2Z34R@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
TLS3_k127_1236878_4	290397.Adeh_0671	1.2e-63	228.0	COG1670@1|root,COG1670@2|Bacteria,1NNMC@1224|Proteobacteria,43B06@68525|delta/epsilon subdivisions,2X6EA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1236878_0	404589.Anae109_0714	2.999e-239	749.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,42MS6@68525|delta/epsilon subdivisions,2WIYE@28221|Deltaproteobacteria,2YUMA@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
TLS3_k127_1236878_2	404589.Anae109_0713	4.634e-119	409.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,2YZGM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
TLS3_k127_1236878_3	290397.Adeh_0668	8.7e-98	329.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,42N32@68525|delta/epsilon subdivisions,2WKBN@28221|Deltaproteobacteria,2Z2I5@29|Myxococcales	28221|Deltaproteobacteria	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3
TLS3_k127_1245154_0	765420.OSCT_2615	0.0	1080.0	COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi,37711@32061|Chloroflexia	32061|Chloroflexia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
TLS3_k127_1245154_1	290397.Adeh_0870	1.097e-182	584.0	COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,42MWU@68525|delta/epsilon subdivisions,2WKCW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
TLS3_k127_1245154_2	314278.NB231_12104	4.363e-114	374.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	dioxygenase	ygiD	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046566,GO:0051213,GO:0055114	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
TLS3_k127_1245154_5	290397.Adeh_0497	1.376e-61	226.0	COG0864@1|root,COG0864@2|Bacteria,1RK4R@1224|Proteobacteria,42SID@68525|delta/epsilon subdivisions,2WQ86@28221|Deltaproteobacteria,2YW5X@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	nikR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
TLS3_k127_1245154_3	290397.Adeh_0493	9.128e-101	343.0	COG1122@1|root,COG1122@2|Bacteria,1N5X0@1224|Proteobacteria,43ADF@68525|delta/epsilon subdivisions,2WMEV@28221|Deltaproteobacteria,2Z0AP@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K02006,ko:K16787	ko02010,map02010	M00245,M00246,M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
TLS3_k127_1245154_4	404589.Anae109_2305	4.891e-85	307.0	COG0310@1|root,COG0310@2|Bacteria,1NTQK@1224|Proteobacteria,42REN@68525|delta/epsilon subdivisions,2X6GP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Cobalt uptake substrate-specific transmembrane region	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
TLS3_k127_1245154_6	932678.THERU_04830	1.758e-60	229.0	28N7F@1|root,2ZBC4@2|Bacteria,2G4MS@200783|Aquificae	200783|Aquificae	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
TLS3_k127_1245154_8	290397.Adeh_0496	2.382e-34	143.0	COG5266@1|root,COG5266@2|Bacteria,1NAWR@1224|Proteobacteria,42W0H@68525|delta/epsilon subdivisions,2WRKH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Nickel transport complex, NikM subunit, transmembrane	-	-	-	ko:K16915	ko02010,map02010	M00246	-	-	ko00000,ko00001,ko00002,ko02000	-	-	-	-
TLS3_k127_1245154_10	1122135.KB893167_gene2317	5.257e-13	75.0	COG5266@1|root,COG5266@2|Bacteria,1RGKP@1224|Proteobacteria,2U8CG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Domain of unknown function (DUF4198)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4198
TLS3_k127_1292646_3	404589.Anae109_0349	5.766e-63	216.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,42URG@68525|delta/epsilon subdivisions,2WNDG@28221|Deltaproteobacteria,2YVX9@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase-like domain	mceE	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
TLS3_k127_1292646_0	404589.Anae109_0348	6.751e-145	476.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
TLS3_k127_1292646_1	404589.Anae109_0347	1.42e-72	253.0	COG2715@1|root,COG2715@2|Bacteria,1QVA6@1224|Proteobacteria,42TBA@68525|delta/epsilon subdivisions,2WPCY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Nucleoside recognition	-	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
TLS3_k127_1292646_2	290397.Adeh_4077	6.694e-64	233.0	COG0700@1|root,COG0700@2|Bacteria,1MVZ0@1224|Proteobacteria,430SU@68525|delta/epsilon subdivisions,2WVYK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane protein required for spore maturation in B.subtilis	-	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	-
TLS3_k127_1292646_4	404589.Anae109_2962	3.281e-32	125.0	COG1396@1|root,COG3800@1|root,COG1396@2|Bacteria,COG3800@2|Bacteria,1MU50@1224|Proteobacteria,43B2B@68525|delta/epsilon subdivisions,2X6GC@28221|Deltaproteobacteria,2Z3AZ@29|Myxococcales	28221|Deltaproteobacteria	K	Pfam:DUF955	-	-	-	ko:K07110	-	-	-	-	ko00000,ko03000	-	-	-	DUF2083,HTH_3,HTH_31,Peptidase_M78
TLS3_k127_1322027_10	1048834.TC41_2756	7.493e-10	62.0	COG1853@1|root,COG1853@2|Bacteria,1V1X6@1239|Firmicutes,4HGJ2@91061|Bacilli	91061|Bacilli	S	PFAM flavin reductase domain protein FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
TLS3_k127_1322027_4	404589.Anae109_1034	3.631e-60	211.0	COG1853@1|root,COG1853@2|Bacteria	2|Bacteria	S	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
TLS3_k127_1322027_3	1265505.ATUG01000002_gene1325	1.395e-96	353.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y50@68525|delta/epsilon subdivisions,2WUBF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HTH_8,PAS_4,Sigma54_activat
TLS3_k127_1322027_8	483219.LILAB_09825	5.541e-23	113.0	COG3047@1|root,COG3047@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_1322027_6	644966.Tmar_0336	2.477e-35	147.0	COG0500@1|root,COG1547@1|root,COG1547@2|Bacteria,COG2226@2|Bacteria,1V45D@1239|Firmicutes	1239|Firmicutes	Q	SAM-dependent methyltransferase	ubiE7	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_1322027_2	404589.Anae109_2053	1.014e-105	346.0	COG0560@1|root,COG0560@2|Bacteria,1MZPG@1224|Proteobacteria,42Q82@68525|delta/epsilon subdivisions,2WMBU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	-	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD
TLS3_k127_1322027_7	290397.Adeh_2930	9.187e-30	126.0	2EC42@1|root,3362Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1322027_0	404589.Anae109_1667	4.992e-175	565.0	COG0476@1|root,COG1310@1|root,COG0476@2|Bacteria,COG1310@2|Bacteria,1R87S@1224|Proteobacteria,42R16@68525|delta/epsilon subdivisions,2WNMW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	2.7.7.73	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Prok-JAB,ThiF,ThiS-like
TLS3_k127_1322027_1	404589.Anae109_3084	4.019e-138	461.0	2C6TZ@1|root,32RHS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1322027_5	402881.Plav_3303	5.988e-50	197.0	COG1835@1|root,COG1835@2|Bacteria,1REU1@1224|Proteobacteria,2UBRE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS3_k127_1322027_9	404589.Anae109_3640	5.147e-17	81.0	COG0583@1|root,COG0583@2|Bacteria,1RE3B@1224|Proteobacteria,42Q4S@68525|delta/epsilon subdivisions,2WJQD@28221|Deltaproteobacteria,2YUXE@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS3_k127_1330003_0	290397.Adeh_0953	2.747e-148	471.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria,2YUGW@29|Myxococcales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
TLS3_k127_1330003_4	404589.Anae109_1000	9.548e-76	261.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2Z1ZP@29|Myxococcales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	DnaJ_C,Rhomboid
TLS3_k127_1330003_1	404589.Anae109_1001	3.185e-136	439.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2WJ4I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535,ko:K13599	ko00540,ko01100,ko02020,map00540,map01100,map02020	M00060,M00498	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005,ko02022	-	-	-	LpxC
TLS3_k127_1330003_7	404589.Anae109_3563	7.393e-19	86.0	2EFZF@1|root,339RM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1330003_3	404589.Anae109_1008	7.864e-102	339.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,42RD5@68525|delta/epsilon subdivisions,2WMZ1@28221|Deltaproteobacteria,2YV5B@29|Myxococcales	28221|Deltaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
TLS3_k127_1330003_2	404589.Anae109_1007	2.203e-134	437.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42Z1A@68525|delta/epsilon subdivisions,2WU2C@28221|Deltaproteobacteria,2Z0AD@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
TLS3_k127_1335022_0	404589.Anae109_0780	0.0	1480.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2YU97@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
TLS3_k127_1335022_3	290397.Adeh_0734	2.161e-140	453.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2YWSU@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_1335022_5	290397.Adeh_0733	4.767e-102	340.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WP2A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
TLS3_k127_1335022_2	404589.Anae109_0776	4.218e-210	669.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria,2YTSW@29|Myxococcales	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
TLS3_k127_1335022_4	404589.Anae109_0775	1.125e-119	391.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,2YUYM@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
TLS3_k127_1335022_1	404589.Anae109_0774	5.9e-223	713.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,2YU66@29|Myxococcales	28221|Deltaproteobacteria	L	AAA C-terminal domain	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
TLS3_k127_1335022_6	290397.Adeh_0729	5.572e-67	253.0	COG1073@1|root,COG1073@2|Bacteria,1PBV5@1224|Proteobacteria,433TK@68525|delta/epsilon subdivisions,2X3EJ@28221|Deltaproteobacteria,2YVQG@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised protein family (UPF0227)	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
TLS3_k127_1393554_2	246197.MXAN_7084	2.764e-72	246.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
TLS3_k127_1393554_0	290397.Adeh_3715	9.054e-312	980.0	COG3408@1|root,COG3408@2|Bacteria,1MW01@1224|Proteobacteria,42NSN@68525|delta/epsilon subdivisions,2WJF7@28221|Deltaproteobacteria,2YX9T@29|Myxococcales	28221|Deltaproteobacteria	G	High confidence in function and specificity	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
TLS3_k127_1393554_1	290397.Adeh_3716	3.645e-96	321.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,42MKI@68525|delta/epsilon subdivisions,2WM5H@28221|Deltaproteobacteria,2YZJV@29|Myxococcales	28221|Deltaproteobacteria	G	Domain of unknown function (DUF3459)	treZ-2	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
TLS3_k127_1422747_5	1235457.C404_18170	1.449e-20	103.0	COG1246@1|root,COG1246@2|Bacteria,1NBIV@1224|Proteobacteria,2VX0R@28216|Betaproteobacteria,1KFHE@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7
TLS3_k127_1422747_4	404589.Anae109_3642	1.255e-24	115.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42RQI@68525|delta/epsilon subdivisions,2WNEC@28221|Deltaproteobacteria,2YUZQ@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
TLS3_k127_1422747_0	404589.Anae109_1612	1.773e-127	419.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,2YW96@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
TLS3_k127_1422747_2	404589.Anae109_1618	1.741e-112	384.0	COG1682@1|root,COG1682@2|Bacteria,1QXTH@1224|Proteobacteria,42XN1@68525|delta/epsilon subdivisions,2WSPR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
TLS3_k127_1422747_1	404589.Anae109_1617	1.928e-113	378.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42ZGK@68525|delta/epsilon subdivisions,2WUTG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_1422747_3	404589.Anae109_0559	5.864e-41	154.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
TLS3_k127_1461697_5	404589.Anae109_1412	2.132e-25	112.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
TLS3_k127_1461697_4	1128421.JAGA01000002_gene1178	2.386e-42	169.0	COG1216@1|root,COG1216@2|Bacteria,2NPYM@2323|unclassified Bacteria	2|Bacteria	L	Glycosyltransferase like family 2	wbbL_2	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_1461697_2	882083.SacmaDRAFT_0909	1.372e-58	229.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4DXK5@85010|Pseudonocardiales	201174|Actinobacteria	M	glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
TLS3_k127_1461697_0	404589.Anae109_1406	9.717e-125	419.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,42NNW@68525|delta/epsilon subdivisions,2WMWA@28221|Deltaproteobacteria,2YVKG@29|Myxococcales	28221|Deltaproteobacteria	GM	ABC transporter	-	-	3.6.3.38	ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
TLS3_k127_1461697_1	404589.Anae109_1405	3.517e-93	321.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,42QP4@68525|delta/epsilon subdivisions,2X5JM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
TLS3_k127_1461697_3	1144275.COCOR_04814	1.103e-47	177.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,42MGE@68525|delta/epsilon subdivisions,2WJC2@28221|Deltaproteobacteria,2YW3A@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
TLS3_k127_1472070_1	404589.Anae109_2356	9.001e-120	408.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2X7XX@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
TLS3_k127_1472070_2	485913.Krac_3074	5.534e-97	333.0	COG0665@1|root,COG0665@2|Bacteria,2G6XM@200795|Chloroflexi	200795|Chloroflexi	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00301	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
TLS3_k127_1472070_4	404589.Anae109_3497	1.317e-41	157.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,42TQH@68525|delta/epsilon subdivisions,2WQ2M@28221|Deltaproteobacteria,2Z1K8@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
TLS3_k127_1472070_0	1278073.MYSTI_05583	1.04e-133	438.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,42NR8@68525|delta/epsilon subdivisions,2WM9T@28221|Deltaproteobacteria,2Z05D@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_1556583_1	589865.DaAHT2_0407	4.118e-76	279.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_1556583_2	1121918.ARWE01000001_gene1125	4.965e-67	249.0	COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,42NE2@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9
TLS3_k127_1556583_3	237368.SCABRO_02784	3.099e-38	147.0	COG0822@1|root,COG0822@2|Bacteria,2J0AN@203682|Planctomycetes	203682|Planctomycetes	C	NifU-like N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
TLS3_k127_1556583_4	443144.GM21_3625	3.631e-32	131.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,42MCS@68525|delta/epsilon subdivisions,2WQGI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
TLS3_k127_1556583_0	1121918.ARWE01000001_gene2107	2.709e-123	410.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42M5U@68525|delta/epsilon subdivisions,2WJ06@28221|Deltaproteobacteria,43W0W@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
TLS3_k127_1597530_1	290397.Adeh_1482	2.423e-167	531.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria,2YUTU@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
TLS3_k127_1597530_2	290397.Adeh_1481	1.827e-146	477.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,439TT@68525|delta/epsilon subdivisions,2X575@28221|Deltaproteobacteria,2Z07H@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
TLS3_k127_1597530_3	290397.Adeh_1480	8.187e-137	449.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42NZ5@68525|delta/epsilon subdivisions,2X6U7@28221|Deltaproteobacteria,2Z3CS@29|Myxococcales	28221|Deltaproteobacteria	H	tRNA nucleotidyltransferase domain 2 putative	-	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
TLS3_k127_1597530_0	290397.Adeh_1659	2.011e-187	602.0	COG3005@1|root,COG3005@2|Bacteria,1R956@1224|Proteobacteria,42Q0X@68525|delta/epsilon subdivisions,2WMHI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
TLS3_k127_1597530_7	1121405.dsmv_0806	3.057e-19	97.0	2F35T@1|root,33W0F@2|Bacteria,1NVX1@1224|Proteobacteria,42ZTR@68525|delta/epsilon subdivisions,2WVA2@28221|Deltaproteobacteria,2MNJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_1597530_6	1449976.KALB_1205	7.216e-30	139.0	COG0300@1|root,COG0300@2|Bacteria,2I2VP@201174|Actinobacteria,4EDVR@85010|Pseudonocardiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_1597530_4	443143.GM18_2752	3.841e-135	447.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF1	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_1597530_5	404589.Anae109_0446	2.963e-95	334.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
TLS3_k127_1616633_10	404589.Anae109_2900	6.011e-50	194.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
TLS3_k127_1616633_2	404589.Anae109_2687	7.759e-227	710.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2WISV@28221|Deltaproteobacteria,2YWEJ@29|Myxococcales	28221|Deltaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
TLS3_k127_1616633_8	404589.Anae109_2688	3.998e-93	310.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,42MEH@68525|delta/epsilon subdivisions,2WMSC@28221|Deltaproteobacteria,2YUZC@29|Myxococcales	28221|Deltaproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
TLS3_k127_1616633_3	404589.Anae109_2689	8.986e-136	438.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,2YV00@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
TLS3_k127_1616633_9	290397.Adeh_2696	9.111e-92	336.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	aglU	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C,WD40
TLS3_k127_1616633_1	404589.Anae109_2691	2.264e-229	716.0	COG1206@1|root,COG1206@2|Bacteria,1MWNQ@1224|Proteobacteria,42MTS@68525|delta/epsilon subdivisions,2WJ50@28221|Deltaproteobacteria,2YU50@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
TLS3_k127_1616633_11	290397.Adeh_2698	5.708e-41	159.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
TLS3_k127_1616633_0	290397.Adeh_2699	0.0	1244.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2YU14@29|Myxococcales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
TLS3_k127_1616633_7	290397.Adeh_2700	7.124e-94	316.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,2YVFF@29|Myxococcales	28221|Deltaproteobacteria	LU	DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
TLS3_k127_1616633_5	404589.Anae109_2695	9.125e-111	381.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,42TT7@68525|delta/epsilon subdivisions,2WQR1@28221|Deltaproteobacteria,2Z2YV@29|Myxococcales	28221|Deltaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
TLS3_k127_1616633_6	290397.Adeh_2703	7.615e-97	322.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2WMQE@28221|Deltaproteobacteria,2YVJ7@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
TLS3_k127_1616633_4	290397.Adeh_2704	5.089e-133	441.0	COG2199@1|root,COG3850@1|root,COG2199@2|Bacteria,COG3850@2|Bacteria,1QTZT@1224|Proteobacteria,43E8E@68525|delta/epsilon subdivisions,2X7NE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
TLS3_k127_1616633_12	404589.Anae109_2699	6.992e-18	91.0	COG0745@1|root,COG1196@1|root,COG0745@2|Bacteria,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	Response_reg
TLS3_k127_1623184_7	404589.Anae109_3431	1.91e-33	135.0	COG2137@1|root,COG2137@2|Bacteria	2|Bacteria	S	regulation of DNA repair	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
TLS3_k127_1623184_2	404589.Anae109_3430	6.531e-90	312.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,42RV8@68525|delta/epsilon subdivisions,2WKU0@28221|Deltaproteobacteria,2YVHZ@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
TLS3_k127_1623184_5	404589.Anae109_3428	2.218e-63	226.0	COG0457@1|root,COG0457@2|Bacteria,1N5BD@1224|Proteobacteria,42U63@68525|delta/epsilon subdivisions,2WQUR@28221|Deltaproteobacteria,2YUQA@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
TLS3_k127_1623184_0	404589.Anae109_3427	1.398e-145	467.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria,2YUW8@29|Myxococcales	28221|Deltaproteobacteria	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
TLS3_k127_1623184_4	404589.Anae109_3426	1.095e-77	275.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria,2Z13M@29|Myxococcales	28221|Deltaproteobacteria	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
TLS3_k127_1623184_1	404589.Anae109_3425	1.712e-113	370.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,42NEX@68525|delta/epsilon subdivisions,2WJ1Y@28221|Deltaproteobacteria,2YUXF@29|Myxococcales	28221|Deltaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
TLS3_k127_1623184_6	290397.Adeh_3360	7.162e-43	170.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2WK3E@28221|Deltaproteobacteria,2YVIB@29|Myxococcales	28221|Deltaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1875	Ham1p_like
TLS3_k127_1643327_3	404589.Anae109_3545	7.925e-16	78.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,42N0U@68525|delta/epsilon subdivisions,2WJH3@28221|Deltaproteobacteria,2YWGV@29|Myxococcales	28221|Deltaproteobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
TLS3_k127_1643327_1	1121920.AUAU01000008_gene1586	9.315e-123	406.0	COG0077@1|root,COG0077@2|Bacteria,3Y49H@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
TLS3_k127_1643327_0	404589.Anae109_1498	0.0	1056.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CC6@68525|delta/epsilon subdivisions,2X7N2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
TLS3_k127_1643327_2	1274374.CBLK010000024_gene2695	3.935e-20	95.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli,26RDD@186822|Paenibacillaceae	91061|Bacilli	T	PhoB family transcriptional regulator	ykoG	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_1672198_5	404589.Anae109_2780	3.763e-20	97.0	COG0354@1|root,COG0354@2|Bacteria,1QYGE@1224|Proteobacteria,43CCJ@68525|delta/epsilon subdivisions,2WYDB@28221|Deltaproteobacteria,2Z3H2@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
TLS3_k127_1672198_2	290397.Adeh_2849	2.304e-117	395.0	COG0697@1|root,COG0697@2|Bacteria,1PX5W@1224|Proteobacteria,42MGR@68525|delta/epsilon subdivisions,2X5KV@28221|Deltaproteobacteria,2YY40@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_1672198_1	404589.Anae109_2783	1.091e-140	456.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,42PNR@68525|delta/epsilon subdivisions,2WK3I@28221|Deltaproteobacteria,2YV9T@29|Myxococcales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF1730)	yjeS	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
TLS3_k127_1672198_0	290397.Adeh_2855	9.93e-150	476.0	COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,42PA8@68525|delta/epsilon subdivisions,2X7NH@28221|Deltaproteobacteria,2YU70@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
TLS3_k127_1672198_4	290397.Adeh_2856	2.332e-37	151.0	COG0558@1|root,COG0558@2|Bacteria,1N9TT@1224|Proteobacteria,42V2Q@68525|delta/epsilon subdivisions,2WRYY@28221|Deltaproteobacteria,2YWYE@29|Myxococcales	28221|Deltaproteobacteria	I	GtrA-like protein	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf,GtrA
TLS3_k127_1672198_3	404589.Anae109_2786	3.684e-54	193.0	COG1329@1|root,COG1329@2|Bacteria	2|Bacteria	K	CarD-like/TRCF domain	carD	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
TLS3_k127_1685413_5	290397.Adeh_1603	3.166e-08	65.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	transglycosylase	slt	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	iETEC_1333.ETEC_4747,iPC815.YPO0452	SLT,SLT_L
TLS3_k127_1685413_1	290397.Adeh_1604	4.408e-97	341.0	COG2340@1|root,COG2340@2|Bacteria,1REVB@1224|Proteobacteria,4386P@68525|delta/epsilon subdivisions,2X3GI@28221|Deltaproteobacteria,2YW01@29|Myxococcales	28221|Deltaproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
TLS3_k127_1685413_4	404589.Anae109_2207	1.433e-24	112.0	COG5512@1|root,COG5512@2|Bacteria	2|Bacteria	L	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
TLS3_k127_1685413_0	290397.Adeh_1606	2.841e-104	377.0	COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,42WNA@68525|delta/epsilon subdivisions,2WRKM@28221|Deltaproteobacteria,2YUJ7@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_1685413_2	290397.Adeh_1607	1.926e-69	259.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,42UKS@68525|delta/epsilon subdivisions,2WQV2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
TLS3_k127_1686015_4	196367.JNFG01000199_gene3178	4.055e-08	62.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,2VN0C@28216|Betaproteobacteria,1JZZE@119060|Burkholderiaceae	28216|Betaproteobacteria	D	PFAM lipopolysaccharide biosynthesis	epsG	-	2.7.10.1	ko:K08252,ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,CBP_BcsQ,CbiA,GNVR,ParA,Wzz
TLS3_k127_1686015_0	1242864.D187_000822	1.063e-186	607.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2WJEB@28221|Deltaproteobacteria,2YZJA@29|Myxococcales	28221|Deltaproteobacteria	GM	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
TLS3_k127_1686015_1	649638.Trad_0103	7.978e-114	381.0	COG2232@1|root,COG2232@2|Bacteria	2|Bacteria	V	ATP-grasp domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3,Epimerase,HAD_2
TLS3_k127_1686015_3	391625.PPSIR1_27953	9.317e-66	231.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42NH8@68525|delta/epsilon subdivisions,2WN9A@28221|Deltaproteobacteria,2Z2XN@29|Myxococcales	28221|Deltaproteobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
TLS3_k127_1686015_2	1121405.dsmv_3785	2.936e-98	335.0	COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,42NYR@68525|delta/epsilon subdivisions,2WJB1@28221|Deltaproteobacteria,2MM2E@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_1754016_7	215803.DB30_8324	5.721e-17	93.0	29Z4J@1|root,30M27@2|Bacteria,1Q3S3@1224|Proteobacteria,439K6@68525|delta/epsilon subdivisions,2X4WW@28221|Deltaproteobacteria,2YZRZ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1754016_4	1038860.AXAP01000021_gene5543	1.514e-76	270.0	COG1125@1|root,COG1125@2|Bacteria,1RF8Y@1224|Proteobacteria,2U8WZ@28211|Alphaproteobacteria,3JZ00@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
TLS3_k127_1754016_5	240015.ACP_3003	6.165e-57	209.0	COG0390@1|root,COG0390@2|Bacteria,3Y7K5@57723|Acidobacteria,2JMW7@204432|Acidobacteriia	204432|Acidobacteriia	S	Uncharacterised protein family (UPF0014)	-	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
TLS3_k127_1754016_1	1210884.HG799466_gene12502	1.315e-135	456.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_1754016_2	290397.Adeh_2014	5.364e-133	434.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,42YH3@68525|delta/epsilon subdivisions,2WU01@28221|Deltaproteobacteria,2YYVS@29|Myxococcales	28221|Deltaproteobacteria	H	Coproporphyrinogen III oxidase	hemF	-	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
TLS3_k127_1754016_6	1463881.KL591021_gene881	1.292e-31	128.0	2EAYY@1|root,334ZV@2|Bacteria,2I2ZT@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
TLS3_k127_1754016_0	1300345.LF41_834	7.139e-176	601.0	COG1858@1|root,COG1858@2|Bacteria,1MWAT@1224|Proteobacteria,1RN8J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Di-haem cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
TLS3_k127_1754016_8	404589.Anae109_4480	3.859e-10	73.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
TLS3_k127_1754016_3	246197.MXAN_3419	3.119e-85	301.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,4301R@68525|delta/epsilon subdivisions,2WVCA@28221|Deltaproteobacteria,2YYZK@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_1771747_4	404589.Anae109_0191	7.796e-47	172.0	COG1163@1|root,COG1163@2|Bacteria,1RFPD@1224|Proteobacteria,42ZF3@68525|delta/epsilon subdivisions,2WUZY@28221|Deltaproteobacteria,2Z0K4@29|Myxococcales	28221|Deltaproteobacteria	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
TLS3_k127_1771747_5	583355.Caka_2946	2.202e-33	139.0	COG0139@1|root,COG0139@2|Bacteria,46SZA@74201|Verrucomicrobia,3K7YM@414999|Opitutae	414999|Opitutae	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
TLS3_k127_1771747_7	386456.JQKN01000002_gene2773	2.914e-24	117.0	COG0040@1|root,arCOG02208@2157|Archaea,2Y32G@28890|Euryarchaeota,23PBA@183925|Methanobacteria	183925|Methanobacteria	E	PFAM ATP phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HisG
TLS3_k127_1771747_0	555088.DealDRAFT_1835	1.266e-193	622.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,249HB@186801|Clostridia	186801|Clostridia	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_1771747_6	94624.Bpet3300	3.996e-31	132.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2VNPJ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
TLS3_k127_1771747_3	1380394.JADL01000002_gene1317	4.969e-51	195.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2UNXP@28211|Alphaproteobacteria,2JW50@204441|Rhodospirillales	204441|Rhodospirillales	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
TLS3_k127_1771747_1	290397.Adeh_3040	8.055e-134	432.0	COG0667@1|root,COG0667@2|Bacteria,1Q2VX@1224|Proteobacteria,438IJ@68525|delta/epsilon subdivisions,2X3TE@28221|Deltaproteobacteria,2YX2D@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_1771747_8	404589.Anae109_4250	1.062e-21	105.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
TLS3_k127_1773159_1	404589.Anae109_2703	1.792e-187	597.0	COG3408@1|root,COG3408@2|Bacteria,1MUYU@1224|Proteobacteria,42NE9@68525|delta/epsilon subdivisions,2WKU2@28221|Deltaproteobacteria,2YYXU@29|Myxococcales	28221|Deltaproteobacteria	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
TLS3_k127_1773159_4	404589.Anae109_2704	5.451e-107	360.0	COG0438@1|root,COG0438@2|Bacteria,1MWSZ@1224|Proteobacteria,42NYZ@68525|delta/epsilon subdivisions,2WK9U@28221|Deltaproteobacteria,2Z080@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,MannoseP_isomer
TLS3_k127_1773159_0	290397.Adeh_2714	5.721e-203	638.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2YXJE@29|Myxococcales	28221|Deltaproteobacteria	NU	twitching motility protein	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
TLS3_k127_1773159_5	290397.Adeh_2715	3.39e-105	353.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
TLS3_k127_1773159_3	404589.Anae109_2708	1.501e-154	494.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,42MKD@68525|delta/epsilon subdivisions,2WIZP@28221|Deltaproteobacteria,2YU17@29|Myxococcales	28221|Deltaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TLS3_k127_1773159_2	404589.Anae109_2709	2.488e-179	579.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,2YVAG@29|Myxococcales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
TLS3_k127_1792968_4	404589.Anae109_1013	9.601e-46	175.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,42XGR@68525|delta/epsilon subdivisions,2WSJF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
TLS3_k127_1792968_0	404589.Anae109_1760	4.136e-248	792.0	COG3033@1|root,COG3033@2|Bacteria,1NG5U@1224|Proteobacteria,42QJ3@68525|delta/epsilon subdivisions,2WKUT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Beta-eliminating lyase	-	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
TLS3_k127_1792968_3	404589.Anae109_1178	6.559e-49	181.0	2DC7W@1|root,2ZD7C@2|Bacteria,1QU8S@1224|Proteobacteria,42TNH@68525|delta/epsilon subdivisions,2WQ32@28221|Deltaproteobacteria,2YVZS@29|Myxococcales	28221|Deltaproteobacteria	S	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
TLS3_k127_1792968_5	1232410.KI421415_gene3082	1.413e-23	115.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Smr protein MutS2	-	-	-	-	-	-	-	-	-	-	-	-	Smr
TLS3_k127_1792968_1	1254432.SCE1572_01725	2.704e-126	415.0	COG0491@1|root,COG0491@2|Bacteria,1N1ZW@1224|Proteobacteria,42WXX@68525|delta/epsilon subdivisions,2WSQH@28221|Deltaproteobacteria,2YZ1U@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_1792968_2	518766.Rmar_1593	1.086e-88	306.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
TLS3_k127_1798256_7	443143.GM18_1505	1.42e-54	196.0	COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,42NK5@68525|delta/epsilon subdivisions,2WM49@28221|Deltaproteobacteria,43VZU@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PBP superfamily domain	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
TLS3_k127_1798256_4	56780.SYN_00844	3.491e-80	282.0	COG1910@1|root,COG1910@2|Bacteria,1MVS4@1224|Proteobacteria,42NF7@68525|delta/epsilon subdivisions,2WJA9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,PBP_like
TLS3_k127_1798256_3	404589.Anae109_3057	5.358e-93	311.0	COG1125@1|root,COG1125@2|Bacteria,1QTUC@1224|Proteobacteria,42MXW@68525|delta/epsilon subdivisions,2WK94@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM ABC transporter	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
TLS3_k127_1798256_1	404589.Anae109_3056	9.377e-181	581.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MXA1@1224|Proteobacteria,42UI3@68525|delta/epsilon subdivisions,2WQ1V@28221|Deltaproteobacteria,2YVFQ@29|Myxococcales	28221|Deltaproteobacteria	P	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
TLS3_k127_1798256_2	680198.SCAB_63371	1.702e-101	338.0	COG1878@1|root,COG1878@2|Bacteria,2I66K@201174|Actinobacteria	201174|Actinobacteria	S	PFAM cyclase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
TLS3_k127_1798256_8	290397.Adeh_1297	2.638e-41	170.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	slt	-	-	-	-	-	-	-	-	-	-	-	SLT
TLS3_k127_1798256_5	290397.Adeh_2901	2.661e-61	215.0	COG0662@1|root,COG0662@2|Bacteria,1N1T5@1224|Proteobacteria	1224|Proteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_1798256_0	448385.sce0471	6.789e-233	729.0	COG1414@1|root,COG1414@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	3.6.4.12	ko:K03655,ko:K10439,ko:K11708	ko02010,ko02030,ko03440,map02010,map02030,map03440	M00212,M00319	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko03400	3.A.1.15,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	AlbA_2,HATPase_c_4,HTH_IclR,IclR,Peripla_BP_4,VCBS
TLS3_k127_1812385_4	404589.Anae109_1984	2.491e-90	302.0	COG0392@1|root,COG0392@2|Bacteria,1PPSZ@1224|Proteobacteria,434R6@68525|delta/epsilon subdivisions,2WZ2B@28221|Deltaproteobacteria,2Z16A@29|Myxococcales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
TLS3_k127_1812385_9	290397.Adeh_1859	4.606e-22	97.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,42XRW@68525|delta/epsilon subdivisions,2X2JD@28221|Deltaproteobacteria,2YW45@29|Myxococcales	28221|Deltaproteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	-	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
TLS3_k127_1812385_8	290397.Adeh_1860	9.136e-48	177.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
TLS3_k127_1812385_0	404589.Anae109_1978	3.226e-170	549.0	COG1463@1|root,COG1463@2|Bacteria,1RFFS@1224|Proteobacteria,42P4P@68525|delta/epsilon subdivisions,2WNNQ@28221|Deltaproteobacteria,2YUZI@29|Myxococcales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
TLS3_k127_1812385_1	404589.Anae109_1977	6.505e-119	399.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran,GGDEF
TLS3_k127_1812385_2	404589.Anae109_1976	2.49e-103	341.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MR1@68525|delta/epsilon subdivisions,2WKC9@28221|Deltaproteobacteria,2YV04@29|Myxococcales	28221|Deltaproteobacteria	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
TLS3_k127_1812385_3	338963.Pcar_2234	1.815e-90	311.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2WIVG@28221|Deltaproteobacteria,43TGR@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
TLS3_k127_1812385_7	404589.Anae109_1975	2.335e-52	189.0	2E6J8@1|root,3316B@2|Bacteria,1N7GY@1224|Proteobacteria,42V6W@68525|delta/epsilon subdivisions,2WRHG@28221|Deltaproteobacteria,2YYZA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1812385_5	404589.Anae109_1974	4.757e-73	255.0	COG0564@1|root,COG0564@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	-	-	5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29	ko:K06177,ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2,S4
TLS3_k127_1812385_6	290397.Adeh_1866	1.086e-72	250.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2WR3G@28221|Deltaproteobacteria,2YXS5@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_182670_2	1408813.AYMG01000012_gene864	0.0001588	54.0	COG3652@1|root,COG3652@2|Bacteria,4NQE9@976|Bacteroidetes,1IYHK@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4142)	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
TLS3_k127_182670_0	298653.Franean1_6327	1.685e-107	359.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4ETQ1@85013|Frankiales	201174|Actinobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_182670_1	404589.Anae109_1681	1.35e-80	274.0	COG0667@1|root,COG0667@2|Bacteria,1MU1S@1224|Proteobacteria	1224|Proteobacteria	C	Aldo keto reductase	yghZ	GO:0003674,GO:0003824,GO:0006081,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0050896,GO:0051596,GO:0051716,GO:0055114,GO:0071704,GO:1901575	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	iSBO_1134.SBO_2995	Aldo_ket_red
TLS3_k127_1831132_9	215803.DB30_5377	4.045e-101	364.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,42Q8W@68525|delta/epsilon subdivisions,2WJVN@28221|Deltaproteobacteria,2YY2E@29|Myxococcales	28221|Deltaproteobacteria	EU	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
TLS3_k127_1831132_3	404589.Anae109_3834	3.276e-218	695.0	COG1055@1|root,COG1055@2|Bacteria,1MXKG@1224|Proteobacteria,42PAX@68525|delta/epsilon subdivisions,2WKEP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Putative citrate transport	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
TLS3_k127_1831132_14	404589.Anae109_3833	5.926e-32	129.0	COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,42VFF@68525|delta/epsilon subdivisions,2WR8E@28221|Deltaproteobacteria,2Z2T8@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
TLS3_k127_1831132_0	404589.Anae109_3832	3.575e-297	924.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42NJZ@68525|delta/epsilon subdivisions,2WK1Q@28221|Deltaproteobacteria,2YZK2@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
TLS3_k127_1831132_4	290397.Adeh_3695	1.626e-205	656.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2WJF5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	CBS domain containing protein	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
TLS3_k127_1831132_1	404589.Anae109_3824	1.667e-265	829.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2WJF5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	CBS domain containing protein	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
TLS3_k127_1831132_12	404589.Anae109_3823	4.684e-70	263.0	COG0847@1|root,COG0847@2|Bacteria,1RAF1@1224|Proteobacteria,42W6M@68525|delta/epsilon subdivisions,2WS2C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
TLS3_k127_1831132_10	765912.Thimo_1293	1.894e-81	283.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1WVWQ@135613|Chromatiales	135613|Chromatiales	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C
TLS3_k127_1831132_7	290397.Adeh_3731	1.902e-133	433.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,42NHN@68525|delta/epsilon subdivisions,2WJ4S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome d ubiquinol oxidase, subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
TLS3_k127_1831132_2	290397.Adeh_3730	1.384e-220	691.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,42MB8@68525|delta/epsilon subdivisions,2WIW7@28221|Deltaproteobacteria,2YU2P@29|Myxococcales	28221|Deltaproteobacteria	C	ubiquinol oxidase subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
TLS3_k127_1831132_11	290397.Adeh_3727	2.094e-80	289.0	COG1164@1|root,COG1164@2|Bacteria,1NZCR@1224|Proteobacteria,430YT@68525|delta/epsilon subdivisions,2WVYT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Oligoendopeptidase f	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1831132_6	290397.Adeh_3726	3.84e-137	470.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,42MAN@68525|delta/epsilon subdivisions,2WJBB@28221|Deltaproteobacteria,2YUT5@29|Myxococcales	28221|Deltaproteobacteria	J	tRNA synthetases class II (D, K and N)	genX	-	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
TLS3_k127_1831132_5	290397.Adeh_3722	1.877e-189	597.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,42M7K@68525|delta/epsilon subdivisions,2WKKM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
TLS3_k127_1831132_8	404589.Anae109_3849	5.636e-112	369.0	COG0491@1|root,COG0491@2|Bacteria,1R4FA@1224|Proteobacteria,43APW@68525|delta/epsilon subdivisions,2X63P@28221|Deltaproteobacteria,2Z38U@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_1834509_4	136273.GY22_04940	8.466e-51	189.0	COG0596@1|root,COG0596@2|Bacteria,2IDI0@201174|Actinobacteria,1WABF@1268|Micrococcaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
TLS3_k127_1834509_3	290397.Adeh_1153	2.674e-70	250.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,42QU8@68525|delta/epsilon subdivisions,2X5Q5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
TLS3_k127_1834509_0	443143.GM18_1507	2.757e-124	422.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42S6I@68525|delta/epsilon subdivisions,2WNNW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TOBE domain	-	-	3.6.3.29,3.6.3.55	ko:K02017,ko:K06857	ko02010,map02010	M00186,M00189	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4,3.A.1.8	-	-	ABC_tran,TOBE
TLS3_k127_1834509_1	443143.GM18_1506	5.429e-105	344.0	COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,42N6T@68525|delta/epsilon subdivisions,2WMKR@28221|Deltaproteobacteria,43S3K@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
TLS3_k127_1834509_2	443143.GM18_1505	2.186e-83	281.0	COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,42NK5@68525|delta/epsilon subdivisions,2WM49@28221|Deltaproteobacteria,43VZU@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PBP superfamily domain	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
TLS3_k127_1840139_1	290397.Adeh_3665	2.571e-126	410.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42M33@68525|delta/epsilon subdivisions,2WJGS@28221|Deltaproteobacteria,2YU96@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
TLS3_k127_1840139_5	1121946.AUAX01000004_gene741	1.073e-34	147.0	COG5542@1|root,COG5542@2|Bacteria,2HUA7@201174|Actinobacteria,4DDHD@85008|Micromonosporales	201174|Actinobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
TLS3_k127_1840139_2	1144275.COCOR_05434	6.477e-108	371.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1NRP8@1224|Proteobacteria,42T7K@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
TLS3_k127_1840139_4	743720.Psefu_0575	1.15e-46	177.0	COG2201@1|root,COG2201@2|Bacteria,1RCWE@1224|Proteobacteria,1S6II@1236|Gammaproteobacteria,1YYHV@136845|Pseudomonas putida group	1236|Gammaproteobacteria	NT	methylesterase	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
TLS3_k127_1840139_3	743721.Psesu_2898	5.929e-91	331.0	COG1352@1|root,COG1352@2|Bacteria,1NQTI@1224|Proteobacteria,1RS9Z@1236|Gammaproteobacteria,1X3G6@135614|Xanthomonadales	135614|Xanthomonadales	NT	chemotaxis	cheR1	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
TLS3_k127_1840139_0	1297742.A176_04574	4.665e-279	885.0	COG0745@1|root,COG2199@1|root,COG5002@1|root,COG5278@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria,1R7HC@1224|Proteobacteria,43BXB@68525|delta/epsilon subdivisions,2X784@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,Response_reg
TLS3_k127_1841378_12	1502851.FG93_03412	3.343e-58	224.0	COG3899@1|root,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria	1224|Proteobacteria	T	Adenylate Guanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE,Trans_reg_C
TLS3_k127_1841378_21	251229.Chro_3261	1.584e-09	62.0	2C1W2@1|root,31MWG@2|Bacteria,1G6PN@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
TLS3_k127_1841378_9	215803.DB30_1592	3.368e-93	317.0	COG0657@1|root,COG0657@2|Bacteria,1MVRE@1224|Proteobacteria,42XSE@68525|delta/epsilon subdivisions,2WTGG@28221|Deltaproteobacteria,2YYH0@29|Myxococcales	28221|Deltaproteobacteria	I	Pectinacetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	PAE
TLS3_k127_1841378_5	159087.Daro_1885	6.143e-131	431.0	COG2271@1|root,COG2271@2|Bacteria,1QU9E@1224|Proteobacteria,2WGJT@28216|Betaproteobacteria,2KU7W@206389|Rhodocyclales	206389|Rhodocyclales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_1841378_0	404589.Anae109_3725	0.0	1071.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M8C@68525|delta/epsilon subdivisions,2WJB3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02688	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,PrpR_N,Sigma54_activat
TLS3_k127_1841378_2	404589.Anae109_3724	1.207e-189	602.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2WJTS@28221|Deltaproteobacteria,2YU09@29|Myxococcales	28221|Deltaproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2261	ATP-grasp_2,Ligase_CoA
TLS3_k127_1841378_4	404589.Anae109_3723	1.068e-171	544.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria,2YTTU@29|Myxococcales	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,CoA_binding,Ligase_CoA
TLS3_k127_1841378_14	443143.GM18_2797	1.228e-47	189.0	COG1556@1|root,COG1556@2|Bacteria,1RCQZ@1224|Proteobacteria,42VWP@68525|delta/epsilon subdivisions,2X5IE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
TLS3_k127_1841378_1	404380.Gbem_2911	2.979e-303	951.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,42MN2@68525|delta/epsilon subdivisions,2WIMJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	cluster binding protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_7,Fer4_8,LUD_dom
TLS3_k127_1841378_17	365046.Rta_06450	1.082e-32	136.0	2DNNN@1|root,32YAU@2|Bacteria,1NA5K@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1841378_19	414684.RC1_0777	6.928e-17	94.0	2EZQR@1|root,33SVP@2|Bacteria,1NQXS@1224|Proteobacteria,2UQUK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1841378_22	1479237.JMLY01000001_gene1882	7.238e-07	51.0	28N6F@1|root,2ZBBB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1841378_6	357808.RoseRS_1116	1.862e-117	389.0	COG0530@1|root,COG0530@2|Bacteria,2G6GV@200795|Chloroflexi,376V8@32061|Chloroflexia	32061|Chloroflexia	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
TLS3_k127_1841378_20	287986.DV20_27885	4.33e-13	75.0	COG1238@1|root,COG1238@2|Bacteria,2GS5H@201174|Actinobacteria,4E40N@85010|Pseudonocardiales	201174|Actinobacteria	I	metal cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
TLS3_k127_1841378_18	1463821.JOGR01000013_gene3200	1.315e-32	136.0	COG0558@1|root,COG0558@2|Bacteria,2IMJZ@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
TLS3_k127_1841378_8	983920.Y88_2684	2.909e-96	326.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2TQQP@28211|Alphaproteobacteria,2K9GW@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
TLS3_k127_1841378_13	269799.Gmet_0908	1.606e-55	214.0	2B8GB@1|root,321RF@2|Bacteria,1RIVE@1224|Proteobacteria,42SWQ@68525|delta/epsilon subdivisions,2WPWX@28221|Deltaproteobacteria,43V4P@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1841378_15	243231.GSU2732	7.175e-46	173.0	COG3303@1|root,COG3303@2|Bacteria,1NKAH@1224|Proteobacteria,431V2@68525|delta/epsilon subdivisions,2WWRA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	8 heme-binding sites	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
TLS3_k127_1841378_11	706587.Desti_1939	1.615e-63	228.0	COG0437@1|root,COG0437@2|Bacteria,1MUIE@1224|Proteobacteria,42RCG@68525|delta/epsilon subdivisions,2WMYK@28221|Deltaproteobacteria,2MRC9@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
TLS3_k127_1841378_3	457570.Nther_2279	4.166e-178	584.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738,ko:K19515	ko00030,ko00362,ko01100,ko01120,ko01200,map00030,map00362,map01100,map01120,map01200	M00309,M00541	R08571,R10961	RC00242,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
TLS3_k127_1841378_16	404380.Gbem_2088	2.131e-43	169.0	28VFF@1|root,2ZHI0@2|Bacteria,1RBE4@1224|Proteobacteria	1224|Proteobacteria	-	-	ydhW	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1841378_10	269799.Gmet_2076	1.398e-91	309.0	COG1526@1|root,COG1526@2|Bacteria,1NRU0@1224|Proteobacteria,42PRH@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0043085,GO:0043546,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050790,GO:0065007,GO:0065009,GO:0097159,GO:0097163,GO:0140104,GO:1901363	-	ko:K02379,ko:K18360	ko00360,map00360	-	R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001	-	-	-	FdhD-NarQ
TLS3_k127_1841378_7	589865.DaAHT2_0407	1.66e-105	350.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_1906126_5	1168059.KB899087_gene3235	3.15e-05	50.0	COG0745@1|root,COG2199@1|root,COG4251@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,1R7HC@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,Response_reg
TLS3_k127_1906126_1	404589.Anae109_1949	4.583e-104	351.0	COG0454@1|root,COG2808@1|root,COG0456@2|Bacteria,COG2808@2|Bacteria,1QYFM@1224|Proteobacteria,43CBS@68525|delta/epsilon subdivisions,2X7MI@28221|Deltaproteobacteria,2Z3GT@29|Myxococcales	28221|Deltaproteobacteria	K	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
TLS3_k127_1906126_3	404589.Anae109_3789	1.681e-52	207.0	COG0500@1|root,COG2226@2|Bacteria,1NNI3@1224|Proteobacteria,4321D@68525|delta/epsilon subdivisions,2WX0S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_1906126_4	290397.Adeh_3661	1.227e-35	150.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
TLS3_k127_1906126_2	404589.Anae109_3779	8.269e-70	243.0	COG1762@1|root,COG1762@2|Bacteria,1RG0Z@1224|Proteobacteria,42RSF@68525|delta/epsilon subdivisions,2WNXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	HTH_17,PTS_EIIA_2
TLS3_k127_1906126_0	290397.Adeh_3654	1.002e-196	633.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,42NFV@68525|delta/epsilon subdivisions,2WJZ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
TLS3_k127_191023_0	404589.Anae109_2995	0.0	1351.0	COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,43BKE@68525|delta/epsilon subdivisions,2X6YE@28221|Deltaproteobacteria,2YYQ8@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
TLS3_k127_191023_1	404589.Anae109_2830	1.545e-172	550.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,430G4@68525|delta/epsilon subdivisions,2WVMP@28221|Deltaproteobacteria,2YZCC@29|Myxococcales	28221|Deltaproteobacteria	L	PFAM DNA primase small subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_191023_2	479434.Sthe_2990	1.294e-48	179.0	COG0252@1|root,COG0252@2|Bacteria,2G8JK@200795|Chloroflexi	200795|Chloroflexi	EJ	PFAM Asparaginase glutaminase	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
TLS3_k127_1917367_0	290397.Adeh_0812	1.049e-142	468.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTW0@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_1917367_1	290397.Adeh_0813	7.905e-110	392.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,43BH8@68525|delta/epsilon subdivisions,2X6VM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
TLS3_k127_1917367_2	290397.Adeh_0814	3.043e-93	324.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	resB	-	-	-	-	-	-	-	-	-	-	-	ResB
TLS3_k127_1933496_3	290397.Adeh_1370	1.368e-31	139.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2Z2WJ@29|Myxococcales	28221|Deltaproteobacteria	F	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
TLS3_k127_1933496_0	290397.Adeh_1368	7.659e-150	484.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1RDNP@1224|Proteobacteria,42RF8@68525|delta/epsilon subdivisions,2WNSP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
TLS3_k127_1933496_1	290397.Adeh_1367	3.943e-95	322.0	COG1639@1|root,COG1639@2|Bacteria,1N38F@1224|Proteobacteria,42UBF@68525|delta/epsilon subdivisions,2WQEF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Metal-dependent phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
TLS3_k127_1933496_4	526227.Mesil_3342	0.0001605	54.0	2DVHC@1|root,33VWJ@2|Bacteria,1WMN4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1961799_9	59538.XP_005979423.1	1.38e-05	49.0	COG0277@1|root,KOG1231@2759|Eukaryota,38FXH@33154|Opisthokonta,3BEEV@33208|Metazoa,3CRTP@33213|Bilateria,4801S@7711|Chordata,492UT@7742|Vertebrata,3JDRF@40674|Mammalia,4J43Y@91561|Cetartiodactyla	33208|Metazoa	C	dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_8
TLS3_k127_1961799_4	404589.Anae109_1088	5.581e-69	256.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,42RN4@68525|delta/epsilon subdivisions,2WP37@28221|Deltaproteobacteria,2YVD3@29|Myxococcales	28221|Deltaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
TLS3_k127_1961799_0	404589.Anae109_1089	4.477e-288	894.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,42NVI@68525|delta/epsilon subdivisions,2WJTD@28221|Deltaproteobacteria,2YTYS@29|Myxococcales	28221|Deltaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TLS3_k127_1961799_6	290397.Adeh_1041	2.76e-47	173.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,42U8W@68525|delta/epsilon subdivisions,2X3DV@28221|Deltaproteobacteria,2YVMF@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
TLS3_k127_1961799_8	404589.Anae109_1091	3.233e-34	132.0	COG1145@1|root,COG1145@2|Bacteria,1QUJB@1224|Proteobacteria,42TSI@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Ferredoxin	fdxA	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
TLS3_k127_1961799_3	404589.Anae109_1093	1.697e-88	302.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,42T4F@68525|delta/epsilon subdivisions,2WP6B@28221|Deltaproteobacteria,2YVEY@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
TLS3_k127_1961799_5	886293.Sinac_5471	3.062e-60	235.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
TLS3_k127_1961799_1	404589.Anae109_1094	1.048e-214	672.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,2YU10@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
TLS3_k127_1961799_2	404589.Anae109_1095	1.918e-128	415.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
TLS3_k127_1961799_7	404589.Anae109_1096	1.342e-44	170.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,42U47@68525|delta/epsilon subdivisions,2WQXE@28221|Deltaproteobacteria,2YVV5@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
TLS3_k127_1968545_10	290397.Adeh_1809	3.48e-33	133.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	-	-	-	ko:K13695	-	-	-	-	ko00000,ko01002	-	-	-	CHAP,NLPC_P60
TLS3_k127_1968545_4	290397.Adeh_1810	1.45e-174	569.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,42SZ7@68525|delta/epsilon subdivisions,2WPA5@28221|Deltaproteobacteria,2Z325@29|Myxococcales	28221|Deltaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
TLS3_k127_1968545_7	404589.Anae109_2016	8.224e-157	511.0	COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,42R2C@68525|delta/epsilon subdivisions,2WMZ7@28221|Deltaproteobacteria,2YV1V@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_1968545_12	404589.Anae109_2015	2.048e-24	120.0	COG0457@1|root,COG0457@2|Bacteria	404589.Anae109_2015|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1968545_11	404589.Anae109_2014	2.718e-26	112.0	COG1555@1|root,COG1555@2|Bacteria,1Q1N7@1224|Proteobacteria,431JQ@68525|delta/epsilon subdivisions,2WT0M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
TLS3_k127_1968545_5	1278073.MYSTI_04507	1.112e-171	548.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2WIWZ@28221|Deltaproteobacteria,2YUN0@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
TLS3_k127_1968545_1	290397.Adeh_1814	1.184e-242	757.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,42MST@68525|delta/epsilon subdivisions,2WKAN@28221|Deltaproteobacteria,2YUFR@29|Myxococcales	28221|Deltaproteobacteria	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
TLS3_k127_1968545_0	290397.Adeh_1815	2.483e-253	788.0	COG0527@1|root,COG0527@2|Bacteria,1MVSI@1224|Proteobacteria,42NCA@68525|delta/epsilon subdivisions,2WIVC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	aspartate glutamate uridylate kinase	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
TLS3_k127_1968545_6	290397.Adeh_1821	1.418e-158	512.0	COG0321@1|root,COG1051@1|root,COG0321@2|Bacteria,COG1051@2|Bacteria,1MU6A@1224|Proteobacteria,42RIC@68525|delta/epsilon subdivisions,2WNRX@28221|Deltaproteobacteria,2Z30D@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
TLS3_k127_1968545_2	290397.Adeh_1822	1.334e-229	722.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,2YTYX@29|Myxococcales	28221|Deltaproteobacteria	C	dihydrolipoamide dehydrogenase	pdhD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_1968545_13	378806.STAUR_7584	8.21e-06	58.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TLS3_k127_1968545_8	483219.LILAB_29225	1.535e-113	393.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,42MYB@68525|delta/epsilon subdivisions,2WIUY@28221|Deltaproteobacteria,2YU5E@29|Myxococcales	28221|Deltaproteobacteria	C	acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS3_k127_1968545_3	290397.Adeh_1826	4.323e-184	578.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42N06@68525|delta/epsilon subdivisions,2WK5N@28221|Deltaproteobacteria,2YTX4@29|Myxococcales	28221|Deltaproteobacteria	C	Transketolase, pyrimidine binding domain	bkdB	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K00167	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
TLS3_k127_1968545_9	290397.Adeh_1827	1.969e-33	132.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42NW8@68525|delta/epsilon subdivisions,2WJY1@28221|Deltaproteobacteria,2YV62@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
TLS3_k127_1995810_3	290397.Adeh_0965	4.404e-113	369.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2YW0C@29|Myxococcales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
TLS3_k127_1995810_2	1144275.COCOR_01001	1.799e-119	415.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,42Z25@68525|delta/epsilon subdivisions,2WUEI@28221|Deltaproteobacteria,2YUBH@29|Myxococcales	28221|Deltaproteobacteria	IQ	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_1995810_0	1144275.COCOR_02617	2.567e-148	488.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	hhoB	-	3.4.21.107	ko:K04771,ko:K08372	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	DUF1080,Transglut_core2,Trypsin_2
TLS3_k127_1995810_5	290397.Adeh_1780	7.833e-64	233.0	COG0546@1|root,COG0546@2|Bacteria,1RBMZ@1224|Proteobacteria,42RG3@68525|delta/epsilon subdivisions,2WZ2N@28221|Deltaproteobacteria,2Z16Z@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	3.6.1.1	ko:K06019	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	HAD_2
TLS3_k127_1995810_4	290397.Adeh_4078	4.4e-64	234.0	COG3884@1|root,COG3884@2|Bacteria,1NBT0@1224|Proteobacteria,42W3W@68525|delta/epsilon subdivisions,2WR9F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM Acyl-ACP thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-ACP_TE
TLS3_k127_1995810_1	1128421.JAGA01000002_gene905	9.179e-127	421.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	iAF987.Gmet_2187	CMAS
TLS3_k127_2006348_4	404589.Anae109_2230	2.542e-100	332.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,42MZF@68525|delta/epsilon subdivisions,2WNND@28221|Deltaproteobacteria,2Z2YW@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
TLS3_k127_2006348_3	404589.Anae109_2232	7.925e-117	383.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria	1224|Proteobacteria	F	Belongs to the RimK family	rimK	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK,TrkA_C
TLS3_k127_2006348_0	290397.Adeh_1580	0.0	1068.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2YUEK@29|Myxococcales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
TLS3_k127_2006348_2	404589.Anae109_2234	1.549e-144	467.0	COG1597@1|root,COG1597@2|Bacteria,1Q2E6@1224|Proteobacteria,437ZZ@68525|delta/epsilon subdivisions,2X9TP@28221|Deltaproteobacteria,2YV1J@29|Myxococcales	28221|Deltaproteobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
TLS3_k127_2006348_6	404589.Anae109_2238	3.361e-31	124.0	COG2921@1|root,COG2921@2|Bacteria,1NMJ1@1224|Proteobacteria	1224|Proteobacteria	S	Belongs to the UPF0250 family	-	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
TLS3_k127_2006348_1	243231.GSU1866	2.461e-172	550.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria,43UHM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	SMART Nucleotide binding protein, PINc	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
TLS3_k127_2027229_3	1401064.HMPREF2129_05210	0.0007555	45.0	COG4346@1|root,COG4346@2|Bacteria,2GITT@201174|Actinobacteria,22JK5@1653|Corynebacteriaceae	201174|Actinobacteria	O	Dolichyl-phosphate-mannose--protein	pmt	GO:0000030,GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
TLS3_k127_2027229_0	404589.Anae109_2365	1.97e-258	835.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1QV0D@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,MEDS,PAS_4,Response_reg,RsbRD_N
TLS3_k127_2027229_2	404589.Anae109_2366	5.637e-152	503.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42QZV@68525|delta/epsilon subdivisions,2WN5Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
TLS3_k127_2027229_1	404589.Anae109_2367	5.309e-187	595.0	COG0643@1|root,COG0745@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,1NSFS@1224|Proteobacteria	1224|Proteobacteria	T	Histidine Phosphotransfer domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
TLS3_k127_2096277_0	404589.Anae109_3042	9.231e-155	494.0	COG0437@1|root,COG5557@1|root,COG0437@2|Bacteria,COG5557@2|Bacteria,1MU1B@1224|Proteobacteria,42NS2@68525|delta/epsilon subdivisions,2WMA0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	fdnH	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4,NrfD
TLS3_k127_2096277_3	290397.Adeh_2086	5.045e-67	239.0	COG3058@1|root,COG3058@2|Bacteria,1NK06@1224|Proteobacteria,42VNJ@68525|delta/epsilon subdivisions,2WS9J@28221|Deltaproteobacteria,2Z2AD@29|Myxococcales	28221|Deltaproteobacteria	O	Necessary for formate dehydrogenase activity	fdhE	-	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
TLS3_k127_2096277_1	404589.Anae109_3047	1.969e-92	313.0	COG1526@1|root,COG1526@2|Bacteria,1NRU0@1224|Proteobacteria,42PRH@68525|delta/epsilon subdivisions,2WPXH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ,MobB
TLS3_k127_2096277_4	290397.Adeh_0957	9.957e-64	222.0	COG5637@1|root,COG5637@2|Bacteria,1MYZ7@1224|Proteobacteria,43BBB@68525|delta/epsilon subdivisions,2X6QH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
TLS3_k127_2096277_5	1265505.ATUG01000002_gene1807	8.492e-08	63.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2WIW4@28221|Deltaproteobacteria,2MJ8Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Hydrogenase (NiFe) small subunit HydA	hydA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.12.2.1,1.12.5.1,1.12.7.2,1.12.99.6	ko:K00534,ko:K05927,ko:K06282,ko:K18008	ko00633,ko01120,map00633,map01120	-	R00019,R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
TLS3_k127_2096277_2	290397.Adeh_3811	6.74e-80	277.0	COG1011@1|root,COG1011@2|Bacteria,1MVWN@1224|Proteobacteria,43DWE@68525|delta/epsilon subdivisions,2WZ1W@28221|Deltaproteobacteria,2Z153@29|Myxococcales	28221|Deltaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
TLS3_k127_2104186_3	290397.Adeh_1964	1.129e-79	271.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2Z0DF@29|Myxococcales	28221|Deltaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
TLS3_k127_2104186_1	404589.Anae109_1890	3.312e-229	719.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2WIQ1@28221|Deltaproteobacteria,2YU4J@29|Myxococcales	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
TLS3_k127_2104186_0	404589.Anae109_1891	7.4e-323	997.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,42MXV@68525|delta/epsilon subdivisions,2WIIT@28221|Deltaproteobacteria,2YY6V@29|Myxococcales	28221|Deltaproteobacteria	C	Pyruvate flavodoxin ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
TLS3_k127_2104186_2	404589.Anae109_1892	6.617e-82	283.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MRV@68525|delta/epsilon subdivisions,2WK9C@28221|Deltaproteobacteria,2YZ1X@29|Myxococcales	28221|Deltaproteobacteria	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
TLS3_k127_2116854_3	404589.Anae109_1714	5.749e-31	137.0	COG2823@1|root,COG2823@2|Bacteria,1N1R4@1224|Proteobacteria	1224|Proteobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
TLS3_k127_2116854_0	1173028.ANKO01000149_gene5566	3.111e-57	207.0	COG0561@1|root,COG0561@2|Bacteria,1G3GC@1117|Cyanobacteria,1HFBW@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,Hydrolase_3
TLS3_k127_2116854_2	1298593.TOL_0103	4.83e-44	165.0	COG0346@1|root,COG0346@2|Bacteria,1RH79@1224|Proteobacteria,1S9UN@1236|Gammaproteobacteria,1XM5X@135619|Oceanospirillales	135619|Oceanospirillales	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_2116854_4	1144275.COCOR_01394	3.111e-16	81.0	2E3SC@1|root,32YPX@2|Bacteria,1N7IU@1224|Proteobacteria,4328J@68525|delta/epsilon subdivisions,2WXE0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
TLS3_k127_2116854_1	404589.Anae109_2865	1.334e-52	190.0	COG1999@1|root,COG1999@2|Bacteria,1N19Q@1224|Proteobacteria,42XV1@68525|delta/epsilon subdivisions,2WSUD@28221|Deltaproteobacteria,2YV76@29|Myxococcales	28221|Deltaproteobacteria	S	protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
TLS3_k127_2123607_2	1254432.SCE1572_34470	2.865e-36	143.0	COG4775@1|root,COG4775@2|Bacteria,1Q2CZ@1224|Proteobacteria,437ZA@68525|delta/epsilon subdivisions,2X399@28221|Deltaproteobacteria,2YUX9@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
TLS3_k127_2123607_1	1254432.SCE1572_38880	4.244e-86	304.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,42TKC@68525|delta/epsilon subdivisions,2WQ16@28221|Deltaproteobacteria,2YWBJ@29|Myxococcales	28221|Deltaproteobacteria	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
TLS3_k127_2123607_0	290397.Adeh_3183	5.258e-233	731.0	2DPRW@1|root,COG0784@1|root,COG1352@1|root,COG2201@1|root,COG5002@1|root,3334N@2|Bacteria,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_4,Response_reg
TLS3_k127_2159648_1	290397.Adeh_0165	1.267e-143	471.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,42PSZ@68525|delta/epsilon subdivisions,2WMBH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
TLS3_k127_2159648_0	404589.Anae109_0161	7.759e-279	861.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,42M83@68525|delta/epsilon subdivisions,2WIZE@28221|Deltaproteobacteria,2YXH5@29|Myxococcales	28221|Deltaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
TLS3_k127_2159648_2	595536.ADVE02000001_gene2217	1.638e-10	68.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,2U1FH@28211|Alphaproteobacteria,36ZEE@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
TLS3_k127_2212454_4	290397.Adeh_0727	4.28e-144	462.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,2YU5P@29|Myxococcales	28221|Deltaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
TLS3_k127_2212454_20	290397.Adeh_0726	7.014e-07	62.0	COG0484@1|root,COG2199@1|root,COG0484@2|Bacteria,COG3706@2|Bacteria,1PEI3@1224|Proteobacteria,43A7R@68525|delta/epsilon subdivisions,2X3SX@28221|Deltaproteobacteria,2YX14@29|Myxococcales	28221|Deltaproteobacteria	OT	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
TLS3_k127_2212454_9	404589.Anae109_0768	5.17e-92	305.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,42RFN@68525|delta/epsilon subdivisions,2WP25@28221|Deltaproteobacteria,2YVE0@29|Myxococcales	28221|Deltaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
TLS3_k127_2212454_10	290397.Adeh_3611	2.315e-86	292.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42N6I@68525|delta/epsilon subdivisions,2WK7S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
TLS3_k127_2212454_5	404589.Anae109_3740	6.12e-123	403.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria,2YUBW@29|Myxococcales	28221|Deltaproteobacteria	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
TLS3_k127_2212454_6	404589.Anae109_3743	1.247e-116	404.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2WMR6@28221|Deltaproteobacteria,2YVVU@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
TLS3_k127_2212454_13	404589.Anae109_3744	3.915e-57	205.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,42U6G@68525|delta/epsilon subdivisions,2WQDR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0195	PgpA
TLS3_k127_2212454_1	404589.Anae109_3745	2.011e-184	596.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,42MQ4@68525|delta/epsilon subdivisions,2WMDT@28221|Deltaproteobacteria,2YUQX@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
TLS3_k127_2212454_14	404589.Anae109_3747	4.187e-48	177.0	COG3816@1|root,COG3816@2|Bacteria,1R33P@1224|Proteobacteria,42VZ9@68525|delta/epsilon subdivisions,2WRED@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09986	-	-	-	-	ko00000	-	-	-	DUF1285
TLS3_k127_2212454_0	290397.Adeh_3616	0.0	1356.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40
TLS3_k127_2212454_15	264201.pc1120	1.166e-47	188.0	COG1253@1|root,COG1253@2|Bacteria,2JGVY@204428|Chlamydiae	204428|Chlamydiae	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
TLS3_k127_2212454_19	1348657.M622_11655	1.437e-10	66.0	COG5654@1|root,COG5654@2|Bacteria,1N6P3@1224|Proteobacteria,2VSGY@28216|Betaproteobacteria,2KXJ4@206389|Rhodocyclales	206389|Rhodocyclales	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
TLS3_k127_2212454_3	404589.Anae109_3750	3.605e-156	499.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,2YWK7@29|Myxococcales	28221|Deltaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
TLS3_k127_2212454_2	518766.Rmar_1523	9.579e-158	514.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1FITT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
TLS3_k127_2212454_11	290397.Adeh_3632	1.678e-85	311.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8,YfiO
TLS3_k127_2212454_8	404589.Anae109_3758	7.626e-109	374.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
TLS3_k127_2212454_12	290397.Adeh_3634	2.188e-82	275.0	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,2YV9Q@29|Myxococcales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
TLS3_k127_2212454_7	404589.Anae109_3760	2.99e-110	360.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,42QZJ@68525|delta/epsilon subdivisions,2WNCH@28221|Deltaproteobacteria,2YYNH@29|Myxococcales	28221|Deltaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
TLS3_k127_2212454_16	290397.Adeh_3636	3.419e-34	141.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,42TGQ@68525|delta/epsilon subdivisions,2WQ6R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
TLS3_k127_2212454_18	290397.Adeh_3637	3.293e-19	92.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria,2YUDA@29|Myxococcales	28221|Deltaproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
TLS3_k127_2229526_2	290397.Adeh_0038	2.491e-157	499.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42NKD@68525|delta/epsilon subdivisions,2WIWV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
TLS3_k127_2229526_7	404589.Anae109_0040	1.642e-37	147.0	COG4747@1|root,COG4747@2|Bacteria,1RDCG@1224|Proteobacteria,42RTD@68525|delta/epsilon subdivisions,2WQBM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
TLS3_k127_2229526_5	404589.Anae109_0254	1.063e-63	226.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,42S60@68525|delta/epsilon subdivisions,2WRAR@28221|Deltaproteobacteria,2Z3BB@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
TLS3_k127_2229526_1	290397.Adeh_0232	1.467e-159	511.0	COG0707@1|root,COG0707@2|Bacteria,1MWQP@1224|Proteobacteria,42R9T@68525|delta/epsilon subdivisions,2WMWQ@28221|Deltaproteobacteria,2YTYH@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_3
TLS3_k127_2229526_6	309799.DICTH_0708	1.774e-52	191.0	COG1803@1|root,COG1803@2|Bacteria	2|Bacteria	G	methylglyoxal synthase activity	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992	MGS
TLS3_k127_2229526_0	404589.Anae109_0257	9.052e-266	825.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2WJ66@28221|Deltaproteobacteria,2YWA3@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
TLS3_k127_2245516_6	404589.Anae109_0364	1.418e-39	151.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,42M39@68525|delta/epsilon subdivisions,2WJEZ@28221|Deltaproteobacteria,2YTW3@29|Myxococcales	28221|Deltaproteobacteria	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
TLS3_k127_2245516_1	404589.Anae109_0363	1.591e-155	497.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2WJ4Y@28221|Deltaproteobacteria,2YV2A@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_1278	CBS,SIS
TLS3_k127_2245516_3	404589.Anae109_0362	1.273e-90	302.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,42MF3@68525|delta/epsilon subdivisions,2WJXS@28221|Deltaproteobacteria,2YVQQ@29|Myxococcales	28221|Deltaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
TLS3_k127_2245516_0	290397.Adeh_3025	6.879e-208	659.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42MDU@68525|delta/epsilon subdivisions,2WM9V@28221|Deltaproteobacteria,2YUA7@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_2245516_4	290397.Adeh_4066	3.717e-59	223.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,42TJ2@68525|delta/epsilon subdivisions,2WQ4P@28221|Deltaproteobacteria,2YVPS@29|Myxococcales	28221|Deltaproteobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
TLS3_k127_2245516_2	290397.Adeh_4067	8.8e-117	385.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,42NS5@68525|delta/epsilon subdivisions,2WNQ5@28221|Deltaproteobacteria,2Z357@29|Myxococcales	28221|Deltaproteobacteria	Q	Domain of unknown function (DUF2437)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
TLS3_k127_2245516_5	404589.Anae109_0355	5.755e-42	155.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2WJKT@28221|Deltaproteobacteria,2YZXG@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
TLS3_k127_2248614_9	1392498.JQLH01000001_gene1808	1.202e-10	65.0	COG1402@1|root,COG1402@2|Bacteria,4NF2C@976|Bacteroidetes,1I7A4@117743|Flavobacteriia	976|Bacteroidetes	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
TLS3_k127_2248614_5	926550.CLDAP_30490	4.332e-50	192.0	COG2210@1|root,COG2210@2|Bacteria,2G77F@200795|Chloroflexi	200795|Chloroflexi	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
TLS3_k127_2248614_4	1048834.TC41_2943	5.107e-77	281.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,278QY@186823|Alicyclobacillaceae	91061|Bacilli	P	Rhodanese Homology Domain	yrkH	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
TLS3_k127_2248614_8	867845.KI911784_gene3184	1.602e-14	86.0	COG0425@1|root,COG0425@2|Bacteria,2G7DF@200795|Chloroflexi,377DX@32061|Chloroflexia	32061|Chloroflexia	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
TLS3_k127_2248614_0	404589.Anae109_4404	1.844e-123	400.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,42S4I@68525|delta/epsilon subdivisions,2WNXV@28221|Deltaproteobacteria,2YUF1@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	fabG3	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_2248614_3	404589.Anae109_4121	1.279e-80	289.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QXM@68525|delta/epsilon subdivisions,2WMZI@28221|Deltaproteobacteria,2YV69@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
TLS3_k127_2248614_2	323261.Noc_0104	3.153e-91	320.0	COG1988@1|root,COG1988@2|Bacteria,1PCAC@1224|Proteobacteria,1RYI5@1236|Gammaproteobacteria,1X243@135613|Chromatiales	135613|Chromatiales	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
TLS3_k127_2248614_7	478741.JAFS01000002_gene77	2.808e-19	92.0	2BTHD@1|root,32NPT@2|Bacteria,46ZFX@74201|Verrucomicrobia,37H08@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2248614_6	404589.Anae109_4248	9.198e-27	112.0	2E3AG@1|root,32Y9Z@2|Bacteria,1NADT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2248614_1	290397.Adeh_2263	2.605e-110	362.0	COG2513@1|root,COG2513@2|Bacteria,1R3SD@1224|Proteobacteria	1224|Proteobacteria	G	COG2513 PEP phosphonomutase and related enzymes	MA20_35565	-	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
TLS3_k127_2271896_1	1242864.D187_000618	1.198e-295	930.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2WJ2W@28221|Deltaproteobacteria,2YUIP@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
TLS3_k127_2271896_12	404589.Anae109_0836	3.887e-37	143.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,42TN3@68525|delta/epsilon subdivisions,2WQ23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
TLS3_k127_2271896_2	215803.DB30_3996	2.491e-236	750.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,42Q8W@68525|delta/epsilon subdivisions,2WJVN@28221|Deltaproteobacteria,2YUCN@29|Myxococcales	28221|Deltaproteobacteria	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
TLS3_k127_2271896_7	290397.Adeh_0792	3.759e-110	361.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,42QRC@68525|delta/epsilon subdivisions,2WMP7@28221|Deltaproteobacteria,2YUHQ@29|Myxococcales	28221|Deltaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
TLS3_k127_2271896_6	404589.Anae109_0839	8.298e-120	390.0	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,43AKN@68525|delta/epsilon subdivisions,2X60M@28221|Deltaproteobacteria,2Z1JH@29|Myxococcales	28221|Deltaproteobacteria	K	Putative zinc-finger	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
TLS3_k127_2271896_8	290397.Adeh_0795	1.025e-106	349.0	COG3880@1|root,COG3880@2|Bacteria,1RD55@1224|Proteobacteria,42TTE@68525|delta/epsilon subdivisions,2X7MS@28221|Deltaproteobacteria,2Z2ZX@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
TLS3_k127_2271896_0	290397.Adeh_0796	0.0	1104.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	iron-sulfur binding	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
TLS3_k127_2271896_3	378806.STAUR_6773	1.703e-213	717.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Polysulphide reductase	actC	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
TLS3_k127_2271896_11	404589.Anae109_0843	5.607e-45	186.0	COG2010@1|root,COG2010@2|Bacteria,1NDP7@1224|Proteobacteria,43BBN@68525|delta/epsilon subdivisions,2X6QV@28221|Deltaproteobacteria,2Z02F@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
TLS3_k127_2271896_10	404589.Anae109_0844	1.329e-52	200.0	COG2010@1|root,COG2010@2|Bacteria,1RHGQ@1224|Proteobacteria,4393P@68525|delta/epsilon subdivisions,2X49M@28221|Deltaproteobacteria,2YYJI@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
TLS3_k127_2271896_5	290397.Adeh_0800	1.301e-139	467.0	COG4531@1|root,COG4531@2|Bacteria,1REHQ@1224|Proteobacteria,42TZ1@68525|delta/epsilon subdivisions,2WQ6N@28221|Deltaproteobacteria,2YUUI@29|Myxococcales	28221|Deltaproteobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2271896_13	404589.Anae109_0846	2.071e-21	109.0	2AGX3@1|root,3175J@2|Bacteria,1PYEE@1224|Proteobacteria,43E3Y@68525|delta/epsilon subdivisions,2WZN3@28221|Deltaproteobacteria,2Z2EI@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2271896_9	1278073.MYSTI_06703	3.425e-82	289.0	COG1999@1|root,COG1999@2|Bacteria,1R9EM@1224|Proteobacteria,42N5F@68525|delta/epsilon subdivisions,2WKG7@28221|Deltaproteobacteria,2YV22@29|Myxococcales	28221|Deltaproteobacteria	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	sco	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	-
TLS3_k127_2271896_4	290397.Adeh_0803	9.106e-143	479.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MVYW@1224|Proteobacteria,42R2B@68525|delta/epsilon subdivisions,2WN74@28221|Deltaproteobacteria,2YU9W@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c oxidase subunit II	coxB	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cytochrom_C
TLS3_k127_2307766_0	404589.Anae109_0412	5.544e-148	474.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,42NJ1@68525|delta/epsilon subdivisions,2WJ5S@28221|Deltaproteobacteria,2YX4E@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the methyltransferase superfamily	rlmL	-	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
TLS3_k127_2307766_2	404589.Anae109_0413	5.544e-79	275.0	COG2199@1|root,COG3706@2|Bacteria,1REBC@1224|Proteobacteria,42SF2@68525|delta/epsilon subdivisions,2WP98@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
TLS3_k127_2307766_1	290397.Adeh_4009	9.245e-116	377.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2YURD@29|Myxococcales	28221|Deltaproteobacteria	K	Two component transcriptional regulator, winged helix family	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_2328462_2	404589.Anae109_2496	1.421e-14	74.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,2YUIX@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
TLS3_k127_2328462_1	404589.Anae109_3327	3.505e-26	115.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_2328462_0	404589.Anae109_2493	0.0	1193.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria,2YU4B@29|Myxococcales	28221|Deltaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
TLS3_k127_235031_8	290397.Adeh_3689	1.463e-49	188.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,DnaJ
TLS3_k127_235031_7	404589.Anae109_3816	1.107e-119	394.0	COG1597@1|root,COG1597@2|Bacteria,1PV0P@1224|Proteobacteria,42XZR@68525|delta/epsilon subdivisions,2WTF1@28221|Deltaproteobacteria,2YVY3@29|Myxococcales	28221|Deltaproteobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
TLS3_k127_235031_5	290397.Adeh_3692	2.05e-136	442.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WKAF@28221|Deltaproteobacteria,2Z2Y6@29|Myxococcales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3178	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
TLS3_k127_235031_6	404589.Anae109_3820	1.623e-135	441.0	COG2270@1|root,COG2270@2|Bacteria,1QX9I@1224|Proteobacteria,43C2R@68525|delta/epsilon subdivisions,2X7DB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Nucleoside H+ symporter	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
TLS3_k127_235031_2	404589.Anae109_3352	2.148e-251	818.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,42QW3@68525|delta/epsilon subdivisions,2WNT9@28221|Deltaproteobacteria,2YWWY@29|Myxococcales	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_235031_9	290397.Adeh_3702	5.563e-33	135.0	COG3162@1|root,COG3162@2|Bacteria,1MZF3@1224|Proteobacteria,42VY2@68525|delta/epsilon subdivisions,2WRI2@28221|Deltaproteobacteria,2Z2FS@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF485	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
TLS3_k127_235031_1	404589.Anae109_3836	5.129e-259	806.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42MJE@68525|delta/epsilon subdivisions,2WK5T@28221|Deltaproteobacteria,2YWIX@29|Myxococcales	28221|Deltaproteobacteria	S	Sodium:solute symporter family	aplA	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	iAF987.Gmet_0739	SSF
TLS3_k127_235031_4	404589.Anae109_3847	9.244e-166	527.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,42N6V@68525|delta/epsilon subdivisions,2WIQC@28221|Deltaproteobacteria,2Z2Y7@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH,NTP_transferase
TLS3_k127_235031_0	404589.Anae109_3846	3.635e-260	809.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,2YTZR@29|Myxococcales	28221|Deltaproteobacteria	EK	Pyridoxal-phosphate dependent enzyme	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
TLS3_k127_235031_3	404589.Anae109_3845	4.187e-209	654.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2YTX6@29|Myxococcales	28221|Deltaproteobacteria	E	Cys Met metabolism	metC	-	2.5.1.48,4.4.1.1,4.4.1.11	ko:K01739,ko:K01758,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
TLS3_k127_2361452_8	290397.Adeh_0220	1.115e-15	77.0	COG1943@1|root,COG1943@2|Bacteria,1RBFM@1224|Proteobacteria,42QPI@68525|delta/epsilon subdivisions,2WMUC@28221|Deltaproteobacteria,2Z0AC@29|Myxococcales	28221|Deltaproteobacteria	L	High confidence in function and specificity	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
TLS3_k127_2361452_0	290397.Adeh_3339	0.0	1062.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2YUHY@29|Myxococcales	28221|Deltaproteobacteria	M	penicillin-binding protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
TLS3_k127_2361452_4	290397.Adeh_3337	5.372e-62	222.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
TLS3_k127_2361452_5	404589.Anae109_3402	5.179e-55	203.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
TLS3_k127_2361452_2	404589.Anae109_3399	5.25e-129	426.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,Yop-YscD_cpl
TLS3_k127_2361452_1	404589.Anae109_3398	1.048e-148	475.0	COG0457@1|root,COG0457@2|Bacteria,1PFUI@1224|Proteobacteria,42W2K@68525|delta/epsilon subdivisions,2WRN3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_19,TPR_8
TLS3_k127_2361452_6	404589.Anae109_3395	1.41e-40	156.0	2BT02@1|root,32N40@2|Bacteria,1Q3JG@1224|Proteobacteria,439CC@68525|delta/epsilon subdivisions,2X4KJ@28221|Deltaproteobacteria,2Z05X@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
TLS3_k127_2361452_10	1306406.ASHX01000002_gene5403	5.146e-05	53.0	COG3409@1|root,COG3409@2|Bacteria,2IBI9@201174|Actinobacteria	201174|Actinobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
TLS3_k127_2361452_3	290397.Adeh_3329	3.228e-111	376.0	COG0457@1|root,COG0457@2|Bacteria,1QX7S@1224|Proteobacteria,43C0S@68525|delta/epsilon subdivisions,2X7BD@28221|Deltaproteobacteria,2YV1Y@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2361452_9	290397.Adeh_3327	6.864e-08	53.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,42VH9@68525|delta/epsilon subdivisions,2WT3R@28221|Deltaproteobacteria,2YVNR@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
TLS3_k127_2361505_1	404589.Anae109_0043	1.309e-184	583.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WIX6@28221|Deltaproteobacteria,2Z24J@29|Myxococcales	28221|Deltaproteobacteria	C	Indolepyruvate ferredoxin oxidoreductase	iorA-1	-	1.2.7.8	ko:K00179,ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
TLS3_k127_2361505_2	290397.Adeh_0039	2.879e-69	239.0	COG1014@1|root,COG1014@2|Bacteria,1RH9B@1224|Proteobacteria,42SK4@68525|delta/epsilon subdivisions,2WPI8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	iorB-1	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
TLS3_k127_2361505_3	290397.Adeh_0037	1.694e-46	179.0	COG4747@1|root,COG4747@2|Bacteria,1RDCG@1224|Proteobacteria,42RTD@68525|delta/epsilon subdivisions,2WQBM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
TLS3_k127_2361505_0	404589.Anae109_0039	9.632e-221	699.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42MSQ@68525|delta/epsilon subdivisions,2WISJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK-1	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
TLS3_k127_2361505_4	290397.Adeh_0220	2.684e-14	73.0	COG1943@1|root,COG1943@2|Bacteria,1RBFM@1224|Proteobacteria,42QPI@68525|delta/epsilon subdivisions,2WMUC@28221|Deltaproteobacteria,2Z0AC@29|Myxococcales	28221|Deltaproteobacteria	L	High confidence in function and specificity	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
TLS3_k127_2362290_2	404589.Anae109_2699	3.967e-05	55.0	COG0745@1|root,COG1196@1|root,COG0745@2|Bacteria,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	Response_reg
TLS3_k127_2362290_0	404589.Anae109_2702	3.2e-143	464.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,42N5A@68525|delta/epsilon subdivisions,2WKKI@28221|Deltaproteobacteria,2YUUT@29|Myxococcales	28221|Deltaproteobacteria	O	AAA domain (Cdc48 subfamily)	clpB1	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
TLS3_k127_2362290_1	1242864.D187_007818	2.133e-81	290.0	COG2211@1|root,COG2211@2|Bacteria,1R0NK@1224|Proteobacteria,43CZ9@68525|delta/epsilon subdivisions,2X87H@28221|Deltaproteobacteria,2Z3MJ@29|Myxococcales	28221|Deltaproteobacteria	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_2398178_6	290397.Adeh_1562	5.647e-78	277.0	COG4987@1|root,COG4987@2|Bacteria	2|Bacteria	V	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC	cydC	-	-	ko:K06148,ko:K16012	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.129	-	-	ABC_membrane,ABC_tran
TLS3_k127_2398178_4	404589.Anae109_2255	5.942e-92	312.0	COG0457@1|root,COG0457@2|Bacteria,1QYG1@1224|Proteobacteria,43CC5@68525|delta/epsilon subdivisions,2X7N0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2398178_10	290397.Adeh_1557	2.918e-18	85.0	COG0695@1|root,COG0695@2|Bacteria,1P8SJ@1224|Proteobacteria,42XTX@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Glutaredoxin	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
TLS3_k127_2398178_2	404589.Anae109_2257	3.431e-109	377.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WMXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
TLS3_k127_2398178_0	404589.Anae109_2258	1.641e-248	786.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	nla6	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_2398178_8	404589.Anae109_2259	3.462e-35	151.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	DUF3365,GAF_2,HATPase_c,HisKA,PAS,PAS_4,Response_reg
TLS3_k127_2398178_5	290397.Adeh_1552	2.025e-82	286.0	COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,42RHI@68525|delta/epsilon subdivisions,2WNGV@28221|Deltaproteobacteria,2YV1R@29|Myxococcales	28221|Deltaproteobacteria	F	deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
TLS3_k127_2398178_3	290397.Adeh_1551	2.049e-98	331.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K04772,ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FHA,Trypsin_2
TLS3_k127_2398178_1	290397.Adeh_1549	8.716e-244	761.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
TLS3_k127_2441486_3	404589.Anae109_0206	6.911e-120	405.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,2YVCP@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0976	Chorismate_synt
TLS3_k127_2441486_5	290397.Adeh_0185	5.786e-75	279.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,42N54@68525|delta/epsilon subdivisions,2WNYG@28221|Deltaproteobacteria,2Z1BJ@29|Myxococcales	28221|Deltaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
TLS3_k127_2441486_0	404589.Anae109_0204	9.409e-210	674.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,42N01@68525|delta/epsilon subdivisions,2WKJQ@28221|Deltaproteobacteria,2YUM6@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
TLS3_k127_2441486_4	404589.Anae109_0203	2.262e-103	357.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,42MH0@68525|delta/epsilon subdivisions,2WRNN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
TLS3_k127_2441486_1	926569.ANT_01870	1.429e-125	417.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi	200795|Chloroflexi	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
TLS3_k127_2441486_8	404589.Anae109_0201	1.306e-32	132.0	COG4401@1|root,COG4401@2|Bacteria,1NANV@1224|Proteobacteria,433PN@68525|delta/epsilon subdivisions,2WX99@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Chorismate mutase of the AroH class	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
TLS3_k127_2441486_7	404589.Anae109_0197	1.003e-55	196.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2WPB9@28221|Deltaproteobacteria,2Z2ZN@29|Myxococcales	28221|Deltaproteobacteria	FG	HIT domain	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
TLS3_k127_2441486_6	404589.Anae109_0196	1.113e-60	214.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,42SMU@68525|delta/epsilon subdivisions,2WP4P@28221|Deltaproteobacteria,2YVDP@29|Myxococcales	28221|Deltaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
TLS3_k127_2441486_2	404589.Anae109_0195	5.228e-124	419.0	COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,42SUP@68525|delta/epsilon subdivisions,2WPBD@28221|Deltaproteobacteria,2YU07@29|Myxococcales	28221|Deltaproteobacteria	E	N-succinyltransferase beta subunit	astA	-	2.3.1.109	ko:K00673	ko00330,ko01100,map00330,map01100	-	R00832	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	AstA
TLS3_k127_2534151_1	404589.Anae109_2903	1.628e-199	629.0	COG0574@1|root,COG0574@2|Bacteria,1N38V@1224|Proteobacteria,42MWC@68525|delta/epsilon subdivisions,2WKAZ@28221|Deltaproteobacteria,2Z1W9@29|Myxococcales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
TLS3_k127_2534151_2	404589.Anae109_3172	6.584e-94	313.0	COG2236@1|root,COG2236@2|Bacteria,1MWNE@1224|Proteobacteria,42RSU@68525|delta/epsilon subdivisions,2WMYZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Acts on guanine, xanthine and to a lesser extent hypoxanthine	gpt	-	2.4.2.22	ko:K00769	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
TLS3_k127_2534151_0	404589.Anae109_3173	4.269e-254	792.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,42NTY@68525|delta/epsilon subdivisions,2WK4F@28221|Deltaproteobacteria,2YUKQ@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
TLS3_k127_2534151_3	404589.Anae109_3174	8.43e-74	280.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,42QQQ@68525|delta/epsilon subdivisions,2WMBP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
TLS3_k127_2542634_0	290397.Adeh_3637	8.926e-191	604.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria,2YUDA@29|Myxococcales	28221|Deltaproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
TLS3_k127_2542634_3	1408418.JNJH01000020_gene967	2.766e-05	53.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2JV8U@204441|Rhodospirillales	204441|Rhodospirillales	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TLS3_k127_2542634_1	290397.Adeh_3638	4.499e-64	229.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,42TVP@68525|delta/epsilon subdivisions,2WQ7U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
TLS3_k127_2542634_2	290397.Adeh_3640	6.539e-56	197.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2Z2X2@29|Myxococcales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TLS3_k127_2570373_10	290397.Adeh_1778	6.045e-29	121.0	COG0646@1|root,COG0646@2|Bacteria,1NPFY@1224|Proteobacteria,42PRW@68525|delta/epsilon subdivisions,2WIMG@28221|Deltaproteobacteria,2YYG9@29|Myxococcales	28221|Deltaproteobacteria	H	Methylenetetrahydrofolate reductase	metF-2	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0504	MTHFR,S-methyl_trans
TLS3_k127_2570373_4	290397.Adeh_1779	7.232e-109	379.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria,2YV42@29|Myxococcales	28221|Deltaproteobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
TLS3_k127_2570373_5	404589.Anae109_2951	1.547e-76	263.0	COG2860@1|root,COG2860@2|Bacteria,1RJQ0@1224|Proteobacteria,42ZVN@68525|delta/epsilon subdivisions,2WV9R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
TLS3_k127_2570373_1	404589.Anae109_1167	6.134e-186	607.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2YXVH@29|Myxococcales	28221|Deltaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
TLS3_k127_2570373_7	404589.Anae109_0570	2.379e-64	226.0	COG1309@1|root,COG1309@2|Bacteria,1MZ9E@1224|Proteobacteria,42X0R@68525|delta/epsilon subdivisions,2WT8N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K19736	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_7,TetR_N
TLS3_k127_2570373_3	404589.Anae109_0569	6.195e-158	507.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42NHV@68525|delta/epsilon subdivisions,2WJBA@28221|Deltaproteobacteria,2YZKZ@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
TLS3_k127_2570373_0	404589.Anae109_0568	0.0	1596.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2YX3T@29|Myxococcales	28221|Deltaproteobacteria	U	MMPL family	acrB	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
TLS3_k127_2570373_2	404589.Anae109_0567	9.545e-173	557.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WIRB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	RND efflux system, outer membrane lipoprotein, NodT family	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
TLS3_k127_2570373_9	493475.GARC_3034	1.786e-30	133.0	arCOG10456@1|root,2ZA6T@2|Bacteria,1R4VS@1224|Proteobacteria,1S209@1236|Gammaproteobacteria,466KG@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2570373_8	323097.Nham_0721	2.844e-37	156.0	COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,2U63E@28211|Alphaproteobacteria,3K009@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2,Cupin_7,DUF4437
TLS3_k127_2570373_6	1380394.JADL01000001_gene3063	2.36e-73	251.0	COG4101@1|root,COG4101@2|Bacteria,1RB8W@1224|Proteobacteria,2TUPM@28211|Alphaproteobacteria,2JWF1@204441|Rhodospirillales	204441|Rhodospirillales	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_2570373_11	580332.Slit_0032	2.218e-22	98.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VRSR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2238)	yjdF	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
TLS3_k127_2585325_4	338966.Ppro_3374	4.492e-11	69.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,43U2R@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	hemD	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
TLS3_k127_2585325_1	404589.Anae109_4251	1.938e-99	355.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42PS5@68525|delta/epsilon subdivisions,2X77E@28221|Deltaproteobacteria,2YUM9@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
TLS3_k127_2585325_2	404589.Anae109_1377	2.171e-49	186.0	2DN6S@1|root,32VV5@2|Bacteria,1NFSJ@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4265)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4265
TLS3_k127_2585325_0	404589.Anae109_1378	2.037e-202	642.0	COG0585@1|root,COG0585@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
TLS3_k127_2585325_3	290397.Adeh_2488	2.969e-27	114.0	2AMRI@1|root,32B6T@2|Bacteria,1Q1RN@1224|Proteobacteria,43EYM@68525|delta/epsilon subdivisions,2X2M7@28221|Deltaproteobacteria,2Z1YI@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2588139_3	404589.Anae109_1564	1.277e-150	482.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
TLS3_k127_2588139_2	290397.Adeh_2602	4.631e-220	698.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,43BJP@68525|delta/epsilon subdivisions,2WJWZ@28221|Deltaproteobacteria,2YUKJ@29|Myxococcales	28221|Deltaproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2,4.3.1.1	ko:K01679,ko:K01744	ko00020,ko00250,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00250,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R00490,R01082	RC00316,RC00443,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
TLS3_k127_2588139_4	404589.Anae109_0963	5.2e-117	407.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2
TLS3_k127_2588139_6	404589.Anae109_1255	1.439e-80	282.0	COG0494@1|root,COG0494@2|Bacteria,1Q2GD@1224|Proteobacteria,433T7@68525|delta/epsilon subdivisions,2X3CU@28221|Deltaproteobacteria,2YVG9@29|Myxococcales	28221|Deltaproteobacteria	L	nUDIX hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
TLS3_k127_2588139_0	290397.Adeh_1179	0.0	1407.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,42M43@68525|delta/epsilon subdivisions,2WKJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
TLS3_k127_2588139_1	243231.GSU0880	3.827e-271	861.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2WIWN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
TLS3_k127_2588139_7	404589.Anae109_2562	7.869e-68	236.0	COG1394@1|root,COG1394@2|Bacteria,1PA1A@1224|Proteobacteria,42VQ3@68525|delta/epsilon subdivisions,2WT1Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
TLS3_k127_2590905_2	290397.Adeh_2226	1.506e-182	574.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2WJ4U@28221|Deltaproteobacteria,2YVVI@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1360	Ldh_1_C,Ldh_1_N
TLS3_k127_2590905_0	404589.Anae109_2186	6.937e-267	826.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,42M56@68525|delta/epsilon subdivisions,2WJ8W@28221|Deltaproteobacteria,2YYDJ@29|Myxococcales	28221|Deltaproteobacteria	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
TLS3_k127_2590905_4	290397.Adeh_1626	9.195e-160	508.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2WJ4U@28221|Deltaproteobacteria,2YVVI@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
TLS3_k127_2590905_1	404589.Anae109_2184	1.49e-204	644.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2WJTS@28221|Deltaproteobacteria,2YU09@29|Myxococcales	28221|Deltaproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2261	ATP-grasp_2,Ligase_CoA
TLS3_k127_2590905_7	290397.Adeh_1628	3.042e-147	475.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria,2YTTU@29|Myxococcales	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,CoA_binding,Ligase_CoA
TLS3_k127_2590905_8	290397.Adeh_1629	1.511e-74	255.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2WP3R@28221|Deltaproteobacteria,2YVK9@29|Myxococcales	28221|Deltaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
TLS3_k127_2590905_6	404589.Anae109_2181	1.472e-150	489.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WJV1@28221|Deltaproteobacteria,2Z03U@29|Myxococcales	28221|Deltaproteobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
TLS3_k127_2590905_3	290397.Adeh_1631	2.492e-169	559.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2YURZ@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
TLS3_k127_2590905_5	290397.Adeh_1632	1.796e-159	506.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,2YU0F@29|Myxococcales	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
TLS3_k127_2590905_9	290397.Adeh_1634	4.279e-59	216.0	COG1520@1|root,COG1520@2|Bacteria,1Q3BK@1224|Proteobacteria,4392T@68525|delta/epsilon subdivisions,2X48J@28221|Deltaproteobacteria,2YYHQ@29|Myxococcales	28221|Deltaproteobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TLS3_k127_2599012_4	290397.Adeh_3941	7.517e-72	253.0	COG1538@1|root,COG1538@2|Bacteria,1R8XP@1224|Proteobacteria,42QGI@68525|delta/epsilon subdivisions,2X5YV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_2599012_5	1254432.SCE1572_06095	3.268e-60	231.0	COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,42R2C@68525|delta/epsilon subdivisions,2WMZ7@28221|Deltaproteobacteria,2YV1V@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_2599012_6	1123023.JIAI01000007_gene1677	3.146e-31	134.0	COG0726@1|root,COG0726@2|Bacteria,2H6C7@201174|Actinobacteria,4E3QQ@85010|Pseudonocardiales	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
TLS3_k127_2599012_0	404589.Anae109_4086	3.948e-184	589.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
TLS3_k127_2599012_3	1254432.SCE1572_38245	8.36e-81	308.0	COG1948@1|root,COG5276@1|root,COG4880@2|Bacteria,COG5276@2|Bacteria,1P2CI@1224|Proteobacteria	1224|Proteobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
TLS3_k127_2599012_2	290397.Adeh_4246	3.822e-158	524.0	COG2770@1|root,COG5000@1|root,COG2770@2|Bacteria,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,42YZ2@68525|delta/epsilon subdivisions,2X7NZ@28221|Deltaproteobacteria,2Z3HA@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_2599012_1	1144275.COCOR_01156	2.384e-166	557.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YU4M@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	sasR	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_2607010_11	1144342.PMI40_03407	0.0002035	46.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria,475RS@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
TLS3_k127_2607010_4	404589.Anae109_4174	4.749e-136	469.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,43AQI@68525|delta/epsilon subdivisions,2X64F@28221|Deltaproteobacteria	1224|Proteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,PEGA,Pkinase,TPR_12
TLS3_k127_2607010_9	290397.Adeh_3298	2.689e-47	196.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	1.1.1.42,1.3.1.85,2.7.7.7	ko:K00031,ko:K02342,ko:K14446	ko00020,ko00230,ko00240,ko00480,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko03030,ko03430,ko03440,ko04146,map00020,map00230,map00240,map00480,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map03030,map03430,map03440,map04146	M00009,M00010,M00173,M00260,M00373,M00740	R00267,R00268,R00375,R00376,R00377,R00378,R01899,R09291	RC00001,RC00084,RC00114,RC00626,RC02481,RC02795,RC02801	br01601,ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	CBS,GGDEF,PAS_9
TLS3_k127_2607010_7	290397.Adeh_0216	7.964e-91	307.0	COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,42RNT@68525|delta/epsilon subdivisions,2WNHN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_2607010_0	404589.Anae109_2390	0.0	1088.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,42NBU@68525|delta/epsilon subdivisions,2WJX9@28221|Deltaproteobacteria,2YU3V@29|Myxococcales	28221|Deltaproteobacteria	G	glycosyl transferase family	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
TLS3_k127_2607010_8	404589.Anae109_2389	1.482e-74	261.0	COG1877@1|root,COG1877@2|Bacteria,1Q1R2@1224|Proteobacteria,42U7I@68525|delta/epsilon subdivisions,2WQZE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
TLS3_k127_2607010_10	448385.sce3853	4.113e-31	138.0	COG1846@1|root,COG1846@2|Bacteria,1RKAV@1224|Proteobacteria,42VFQ@68525|delta/epsilon subdivisions,2WRWP@28221|Deltaproteobacteria,2YVC3@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	marR	-	-	-	-	-	-	-	-	-	-	-	MarR_2
TLS3_k127_2607010_1	404589.Anae109_4269	2.436e-276	865.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2WJB7@28221|Deltaproteobacteria,2YWT1@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1259	ILVD_EDD
TLS3_k127_2607010_2	404589.Anae109_0981	4.257e-205	647.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,42MB8@68525|delta/epsilon subdivisions,2WIW7@28221|Deltaproteobacteria,2YU2P@29|Myxococcales	28221|Deltaproteobacteria	C	ubiquinol oxidase subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
TLS3_k127_2607010_5	290397.Adeh_0940	5.067e-124	445.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,42UHT@68525|delta/epsilon subdivisions,2WR0M@28221|Deltaproteobacteria,2YUP9@29|Myxococcales	28221|Deltaproteobacteria	C	oxidase, subunit	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
TLS3_k127_2607010_3	1297742.A176_00964	4.808e-198	628.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_3
TLS3_k127_2607010_6	404589.Anae109_1616	3.726e-97	325.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42Q9U@68525|delta/epsilon subdivisions,2X5CC@28221|Deltaproteobacteria,2Z0TN@29|Myxococcales	28221|Deltaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
TLS3_k127_2628531_2	146922.JOFU01000002_gene7667	8.705e-146	482.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS3_k127_2628531_11	266117.Rxyl_0184	1.367e-53	205.0	COG0515@1|root,COG0515@2|Bacteria,2IAFS@201174|Actinobacteria,4CSX8@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
TLS3_k127_2628531_13	404589.Anae109_1555	3.23e-33	131.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria	1224|Proteobacteria	S	Transmembrane anti-sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
TLS3_k127_2628531_8	404589.Anae109_1554	2.418e-99	327.0	COG1595@1|root,COG1595@2|Bacteria,1RI7C@1224|Proteobacteria,42XJU@68525|delta/epsilon subdivisions,2WT13@28221|Deltaproteobacteria,2Z11E@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_2628531_1	589865.DaAHT2_0100	2.476e-180	586.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42MSQ@68525|delta/epsilon subdivisions,2WISJ@28221|Deltaproteobacteria,2MPW4@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK-1	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
TLS3_k127_2628531_10	1234664.AMRO01000021_gene1100	3.454e-77	267.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,1WE2D@129337|Geobacillus	91061|Bacilli	E	ATPases associated with a variety of cellular activities	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
TLS3_k127_2628531_9	589865.DaAHT2_0102	1.531e-90	321.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42NMG@68525|delta/epsilon subdivisions,2WJIS@28221|Deltaproteobacteria,2MIA1@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	livG	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
TLS3_k127_2628531_7	1167006.UWK_00090	6.232e-116	398.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42TE0@68525|delta/epsilon subdivisions,2WPEP@28221|Deltaproteobacteria,2MKDG@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
TLS3_k127_2628531_6	1121403.AUCV01000001_gene869	1.01e-117	404.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42MKP@68525|delta/epsilon subdivisions,2WJU9@28221|Deltaproteobacteria,2MJJN@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
TLS3_k127_2628531_4	1167006.UWK_00092	4.458e-134	458.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,42MXX@68525|delta/epsilon subdivisions,2WKJM@28221|Deltaproteobacteria,2MHQS@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
TLS3_k127_2628531_3	589865.DaAHT2_0105	1.951e-145	472.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,42MXX@68525|delta/epsilon subdivisions,2WKJM@28221|Deltaproteobacteria,2MHQS@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
TLS3_k127_2628531_5	290397.Adeh_2268	7.699e-127	416.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase type 11	ubiE_1	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
TLS3_k127_2628531_12	1380394.JADL01000010_gene4229	5.404e-47	184.0	COG0457@1|root,COG2207@1|root,COG0457@2|Bacteria,COG2207@2|Bacteria,1R81X@1224|Proteobacteria,2U0BK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
TLS3_k127_2628531_0	269799.Gmet_2075	3.196e-194	610.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,42QBB@68525|delta/epsilon subdivisions,2WKEZ@28221|Deltaproteobacteria,43T67@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_2629794_1	404589.Anae109_0787	2.032e-117	390.0	COG1235@1|root,COG1235@2|Bacteria,1MYCI@1224|Proteobacteria,42SMF@68525|delta/epsilon subdivisions,2WPBT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
TLS3_k127_2629794_2	404589.Anae109_0788	1.61e-85	286.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2WP5X@28221|Deltaproteobacteria,2Z0FU@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
TLS3_k127_2629794_4	404589.Anae109_0789	5.995e-70	246.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,42S5S@68525|delta/epsilon subdivisions,2WNSS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Lysin motif	-	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
TLS3_k127_2629794_0	290397.Adeh_0753	1.967e-125	413.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,2YVC8@29|Myxococcales	28221|Deltaproteobacteria	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
TLS3_k127_2629794_3	404589.Anae109_0435	6.332e-74	254.0	COG0584@1|root,COG0584@2|Bacteria,1MW6Z@1224|Proteobacteria	1224|Proteobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
TLS3_k127_2630636_1	861299.J421_1872	1.773e-227	710.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
TLS3_k127_2630636_5	290397.Adeh_2205	1.681e-143	482.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42N8V@68525|delta/epsilon subdivisions,2WJWB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
TLS3_k127_2630636_2	404589.Anae109_2138	1.774e-198	620.0	COG0282@1|root,COG3957@1|root,COG0282@2|Bacteria,COG3957@2|Bacteria,1MW61@1224|Proteobacteria,42MJA@68525|delta/epsilon subdivisions,2WJBJ@28221|Deltaproteobacteria,2YUMX@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase,XFP,XFP_C,XFP_N
TLS3_k127_2630636_0	290397.Adeh_3116	0.0	1403.0	COG0282@1|root,COG3957@1|root,COG0282@2|Bacteria,COG3957@2|Bacteria,1MW61@1224|Proteobacteria,42MJA@68525|delta/epsilon subdivisions,2WJBJ@28221|Deltaproteobacteria,2YUMX@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase,XFP,XFP_C,XFP_N
TLS3_k127_2630636_7	290397.Adeh_1125	2.248e-65	230.0	COG0288@1|root,COG0288@2|Bacteria,1R3SC@1224|Proteobacteria,42VNU@68525|delta/epsilon subdivisions,2WRX5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
TLS3_k127_2630636_3	404589.Anae109_0566	4.472e-172	547.0	COG2211@1|root,COG2211@2|Bacteria,1QVH9@1224|Proteobacteria,43BQR@68525|delta/epsilon subdivisions,2X71T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_2630636_4	1242864.D187_003353	2.608e-151	490.0	COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,42NU4@68525|delta/epsilon subdivisions,2WKV0@28221|Deltaproteobacteria,2YVPN@29|Myxococcales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
TLS3_k127_2630636_8	1187851.A33M_0764	5.777e-41	170.0	COG2323@1|root,COG2323@2|Bacteria,1MW5I@1224|Proteobacteria,2U958@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
TLS3_k127_2630636_6	483219.LILAB_29705	2.91e-107	380.0	COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria,42M4K@68525|delta/epsilon subdivisions,2WWCN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
TLS3_k127_2645759_1	290397.Adeh_3937	2.07e-131	428.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42NUK@68525|delta/epsilon subdivisions,2WJTJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_2645759_2	404589.Anae109_0498	1.094e-115	395.0	COG2834@1|root,COG2834@2|Bacteria,1R5CY@1224|Proteobacteria,42PWK@68525|delta/epsilon subdivisions,2WKW1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
TLS3_k127_2645759_0	404589.Anae109_0499	3.424e-136	458.0	2DNEA@1|root,32X2Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2662345_7	1116472.MGMO_105c00560	3.127e-28	132.0	COG1999@1|root,COG2010@1|root,COG1999@2|Bacteria,COG2010@2|Bacteria,1R725@1224|Proteobacteria,1S1UW@1236|Gammaproteobacteria,1XFRR@135618|Methylococcales	135618|Methylococcales	C	SCO1/SenC	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,SCO1-SenC
TLS3_k127_2662345_1	3988.XP_002534646.1	2.168e-251	794.0	COG2132@1|root,2QR4X@2759|Eukaryota,37N45@33090|Viridiplantae,3GBPZ@35493|Streptophyta	33090|Viridiplantae	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,peroxidase
TLS3_k127_2662345_2	1380390.JIAT01000010_gene4575	6.406e-138	452.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CSGP@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
TLS3_k127_2662345_4	391625.PPSIR1_31628	2.938e-51	196.0	COG2267@1|root,COG2267@2|Bacteria,1MYEX@1224|Proteobacteria,43CP1@68525|delta/epsilon subdivisions,2X7WC@28221|Deltaproteobacteria,2Z2N6@29|Myxococcales	28221|Deltaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_2662345_6	404589.Anae109_1603	2.422e-39	152.0	COG0745@1|root,COG0745@2|Bacteria	404589.Anae109_1603|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2662345_0	290397.Adeh_1428	1.062e-300	934.0	COG0343@1|root,COG4121@1|root,COG0343@2|Bacteria,COG4121@2|Bacteria,1MUCA@1224|Proteobacteria,42YYV@68525|delta/epsilon subdivisions,2WTRR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	-	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	Methyltransf_30,TGT
TLS3_k127_2662345_5	33898.JRHJ01000041_gene4496	2.89e-42	168.0	COG0680@1|root,COG0680@2|Bacteria,2GN48@201174|Actinobacteria	201174|Actinobacteria	C	TIGRFAM hydrogenase maturation protease	hupD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
TLS3_k127_2662345_3	1155718.KB891878_gene5574	8.193e-102	350.0	2DBQJ@1|root,2ZAF2@2|Bacteria,2I2YB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2662345_8	1463881.KL591010_gene5139	1.546e-17	84.0	2ADVU@1|root,313MT@2|Bacteria,2H7PH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2672487_5	485913.Krac_0872	7.235e-19	93.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
TLS3_k127_2672487_3	378806.STAUR_3540	5.181e-122	410.0	COG4225@1|root,COG4225@2|Bacteria,1NQTS@1224|Proteobacteria,4321U@68525|delta/epsilon subdivisions,2WX0K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glycosyl Hydrolase Family 88	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
TLS3_k127_2672487_2	1242864.D187_006418	2.396e-154	529.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,42MBY@68525|delta/epsilon subdivisions,2WIR5@28221|Deltaproteobacteria,2YUKC@29|Myxococcales	28221|Deltaproteobacteria	C	alcohol dehydrogenase	-	-	1.1.1.61	ko:K00043	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R01644	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
TLS3_k127_2672487_1	378806.STAUR_6310	2.572e-238	742.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2YU53@29|Myxococcales	28221|Deltaproteobacteria	E	glutamine synthetase	glnA1	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N_2
TLS3_k127_2672487_0	215803.DB30_2362	1.944e-249	797.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,2YTZ3@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.99	ko:K00128,ko:K09472	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00136	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R07417,R07418,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_2672487_4	378806.STAUR_6311	2.683e-73	255.0	COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,42SRU@68525|delta/epsilon subdivisions,2WPAI@28221|Deltaproteobacteria,2YVFH@29|Myxococcales	28221|Deltaproteobacteria	F	Peptidase C26	guaA2	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
TLS3_k127_2681523_4	290397.Adeh_0365	5.437e-29	117.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria,2YVC9@29|Myxococcales	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
TLS3_k127_2681523_0	290397.Adeh_0366	5.883e-191	601.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2WIQU@28221|Deltaproteobacteria,2YTSK@29|Myxococcales	28221|Deltaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TLS3_k127_2681523_2	290397.Adeh_0368	4.874e-66	247.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,432MH@68525|delta/epsilon subdivisions,2WYFU@28221|Deltaproteobacteria,2YVDK@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
TLS3_k127_2681523_1	404589.Anae109_4209	5.717e-128	420.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,42MXH@68525|delta/epsilon subdivisions,2WK8E@28221|Deltaproteobacteria,2Z0NY@29|Myxococcales	28221|Deltaproteobacteria	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
TLS3_k127_2681523_3	290397.Adeh_0370	1.403e-34	134.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42MJ7@68525|delta/epsilon subdivisions,2WIRS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	PFAM amidohydrolase	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
TLS3_k127_2724841_5	357808.RoseRS_0121	4.975e-15	76.0	COG0679@1|root,COG0679@2|Bacteria,2G7V4@200795|Chloroflexi,376PB@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
TLS3_k127_2724841_4	1121920.AUAU01000004_gene848	1.364e-22	102.0	COG1544@1|root,COG1544@2|Bacteria,3Y926@57723|Acidobacteria	57723|Acidobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
TLS3_k127_2724841_6	562743.JH976434_gene1122	0.0004091	51.0	2EFZF@1|root,339RM@2|Bacteria,1VMG6@1239|Firmicutes,4HR8G@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2724841_3	215803.DB30_2712	3.076e-46	177.0	COG0697@1|root,COG0697@2|Bacteria,1Q3JS@1224|Proteobacteria,439CP@68525|delta/epsilon subdivisions,2X4M1@28221|Deltaproteobacteria,2YZ8B@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_2724841_0	404589.Anae109_1169	2.717e-270	845.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,42NAD@68525|delta/epsilon subdivisions,2WKEY@28221|Deltaproteobacteria,2Z1IJ@29|Myxococcales	28221|Deltaproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
TLS3_k127_2724841_1	290397.Adeh_2245	9.782e-260	807.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,42MVJ@68525|delta/epsilon subdivisions,2WKM4@28221|Deltaproteobacteria,2YTUB@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_2724841_2	335543.Sfum_0314	3.799e-51	191.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,42PN2@68525|delta/epsilon subdivisions,2WM53@28221|Deltaproteobacteria,2MRX0@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
TLS3_k127_2737818_3	290397.Adeh_2841	4.191e-130	420.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
TLS3_k127_2737818_0	404589.Anae109_2771	0.0	1042.0	COG1389@1|root,COG1389@2|Bacteria,1R6T0@1224|Proteobacteria,42YI1@68525|delta/epsilon subdivisions,2WTHV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,HATPase_c_3,Topo-VIb_trans
TLS3_k127_2737818_1	404589.Anae109_2770	5.529e-195	644.0	COG1697@1|root,COG1697@2|Bacteria,1NBFJ@1224|Proteobacteria,4314R@68525|delta/epsilon subdivisions,2WWNC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA topoisomerase VI subunit A	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
TLS3_k127_2737818_5	502025.Hoch_3449	5.338e-32	135.0	COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,42U2Q@68525|delta/epsilon subdivisions,2WQK9@28221|Deltaproteobacteria,2YW3Q@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
TLS3_k127_2737818_2	290397.Adeh_2843	1.049e-148	486.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,42UGV@68525|delta/epsilon subdivisions,2WR1G@28221|Deltaproteobacteria,2YUDE@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_2737818_7	404589.Anae109_2778	4.628e-20	90.0	COG1225@1|root,COG1225@2|Bacteria,1RER0@1224|Proteobacteria,4399V@68525|delta/epsilon subdivisions,2X4HB@28221|Deltaproteobacteria,2YZ0N@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
TLS3_k127_2737818_6	404589.Anae109_2778	3.093e-29	119.0	COG1225@1|root,COG1225@2|Bacteria,1RER0@1224|Proteobacteria,4399V@68525|delta/epsilon subdivisions,2X4HB@28221|Deltaproteobacteria,2YZ0N@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
TLS3_k127_2737818_4	404589.Anae109_2780	2.414e-58	209.0	COG0354@1|root,COG0354@2|Bacteria,1QYGE@1224|Proteobacteria,43CCJ@68525|delta/epsilon subdivisions,2WYDB@28221|Deltaproteobacteria,2Z3H2@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
TLS3_k127_2755790_0	1536774.H70357_31005	8.659e-194	610.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,4HC0P@91061|Bacilli,26TNT@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU08790	ThiC-associated,ThiC_Rad_SAM
TLS3_k127_2755790_3	404589.Anae109_1990	4.927e-128	421.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,42NBV@68525|delta/epsilon subdivisions,2WK0F@28221|Deltaproteobacteria,2YUYV@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
TLS3_k127_2755790_5	667121.ET1_26_00020	3.607e-14	75.0	COG0607@1|root,COG0607@2|Bacteria,1MZYZ@1224|Proteobacteria,1SBB7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	SMART Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS3_k127_2755790_2	290397.Adeh_1829	1.722e-146	471.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QB7@68525|delta/epsilon subdivisions,2WM6Y@28221|Deltaproteobacteria,2Z2WK@29|Myxococcales	28221|Deltaproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
TLS3_k127_2755790_1	290397.Adeh_1828	2.811e-164	526.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,42P2E@68525|delta/epsilon subdivisions,2WIJQ@28221|Deltaproteobacteria,2YUQJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
TLS3_k127_2755790_4	290397.Adeh_1827	5.253e-112	372.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42NW8@68525|delta/epsilon subdivisions,2WJY1@28221|Deltaproteobacteria,2YV62@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
TLS3_k127_2781334_0	290397.Adeh_1374	7.017e-143	466.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1,dCache_2,dCache_3,sCache_2
TLS3_k127_2781334_2	404589.Anae109_2559	4.121e-104	342.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,42S2Z@68525|delta/epsilon subdivisions,2X5JB@28221|Deltaproteobacteria,2Z35Y@29|Myxococcales	28221|Deltaproteobacteria	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
TLS3_k127_2781334_3	290397.Adeh_1824	7.293e-103	343.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,42SXI@68525|delta/epsilon subdivisions,2WPTR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
TLS3_k127_2781334_1	404589.Anae109_1997	3.096e-113	385.0	COG1179@1|root,COG1179@2|Bacteria	2|Bacteria	H	involved in molybdopterin and THIamine biosynthesis family 1	ygdL	GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.7.7.73,2.7.7.80	ko:K03148,ko:K21029,ko:K22132	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000,ko03016	-	-	-	ThiF
TLS3_k127_2781334_5	290397.Adeh_2983	5.344e-85	287.0	COG3897@1|root,COG3897@2|Bacteria,1N9VC@1224|Proteobacteria,435VU@68525|delta/epsilon subdivisions,2X0BN@28221|Deltaproteobacteria,2Z0RC@29|Myxococcales	28221|Deltaproteobacteria	S	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	-	-	-	-	-	-	-	-	-	PrmA
TLS3_k127_2781334_4	290397.Adeh_2049	3.014e-101	337.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,42N1F@68525|delta/epsilon subdivisions,2WK2V@28221|Deltaproteobacteria,2YVBJ@29|Myxococcales	28221|Deltaproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153,ko:K21219	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2909	Phos_pyr_kin,TMP-TENI,ThiP_synth
TLS3_k127_2783246_5	404589.Anae109_0628	1.365e-46	169.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,42NHY@68525|delta/epsilon subdivisions,2WKAP@28221|Deltaproteobacteria,2Z1NX@29|Myxococcales	28221|Deltaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	ghr	-	1.1.1.31,1.1.1.60,1.1.1.79	ko:K00020,ko:K00042,ko:K18121	ko00280,ko00630,ko00650,ko01100,ko01120,ko01200,map00280,map00630,map00650,map01100,map01120,map01200	-	R00465,R01745,R01747,R05066,R09281	RC00042,RC00087,RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
TLS3_k127_2783246_6	404589.Anae109_0625	7.359e-44	164.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HATPase_c,Response_reg
TLS3_k127_2783246_2	404589.Anae109_0624	6.512e-139	461.0	COG2378@1|root,COG2378@2|Bacteria,1P2ZE@1224|Proteobacteria,42QIS@68525|delta/epsilon subdivisions,2WMK0@28221|Deltaproteobacteria,2YV96@29|Myxococcales	28221|Deltaproteobacteria	K	WYL domain	-	-	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
TLS3_k127_2783246_7	1379270.AUXF01000007_gene1064	1.446e-18	100.0	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	-	-	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
TLS3_k127_2783246_4	290397.Adeh_0579	9.248e-58	224.0	COG4493@1|root,COG4493@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1054)	yktB	-	-	-	-	-	-	-	-	-	-	-	DUF1054
TLS3_k127_2783246_1	290397.Adeh_0577	8.535e-193	630.0	COG4191@1|root,COG4191@2|Bacteria,1MY5P@1224|Proteobacteria,42MTA@68525|delta/epsilon subdivisions,2WJ9Q@28221|Deltaproteobacteria,2YUZA@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,HAMP,HATPase_c,HisKA
TLS3_k127_2783246_0	404589.Anae109_0619	6.057e-216	689.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria,2YUUX@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_2828957_3	404589.Anae109_3346	3.507e-41	154.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,42YBA@68525|delta/epsilon subdivisions,2WUP5@28221|Deltaproteobacteria,2YX31@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase, M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
TLS3_k127_2828957_0	404589.Anae109_3348	4.234e-159	507.0	COG1063@1|root,COG1063@2|Bacteria,1R8JQ@1224|Proteobacteria,4374D@68525|delta/epsilon subdivisions,2X3P4@28221|Deltaproteobacteria,2YWQG@29|Myxococcales	28221|Deltaproteobacteria	E	alcohol dehydrogenase	-	-	1.4.1.11	ko:K18012	ko00310,map00310	-	R03349	RC00888	ko00000,ko00001,ko01000	-	-	-	-
TLS3_k127_2828957_1	1385517.N800_12250	1.432e-148	501.0	COG1228@1|root,COG1228@2|Bacteria,1MY4V@1224|Proteobacteria,1RZRK@1236|Gammaproteobacteria,1X4X1@135614|Xanthomonadales	135614|Xanthomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
TLS3_k127_2828957_2	404589.Anae109_3442	4.672e-96	318.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS3_k127_2868153_8	290397.Adeh_3475	2.997e-155	498.0	COG1181@1|root,COG1181@2|Bacteria,1QXU6@1224|Proteobacteria,43C6Q@68525|delta/epsilon subdivisions,2X7NN@28221|Deltaproteobacteria,2Z3H4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2868153_14	290397.Adeh_3476	1.293e-62	223.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,42TN4@68525|delta/epsilon subdivisions,2WQ0Q@28221|Deltaproteobacteria,2YVM4@29|Myxococcales	28221|Deltaproteobacteria	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
TLS3_k127_2868153_10	404589.Anae109_3588	2.289e-92	317.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria	1224|Proteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG_1	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
TLS3_k127_2868153_18	234267.Acid_4200	5.43e-26	113.0	COG0316@1|root,COG0316@2|Bacteria,3Y4ZB@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
TLS3_k127_2868153_11	404589.Anae109_3590	1.34e-81	277.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2WN14@28221|Deltaproteobacteria,2YVW4@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_2868153_9	290397.Adeh_3480	2.61e-127	411.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,42MA4@68525|delta/epsilon subdivisions,2WIPU@28221|Deltaproteobacteria,2Z1UM@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-(Acyl carrier protein) reductase	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_2868153_13	290397.Adeh_3482	1.476e-65	231.0	COG0746@1|root,COG0746@2|Bacteria,1QXVT@1224|Proteobacteria,42U4M@68525|delta/epsilon subdivisions,2WQUV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
TLS3_k127_2868153_19	290397.Adeh_1241	1.013e-24	115.0	COG3047@1|root,COG3047@2|Bacteria	2|Bacteria	-	-	ompW	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	PagL
TLS3_k127_2868153_20	290397.Adeh_3781	2.562e-20	99.0	COG3047@1|root,COG3047@2|Bacteria,1QAKM@1224|Proteobacteria,4355Q@68525|delta/epsilon subdivisions,2WZGM@28221|Deltaproteobacteria,2Z23W@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2868153_23	215803.DB30_3130	1.031e-12	79.0	COG2273@1|root,COG2273@2|Bacteria,1Q24F@1224|Proteobacteria,43F1J@68525|delta/epsilon subdivisions,2X30E@28221|Deltaproteobacteria,2YTW9@29|Myxococcales	28221|Deltaproteobacteria	G	Carbohydrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Glyco_hydro_16
TLS3_k127_2868153_5	404589.Anae109_1586	4.662e-191	603.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,43C9A@68525|delta/epsilon subdivisions,2X7JQ@28221|Deltaproteobacteria,2Z192@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	AIF_C,Pyr_redox_2,Reductase_C,Rieske
TLS3_k127_2868153_3	404589.Anae109_4235	3.035e-240	761.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WKNF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Carbon starvation protein CstA	-	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
TLS3_k127_2868153_25	1265505.ATUG01000002_gene1681	7.062e-08	66.0	COG0840@1|root,COG0840@2|Bacteria,1RFH2@1224|Proteobacteria,42YXY@68525|delta/epsilon subdivisions,2WUDW@28221|Deltaproteobacteria,2MMQN@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,Hemerythrin,MCPsignal
TLS3_k127_2868153_24	748247.AZKH_p0190	8.995e-09	64.0	2DNR5@1|root,32YQH@2|Bacteria,1NBXJ@1224|Proteobacteria,2VW7K@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2868153_0	296591.Bpro_4149	0.0	1140.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VKRS@28216|Betaproteobacteria,4AAXQ@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
TLS3_k127_2868153_16	159087.Daro_1632	9.294e-40	172.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2VT7U@28216|Betaproteobacteria,2KWBT@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_2868153_4	296591.Bpro_4151	8.615e-194	636.0	COG2176@1|root,COG5002@1|root,COG2176@2|Bacteria,COG5002@2|Bacteria,1QUVW@1224|Proteobacteria,2VHZ3@28216|Betaproteobacteria,4AD1W@80864|Comamonadaceae	28216|Betaproteobacteria	L	Exonuclease	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
TLS3_k127_2868153_2	1382306.JNIM01000001_gene2330	1.71e-308	967.0	COG0365@1|root,COG0365@2|Bacteria,2G83G@200795|Chloroflexi	200795|Chloroflexi	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
TLS3_k127_2868153_1	404589.Anae109_3011	0.0	1063.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,1MUIY@1224|Proteobacteria,42NBU@68525|delta/epsilon subdivisions,2WJX9@28221|Deltaproteobacteria,2YU3V@29|Myxococcales	28221|Deltaproteobacteria	G	glycosyl transferase family	otsAB	-	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,S6PP,Trehalose_PPase
TLS3_k127_2868153_22	309801.trd_A0835	3.939e-17	90.0	COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi,27YN5@189775|Thermomicrobia	189775|Thermomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS3_k127_2868153_12	404589.Anae109_2751	7.684e-73	252.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria,2YUYA@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
TLS3_k127_2868153_6	290397.Adeh_3522	1.507e-171	551.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
TLS3_k127_2868153_7	290397.Adeh_3523	1.557e-160	527.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
TLS3_k127_2868153_21	1242864.D187_010009	9.366e-19	96.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_2952555_2	404589.Anae109_2680	5.033e-276	853.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2WJB0@28221|Deltaproteobacteria,2YUTM@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the argininosuccinate synthase family. Type	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
TLS3_k127_2952555_1	290397.Adeh_1807	2.614e-277	859.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
TLS3_k127_2952555_0	404589.Anae109_2021	0.0	1126.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2YWBK@29|Myxococcales	28221|Deltaproteobacteria	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
TLS3_k127_2952555_3	1146883.BLASA_1782	9.621e-12	72.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
TLS3_k127_296344_1	246197.MXAN_3671	1.824e-250	784.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WTZ0@28221|Deltaproteobacteria,2YUKM@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
TLS3_k127_296344_2	483219.LILAB_26495	3.012e-165	536.0	COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,42T6A@68525|delta/epsilon subdivisions,2WPV8@28221|Deltaproteobacteria,2YUNA@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
TLS3_k127_296344_3	483219.LILAB_26500	7.915e-24	111.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	MA20_39340	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS3_k127_296344_0	404589.Anae109_1757	1.121e-316	1000.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
TLS3_k127_296344_4	404589.Anae109_3442	2.266e-10	64.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS3_k127_2972818_9	215803.DB30_8344	7.242e-47	186.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,42QEZ@68525|delta/epsilon subdivisions,2WKTP@28221|Deltaproteobacteria,2YYPJ@29|Myxococcales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_2972818_0	404589.Anae109_0087	0.0	1773.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WJ2H@28221|Deltaproteobacteria,2YX1T@29|Myxococcales	28221|Deltaproteobacteria	H	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
TLS3_k127_2972818_13	290397.Adeh_0384	8.876e-16	86.0	COG5608@1|root,COG5608@2|Bacteria,1QE53@1224|Proteobacteria,42XG2@68525|delta/epsilon subdivisions,2WSRR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
TLS3_k127_2972818_3	404589.Anae109_0078	3.618e-193	614.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2YTXF@29|Myxococcales	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
TLS3_k127_2972818_6	404589.Anae109_0077	8.968e-74	258.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,42N1F@68525|delta/epsilon subdivisions,2WK2V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153,ko:K21219	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2909	Phos_pyr_kin,TMP-TENI,ThiP_synth
TLS3_k127_2972818_5	290397.Adeh_0076	5.496e-75	284.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,43B6K@68525|delta/epsilon subdivisions,2X6K5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
TLS3_k127_2972818_7	404589.Anae109_0075	1.136e-68	240.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42R5Z@68525|delta/epsilon subdivisions,2WMPN@28221|Deltaproteobacteria,2YVXC@29|Myxococcales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
TLS3_k127_2972818_4	404589.Anae109_0073	1.192e-181	580.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42N89@68525|delta/epsilon subdivisions,2WIUT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
TLS3_k127_2972818_11	290397.Adeh_0072	1.158e-24	117.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
TLS3_k127_2972818_8	404589.Anae109_0071	1.683e-67	256.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,42SQE@68525|delta/epsilon subdivisions,2WPQK@28221|Deltaproteobacteria,2Z324@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
TLS3_k127_2972818_2	290397.Adeh_0069	4.219e-219	699.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WJ4H@28221|Deltaproteobacteria,2YU21@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AAA_26,Aminotran_3
TLS3_k127_2972818_10	290397.Adeh_0068	7.494e-38	151.0	COG2755@1|root,COG2755@2|Bacteria,1PS6U@1224|Proteobacteria,43315@68525|delta/epsilon subdivisions,2WXTN@28221|Deltaproteobacteria,2YY6Z@29|Myxococcales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS3_k127_2972818_1	404589.Anae109_0068	1.774e-304	944.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2WJCQ@28221|Deltaproteobacteria,2YU1P@29|Myxococcales	28221|Deltaproteobacteria	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
TLS3_k127_2981138_2	1121939.L861_01755	1.079e-49	192.0	COG3629@1|root,COG3629@2|Bacteria,1QU9N@1224|Proteobacteria	1224|Proteobacteria	K	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,BTAD
TLS3_k127_2981138_1	1510531.JQJJ01000008_gene3768	6.616e-134	437.0	COG0500@1|root,COG0500@2|Bacteria,1N3PV@1224|Proteobacteria,2TVNH@28211|Alphaproteobacteria,3JUBW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
TLS3_k127_2981138_0	715226.ABI_22470	1.669e-166	538.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,2TRTV@28211|Alphaproteobacteria,2KH40@204458|Caulobacterales	204458|Caulobacterales	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
TLS3_k127_2981138_3	661478.OP10G_0472	2.787e-22	108.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,MEDS,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_3038572_4	404589.Anae109_1897	1.675e-12	71.0	COG0457@1|root,COG0457@2|Bacteria	404589.Anae109_1897|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3038572_3	404589.Anae109_1899	1.068e-27	113.0	2AIXI@1|root,319F6@2|Bacteria,1Q2J0@1224|Proteobacteria,4385U@68525|delta/epsilon subdivisions,2X3FN@28221|Deltaproteobacteria,2YVWG@29|Myxococcales	28221|Deltaproteobacteria	S	Ribbon-helix-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	RHH_3
TLS3_k127_3038572_0	290397.Adeh_1955	2.517e-167	529.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42MI8@68525|delta/epsilon subdivisions,2WJDT@28221|Deltaproteobacteria,2YU9G@29|Myxococcales	28221|Deltaproteobacteria	GM	NAD-dependent epimerase dehydratase	rmlB2	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
TLS3_k127_3038572_1	290397.Adeh_1954	1.191e-147	484.0	COG0451@1|root,COG0451@2|Bacteria,1QX8V@1224|Proteobacteria,43C1V@68525|delta/epsilon subdivisions,2X5FV@28221|Deltaproteobacteria,2Z35E@29|Myxococcales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
TLS3_k127_3038572_2	404589.Anae109_3224	2.534e-41	159.0	2E36Z@1|root,32Y6R@2|Bacteria,1NCM6@1224|Proteobacteria,43DZC@68525|delta/epsilon subdivisions,2WZ9K@28221|Deltaproteobacteria,2Z1N9@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_304232_2	1211114.ALIP01000022_gene2425	4.633e-90	312.0	COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,1RNTQ@1236|Gammaproteobacteria,1X2Y2@135614|Xanthomonadales	135614|Xanthomonadales	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
TLS3_k127_304232_3	1278073.MYSTI_07425	4.638e-89	309.0	COG4555@1|root,COG4555@2|Bacteria,1QU2T@1224|Proteobacteria,43BX9@68525|delta/epsilon subdivisions,2X782@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CP	ABC transporter	natA	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	-	ABC_tran
TLS3_k127_304232_4	483219.LILAB_12330	8.866e-80	289.0	COG1668@1|root,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,43B64@68525|delta/epsilon subdivisions,2X6JN@28221|Deltaproteobacteria,2YVQ4@29|Myxococcales	28221|Deltaproteobacteria	CP	sodium ABC transporter, permease	-	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,Abi
TLS3_k127_304232_1	404589.Anae109_0896	4.629e-116	401.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2WIJJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
TLS3_k127_304232_0	404589.Anae109_0895	6.031e-138	447.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42P7V@68525|delta/epsilon subdivisions,2WJQA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC-2 type transporter	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
TLS3_k127_3050074_5	1305836.AXVE01000003_gene2312	2.896e-47	186.0	COG3919@1|root,COG3919@2|Bacteria,1TQPN@1239|Firmicutes,4HDZ1@91061|Bacilli	91061|Bacilli	S	ATP-grasp enzyme	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2
TLS3_k127_3050074_2	404589.Anae109_1709	3.084e-121	404.0	COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,4304Z@68525|delta/epsilon subdivisions,2WVJ8@28221|Deltaproteobacteria,2YV3F@29|Myxococcales	28221|Deltaproteobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	topI	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
TLS3_k127_3050074_1	290397.Adeh_3420	6.564e-147	471.0	COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,42ZDK@68525|delta/epsilon subdivisions,2WUNQ@28221|Deltaproteobacteria,2YU41@29|Myxococcales	28221|Deltaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
TLS3_k127_3050074_4	290397.Adeh_3421	4.101e-75	272.0	COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,42ZZH@68525|delta/epsilon subdivisions,2WVGR@28221|Deltaproteobacteria,2YUQ1@29|Myxococcales	28221|Deltaproteobacteria	O	maleylacetoacetate isomerase	maiA	-	5.2.1.2,5.2.1.4	ko:K01800,ko:K01801	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R03181,R03868	RC00867	ko00000,ko00001,ko00002,ko01000	-	-	-	GST_C_3,GST_N,GST_N_3
TLS3_k127_3050074_0	404589.Anae109_3484	4.599e-202	641.0	COG3185@1|root,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,42R5V@68525|delta/epsilon subdivisions,2WMYF@28221|Deltaproteobacteria,2YU6U@29|Myxococcales	28221|Deltaproteobacteria	C	dioxygenase	hppD	-	1.13.11.27,1.13.11.46	ko:K00457,ko:K16421	ko00130,ko00261,ko00350,ko00360,ko01055,ko01100,ko01130,map00130,map00261,map00350,map00360,map01055,map01100,map01130	M00044	R01372,R02521,R06632	RC00505,RC00738,RC01471	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
TLS3_k127_3050074_3	290397.Adeh_3423	5.562e-110	381.0	COG3508@1|root,COG3508@2|Bacteria,1MV9G@1224|Proteobacteria,42U01@68525|delta/epsilon subdivisions,2WQQ3@28221|Deltaproteobacteria,2YU39@29|Myxococcales	28221|Deltaproteobacteria	C	homogentisate 12-dioxygenase	hgo	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
TLS3_k127_3087591_1	404589.Anae109_1682	6.979e-56	199.0	294ZR@1|root,2ZSCK@2|Bacteria	2|Bacteria	S	COG NOG27188 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3087591_0	290397.Adeh_4192	0.0	1082.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,2YU2E@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
TLS3_k127_3087591_2	404589.Anae109_4340	5.453e-40	154.0	COG3809@1|root,COG3809@2|Bacteria,1Q8Z4@1224|Proteobacteria,42UTF@68525|delta/epsilon subdivisions,2WXCZ@28221|Deltaproteobacteria,2Z0RF@29|Myxococcales	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
TLS3_k127_3087591_3	404589.Anae109_4339	2.46e-36	140.0	COG0721@1|root,COG0721@2|Bacteria,1QE6H@1224|Proteobacteria,42VPR@68525|delta/epsilon subdivisions,2WRP0@28221|Deltaproteobacteria,2YW6Q@29|Myxococcales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	iAF987.Gmet_0076	Glu-tRNAGln
TLS3_k127_3087591_4	404589.Anae109_4338	3.247e-12	70.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2YTXJ@29|Myxococcales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
TLS3_k127_3111873_2	404589.Anae109_1396	3.01e-155	507.0	COG0515@1|root,COG0515@2|Bacteria	404589.Anae109_1396|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
TLS3_k127_3111873_0	290397.Adeh_2473	1.674e-205	664.0	COG5360@1|root,COG5360@2|Bacteria,1MZ5X@1224|Proteobacteria,42SMC@68525|delta/epsilon subdivisions,2X5EG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
TLS3_k127_3111873_1	290397.Adeh_2474	1.086e-202	656.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WJEW@28221|Deltaproteobacteria,2YTWM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	capL	-	1.1.1.136,1.1.1.336	ko:K02472,ko:K02474,ko:K13015	ko00520,ko05111,map00520,map05111	-	R00421,R03317,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TLS3_k127_3111873_3	404589.Anae109_1393	5.932e-63	221.0	COG0312@1|root,COG0312@2|Bacteria,1Q3C0@1224|Proteobacteria,4393A@68525|delta/epsilon subdivisions,2X495@28221|Deltaproteobacteria,2YYIX@29|Myxococcales	28221|Deltaproteobacteria	S	peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
TLS3_k127_3168521_3	365528.KB891126_gene3240	1.968e-07	55.0	2CA5R@1|root,2Z81H@2|Bacteria,2GM6V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3168521_4	710686.Mycsm_03429	1.582e-05	54.0	COG4747@1|root,COG4747@2|Bacteria	2|Bacteria	-	-	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
TLS3_k127_3168521_0	290397.Adeh_3042	7.921e-93	311.0	COG0500@1|root,COG0500@2|Bacteria,1QW0F@1224|Proteobacteria,43C56@68525|delta/epsilon subdivisions,2X7FJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_3168521_1	404589.Anae109_1740	1.859e-86	289.0	COG0775@1|root,COG0775@2|Bacteria,1R9VR@1224|Proteobacteria	1224|Proteobacteria	F	Enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine	pfs	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
TLS3_k127_3175336_6	290397.Adeh_4356	1.365e-26	111.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,42SB8@68525|delta/epsilon subdivisions,2WPKF@28221|Deltaproteobacteria,2Z25M@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
TLS3_k127_3175336_2	404589.Anae109_4502	8.315e-118	392.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria,2YTSA@29|Myxococcales	28221|Deltaproteobacteria	D	NUBPL iron-transfer P-loop NTPase	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
TLS3_k127_3175336_1	290397.Adeh_4354	1.967e-123	402.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria,2YV3C@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
TLS3_k127_3175336_4	404589.Anae109_4500	1.088e-65	229.0	COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria,2YVIX@29|Myxococcales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
TLS3_k127_3175336_3	404589.Anae109_4499	1.272e-68	236.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
TLS3_k127_3175336_5	290397.Adeh_4351	1.043e-63	225.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,42U68@68525|delta/epsilon subdivisions,2WQJS@28221|Deltaproteobacteria,2Z301@29|Myxococcales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
TLS3_k127_3175336_0	404589.Anae109_4497	6.33e-197	616.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,2YUF7@29|Myxococcales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
TLS3_k127_3189830_8	290397.Adeh_3395	7.917e-52	186.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,42Q52@68525|delta/epsilon subdivisions,2WJ3S@28221|Deltaproteobacteria,2Z0HR@29|Myxococcales	28221|Deltaproteobacteria	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
TLS3_k127_3189830_4	290397.Adeh_3394	2.155e-93	325.0	COG1680@1|root,COG1680@2|Bacteria,1QUYZ@1224|Proteobacteria,42PUC@68525|delta/epsilon subdivisions,2WK0V@28221|Deltaproteobacteria,2Z110@29|Myxococcales	28221|Deltaproteobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_3189830_0	404589.Anae109_3458	1.049e-233	751.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,42NMY@68525|delta/epsilon subdivisions,2WJ8S@28221|Deltaproteobacteria,2YU74@29|Myxococcales	28221|Deltaproteobacteria	M	Mur ligase family, catalytic domain	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_3189830_3	404589.Anae109_3457	2.647e-94	329.0	COG3005@1|root,COG3005@2|Bacteria,1R03H@1224|Proteobacteria,43CQK@68525|delta/epsilon subdivisions,2X7Y1@28221|Deltaproteobacteria,2Z1GR@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
TLS3_k127_3189830_9	247634.GPB2148_2168	1.309e-21	103.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1J6KV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
TLS3_k127_3189830_5	290397.Adeh_3389	6.213e-92	307.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42V54@68525|delta/epsilon subdivisions,2WSDI@28221|Deltaproteobacteria,2YWJM@29|Myxococcales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
TLS3_k127_3189830_1	290397.Adeh_3389	3.561e-141	460.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42V54@68525|delta/epsilon subdivisions,2WSDI@28221|Deltaproteobacteria,2YWJM@29|Myxococcales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
TLS3_k127_3189830_2	290397.Adeh_3387	2.564e-104	345.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,2YVHS@29|Myxococcales	28221|Deltaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
TLS3_k127_3189830_7	404589.Anae109_3448	2.056e-56	203.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,42U06@68525|delta/epsilon subdivisions,2WQXU@28221|Deltaproteobacteria,2Z21I@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_3202078_3	404589.Anae109_0319	1.259e-120	392.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,42QF3@68525|delta/epsilon subdivisions,2WKPQ@28221|Deltaproteobacteria,2YYXT@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	6.1.1.17	ko:K01885,ko:K01894	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
TLS3_k127_3202078_5	404589.Anae109_0321	6.996e-64	235.0	COG4445@1|root,COG4445@2|Bacteria,1MVFE@1224|Proteobacteria,434T9@68525|delta/epsilon subdivisions,2WZ49@28221|Deltaproteobacteria,2Z1AM@29|Myxococcales	28221|Deltaproteobacteria	FJ	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)	-	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
TLS3_k127_3202078_2	404589.Anae109_0327	2.927e-144	478.0	COG0010@1|root,COG0010@2|Bacteria,1Q4HC@1224|Proteobacteria,42Z7A@68525|delta/epsilon subdivisions,2WU9B@28221|Deltaproteobacteria,2YUSB@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS3_k127_3202078_1	1144275.COCOR_02490	5.682e-158	528.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2WJ80@28221|Deltaproteobacteria,2YUN7@29|Myxococcales	28221|Deltaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
TLS3_k127_3202078_4	404589.Anae109_0329	1.175e-118	424.0	COG0515@1|root,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,4340I@68525|delta/epsilon subdivisions,2X4FB@28221|Deltaproteobacteria,2Z047@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TLS3_k127_3202078_6	378806.STAUR_5775	9.298e-43	179.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3202078_0	404589.Anae109_0503	1.197e-209	669.0	COG1572@1|root,COG1572@2|Bacteria,1N4MI@1224|Proteobacteria,42USE@68525|delta/epsilon subdivisions,2WQX2@28221|Deltaproteobacteria,2YVY2@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
TLS3_k127_3255680_1	404589.Anae109_4361	1.384e-44	179.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HWE_HK,HisKA,PAS_3,Response_reg
TLS3_k127_3255680_0	404589.Anae109_1395	2.325e-211	674.0	COG1572@1|root,COG1572@2|Bacteria,1N4MI@1224|Proteobacteria,42USE@68525|delta/epsilon subdivisions,2WQX2@28221|Deltaproteobacteria,2YVY2@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
TLS3_k127_3266392_6	290397.Adeh_1388	3.534e-51	195.0	COG1843@1|root,COG3656@1|root,COG1843@2|Bacteria,COG3656@2|Bacteria,1MXCG@1224|Proteobacteria,42U4T@68525|delta/epsilon subdivisions,2WQ5B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
TLS3_k127_3266392_1	290397.Adeh_1387	1.979e-158	525.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42NGP@68525|delta/epsilon subdivisions,2WIZN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Flagellar hook protein FlgE	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
TLS3_k127_3266392_10	644966.Tmar_0986	1.35e-09	66.0	COG1582@1|root,COG1582@2|Bacteria,1VKHB@1239|Firmicutes,24RWI@186801|Clostridia	186801|Clostridia	N	PFAM flagellar FlbD family protein	flbD	-	-	ko:K02385	-	-	-	-	ko00000,ko02035	-	-	-	FlbD
TLS3_k127_3266392_2	290397.Adeh_1385	1.186e-98	330.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42PR1@68525|delta/epsilon subdivisions,2WIQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM MotA TolQ ExbB proton channel	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
TLS3_k127_3266392_4	290397.Adeh_1384	7.038e-81	276.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42Q7D@68525|delta/epsilon subdivisions,2WKIT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
TLS3_k127_3266392_3	290397.Adeh_2430	2.071e-81	280.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,42KZF@68525|delta/epsilon subdivisions,2WSRV@28221|Deltaproteobacteria,2YWHX@29|Myxococcales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_3266392_5	285514.JNWO01000007_gene3110	5.709e-79	297.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria	201174|Actinobacteria	C	NADPH quinone reductase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_3266392_0	404589.Anae109_1447	5.282e-281	882.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2WIWF@28221|Deltaproteobacteria,2YUMB@29|Myxococcales	28221|Deltaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
TLS3_k127_3266392_7	404589.Anae109_1445	2.199e-46	170.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42M5U@68525|delta/epsilon subdivisions,2X5HK@28221|Deltaproteobacteria,2Z35S@29|Myxococcales	28221|Deltaproteobacteria	H	MoeA C-terminal region (domain IV)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
TLS3_k127_3284407_0	404589.Anae109_4318	1.102e-191	602.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria,2YTT7@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
TLS3_k127_3284407_1	290397.Adeh_4173	4.574e-136	455.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,2YUE2@29|Myxococcales	28221|Deltaproteobacteria	H	DAHP synthetase I family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
TLS3_k127_3284407_3	290397.Adeh_4172	6.874e-67	245.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,42SN2@68525|delta/epsilon subdivisions,2WPT4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
TLS3_k127_3284407_2	404589.Anae109_4089	6.802e-94	314.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
TLS3_k127_3284758_5	404589.Anae109_0159	1.479e-112	364.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
TLS3_k127_3284758_4	404589.Anae109_0163	8.092e-113	370.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WKPK@28221|Deltaproteobacteria,2Z316@29|Myxococcales	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
TLS3_k127_3284758_6	404589.Anae109_0164	1.315e-56	217.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,42TAG@68525|delta/epsilon subdivisions,2X5C6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_3284758_1	404589.Anae109_0165	3.508e-148	491.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,2YUTZ@29|Myxococcales	28221|Deltaproteobacteria	M	Mannose-6-phosphate isomerase	manAC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
TLS3_k127_3284758_0	1297742.A176_01576	9.098e-178	569.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2WITH@28221|Deltaproteobacteria,2YUC2@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	algC	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TLS3_k127_3284758_3	290397.Adeh_0161	1.642e-124	406.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,42S50@68525|delta/epsilon subdivisions,2X5NZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GK	PFAM ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
TLS3_k127_3284758_2	404589.Anae109_0171	2.641e-129	424.0	COG1293@1|root,COG1293@2|Bacteria,1P028@1224|Proteobacteria,42MKF@68525|delta/epsilon subdivisions,2X6XB@28221|Deltaproteobacteria,2Z3DG@29|Myxococcales	28221|Deltaproteobacteria	K	Domain of unknown function (DUF814)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
TLS3_k127_3303654_3	404589.Anae109_2104	2.547e-106	360.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42SP5@68525|delta/epsilon subdivisions,2WP39@28221|Deltaproteobacteria,2YUQU@29|Myxococcales	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
TLS3_k127_3303654_0	404589.Anae109_2106	3.515e-231	728.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	pfam abc1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH,WaaY
TLS3_k127_3303654_1	404589.Anae109_0081	1.412e-227	712.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria	1224|Proteobacteria	C	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_3303654_2	404589.Anae109_0082	1.171e-176	566.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	peptidase, M16	MA20_05660	-	-	ko:K07263,ko:K07623	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_331082_4	404589.Anae109_0014	4.718e-51	209.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
TLS3_k127_331082_0	404589.Anae109_0013	0.0	1535.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
TLS3_k127_331082_1	290397.Adeh_0011	2.838e-139	449.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,42NIA@68525|delta/epsilon subdivisions,2WM87@28221|Deltaproteobacteria,2YUDN@29|Myxococcales	28221|Deltaproteobacteria	HJ	Belongs to the RimK family	rimK	-	6.3.2.32	ko:K05844,ko:K14940	ko00680,ko01120,map00680,map01120	-	R09401	RC00064,RC00090	ko00000,ko00001,ko01000,ko03009	-	-	-	RimK
TLS3_k127_331082_3	404589.Anae109_0011	3.773e-61	219.0	COG2761@1|root,COG2761@2|Bacteria	2|Bacteria	Q	protein disulfide oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
TLS3_k127_331082_2	290397.Adeh_0032	9.464e-129	424.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
TLS3_k127_331082_5	404589.Anae109_0034	5.539e-06	52.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_bact_N
TLS3_k127_3322374_4	404589.Anae109_1905	5.784e-35	139.0	2DBB1@1|root,2Z854@2|Bacteria	2|Bacteria	S	membrane	yxxB	-	-	-	-	-	-	-	-	-	-	-	DUF1206
TLS3_k127_3322374_1	290397.Adeh_1162	2.596e-169	540.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,42MY6@68525|delta/epsilon subdivisions,2WME2@28221|Deltaproteobacteria,2YWHE@29|Myxococcales	28221|Deltaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_3322374_2	1210884.HG799466_gene13015	4.378e-99	335.0	COG0053@1|root,COG0053@2|Bacteria,2IY05@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
TLS3_k127_3322374_5	404589.Anae109_0791	9.947e-31	129.0	COG1846@1|root,COG1846@2|Bacteria,1RKAV@1224|Proteobacteria,42VFQ@68525|delta/epsilon subdivisions,2WRWP@28221|Deltaproteobacteria,2YVC3@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	marR	-	-	-	-	-	-	-	-	-	-	-	MarR_2
TLS3_k127_3322374_0	290397.Adeh_2130	0.0	1569.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,42PYN@68525|delta/epsilon subdivisions,2WS4X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
TLS3_k127_3322374_3	404589.Anae109_4127	1.802e-67	246.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,42MYB@68525|delta/epsilon subdivisions,2WIUY@28221|Deltaproteobacteria,2YU5E@29|Myxococcales	28221|Deltaproteobacteria	C	acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS3_k127_3383511_3	756067.MicvaDRAFT_3373	1.878e-87	302.0	COG1404@1|root,COG2931@1|root,COG3210@1|root,COG3391@1|root,COG4257@1|root,COG4625@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4257@2|Bacteria,COG4625@2|Bacteria,1GR3A@1117|Cyanobacteria	1117|Cyanobacteria	OQ	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,HemolysinCabind
TLS3_k127_3383511_0	290397.Adeh_4176	1.06e-160	524.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,42MSY@68525|delta/epsilon subdivisions,2WJXR@28221|Deltaproteobacteria,2YVAN@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	mnaA	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
TLS3_k127_3383511_2	404589.Anae109_4319	2.436e-106	349.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,2YYFF@29|Myxococcales	28221|Deltaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
TLS3_k127_3383511_1	404589.Anae109_4318	9.37e-142	451.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria,2YTT7@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
TLS3_k127_3442728_4	404589.Anae109_3083	2.868e-86	298.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,42SGK@68525|delta/epsilon subdivisions,2WPDI@28221|Deltaproteobacteria,2YVW1@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_4,Abhydrolase_5,DLH
TLS3_k127_3442728_6	290397.Adeh_1657	5.473e-36	145.0	COG1051@1|root,COG1051@2|Bacteria,1QUNH@1224|Proteobacteria,43C4F@68525|delta/epsilon subdivisions,2WS06@28221|Deltaproteobacteria,2Z2IP@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
TLS3_k127_3442728_2	404589.Anae109_2153	3.603e-111	369.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,42V3F@68525|delta/epsilon subdivisions,2WR8K@28221|Deltaproteobacteria,2YVGH@29|Myxococcales	28221|Deltaproteobacteria	S	PQQ enzyme repeat	yfgL	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
TLS3_k127_3442728_5	290397.Adeh_1655	6.369e-64	228.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	CP_0079	-	-	ko:K15368	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_21,TPR_6
TLS3_k127_3442728_0	290397.Adeh_1654	1.265e-211	683.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2WISS@28221|Deltaproteobacteria,2YU6J@29|Myxococcales	28221|Deltaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
TLS3_k127_3442728_1	404589.Anae109_2156	5.264e-147	470.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2WJC8@28221|Deltaproteobacteria,2YYQ7@29|Myxococcales	28221|Deltaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
TLS3_k127_3442728_3	290397.Adeh_1652	2.519e-93	309.0	COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,42NWS@68525|delta/epsilon subdivisions,2X60R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
TLS3_k127_3521054_2	290397.Adeh_4135	7.749e-181	581.0	COG1175@1|root,COG1175@2|Bacteria,1MXKR@1224|Proteobacteria,42UM4@68525|delta/epsilon subdivisions,2WQPJ@28221|Deltaproteobacteria,2YUAR@29|Myxococcales	28221|Deltaproteobacteria	P	Sugar ABC transporter permease	malF	-	-	ko:K10109,ko:K15770,ko:K15771	ko02010,map02010	M00194,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22	-	-	BPD_transp_1,SBP_bac_8
TLS3_k127_3521054_3	290397.Adeh_4134	2.86e-132	453.0	COG3833@1|root,COG3833@2|Bacteria,1QA3Z@1224|Proteobacteria,42R4X@68525|delta/epsilon subdivisions,2WN1E@28221|Deltaproteobacteria,2YU8W@29|Myxococcales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10110,ko:K15772	ko02010,map02010	M00194,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22	-	-	BPD_transp_1
TLS3_k127_3521054_5	290397.Adeh_4133	7.291e-96	321.0	COG4945@1|root,COG4945@2|Bacteria	2|Bacteria	G	C-terminal binding-module, SLH-like, of glucodextranase	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Cu_amine_oxidN1,Glucodextran_B,Glucodextran_C,Glucodextran_N,Glyco_hydro_15,Glyco_hydro_49,Glyco_hydro_49N
TLS3_k127_3521054_0	215803.DB30_1690	2.437e-282	886.0	2CB5G@1|root,33TBA@2|Bacteria,1NS5Z@1224|Proteobacteria,439KD@68525|delta/epsilon subdivisions,2X4X3@28221|Deltaproteobacteria,2YZSA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3521054_6	215803.DB30_1689	6.894e-64	247.0	COG4945@1|root,COG4945@2|Bacteria,1NYP6@1224|Proteobacteria,4394H@68525|delta/epsilon subdivisions,2X4AK@28221|Deltaproteobacteria,2YYMF@29|Myxococcales	28221|Deltaproteobacteria	G	C-terminal binding-module, SLH-like, of glucodextranase	-	-	-	-	-	-	-	-	-	-	-	-	Glucodextran_C
TLS3_k127_3521054_1	1144275.COCOR_00327	2.329e-195	633.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,43740@68525|delta/epsilon subdivisions,2X1YD@28221|Deltaproteobacteria,2YWVB@29|Myxococcales	28221|Deltaproteobacteria	G	Alpha-amylase domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
TLS3_k127_3521054_4	649638.Trad_2634	2.614e-110	367.0	COG0702@1|root,COG0702@2|Bacteria,1WJH3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,NmrA
TLS3_k127_3534744_7	767434.Fraau_2073	1.347e-06	53.0	COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,1S8TQ@1236|Gammaproteobacteria,1X88V@135614|Xanthomonadales	135614|Xanthomonadales	N	flagellar protein FliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
TLS3_k127_3534744_4	404589.Anae109_2432	5.39e-39	160.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,42RZK@68525|delta/epsilon subdivisions,2WQ3C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	TIGRFAM Molybdopterin-guanine dinucleotide biosynthesis protein B	-	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
TLS3_k127_3534744_0	404589.Anae109_2433	3.086e-120	399.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42M5U@68525|delta/epsilon subdivisions,2WJ06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
TLS3_k127_3534744_1	290397.Adeh_1333	1.704e-113	391.0	COG0664@1|root,COG0664@2|Bacteria,1QAZ0@1224|Proteobacteria,43E4R@68525|delta/epsilon subdivisions,2WZQH@28221|Deltaproteobacteria,2Z2IM@29|Myxococcales	28221|Deltaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
TLS3_k127_3534744_6	1278073.MYSTI_03420	2.226e-08	58.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria	1224|Proteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	GO:0003674,GO:0005215	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
TLS3_k127_3534744_5	1278073.MYSTI_07683	2.327e-11	76.0	COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria	1224|Proteobacteria	T	dnak suppressor protein	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
TLS3_k127_3534744_2	290397.Adeh_1330	2.428e-52	191.0	COG0517@1|root,COG0517@2|Bacteria,1N0EB@1224|Proteobacteria,42W96@68525|delta/epsilon subdivisions,2WRIB@28221|Deltaproteobacteria,2YVSI@29|Myxococcales	28221|Deltaproteobacteria	S	CBS domain	-	-	-	ko:K04767,ko:K07168,ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
TLS3_k127_3534744_3	483219.LILAB_29365	3.335e-51	184.0	COG0642@1|root,COG2205@2|Bacteria,1QX6V@1224|Proteobacteria,43AID@68525|delta/epsilon subdivisions,2X5YM@28221|Deltaproteobacteria,2YUUS@29|Myxococcales	28221|Deltaproteobacteria	T	Protoglobin	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Protoglobin
TLS3_k127_3549081_3	290397.Adeh_0004	7.642e-38	145.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,2YU54@29|Myxococcales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
TLS3_k127_3549081_1	404589.Anae109_0003	9.075e-165	525.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,42SYJ@68525|delta/epsilon subdivisions,2WP80@28221|Deltaproteobacteria,2YV1Z@29|Myxococcales	28221|Deltaproteobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
TLS3_k127_3549081_0	290397.Adeh_0002	4.656e-166	529.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2WJZM@28221|Deltaproteobacteria,2YUS5@29|Myxococcales	28221|Deltaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
TLS3_k127_3549081_2	515635.Dtur_0001	3.872e-101	347.0	COG0593@1|root,COG0593@2|Bacteria	2|Bacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
TLS3_k127_3549081_4	404589.Anae109_4508	7.589e-28	131.0	COG0594@1|root,COG0594@2|Bacteria,1NGQJ@1224|Proteobacteria,42VBC@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
TLS3_k127_3549081_5	1120934.KB894421_gene2520	3.866e-24	102.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4E5Q0@85010|Pseudonocardiales	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
TLS3_k127_3549081_6	644282.Deba_0273	4.089e-05	48.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
TLS3_k127_3583115_1	404589.Anae109_4398	4.072e-150	481.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
TLS3_k127_3583115_3	338963.Pcar_1994	2.688e-32	144.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43RYA@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	gnfM	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_3583115_2	404589.Anae109_4399	1.586e-139	459.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YU4Y@29|Myxococcales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	gnfM	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_3583115_0	404589.Anae109_4400	5.131e-254	788.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2YUPP@29|Myxococcales	28221|Deltaproteobacteria	H	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
TLS3_k127_3606758_0	243231.GSU1538	5.395e-108	364.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N38@68525|delta/epsilon subdivisions,2WK56@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Cytochrom_C
TLS3_k127_3606758_1	937777.Deipe_1800	3.766e-05	56.0	COG2197@1|root,COG2197@2|Bacteria,1WIZJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_3606758_2	1120949.KB903310_gene882	0.0005876	47.0	COG2197@1|root,COG2197@2|Bacteria,2GNMH@201174|Actinobacteria,4DDFV@85008|Micromonosporales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_3611441_0	1242864.D187_009606	1.386e-150	491.0	COG4277@1|root,COG4277@2|Bacteria,1MVCV@1224|Proteobacteria,42NNA@68525|delta/epsilon subdivisions,2WTR9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Helix-hairpin-helix DNA-binding motif class 1	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
TLS3_k127_3611441_1	1254432.SCE1572_10110	2.657e-132	440.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,42ZZ6@68525|delta/epsilon subdivisions,2WV5A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4130,UDG
TLS3_k127_3627184_4	1144275.COCOR_00539	3.931e-41	169.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	DUF3365,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_3627184_1	404589.Anae109_3565	7.039e-235	733.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2WJWP@28221|Deltaproteobacteria,2YX7S@29|Myxococcales	28221|Deltaproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
TLS3_k127_3627184_0	404589.Anae109_3566	3.283e-254	790.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,42M9Z@68525|delta/epsilon subdivisions,2WIYZ@28221|Deltaproteobacteria,2YU0Z@29|Myxococcales	28221|Deltaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
TLS3_k127_3627184_2	404589.Anae109_3567	1.402e-83	292.0	COG1647@1|root,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,42NBK@68525|delta/epsilon subdivisions,2WIUP@28221|Deltaproteobacteria,2Z262@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,Hydrolase_4
TLS3_k127_3627184_5	404589.Anae109_3568	1.801e-35	150.0	2E4KV@1|root,32ZFU@2|Bacteria,1NPD5@1224|Proteobacteria,42XQS@68525|delta/epsilon subdivisions,2WTAP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
TLS3_k127_3627184_3	290397.Adeh_0301	1.339e-64	239.0	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,4301R@68525|delta/epsilon subdivisions,2WVCA@28221|Deltaproteobacteria,2YYZK@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_3627184_6	1144275.COCOR_00920	2.6e-27	129.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YY7A@29|Myxococcales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	ko:K07713,ko:K07714,ko:K07715	ko02020,ko02024,map02020,map02024	M00499,M00500,M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_3632664_7	1278073.MYSTI_07598	1.518e-63	234.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	asgD	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
TLS3_k127_3632664_1	404589.Anae109_3197	1.372e-238	748.0	COG2855@1|root,COG2855@2|Bacteria,1MVPE@1224|Proteobacteria,42NT6@68525|delta/epsilon subdivisions,2WJ9R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	family UPF0324	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
TLS3_k127_3632664_4	290397.Adeh_3154	8.691e-179	570.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WTQ2@28221|Deltaproteobacteria,2Z2X5@29|Myxococcales	28221|Deltaproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	-	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,TP_methylase
TLS3_k127_3632664_0	404589.Anae109_3604	2.904e-244	770.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42Q77@68525|delta/epsilon subdivisions,2WK3N@28221|Deltaproteobacteria,2YU8G@29|Myxococcales	28221|Deltaproteobacteria	C	Sulfite reductase	-	-	1.7.7.1,1.8.1.2,1.8.7.1	ko:K00366,ko:K00381,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
TLS3_k127_3632664_3	404589.Anae109_3605	2.5e-211	663.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2YTVW@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_3632664_9	404589.Anae109_3606	9.646e-37	157.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	2.7.7.80,2.8.1.11	ko:K03636,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiS
TLS3_k127_3632664_2	404589.Anae109_3607	2.373e-215	675.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,1MW7H@1224|Proteobacteria,42NEC@68525|delta/epsilon subdivisions,2WK08@28221|Deltaproteobacteria,2YUA5@29|Myxococcales	28221|Deltaproteobacteria	HP	domain protein	moeB1	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
TLS3_k127_3632664_6	404589.Anae109_3608	1.267e-141	464.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,2YWJD@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK-1	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_3632664_5	404589.Anae109_3609	3.12e-162	518.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42M6M@68525|delta/epsilon subdivisions,2WIQM@28221|Deltaproteobacteria,2YU2W@29|Myxococcales	28221|Deltaproteobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	cysM	-	2.5.1.47,6.1.1.16	ko:K01738,ko:K01883,ko:K12339	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,PALP,tRNA-synt_1e
TLS3_k127_3632664_8	404589.Anae109_3610	2.728e-55	212.0	COG1310@1|root,COG1310@2|Bacteria,1PBUE@1224|Proteobacteria,435H8@68525|delta/epsilon subdivisions,2WZUV@28221|Deltaproteobacteria,2Z2SW@29|Myxococcales	28221|Deltaproteobacteria	S	Prokaryotic homologs of the JAB domain	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
TLS3_k127_3632664_10	290397.Adeh_0300	1.826e-21	98.0	COG4633@1|root,COG4633@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,DsbD_2,HMA
TLS3_k127_3645471_4	1125863.JAFN01000001_gene1462	1.185e-205	667.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
TLS3_k127_3645471_12	290397.Adeh_2635	4.811e-43	177.0	COG0745@1|root,COG0745@2|Bacteria,1NBDV@1224|Proteobacteria,42UVC@68525|delta/epsilon subdivisions,2WQ45@28221|Deltaproteobacteria,2Z1WY@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_3645471_7	290397.Adeh_2634	2.635e-115	386.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CCF@68525|delta/epsilon subdivisions,2X60X@28221|Deltaproteobacteria,2Z384@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_3645471_5	290397.Adeh_2625	1.763e-164	528.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
TLS3_k127_3645471_9	404589.Anae109_2588	2.508e-111	382.0	COG1216@1|root,COG1216@2|Bacteria,1QX3U@1224|Proteobacteria,42RP8@68525|delta/epsilon subdivisions,2WNF5@28221|Deltaproteobacteria,2Z30X@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
TLS3_k127_3645471_11	404589.Anae109_2587	1.319e-66	233.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,42TIP@68525|delta/epsilon subdivisions,2WQA8@28221|Deltaproteobacteria,2YZB0@29|Myxococcales	28221|Deltaproteobacteria	U	UPF0056 inner membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
TLS3_k127_3645471_1	404589.Anae109_2586	1.837e-288	895.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42P0M@68525|delta/epsilon subdivisions,2WJMC@28221|Deltaproteobacteria,2YXRV@29|Myxococcales	28221|Deltaproteobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_3645471_0	290397.Adeh_2618	0.0	1069.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2YUGE@29|Myxococcales	28221|Deltaproteobacteria	J	Elongation factor G, domain IV	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
TLS3_k127_3645471_2	290397.Adeh_2617	1.449e-265	829.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WJ7M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS3_k127_3645471_10	404589.Anae109_2583	2.47e-98	336.0	COG0613@1|root,COG0613@2|Bacteria,1Q692@1224|Proteobacteria,432NB@68525|delta/epsilon subdivisions,2WXVS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3645471_3	290397.Adeh_2615	7.775e-207	649.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2WJ6Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Three-deoxy-D-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
TLS3_k127_3645471_8	290397.Adeh_2614	5.35e-115	414.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42UES@68525|delta/epsilon subdivisions,2WQD1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
TLS3_k127_3645471_6	404589.Anae109_2580	2.356e-124	421.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2WNJ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
TLS3_k127_3645471_13	404589.Anae109_2579	3.195e-29	133.0	COG1560@1|root,COG1560@2|Bacteria,1R03A@1224|Proteobacteria,43CQI@68525|delta/epsilon subdivisions,2X7XZ@28221|Deltaproteobacteria,2Z27Y@29|Myxococcales	28221|Deltaproteobacteria	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
TLS3_k127_3656842_9	378806.STAUR_5006	1.991e-10	64.0	COG0457@1|root,COG0457@2|Bacteria,1MZGK@1224|Proteobacteria,42US4@68525|delta/epsilon subdivisions,2X72T@28221|Deltaproteobacteria,2YVP7@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
TLS3_k127_3656842_7	404589.Anae109_2463	3.25e-27	115.0	COG1426@1|root,COG1426@2|Bacteria,1PR8V@1224|Proteobacteria	1224|Proteobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
TLS3_k127_3656842_4	290397.Adeh_1303	1.071e-86	304.0	COG1381@1|root,COG1381@2|Bacteria,1RIBW@1224|Proteobacteria,42PUE@68525|delta/epsilon subdivisions,2WK4W@28221|Deltaproteobacteria,2YVXU@29|Myxococcales	28221|Deltaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
TLS3_k127_3656842_2	290397.Adeh_1305	8.987e-179	563.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,42MNQ@68525|delta/epsilon subdivisions,2WJJW@28221|Deltaproteobacteria,2YTSG@29|Myxococcales	28221|Deltaproteobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_2942	tRNA-synt_2e
TLS3_k127_3656842_1	290397.Adeh_1306	2.206e-300	936.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2WJIT@28221|Deltaproteobacteria,2YUNH@29|Myxococcales	28221|Deltaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
TLS3_k127_3656842_8	525904.Tter_1427	8.696e-11	75.0	COG1716@1|root,COG1716@2|Bacteria,2NQ4X@2323|unclassified Bacteria	2|Bacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
TLS3_k127_3656842_0	290397.Adeh_1310	0.0	1279.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2YXGJ@29|Myxococcales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
TLS3_k127_3656842_6	404589.Anae109_2453	1.283e-48	183.0	COG3599@1|root,COG3599@2|Bacteria,1NCAV@1224|Proteobacteria,42VH6@68525|delta/epsilon subdivisions,2WS27@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM DivIVA family protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
TLS3_k127_3656842_10	317936.Nos7107_1412	2.147e-10	66.0	COG0642@1|root,COG0784@1|root,COG3447@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3447@2|Bacteria,1GD81@1117|Cyanobacteria	1117|Cyanobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1,PAS_4,Response_reg
TLS3_k127_3663432_2	404589.Anae109_2735	1.882e-100	329.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,2YXTZ@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_3663432_5	404589.Anae109_2734	1.172e-64	233.0	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,42SAN@68525|delta/epsilon subdivisions,2WP1V@28221|Deltaproteobacteria,2Z0C3@29|Myxococcales	28221|Deltaproteobacteria	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1604	LacAB_rpiB
TLS3_k127_3663432_0	290397.Adeh_2744	2.706e-240	746.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,2YYIF@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
TLS3_k127_3663432_4	404589.Anae109_2732	2.193e-66	233.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,42SJP@68525|delta/epsilon subdivisions,2WPK0@28221|Deltaproteobacteria,2YVAV@29|Myxococcales	28221|Deltaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
TLS3_k127_3663432_1	290397.Adeh_2742	7.055e-157	512.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2WIP2@28221|Deltaproteobacteria,2YUVJ@29|Myxococcales	28221|Deltaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1624	RibD_C,dCMP_cyt_deam_1
TLS3_k127_3663432_6	395964.KE386496_gene1360	5.753e-11	74.0	COG3049@1|root,COG3049@2|Bacteria,1RC5C@1224|Proteobacteria,2U6YD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3663432_3	404589.Anae109_2730	3.301e-95	318.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2WNK6@28221|Deltaproteobacteria,2YVMJ@29|Myxococcales	28221|Deltaproteobacteria	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
TLS3_k127_3667690_6	420662.Mpe_A3601	0.0003443	44.0	2DZV2@1|root,32VJS@2|Bacteria,1R36S@1224|Proteobacteria,2WIFX@28216|Betaproteobacteria,1KMT1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3667690_5	926569.ANT_20470	2.651e-05	53.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
TLS3_k127_3667690_0	404589.Anae109_4379	2.809e-170	542.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2YWPQ@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the radical SAM superfamily. RlmN family	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
TLS3_k127_3667690_3	1122185.N792_12105	1.271e-33	138.0	2E3HM@1|root,32YG7@2|Bacteria,1NM0U@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3667690_1	290397.Adeh_4228	5.301e-159	519.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2WM6R@28221|Deltaproteobacteria,2YZCT@29|Myxococcales	28221|Deltaproteobacteria	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
TLS3_k127_3667690_2	290397.Adeh_4227	1.908e-81	280.0	COG1392@1|root,COG1392@2|Bacteria,1R4SP@1224|Proteobacteria,42SPV@68525|delta/epsilon subdivisions,2WPTH@28221|Deltaproteobacteria,2Z0HM@29|Myxococcales	28221|Deltaproteobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
TLS3_k127_3667690_4	404589.Anae109_4371	3.149e-12	67.0	COG1544@1|root,COG1544@2|Bacteria	2|Bacteria	J	regulation of translation	raiA	-	-	ko:K05809	-	-	-	-	ko00000,ko03009	-	-	-	CSD,Ribosomal_S30AE
TLS3_k127_3705693_4	404589.Anae109_2188	0.0001502	50.0	COG0642@1|root,COG3284@1|root,COG2205@2|Bacteria,COG3284@2|Bacteria,1NRP8@1224|Proteobacteria,43E87@68525|delta/epsilon subdivisions,2X7N1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS
TLS3_k127_3705693_2	378806.STAUR_4037	3.937e-18	89.0	2AGAC@1|root,316FV@2|Bacteria,1PXI4@1224|Proteobacteria,434KJ@68525|delta/epsilon subdivisions,2X8XK@28221|Deltaproteobacteria,2Z0FD@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3705693_3	240015.ACP_0464	1.286e-15	84.0	COG1259@1|root,COG1259@2|Bacteria,3Y4QD@57723|Acidobacteria,2JJ7J@204432|Acidobacteriia	204432|Acidobacteriia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
TLS3_k127_3705693_0	404589.Anae109_0535	8.431e-142	480.0	COG3188@1|root,COG3188@2|Bacteria,1MWV6@1224|Proteobacteria,42WF9@68525|delta/epsilon subdivisions,2WRD4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Outer membrane usher protein	csuD	-	-	ko:K07347	ko05133,map05133	-	-	-	ko00000,ko00001,ko02000,ko02035,ko02044	1.B.11.3	-	-	Usher
TLS3_k127_3705693_1	290397.Adeh_3600	4.435e-52	191.0	COG3121@1|root,COG3121@2|Bacteria	2|Bacteria	NU	pilus organization	csuC	-	-	ko:K07346	-	-	-	-	ko00000,ko02035,ko02044,ko03110	-	-	-	PapD_N
TLS3_k127_3729224_6	404589.Anae109_3630	1.944e-71	246.0	COG3059@1|root,COG3059@2|Bacteria,1RBVI@1224|Proteobacteria,43A7Q@68525|delta/epsilon subdivisions,2X99M@28221|Deltaproteobacteria,2Z2SB@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF417	-	-	-	-	-	-	-	-	-	-	-	-	DUF417
TLS3_k127_3729224_4	251221.35211725	7.061e-126	414.0	COG0346@1|root,COG0346@2|Bacteria,1G29P@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_3729224_5	861299.J421_1875	5.642e-85	290.0	COG0662@1|root,COG3193@1|root,COG0662@2|Bacteria,COG3193@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Cupin_2,Haem_degrading
TLS3_k127_3729224_1	861299.J421_1876	5.896e-204	650.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
TLS3_k127_3729224_0	671143.DAMO_0621	0.0	1354.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	Glyco_hydro_63
TLS3_k127_3729224_2	251221.35211731	9.935e-161	514.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	gcd	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
TLS3_k127_3729224_3	234267.Acid_3143	6.388e-159	555.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	glgX	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
TLS3_k127_3744140_0	290397.Adeh_1435	9.323e-123	398.0	COG0697@1|root,COG0697@2|Bacteria,1RBQS@1224|Proteobacteria,42U3T@68525|delta/epsilon subdivisions,2WQAP@28221|Deltaproteobacteria,2Z2VR@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_3744140_1	404589.Anae109_0815	2.268e-72	258.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,42TPX@68525|delta/epsilon subdivisions,2WNCR@28221|Deltaproteobacteria,2Z386@29|Myxococcales	28221|Deltaproteobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
TLS3_k127_3744140_5	404589.Anae109_3277	6.513e-26	121.0	COG0745@1|root,COG0745@2|Bacteria	404589.Anae109_3277|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3744140_3	1121440.AUMA01000012_gene1350	2.302e-43	163.0	COG3238@1|root,COG3238@2|Bacteria,1N6ZC@1224|Proteobacteria,42TS3@68525|delta/epsilon subdivisions,2WQN1@28221|Deltaproteobacteria,2MCJM@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
TLS3_k127_3744140_2	290397.Adeh_1220	1.728e-66	231.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,42MCS@68525|delta/epsilon subdivisions,2WRZW@28221|Deltaproteobacteria,2YWS5@29|Myxococcales	28221|Deltaproteobacteria	O	Peptidyl-prolyl cis-trans	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
TLS3_k127_3744140_4	443255.SCLAV_0317	8.725e-30	121.0	COG5298@1|root,COG5298@2|Bacteria,2GVU1@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2334)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2334
TLS3_k127_3748444_8	404589.Anae109_1464	7.313e-33	128.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,42SD9@68525|delta/epsilon subdivisions,2WPPN@28221|Deltaproteobacteria,2YVKY@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3200	CTP_transf_like
TLS3_k127_3748444_7	378806.STAUR_6783	1.144e-49	188.0	COG3137@1|root,COG3137@2|Bacteria,1Q2RW@1224|Proteobacteria,438DI@68525|delta/epsilon subdivisions,2X3NN@28221|Deltaproteobacteria,2YWPE@29|Myxococcales	28221|Deltaproteobacteria	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
TLS3_k127_3748444_3	483219.LILAB_04045	4.505e-98	351.0	COG0784@1|root,COG1716@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG1716@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PGC@68525|delta/epsilon subdivisions,2WKHK@28221|Deltaproteobacteria,2Z2WB@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_3
TLS3_k127_3748444_6	404589.Anae109_4073	2.373e-50	186.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,42SK2@68525|delta/epsilon subdivisions,2WPB3@28221|Deltaproteobacteria,2Z0CU@29|Myxococcales	28221|Deltaproteobacteria	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	bfr	GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
TLS3_k127_3748444_4	404589.Anae109_1317	4.399e-94	312.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RQR@68525|delta/epsilon subdivisions,2WNTF@28221|Deltaproteobacteria,2Z0PC@29|Myxococcales	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
TLS3_k127_3748444_5	1242864.D187_010102	1.374e-73	280.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42R06@68525|delta/epsilon subdivisions,2X1UD@28221|Deltaproteobacteria,2YZ3C@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
TLS3_k127_3748444_2	76114.ebA4892	5.823e-151	484.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHGM@28216|Betaproteobacteria,2KVQ7@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
TLS3_k127_3748444_0	1121033.AUCF01000008_gene5646	3.34e-177	576.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TSTS@28211|Alphaproteobacteria,2JPDF@204441|Rhodospirillales	204441|Rhodospirillales	P	COG1178 ABC-type Fe3 transport system, permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
TLS3_k127_3748444_1	640081.Dsui_2928	2.306e-153	492.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2VHI6@28216|Betaproteobacteria,2KVDU@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
TLS3_k127_3756710_3	404589.Anae109_1724	9.413e-20	91.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,42Q75@68525|delta/epsilon subdivisions,2WMDY@28221|Deltaproteobacteria,2YU11@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD DEAH box	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
TLS3_k127_3756710_0	404589.Anae109_1725	6.828e-106	353.0	COG0266@1|root,COG0266@2|Bacteria,1N1J5@1224|Proteobacteria,433TA@68525|delta/epsilon subdivisions,2X3D6@28221|Deltaproteobacteria,2YVHV@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the FPG family	-	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
TLS3_k127_3756710_1	290397.Adeh_2367	1.879e-50	187.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807,DUF4097,PA14
TLS3_k127_3756710_2	1408445.JHXP01000009_gene2783	2.465e-34	148.0	COG5492@1|root,COG5492@2|Bacteria,1PZBJ@1224|Proteobacteria,1SZNY@1236|Gammaproteobacteria,1JFM8@118969|Legionellales	1224|Proteobacteria	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF3494
TLS3_k127_3786911_1	290397.Adeh_4295	7.025e-220	706.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MA3@68525|delta/epsilon subdivisions,2WM1D@28221|Deltaproteobacteria,2Z1MB@29|Myxococcales	28221|Deltaproteobacteria	H	DegT/DnrJ/EryC1/StrS aminotransferase family	ddhC	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_3786911_3	583355.Caka_0401	2.57e-119	406.0	COG0451@1|root,COG0451@2|Bacteria,46UP7@74201|Verrucomicrobia,3K999@414999|Opitutae	414999|Opitutae	GM	Polysaccharide biosynthesis protein	-	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
TLS3_k127_3786911_2	290397.Adeh_4297	3.577e-152	483.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MCW@68525|delta/epsilon subdivisions,2WIYK@28221|Deltaproteobacteria,2YZY8@29|Myxococcales	28221|Deltaproteobacteria	JM	Nucleotidyl transferase	ddhA	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
TLS3_k127_3786911_6	404589.Anae109_3626	2.024e-74	260.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42N4Z@68525|delta/epsilon subdivisions,2WIKW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrB	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
TLS3_k127_3786911_9	1198114.AciX9_1290	2.777e-45	177.0	COG5429@1|root,COG5429@2|Bacteria,3Y4TV@57723|Acidobacteria,2JJFF@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
TLS3_k127_3786911_0	290397.Adeh_2061	3.341e-314	998.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YU05@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
TLS3_k127_3786911_5	404589.Anae109_1743	4.201e-82	275.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,42SIR@68525|delta/epsilon subdivisions,2WPJY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
TLS3_k127_3786911_4	404589.Anae109_2754	2.426e-87	305.0	COG1148@1|root,COG1148@2|Bacteria,1PTJ7@1224|Proteobacteria,42NJN@68525|delta/epsilon subdivisions,2WJHG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
TLS3_k127_3786911_7	404589.Anae109_1826	8.908e-70	252.0	COG0484@1|root,COG0484@2|Bacteria,1QYGD@1224|Proteobacteria,43CCI@68525|delta/epsilon subdivisions,2X7NG@28221|Deltaproteobacteria,2Z1CZ@29|Myxococcales	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	GSu_C4xC__C2xCH
TLS3_k127_3786911_8	290397.Adeh_2105	5.576e-58	208.0	2E533@1|root,32WWG@2|Bacteria,1QAP2@1224|Proteobacteria,4357C@68525|delta/epsilon subdivisions,2WZIC@28221|Deltaproteobacteria,2Z27M@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3786911_10	290397.Adeh_2104	1.087e-23	105.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
TLS3_k127_3786911_11	589865.DaAHT2_0380	2.5e-05	48.0	COG1373@1|root,COG1373@2|Bacteria,1R7UA@1224|Proteobacteria,42QMY@68525|delta/epsilon subdivisions,2WK60@28221|Deltaproteobacteria,2MQ2J@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
TLS3_k127_3787725_0	1254432.SCE1572_13130	1.082e-185	603.0	COG1215@1|root,COG1215@2|Bacteria,1P7GR@1224|Proteobacteria	1224|Proteobacteria	M	Bacteriophage N4 adsorption protein B	-	-	-	ko:K11740	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3
TLS3_k127_3787725_2	404589.Anae109_1327	3.854e-38	145.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2WJE3@28221|Deltaproteobacteria,2YTVE@29|Myxococcales	28221|Deltaproteobacteria	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
TLS3_k127_3790328_9	290397.Adeh_2553	9.561e-08	53.0	COG1716@1|root,COG1716@2|Bacteria,1Q2GC@1224|Proteobacteria,4382T@68525|delta/epsilon subdivisions,2X0C6@28221|Deltaproteobacteria,2YVG7@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
TLS3_k127_3790328_7	290397.Adeh_2554	1.399e-62	217.0	COG1734@1|root,COG1734@2|Bacteria,1N8RB@1224|Proteobacteria,42W5H@68525|delta/epsilon subdivisions,2WSAD@28221|Deltaproteobacteria,2YVJ6@29|Myxococcales	28221|Deltaproteobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
TLS3_k127_3790328_3	404589.Anae109_1308	2.129e-133	435.0	COG1624@1|root,COG1624@2|Bacteria,1N12B@1224|Proteobacteria,42UVR@68525|delta/epsilon subdivisions,2WQ2R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Diadenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N
TLS3_k127_3790328_2	404589.Anae109_1307	6.322e-134	453.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,42QEZ@68525|delta/epsilon subdivisions,2WKYB@28221|Deltaproteobacteria,2YZA0@29|Myxococcales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_3790328_4	404589.Anae109_1306	7.072e-123	403.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2WPRX@28221|Deltaproteobacteria,2YW8E@29|Myxococcales	28221|Deltaproteobacteria	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
TLS3_k127_3790328_6	290397.Adeh_2558	1.887e-74	255.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42R2A@68525|delta/epsilon subdivisions,2WMUK@28221|Deltaproteobacteria,2YVHG@29|Myxococcales	28221|Deltaproteobacteria	H	May be involved in the biosynthesis of molybdopterin	moaB	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
TLS3_k127_3790328_1	290397.Adeh_2560	8.852e-243	763.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2WKUP@28221|Deltaproteobacteria,2YXCT@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase beta thumb	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
TLS3_k127_3790328_0	290397.Adeh_2561	1.771e-243	761.0	COG2211@1|root,COG2211@2|Bacteria,1QTSE@1224|Proteobacteria,43C8U@68525|delta/epsilon subdivisions,2X7J6@28221|Deltaproteobacteria,2Z3H1@29|Myxococcales	28221|Deltaproteobacteria	G	Acetyl-coenzyme A transporter 1	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
TLS3_k127_3790328_5	404589.Anae109_1296	6.446e-117	384.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42T2H@68525|delta/epsilon subdivisions,2WRSP@28221|Deltaproteobacteria,2Z31G@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
TLS3_k127_3790328_8	290397.Adeh_2565	3.279e-45	168.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria,2YUQD@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
TLS3_k127_3827119_1	404589.Anae109_4169	2.861e-144	462.0	COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,42PQE@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
TLS3_k127_3827119_4	290397.Adeh_0400	7.274e-113	371.0	COG3694@1|root,COG3694@2|Bacteria,1NAPK@1224|Proteobacteria,42X7R@68525|delta/epsilon subdivisions,2WSZA@28221|Deltaproteobacteria,2YVA3@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
TLS3_k127_3827119_3	290397.Adeh_0399	3.362e-119	387.0	COG4587@1|root,COG4587@2|Bacteria,1NBY6@1224|Proteobacteria,42XYD@68525|delta/epsilon subdivisions,2WY0V@28221|Deltaproteobacteria,2YVAD@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
TLS3_k127_3827119_2	404589.Anae109_1771	2.2e-119	417.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PDY@68525|delta/epsilon subdivisions,2WUVK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
TLS3_k127_3827119_0	290397.Adeh_0396	1.018e-146	475.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,2YTWZ@29|Myxococcales	28221|Deltaproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
TLS3_k127_3827119_5	290397.Adeh_0390	8.59e-14	74.0	COG0644@1|root,COG0644@2|Bacteria,1N3JT@1224|Proteobacteria,42S0W@68525|delta/epsilon subdivisions,2WVDD@28221|Deltaproteobacteria,2YU0R@29|Myxococcales	28221|Deltaproteobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
TLS3_k127_3831978_3	404589.Anae109_2481	3.409e-61	213.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pulE-3	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
TLS3_k127_3831978_2	404589.Anae109_2485	5.625e-97	321.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,42MQB@68525|delta/epsilon subdivisions,2WPIA@28221|Deltaproteobacteria,2Z34C@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
TLS3_k127_3831978_1	404589.Anae109_2486	8.968e-147	475.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,2YWX3@29|Myxococcales	28221|Deltaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
TLS3_k127_3831978_0	404589.Anae109_2488	0.0	1053.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria,2YUHH@29|Myxococcales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
TLS3_k127_3865607_0	404589.Anae109_1873	0.0	1159.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,42M20@68525|delta/epsilon subdivisions,2WJ2N@28221|Deltaproteobacteria,2YWDH@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
TLS3_k127_3865607_2	404589.Anae109_0019	2.148e-152	497.0	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,42TD5@68525|delta/epsilon subdivisions,2WP3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	DUF5011,HYR,OMP_b-brl,OmpA,TSP_3
TLS3_k127_3865607_4	290397.Adeh_1983	1.917e-62	220.0	COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,42TIF@68525|delta/epsilon subdivisions,2WQC4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA-2	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
TLS3_k127_3865607_3	404589.Anae109_1866	6.708e-95	323.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,42QST@68525|delta/epsilon subdivisions,2WMN8@28221|Deltaproteobacteria,2YZ74@29|Myxococcales	28221|Deltaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
TLS3_k127_3865607_5	290397.Adeh_1985	4.144e-50	181.0	COG0346@1|root,COG0346@2|Bacteria,1PY3J@1224|Proteobacteria,4352G@68525|delta/epsilon subdivisions,2WZDE@28221|Deltaproteobacteria,2Z1W6@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_3865607_1	404589.Anae109_1853	0.0	1056.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria,2YU94@29|Myxococcales	28221|Deltaproteobacteria	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
TLS3_k127_3869741_2	404589.Anae109_0881	1.086e-83	299.0	COG0642@1|root,COG2205@2|Bacteria,1N9SU@1224|Proteobacteria,42ST5@68525|delta/epsilon subdivisions,2WPNG@28221|Deltaproteobacteria,2Z2WM@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_3869741_1	404589.Anae109_0880	5.643e-110	360.0	COG0745@1|root,COG0745@2|Bacteria,1Q2S0@1224|Proteobacteria,42S32@68525|delta/epsilon subdivisions,2X5XE@28221|Deltaproteobacteria,2YTZ6@29|Myxococcales	28221|Deltaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_3869741_3	290397.Adeh_2913	1.033e-18	96.0	COG3678@1|root,COG3678@2|Bacteria	2|Bacteria	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
TLS3_k127_3869741_0	290397.Adeh_0830	1.775e-242	760.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2YTUY@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter C-terminal domain	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
TLS3_k127_3894273_3	290397.Adeh_1548	1.624e-86	302.0	COG3115@1|root,COG3115@2|Bacteria,1QW35@1224|Proteobacteria,42UFZ@68525|delta/epsilon subdivisions,2WR5D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3894273_0	290397.Adeh_1547	5.318e-258	803.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	-	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
TLS3_k127_3894273_2	290397.Adeh_1544	4.747e-94	323.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WWTI@28221|Deltaproteobacteria,2Z314@29|Myxococcales	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	-	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
TLS3_k127_3894273_1	290397.Adeh_1542	6.655e-123	409.0	COG1606@1|root,COG1606@2|Bacteria,1R7UZ@1224|Proteobacteria,42Q6V@68525|delta/epsilon subdivisions,2WKIM@28221|Deltaproteobacteria,2Z04R@29|Myxococcales	28221|Deltaproteobacteria	S	Asparagine synthase	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase,QueC
TLS3_k127_3894273_5	404589.Anae109_2272	2.422e-67	239.0	COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,42ZXZ@68525|delta/epsilon subdivisions,2WVI7@28221|Deltaproteobacteria,2YV2C@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	1.8.4.10,1.8.4.8,2.7.1.25	ko:K00390,ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R02021,R04928	RC00002,RC00007,RC00078,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
TLS3_k127_38992_0	404589.Anae109_3002	9.332e-219	702.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42PZH@68525|delta/epsilon subdivisions,2WJ0T@28221|Deltaproteobacteria,2YTTX@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
TLS3_k127_38992_1	1242864.D187_002166	1.684e-114	400.0	COG3021@1|root,COG3021@2|Bacteria,1QX6S@1224|Proteobacteria,43BZH@68525|delta/epsilon subdivisions,2X7A9@28221|Deltaproteobacteria,2Z3EK@29|Myxococcales	28221|Deltaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_3900986_5	404589.Anae109_4415	7.044e-62	220.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42NUE@68525|delta/epsilon subdivisions,2WMSB@28221|Deltaproteobacteria,2Z33U@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
TLS3_k127_3900986_1	404589.Anae109_4416	4.664e-177	562.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2WKHJ@28221|Deltaproteobacteria,2YW9B@29|Myxococcales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
TLS3_k127_3900986_2	290397.Adeh_4264	2.868e-159	512.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,42N8K@68525|delta/epsilon subdivisions,2WK5Q@28221|Deltaproteobacteria,2Z31B@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
TLS3_k127_3900986_0	290397.Adeh_4265	4.072e-227	738.0	COG2304@1|root,COG2304@2|Bacteria,1NX8F@1224|Proteobacteria,430QD@68525|delta/epsilon subdivisions,2WVNR@28221|Deltaproteobacteria,2YW4W@29|Myxococcales	28221|Deltaproteobacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
TLS3_k127_3900986_3	404589.Anae109_4421	5.178e-113	383.0	COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,43B77@68525|delta/epsilon subdivisions,2X6KN@28221|Deltaproteobacteria,2Z3BN@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TLS3_k127_3900986_4	404589.Anae109_4422	1.551e-108	354.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YWPA@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase associated with various cellular activities	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TLS3_k127_3917261_0	404589.Anae109_0730	2.66e-295	927.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2YUDZ@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
TLS3_k127_3917261_1	290397.Adeh_0685	5.66e-288	893.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2YUKY@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
TLS3_k127_3917261_2	290397.Adeh_0684	6.953e-186	588.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
TLS3_k127_3917261_6	404589.Anae109_0727	1.074e-48	177.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
TLS3_k127_3917261_5	404589.Anae109_0726	2.747e-51	195.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	gspH	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02456,ko:K02457,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	GspH,N_methyl
TLS3_k127_3917261_7	404589.Anae109_0725	1.659e-47	185.0	COG4967@1|root,COG4967@2|Bacteria,1QUS3@1224|Proteobacteria,42X07@68525|delta/epsilon subdivisions,2WSQI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	gspI	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
TLS3_k127_3917261_9	215803.DB30_5341	2.973e-37	161.0	COG4968@1|root,COG4968@2|Bacteria,1QX7U@1224|Proteobacteria,43C0U@68525|delta/epsilon subdivisions,2X7BG@28221|Deltaproteobacteria,2Z3F1@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein J	-	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
TLS3_k127_3917261_4	290397.Adeh_0679	2.723e-81	296.0	COG3156@1|root,COG3156@2|Bacteria,1RIW9@1224|Proteobacteria,42V6H@68525|delta/epsilon subdivisions,2X2BW@28221|Deltaproteobacteria,2YVV7@29|Myxococcales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
TLS3_k127_3917261_3	404589.Anae109_0722	5.004e-148	504.0	COG4972@1|root,COG4972@2|Bacteria,1MYIB@1224|Proteobacteria,42SIX@68525|delta/epsilon subdivisions,2WP1G@28221|Deltaproteobacteria,2YVKD@29|Myxococcales	28221|Deltaproteobacteria	NU	Type IV pilus assembly protein PilM;	gspL	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,PilM_2,PilN,T2SSL
TLS3_k127_3917261_8	404589.Anae109_0721	3.605e-45	184.0	COG3149@1|root,COG3149@2|Bacteria,1NEZ3@1224|Proteobacteria,42WMP@68525|delta/epsilon subdivisions,2WSE1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein M	-	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
TLS3_k127_3917261_10	404589.Anae109_0720	7.485e-25	116.0	2DRH1@1|root,33BQ8@2|Bacteria,1NM8D@1224|Proteobacteria,42XND@68525|delta/epsilon subdivisions,2WSKN@28221|Deltaproteobacteria,2YW71@29|Myxococcales	28221|Deltaproteobacteria	-	-	gspN	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
TLS3_k127_4021790_2	404589.Anae109_2968	2.738e-188	591.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,42P6Z@68525|delta/epsilon subdivisions,2WK5W@28221|Deltaproteobacteria,2YUMK@29|Myxococcales	28221|Deltaproteobacteria	G	Maltogenic Amylase, C-terminal domain	treS	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
TLS3_k127_4021790_1	404589.Anae109_2966	7.737e-210	663.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,42PZB@68525|delta/epsilon subdivisions,2WK77@28221|Deltaproteobacteria,2YVA7@29|Myxococcales	28221|Deltaproteobacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
TLS3_k127_4021790_9	404589.Anae109_2965	1.762e-47	192.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,42XYJ@68525|delta/epsilon subdivisions,2WSKT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Conserved TM helix repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
TLS3_k127_4021790_5	404589.Anae109_2964	5.237e-74	266.0	COG0463@1|root,COG0463@2|Bacteria,1R547@1224|Proteobacteria,42PDC@68525|delta/epsilon subdivisions,2WKYW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	glycosyl transferase family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
TLS3_k127_4021790_0	404380.Gbem_1958	1.116e-226	747.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,42MPB@68525|delta/epsilon subdivisions,2WJUV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_4021790_7	290397.Adeh_3745	1.342e-60	238.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
TLS3_k127_4021790_11	404589.Anae109_3861	7.841e-22	101.0	COG4770@1|root,COG4770@2|Bacteria,1NJ80@1224|Proteobacteria	1224|Proteobacteria	I	Acetyl propionyl-CoA carboxylase alpha subunit	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
TLS3_k127_4021790_4	404589.Anae109_3860	1.888e-98	330.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,43AM0@68525|delta/epsilon subdivisions,2X615@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.1.1.41	ko:K11264	ko00640,map00640	-	R00923	RC00097	ko00000,ko00001,ko01000	-	-	-	ECH_1
TLS3_k127_4021790_3	404589.Anae109_3858	5.202e-162	520.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TLS3_k127_4021790_8	290397.Adeh_3733	3.106e-59	225.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,42SUR@68525|delta/epsilon subdivisions,2WPNH@28221|Deltaproteobacteria,2Z2JJ@29|Myxococcales	28221|Deltaproteobacteria	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
TLS3_k127_4021790_6	290397.Adeh_3732	7.067e-61	225.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,43CCW@68525|delta/epsilon subdivisions,2X7NT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_6
TLS3_k127_4021790_10	378806.STAUR_2805	1.199e-31	127.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,42Q8W@68525|delta/epsilon subdivisions,2WJVN@28221|Deltaproteobacteria,2YY2E@29|Myxococcales	28221|Deltaproteobacteria	EU	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
TLS3_k127_4024249_6	1382303.JPOM01000001_gene1205	1.92e-30	120.0	COG1262@1|root,COG4301@1|root,COG1262@2|Bacteria,COG4301@2|Bacteria,1MUNC@1224|Proteobacteria,2TQXE@28211|Alphaproteobacteria,2KFXT@204458|Caulobacterales	204458|Caulobacterales	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_33
TLS3_k127_4024249_3	404589.Anae109_2422	9.93e-100	338.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,42SR8@68525|delta/epsilon subdivisions,2WPN0@28221|Deltaproteobacteria,2YYWZ@29|Myxococcales	28221|Deltaproteobacteria	S	Histidine-specific methyltransferase, SAM-dependent	-	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
TLS3_k127_4024249_0	404589.Anae109_2417	5e-324	1012.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2WJ2C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase M1 membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,ERAP1_C,Peptidase_M1
TLS3_k127_4024249_4	227882.SAV_3244	3.475e-70	260.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria	201174|Actinobacteria	H	bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
TLS3_k127_4024249_2	404589.Anae109_2416	3.232e-139	454.0	COG2211@1|root,COG2211@2|Bacteria,1N1ER@1224|Proteobacteria	1224|Proteobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
TLS3_k127_4024249_1	290397.Adeh_1421	1.581e-232	733.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42PJQ@68525|delta/epsilon subdivisions,2WKR4@28221|Deltaproteobacteria,2YYSC@29|Myxococcales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
TLS3_k127_4024249_5	404589.Anae109_4443	1.441e-39	148.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,42MFN@68525|delta/epsilon subdivisions,2WIJE@28221|Deltaproteobacteria,2YXG7@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
TLS3_k127_4024249_7	871963.Desdi_1485	1.185e-10	69.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,26192@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02615	GDP_Man_Dehyd
TLS3_k127_4025115_7	404589.Anae109_2843	1.481e-100	343.0	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria	1224|Proteobacteria	Q	Acyltransferase, ws dgat mgat	-	-	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
TLS3_k127_4025115_8	290397.Adeh_2981	6.762e-96	328.0	COG3016@1|root,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,42U2R@68525|delta/epsilon subdivisions,2WM9S@28221|Deltaproteobacteria,2YZVS@29|Myxococcales	28221|Deltaproteobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2
TLS3_k127_4025115_3	404589.Anae109_2924	6.507e-205	648.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,42NEN@68525|delta/epsilon subdivisions,2WKJP@28221|Deltaproteobacteria,2Z1DV@29|Myxococcales	28221|Deltaproteobacteria	C	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
TLS3_k127_4025115_10	404589.Anae109_2923	2.881e-91	304.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,42RQB@68525|delta/epsilon subdivisions,2WNZN@28221|Deltaproteobacteria,2Z2K9@29|Myxococcales	28221|Deltaproteobacteria	Q	PFAM Tripartite ATP-independent periplasmic transporter DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
TLS3_k127_4025115_0	404589.Anae109_2922	4.699e-266	865.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,42YBQ@68525|delta/epsilon subdivisions,2WTKK@28221|Deltaproteobacteria,2Z06Q@29|Myxococcales	28221|Deltaproteobacteria	Q	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
TLS3_k127_4025115_1	290397.Adeh_2867	7.364e-264	821.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42YJQ@68525|delta/epsilon subdivisions,2WTJP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
TLS3_k127_4025115_5	290397.Adeh_2866	1.146e-135	465.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria	1224|Proteobacteria	C	PFAM FAD linked oxidase domain protein	glcE	GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616	1.1.3.15	ko:K00104,ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	iETEC_1333.ETEC_3246	FAD-oxidase_C,FAD_binding_4
TLS3_k127_4025115_2	404589.Anae109_2919	1.091e-207	655.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42MMF@68525|delta/epsilon subdivisions,2WJ1F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
TLS3_k127_4025115_16	1304880.JAGB01000002_gene1925	1.213e-29	126.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24E6I@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
TLS3_k127_4025115_9	1304865.JAGF01000001_gene1501	2.106e-92	316.0	COG1335@1|root,COG1335@2|Bacteria,2I9AW@201174|Actinobacteria	201174|Actinobacteria	Q	isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
TLS3_k127_4025115_4	706587.Desti_5367	5.853e-152	490.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
TLS3_k127_4025115_15	706587.Desti_5368	2.937e-60	238.0	COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,42RPK@68525|delta/epsilon subdivisions,2WNSW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Amino acid amide ABC transporter ATP-binding protein 1, HAAT family	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
TLS3_k127_4025115_14	706587.Desti_5369	1.326e-64	241.0	COG0410@1|root,COG0410@2|Bacteria,1MY03@1224|Proteobacteria	1224|Proteobacteria	E	ATPases associated with a variety of cellular activities	MA20_39795	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
TLS3_k127_4025115_12	706587.Desti_5370	8.537e-89	304.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,42T4B@68525|delta/epsilon subdivisions,2WPI9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
TLS3_k127_4025115_11	706587.Desti_5371	6.12e-89	315.0	COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,43AR4@68525|delta/epsilon subdivisions,2X652@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
TLS3_k127_4025115_6	1125863.JAFN01000001_gene983	3.074e-126	417.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,42Q1H@68525|delta/epsilon subdivisions,2WK7W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM MOFRL domain protein	Glyctk	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
TLS3_k127_4025115_13	290397.Adeh_1858	2.988e-83	280.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42P72@68525|delta/epsilon subdivisions,2WKRS@28221|Deltaproteobacteria,2YXDE@29|Myxococcales	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	gyaR	-	1.1.1.26	ko:K00015,ko:K15893	ko00260,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map01100,map01110,map01120,map01130,map01200	M00532	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TLS3_k127_4025599_2	404589.Anae109_0226	1.096e-76	262.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2WIVS@28221|Deltaproteobacteria,2YTY2@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3198	AA_kinase,PUA
TLS3_k127_4025599_3	1461579.CCNK01000036_gene1588	6.299e-27	121.0	COG1442@1|root,COG1442@2|Bacteria,1RGSD@1224|Proteobacteria,1SG7T@1236|Gammaproteobacteria,1Y7GK@135625|Pasteurellales	135625|Pasteurellales	M	glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4025599_0	404589.Anae109_0218	1.187e-286	890.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42NA6@68525|delta/epsilon subdivisions,2WIMU@28221|Deltaproteobacteria,2YU9T@29|Myxococcales	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
TLS3_k127_4025599_1	290397.Adeh_0243	1.359e-218	685.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2WWD4@28221|Deltaproteobacteria,2YTYG@29|Myxococcales	28221|Deltaproteobacteria	S	oligopeptide transporter, OPT family	-	-	-	-	-	-	-	-	-	-	-	-	OPT
TLS3_k127_4036136_5	1278073.MYSTI_03119	4.835e-05	51.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,42U06@68525|delta/epsilon subdivisions,2WQXU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_4036136_1	243231.GSU1016	1.302e-214	683.0	COG0569@1|root,COG2985@1|root,COG0569@2|Bacteria,COG2985@2|Bacteria,1MUVM@1224|Proteobacteria,42P36@68525|delta/epsilon subdivisions,2WKGD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM YidE YbjL duplication	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
TLS3_k127_4036136_0	404589.Anae109_3440	4.418e-302	939.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2YUNQ@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	rep	-	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
TLS3_k127_4036136_3	290397.Adeh_3372	7.437e-68	237.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2WP5M@28221|Deltaproteobacteria,2YVJG@29|Myxococcales	28221|Deltaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
TLS3_k127_4036136_4	404589.Anae109_3436	5.87e-65	224.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,42SVI@68525|delta/epsilon subdivisions,2WP7T@28221|Deltaproteobacteria,2YV9P@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
TLS3_k127_4036136_2	290397.Adeh_3368	7.448e-123	398.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
TLS3_k127_4045622_3	1487953.JMKF01000035_gene1205	2.537e-31	135.0	2DBB1@1|root,2Z854@2|Bacteria,1G05N@1117|Cyanobacteria,1H7Z3@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
TLS3_k127_4045622_0	404589.Anae109_3354	2.814e-132	444.0	COG4585@1|root,COG4585@2|Bacteria,1RBN9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
TLS3_k127_4045622_2	404589.Anae109_3355	3.521e-57	225.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria	1224|Proteobacteria	K	response regulator	-	-	-	ko:K07685	ko02020,map02020	M00472	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
TLS3_k127_4045622_4	469371.Tbis_1507	5.581e-24	109.0	2ACKQ@1|root,31274@2|Bacteria,2HSCP@201174|Actinobacteria,4ED9Q@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4045622_1	404589.Anae109_1739	8.578e-79	268.0	COG3148@1|root,COG3148@2|Bacteria,1MZCN@1224|Proteobacteria,42S7K@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Dtw domain containing protein	MA20_30020	-	-	ko:K05812	-	-	-	-	ko00000	-	-	-	DTW
TLS3_k127_4055778_6	404589.Anae109_0435	1.885e-31	126.0	COG0584@1|root,COG0584@2|Bacteria,1MW6Z@1224|Proteobacteria	1224|Proteobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
TLS3_k127_4055778_5	404589.Anae109_0795	2.008e-51	190.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
TLS3_k127_4055778_8	404589.Anae109_1009	4.871e-14	78.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	btrV	-	2.4.1.187,2.7.11.1	ko:K02066,ko:K02660,ko:K04749,ko:K04757,ko:K05946,ko:K06378	ko02010,ko02020,ko02025,ko05111,map02010,map02020,map02025,map05111	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01003,ko02000,ko02035,ko02044,ko03021	3.A.1.27	GT26	-	APH,STAS,STAS_2
TLS3_k127_4055778_1	404589.Anae109_3481	6.515e-148	477.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,42RUS@68525|delta/epsilon subdivisions,2WNWT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
TLS3_k127_4055778_3	404589.Anae109_0897	2.871e-104	344.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,42MWS@68525|delta/epsilon subdivisions,2WMMP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	yadG	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_4055778_2	290397.Adeh_0836	1.257e-115	386.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,42PXX@68525|delta/epsilon subdivisions,2WIMB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Transport permease protein	yadH	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
TLS3_k127_4055778_4	404589.Anae109_0899	4.229e-84	287.0	28PU4@1|root,2ZCF6@2|Bacteria,1RBK2@1224|Proteobacteria,43B3E@68525|delta/epsilon subdivisions,2X6H4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4055778_0	404589.Anae109_0900	2.149e-191	612.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria,2YX5W@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
TLS3_k127_40747_9	398525.KB900701_gene3864	0.0003881	44.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,2TSM1@28211|Alphaproteobacteria,3JUKA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
TLS3_k127_40747_1	404589.Anae109_2848	2.786e-111	366.0	COG0583@1|root,COG0583@2|Bacteria,1NUAB@1224|Proteobacteria,42RIV@68525|delta/epsilon subdivisions,2WNHX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS3_k127_40747_2	404589.Anae109_1756	2.178e-104	349.0	COG0667@1|root,COG0667@2|Bacteria,1NSK8@1224|Proteobacteria	1224|Proteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_40747_3	290397.Adeh_3190	6.6e-87	291.0	COG4309@1|root,COG4309@2|Bacteria,1P367@1224|Proteobacteria,42TEV@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,DUF2249
TLS3_k127_40747_0	290397.Adeh_3191	7.217e-229	724.0	COG2461@1|root,COG2461@2|Bacteria,1R5J5@1224|Proteobacteria,42QAZ@68525|delta/epsilon subdivisions,2WQTR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain	-	-	-	ko:K09155	-	-	-	-	ko00000	-	-	-	DUF1858,DUF438,Hemerythrin,PAS_10
TLS3_k127_40747_7	290397.Adeh_0988	7.464e-32	132.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WQ3M@28221|Deltaproteobacteria,2Z1Q1@29|Myxococcales	28221|Deltaproteobacteria	K	Cold-shock protein	cspE	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
TLS3_k127_40747_4	290397.Adeh_3904	7.815e-85	293.0	2CJTZ@1|root,32SAS@2|Bacteria,1N3WB@1224|Proteobacteria,42XK5@68525|delta/epsilon subdivisions,2WSKQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3553
TLS3_k127_40747_5	290397.Adeh_0964	2.236e-58	224.0	COG1075@1|root,COG1075@2|Bacteria,1R88U@1224|Proteobacteria,4389A@68525|delta/epsilon subdivisions,2XA37@28221|Deltaproteobacteria,2YW9M@29|Myxococcales	28221|Deltaproteobacteria	S	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PGAP1
TLS3_k127_4075576_3	477974.Daud_0418	4.009e-64	233.0	COG1656@1|root,COG2104@1|root,COG1656@2|Bacteria,COG2104@2|Bacteria,1V62E@1239|Firmicutes,24IZW@186801|Clostridia	186801|Clostridia	H	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
TLS3_k127_4075576_2	1278073.MYSTI_07598	3.07e-82	304.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	asgD	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
TLS3_k127_4075576_1	290397.Adeh_2440	1.403e-183	584.0	COG0151@1|root,COG0151@2|Bacteria,1NA76@1224|Proteobacteria,43CA7@68525|delta/epsilon subdivisions,2X7KS@28221|Deltaproteobacteria,2Z204@29|Myxococcales	28221|Deltaproteobacteria	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
TLS3_k127_4075576_0	290397.Adeh_2438	1.443e-190	604.0	COG1032@1|root,COG1032@2|Bacteria,1Q3ZA@1224|Proteobacteria,439T3@68525|delta/epsilon subdivisions,2X567@28221|Deltaproteobacteria,2Z064@29|Myxococcales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TLS3_k127_408212_1	404589.Anae109_0737	1.357e-188	594.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,2YUJ4@29|Myxococcales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
TLS3_k127_408212_2	290397.Adeh_0694	2.686e-25	109.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,42V8V@68525|delta/epsilon subdivisions,2WRKG@28221|Deltaproteobacteria,2Z1JK@29|Myxococcales	28221|Deltaproteobacteria	C	acylphosphatase activity	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
TLS3_k127_408212_0	290397.Adeh_0693	0.0	1039.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria,2YU7A@29|Myxococcales	28221|Deltaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
TLS3_k127_408212_3	404589.Anae109_0680	3.122e-10	70.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
TLS3_k127_4084623_0	404589.Anae109_0189	1.284e-275	867.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2YVGM@29|Myxococcales	28221|Deltaproteobacteria	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
TLS3_k127_4084623_8	448385.sce1174	3.746e-21	109.0	COG0784@1|root,COG0784@2|Bacteria,1RDJG@1224|Proteobacteria,43CU2@68525|delta/epsilon subdivisions,2X81N@28221|Deltaproteobacteria,2Z3JA@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_4084623_4	1242864.D187_005925	2.417e-70	252.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X791@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
TLS3_k127_4084623_3	243231.GSU2567	3.928e-73	259.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HAMP,HATPase_c,HisKA,MASE3,PAS_3,PAS_4,PAS_9,dCache_1
TLS3_k127_4084623_6	290397.Adeh_4140	4.827e-33	130.0	COG3461@1|root,COG3461@2|Bacteria,1MZZN@1224|Proteobacteria,434A9@68525|delta/epsilon subdivisions,2X0BK@28221|Deltaproteobacteria,2YVPK@29|Myxococcales	28221|Deltaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K09700	-	-	-	-	ko00000	-	-	-	-
TLS3_k127_4084623_5	290397.Adeh_4148	1.516e-59	215.0	COG0558@1|root,COG0558@2|Bacteria,1N9TT@1224|Proteobacteria,42V2Q@68525|delta/epsilon subdivisions,2WRYY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
TLS3_k127_4084623_1	290397.Adeh_4149	1.609e-211	666.0	COG1260@1|root,COG1260@2|Bacteria,1N0D9@1224|Proteobacteria,42NWK@68525|delta/epsilon subdivisions,2WM2T@28221|Deltaproteobacteria,2YYFZ@29|Myxococcales	28221|Deltaproteobacteria	I	synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
TLS3_k127_4084623_2	404589.Anae109_0574	2.476e-177	570.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WN60@28221|Deltaproteobacteria,2YUZ0@29|Myxococcales	28221|Deltaproteobacteria	FP	Ppx/GppA phosphatase family	gppA-2	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
TLS3_k127_4084623_7	404589.Anae109_0571	2.934e-21	98.0	COG5607@1|root,COG5607@2|Bacteria,1NGVB@1224|Proteobacteria,42X7Z@68525|delta/epsilon subdivisions,2WSMB@28221|Deltaproteobacteria,2Z2C0@29|Myxococcales	28221|Deltaproteobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
TLS3_k127_4089352_2	290397.Adeh_1329	3.403e-127	412.0	COG0642@1|root,COG2205@2|Bacteria,1QX6V@1224|Proteobacteria,43AID@68525|delta/epsilon subdivisions,2X5YM@28221|Deltaproteobacteria,2YUUS@29|Myxococcales	28221|Deltaproteobacteria	T	Protoglobin	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Protoglobin
TLS3_k127_4089352_4	404589.Anae109_2439	2.688e-95	317.0	COG0745@1|root,COG4566@1|root,COG0745@2|Bacteria,COG4566@2|Bacteria,1QYFX@1224|Proteobacteria	1224|Proteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_4089352_1	290397.Adeh_1327	4.579e-157	514.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M6C@68525|delta/epsilon subdivisions,2WM3G@28221|Deltaproteobacteria,2YV02@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
TLS3_k127_4089352_6	404589.Anae109_3857	6.903e-44	181.0	COG3829@1|root,COG3829@2|Bacteria,1QVJM@1224|Proteobacteria,43CC9@68525|delta/epsilon subdivisions,2X7N5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4
TLS3_k127_4089352_0	215803.DB30_8405	7.828e-215	677.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTW0@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_4089352_3	404589.Anae109_2443	1.173e-98	326.0	COG2896@1|root,COG2896@2|Bacteria,1QYFW@1224|Proteobacteria,4315C@68525|delta/epsilon subdivisions,2WX3Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
TLS3_k127_4089352_8	404589.Anae109_2444	1.504e-34	135.0	COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria	1224|Proteobacteria	T	dnak suppressor protein	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
TLS3_k127_4089352_7	290397.Adeh_1321	1.275e-42	162.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_4089352_5	290397.Adeh_1317	3.221e-90	299.0	COG3170@1|root,COG3481@1|root,COG3170@2|Bacteria,COG3481@2|Bacteria,1NH0C@1224|Proteobacteria,42Q7X@68525|delta/epsilon subdivisions,2WJW2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Nucleic acid binding OB-fold tRNA helicase-type	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
TLS3_k127_4131511_2	404589.Anae109_2956	9.891e-90	301.0	COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,42R3E@68525|delta/epsilon subdivisions,2WN3C@28221|Deltaproteobacteria,2Z350@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Methyltrans_RNA
TLS3_k127_4131511_4	290397.Adeh_3844	7.38e-27	114.0	COG0745@1|root,COG0745@2|Bacteria,1NBDV@1224|Proteobacteria,42UVC@68525|delta/epsilon subdivisions,2WQ45@28221|Deltaproteobacteria,2Z0Z9@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_4131511_3	35754.JNYJ01000035_gene3839	9.647e-78	269.0	COG4249@1|root,COG4249@2|Bacteria,2IB3R@201174|Actinobacteria,4DIC8@85008|Micromonosporales	201174|Actinobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Peptidase_C14
TLS3_k127_4131511_0	290397.Adeh_2039	3.216e-208	663.0	COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,42ZD0@68525|delta/epsilon subdivisions,2WU4P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation	aceK	-	2.7.11.5	ko:K00906	-	-	-	-	ko00000,ko01000	-	-	-	AceK
TLS3_k127_4131511_1	404589.Anae109_0056	7.295e-123	400.0	COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,42M4U@68525|delta/epsilon subdivisions,2WJJI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	PFAM Xanthine uracil vitamin C permease	uraA	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
TLS3_k127_418397_17	404589.Anae109_1795	1.24e-15	76.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,42MPM@68525|delta/epsilon subdivisions,2WKPX@28221|Deltaproteobacteria,2YURJ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
TLS3_k127_418397_2	404589.Anae109_2991	2.498e-200	642.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH,HNH_4
TLS3_k127_418397_12	404589.Anae109_3517	2.078e-44	162.0	2CZ4M@1|root,32T5I@2|Bacteria,1N344@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_418397_9	443143.GM18_4332	9.462e-49	190.0	COG2050@1|root,COG2050@2|Bacteria,1PP3U@1224|Proteobacteria,43E7M@68525|delta/epsilon subdivisions,2X2FF@28221|Deltaproteobacteria,43V5X@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Thioesterase-like superfamily	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
TLS3_k127_418397_7	1227497.C491_20342	6.576e-65	235.0	COG0508@1|root,arCOG01706@2157|Archaea,2XUGY@28890|Euryarchaeota,23V33@183963|Halobacteria	183963|Halobacteria	C	COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh
TLS3_k127_418397_6	404589.Anae109_0032	5.239e-94	322.0	COG0300@1|root,COG0300@2|Bacteria,1RGKZ@1224|Proteobacteria,43BQ7@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	ybbO	GO:0003674,GO:0003824,GO:0004033,GO:0008106,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
TLS3_k127_418397_8	1144275.COCOR_07994	1.402e-56	212.0	COG0204@1|root,COG0204@2|Bacteria,1RB47@1224|Proteobacteria,43103@68525|delta/epsilon subdivisions,2WX42@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DAGAT
TLS3_k127_418397_11	1144275.COCOR_07995	2.077e-46	181.0	COG1073@1|root,COG1073@2|Bacteria,1R0IM@1224|Proteobacteria,43CXK@68525|delta/epsilon subdivisions,2X85P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_418397_13	378806.STAUR_6242	2.729e-42	173.0	COG3145@1|root,COG3145@2|Bacteria,1RDBK@1224|Proteobacteria	1224|Proteobacteria	L	Pfam 2OG-Fe(II) oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
TLS3_k127_418397_4	404589.Anae109_1793	9.109e-121	404.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,42PJP@68525|delta/epsilon subdivisions,2WJI0@28221|Deltaproteobacteria,2YXVU@29|Myxococcales	28221|Deltaproteobacteria	P	Membrane protein, TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
TLS3_k127_418397_3	404589.Anae109_1792	5.327e-132	426.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,42UN5@68525|delta/epsilon subdivisions,2WQU9@28221|Deltaproteobacteria,2YXHW@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
TLS3_k127_418397_14	404589.Anae109_1790	4.897e-36	138.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,42Y0E@68525|delta/epsilon subdivisions,2WT2T@28221|Deltaproteobacteria,2YVTQ@29|Myxococcales	28221|Deltaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
TLS3_k127_418397_15	1144275.COCOR_00751	1.805e-33	136.0	2DS0Y@1|root,32US3@2|Bacteria,1Q9M4@1224|Proteobacteria,434GI@68525|delta/epsilon subdivisions,2X8VU@28221|Deltaproteobacteria,2Z0KU@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_418397_10	1278073.MYSTI_00509	4.328e-48	176.0	COG0537@1|root,COG0537@2|Bacteria,1NMG6@1224|Proteobacteria,433UI@68525|delta/epsilon subdivisions,2X3IV@28221|Deltaproteobacteria,2YZYP@29|Myxococcales	28221|Deltaproteobacteria	FG	adenosine 5'-monophosphoramidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_418397_0	1242864.D187_007734	2.319e-266	833.0	COG1164@1|root,COG1164@2|Bacteria,1MWYN@1224|Proteobacteria,437WG@68525|delta/epsilon subdivisions,2X364@28221|Deltaproteobacteria,2YUG4@29|Myxococcales	28221|Deltaproteobacteria	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
TLS3_k127_418397_1	404589.Anae109_1722	1.994e-230	749.0	COG0642@1|root,COG3614@1|root,COG2205@2|Bacteria,COG3614@2|Bacteria,1NRP8@1224|Proteobacteria,42RDI@68525|delta/epsilon subdivisions,2WU70@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,HATPase_c,HisKA
TLS3_k127_418397_5	290397.Adeh_2027	2.955e-94	316.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria	1224|Proteobacteria	GM	Nad-dependent epimerase dehydratase	yeeZ	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind
TLS3_k127_4249536_6	1158318.ATXC01000001_gene948	1.529e-06	50.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_2,TonB_C
TLS3_k127_4249536_3	404589.Anae109_4218	1.547e-99	329.0	COG2041@1|root,COG2041@2|Bacteria,1MWZK@1224|Proteobacteria,42W6K@68525|delta/epsilon subdivisions,2WS34@28221|Deltaproteobacteria,2YZXI@29|Myxococcales	28221|Deltaproteobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
TLS3_k127_4249536_5	404589.Anae109_4217	3.545e-56	199.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
TLS3_k127_4249536_2	404589.Anae109_4216	6.066e-100	351.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,42N9N@68525|delta/epsilon subdivisions,2WNAZ@28221|Deltaproteobacteria,2Z2YU@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
TLS3_k127_4249536_0	404589.Anae109_4215	2.555e-213	668.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2WJ7W@28221|Deltaproteobacteria,2YUNU@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
TLS3_k127_4249536_4	290397.Adeh_2883	4.166e-78	267.0	COG0500@1|root,COG2226@2|Bacteria,1N5DK@1224|Proteobacteria,43CKW@68525|delta/epsilon subdivisions,2X610@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_4249536_1	290397.Adeh_2882	1.397e-143	466.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,1NIJG@1224|Proteobacteria	1224|Proteobacteria	IT	DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
TLS3_k127_4277715_9	1385517.N800_02520	8.15e-16	78.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1X4UN@135614|Xanthomonadales	135614|Xanthomonadales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
TLS3_k127_4277715_2	1242864.D187_003305	4.497e-257	804.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria	1224|Proteobacteria	EG	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
TLS3_k127_4277715_1	290397.Adeh_1978	6.662e-295	913.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria,2YXEU@29|Myxococcales	28221|Deltaproteobacteria	H	acetolactate synthase	-	-	2.2.1.6,4.1.1.7	ko:K01576,ko:K01652	ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00595,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TLS3_k127_4277715_6	290397.Adeh_1977	1.625e-79	269.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,42RRU@68525|delta/epsilon subdivisions,2WNBY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	TIGRFAM Acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
TLS3_k127_4277715_3	404589.Anae109_1879	1.488e-190	602.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2WJW8@28221|Deltaproteobacteria,2YU99@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
TLS3_k127_4277715_5	290397.Adeh_1975	1.452e-97	324.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,42RHA@68525|delta/epsilon subdivisions,2WNQW@28221|Deltaproteobacteria,2YVAJ@29|Myxococcales	28221|Deltaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
TLS3_k127_4277715_8	404589.Anae109_1881	4.192e-31	127.0	COG0291@1|root,COG0291@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
TLS3_k127_4277715_7	404589.Anae109_1882	1.958e-53	191.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,42REF@68525|delta/epsilon subdivisions,2WQ4F@28221|Deltaproteobacteria,2YVYH@29|Myxococcales	28221|Deltaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
TLS3_k127_4277715_4	404589.Anae109_1883	1.072e-187	593.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2WJ42@28221|Deltaproteobacteria,2YWE0@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415	Phe_tRNA-synt_N,tRNA-synt_2d
TLS3_k127_4277715_0	404589.Anae109_1884	0.0	1054.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2YYU4@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
TLS3_k127_4316761_1	404589.Anae109_2321	4.562e-109	362.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42RAB@68525|delta/epsilon subdivisions,2X5MA@28221|Deltaproteobacteria,2Z369@29|Myxococcales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
TLS3_k127_4316761_2	1123320.KB889562_gene6664	1.21e-16	84.0	COG2197@1|root,COG2197@2|Bacteria,2IKVZ@201174|Actinobacteria	201174|Actinobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_4316761_0	404589.Anae109_2834	1.462e-226	706.0	COG3214@1|root,COG3214@2|Bacteria,1N40B@1224|Proteobacteria,437I2@68525|delta/epsilon subdivisions,2X2RH@28221|Deltaproteobacteria,2YVNV@29|Myxococcales	28221|Deltaproteobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
TLS3_k127_4348834_2	404589.Anae109_0924	1.438e-81	276.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,42R4C@68525|delta/epsilon subdivisions,2WKG9@28221|Deltaproteobacteria,2Z24Q@29|Myxococcales	28221|Deltaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
TLS3_k127_4348834_3	1254432.SCE1572_16225	1.377e-26	115.0	COG3695@1|root,COG3695@2|Bacteria,1PZ1K@1224|Proteobacteria,42WV5@68525|delta/epsilon subdivisions,2WT08@28221|Deltaproteobacteria,2YVVE@29|Myxococcales	28221|Deltaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
TLS3_k127_4348834_0	404589.Anae109_0921	0.0	1362.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42N22@68525|delta/epsilon subdivisions,2WIMH@28221|Deltaproteobacteria,2YUIS@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
TLS3_k127_4348834_1	290397.Adeh_0863	9.016e-219	686.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,42N09@68525|delta/epsilon subdivisions,2WIRX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_4356568_11	404589.Anae109_2649	6.14e-13	72.0	COG4974@1|root,COG4974@2|Bacteria,1QUFQ@1224|Proteobacteria,43CG3@68525|delta/epsilon subdivisions,2X7R3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
TLS3_k127_4356568_9	404589.Anae109_2649	2.442e-26	113.0	COG4974@1|root,COG4974@2|Bacteria,1QUFQ@1224|Proteobacteria,43CG3@68525|delta/epsilon subdivisions,2X7R3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
TLS3_k127_4356568_0	404589.Anae109_2667	5.782e-161	514.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,42P5X@68525|delta/epsilon subdivisions,2WIQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
TLS3_k127_4356568_4	404589.Anae109_2668	6.214e-73	251.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,42UCT@68525|delta/epsilon subdivisions,2WPAW@28221|Deltaproteobacteria,2YV7B@29|Myxococcales	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
TLS3_k127_4356568_6	1144275.COCOR_02451	9.607e-62	237.0	COG1524@1|root,COG1524@2|Bacteria,1QX9K@1224|Proteobacteria	1224|Proteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
TLS3_k127_4356568_2	404589.Anae109_2670	4.784e-87	298.0	COG3568@1|root,COG3568@2|Bacteria,1R977@1224|Proteobacteria,43AKV@68525|delta/epsilon subdivisions,2X60Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_4356568_3	404589.Anae109_2672	1.068e-80	276.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,42RJR@68525|delta/epsilon subdivisions,2WMK3@28221|Deltaproteobacteria,2YVG8@29|Myxococcales	28221|Deltaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
TLS3_k127_4356568_5	290397.Adeh_2684	3.197e-65	238.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2WPDF@28221|Deltaproteobacteria,2YVGY@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
TLS3_k127_4356568_1	404589.Anae109_2676	1.97e-135	440.0	COG3320@1|root,COG3320@2|Bacteria,1QSHC@1224|Proteobacteria,42W94@68525|delta/epsilon subdivisions,2WR9E@28221|Deltaproteobacteria,2YUNG@29|Myxococcales	28221|Deltaproteobacteria	Q	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
TLS3_k127_4356568_7	404589.Anae109_2677	7.861e-42	171.0	COG2030@1|root,COG2030@2|Bacteria,1QXU8@1224|Proteobacteria,43C6S@68525|delta/epsilon subdivisions,2X7GZ@28221|Deltaproteobacteria,2YW6B@29|Myxococcales	28221|Deltaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
TLS3_k127_4388465_3	290397.Adeh_1496	1.423e-88	323.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria,2YVIZ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
TLS3_k127_4388465_0	290397.Adeh_1495	0.0	1069.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2YUHW@29|Myxococcales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
TLS3_k127_4388465_2	404589.Anae109_2339	1.026e-89	308.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,2YVDX@29|Myxococcales	28221|Deltaproteobacteria	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
TLS3_k127_4388465_1	290397.Adeh_1491	3.122e-150	481.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria,2Z2XY@29|Myxococcales	28221|Deltaproteobacteria	P	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
TLS3_k127_441106_8	589865.DaAHT2_0581	4.009e-18	84.0	2DMHQ@1|root,32RMG@2|Bacteria,1RI3A@1224|Proteobacteria,42V0J@68525|delta/epsilon subdivisions,2WRQ5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Arsenical resistance operon trans-acting repressor ArsD	-	-	-	-	-	-	-	-	-	-	-	-	ArsD
TLS3_k127_441106_6	404589.Anae109_3642	8.571e-48	194.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42RQI@68525|delta/epsilon subdivisions,2WNEC@28221|Deltaproteobacteria,2YUZQ@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
TLS3_k127_441106_1	290397.Adeh_1023	3.452e-197	619.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,42M0Z@68525|delta/epsilon subdivisions,2WK36@28221|Deltaproteobacteria,2Z0TJ@29|Myxococcales	28221|Deltaproteobacteria	P	arsenical-resistance protein	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
TLS3_k127_441106_5	404589.Anae109_3644	3.223e-51	191.0	COG0640@1|root,COG0640@2|Bacteria,1N7I7@1224|Proteobacteria,42VTU@68525|delta/epsilon subdivisions,2WRGJ@28221|Deltaproteobacteria,2YVHK@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
TLS3_k127_441106_2	290397.Adeh_1027	1.36e-120	405.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42MF8@68525|delta/epsilon subdivisions,2WJFH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
TLS3_k127_441106_7	215803.DB30_6485	1.131e-36	155.0	COG2340@1|root,COG2340@2|Bacteria,1N9SZ@1224|Proteobacteria,42Y4A@68525|delta/epsilon subdivisions,2WSXE@28221|Deltaproteobacteria,2YVGZ@29|Myxococcales	28221|Deltaproteobacteria	S	SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains.	-	-	-	-	-	-	-	-	-	-	-	-	CAP
TLS3_k127_441106_0	290397.Adeh_0831	1.14e-258	806.0	COG1012@1|root,COG1012@2|Bacteria,1QWN5@1224|Proteobacteria,43BT3@68525|delta/epsilon subdivisions,2X73T@28221|Deltaproteobacteria,2YU0C@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	pruA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
TLS3_k127_441106_4	404589.Anae109_0892	2.522e-90	309.0	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,43BPM@68525|delta/epsilon subdivisions,2X70W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM secretion protein HlyD family protein	ybhG	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS3_k127_441106_3	290397.Adeh_3112	2.08e-104	342.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42PIB@68525|delta/epsilon subdivisions,2WKFC@28221|Deltaproteobacteria,2Z2W7@29|Myxococcales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	ybhF-N	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
TLS3_k127_4484882_3	290397.Adeh_3945	3.014e-64	239.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2WMJ5@28221|Deltaproteobacteria,2YV59@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
TLS3_k127_4484882_4	404589.Anae109_0479	8.337e-51	206.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,DnaJ
TLS3_k127_4484882_0	290397.Adeh_3947	5.506e-308	956.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,2YZII@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
TLS3_k127_4484882_2	880073.Calab_2195	2.954e-115	390.0	COG1271@1|root,COG2010@1|root,COG1271@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
TLS3_k127_4484882_5	882.DVU_2485	1.07e-46	182.0	COG1271@1|root,COG1271@2|Bacteria,1QXQF@1224|Proteobacteria,42NKJ@68525|delta/epsilon subdivisions,2WKHM@28221|Deltaproteobacteria,2M95S@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	oxidase subunit	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	-
TLS3_k127_4484882_1	404589.Anae109_1735	1.241e-131	430.0	COG0457@1|root,COG3629@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria	1224|Proteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_16,TPR_8,Trans_reg_C
TLS3_k127_4504996_4	690850.Desaf_0959	1.67e-75	262.0	COG2327@1|root,COG2327@2|Bacteria,1R9R8@1224|Proteobacteria,42U55@68525|delta/epsilon subdivisions,2WQGP@28221|Deltaproteobacteria,2MDZ8@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
TLS3_k127_4504996_6	448385.sce1520	8.875e-56	214.0	COG1544@1|root,COG1544@2|Bacteria	2|Bacteria	J	regulation of translation	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
TLS3_k127_4504996_12	1254432.SCE1572_40935	6.612e-14	76.0	COG2204@1|root,COG2204@2|Bacteria,1NABF@1224|Proteobacteria,43C0I@68525|delta/epsilon subdivisions,2X7B5@28221|Deltaproteobacteria,2Z3KD@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_4504996_7	1242864.D187_009351	9.998e-50	195.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X791@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
TLS3_k127_4504996_2	639030.JHVA01000001_gene2023	7.216e-98	344.0	COG3391@1|root,COG3391@2|Bacteria,3Y3TB@57723|Acidobacteria,2JKB3@204432|Acidobacteriia	204432|Acidobacteriia	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
TLS3_k127_4504996_5	452637.Oter_4137	2.485e-57	223.0	COG3336@1|root,COG3336@2|Bacteria	2|Bacteria	G	cytochrome c oxidase	-	-	-	ko:K02351	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
TLS3_k127_4504996_11	1283300.ATXB01000002_gene3051	2.796e-28	120.0	COG3474@1|root,COG3474@2|Bacteria,1N7IW@1224|Proteobacteria,1SG62@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TLS3_k127_4504996_13	861299.J421_0301	2.149e-09	70.0	2E5I0@1|root,3309C@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4504996_8	265072.Mfla_1447	8.256e-47	194.0	COG1845@1|root,COG1845@2|Bacteria,1RG95@1224|Proteobacteria,2VS0Y@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c oxidase subunit III	-	-	-	-	-	-	-	-	-	-	-	-	COX3
TLS3_k127_4504996_0	715451.ambt_09280	1.793e-259	830.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,469VD@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.10.3.10,1.9.3.1	ko:K02274,ko:K02298,ko:K15408	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081,R11335	RC00016,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX1
TLS3_k127_4504996_1	861299.J421_1791	2.033e-103	346.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1ZT3S@142182|Gemmatimonadetes	2|Bacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.9.3.1	ko:K02275,ko:K17223	ko00190,ko00920,ko01100,ko01120,map00190,map00920,map01100,map01120	M00155,M00595	R00081,R10151	RC00016,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
TLS3_k127_4504996_10	265072.Mfla_1450	8.662e-33	142.0	COG2010@1|root,COG2010@2|Bacteria,1RHET@1224|Proteobacteria,2W3EV@28216|Betaproteobacteria,2KP1A@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
TLS3_k127_4504996_3	765698.Mesci_6201	4.676e-91	311.0	COG0834@1|root,COG0834@2|Bacteria,1MWWZ@1224|Proteobacteria,2TU2F@28211|Alphaproteobacteria,43JJK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	ET	PFAM extracellular solute-binding protein, family 3	-	-	-	ko:K16254	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	SBP_bac_3
TLS3_k127_4504996_9	395965.Msil_3387	6.896e-34	131.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,3NCBP@45404|Beijerinckiaceae	28211|Alphaproteobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
TLS3_k127_4534685_0	1157708.KB907453_gene4073	3.004e-174	554.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,2VKYD@28216|Betaproteobacteria,4AAJ6@80864|Comamonadaceae	28216|Betaproteobacteria	K	RNA polymerase sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_4534685_8	404589.Anae109_0604	1.583e-66	230.0	COG3832@1|root,COG3832@2|Bacteria,1MZ7K@1224|Proteobacteria	1224|Proteobacteria	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_4534685_10	1380356.JNIK01000017_gene2859	1.043e-25	111.0	2E4BX@1|root,32Z7H@2|Bacteria,2IM6W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867
TLS3_k127_4534685_9	404589.Anae109_0771	6.528e-40	166.0	2DVJC@1|root,33W5M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4534685_4	1385935.N836_01620	1.098e-88	302.0	COG0655@1|root,COG0655@2|Bacteria,1GB8R@1117|Cyanobacteria,1HDV7@1150|Oscillatoriales	1117|Cyanobacteria	S	Nadph-dependent fmn reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
TLS3_k127_4534685_11	1121438.JNJA01000019_gene2770	7.444e-12	70.0	COG3370@1|root,COG3370@2|Bacteria,1N3DX@1224|Proteobacteria,42UA2@68525|delta/epsilon subdivisions,2WQ2I@28221|Deltaproteobacteria,2MCZA@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
TLS3_k127_4534685_7	452637.Oter_0998	2.245e-72	271.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_4534685_6	290397.Adeh_3099	1.003e-81	276.0	COG1309@1|root,COG1309@2|Bacteria,1R6RX@1224|Proteobacteria,42T50@68525|delta/epsilon subdivisions,2WPVV@28221|Deltaproteobacteria,2YUY1@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
TLS3_k127_4534685_5	404589.Anae109_1019	5.233e-82	284.0	COG1073@1|root,COG1073@2|Bacteria,1MZUA@1224|Proteobacteria,431FI@68525|delta/epsilon subdivisions,2WX1E@28221|Deltaproteobacteria,2YV8K@29|Myxococcales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
TLS3_k127_4534685_1	290397.Adeh_1991	2.485e-134	434.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03086,ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS3_k127_4534685_2	1095769.CAHF01000022_gene362	5.526e-122	412.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2VIVI@28216|Betaproteobacteria,4733C@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	glxR	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
TLS3_k127_4534685_3	1218084.BBJK01000154_gene7643	1.471e-98	329.0	COG3622@1|root,COG3622@2|Bacteria,1MV53@1224|Proteobacteria,2VJ19@28216|Betaproteobacteria,1K3FC@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Belongs to the hyi family	hyi	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
TLS3_k127_4555049_2	290397.Adeh_2119	4.365e-61	214.0	COG0782@1|root,COG0782@2|Bacteria	2|Bacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
TLS3_k127_4555049_1	404589.Anae109_2364	1.397e-66	233.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,42UUN@68525|delta/epsilon subdivisions,2WPZH@28221|Deltaproteobacteria,2YUZ6@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
TLS3_k127_4555049_5	290397.Adeh_2802	7.58e-20	90.0	2EK70@1|root,33DXD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4555049_0	290397.Adeh_2954	1.143e-199	627.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,42PQY@68525|delta/epsilon subdivisions,2WJXE@28221|Deltaproteobacteria,2YUH0@29|Myxococcales	28221|Deltaproteobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroF	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2375	DAHP_synth_1
TLS3_k127_4555049_6	1157708.KB907460_gene1349	2.325e-12	80.0	COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,2VR0I@28216|Betaproteobacteria,4AFQ2@80864|Comamonadaceae	28216|Betaproteobacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4555049_3	290397.Adeh_3148	3.185e-48	180.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_4574000_0	290397.Adeh_3831	2.045e-224	703.0	COG1249@1|root,COG1249@2|Bacteria,1MVVE@1224|Proteobacteria,42Z7G@68525|delta/epsilon subdivisions,2WU0D@28221|Deltaproteobacteria,2YU48@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	sthA	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_4574000_2	404589.Anae109_3943	8.837e-128	414.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,42SPQ@68525|delta/epsilon subdivisions,2WPX1@28221|Deltaproteobacteria,2YWQX@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
TLS3_k127_4574000_1	290397.Adeh_3828	1.14e-141	471.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,42MY5@68525|delta/epsilon subdivisions,2WKST@28221|Deltaproteobacteria,2YUHP@29|Myxococcales	28221|Deltaproteobacteria	E	succinyl-diaminopimelate desuccinylase	dapE2	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
TLS3_k127_4605516_5	404589.Anae109_3410	2.173e-126	413.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,437Y3@68525|delta/epsilon subdivisions,2X380@28221|Deltaproteobacteria,2YURY@29|Myxococcales	28221|Deltaproteobacteria	E	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
TLS3_k127_4605516_1	404589.Anae109_3411	5.513e-282	885.0	COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria	1224|Proteobacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
TLS3_k127_4605516_3	404589.Anae109_3412	3.194e-218	684.0	COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,42MAE@68525|delta/epsilon subdivisions,2WKFF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Xanthine uracil vitamin C permease	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
TLS3_k127_4605516_4	404589.Anae109_3413	4.532e-183	580.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,42N99@68525|delta/epsilon subdivisions,2WJY8@28221|Deltaproteobacteria,2YTVB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
TLS3_k127_4605516_6	404589.Anae109_3415	3.549e-77	267.0	COG2519@1|root,COG2519@2|Bacteria	2|Bacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,SAM_MT,Spermine_synth
TLS3_k127_4605516_0	404589.Anae109_3418	0.0	1320.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YU3Z@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
TLS3_k127_4605516_2	404589.Anae109_3420	3.708e-253	782.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2YUHC@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
TLS3_k127_4626138_3	290397.Adeh_1452	3.341e-74	264.0	COG1409@1|root,COG1409@2|Bacteria,1Q6SY@1224|Proteobacteria,433RH@68525|delta/epsilon subdivisions,2WX9D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
TLS3_k127_4626138_4	404589.Anae109_1682	3.611e-46	183.0	294ZR@1|root,2ZSCK@2|Bacteria	2|Bacteria	S	COG NOG27188 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4626138_0	404589.Anae109_1744	4.071e-222	697.0	COG2195@1|root,COG2195@2|Bacteria,1MUWK@1224|Proteobacteria,42PS0@68525|delta/epsilon subdivisions,2WJU3@28221|Deltaproteobacteria,2YYFX@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M20/M25/M40	-	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
TLS3_k127_4626138_2	404589.Anae109_1751	3.789e-92	312.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TLS3_k127_4626138_5	1280954.HPO_11219	8.807e-20	104.0	COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,2UBR4@28211|Alphaproteobacteria,43YG7@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	COG2076 Membrane transporters of cations and cationic drugs	sugE	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
TLS3_k127_4626138_1	404589.Anae109_2913	1.283e-175	559.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2YU9C@29|Myxococcales	28221|Deltaproteobacteria	L	DbpA RNA binding domain	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
TLS3_k127_4660579_3	290397.Adeh_1139	5.154e-80	267.0	COG1351@1|root,COG1351@2|Bacteria,1Q73I@1224|Proteobacteria,42N3X@68525|delta/epsilon subdivisions,2WN7U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
TLS3_k127_4660579_0	290397.Adeh_1138	1.196e-225	726.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42QUN@68525|delta/epsilon subdivisions,2WN6Q@28221|Deltaproteobacteria,2YU60@29|Myxococcales	28221|Deltaproteobacteria	OU	signal peptide peptidase SppA, 36K type	sppA2	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
TLS3_k127_4660579_1	404589.Anae109_1185	8.445e-207	657.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
TLS3_k127_4660579_2	404589.Anae109_1184	1.554e-183	580.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,42MD7@68525|delta/epsilon subdivisions,2WJH1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,Response_reg
TLS3_k127_4676492_6	1408444.JHYC01000004_gene692	1.256e-24	111.0	COG2706@1|root,COG2706@2|Bacteria,1RB38@1224|Proteobacteria,1SNAF@1236|Gammaproteobacteria,1JE2M@118969|Legionellales	118969|Legionellales	G	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4676492_1	290397.Adeh_4271	1.249e-94	314.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2YV9U@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_4676492_0	404589.Anae109_4424	4.46e-237	769.0	COG1196@1|root,COG1196@2|Bacteria,1QX9X@1224|Proteobacteria,43018@68525|delta/epsilon subdivisions,2WVD9@28221|Deltaproteobacteria,2YW2N@29|Myxococcales	28221|Deltaproteobacteria	D	Domain of unknown function (DUF4175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
TLS3_k127_4676492_5	404589.Anae109_4423	1.77e-25	117.0	COG0308@1|root,COG4783@1|root,COG0308@2|Bacteria,COG4783@2|Bacteria,1RBHC@1224|Proteobacteria,42QWW@68525|delta/epsilon subdivisions,2WMP2@28221|Deltaproteobacteria,2YUU2@29|Myxococcales	28221|Deltaproteobacteria	E	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
TLS3_k127_4676492_2	1242864.D187_001187	1.745e-35	139.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YWPA@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase associated with various cellular activities	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TLS3_k127_4784876_6	445335.CBN_A0062	8.204e-09	57.0	2ERMT@1|root,33J79@2|Bacteria,1VKZE@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4784876_4	483219.LILAB_31460	2.441e-60	219.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2WNAD@28221|Deltaproteobacteria,2YV51@29|Myxococcales	28221|Deltaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
TLS3_k127_4784876_1	404589.Anae109_2574	2.717e-114	376.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,42RFR@68525|delta/epsilon subdivisions,2WJYK@28221|Deltaproteobacteria,2YVIN@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
TLS3_k127_4784876_5	290397.Adeh_2608	5.993e-18	87.0	COG2835@1|root,COG2835@2|Bacteria,1Q1BG@1224|Proteobacteria,42WTN@68525|delta/epsilon subdivisions,2WSI9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0434 family	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
TLS3_k127_4784876_3	290397.Adeh_2610	1.882e-67	248.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
TLS3_k127_4784876_0	404589.Anae109_2578	1.258e-136	442.0	COG2870@1|root,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
TLS3_k127_4784876_2	404589.Anae109_2579	4.602e-107	352.0	COG1560@1|root,COG1560@2|Bacteria,1R03A@1224|Proteobacteria,43CQI@68525|delta/epsilon subdivisions,2X7XZ@28221|Deltaproteobacteria,2Z27Y@29|Myxococcales	28221|Deltaproteobacteria	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
TLS3_k127_4808980_0	290397.Adeh_3640	9.036e-266	852.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2Z2X2@29|Myxococcales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TLS3_k127_4808980_2	404589.Anae109_3767	5.94e-77	288.0	COG1651@1|root,COG1651@2|Bacteria,1MVS2@1224|Proteobacteria	1224|Proteobacteria	O	COG1651 Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
TLS3_k127_4808980_1	404589.Anae109_3768	1.676e-142	464.0	COG0457@1|root,COG0457@2|Bacteria,1R7XY@1224|Proteobacteria,42NFC@68525|delta/epsilon subdivisions,2WMA4@28221|Deltaproteobacteria,2Z18K@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
TLS3_k127_4808980_3	404589.Anae109_3769	3.225e-48	192.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2WN09@28221|Deltaproteobacteria,2YUZJ@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
TLS3_k127_4830991_5	378806.STAUR_3906	7.239e-30	124.0	COG3746@1|root,COG3746@2|Bacteria,1PBWD@1224|Proteobacteria,433TT@68525|delta/epsilon subdivisions,2X3F8@28221|Deltaproteobacteria,2YVU2@29|Myxococcales	28221|Deltaproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4830991_2	290397.Adeh_4006	6.287e-114	373.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria,2YVQ5@29|Myxococcales	28221|Deltaproteobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
TLS3_k127_4830991_0	404589.Anae109_0573	0.0	1196.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2WJG7@28221|Deltaproteobacteria,2YUAP@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
TLS3_k127_4830991_1	502025.Hoch_3806	1.311e-265	856.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,42NS6@68525|delta/epsilon subdivisions,2WKYJ@28221|Deltaproteobacteria,2YU4P@29|Myxococcales	28221|Deltaproteobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
TLS3_k127_4830991_3	1242864.D187_003349	2.217e-59	219.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	-	-	-	ko:K20469	-	-	-	-	ko00000,ko02000	2.A.86.1.7	-	-	AI-2E_transport
TLS3_k127_4830991_6	935840.JAEQ01000003_gene70	2.869e-26	115.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,43H8P@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Pyrrolo-quinoline quinone	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
TLS3_k127_4830991_4	234267.Acid_6912	1.311e-56	213.0	COG4993@1|root,COG4993@2|Bacteria,3Y72Y@57723|Acidobacteria	57723|Acidobacteria	G	PQQ enzyme repeat	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ
TLS3_k127_487361_4	404589.Anae109_0340	1.772e-30	126.0	COG0484@1|root,COG0484@2|Bacteria,1N40E@1224|Proteobacteria,42UFJ@68525|delta/epsilon subdivisions,2WQAY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_487361_1	290397.Adeh_3924	1.749e-156	505.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42PVW@68525|delta/epsilon subdivisions,2WIMX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
TLS3_k127_487361_5	290397.Adeh_0310	6.548e-30	123.0	COG1942@1|root,COG1942@2|Bacteria,1N6WW@1224|Proteobacteria,42V9V@68525|delta/epsilon subdivisions,2WRUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM 4-oxalocrotonate tautomerase family enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
TLS3_k127_487361_2	290397.Adeh_0312	5.309e-130	424.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,42VVS@68525|delta/epsilon subdivisions,2X5WR@28221|Deltaproteobacteria,2YVAQ@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
TLS3_k127_487361_0	502025.Hoch_4095	1.895e-205	645.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,42NYT@68525|delta/epsilon subdivisions,2WIM3@28221|Deltaproteobacteria,2Z34A@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
TLS3_k127_4902200_2	404589.Anae109_1118	8.127e-175	584.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2YUSA@29|Myxococcales	28221|Deltaproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
TLS3_k127_4902200_1	290397.Adeh_1078	1.125e-279	868.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2WJ9G@28221|Deltaproteobacteria,2YUAA@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
TLS3_k127_4902200_0	404589.Anae109_1115	0.0	1004.0	COG1543@1|root,COG1543@2|Bacteria,1R5SN@1224|Proteobacteria,42PSX@68525|delta/epsilon subdivisions,2WU5G@28221|Deltaproteobacteria,2YTTH@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
TLS3_k127_4902200_3	404589.Anae109_1114	9.141e-89	299.0	COG3330@1|root,COG3330@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4912)	-	-	-	ko:K09942	-	-	-	-	ko00000	-	-	-	DUF4912,Rho_N
TLS3_k127_490875_4	404589.Anae109_4478	6.016e-75	262.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,2YUID@29|Myxococcales	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
TLS3_k127_490875_6	290397.Adeh_4331	1.944e-54	199.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	2.7.11.1	ko:K12132,ko:K20543	-	-	-	-	ko00000,ko01000,ko01001,ko02000	1.B.55.3	-	-	AAA_16,NfrA_C,Pkinase,TPR_10,TPR_12,TPR_14,TPR_16,TPR_19,TPR_8
TLS3_k127_490875_3	404589.Anae109_4476	5.263e-141	481.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,2YUQ9@29|Myxococcales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
TLS3_k127_490875_7	290397.Adeh_4329	2.625e-45	186.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,42TM2@68525|delta/epsilon subdivisions,2WQ0U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
TLS3_k127_490875_0	290397.Adeh_4328	0.0	1021.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2YU6B@29|Myxococcales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
TLS3_k127_490875_1	404589.Anae109_4473	3.37e-184	581.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,2YXG3@29|Myxococcales	28221|Deltaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
TLS3_k127_490875_2	290397.Adeh_4326	2.383e-144	478.0	COG0683@1|root,COG0683@2|Bacteria,1R8IG@1224|Proteobacteria,42N7H@68525|delta/epsilon subdivisions,2WIUQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	ABC-type branched-chain amino acid transport	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC,Peripla_BP_6,TPR_16,TPR_6
TLS3_k127_490875_5	290397.Adeh_4325	2.707e-56	205.0	COG0750@1|root,COG0750@2|Bacteria,1QXA9@1224|Proteobacteria,4303D@68525|delta/epsilon subdivisions,2WV7D@28221|Deltaproteobacteria,2YV5D@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
TLS3_k127_4916267_7	326424.FRAAL2392	3.359e-55	196.0	COG1740@1|root,COG1740@2|Bacteria,2GKF2@201174|Actinobacteria,4EU33@85013|Frankiales	201174|Actinobacteria	C	Uptake hydrogenase small subunit (Hydrogenlyase) (Membrane-bound hydrogenase small subunit)	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
TLS3_k127_4916267_4	28042.GU90_07290	5.128e-89	307.0	COG0378@1|root,COG0378@2|Bacteria,2HP34@201174|Actinobacteria,4DYGC@85010|Pseudonocardiales	201174|Actinobacteria	KO	TIGRFAM Hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
TLS3_k127_4916267_9	106370.Francci3_1937	2.579e-22	106.0	COG0375@1|root,COG0375@2|Bacteria,2IMJK@201174|Actinobacteria,4EW8S@85013|Frankiales	201174|Actinobacteria	S	Hydrogenase nickel incorporation protein hypA	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
TLS3_k127_4916267_10	234267.Acid_6551	2.212e-20	102.0	COG0298@1|root,COG0298@2|Bacteria,3Y5NM@57723|Acidobacteria	57723|Acidobacteria	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
TLS3_k127_4916267_1	886293.Sinac_4490	4.19e-176	564.0	COG0409@1|root,COG0409@2|Bacteria,2IYJ2@203682|Planctomycetes	203682|Planctomycetes	O	Hydrogenase formation hypA family	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
TLS3_k127_4916267_6	234267.Acid_6553	1.854e-61	233.0	COG0279@1|root,COG0279@2|Bacteria,3Y4UX@57723|Acidobacteria	57723|Acidobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
TLS3_k127_4916267_3	517417.Cpar_1633	2.068e-121	400.0	COG0309@1|root,COG0309@2|Bacteria,1FD9M@1090|Chlorobi	1090|Chlorobi	O	hydrogenase expression formation protein HypE	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
TLS3_k127_4916267_5	404589.Anae109_1654	6.079e-65	226.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,42SN0@68525|delta/epsilon subdivisions,2WPY6@28221|Deltaproteobacteria,2Z0UJ@29|Myxococcales	28221|Deltaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
TLS3_k127_4916267_2	404589.Anae109_2819	5.367e-151	484.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,42MXJ@68525|delta/epsilon subdivisions,2WKAC@28221|Deltaproteobacteria,2YYQW@29|Myxococcales	28221|Deltaproteobacteria	C	Alcohol dehydrogenase GroES domain protein	-	-	-	ko:K19745	ko00640,ko01100,map00640,map01100	-	R00919	RC00095	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_4916267_0	290397.Adeh_3108	0.0	1120.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,42MUY@68525|delta/epsilon subdivisions,2X6WF@28221|Deltaproteobacteria,2YWNJ@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M3	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
TLS3_k127_500560_0	404589.Anae109_3687	3.943e-202	636.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2YUGG@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
TLS3_k127_500560_3	404589.Anae109_3686	1.26e-68	249.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,42TVX@68525|delta/epsilon subdivisions,2WP4F@28221|Deltaproteobacteria,2YV7H@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF4124,SLT
TLS3_k127_500560_1	404589.Anae109_3685	6.179e-93	330.0	COG0457@1|root,COG2013@1|root,COG0457@2|Bacteria,COG2013@2|Bacteria,1NHMN@1224|Proteobacteria,43CDQ@68525|delta/epsilon subdivisions,2X7PM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
TLS3_k127_500560_2	290397.Adeh_3563	3.698e-72	270.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,42QQ4@68525|delta/epsilon subdivisions,2WQGH@28221|Deltaproteobacteria,2YVBE@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
TLS3_k127_5046433_1	290397.Adeh_1100	1.726e-309	957.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,2YUJG@29|Myxococcales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
TLS3_k127_5046433_13	404589.Anae109_1138	5.047e-80	271.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2WQ0W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
TLS3_k127_5046433_8	290397.Adeh_1098	1.685e-117	391.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,2YV01@29|Myxococcales	28221|Deltaproteobacteria	J	FtsJ-like methyltransferase	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
TLS3_k127_5046433_0	404589.Anae109_1136	2.952e-317	987.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
TLS3_k127_5046433_10	404589.Anae109_1135	3.833e-102	351.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2WIY4@28221|Deltaproteobacteria,2YV7Y@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	crtE	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
TLS3_k127_5046433_15	290397.Adeh_1095	2.99e-64	226.0	COG0745@1|root,COG0745@2|Bacteria,1RKDZ@1224|Proteobacteria,42SJ2@68525|delta/epsilon subdivisions,2WPC9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	regulator	-	-	-	ko:K07773	ko02020,ko02026,map02020,map02026	M00456	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
TLS3_k127_5046433_20	290397.Adeh_1094	2.135e-23	116.0	COG1722@1|root,COG1722@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
TLS3_k127_5046433_4	290397.Adeh_1093	1.824e-190	620.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2WJI6@28221|Deltaproteobacteria,2YV21@29|Myxococcales	28221|Deltaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
TLS3_k127_5046433_14	404589.Anae109_1131	2.84e-79	287.0	COG1877@1|root,COG1877@2|Bacteria,1Q1R2@1224|Proteobacteria,42U7I@68525|delta/epsilon subdivisions,2WQZE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
TLS3_k127_5046433_6	404589.Anae109_1130	7.204e-134	467.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2WMJ2@28221|Deltaproteobacteria,2Z21X@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
TLS3_k127_5046433_2	290397.Adeh_1089	4.499e-250	776.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,42M87@68525|delta/epsilon subdivisions,2WMB0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
TLS3_k127_5046433_5	290397.Adeh_1088	5.84e-164	527.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2WJZK@28221|Deltaproteobacteria,2YTSB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
TLS3_k127_5046433_19	290397.Adeh_1087	3.304e-26	126.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,42VE5@68525|delta/epsilon subdivisions,2WR8T@28221|Deltaproteobacteria,2YW4H@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
TLS3_k127_5046433_9	404589.Anae109_1125	8.454e-116	377.0	COG3494@1|root,COG3494@2|Bacteria,1MWTH@1224|Proteobacteria,42P40@68525|delta/epsilon subdivisions,2WK7K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
TLS3_k127_5046433_12	290397.Adeh_1085	8.64e-99	337.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2WJVP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
TLS3_k127_5046433_17	404589.Anae109_1123	4.962e-48	195.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,42SCN@68525|delta/epsilon subdivisions,2WP3E@28221|Deltaproteobacteria,2YVDF@29|Myxococcales	28221|Deltaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
TLS3_k127_5046433_7	404589.Anae109_1122	2.038e-131	427.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
TLS3_k127_5046433_18	404589.Anae109_1121	7.985e-34	137.0	COG2825@1|root,COG2825@2|Bacteria,1MZVJ@1224|Proteobacteria,42VH3@68525|delta/epsilon subdivisions,2WP6K@28221|Deltaproteobacteria,2YVZ7@29|Myxococcales	28221|Deltaproteobacteria	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TLS3_k127_5046433_3	378806.STAUR_5578	1.04e-227	730.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2YUN3@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
TLS3_k127_5046433_11	404589.Anae109_1119	1.683e-100	337.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,2YURX@29|Myxococcales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
TLS3_k127_5046433_16	290397.Adeh_1079	1.172e-48	175.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2YUSA@29|Myxococcales	28221|Deltaproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
TLS3_k127_5071141_0	404589.Anae109_1329	0.0	1105.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2WJEV@28221|Deltaproteobacteria,2YTWY@29|Myxococcales	28221|Deltaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
TLS3_k127_5071141_1	404589.Anae109_1336	3.682e-277	861.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42M8D@68525|delta/epsilon subdivisions,2WJ6E@28221|Deltaproteobacteria,2YWFY@29|Myxococcales	28221|Deltaproteobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C,Fer2_BFD
TLS3_k127_5071141_2	404589.Anae109_1337	1.3e-39	169.0	COG3075@1|root,COG3075@2|Bacteria,1MU3K@1224|Proteobacteria,42Q09@68525|delta/epsilon subdivisions,2WKE0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	glpB	-	1.1.5.3	ko:K00112	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
TLS3_k127_5079766_0	404589.Anae109_0502	3.888e-195	614.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria,2YXS2@29|Myxococcales	28221|Deltaproteobacteria	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
TLS3_k127_5079766_3	404589.Anae109_0504	6.345e-44	177.0	2AQXT@1|root,31G6D@2|Bacteria,1QACF@1224|Proteobacteria,434ZG@68525|delta/epsilon subdivisions,2WZA9@28221|Deltaproteobacteria,2Z1PG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
TLS3_k127_5079766_1	290397.Adeh_3929	2.694e-142	461.0	COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria,43791@68525|delta/epsilon subdivisions,2X9X0@28221|Deltaproteobacteria,2YZTI@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the FPG family	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
TLS3_k127_5079766_2	1254432.SCE1572_18340	3.823e-131	426.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,2YTUX@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_5097180_4	404589.Anae109_0159	7.351e-118	385.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
TLS3_k127_5097180_0	290397.Adeh_0153	3.47e-281	874.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria,2YY2C@29|Myxococcales	28221|Deltaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
TLS3_k127_5097180_9	290397.Adeh_0152	1.292e-38	145.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,42V5C@68525|delta/epsilon subdivisions,2WRC4@28221|Deltaproteobacteria,2Z1YQ@29|Myxococcales	28221|Deltaproteobacteria	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
TLS3_k127_5097180_5	290397.Adeh_0151	2.969e-86	305.0	COG3716@1|root,COG3716@2|Bacteria,1P02J@1224|Proteobacteria,42RPH@68525|delta/epsilon subdivisions,2WNQI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM PTS system mannose fructose sorbose family IID component	-	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
TLS3_k127_5097180_6	404589.Anae109_0155	8.704e-59	211.0	COG3715@1|root,COG3715@2|Bacteria,1RHFJ@1224|Proteobacteria,42SZF@68525|delta/epsilon subdivisions,2WPSS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PTS system	-	-	-	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor
TLS3_k127_5097180_7	404589.Anae109_0154	1.314e-54	195.0	COG3444@1|root,COG3444@2|Bacteria,1R4ES@1224|Proteobacteria,42VCG@68525|delta/epsilon subdivisions,2WRN8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM PTS system sorbose subfamily IIB component	-	-	2.7.1.191	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	PTSIIB_sorb
TLS3_k127_5097180_8	290397.Adeh_0148	1.034e-47	179.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,42SST@68525|delta/epsilon subdivisions,2WPWN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM PTS system fructose subfamily IIA component	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
TLS3_k127_5097180_2	404589.Anae109_0152	2.623e-132	444.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,42MZM@68525|delta/epsilon subdivisions,2WJG6@28221|Deltaproteobacteria,2YV1E@29|Myxococcales	28221|Deltaproteobacteria	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
TLS3_k127_5097180_1	404589.Anae109_0151	1.639e-182	573.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,42P9W@68525|delta/epsilon subdivisions,2WK54@28221|Deltaproteobacteria,2YUU0@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
TLS3_k127_5097180_3	404589.Anae109_0150	5.789e-131	422.0	COG2404@1|root,COG2404@2|Bacteria,1QW0R@1224|Proteobacteria,43BQN@68525|delta/epsilon subdivisions,2X71Q@28221|Deltaproteobacteria,2YUZT@29|Myxococcales	28221|Deltaproteobacteria	S	COG0618 Exopolyphosphatase-related proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5104134_3	290397.Adeh_3395	1.333e-84	289.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,42Q52@68525|delta/epsilon subdivisions,2WJ3S@28221|Deltaproteobacteria,2Z0HR@29|Myxococcales	28221|Deltaproteobacteria	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
TLS3_k127_5104134_1	404589.Anae109_3461	0.0	1205.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WIQG@28221|Deltaproteobacteria,2YUFQ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
TLS3_k127_5104134_2	404589.Anae109_3462	2.253e-114	381.0	COG0628@1|root,COG0628@2|Bacteria,1PTH3@1224|Proteobacteria,42T9W@68525|delta/epsilon subdivisions,2WPRE@28221|Deltaproteobacteria,2YUY8@29|Myxococcales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS3_k127_5104134_5	215803.DB30_6472	4.385e-71	250.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria,2YVWV@29|Myxococcales	28221|Deltaproteobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
TLS3_k127_5104134_4	290397.Adeh_3399	1.513e-72	250.0	COG0625@1|root,COG0625@2|Bacteria,1NX28@1224|Proteobacteria	1224|Proteobacteria	O	Glutathione S-transferase	yfcF	GO:0000302,GO:0003674,GO:0003824,GO:0004364,GO:0006950,GO:0006979,GO:0008150,GO:0009636,GO:0010035,GO:0016740,GO:0016765,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050896,GO:1901700	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	iECW_1372.ECW_m2490,iWFL_1372.ECW_m2490	GST_C_4,GST_N,GST_N_3
TLS3_k127_5104134_7	290397.Adeh_3402	5.143e-28	124.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
TLS3_k127_5104134_0	404589.Anae109_3468	0.0	1300.0	COG4581@1|root,COG4581@2|Bacteria,1QUPR@1224|Proteobacteria,42NSH@68525|delta/epsilon subdivisions,2WKD7@28221|Deltaproteobacteria,2YUGZ@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,DUF3516,Helicase_C
TLS3_k127_5104134_6	404589.Anae109_4402	1.991e-43	164.0	COG4427@1|root,COG4427@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
TLS3_k127_510735_2	404589.Anae109_0380	3.635e-162	540.0	COG1651@1|root,COG1651@2|Bacteria,1RKYF@1224|Proteobacteria,42T64@68525|delta/epsilon subdivisions,2WP82@28221|Deltaproteobacteria,2YU4W@29|Myxococcales	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
TLS3_k127_510735_5	290397.Adeh_4046	2.259e-30	123.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,42VCF@68525|delta/epsilon subdivisions,2WRI6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
TLS3_k127_510735_1	404589.Anae109_0384	9.135e-179	580.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,42MQ9@68525|delta/epsilon subdivisions,2WJPN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Thiamine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,ThiI
TLS3_k127_510735_0	404589.Anae109_0385	0.0	1424.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2YU3T@29|Myxococcales	28221|Deltaproteobacteria	G	pyruvate phosphate dikinase	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
TLS3_k127_510735_3	404589.Anae109_0386	2.536e-140	459.0	COG0768@1|root,COG0768@2|Bacteria,1R7A0@1224|Proteobacteria,42MJC@68525|delta/epsilon subdivisions,2WJZ2@28221|Deltaproteobacteria,2YV14@29|Myxococcales	28221|Deltaproteobacteria	M	Cell division protein FtsI penicillin-binding protein 2	pbp4	-	-	-	-	-	-	-	-	-	-	-	Transpeptidase
TLS3_k127_510735_4	404589.Anae109_0387	1.441e-128	421.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,DnaJ
TLS3_k127_5166206_2	404589.Anae109_4346	3.849e-37	150.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria,2YVNJ@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
TLS3_k127_5166206_1	290397.Adeh_4198	3.405e-50	183.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,42RES@68525|delta/epsilon subdivisions,2WSB9@28221|Deltaproteobacteria,2YVT4@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
TLS3_k127_5166206_0	404589.Anae109_4348	3.28e-226	705.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2YUFG@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF-2	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
TLS3_k127_5187218_0	344747.PM8797T_02569	3.98e-146	468.0	COG0843@1|root,COG0843@2|Bacteria,2J2GN@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K15408	ko00190,map00190	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX1
TLS3_k127_5187218_1	472759.Nhal_3041	2.769e-111	379.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,1X12V@135613|Chromatiales	135613|Chromatiales	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cytochrom_C
TLS3_k127_5187218_2	1242864.D187_003348	9.193e-75	259.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,HYR,Laminin_G_3,Phosphodiest
TLS3_k127_5198822_2	290397.Adeh_1892	3.501e-101	332.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,43BC6@68525|delta/epsilon subdivisions,2X255@28221|Deltaproteobacteria,2YY92@29|Myxococcales	28221|Deltaproteobacteria	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
TLS3_k127_5198822_8	518766.Rmar_2305	8.579e-73	272.0	COG3174@1|root,COG3174@2|Bacteria,4NKP6@976|Bacteroidetes,1FJWC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
TLS3_k127_5198822_1	404589.Anae109_2912	7.756e-104	344.0	COG0524@1|root,COG0524@2|Bacteria,1Q41R@1224|Proteobacteria,439VB@68525|delta/epsilon subdivisions,2X596@28221|Deltaproteobacteria,2Z0A8@29|Myxococcales	28221|Deltaproteobacteria	H	pfkB family carbohydrate kinase	-	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
TLS3_k127_5198822_4	1173021.ALWA01000038_gene1711	3.004e-86	301.0	COG1621@1|root,COG1621@2|Bacteria,1GABT@1117|Cyanobacteria	1117|Cyanobacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5198822_11	483219.LILAB_16725	3.928e-66	235.0	COG0300@1|root,COG0300@2|Bacteria,1R735@1224|Proteobacteria,43BK7@68525|delta/epsilon subdivisions,2X5W4@28221|Deltaproteobacteria,2Z37Z@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_5198822_0	404589.Anae109_2747	3.044e-283	894.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2WPT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
TLS3_k127_5198822_3	404589.Anae109_0545	1.132e-97	336.0	COG1612@1|root,COG1612@2|Bacteria,1PV6F@1224|Proteobacteria,4303Y@68525|delta/epsilon subdivisions,2WVAK@28221|Deltaproteobacteria,2YUJ2@29|Myxococcales	28221|Deltaproteobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
TLS3_k127_5198822_7	1297742.A176_02231	1.474e-74	251.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42UDS@68525|delta/epsilon subdivisions,2WPGE@28221|Deltaproteobacteria,2YV4M@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
TLS3_k127_5198822_5	360910.BAV0486	1.005e-80	277.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2W0AR@28216|Betaproteobacteria,3T33S@506|Alcaligenaceae	28216|Betaproteobacteria	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
TLS3_k127_5198822_9	1125863.JAFN01000001_gene1331	4.009e-72	251.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,42YQS@68525|delta/epsilon subdivisions,2WUCI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
TLS3_k127_5198822_10	696281.Desru_0489	1.245e-69	254.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,24EJ5@186801|Clostridia,260XN@186807|Peptococcaceae	186801|Clostridia	U	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
TLS3_k127_5198822_6	243231.GSU2006	4.017e-79	273.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
TLS3_k127_5198822_12	768710.DesyoDRAFT_1663	5.773e-28	120.0	COG0683@1|root,COG0683@2|Bacteria,1V4XA@1239|Firmicutes,24JG7@186801|Clostridia,261AP@186807|Peptococcaceae	186801|Clostridia	E	PFAM Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
TLS3_k127_5207152_4	290397.Adeh_4220	2.924e-79	268.0	COG2872@1|root,COG2872@2|Bacteria,1MY0P@1224|Proteobacteria	1224|Proteobacteria	S	Related to alanyl-tRNA synthetase HxxxH domain	-	-	6.1.1.7	ko:K01872,ko:K07050	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
TLS3_k127_5207152_7	1242864.D187_000798	2.386e-34	139.0	COG2215@1|root,COG2215@2|Bacteria,1QBWR@1224|Proteobacteria,43E6W@68525|delta/epsilon subdivisions,2WZW2@28221|Deltaproteobacteria,2Z2V8@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5207152_5	290397.Adeh_2986	2.657e-76	268.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,438ES@68525|delta/epsilon subdivisions,2X3PR@28221|Deltaproteobacteria,2YWSV@29|Myxococcales	28221|Deltaproteobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
TLS3_k127_5207152_0	483219.LILAB_26095	0.0	1091.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2YUAS@29|Myxococcales	28221|Deltaproteobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
TLS3_k127_5207152_2	404589.Anae109_4391	1.865e-209	664.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2YWP2@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsA	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
TLS3_k127_5207152_6	404589.Anae109_2910	6.037e-70	244.0	COG2264@1|root,COG2264@2|Bacteria,1R03E@1224|Proteobacteria	1224|Proteobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5207152_1	404589.Anae109_0192	4.28e-246	779.0	COG3083@1|root,COG3083@2|Bacteria,1MX6X@1224|Proteobacteria,42R7V@68525|delta/epsilon subdivisions,2WN3A@28221|Deltaproteobacteria,2Z3GU@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3413)	-	-	-	ko:K07014	-	-	-	-	ko00000	-	-	-	DUF3413,Sulfatase
TLS3_k127_5207152_3	404589.Anae109_1597	1.073e-123	405.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X7MY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
TLS3_k127_5220284_7	290397.Adeh_3836	4.312e-34	141.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
TLS3_k127_5220284_0	404589.Anae109_3950	6.545e-215	679.0	COG2271@1|root,COG2271@2|Bacteria,1RJD2@1224|Proteobacteria	1224|Proteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_5220284_8	404589.Anae109_3953	1.404e-25	121.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,42V3S@68525|delta/epsilon subdivisions,2WYEM@28221|Deltaproteobacteria,2Z2JC@29|Myxococcales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
TLS3_k127_5220284_1	404589.Anae109_3954	1.643e-117	385.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,42MNY@68525|delta/epsilon subdivisions,2WJ6C@28221|Deltaproteobacteria,2YV0G@29|Myxococcales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
TLS3_k127_5220284_4	404589.Anae109_3955	1.761e-72	250.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,42TXX@68525|delta/epsilon subdivisions,2WQBC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4,Peptidase_S15
TLS3_k127_5220284_2	1297863.APJF01000029_gene1398	2.548e-106	352.0	COG0583@1|root,COG0583@2|Bacteria,1N8HZ@1224|Proteobacteria,2TV4S@28211|Alphaproteobacteria,3JRRM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	MA20_36470	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS3_k127_5220284_3	1297863.APJF01000029_gene1397	9.591e-101	343.0	COG0477@1|root,COG2814@2|Bacteria,1MW6T@1224|Proteobacteria,2U1KC@28211|Alphaproteobacteria,3JU5T@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EGP	Uncharacterised MFS-type transporter YbfB	yjiJ	-	-	-	-	-	-	-	-	-	-	-	MFS_4
TLS3_k127_5220284_6	666684.AfiDRAFT_3454	7.182e-58	226.0	COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,2TQSD@28211|Alphaproteobacteria,3JUX0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
TLS3_k127_5220284_5	404589.Anae109_3957	3.724e-64	221.0	COG0312@1|root,COG0312@2|Bacteria,1RBJZ@1224|Proteobacteria,42YBE@68525|delta/epsilon subdivisions,2WUP7@28221|Deltaproteobacteria,2YZ4Y@29|Myxococcales	28221|Deltaproteobacteria	L	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
TLS3_k127_5223563_3	290397.Adeh_3594	1.163e-64	229.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2YUQN@29|Myxococcales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
TLS3_k127_5223563_4	290397.Adeh_3593	1.304e-49	178.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2YVK0@29|Myxococcales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
TLS3_k127_5223563_1	290397.Adeh_3592	3.075e-76	261.0	2DKHM@1|root,309GY@2|Bacteria,1RFJ6@1224|Proteobacteria,43BG3@68525|delta/epsilon subdivisions,2X6UE@28221|Deltaproteobacteria,2Z3CV@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5223563_2	404589.Anae109_3712	1.735e-72	263.0	2AI7D@1|root,318MR@2|Bacteria,1Q0MU@1224|Proteobacteria,436RD@68525|delta/epsilon subdivisions,2X1E8@28221|Deltaproteobacteria,2YW7E@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5223563_5	290397.Adeh_3590	2.681e-43	159.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,42V07@68525|delta/epsilon subdivisions,2WRQ6@28221|Deltaproteobacteria,2YW65@29|Myxococcales	28221|Deltaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
TLS3_k127_5223563_0	290397.Adeh_3588	5.874e-144	462.0	COG1484@1|root,COG1484@2|Bacteria	2|Bacteria	L	DNA-dependent DNA replication	dnaC	-	3.4.21.53	ko:K02315,ko:K04076	-	-	-	-	ko00000,ko01000,ko01002,ko03032	-	-	-	AAA,IstB_IS21,Lon_C
TLS3_k127_5242943_1	1254432.SCE1572_23945	6.959e-213	672.0	COG2159@1|root,COG2159@2|Bacteria,1PZGI@1224|Proteobacteria,435YS@68525|delta/epsilon subdivisions,2X9TW@28221|Deltaproteobacteria,2Z1SH@29|Myxococcales	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
TLS3_k127_5242943_4	404589.Anae109_4300	1.074e-47	181.0	COG0599@1|root,COG0599@2|Bacteria,1RK66@1224|Proteobacteria	1224|Proteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
TLS3_k127_5242943_3	290397.Adeh_0206	7.144e-58	208.0	COG0477@1|root,COG0477@2|Bacteria,1NS3F@1224|Proteobacteria,42X52@68525|delta/epsilon subdivisions,2WUPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_5242943_0	404589.Anae109_1428	1.058e-214	680.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Pyridoxal-dependent decarboxylase	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
TLS3_k127_5242943_5	448385.sce5336	1.988e-31	143.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_5242943_2	1242864.D187_001058	5.476e-123	414.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1NVJB@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA
TLS3_k127_5254246_1	404589.Anae109_2392	9.24e-322	998.0	COG0454@1|root,COG1022@1|root,COG0456@2|Bacteria,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
TLS3_k127_5254246_4	290397.Adeh_1436	1.019e-189	632.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2X1XD@28221|Deltaproteobacteria,2YWND@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.14	ko:K01655	ko00300,ko00620,ko01100,ko01120,ko01130,ko01210,ko01230,map00300,map00620,map01100,map01120,map01130,map01210,map01230	M00030,M00433	R00271	RC00004,RC00067,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
TLS3_k127_5254246_13	404589.Anae109_1750	2.626e-70	243.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
TLS3_k127_5254246_6	290397.Adeh_3719	2.075e-151	486.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WKF9@28221|Deltaproteobacteria,2YXTE@29|Myxococcales	28221|Deltaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	namA	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
TLS3_k127_5254246_3	404589.Anae109_3801	2.19e-199	634.0	COG0539@1|root,COG0539@2|Bacteria,1N2EJ@1224|Proteobacteria,42NXS@68525|delta/epsilon subdivisions,2WJ0A@28221|Deltaproteobacteria,2YV19@29|Myxococcales	28221|Deltaproteobacteria	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
TLS3_k127_5254246_8	404589.Anae109_3799	2.74e-125	414.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	yebA5	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_5254246_2	290397.Adeh_3675	1.196e-231	732.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,42MKI@68525|delta/epsilon subdivisions,2WIQJ@28221|Deltaproteobacteria,2YUFZ@29|Myxococcales	28221|Deltaproteobacteria	G	4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase	treZ	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
TLS3_k127_5254246_0	404589.Anae109_3803	0.0	1030.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,42PRT@68525|delta/epsilon subdivisions,2WIWH@28221|Deltaproteobacteria,2YU1K@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2638	PEPCK_C,PEPCK_N
TLS3_k127_5254246_14	290397.Adeh_3677	4.818e-68	247.0	COG3332@1|root,COG3332@2|Bacteria,1PUN1@1224|Proteobacteria,434TB@68525|delta/epsilon subdivisions,2WZ4B@28221|Deltaproteobacteria,2Z1AV@29|Myxococcales	28221|Deltaproteobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
TLS3_k127_5254246_16	404589.Anae109_3805	1.968e-40	165.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	DUF971
TLS3_k127_5254246_19	530564.Psta_1560	1.469e-19	101.0	2EW1S@1|root,33PF1@2|Bacteria,2J1T5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5254246_12	404589.Anae109_3806	1.572e-73	260.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	3.6.1.11,3.6.1.40	ko:K01524,ko:K06950	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,HD_5
TLS3_k127_5254246_15	404589.Anae109_3807	3.331e-62	241.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,42SJ8@68525|delta/epsilon subdivisions,2WP5B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
TLS3_k127_5254246_9	290397.Adeh_3681	5.051e-121	394.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,42N3J@68525|delta/epsilon subdivisions,2WJ19@28221|Deltaproteobacteria,2YUVT@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
TLS3_k127_5254246_7	404589.Anae109_3809	3.711e-138	449.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,2YU2N@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
TLS3_k127_5254246_11	290397.Adeh_3683	4.955e-92	307.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria	1224|Proteobacteria	F	Deoxynucleoside kinase	dgk	-	-	-	-	-	-	-	-	-	-	-	dNK
TLS3_k127_5254246_10	290397.Adeh_3685	1.781e-104	361.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,42QAC@68525|delta/epsilon subdivisions,2WN8H@28221|Deltaproteobacteria,2Z0N2@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
TLS3_k127_5254246_5	290397.Adeh_3687	2.147e-165	523.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,2YTSN@29|Myxococcales	28221|Deltaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
TLS3_k127_5275381_0	290397.Adeh_0695	1.013e-244	763.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,2YUJ4@29|Myxococcales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
TLS3_k127_5275381_1	378806.STAUR_6321	9.803e-189	613.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,2YTXT@29|Myxococcales	28221|Deltaproteobacteria	J	Ribonuclease E/G family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
TLS3_k127_5285381_10	1201290.M902_0329	8.9e-13	68.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,42NI7@68525|delta/epsilon subdivisions,2MT2N@213481|Bdellovibrionales,2WNPX@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS3_k127_5285381_3	290397.Adeh_1683	1.462e-121	407.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,42SVD@68525|delta/epsilon subdivisions,2WPFX@28221|Deltaproteobacteria,2Z010@29|Myxococcales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
TLS3_k127_5285381_4	290397.Adeh_1684	5.491e-115	402.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,2YV06@29|Myxococcales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
TLS3_k127_5285381_1	404589.Anae109_2119	5.909e-172	543.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2WJI2@28221|Deltaproteobacteria,2YV60@29|Myxococcales	28221|Deltaproteobacteria	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
TLS3_k127_5285381_7	404589.Anae109_2118	1.075e-70	245.0	COG1994@1|root,COG1994@2|Bacteria,1N531@1224|Proteobacteria,43AZN@68525|delta/epsilon subdivisions,2X6DV@28221|Deltaproteobacteria,2YVCV@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
TLS3_k127_5285381_2	290397.Adeh_1687	1.59e-128	417.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,2YWUR@29|Myxococcales	28221|Deltaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
TLS3_k127_5285381_6	404589.Anae109_2116	1.585e-108	366.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42QSV@68525|delta/epsilon subdivisions,2WMZ5@28221|Deltaproteobacteria,2YVAC@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the SUA5 family	yrdC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
TLS3_k127_5285381_8	378806.STAUR_4384	7.529e-42	159.0	COG3729@1|root,COG3729@2|Bacteria,1NEPC@1224|Proteobacteria,439SW@68525|delta/epsilon subdivisions,2X55X@28221|Deltaproteobacteria,2Z05T@29|Myxococcales	28221|Deltaproteobacteria	S	Small hydrophilic plant seed protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_5
TLS3_k127_5285381_5	404589.Anae109_2113	1.814e-110	366.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,431DF@68525|delta/epsilon subdivisions,2WW95@28221|Deltaproteobacteria,2Z1YE@29|Myxococcales	28221|Deltaproteobacteria	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
TLS3_k127_5285381_0	404589.Anae109_2112	1.601e-257	803.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,2YU3A@29|Myxococcales	28221|Deltaproteobacteria	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
TLS3_k127_5291427_3	404589.Anae109_4485	3.797e-63	222.0	COG0711@1|root,COG0711@2|Bacteria	2|Bacteria	C	ATP synthesis coupled proton transport	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
TLS3_k127_5291427_5	404589.Anae109_4486	2.76e-24	118.0	COG0636@1|root,COG0636@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110,ko:K02124	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157,M00159	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1,3.A.2.2,3.A.2.3	-	iHN637.CLJU_RS01165	ATP-synt_C
TLS3_k127_5291427_1	290397.Adeh_4340	3.233e-147	485.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria	1224|Proteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
TLS3_k127_5291427_2	290397.Adeh_4343	2.816e-82	286.0	COG0520@1|root,COG0520@2|Bacteria,1QU0N@1224|Proteobacteria,42YS3@68525|delta/epsilon subdivisions,2WU59@28221|Deltaproteobacteria,2YTT1@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
TLS3_k127_5291427_0	404589.Anae109_4491	2.528e-212	664.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,42MBF@68525|delta/epsilon subdivisions,2WJQ2@28221|Deltaproteobacteria,2YU3Q@29|Myxococcales	28221|Deltaproteobacteria	H	Aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS3_k127_5305685_1	404589.Anae109_3020	5.377e-79	266.0	COG3639@1|root,COG3639@2|Bacteria,1N3HU@1224|Proteobacteria,43AKI@68525|delta/epsilon subdivisions,2WQEI@28221|Deltaproteobacteria,2YYUD@29|Myxococcales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
TLS3_k127_5305685_0	290397.Adeh_0881	8.001e-149	477.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WKYT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
TLS3_k127_5305685_4	404589.Anae109_0934	8.634e-36	140.0	COG1585@1|root,COG1585@2|Bacteria,1PJH9@1224|Proteobacteria,42WNG@68525|delta/epsilon subdivisions,2WRM8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
TLS3_k127_5305685_2	452637.Oter_1314	2.301e-45	182.0	COG5507@1|root,COG5507@2|Bacteria,46VQ8@74201|Verrucomicrobia,3K9QM@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1428)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1428
TLS3_k127_5305685_6	340177.Cag_0137	1.493e-11	74.0	COG0204@1|root,COG0204@2|Bacteria,1FDPA@1090|Chlorobi	1090|Chlorobi	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TLS3_k127_5305685_3	215803.DB30_8793	8.259e-39	162.0	COG4251@1|root,COG4251@2|Bacteria,1N0FI@1224|Proteobacteria,438UR@68525|delta/epsilon subdivisions,2X9J0@28221|Deltaproteobacteria,2YXU1@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_5316467_1	1242864.D187_002314	3.311e-126	424.0	COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,43DHS@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	TonB dependent receptor	yncD	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
TLS3_k127_5316467_0	269799.Gmet_0208	2.036e-162	529.0	2C19K@1|root,33PMS@2|Bacteria,1NSP6@1224|Proteobacteria,42YKB@68525|delta/epsilon subdivisions,2WTSZ@28221|Deltaproteobacteria,43TR8@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5316467_2	502025.Hoch_6389	5.144e-20	93.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
TLS3_k127_5337619_21	290397.Adeh_2193	7.601e-20	89.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42RFX@68525|delta/epsilon subdivisions,2WN92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
TLS3_k127_5337619_14	404589.Anae109_1163	3.712e-56	199.0	COG1051@1|root,COG1051@2|Bacteria,1QUM0@1224|Proteobacteria,42SY6@68525|delta/epsilon subdivisions,2WP3N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
TLS3_k127_5337619_17	335543.Sfum_1996	6.214e-40	160.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2MQCK@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
TLS3_k127_5337619_7	404589.Anae109_1161	1.117e-115	387.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2YV9N@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
TLS3_k127_5337619_11	290397.Adeh_1120	1.542e-85	287.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1RGUX@1224|Proteobacteria,437BZ@68525|delta/epsilon subdivisions,2WQNB@28221|Deltaproteobacteria,2YVJC@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
TLS3_k127_5337619_20	290397.Adeh_1119	1.407e-29	132.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,Hpt,PAS_3,PAS_4,Response_reg
TLS3_k127_5337619_8	290397.Adeh_1118	9.551e-105	349.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42T7G@68525|delta/epsilon subdivisions,2X75V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HD,HD_5,sCache_3_2
TLS3_k127_5337619_13	404589.Anae109_1156	4.82e-61	219.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,42USC@68525|delta/epsilon subdivisions,2WQMY@28221|Deltaproteobacteria,2Z2ZG@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
TLS3_k127_5337619_6	404589.Anae109_1154	5.742e-119	393.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
TLS3_k127_5337619_10	290397.Adeh_1113	3.065e-86	308.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,42R3K@68525|delta/epsilon subdivisions,2WM8S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
TLS3_k127_5337619_3	404589.Anae109_1151	2.047e-167	551.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria,2YUIU@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the SAICAR synthetase family	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
TLS3_k127_5337619_4	290397.Adeh_1111	5.504e-131	441.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42Z45@68525|delta/epsilon subdivisions,2WTWB@28221|Deltaproteobacteria,2YW9J@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HAMP,HATPase_c,HisKA
TLS3_k127_5337619_2	1125863.JAFN01000001_gene307	7.4e-169	543.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2WJ2E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
TLS3_k127_5337619_12	404589.Anae109_1147	2.678e-62	233.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,42SJS@68525|delta/epsilon subdivisions,2WP7N@28221|Deltaproteobacteria,2YV9H@29|Myxococcales	28221|Deltaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
TLS3_k127_5337619_0	404589.Anae109_1146	0.0	1185.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2YUER@29|Myxococcales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
TLS3_k127_5337619_18	290397.Adeh_1106	1.007e-39	164.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
TLS3_k127_5337619_9	404589.Anae109_1144	3.35e-102	347.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,2YVB2@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
TLS3_k127_5337619_16	404589.Anae109_1143	2.279e-50	184.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,42U0Y@68525|delta/epsilon subdivisions,2WR00@28221|Deltaproteobacteria,2Z08B@29|Myxococcales	28221|Deltaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
TLS3_k127_5337619_15	404589.Anae109_1142	5.171e-51	183.0	COG1550@1|root,COG1550@2|Bacteria,1NBXZ@1224|Proteobacteria,42W9E@68525|delta/epsilon subdivisions,2WRK0@28221|Deltaproteobacteria,2YW04@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
TLS3_k127_5337619_1	243231.GSU1588	1.803e-204	661.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,43UH5@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
TLS3_k127_5373101_5	378806.STAUR_5810	1.003e-20	102.0	COG3148@1|root,COG3148@2|Bacteria,1QJQZ@1224|Proteobacteria,439DR@68525|delta/epsilon subdivisions,2X4NN@28221|Deltaproteobacteria,2YZB6@29|Myxococcales	28221|Deltaproteobacteria	S	DTW	-	-	-	-	-	-	-	-	-	-	-	-	DTW
TLS3_k127_5373101_2	404589.Anae109_2971	3.503e-136	448.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,42NHC@68525|delta/epsilon subdivisions,2WJQJ@28221|Deltaproteobacteria,2YUHD@29|Myxococcales	28221|Deltaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
TLS3_k127_5373101_4	404589.Anae109_2972	4.792e-32	141.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,42VRD@68525|delta/epsilon subdivisions,2WSCM@28221|Deltaproteobacteria,2Z2UB@29|Myxococcales	28221|Deltaproteobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
TLS3_k127_5373101_0	404589.Anae109_2973	4.488e-219	693.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,42NHS@68525|delta/epsilon subdivisions,2WJHI@28221|Deltaproteobacteria,2YU3U@29|Myxococcales	28221|Deltaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
TLS3_k127_5373101_1	404589.Anae109_4174	2.578e-181	606.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,43AQI@68525|delta/epsilon subdivisions,2X64F@28221|Deltaproteobacteria	1224|Proteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,PEGA,Pkinase,TPR_12
TLS3_k127_5373101_3	404589.Anae109_3046	1.438e-115	378.0	COG0840@1|root,COG3829@1|root,COG0840@2|Bacteria,COG3829@2|Bacteria,1MU9B@1224|Proteobacteria,42PCY@68525|delta/epsilon subdivisions,2WJCR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Chemotaxis sensory transducer	-	-	-	ko:K03406,ko:K13487	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Cache_3-Cache_2,HAMP,MCPsignal
TLS3_k127_5434876_5	404589.Anae109_3019	2.901e-25	121.0	COG0226@1|root,COG3638@1|root,COG0226@2|Bacteria,COG3638@2|Bacteria,1MVE9@1224|Proteobacteria,42USU@68525|delta/epsilon subdivisions,2WU8W@28221|Deltaproteobacteria,2Z19E@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran,LysR_substrate
TLS3_k127_5434876_2	404589.Anae109_3021	5.347e-149	476.0	COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,43AKJ@68525|delta/epsilon subdivisions,2WQ9Y@28221|Deltaproteobacteria,2YVPI@29|Myxococcales	28221|Deltaproteobacteria	P	Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
TLS3_k127_5434876_1	290397.Adeh_2372	9.397e-167	539.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,42NIG@68525|delta/epsilon subdivisions,2WIR1@28221|Deltaproteobacteria,2YUKH@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
TLS3_k127_5434876_4	404589.Anae109_1494	3.691e-50	192.0	COG1266@1|root,COG1266@2|Bacteria,1PPHW@1224|Proteobacteria,43E4M@68525|delta/epsilon subdivisions,2WZQ1@28221|Deltaproteobacteria,2Z2HR@29|Myxococcales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
TLS3_k127_5434876_0	404589.Anae109_1491	1.086e-206	657.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,42M7K@68525|delta/epsilon subdivisions,2WKKM@28221|Deltaproteobacteria,2YUWI@29|Myxococcales	28221|Deltaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
TLS3_k127_5434876_3	404589.Anae109_1490	3.479e-80	270.0	COG2896@1|root,COG2896@2|Bacteria,1MXMH@1224|Proteobacteria,42NTM@68525|delta/epsilon subdivisions,2WKIQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TLS3_k127_5463917_1	404589.Anae109_1339	7.919e-80	270.0	COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,42W6W@68525|delta/epsilon subdivisions,2X6V3@28221|Deltaproteobacteria,2YUYD@29|Myxococcales	28221|Deltaproteobacteria	I	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
TLS3_k127_5463917_0	290397.Adeh_2524	1.005e-242	760.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,42SZ0@68525|delta/epsilon subdivisions,2WPIR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
TLS3_k127_5463944_1	290397.Adeh_1643	8.989e-178	562.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2WJEI@28221|Deltaproteobacteria,2Z2X3@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
TLS3_k127_5463944_0	404589.Anae109_2168	5.319e-229	715.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2WJMS@28221|Deltaproteobacteria,2YWXC@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
TLS3_k127_5463944_5	215803.DB30_1205	4.722e-10	64.0	2B8AJ@1|root,321J6@2|Bacteria,1QAKI@1224|Proteobacteria,43E1Z@68525|delta/epsilon subdivisions,2WZGI@28221|Deltaproteobacteria,2Z23S@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5463944_4	404589.Anae109_2170	4.817e-49	180.0	COG2867@1|root,COG2867@2|Bacteria	2|Bacteria	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
TLS3_k127_5463944_2	290397.Adeh_1640	3.168e-173	547.0	COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,42M34@68525|delta/epsilon subdivisions,2WKJ6@28221|Deltaproteobacteria,2YX5K@29|Myxococcales	28221|Deltaproteobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
TLS3_k127_5463944_3	404589.Anae109_2172	1.948e-63	220.0	COG0824@1|root,COG0824@2|Bacteria,1PEBE@1224|Proteobacteria,42TIA@68525|delta/epsilon subdivisions,2WQ9X@28221|Deltaproteobacteria,2Z33F@29|Myxococcales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
TLS3_k127_5483748_3	1192034.CAP_2783	2.072e-44	177.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,42MNS@68525|delta/epsilon subdivisions,2WSQX@28221|Deltaproteobacteria,2YTZF@29|Myxococcales	28221|Deltaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
TLS3_k127_5483748_1	404589.Anae109_3016	3.4e-79	284.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,43BI9@68525|delta/epsilon subdivisions,2X6WN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
TLS3_k127_5483748_2	378806.STAUR_0961	1.569e-47	190.0	COG0491@1|root,COG0491@2|Bacteria,1NMU0@1224|Proteobacteria,432WR@68525|delta/epsilon subdivisions,2WY8W@28221|Deltaproteobacteria,2YX2P@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_5
TLS3_k127_5483748_0	290397.Adeh_3031	1.844e-112	382.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,42SYY@68525|delta/epsilon subdivisions,2WPKZ@28221|Deltaproteobacteria,2YXQP@29|Myxococcales	28221|Deltaproteobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
TLS3_k127_5511359_1	290397.Adeh_4017	1.383e-68	238.0	COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,42QX9@68525|delta/epsilon subdivisions,2WKS8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	PFAM Major facilitator superfamily	-	-	-	ko:K08224	-	-	-	-	ko00000,ko02000	2.A.1.36	-	-	MFS_1
TLS3_k127_5511359_3	404589.Anae109_0460	1.125e-38	154.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Gp58
TLS3_k127_5511359_0	404589.Anae109_2999	0.0	1614.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,42MZC@68525|delta/epsilon subdivisions,2WKRK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_10,Fer4_8
TLS3_k127_5511359_2	404589.Anae109_1106	9.926e-40	156.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,42P3J@68525|delta/epsilon subdivisions,2WKFS@28221|Deltaproteobacteria,2YWG4@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
TLS3_k127_5573575_12	290397.Adeh_2491	1.483e-50	185.0	COG1587@1|root,COG1587@2|Bacteria,1QYG8@1224|Proteobacteria,43CCC@68525|delta/epsilon subdivisions,2X7NB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Uroporphyrinogen-III synthase HemD	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
TLS3_k127_5573575_4	290397.Adeh_2492	1.313e-137	465.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria,2YUZ3@29|Myxococcales	28221|Deltaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
TLS3_k127_5573575_2	404589.Anae109_1374	2.3e-172	567.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,2YWEM@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
TLS3_k127_5573575_6	404589.Anae109_1373	6.928e-105	348.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,2Z3NJ@29|Myxococcales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
TLS3_k127_5573575_15	290397.Adeh_2495	2.047e-18	94.0	2A21P@1|root,30QBQ@2|Bacteria,1Q2MF@1224|Proteobacteria,43882@68525|delta/epsilon subdivisions,2X3HT@28221|Deltaproteobacteria,2YW5S@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5573575_13	404589.Anae109_1372	1.335e-45	168.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,2YVHU@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
TLS3_k127_5573575_3	404589.Anae109_1371	4.271e-154	495.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2WIP1@28221|Deltaproteobacteria,2YUT8@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the SEDS family	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
TLS3_k127_5573575_0	404589.Anae109_1370	2.411e-282	884.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2YU5Y@29|Myxococcales	28221|Deltaproteobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
TLS3_k127_5573575_7	290397.Adeh_2500	1.037e-101	342.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42UFT@68525|delta/epsilon subdivisions,2WR3P@28221|Deltaproteobacteria,2Z2Z3@29|Myxococcales	28221|Deltaproteobacteria	D	Involved in formation and maintenance of cell shape	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
TLS3_k127_5573575_5	404589.Anae109_1367	1.964e-118	400.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	peptidyl-prolyl isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
TLS3_k127_5573575_9	290397.Adeh_2502	3.279e-68	236.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2WP65@28221|Deltaproteobacteria,2YVJK@29|Myxococcales	28221|Deltaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
TLS3_k127_5573575_8	290397.Adeh_2503	7.831e-85	291.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria,2YZQW@29|Myxococcales	28221|Deltaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
TLS3_k127_5573575_10	290397.Adeh_2504	2.644e-66	236.0	COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2WS8K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
TLS3_k127_5573575_1	290397.Adeh_2505	2.623e-213	677.0	COG1572@1|root,COG1572@2|Bacteria,1N4MI@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
TLS3_k127_5623416_5	290397.Adeh_2732	2.014e-06	51.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PBS lyase	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
TLS3_k127_5623416_3	1242864.D187_004596	7.225e-101	339.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42QPJ@68525|delta/epsilon subdivisions,2WMNM@28221|Deltaproteobacteria,2YUW4@29|Myxococcales	28221|Deltaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR40H-1	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
TLS3_k127_5623416_2	290397.Adeh_2730	5.304e-102	356.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,43AKW@68525|delta/epsilon subdivisions,2X60Z@28221|Deltaproteobacteria,2Z385@29|Myxococcales	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
TLS3_k127_5623416_4	751945.Theos_0415	1.155e-15	90.0	COG3437@1|root,COG3437@2|Bacteria,1WI9N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
TLS3_k127_5623416_0	290397.Adeh_2728	3.328e-273	843.0	COG0017@1|root,COG0017@2|Bacteria,1MWFV@1224|Proteobacteria,42MJX@68525|delta/epsilon subdivisions,2WJDM@28221|Deltaproteobacteria,2YUKX@29|Myxococcales	28221|Deltaproteobacteria	J	asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
TLS3_k127_5623416_1	404589.Anae109_2719	4.625e-214	670.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
TLS3_k127_5628000_6	290397.Adeh_1564	5.937e-54	196.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2WQKR@28221|Deltaproteobacteria,2YVE5@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
TLS3_k127_5628000_0	404589.Anae109_2250	1.43e-322	1009.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42PVA@68525|delta/epsilon subdivisions,2WJ10@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB-1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
TLS3_k127_5628000_3	290397.Adeh_1566	6.166e-93	313.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1N3ZM@1224|Proteobacteria,42TUU@68525|delta/epsilon subdivisions,2WQ8Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KP	PFAM iron dependent repressor	ideR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,FeoA
TLS3_k127_5628000_1	290397.Adeh_1567	2.598e-129	431.0	COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,42RB0@68525|delta/epsilon subdivisions,2WN8G@28221|Deltaproteobacteria,2Z0N6@29|Myxococcales	28221|Deltaproteobacteria	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5628000_4	290397.Adeh_1568	1.96e-63	231.0	COG4659@1|root,COG4659@2|Bacteria,1N2GK@1224|Proteobacteria,42UH0@68525|delta/epsilon subdivisions,2WRRX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5628000_8	404589.Anae109_2244	9.346e-38	151.0	2CKY4@1|root,328RE@2|Bacteria,1N9BF@1224|Proteobacteria,42WSY@68525|delta/epsilon subdivisions,2WTE6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5628000_2	404589.Anae109_2243	2.918e-101	342.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria,2YV2N@29|Myxococcales	28221|Deltaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE,MFS_1
TLS3_k127_5628000_5	290397.Adeh_0191	6.223e-60	220.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,42SK2@68525|delta/epsilon subdivisions,2WPB3@28221|Deltaproteobacteria,2Z0CU@29|Myxococcales	28221|Deltaproteobacteria	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	bfr	GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
TLS3_k127_5628701_7	404589.Anae109_0813	2.375e-57	221.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,43DRN@68525|delta/epsilon subdivisions,2WYQA@28221|Deltaproteobacteria,2Z0CV@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
TLS3_k127_5628701_0	404589.Anae109_0812	9.48e-238	740.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42PGQ@68525|delta/epsilon subdivisions,2WMJB@28221|Deltaproteobacteria,2YUUP@29|Myxococcales	28221|Deltaproteobacteria	C	Cysteine-rich domain	glpC	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_17,Fer4_8
TLS3_k127_5628701_5	404589.Anae109_0811	4.509e-76	256.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42N9V@68525|delta/epsilon subdivisions,2WJWQ@28221|Deltaproteobacteria,2YV2V@29|Myxococcales	28221|Deltaproteobacteria	C	Rubrerythrin	rbr	GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
TLS3_k127_5628701_8	903818.KI912268_gene3050	4.471e-24	112.0	COG0735@1|root,COG0735@2|Bacteria,3Y7UH@57723|Acidobacteria	57723|Acidobacteria	P	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
TLS3_k127_5628701_4	1380390.JIAT01000001_gene5116	1.251e-79	277.0	COG2267@1|root,COG2267@2|Bacteria,2I2IM@201174|Actinobacteria,4CQH4@84995|Rubrobacteria	84995|Rubrobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_5628701_3	518766.Rmar_0040	1.286e-86	308.0	COG2126@1|root,COG2126@2|Bacteria,4NEX1@976|Bacteroidetes	976|Bacteroidetes	J	Pfam Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
TLS3_k127_5628701_6	404589.Anae109_1609	2.481e-60	226.0	COG0116@1|root,COG0116@2|Bacteria	2|Bacteria	L	23S rRNA (guanine(2445)-N(2))-methyltransferase activity	-	-	2.1.1.209	ko:K21515	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_31,UPF0020
TLS3_k127_5628701_2	290397.Adeh_0181	2.357e-116	383.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,42UB0@68525|delta/epsilon subdivisions,2X5NB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
TLS3_k127_5628701_1	1370125.AUWT01000035_gene1426	2.459e-127	413.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,233NH@1762|Mycobacteriaceae	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
TLS3_k127_5630500_4	391625.PPSIR1_25966	2.125e-30	130.0	COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,42UHJ@68525|delta/epsilon subdivisions,2WT4S@28221|Deltaproteobacteria,2YUXZ@29|Myxococcales	28221|Deltaproteobacteria	K	Arabinose-binding domain of AraC transcription regulator, N-term	oruR2	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
TLS3_k127_5630500_0	1122176.KB903544_gene798	5.039e-83	295.0	COG0815@1|root,COG0815@2|Bacteria,4NMJK@976|Bacteroidetes,1IZV9@117747|Sphingobacteriia	976|Bacteroidetes	M	Carbon-nitrogen hydrolase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
TLS3_k127_5630500_2	290397.Adeh_3297	6.283e-49	189.0	COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,43095@68525|delta/epsilon subdivisions,2WVAH@28221|Deltaproteobacteria,2YVKH@29|Myxococcales	28221|Deltaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
TLS3_k127_5630500_3	522306.CAP2UW1_0011	2.064e-35	153.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
TLS3_k127_5630500_1	215803.DB30_6072	2.653e-54	201.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1QV0D@1224|Proteobacteria,438B0@68525|delta/epsilon subdivisions,2X3KB@28221|Deltaproteobacteria,2YWEE@29|Myxococcales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_4,RsbRD_N
TLS3_k127_5644575_3	404589.Anae109_2599	1.025e-85	287.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2YTUI@29|Myxococcales	28221|Deltaproteobacteria	P	copper-translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
TLS3_k127_5644575_4	404589.Anae109_2601	1.037e-71	255.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,42SVS@68525|delta/epsilon subdivisions,2WNMI@28221|Deltaproteobacteria,2YZY7@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
TLS3_k127_5644575_1	404589.Anae109_1215	4.849e-109	361.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	JD73_00815	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
TLS3_k127_5644575_7	1128421.JAGA01000004_gene2582	7.519e-13	73.0	COG0745@1|root,COG0745@2|Bacteria	1128421.JAGA01000004_gene2582|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5644575_6	266117.Rxyl_0783	7.69e-22	100.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CPX6@84995|Rubrobacteria	84995|Rubrobacteria	K	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms Transcription	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_5644575_0	404589.Anae109_3352	7.718e-319	981.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,42QW3@68525|delta/epsilon subdivisions,2WNT9@28221|Deltaproteobacteria,2YWWY@29|Myxococcales	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_5644575_2	404589.Anae109_3351	8.337e-89	301.0	COG0639@1|root,COG0639@2|Bacteria,1MUV1@1224|Proteobacteria,42RNB@68525|delta/epsilon subdivisions,2WNEW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
TLS3_k127_5644575_5	290397.Adeh_3699	2.461e-31	128.0	COG0515@1|root,COG0589@1|root,COG0515@2|Bacteria,COG0589@2|Bacteria,1MV1P@1224|Proteobacteria,42VSC@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Protein tyrosine kinase	MA20_09295	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Usp
TLS3_k127_5704163_1	1306174.JODP01000001_gene5230	5.165e-100	351.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria	201174|Actinobacteria	E	decarboxylase	ddc	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
TLS3_k127_5704163_3	404589.Anae109_1354	1.893e-66	229.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,42TJ5@68525|delta/epsilon subdivisions,2WQ2Z@28221|Deltaproteobacteria,2Z24M@29|Myxococcales	28221|Deltaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
TLS3_k127_5704163_6	404589.Anae109_1353	7.888e-34	138.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Rubrerythrin
TLS3_k127_5704163_5	404589.Anae109_1352	1.945e-39	167.0	COG2259@1|root,COG2259@2|Bacteria,1RIFW@1224|Proteobacteria,42SRS@68525|delta/epsilon subdivisions,2WPBA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM DoxX family protein	-	-	-	-	-	-	-	-	-	-	-	-	MauE
TLS3_k127_5704163_4	290397.Adeh_2516	1.86e-59	213.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42NTP@68525|delta/epsilon subdivisions,2WQME@28221|Deltaproteobacteria,2YVSW@29|Myxococcales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	tenI	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
TLS3_k127_5704163_0	290397.Adeh_2518	5.369e-139	445.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,2YUEF@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
TLS3_k127_5733891_3	290397.Adeh_2911	1.385e-88	302.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,1MVYT@1224|Proteobacteria,42S95@68525|delta/epsilon subdivisions,2WNPS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	ErfK YbiS YcfS YnhG family protein	-	-	-	ko:K16291	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	LysM,YkuD
TLS3_k127_5733891_0	290397.Adeh_2085	1.64e-219	685.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NQ1@68525|delta/epsilon subdivisions,2X5KW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
TLS3_k127_5733891_1	395493.BegalDRAFT_1234	5.597e-130	426.0	COG2899@1|root,COG2899@2|Bacteria,1NURT@1224|Proteobacteria,1RQ9S@1236|Gammaproteobacteria,460FU@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF475)	-	-	-	ko:K09799	-	-	-	-	ko00000	-	-	-	DUF475
TLS3_k127_5733891_2	861299.J421_1907	3.153e-126	412.0	COG2084@1|root,COG2084@2|Bacteria,1ZTZC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
TLS3_k127_5733891_4	404589.Anae109_2927	2.024e-65	229.0	COG1075@1|root,COG1075@2|Bacteria,1QTCH@1224|Proteobacteria,437VW@68525|delta/epsilon subdivisions,2WYPR@28221|Deltaproteobacteria,2YUCF@29|Myxococcales	28221|Deltaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_574828_2	404589.Anae109_1602	5.208e-44	162.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42MPR@68525|delta/epsilon subdivisions,2WNM3@28221|Deltaproteobacteria,2Z06N@29|Myxococcales	28221|Deltaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
TLS3_k127_574828_3	290397.Adeh_3461	1.009e-20	98.0	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	comEA	-	2.4.1.21	ko:K00703,ko:K02237,ko:K02238	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00429,M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko02044	3.A.11.1,3.A.11.2	GT5	-	HHH_3,PLDc_2,SLBB
TLS3_k127_574828_0	404589.Anae109_4174	4.233e-96	336.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,43AQI@68525|delta/epsilon subdivisions,2X64F@28221|Deltaproteobacteria	1224|Proteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,PEGA,Pkinase,TPR_12
TLS3_k127_574828_1	1278073.MYSTI_07598	2.171e-51	209.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	asgD	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
TLS3_k127_5755093_5	290397.Adeh_3917	1.469e-144	460.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YUAB@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_5755093_7	290397.Adeh_3133	2.012e-120	409.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,42MQV@68525|delta/epsilon subdivisions,2WIZC@28221|Deltaproteobacteria,2YWY9@29|Myxococcales	28221|Deltaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
TLS3_k127_5755093_10	290397.Adeh_1448	1.397e-30	133.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_5755093_6	404589.Anae109_1597	3.359e-122	429.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X7MY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
TLS3_k127_5755093_2	404589.Anae109_3492	1.644e-249	779.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria	1224|Proteobacteria	Q	COG1233 Phytoene dehydrogenase and related proteins	MA20_01895	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
TLS3_k127_5755093_3	290397.Adeh_0820	3.041e-204	643.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42PMA@68525|delta/epsilon subdivisions,2X5AR@28221|Deltaproteobacteria,2Z0NV@29|Myxococcales	28221|Deltaproteobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
TLS3_k127_5755093_0	404589.Anae109_1024	0.0	1560.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
TLS3_k127_5755093_4	404589.Anae109_1023	2.91e-156	501.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,42N4G@68525|delta/epsilon subdivisions,2WJ8A@28221|Deltaproteobacteria,2Z15D@29|Myxococcales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
TLS3_k127_5755093_9	404589.Anae109_3719	1.281e-34	137.0	COG2050@1|root,COG2050@2|Bacteria,1RH35@1224|Proteobacteria,42U19@68525|delta/epsilon subdivisions,2WR05@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM thioesterase superfamily	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
TLS3_k127_5755093_1	404589.Anae109_0036	2.363e-256	800.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,42N9T@68525|delta/epsilon subdivisions,2WIMI@28221|Deltaproteobacteria,2Z24K@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
TLS3_k127_5755093_8	404589.Anae109_0037	5.956e-103	369.0	2E98K@1|root,333GZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5762224_4	404589.Anae109_1984	8.286e-64	222.0	COG0392@1|root,COG0392@2|Bacteria,1PPSZ@1224|Proteobacteria,434R6@68525|delta/epsilon subdivisions,2WZ2B@28221|Deltaproteobacteria,2Z16A@29|Myxococcales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
TLS3_k127_5762224_6	1239962.C943_03437	4.112e-15	77.0	COG0604@1|root,COG0604@2|Bacteria,4NHHT@976|Bacteroidetes,47N64@768503|Cytophagia	976|Bacteroidetes	C	COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_2,ADH_zinc_N_2
TLS3_k127_5762224_7	1121875.KB907549_gene1915	5.972e-13	70.0	COG0604@1|root,COG0604@2|Bacteria,4NHHT@976|Bacteroidetes,1HYRT@117743|Flavobacteriia	976|Bacteroidetes	C	COG0604 NADPH quinone reductase and related Zn-dependent	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_2,ADH_zinc_N_2
TLS3_k127_5762224_0	404589.Anae109_4063	1.02e-224	726.0	COG1541@1|root,COG1541@2|Bacteria,1R8T9@1224|Proteobacteria,433V4@68525|delta/epsilon subdivisions,2X3KT@28221|Deltaproteobacteria,2YWG6@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
TLS3_k127_5762224_2	404589.Anae109_2914	1.011e-104	357.0	COG2133@1|root,COG2133@2|Bacteria,1PEHH@1224|Proteobacteria,437W5@68525|delta/epsilon subdivisions,2X35P@28221|Deltaproteobacteria,2YUDG@29|Myxococcales	28221|Deltaproteobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5762224_3	404589.Anae109_2915	5.351e-70	248.0	COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,43AHK@68525|delta/epsilon subdivisions,2X5XT@28221|Deltaproteobacteria,2YVZ8@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5762224_1	404589.Anae109_3049	2.153e-109	373.0	COG0484@1|root,COG0484@2|Bacteria,1QYGD@1224|Proteobacteria,43CCI@68525|delta/epsilon subdivisions,2X7NG@28221|Deltaproteobacteria,2Z1CZ@29|Myxococcales	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	GSu_C4xC__C2xCH
TLS3_k127_5765126_3	290397.Adeh_0378	6.432e-104	341.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria,2YVA6@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
TLS3_k127_5765126_5	861299.J421_0447	4.829e-89	302.0	COG2107@1|root,COG2107@2|Bacteria,1ZTVU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
TLS3_k127_5765126_0	290397.Adeh_0375	1.179e-265	826.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2WJMB@28221|Deltaproteobacteria,2Z05N@29|Myxococcales	28221|Deltaproteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
TLS3_k127_5765126_4	404589.Anae109_4204	8.9e-98	342.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2WNJ6@28221|Deltaproteobacteria,2YU8C@29|Myxococcales	28221|Deltaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
TLS3_k127_5765126_6	404589.Anae109_4205	2.9e-86	301.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,42QXP@68525|delta/epsilon subdivisions,2WP9I@28221|Deltaproteobacteria,2Z0YH@29|Myxococcales	28221|Deltaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3392	Flavoprotein
TLS3_k127_5765126_2	404589.Anae109_4206	6.439e-200	643.0	COG1060@1|root,COG1060@2|Bacteria,1QN23@1224|Proteobacteria,42M6Z@68525|delta/epsilon subdivisions,2WJ4C@28221|Deltaproteobacteria,2YYN9@29|Myxococcales	28221|Deltaproteobacteria	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	1.21.98.1,2.5.1.120,2.5.1.77	ko:K11779,ko:K11784,ko:K18285	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396,R10667	RC00021,RC01381,RC02329,RC03002,RC03007,RC03234	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3391	Radical_SAM
TLS3_k127_5765126_1	404589.Anae109_4207	1.627e-237	741.0	COG1060@1|root,COG1427@1|root,COG1060@2|Bacteria,COG1427@2|Bacteria,1MX50@1224|Proteobacteria,42M6U@68525|delta/epsilon subdivisions,2WJ6Y@28221|Deltaproteobacteria,2YZ18@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
TLS3_k127_5788709_3	292459.STH972	2.116e-13	70.0	COG2043@1|root,COG2043@2|Bacteria,1TT5P@1239|Firmicutes	1239|Firmicutes	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
TLS3_k127_5788709_0	1242864.D187_000546	4.886e-177	572.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,42MAA@68525|delta/epsilon subdivisions,2WJZC@28221|Deltaproteobacteria,2YUE7@29|Myxococcales	28221|Deltaproteobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
TLS3_k127_5788709_1	290397.Adeh_1016	4.02e-62	230.0	COG0438@1|root,COG5653@1|root,COG0438@2|Bacteria,COG5653@2|Bacteria,1MWSZ@1224|Proteobacteria,4309V@68525|delta/epsilon subdivisions,2WVBY@28221|Deltaproteobacteria,2YZHG@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_5788709_2	404589.Anae109_0559	6.285e-21	93.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
TLS3_k127_5821104_12	290397.Adeh_1258	2.994e-78	273.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2WIW9@28221|Deltaproteobacteria,2YUTG@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2475	Mur_ligase_C,Mur_ligase_M
TLS3_k127_5821104_7	290397.Adeh_1257	9.789e-141	451.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2WK95@28221|Deltaproteobacteria,2YU1S@29|Myxococcales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
TLS3_k127_5821104_10	215803.DB30_6643	1.283e-88	309.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,42SHU@68525|delta/epsilon subdivisions,2WPGG@28221|Deltaproteobacteria,2YWV3@29|Myxococcales	28221|Deltaproteobacteria	S	cAMP phosphodiesterases class-II	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2,PDEase_II
TLS3_k127_5821104_13	290397.Adeh_1256	1.055e-64	231.0	COG0664@1|root,COG0664@2|Bacteria,1NHNS@1224|Proteobacteria,42X3Y@68525|delta/epsilon subdivisions,2WT4M@28221|Deltaproteobacteria,2YVRK@29|Myxococcales	28221|Deltaproteobacteria	K	cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	cNMP_binding
TLS3_k127_5821104_2	404589.Anae109_2512	1.34e-187	590.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2WIXY@28221|Deltaproteobacteria,2YTTG@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844	AIRS,AIRS_C
TLS3_k127_5821104_11	404589.Anae109_2513	3.276e-88	314.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2WJT0@28221|Deltaproteobacteria,2YVC1@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
TLS3_k127_5821104_6	290397.Adeh_1253	2.496e-144	476.0	COG1233@1|root,COG1233@2|Bacteria,1Q2HN@1224|Proteobacteria,4384H@68525|delta/epsilon subdivisions,2X3EF@28221|Deltaproteobacteria,2YVQ0@29|Myxococcales	28221|Deltaproteobacteria	Q	COG1233 Phytoene dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
TLS3_k127_5821104_17	404589.Anae109_2515	1.061e-28	133.0	COG0227@1|root,COG0227@2|Bacteria,1PTFN@1224|Proteobacteria,42V1S@68525|delta/epsilon subdivisions,2WR85@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
TLS3_k127_5821104_5	290397.Adeh_1251	2.217e-167	544.0	2A7N3@1|root,30WK3@2|Bacteria,1NERD@1224|Proteobacteria,42P7M@68525|delta/epsilon subdivisions,2WJTH@28221|Deltaproteobacteria,2Z0ZJ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5821104_4	290397.Adeh_1249	3.083e-181	570.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria	1224|Proteobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iSFV_1184.SFV_1640,iSF_1195.SF1648,iSFxv_1172.SFxv_1849,iS_1188.S1780	A_deaminase
TLS3_k127_5821104_8	269799.Gmet_1162	6.91e-112	370.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria,43TKY@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1162	THF_DHG_CYH,THF_DHG_CYH_C
TLS3_k127_5821104_9	290397.Adeh_1246	3.955e-95	336.0	COG1409@1|root,COG1409@2|Bacteria,1PCIF@1224|Proteobacteria,438G6@68525|delta/epsilon subdivisions,2X3R2@28221|Deltaproteobacteria,2YWW5@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
TLS3_k127_5821104_3	404589.Anae109_2522	5.572e-185	583.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,42QM6@68525|delta/epsilon subdivisions,2WK2P@28221|Deltaproteobacteria,2YU3I@29|Myxococcales	28221|Deltaproteobacteria	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
TLS3_k127_5821104_14	290397.Adeh_1244	6.872e-54	216.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,42RS9@68525|delta/epsilon subdivisions,2WP93@28221|Deltaproteobacteria,2Z1I1@29|Myxococcales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
TLS3_k127_5821104_1	404589.Anae109_2524	8.71e-209	668.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,42MQ1@68525|delta/epsilon subdivisions,2WJII@28221|Deltaproteobacteria,2YYEJ@29|Myxococcales	28221|Deltaproteobacteria	F	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
TLS3_k127_5821104_0	404589.Anae109_2525	2.381e-259	832.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,42MR9@68525|delta/epsilon subdivisions,2WIP3@28221|Deltaproteobacteria,2YUNJ@29|Myxococcales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
TLS3_k127_5821104_16	1297742.A176_04467	2.345e-36	147.0	COG0810@1|root,COG0810@2|Bacteria,1NG3C@1224|Proteobacteria,42V3M@68525|delta/epsilon subdivisions,2WS05@28221|Deltaproteobacteria,2YZ7E@29|Myxococcales	28221|Deltaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
TLS3_k127_5848585_2	404589.Anae109_3389	6.384e-78	267.0	COG5373@1|root,COG5373@2|Bacteria,1QX7Q@1224|Proteobacteria,43C0Q@68525|delta/epsilon subdivisions,2X7BB@28221|Deltaproteobacteria,2Z3F0@29|Myxococcales	28221|Deltaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5848585_3	404589.Anae109_3388	7.147e-57	216.0	2BQ3I@1|root,32IXY@2|Bacteria,1PC2U@1224|Proteobacteria,435BB@68525|delta/epsilon subdivisions,2X97P@28221|Deltaproteobacteria,2Z2FH@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5848585_1	290397.Adeh_3323	8.62e-150	509.0	COG1729@1|root,COG1729@2|Bacteria,1QX7P@1224|Proteobacteria,43C0P@68525|delta/epsilon subdivisions,2X7BA@28221|Deltaproteobacteria,2YUW6@29|Myxococcales	28221|Deltaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5848585_0	290397.Adeh_3322	6.905e-297	971.0	COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,1MX82@1224|Proteobacteria,42TQ9@68525|delta/epsilon subdivisions,2WR3B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
TLS3_k127_5848585_4	404589.Anae109_3383	2.774e-42	165.0	COG1716@1|root,COG1716@2|Bacteria,1NEW5@1224|Proteobacteria,42VUF@68525|delta/epsilon subdivisions,2WRV9@28221|Deltaproteobacteria,2YV34@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,TonB_C,Yop-YscD_cpl
TLS3_k127_5856739_0	290397.Adeh_3796	4.094e-216	683.0	COG0793@1|root,COG1361@1|root,COG0793@2|Bacteria,COG1361@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WTUX@28221|Deltaproteobacteria,2YTTM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
TLS3_k127_5856739_1	290397.Adeh_3793	2.877e-209	659.0	COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,42QDI@68525|delta/epsilon subdivisions,2WJMG@28221|Deltaproteobacteria,2YWDT@29|Myxococcales	28221|Deltaproteobacteria	H	glutamate--cysteine ligase	-	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
TLS3_k127_5856739_2	378806.STAUR_6339	2.9e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,1PYTB@1224|Proteobacteria,42VYS@68525|delta/epsilon subdivisions,2XA0E@28221|Deltaproteobacteria,2YW26@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
TLS3_k127_586121_8	290397.Adeh_3568	2.496e-90	314.0	COG0461@1|root,COG0461@2|Bacteria,1PI8N@1224|Proteobacteria,42QSR@68525|delta/epsilon subdivisions,2WPAX@28221|Deltaproteobacteria,2Z2Z0@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
TLS3_k127_586121_10	290397.Adeh_3569	5.114e-76	262.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
TLS3_k127_586121_13	290397.Adeh_3570	1.419e-56	202.0	COG1664@1|root,COG1664@2|Bacteria,1QAFI@1224|Proteobacteria,4351U@68525|delta/epsilon subdivisions,2WZCU@28221|Deltaproteobacteria,2Z1UZ@29|Myxococcales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
TLS3_k127_586121_17	404589.Anae109_3692	4.485e-42	158.0	COG1664@1|root,COG1664@2|Bacteria,1RHS7@1224|Proteobacteria	1224|Proteobacteria	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
TLS3_k127_586121_4	404589.Anae109_3693	2.163e-114	376.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,42T8M@68525|delta/epsilon subdivisions,2WPBS@28221|Deltaproteobacteria,2Z198@29|Myxococcales	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	agmH	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
TLS3_k127_586121_15	404589.Anae109_3694	1.33e-53	205.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
TLS3_k127_586121_12	290397.Adeh_3574	3.059e-73	252.0	COG0745@1|root,COG0745@2|Bacteria	290397.Adeh_3574|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_586121_3	290397.Adeh_3575	1.322e-132	428.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,42T24@68525|delta/epsilon subdivisions,2WPF8@28221|Deltaproteobacteria,2YV09@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
TLS3_k127_586121_7	404589.Anae109_3699	6.518e-102	347.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2Z0M6@29|Myxococcales	28221|Deltaproteobacteria	C	Semialdehyde dehydrogenase, NAD binding domain	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
TLS3_k127_586121_1	290397.Adeh_0382	4.963e-196	626.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2YXED@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
TLS3_k127_586121_11	290397.Adeh_3581	7.369e-74	263.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,42RIT@68525|delta/epsilon subdivisions,2WP64@28221|Deltaproteobacteria,2Z1V2@29|Myxococcales	28221|Deltaproteobacteria	O	Glycoprotease family	yeaZ	-	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
TLS3_k127_586121_0	404589.Anae109_3703	9.934e-231	735.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2YTYT@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
TLS3_k127_586121_2	290397.Adeh_3583	1.252e-164	528.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2WK14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
TLS3_k127_586121_9	404589.Anae109_3705	3e-90	310.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,42U86@68525|delta/epsilon subdivisions,2WX3A@28221|Deltaproteobacteria,2Z1AX@29|Myxococcales	28221|Deltaproteobacteria	M	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
TLS3_k127_586121_6	290397.Adeh_3585	1.664e-103	347.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,42PTV@68525|delta/epsilon subdivisions,2WMWK@28221|Deltaproteobacteria,2YUTJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
TLS3_k127_586121_5	290397.Adeh_3586	1.287e-106	356.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TLS3_k127_5872890_4	404589.Anae109_2711	1.019e-09	72.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,42TCJ@68525|delta/epsilon subdivisions,2X5PW@28221|Deltaproteobacteria,2Z2ZQ@29|Myxococcales	28221|Deltaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
TLS3_k127_5872890_0	290397.Adeh_2720	2.064e-244	782.0	COG1480@1|root,COG1480@2|Bacteria,1NCY5@1224|Proteobacteria,42MI9@68525|delta/epsilon subdivisions,2WJI1@28221|Deltaproteobacteria,2YUW7@29|Myxococcales	28221|Deltaproteobacteria	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
TLS3_k127_5872890_1	290397.Adeh_2721	1.038e-177	576.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,42N58@68525|delta/epsilon subdivisions,2WIQS@28221|Deltaproteobacteria,2YTWI@29|Myxococcales	28221|Deltaproteobacteria	T	PhoH-like protein	phoH2	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
TLS3_k127_5872890_3	290397.Adeh_2722	1.609e-134	437.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
TLS3_k127_5872890_2	290397.Adeh_2723	5.405e-165	541.0	COG0457@1|root,COG0457@2|Bacteria	290397.Adeh_2723|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_597105_0	404589.Anae109_0699	1.843e-215	691.0	COG4775@1|root,COG4775@2|Bacteria,1RJPJ@1224|Proteobacteria,42TA2@68525|delta/epsilon subdivisions,2WP1H@28221|Deltaproteobacteria,2YZDW@29|Myxococcales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
TLS3_k127_597105_7	290397.Adeh_0657	6.851e-64	226.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
TLS3_k127_597105_2	290397.Adeh_0658	3.375e-111	381.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WQJT@28221|Deltaproteobacteria,2YV3J@29|Myxococcales	28221|Deltaproteobacteria	FP	Ppx GppA	gppA-1	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
TLS3_k127_597105_1	290397.Adeh_0659	3.221e-147	477.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YVNE@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
TLS3_k127_597105_8	404589.Anae109_0704	2.656e-48	188.0	COG0810@1|root,COG0810@2|Bacteria,1Q9SX@1224|Proteobacteria,42UPJ@68525|delta/epsilon subdivisions,2WQZ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TonB C terminal	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	TonB_2
TLS3_k127_597105_9	290397.Adeh_0661	1.429e-47	187.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2WQD4@28221|Deltaproteobacteria,2YVFC@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
TLS3_k127_597105_4	404589.Anae109_0706	6.252e-103	349.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,42PKF@68525|delta/epsilon subdivisions,2WNQ4@28221|Deltaproteobacteria,2Z08C@29|Myxococcales	28221|Deltaproteobacteria	U	MotA TolQ ExbB proton channel	aglX	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
TLS3_k127_597105_3	290397.Adeh_0664	4.11e-110	361.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,2YY1K@29|Myxococcales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
TLS3_k127_597105_10	1144275.COCOR_06242	1.45e-34	146.0	2E2XW@1|root,32XYS@2|Bacteria,1N3ID@1224|Proteobacteria,42UFM@68525|delta/epsilon subdivisions,2WQKF@28221|Deltaproteobacteria,2YVPU@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_597105_5	290397.Adeh_0666	1.448e-96	320.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,42MAM@68525|delta/epsilon subdivisions,2WK4Y@28221|Deltaproteobacteria,2YV0E@29|Myxococcales	28221|Deltaproteobacteria	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
TLS3_k127_597105_6	404589.Anae109_0711	8.281e-74	268.0	COG2177@1|root,COG2177@2|Bacteria,1R85B@1224|Proteobacteria,42PXG@68525|delta/epsilon subdivisions,2WKX3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
TLS3_k127_6012078_4	404589.Anae109_2477	2.216e-145	462.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MB6@68525|delta/epsilon subdivisions,2WJMI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	ato-2	-	2.8.3.18,3.1.2.1	ko:K01067,ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00227,R10343	RC00004,RC00012,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1125	AcetylCoA_hyd_C,AcetylCoA_hydro
TLS3_k127_6012078_5	290397.Adeh_1287	3.589e-112	381.0	COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,4307A@68525|delta/epsilon subdivisions,2WV7X@28221|Deltaproteobacteria,2YVIM@29|Myxococcales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
TLS3_k127_6012078_6	290397.Adeh_1286	2.369e-66	239.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,43EF3@68525|delta/epsilon subdivisions,2X0ID@28221|Deltaproteobacteria,2Z1N2@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_6012078_7	290397.Adeh_2798	5.417e-50	186.0	COG0346@1|root,COG0346@2|Bacteria,1RH4C@1224|Proteobacteria,431XP@68525|delta/epsilon subdivisions,2WWM1@28221|Deltaproteobacteria,2Z0KY@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_6012078_8	290397.Adeh_2924	1.988e-37	146.0	2E6EV@1|root,3312A@2|Bacteria,1N8Q0@1224|Proteobacteria,42WW1@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PgaD-like protein	-	-	-	ko:K11937	ko02026,map02026	-	-	-	ko00000,ko00001	-	-	-	PgaD
TLS3_k127_6012078_2	290397.Adeh_2925	2.079e-215	674.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,42Q7W@68525|delta/epsilon subdivisions,2WKZ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.212	ko:K00752,ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.10,4.D.1.1.2,4.D.1.1.3,4.D.1.1.4,4.D.1.1.5	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_6012078_0	290397.Adeh_2926	9.435e-312	967.0	COG0726@1|root,COG1649@1|root,COG0726@2|Bacteria,COG1649@2|Bacteria,1MWR2@1224|Proteobacteria,43AG1@68525|delta/epsilon subdivisions,2WPD3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	-	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	Polysacc_deac_1
TLS3_k127_6012078_1	290397.Adeh_1285	9.854e-219	709.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,42MBU@68525|delta/epsilon subdivisions,2WIJP@28221|Deltaproteobacteria,2YWW6@29|Myxococcales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
TLS3_k127_6012078_3	443144.GM21_3357	1.066e-165	535.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pulE-3	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
TLS3_k127_6016417_0	404589.Anae109_0433	1.673e-254	791.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WJ41@28221|Deltaproteobacteria,2YUJJ@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter, ATP-binding protein	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_6016417_10	404589.Anae109_0431	1.312e-85	315.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
TLS3_k127_6016417_8	1538644.KO02_19665	1.455e-89	312.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,1IQP5@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_6016417_6	290397.Adeh_3996	2.147e-106	358.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria	1224|Proteobacteria	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
TLS3_k127_6016417_4	404589.Anae109_0429	3.354e-125	413.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,42QRU@68525|delta/epsilon subdivisions,2WMNQ@28221|Deltaproteobacteria,2Z15R@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
TLS3_k127_6016417_9	1242864.D187_004502	1.234e-85	290.0	COG0600@1|root,COG0600@2|Bacteria,1PC26@1224|Proteobacteria,4303X@68525|delta/epsilon subdivisions,2WVHT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
TLS3_k127_6016417_5	404589.Anae109_0427	1.297e-123	407.0	COG0715@1|root,COG0715@2|Bacteria,1RHDX@1224|Proteobacteria,42V6G@68525|delta/epsilon subdivisions,2WRZJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	iAF987.Gmet_0996	NMT1_2
TLS3_k127_6016417_11	404589.Anae109_0425	7.27e-60	213.0	COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,42W41@68525|delta/epsilon subdivisions,2WSGZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
TLS3_k127_6016417_7	290397.Adeh_4002	1.145e-101	335.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WN1U@28221|Deltaproteobacteria,2Z2Z8@29|Myxococcales	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
TLS3_k127_6016417_3	404589.Anae109_0421	3.797e-129	417.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2WJEX@28221|Deltaproteobacteria,2YUBB@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
TLS3_k127_6016417_1	290397.Adeh_4004	3.402e-141	471.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2YVAR@29|Myxococcales	28221|Deltaproteobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
TLS3_k127_6016417_2	290397.Adeh_4005	5.22e-140	455.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2YV6J@29|Myxococcales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
TLS3_k127_6016417_12	404589.Anae109_0418	9.715e-19	85.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria,2YVQ5@29|Myxococcales	28221|Deltaproteobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
TLS3_k127_6035201_3	290397.Adeh_1055	3.752e-101	331.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2YTZW@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_6035201_0	290397.Adeh_1054	0.0	1350.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria,2YU71@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
TLS3_k127_6035201_1	1254432.SCE1572_10845	9.284e-234	740.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria,2YXPN@29|Myxococcales	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
TLS3_k127_6035201_2	404589.Anae109_1103	1.496e-201	638.0	COG1752@1|root,COG1752@2|Bacteria,1R76S@1224|Proteobacteria	1224|Proteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
TLS3_k127_6035201_4	404589.Anae109_1102	1.341e-53	190.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2YV73@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_6043403_6	290397.Adeh_2903	1.899e-75	259.0	COG3005@1|root,COG3005@2|Bacteria,1N0I4@1224|Proteobacteria,42R1B@68525|delta/epsilon subdivisions,2WSF5@28221|Deltaproteobacteria,2Z0Q9@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c nitrite reductase	-	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
TLS3_k127_6043403_0	290397.Adeh_2902	2.17e-304	941.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,42MPU@68525|delta/epsilon subdivisions,2WIJ1@28221|Deltaproteobacteria,2YUSH@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
TLS3_k127_6043403_7	290397.Adeh_2198	1.052e-56	202.0	COG0517@1|root,COG0517@2|Bacteria,1NACJ@1224|Proteobacteria	1224|Proteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
TLS3_k127_6043403_1	404589.Anae109_1595	7.212e-147	470.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	yeiE	GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS3_k127_6043403_2	903814.ELI_0702	1.408e-131	430.0	COG0031@1|root,COG0031@2|Bacteria,1TRM4@1239|Firmicutes,25BF7@186801|Clostridia,25Y3Y@186806|Eubacteriaceae	186801|Clostridia	H	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_6043403_10	1144275.COCOR_01503	3.59e-25	115.0	COG4281@1|root,COG4281@2|Bacteria	2|Bacteria	I	acyl-coa-binding protein	dbi	-	-	-	-	-	-	-	-	-	-	-	ACBP
TLS3_k127_6043403_3	1122927.KB895414_gene5126	1.157e-115	397.0	COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,26QXS@186822|Paenibacillaceae	91061|Bacilli	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
TLS3_k127_6043403_8	1122604.JONR01000025_gene4593	5.846e-53	198.0	COG4757@1|root,COG4757@2|Bacteria,1Q1V6@1224|Proteobacteria,1RT3H@1236|Gammaproteobacteria,1X7TF@135614|Xanthomonadales	135614|Xanthomonadales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
TLS3_k127_6043403_11	106370.Francci3_1355	0.0001661	52.0	COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,4ET2V@85013|Frankiales	201174|Actinobacteria	Q	PFAM isochorismatase hydrolase	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
TLS3_k127_6043403_4	1279019.ARQK01000048_gene135	1.356e-107	367.0	COG1680@1|root,COG1680@2|Bacteria,1PGVY@1224|Proteobacteria,1SWR8@1236|Gammaproteobacteria,1X1X6@135613|Chromatiales	135613|Chromatiales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Beta-lactamase
TLS3_k127_6043403_5	1379270.AUXF01000001_gene2557	2.52e-94	322.0	COG1878@1|root,COG1878@2|Bacteria,1ZV5N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
TLS3_k127_6043403_9	243365.CV_0304	1.248e-46	173.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,2VJ5U@28216|Betaproteobacteria,2KPGS@206351|Neisseriales	206351|Neisseriales	S	EamA-like transporter family	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
TLS3_k127_6046631_9	404589.Anae109_0558	5.87e-51	197.0	COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,42QX9@68525|delta/epsilon subdivisions,2WKS8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	PFAM Major facilitator superfamily	-	-	-	ko:K08224	-	-	-	-	ko00000,ko02000	2.A.1.36	-	-	MFS_1
TLS3_k127_6046631_11	1048983.EL17_04325	3.332e-05	56.0	COG4775@1|root,COG4775@2|Bacteria,4NMIQ@976|Bacteroidetes,47PGI@768503|Cytophagia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
TLS3_k127_6046631_10	290397.Adeh_0477	1.299e-38	151.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2WPXK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM peptidase M52 hydrogen uptake protein	hyaP	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	iAF987.Gmet_3329	HycI
TLS3_k127_6046631_0	404589.Anae109_0523	5.52e-272	846.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2WJQS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hybL	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
TLS3_k127_6046631_6	404589.Anae109_3524	6.835e-108	362.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42PH3@68525|delta/epsilon subdivisions,2WJZH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
TLS3_k127_6046631_8	290397.Adeh_0480	2.065e-99	342.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42S59@68525|delta/epsilon subdivisions,2WNGW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	hybA	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,TAT_signal
TLS3_k127_6046631_2	404589.Anae109_0526	1.801e-165	536.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2WIW4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM hydrogenase (NiFe) small subunit (hydA)	hybS	-	1.12.2.1,1.12.99.6	ko:K06282,ko:K18008	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
TLS3_k127_6046631_4	62928.azo3805	1.182e-162	526.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KUEY@206389|Rhodocyclales	206389|Rhodocyclales	T	Bacterial regulatory protein, Fis family	hoxA	-	-	ko:K19641	ko02020,map02020	M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_6046631_3	62928.azo3807	7.115e-163	522.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,2VKE2@28216|Betaproteobacteria,2KVZC@206389|Rhodocyclales	206389|Rhodocyclales	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	hoxB	-	1.12.7.2	ko:K00534	-	-	R00019	-	ko00000,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
TLS3_k127_6046631_1	748247.AZKH_3785	4.286e-187	595.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VKZS@28216|Betaproteobacteria,2KUS6@206389|Rhodocyclales	206389|Rhodocyclales	C	Nickel-dependent hydrogenase	hoxC	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
TLS3_k127_6046631_7	748247.AZKH_3784	3.078e-103	366.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,2KV0D@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	hoxJ	-	2.7.13.3	ko:K19661	ko02020,map02020	M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4
TLS3_k127_6046631_5	404589.Anae109_2957	1.185e-108	354.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,42MBH@68525|delta/epsilon subdivisions,2WK79@28221|Deltaproteobacteria,2YV9G@29|Myxococcales	28221|Deltaproteobacteria	H	aminotransferase	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
TLS3_k127_6066456_1	290397.Adeh_4252	2.285e-53	188.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2YUPP@29|Myxococcales	28221|Deltaproteobacteria	H	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
TLS3_k127_6066456_2	1452536.JARE01000016_gene2173	2.534e-05	52.0	COG4767@1|root,COG4767@2|Bacteria	2|Bacteria	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
TLS3_k127_6066456_0	290397.Adeh_4255	5.395e-101	349.0	COG0477@1|root,COG2814@2|Bacteria,1N5ZF@1224|Proteobacteria,438JY@68525|delta/epsilon subdivisions,2X3UK@28221|Deltaproteobacteria,2YX51@29|Myxococcales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_6066456_4	565045.NOR51B_1003	0.0005579	50.0	COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,1S5X2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6084547_1	404589.Anae109_1263	1.982e-221	712.0	COG0008@1|root,COG0064@1|root,COG0008@2|Bacteria,COG0064@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2YUA8@29|Myxococcales	28221|Deltaproteobacteria	J	glutaminyl-tRNA	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
TLS3_k127_6084547_0	290397.Adeh_2597	1.807e-253	787.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,2YV5P@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
TLS3_k127_6084547_7	404589.Anae109_1265	2.421e-35	140.0	2EHJS@1|root,33BBN@2|Bacteria,1NP80@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6084547_6	404589.Anae109_1266	1.069e-36	153.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Cu-binding_MopE,DUF4214,Glyco_hydro_16,Peptidase_M10
TLS3_k127_6084547_3	290397.Adeh_2594	3.561e-95	318.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2Z304@29|Myxococcales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
TLS3_k127_6084547_5	290397.Adeh_2593	1.91e-44	164.0	COG0745@1|root,COG0745@2|Bacteria	290397.Adeh_2593|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6084547_4	404589.Anae109_1269	4.32e-82	287.0	COG1266@1|root,COG1266@2|Bacteria,1NHPM@1224|Proteobacteria	1224|Proteobacteria	S	Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
TLS3_k127_6084547_2	290397.Adeh_2590	2.479e-170	548.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,42P1T@68525|delta/epsilon subdivisions,2WKZB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
TLS3_k127_6084547_8	349520.PPE_00529	4.528e-24	117.0	COG2203@1|root,COG2208@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3829@2|Bacteria,1V5VQ@1239|Firmicutes,4IQ2P@91061|Bacilli,26UXZ@186822|Paenibacillaceae	91061|Bacilli	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	PAS_9,SpoIIE
TLS3_k127_6084547_9	1156844.KB891850_gene3281	7.542e-16	91.0	COG0745@1|root,COG0745@2|Bacteria,2GMZ7@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_6084547_10	404589.Anae109_1271	7.517e-06	48.0	COG0121@1|root,COG0121@2|Bacteria,1PXTX@1224|Proteobacteria,434UP@68525|delta/epsilon subdivisions,2WZ5R@28221|Deltaproteobacteria,2Z1DW@29|Myxococcales	28221|Deltaproteobacteria	S	Glutamine amidotransferases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
TLS3_k127_6093866_0	1499967.BAYZ01000167_gene6760	1.824e-108	377.0	COG2204@1|root,COG3829@1|root,COG2204@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	ko:K15836	-	-	-	-	ko00000,ko03000	-	-	-	GAF_2,HTH_8,PAS_9,Response_reg,Sigma54_activat
TLS3_k127_6093866_1	1242864.D187_004282	1.718e-66	238.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PDY@68525|delta/epsilon subdivisions,2WMD0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
TLS3_k127_6113911_0	290397.Adeh_1400	1.066e-296	926.0	COG0460@1|root,COG2021@1|root,COG0460@2|Bacteria,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,42N1M@68525|delta/epsilon subdivisions,2WJRJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Homoserine_dh,NAD_binding_3
TLS3_k127_6113911_2	290397.Adeh_0269	1.572e-46	181.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_6113911_1	404589.Anae109_2949	4.869e-102	336.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,42S9X@68525|delta/epsilon subdivisions,2WNTZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
TLS3_k127_6128563_0	290397.Adeh_0273	4.91e-123	397.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2WJH5@28221|Deltaproteobacteria,2YTZQ@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
TLS3_k127_6128563_1	404589.Anae109_0294	9.27e-105	343.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria,2YVCJ@29|Myxococcales	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
TLS3_k127_6128563_2	290397.Adeh_0220	1.593e-99	334.0	COG1943@1|root,COG1943@2|Bacteria,1RBFM@1224|Proteobacteria,42QPI@68525|delta/epsilon subdivisions,2WMUC@28221|Deltaproteobacteria,2Z0AC@29|Myxococcales	28221|Deltaproteobacteria	L	High confidence in function and specificity	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
TLS3_k127_6128563_3	502025.Hoch_0369	5.309e-11	71.0	COG2340@1|root,COG2340@2|Bacteria,1REVB@1224|Proteobacteria,4386P@68525|delta/epsilon subdivisions,2X3GI@28221|Deltaproteobacteria,2YW01@29|Myxococcales	28221|Deltaproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
TLS3_k127_6130039_3	290397.Adeh_2467	1.535e-53	193.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2YU6X@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
TLS3_k127_6130039_1	404589.Anae109_0378	1.084e-73	259.0	COG3306@1|root,COG3306@2|Bacteria,1NGNU@1224|Proteobacteria	1224|Proteobacteria	M	PFAM glycosyl transferase family 25	-	-	-	ko:K07270	-	-	-	-	ko00000	-	GT25	-	Glyco_transf_25
TLS3_k127_6130039_0	290397.Adeh_2468	2.218e-274	851.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,2YTYA@29|Myxococcales	28221|Deltaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
TLS3_k127_6130039_2	404589.Anae109_1398	1.79e-72	248.0	COG0568@1|root,COG0568@2|Bacteria,1PBSF@1224|Proteobacteria,433T8@68525|delta/epsilon subdivisions,2X9VU@28221|Deltaproteobacteria,2YVGG@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma-70, region 4	asgB	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
TLS3_k127_6130039_4	290397.Adeh_2470	3.105e-28	117.0	COG0789@1|root,COG0789@2|Bacteria,1Q2FZ@1224|Proteobacteria,4382B@68525|delta/epsilon subdivisions,2X3CF@28221|Deltaproteobacteria,2YVED@29|Myxococcales	28221|Deltaproteobacteria	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
TLS3_k127_6133726_4	593907.Celgi_0640	7.728e-28	124.0	COG0596@1|root,COG0596@2|Bacteria,2GKJB@201174|Actinobacteria	201174|Actinobacteria	EGP	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons	dhmA2	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
TLS3_k127_6133726_0	204669.Acid345_2395	2.934e-136	468.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
TLS3_k127_6133726_1	402777.KB235903_gene1743	9.904e-116	391.0	COG3386@1|root,COG3386@2|Bacteria,1G1H9@1117|Cyanobacteria	1117|Cyanobacteria	G	Major royal jelly protein	-	-	-	-	-	-	-	-	-	-	-	-	MRJP
TLS3_k127_6133726_3	373903.Hore_19260	1.362e-64	241.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	-	-	-	ko:K13276,ko:K17734	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarboxypepD_reg,Cu_amine_oxidN1,Inhibitor_I9,LRR_5,PPC,Peptidase_S8
TLS3_k127_6133726_5	1390370.O203_07680	7.615e-09	65.0	COG2378@1|root,COG2378@2|Bacteria,1PXCX@1224|Proteobacteria,1RR3V@1236|Gammaproteobacteria,1YH5R@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
TLS3_k127_6135203_1	1279038.KB907341_gene1895	4.317e-60	212.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,2UAJA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
TLS3_k127_6135203_0	404589.Anae109_0866	3.916e-160	510.0	COG3837@1|root,COG3837@2|Bacteria,1N69J@1224|Proteobacteria	1224|Proteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_6147903_4	290397.Adeh_1149	7.372e-60	212.0	2DQBG@1|root,335T7@2|Bacteria,1R35T@1224|Proteobacteria,42ZVK@68525|delta/epsilon subdivisions,2WV6B@28221|Deltaproteobacteria,2YW08@29|Myxococcales	28221|Deltaproteobacteria	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	1.21.4.1	ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
TLS3_k127_6147903_6	404589.Anae109_1195	2.621e-48	174.0	COG1225@1|root,COG1225@2|Bacteria,1N9JS@1224|Proteobacteria,42R82@68525|delta/epsilon subdivisions,2WMVA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
TLS3_k127_6147903_9	404589.Anae109_1194	2.712e-20	92.0	COG0450@1|root,COG0450@2|Bacteria	2|Bacteria	O	alkyl hydroperoxide reductase	-	-	1.11.1.15	ko:K03386,ko:K03564	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
TLS3_k127_6147903_8	290397.Adeh_1147	1.897e-26	111.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
TLS3_k127_6147903_0	404589.Anae109_1190	8.397e-215	686.0	COG1012@1|root,COG1012@2|Bacteria,1R528@1224|Proteobacteria,433YD@68525|delta/epsilon subdivisions,2X42A@28221|Deltaproteobacteria,2YY1Y@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.5	ko:K00129	ko00010,ko00340,ko00350,ko00360,ko00410,ko00980,ko00982,ko01100,ko01110,ko01120,ko05204,map00010,map00340,map00350,map00360,map00410,map00980,map00982,map01100,map01110,map01120,map05204	-	R00711,R00904,R02536,R02537,R02695,R02697,R03300,R03302,R04882,R04883,R04888,R04889,R04891,R04892,R04996,R07104,R08282,R08283,R08307	RC00047,RC00080,RC00242,RC01735	ko00000,ko00001,ko01000	-	-	-	Aldedh
TLS3_k127_6147903_2	1254432.SCE1572_00530	2.605e-68	242.0	COG0783@1|root,COG0783@2|Bacteria	2|Bacteria	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
TLS3_k127_6147903_5	290397.Adeh_1140	1.928e-49	188.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,42SPA@68525|delta/epsilon subdivisions,2WPPE@28221|Deltaproteobacteria,2YVJ2@29|Myxococcales	28221|Deltaproteobacteria	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
TLS3_k127_6147903_3	404589.Anae109_1187	1.633e-65	225.0	COG1351@1|root,COG1351@2|Bacteria,1Q73I@1224|Proteobacteria,42N3X@68525|delta/epsilon subdivisions,2WN7U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
TLS3_k127_6169414_2	290397.Adeh_3776	2.435e-75	264.0	COG1589@1|root,COG1589@2|Bacteria,1RDX7@1224|Proteobacteria,42VCZ@68525|delta/epsilon subdivisions,2WRVM@28221|Deltaproteobacteria,2YVR5@29|Myxococcales	28221|Deltaproteobacteria	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
TLS3_k127_6169414_0	404589.Anae109_3893	2.062e-234	742.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2YTZH@29|Myxococcales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
TLS3_k127_6169414_1	404589.Anae109_3894	4.961e-154	496.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,2YTTW@29|Myxococcales	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
TLS3_k127_620668_2	290397.Adeh_2639	5.053e-91	332.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42UIR@68525|delta/epsilon subdivisions,2WTWT@28221|Deltaproteobacteria,2Z2XU@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_620668_1	290397.Adeh_2640	1.29e-121	403.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
TLS3_k127_620668_0	290397.Adeh_2641	3.479e-162	516.0	COG0438@1|root,COG0438@2|Bacteria,1QU2N@1224|Proteobacteria,42PY5@68525|delta/epsilon subdivisions,2WIU8@28221|Deltaproteobacteria,2YVJ5@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	tuaH	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
TLS3_k127_6210381_3	290397.Adeh_3525	1.755e-17	83.0	2AHPH@1|root,3181M@2|Bacteria,1PA0C@1224|Proteobacteria,432I6@68525|delta/epsilon subdivisions,2WY33@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6210381_0	1217718.ALOU01000086_gene1843	5.315e-103	340.0	COG0426@1|root,COG0426@2|Bacteria,1MXIE@1224|Proteobacteria,2W9V7@28216|Betaproteobacteria,1K54Q@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_6210381_2	290397.Adeh_0224	9.788e-49	186.0	COG3568@1|root,COG3568@2|Bacteria,1N29G@1224|Proteobacteria	1224|Proteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_6210381_1	404589.Anae109_2787	1.062e-90	302.0	COG1913@1|root,COG1913@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
TLS3_k127_6227337_1	404589.Anae109_2716	5.437e-123	399.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,42R48@68525|delta/epsilon subdivisions,2WMAR@28221|Deltaproteobacteria,2YUR9@29|Myxococcales	28221|Deltaproteobacteria	E	MazG nucleotide pyrophosphohydrolase domain	mazG	-	3.6.1.9	ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
TLS3_k127_6227337_3	1280668.ATVT01000002_gene2958	1.282e-11	70.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,4BZWR@830|Butyrivibrio	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
TLS3_k127_6227337_0	404589.Anae109_2719	6.675e-267	828.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
TLS3_k127_6228632_3	644282.Deba_3003	1.184e-25	112.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	bgeR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
TLS3_k127_6228632_0	584708.Apau_2422	1.87e-231	730.0	COG0369@1|root,COG1151@2|Bacteria,3TA79@508458|Synergistetes	508458|Synergistetes	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
TLS3_k127_6228632_1	1041147.AUFB01000005_gene2568	4.806e-64	228.0	COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,2UARY@28211|Alphaproteobacteria,4BE5B@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Uncharacterized protein family, UPF0114	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
TLS3_k127_6228632_2	404589.Anae109_0901	2.386e-47	172.0	COG4681@1|root,COG4681@2|Bacteria	2|Bacteria	S	YaeQ	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
TLS3_k127_6233839_5	404589.Anae109_1629	1.338e-46	174.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WKYQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	TIGRFAM para-aminobenzoate synthase, subunit I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
TLS3_k127_6233839_6	861299.J421_0777	4.742e-45	168.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
TLS3_k127_6233839_7	378806.STAUR_7283	1.083e-44	171.0	COG3744@1|root,COG3744@2|Bacteria,1NY7K@1224|Proteobacteria,4380D@68525|delta/epsilon subdivisions,2X3AF@28221|Deltaproteobacteria,2YV4N@29|Myxococcales	28221|Deltaproteobacteria	S	PilT protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6233839_10	398527.Bphyt_6150	1.446e-20	104.0	COG1011@1|root,COG1011@2|Bacteria,1NYX7@1224|Proteobacteria,2W1D6@28216|Betaproteobacteria,1KGBW@119060|Burkholderiaceae	28216|Betaproteobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like)	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	Hydrolase
TLS3_k127_6233839_4	483219.LILAB_35200	3.194e-89	321.0	COG0569@1|root,COG0569@2|Bacteria,1R7KM@1224|Proteobacteria,42PJH@68525|delta/epsilon subdivisions,2WMZT@28221|Deltaproteobacteria,2YVX6@29|Myxococcales	28221|Deltaproteobacteria	C	TrkA-C domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
TLS3_k127_6233839_1	483219.LILAB_35205	4.204e-176	565.0	COG0168@1|root,COG0168@2|Bacteria,1N412@1224|Proteobacteria,42MBI@68525|delta/epsilon subdivisions,2WIZ9@28221|Deltaproteobacteria,2YURM@29|Myxococcales	28221|Deltaproteobacteria	P	Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
TLS3_k127_6233839_9	404589.Anae109_2833	2.061e-21	109.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,4315I@68525|delta/epsilon subdivisions,2WWPX@28221|Deltaproteobacteria,2YVPZ@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
TLS3_k127_6233839_0	1278073.MYSTI_02531	1.921e-305	951.0	COG1858@1|root,COG1858@2|Bacteria,1MWAT@1224|Proteobacteria,42Y6Q@68525|delta/epsilon subdivisions,2WU96@28221|Deltaproteobacteria,2YVFI@29|Myxococcales	28221|Deltaproteobacteria	C	Di-haem cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
TLS3_k127_6233839_2	404589.Anae109_0481	6.213e-170	536.0	COG0596@1|root,COG0596@2|Bacteria,1MUVB@1224|Proteobacteria,42WB3@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Alpha beta hydrolase	dehH	-	3.8.1.3	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
TLS3_k127_6233839_8	290397.Adeh_0744	6.194e-25	109.0	2DXRH@1|root,3465W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6233839_3	404589.Anae109_0191	2.882e-142	458.0	COG1163@1|root,COG1163@2|Bacteria,1RFPD@1224|Proteobacteria,42ZF3@68525|delta/epsilon subdivisions,2WUZY@28221|Deltaproteobacteria,2Z0K4@29|Myxococcales	28221|Deltaproteobacteria	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
TLS3_k127_6266380_3	290397.Adeh_3308	4.652e-102	345.0	COG1355@1|root,COG1355@2|Bacteria,1N5H1@1224|Proteobacteria,42TIN@68525|delta/epsilon subdivisions,2WR24@28221|Deltaproteobacteria,2Z1BF@29|Myxococcales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
TLS3_k127_6266380_0	1144275.COCOR_02571	3.763e-216	689.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2WINB@28221|Deltaproteobacteria,2YUHB@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
TLS3_k127_6266380_4	290397.Adeh_3306	4.643e-54	193.0	COG4911@1|root,COG4911@2|Bacteria,1QCSX@1224|Proteobacteria,4387P@68525|delta/epsilon subdivisions,2X3HG@28221|Deltaproteobacteria,2YW4D@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
TLS3_k127_6266380_2	404589.Anae109_0539	1.004e-153	506.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
TLS3_k127_6266380_1	404589.Anae109_0540	3.083e-179	599.0	COG0784@1|root,COG0840@1|root,COG1511@1|root,COG2770@1|root,COG5002@1|root,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BZ2@68525|delta/epsilon subdivisions,2X79T@28221|Deltaproteobacteria,2YU1H@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
TLS3_k127_6287232_4	404589.Anae109_0355	8.095e-104	342.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2WJKT@28221|Deltaproteobacteria,2YZXG@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
TLS3_k127_6287232_2	290397.Adeh_4069	9.665e-150	478.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,2YUVE@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
TLS3_k127_6287232_1	290397.Adeh_4070	1.06e-196	627.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria,2YUK3@29|Myxococcales	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS3_k127_6287232_0	404589.Anae109_0352	4.858e-223	713.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2WIRN@28221|Deltaproteobacteria,2YV9Y@29|Myxococcales	28221|Deltaproteobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1,NUDIX
TLS3_k127_6287232_6	404589.Anae109_0351	2.994e-59	208.0	COG1765@1|root,COG1765@2|Bacteria,1QF2H@1224|Proteobacteria,42VZN@68525|delta/epsilon subdivisions,2WSEZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC
TLS3_k127_6287232_3	404589.Anae109_0350	4.003e-140	470.0	2AIV6@1|root,319CD@2|Bacteria,1Q2BD@1224|Proteobacteria,437XV@68525|delta/epsilon subdivisions,2X37S@28221|Deltaproteobacteria,2YUR7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6287232_5	404589.Anae109_0349	7.993e-65	222.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,42URG@68525|delta/epsilon subdivisions,2WNDG@28221|Deltaproteobacteria,2YVX9@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase-like domain	mceE	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
TLS3_k127_6298331_14	1242864.D187_006866	2.561e-12	75.0	COG0745@1|root,COG0745@2|Bacteria,1N1N5@1224|Proteobacteria,42UP1@68525|delta/epsilon subdivisions,2WQAF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_6298331_0	404589.Anae109_1477	0.0	1443.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,2YXPT@29|Myxococcales	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
TLS3_k127_6298331_5	290397.Adeh_2389	3.203e-136	437.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2WJH7@28221|Deltaproteobacteria,2YUYQ@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1988	QRPTase_C,QRPTase_N
TLS3_k127_6298331_3	290397.Adeh_2388	2.578e-148	475.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,2YVIU@29|Myxococcales	28221|Deltaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
TLS3_k127_6298331_7	404589.Anae109_1480	3.97e-130	419.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,42MVZ@68525|delta/epsilon subdivisions,2WJ3N@28221|Deltaproteobacteria,2YTUR@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1986	Pan_kinase
TLS3_k127_6298331_10	404589.Anae109_1481	1.044e-46	184.0	COG0457@1|root,COG0457@2|Bacteria,1P4QM@1224|Proteobacteria,4334V@68525|delta/epsilon subdivisions,2WX62@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
TLS3_k127_6298331_2	290397.Adeh_2385	7.652e-166	528.0	2DMMW@1|root,32SIJ@2|Bacteria,1N004@1224|Proteobacteria,42TSJ@68525|delta/epsilon subdivisions,2WQHG@28221|Deltaproteobacteria,2YV84@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6298331_1	290397.Adeh_2384	1.759e-211	668.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2YVGD@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
TLS3_k127_6298331_15	290397.Adeh_2383	7.864e-10	63.0	COG4575@1|root,COG4575@2|Bacteria	2|Bacteria	T	ribosome binding	MA20_18275	-	-	-	-	-	-	-	-	-	-	-	DUF883
TLS3_k127_6298331_11	404589.Anae109_1487	4.305e-30	138.0	COG0745@1|root,COG1196@1|root,COG0745@2|Bacteria,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	frzS	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_6298331_9	404589.Anae109_1488	2.943e-67	238.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
TLS3_k127_6298331_8	290397.Adeh_2378	1.248e-113	371.0	COG1595@1|root,COG1595@2|Bacteria,1PEJM@1224|Proteobacteria,4380A@68525|delta/epsilon subdivisions,2X3AB@28221|Deltaproteobacteria,2YV3Y@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_6298331_6	309801.trd_1056	4.005e-133	435.0	COG0686@1|root,COG0686@2|Bacteria,2G68X@200795|Chloroflexi,27YU4@189775|Thermomicrobia	189775|Thermomicrobia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
TLS3_k127_6298331_4	290397.Adeh_2377	2.052e-140	453.0	COG2896@1|root,COG2896@2|Bacteria,1MXMH@1224|Proteobacteria,42NTM@68525|delta/epsilon subdivisions,2WKIQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TLS3_k127_6344610_3	404589.Anae109_1773	9.311e-108	359.0	COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,42MX2@68525|delta/epsilon subdivisions,2WIUV@28221|Deltaproteobacteria,2Z2KR@29|Myxococcales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_6344610_2	290397.Adeh_2041	5.393e-142	466.0	COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,42Q9D@68525|delta/epsilon subdivisions,2WK21@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
TLS3_k127_6344610_1	1242864.D187_005023	1.719e-164	533.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria,2YWIW@29|Myxococcales	28221|Deltaproteobacteria	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
TLS3_k127_6344610_5	448385.sce6791	3.033e-53	214.0	COG2120@1|root,COG2120@2|Bacteria,1RJX0@1224|Proteobacteria,430YJ@68525|delta/epsilon subdivisions,2WVVM@28221|Deltaproteobacteria,2Z16I@29|Myxococcales	28221|Deltaproteobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TLS3_k127_6344610_4	1380394.JADL01000022_gene27	8.359e-102	357.0	COG0438@1|root,COG0438@2|Bacteria,1MWSZ@1224|Proteobacteria,2TR5P@28211|Alphaproteobacteria,2JPNU@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
TLS3_k127_6344610_0	404589.Anae109_1780	7.424e-269	835.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,42M9F@68525|delta/epsilon subdivisions,2WJNB@28221|Deltaproteobacteria,2YU00@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TLS3_k127_6349248_0	290397.Adeh_2467	9.784e-148	475.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2YU6X@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
TLS3_k127_6349248_3	404589.Anae109_1401	9.622e-75	254.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2WPG2@28221|Deltaproteobacteria,2Z2Z7@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
TLS3_k127_6349248_1	290397.Adeh_2465	6.008e-110	366.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2WKHT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
TLS3_k127_6349248_2	404589.Anae109_4195	4.382e-100	347.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,42N5X@68525|delta/epsilon subdivisions,2WJ3H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
TLS3_k127_6349248_4	404589.Anae109_1404	1.025e-65	254.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
TLS3_k127_6349248_5	404589.Anae109_1409	4.633e-05	46.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,42PK2@68525|delta/epsilon subdivisions,2WP9Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	2.4.1.349	ko:K12994	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_6351758_5	404589.Anae109_3049	5.866e-50	183.0	COG0484@1|root,COG0484@2|Bacteria,1QYGD@1224|Proteobacteria,43CCI@68525|delta/epsilon subdivisions,2X7NG@28221|Deltaproteobacteria,2Z1CZ@29|Myxococcales	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	GSu_C4xC__C2xCH
TLS3_k127_6351758_2	1192034.CAP_8570	2.316e-90	310.0	COG3000@1|root,COG3000@2|Bacteria,1NR7X@1224|Proteobacteria,43B2H@68525|delta/epsilon subdivisions,2X6GI@28221|Deltaproteobacteria,2YUTY@29|Myxococcales	28221|Deltaproteobacteria	I	Sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
TLS3_k127_6351758_6	2002.JOEQ01000038_gene4179	1.031e-31	143.0	COG5207@1|root,COG5207@2|Bacteria,2IKW9@201174|Actinobacteria,4EKBJ@85012|Streptosporangiales	201174|Actinobacteria	O	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
TLS3_k127_6351758_0	1380393.JHVP01000003_gene1104	2.512e-159	521.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4ERPW@85013|Frankiales	2|Bacteria	KOT	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
TLS3_k127_6351758_3	1173021.ALWA01000037_gene3499	4.331e-64	243.0	COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria	1117|Cyanobacteria	J	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
TLS3_k127_6351758_1	1123368.AUIS01000024_gene954	2.296e-144	478.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amino acid	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
TLS3_k127_6351758_4	404589.Anae109_1988	1.355e-62	218.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria,2YU4T@29|Myxococcales	28221|Deltaproteobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
TLS3_k127_6365933_10	404589.Anae109_0945	4.028e-32	127.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42S2J@68525|delta/epsilon subdivisions	1224|Proteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_6365933_2	290397.Adeh_0899	8.956e-105	351.0	COG0842@1|root,COG0842@2|Bacteria,1MVUG@1224|Proteobacteria,42US7@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
TLS3_k127_6365933_6	290397.Adeh_0898	2.583e-54	206.0	COG2322@1|root,COG2322@2|Bacteria,1NF1F@1224|Proteobacteria,43BE2@68525|delta/epsilon subdivisions,2X6SJ@28221|Deltaproteobacteria,2Z3CM@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
TLS3_k127_6365933_3	404589.Anae109_2841	6.403e-96	318.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,43ADI@68525|delta/epsilon subdivisions,2WPU6@28221|Deltaproteobacteria,2Z38F@29|Myxococcales	28221|Deltaproteobacteria	H	Reversible hydration of carbon dioxide	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
TLS3_k127_6365933_5	1242864.D187_004972	1.996e-59	215.0	COG1999@1|root,COG1999@2|Bacteria,1N19Q@1224|Proteobacteria,42XV1@68525|delta/epsilon subdivisions,2WSUD@28221|Deltaproteobacteria,2YV76@29|Myxococcales	28221|Deltaproteobacteria	S	protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
TLS3_k127_6365933_7	290397.Adeh_0888	1.78e-53	209.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	bcr4	-	-	ko:K21007	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	TPR_15,TPR_16,TPR_19,TPR_2
TLS3_k127_6365933_1	404589.Anae109_0941	2.679e-134	437.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,42M92@68525|delta/epsilon subdivisions,2WJ7J@28221|Deltaproteobacteria,2YVBA@29|Myxococcales	28221|Deltaproteobacteria	M	PFAM MscS Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
TLS3_k127_6365933_0	404589.Anae109_0864	2.322e-302	942.0	COG3973@1|root,COG3973@2|Bacteria,1MZQF@1224|Proteobacteria,42UXS@68525|delta/epsilon subdivisions,2WQJ8@28221|Deltaproteobacteria,2YYYK@29|Myxococcales	28221|Deltaproteobacteria	L	UvrD-like helicase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD-helicase,UvrD_C_2
TLS3_k127_6365933_8	404589.Anae109_0916	3.378e-36	143.0	COG0748@1|root,COG0748@2|Bacteria,1RFVC@1224|Proteobacteria,42UK2@68525|delta/epsilon subdivisions,2WR4V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Protein of unknown function (DUF2470)	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Pyrid_oxidase_2
TLS3_k127_6365933_4	29306.JOBE01000001_gene2614	2.106e-80	280.0	COG3568@1|root,COG3568@2|Bacteria,2IGGC@201174|Actinobacteria	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_6365933_9	290397.Adeh_1435	1.04e-33	132.0	COG0697@1|root,COG0697@2|Bacteria,1RBQS@1224|Proteobacteria,42U3T@68525|delta/epsilon subdivisions,2WQAP@28221|Deltaproteobacteria,2Z2VR@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_6418240_2	290397.Adeh_1232	2.133e-53	190.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2YVEN@29|Myxococcales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
TLS3_k127_6418240_1	404589.Anae109_2536	1.582e-132	443.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2WJ0Q@28221|Deltaproteobacteria,2YVDN@29|Myxococcales	28221|Deltaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
TLS3_k127_6418240_0	404589.Anae109_2537	1.02e-184	580.0	COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,42NBQ@68525|delta/epsilon subdivisions,2WKR5@28221|Deltaproteobacteria,2YUIB@29|Myxococcales	28221|Deltaproteobacteria	T	PrkA AAA domain	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
TLS3_k127_6423036_1	290397.Adeh_0123	6.255e-106	355.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
TLS3_k127_6423036_4	997346.HMPREF9374_2688	7.564e-17	86.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,4HIPT@91061|Bacilli,27C54@186824|Thermoactinomycetaceae	91061|Bacilli	M	SpoVG	spoVG	GO:0000003,GO:0008150,GO:0019954,GO:0030436,GO:0032502,GO:0043934	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
TLS3_k127_6423036_0	290397.Adeh_0121	7.274e-164	521.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2WJ5W@28221|Deltaproteobacteria,2YUB9@29|Myxococcales	28221|Deltaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
TLS3_k127_6423036_3	290397.Adeh_0120	2.372e-70	266.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,42RVM@68525|delta/epsilon subdivisions,2WQIY@28221|Deltaproteobacteria,2YVJV@29|Myxococcales	28221|Deltaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
TLS3_k127_6423036_2	404589.Anae109_0123	5.464e-86	289.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,42RGU@68525|delta/epsilon subdivisions,2WPHH@28221|Deltaproteobacteria,2YZP7@29|Myxococcales	28221|Deltaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
TLS3_k127_6427641_1	365044.Pnap_0028	4.011e-78	276.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,2WGER@28216|Betaproteobacteria,4AD7W@80864|Comamonadaceae	28216|Betaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
TLS3_k127_6427641_3	290397.Adeh_2980	3.859e-47	176.0	COG4235@1|root,COG4235@2|Bacteria,1RITV@1224|Proteobacteria,43CCM@68525|delta/epsilon subdivisions,2X7NI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
TLS3_k127_6427641_4	404589.Anae109_3473	1.326e-41	158.0	COG1186@1|root,COG1186@2|Bacteria,1ND5C@1224|Proteobacteria,430VS@68525|delta/epsilon subdivisions,2WW3U@28221|Deltaproteobacteria,2Z2GT@29|Myxococcales	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
TLS3_k127_6427641_6	1122929.KB908217_gene153	2.779e-14	77.0	2DPXH@1|root,333TM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6427641_5	290397.Adeh_0860	5.255e-34	136.0	COG0023@1|root,COG0023@2|Bacteria	2|Bacteria	J	translation initiation factor activity	yciH	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
TLS3_k127_6427641_2	404589.Anae109_4053	1.031e-70	243.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,42SN0@68525|delta/epsilon subdivisions,2WPY6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
TLS3_k127_6427641_0	404589.Anae109_1755	9.753e-200	636.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,43C89@68525|delta/epsilon subdivisions,2X7IN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TLS3_k127_6439272_0	404589.Anae109_0189	0.0	1765.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2YVGM@29|Myxococcales	28221|Deltaproteobacteria	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
TLS3_k127_6439272_1	290397.Adeh_0102	6.156e-97	321.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42PZF@68525|delta/epsilon subdivisions,2X5HR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_6459230_6	290397.Adeh_3772	1.097e-07	53.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2YTUP@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_6459230_1	404589.Anae109_3884	5.446e-185	604.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2YWEZ@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
TLS3_k127_6459230_4	404589.Anae109_3883	1.933e-124	411.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,2YTX5@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
TLS3_k127_6459230_3	290397.Adeh_3769	1.426e-179	592.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria,2YU89@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8
TLS3_k127_6459230_0	290397.Adeh_3768	7.107e-187	589.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2WJDS@28221|Deltaproteobacteria,2YWXN@29|Myxococcales	28221|Deltaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409	Glycos_transf_4,MraY_sig1
TLS3_k127_6459230_2	290397.Adeh_3767	1.358e-182	584.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria,2YXRU@29|Myxococcales	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_6459230_5	404589.Anae109_3879	6.818e-123	404.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2WJJG@28221|Deltaproteobacteria,2YU1E@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_6510095_0	290397.Adeh_0567	0.0	1076.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,42QIF@68525|delta/epsilon subdivisions,2WKM9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	RNA polymerase recycling family C-terminal	rapA	-	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Helicase_C,RapA_C,SNF2_N
TLS3_k127_6510095_2	215803.DB30_3885	1.466e-72	261.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,430V0@68525|delta/epsilon subdivisions,2WVT6@28221|Deltaproteobacteria,2YXP7@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
TLS3_k127_6510095_4	84531.JMTZ01000038_gene3588	4.675e-29	124.0	2EFPP@1|root,339FP@2|Bacteria,1NA60@1224|Proteobacteria,1SH3I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
TLS3_k127_6510095_1	290397.Adeh_0444	4.337e-139	453.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42N9C@68525|delta/epsilon subdivisions,2WJ2J@28221|Deltaproteobacteria,2YXSZ@29|Myxococcales	28221|Deltaproteobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
TLS3_k127_6510095_3	290397.Adeh_3508	4.005e-49	177.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,42S1N@68525|delta/epsilon subdivisions,2WNUH@28221|Deltaproteobacteria,2Z1FH@29|Myxococcales	28221|Deltaproteobacteria	O	Thioredoxin	trx-3	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
TLS3_k127_6554942_2	502025.Hoch_6401	4.501e-54	203.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	ko:K03496,ko:K22491	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	B12-binding_2,DUF3967,HTH_17,MerR_1
TLS3_k127_6554942_3	861299.J421_4086	6.263e-45	181.0	COG4846@1|root,COG4846@2|Bacteria	2|Bacteria	O	Membrane protein involved in cytochrome C biogenesis	yneJ	-	-	-	-	-	-	-	-	-	-	-	DUF1453
TLS3_k127_6554942_0	159087.Daro_2072	9.315e-157	507.0	COG0025@1|root,COG0025@2|Bacteria,1QA7B@1224|Proteobacteria,2VHPR@28216|Betaproteobacteria,2KUTD@206389|Rhodocyclales	206389|Rhodocyclales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
TLS3_k127_6554942_1	290397.Adeh_1182	9.081e-58	206.0	COG1051@1|root,COG1051@2|Bacteria,1N5QT@1224|Proteobacteria,433SX@68525|delta/epsilon subdivisions,2WXYA@28221|Deltaproteobacteria,2YVMP@29|Myxococcales	28221|Deltaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_6554942_6	404589.Anae109_3547	7.039e-18	95.0	COG0457@1|root,COG0457@2|Bacteria	404589.Anae109_3547|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6554942_4	243231.GSU2789	6.676e-42	167.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
TLS3_k127_6591297_14	1123258.AQXZ01000018_gene1055	1.223e-08	57.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4FUDW@85025|Nocardiaceae	201174|Actinobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
TLS3_k127_6591297_10	105422.BBPM01000048_gene1641	6.677e-50	183.0	COG1720@1|root,COG1720@2|Bacteria,2IKKT@201174|Actinobacteria,2NIXH@228398|Streptacidiphilus	201174|Actinobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
TLS3_k127_6591297_1	290397.Adeh_3296	4.863e-229	715.0	COG0493@1|root,COG0493@2|Bacteria,1P58U@1224|Proteobacteria,4392A@68525|delta/epsilon subdivisions,2X47Z@28221|Deltaproteobacteria,2YYG2@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_6591297_8	404589.Anae109_0856	1.226e-82	283.0	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,42SUN@68525|delta/epsilon subdivisions,2WPCU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_6591297_12	502025.Hoch_5660	6.306e-36	147.0	COG4333@1|root,COG4333@2|Bacteria,1N19M@1224|Proteobacteria,42V6C@68525|delta/epsilon subdivisions,2WWGF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1643)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1643
TLS3_k127_6591297_9	661478.OP10G_0869	3.118e-64	236.0	COG1028@1|root,COG1028@2|Bacteria	661478.OP10G_0869|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6591297_7	290397.Adeh_0737	4.362e-85	293.0	COG4775@1|root,COG4775@2|Bacteria,1QUE3@1224|Proteobacteria,430IG@68525|delta/epsilon subdivisions,2WVP9@28221|Deltaproteobacteria,2YVI0@29|Myxococcales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
TLS3_k127_6591297_5	404589.Anae109_4052	9.62e-88	302.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42ZH7@68525|delta/epsilon subdivisions,2WV12@28221|Deltaproteobacteria,2Z0K0@29|Myxococcales	28221|Deltaproteobacteria	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
TLS3_k127_6591297_11	404589.Anae109_3929	7.185e-43	171.0	COG5637@1|root,COG5637@2|Bacteria,1PJX4@1224|Proteobacteria,435GH@68525|delta/epsilon subdivisions,2WZU0@28221|Deltaproteobacteria,2Z2R9@29|Myxococcales	28221|Deltaproteobacteria	S	Cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6591297_4	208439.AJAP_25800	2.451e-91	308.0	COG4221@1|root,COG4221@2|Bacteria,2GRRV@201174|Actinobacteria,4EDSG@85010|Pseudonocardiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_6591297_0	1232410.KI421422_gene2086	6.288e-265	836.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,42MEV@68525|delta/epsilon subdivisions,2WK2S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM TRAP transporter, 4TM 12TM fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	DctM
TLS3_k127_6591297_3	1121439.dsat_2637	2.821e-117	407.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,42MGJ@68525|delta/epsilon subdivisions,2WJ5E@28221|Deltaproteobacteria,2M9F5@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
TLS3_k127_6591297_2	640081.Dsui_3155	1.439e-130	427.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria,2KV1X@206389|Rhodocyclales	206389|Rhodocyclales	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
TLS3_k127_6591297_13	1000565.METUNv1_01527	3.867e-11	75.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,2KUUR@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase	dctS	-	2.7.13.3	ko:K11711	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
TLS3_k127_6591297_6	376733.IT41_17815	1.958e-87	298.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TT96@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TLS3_k127_6595612_5	404589.Anae109_2279	2.097e-24	107.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria,2YVR1@29|Myxococcales	28221|Deltaproteobacteria	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
TLS3_k127_6595612_3	404589.Anae109_2280	2.696e-104	362.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2WIQF@28221|Deltaproteobacteria,2YU88@29|Myxococcales	28221|Deltaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
TLS3_k127_6595612_1	404589.Anae109_2281	1.687e-207	651.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2WJ0B@28221|Deltaproteobacteria,2YTW5@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
TLS3_k127_6595612_2	290397.Adeh_1530	1.001e-180	572.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2WIK1@28221|Deltaproteobacteria,2YUMG@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
TLS3_k127_6595612_0	404589.Anae109_2284	1.368e-261	816.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,42MT3@68525|delta/epsilon subdivisions,2WIK5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,HI0933_like,Pyr_redox_2
TLS3_k127_6595612_4	404589.Anae109_2286	2.444e-57	201.0	COG0662@1|root,COG0662@2|Bacteria,1NADF@1224|Proteobacteria	1224|Proteobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,MannoseP_isomer
TLS3_k127_6595612_7	404589.Anae109_2287	8.395e-13	75.0	COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,42X25@68525|delta/epsilon subdivisions,2WSPI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Sporulation related domain	agmI	-	-	-	-	-	-	-	-	-	-	-	SPOR
TLS3_k127_6622049_1	404589.Anae109_0816	1.311e-91	317.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
TLS3_k127_6622049_3	290397.Adeh_2050	6.948e-58	209.0	COG1553@1|root,COG1553@2|Bacteria,1NB8E@1224|Proteobacteria,432G9@68525|delta/epsilon subdivisions,2WXTS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6622049_5	290397.Adeh_0383	1.88e-34	149.0	COG2703@1|root,COG2703@2|Bacteria,1N9YV@1224|Proteobacteria,42V6I@68525|delta/epsilon subdivisions,2WY4P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
TLS3_k127_6622049_6	448385.sce6866	3.179e-30	125.0	COG5592@1|root,COG5592@2|Bacteria	2|Bacteria	I	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Phasin_2
TLS3_k127_6622049_2	290397.Adeh_0454	4.004e-60	217.0	COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,42WF1@68525|delta/epsilon subdivisions,2WS1V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3014)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3014
TLS3_k127_6622049_4	404589.Anae109_4124	1.006e-35	147.0	COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2WS8K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
TLS3_k127_6622049_0	290397.Adeh_3019	1.386e-186	584.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2WIWB@28221|Deltaproteobacteria,2YU75@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
TLS3_k127_6641936_4	1380391.JIAS01000017_gene501	4.686e-22	113.0	COG0834@1|root,COG3852@1|root,COG0834@2|Bacteria,COG3852@2|Bacteria,1N315@1224|Proteobacteria	1224|Proteobacteria	T	Extracellular solute-binding protein family 3	-	-	2.7.13.3	ko:K07679	ko02020,ko05133,map02020,map05133	M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,PAS,PAS_4,SBP_bac_3
TLS3_k127_6641936_2	215803.DB30_0400	4.803e-104	349.0	COG1793@1|root,COG1793@2|Bacteria,1R4SI@1224|Proteobacteria,438FV@68525|delta/epsilon subdivisions,2X3QT@28221|Deltaproteobacteria,2YWVJ@29|Myxococcales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
TLS3_k127_6641936_0	290397.Adeh_0817	0.0	2487.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria,2YUAD@29|Myxococcales	28221|Deltaproteobacteria	E	Glutamate synthase	gltB1	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
TLS3_k127_6641936_1	404589.Anae109_0855	2.049e-266	826.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJZJ@28221|Deltaproteobacteria,2Z2XA@29|Myxococcales	28221|Deltaproteobacteria	C	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
TLS3_k127_6641936_5	1123519.PSJM300_14825	0.0005787	45.0	COG0582@1|root,COG0582@2|Bacteria,1N45B@1224|Proteobacteria,1RNDM@1236|Gammaproteobacteria,1Z2BV@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	COG0582 Integrase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
TLS3_k127_6641936_3	1278073.MYSTI_01975	8.392e-31	127.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_4,Phage_integrase
TLS3_k127_6669746_4	946362.XP_004987944.1	3.046e-28	132.0	COG2304@1|root,2RXR2@2759|Eukaryota	2759|Eukaryota	S	hyaluronan metabolic process	ITIH1	GO:0003674,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0043167,GO:0043169,GO:0046872	-	ko:K19014	-	-	-	-	ko00000,ko00536	-	-	-	ITI_HC_C,PH_10,VIT,VWA,VWA_3,Vwaint,zf-RING_11,zf-RING_2
TLS3_k127_6669746_1	272123.Anacy_4574	5.096e-46	185.0	COG0317@1|root,COG0317@2|Bacteria,1G0F8@1117|Cyanobacteria,1HK54@1161|Nostocales	1117|Cyanobacteria	KT	HD domain	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	HD_4
TLS3_k127_6669746_2	1242864.D187_003976	9.125e-45	169.0	COG1073@1|root,COG1073@2|Bacteria,1NY60@1224|Proteobacteria	1224|Proteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6669746_5	388051.AUFE01000004_gene969	5.784e-26	113.0	2EERN@1|root,338JC@2|Bacteria,1NCUD@1224|Proteobacteria,2VWBR@28216|Betaproteobacteria,1K9RV@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6669746_0	765420.OSCT_0508	1.207e-202	639.0	COG1960@1|root,COG1960@2|Bacteria,2G7Q9@200795|Chloroflexi,37704@32061|Chloroflexia	32061|Chloroflexia	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_6676321_3	404589.Anae109_0101	7.166e-169	531.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,42NGK@68525|delta/epsilon subdivisions,2WM29@28221|Deltaproteobacteria,2YU1M@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2768	NTP_transferase
TLS3_k127_6676321_4	1144275.COCOR_02231	1.497e-115	380.0	COG2227@1|root,COG2227@2|Bacteria,1QY93@1224|Proteobacteria,42VQY@68525|delta/epsilon subdivisions,2WRC2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
TLS3_k127_6676321_8	290397.Adeh_0099	2.286e-48	179.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,42TN9@68525|delta/epsilon subdivisions,2WRG0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
TLS3_k127_6676321_7	1123368.AUIS01000002_gene1544	4.199e-55	207.0	COG1633@1|root,COG1633@2|Bacteria,1RE1V@1224|Proteobacteria,1SPCN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the Dps family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6676321_2	1123368.AUIS01000002_gene1543	6.339e-181	574.0	COG1633@1|root,COG1633@2|Bacteria,1NMZI@1224|Proteobacteria,1SMGI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6676321_0	404589.Anae109_0098	0.0	1026.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2YU2G@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
TLS3_k127_6676321_1	404589.Anae109_0096	4.151e-245	774.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2WIQ9@28221|Deltaproteobacteria,2YXJ9@29|Myxococcales	28221|Deltaproteobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
TLS3_k127_6676321_6	404589.Anae109_0095	6.866e-73	248.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,42SVZ@68525|delta/epsilon subdivisions,2WN8K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0234 family	yajQ	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
TLS3_k127_6676321_5	1238182.C882_0232	8.057e-108	366.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	chiS	-	2.7.13.3	ko:K07711,ko:K19694	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CBS,GGDEF,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
TLS3_k127_6683627_5	1523503.JPMY01000046_gene1260	5.759e-15	76.0	COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RN7K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
TLS3_k127_6683627_0	404589.Anae109_1587	0.0	1280.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,42YX3@68525|delta/epsilon subdivisions,2WTY2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Phosphoenolpyruvate phosphomutase	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
TLS3_k127_6683627_1	290397.Adeh_2220	2.499e-128	416.0	COG0258@1|root,COG0258@2|Bacteria,1QV40@1224|Proteobacteria,43BZM@68525|delta/epsilon subdivisions,2X7AE@28221|Deltaproteobacteria,2YUE3@29|Myxococcales	28221|Deltaproteobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
TLS3_k127_6683627_3	661478.OP10G_4489	1.288e-38	150.0	2A52F@1|root,30TQU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6683627_4	290397.Adeh_1745	9.528e-38	150.0	COG0716@1|root,COG0716@2|Bacteria,1NANK@1224|Proteobacteria	1224|Proteobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
TLS3_k127_6701247_4	404589.Anae109_0387	9.583e-75	269.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,DnaJ
TLS3_k127_6701247_6	404589.Anae109_0388	6.196e-62	229.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2X2EG@28221|Deltaproteobacteria,2Z20T@29|Myxococcales	28221|Deltaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
TLS3_k127_6701247_0	290397.Adeh_4039	1.85e-111	369.0	COG3804@1|root,COG3804@2|Bacteria,1N3H7@1224|Proteobacteria,433QN@68525|delta/epsilon subdivisions,2WYE0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Dihydrodipicolinate reductase, N-terminus	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
TLS3_k127_6701247_5	290397.Adeh_4038	1.949e-62	218.0	COG2030@1|root,COG2030@2|Bacteria,1RJ2Z@1224|Proteobacteria,4313S@68525|delta/epsilon subdivisions,2WX4Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
TLS3_k127_6701247_2	290397.Adeh_4037	8.658e-80	282.0	COG2030@1|root,COG2030@2|Bacteria,1RD6F@1224|Proteobacteria	1224|Proteobacteria	I	Dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
TLS3_k127_6701247_9	404589.Anae109_0392	1.881e-49	198.0	COG0457@1|root,COG0457@2|Bacteria,1QASR@1224|Proteobacteria,4359Y@68525|delta/epsilon subdivisions,2WZM1@28221|Deltaproteobacteria,2Z2CS@29|Myxococcales	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
TLS3_k127_6701247_1	1379698.RBG1_1C00001G1614	3.614e-89	308.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
TLS3_k127_6701247_7	290397.Adeh_4035	1.898e-52	208.0	COG2834@1|root,COG2834@2|Bacteria,1NMTC@1224|Proteobacteria,42XC3@68525|delta/epsilon subdivisions,2WT97@28221|Deltaproteobacteria,2YWF6@29|Myxococcales	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
TLS3_k127_6701247_3	404589.Anae109_0394	4.507e-79	269.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,42YY2@68525|delta/epsilon subdivisions,2WUI6@28221|Deltaproteobacteria,2Z0E8@29|Myxococcales	28221|Deltaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
TLS3_k127_6701247_8	290397.Adeh_4033	1.238e-50	183.0	COG0848@1|root,COG0848@2|Bacteria,1Q5DA@1224|Proteobacteria,42VMC@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	Biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
TLS3_k127_6723375_2	404589.Anae109_3600	3.157e-32	130.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2WRJJ@28221|Deltaproteobacteria,2YW4G@29|Myxococcales	28221|Deltaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
TLS3_k127_6723375_1	404589.Anae109_2531	1.807e-38	147.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria	1224|Proteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
TLS3_k127_6723375_0	404589.Anae109_2529	1.282e-98	338.0	COG0744@1|root,COG2982@1|root,COG0744@2|Bacteria,COG2982@2|Bacteria,1RDAQ@1224|Proteobacteria,42QW6@68525|delta/epsilon subdivisions,2WPZA@28221|Deltaproteobacteria,2YVC6@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	-	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
TLS3_k127_6837877_5	290397.Adeh_0410	5.706e-54	192.0	COG0642@1|root,COG2205@2|Bacteria,1P4WV@1224|Proteobacteria,43AKH@68525|delta/epsilon subdivisions,2WW5J@28221|Deltaproteobacteria,2YV4B@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_6837877_6	404589.Anae109_4160	1.407e-53	193.0	COG0642@1|root,COG2205@2|Bacteria,1P4WV@1224|Proteobacteria,43AKH@68525|delta/epsilon subdivisions,2WW5J@28221|Deltaproteobacteria,2YV4B@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_6837877_4	404589.Anae109_4159	7.117e-102	351.0	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,42QZ3@68525|delta/epsilon subdivisions,2X5BP@28221|Deltaproteobacteria,2Z2Y4@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_6837877_2	290397.Adeh_0412	3.184e-195	619.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,2YU5T@29|Myxococcales	28221|Deltaproteobacteria	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
TLS3_k127_6837877_0	404589.Anae109_4156	1.585e-275	905.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,2YWE3@29|Myxococcales	28221|Deltaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
TLS3_k127_6837877_1	404589.Anae109_4155	3.298e-250	814.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2YTXZ@29|Myxococcales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
TLS3_k127_6837877_3	404589.Anae109_4154	1.719e-119	393.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria,2YU3N@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TLS3_k127_6881857_7	290397.Adeh_0841	9.928e-34	132.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,42QRY@68525|delta/epsilon subdivisions,2WMW2@28221|Deltaproteobacteria,2YVEE@29|Myxococcales	28221|Deltaproteobacteria	S	YaeQ	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
TLS3_k127_6881857_1	408672.NBCG_01967	3.738e-75	263.0	COG0515@1|root,COG0515@2|Bacteria,2IAFS@201174|Actinobacteria,4DQXW@85009|Propionibacteriales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
TLS3_k127_6881857_2	1187851.A33M_0082	3.143e-64	233.0	COG4122@1|root,COG4122@2|Bacteria,1MU1P@1224|Proteobacteria,2U3B6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
TLS3_k127_6881857_8	251221.35211879	5.082e-33	138.0	2CBAE@1|root,32YK1@2|Bacteria,1G897@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6881857_9	1121861.KB899929_gene296	9.205e-25	108.0	2CBFC@1|root,32RYI@2|Bacteria,1N0T4@1224|Proteobacteria,2UGBM@28211|Alphaproteobacteria,2JUG4@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6881857_6	426117.M446_3155	7.051e-41	158.0	COG2062@1|root,COG2062@2|Bacteria,1RIC8@1224|Proteobacteria,2U9B3@28211|Alphaproteobacteria,1JXYD@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
TLS3_k127_6881857_3	404589.Anae109_1512	5.557e-59	211.0	2CFSQ@1|root,32S2E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6881857_10	543734.LCABL_10820	1.64e-21	109.0	COG0569@1|root,COG0569@2|Bacteria,1UJBH@1239|Firmicutes,4ITNB@91061|Bacilli,3FBX7@33958|Lactobacillaceae	91061|Bacilli	P	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2
TLS3_k127_6881857_0	404589.Anae109_3633	2.455e-137	449.0	COG1215@1|root,COG1215@2|Bacteria,1Q6U2@1224|Proteobacteria,430X8@68525|delta/epsilon subdivisions,2WMWY@28221|Deltaproteobacteria,2Z0V6@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	ugcG	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
TLS3_k127_6881857_4	1278073.MYSTI_05255	5.458e-56	215.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3,Metallophos
TLS3_k127_6881857_5	290397.Adeh_4007	3.104e-54	212.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	oprP	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
TLS3_k127_6912890_0	290397.Adeh_3098	1.064e-240	772.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,4389T@68525|delta/epsilon subdivisions,2X3J6@28221|Deltaproteobacteria,2YWAM@29|Myxococcales	28221|Deltaproteobacteria	E	ERAP1-like C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ERAP1_C,Peptidase_M1
TLS3_k127_6912890_2	1123073.KB899242_gene950	2.559e-78	278.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,1X53Q@135614|Xanthomonadales	135614|Xanthomonadales	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
TLS3_k127_6912890_1	404589.Anae109_1263	3.365e-99	330.0	COG0008@1|root,COG0064@1|root,COG0008@2|Bacteria,COG0064@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2YUA8@29|Myxococcales	28221|Deltaproteobacteria	J	glutaminyl-tRNA	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
TLS3_k127_6922045_8	404589.Anae109_0971	1.642e-132	428.0	COG0003@1|root,COG0003@2|Bacteria,1PMWP@1224|Proteobacteria,42RUR@68525|delta/epsilon subdivisions,2WNEE@28221|Deltaproteobacteria,2YUU4@29|Myxococcales	28221|Deltaproteobacteria	D	AAA domain	agmR	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
TLS3_k127_6922045_11	290397.Adeh_3435	1.193e-32	136.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,HATPase_c,HisKA,Hpt,PAS,Response_reg
TLS3_k127_6922045_4	290397.Adeh_3434	2.761e-189	617.0	COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,2YUST@29|Myxococcales	28221|Deltaproteobacteria	P	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
TLS3_k127_6922045_0	404589.Anae109_0967	5.29e-243	756.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,43DRR@68525|delta/epsilon subdivisions,2X70U@28221|Deltaproteobacteria,2Z3GW@29|Myxococcales	28221|Deltaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metY-1	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
TLS3_k127_6922045_9	653733.Selin_2194	1.047e-57	207.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
TLS3_k127_6922045_3	1416760.AYMS01000040_gene818	1.175e-209	663.0	COG2978@1|root,COG2978@2|Bacteria,4NH64@976|Bacteroidetes,1I0S9@117743|Flavobacteriia	976|Bacteroidetes	H	AbgT putative transporter family	ydaH	-	-	ko:K12942	-	-	-	-	ko00000	-	-	-	ABG_transport
TLS3_k127_6922045_7	404589.Anae109_2356	1.463e-149	505.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2X7XX@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
TLS3_k127_6922045_5	404589.Anae109_2487	7.611e-162	538.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,2YWJD@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_6922045_6	290397.Adeh_0923	5.623e-154	497.0	COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,42YZ2@68525|delta/epsilon subdivisions,2WTQ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02668,ko:K07709	ko02020,map02020	M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_10,PAS_4,PAS_9,sCache_3_2
TLS3_k127_6922045_2	290397.Adeh_0922	9.65e-211	687.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_6922045_10	404589.Anae109_0956	2.494e-49	183.0	COG3005@1|root,COG3005@2|Bacteria,1N0I4@1224|Proteobacteria,42R1B@68525|delta/epsilon subdivisions,2WSF5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	cytochrome c	-	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
TLS3_k127_6922045_1	404589.Anae109_0955	8.549e-232	736.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,42MPU@68525|delta/epsilon subdivisions,2WIJ1@28221|Deltaproteobacteria,2YUSH@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
TLS3_k127_693183_3	1129374.AJE_07171	1.045e-21	107.0	COG1216@1|root,COG1216@2|Bacteria,1REI6@1224|Proteobacteria,1S66Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_693183_0	404589.Anae109_1631	8.966e-300	930.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2YUEB@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase components of ABC transporters with duplicated ATPase domains	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_693183_1	290397.Adeh_0311	7.479e-99	327.0	COG0421@1|root,COG0421@2|Bacteria,1QUUH@1224|Proteobacteria,42MJV@68525|delta/epsilon subdivisions,2WMKH@28221|Deltaproteobacteria,2YV71@29|Myxococcales	28221|Deltaproteobacteria	E	Pfam:Methyltransf_26	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
TLS3_k127_693183_2	404589.Anae109_1734	4.73e-69	235.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,42UVY@68525|delta/epsilon subdivisions,2WR44@28221|Deltaproteobacteria,2YVAT@29|Myxococcales	28221|Deltaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
TLS3_k127_6952756_3	246197.MXAN_3419	2.692e-18	94.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,4301R@68525|delta/epsilon subdivisions,2WVCA@28221|Deltaproteobacteria,2YYZK@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_6952756_0	1242864.D187_007813	3.323e-188	599.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
TLS3_k127_6952756_2	378806.STAUR_8052	3.958e-24	107.0	2EV1C@1|root,33NGG@2|Bacteria,1NKKY@1224|Proteobacteria,42X6Y@68525|delta/epsilon subdivisions,2WTH7@28221|Deltaproteobacteria,2Z0VE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6952756_1	290397.Adeh_2905	1.243e-110	366.0	COG0671@1|root,COG0671@2|Bacteria,1RDK3@1224|Proteobacteria,42TCF@68525|delta/epsilon subdivisions,2WPUS@28221|Deltaproteobacteria,2YVXS@29|Myxococcales	28221|Deltaproteobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
TLS3_k127_6975118_2	290397.Adeh_0109	1.473e-186	599.0	COG2864@1|root,COG3005@1|root,COG2864@2|Bacteria,COG3005@2|Bacteria,1NJEJ@1224|Proteobacteria,42NQM@68525|delta/epsilon subdivisions,2WK76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
TLS3_k127_6975118_1	404589.Anae109_0117	1.546e-203	640.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2YTUE@29|Myxococcales	28221|Deltaproteobacteria	D	Rod shape-determining protein	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
TLS3_k127_6975118_0	290397.Adeh_0114	5.388e-257	809.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,432ME@68525|delta/epsilon subdivisions,2WYJH@28221|Deltaproteobacteria,2Z1S7@29|Myxococcales	28221|Deltaproteobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
TLS3_k127_6975118_3	404589.Anae109_0120	1.583e-69	243.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,42SCQ@68525|delta/epsilon subdivisions,2WPZQ@28221|Deltaproteobacteria,2YX0Q@29|Myxococcales	28221|Deltaproteobacteria	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
TLS3_k127_6975118_5	290397.Adeh_0117	3.256e-49	177.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,42VJQ@68525|delta/epsilon subdivisions,2WR7Z@28221|Deltaproteobacteria,2YVPB@29|Myxococcales	28221|Deltaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
TLS3_k127_6975118_4	404589.Anae109_0122	5.76e-63	219.0	COG0360@1|root,COG0360@2|Bacteria	2|Bacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	4.3.1.19	ko:K01754,ko:K02990	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,ko03010,map00260,map00290,map01100,map01110,map01130,map01200,map01230,map03010	M00178,M00570	R00220,R00996	RC00418,RC02600	br01610,ko00000,ko00001,ko00002,ko01000,ko03011,ko03029	-	-	-	Ribosomal_S6
TLS3_k127_6985522_2	290397.Adeh_0403	4.736e-172	546.0	COG5459@1|root,COG5459@2|Bacteria,1MWMM@1224|Proteobacteria,42WIB@68525|delta/epsilon subdivisions,2WRHR@28221|Deltaproteobacteria,2Z341@29|Myxococcales	28221|Deltaproteobacteria	J	Mitochondrial small ribosomal subunit Rsm22	-	-	-	-	-	-	-	-	-	-	-	-	Rsm22
TLS3_k127_6985522_3	404589.Anae109_4166	3.744e-160	510.0	COG4586@1|root,COG4586@2|Bacteria,1RA7G@1224|Proteobacteria,42RT3@68525|delta/epsilon subdivisions,2WNGM@28221|Deltaproteobacteria,2YU3C@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_6985522_4	404589.Anae109_4165	6.428e-150	480.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
TLS3_k127_6985522_6	404589.Anae109_4164	4.83e-48	179.0	COG3945@1|root,COG3945@2|Bacteria	2|Bacteria	P	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
TLS3_k127_6985522_1	290397.Adeh_0407	2.983e-220	689.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42N7F@68525|delta/epsilon subdivisions,2WJB2@28221|Deltaproteobacteria,2YUH3@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	fadI	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
TLS3_k127_6985522_0	404589.Anae109_4162	0.0	1054.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2WINP@28221|Deltaproteobacteria,2YU7W@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
TLS3_k127_6985522_5	404589.Anae109_1257	1.735e-62	243.0	COG3303@1|root,COG3303@2|Bacteria,1R8WP@1224|Proteobacteria,42VEM@68525|delta/epsilon subdivisions,2WRGV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6993279_4	290397.Adeh_1293	1.082e-52	190.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,42V77@68525|delta/epsilon subdivisions,2WRQF@28221|Deltaproteobacteria,2YVTX@29|Myxococcales	28221|Deltaproteobacteria	K	FR47-like protein	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
TLS3_k127_6993279_1	404589.Anae109_2474	3.626e-151	483.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria,2YWFP@29|Myxococcales	28221|Deltaproteobacteria	O	DnaJ C terminal domain	-	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
TLS3_k127_6993279_3	404589.Anae109_2475	2.321e-95	319.0	COG1413@1|root,COG1413@2|Bacteria,1PC2V@1224|Proteobacteria,4387S@68525|delta/epsilon subdivisions,2X3HJ@28221|Deltaproteobacteria,2YW4Z@29|Myxococcales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
TLS3_k127_6993279_0	290397.Adeh_1289	4.421e-283	893.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2Z2SY@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TLS3_k127_6993279_2	290397.Adeh_1288	3.551e-99	330.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MB6@68525|delta/epsilon subdivisions,2WJMI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	ato-2	-	2.8.3.18,3.1.2.1	ko:K01067,ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00227,R10343	RC00004,RC00012,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1125	AcetylCoA_hyd_C,AcetylCoA_hydro
TLS3_k127_7053258_13	290397.Adeh_0145	8.385e-36	136.0	COG0618@1|root,COG0618@2|Bacteria,1MX0B@1224|Proteobacteria,42P48@68525|delta/epsilon subdivisions,2WIUR@28221|Deltaproteobacteria,2Z3E8@29|Myxococcales	28221|Deltaproteobacteria	S	3'(2'),5'-bisphosphate nucleotidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7053258_12	290397.Adeh_0144	1.577e-68	238.0	COG0745@1|root,COG0745@2|Bacteria	290397.Adeh_0144|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7053258_9	290397.Adeh_0143	4.656e-108	360.0	COG2129@1|root,COG2129@2|Bacteria,1MVNK@1224|Proteobacteria,43077@68525|delta/epsilon subdivisions,2WVAJ@28221|Deltaproteobacteria,2YUHT@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
TLS3_k127_7053258_10	290397.Adeh_0142	2.992e-86	311.0	COG4914@1|root,COG4914@2|Bacteria,1QX3W@1224|Proteobacteria,43BWC@68525|delta/epsilon subdivisions,2X774@28221|Deltaproteobacteria,2YYN5@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204,NTP_transf_5
TLS3_k127_7053258_5	290397.Adeh_0141	5.871e-159	515.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2YU4K@29|Myxococcales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
TLS3_k127_7053258_11	404589.Anae109_0144	8.089e-69	240.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	MA20_09445	-	-	ko:K09017,ko:K18301	-	M00642	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	TetR_C_11,TetR_N
TLS3_k127_7053258_4	404589.Anae109_0143	8.479e-162	531.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,42REB@68525|delta/epsilon subdivisions,2WNWD@28221|Deltaproteobacteria,2YUH8@29|Myxococcales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
TLS3_k127_7053258_6	290397.Adeh_0138	2.417e-112	371.0	COG0846@1|root,COG0846@2|Bacteria	2|Bacteria	K	NAD+ binding	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
TLS3_k127_7053258_3	404589.Anae109_2847	2.002e-166	532.0	COG0823@1|root,COG0823@2|Bacteria,1QW3I@1224|Proteobacteria,42YA5@68525|delta/epsilon subdivisions,2WU6I@28221|Deltaproteobacteria,2Z3J0@29|Myxococcales	28221|Deltaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_7053258_7	290397.Adeh_0137	2.944e-111	373.0	COG0457@1|root,COG3824@1|root,COG0457@2|Bacteria,COG3824@2|Bacteria	2|Bacteria	S	Zincin-like metallopeptidase	MA20_43655	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Zincin_1
TLS3_k127_7053258_0	290397.Adeh_0135	9.676e-215	676.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2YU1G@29|Myxococcales	28221|Deltaproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
TLS3_k127_7053258_1	404589.Anae109_0138	1.392e-181	572.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2WKT8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
TLS3_k127_7053258_2	404589.Anae109_0137	1.462e-168	537.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WNXT@28221|Deltaproteobacteria,2YV4W@29|Myxococcales	28221|Deltaproteobacteria	EGP	of the major facilitator superfamily	agmP	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,Sugar_tr
TLS3_k127_7053258_8	290397.Adeh_0131	3.83e-109	359.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,42N8E@68525|delta/epsilon subdivisions,2WIY0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
TLS3_k127_7064972_3	290397.Adeh_3475	7.405e-28	114.0	COG1181@1|root,COG1181@2|Bacteria,1QXU6@1224|Proteobacteria,43C6Q@68525|delta/epsilon subdivisions,2X7NN@28221|Deltaproteobacteria,2Z3H4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7064972_2	290397.Adeh_3473	1.438e-138	447.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M4Q@68525|delta/epsilon subdivisions,2X5DU@28221|Deltaproteobacteria,2YVAA@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0069	GGDEF,Response_reg
TLS3_k127_7064972_1	290397.Adeh_3472	3.019e-198	632.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42N5C@68525|delta/epsilon subdivisions,2WM18@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
TLS3_k127_7064972_0	404589.Anae109_3581	4.047e-267	827.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJF9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_7089610_1	404589.Anae109_0661	5.893e-128	413.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,2YUPW@29|Myxococcales	28221|Deltaproteobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
TLS3_k127_7089610_0	404589.Anae109_0662	1.661e-159	529.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,42PCD@68525|delta/epsilon subdivisions,2WKGQ@28221|Deltaproteobacteria,2YU9M@29|Myxococcales	28221|Deltaproteobacteria	F	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
TLS3_k127_7089610_4	290397.Adeh_0618	7.176e-108	377.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,42P3C@68525|delta/epsilon subdivisions,2X21N@28221|Deltaproteobacteria,2Z2ZB@29|Myxococcales	28221|Deltaproteobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
TLS3_k127_7089610_6	290397.Adeh_0620	2.118e-50	182.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,42UZH@68525|delta/epsilon subdivisions,2WR2R@28221|Deltaproteobacteria,2YVFS@29|Myxococcales	28221|Deltaproteobacteria	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
TLS3_k127_7089610_2	404589.Anae109_0666	1.024e-119	397.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2WJTU@28221|Deltaproteobacteria,2YV5E@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
TLS3_k127_7089610_3	290397.Adeh_0622	3.253e-115	375.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2YTYC@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
TLS3_k127_7182716_2	404589.Anae109_0698	3.064e-42	166.0	COG2911@1|root,COG2911@2|Bacteria,1PQTA@1224|Proteobacteria,42PYT@68525|delta/epsilon subdivisions,2WIZ6@28221|Deltaproteobacteria,2YVF0@29|Myxococcales	28221|Deltaproteobacteria	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
TLS3_k127_7182716_0	290397.Adeh_0651	6.739e-202	654.0	COG0457@1|root,COG0457@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
TLS3_k127_7182716_1	290397.Adeh_0650	3.518e-55	196.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2YUJ1@29|Myxococcales	28221|Deltaproteobacteria	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.1,6.4.1.2	ko:K01959,ko:K01961	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376,M00620	R00344,R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
TLS3_k127_7191971_2	404589.Anae109_1956	9.884e-24	110.0	COG0484@1|root,COG1426@1|root,COG0484@2|Bacteria,COG1426@2|Bacteria	2|Bacteria	S	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,HTH_25,TPR_14
TLS3_k127_7191971_1	404589.Anae109_1954	4.461e-108	351.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,437B2@68525|delta/epsilon subdivisions,2X2FR@28221|Deltaproteobacteria,2Z0QW@29|Myxococcales	28221|Deltaproteobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
TLS3_k127_7191971_0	290397.Adeh_1906	1.993e-166	544.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WPM9@28221|Deltaproteobacteria,2YV6T@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	mltE	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_19,TPR_6,TPR_8
TLS3_k127_7195760_4	290397.Adeh_0952	1.153e-63	237.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,42RPS@68525|delta/epsilon subdivisions,2WPH5@28221|Deltaproteobacteria,2Z0ZS@29|Myxococcales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
TLS3_k127_7195760_5	290397.Adeh_0951	3.798e-51	187.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
TLS3_k127_7195760_7	1278073.MYSTI_00081	4.075e-32	131.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM5Q@28221|Deltaproteobacteria,2YX39@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_8,PAS_9,Response_reg
TLS3_k127_7195760_3	404589.Anae109_0990	5.581e-143	493.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42PT2@68525|delta/epsilon subdivisions,2WJ6Q@28221|Deltaproteobacteria,2YWF8@29|Myxococcales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
TLS3_k127_7195760_2	404589.Anae109_0988	1.307e-162	545.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,42P67@68525|delta/epsilon subdivisions,2WJP7@28221|Deltaproteobacteria,2Z34G@29|Myxococcales	28221|Deltaproteobacteria	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
TLS3_k127_7195760_6	290397.Adeh_0947	5.526e-33	138.0	COG1371@1|root,COG1371@2|Bacteria	2|Bacteria	J	PFAM Archease protein family (DUF101 UPF0211)	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Archease
TLS3_k127_7195760_1	290397.Adeh_0946	1.837e-245	764.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
TLS3_k127_7195760_9	565653.EGBG_01049	0.00055	46.0	COG3237@1|root,COG3237@2|Bacteria,1VM8P@1239|Firmicutes,4IJ4W@91061|Bacilli,4B4GI@81852|Enterococcaceae	91061|Bacilli	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
TLS3_k127_7195760_0	404589.Anae109_0984	2.066e-309	964.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2WJ7Y@28221|Deltaproteobacteria,2YX41@29|Myxococcales	28221|Deltaproteobacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
TLS3_k127_7195760_8	290397.Adeh_0938	1.437e-19	104.0	2E3Q4@1|root,32YN3@2|Bacteria,1PXPZ@1224|Proteobacteria,434RA@68525|delta/epsilon subdivisions,2X8ZN@28221|Deltaproteobacteria,2Z16H@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7197207_5	290397.Adeh_3788	7.261e-33	131.0	COG0577@1|root,COG0577@2|Bacteria,1QXV8@1224|Proteobacteria,43C7Z@68525|delta/epsilon subdivisions,2X7IB@28221|Deltaproteobacteria,2YUZK@29|Myxococcales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
TLS3_k127_7197207_4	290397.Adeh_3787	4.479e-65	249.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42SHB@68525|delta/epsilon subdivisions,2WUKC@28221|Deltaproteobacteria,2YV2F@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_7197207_3	404589.Anae109_3907	6.385e-74	277.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,42M78@68525|delta/epsilon subdivisions,2WRKW@28221|Deltaproteobacteria,2YVUK@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
TLS3_k127_7197207_0	404589.Anae109_3904	0.0	1405.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2YU3X@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
TLS3_k127_7197207_1	290397.Adeh_0299	4.767e-95	320.0	COG4097@1|root,COG4097@2|Bacteria,1MV9P@1224|Proteobacteria,42QJV@68525|delta/epsilon subdivisions,2WK93@28221|Deltaproteobacteria,2YZ62@29|Myxococcales	28221|Deltaproteobacteria	C	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
TLS3_k127_7255982_2	404589.Anae109_3350	5.609e-166	531.0	COG0515@1|root,COG0589@1|root,COG0515@2|Bacteria,COG0589@2|Bacteria,1MV1P@1224|Proteobacteria,42VSC@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Protein tyrosine kinase	MA20_09295	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Usp
TLS3_k127_7255982_0	404589.Anae109_3354	6.585e-173	577.0	COG4585@1|root,COG4585@2|Bacteria,1RBN9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
TLS3_k127_7255982_3	404589.Anae109_3355	5.541e-62	235.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria	1224|Proteobacteria	K	response regulator	-	-	-	ko:K07685	ko02020,map02020	M00472	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
TLS3_k127_7255982_4	243231.GSU2326	1.408e-52	190.0	COG3040@1|root,COG3040@2|Bacteria,1RIHP@1224|Proteobacteria,42SSW@68525|delta/epsilon subdivisions,2X6M9@28221|Deltaproteobacteria,43VBP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
TLS3_k127_7255982_1	1121377.KB906401_gene3384	8.426e-171	569.0	COG3903@1|root,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,DUF4062,GerE,NB-ARC,TPR_12
TLS3_k127_7255982_5	1192034.CAP_1661	0.0002127	46.0	COG0784@1|root,COG0784@2|Bacteria,1QAM7@1224|Proteobacteria,43563@68525|delta/epsilon subdivisions,2WZH3@28221|Deltaproteobacteria,2Z24X@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
TLS3_k127_7266566_3	448385.sce6976	1.469e-54	208.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	-	-	-	ko:K01932,ko:K03301	-	-	-	-	ko00000,ko01000	2.A.12	-	-	Glyco_transf_4,Glycos_transf_1,HEAT_2,TLC
TLS3_k127_7266566_1	378806.STAUR_7238	1.979e-96	339.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
TLS3_k127_7266566_4	404589.Anae109_3526	8.364e-33	140.0	COG1977@1|root,COG1977@2|Bacteria,1N6RG@1224|Proteobacteria,43BB8@68525|delta/epsilon subdivisions,2X6QE@28221|Deltaproteobacteria,2YVUR@29|Myxococcales	28221|Deltaproteobacteria	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
TLS3_k127_7266566_0	404589.Anae109_3525	4.224e-174	552.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,432XE@68525|delta/epsilon subdivisions,2WYHS@28221|Deltaproteobacteria,2YU0E@29|Myxococcales	28221|Deltaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7266566_2	1121920.AUAU01000019_gene2583	1.098e-60	222.0	2E0YU@1|root,32WF9@2|Bacteria,3Y7YV@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
TLS3_k127_7266566_5	693977.Deipr_2575	3.373e-06	51.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
TLS3_k127_7267174_2	404589.Anae109_2752	7.299e-27	116.0	COG2703@1|root,COG2703@2|Bacteria	2|Bacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Guanylate_cyc,Hemerythrin
TLS3_k127_7267174_4	456442.Mboo_0454	2.15e-15	83.0	COG2703@1|root,arCOG06577@2157|Archaea,2Y1Y0@28890|Euryarchaeota,2NB26@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
TLS3_k127_7267174_3	404589.Anae109_0575	2.054e-22	108.0	COG3047@1|root,COG3047@2|Bacteria,1QAKM@1224|Proteobacteria,4355Q@68525|delta/epsilon subdivisions,2WZGM@28221|Deltaproteobacteria,2Z23W@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7267174_1	404589.Anae109_4140	1.098e-127	414.0	COG1801@1|root,COG1801@2|Bacteria,1N4QE@1224|Proteobacteria,42PDW@68525|delta/epsilon subdivisions,2WK6H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
TLS3_k127_7267174_0	290397.Adeh_2814	2.072e-144	461.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,42PTC@68525|delta/epsilon subdivisions,2WM3S@28221|Deltaproteobacteria,2YTUU@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
TLS3_k127_7334873_12	378806.STAUR_3635	6.265e-12	65.0	COG1734@1|root,COG1734@2|Bacteria,1N8RB@1224|Proteobacteria,42W5H@68525|delta/epsilon subdivisions,2WSAD@28221|Deltaproteobacteria,2YVJ6@29|Myxococcales	28221|Deltaproteobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
TLS3_k127_7334873_9	290397.Adeh_2553	1.249e-44	173.0	COG1716@1|root,COG1716@2|Bacteria,1Q2GC@1224|Proteobacteria,4382T@68525|delta/epsilon subdivisions,2X0C6@28221|Deltaproteobacteria,2YVG7@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
TLS3_k127_7334873_0	290397.Adeh_2550	0.0	1150.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,2YUFJ@29|Myxococcales	28221|Deltaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
TLS3_k127_7334873_13	1008457.BAEX01000098_gene2229	5.471e-11	70.0	2DMHT@1|root,32RN3@2|Bacteria,4NPZK@976|Bacteroidetes,1I2PC@117743|Flavobacteriia,47J1W@76831|Myroides	976|Bacteroidetes	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
TLS3_k127_7334873_10	404589.Anae109_1312	2.507e-43	163.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,42TSD@68525|delta/epsilon subdivisions,2WQ6E@28221|Deltaproteobacteria,2YVDZ@29|Myxococcales	28221|Deltaproteobacteria	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
TLS3_k127_7334873_1	404589.Anae109_1315	1.305e-224	700.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,42MNR@68525|delta/epsilon subdivisions,2WJ70@28221|Deltaproteobacteria,2YU37@29|Myxococcales	28221|Deltaproteobacteria	C	lysine 2,3-aminomutase	kamA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
TLS3_k127_7334873_3	404589.Anae109_1316	3.908e-174	556.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,42MNR@68525|delta/epsilon subdivisions,2WJ70@28221|Deltaproteobacteria,2YU37@29|Myxococcales	28221|Deltaproteobacteria	C	lysine 2,3-aminomutase	kamA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
TLS3_k127_7334873_7	290397.Adeh_2545	3.346e-73	274.0	COG2385@1|root,COG2385@2|Bacteria,1RGJS@1224|Proteobacteria,42RZE@68525|delta/epsilon subdivisions,2WNH8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Stage II sporulation D domain protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
TLS3_k127_7334873_6	290397.Adeh_2544	2.036e-134	436.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,42MMG@68525|delta/epsilon subdivisions,2WJ9W@28221|Deltaproteobacteria,2YUD8@29|Myxococcales	28221|Deltaproteobacteria	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
TLS3_k127_7334873_2	404589.Anae109_1321	6.051e-191	604.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria,2YU84@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
TLS3_k127_7334873_11	290397.Adeh_2541	4.595e-35	139.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,42V1U@68525|delta/epsilon subdivisions,2WR76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	TIGRFAM preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
TLS3_k127_7334873_5	483219.LILAB_31400	5.146e-135	451.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2YU0A@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
TLS3_k127_7334873_4	404589.Anae109_1324	7.309e-171	577.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,2YUZD@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
TLS3_k127_7353703_0	1192034.CAP_8124	0.0	1412.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2YUB0@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
TLS3_k127_7353703_6	404589.Anae109_4263	9.035e-94	344.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,2YZUC@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23
TLS3_k127_7353703_11	305700.B447_14684	1.916e-11	77.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,2VMAB@28216|Betaproteobacteria,2KUNJ@206389|Rhodocyclales	206389|Rhodocyclales	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_7353703_3	404589.Anae109_4258	2.939e-167	563.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,4301R@68525|delta/epsilon subdivisions,2WVCA@28221|Deltaproteobacteria,2YYZK@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_7353703_2	290397.Adeh_0302	5.015e-199	654.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YY7A@29|Myxococcales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_7353703_9	290397.Adeh_1488	2.231e-35	150.0	COG0776@1|root,COG0776@2|Bacteria,1NM9X@1224|Proteobacteria,42TZ5@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	Belongs to the bacterial histone-like protein family	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
TLS3_k127_7353703_4	404589.Anae109_2345	7.208e-133	437.0	COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,42QYC@68525|delta/epsilon subdivisions,2WN66@28221|Deltaproteobacteria,2Z2W3@29|Myxococcales	28221|Deltaproteobacteria	S	Pfam:Kce	-	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	4HBT,BKACE
TLS3_k127_7353703_7	290397.Adeh_1486	2.579e-62	229.0	COG1607@1|root,COG1607@2|Bacteria,1RJNJ@1224|Proteobacteria	1224|Proteobacteria	I	Thioesterase superfamily	-	-	4.3.1.14	ko:K18014	ko00310,map00310	-	R03030	RC00833	ko00000,ko00001,ko01000	-	-	-	4HBT
TLS3_k127_7353703_5	290397.Adeh_1485	4.984e-120	394.0	COG5012@1|root,COG5012@2|Bacteria,1QYG0@1224|Proteobacteria,43CC4@68525|delta/epsilon subdivisions,2X7MZ@28221|Deltaproteobacteria,2Z3GZ@29|Myxococcales	28221|Deltaproteobacteria	S	Dimerisation domain of d-ornithine 4,5-aminomutase	-	-	5.4.3.3	ko:K18011	ko00310,map00310	-	R02852,R03275	RC00719	ko00000,ko00001,ko01000	-	-	-	B12-binding,OAM_dimer
TLS3_k127_7353703_1	404589.Anae109_2349	1.424e-261	813.0	COG0274@1|root,COG0274@2|Bacteria,1R45J@1224|Proteobacteria,438PK@68525|delta/epsilon subdivisions,2X8TQ@28221|Deltaproteobacteria,2YXFJ@29|Myxococcales	28221|Deltaproteobacteria	F	D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit	kamD	-	5.4.3.3	ko:K01844	ko00310,map00310	-	R02852,R03275	RC00719	ko00000,ko00001,ko01000	-	-	-	Lys-AminoMut_A
TLS3_k127_7357345_3	290397.Adeh_0046	2.247e-26	113.0	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,42P08@68525|delta/epsilon subdivisions,2WJXV@28221|Deltaproteobacteria,2YYSQ@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
TLS3_k127_7357345_2	502025.Hoch_2011	1.649e-38	151.0	2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,42TQF@68525|delta/epsilon subdivisions,2WQHJ@28221|Deltaproteobacteria,2Z109@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3015
TLS3_k127_7357345_1	290397.Adeh_1129	5.453e-90	323.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
TLS3_k127_7357345_0	290397.Adeh_1128	2.241e-94	320.0	COG0697@1|root,COG0697@2|Bacteria,1MX1Y@1224|Proteobacteria,42NTW@68525|delta/epsilon subdivisions,2WMEN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_7379548_1	404589.Anae109_2544	1.628e-236	744.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42Q0K@68525|delta/epsilon subdivisions,2WJUW@28221|Deltaproteobacteria,2YTVH@29|Myxococcales	28221|Deltaproteobacteria	L	DbpA RNA binding domain	dedA	-	3.6.4.13	ko:K03732,ko:K05592	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
TLS3_k127_7379548_3	290397.Adeh_1224	8.715e-149	477.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,2YU1B@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03086,ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS3_k127_7379548_5	290397.Adeh_1222	4.256e-111	376.0	COG1657@1|root,COG1657@2|Bacteria,1QX5U@1224|Proteobacteria,42ZX1@68525|delta/epsilon subdivisions,2WVF4@28221|Deltaproteobacteria,2YV56@29|Myxococcales	28221|Deltaproteobacteria	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
TLS3_k127_7379548_0	290397.Adeh_1221	2.791e-287	913.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1MVWA@1224|Proteobacteria,42ZBA@68525|delta/epsilon subdivisions,2WUF4@28221|Deltaproteobacteria,2YUZP@29|Myxococcales	28221|Deltaproteobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
TLS3_k127_7379548_8	290397.Adeh_1220	1.959e-44	166.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,42MCS@68525|delta/epsilon subdivisions,2WRZW@28221|Deltaproteobacteria,2YWS5@29|Myxococcales	28221|Deltaproteobacteria	O	Peptidyl-prolyl cis-trans	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
TLS3_k127_7379548_6	404589.Anae109_2552	3.682e-101	351.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions	1224|Proteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100,1.1.1.159,1.1.1.173,1.1.1.304,1.1.1.377,1.1.1.378,1.1.1.76,1.3.1.28	ko:K00059,ko:K00076,ko:K00216,ko:K03366,ko:K13774,ko:K18337	ko00051,ko00061,ko00121,ko00281,ko00333,ko00650,ko00780,ko01040,ko01053,ko01100,ko01110,ko01120,ko01130,ko01212,map00051,map00061,map00121,map00281,map00333,map00650,map00780,map01040,map01053,map01100,map01110,map01120,map01130,map01212	M00083,M00572	R01505,R02855,R02946,R03707,R03942,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R08087,R08096,R09078,R10116,R10120,R10125,R10126,R10505,R10788,R10995,R11671	RC00029,RC00066,RC00080,RC00087,RC00117,RC00161,RC00205,RC00525,RC00534	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
TLS3_k127_7379548_4	290397.Adeh_1218	1.966e-134	435.0	COG0546@1|root,COG0546@2|Bacteria,1QX7M@1224|Proteobacteria,438Y4@68525|delta/epsilon subdivisions,2X43J@28221|Deltaproteobacteria,2YY61@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
TLS3_k127_7379548_7	631454.N177_2306	8.231e-45	173.0	COG1225@1|root,COG1225@2|Bacteria,1N47I@1224|Proteobacteria,2UK40@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Iodothyronine deiodinase	-	-	-	-	-	-	-	-	-	-	-	-	T4_deiodinase
TLS3_k127_7379548_9	404589.Anae109_2553	7.983e-43	159.0	COG3411@1|root,COG3411@2|Bacteria,1RM68@1224|Proteobacteria,42TUK@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7379548_2	290397.Adeh_2359	7.166e-165	529.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
TLS3_k127_7389827_3	404589.Anae109_0830	9.059e-29	125.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,42N18@68525|delta/epsilon subdivisions,2WJSK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2766	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS3_k127_7389827_0	290397.Adeh_0781	0.0	1235.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,42NY6@68525|delta/epsilon subdivisions,2WJSE@28221|Deltaproteobacteria,2YU0W@29|Myxococcales	28221|Deltaproteobacteria	C	dehydrogenase, E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
TLS3_k127_7389827_2	404589.Anae109_0827	4.126e-84	293.0	COG0778@1|root,COG0778@2|Bacteria,1NTK9@1224|Proteobacteria,435C9@68525|delta/epsilon subdivisions,2WZPV@28221|Deltaproteobacteria,2Z2HG@29|Myxococcales	28221|Deltaproteobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7389827_1	290397.Adeh_0778	9.033e-155	506.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WKVE@28221|Deltaproteobacteria,2YV07@29|Myxococcales	28221|Deltaproteobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
TLS3_k127_7389827_4	290397.Adeh_0774	6.44e-05	49.0	COG2214@1|root,COG2214@2|Bacteria,1ND5S@1224|Proteobacteria,42XS8@68525|delta/epsilon subdivisions,2WSUV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7420806_2	404589.Anae109_4415	1.9e-103	341.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42NUE@68525|delta/epsilon subdivisions,2WMSB@28221|Deltaproteobacteria,2Z33U@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
TLS3_k127_7420806_0	290397.Adeh_4259	9.485e-125	420.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42M19@68525|delta/epsilon subdivisions,2WIYH@28221|Deltaproteobacteria,2YUXC@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
TLS3_k127_7420806_1	404589.Anae109_4413	1.085e-108	374.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42NMG@68525|delta/epsilon subdivisions,2WJIS@28221|Deltaproteobacteria,2YWX6@29|Myxococcales	28221|Deltaproteobacteria	E	amino acid ABC transporter, ATP-binding protein	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
TLS3_k127_7476859_4	378806.STAUR_6997	2.417e-100	335.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42NN9@68525|delta/epsilon subdivisions,2WM5V@28221|Deltaproteobacteria,2Z32B@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase Ligase (LigD)	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
TLS3_k127_7476859_7	290397.Adeh_0958	6.04e-25	116.0	2E8MZ@1|root,332ZD@2|Bacteria,1P763@1224|Proteobacteria,432M3@68525|delta/epsilon subdivisions,2WXF5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7476859_6	404589.Anae109_1009	4.207e-30	125.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	btrV	-	2.4.1.187,2.7.11.1	ko:K02066,ko:K02660,ko:K04749,ko:K04757,ko:K05946,ko:K06378	ko02010,ko02020,ko02025,ko05111,map02010,map02020,map02025,map05111	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01003,ko02000,ko02035,ko02044,ko03021	3.A.1.27	GT26	-	APH,STAS,STAS_2
TLS3_k127_7476859_8	290397.Adeh_2082	1.725e-15	85.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
TLS3_k127_7476859_3	290397.Adeh_2083	1.324e-126	427.0	COG2982@1|root,COG2982@2|Bacteria,1PJZH@1224|Proteobacteria	1224|Proteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
TLS3_k127_7476859_5	290397.Adeh_2795	1.059e-43	165.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	1.3.7.14,1.3.7.15	ko:K03088,ko:K11333	ko00860,ko01110,map00860,map01110	-	R09053,R09060	RC01008	ko00000,ko00001,ko01000,ko03021	-	-	-	Fer4_NifH,Glyco_hydro_cc,Laminin_G_3,Sigma70_r2,Sigma70_r4_2
TLS3_k127_7476859_1	404589.Anae109_1549	7.273e-149	507.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,1MV1P@1224|Proteobacteria,42PPB@68525|delta/epsilon subdivisions,2X5YN@28221|Deltaproteobacteria,2YUEJ@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12
TLS3_k127_7476859_0	290397.Adeh_0298	0.0	1052.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42PZF@68525|delta/epsilon subdivisions,2X5HR@28221|Deltaproteobacteria,2YYCV@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_7476859_2	290397.Adeh_0965	1.28e-146	467.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2YW0C@29|Myxococcales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
TLS3_k127_7478276_3	404589.Anae109_4455	6.937e-81	280.0	COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,42TN7@68525|delta/epsilon subdivisions,2WQK7@28221|Deltaproteobacteria,2Z366@29|Myxococcales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
TLS3_k127_7478276_4	404589.Anae109_4225	1.145e-62	242.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	BRCT,DUF433,HTH_17,MerR_1,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
TLS3_k127_7478276_1	404589.Anae109_4457	3.528e-160	531.0	COG4191@1|root,COG4191@2|Bacteria,1R9SH@1224|Proteobacteria,42QAE@68525|delta/epsilon subdivisions,2WM61@28221|Deltaproteobacteria,2Z2WP@29|Myxococcales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,dCache_1
TLS3_k127_7478276_2	290397.Adeh_4313	7.062e-85	286.0	COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,42MHQ@68525|delta/epsilon subdivisions,2WJAC@28221|Deltaproteobacteria,2YUS7@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
TLS3_k127_7505732_0	1254432.SCE1572_14255	1.305e-137	447.0	COG2978@1|root,COG2978@2|Bacteria,1MUJ1@1224|Proteobacteria,42N8Z@68525|delta/epsilon subdivisions,2WTR2@28221|Deltaproteobacteria,2YU56@29|Myxococcales	28221|Deltaproteobacteria	H	AbgT putative transporter family	abgT	-	-	ko:K12942	-	-	-	-	ko00000	-	-	-	ABG_transport
TLS3_k127_7505732_4	1150621.SMUL_2892	2.962e-16	82.0	COG3585@1|root,COG3585@2|Bacteria,1P6UA@1224|Proteobacteria,432HS@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	TOBE
TLS3_k127_7505732_1	404589.Anae109_3735	3.562e-91	305.0	COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,42RHH@68525|delta/epsilon subdivisions,2WNVX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	LrgB-like family	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
TLS3_k127_7505732_3	404589.Anae109_3734	2.134e-35	142.0	COG1380@1|root,COG1380@2|Bacteria,1N753@1224|Proteobacteria,42VF9@68525|delta/epsilon subdivisions,2WT6C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	LrgA family	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
TLS3_k127_7505732_2	290397.Adeh_3999	1.925e-47	174.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42SI3@68525|delta/epsilon subdivisions,2WPVX@28221|Deltaproteobacteria,2YXH0@29|Myxococcales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
TLS3_k127_7558722_1	215803.DB30_1694	4.289e-186	591.0	COG2182@1|root,COG2182@2|Bacteria,1N9AE@1224|Proteobacteria,43EXV@68525|delta/epsilon subdivisions,2X9AJ@28221|Deltaproteobacteria,2YZDJ@29|Myxococcales	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10108,ko:K15770	ko02010,ko02030,map02010,map02030	M00194,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22	-	-	SBP_bac_1
TLS3_k127_7558722_2	290397.Adeh_4137	5.852e-160	512.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42NVJ@68525|delta/epsilon subdivisions,2WJN1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.20	ko:K05816,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00198,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.3	-	-	ABC_tran,TOBE_2
TLS3_k127_7558722_0	1242864.D187_001102	9.756e-210	664.0	COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,42ZYH@68525|delta/epsilon subdivisions,2WVEZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Alpha-amylase domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,CBM_20,DUF3459
TLS3_k127_7558722_3	404589.Anae109_2423	1.809e-119	398.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,42N4Y@68525|delta/epsilon subdivisions,2WKGT@28221|Deltaproteobacteria,2YXYB@29|Myxococcales	28221|Deltaproteobacteria	S	DinB superfamily	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_31
TLS3_k127_7593546_3	404589.Anae109_2389	1.088e-17	98.0	COG1877@1|root,COG1877@2|Bacteria,1Q1R2@1224|Proteobacteria,42U7I@68525|delta/epsilon subdivisions,2WQZE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
TLS3_k127_7593546_0	404589.Anae109_2390	1.799e-314	979.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,42NBU@68525|delta/epsilon subdivisions,2WJX9@28221|Deltaproteobacteria,2YU3V@29|Myxococcales	28221|Deltaproteobacteria	G	glycosyl transferase family	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
TLS3_k127_7593546_4	1242864.D187_002591	3.302e-06	57.0	COG3012@1|root,COG3012@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
TLS3_k127_7593546_1	404589.Anae109_0581	1.037e-59	218.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_35,CBM_6,CHRD,Calx-beta,DUF4347,DUF4397,He_PIG
TLS3_k127_7600443_4	404589.Anae109_1114	4.653e-13	76.0	COG3330@1|root,COG3330@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4912)	-	-	-	ko:K09942	-	-	-	-	ko00000	-	-	-	DUF4912,Rho_N
TLS3_k127_7600443_1	404589.Anae109_1112	6.438e-134	443.0	COG4775@1|root,COG4775@2|Bacteria,1PBXZ@1224|Proteobacteria,433TZ@68525|delta/epsilon subdivisions,2X3G3@28221|Deltaproteobacteria,2YVY6@29|Myxococcales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
TLS3_k127_7600443_0	290397.Adeh_1071	4.835e-192	626.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2YV0J@29|Myxococcales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
TLS3_k127_7600443_3	404589.Anae109_1109	5.485e-104	360.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,42KZX@68525|delta/epsilon subdivisions,2WM2N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.381	ko:K16066	ko00240,ko00260,ko01100,map00240,map00260,map01100	-	R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000	-	-	-	adh_short
TLS3_k127_7600443_2	404589.Anae109_1105	1.869e-109	371.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2YTZW@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_7634892_0	290397.Adeh_1520	6.793e-134	428.0	COG0539@1|root,COG1185@1|root,COG0539@2|Bacteria,COG1185@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2YU9B@29|Myxococcales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
TLS3_k127_7634892_1	1549858.MC45_17125	2.947e-33	147.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,2TVJ5@28211|Alphaproteobacteria,2K1YB@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
TLS3_k127_7670737_7	522306.CAP2UW1_0287	8.277e-06	56.0	2B4TG@1|root,31XK1@2|Bacteria,1RIY8@1224|Proteobacteria,2VTMB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7670737_3	290397.Adeh_4231	6.858e-86	294.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,42VWF@68525|delta/epsilon subdivisions,2WRX8@28221|Deltaproteobacteria,2YVKZ@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
TLS3_k127_7670737_0	404589.Anae109_4383	3.086e-213	673.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2WJSW@28221|Deltaproteobacteria,2YUEU@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
TLS3_k127_7670737_1	404589.Anae109_4384	1.835e-175	558.0	COG0006@1|root,COG0006@2|Bacteria,1NS4T@1224|Proteobacteria,439D0@68525|delta/epsilon subdivisions,2X4MK@28221|Deltaproteobacteria,2Z068@29|Myxococcales	28221|Deltaproteobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
TLS3_k127_7670737_2	290397.Adeh_4247	1.318e-107	359.0	COG2267@1|root,COG2267@2|Bacteria,1PXRQ@1224|Proteobacteria,434SS@68525|delta/epsilon subdivisions,2X90B@28221|Deltaproteobacteria,2Z19P@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_7670737_4	290397.Adeh_4248	1.234e-61	213.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,2YVH0@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
TLS3_k127_7670737_5	404589.Anae109_4398	1.871e-09	59.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
TLS3_k127_7697614_7	1144275.COCOR_00919	1.541e-20	93.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,4301R@68525|delta/epsilon subdivisions,2WVCA@28221|Deltaproteobacteria,2YYZK@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_7697614_5	215803.DB30_5766	4.846e-29	127.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YY7A@29|Myxococcales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_7697614_0	404589.Anae109_2748	0.0	1673.0	COG0493@1|root,COG0543@1|root,COG1633@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,COG1633@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	nfnA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
TLS3_k127_7697614_4	404589.Anae109_2932	1.262e-48	195.0	COG1942@1|root,COG1942@2|Bacteria,1PYHJ@1224|Proteobacteria,4318D@68525|delta/epsilon subdivisions,2WWZY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	4-Oxalocrotonate Tautomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7697614_3	1144275.COCOR_07709	3.038e-58	216.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,42PVD@68525|delta/epsilon subdivisions,2WN8S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS3_k127_7697614_1	404589.Anae109_3496	1.512e-183	604.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
TLS3_k127_7697614_2	518766.Rmar_1596	2.931e-90	312.0	COG0010@1|root,COG0010@2|Bacteria,4NEFA@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the arginase family	hutG	-	3.5.3.7,3.5.3.8	ko:K01479,ko:K12255	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045	R01990,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS3_k127_7697614_6	518766.Rmar_1595	1.523e-23	103.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes	976|Bacteroidetes	Q	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_7750732_2	404589.Anae109_3196	1.197e-176	556.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2YTX6@29|Myxococcales	28221|Deltaproteobacteria	E	Cys Met metabolism	-	-	2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
TLS3_k127_7750732_0	290397.Adeh_1870	3.221e-242	765.0	COG1196@1|root,COG1196@2|Bacteria,1R3XQ@1224|Proteobacteria,42YF5@68525|delta/epsilon subdivisions,2WUDV@28221|Deltaproteobacteria,2YUE5@29|Myxococcales	28221|Deltaproteobacteria	D	HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid
TLS3_k127_7750732_4	290397.Adeh_1868	1.247e-27	114.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
TLS3_k127_7750732_1	290397.Adeh_1867	2.552e-201	635.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42Z0A@68525|delta/epsilon subdivisions,2WUAC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_7750732_3	404589.Anae109_1973	8.824e-67	252.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2WR3G@28221|Deltaproteobacteria,2YXS5@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_7768658_0	404589.Anae109_0540	0.0	1142.0	COG0784@1|root,COG0840@1|root,COG1511@1|root,COG2770@1|root,COG5002@1|root,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BZ2@68525|delta/epsilon subdivisions,2X79T@28221|Deltaproteobacteria,2YU1H@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
TLS3_k127_7768658_3	1487953.JMKF01000005_gene617	2.402e-92	324.0	COG1352@1|root,COG1352@2|Bacteria,1G1E5@1117|Cyanobacteria,1H94K@1150|Oscillatoriales	1117|Cyanobacteria	NT	PFAM CheR methyltransferase, SAM binding domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
TLS3_k127_7768658_7	1121920.AUAU01000014_gene2811	1.106e-33	144.0	2E3B5@1|root,32YAP@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
TLS3_k127_7768658_1	404589.Anae109_1262	4.654e-109	358.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,42M21@68525|delta/epsilon subdivisions,2WK4G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
TLS3_k127_7768658_2	686340.Metal_2792	2.424e-99	333.0	COG1366@1|root,COG1366@2|Bacteria,1MVPW@1224|Proteobacteria,1RV30@1236|Gammaproteobacteria,1XGQE@135618|Methylococcales	135618|Methylococcales	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
TLS3_k127_7768658_6	667632.KB890164_gene2211	1.51e-40	156.0	COG1366@1|root,COG1366@2|Bacteria,1RJM8@1224|Proteobacteria,2VT28@28216|Betaproteobacteria,1K7XA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	rsbS	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	STAS
TLS3_k127_7768658_4	667632.KB890164_gene2210	2.022e-49	179.0	COG2172@1|root,COG2172@2|Bacteria,1MZIF@1224|Proteobacteria,2VSW8@28216|Betaproteobacteria,1K88Q@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
TLS3_k127_7768658_5	667632.KB890164_gene2209	1.83e-46	178.0	COG2208@1|root,COG2208@2|Bacteria,1N9UZ@1224|Proteobacteria	1224|Proteobacteria	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K05518	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
TLS3_k127_7775928_2	290397.Adeh_1652	4.522e-46	171.0	COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,42NWS@68525|delta/epsilon subdivisions,2X60R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
TLS3_k127_7775928_1	290397.Adeh_1650	2.44e-106	356.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2WNDB@28221|Deltaproteobacteria,2YVFW@29|Myxococcales	28221|Deltaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
TLS3_k127_7775928_0	404589.Anae109_2160	6.764e-151	483.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,42NBN@68525|delta/epsilon subdivisions,2WK8A@28221|Deltaproteobacteria,2YU28@29|Myxococcales	28221|Deltaproteobacteria	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
TLS3_k127_7775928_3	756883.Halar_2774	5.759e-08	63.0	COG1266@1|root,arCOG02766@2157|Archaea	2157|Archaea	S	metal-dependent membrane protease	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
TLS3_k127_7775928_4	246197.MXAN_5097	9.651e-07	52.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,42NR8@68525|delta/epsilon subdivisions,2WM9T@28221|Deltaproteobacteria,2Z05D@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_7807181_9	404589.Anae109_3219	1.903e-98	347.0	COG0673@1|root,COG0673@2|Bacteria,1NKUI@1224|Proteobacteria,43A3J@68525|delta/epsilon subdivisions,2WTZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_7807181_6	483219.LILAB_00545	1.122e-125	427.0	COG1063@1|root,COG1063@2|Bacteria,1MUK8@1224|Proteobacteria,42W1B@68525|delta/epsilon subdivisions,2WREN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_7807181_4	404589.Anae109_3217	9.513e-154	496.0	COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,42NV5@68525|delta/epsilon subdivisions,2WM5C@28221|Deltaproteobacteria,2YYZF@29|Myxococcales	28221|Deltaproteobacteria	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
TLS3_k127_7807181_3	404589.Anae109_3216	6.559e-171	544.0	COG0451@1|root,COG0451@2|Bacteria,1MVI8@1224|Proteobacteria,42R49@68525|delta/epsilon subdivisions,2WNEZ@28221|Deltaproteobacteria,2YU32@29|Myxococcales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
TLS3_k127_7807181_1	404589.Anae109_3215	3.524e-179	566.0	COG4641@1|root,COG4641@2|Bacteria,1MXSZ@1224|Proteobacteria,42Z32@68525|delta/epsilon subdivisions,2WTPV@28221|Deltaproteobacteria,2YZI3@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
TLS3_k127_7807181_2	404589.Anae109_3214	9.384e-175	556.0	COG4641@1|root,COG4641@2|Bacteria,1R4AN@1224|Proteobacteria,42PZP@68525|delta/epsilon subdivisions,2WJGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DUF based on E. rectale Gene description (DUF3880)	-	-	-	ko:K06320	-	-	-	-	ko00000	-	-	-	DUF3880,Glyco_trans_1_2
TLS3_k127_7807181_0	1242864.D187_001978	3.042e-206	650.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TLS3_k127_7807181_7	404589.Anae109_3212	5.591e-121	392.0	COG1209@1|root,COG1209@2|Bacteria,1PKBK@1224|Proteobacteria,42YC4@68525|delta/epsilon subdivisions,2WU52@28221|Deltaproteobacteria,2YYIB@29|Myxococcales	28221|Deltaproteobacteria	M	PFAM Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
TLS3_k127_7807181_5	404589.Anae109_3211	5.274e-150	484.0	COG4641@1|root,COG4641@2|Bacteria,1MUW9@1224|Proteobacteria,42Z5Z@68525|delta/epsilon subdivisions,2WU07@28221|Deltaproteobacteria,2YXPW@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
TLS3_k127_7807181_10	404589.Anae109_1903	1.319e-83	288.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,42QW6@68525|delta/epsilon subdivisions,2X6EN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	-	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
TLS3_k127_7807181_8	404589.Anae109_1904	1.44e-114	374.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,42QV7@68525|delta/epsilon subdivisions,2WMPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
TLS3_k127_7807181_11	404589.Anae109_1906	1.846e-57	206.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,2YURG@29|Myxococcales	28221|Deltaproteobacteria	L	A G-specific	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
TLS3_k127_7811051_2	864051.BurJ1DRAFT_4865	3.411e-117	392.0	COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,2VVJQ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TLS3_k127_7811051_3	196162.Noca_1660	1.056e-22	111.0	COG0664@1|root,COG0664@2|Bacteria,2IINQ@201174|Actinobacteria	201174|Actinobacteria	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K21564	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TLS3_k127_7811051_1	448385.sce6347	6.145e-134	446.0	COG0668@1|root,COG0668@2|Bacteria,1MW7V@1224|Proteobacteria,42R90@68525|delta/epsilon subdivisions,2WMUJ@28221|Deltaproteobacteria,2YWD8@29|Myxococcales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	mscS-2	-	-	-	-	-	-	-	-	-	-	-	MS_channel
TLS3_k127_7811051_0	398767.Glov_2549	9.41e-152	485.0	COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,43BKE@68525|delta/epsilon subdivisions,2X6YE@28221|Deltaproteobacteria,43UBK@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
TLS3_k127_7815215_3	105559.Nwat_1349	7.341e-145	466.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1X04R@135613|Chromatiales	135613|Chromatiales	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K15408	ko00190,map00190	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX1
TLS3_k127_7815215_11	105559.Nwat_1350	1.752e-34	149.0	2E5ZP@1|root,330P3@2|Bacteria,1MZC5@1224|Proteobacteria,1SQH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7815215_8	243090.RB4410	2.832e-67	241.0	COG3336@1|root,COG3336@2|Bacteria,2J2XG@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	ko:K02351	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
TLS3_k127_7815215_4	1333856.L686_11865	5.634e-115	392.0	COG2010@1|root,COG2863@1|root,COG2010@2|Bacteria,COG2863@2|Bacteria,1MW1W@1224|Proteobacteria,1SYTA@1236|Gammaproteobacteria,1Z3W0@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
TLS3_k127_7815215_10	595460.RRSWK_05955	1.334e-59	233.0	COG0530@1|root,COG0530@2|Bacteria,2J283@203682|Planctomycetes	203682|Planctomycetes	P	COG0530 Ca2 Na antiporter	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
TLS3_k127_7815215_12	1077972.ARGLB_113_00250	4.89e-09	63.0	2AZF8@1|root,31RP4@2|Bacteria,2IH9G@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7815215_5	290397.Adeh_2660	2.047e-106	355.0	COG4221@1|root,COG4221@2|Bacteria,1MUU6@1224|Proteobacteria,42YQ8@68525|delta/epsilon subdivisions,2WU8K@28221|Deltaproteobacteria,2YZNE@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_7815215_1	1144275.COCOR_05821	1.502e-228	726.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,42P6Z@68525|delta/epsilon subdivisions,2WK5W@28221|Deltaproteobacteria,2YUMK@29|Myxococcales	28221|Deltaproteobacteria	G	Maltogenic Amylase, C-terminal domain	-	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
TLS3_k127_7815215_9	290397.Adeh_4132	8.539e-67	244.0	COG4580@1|root,COG4580@2|Bacteria,1MX77@1224|Proteobacteria,42W2G@68525|delta/epsilon subdivisions,2WSCH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	LamB porin	-	-	-	ko:K02024	-	-	-	-	ko00000,ko02000	1.B.3.1.1	-	-	LamB
TLS3_k127_7815215_0	1279038.KB907341_gene1987	3.239e-274	871.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2TR28@28211|Alphaproteobacteria,2JPGP@204441|Rhodospirillales	204441|Rhodospirillales	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183,ko:K11189	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr,PTS_EIIA_2
TLS3_k127_7815215_6	640510.BC1001_4250	6.81e-81	296.0	COG1105@1|root,COG1105@2|Bacteria,1MVNW@1224|Proteobacteria,2VPIP@28216|Betaproteobacteria,1KFS2@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Belongs to the carbohydrate kinase PfkB family	fruK	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
TLS3_k127_7815215_2	925775.XVE_2746	5.845e-198	632.0	COG1299@1|root,COG1445@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,1MXFN@1224|Proteobacteria,1RMZC@1236|Gammaproteobacteria,1X40T@135614|Xanthomonadales	135614|Xanthomonadales	G	PTS system, fructose-specific	fruA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090582	2.7.1.202	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIC,PTS_IIB
TLS3_k127_7815215_7	1396141.BATP01000039_gene1352	1.933e-80	273.0	COG0406@1|root,COG0406@2|Bacteria,46T4J@74201|Verrucomicrobia,2IV5M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
TLS3_k127_7836723_7	404589.Anae109_0631	2.677e-30	139.0	COG1438@1|root,COG1438@2|Bacteria,1N2AF@1224|Proteobacteria,435GT@68525|delta/epsilon subdivisions,2WZUC@28221|Deltaproteobacteria,2Z2RY@29|Myxococcales	28221|Deltaproteobacteria	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
TLS3_k127_7836723_0	404589.Anae109_0632	0.0	1112.0	COG0548@1|root,COG1364@1|root,COG0548@2|Bacteria,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2WJU8@28221|Deltaproteobacteria,2YV2H@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	-	-	2.3.1.1,2.3.1.35,2.7.2.8	ko:K00620,ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282,R02649	RC00002,RC00004,RC00043,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ArgJ
TLS3_k127_7836723_3	404589.Anae109_0633	2.083e-144	466.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,2YTTI@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145,ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00028,M00031,M00763,M00845	R03443,R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
TLS3_k127_7836723_4	290397.Adeh_2040	2.163e-105	357.0	COG1639@1|root,COG1639@2|Bacteria,1QIEZ@1224|Proteobacteria,42PKV@68525|delta/epsilon subdivisions,2WKGI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
TLS3_k127_7836723_1	290397.Adeh_0591	8.325e-179	570.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WMS6@28221|Deltaproteobacteria,2Z30T@29|Myxococcales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
TLS3_k127_7836723_2	404589.Anae109_0637	2.824e-162	522.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2YUII@29|Myxococcales	28221|Deltaproteobacteria	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
TLS3_k127_784364_2	1242864.D187_000820	4.726e-37	156.0	2EWVG@1|root,33Q6Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_784364_4	404380.Gbem_1080	8.739e-23	112.0	COG3979@1|root,COG4447@1|root,COG3979@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	chiA	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.2.1.132,3.2.1.14,3.2.1.17	ko:K01183,ko:K01233,ko:K13381	ko00520,ko01100,map00520,map01100	-	R01206,R02334,R02833	RC00467	ko00000,ko00001,ko01000	-	CBM15,GH18	-	CBM_5_12,Glyco_hydro_18,LPMO_10,fn3
TLS3_k127_784364_1	404589.Anae109_2633	5.884e-193	615.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MJD@68525|delta/epsilon subdivisions,2WJC4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	epsN	-	-	ko:K19430	-	-	-	-	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_784364_3	1123023.JIAI01000007_gene1679	1.072e-35	148.0	COG2263@1|root,COG2263@2|Bacteria	2|Bacteria	J	DNA repair	-	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0036260,GO:0036261,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071164,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
TLS3_k127_784364_0	404589.Anae109_3731	0.0	1102.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA
TLS3_k127_784364_5	247634.GPB2148_1892	6.243e-11	75.0	COG3202@1|root,COG3202@2|Bacteria,1QXXQ@1224|Proteobacteria,1S2KU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	TLC ATP/ADP transporter	-	-	-	-	-	-	-	-	-	-	-	-	TLC
TLS3_k127_7872936_5	871963.Desdi_1785	4.458e-16	84.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,24P0N@186801|Clostridia,2670K@186807|Peptococcaceae	186801|Clostridia	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
TLS3_k127_7872936_3	448385.sce3271	3.055e-55	203.0	COG0406@1|root,COG0406@2|Bacteria,1QNKS@1224|Proteobacteria,434AH@68525|delta/epsilon subdivisions,2WYK2@28221|Deltaproteobacteria,2Z1NH@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
TLS3_k127_7872936_2	1254432.SCE1572_19995	9.09e-65	241.0	COG0510@1|root,COG0510@2|Bacteria,1NUEU@1224|Proteobacteria	1224|Proteobacteria	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
TLS3_k127_7872936_0	404589.Anae109_1439	0.0	1318.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,1MU6Y@1224|Proteobacteria,42M5I@68525|delta/epsilon subdivisions,2WK8Y@28221|Deltaproteobacteria,2YUG8@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8
TLS3_k127_7872936_6	1125718.HMPREF1318_2823	4.287e-06	61.0	COG0745@1|root,COG0745@2|Bacteria,2IGM3@201174|Actinobacteria,4D5KA@85005|Actinomycetales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_7872936_7	448385.sce8791	6.179e-05	51.0	2AGZU@1|root,3178K@2|Bacteria,1PYIG@1224|Proteobacteria,43E50@68525|delta/epsilon subdivisions,2WZR6@28221|Deltaproteobacteria,2Z2JU@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7872936_4	1307436.PBF_19024	1.316e-22	104.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,1ZCZ4@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_7872936_1	1192034.CAP_4198	4.217e-138	449.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2YWC8@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_7873027_10	290397.Adeh_1662	1.218e-59	214.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,42VYV@68525|delta/epsilon subdivisions,2WRGQ@28221|Deltaproteobacteria,2Z0X7@29|Myxococcales	28221|Deltaproteobacteria	K	MerR, DNA binding	-	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
TLS3_k127_7873027_2	290397.Adeh_1664	4.295e-150	512.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2YU5D@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_7873027_0	404589.Anae109_2136	1.591e-207	649.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2YXAE@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_7873027_9	404589.Anae109_2135	1.854e-112	368.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria,2YWMX@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1716	ECH_1
TLS3_k127_7873027_4	290397.Adeh_1667	2.572e-126	433.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42M6J@68525|delta/epsilon subdivisions,2WJZQ@28221|Deltaproteobacteria,2YWS8@29|Myxococcales	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
TLS3_k127_7873027_5	290397.Adeh_1668	3.111e-125	417.0	COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CC6@68525|delta/epsilon subdivisions,2X7N2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
TLS3_k127_7873027_7	543728.Vapar_2570	6.289e-117	392.0	COG1028@1|root,COG1028@2|Bacteria,1MVKN@1224|Proteobacteria,2VJCW@28216|Betaproteobacteria,4AEES@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
TLS3_k127_7873027_12	290397.Adeh_1673	1.638e-27	127.0	2CIY5@1|root,2ZET1@2|Bacteria,1P8MM@1224|Proteobacteria,4330I@68525|delta/epsilon subdivisions,2WXKY@28221|Deltaproteobacteria,2YW19@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7873027_6	290397.Adeh_1674	2.005e-122	397.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2WIPG@28221|Deltaproteobacteria,2YU3H@29|Myxococcales	28221|Deltaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
TLS3_k127_7873027_8	404589.Anae109_2129	7.48e-114	376.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,2YV6M@29|Myxococcales	28221|Deltaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284,ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3,1.A.35.4	-	-	CorA
TLS3_k127_7873027_1	404589.Anae109_2128	1.749e-162	518.0	COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,42ZNT@68525|delta/epsilon subdivisions,2WUVT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
TLS3_k127_7873027_3	290397.Adeh_1677	3.963e-145	470.0	COG1055@1|root,COG1055@2|Bacteria,1NEVR@1224|Proteobacteria,42NU5@68525|delta/epsilon subdivisions,2WJV4@28221|Deltaproteobacteria,2YX9Q@29|Myxococcales	28221|Deltaproteobacteria	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
TLS3_k127_7873027_11	404589.Anae109_2126	3.371e-39	152.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42V72@68525|delta/epsilon subdivisions,2WRHE@28221|Deltaproteobacteria,2Z1JS@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_7882970_8	378806.STAUR_3434	5.262e-43	171.0	COG5592@1|root,COG5592@2|Bacteria,1RI8J@1224|Proteobacteria,42XM7@68525|delta/epsilon subdivisions,2WSTY@28221|Deltaproteobacteria,2YWYZ@29|Myxococcales	28221|Deltaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
TLS3_k127_7882970_9	290397.Adeh_2217	3.992e-41	162.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,2YVH0@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
TLS3_k127_7882970_2	404589.Anae109_3636	1.936e-236	766.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42M8M@68525|delta/epsilon subdivisions,2WJE2@28221|Deltaproteobacteria,2YXXW@29|Myxococcales	28221|Deltaproteobacteria	P	ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
TLS3_k127_7882970_5	1254432.SCE1572_46490	2.686e-122	404.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PZJ@68525|delta/epsilon subdivisions,2WMGB@28221|Deltaproteobacteria,2YVBK@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
TLS3_k127_7882970_1	290397.Adeh_1766	7.751e-250	792.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2WIWB@28221|Deltaproteobacteria,2YX7D@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA1	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
TLS3_k127_7882970_4	404589.Anae109_2050	8.814e-131	448.0	2EM41@1|root,33ETI@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
TLS3_k127_7882970_6	290397.Adeh_1768	7.701e-117	382.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42QN5@68525|delta/epsilon subdivisions,2WMD7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_7882970_3	290397.Adeh_1771	2.303e-161	526.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
TLS3_k127_7882970_0	404589.Anae109_2043	0.0	1069.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJZ3@28221|Deltaproteobacteria,2YXF9@29|Myxococcales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
TLS3_k127_7882970_7	404589.Anae109_2042	2.477e-63	219.0	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,42T10@68525|delta/epsilon subdivisions,2WPNN@28221|Deltaproteobacteria,2YVNK@29|Myxococcales	28221|Deltaproteobacteria	L	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,NUDIX_4
TLS3_k127_7882970_10	404589.Anae109_2040	4.11e-22	99.0	COG0646@1|root,COG0646@2|Bacteria,1NPFY@1224|Proteobacteria,43BU7@68525|delta/epsilon subdivisions,2X757@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10,2.1.1.13	ko:K00297,ko:K00547,ko:K00548	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,ko01523,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230,map01523	M00017,M00377	R00650,R00946,R01224,R07168,R09365	RC00003,RC00035,RC00081,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
TLS3_k127_7889851_12	1163617.SCD_n02012	6.999e-15	78.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_7889851_8	290397.Adeh_0655	1.93e-96	325.0	COG4359@1|root,COG4359@2|Bacteria,1NMH7@1224|Proteobacteria,42UTM@68525|delta/epsilon subdivisions,2WQSI@28221|Deltaproteobacteria,2Z27X@29|Myxococcales	28221|Deltaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.87	ko:K08966	ko00270,ko01100,map00270,map01100	M00034	R07394	RC02074	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD
TLS3_k127_7889851_4	870187.Thini_1137	1.777e-135	458.0	COG0784@1|root,COG5000@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
TLS3_k127_7889851_0	1384054.N790_13150	1.785e-257	802.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,1RM8P@1236|Gammaproteobacteria,1X52H@135614|Xanthomonadales	135614|Xanthomonadales	E	Transporter	ygdR	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
TLS3_k127_7889851_10	314265.R2601_10859	2.818e-45	185.0	COG3485@1|root,COG3485@2|Bacteria,1MV6K@1224|Proteobacteria,2TUS4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	intradiol ring-cleavage dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
TLS3_k127_7889851_5	290397.Adeh_0221	7.778e-129	419.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2WJMZ@28221|Deltaproteobacteria,2Z0DM@29|Myxococcales	28221|Deltaproteobacteria	M	RmlD substrate binding domain	uge	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
TLS3_k127_7889851_1	404589.Anae109_4199	6.203e-186	601.0	COG1807@1|root,COG1807@2|Bacteria,1RJ9T@1224|Proteobacteria	1224|Proteobacteria	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
TLS3_k127_7889851_7	404589.Anae109_4197	6.473e-103	360.0	COG0392@1|root,COG0392@2|Bacteria,1R5YC@1224|Proteobacteria	1224|Proteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
TLS3_k127_7889851_3	404589.Anae109_4198	6.346e-154	505.0	COG1215@1|root,COG1215@2|Bacteria,1QTWU@1224|Proteobacteria,43CQN@68525|delta/epsilon subdivisions,2X7Y4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_7889851_6	404589.Anae109_2934	5.385e-106	359.0	COG0642@1|root,COG2205@2|Bacteria,1R7QH@1224|Proteobacteria,42PSC@68525|delta/epsilon subdivisions,2WKFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
TLS3_k127_7889851_9	290397.Adeh_0968	1.266e-67	244.0	28JRZ@1|root,2Z9HI@2|Bacteria,1R52Z@1224|Proteobacteria,42R46@68525|delta/epsilon subdivisions,2WMF2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
TLS3_k127_7889851_2	404589.Anae109_4301	8.213e-168	539.0	COG1793@1|root,COG1793@2|Bacteria,1MV3S@1224|Proteobacteria,430DD@68525|delta/epsilon subdivisions,2WVKB@28221|Deltaproteobacteria,2YUBR@29|Myxococcales	28221|Deltaproteobacteria	F	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	ligB	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
TLS3_k127_7895515_10	598659.NAMH_1184	1.644e-12	73.0	2AY0S@1|root,31Q2B@2|Bacteria,1QMQY@1224|Proteobacteria,42SY0@68525|delta/epsilon subdivisions,2YPGA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacteriophage replication gene A protein (GPA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPA
TLS3_k127_7895515_5	404589.Anae109_1537	5.981e-84	297.0	COG1108@1|root,COG1108@2|Bacteria,1Q1G9@1224|Proteobacteria,4378R@68525|delta/epsilon subdivisions,2X2BN@28221|Deltaproteobacteria,2YX1Q@29|Myxococcales	28221|Deltaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
TLS3_k127_7895515_4	404589.Anae109_1536	1.551e-84	296.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2WKMZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
TLS3_k127_7895515_3	404589.Anae109_1535	8.743e-97	332.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2WQ7S@28221|Deltaproteobacteria,2YTZ9@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
TLS3_k127_7895515_2	404589.Anae109_1534	9.854e-104	348.0	COG3170@1|root,COG3170@2|Bacteria,1QX7F@1224|Proteobacteria,42NQR@68525|delta/epsilon subdivisions,2WRZ7@28221|Deltaproteobacteria,2YYH9@29|Myxococcales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7895515_1	290397.Adeh_2342	7.204e-175	556.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,42PNZ@68525|delta/epsilon subdivisions,2WM13@28221|Deltaproteobacteria,2YUDU@29|Myxococcales	28221|Deltaproteobacteria	C	CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
TLS3_k127_7895515_8	290397.Adeh_2343	1.52e-44	164.0	COG3255@1|root,COG3255@2|Bacteria,1PWYZ@1224|Proteobacteria,432A7@68525|delta/epsilon subdivisions,2WXR1@28221|Deltaproteobacteria,2YW4M@29|Myxococcales	28221|Deltaproteobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
TLS3_k127_7895515_7	404589.Anae109_1530	2.201e-56	198.0	COG3437@1|root,COG3437@2|Bacteria,1QYG6@1224|Proteobacteria,43CCB@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_7895515_0	215803.DB30_4963	9.216e-190	615.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2YWT8@29|Myxococcales	28221|Deltaproteobacteria	I	Amp-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
TLS3_k127_7895515_6	290397.Adeh_2346	8.166e-74	257.0	COG3071@1|root,COG3071@2|Bacteria,1NNBM@1224|Proteobacteria,42XVS@68525|delta/epsilon subdivisions,2WT7H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	HemY protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_17,TPR_19
TLS3_k127_7918944_4	290397.Adeh_1450	1.074e-20	91.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_7918944_6	1123511.KB905854_gene3608	1.456e-13	75.0	2DTV6@1|root,32UW0@2|Bacteria,1VEAB@1239|Firmicutes,4H5G3@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7918944_2	290397.Adeh_2494	2.422e-54	203.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,2Z3NJ@29|Myxococcales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
TLS3_k127_7918944_1	404589.Anae109_4330	1.461e-109	366.0	COG0491@1|root,COG0491@2|Bacteria,1PJNG@1224|Proteobacteria,437NT@68525|delta/epsilon subdivisions,2X2X1@28221|Deltaproteobacteria,2YZNC@29|Myxococcales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
TLS3_k127_7918944_7	404589.Anae109_3207	2.3e-12	74.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,42MY6@68525|delta/epsilon subdivisions,2WME2@28221|Deltaproteobacteria,2YWHE@29|Myxococcales	28221|Deltaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_7918944_3	153948.NAL212_2398	1.102e-25	124.0	COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,372V5@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	EAL,GGDEF,HAMP,LapD_MoxY_N,PAS,PAS_3,PAS_4,PAS_9
TLS3_k127_7918944_0	404589.Anae109_2356	6.034e-114	394.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2X7XX@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
TLS3_k127_7918944_5	1500301.JQMF01000005_gene3765	1.047e-19	93.0	COG4274@1|root,COG4274@2|Bacteria,1RKGA@1224|Proteobacteria,2UAJZ@28211|Alphaproteobacteria,4BERT@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
TLS3_k127_7930007_5	404589.Anae109_1754	2.365e-34	136.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YUGJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
TLS3_k127_7930007_0	404589.Anae109_1753	2.933e-286	889.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MAV@68525|delta/epsilon subdivisions,2WJC9@28221|Deltaproteobacteria,2YW7U@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
TLS3_k127_7930007_2	926569.ANT_03320	1.645e-74	272.0	COG0066@1|root,COG0066@2|Bacteria,2G6JE@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
TLS3_k127_7930007_1	926569.ANT_03310	3.815e-218	700.0	COG0065@1|root,COG0065@2|Bacteria,2G68G@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
TLS3_k127_7930007_3	296591.Bpro_0708	3.053e-42	164.0	COG3447@1|root,COG4585@1|root,COG3447@2|Bacteria,COG4585@2|Bacteria,1PF0H@1224|Proteobacteria,2W8ZC@28216|Betaproteobacteria,4AI7H@80864|Comamonadaceae	28216|Betaproteobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,MASE1
TLS3_k127_7936295_8	290397.Adeh_0709	7.141e-20	89.0	COG3930@1|root,COG3930@2|Bacteria,1PYFH@1224|Proteobacteria,42ZAK@68525|delta/epsilon subdivisions,2WUH8@28221|Deltaproteobacteria,2YUXI@29|Myxococcales	28221|Deltaproteobacteria	S	DUF1704	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704,FGase
TLS3_k127_7936295_0	290397.Adeh_0710	7.2e-135	445.0	COG1633@1|root,COG1814@1|root,COG1633@2|Bacteria,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,42UMC@68525|delta/epsilon subdivisions,2WQJQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
TLS3_k127_7936295_2	110662.Syncc9605_2070	2.359e-112	386.0	COG0141@1|root,COG0141@2|Bacteria,1G1I2@1117|Cyanobacteria,1GYAR@1129|Synechococcus	1117|Cyanobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
TLS3_k127_7936295_6	671143.DAMO_2244	7.248e-69	259.0	COG0079@1|root,COG0079@2|Bacteria,2NPHF@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_7936295_3	290397.Adeh_0713	2.542e-100	332.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,42NIV@68525|delta/epsilon subdivisions,2WNA4@28221|Deltaproteobacteria,2YV6W@29|Myxococcales	28221|Deltaproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
TLS3_k127_7936295_5	290397.Adeh_0714	2.824e-86	302.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,42QX8@68525|delta/epsilon subdivisions,2WMNR@28221|Deltaproteobacteria,2YV5Y@29|Myxococcales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
TLS3_k127_7936295_4	404589.Anae109_0756	2.906e-89	311.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,42NRX@68525|delta/epsilon subdivisions,2WK1K@28221|Deltaproteobacteria,2YVBU@29|Myxococcales	28221|Deltaproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0388	His_biosynth
TLS3_k127_7936295_1	404589.Anae109_0757	2.201e-134	433.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2WJFW@28221|Deltaproteobacteria,2YUN8@29|Myxococcales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
TLS3_k127_7936295_9	1353537.TP2_08625	6.271e-10	65.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2UBU3@28211|Alphaproteobacteria,2XNIH@285107|Thioclava	28211|Alphaproteobacteria	E	Phosphoribosyl-ATP pyrophosphatase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
TLS3_k127_7936295_7	290397.Adeh_0718	3.961e-24	103.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,42V6T@68525|delta/epsilon subdivisions,2WRAX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
TLS3_k127_7957157_2	1244869.H261_12481	2.943e-194	611.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2TSHT@28211|Alphaproteobacteria,2JPS4@204441|Rhodospirillales	204441|Rhodospirillales	EH	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
TLS3_k127_7957157_1	290397.Adeh_1265	6.996e-220	689.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2WJ3F@28221|Deltaproteobacteria,2YUGA@29|Myxococcales	28221|Deltaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
TLS3_k127_7957157_3	404589.Anae109_2505	2.53e-147	473.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,42MK1@68525|delta/epsilon subdivisions,2WK5D@28221|Deltaproteobacteria,2Z2YR@29|Myxococcales	28221|Deltaproteobacteria	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
TLS3_k127_7957157_0	290397.Adeh_1262	5.42e-237	743.0	COG1052@1|root,COG1052@2|Bacteria,1REXX@1224|Proteobacteria,42R07@68525|delta/epsilon subdivisions,2X7JR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.310,1.1.1.399,1.1.1.95	ko:K00058,ko:K16843	ko00260,ko00270,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513,R05693	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
TLS3_k127_7957157_4	404589.Anae109_2507	1.613e-75	267.0	COG1309@1|root,COG1309@2|Bacteria,1RCDH@1224|Proteobacteria,42VJ5@68525|delta/epsilon subdivisions,2WXCH@28221|Deltaproteobacteria,2Z381@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
TLS3_k127_7957157_6	290397.Adeh_1260	5.55e-25	109.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA_C
TLS3_k127_7989579_3	1242864.D187_008374	1.068e-54	192.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2WJW9@28221|Deltaproteobacteria,2YTWD@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0899	F420_oxidored,P5CR_dimer
TLS3_k127_7989579_0	290397.Adeh_2484	1.037e-281	875.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
TLS3_k127_7989579_5	290397.Adeh_2485	2.356e-17	83.0	COG3729@1|root,COG3729@2|Bacteria,1P5W4@1224|Proteobacteria	1224|Proteobacteria	S	Small hydrophilic plant seed protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_5
TLS3_k127_7989579_1	404589.Anae109_1381	1.829e-98	327.0	COG0613@1|root,COG0613@2|Bacteria,1RF04@1224|Proteobacteria,42RR4@68525|delta/epsilon subdivisions,2WNC8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM PHP domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP,PHP_C
TLS3_k127_8025103_1	861299.J421_1931	3.148e-198	632.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K22348	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
TLS3_k127_8025103_3	1192034.CAP_7724	1.447e-154	493.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42Z4J@68525|delta/epsilon subdivisions,2WUHY@28221|Deltaproteobacteria,2YWQR@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_8025103_2	404589.Anae109_0564	9.632e-169	547.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria	1224|Proteobacteria	H	Methyl-transferase	egtB	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
TLS3_k127_8025103_0	378806.STAUR_5205	1.521e-281	876.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,42NY8@68525|delta/epsilon subdivisions,2WJNT@28221|Deltaproteobacteria,2YXXC@29|Myxococcales	28221|Deltaproteobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
TLS3_k127_8045431_2	290397.Adeh_4094	2.857e-68	235.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42TKK@68525|delta/epsilon subdivisions,2X5NX@28221|Deltaproteobacteria,2Z0PZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
TLS3_k127_8045431_0	404589.Anae109_0332	2.868e-200	656.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria	1224|Proteobacteria	S	oligopeptide transporter	-	-	-	-	-	-	-	-	-	-	-	-	OPT
TLS3_k127_8045431_1	290397.Adeh_4090	1.922e-79	278.0	COG2244@1|root,COG2244@2|Bacteria,1Q5M0@1224|Proteobacteria,431FY@68525|delta/epsilon subdivisions,2WWCX@28221|Deltaproteobacteria,2Z34S@29|Myxococcales	28221|Deltaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
TLS3_k127_8076486_14	290397.Adeh_3975	1.638e-30	126.0	COG0745@1|root,COG0745@2|Bacteria,1NBDV@1224|Proteobacteria,42UVC@68525|delta/epsilon subdivisions,2WQ45@28221|Deltaproteobacteria,2Z1KX@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_8076486_2	502025.Hoch_0129	2.151e-242	771.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,42NR5@68525|delta/epsilon subdivisions,2WMMK@28221|Deltaproteobacteria,2YU26@29|Myxococcales	28221|Deltaproteobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	pep	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
TLS3_k127_8076486_12	290397.Adeh_3976	8.28e-66	248.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,42VZ2@68525|delta/epsilon subdivisions,2X8TC@28221|Deltaproteobacteria,2YYPQ@29|Myxococcales	28221|Deltaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
TLS3_k127_8076486_5	290397.Adeh_3977	9.34e-154	497.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,42P5V@68525|delta/epsilon subdivisions,2WMWE@28221|Deltaproteobacteria,2YU1I@29|Myxococcales	28221|Deltaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
TLS3_k127_8076486_11	404589.Anae109_0441	1.052e-83	292.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,Abhydrolase_6
TLS3_k127_8076486_6	404589.Anae109_0440	4.2e-140	452.0	COG1638@1|root,COG1638@2|Bacteria,1PJFW@1224|Proteobacteria,42PXK@68525|delta/epsilon subdivisions,2WJFU@28221|Deltaproteobacteria,2Z1WI@29|Myxococcales	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
TLS3_k127_8076486_9	290397.Adeh_3980	1.551e-90	307.0	COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,42Q81@68525|delta/epsilon subdivisions,2WIJ3@28221|Deltaproteobacteria,2Z2J1@29|Myxococcales	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
TLS3_k127_8076486_1	290397.Adeh_3981	2.728e-254	798.0	COG1593@1|root,COG3090@1|root,COG1593@2|Bacteria,COG3090@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2YWE1@29|Myxococcales	28221|Deltaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
TLS3_k127_8076486_3	404589.Anae109_3749	1.555e-224	710.0	28I8B@1|root,2Z8B5@2|Bacteria,1R013@1224|Proteobacteria,42ZRI@68525|delta/epsilon subdivisions,2WUWF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Cytochrome_cB
TLS3_k127_8076486_10	215803.DB30_6950	7.969e-85	299.0	COG1538@1|root,COG1538@2|Bacteria,1PTZ6@1224|Proteobacteria,42RK2@68525|delta/epsilon subdivisions,2X282@28221|Deltaproteobacteria,2YV1K@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_8076486_8	215803.DB30_6949	5.204e-110	387.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42QZT@68525|delta/epsilon subdivisions,2WN4R@28221|Deltaproteobacteria,2YVY4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585,ko:K07799	ko01501,ko01503,ko02020,map01501,map01503,map02020	M00646,M00647,M00648,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS3_k127_8076486_0	246197.MXAN_3903	0.0	1447.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YX7V@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
TLS3_k127_8076486_7	404589.Anae109_0436	4.341e-121	417.0	COG2518@1|root,COG2518@2|Bacteria,1NMMQ@1224|Proteobacteria,42ZGE@68525|delta/epsilon subdivisions,2WUVC@28221|Deltaproteobacteria,2YW9A@29|Myxococcales	28221|Deltaproteobacteria	O	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
TLS3_k127_8076486_4	404589.Anae109_2041	4.764e-193	612.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2YUD9@29|Myxococcales	28221|Deltaproteobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
TLS3_k127_8076486_15	926562.Oweho_3181	2.743e-21	101.0	2DSYW@1|root,33HZI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8076486_13	404589.Anae109_0433	1.568e-38	145.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WJ41@28221|Deltaproteobacteria,2YUJJ@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter, ATP-binding protein	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_8112201_1	404589.Anae109_0946	2.346e-86	292.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,42TVJ@68525|delta/epsilon subdivisions,2WQ0X@28221|Deltaproteobacteria,2Z32X@29|Myxococcales	28221|Deltaproteobacteria	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
TLS3_k127_8112201_2	404589.Anae109_0947	1.693e-68	239.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
TLS3_k127_8112201_3	290397.Adeh_0902	1.846e-19	91.0	28S5K@1|root,2ZEH5@2|Bacteria	2|Bacteria	S	Protein of unknown function (FYDLN_acid)	-	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
TLS3_k127_8112201_0	290397.Adeh_0903	2.982e-140	452.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria,2YTV2@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
TLS3_k127_8112201_4	215803.DB30_0129	3.142e-05	56.0	COG3170@1|root,COG3170@2|Bacteria,1QX3V@1224|Proteobacteria,43BWB@68525|delta/epsilon subdivisions,2X773@28221|Deltaproteobacteria,2YVT2@29|Myxococcales	28221|Deltaproteobacteria	NU	zinc-ribbon domain	agmX	-	-	-	-	-	-	-	-	-	-	-	DUF4339,zinc_ribbon_4
TLS3_k127_8119124_6	404589.Anae109_4154	3.867e-86	291.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria,2YU3N@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TLS3_k127_8119124_4	1278073.MYSTI_01220	6.888e-117	391.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	nla28	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_8119124_5	246197.MXAN_0399	1.12e-108	391.0	COG0642@1|root,COG2205@2|Bacteria,1QX6V@1224|Proteobacteria,43BZK@68525|delta/epsilon subdivisions,2X7AC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4
TLS3_k127_8119124_0	290397.Adeh_0419	2.778e-293	927.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,2YU0Y@29|Myxococcales	28221|Deltaproteobacteria	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
TLS3_k127_8119124_7	404589.Anae109_4149	7.163e-42	163.0	COG2236@1|root,COG2236@2|Bacteria,1NHGS@1224|Proteobacteria	1224|Proteobacteria	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
TLS3_k127_8119124_3	404589.Anae109_4148	2.941e-120	392.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,42Q9R@68525|delta/epsilon subdivisions,2WKU4@28221|Deltaproteobacteria,2Z2YS@29|Myxococcales	28221|Deltaproteobacteria	O	Hsp33 protein	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
TLS3_k127_8119124_1	404589.Anae109_4146	2.244e-151	499.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,42TCH@68525|delta/epsilon subdivisions,2WPEI@28221|Deltaproteobacteria,2YU8R@29|Myxococcales	28221|Deltaproteobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
TLS3_k127_8119124_2	290397.Adeh_0424	7.489e-132	427.0	COG0204@1|root,COG0204@2|Bacteria,1R9IG@1224|Proteobacteria,42T29@68525|delta/epsilon subdivisions,2WPJ8@28221|Deltaproteobacteria,2YUTC@29|Myxococcales	28221|Deltaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TLS3_k127_8119943_2	290397.Adeh_0687	6.883e-110	366.0	COG3031@1|root,COG3031@2|Bacteria,1PUWN@1224|Proteobacteria,42T73@68525|delta/epsilon subdivisions,2WR4E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSC
TLS3_k127_8119943_1	290397.Adeh_0688	3.933e-217	681.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YUJU@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_8119943_3	404589.Anae109_0733	8.667e-36	156.0	COG0254@1|root,COG0254@2|Bacteria,1PT0H@1224|Proteobacteria,42V2Z@68525|delta/epsilon subdivisions,2WRGA@28221|Deltaproteobacteria,2YVT9@29|Myxococcales	28221|Deltaproteobacteria	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
TLS3_k127_8119943_0	404589.Anae109_0734	7.879e-264	815.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria,2YYQJ@29|Myxococcales	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
TLS3_k127_8134845_0	404589.Anae109_2301	1.447e-272	844.0	COG0539@1|root,COG1185@1|root,COG0539@2|Bacteria,COG1185@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2YU9B@29|Myxococcales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
TLS3_k127_8134845_3	404589.Anae109_2302	6.788e-151	481.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,42MJK@68525|delta/epsilon subdivisions,2WJ8V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,UbiA
TLS3_k127_8134845_8	404589.Anae109_2308	4.015e-78	291.0	28H8R@1|root,2Z7KJ@2|Bacteria,1Q390@1224|Proteobacteria,43905@68525|delta/epsilon subdivisions,2X457@28221|Deltaproteobacteria,2YYAC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8134845_7	404589.Anae109_2309	1.264e-96	321.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,42STI@68525|delta/epsilon subdivisions,2WP1K@28221|Deltaproteobacteria,2Z2XF@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
TLS3_k127_8134845_2	404589.Anae109_2311	8.721e-159	505.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2WKA3@28221|Deltaproteobacteria,2YU4X@29|Myxococcales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
TLS3_k127_8134845_6	290397.Adeh_1512	8.422e-106	370.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,2YUX2@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
TLS3_k127_8134845_1	404589.Anae109_2313	1.975e-215	676.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria,2YTVY@29|Myxococcales	28221|Deltaproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
TLS3_k127_8134845_4	290397.Adeh_1509	2.264e-121	412.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,42PAW@68525|delta/epsilon subdivisions,2WJV9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the phosphatidylserine decarboxylase family	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
TLS3_k127_8134845_12	1156919.QWC_25798	0.0004277	49.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1R71B@1224|Proteobacteria,2VI9S@28216|Betaproteobacteria,3T7CZ@506|Alcaligenaceae	28216|Betaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
TLS3_k127_8134845_11	342113.DM82_4166	7.828e-05	46.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,1R6F1@1224|Proteobacteria,2VMW2@28216|Betaproteobacteria,1K3HB@119060|Burkholderiaceae	28216|Betaproteobacteria	P	SMART Rhodanese domain protein	dedA_2	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
TLS3_k127_8134845_9	404589.Anae109_2317	4.543e-43	168.0	COG0622@1|root,COG0622@2|Bacteria,1N8BH@1224|Proteobacteria,43BGF@68525|delta/epsilon subdivisions,2X6UQ@28221|Deltaproteobacteria,2Z0CD@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
TLS3_k127_8134845_5	290397.Adeh_2054	1.402e-108	359.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,42P4T@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	AsmA family	asmA	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
TLS3_k127_8144840_0	404589.Anae109_1525	1.472e-301	931.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria,2YTZV@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
TLS3_k127_8144840_1	290397.Adeh_2349	4.352e-270	836.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2WJ5H@28221|Deltaproteobacteria,2YUG2@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
TLS3_k127_8144840_8	290397.Adeh_2351	1.129e-91	310.0	COG0586@1|root,COG0586@2|Bacteria,1R6V4@1224|Proteobacteria,42XP4@68525|delta/epsilon subdivisions,2WT5P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
TLS3_k127_8144840_10	290397.Adeh_2352	5.254e-33	136.0	COG0664@1|root,COG0664@2|Bacteria,1RDKD@1224|Proteobacteria	1224|Proteobacteria	T	PFAM Cyclic nucleotide-binding	MA20_24885	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
TLS3_k127_8144840_9	290397.Adeh_2353	1.005e-66	239.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,42MR0@68525|delta/epsilon subdivisions,2WP23@28221|Deltaproteobacteria,2Z0GF@29|Myxococcales	28221|Deltaproteobacteria	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep
TLS3_k127_8144840_11	290397.Adeh_2354	1.547e-16	94.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
TLS3_k127_8144840_2	404589.Anae109_1518	3.122e-217	682.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2WJEE@28221|Deltaproteobacteria,2YUPE@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
TLS3_k127_8144840_4	404589.Anae109_1513	7.227e-135	456.0	COG3552@1|root,COG3552@2|Bacteria,1MUHH@1224|Proteobacteria,42QBK@68525|delta/epsilon subdivisions,2WITZ@28221|Deltaproteobacteria,2YW16@29|Myxococcales	28221|Deltaproteobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
TLS3_k127_8144840_7	404589.Anae109_1011	2.302e-93	314.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,42KZF@68525|delta/epsilon subdivisions,2WSRV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_8144840_6	290397.Adeh_3385	4.682e-117	400.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,42YKP@68525|delta/epsilon subdivisions,2WUQ9@28221|Deltaproteobacteria,2YWFW@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K02056,ko:K05776,ko:K10441,ko:K10539,ko:K10542,ko:K10545,ko:K10548	ko02010,map02010	M00189,M00212,M00213,M00214,M00215,M00216,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.2,3.A.1.2.3,3.A.1.2.4,3.A.1.2.5	-	-	ABC_tran
TLS3_k127_8144840_3	404589.Anae109_1511	1.38e-164	531.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2WKJ2@28221|Deltaproteobacteria,2Z11I@29|Myxococcales	28221|Deltaproteobacteria	M	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
TLS3_k127_8147231_1	1123504.JQKD01000012_gene1267	5.145e-65	228.0	COG0412@1|root,COG0412@2|Bacteria,1MW88@1224|Proteobacteria,2VQD1@28216|Betaproteobacteria,4AJAF@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
TLS3_k127_8147231_0	448385.sce1977	2.145e-226	721.0	28MSW@1|root,2ZB15@2|Bacteria,1PSQ1@1224|Proteobacteria,438W7@68525|delta/epsilon subdivisions,2X41R@28221|Deltaproteobacteria,2YXZ7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8159810_7	404589.Anae109_0050	9.31e-93	307.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42M3T@68525|delta/epsilon subdivisions,2WIV8@28221|Deltaproteobacteria,2YUPZ@29|Myxococcales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
TLS3_k127_8159810_4	290397.Adeh_0050	5.488e-125	418.0	COG0491@1|root,COG0491@2|Bacteria,1MUXF@1224|Proteobacteria,42QER@68525|delta/epsilon subdivisions,2WM9B@28221|Deltaproteobacteria,2Z2AM@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_8159810_5	404589.Anae109_0052	1.209e-110	363.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria,2YUTH@29|Myxococcales	28221|Deltaproteobacteria	P	Membrane protein, TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
TLS3_k127_8159810_6	404589.Anae109_0053	7.497e-98	327.0	COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,42NW9@68525|delta/epsilon subdivisions,2WJEJ@28221|Deltaproteobacteria,2YXIG@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_8159810_2	404589.Anae109_0057	3.519e-142	459.0	COG1236@1|root,COG1236@2|Bacteria,1MV7U@1224|Proteobacteria	1224|Proteobacteria	J	Exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
TLS3_k127_8159810_3	290397.Adeh_0056	1.809e-140	459.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,430SK@68525|delta/epsilon subdivisions,2WW4G@28221|Deltaproteobacteria,2Z323@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
TLS3_k127_8159810_0	290397.Adeh_0057	0.0	1128.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2YYWB@29|Myxococcales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
TLS3_k127_8159810_1	290397.Adeh_0058	2.301e-248	785.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,2YU4H@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	rppA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
TLS3_k127_8159810_8	290397.Adeh_0059	2.613e-67	232.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria	1224|Proteobacteria	S	Ubiquinol-cytochrome C reductase	MA20_25125	-	-	-	-	-	-	-	-	-	-	-	EVE
TLS3_k127_8159810_9	404589.Anae109_0062	1.871e-25	109.0	COG1826@1|root,COG1826@2|Bacteria,1PJQP@1224|Proteobacteria,4358S@68525|delta/epsilon subdivisions,2WZJX@28221|Deltaproteobacteria,2Z2A9@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	-	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
TLS3_k127_8187163_0	404589.Anae109_1988	1.147e-317	978.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria,2YU4T@29|Myxococcales	28221|Deltaproteobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
TLS3_k127_8187163_2	290397.Adeh_1832	5.452e-69	235.0	COG2185@1|root,COG2185@2|Bacteria,1RKGS@1224|Proteobacteria,42SKV@68525|delta/epsilon subdivisions,2WP2X@28221|Deltaproteobacteria,2YV7A@29|Myxococcales	28221|Deltaproteobacteria	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
TLS3_k127_8187163_1	404589.Anae109_2166	2.101e-91	305.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,42Q6T@68525|delta/epsilon subdivisions,2WIN1@28221|Deltaproteobacteria,2Z2XK@29|Myxococcales	28221|Deltaproteobacteria	E	HMGL-like	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
TLS3_k127_8259482_3	404589.Anae109_2278	7.586e-58	203.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,43C2Q@68525|delta/epsilon subdivisions,2WSJ0@28221|Deltaproteobacteria,2YVH1@29|Myxococcales	28221|Deltaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
TLS3_k127_8259482_1	404589.Anae109_2277	6.833e-238	744.0	COG1260@1|root,COG1260@2|Bacteria,1N0D9@1224|Proteobacteria,42NWK@68525|delta/epsilon subdivisions,2WM2T@28221|Deltaproteobacteria,2YYFZ@29|Myxococcales	28221|Deltaproteobacteria	I	synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
TLS3_k127_8259482_0	290397.Adeh_1536	1.951e-252	800.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria	290397.Adeh_1536|-	O	Heat shock 70 kDa protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8259482_5	290397.Adeh_1537	1.018e-25	121.0	COG2210@1|root,COG2210@2|Bacteria	2|Bacteria	P	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,DrsE_2
TLS3_k127_8259482_2	404589.Anae109_2275	4.169e-90	305.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,42NEC@68525|delta/epsilon subdivisions,2WK08@28221|Deltaproteobacteria,2YUA5@29|Myxococcales	28221|Deltaproteobacteria	HP	domain protein	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
TLS3_k127_8259482_6	290397.Adeh_1539	2.571e-16	93.0	COG0425@1|root,COG0425@2|Bacteria,1NGCU@1224|Proteobacteria,42XTE@68525|delta/epsilon subdivisions,2WSIH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	tusA-1	-	-	-	-	-	-	-	-	-	-	-	TusA
TLS3_k127_8259482_4	290397.Adeh_1540	2.41e-42	170.0	COG0476@1|root,COG0476@2|Bacteria,1PDDQ@1224|Proteobacteria,435G7@68525|delta/epsilon subdivisions,2WZTP@28221|Deltaproteobacteria,2Z2QN@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
TLS3_k127_8272693_2	449447.MAE_01080	5.815e-19	104.0	COG1905@1|root,COG1905@2|Bacteria,1G54V@1117|Cyanobacteria	1117|Cyanobacteria	C	PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit	hoxE	-	1.6.5.3	ko:K05586	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx
TLS3_k127_8272693_0	1254432.SCE1572_31285	0.0	1162.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X791@28221|Deltaproteobacteria,2YUF6@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
TLS3_k127_8272693_1	290397.Adeh_0444	3.471e-50	181.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42N9C@68525|delta/epsilon subdivisions,2WJ2J@28221|Deltaproteobacteria,2YXSZ@29|Myxococcales	28221|Deltaproteobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
TLS3_k127_8273769_2	404589.Anae109_2111	4.258e-28	123.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria,2Z0ST@29|Myxococcales	28221|Deltaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,TPR_6
TLS3_k127_8273769_1	404589.Anae109_2110	4.559e-94	326.0	COG3155@1|root,COG3155@2|Bacteria,1MW2K@1224|Proteobacteria,42R54@68525|delta/epsilon subdivisions,2WMNZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM ThiJ PfpI domain protein	elbB	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
TLS3_k127_8273769_3	404589.Anae109_2109	9.053e-27	113.0	2DYE1@1|root,349AP@2|Bacteria,1NZTB@1224|Proteobacteria	1224|Proteobacteria	C	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
TLS3_k127_8273769_0	290397.Adeh_1698	0.0	1251.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,2YTZJ@29|Myxococcales	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
TLS3_k127_8273769_4	404589.Anae109_0082	3.106e-24	103.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	peptidase, M16	MA20_05660	-	-	ko:K07263,ko:K07623	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_8305829_2	290397.Adeh_4186	5.648e-55	218.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,42MJ2@68525|delta/epsilon subdivisions,2WJQB@28221|Deltaproteobacteria,2YUP1@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0072	IF-2B
TLS3_k127_8305829_0	404589.Anae109_4336	4.244e-244	773.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,2YUCW@29|Myxococcales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
TLS3_k127_8305829_1	290397.Adeh_4188	1.045e-219	686.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2YTXJ@29|Myxococcales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
TLS3_k127_8314161_1	404589.Anae109_3346	4.046e-198	628.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,42YBA@68525|delta/epsilon subdivisions,2WUP5@28221|Deltaproteobacteria,2YX31@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase, M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
TLS3_k127_8314161_0	404589.Anae109_3343	1.449e-202	638.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2WJRH@28221|Deltaproteobacteria,2YUPB@29|Myxococcales	28221|Deltaproteobacteria	E	Aminopeptidase P, N-terminal domain	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
TLS3_k127_8314161_2	290397.Adeh_1438	1.42e-124	403.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,42MJI@68525|delta/epsilon subdivisions,2WJQP@28221|Deltaproteobacteria,2YYGI@29|Myxococcales	28221|Deltaproteobacteria	C	6-phosphogluconate dehydrogenase, C-terminal domain	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2620	6PGD,NAD_binding_2
TLS3_k127_832384_2	404589.Anae109_1953	2.492e-27	120.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WPM9@28221|Deltaproteobacteria,2YV6T@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	mltE	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_19,TPR_6,TPR_8
TLS3_k127_832384_0	404589.Anae109_1952	5e-324	1006.0	COG2203@1|root,COG3852@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,43BPS@68525|delta/epsilon subdivisions,2X710@28221|Deltaproteobacteria,2YU4V@29|Myxococcales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
TLS3_k127_832384_1	502025.Hoch_2510	1.509e-158	512.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YU4Y@29|Myxococcales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_8326036_3	290397.Adeh_3766	1.056e-89	300.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2WJJG@28221|Deltaproteobacteria,2YU1E@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_8326036_0	404589.Anae109_3878	1.292e-204	664.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,2YTT3@29|Myxococcales	28221|Deltaproteobacteria	M	penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
TLS3_k127_8326036_6	290397.Adeh_3764	6.872e-12	78.0	COG3116@1|root,COG3116@2|Bacteria	2|Bacteria	D	cell division	ftsL	GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
TLS3_k127_8326036_1	404589.Anae109_3876	3.223e-145	471.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2WJ8J@28221|Deltaproteobacteria,2YUXX@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
TLS3_k127_8326036_4	290397.Adeh_3761	8.412e-49	179.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,42TRZ@68525|delta/epsilon subdivisions,2WQRI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
TLS3_k127_8326036_2	404589.Anae109_3873	2.649e-119	389.0	COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,42YTV@68525|delta/epsilon subdivisions,2WTY1@28221|Deltaproteobacteria,2YYJ0@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short
TLS3_k127_832720_5	290397.Adeh_3945	4.495e-51	183.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2WMJ5@28221|Deltaproteobacteria,2YV59@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
TLS3_k127_832720_2	290397.Adeh_3990	9.041e-102	344.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42RAB@68525|delta/epsilon subdivisions,2X5MA@28221|Deltaproteobacteria,2Z369@29|Myxococcales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
TLS3_k127_832720_4	404589.Anae109_1741	1.512e-79	279.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,42RNH@68525|delta/epsilon subdivisions,2X5NY@28221|Deltaproteobacteria,2Z0TQ@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	-	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
TLS3_k127_832720_3	290397.Adeh_3940	3.591e-85	293.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,42TQG@68525|delta/epsilon subdivisions,2WQG8@28221|Deltaproteobacteria,2YW3V@29|Myxococcales	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
TLS3_k127_832720_1	290397.Adeh_3939	7.474e-109	360.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42QU3@68525|delta/epsilon subdivisions,2WMTF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_832720_0	290397.Adeh_3938	5.267e-262	838.0	COG0577@1|root,COG0577@2|Bacteria,1RC4T@1224|Proteobacteria,42QZ6@68525|delta/epsilon subdivisions,2WMU4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
TLS3_k127_832720_6	290397.Adeh_3937	1.534e-33	150.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42NUK@68525|delta/epsilon subdivisions,2WJTJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_8331288_0	404589.Anae109_2220	0.0	1171.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2YUJI@29|Myxococcales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
TLS3_k127_8331288_2	290397.Adeh_1594	1.101e-141	452.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
TLS3_k127_8331288_9	1303518.CCALI_01243	6.188e-09	65.0	COG1317@1|root,COG1317@2|Bacteria	2|Bacteria	N	bacterial-type flagellum organization	fliH	-	-	ko:K02411,ko:K03223	ko02040,ko03070,map02040,map03070	M00332,M00660	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	FliH
TLS3_k127_8331288_1	290397.Adeh_1596	2.025e-161	531.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,42M0K@68525|delta/epsilon subdivisions,2WISR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PFAM H transporting two-sector ATPase alpha beta subunit central region	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
TLS3_k127_8331288_7	290397.Adeh_1598	4.082e-34	136.0	COG0745@1|root,COG0745@2|Bacteria	290397.Adeh_1598|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8331288_5	404589.Anae109_2213	2.769e-82	291.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,2YZS6@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TLS3_k127_8331288_4	290397.Adeh_1601	8.625e-102	345.0	COG2313@1|root,COG2313@2|Bacteria,1MUQU@1224|Proteobacteria,42ZS4@68525|delta/epsilon subdivisions,2WV20@28221|Deltaproteobacteria,2YUUK@29|Myxococcales	28221|Deltaproteobacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
TLS3_k127_8331288_3	290397.Adeh_1602	2.965e-117	386.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,42N0J@68525|delta/epsilon subdivisions,2WJFX@28221|Deltaproteobacteria,2YVNW@29|Myxococcales	28221|Deltaproteobacteria	J	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
TLS3_k127_8331288_6	290397.Adeh_1603	2.02e-70	248.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	transglycosylase	slt	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	iETEC_1333.ETEC_4747,iPC815.YPO0452	SLT,SLT_L
TLS3_k127_8334017_2	290397.Adeh_0295	6.658e-59	206.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,42QF3@68525|delta/epsilon subdivisions,2WKPQ@28221|Deltaproteobacteria,2YYXT@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	6.1.1.17	ko:K01885,ko:K01894	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
TLS3_k127_8334017_1	404589.Anae109_0318	2.177e-218	695.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,42PZB@68525|delta/epsilon subdivisions,2WK77@28221|Deltaproteobacteria,2YVA7@29|Myxococcales	28221|Deltaproteobacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
TLS3_k127_8334017_0	404589.Anae109_0317	0.0	1263.0	COG3280@1|root,COG3280@2|Bacteria,1QTVK@1224|Proteobacteria,42MEW@68525|delta/epsilon subdivisions,2WJX1@28221|Deltaproteobacteria,2YUMZ@29|Myxococcales	28221|Deltaproteobacteria	G	Alpha amylase, catalytic domain	treY	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
TLS3_k127_83668_7	404589.Anae109_2085	8.815e-120	404.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,42YFC@68525|delta/epsilon subdivisions,2WU03@28221|Deltaproteobacteria,2YUBP@29|Myxococcales	28221|Deltaproteobacteria	I	desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_83668_19	290397.Adeh_1719	2.592e-38	161.0	COG2010@1|root,COG3915@1|root,COG2010@2|Bacteria,COG3915@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,Oxidored_molyb
TLS3_k127_83668_9	404589.Anae109_2081	1.19e-86	298.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,42R50@68525|delta/epsilon subdivisions,2X3AE@28221|Deltaproteobacteria,2YV4E@29|Myxococcales	28221|Deltaproteobacteria	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
TLS3_k127_83668_13	404589.Anae109_2080	7.409e-69	247.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WN3N@28221|Deltaproteobacteria,2YVHP@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
TLS3_k127_83668_2	290397.Adeh_1723	2.358e-225	720.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2YTVW@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_83668_3	290397.Adeh_1724	3.412e-193	611.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2WJ4D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	yfdZ	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_83668_17	935863.AWZR01000007_gene259	2.292e-60	215.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1X3XJ@135614|Xanthomonadales	1236|Gammaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
TLS3_k127_83668_1	404589.Anae109_2074	0.0	1122.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2WKBA@28221|Deltaproteobacteria,2YXV4@29|Myxococcales	28221|Deltaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
TLS3_k127_83668_14	404589.Anae109_2073	1.039e-67	238.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2WP41@28221|Deltaproteobacteria,2YV5G@29|Myxococcales	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
TLS3_k127_83668_0	290397.Adeh_1729	0.0	1784.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria,2YUKG@29|Myxococcales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
TLS3_k127_83668_5	1278073.MYSTI_04546	2.912e-123	411.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria,2YU6F@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_83668_12	290397.Adeh_1732	6.77e-69	237.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,2YYUB@29|Myxococcales	28221|Deltaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
TLS3_k127_83668_11	404589.Anae109_2064	5.756e-70	257.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2WWMK@28221|Deltaproteobacteria,2Z2ZS@29|Myxococcales	28221|Deltaproteobacteria	L	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
TLS3_k127_83668_4	404589.Anae109_2062	2.741e-124	409.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2WMDZ@28221|Deltaproteobacteria,2YV35@29|Myxococcales	28221|Deltaproteobacteria	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
TLS3_k127_83668_8	404589.Anae109_2061	3.751e-99	335.0	COG2267@1|root,COG2267@2|Bacteria,1QX85@1224|Proteobacteria,42W1M@68525|delta/epsilon subdivisions,2WR6V@28221|Deltaproteobacteria,2YUZN@29|Myxococcales	28221|Deltaproteobacteria	I	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
TLS3_k127_83668_18	379731.PST_3897	1.614e-46	173.0	COG2716@1|root,COG2716@2|Bacteria,1MZJ6@1224|Proteobacteria,1S764@1236|Gammaproteobacteria,1YZX2@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	E	Glycine cleavage system regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT_4,ACT_6
TLS3_k127_83668_23	697282.Mettu_0159	1.212e-14	84.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Glutaredoxin
TLS3_k127_83668_10	404589.Anae109_1699	6.54e-78	264.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,42SKB@68525|delta/epsilon subdivisions,2WQ2K@28221|Deltaproteobacteria,2YV8W@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
TLS3_k127_83668_6	179408.Osc7112_1634	2.001e-122	398.0	COG0121@1|root,COG0121@2|Bacteria,1G101@1117|Cyanobacteria,1H94N@1150|Oscillatoriales	1117|Cyanobacteria	S	Glutamine amidotransferases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
TLS3_k127_83668_25	215803.DB30_5351	2.575e-10	71.0	COG3591@1|root,COG3591@2|Bacteria,1QX7V@1224|Proteobacteria,43C0V@68525|delta/epsilon subdivisions,2X7BH@28221|Deltaproteobacteria,2YV6V@29|Myxococcales	28221|Deltaproteobacteria	E	Lysyl oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Lysyl_oxidase
TLS3_k127_8378241_2	290397.Adeh_0104	2.701e-124	421.0	COG2887@1|root,COG2887@2|Bacteria	2|Bacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD3	-	-	-	-	-	-	-	-	-	-	-	AAA_19,PDDEXK_1,UvrD-helicase,UvrD_C
TLS3_k127_8378241_3	794903.OPIT5_16195	3.269e-46	179.0	COG2253@1|root,COG2253@2|Bacteria	2|Bacteria	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
TLS3_k127_8378241_0	404589.Anae109_0252	8.218e-161	518.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,42MX0@68525|delta/epsilon subdivisions,2WM16@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM Multi antimicrobial extrusion protein MatE	norM-2	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
TLS3_k127_8378241_1	290397.Adeh_0103	6.465e-151	498.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,43A0V@68525|delta/epsilon subdivisions,2X9Q9@28221|Deltaproteobacteria,2Z07V@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_8378241_4	290397.Adeh_0102	1.081e-36	143.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42PZF@68525|delta/epsilon subdivisions,2X5HR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_8423974_3	232721.Ajs_1641	0.0004985	49.0	COG0745@1|root,COG0745@2|Bacteria,1R4GB@1224|Proteobacteria,2VJDU@28216|Betaproteobacteria,4AC6K@80864|Comamonadaceae	28216|Betaproteobacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07774	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_8423974_0	1254432.SCE1572_13135	1.966e-136	450.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,43B4D@68525|delta/epsilon subdivisions,2WKC8@28221|Deltaproteobacteria,2YX3N@29|Myxococcales	28221|Deltaproteobacteria	G	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
TLS3_k127_8423974_2	246197.MXAN_4687	3.782e-18	87.0	COG3350@1|root,COG3350@2|Bacteria	2|Bacteria	T	monooxygenase activity	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DUF2318,YHS
TLS3_k127_8423974_1	290397.Adeh_2533	9.166e-94	309.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2WJEV@28221|Deltaproteobacteria,2YTWY@29|Myxococcales	28221|Deltaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
TLS3_k127_8499438_6	290397.Adeh_1461	4.521e-28	130.0	COG2350@1|root,COG2350@2|Bacteria,1MZ8Y@1224|Proteobacteria,431ZT@68525|delta/epsilon subdivisions,2WWQ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
TLS3_k127_8499438_1	404589.Anae109_2686	3.951e-189	604.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2WIMW@28221|Deltaproteobacteria,2YTVG@29|Myxococcales	28221|Deltaproteobacteria	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_0204	Aminotran_3
TLS3_k127_8499438_2	290397.Adeh_2691	2.448e-144	482.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2WJ3G@28221|Deltaproteobacteria,2YUVY@29|Myxococcales	28221|Deltaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
TLS3_k127_8499438_3	290397.Adeh_2690	3.522e-78	272.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,TPR_8
TLS3_k127_8499438_0	290397.Adeh_2689	1.02e-261	835.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2YTUT@29|Myxococcales	28221|Deltaproteobacteria	O	heat shock protein 70	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
TLS3_k127_8499438_5	290397.Adeh_2688	3.413e-48	199.0	2DHU7@1|root,300Z2@2|Bacteria,1Q940@1224|Proteobacteria,433U6@68525|delta/epsilon subdivisions,2X3GR@28221|Deltaproteobacteria,2YW0V@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14
TLS3_k127_8499438_4	404589.Anae109_2678	1.172e-51	187.0	COG2030@1|root,COG2030@2|Bacteria,1NPDF@1224|Proteobacteria	1224|Proteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
TLS3_k127_858220_5	290397.Adeh_2651	3.246e-29	119.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42Y98@68525|delta/epsilon subdivisions,2WTXU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_858220_2	404589.Anae109_2618	3.517e-75	260.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42SP0@68525|delta/epsilon subdivisions,2WNYF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Polysaccharide export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
TLS3_k127_858220_1	404589.Anae109_2616	1.93e-146	477.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,42PYQ@68525|delta/epsilon subdivisions,2WKRC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TIGRFAM polysaccharide chain length determinant protein, PEP-CTERM locus subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_858220_3	404589.Anae109_2615	3.884e-70	244.0	COG0489@1|root,COG0489@2|Bacteria	2|Bacteria	D	protein tyrosine kinase activity	-	-	2.7.10.2	ko:K08253,ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
TLS3_k127_858220_0	404589.Anae109_2614	6.098e-180	574.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42NH8@68525|delta/epsilon subdivisions,2WJMA@28221|Deltaproteobacteria,2YV6H@29|Myxococcales	28221|Deltaproteobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
TLS3_k127_866673_2	1125863.JAFN01000001_gene746	3.687e-107	361.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42Y98@68525|delta/epsilon subdivisions,2WTXU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_866673_4	290397.Adeh_2652	9.988e-26	117.0	COG0607@1|root,COG0607@2|Bacteria,1PEZQ@1224|Proteobacteria,42X5U@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS3_k127_866673_0	290397.Adeh_2653	8.184e-169	551.0	COG2385@1|root,COG2385@2|Bacteria,1RGJS@1224|Proteobacteria,42RZE@68525|delta/epsilon subdivisions,2WNH8@28221|Deltaproteobacteria,2YTWF@29|Myxococcales	28221|Deltaproteobacteria	D	Stage II sporulation protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIID
TLS3_k127_866673_1	404589.Anae109_2639	4.948e-114	380.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WQC6@28221|Deltaproteobacteria,2YV64@29|Myxococcales	28221|Deltaproteobacteria	EH	Aminotransferase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_866673_5	1274374.CBLK010000024_gene2695	6.892e-21	99.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli,26RDD@186822|Paenibacillaceae	91061|Bacilli	T	PhoB family transcriptional regulator	ykoG	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_87089_0	290397.Adeh_0218	1.068e-264	820.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria,2Z2NY@29|Myxococcales	28221|Deltaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	poR	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
TLS3_k127_87089_2	290397.Adeh_0297	1.655e-139	473.0	COG2204@1|root,COG3452@1|root,COG4191@1|root,COG2204@2|Bacteria,COG3452@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2YZ7J@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
TLS3_k127_87089_3	404589.Anae109_0228	7.834e-53	192.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,42VN5@68525|delta/epsilon subdivisions,2WRGG@28221|Deltaproteobacteria,2YVQW@29|Myxococcales	28221|Deltaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
TLS3_k127_87089_1	290397.Adeh_0212	1.728e-202	638.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,42ME0@68525|delta/epsilon subdivisions,2WJB8@28221|Deltaproteobacteria,2YU1V@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_87089_4	290397.Adeh_0211	3.02e-36	138.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2WIVS@28221|Deltaproteobacteria,2YTY2@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3198	AA_kinase,PUA
TLS3_k127_883660_3	1192868.CAIU01000021_gene3067	8.363e-13	78.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TU0K@28211|Alphaproteobacteria,43HE3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_883660_2	1242864.D187_006529	1.071e-61	224.0	COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,42S16@68525|delta/epsilon subdivisions,2WNEY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
TLS3_k127_883660_0	404589.Anae109_0951	1.145e-165	528.0	COG1015@1|root,COG1015@2|Bacteria,1MVN8@1224|Proteobacteria,42NKQ@68525|delta/epsilon subdivisions,2WJVF@28221|Deltaproteobacteria,2YX5T@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
TLS3_k127_883660_1	404589.Anae109_2321	4.763e-108	359.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42RAB@68525|delta/epsilon subdivisions,2X5MA@28221|Deltaproteobacteria,2Z369@29|Myxococcales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
TLS3_k127_934736_9	290397.Adeh_0292	2.207e-21	96.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
TLS3_k127_934736_2	290397.Adeh_0291	1.783e-233	738.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,42MBU@68525|delta/epsilon subdivisions,2WIJP@28221|Deltaproteobacteria,2YWW6@29|Myxococcales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
TLS3_k127_934736_11	56107.Cylst_5841	2.907e-06	54.0	291AN@1|root,2ZNXN@2|Bacteria,1G5R7@1117|Cyanobacteria,1HNP2@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF1257)	ycf35	-	-	-	-	-	-	-	-	-	-	-	DUF1257
TLS3_k127_934736_13	502025.Hoch_3617	5.384e-05	48.0	2DU1D@1|root,33NHV@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2997)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2997
TLS3_k127_934736_0	290397.Adeh_0289	3.684e-308	956.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,2YUJ3@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
TLS3_k127_934736_8	290397.Adeh_0288	4.615e-53	191.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	citB	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	GerE
TLS3_k127_934736_6	404589.Anae109_0312	2.859e-66	250.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_6
TLS3_k127_934736_7	290397.Adeh_0286	1.078e-55	207.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	ko:K21009	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	GAF_3,GGDEF,PAS_4,Response_reg
TLS3_k127_934736_1	404589.Anae109_0311	1.56e-269	840.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria,2YWSD@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
TLS3_k127_934736_4	483219.LILAB_20935	4.462e-105	347.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,42M26@68525|delta/epsilon subdivisions,2WKQV@28221|Deltaproteobacteria,2Z331@29|Myxococcales	28221|Deltaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
TLS3_k127_934736_5	404589.Anae109_0305	8.927e-85	284.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2WNMN@28221|Deltaproteobacteria,2YV1Q@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
TLS3_k127_934736_3	290397.Adeh_0280	2.483e-135	433.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,2YU4R@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
TLS3_k127_938333_2	404589.Anae109_0913	3.731e-99	333.0	COG0265@1|root,COG0265@2|Bacteria,1N1NJ@1224|Proteobacteria	1224|Proteobacteria	O	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
TLS3_k127_938333_1	290397.Adeh_0855	1.232e-120	410.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
TLS3_k127_938333_7	469383.Cwoe_1069	1.516e-06	59.0	COG1670@1|root,COG1670@2|Bacteria,2GP87@201174|Actinobacteria,4CQI4@84995|Rubrobacteria	84995|Rubrobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TLS3_k127_938333_3	1242864.D187_001805	1.836e-70	250.0	COG2755@1|root,COG2755@2|Bacteria,1NAAJ@1224|Proteobacteria,432EF@68525|delta/epsilon subdivisions,2WY26@28221|Deltaproteobacteria,2YYAT@29|Myxococcales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
TLS3_k127_938333_6	404589.Anae109_2891	7.136e-27	111.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,42V9P@68525|delta/epsilon subdivisions,2X5QW@28221|Deltaproteobacteria,2Z1ZE@29|Myxococcales	28221|Deltaproteobacteria	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
TLS3_k127_938333_5	290397.Adeh_0510	7.892e-33	135.0	COG0782@1|root,COG0782@2|Bacteria,1MZNY@1224|Proteobacteria	1224|Proteobacteria	K	nucleoside diphosphate kinase	rnk	-	-	ko:K06140	-	-	-	-	ko00000,ko03000	-	-	-	GreA_GreB,Rnk_N
TLS3_k127_938333_0	404589.Anae109_1251	9.504e-186	600.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WN1C@28221|Deltaproteobacteria,2Z2Y2@29|Myxococcales	28221|Deltaproteobacteria	D	PFAM lipopolysaccharide biosynthesis protein	-	-	-	ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,GNVR,Wzz
TLS3_k127_952556_3	290397.Adeh_0676	1.319e-07	53.0	2DRH1@1|root,33BQ8@2|Bacteria,1NM8D@1224|Proteobacteria,42XND@68525|delta/epsilon subdivisions,2WSKN@28221|Deltaproteobacteria,2YW71@29|Myxococcales	28221|Deltaproteobacteria	-	-	gspN	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
TLS3_k127_952556_2	326427.Cagg_0170	1.736e-36	150.0	COG2267@1|root,COG2267@2|Bacteria,2GAN6@200795|Chloroflexi,376TU@32061|Chloroflexia	32061|Chloroflexia	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
TLS3_k127_952556_1	290397.Adeh_0675	7.327e-183	601.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
TLS3_k127_952556_0	290397.Adeh_0674	0.0	1691.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,2YU45@29|Myxococcales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
TLS3_k127_988659_1	404589.Anae109_1098	7.014e-138	467.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2YWNS@29|Myxococcales	28221|Deltaproteobacteria	H	Aminotransferase, class V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
TLS3_k127_988659_0	404589.Anae109_1099	2.491e-160	518.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
TLS3_k127_988659_2	290397.Adeh_1050	3.187e-131	425.0	COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,42MYE@68525|delta/epsilon subdivisions,2WJC7@28221|Deltaproteobacteria,2Z0QD@29|Myxococcales	28221|Deltaproteobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
TLS3_k127_988659_4	290397.Adeh_1051	4.55e-71	250.0	COG3177@1|root,COG3177@2|Bacteria,1Q2H9@1224|Proteobacteria,4383Y@68525|delta/epsilon subdivisions,2X3DX@28221|Deltaproteobacteria,2YVMK@29|Myxococcales	28221|Deltaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
TLS3_k127_988659_3	404589.Anae109_1102	7.623e-117	378.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2YV73@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_992023_2	290397.Adeh_1610	2.383e-45	173.0	COG0468@1|root,COG0468@2|Bacteria	2|Bacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360	-	ko:K03553,ko:K14160	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
TLS3_k127_992023_1	290397.Adeh_1611	3.636e-143	473.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria	1224|Proteobacteria	L	nucleotidyltransferase DNA polymerase involved in DNA repair	imuB	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
TLS3_k127_992023_0	290397.Adeh_1612	0.0	1512.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,42MYQ@68525|delta/epsilon subdivisions,2WJM2@28221|Deltaproteobacteria,2YTST@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
TLS3_k127_992023_3	246197.MXAN_5794	1.005e-16	86.0	COG4633@1|root,COG4633@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,DsbD_2,HMA
## 2618 queries scanned
## Total time (seconds): 115.84873485565186
## Rate: 22.60 q/s