## Thu Feb 19 20:01:16 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/TLS3_bin.38.fa -m mmseqs --output TLS3_bin.38 --output_dir /data/result/bins/wyx/eggqs50+/TLS3_bin.38 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
TLS3_k127_1006505_5	1237149.C900_01375	6.252e-73	254.0	COG3047@1|root,COG3047@2|Bacteria,4NMXC@976|Bacteroidetes,47PJK@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_1006505_1	1237149.C900_01374	6.358e-112	374.0	2C85B@1|root,2ZAAM@2|Bacteria,4NKNU@976|Bacteroidetes,47P2W@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1006505_0	929562.Emtol_2295	3.259e-120	394.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,47KJJ@768503|Cytophagia	976|Bacteroidetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
TLS3_k127_1006505_3	1237149.C900_02480	5.902e-86	287.0	COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,47P6P@768503|Cytophagia	976|Bacteroidetes	F	PFAM Cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
TLS3_k127_1006505_6	1237149.C900_02479	1.071e-60	214.0	COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,47XP3@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
TLS3_k127_1006505_7	1237149.C900_02061	2.353e-32	132.0	2DGJ8@1|root,2ZW7H@2|Bacteria,4P7SP@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1006505_2	1408473.JHXO01000011_gene3211	1.409e-94	316.0	COG2010@1|root,COG2010@2|Bacteria,4PPMX@976|Bacteroidetes	976|Bacteroidetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_1006505_8	1348114.OM33_09020	1.82e-18	91.0	COG3126@1|root,COG3187@1|root,COG3126@2|Bacteria,COG3187@2|Bacteria,1N9XV@1224|Proteobacteria,1S4T0@1236|Gammaproteobacteria,2Q2E3@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	O	Type III secretion system lipoprotein chaperone (YscW)	-	-	-	ko:K09914	-	-	-	-	ko00000	-	-	-	META,NlpE,NlpE_C,YscW
TLS3_k127_1006505_4	1237149.C900_05162	4.331e-82	280.0	COG0682@1|root,COG0682@2|Bacteria	2|Bacteria	M	lipoprotein biosynthetic process	lgt_2	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
TLS3_k127_1015470_2	1123248.KB893338_gene2304	9.573e-35	136.0	COG3595@1|root,COG3595@2|Bacteria,4NJCC@976|Bacteroidetes,1IRTV@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
TLS3_k127_1015470_0	1237149.C900_03907	0.0	1118.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_1015470_1	643867.Ftrac_1034	2.642e-35	151.0	COG4796@1|root,COG4796@2|Bacteria	2|Bacteria	U	Type ii and iii secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,DUF4974,Plug,STN,TonB_dep_Rec
TLS3_k127_1015575_8	1122983.BAJY01000008_gene1552	5.929e-17	81.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FXTE@200643|Bacteroidia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
TLS3_k127_1015575_5	1120966.AUBU01000002_gene1922	4.652e-65	226.0	COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,47JGP@768503|Cytophagia	976|Bacteroidetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
TLS3_k127_1015575_1	153721.MYP_4168	1.753e-111	363.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,47JJZ@768503|Cytophagia	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
TLS3_k127_1015575_4	1237149.C900_04671	1.397e-78	263.0	COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,47PEZ@768503|Cytophagia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
TLS3_k127_1015575_2	1237149.C900_04670	5.675e-105	342.0	COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,47KBF@768503|Cytophagia	976|Bacteroidetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
TLS3_k127_1015575_7	1237149.C900_04669	3.958e-22	96.0	COG0690@1|root,COG0690@2|Bacteria,4NX53@976|Bacteroidetes,47RVC@768503|Cytophagia	976|Bacteroidetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
TLS3_k127_1015575_0	643867.Ftrac_3018	1.405e-229	713.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,47JYT@768503|Cytophagia	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
TLS3_k127_1015575_12	1236518.BAKP01000026_gene1675	0.0002323	46.0	2DD50@1|root,2ZGIJ@2|Bacteria,4P8A2@976|Bacteroidetes,2FZIU@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1015575_9	1158294.JOMI01000009_gene919	1.792e-06	50.0	2DR8D@1|root,33ANQ@2|Bacteria,4NYGG@976|Bacteroidetes,2FVPJ@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1015575_6	1124780.ANNU01000006_gene2887	2.365e-26	110.0	COG5512@1|root,COG5512@2|Bacteria,4NXIK@976|Bacteroidetes,47S8C@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
TLS3_k127_1015575_3	313606.M23134_03685	9.114e-85	289.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,47JMB@768503|Cytophagia	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
TLS3_k127_1020573_0	1123248.KB893330_gene411	2.331e-108	353.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1IPWF@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
TLS3_k127_1020573_1	1123248.KB893314_gene3298	9.189e-92	307.0	COG1940@1|root,COG1940@2|Bacteria,4NFNR@976|Bacteroidetes,1IRJC@117747|Sphingobacteriia	976|Bacteroidetes	GK	ROK family	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
TLS3_k127_1048157_3	1124780.ANNU01000008_gene2648	1.215e-46	175.0	COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,47MRD@768503|Cytophagia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
TLS3_k127_1048157_1	929562.Emtol_0842	2.178e-89	302.0	COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,47NIJ@768503|Cytophagia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
TLS3_k127_1048157_2	1124780.ANNU01000008_gene2646	1.756e-88	298.0	COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,47K33@768503|Cytophagia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
TLS3_k127_1048157_0	700598.Niako_5849	5.994e-134	436.0	COG3569@1|root,COG3569@2|Bacteria,4NGTF@976|Bacteroidetes,1IPJC@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
TLS3_k127_1048157_4	1122605.KB893643_gene597	8.708e-28	116.0	2DJ8B@1|root,32UCJ@2|Bacteria,4NTR0@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1051499_1	760192.Halhy_4520	3.069e-174	559.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1IRNW@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_1051499_2	926549.KI421517_gene931	5.745e-171	554.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,47MIN@768503|Cytophagia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
TLS3_k127_1051499_0	760192.Halhy_4423	1.229e-195	621.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.22.37,3.5.3.12	ko:K08589,ko:K10536	ko00330,ko01100,ko01503,map00330,map01100,map01503	-	R01416	RC00177	ko00000,ko00001,ko01000,ko01002	-	-	-	PAD_porph,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
TLS3_k127_1055361_1	273121.WS2190	1.56e-69	249.0	COG0438@1|root,COG0438@2|Bacteria,1N57K@1224|Proteobacteria,42Z80@68525|delta/epsilon subdivisions,2YRKI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
TLS3_k127_1055361_3	926562.Oweho_1386	7.569e-45	185.0	COG3291@1|root,COG3621@1|root,COG3291@2|Bacteria,COG3621@2|Bacteria,4P4YJ@976|Bacteroidetes	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
TLS3_k127_1055361_4	1124780.ANNU01000045_gene2325	4.84e-33	133.0	COG3386@1|root,COG3386@2|Bacteria,4PM2F@976|Bacteroidetes,47Y09@768503|Cytophagia	976|Bacteroidetes	G	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_1055361_0	1237149.C900_04808	1.55e-87	292.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,47PA6@768503|Cytophagia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
TLS3_k127_1055361_2	1123278.KB893522_gene2515	9.626e-54	201.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,47KYN@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_1067240_0	929703.KE386491_gene3976	1.037e-218	685.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,47KR9@768503|Cytophagia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TLS3_k127_1067240_2	1120965.AUBV01000008_gene2105	2.879e-22	98.0	2E5GR@1|root,3308C@2|Bacteria,4NUPC@976|Bacteroidetes,47S69@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1067240_1	1237149.C900_00373	1.139e-107	352.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,47K4M@768503|Cytophagia	976|Bacteroidetes	S	PFAM MazG nucleotide pyrophosphohydrolase	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
TLS3_k127_1071286_0	1237149.C900_05563	1.992e-156	502.0	COG1680@1|root,COG1680@2|Bacteria,4NER1@976|Bacteroidetes,47M8G@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
TLS3_k127_1071286_5	1237149.C900_05564	5.681e-64	224.0	2D9XB@1|root,32TU6@2|Bacteria,4NSXG@976|Bacteroidetes,47R3J@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1071286_1	1237149.C900_05565	2.921e-109	360.0	COG3279@1|root,COG3279@2|Bacteria,4NP0E@976|Bacteroidetes,47Q29@768503|Cytophagia	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
TLS3_k127_1071286_3	743722.Sph21_2105	2.826e-74	254.0	COG0664@1|root,COG0664@2|Bacteria,4NNEC@976|Bacteroidetes,1J0B3@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
TLS3_k127_1071286_6	468059.AUHA01000002_gene130	4.093e-59	206.0	COG0494@1|root,COG0494@2|Bacteria,4NR26@976|Bacteroidetes,1IT13@117747|Sphingobacteriia	976|Bacteroidetes	L	nUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1071286_10	675817.VDA_001735	1.945e-06	55.0	2BY4F@1|root,333PG@2|Bacteria,1QJW6@1224|Proteobacteria,1THXV@1236|Gammaproteobacteria,1XXV2@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1071286_8	1380600.AUYN01000003_gene155	6.485e-20	93.0	2EB7H@1|root,33583@2|Bacteria,4NUPY@976|Bacteroidetes,1IBH8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1071286_9	298655.KI912266_gene5017	1.073e-10	68.0	2CAP7@1|root,33DEX@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1772)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1772
TLS3_k127_1071286_7	1123277.KB893173_gene1693	5.734e-43	168.0	COG2135@1|root,COG2135@2|Bacteria,4NI3T@976|Bacteroidetes,47XPZ@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the SOS response-associated peptidase family	yoqW	-	-	-	-	-	-	-	-	-	-	-	SRAP
TLS3_k127_1071286_2	1341181.FLJC2902T_28220	2.629e-103	347.0	COG3266@1|root,COG3266@2|Bacteria,4NMES@976|Bacteroidetes,1HYRQ@117743|Flavobacteriia,2NTDD@237|Flavobacterium	976|Bacteroidetes	A	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1071286_4	1341181.FLJC2902T_28210	6.095e-66	229.0	COG4319@1|root,COG4319@2|Bacteria,4NRTT@976|Bacteroidetes,1I3HR@117743|Flavobacteriia,2NWDQ@237|Flavobacterium	976|Bacteroidetes	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
TLS3_k127_1073357_0	714943.Mucpa_5976	5.377e-139	450.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1IQ1A@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_1073357_5	1408473.JHXO01000002_gene3904	2.488e-20	97.0	2AU1F@1|root,31JMK@2|Bacteria,4NQUW@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1073357_4	1237149.C900_05273	2.552e-35	139.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,47QNS@768503|Cytophagia	976|Bacteroidetes	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
TLS3_k127_1073357_2	926549.KI421517_gene1175	4.374e-50	182.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,47R7Q@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
TLS3_k127_1073357_6	4565.Traes_3B_BC070E061.1	1.63e-09	66.0	COG0071@1|root,KOG0710@2759|Eukaryota,37TQV@33090|Viridiplantae,3GC1C@35493|Streptophyta,3KUTU@4447|Liliopsida,3I533@38820|Poales	35493|Streptophyta	O	Belongs to the small heat shock protein (HSP20) family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0044424,GO:0044464,GO:0050896	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
TLS3_k127_1073357_3	1144313.PMI10_03198	1.878e-36	140.0	COG5485@1|root,COG5485@2|Bacteria,4PA5J@976|Bacteroidetes,1IDNX@117743|Flavobacteriia,2NYVF@237|Flavobacterium	976|Bacteroidetes	S	Ester cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1073357_1	1144313.PMI10_03199	1.216e-84	287.0	COG2207@1|root,COG2207@2|Bacteria,4NHA5@976|Bacteroidetes,1IIVQ@117743|Flavobacteriia,2P0GI@237|Flavobacterium	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
TLS3_k127_1076712_0	1121481.AUAS01000001_gene4747	3.915e-143	463.0	COG2128@1|root,COG2128@2|Bacteria,4NHD5@976|Bacteroidetes,47M83@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
TLS3_k127_1076712_1	1123248.KB893333_gene2812	5.207e-66	231.0	COG2128@1|root,COG2128@2|Bacteria,4NNHK@976|Bacteroidetes,1IWPA@117747|Sphingobacteriia	976|Bacteroidetes	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
TLS3_k127_1076712_2	1123248.KB893333_gene2812	5.462e-58	203.0	COG2128@1|root,COG2128@2|Bacteria,4NNHK@976|Bacteroidetes,1IWPA@117747|Sphingobacteriia	976|Bacteroidetes	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
TLS3_k127_1082401_1	929703.KE386491_gene2866	2.324e-35	139.0	COG0135@1|root,COG0135@2|Bacteria,4NNQ1@976|Bacteroidetes,47N69@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
TLS3_k127_1082401_0	1237149.C900_03304	9.78e-213	665.0	COG0133@1|root,COG0133@2|Bacteria,4NDWP@976|Bacteroidetes,47KSV@768503|Cytophagia	976|Bacteroidetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_108567_3	1237149.C900_05454	4.291e-48	178.0	COG4886@1|root,COG4886@2|Bacteria,4NKMV@976|Bacteroidetes,47XBF@768503|Cytophagia	976|Bacteroidetes	S	Leucine-rich repeat (LRR) protein	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	COR,LRR_4,Roc,TIR_2
TLS3_k127_108567_1	1237149.C900_05455	1.308e-104	346.0	28Y2X@1|root,2ZJYG@2|Bacteria,4NN0R@976|Bacteroidetes,47PI8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_108567_2	1237149.C900_05456	1.344e-94	312.0	28N54@1|root,2ZBAD@2|Bacteria,4NM2U@976|Bacteroidetes,47JA1@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_108567_4	1237149.C900_05457	7.747e-47	175.0	2CD9I@1|root,32WZN@2|Bacteria,4NSXQ@976|Bacteroidetes,47R4I@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_108567_0	504472.Slin_0936	9.501e-232	733.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_1091315_1	1237149.C900_00284	8.12e-68	238.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,47PIA@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_1091315_0	1121373.KB903665_gene3134	2.255e-104	348.0	COG1230@1|root,COG1230@2|Bacteria,4NIHB@976|Bacteroidetes,47NNT@768503|Cytophagia	976|Bacteroidetes	P	Cation efflux family	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
TLS3_k127_1091315_2	1406840.Q763_12045	2.041e-51	185.0	COG2076@1|root,COG2076@2|Bacteria,4NQ4U@976|Bacteroidetes,1I2X4@117743|Flavobacteriia,2NWN9@237|Flavobacterium	976|Bacteroidetes	P	Cation transporter	sugE	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
TLS3_k127_1091315_3	1185876.BN8_04246	3.872e-05	46.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,47QER@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
TLS3_k127_1094941_1	526225.Gobs_0746	2.237e-31	140.0	COG1262@1|root,COG3170@1|root,COG1262@2|Bacteria,COG3170@2|Bacteria,2IBYZ@201174|Actinobacteria	201174|Actinobacteria	NU	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	PknH_C,TIR_2
TLS3_k127_1094941_4	1304865.JAGF01000001_gene1510	1.934e-11	68.0	2EGCD@1|root,33A46@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
TLS3_k127_1094941_0	1287276.X752_21155	7.284e-42	164.0	2DNDU@1|root,32X0Z@2|Bacteria,1NRWY@1224|Proteobacteria,2UYA8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1094941_3	1050202.KB913024_gene1095	1.892e-11	67.0	COG1479@1|root,COG3472@1|root,COG1479@2|Bacteria,COG3472@2|Bacteria,2IEWM@201174|Actinobacteria,407YJ@622450|Actinopolysporales	201174|Actinobacteria	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
TLS3_k127_109495_8	1237149.C900_01041	2.2e-19	89.0	COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,47QFH@768503|Cytophagia	976|Bacteroidetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
TLS3_k127_109495_6	391596.PBAL39_08405	2.443e-40	150.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,1ISXF@117747|Sphingobacteriia	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
TLS3_k127_109495_0	1237149.C900_01039	1.889e-126	409.0	COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes,47JS0@768503|Cytophagia	976|Bacteroidetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
TLS3_k127_109495_7	1237149.C900_01038	6.682e-39	146.0	COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,47R4F@768503|Cytophagia	976|Bacteroidetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
TLS3_k127_109495_4	1237149.C900_01037	2.531e-92	307.0	COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,47J8V@768503|Cytophagia	976|Bacteroidetes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
TLS3_k127_109495_2	1048983.EL17_05030	2.138e-94	313.0	COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,47KMY@768503|Cytophagia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
TLS3_k127_109495_1	1124780.ANNU01000008_gene2729	2.454e-98	331.0	COG0609@1|root,COG0609@2|Bacteria,4NEDU@976|Bacteroidetes,47KF2@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
TLS3_k127_109495_3	1237149.C900_03811	7.996e-93	314.0	COG1120@1|root,COG1120@2|Bacteria,4NG1Q@976|Bacteroidetes	976|Bacteroidetes	HP	abc transporter (atp-binding protein)	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
TLS3_k127_109495_5	485917.Phep_2105	7.652e-89	297.0	COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,1IPKK@117747|Sphingobacteriia	976|Bacteroidetes	G	COGs COG0058 Glucan phosphorylase	glgP	-	2.4.1.1,2.4.1.8	ko:K00688,ko:K00691	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R01555,R02111	RC00049	ko00000,ko00001,ko01000	-	GH65,GT35	-	DUF3417,Phosphorylase
TLS3_k127_1100216_1	1237149.C900_01990	1.684e-50	185.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, Crp Fnr family	crp	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
TLS3_k127_1100216_2	1121373.KB903625_gene3169	3.24e-30	128.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,47QDS@768503|Cytophagia	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
TLS3_k127_1100216_3	1237149.C900_03362	5.235e-26	112.0	COG3198@1|root,COG3198@2|Bacteria,4PPZ3@976|Bacteroidetes,47RV1@768503|Cytophagia	976|Bacteroidetes	S	FixH	ccoH	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
TLS3_k127_1100216_0	1237149.C900_03363	2.852e-163	522.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,47KT1@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase accessory protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
TLS3_k127_1113416_2	760192.Halhy_0726	5.044e-72	246.0	COG3386@1|root,COG3386@2|Bacteria,4NIMX@976|Bacteroidetes,1IRS9@117747|Sphingobacteriia	976|Bacteroidetes	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
TLS3_k127_1113416_3	700598.Niako_5367	7.906e-65	229.0	COG2731@1|root,COG2731@2|Bacteria,4NT2J@976|Bacteroidetes,1J157@117747|Sphingobacteriia	976|Bacteroidetes	G	COGs COG2731 Beta-galactosidase beta subunit	tabA_1	-	-	-	-	-	-	-	-	-	-	-	DUF386
TLS3_k127_1113416_0	760192.Halhy_0725	0.0	1011.0	COG1917@1|root,COG3386@1|root,COG1917@2|Bacteria,COG3386@2|Bacteria,4NF4A@976|Bacteroidetes,1IRQS@117747|Sphingobacteriia	976|Bacteroidetes	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
TLS3_k127_1113416_1	694427.Palpr_2917	5.974e-276	858.0	COG3507@1|root,COG3507@2|Bacteria,4NEMG@976|Bacteroidetes,2FPP1@200643|Bacteroidia,22WTR@171551|Porphyromonadaceae	976|Bacteroidetes	G	F5 8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_43
TLS3_k127_1113416_4	694427.Palpr_0074	1.64e-31	126.0	COG3534@1|root,COG3534@2|Bacteria,4NGMQ@976|Bacteroidetes,2FN4W@200643|Bacteroidia,22WMU@171551|Porphyromonadaceae	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C,CBM_4_9
TLS3_k127_1114599_3	313606.M23134_02568	1.162e-05	57.0	COG2203@1|root,COG3292@1|root,COG4251@1|root,COG2203@2|Bacteria,COG3292@2|Bacteria,COG4251@2|Bacteria,4NP5A@976|Bacteroidetes,47PX4@768503|Cytophagia	976|Bacteroidetes	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c
TLS3_k127_1114599_1	1237149.C900_03148	9.516e-165	530.0	COG0232@1|root,COG0232@2|Bacteria,4NENM@976|Bacteroidetes,47KD3@768503|Cytophagia	976|Bacteroidetes	F	Deoxyguanosinetriphosphate triphosphohydrolase-like protein	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
TLS3_k127_1114599_0	1237149.C900_00375	2.571e-266	827.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,47MCS@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
TLS3_k127_1114599_2	1237149.C900_00374	2.621e-61	226.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9,Reg_prop,Response_reg,STAS,Y_Y_Y
TLS3_k127_1126737_0	1237149.C900_01449	1.263e-154	492.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,47K1X@768503|Cytophagia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
TLS3_k127_1126737_2	55529.EKX50533	3.351e-30	136.0	COG4886@1|root,KOG0619@2759|Eukaryota	55529.EKX50533|-	U	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1126737_1	1121373.KB903637_gene946	2.231e-114	376.0	COG2326@1|root,COG2326@2|Bacteria,4NFJ5@976|Bacteroidetes,47JG3@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM polyphosphate nucleotide phosphotransferase, PPK2 family	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
TLS3_k127_1126737_3	1123276.KB893312_gene3079	4.832e-18	91.0	COG2771@1|root,COG2771@2|Bacteria,4NZPE@976|Bacteroidetes,47SXW@768503|Cytophagia	976|Bacteroidetes	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1146507_1	292563.Cyast_2338	5.275e-19	91.0	COG1215@1|root,COG1215@2|Bacteria,1G7KN@1117|Cyanobacteria	1117|Cyanobacteria	M	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
TLS3_k127_1146507_0	616991.JPOO01000003_gene2015	7.975e-143	458.0	COG2010@1|root,COG2010@2|Bacteria,4PMA9@976|Bacteroidetes,1HXRI@117743|Flavobacteriia,23GCK@178469|Arenibacter	976|Bacteroidetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_1146507_3	714313.LSA_07530	9.628e-08	63.0	COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli,3F3ND@33958|Lactobacillaceae	91061|Bacilli	S	Tetratricopeptide repeat protein	XK27_05225	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
TLS3_k127_114672_0	1237149.C900_03488	6.796e-283	877.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,47JAZ@768503|Cytophagia	976|Bacteroidetes	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
TLS3_k127_114672_1	1288963.ADIS_3174	1.986e-48	178.0	29WC5@1|root,30HXS@2|Bacteria,4NNWN@976|Bacteroidetes,47SJP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1155583_2	1443665.JACA01000041_gene1527	1.806e-38	147.0	COG2329@1|root,COG2329@2|Bacteria,4PHEX@976|Bacteroidetes,1II46@117743|Flavobacteriia,2YKTV@290174|Aquimarina	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1155583_1	1443665.JACA01000041_gene1526	1.651e-74	255.0	COG1309@1|root,COG1309@2|Bacteria,4NME1@976|Bacteroidetes,1I1KJ@117743|Flavobacteriia,2YK5T@290174|Aquimarina	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
TLS3_k127_1155583_0	153721.MYP_2816	2.582e-113	379.0	COG3886@1|root,COG3886@2|Bacteria,4NU12@976|Bacteroidetes,47VCE@768503|Cytophagia	976|Bacteroidetes	L	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
TLS3_k127_116116_0	1123248.KB893348_gene141	3.559e-231	719.0	COG0673@1|root,COG0673@2|Bacteria,4NJ92@976|Bacteroidetes,1ISF7@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_116116_1	925409.KI911562_gene1598	3.272e-65	224.0	COG2211@1|root,COG2211@2|Bacteria,4NE0X@976|Bacteroidetes,1J0SK@117747|Sphingobacteriia	976|Bacteroidetes	G	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
TLS3_k127_116356_0	1123248.KB893338_gene2306	1.454e-41	162.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IRGG@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_116356_3	904294.HMPREF9182_1667	2.196e-08	64.0	COG1388@1|root,COG3209@1|root,COG3210@1|root,COG1388@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1TR8F@1239|Firmicutes,4HBZE@91061|Bacilli	91061|Bacilli	M	COG3209 Rhs family protein	wapA	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0004549,GO:0006139,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016078,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575	-	-	-	-	-	-	-	-	-	-	RHS_repeat
TLS3_k127_116356_2	761193.Runsl_1980	1.163e-32	133.0	2AB14@1|root,310ER@2|Bacteria,4NNNB@976|Bacteroidetes,47Q4B@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_116356_1	388413.ALPR1_02310	2.612e-33	135.0	COG3485@1|root,COG3485@2|Bacteria,4NDXN@976|Bacteroidetes,47M90@768503|Cytophagia	976|Bacteroidetes	Q	Protocatechuate 3,4-dioxygenase beta subunit N terminal	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
TLS3_k127_1172637_1	1121904.ARBP01000013_gene339	3.697e-16	80.0	COG3203@1|root,COG3209@1|root,COG3291@1|root,COG3391@1|root,COG3203@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP_2,PKD,SprB
TLS3_k127_1172637_0	925409.KI911562_gene684	9.607e-165	527.0	COG1181@1|root,COG2940@1|root,COG1181@2|Bacteria,COG2940@2|Bacteria,4P8F6@976|Bacteroidetes	2|Bacteria	M	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Ank,Dala_Dala_lig_C,Dala_Dala_lig_N,SET
TLS3_k127_1172733_4	1237149.C900_03864	1.049e-36	142.0	COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,47PMI@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_1172733_1	1237149.C900_03863	1.571e-86	292.0	COG3279@1|root,COG3279@2|Bacteria,4NIJQ@976|Bacteroidetes,47XE0@768503|Cytophagia	976|Bacteroidetes	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_1172733_0	1237149.C900_03404	9.26e-143	471.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47MW3@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2
TLS3_k127_1172733_3	1124780.ANNU01000002_gene1609	5.138e-66	231.0	COG2094@1|root,COG2094@2|Bacteria,4NP22@976|Bacteroidetes,47JIZ@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DNA glycosylase MPG family	mpg	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
TLS3_k127_1172733_2	1237149.C900_03407	1.791e-77	268.0	COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,47PGN@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
TLS3_k127_1172733_5	929556.Solca_0470	0.0007555	45.0	2DN71@1|root,32VWQ@2|Bacteria,4NWUU@976|Bacteroidetes,1IU54@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA_like
TLS3_k127_1179597_1	1131812.JQMS01000001_gene2383	3.186e-22	96.0	2EIKE@1|root,33CBQ@2|Bacteria,4NXKH@976|Bacteroidetes,1I6R2@117743|Flavobacteriia,2NXQD@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1179597_0	1168034.FH5T_15560	7.356e-207	656.0	COG2152@1|root,COG2152@2|Bacteria,4NG76@976|Bacteroidetes,2FRCR@200643|Bacteroidia	976|Bacteroidetes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
TLS3_k127_1195042_1	1185876.BN8_00858	5.937e-56	204.0	2DBZX@1|root,2ZC4A@2|Bacteria,4NMEW@976|Bacteroidetes,47UX0@768503|Cytophagia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
TLS3_k127_1195042_0	1239962.C943_00386	1.184e-161	527.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_1202847_1	118168.MC7420_3443	3.653e-72	257.0	COG0778@1|root,COG0778@2|Bacteria,1G5XK@1117|Cyanobacteria,1HFCI@1150|Oscillatoriales	1117|Cyanobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
TLS3_k127_1202847_3	1123057.P872_21225	4.009e-65	228.0	COG3047@1|root,COG3047@2|Bacteria,4NQHT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_1202847_5	1280686.AUKE01000031_gene1554	4.397e-39	150.0	COG0454@1|root,COG0456@2|Bacteria,1VAQ8@1239|Firmicutes,24KVY@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) family	-	-	2.3.1.82	ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
TLS3_k127_1202847_2	1121904.ARBP01000002_gene6822	8.622e-68	232.0	2DK0G@1|root,30823@2|Bacteria,4NNIV@976|Bacteroidetes,47PPM@768503|Cytophagia	976|Bacteroidetes	S	Rifampin ADP-ribosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Arr-ms
TLS3_k127_1202847_0	143224.JQMD01000002_gene1525	3.67e-130	417.0	COG5297@1|root,COG5297@2|Bacteria,4NG19@976|Bacteroidetes,1I017@117743|Flavobacteriia	976|Bacteroidetes	G	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1593
TLS3_k127_1205599_2	153721.MYP_3855	2.584e-33	132.0	COG2318@1|root,COG2318@2|Bacteria,4NSRF@976|Bacteroidetes,47R2P@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_1205599_3	1107311.Q767_03865	1.209e-06	58.0	2EMGK@1|root,33F59@2|Bacteria,4NYBS@976|Bacteroidetes,1IC5X@117743|Flavobacteriia,2NWS3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1205599_0	700598.Niako_1204	1.69e-269	851.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IQ9X@117747|Sphingobacteriia	976|Bacteroidetes	V	InterPro IPR003838	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1205599_1	109760.SPPG_04804T0	5.67e-46	169.0	COG1063@1|root,KOG0024@2759|Eukaryota,38I2Z@33154|Opisthokonta,3NXYU@4751|Fungi	4751|Fungi	Q	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_12080_0	1121904.ARBP01000004_gene1059	4.123e-179	585.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_12080_1	1121904.ARBP01000004_gene1059	5.047e-93	324.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1210940_1	761193.Runsl_0870	5.029e-58	208.0	COG0657@1|root,COG0657@2|Bacteria,4NJG4@976|Bacteroidetes,47U69@768503|Cytophagia	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
TLS3_k127_1210940_2	1237149.C900_01882	1.178e-14	85.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
TLS3_k127_1210940_0	1185876.BN8_01964	3.019e-77	266.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4NHMI@976|Bacteroidetes,47K6B@768503|Cytophagia	976|Bacteroidetes	CG	Membrane-bound dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2,PmoA
TLS3_k127_1214728_3	669262.COK_0380	4.754e-38	147.0	COG0716@1|root,COG0716@2|Bacteria,1N2QA@1224|Proteobacteria,1RQ9B@1236|Gammaproteobacteria,1Y71Z@135625|Pasteurellales	135625|Pasteurellales	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1214728_1	1279009.ADICEAN_01270	2.953e-116	388.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,47JAD@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
TLS3_k127_1214728_0	1237149.C900_03745	4.811e-163	518.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,47KNQ@768503|Cytophagia	976|Bacteroidetes	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
TLS3_k127_1214728_2	1124780.ANNU01000049_gene2219	1.46e-45	168.0	2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,47PWR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1216866_0	1185876.BN8_01454	4.266e-128	417.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_1216866_4	1406840.Q763_09455	1.289e-06	52.0	COG0583@1|root,COG0583@2|Bacteria,4NGZ5@976|Bacteroidetes,1HXGU@117743|Flavobacteriia,2NSYW@237|Flavobacterium	976|Bacteroidetes	K	LysR family transcriptional regulator	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
TLS3_k127_1216866_1	700598.Niako_7284	6.54e-61	220.0	COG4977@1|root,COG4977@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
TLS3_k127_1216866_2	700598.Niako_7285	1.568e-38	148.0	COG2318@1|root,COG2318@2|Bacteria,4NRSP@976|Bacteroidetes,1IYQJ@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
TLS3_k127_1216866_5	1411123.JQNH01000001_gene3319	0.0001126	50.0	COG5470@1|root,COG5470@2|Bacteria,1N7JA@1224|Proteobacteria,2UBQW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	MA20_24570	-	-	-	-	-	-	-	-	-	-	-	DUF1330
TLS3_k127_1216866_3	1408813.AYMG01000008_gene3934	8.808e-35	141.0	2E047@1|root,2ZJQK@2|Bacteria,4P6XA@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1221845_2	700598.Niako_1804	5.108e-61	221.0	COG4585@1|root,COG4585@2|Bacteria,4NG0M@976|Bacteroidetes,1IXEX@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	narQ	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,PilJ
TLS3_k127_1221845_1	1237149.C900_01498	5.567e-74	268.0	COG4251@1|root,COG5000@1|root,COG4251@2|Bacteria,COG5000@2|Bacteria,4NDUQ@976|Bacteroidetes,47PTN@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
TLS3_k127_1221845_0	746697.Aeqsu_2143	2.341e-128	441.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,1HWUK@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_1228702_3	1121897.AUGO01000013_gene3301	2.527e-14	73.0	2C5VR@1|root,32CJG@2|Bacteria,4NQV8@976|Bacteroidetes,1I302@117743|Flavobacteriia,2NW91@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1228702_1	1197906.CAJQ02000009_gene3622	7.019e-47	173.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,2U922@28211|Alphaproteobacteria,3JY6M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS3_k127_1228702_2	471854.Dfer_2857	1.087e-34	138.0	29AKN@1|root,2ZXKK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1228702_0	1185876.BN8_02312	1.608e-153	500.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,47JKN@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,YdjC
TLS3_k127_1228969_0	1550091.JROE01000002_gene819	0.0	1400.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
TLS3_k127_1228969_1	1122605.KB893626_gene2419	1.792e-06	50.0	COG0614@1|root,COG0614@2|Bacteria,4NEF0@976|Bacteroidetes,1IW0U@117747|Sphingobacteriia	976|Bacteroidetes	P	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_1230069_1	1123277.KB893216_gene4863	2.882e-27	121.0	COG3279@1|root,COG3279@2|Bacteria,4NNHE@976|Bacteroidetes,47XDX@768503|Cytophagia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_1230069_0	1123277.KB893216_gene4864	5.459e-97	348.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,47V2C@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
TLS3_k127_12396_0	760192.Halhy_5751	1.038e-156	502.0	2CK59@1|root,335GM@2|Bacteria,4NYUR@976|Bacteroidetes,1IWCN@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1253223_1	1237149.C900_03265	4.883e-244	759.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,47K18@768503|Cytophagia	976|Bacteroidetes	C	PFAM Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
TLS3_k127_1253223_0	1237149.C900_03264	0.0	1268.0	COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,47NK7@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S dicluster domain	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
TLS3_k127_1253223_2	1237149.C900_03263	5.248e-157	503.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,47J8Z@768503|Cytophagia	976|Bacteroidetes	C	PFAM Class III cytochrome C family	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
TLS3_k127_1261686_0	485917.Phep_2234	4.883e-100	336.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,1IQ2G@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_1261686_2	1237149.C900_02573	3.765e-48	177.0	COG4430@1|root,COG4430@2|Bacteria,4NQAJ@976|Bacteroidetes,47QIH@768503|Cytophagia	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
TLS3_k127_1261686_3	1237149.C900_05649	2.823e-41	162.0	COG2207@1|root,COG2207@2|Bacteria,4NHA5@976|Bacteroidetes,47U27@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_1261686_4	1379698.RBG1_1C00001G0617	4.207e-33	133.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_1261686_1	153721.MYP_3617	4.288e-49	180.0	COG4430@1|root,COG4430@2|Bacteria,4NR0U@976|Bacteroidetes,47PZ9@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
TLS3_k127_1265363_1	398720.MED217_11609	0.0009923	43.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia,2XI0Q@283735|Leeuwenhoekiella	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
TLS3_k127_1265363_0	760192.Halhy_1519	0.0	1219.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IVZC@117747|Sphingobacteriia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
TLS3_k127_1287831_0	700598.Niako_5257	5.442e-240	753.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1IRKR@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Bacterial protein of	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
TLS3_k127_1287831_3	929556.Solca_0457	3.232e-37	145.0	2E4RV@1|root,32ZKD@2|Bacteria,4NWUE@976|Bacteroidetes,1IU9D@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1287831_1	1121895.Q765_03795	4.621e-178	566.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1I0J0@117743|Flavobacteriia,2NU5T@237|Flavobacterium	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	dctA	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
TLS3_k127_1287831_2	761193.Runsl_2599	4.561e-139	470.0	COG1352@1|root,COG2201@1|root,COG3883@1|root,COG4251@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG3883@2|Bacteria,COG4251@2|Bacteria,4NE3J@976|Bacteroidetes,47XZS@768503|Cytophagia	976|Bacteroidetes	T	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_9
TLS3_k127_1298709_1	929713.NIASO_06990	9.015e-116	382.0	2DBNR@1|root,2ZA54@2|Bacteria,4NHW9@976|Bacteroidetes,1IRGS@117747|Sphingobacteriia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
TLS3_k127_1298709_0	509635.N824_23560	2.846e-220	690.0	COG0673@1|root,COG0673@2|Bacteria,4NHDS@976|Bacteroidetes,1IVBU@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_1312841_0	1121481.AUAS01000007_gene1085	6.299e-265	839.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,47JGS@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
TLS3_k127_1312841_2	643867.Ftrac_0563	1.754e-21	98.0	2DS6V@1|root,33ETJ@2|Bacteria,4NY48@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1312841_1	643867.Ftrac_0564	3.512e-42	161.0	COG4083@1|root,COG4083@2|Bacteria,4NM52@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Transmembrane exosortase (Exosortase_EpsH)	groEL	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
TLS3_k127_1312841_3	742740.HMPREF9474_03246	1.369e-05	49.0	COG1044@1|root,COG1044@2|Bacteria,1TP7W@1239|Firmicutes,24HJW@186801|Clostridia	186801|Clostridia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
TLS3_k127_133285_0	1237149.C900_04780	7.828e-233	728.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,47K1E@768503|Cytophagia	976|Bacteroidetes	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
TLS3_k127_133285_6	1237149.C900_04776	4.777e-37	144.0	COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes,47R5X@768503|Cytophagia	976|Bacteroidetes	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_133285_5	1443665.JACA01000059_gene1120	1.525e-38	151.0	COG1053@1|root,COG1053@2|Bacteria,4PPUY@976|Bacteroidetes,1IKUK@117743|Flavobacteriia,2YM79@290174|Aquimarina	976|Bacteroidetes	C	succinate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_133285_3	1237149.C900_04657	2.925e-159	515.0	COG0733@1|root,COG0733@2|Bacteria,4NGQ5@976|Bacteroidetes,47NFV@768503|Cytophagia	976|Bacteroidetes	U	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
TLS3_k127_133285_1	1237149.C900_04771	2.459e-216	680.0	COG1057@1|root,COG1057@2|Bacteria,4NEIR@976|Bacteroidetes,47KX5@768503|Cytophagia	976|Bacteroidetes	H	Nicotinate-nucleotide adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_133285_2	1237149.C900_01566	6.263e-163	525.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,47JCJ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Sodium alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
TLS3_k127_133285_4	1237149.C900_01568	1.524e-142	460.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,47KSG@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS3_k127_1334412_4	1279009.ADICEAN_01464	5.045e-75	253.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,47PVC@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM 6-pyruvoyl tetrahydropterin synthase QueD family protein	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
TLS3_k127_1334412_1	1237149.C900_00199	2.192e-127	418.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,47JDC@768503|Cytophagia	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
TLS3_k127_1334412_0	1237149.C900_00196	3.984e-223	696.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,47JDR@768503|Cytophagia	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
TLS3_k127_1334412_2	1237149.C900_00195	8.739e-110	358.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,47K60@768503|Cytophagia	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
TLS3_k127_1334412_3	1237149.C900_00194	2.228e-95	322.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,47KTD@768503|Cytophagia	976|Bacteroidetes	O	Trigger factor	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
TLS3_k127_1336465_1	641524.ADICYQ_0798	1.05e-05	55.0	2DQSW@1|root,338FU@2|Bacteria,4NYF2@976|Bacteroidetes,47S19@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
TLS3_k127_1336465_0	880070.Cycma_3561	1.72e-289	908.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47MDX@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_1338680_1	1216967.L100_09159	8.607e-43	161.0	COG0262@1|root,COG0262@2|Bacteria,4NPJF@976|Bacteroidetes,1I4ZF@117743|Flavobacteriia,34RCM@308865|Elizabethkingia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
TLS3_k127_1338680_2	1150600.ADIARSV_3660	4.239e-37	142.0	2D2Z4@1|root,32TDX@2|Bacteria,4NVF7@976|Bacteroidetes,1IYZR@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3024)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3024
TLS3_k127_1338680_0	388413.ALPR1_17088	4.05e-45	176.0	COG3712@1|root,COG3712@2|Bacteria,4NREY@976|Bacteroidetes,47Q61@768503|Cytophagia	976|Bacteroidetes	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
TLS3_k127_1338867_2	1237149.C900_00541	8.982e-49	181.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,47PIA@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_1338867_3	1286632.P278_20860	5.48e-34	136.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I23H@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
TLS3_k127_1338867_1	1237149.C900_00541	4.509e-58	212.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,47PIA@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_1338867_0	1237149.C900_03383	2.218e-224	720.0	COG2217@1|root,COG2217@2|Bacteria,4NEI1@976|Bacteroidetes,47N4X@768503|Cytophagia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
TLS3_k127_1338867_4	319236.JCM19294_2030	9.105e-12	68.0	COG3197@1|root,COG3197@2|Bacteria,4NUR7@976|Bacteroidetes,1I562@117743|Flavobacteriia,3HKT9@363408|Nonlabens	976|Bacteroidetes	P	Cytochrome oxidase maturation protein cbb3-type	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
TLS3_k127_1338867_5	1380384.JADN01000006_gene2512	1.08e-11	65.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,1HYDQ@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
TLS3_k127_1339374_7	1166018.FAES_4787	2.958e-22	98.0	COG2928@1|root,COG2928@2|Bacteria,4NR4F@976|Bacteroidetes,47QB1@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
TLS3_k127_1339374_5	1185876.BN8_01076	8.247e-32	131.0	COG3637@1|root,COG3637@2|Bacteria,4NV08@976|Bacteroidetes,47R7Z@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_1339374_0	1237149.C900_02247	6.828e-188	593.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,47KX3@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
TLS3_k127_1339374_1	643867.Ftrac_2945	1.18e-136	447.0	COG0526@1|root,COG0526@2|Bacteria,4PMB3@976|Bacteroidetes,47JVX@768503|Cytophagia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
TLS3_k127_1339374_2	1237149.C900_02241	1.921e-135	441.0	COG1804@1|root,COG1804@2|Bacteria,4NEA8@976|Bacteroidetes,47NJE@768503|Cytophagia	976|Bacteroidetes	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
TLS3_k127_1339374_3	1237149.C900_02239	9.192e-66	228.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,47Q53@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
TLS3_k127_1339374_6	313598.MED152_04195	1.16e-23	103.0	2DNS7@1|root,32YWC@2|Bacteria,4NSJ6@976|Bacteroidetes,1IJQA@117743|Flavobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
TLS3_k127_1339374_4	929562.Emtol_1669	1.476e-38	146.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,47JJ6@768503|Cytophagia	976|Bacteroidetes	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
TLS3_k127_1355789_0	402612.FP1358	4.4e-149	482.0	COG1253@1|root,COG1253@2|Bacteria,4NE9R@976|Bacteroidetes,1HZZZ@117743|Flavobacteriia,2NT22@237|Flavobacterium	976|Bacteroidetes	S	Transporter associated domain	corC_1	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
TLS3_k127_1355789_2	313596.RB2501_12047	6.694e-09	62.0	2BZ54@1|root,3342Z@2|Bacteria,4NVGG@976|Bacteroidetes,1I59B@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1355789_1	926549.KI421517_gene2934	2.397e-102	341.0	COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,47K2C@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
TLS3_k127_1367917_0	1150621.SMUL_1797	8.054e-119	389.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
TLS3_k127_1367917_1	1122991.BAIZ01000025_gene1905	3.136e-77	267.0	COG3617@1|root,COG3617@2|Bacteria,4NTS1@976|Bacteroidetes	976|Bacteroidetes	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ANT,Bro-N
TLS3_k127_1370300_3	471854.Dfer_0118	2.922e-14	79.0	29XQK@1|root,30JGA@2|Bacteria,4NNS6@976|Bacteroidetes,47SDP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1370300_2	1249997.JHZW01000002_gene1143	8.63e-54	198.0	COG0398@1|root,COG0398@2|Bacteria,4NFIC@976|Bacteroidetes,1HXVB@117743|Flavobacteriia,2PID0@252356|Maribacter	976|Bacteroidetes	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
TLS3_k127_1370300_0	926560.KE387027_gene751	1.75e-216	689.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_13834_1	504472.Slin_1760	1.374e-92	315.0	COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_13834_0	1123277.KB893174_gene5903	6.421e-224	707.0	COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_1384108_0	1408813.AYMG01000031_gene1501	1.51e-193	623.0	COG3534@1|root,COG3534@2|Bacteria,4NJ6F@976|Bacteroidetes,1IR42@117747|Sphingobacteriia	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1384108_1	1121481.AUAS01000007_gene1170	9.237e-82	281.0	28K2Q@1|root,2Z9S1@2|Bacteria,4NH0K@976|Bacteroidetes,47MG8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TIG
TLS3_k127_138999_2	1121904.ARBP01000018_gene2704	4.973e-85	286.0	COG4409@1|root,COG4409@2|Bacteria,4NIJX@976|Bacteroidetes,47MH2@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TLS3_k127_138999_3	1123277.KB893244_gene5154	7.801e-52	196.0	COG0584@1|root,COG0584@2|Bacteria,4NW6B@976|Bacteroidetes,47XAH@768503|Cytophagia	976|Bacteroidetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
TLS3_k127_138999_0	504472.Slin_6614	3.43e-204	644.0	COG4287@1|root,COG4287@2|Bacteria,4NI0U@976|Bacteroidetes,47KB9@768503|Cytophagia	976|Bacteroidetes	S	PhoPQ-activated pathogenicity-related protein	-	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
TLS3_k127_138999_1	471854.Dfer_3218	4.728e-193	610.0	COG3356@1|root,COG3356@2|Bacteria,4NHGJ@976|Bacteroidetes,47N67@768503|Cytophagia	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_138999_5	7176.CPIJ016596-PA	2.443e-06	50.0	2CY4I@1|root,2S1ZX@2759|Eukaryota,3A4ME@33154|Opisthokonta,3BS4H@33208|Metazoa,3D949@33213|Bilateria,42AYK@6656|Arthropoda,3T0CF@50557|Insecta	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_138999_4	1121904.ARBP01000018_gene2701	1.236e-47	172.0	COG1409@1|root,COG1409@2|Bacteria,4NEYU@976|Bacteroidetes,47KM8@768503|Cytophagia	976|Bacteroidetes	S	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
TLS3_k127_13900_4	1121887.AUDK01000003_gene2716	1.185e-06	54.0	2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes,1HZN8@117743|Flavobacteriia,2NVIV@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
TLS3_k127_13900_2	471854.Dfer_4644	3.159e-43	164.0	COG1670@1|root,COG1670@2|Bacteria,4NNBE@976|Bacteroidetes,47QK7@768503|Cytophagia	976|Bacteroidetes	J	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_13900_0	388413.ALPR1_02900	2.085e-260	839.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4NPTY@976|Bacteroidetes,47UE4@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TLS3_k127_13900_1	1121904.ARBP01000010_gene2461	9.36e-150	483.0	COG2133@1|root,COG2133@2|Bacteria,4NF61@976|Bacteroidetes,47KFM@768503|Cytophagia	976|Bacteroidetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS3_k127_13900_3	1239962.C943_02390	5.17e-22	96.0	COG3556@1|root,COG3556@2|Bacteria,4NSFQ@976|Bacteroidetes	976|Bacteroidetes	S	Predicted membrane protein (DUF2214)	-	-	-	ko:K08983	-	-	-	-	ko00000	-	-	-	DUF2214
TLS3_k127_1392576_1	1121904.ARBP01000013_gene371	1.413e-135	453.0	2CB42@1|root,2Z7Y3@2|Bacteria,4NEUY@976|Bacteroidetes,47N6R@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1392576_2	1267211.KI669560_gene1015	4.306e-19	91.0	2EAT9@1|root,334V5@2|Bacteria,4NUP8@976|Bacteroidetes,1IZND@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1392576_0	1408813.AYMG01000008_gene3914	0.0	1557.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IQBJ@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
TLS3_k127_1406641_2	1237149.C900_02644	1.414e-61	216.0	2CC1H@1|root,33P9C@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
TLS3_k127_1406641_1	1237149.C900_02642	9.689e-68	233.0	COG1595@1|root,COG1595@2|Bacteria,4NSED@976|Bacteroidetes,47Q3K@768503|Cytophagia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_1406641_0	1123277.KB893173_gene1827	2.192e-159	530.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,47JM8@768503|Cytophagia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3829,VWA,VWA_2
TLS3_k127_1406721_0	1124780.ANNU01000005_gene2458	1.201e-206	646.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,47JEH@768503|Cytophagia	976|Bacteroidetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
TLS3_k127_1406721_2	1237149.C900_02810	2.161e-181	571.0	COG0208@1|root,COG0208@2|Bacteria,4NG18@976|Bacteroidetes,47MSG@768503|Cytophagia	976|Bacteroidetes	F	reductase, small chain	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
TLS3_k127_1406721_3	1239962.C943_02687	1.108e-43	162.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,47R7R@768503|Cytophagia	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
TLS3_k127_1406721_4	865938.Weevi_1116	2.23e-37	141.0	COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,1I2S0@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
TLS3_k127_1406721_1	929562.Emtol_3061	1.943e-204	649.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47K6G@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_1408097_1	1123277.KB893228_gene2070	3.197e-48	179.0	COG0613@1|root,COG0613@2|Bacteria,4PMKK@976|Bacteroidetes,47NYR@768503|Cytophagia	976|Bacteroidetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1408097_0	1237149.C900_03692	2e-322	994.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,47JRN@768503|Cytophagia	976|Bacteroidetes	F	PFAM Glutamine amidotransferase, class-II	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7
TLS3_k127_1423518_2	1237149.C900_02195	4.108e-100	329.0	COG0318@1|root,COG0318@2|Bacteria,4PKQG@976|Bacteroidetes,47K42@768503|Cytophagia	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
TLS3_k127_1423518_4	1237149.C900_02194	2.921e-42	163.0	COG1280@1|root,COG1280@2|Bacteria,4NH3F@976|Bacteroidetes,47NRD@768503|Cytophagia	976|Bacteroidetes	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
TLS3_k127_1423518_0	1237149.C900_02193	2.407e-156	499.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,47JUP@768503|Cytophagia	976|Bacteroidetes	S	PFAM von Willebrand factor type A	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
TLS3_k127_1423518_3	1237149.C900_02192	9.409e-68	241.0	2BPYJ@1|root,32ISF@2|Bacteria,4NRVJ@976|Bacteroidetes,47QN3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1423518_1	1237149.C900_02191	4.835e-137	441.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,47JXB@768503|Cytophagia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TLS3_k127_1427851_1	1237149.C900_01307	1.092e-80	277.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47UC8@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_1427851_0	1121904.ARBP01000008_gene3264	9.268e-319	982.0	COG2382@1|root,COG3386@1|root,COG2382@2|Bacteria,COG3386@2|Bacteria,4NK15@976|Bacteroidetes,47MMH@768503|Cytophagia	976|Bacteroidetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,SGL
TLS3_k127_1428269_2	714943.Mucpa_4707	3.903e-47	174.0	COG1801@1|root,COG1801@2|Bacteria,4NHAD@976|Bacteroidetes,1IP8N@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
TLS3_k127_1428269_0	761193.Runsl_3929	1.15e-285	884.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,47JC1@768503|Cytophagia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_1428269_1	1237149.C900_03338	7.879e-80	271.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,47TX8@768503|Cytophagia	976|Bacteroidetes	H	Lumazine binding domain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
TLS3_k127_1438464_1	1237149.C900_04402	3.54e-104	341.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,47JE5@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
TLS3_k127_1438464_0	1123057.P872_19260	8.823e-135	432.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,47KHR@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
TLS3_k127_1438464_2	1237149.C900_02495	1.426e-36	144.0	COG2032@1|root,COG2032@2|Bacteria,4NX0Y@976|Bacteroidetes,47SBX@768503|Cytophagia	976|Bacteroidetes	P	superoxide dismutase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1440100_0	1239962.C943_00386	1.796e-170	554.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_1440100_1	929703.KE386491_gene1730	1.386e-68	235.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47MYR@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_144966_2	247490.KSU1_D1003	4.03e-27	112.0	COG0845@1|root,COG0845@2|Bacteria,2IYKR@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS3_k127_144966_0	247490.KSU1_D1002	0.0	1670.0	COG0841@1|root,COG0841@2|Bacteria,2IX2G@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
TLS3_k127_144966_1	247490.KSU1_D1001	2.686e-179	573.0	COG1538@1|root,COG1538@2|Bacteria,2IX0B@203682|Planctomycetes	203682|Planctomycetes	MU	outer membrane lipoprotein IbeB	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_1449956_0	1453498.LG45_09075	3.529e-86	297.0	COG0642@1|root,COG2199@1|root,COG2199@2|Bacteria,COG2205@2|Bacteria,4P15P@976|Bacteroidetes,1IK2K@117743|Flavobacteriia,2P0U3@237|Flavobacterium	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_1449956_1	1089547.KB913014_gene4825	4.946e-29	120.0	COG2259@1|root,COG2259@2|Bacteria,4PMH5@976|Bacteroidetes	976|Bacteroidetes	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
TLS3_k127_1457161_4	1453498.LG45_14445	2.034e-12	71.0	COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,1I20T@117743|Flavobacteriia,2P071@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
TLS3_k127_1457161_1	1237149.C900_00936	8.354e-110	361.0	COG4783@1|root,COG4783@2|Bacteria,4PKN7@976|Bacteroidetes,47YC0@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TLS3_k127_1457161_3	1122179.KB890418_gene3749	3.259e-64	226.0	COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,1INU6@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM fumarylacetoacetate (FAA) hydrolase	fahA	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
TLS3_k127_1457161_0	1279009.ADICEAN_01651	1.117e-148	493.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,47JZB@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_1457161_2	1237149.C900_05652	6.288e-71	244.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,47PUA@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
TLS3_k127_1472391_0	1121904.ARBP01000015_gene179	2.327e-242	769.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1472391_1	880070.Cycma_2723	1.326e-162	519.0	28JXN@1|root,2Z9N3@2|Bacteria,4NJUA@976|Bacteroidetes,47NJF@768503|Cytophagia	976|Bacteroidetes	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
TLS3_k127_1472391_3	1288963.ADIS_3681	6.069e-62	220.0	COG0745@1|root,COG0745@2|Bacteria,4NE77@976|Bacteroidetes,47K3Z@768503|Cytophagia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_1472391_2	504472.Slin_4055	2.369e-77	276.0	COG4251@1|root,COG4251@2|Bacteria,4PN2Y@976|Bacteroidetes,47Y7N@768503|Cytophagia	976|Bacteroidetes	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_1481159_0	1121904.ARBP01000004_gene976	3.111e-234	750.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,4NEC4@976|Bacteroidetes,47M1P@768503|Cytophagia	976|Bacteroidetes	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
TLS3_k127_1481159_2	395493.BegalDRAFT_2645	4.457e-88	299.0	COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,1RNV8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
TLS3_k127_1481159_1	1237149.C900_03808	1.912e-142	461.0	COG0614@1|root,COG0614@2|Bacteria,4NH9F@976|Bacteroidetes,47MZX@768503|Cytophagia	976|Bacteroidetes	P	PFAM periplasmic binding protein	btuF	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
TLS3_k127_1501854_1	1048983.EL17_05965	1.042e-129	428.0	COG1506@1|root,COG2304@1|root,COG1506@2|Bacteria,COG2304@2|Bacteria,4NKZ6@976|Bacteroidetes,47P9T@768503|Cytophagia	976|Bacteroidetes	E	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_1501854_0	760192.Halhy_3517	4.949e-171	547.0	COG0793@1|root,COG0793@2|Bacteria,4NGGJ@976|Bacteroidetes,1ITFP@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
TLS3_k127_1503991_3	1121481.AUAS01000001_gene4420	2.27e-25	106.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,47RX4@768503|Cytophagia	976|Bacteroidetes	K	Cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
TLS3_k127_1503991_4	1196031.ALEG01000047_gene204	5.392e-23	99.0	COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli,1ZIX5@1386|Bacillus	91061|Bacilli	S	Uncharacterized conserved protein (DUF2196)	ywbE	-	-	-	-	-	-	-	-	-	-	-	DUF2196
TLS3_k127_1503991_1	929703.KE386491_gene3305	1.534e-103	350.0	COG1524@1|root,COG1524@2|Bacteria,4NFFG@976|Bacteroidetes,47MMJ@768503|Cytophagia	976|Bacteroidetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phosphodiest
TLS3_k127_1503991_0	929556.Solca_3818	7.726e-296	919.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HTH_18,TPR_16,TPR_2,TPR_8
TLS3_k127_1503991_2	109760.SPPG_04804T0	1.399e-63	223.0	COG1063@1|root,KOG0024@2759|Eukaryota,38I2Z@33154|Opisthokonta,3NXYU@4751|Fungi	4751|Fungi	Q	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_1517029_2	1237149.C900_04087	5.298e-77	263.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes	976|Bacteroidetes	V	permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1517029_0	1237149.C900_04087	5.176e-258	818.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes	976|Bacteroidetes	V	permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1517029_1	1237149.C900_04088	6.896e-148	485.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JYF@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_1518475_3	1220582.RRU01S_13_00160	8.689e-47	185.0	COG1120@1|root,COG1120@2|Bacteria	2|Bacteria	HP	ATPase activity	-	-	3.6.3.34	ko:K02013,ko:K02071,ko:K03546	ko02010,map02010	M00238,M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko03400	3.A.1.14,3.A.1.24	-	-	AAA_15,AAA_21,ABC_tran
TLS3_k127_1518475_2	1123057.P872_06580	1.661e-57	207.0	COG2141@1|root,COG2141@2|Bacteria,4NPX8@976|Bacteroidetes,47QFN@768503|Cytophagia	976|Bacteroidetes	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1518475_0	755732.Fluta_3673	2.621e-117	387.0	COG5263@1|root,COG5263@2|Bacteria,4NJ6B@976|Bacteroidetes,1HX7Q@117743|Flavobacteriia,2PBII@246874|Cryomorphaceae	976|Bacteroidetes	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
TLS3_k127_1518475_5	391587.KAOT1_19397	2.842e-22	108.0	COG0726@1|root,COG0726@2|Bacteria,4NN39@976|Bacteroidetes,1I52I@117743|Flavobacteriia	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
TLS3_k127_1518475_4	1408445.JHXP01000006_gene126	4.095e-29	129.0	COG1247@1|root,COG1247@2|Bacteria,1PZ4K@1224|Proteobacteria,1T7VF@1236|Gammaproteobacteria,1JFWU@118969|Legionellales	118969|Legionellales	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
TLS3_k127_1518475_1	1237149.C900_05012	7.768e-117	381.0	COG0024@1|root,COG0024@2|Bacteria,4NEAT@976|Bacteroidetes,47KJV@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM methionine aminopeptidase, type I	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
TLS3_k127_1518475_6	1348583.ATLH01000003_gene3882	7.782e-16	83.0	COG2304@1|root,COG2304@2|Bacteria,4NKZ6@976|Bacteroidetes,1I1QN@117743|Flavobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_1519515_0	1150600.ADIARSV_3322	5.048e-109	382.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IQ0T@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1519515_1	1123277.KB893203_gene6259	3.163e-61	214.0	COG0624@1|root,COG0624@2|Bacteria,4NJEK@976|Bacteroidetes,47N41@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M20/M25/M40	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
TLS3_k127_1521308_3	1150600.ADIARSV_1526	2.762e-16	79.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1IP2X@117747|Sphingobacteriia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_1521308_2	1122197.ATWI01000002_gene2403	2.524e-26	117.0	2A07X@1|root,30NB4@2|Bacteria,1N1WT@1224|Proteobacteria,1S9GH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
TLS3_k127_1521308_1	1237149.C900_05490	1.284e-77	264.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,47P8Y@768503|Cytophagia	976|Bacteroidetes	S	PFAM Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
TLS3_k127_1521308_0	1237149.C900_05489	6.427e-123	397.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,47KDU@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_1528930_2	1121957.ATVL01000011_gene3912	1.238e-36	145.0	COG2318@1|root,COG2318@2|Bacteria,4NP2C@976|Bacteroidetes,47Q0U@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_1528930_0	1237149.C900_04486	1.183e-159	512.0	COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,47KRS@768503|Cytophagia	976|Bacteroidetes	E	Alanine dehydrogenase PNT, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
TLS3_k127_1528930_1	1230342.CTM_15058	3.349e-84	285.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,36ICC@31979|Clostridiaceae	186801|Clostridia	S	hemolysin III	hlyIII	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
TLS3_k127_1529692_2	1237149.C900_02638	1.505e-141	465.0	COG1538@1|root,COG1538@2|Bacteria,4NEH3@976|Bacteroidetes,47JKK@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_1529692_1	1237149.C900_02637	4.036e-155	501.0	COG0845@1|root,COG0845@2|Bacteria,4NFEK@976|Bacteroidetes,47JV7@768503|Cytophagia	976|Bacteroidetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
TLS3_k127_1529692_0	1237149.C900_02636	1.052e-236	752.0	COG2274@1|root,COG2274@2|Bacteria,4NFJF@976|Bacteroidetes,47K3G@768503|Cytophagia	976|Bacteroidetes	V	PFAM ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
TLS3_k127_1529692_3	1121904.ARBP01000040_gene520	7.763e-62	220.0	COG1309@1|root,COG1309@2|Bacteria,4NEUA@976|Bacteroidetes,47P97@768503|Cytophagia	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_153051_2	1121904.ARBP01000002_gene6868	2.034e-45	181.0	COG2312@1|root,COG2312@2|Bacteria,4NF9R@976|Bacteroidetes,47KA6@768503|Cytophagia	976|Bacteroidetes	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
TLS3_k127_153051_0	761193.Runsl_4932	0.0	1239.0	COG4946@1|root,COG4946@2|Bacteria,4NJFC@976|Bacteroidetes,47JWA@768503|Cytophagia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_153051_1	761193.Runsl_0432	5.179e-184	583.0	COG4948@1|root,COG4948@2|Bacteria,4NKNN@976|Bacteroidetes,47JKW@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
TLS3_k127_1531699_0	643867.Ftrac_0991	2.527e-317	987.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47Y5N@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_1531699_1	1237149.C900_04960	2.801e-219	696.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47MTM@768503|Cytophagia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
TLS3_k127_1536666_3	1121895.Q765_20270	5.076e-36	139.0	COG3503@1|root,COG3503@2|Bacteria,4NFAF@976|Bacteroidetes,1HX24@117743|Flavobacteriia,2NTT8@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
TLS3_k127_1536666_0	468059.AUHA01000002_gene278	8.075e-115	381.0	COG2706@1|root,COG2706@2|Bacteria,4NE87@976|Bacteroidetes,1INQI@117747|Sphingobacteriia	976|Bacteroidetes	G	3-carboxymuconate cyclase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
TLS3_k127_1536666_1	1123248.KB893321_gene475	7.872e-71	247.0	COG2159@1|root,COG2159@2|Bacteria,4NH6P@976|Bacteroidetes	976|Bacteroidetes	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1536666_2	1239962.C943_01704	5.815e-41	162.0	28KF4@1|root,2ZA1C@2|Bacteria,4NNRR@976|Bacteroidetes,47UXU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BetR
TLS3_k127_1538520_1	1121859.KB890760_gene2098	8.465e-86	285.0	COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,47P99@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
TLS3_k127_1538520_0	1237149.C900_00193	0.0	1097.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,47JQ8@768503|Cytophagia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
TLS3_k127_1538520_3	1300143.CCAV010000001_gene955	2.329e-07	56.0	29EH7@1|root,301F5@2|Bacteria,4PGMM@976|Bacteroidetes,1IHES@117743|Flavobacteriia,3ZU3J@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1538520_2	643867.Ftrac_1137	3.161e-51	184.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,47KTD@768503|Cytophagia	976|Bacteroidetes	O	Trigger factor	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
TLS3_k127_1541087_3	643867.Ftrac_3711	4.431e-23	99.0	COG4864@1|root,COG4864@2|Bacteria,4NGG6@976|Bacteroidetes,47KKM@768503|Cytophagia	976|Bacteroidetes	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
TLS3_k127_1541087_2	1237149.C900_02886	8.447e-162	534.0	COG0515@1|root,COG0515@2|Bacteria	1237149.C900_02886|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1541087_1	1237149.C900_02885	8.758e-207	651.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,4NE2Y@976|Bacteroidetes,47KD4@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
TLS3_k127_1541087_0	1121481.AUAS01000013_gene4140	6.452e-282	883.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,4NIPS@976|Bacteroidetes,47M8S@768503|Cytophagia	976|Bacteroidetes	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
TLS3_k127_154757_2	1237149.C900_04102	5.911e-84	286.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,47KQP@768503|Cytophagia	976|Bacteroidetes	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
TLS3_k127_154757_1	313606.M23134_00725	1.588e-104	347.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,47JQY@768503|Cytophagia	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
TLS3_k127_154757_5	1237149.C900_04104	7.202e-34	135.0	2E6VI@1|root,331F4@2|Bacteria,4NWUI@976|Bacteroidetes,47T84@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_154757_0	1237149.C900_04785	3.469e-173	550.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JKI@768503|Cytophagia	976|Bacteroidetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_154757_4	1237149.C900_03992	7.907e-37	147.0	COG0671@1|root,COG0671@2|Bacteria,4NUPJ@976|Bacteroidetes,47PT7@768503|Cytophagia	976|Bacteroidetes	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_154757_3	926549.KI421517_gene800	1.025e-68	235.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,47KC2@768503|Cytophagia	976|Bacteroidetes	K	RNA polymerase, sigma-54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
TLS3_k127_1550571_3	1519464.HY22_07390	9.209e-31	121.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	ble	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
TLS3_k127_1550571_1	1089547.KB913013_gene881	9.971e-96	316.0	2CA4G@1|root,2Z7UW@2|Bacteria,4NFG9@976|Bacteroidetes,47KPW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1550571_2	649349.Lbys_0957	8.475e-68	235.0	arCOG06733@1|root,313GU@2|Bacteria,4NQIM@976|Bacteroidetes,47QTF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1550571_0	929556.Solca_3818	1.124e-150	498.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HTH_18,TPR_16,TPR_2,TPR_8
TLS3_k127_1551799_2	1356852.N008_20230	8.689e-17	80.0	COG3620@1|root,COG3620@2|Bacteria,4NV6Z@976|Bacteroidetes,47RVV@768503|Cytophagia	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
TLS3_k127_1551799_1	761193.Runsl_4266	9.068e-50	179.0	COG3550@1|root,COG3550@2|Bacteria,4NTCR@976|Bacteroidetes,47S3B@768503|Cytophagia	976|Bacteroidetes	S	HipA N-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA
TLS3_k127_1551799_0	761193.Runsl_4265	1.862e-152	486.0	COG3550@1|root,COG3550@2|Bacteria,4NG6N@976|Bacteroidetes,47MIR@768503|Cytophagia	976|Bacteroidetes	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	HipA_C
TLS3_k127_1555276_2	1279009.ADICEAN_03351	6.123e-83	297.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4P1E3@976|Bacteroidetes,47TRZ@768503|Cytophagia	976|Bacteroidetes	U	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1555276_3	643867.Ftrac_1238	2.343e-75	264.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,47KE6@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_1555276_0	1249975.JQLP01000005_gene2506	9.752e-129	438.0	COG1357@1|root,COG1361@1|root,COG1520@1|root,COG2304@1|root,COG2911@1|root,COG1357@2|Bacteria,COG1361@2|Bacteria,COG1520@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,4NMB8@976|Bacteroidetes,1IJKA@117743|Flavobacteriia	976|Bacteroidetes	M	Pfam C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,HYR,SdrD_B
TLS3_k127_1555276_1	153721.MYP_3597	1.588e-104	347.0	COG0697@1|root,COG0697@2|Bacteria,4NM5K@976|Bacteroidetes,47TMU@768503|Cytophagia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_1555276_4	269798.CHU_1923	1.789e-17	93.0	2C89Z@1|root,330RF@2|Bacteria,4NVA2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1563041_3	1237149.C900_04428	9.144e-48	173.0	COG1695@1|root,COG1695@2|Bacteria,4P48E@976|Bacteroidetes,47V9J@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_1563041_2	1173020.Cha6605_5378	3.33e-54	192.0	COG0614@1|root,COG0614@2|Bacteria,1G79B@1117|Cyanobacteria	1117|Cyanobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
TLS3_k127_1563041_1	471854.Dfer_0140	5.365e-239	768.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1563041_0	1185876.BN8_00862	1.414e-259	826.0	COG0577@1|root,COG0577@2|Bacteria,4P1TM@976|Bacteroidetes,47UF9@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_1563041_4	1237149.C900_04427	1.255e-12	74.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47UBY@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1567261_2	929556.Solca_3456	4.646e-20	91.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,1IRY3@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_1567261_1	1122226.AUHX01000001_gene753	8.193e-71	246.0	COG0797@1|root,COG0797@2|Bacteria,4NSF1@976|Bacteroidetes,1I5I6@117743|Flavobacteriia	976|Bacteroidetes	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
TLS3_k127_1567261_0	1237149.C900_03138	5.327e-253	787.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,47KQV@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
TLS3_k127_1567261_3	1237149.C900_03128	2.423e-08	58.0	COG2208@1|root,COG2208@2|Bacteria,4NJMJ@976|Bacteroidetes,47JNJ@768503|Cytophagia	976|Bacteroidetes	KT	PFAM Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,SpoIIE
TLS3_k127_1567316_0	761193.Runsl_0785	0.0	1239.0	COG3002@1|root,COG3002@2|Bacteria,4NECE@976|Bacteroidetes,47MDY@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
TLS3_k127_1567316_1	929703.KE386491_gene816	4.255e-195	614.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,47NRZ@768503|Cytophagia	976|Bacteroidetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
TLS3_k127_1569795_1	1121904.ARBP01000047_gene1898	3.151e-135	440.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,47JKY@768503|Cytophagia	976|Bacteroidetes	P	C-terminal region of aryl-sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
TLS3_k127_1569795_0	1122605.KB893625_gene2143	6.565e-216	682.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,1IQY0@117747|Sphingobacteriia	976|Bacteroidetes	P	sulfatase	mdsA	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TLS3_k127_1569795_3	485918.Cpin_5080	6.025e-38	149.0	2CDAN@1|root,309X8@2|Bacteria,4NP84@976|Bacteroidetes,1IUB9@117747|Sphingobacteriia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
TLS3_k127_1569795_2	1123248.KB893317_gene4298	1.411e-112	364.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1IWH6@117747|Sphingobacteriia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
TLS3_k127_1571897_0	1123248.KB893321_gene465	2.255e-244	770.0	COG2133@1|root,COG3291@1|root,COG3391@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,4NF7B@976|Bacteroidetes,1IWJV@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PKD
TLS3_k127_1571897_1	1237149.C900_01363	2.848e-17	87.0	2DZQQ@1|root,32VGE@2|Bacteria,4NYQ2@976|Bacteroidetes	976|Bacteroidetes	S	Transmembrane family 220, helix	-	-	-	-	-	-	-	-	-	-	-	-	TMEM220
TLS3_k127_1574576_0	153721.MYP_2567	3.895e-320	998.0	COG1643@1|root,COG1643@2|Bacteria,4NFJ7@976|Bacteroidetes,47KRZ@768503|Cytophagia	976|Bacteroidetes	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
TLS3_k127_1574576_4	1123248.KB893331_gene3762	1.013e-72	251.0	28K10@1|root,2Z9QW@2|Bacteria,4NF8J@976|Bacteroidetes,1ISKT@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4918
TLS3_k127_1574576_1	1120965.AUBV01000001_gene3521	2.445e-220	695.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47KZX@768503|Cytophagia	976|Bacteroidetes	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
TLS3_k127_1574576_3	1124780.ANNU01000019_gene1723	9.175e-214	681.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NEK7@976|Bacteroidetes,47MJ9@768503|Cytophagia	976|Bacteroidetes	L	PFAM Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
TLS3_k127_1574576_2	925409.KI911562_gene299	1.097e-215	681.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1IR8Z@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
TLS3_k127_1578409_1	1120965.AUBV01000008_gene2087	7.769e-35	154.0	COG1629@1|root,COG1629@2|Bacteria,4NMTD@976|Bacteroidetes,47PTS@768503|Cytophagia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
TLS3_k127_1578409_0	1237149.C900_05164	1.766e-121	398.0	COG3250@1|root,COG3250@2|Bacteria,4NE9C@976|Bacteroidetes,47P4Y@768503|Cytophagia	976|Bacteroidetes	G	Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
TLS3_k127_1595878_5	287.DR97_4491	1.169e-56	204.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,1RQNI@1236|Gammaproteobacteria,1YD5U@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
TLS3_k127_1595878_1	929703.KE386491_gene3030	1.095e-174	554.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,47NT6@768503|Cytophagia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_1595878_0	929703.KE386491_gene3029	3.441e-216	681.0	COG0521@1|root,COG0521@2|Bacteria,4NHV5@976|Bacteroidetes,47MJ0@768503|Cytophagia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_2
TLS3_k127_1595878_3	1358423.N180_05045	1.848e-147	480.0	COG3182@1|root,COG3182@2|Bacteria,4NEXX@976|Bacteroidetes,1ISYP@117747|Sphingobacteriia	976|Bacteroidetes	S	PepSY-associated TM region	piuB	-	-	-	-	-	-	-	-	-	-	-	PepSY,PepSY_TM
TLS3_k127_1595878_4	616991.JPOO01000003_gene972	5.055e-116	380.0	COG2207@1|root,COG2207@2|Bacteria,4NEVG@976|Bacteroidetes,1HX26@117743|Flavobacteriia,23GX4@178469|Arenibacter	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
TLS3_k127_1595878_2	1392489.JPOL01000003_gene97	3.405e-170	540.0	COG2133@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	Copper-bind,Cytochrom_C,DUF4980,Glyco_hydro_32C,Glyco_hydro_32N,ThuA
TLS3_k127_1596548_5	1237149.C900_05135	6.373e-37	142.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,47JUQ@768503|Cytophagia	976|Bacteroidetes	C	Electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
TLS3_k127_1596548_2	643867.Ftrac_3399	3.355e-120	389.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,47KZ2@768503|Cytophagia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
TLS3_k127_1596548_6	762903.Pedsa_0774	9.719e-23	100.0	COG0457@1|root,COG0457@2|Bacteria,4PM5D@976|Bacteroidetes,1J0VV@117747|Sphingobacteriia	976|Bacteroidetes	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_6,TPR_8
TLS3_k127_1596548_4	1279009.ADICEAN_02967	5.443e-45	173.0	COG2010@1|root,COG3291@1|root,COG2010@2|Bacteria,COG3291@2|Bacteria,4NV3K@976|Bacteroidetes,47W7K@768503|Cytophagia	976|Bacteroidetes	C	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1596548_0	1237149.C900_05140	8.97e-239	747.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,47JB5@768503|Cytophagia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
TLS3_k127_1596548_1	1237149.C900_05141	1.621e-187	596.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,47JEX@768503|Cytophagia	976|Bacteroidetes	M	Mur ligase middle domain	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_1596548_3	1121904.ARBP01000003_gene6405	1.106e-67	233.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,47N5P@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase III	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
TLS3_k127_1630555_0	1089547.KB913013_gene4105	8.965e-281	872.0	COG2382@1|root,COG2382@2|Bacteria,4NGBK@976|Bacteroidetes,47K7D@768503|Cytophagia	976|Bacteroidetes	P	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
TLS3_k127_1630555_1	1305737.JAFX01000001_gene3277	1.248e-185	584.0	COG1960@1|root,COG1960@2|Bacteria,4NFII@976|Bacteroidetes,47NCG@768503|Cytophagia	976|Bacteroidetes	I	Acyl-CoA dehydrogenase, C-terminal domain	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_1634563_1	929556.Solca_0501	6.243e-13	78.0	COG2304@1|root,COG2304@2|Bacteria,4NKB6@976|Bacteroidetes,1IQFS@117747|Sphingobacteriia	976|Bacteroidetes	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT
TLS3_k127_1634563_0	1202532.FF52_10548	4.724e-14	86.0	COG1520@1|root,COG1520@2|Bacteria,4NMP7@976|Bacteroidetes,1I1N3@117743|Flavobacteriia,2NSZF@237|Flavobacterium	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TLS3_k127_1638114_2	760192.Halhy_4155	5.132e-81	288.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Asp_protease_2,BAAT_C,DLH
TLS3_k127_1638114_0	880073.Calab_3557	3.118e-109	362.0	COG1215@1|root,COG1215@2|Bacteria,2NQN3@2323|unclassified Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4,Glycos_transf_2
TLS3_k127_1638114_1	1349785.BAUG01000012_gene946	4.36e-89	304.0	COG1216@1|root,COG1216@2|Bacteria,4PKBZ@976|Bacteroidetes,1IJBV@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
TLS3_k127_1638114_3	545694.TREPR_0030	2.379e-65	233.0	2B8C0@1|root,321KT@2|Bacteria	2|Bacteria	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
TLS3_k127_1638114_4	760192.Halhy_1530	5.684e-57	204.0	COG1595@1|root,COG1595@2|Bacteria,4NQJE@976|Bacteroidetes,1ISX5@117747|Sphingobacteriia	976|Bacteroidetes	K	SPTR RNA polymerase, sigma-24 subunit, ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
TLS3_k127_1640861_1	1121904.ARBP01000030_gene1934	1.696e-41	154.0	COG1695@1|root,COG1695@2|Bacteria,4P6G7@976|Bacteroidetes,47VZ7@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_1640861_0	1185876.BN8_01424	1.942e-118	396.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1642567_3	643867.Ftrac_1574	2.662e-55	196.0	2BJ0K@1|root,32D95@2|Bacteria,4NQN9@976|Bacteroidetes,47QR4@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1642567_4	745718.JADT01000013_gene1355	2.42e-54	196.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,1I1YS@117743|Flavobacteriia	976|Bacteroidetes	E	Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
TLS3_k127_1642567_1	1189612.A33Q_3768	4.699e-152	488.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,47JR7@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
TLS3_k127_1642567_5	880070.Cycma_2784	1.204e-49	179.0	2BXI1@1|root,32R1C@2|Bacteria,4NR9I@976|Bacteroidetes,47QU5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1642567_2	1237149.C900_04968	9.473e-59	209.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,47QV5@768503|Cytophagia	976|Bacteroidetes	S	Acyl carrier protein phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
TLS3_k127_1642567_7	643867.Ftrac_1600	2.983e-19	93.0	COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes,47R5X@768503|Cytophagia	976|Bacteroidetes	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1642567_0	1237149.C900_04965	2.28e-198	626.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,47MWF@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
TLS3_k127_1642567_6	1122605.KB893643_gene687	6.032e-27	109.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1IQMU@117747|Sphingobacteriia	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
TLS3_k127_1644911_4	269798.CHU_3766	4.933e-33	129.0	COG0564@1|root,COG0564@2|Bacteria,4P103@976|Bacteroidetes,47TWQ@768503|Cytophagia	976|Bacteroidetes	J	RNA pseudouridylate synthase	-	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
TLS3_k127_1644911_0	1237149.C900_04044	2.369e-222	715.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1644911_1	1123248.KB893329_gene4433	8.955e-183	581.0	COG0673@1|root,COG0673@2|Bacteria,4NF9M@976|Bacteroidetes,1IR8X@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_1644911_2	616991.JPOO01000003_gene117	1.752e-104	344.0	COG2303@1|root,COG2303@2|Bacteria,4PNKB@976|Bacteroidetes,1IK82@117743|Flavobacteriia,23H2I@178469|Arenibacter	976|Bacteroidetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_1644911_3	1250232.JQNJ01000001_gene3217	1.898e-104	354.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	pelC	-	-	ko:K21008	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	LpoB
TLS3_k127_1650089_0	485918.Cpin_1990	4.834e-131	422.0	COG0179@1|root,COG0179@2|Bacteria,4NFMZ@976|Bacteroidetes,1IPCE@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
TLS3_k127_1650089_1	1121011.AUCB01000006_gene989	2.868e-110	361.0	COG1028@1|root,COG1028@2|Bacteria,4NH6Y@976|Bacteroidetes,1HXA4@117743|Flavobacteriia,23GTX@178469|Arenibacter	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_1650089_3	1185876.BN8_05686	2.42e-61	216.0	COG1403@1|root,COG1403@2|Bacteria,4NJ0T@976|Bacteroidetes,47MEF@768503|Cytophagia	976|Bacteroidetes	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
TLS3_k127_1650089_2	643867.Ftrac_0059	3.754e-100	332.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,47PND@768503|Cytophagia	976|Bacteroidetes	M	Cell wall-associated hydrolase (invasion-associated protein)	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
TLS3_k127_1650089_4	1237149.C900_04099	1.463e-37	143.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,47PRC@768503|Cytophagia	976|Bacteroidetes	J	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
TLS3_k127_1668353_0	926549.KI421517_gene109	3.792e-166	531.0	COG0477@1|root,COG2814@2|Bacteria,4NEQU@976|Bacteroidetes,47KKT@768503|Cytophagia	976|Bacteroidetes	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_1668353_1	1237149.C900_02616	2.201e-149	497.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NQHU@976|Bacteroidetes,47R06@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_8
TLS3_k127_1668353_3	1304883.KI912532_gene3253	5.189e-18	87.0	2EIBB@1|root,33C2R@2|Bacteria,1NETH@1224|Proteobacteria,2VXET@28216|Betaproteobacteria,2KXHM@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1668353_4	686578.AFFX01000001_gene1382	7.917e-07	52.0	2EGMT@1|root,33ADY@2|Bacteria,1NH3I@1224|Proteobacteria,1SGAI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phospholipase_D-nuclease N-terminal	IV01_13290	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
TLS3_k127_1668353_2	1237149.C900_02612	2.489e-110	364.0	COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,47NTZ@768503|Cytophagia	976|Bacteroidetes	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
TLS3_k127_1698660_2	1124780.ANNU01000064_gene435	4.393e-84	285.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,47K5Q@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
TLS3_k127_1698660_0	1237149.C900_02255	2.411e-218	685.0	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,47M23@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
TLS3_k127_1698660_1	643867.Ftrac_1553	5.534e-115	376.0	COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,47ND4@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
TLS3_k127_1700322_5	1123057.P872_18635	1.352e-85	298.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,47KCA@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
TLS3_k127_1700322_3	926549.KI421517_gene1819	2.12e-125	407.0	COG2084@1|root,COG2084@2|Bacteria,4NEF7@976|Bacteroidetes,47N6M@768503|Cytophagia	976|Bacteroidetes	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	mmsB	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
TLS3_k127_1700322_4	1121904.ARBP01000003_gene6351	1.182e-87	296.0	COG3836@1|root,COG3836@2|Bacteria,4NH2V@976|Bacteroidetes,47JVN@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.20,4.1.2.52,4.1.2.53	ko:K01630,ko:K02510,ko:K12660	ko00051,ko00053,ko00350,ko01120,map00051,map00053,map00350,map01120	-	R01645,R01647,R02261,R02754,R03277	RC00307,RC00435,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
TLS3_k127_1700322_1	234267.Acid_7728	5.775e-149	482.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
TLS3_k127_1700322_0	1340493.JNIF01000004_gene416	1.376e-184	586.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	gudD	-	4.2.1.40	ko:K01706	ko00053,ko01100,map00053,map01100	-	R02752,R08056	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
TLS3_k127_1700322_2	1123277.KB893173_gene1831	3.236e-129	426.0	COG2610@1|root,COG2610@2|Bacteria,4NJ5B@976|Bacteroidetes,47K2S@768503|Cytophagia	976|Bacteroidetes	EG	PFAM Gluconate transporter	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
TLS3_k127_170033_1	1279009.ADICEAN_00025	1.377e-26	111.0	2E3Q4@1|root,32YN3@2|Bacteria,4NVYD@976|Bacteroidetes,47RSR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_170033_0	700598.Niako_3962	1.989e-40	154.0	COG0745@1|root,COG0745@2|Bacteria,4NPID@976|Bacteroidetes	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_170033_2	945713.IALB_2553	0.0002564	48.0	COG0745@1|root,COG0745@2|Bacteria	945713.IALB_2553|-	T	phosphorelay signal transduction system	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	-
TLS3_k127_1701456_2	1279009.ADICEAN_02240	1.018e-31	139.0	COG4251@1|root,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,47JSC@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_1701456_0	1279009.ADICEAN_03485	3.69e-137	442.0	COG0408@1|root,COG0408@2|Bacteria,4NFZS@976|Bacteroidetes,47M0F@768503|Cytophagia	976|Bacteroidetes	H	PFAM coproporphyrinogen III oxidase	hemF	-	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
TLS3_k127_1701456_1	1048983.EL17_19375	5.831e-66	229.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47MZ7@768503|Cytophagia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
TLS3_k127_1710470_7	1237149.C900_02736	1.022e-49	186.0	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,47NDD@768503|Cytophagia	976|Bacteroidetes	S	Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
TLS3_k127_1710470_4	1237149.C900_02736	8.896e-84	289.0	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,47NDD@768503|Cytophagia	976|Bacteroidetes	S	Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
TLS3_k127_1710470_0	1237149.C900_02738	1.314e-224	701.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,47JWG@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
TLS3_k127_1710470_3	1237149.C900_02739	5.187e-100	333.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,47KG0@768503|Cytophagia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
TLS3_k127_1710470_6	485917.Phep_3821	8.948e-62	215.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,1IS85@117747|Sphingobacteriia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
TLS3_k127_1710470_5	1124780.ANNU01000005_gene2506	6.647e-66	243.0	28H89@1|root,2Z7K8@2|Bacteria,4NEKX@976|Bacteroidetes,47M3Y@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1710470_8	1237149.C900_02742	2.599e-41	155.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,47Q35@768503|Cytophagia	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
TLS3_k127_1710470_2	1237149.C900_02744	3.047e-111	372.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,47M0Q@768503|Cytophagia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_2	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
TLS3_k127_1710470_1	1237149.C900_02745	7.325e-190	603.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,47JVA@768503|Cytophagia	976|Bacteroidetes	L	PFAM Helicase conserved C-terminal domain	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N
TLS3_k127_1712098_3	1237149.C900_01193	3.845e-88	299.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,47KM1@768503|Cytophagia	976|Bacteroidetes	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
TLS3_k127_1712098_5	643867.Ftrac_0778	8.485e-25	104.0	2DQ4W@1|root,334SC@2|Bacteria,4NUQX@976|Bacteroidetes,47RZV@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3098)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3098
TLS3_k127_1712098_2	1270196.JCKI01000003_gene1835	2.355e-95	319.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,1IPDJ@117747|Sphingobacteriia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
TLS3_k127_1712098_4	1279009.ADICEAN_02324	9.104e-85	287.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,47P98@768503|Cytophagia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
TLS3_k127_1712098_0	1237149.C900_01189	2.973e-138	445.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,47JNP@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
TLS3_k127_1712098_1	1121104.AQXH01000004_gene95	2.107e-125	411.0	COG0365@1|root,COG0365@2|Bacteria,4NINZ@976|Bacteroidetes,1IPMF@117747|Sphingobacteriia	976|Bacteroidetes	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
TLS3_k127_1716515_3	468059.AUHA01000005_gene2617	5.221e-154	494.0	COG1570@1|root,COG1570@2|Bacteria,4NE64@976|Bacteroidetes,1IRPR@117747|Sphingobacteriia	976|Bacteroidetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
TLS3_k127_1716515_5	382464.ABSI01000010_gene3861	1.024e-55	200.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	yuaD	-	-	-	-	-	-	-	-	-	-	-	MOSC
TLS3_k127_1716515_0	1123248.KB893321_gene481	6.722e-229	734.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia	976|Bacteroidetes	V	TIGRFAM Acidobacterial duplicated orphan permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1716515_4	929562.Emtol_1032	3.166e-133	432.0	COG2055@1|root,COG2055@2|Bacteria,4NGVC@976|Bacteroidetes,47MHU@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	1.1.1.130	ko:K08092	ko00040,ko00053,map00040,map00053	-	R02637,R02639	RC00238	ko00000,ko00001,ko01000	-	-	-	Ldh_2
TLS3_k127_1716515_2	869213.JCM21142_72630	5.607e-198	625.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,47K09@768503|Cytophagia	976|Bacteroidetes	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
TLS3_k127_1716515_6	1168289.AJKI01000001_gene3662	4.047e-40	151.0	COG0347@1|root,COG0347@2|Bacteria,4NQG9@976|Bacteroidetes	976|Bacteroidetes	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
TLS3_k127_1716515_1	1089547.KB913013_gene4153	2.946e-209	657.0	COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,47JBJ@768503|Cytophagia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
TLS3_k127_1716515_7	1189612.A33Q_1171	7.711e-25	113.0	COG0800@1|root,COG0800@2|Bacteria,4NEFY@976|Bacteroidetes,47PM4@768503|Cytophagia	976|Bacteroidetes	G	PFAM KDPG and KHG aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
TLS3_k127_1716515_8	331869.BAL199_28585	0.0006693	43.0	COG0673@1|root,COG0673@2|Bacteria,1MW74@1224|Proteobacteria,2TSFH@28211|Alphaproteobacteria,4BSB2@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_1719329_2	485918.Cpin_6021	8.419e-76	257.0	COG3832@1|root,COG3832@2|Bacteria,4NPE8@976|Bacteroidetes,1IVFA@117747|Sphingobacteriia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_1719329_1	509635.N824_18585	6.04e-107	351.0	COG0262@1|root,COG0262@2|Bacteria,4P1JF@976|Bacteroidetes	976|Bacteroidetes	H	bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
TLS3_k127_1719329_0	616991.JPOO01000001_gene4305	8.157e-229	719.0	COG4636@1|root,COG4636@2|Bacteria,4NFKR@976|Bacteroidetes,1I0DS@117743|Flavobacteriia,23G9P@178469|Arenibacter	976|Bacteroidetes	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS3_k127_1719329_3	1123248.KB893333_gene2824	1.577e-57	205.0	2AY99@1|root,31QBJ@2|Bacteria,4NNSA@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
TLS3_k127_1719329_4	1237149.C900_00839	8.132e-48	175.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_1736345_9	196490.AUEZ01000005_gene3531	7.886e-10	59.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,3JUJC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
TLS3_k127_1736345_10	1237149.C900_00877	1.996e-05	51.0	COG2114@1|root,COG2114@2|Bacteria,4NG5A@976|Bacteroidetes,47QPA@768503|Cytophagia	976|Bacteroidetes	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
TLS3_k127_1736345_0	468059.AUHA01000002_gene1358	2.209e-144	469.0	2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,1IPF3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1736345_2	1120965.AUBV01000006_gene2152	4.66e-129	421.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,47N6X@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TLS3_k127_1736345_3	1380600.AUYN01000010_gene883	2.443e-94	321.0	COG0457@1|root,COG0457@2|Bacteria,4NEYK@976|Bacteroidetes,1I0QJ@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911,TPR_2,TPR_8
TLS3_k127_1736345_1	760192.Halhy_5822	1.834e-130	423.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes	976|Bacteroidetes	G	Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_1736345_4	391603.FBALC1_09522	4.946e-73	254.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1I0QN@117743|Flavobacteriia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_1736345_8	1237149.C900_00064	4.664e-11	74.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Reg_prop,Response_reg,Y_Y_Y
TLS3_k127_1736345_5	1131812.JQMS01000001_gene810	4.909e-63	225.0	2DBBT@1|root,2Z8AC@2|Bacteria,4NIRZ@976|Bacteroidetes,1HZMZ@117743|Flavobacteriia,2NWUU@237|Flavobacterium	976|Bacteroidetes	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
TLS3_k127_1736345_11	471855.Shel_11290	4.567e-05	47.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4CX0G@84998|Coriobacteriia	84998|Coriobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_1742717_2	876044.IMCC3088_1736	7.527e-28	118.0	COG1472@1|root,COG1472@2|Bacteria,1N0Q4@1224|Proteobacteria,1RNK6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	PFAM glycoside hydrolase family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Glyco_hydro_3,Glyco_hydro_3_C
TLS3_k127_1742717_1	1237149.C900_05029	1.38e-83	286.0	COG2114@1|root,COG2114@2|Bacteria,4NR9E@976|Bacteroidetes,47V42@768503|Cytophagia	976|Bacteroidetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Guanylate_cyc
TLS3_k127_1742717_0	983544.Lacal_2774	2.996e-147	485.0	COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,4NHVF@976|Bacteroidetes,1HZ8C@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2
TLS3_k127_1744175_2	1454007.JAUG01000043_gene35	7.149e-103	336.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1IPB5@117747|Sphingobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
TLS3_k127_1744175_3	1237149.C900_04652	5.67e-59	208.0	COG1846@1|root,COG1846@2|Bacteria,4NNK7@976|Bacteroidetes,47QHS@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
TLS3_k127_1744175_0	1123057.P872_12935	0.0	1082.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47JK5@768503|Cytophagia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_1744175_1	1237149.C900_03443	6.263e-117	385.0	COG1729@1|root,COG1729@2|Bacteria,4PKMW@976|Bacteroidetes,47JRZ@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
TLS3_k127_1745750_1	1296416.JACB01000001_gene3301	7.968e-80	280.0	COG0457@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
TLS3_k127_1745750_0	41431.PCC8801_0005	1.762e-90	304.0	COG2020@1|root,COG2020@2|Bacteria,1G4HN@1117|Cyanobacteria,3KGIV@43988|Cyanothece	1117|Cyanobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
TLS3_k127_1745750_2	1178825.ALIH01000001_gene2542	3.884e-50	190.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1HY9W@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
TLS3_k127_1747718_4	1185876.BN8_01413	7.419e-71	247.0	COG4319@1|root,COG4319@2|Bacteria,4P8P0@976|Bacteroidetes	976|Bacteroidetes	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
TLS3_k127_1747718_6	485918.Cpin_6506	3.362e-42	164.0	COG4099@1|root,COG4099@2|Bacteria,4NFSH@976|Bacteroidetes,1IR5D@117747|Sphingobacteriia	976|Bacteroidetes	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase,Peptidase_S9
TLS3_k127_1747718_2	1123277.KB893195_gene5659	2.428e-129	423.0	COG2972@1|root,COG2972@2|Bacteria,4NIRC@976|Bacteroidetes,47RFE@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
TLS3_k127_1747718_3	1121904.ARBP01000037_gene2066	3.152e-94	315.0	COG3279@1|root,COG3279@2|Bacteria,4NF8U@976|Bacteroidetes,47Q2C@768503|Cytophagia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_1747718_1	153721.MYP_1573	1.843e-214	676.0	COG3344@1|root,COG3344@2|Bacteria,4NGJQ@976|Bacteroidetes,47KTU@768503|Cytophagia	976|Bacteroidetes	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
TLS3_k127_1747718_0	153721.MYP_1574	1.647e-276	858.0	COG2345@1|root,COG2345@2|Bacteria,4NJ9W@976|Bacteroidetes,47JZT@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
TLS3_k127_1747718_5	153721.MYP_1575	3.201e-52	188.0	COG3831@1|root,COG3831@2|Bacteria,4NKES@976|Bacteroidetes,47NMY@768503|Cytophagia	976|Bacteroidetes	S	Proposed nucleic acid binding domain	-	-	-	-	-	-	-	-	-	-	-	-	WGR
TLS3_k127_1748990_9	1123057.P872_05730	4.974e-22	95.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,47M4A@768503|Cytophagia	976|Bacteroidetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
TLS3_k127_1748990_7	1237149.C900_03472	9.481e-32	126.0	COG4980@1|root,COG4980@2|Bacteria,4NVHP@976|Bacteroidetes,47RXK@768503|Cytophagia	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
TLS3_k127_1748990_4	1237149.C900_03471	2.433e-59	211.0	2CG1Y@1|root,31EK1@2|Bacteria,4NUTU@976|Bacteroidetes,47XYM@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
TLS3_k127_1748990_8	153721.MYP_4133	2.706e-28	116.0	COG1862@1|root,COG1862@2|Bacteria,4NUT4@976|Bacteroidetes,47R3A@768503|Cytophagia	976|Bacteroidetes	U	TIGRFAM preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
TLS3_k127_1748990_5	643867.Ftrac_1918	6.151e-50	189.0	COG4856@1|root,COG4856@2|Bacteria,4NK5K@976|Bacteroidetes,47K4N@768503|Cytophagia	976|Bacteroidetes	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1748990_3	1124780.ANNU01000018_gene1651	3.091e-64	227.0	COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,47P6S@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
TLS3_k127_1748990_1	700598.Niako_2567	3.029e-114	380.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IQN0@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
TLS3_k127_1748990_0	700598.Niako_2568	0.0	1457.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IP63@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bepE_4	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
TLS3_k127_1748990_2	929713.NIASO_00625	5.187e-110	371.0	COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,1INTW@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_1748990_6	929703.KE386491_gene137	5.524e-41	160.0	2DNJ8@1|root,32XSA@2|Bacteria,4NNQ9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
TLS3_k127_1750838_1	504472.Slin_2052	1.56e-80	273.0	COG0007@1|root,COG0007@2|Bacteria,4NFVR@976|Bacteroidetes,47JQG@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM Uroporphyrin-III C-methyltransferase	-	-	2.1.1.107,4.2.1.75	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
TLS3_k127_1750838_0	313606.M23134_04900	3.008e-279	874.0	COG0155@1|root,COG0155@2|Bacteria,4NENW@976|Bacteroidetes,47MYH@768503|Cytophagia	976|Bacteroidetes	C	Nitrite and sulphite reductase 4Fe-4S	sir	-	1.8.1.2,1.8.7.1	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858,R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	HEPN,NIR_SIR,NIR_SIR_ferr
TLS3_k127_1750838_2	1313301.AUGC01000001_gene1771	2.282e-62	220.0	2CC29@1|root,32RUM@2|Bacteria,4NS83@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
TLS3_k127_1750838_3	880073.Calab_3759	1.122e-54	205.0	2DMDZ@1|root,32QUA@2|Bacteria,2NRD6@2323|unclassified Bacteria	2|Bacteria	S	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
TLS3_k127_1755751_1	1150600.ADIARSV_4003	8.364e-23	101.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_5,Glycos_transf_2
TLS3_k127_1755751_0	1150600.ADIARSV_3999	5.704e-139	454.0	2ADQ2@1|root,313F9@2|Bacteria,4NI26@976|Bacteroidetes,1IWNY@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1756329_1	945713.IALB_1958	3.863e-160	517.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	glgX	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
TLS3_k127_1756329_0	1121904.ARBP01000002_gene6936	2.621e-191	619.0	COG0577@1|root,COG0577@2|Bacteria,4NM3D@976|Bacteroidetes,47JF6@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1764431_1	929703.KE386492_gene4269	6.995e-116	382.0	COG0657@1|root,COG0657@2|Bacteria,4NIQ0@976|Bacteroidetes,47JK6@768503|Cytophagia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
TLS3_k127_1764431_0	1237149.C900_05454	2.099e-177	575.0	COG4886@1|root,COG4886@2|Bacteria,4NKMV@976|Bacteroidetes,47XBF@768503|Cytophagia	976|Bacteroidetes	S	Leucine-rich repeat (LRR) protein	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	COR,LRR_4,Roc,TIR_2
TLS3_k127_1775388_4	929556.Solca_1527	5.074e-39	148.0	COG3685@1|root,COG3685@2|Bacteria,4NMCT@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
TLS3_k127_1775388_3	926549.KI421517_gene948	5.356e-59	219.0	COG0628@1|root,COG0628@2|Bacteria,4NFB2@976|Bacteroidetes,47N6Y@768503|Cytophagia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS3_k127_1775388_0	485918.Cpin_6307	8.129e-89	299.0	COG0266@1|root,COG0266@2|Bacteria,4NH8P@976|Bacteroidetes,1IR2V@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA glycosylase AP lyase, H2TH DNA-binding	-	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH
TLS3_k127_1775388_1	1123057.P872_05695	8.452e-81	280.0	COG0457@1|root,COG0457@2|Bacteria,4NJ7M@976|Bacteroidetes,47N78@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_6,TPR_8
TLS3_k127_1775388_2	1121904.ARBP01000025_gene6070	2.013e-80	270.0	COG2327@1|root,COG2327@2|Bacteria,4NH8A@976|Bacteroidetes,47MJD@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
TLS3_k127_1796162_1	1121904.ARBP01000002_gene6936	1.268e-20	107.0	COG0577@1|root,COG0577@2|Bacteria,4NM3D@976|Bacteroidetes,47JF6@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1796162_0	929562.Emtol_2460	3.902e-304	958.0	COG3250@1|root,COG3250@2|Bacteria,4NGZH@976|Bacteroidetes,47M3M@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
TLS3_k127_1797046_0	929562.Emtol_1294	0.0	1267.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47JR2@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_1797046_1	761193.Runsl_2475	7.773e-118	387.0	2DBBU@1|root,2Z8AF@2|Bacteria,4NFUM@976|Bacteroidetes,47JIC@768503|Cytophagia	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_1801512_3	313598.MED152_00905	3.024e-12	66.0	COG0702@1|root,COG0702@2|Bacteria,4NH6G@976|Bacteroidetes,1IGMZ@117743|Flavobacteriia,3VX6K@52959|Polaribacter	976|Bacteroidetes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
TLS3_k127_1801512_2	866536.Belba_2896	5.835e-26	123.0	COG0526@1|root,COG0526@2|Bacteria,4NH2A@976|Bacteroidetes,47RPZ@768503|Cytophagia	976|Bacteroidetes	O	Thiol-disulfide isomerase-like thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
TLS3_k127_1801512_1	504472.Slin_0945	5.059e-40	151.0	COG1695@1|root,COG1695@2|Bacteria,4NS5H@976|Bacteroidetes,47QMA@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_1801512_0	1185876.BN8_01472	5.553e-104	351.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_1827391_2	1237149.C900_00555	1.278e-28	116.0	COG2197@1|root,COG2197@2|Bacteria,4NQSY@976|Bacteroidetes,47QHW@768503|Cytophagia	976|Bacteroidetes	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
TLS3_k127_1827391_1	1237149.C900_00554	1.278e-52	190.0	2CB8S@1|root,30PE6@2|Bacteria,4NU1E@976|Bacteroidetes,47RMQ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
TLS3_k127_1827391_0	1121904.ARBP01000002_gene7293	9.52e-162	522.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1834584_0	1185876.BN8_00464	1e-323	1000.0	COG4225@1|root,COG4225@2|Bacteria,4NG6C@976|Bacteroidetes,47J9H@768503|Cytophagia	976|Bacteroidetes	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
TLS3_k127_1834584_1	760192.Halhy_1895	3.223e-164	523.0	COG4225@1|root,COG4225@2|Bacteria,4NF1N@976|Bacteroidetes,1IP96@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Heparinase II III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
TLS3_k127_1835894_0	1120966.AUBU01000002_gene2217	8.266e-239	771.0	COG3291@1|root,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes,47KMB@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_1835894_1	203119.Cthe_0009	0.0007079	51.0	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,248C6@186801|Clostridia,3WI3K@541000|Ruminococcaceae	186801|Clostridia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD,RHS_repeat
TLS3_k127_1841013_0	925409.KI911562_gene533	4.058e-225	702.0	COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes,1IPQY@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
TLS3_k127_1841013_2	1158294.JOMI01000007_gene405	1.063e-08	63.0	COG1595@1|root,COG1595@2|Bacteria,4NVCP@976|Bacteroidetes,2FTBY@200643|Bacteroidia	976|Bacteroidetes	K	RNA polymerase	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_1841013_1	1123277.KB893208_gene2826	1.684e-173	551.0	COG2382@1|root,COG2382@2|Bacteria,4NHSA@976|Bacteroidetes,47MHN@768503|Cytophagia	976|Bacteroidetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	CBM_48,Esterase
TLS3_k127_1845849_0	700598.Niako_5886	4.248e-218	686.0	COG1056@1|root,COG1056@2|Bacteria,4NKB5@976|Bacteroidetes,1IVBD@117747|Sphingobacteriia	976|Bacteroidetes	H	cytidyltransferase-related domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1845849_5	1296416.JACB01000031_gene2556	7.407e-107	356.0	COG1397@1|root,COG1397@2|Bacteria,4NF7H@976|Bacteroidetes,1HXII@117743|Flavobacteriia,2YK6T@290174|Aquimarina	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
TLS3_k127_1845849_3	869213.JCM21142_3910	3.159e-118	388.0	COG0061@1|root,COG0061@2|Bacteria,4NG3P@976|Bacteroidetes,47M9J@768503|Cytophagia	976|Bacteroidetes	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
TLS3_k127_1845849_2	1517682.HW49_00855	3.034e-148	476.0	COG0330@1|root,COG0330@2|Bacteria,4NHKT@976|Bacteroidetes	976|Bacteroidetes	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TLS3_k127_1845849_7	929556.Solca_4119	1.623e-50	183.0	2BW7J@1|root,33W87@2|Bacteria,4P3QE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1845849_1	929556.Solca_4118	5.087e-209	659.0	COG1488@1|root,COG1488@2|Bacteria,4NGVU@976|Bacteroidetes,1IS54@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Nicotinate phosphoribosyltransferase (NAPRTase) family	nadV	-	2.4.2.12	ko:K03462	ko00760,ko01100,ko04621,map00760,map01100,map04621	-	R01271	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
TLS3_k127_1845849_4	714943.Mucpa_0973	3.248e-117	385.0	COG1051@1|root,COG1056@1|root,COG1051@2|Bacteria,COG1056@2|Bacteria,4NHID@976|Bacteroidetes,1IV6U@117747|Sphingobacteriia	976|Bacteroidetes	FH	pfam nudix	-	-	2.7.7.1	ko:K13522	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
TLS3_k127_1845849_6	1279009.ADICEAN_00873	1.172e-98	327.0	COG1051@1|root,COG1051@2|Bacteria,4NH28@976|Bacteroidetes,47P8V@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
TLS3_k127_1845849_8	649349.Lbys_0121	6.594e-33	131.0	COG1943@1|root,COG1943@2|Bacteria,4NNFK@976|Bacteroidetes,47PUJ@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
TLS3_k127_1847557_0	1288963.ADIS_0344	9.986e-177	561.0	COG3616@1|root,COG3616@2|Bacteria	2|Bacteria	E	Alanine racemase, N-terminal domain	dhaa	-	4.1.2.42,4.1.3.41	ko:K18425,ko:K19967	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
TLS3_k127_1847557_1	504472.Slin_0410	1.883e-52	190.0	COG1670@1|root,COG1670@2|Bacteria,4NNZZ@976|Bacteroidetes,47QMT@768503|Cytophagia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TLS3_k127_1870938_0	1237149.C900_01327	9.456e-228	711.0	COG0111@1|root,COG0560@1|root,COG0111@2|Bacteria,COG0560@2|Bacteria,4NDVN@976|Bacteroidetes,47MQ2@768503|Cytophagia	976|Bacteroidetes	EH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,HAD
TLS3_k127_1870938_1	1237149.C900_02546	4.576e-124	407.0	COG1932@1|root,COG1932@2|Bacteria,4PKN4@976|Bacteroidetes,47J9A@768503|Cytophagia	976|Bacteroidetes	EH	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	-	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
TLS3_k127_1870938_2	504472.Slin_0974	1.106e-84	283.0	COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,47N5B@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_1870938_5	1121481.AUAS01000001_gene4645	0.0001707	49.0	2DKYE@1|root,32UFY@2|Bacteria,4NU6C@976|Bacteroidetes,47R7T@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1870938_3	1279009.ADICEAN_03728	4.718e-18	90.0	2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,47R28@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1870938_4	1250005.PHEL85_1251	2.911e-17	92.0	2F4EN@1|root,33X4W@2|Bacteria,4P3J2@976|Bacteroidetes,1I902@117743|Flavobacteriia,3VWTF@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_18898_1	153721.MYP_47	4.889e-143	462.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,47KNW@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
TLS3_k127_18898_2	1121904.ARBP01000012_gene1217	1.1e-38	147.0	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,47R4H@768503|Cytophagia	976|Bacteroidetes	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
TLS3_k127_18898_0	1237149.C900_00543	3.028e-153	500.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CHU_C,DUF285,LRR_5,PKD,Peptidase_M43,fn3
TLS3_k127_1903610_2	926549.KI421517_gene310	1.075e-47	178.0	2CIC2@1|root,32S7R@2|Bacteria,4NTW2@976|Bacteroidetes,47Q8B@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
TLS3_k127_1903610_1	1048983.EL17_21855	2.813e-80	271.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
TLS3_k127_1903610_0	1454007.JAUG01000028_gene4465	3.163e-159	509.0	COG1262@1|root,COG1262@2|Bacteria,4NF01@976|Bacteroidetes,1IRJM@117747|Sphingobacteriia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	egtB	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
TLS3_k127_1903610_3	643867.Ftrac_3143	2.581e-39	151.0	COG4301@1|root,COG4301@2|Bacteria,4NEFC@976|Bacteroidetes,47KDA@768503|Cytophagia	976|Bacteroidetes	S	Histidine-specific methyltransferase, SAM-dependent	egtD	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
TLS3_k127_1904347_6	866536.Belba_3316	7.682e-91	304.0	COG2234@1|root,COG2234@2|Bacteria,4NEHY@976|Bacteroidetes,47NK2@768503|Cytophagia	976|Bacteroidetes	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
TLS3_k127_1904347_7	929703.KE386491_gene3606	3.037e-80	277.0	COG1073@1|root,COG1073@2|Bacteria,4NNXQ@976|Bacteroidetes,47PV9@768503|Cytophagia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_1904347_0	1237149.C900_02674	7.426e-219	691.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,47JTG@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
TLS3_k127_1904347_1	929703.KE386491_gene3868	3.585e-192	603.0	COG2355@1|root,COG2355@2|Bacteria,4NDYZ@976|Bacteroidetes,47JHU@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
TLS3_k127_1904347_5	1123248.KB893315_gene3085	1.118e-131	430.0	COG3616@1|root,COG3616@2|Bacteria,4NF5K@976|Bacteroidetes,1IPIR@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Alanine racemase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
TLS3_k127_1904347_8	509635.N824_27520	1.124e-75	256.0	COG0251@1|root,COG0251@2|Bacteria,4NMAM@976|Bacteroidetes,1IS1P@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
TLS3_k127_1904347_9	68219.JNXI01000007_gene1838	2.988e-27	115.0	COG4319@1|root,COG4319@2|Bacteria,2IMG5@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
TLS3_k127_1904347_4	700598.Niako_7264	3.534e-163	524.0	COG2610@1|root,COG2610@2|Bacteria,4NFBD@976|Bacteroidetes,1IPQN@117747|Sphingobacteriia	976|Bacteroidetes	EG	COGs COG2610 H gluconate symporter and related permease	gntT	-	-	ko:K06155	-	-	-	-	ko00000,ko02000	2.A.8.1.4	-	-	GntP_permease
TLS3_k127_1904347_3	1237149.C900_05642	8.822e-171	542.0	COG0332@1|root,COG0332@2|Bacteria,4NFIN@976|Bacteroidetes,47JAR@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
TLS3_k127_1904347_2	1185876.BN8_06544	4.576e-183	578.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,4NF3R@976|Bacteroidetes,47N7W@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4,Peptidase_M1
TLS3_k127_1908137_3	714943.Mucpa_4122	3.467e-212	664.0	COG1069@1|root,COG1069@2|Bacteria,4NEFQ@976|Bacteroidetes,1IQ36@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
TLS3_k127_1908137_5	926549.KI421517_gene1213	1.771e-128	412.0	COG0235@1|root,COG0235@2|Bacteria,4NGMP@976|Bacteroidetes,47MSX@768503|Cytophagia	976|Bacteroidetes	G	PFAM Class II Aldolase and Adducin N-terminal domain	araD	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
TLS3_k127_1908137_0	1123248.KB893323_gene1581	0.0	1028.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,1IR7T@117747|Sphingobacteriia	976|Bacteroidetes	S	coagulation factor 5 8 type	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
TLS3_k127_1908137_2	714943.Mucpa_4125	3.915e-273	845.0	COG2160@1|root,COG2160@2|Bacteria,4NHGG@976|Bacteroidetes,1IPX0@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
TLS3_k127_1908137_1	760192.Halhy_3881	2.375e-281	871.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1IVD1@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
TLS3_k127_1908137_8	925409.KI911562_gene241	1.076e-105	347.0	COG1051@1|root,COG1051@2|Bacteria,4NH28@976|Bacteroidetes,1IP93@117747|Sphingobacteriia	976|Bacteroidetes	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_1908137_9	761193.Runsl_3853	1.778e-41	154.0	COG3254@1|root,COG3254@2|Bacteria,4NQAA@976|Bacteroidetes,47QI3@768503|Cytophagia	976|Bacteroidetes	S	L-rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
TLS3_k127_1908137_6	714943.Mucpa_3673	1.97e-120	392.0	COG3618@1|root,COG3618@2|Bacteria,4NFGB@976|Bacteroidetes,1INSJ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
TLS3_k127_1908137_4	1123277.KB893217_gene4603	2.052e-132	425.0	COG1028@1|root,COG1028@2|Bacteria,4NH6R@976|Bacteroidetes,47KYG@768503|Cytophagia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K18333	ko00051,ko01120,map00051,map01120	-	R08926	RC00066	ko00000,ko00001	-	-	-	adh_short_C2
TLS3_k127_1908137_7	1270193.JARP01000001_gene2794	3.699e-108	351.0	COG3828@1|root,COG3828@2|Bacteria,4NI7K@976|Bacteroidetes,1ICTG@117743|Flavobacteriia,2NUMG@237|Flavobacterium	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
TLS3_k127_1914976_3	153721.MYP_1091	2.018e-18	85.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,47KC2@768503|Cytophagia	976|Bacteroidetes	K	RNA polymerase, sigma-54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
TLS3_k127_1914976_0	866536.Belba_1914	1.195e-230	722.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,47JG8@768503|Cytophagia	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
TLS3_k127_1914976_2	1406840.Q763_02140	2.241e-29	129.0	COG0589@1|root,COG0589@2|Bacteria,4NHXF@976|Bacteroidetes,1HY7W@117743|Flavobacteriia,2P08F@237|Flavobacterium	976|Bacteroidetes	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_1914976_1	1118054.CAGW01000015_gene4585	1.775e-34	134.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,4HA1R@91061|Bacilli,26UBS@186822|Paenibacillaceae	91061|Bacilli	E	Threonine aldolase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
TLS3_k127_1915789_4	398767.Glov_0611	3.004e-53	189.0	COG1803@1|root,COG1803@2|Bacteria,1RD3D@1224|Proteobacteria,42SPC@68525|delta/epsilon subdivisions,2WP55@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	TIGRFAM Methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
TLS3_k127_1915789_0	1237149.C900_01573	0.0	1009.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,47MKQ@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM competence protein ComEA helix-hairpin-helix repeat region	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
TLS3_k127_1915789_1	675814.VIC_001009	7.1e-265	824.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,1XT97@135623|Vibrionales	135623|Vibrionales	G	Belongs to the GPI family	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
TLS3_k127_1915789_2	643867.Ftrac_3083	1.797e-153	490.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,47M49@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
TLS3_k127_1915789_3	1237149.C900_00618	1.056e-139	450.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,47PAF@768503|Cytophagia	976|Bacteroidetes	G	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
TLS3_k127_1915789_5	1198114.AciX9_1766	7.692e-07	60.0	COG3011@1|root,COG3011@2|Bacteria,3Y6SA@57723|Acidobacteria,2JMIF@204432|Acidobacteriia	2|Bacteria	S	Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
TLS3_k127_1920273_0	1123248.KB893338_gene2306	2.178e-104	357.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IRGG@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_1933586_2	1137281.D778_00141	1.898e-60	214.0	COG0006@1|root,COG0006@2|Bacteria,4NI0S@976|Bacteroidetes,1HZX1@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
TLS3_k127_1933586_4	1237149.C900_01746	2.736e-14	74.0	2ECIG@1|root,336GN@2|Bacteria,4NX5X@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1933586_1	1237149.C900_01745	7.772e-61	211.0	COG0234@1|root,COG0234@2|Bacteria,4NRE1@976|Bacteroidetes,47Q9W@768503|Cytophagia	976|Bacteroidetes	O	Chaperonin 10 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cpn10
TLS3_k127_1933586_0	1123277.KB893197_gene6125	1.702e-147	480.0	COG0526@1|root,COG1225@1|root,COG0526@2|Bacteria,COG1225@2|Bacteria,4NMEK@976|Bacteroidetes,47K5E@768503|Cytophagia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
TLS3_k127_1933586_3	929703.KE386491_gene2989	1.012e-24	106.0	COG1322@1|root,COG1322@2|Bacteria,4PJCR@976|Bacteroidetes,47MZK@768503|Cytophagia	976|Bacteroidetes	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
TLS3_k127_1942140_2	1123248.KB893370_gene5011	4.575e-31	122.0	COG4299@1|root,COG4299@2|Bacteria,4NGKU@976|Bacteroidetes,1IQII@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
TLS3_k127_1942140_1	880071.Fleli_1917	3.123e-75	265.0	COG4421@1|root,COG4421@2|Bacteria,4NVD4@976|Bacteroidetes,47R51@768503|Cytophagia	976|Bacteroidetes	G	Protein of unknown function (DUF563)	-	-	-	-	-	-	-	-	-	-	-	-	DUF563
TLS3_k127_1942140_0	1237149.C900_04628	2.299e-106	368.0	COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,47NCY@768503|Cytophagia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
TLS3_k127_1942140_3	616991.JPOO01000001_gene4166	5.986e-20	92.0	COG2755@1|root,COG2755@2|Bacteria,4NIBN@976|Bacteroidetes,1I038@117743|Flavobacteriia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS3_k127_1944194_1	926549.KI421517_gene2412	4.68e-141	461.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_1944194_0	926549.KI421517_gene2419	6.909e-173	560.0	COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_1946626_2	880070.Cycma_4778	1.796e-88	301.0	COG3394@1|root,COG3394@2|Bacteria,4NFY5@976|Bacteroidetes,47TX0@768503|Cytophagia	976|Bacteroidetes	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
TLS3_k127_1946626_1	1089547.KB913013_gene2165	1.453e-96	326.0	COG2603@1|root,COG2603@2|Bacteria,4NH7W@976|Bacteroidetes,47KFW@768503|Cytophagia	976|Bacteroidetes	S	Rhodanese Homology Domain	-	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
TLS3_k127_1946626_0	1356852.N008_06245	9.042e-137	441.0	COG0709@1|root,COG0709@2|Bacteria,4NI4R@976|Bacteroidetes,47JJA@768503|Cytophagia	976|Bacteroidetes	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
TLS3_k127_1949467_0	1121481.AUAS01000014_gene2341	1.005e-98	328.0	28J3W@1|root,2Z900@2|Bacteria,4NG4R@976|Bacteroidetes,47NT0@768503|Cytophagia	976|Bacteroidetes	S	pfam nipsnap	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
TLS3_k127_1949467_1	700598.Niako_6312	3.934e-91	304.0	COG0744@1|root,COG0744@2|Bacteria,4NF90@976|Bacteroidetes,1IRZ0@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
TLS3_k127_1949467_2	743722.Sph21_1029	6.831e-49	177.0	COG1069@1|root,COG1069@2|Bacteria,4NEFQ@976|Bacteroidetes,1IQ36@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
TLS3_k127_19604_3	717772.THIAE_08480	0.0007529	46.0	COG0642@1|root,COG2205@2|Bacteria	717772.THIAE_08480|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_19604_0	1288963.ADIS_2371	1.001e-240	765.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47XI5@768503|Cytophagia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
TLS3_k127_19604_1	234267.Acid_7218	7.272e-54	193.0	COG2080@1|root,COG2080@2|Bacteria,3Y5EJ@57723|Acidobacteria	57723|Acidobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
TLS3_k127_19604_2	760192.Halhy_4948	3.493e-52	187.0	COG2259@1|root,COG2259@2|Bacteria,4P48I@976|Bacteroidetes	976|Bacteroidetes	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
TLS3_k127_197215_7	1178825.ALIH01000026_gene1866	2.242e-05	48.0	2DEFQ@1|root,2ZMUG@2|Bacteria,4P7CS@976|Bacteroidetes,1IBT1@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_197215_0	1237149.C900_03200	0.0	1208.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,47JV4@768503|Cytophagia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
TLS3_k127_197215_2	1048983.EL17_13630	2.859e-76	260.0	COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes,47P8Z@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
TLS3_k127_197215_3	1237149.C900_03203	1.872e-73	252.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,47PE9@768503|Cytophagia	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
TLS3_k127_197215_6	1005090.BAKON_538	1.321e-05	56.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RRKU@1236|Gammaproteobacteria,37D78@32199|Buchnera	1236|Gammaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	fkpA	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
TLS3_k127_197215_5	643867.Ftrac_2532	3.301e-14	83.0	COG0545@1|root,COG0545@2|Bacteria,4NQJS@976|Bacteroidetes	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
TLS3_k127_197215_4	1121481.AUAS01000008_gene3052	1.279e-37	153.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,47KIJ@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiB	-	5.2.1.8	ko:K01802,ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
TLS3_k127_197215_1	1279009.ADICEAN_02596	6.974e-134	433.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,47JVC@768503|Cytophagia	976|Bacteroidetes	S	phosphoesterase RecJ domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
TLS3_k127_1984817_1	761193.Runsl_2668	8.359e-41	152.0	COG2133@1|root,COG4654@1|root,COG2133@2|Bacteria,COG4654@2|Bacteria,4NEMM@976|Bacteroidetes,47KPY@768503|Cytophagia	976|Bacteroidetes	CG	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TLS3_k127_1984817_0	760192.Halhy_5254	1.362e-207	656.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1IW8M@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
TLS3_k127_1984817_2	1237149.C900_04443	7.227e-19	89.0	2EJD3@1|root,33D44@2|Bacteria,4NP3M@976|Bacteroidetes,47PW7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
TLS3_k127_1987388_0	1122176.KB903536_gene1741	1.472e-277	866.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,1IVI6@117747|Sphingobacteriia	976|Bacteroidetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
TLS3_k127_1987388_1	485917.Phep_3657	1.476e-118	387.0	COG0101@1|root,COG0101@2|Bacteria,4NKT7@976|Bacteroidetes,1IRQ8@117747|Sphingobacteriia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	-	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
TLS3_k127_1987388_2	1124780.ANNU01000020_gene3305	1.074e-61	220.0	COG5276@1|root,COG5276@2|Bacteria,4NIJE@976|Bacteroidetes,47N1R@768503|Cytophagia	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
TLS3_k127_1997037_4	1131812.JQMS01000001_gene2168	1.319e-46	169.0	COG2220@1|root,COG2220@2|Bacteria,4NENZ@976|Bacteroidetes,1HWY9@117743|Flavobacteriia,2NSUU@237|Flavobacterium	976|Bacteroidetes	S	Beta-lactamase superfamily domain	romA	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
TLS3_k127_1997037_1	946077.W5A_08142	3.166e-63	224.0	COG1670@1|root,COG1670@2|Bacteria,4NNE4@976|Bacteroidetes,1I1AJ@117743|Flavobacteriia	976|Bacteroidetes	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TLS3_k127_1997037_3	468059.AUHA01000002_gene1279	2.565e-55	196.0	COG0346@1|root,COG0346@2|Bacteria,4NQCJ@976|Bacteroidetes,1IXZD@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_1997037_0	1408445.JHXP01000014_gene1446	8.759e-122	401.0	COG2170@1|root,COG2170@2|Bacteria,1MX4N@1224|Proteobacteria,1RRZ1@1236|Gammaproteobacteria,1JCFE@118969|Legionellales	118969|Legionellales	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
TLS3_k127_1997037_2	1237149.C900_01149	1.535e-59	209.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia	976|Bacteroidetes	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS3_k127_2004309_0	1237149.C900_05632	6.647e-87	301.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,47K9M@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
TLS3_k127_2004309_1	1086011.HJ01_03085	4.889e-52	192.0	COG1835@1|root,COG1835@2|Bacteria,4NJVW@976|Bacteroidetes,1IIRZ@117743|Flavobacteriia	976|Bacteroidetes	I	Acyltransferase family	oatA	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS3_k127_2004481_0	1121904.ARBP01000002_gene7112	0.0	1025.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47JHW@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_2006957_1	746697.Aeqsu_3164	6.951e-30	124.0	2EQG1@1|root,3309R@2|Bacteria,4NV48@976|Bacteroidetes,1IAJ6@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2006957_0	1121904.ARBP01000010_gene2393	3.978e-177	582.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JYF@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_200741_3	190650.CC_1631	1.736e-48	173.0	COG1082@1|root,COG1082@2|Bacteria,1MVSJ@1224|Proteobacteria,2TV5J@28211|Alphaproteobacteria,2KFAP@204458|Caulobacterales	204458|Caulobacterales	G	AP endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
TLS3_k127_200741_4	509635.N824_17055	5.881e-28	118.0	COG4654@1|root,COG4654@2|Bacteria,4NSJC@976|Bacteroidetes,1ITX4@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
TLS3_k127_200741_1	1237149.C900_01360	1.755e-92	309.0	COG2133@1|root,COG4654@1|root,COG2133@2|Bacteria,COG4654@2|Bacteria,4NEMM@976|Bacteroidetes,47KXP@768503|Cytophagia	976|Bacteroidetes	CG	PFAM Cytochrome c, class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,DUF1080,PA14
TLS3_k127_200741_0	761193.Runsl_4304	0.0	1129.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,COG4654@2|Bacteria,4NDVK@976|Bacteroidetes,47MAT@768503|Cytophagia	976|Bacteroidetes	CG	Cytochrome c, class I	-	-	-	ko:K08738,ko:K09992	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	CBM_6,Cytochrom_C,Cytochrome_CBB3,GSDH,PKD,ThuA
TLS3_k127_200741_2	926549.KI421517_gene1334	2.312e-75	262.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,47NJ6@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_2009444_0	1237149.C900_02591	1.431e-273	859.0	COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_2009444_1	1279009.ADICEAN_00047	1.452e-219	692.0	COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,4NHGP@976|Bacteroidetes,47TS8@768503|Cytophagia	976|Bacteroidetes	CG	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH
TLS3_k127_2009444_2	760192.Halhy_4304	1.066e-122	398.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1IP9G@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
TLS3_k127_2013410_0	945713.IALB_2766	1.875e-88	297.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
TLS3_k127_2013410_2	1237149.C900_03020	1.087e-61	221.0	COG0500@1|root,COG2226@2|Bacteria,4NICK@976|Bacteroidetes	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_2013410_1	945713.IALB_2765	3.887e-67	238.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	MetW,Methyltransf_11,Methyltransf_25,Methyltransf_31
TLS3_k127_2013410_3	1122176.KB903538_gene1445	2.19e-52	194.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	ermC	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
TLS3_k127_2013410_4	797114.C475_01237	8.612e-17	89.0	COG0438@1|root,arCOG01403@2157|Archaea,2XTRH@28890|Euryarchaeota,24182@183963|Halobacteria	183963|Halobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_2013410_6	1237149.C900_03821	8.707e-08	60.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
TLS3_k127_2013410_5	877455.Metbo_0721	2.214e-08	60.0	COG0438@1|root,arCOG01403@2157|Archaea,2XXCQ@28890|Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_20154_2	643867.Ftrac_1805	6.206e-90	304.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47KYY@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_20154_1	1279009.ADICEAN_01863	8.51e-174	559.0	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,47KSA@768503|Cytophagia	976|Bacteroidetes	S	PFAM RagB SusD domain protein	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_20154_3	1279009.ADICEAN_01864	7.7e-65	237.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_20154_0	385682.AFSL01000009_gene2486	3.11e-225	716.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,2FM8G@200643|Bacteroidia,3XJSW@558415|Marinilabiliaceae	976|Bacteroidetes	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Glycoamylase
TLS3_k127_20154_4	700598.Niako_2271	0.0004293	46.0	COG2823@1|root,COG2823@2|Bacteria,4NJ6H@976|Bacteroidetes	976|Bacteroidetes	S	COGs COG2823 periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
TLS3_k127_2018583_0	1123057.P872_22980	1.993e-254	798.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,47NT6@768503|Cytophagia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_2018583_2	391596.PBAL39_18154	1.824e-48	186.0	COG2207@1|root,COG2207@2|Bacteria,4NEEQ@976|Bacteroidetes,1ITDQ@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, AraC family	pchR	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_2018583_1	471854.Dfer_2115	6.031e-210	662.0	COG0561@1|root,COG0561@2|Bacteria,4PMI0@976|Bacteroidetes,47K0D@768503|Cytophagia	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_2018583_3	1121904.ARBP01000022_gene3523	9.04e-09	56.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47Y2H@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_202540_3	1121957.ATVL01000006_gene2714	6.04e-11	73.0	COG1629@1|root,COG1629@2|Bacteria,4PM9F@976|Bacteroidetes,47YJ8@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
TLS3_k127_202540_2	714943.Mucpa_2691	2.984e-45	170.0	COG0212@1|root,COG0212@2|Bacteria,4NM97@976|Bacteroidetes,1IT2P@117747|Sphingobacteriia	976|Bacteroidetes	H	5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
TLS3_k127_202540_1	643867.Ftrac_1928	1.473e-167	541.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,47JYH@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
TLS3_k127_202540_0	1237149.C900_01759	1.171e-226	707.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,47JJ2@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
TLS3_k127_2031785_2	929713.NIASO_13295	4.514e-169	541.0	COG1541@1|root,COG1541@2|Bacteria,4NGRR@976|Bacteroidetes,1IP0X@117747|Sphingobacteriia	976|Bacteroidetes	H	AMP-binding enzyme	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
TLS3_k127_2031785_4	1047013.AQSP01000059_gene2096	3.085e-32	129.0	COG0736@1|root,COG0736@2|Bacteria,2NPTD@2323|unclassified Bacteria	2|Bacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7,4.2.1.136	ko:K00997,ko:K17758	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS,Carb_kinase
TLS3_k127_2031785_1	929713.NIASO_17950	2.159e-196	626.0	COG0457@1|root,COG0457@2|Bacteria,4PKJM@976|Bacteroidetes,1J0ZM@117747|Sphingobacteriia	976|Bacteroidetes	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
TLS3_k127_2031785_3	491205.JARQ01000005_gene1769	2.105e-148	485.0	COG1233@1|root,COG1233@2|Bacteria,4NG5Y@976|Bacteroidetes,1HZF6@117743|Flavobacteriia,3ZPR1@59732|Chryseobacterium	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.23	ko:K09516	ko00830,map00830	-	R07163	RC01835	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
TLS3_k127_2031785_0	485918.Cpin_1873	0.0	1111.0	COG0204@1|root,COG2227@1|root,COG4258@1|root,COG0204@2|Bacteria,COG2227@2|Bacteria,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,1IQPB@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
TLS3_k127_2054461_0	1237149.C900_00609	4.212e-94	313.0	COG0429@1|root,COG0429@2|Bacteria,4NFGZ@976|Bacteroidetes,47JJP@768503|Cytophagia	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
TLS3_k127_2054461_1	1124780.ANNU01000019_gene1803	9.015e-77	263.0	COG2135@1|root,COG2135@2|Bacteria,4NKPN@976|Bacteroidetes,47MR7@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
TLS3_k127_2054461_2	153721.MYP_4730	1.429e-43	161.0	COG2315@1|root,COG2315@2|Bacteria,4NS6J@976|Bacteroidetes,47R6I@768503|Cytophagia	976|Bacteroidetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
TLS3_k127_2054461_4	1124780.ANNU01000003_gene1416	6.538e-18	83.0	2EGC0@1|root,33A3T@2|Bacteria,4NXPB@976|Bacteroidetes,47SUC@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2066551_3	1237149.C900_04398	9.169e-143	463.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,47ME6@768503|Cytophagia	976|Bacteroidetes	S	PFAM Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
TLS3_k127_2066551_2	504472.Slin_3956	1.766e-212	666.0	COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,47JBJ@768503|Cytophagia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
TLS3_k127_2066551_0	926549.KI421517_gene3143	2.276e-225	703.0	COG4948@1|root,COG4948@2|Bacteria,4NHAW@976|Bacteroidetes,47MU8@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
TLS3_k127_2066551_4	1237149.C900_00350	8.303e-108	365.0	COG2885@1|root,COG2885@2|Bacteria,4PIU2@976|Bacteroidetes,47SAQ@768503|Cytophagia	976|Bacteroidetes	M	Pfam:DUF3308	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_2066551_5	485918.Cpin_0221	1.645e-88	296.0	COG0500@1|root,COG2226@2|Bacteria,4NNUK@976|Bacteroidetes,1IUJG@117747|Sphingobacteriia	976|Bacteroidetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
TLS3_k127_2066551_1	761193.Runsl_2879	8.299e-214	670.0	COG0673@1|root,COG0673@2|Bacteria,4NDYI@976|Bacteroidetes,47NPG@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_2066551_6	714943.Mucpa_7104	3.526e-07	53.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_2,TonB_C
TLS3_k127_2068144_1	761193.Runsl_3676	9.621e-42	156.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,47KD4@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
TLS3_k127_2068144_3	860228.Ccan_00370	7.795e-17	81.0	COG0607@1|root,COG0607@2|Bacteria,4NRYX@976|Bacteroidetes,1I3CK@117743|Flavobacteriia,1EQQ0@1016|Capnocytophaga	976|Bacteroidetes	P	Rhodanese-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS3_k127_2068144_2	517418.Ctha_2510	1.765e-29	125.0	COG3258@1|root,COG3258@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3,DUF3365
TLS3_k127_2068144_0	755732.Fluta_2865	2.939e-66	233.0	COG0526@1|root,COG0607@1|root,COG0526@2|Bacteria,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,1I51Q@117743|Flavobacteriia,2PC0A@246874|Cryomorphaceae	976|Bacteroidetes	COP	COGs COG0607 Rhodanese-related sulfurtransferase	glpE	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Thioredoxin
TLS3_k127_2072763_2	1237149.C900_04724	4.253e-38	145.0	COG1624@1|root,COG1624@2|Bacteria,4NG3Z@976|Bacteroidetes,47JT6@768503|Cytophagia	976|Bacteroidetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
TLS3_k127_2072763_0	153721.MYP_3768	1.33e-321	1018.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NKC3@976|Bacteroidetes,47NP5@768503|Cytophagia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
TLS3_k127_2072763_4	866536.Belba_0095	3.576e-05	52.0	28WX7@1|root,2ZIWD@2|Bacteria,4P8MZ@976|Bacteroidetes,47WMD@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2072763_1	1237149.C900_04723	9.78e-213	665.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,47MGP@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_2072763_3	1237149.C900_04722	2.138e-15	80.0	2EHKD@1|root,33BC6@2|Bacteria,4NXIJ@976|Bacteroidetes,47SW0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2087827_2	1279009.ADICEAN_02104	1.32e-43	167.0	COG5395@1|root,COG5395@2|Bacteria,4NSVW@976|Bacteroidetes,47XVK@768503|Cytophagia	976|Bacteroidetes	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
TLS3_k127_2087827_0	1123057.P872_15440	1.632e-224	704.0	COG4784@1|root,COG4784@2|Bacteria,4PM59@976|Bacteroidetes,47MK2@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TLS3_k127_2087827_4	1408473.JHXO01000009_gene3433	2.665e-20	98.0	2E9C0@1|root,333JQ@2|Bacteria,4NVAR@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2087827_3	1408433.JHXV01000009_gene1250	1.679e-32	147.0	COG4935@1|root,COG4935@2|Bacteria,4PP7N@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2087827_1	927658.AJUM01000042_gene1722	8.01e-45	188.0	COG2353@1|root,COG2911@1|root,COG3210@1|root,COG2353@2|Bacteria,COG2911@2|Bacteria,COG3210@2|Bacteria,4PMJQ@976|Bacteroidetes,2G0DU@200643|Bacteroidia,3XM24@558415|Marinilabiliaceae	976|Bacteroidetes	U	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_209314_0	1237149.C900_02189	2.096e-235	752.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,47KJ6@768503|Cytophagia	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
TLS3_k127_209314_2	929562.Emtol_2974	6.481e-62	219.0	COG1131@1|root,COG1131@2|Bacteria,4NN9G@976|Bacteroidetes,47PDC@768503|Cytophagia	976|Bacteroidetes	V	PFAM ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
TLS3_k127_209314_1	1237149.C900_02185	1.572e-126	408.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,47JJC@768503|Cytophagia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
TLS3_k127_209314_3	1237149.C900_02184	5.885e-24	100.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,47JFB@768503|Cytophagia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
TLS3_k127_2105118_2	1453500.AT05_06155	1.394e-27	117.0	2C7KB@1|root,32RJC@2|Bacteria,4NTM9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2105118_1	1123057.P872_11330	1.352e-170	553.0	COG5492@1|root,COG5492@2|Bacteria,4NH7Q@976|Bacteroidetes,47MBP@768503|Cytophagia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	TIG
TLS3_k127_2105118_0	1189612.A33Q_2664	1.821e-180	586.0	COG1629@1|root,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,47JSW@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
TLS3_k127_2137277_6	1124780.ANNU01000036_gene22	4.9e-26	110.0	COG0640@1|root,COG0640@2|Bacteria,4NUW3@976|Bacteroidetes,47RXB@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
TLS3_k127_2137277_3	761193.Runsl_2267	8.238e-72	245.0	COG2010@1|root,COG2010@2|Bacteria,4NN91@976|Bacteroidetes,47PSM@768503|Cytophagia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
TLS3_k127_2137277_0	1123248.KB893326_gene1394	0.0	1214.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IPTQ@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
TLS3_k127_2137277_2	760192.Halhy_3768	1.394e-104	345.0	28HGK@1|root,2Z7SE@2|Bacteria,4NGDR@976|Bacteroidetes	976|Bacteroidetes	S	Malonate/sodium symporter MadM subunit	-	-	-	-	-	-	-	-	-	-	-	-	MadM
TLS3_k127_2137277_5	929562.Emtol_0620	5.507e-36	141.0	2CAQ0@1|root,32RRS@2|Bacteria,4NRRH@976|Bacteroidetes,47QP4@768503|Cytophagia	976|Bacteroidetes	S	Malonate transporter MadL subunit	-	-	-	-	-	-	-	-	-	-	-	-	MadL
TLS3_k127_2137277_1	761193.Runsl_2171	5.618e-207	655.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,47NTH@768503|Cytophagia	976|Bacteroidetes	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897,ko:K18660	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,PP-binding
TLS3_k127_2137277_4	873513.HMPREF6485_1727	1.073e-51	194.0	COG1119@1|root,COG1119@2|Bacteria,4NEWY@976|Bacteroidetes,2FMN3@200643|Bacteroidia	976|Bacteroidetes	P	ABC-type molybdenum transport system ATPase component photorepair protein PhrA	modF	-	-	ko:K05776	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	-	-	-	ABC_tran
TLS3_k127_2138793_0	1237149.C900_03476	2.97e-197	623.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,47JPX@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
TLS3_k127_2138793_1	1237149.C900_03473	1.951e-73	258.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,47M4A@768503|Cytophagia	976|Bacteroidetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
TLS3_k127_2171527_0	1237149.C900_01780	0.0	1204.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,47KGB@768503|Cytophagia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
TLS3_k127_2171527_1	1408473.JHXO01000005_gene1676	1.761e-81	278.0	COG1051@1|root,COG1051@2|Bacteria,4PMRX@976|Bacteroidetes	976|Bacteroidetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_2171527_2	643867.Ftrac_2200	2.108e-77	263.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,47JGT@768503|Cytophagia	976|Bacteroidetes	S	PFAM LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
TLS3_k127_2171527_3	1185876.BN8_05482	9.04e-16	77.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,47M9W@768503|Cytophagia	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TLS3_k127_2178197_0	468059.AUHA01000006_gene3015	7.064e-240	747.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1IQJT@117747|Sphingobacteriia	976|Bacteroidetes	V	Mate efflux family protein	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
TLS3_k127_2178197_1	1237149.C900_05294	3.365e-86	305.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_2183452_1	886379.AEWI01000122_gene1875	2.313e-37	142.0	COG0446@1|root,COG0446@2|Bacteria,4NEK6@976|Bacteroidetes,2FT9Y@200643|Bacteroidia	976|Bacteroidetes	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_2183452_0	471854.Dfer_4413	9.79e-163	519.0	COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,47M2I@768503|Cytophagia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
TLS3_k127_2191352_8	761193.Runsl_3866	4.948e-51	189.0	2A087@1|root,30NBF@2|Bacteria,4NMD0@976|Bacteroidetes,47P70@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2191352_4	700598.Niako_4169	9.843e-132	445.0	COG1629@1|root,COG4771@2|Bacteria,4NJX5@976|Bacteroidetes	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
TLS3_k127_2191352_5	643867.Ftrac_0613	2.977e-108	370.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HATPase_c,HisKA,PAS_9,Response_reg
TLS3_k127_2191352_6	926549.KI421517_gene2390	3.961e-106	356.0	COG4335@1|root,COG4335@2|Bacteria,4NH5H@976|Bacteroidetes,47MI7@768503|Cytophagia	976|Bacteroidetes	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation,HEAT
TLS3_k127_2191352_9	1237149.C900_04644	5.587e-50	190.0	2BYCP@1|root,2ZAHR@2|Bacteria,4NJ23@976|Bacteroidetes,47NMK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2191352_11	1121904.ARBP01000001_gene5794	4.069e-28	116.0	COG2146@1|root,COG2146@2|Bacteria,4NVFP@976|Bacteroidetes,47S4K@768503|Cytophagia	976|Bacteroidetes	P	Rieske [2Fe-2S] domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
TLS3_k127_2191352_3	1089547.KB913013_gene3846	1.524e-153	498.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47JXE@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_2191352_1	1237149.C900_04632	7.55e-181	576.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47JXE@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_2191352_7	1278073.MYSTI_07026	5.157e-58	205.0	COG0454@1|root,COG0456@2|Bacteria,1RAJC@1224|Proteobacteria,42WFD@68525|delta/epsilon subdivisions,2WS1W@28221|Deltaproteobacteria,2YXI3@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
TLS3_k127_2191352_0	1227739.Hsw_3687	2.22e-293	920.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF70@976|Bacteroidetes,47JEZ@768503|Cytophagia	976|Bacteroidetes	EU	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
TLS3_k127_2191352_2	391596.PBAL39_20054	2.538e-178	569.0	COG0402@1|root,COG0402@2|Bacteria,4NG64@976|Bacteroidetes	976|Bacteroidetes	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
TLS3_k127_2191352_10	421072.IO89_01910	2.194e-45	168.0	COG3741@1|root,COG3741@2|Bacteria,4NIN9@976|Bacteroidetes,1I0JT@117743|Flavobacteriia,3HHQR@358033|Chryseobacterium	976|Bacteroidetes	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
TLS3_k127_2196842_1	1237149.C900_04466	1.014e-87	291.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,47KUD@768503|Cytophagia	976|Bacteroidetes	G	PFAM Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
TLS3_k127_2196842_2	1434325.AZQN01000004_gene1454	3.355e-26	124.0	28J4T@1|root,2Z90P@2|Bacteria,4NHUC@976|Bacteroidetes,47RDH@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
TLS3_k127_2196842_0	1237149.C900_04468	0.0	1019.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,47KVG@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
TLS3_k127_2196842_3	760192.Halhy_1561	5.382e-13	79.0	2AB14@1|root,339IP@2|Bacteria,4NZD5@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2203108_0	1237149.C900_02176	1.349e-268	837.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,47JHX@768503|Cytophagia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
TLS3_k127_2203108_3	1123057.P872_16510	1.226e-39	156.0	2DBXN@1|root,2ZBQR@2|Bacteria,4NN54@976|Bacteroidetes,47PK0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_2203108_2	1237149.C900_02179	1.473e-202	636.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,47J94@768503|Cytophagia	976|Bacteroidetes	E	PFAM Alanine dehydrogenase PNT, C-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
TLS3_k127_2203108_4	153721.MYP_3795	1.495e-39	152.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,47RDS@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised P-loop hydrolase UPF0079	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
TLS3_k127_2203108_1	1237149.C900_02181	4.622e-209	655.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,47KVF@768503|Cytophagia	976|Bacteroidetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
TLS3_k127_2216309_1	504472.Slin_3890	1.403e-161	513.0	COG2141@1|root,COG2141@2|Bacteria,4NHGI@976|Bacteroidetes,47MJ4@768503|Cytophagia	976|Bacteroidetes	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_2216309_0	926549.KI421517_gene1242	2.56e-171	540.0	COG1741@1|root,COG1741@2|Bacteria,4NEV6@976|Bacteroidetes,47JT8@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
TLS3_k127_2216309_2	700598.Niako_6225	1.302e-118	392.0	COG1404@1|root,COG1404@2|Bacteria,4NI53@976|Bacteroidetes,1IV60@117747|Sphingobacteriia	976|Bacteroidetes	M	SPTR Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,Peptidase_S8
TLS3_k127_2216309_3	1122176.KB903543_gene469	4.632e-91	312.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes	976|Bacteroidetes	T	histidine kinase-, DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HTH_18,HisKA,Response_reg,TPR_12,TPR_8
TLS3_k127_2218433_2	1202532.FF52_13881	1.248e-05	47.0	COG0477@1|root,COG0477@2|Bacteria,4NFY1@976|Bacteroidetes,1I0YW@117743|Flavobacteriia,2NSZZ@237|Flavobacterium	976|Bacteroidetes	EGP	MFS transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
TLS3_k127_2218433_1	700598.Niako_6698	1.618e-19	95.0	2EHHG@1|root,33B9E@2|Bacteria,4NXY9@976|Bacteroidetes,1IUFY@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2218433_0	1123248.KB893333_gene2815	3.673e-68	233.0	COG2128@1|root,COG2128@2|Bacteria,4NMGS@976|Bacteroidetes,1IXMN@117747|Sphingobacteriia	976|Bacteroidetes	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
TLS3_k127_2225776_1	1237149.C900_01377	7.454e-45	169.0	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,47NYP@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
TLS3_k127_2225776_0	1237149.C900_01376	1.374e-232	732.0	COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,47MU2@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TLS3_k127_2234287_0	1237149.C900_04420	1.665e-222	698.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4P15I@976|Bacteroidetes,47X8A@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
TLS3_k127_2234287_1	1124780.ANNU01000002_gene1580	4.8e-142	461.0	COG0809@1|root,COG0809@2|Bacteria,4NDZ5@976|Bacteroidetes,47KMT@768503|Cytophagia	976|Bacteroidetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
TLS3_k127_2234287_3	761193.Runsl_3978	1.52e-117	388.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,47KCD@768503|Cytophagia	976|Bacteroidetes	M	PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal domain	menC	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
TLS3_k127_2234287_2	504728.K649_03245	4.169e-135	441.0	COG4638@1|root,COG4638@2|Bacteria	2|Bacteria	P	Rieske (2fe-2S)	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
TLS3_k127_2234287_4	1123278.KB893444_gene1666	2.421e-35	140.0	2C87P@1|root,32H7J@2|Bacteria,4NS7S@976|Bacteroidetes,47R39@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
TLS3_k127_2236200_0	395493.BegalDRAFT_0969	5.683e-55	213.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	ko:K11914	-	-	-	-	ko00000,ko02044,ko03000	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
TLS3_k127_2236200_1	1239962.C943_00868	5.165e-14	74.0	2AHBZ@1|root,317NP@2|Bacteria,4P8VE@976|Bacteroidetes,47WVY@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_223948_1	1279009.ADICEAN_02559	3.969e-227	711.0	COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,47JUJ@768503|Cytophagia	976|Bacteroidetes	G	Glycogen debranching enzyme, glucanotransferase domain	amyB	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Malt_amylase_C
TLS3_k127_223948_0	1123277.KB893174_gene5903	3.829e-265	840.0	COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_224975_0	1185876.BN8_00135	2.288e-321	1005.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47JBS@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
TLS3_k127_2252071_0	929556.Solca_3824	8.651e-80	269.0	COG0520@1|root,COG0520@2|Bacteria,4NJ4E@976|Bacteroidetes,1IQHG@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
TLS3_k127_2252071_1	929556.Solca_3822	1.497e-64	225.0	COG1522@1|root,COG1522@2|Bacteria,4NR3Z@976|Bacteroidetes,1ITIE@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
TLS3_k127_2252071_3	1121904.ARBP01000003_gene6370	2.336e-06	59.0	COG4743@1|root,COG4743@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1616
TLS3_k127_2252071_2	1239962.C943_03980	8.749e-35	136.0	COG1695@1|root,COG1695@2|Bacteria,4NQBA@976|Bacteroidetes,47RGZ@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_225370_1	700598.Niako_0984	1.634e-216	681.0	COG2235@1|root,COG2235@2|Bacteria,4NHKZ@976|Bacteroidetes,1IP21@117747|Sphingobacteriia	976|Bacteroidetes	E	Arginine deiminase	-	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
TLS3_k127_225370_3	700598.Niako_0983	2.525e-115	378.0	COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,1IQ05@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
TLS3_k127_225370_4	760192.Halhy_4337	8.771e-66	237.0	COG2267@1|root,COG2267@2|Bacteria,4NKKQ@976|Bacteroidetes	976|Bacteroidetes	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
TLS3_k127_225370_0	929562.Emtol_0851	1.807e-238	758.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47MUU@768503|Cytophagia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_225370_5	485918.Cpin_5750	7.372e-61	212.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,1ITGH@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_225370_6	1450525.JATV01000006_gene1044	4.04e-23	106.0	COG4704@1|root,COG4704@2|Bacteria,4NUS8@976|Bacteroidetes,1I45Z@117743|Flavobacteriia,2NX3W@237|Flavobacterium	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
TLS3_k127_225370_2	1123248.KB893340_gene2675	3.694e-124	409.0	COG0003@1|root,COG0003@2|Bacteria,4NNW8@976|Bacteroidetes	976|Bacteroidetes	D	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
TLS3_k127_226031_1	1237149.C900_04594	1.93e-240	756.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,47JXP@768503|Cytophagia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
TLS3_k127_226031_0	1237149.C900_04595	0.0	1061.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,47K6R@768503|Cytophagia	976|Bacteroidetes	M	Penicillin binding protein transpeptidase	pbpB	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
TLS3_k127_226031_2	1237149.C900_04596	7.932e-26	111.0	COG0457@1|root,COG0457@2|Bacteria,4NDV9@976|Bacteroidetes,47K0V@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeats	sprE	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
TLS3_k127_2262391_1	471854.Dfer_1970	7.457e-135	433.0	COG2133@1|root,COG2133@2|Bacteria,4NK4E@976|Bacteroidetes,47K5J@768503|Cytophagia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_2262391_0	616991.JPOO01000003_gene73	8.776e-225	702.0	COG0673@1|root,COG0673@2|Bacteria,4NGTW@976|Bacteroidetes,1I164@117743|Flavobacteriia,23IAD@178469|Arenibacter	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_2262391_2	1347342.BN863_21130	2.434e-13	72.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4NEZ5@976|Bacteroidetes,1HYTD@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,F5_F8_type_C,HEAT_2
TLS3_k127_2272717_1	1279009.ADICEAN_03863	2.756e-84	288.0	COG2203@1|root,COG2203@2|Bacteria,4P0X3@976|Bacteroidetes,47TEQ@768503|Cytophagia	976|Bacteroidetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
TLS3_k127_2272717_2	1279009.ADICEAN_03862	6.326e-52	190.0	COG0526@1|root,COG0526@2|Bacteria,4NPJ9@976|Bacteroidetes,47R36@768503|Cytophagia	976|Bacteroidetes	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_2
TLS3_k127_2272717_0	761193.Runsl_4441	1.076e-206	652.0	COG1649@1|root,COG1649@2|Bacteria,4NJ20@976|Bacteroidetes,47NNM@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL6
TLS3_k127_2278340_3	1237149.C900_01813	2.633e-70	250.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,47KIF@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
TLS3_k127_2278340_4	1237149.C900_01812	1.033e-65	231.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,47PCF@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
TLS3_k127_2278340_2	153721.MYP_4849	5.022e-87	292.0	COG0491@1|root,COG0491@2|Bacteria,4NE2Y@976|Bacteroidetes,47PA3@768503|Cytophagia	976|Bacteroidetes	P	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_2278340_1	1189612.A33Q_0663	7.976e-97	328.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,47JI9@768503|Cytophagia	976|Bacteroidetes	E	PFAM FAD dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
TLS3_k127_2278340_0	1237149.C900_01809	0.0	1166.0	COG0823@1|root,COG0823@2|Bacteria,4PNV1@976|Bacteroidetes,47YIP@768503|Cytophagia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_2286693_2	1048983.EL17_08510	3.317e-20	92.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,47PRE@768503|Cytophagia	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
TLS3_k127_2286693_1	1237149.C900_01575	3.201e-82	274.0	2C4H4@1|root,32CX0@2|Bacteria,4NRZ7@976|Bacteroidetes,47SG5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2290653_1	1124780.ANNU01000023_gene3243	3e-323	996.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,47JS9@768503|Cytophagia	976|Bacteroidetes	L	Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
TLS3_k127_2290653_0	1237149.C900_05830	0.0	1234.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,47JQZ@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
TLS3_k127_2290653_3	1237149.C900_00748	1.443e-43	168.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2
TLS3_k127_2290653_2	1185876.BN8_06214	2.853e-142	460.0	COG2706@1|root,COG2706@2|Bacteria,4NE87@976|Bacteroidetes,47KQB@768503|Cytophagia	976|Bacteroidetes	G	PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
TLS3_k127_229565_0	1237149.C900_05672	6.826e-169	533.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,47KP9@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
TLS3_k127_229565_1	1237149.C900_00266	1.976e-168	541.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,47K9B@768503|Cytophagia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
TLS3_k127_2314516_3	1313301.AUGC01000008_gene515	8.317e-37	144.0	2EE99@1|root,3383P@2|Bacteria,4NWQD@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
TLS3_k127_2314516_2	1121904.ARBP01000028_gene1645	1.664e-98	330.0	COG1090@1|root,COG1090@2|Bacteria,4NINM@976|Bacteroidetes,47KA1@768503|Cytophagia	976|Bacteroidetes	S	PFAM NAD dependent epimerase dehydratase family	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
TLS3_k127_2314516_0	641524.ADICYQ_5525	1.545e-147	478.0	COG2152@1|root,COG2152@2|Bacteria,4NG7B@976|Bacteroidetes,47MHY@768503|Cytophagia	976|Bacteroidetes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	3.2.1.197	ko:K21065	-	-	R11544	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
TLS3_k127_2314516_1	1124780.ANNU01000006_gene2951	3.569e-110	362.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,47M0E@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
TLS3_k127_2320975_0	1123248.KB893319_gene4085	1.355e-70	240.0	COG0784@1|root,COG0784@2|Bacteria,4P519@976|Bacteroidetes	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_2320975_3	1239962.C943_00989	1.519e-26	117.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	MA20_20735	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_2320975_1	643867.Ftrac_1500	2.627e-45	167.0	COG5001@1|root,COG5001@2|Bacteria,4PKIC@976|Bacteroidetes,47YDG@768503|Cytophagia	976|Bacteroidetes	T	Sensors of blue-light using FAD	-	-	-	-	-	-	-	-	-	-	-	-	BLUF
TLS3_k127_2320975_2	761193.Runsl_1039	1.187e-37	143.0	COG0784@1|root,COG0784@2|Bacteria,4NR3J@976|Bacteroidetes,47QYW@768503|Cytophagia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_2321825_4	1237149.C900_05301	4.112e-20	91.0	COG4877@1|root,COG4877@2|Bacteria,4NXSU@976|Bacteroidetes,47T6F@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
TLS3_k127_2321825_2	1237149.C900_05303	5.447e-129	417.0	COG0330@1|root,COG0330@2|Bacteria,4NEBV@976|Bacteroidetes,47JW8@768503|Cytophagia	976|Bacteroidetes	O	membrane protease	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TLS3_k127_2321825_3	643867.Ftrac_0458	2.643e-96	324.0	COG3781@1|root,COG3781@2|Bacteria,4NEB1@976|Bacteroidetes,47N85@768503|Cytophagia	976|Bacteroidetes	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
TLS3_k127_2321825_1	1237149.C900_00643	4.31e-158	506.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,47K3D@768503|Cytophagia	976|Bacteroidetes	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
TLS3_k127_2321825_0	1237149.C900_00644	5.706e-209	657.0	COG2937@1|root,COG2937@2|Bacteria,4NK5H@976|Bacteroidetes,47M20@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TLS3_k127_2324099_2	867900.Celly_0689	1.605e-37	147.0	2C852@1|root,32YB2@2|Bacteria,4NM63@976|Bacteroidetes,1I1C4@117743|Flavobacteriia,1F95N@104264|Cellulophaga	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
TLS3_k127_2324099_1	376686.Fjoh_3349	8.873e-145	468.0	28IAE@1|root,2Z8D0@2|Bacteria,4NFWC@976|Bacteroidetes,1I0D2@117743|Flavobacteriia,2NTN6@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2324099_0	1347342.BN863_11570	0.0	1367.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,1HZSK@117743|Flavobacteriia	976|Bacteroidetes	P	sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
TLS3_k127_2330716_0	1185876.BN8_05127	1e-294	912.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47KGQ@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
TLS3_k127_2335642_0	1237149.C900_05488	0.0	1022.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,47MDC@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
TLS3_k127_2335854_2	1123277.KB893195_gene5625	1.3e-18	91.0	COG2207@1|root,COG2207@2|Bacteria,4NHYH@976|Bacteroidetes,47VC8@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_2335854_0	886377.Murru_1827	4.111e-207	648.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1HYHK@117743|Flavobacteriia	976|Bacteroidetes	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
TLS3_k127_2335854_1	1120966.AUBU01000003_gene1407	4.573e-188	593.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,47KCH@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
TLS3_k127_2335854_3	926556.Echvi_2481	2.32e-07	53.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes,47KTT@768503|Cytophagia	976|Bacteroidetes	Q	fumarylacetoacetate (FAA) hydrolase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
TLS3_k127_2341473_7	869213.JCM21142_41972	4.508e-23	101.0	COG3608@1|root,COG3608@2|Bacteria,4NE8S@976|Bacteroidetes,47KAM@768503|Cytophagia	976|Bacteroidetes	S	PFAM Succinylglutamate desuccinylase Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
TLS3_k127_2341473_6	1304885.AUEY01000017_gene3764	1.652e-32	133.0	COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,43AE6@68525|delta/epsilon subdivisions,2X6A8@28221|Deltaproteobacteria,2MPXN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
TLS3_k127_2341473_5	1237149.C900_02720	1.829e-43	164.0	COG2825@1|root,COG2825@2|Bacteria,4NQHJ@976|Bacteroidetes,47QWE@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane protein (OmpH-like)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TLS3_k127_2341473_3	509635.N824_26605	8.11e-60	216.0	COG3823@1|root,COG3823@2|Bacteria,4P2CR@976|Bacteroidetes,1IXIA@117747|Sphingobacteriia	976|Bacteroidetes	O	Glutamine cyclotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2
TLS3_k127_2341473_0	1123248.KB893314_gene3542	6.145e-300	927.0	COG2303@1|root,COG2303@2|Bacteria,4NHJT@976|Bacteroidetes,1IRDW@117747|Sphingobacteriia	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
TLS3_k127_2341473_2	862908.BMS_1959	1.392e-68	243.0	COG3221@1|root,COG3221@2|Bacteria,1MXD8@1224|Proteobacteria,42VZ4@68525|delta/epsilon subdivisions,2MSSI@213481|Bdellovibrionales,2WRDI@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
TLS3_k127_2341473_1	1239962.C943_01303	1.426e-203	643.0	COG5361@1|root,COG5361@2|Bacteria,4NKSK@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
TLS3_k127_2341473_4	1239962.C943_01304	3.615e-54	192.0	COG5361@1|root,COG5361@2|Bacteria,4NKSK@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
TLS3_k127_2343261_4	388413.ALPR1_16848	7.822e-06	48.0	COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,47PSE@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
TLS3_k127_2343261_1	1492738.FEM21_01740	5.845e-97	322.0	COG3828@1|root,COG3828@2|Bacteria,4NDVK@976|Bacteroidetes,1HZM2@117743|Flavobacteriia,2NVKF@237|Flavobacterium	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	DUF1080,ThuA
TLS3_k127_2343261_0	1189612.A33Q_0972	7.929e-132	424.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,47JN8@768503|Cytophagia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
TLS3_k127_2343261_2	1237149.C900_05671	9.537e-55	199.0	2CYF8@1|root,32T43@2|Bacteria,4NUAU@976|Bacteroidetes,47RBY@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2343261_3	1237149.C900_05672	3.292e-53	188.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,47KP9@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
TLS3_k127_2343751_3	1237149.C900_01219	2.185e-39	147.0	COG4932@1|root,COG5644@1|root,COG4932@2|Bacteria,COG5644@2|Bacteria,4NN56@976|Bacteroidetes,47Q8D@768503|Cytophagia	976|Bacteroidetes	M	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS
TLS3_k127_2343751_2	643867.Ftrac_3145	4.521e-102	341.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,47KE6@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_2343751_0	1237149.C900_01447	1.619e-318	988.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,47KMU@768503|Cytophagia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
TLS3_k127_2343751_1	153721.MYP_2242	3.813e-191	599.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,47K1X@768503|Cytophagia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
TLS3_k127_2346353_0	1121904.ARBP01000068_gene5318	4.147e-92	311.0	COG4251@1|root,COG4251@2|Bacteria,4NHEM@976|Bacteroidetes,47QEB@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
TLS3_k127_2346353_2	682795.AciX8_0964	2.97e-12	79.0	COG1434@1|root,COG1434@2|Bacteria,3Y6H5@57723|Acidobacteria,2JK81@204432|Acidobacteriia	204432|Acidobacteriia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
TLS3_k127_2346353_4	1380384.JADN01000003_gene838	0.0009684	46.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
TLS3_k127_2346353_3	1094466.KQS_05085	1.485e-06	52.0	2DH84@1|root,2ZYR5@2|Bacteria,4PDPQ@976|Bacteroidetes,1IE3Y@117743|Flavobacteriia,2NZTJ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2346353_1	929556.Solca_3628	2.506e-76	259.0	COG0666@1|root,COG0666@2|Bacteria,4NVG2@976|Bacteroidetes,1IZQA@117747|Sphingobacteriia	976|Bacteroidetes	S	ankyrin repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2347659_3	1279009.ADICEAN_02472	2.789e-162	519.0	COG0673@1|root,COG0673@2|Bacteria,4NFMS@976|Bacteroidetes,47K95@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_2347659_5	1380394.JADL01000003_gene5084	4.467e-97	330.0	COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2VG2H@28211|Alphaproteobacteria,2JZP7@204441|Rhodospirillales	204441|Rhodospirillales	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
TLS3_k127_2347659_6	761193.Runsl_3437	3.045e-94	316.0	COG0596@1|root,COG0596@2|Bacteria,4NFIB@976|Bacteroidetes,47QW1@768503|Cytophagia	976|Bacteroidetes	S	Alpha/beta hydrolase family	rsbQ	-	-	ko:K19707	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
TLS3_k127_2347659_2	1227739.Hsw_2788	5.587e-169	542.0	COG0001@1|root,COG0001@2|Bacteria,4NK3F@976|Bacteroidetes,47NWU@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Amidohydro_2,Aminotran_3
TLS3_k127_2347659_1	272134.KB731324_gene1965	6.09e-176	561.0	COG4310@1|root,COG4310@2|Bacteria,1G39N@1117|Cyanobacteria,1H9B5@1150|Oscillatoriales	1117|Cyanobacteria	S	winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	DUF2172,DUF4910,HTH_47
TLS3_k127_2347659_8	1392498.JQLH01000001_gene1777	4.181e-21	98.0	2C3W3@1|root,33ZIZ@2|Bacteria,4P4U0@976|Bacteroidetes,1I9GJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2347659_7	1121957.ATVL01000012_gene848	2.887e-80	276.0	COG0363@1|root,COG0363@2|Bacteria,4NGB9@976|Bacteroidetes,47KK9@768503|Cytophagia	976|Bacteroidetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
TLS3_k127_2347659_0	1123248.KB893314_gene3293	3.564e-249	777.0	COG0364@1|root,COG0364@2|Bacteria,4NE59@976|Bacteroidetes,1IQZ7@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
TLS3_k127_2347659_4	714943.Mucpa_6661	1.25e-131	425.0	COG0362@1|root,COG0362@2|Bacteria,4NG05@976|Bacteroidetes,1IPZC@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
TLS3_k127_2368404_2	1121904.ARBP01000008_gene3332	3.681e-25	105.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_2368404_0	1121904.ARBP01000030_gene1933	3.389e-289	912.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_2368404_1	1121011.AUCB01000005_gene2320	3.419e-141	455.0	COG1082@1|root,COG1082@2|Bacteria,4NKFY@976|Bacteroidetes,1I3V7@117743|Flavobacteriia,23HPC@178469|Arenibacter	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_2368404_3	1122603.ATVI01000005_gene3498	4.764e-09	67.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SZ6C@1236|Gammaproteobacteria,1XCCV@135614|Xanthomonadales	1236|Gammaproteobacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_19,TPR_2,TPR_8
TLS3_k127_2368726_0	643867.Ftrac_0981	1.681e-145	466.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,47JJD@768503|Cytophagia	976|Bacteroidetes	G	PFAM Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
TLS3_k127_2368726_1	1237149.C900_00612	3.917e-140	459.0	COG2304@1|root,COG2304@2|Bacteria,4NJF1@976|Bacteroidetes,47MRQ@768503|Cytophagia	976|Bacteroidetes	S	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
TLS3_k127_2368726_2	1122621.ATZA01000002_gene1618	2.786e-08	55.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,1IR3A@117747|Sphingobacteriia	976|Bacteroidetes	G	Transketolase	dxs	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
TLS3_k127_2372582_0	1131812.JQMS01000001_gene2046	4.829e-150	488.0	COG0443@1|root,COG0443@2|Bacteria,4NJFK@976|Bacteroidetes,1HYW7@117743|Flavobacteriia,2NYTX@237|Flavobacterium	976|Bacteroidetes	O	Hsp70 protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
TLS3_k127_2372582_2	1469557.JSWF01000039_gene3068	6.961e-21	97.0	2DR79@1|root,33AIG@2|Bacteria,4NYDE@976|Bacteroidetes,1I6BF@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2372582_1	1121904.ARBP01000001_gene5779	7.812e-31	123.0	COG3682@1|root,COG3682@2|Bacteria,4NNVM@976|Bacteroidetes,47Q5Z@768503|Cytophagia	976|Bacteroidetes	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
TLS3_k127_2374550_5	641107.CDLVIII_1053	3.697e-06	53.0	COG5658@1|root,COG5658@2|Bacteria,1VB6E@1239|Firmicutes,24MSY@186801|Clostridia,36N1V@31979|Clostridiaceae	186801|Clostridia	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
TLS3_k127_2374550_2	388413.ALPR1_16394	8.571e-69	239.0	COG4341@1|root,COG4341@2|Bacteria,4NPMZ@976|Bacteroidetes,47PFD@768503|Cytophagia	976|Bacteroidetes	S	HD domain	-	-	1.13.11.78	ko:K21196	ko00440,map00440	-	R10722	RC03261	ko00000,ko00001,ko01000	-	-	-	HD
TLS3_k127_2374550_3	525373.HMPREF0766_11330	3.706e-58	209.0	COG0546@1|root,COG0546@2|Bacteria,4NMEX@976|Bacteroidetes,1IS6P@117747|Sphingobacteriia	976|Bacteroidetes	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
TLS3_k127_2374550_4	1185876.BN8_06591	2.99e-08	62.0	2E9CR@1|root,333KC@2|Bacteria,4NWPT@976|Bacteroidetes,47SKK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2374550_0	1267211.KI669560_gene349	1.364e-133	439.0	2C31A@1|root,2Z7UP@2|Bacteria,4NECU@976|Bacteroidetes,1IQU7@117747|Sphingobacteriia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2374550_1	1239962.C943_03724	9.61e-82	280.0	COG1387@1|root,COG1387@2|Bacteria,4NIJU@976|Bacteroidetes,47Q20@768503|Cytophagia	976|Bacteroidetes	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
TLS3_k127_2386388_1	929556.Solca_1158	7.039e-123	395.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,4NGX5@976|Bacteroidetes,1IRAD@117747|Sphingobacteriia	976|Bacteroidetes	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
TLS3_k127_2386388_0	929556.Solca_1157	4.516e-178	565.0	COG0282@1|root,COG0282@2|Bacteria,4NFI0@976|Bacteroidetes,1IPB9@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
TLS3_k127_2386388_2	1121897.AUGO01000007_gene443	6.853e-61	211.0	2CUMY@1|root,32SVM@2|Bacteria,4NTF0@976|Bacteroidetes,1I3KN@117743|Flavobacteriia,2NZXB@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_2387253_3	1189612.A33Q_0048	3.305e-144	466.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,47JVV@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
TLS3_k127_2387253_8	1237149.C900_04166	5.677e-50	184.0	2FKBG@1|root,34BYZ@2|Bacteria,4P6N9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2387253_2	866536.Belba_2741	1.227e-152	485.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,47JZ7@768503|Cytophagia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS3_k127_2387253_1	1124780.ANNU01000025_gene3400	3.204e-153	495.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,47K0F@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
TLS3_k127_2387253_6	1237149.C900_03416	2.06e-82	279.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,47JY6@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
TLS3_k127_2387253_4	1237149.C900_02545	5.936e-140	449.0	COG2908@1|root,COG2908@2|Bacteria,4NFD8@976|Bacteroidetes,47MNV@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
TLS3_k127_2387253_5	1237149.C900_02544	3.129e-122	400.0	COG1819@1|root,COG1819@2|Bacteria,4NFYF@976|Bacteroidetes,47XWY@768503|Cytophagia	976|Bacteroidetes	CG	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_3
TLS3_k127_2387253_7	1237149.C900_02543	8.128e-69	241.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,47MJ5@768503|Cytophagia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07657,ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_2387253_0	1237149.C900_05453	9.816e-166	536.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,47MZQ@768503|Cytophagia	976|Bacteroidetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
TLS3_k127_2388767_0	1237149.C900_04086	5.046e-129	426.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JYF@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_2388767_2	1150600.ADIARSV_3688	6.355e-07	52.0	2EK7X@1|root,33DY9@2|Bacteria,4NYAQ@976|Bacteroidetes,1IUER@117747|Sphingobacteriia	976|Bacteroidetes	S	Virus attachment protein p12 family	-	-	-	-	-	-	-	-	-	-	-	-	P12
TLS3_k127_2388767_1	313606.M23134_03596	3.749e-52	185.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,47K59@768503|Cytophagia	976|Bacteroidetes	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
TLS3_k127_2393704_3	1469557.JSWF01000032_gene3154	5.648e-06	56.0	2E3AK@1|root,32YA3@2|Bacteria,4NUYM@976|Bacteroidetes,1I4YQ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2393704_0	1237149.C900_00003	5.536e-150	477.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,47JCR@768503|Cytophagia	976|Bacteroidetes	S	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_2393704_2	1123057.P872_08550	1.543e-77	267.0	COG1752@1|root,COG1752@2|Bacteria,4NERH@976|Bacteroidetes,47JZ5@768503|Cytophagia	976|Bacteroidetes	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
TLS3_k127_2393704_1	1237149.C900_00005	1.295e-120	390.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,47K5S@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
TLS3_k127_2395792_10	525257.HMPREF0204_13528	7.28e-24	104.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1HXF3@117743|Flavobacteriia,3ZR2E@59732|Chryseobacterium	976|Bacteroidetes	S	Transporter associated domain	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
TLS3_k127_2395792_5	1237149.C900_04890	1.453e-117	387.0	COG0598@1|root,COG0598@2|Bacteria,4NG3C@976|Bacteroidetes,47JWS@768503|Cytophagia	976|Bacteroidetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
TLS3_k127_2395792_3	1237149.C900_04887	1.297e-157	502.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,47KFN@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
TLS3_k127_2395792_2	1237149.C900_04882	7.528e-176	563.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,47JHV@768503|Cytophagia	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
TLS3_k127_2395792_4	1124780.ANNU01000024_gene3133	7.763e-121	395.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,47KF6@768503|Cytophagia	976|Bacteroidetes	V	TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_2395792_6	1454007.JAUG01000016_gene1722	1.744e-77	267.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,1IRI4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
TLS3_k127_2395792_0	1237149.C900_04875	1.28e-203	649.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,47JZF@768503|Cytophagia	976|Bacteroidetes	N	ABC transporter substrate-binding component GldG	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
TLS3_k127_2395792_9	1237149.C900_04874	2.949e-42	167.0	2E7J5@1|root,3321E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
TLS3_k127_2395792_1	1237149.C900_04873	3.24e-195	613.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,47M1J@768503|Cytophagia	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
TLS3_k127_2395792_7	1237149.C900_04374	7.632e-66	228.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,47QNZ@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM phosphoesterase, MJ0936 family	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
TLS3_k127_2404261_0	760192.Halhy_4014	2.011e-212	664.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,1IPNZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
TLS3_k127_2404261_2	760192.Halhy_4029	7.073e-17	80.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,1IU87@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
TLS3_k127_2404261_1	760192.Halhy_2765	3.446e-23	104.0	COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,1IT9C@117747|Sphingobacteriia	976|Bacteroidetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
TLS3_k127_2429846_0	1121373.KB903631_gene607	1.844e-58	215.0	COG2340@1|root,COG2340@2|Bacteria,4PC4Z@976|Bacteroidetes,47WU2@768503|Cytophagia	976|Bacteroidetes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
TLS3_k127_2429846_1	694427.Palpr_2287	2.427e-24	104.0	COG2827@1|root,COG2827@2|Bacteria,4NUN3@976|Bacteroidetes	976|Bacteroidetes	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
TLS3_k127_2429846_2	748280.NH8B_2423	4.181e-20	100.0	2E631@1|root,330S3@2|Bacteria,1NJ41@1224|Proteobacteria,2W4BQ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2431708_8	1237149.C900_01027	5.577e-08	54.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,47KWQ@768503|Cytophagia	976|Bacteroidetes	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
TLS3_k127_2431708_1	1237149.C900_01026	3.546e-192	602.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,47JQ4@768503|Cytophagia	976|Bacteroidetes	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
TLS3_k127_2431708_0	1237149.C900_01025	3.924e-228	715.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,47JQT@768503|Cytophagia	976|Bacteroidetes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
TLS3_k127_2431708_3	1124780.ANNU01000043_gene329	2.578e-102	340.0	COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,47JPF@768503|Cytophagia	976|Bacteroidetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	yafV	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
TLS3_k127_2431708_2	485918.Cpin_0778	4.296e-140	454.0	COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,1IP0R@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_2431708_4	1237149.C900_01739	2.385e-75	256.0	COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,47JIG@768503|Cytophagia	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
TLS3_k127_2431708_7	471854.Dfer_4051	6.439e-43	163.0	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,47QCM@768503|Cytophagia	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
TLS3_k127_2431708_6	761193.Runsl_1328	4.662e-44	166.0	COG0262@1|root,COG0262@2|Bacteria,4NJIQ@976|Bacteroidetes,47PHT@768503|Cytophagia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
TLS3_k127_2431708_5	1237149.C900_01741	1.504e-73	252.0	COG2846@1|root,COG2846@2|Bacteria,4NPQ7@976|Bacteroidetes,47PY2@768503|Cytophagia	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin
TLS3_k127_2432267_4	1237149.C900_04716	1.312e-100	336.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,47JUC@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
TLS3_k127_2432267_3	1124780.ANNU01000028_gene992	5.028e-130	430.0	COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,47MQE@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
TLS3_k127_2432267_1	1124780.ANNU01000028_gene994	2.872e-146	470.0	COG1208@1|root,COG1208@2|Bacteria,4NE97@976|Bacteroidetes,47ND5@768503|Cytophagia	976|Bacteroidetes	JM	Nucleotidyl transferase	rffH	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
TLS3_k127_2432267_0	1237149.C900_04713	4.95e-164	534.0	COG0457@1|root,COG0457@2|Bacteria,4NDVW@976|Bacteroidetes,47KE1@768503|Cytophagia	976|Bacteroidetes	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
TLS3_k127_2432267_2	1237149.C900_04711	2.461e-132	434.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,47JWJ@768503|Cytophagia	976|Bacteroidetes	D	Peptidase, M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_2478296_0	1121904.ARBP01000004_gene1059	4.137e-177	580.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_2478296_1	1267211.KI669560_gene2472	4.033e-121	398.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1INM5@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
TLS3_k127_2478296_2	929556.Solca_0259	2.832e-29	120.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IRGG@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_248034_2	1237149.C900_02785	2.127e-136	440.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,47KBG@768503|Cytophagia	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
TLS3_k127_248034_5	1237149.C900_02786	1.403e-75	263.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,47PXV@768503|Cytophagia	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
TLS3_k127_248034_4	1237149.C900_02789	2.241e-97	324.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,47MAX@768503|Cytophagia	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
TLS3_k127_248034_3	1230343.CANP01000042_gene3124	1.59e-113	378.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1RYK4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_248034_1	1048983.EL17_13420	3.777e-161	512.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,47K34@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
TLS3_k127_248034_6	1124780.ANNU01000030_gene1140	7.905e-62	237.0	COG0642@1|root,COG0642@2|Bacteria,4PN6C@976|Bacteroidetes,47YKA@768503|Cytophagia	976|Bacteroidetes	T	7TMR-DISM extracellular 2	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c
TLS3_k127_248034_0	1124780.ANNU01000005_gene2472	7.312e-181	570.0	COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,47M82@768503|Cytophagia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
TLS3_k127_248034_7	1237149.C900_02765	1.811e-45	169.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,47N34@768503|Cytophagia	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
TLS3_k127_248298_3	1237149.C900_03712	2.472e-120	407.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NTSQ@976|Bacteroidetes	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,TPR_8
TLS3_k127_248298_1	1250232.JQNJ01000001_gene473	5.622e-168	539.0	COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,1HZG2@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_248298_2	153721.MYP_2562	6.041e-135	437.0	COG1077@1|root,COG1077@2|Bacteria,4P0IR@976|Bacteroidetes,47TJZ@768503|Cytophagia	976|Bacteroidetes	D	MreB/Mbl protein	-	-	-	-	-	-	-	-	-	-	-	-	MreB_Mbl
TLS3_k127_248298_4	1237149.C900_03604	9.867e-72	252.0	COG2067@1|root,COG2067@2|Bacteria,4NVCH@976|Bacteroidetes,47SCX@768503|Cytophagia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_248298_0	1237149.C900_03605	1.378e-220	688.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,47JZU@768503|Cytophagia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
TLS3_k127_248298_5	509635.N824_18985	2.114e-16	79.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1IPBQ@117747|Sphingobacteriia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
TLS3_k127_2484367_3	929713.NIASO_05040	4.936e-112	368.0	COG4585@1|root,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,1INUH@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
TLS3_k127_2484367_5	929713.NIASO_05035	3.305e-78	266.0	COG2197@1|root,COG2197@2|Bacteria,4NMTW@976|Bacteroidetes,1IVY0@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_2484367_0	1123277.KB893172_gene761	9.938e-171	545.0	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,47M6K@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_2484367_4	643867.Ftrac_0613	1.505e-102	353.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HATPase_c,HisKA,PAS_9,Response_reg
TLS3_k127_2484367_1	1089547.KB913013_gene3972	2.273e-134	438.0	COG3325@1|root,COG3325@2|Bacteria,4NGAZ@976|Bacteroidetes,47JXX@768503|Cytophagia	976|Bacteroidetes	G	Glyco_18	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
TLS3_k127_2484367_6	313606.M23134_05213	2.985e-54	203.0	arCOG09742@1|root,2ZBGR@2|Bacteria,4NRNU@976|Bacteroidetes,47V53@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2484367_2	153721.MYP_3091	1.03e-126	416.0	COG2304@1|root,COG2304@2|Bacteria,4NEGD@976|Bacteroidetes	976|Bacteroidetes	P	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
TLS3_k127_2502847_0	1089547.KB913013_gene3787	7.389e-290	902.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,47Y2J@768503|Cytophagia	976|Bacteroidetes	H	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_2502847_1	1185876.BN8_04289	1.903e-193	615.0	COG4198@1|root,COG4198@2|Bacteria,4NEQC@976|Bacteroidetes,47JPV@768503|Cytophagia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_2
TLS3_k127_2502847_6	1185876.BN8_04290	1.065e-28	124.0	29WUX@1|root,30IGE@2|Bacteria,4NNWZ@976|Bacteroidetes,47PS9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2502847_2	1121859.KB890750_gene564	2.054e-130	427.0	COG0079@1|root,COG0079@2|Bacteria,4NEW8@976|Bacteroidetes,47M27@768503|Cytophagia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_2502847_3	1123057.P872_12025	1.918e-89	307.0	COG0679@1|root,COG0679@2|Bacteria,4NGI3@976|Bacteroidetes,47MZJ@768503|Cytophagia	976|Bacteroidetes	S	Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	-
TLS3_k127_2502847_4	1267535.KB906767_gene4875	1.101e-65	228.0	COG2080@1|root,COG2080@2|Bacteria,3Y4U1@57723|Acidobacteria,2JMWP@204432|Acidobacteriia	204432|Acidobacteriia	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
TLS3_k127_2502847_5	945713.IALB_2573	4.047e-41	158.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
TLS3_k127_2514695_0	525897.Dbac_2188	9.192e-204	652.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria,2M8AX@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
TLS3_k127_2515293_2	760192.Halhy_4100	1.044e-35	137.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INWS@117747|Sphingobacteriia	976|Bacteroidetes	V	InterPro IPR003838	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_2515293_1	485918.Cpin_4240	8.496e-123	397.0	COG3693@1|root,COG3693@2|Bacteria,4NE5Z@976|Bacteroidetes,1IRC2@117747|Sphingobacteriia	976|Bacteroidetes	G	SMART glycoside hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Esterase,Glyco_hydro_10
TLS3_k127_2515293_3	1123248.KB893335_gene2863	1.59e-24	106.0	COG3693@1|root,COG3693@2|Bacteria,4NE5Z@976|Bacteroidetes,1IV43@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Esterase,Glyco_hydro_10
TLS3_k127_2515293_0	655815.ZPR_3025	5.091e-182	580.0	COG1506@1|root,COG1506@2|Bacteria,4PKQ3@976|Bacteroidetes,1IK7Y@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_2517226_4	1237149.C900_01983	3.158e-21	110.0	COG3291@1|root,COG4625@1|root,COG3291@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	rhgB	-	4.2.2.23	ko:K07004,ko:K18195	-	-	-	-	ko00000,ko01000	-	PL4	-	CBM-like,CHU_C,He_PIG,PKD,RhgB_N,fn3_3
TLS3_k127_2517226_1	493475.GARC_2123	6.699e-56	222.0	COG2911@1|root,COG4935@1|root,COG2911@2|Bacteria,COG4935@2|Bacteria,1NJV7@1224|Proteobacteria,1RN7Q@1236|Gammaproteobacteria,465ZC@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_4
TLS3_k127_2517226_2	1237149.C900_05678	4.508e-39	147.0	COG0526@1|root,COG0526@2|Bacteria,4PKQI@976|Bacteroidetes,47XZ0@768503|Cytophagia	976|Bacteroidetes	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
TLS3_k127_2517226_0	1121870.AUAA01000035_gene111	4.308e-58	205.0	COG1764@1|root,COG1764@2|Bacteria,4NNF7@976|Bacteroidetes,1I1XV@117743|Flavobacteriia,3HIF1@358033|Chryseobacterium	976|Bacteroidetes	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
TLS3_k127_2517226_3	694427.Palpr_2541	1.096e-38	147.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,2FV0P@200643|Bacteroidia,22YT4@171551|Porphyromonadaceae	976|Bacteroidetes	P	Sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS3_k127_2517226_5	643867.Ftrac_2337	4.804e-21	94.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,47S4A@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
TLS3_k127_254531_8	1408433.JHXV01000005_gene2462	1.946e-24	104.0	2E5WH@1|root,30K07@2|Bacteria,4P5HE@976|Bacteroidetes,1ICRB@117743|Flavobacteriia,2PBVH@246874|Cryomorphaceae	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
TLS3_k127_254531_9	1305737.JAFX01000001_gene1070	6.703e-15	78.0	COG2827@1|root,COG2827@2|Bacteria,4NV6N@976|Bacteroidetes,47X40@768503|Cytophagia	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
TLS3_k127_254531_5	1237149.C900_04232	1.294e-48	179.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,47R94@768503|Cytophagia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_254531_1	1237149.C900_04233	5.209e-174	563.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,47JCU@768503|Cytophagia	976|Bacteroidetes	S	Permease YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
TLS3_k127_254531_7	1237149.C900_04234	7.104e-35	135.0	COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,47R7H@768503|Cytophagia	976|Bacteroidetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
TLS3_k127_254531_0	1237149.C900_04235	0.0	1052.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,47KTE@768503|Cytophagia	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
TLS3_k127_254531_2	1237149.C900_04236	6.985e-169	532.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,47JZ7@768503|Cytophagia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS3_k127_254531_3	1237149.C900_04237	1.961e-158	505.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,47JQX@768503|Cytophagia	976|Bacteroidetes	C	Thioredoxin reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_254531_4	1124780.ANNU01000002_gene1617	5.106e-98	327.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,47K51@768503|Cytophagia	976|Bacteroidetes	S	PFAM GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
TLS3_k127_254531_6	1237149.C900_02541	6.255e-35	135.0	COG0259@1|root,COG0259@2|Bacteria,4NFH7@976|Bacteroidetes,47P7A@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
TLS3_k127_254623_0	1189612.A33Q_3407	0.0	1298.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47JJ5@768503|Cytophagia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
TLS3_k127_2548407_1	269798.CHU_1434	1.952e-108	354.0	COG1410@1|root,COG1410@2|Bacteria,4PKI8@976|Bacteroidetes,47XZT@768503|Cytophagia	976|Bacteroidetes	E	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,DUF559,Met_synt_B12,Pterin_bind
TLS3_k127_2548407_0	1237149.C900_00621	5.849e-170	539.0	COG0646@1|root,COG0646@2|Bacteria,4NFRF@976|Bacteroidetes,47KPH@768503|Cytophagia	976|Bacteroidetes	E	Homocysteine S-methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
TLS3_k127_2548407_2	1237149.C900_00622	8.395e-84	283.0	COG0248@1|root,COG0248@2|Bacteria,4NEI0@976|Bacteroidetes,47KHJ@768503|Cytophagia	976|Bacteroidetes	FP	PFAM Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
TLS3_k127_257098_2	1121481.AUAS01000005_gene1880	6.283e-34	134.0	COG0656@1|root,COG0656@2|Bacteria,4NK47@976|Bacteroidetes,47MZY@768503|Cytophagia	976|Bacteroidetes	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_257098_1	1237149.C900_00659	2.031e-137	450.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
TLS3_k127_257098_0	1237149.C900_04089	5.587e-211	663.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia	976|Bacteroidetes	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_257098_3	1123248.KB893338_gene2306	1.888e-21	97.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IRGG@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_2584112_0	700598.Niako_1609	9.567e-59	206.0	COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes,1IT1Y@117747|Sphingobacteriia	976|Bacteroidetes	O	TIGRFAM Peroxiredoxin, osmotically inducible protein C, subgroup	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
TLS3_k127_2584112_3	1122605.KB893647_gene353	2.828e-31	126.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,1IYVW@117747|Sphingobacteriia	976|Bacteroidetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
TLS3_k127_2584112_2	509635.N824_00240	2.192e-34	139.0	COG1595@1|root,COG1595@2|Bacteria,4NSXH@976|Bacteroidetes	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_2584112_1	1123277.KB893176_gene3718	5.035e-55	206.0	COG3712@1|root,COG3712@2|Bacteria,4NSEH@976|Bacteroidetes,47RNC@768503|Cytophagia	976|Bacteroidetes	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
TLS3_k127_2587945_2	641524.ADICYQ_1281	2.803e-09	59.0	COG0709@1|root,COG0709@2|Bacteria,4NI4R@976|Bacteroidetes,47JJA@768503|Cytophagia	976|Bacteroidetes	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
TLS3_k127_2587945_0	1123248.KB893370_gene5077	5.003e-269	846.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,4NGJ4@976|Bacteroidetes,1IVIN@117747|Sphingobacteriia	976|Bacteroidetes	G	Trehalose-phosphatase	-	-	2.4.1.15,3.1.3.12	ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
TLS3_k127_2587945_1	313606.M23134_00592	1.014e-171	549.0	COG3387@1|root,COG3387@2|Bacteria,4NEE6@976|Bacteroidetes,47MRU@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 15	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glyco_hydro_15
TLS3_k127_258966_2	1237149.C900_03442	3.947e-116	395.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,47KXU@768503|Cytophagia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,fn3_3
TLS3_k127_258966_3	1237149.C900_03441	2.538e-79	274.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,47K52@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
TLS3_k127_258966_0	1124780.ANNU01000015_gene1981	8.712e-313	966.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,47JCG@768503|Cytophagia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
TLS3_k127_258966_5	761193.Runsl_1773	9.791e-48	174.0	COG0319@1|root,COG0319@2|Bacteria,4NS93@976|Bacteroidetes,47Q9Q@768503|Cytophagia	976|Bacteroidetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	-	-	-	-	-	-	-	-	-	UPF0054
TLS3_k127_258966_4	1237149.C900_03438	5.584e-66	226.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,47QUX@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
TLS3_k127_258966_1	1237149.C900_03437	3.25e-118	391.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,47NNE@768503|Cytophagia	976|Bacteroidetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
TLS3_k127_2592927_0	504472.Slin_2981	3.694e-275	867.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
TLS3_k127_2592927_1	1123248.KB893334_gene2753	5.419e-105	346.0	COG0596@1|root,COG0596@2|Bacteria,4NN9S@976|Bacteroidetes	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
TLS3_k127_2592927_2	1123248.KB893334_gene2754	1.722e-97	326.0	COG2207@1|root,COG2207@2|Bacteria,4NJUT@976|Bacteroidetes,1ITWE@117747|Sphingobacteriia	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_2592927_5	485913.Krac_4433	5.184e-12	71.0	COG0251@1|root,COG0251@2|Bacteria,2G9SU@200795|Chloroflexi	2|Bacteria	J	translation initiation inhibitor yjgF family	MA20_36215	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
TLS3_k127_2592927_3	929556.Solca_0266	1.781e-91	331.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IW4Z@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_2592927_4	1121904.ARBP01000005_gene4629	1.255e-67	249.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_2603034_1	1279009.ADICEAN_01664	5.795e-13	76.0	COG3291@1|root,COG3291@2|Bacteria,4NJW2@976|Bacteroidetes,47K98@768503|Cytophagia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_2603034_0	1237149.C900_04377	8.549e-178	563.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,47MP5@768503|Cytophagia	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
TLS3_k127_261531_2	269798.CHU_1616	2.93e-59	211.0	COG1595@1|root,COG1595@2|Bacteria,4NN4K@976|Bacteroidetes,47QDX@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	fecI	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS3_k127_261531_0	1288963.ADIS_2103	9.416e-149	485.0	COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,47JJT@768503|Cytophagia	976|Bacteroidetes	P	PFAM Sodium sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
TLS3_k127_261531_1	1150600.ADIARSV_2040	1.031e-76	273.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,4NFEF@976|Bacteroidetes,1IQWZ@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
TLS3_k127_2616329_2	700598.Niako_3963	5.031e-69	236.0	COG3437@1|root,COG4251@1|root,COG3437@2|Bacteria,COG4251@2|Bacteria,4NMAR@976|Bacteroidetes,1IX9J@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
TLS3_k127_2616329_0	700598.Niako_3964	0.0	3309.0	COG0642@1|root,COG0745@1|root,COG0840@1|root,COG1511@1|root,COG2770@1|root,COG0745@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,4NH0W@976|Bacteroidetes,1IV53@117747|Sphingobacteriia	976|Bacteroidetes	T	GAF domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,MCPsignal,PAS_4,PAS_9,Response_reg
TLS3_k127_2616329_3	62928.azo1750	1.072e-05	49.0	COG5487@1|root,COG5487@2|Bacteria,1NE9T@1224|Proteobacteria,2WAN1@28216|Betaproteobacteria,2KXJR@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF1328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
TLS3_k127_2616329_1	1120968.AUBX01000011_gene3193	1.457e-142	463.0	COG5000@1|root,COG5000@2|Bacteria,4NFFM@976|Bacteroidetes,47MZF@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
TLS3_k127_2618120_0	643867.Ftrac_2261	1.294e-161	524.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47NT4@768503|Cytophagia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_26203_0	1237149.C900_00272	1.17e-250	778.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,47JRV@768503|Cytophagia	976|Bacteroidetes	E	PFAM Pyridoxal-dependent decarboxylase, C-terminal sheet domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS3_k127_26203_1	153721.MYP_3536	1.77e-48	183.0	2A8JR@1|root,30XN3@2|Bacteria,4PB4F@976|Bacteroidetes,47V6P@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4412)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4412
TLS3_k127_262230_1	1120968.AUBX01000013_gene3423	5.392e-68	235.0	COG0529@1|root,COG0529@2|Bacteria,4NGCU@976|Bacteroidetes,47NAS@768503|Cytophagia	976|Bacteroidetes	P	Catalyzes the synthesis of activated sulfate	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
TLS3_k127_262230_0	1288963.ADIS_0290	1.759e-166	543.0	COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,4NF52@976|Bacteroidetes,47NEH@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0471 Di- and tricarboxylate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
TLS3_k127_2626478_2	1237149.C900_04066	1.217e-74	261.0	COG1216@1|root,COG1216@2|Bacteria,4NJQR@976|Bacteroidetes,47MWK@768503|Cytophagia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_2626478_1	1237149.C900_03736	1.254e-110	365.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,47JC5@768503|Cytophagia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
TLS3_k127_2626478_0	1237149.C900_03737	1.036e-136	444.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,47MDG@768503|Cytophagia	976|Bacteroidetes	M	PFAM 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
TLS3_k127_26315_6	1124780.ANNU01000006_gene2811	6.191e-75	259.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,47JZN@768503|Cytophagia	976|Bacteroidetes	E	PFAM Shikimate dehydrogenase substrate binding domain	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
TLS3_k127_26315_0	1237149.C900_02379	0.0	1110.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,47KBV@768503|Cytophagia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
TLS3_k127_26315_5	1237149.C900_04820	4.022e-87	291.0	COG1309@1|root,COG1309@2|Bacteria,4NMN2@976|Bacteroidetes	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_C_5,TetR_N
TLS3_k127_26315_4	1237149.C900_00383	1.624e-90	308.0	COG0086@1|root,COG0086@2|Bacteria,4NG2I@976|Bacteroidetes,47Y4X@768503|Cytophagia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_26315_7	1237149.C900_00381	2.825e-73	251.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,47PTY@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_26315_10	1237149.C900_05628	1.913e-17	89.0	2E80N@1|root,332EV@2|Bacteria,4NW5E@976|Bacteroidetes,47S8Q@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_26315_1	1237149.C900_05629	1.579e-209	676.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,47M43@768503|Cytophagia	976|Bacteroidetes	KT	PFAM PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
TLS3_k127_26315_9	1237149.C900_05630	1.112e-50	184.0	COG1695@1|root,COG1695@2|Bacteria,4NSI4@976|Bacteroidetes,47Q8F@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
TLS3_k127_26315_11	1121007.AUML01000027_gene1935	1.327e-11	70.0	2ENN4@1|root,33G9F@2|Bacteria,4NZBT@976|Bacteroidetes,1I6CW@117743|Flavobacteriia,2YJKD@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_26315_3	485918.Cpin_6557	3.006e-102	339.0	COG1246@1|root,COG1246@2|Bacteria,4NGXY@976|Bacteroidetes	976|Bacteroidetes	E	Acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_26315_2	925409.KI911562_gene429	2.917e-203	638.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1INXV@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
TLS3_k127_26315_8	1008457.BAEX01000011_gene1594	7.785e-51	183.0	COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,1HYTR@117743|Flavobacteriia,47GYS@76831|Myroides	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
TLS3_k127_2645975_2	1288963.ADIS_0111	4.071e-98	326.0	COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,47JQQ@768503|Cytophagia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
TLS3_k127_2645975_6	1124780.ANNU01000044_gene520	1.959e-48	180.0	COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,47JBU@768503|Cytophagia	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
TLS3_k127_2645975_4	1237149.C900_04796	1.981e-58	207.0	COG0848@1|root,COG0848@2|Bacteria,4NKT1@976|Bacteroidetes,47PP4@768503|Cytophagia	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
TLS3_k127_2645975_0	1237149.C900_04795	5.52e-162	522.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,47JQM@768503|Cytophagia	976|Bacteroidetes	S	PFAM Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
TLS3_k127_2645975_1	743722.Sph21_2927	1.037e-132	426.0	COG2820@1|root,COG2820@2|Bacteria,4NESQ@976|Bacteroidetes,1IP9I@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
TLS3_k127_2645975_5	929703.KE386491_gene4026	3.051e-50	182.0	COG4096@1|root,COG4096@2|Bacteria,4NNKI@976|Bacteroidetes,47QPJ@768503|Cytophagia	976|Bacteroidetes	V	Type I restriction enzyme R Protein	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
TLS3_k127_2645975_3	1237149.C900_04790	6.591e-91	301.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,47K8G@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
TLS3_k127_2651032_2	1237149.C900_02369	4.465e-57	203.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia	976|Bacteroidetes	DM	TIGRFAM capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
TLS3_k127_2651032_1	1237149.C900_02370	3.361e-75	259.0	COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,47PBY@768503|Cytophagia	976|Bacteroidetes	GM	capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
TLS3_k127_2651032_0	1121481.AUAS01000001_gene4667	2.904e-87	299.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,47M93@768503|Cytophagia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
TLS3_k127_2651032_3	1237149.C900_02372	1.317e-55	198.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,47M8A@768503|Cytophagia	976|Bacteroidetes	NU	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
TLS3_k127_2656581_0	1121904.ARBP01000016_gene5279	0.0	1360.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,47JNC@768503|Cytophagia	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
TLS3_k127_2656581_1	1123278.KB893574_gene6159	8.889e-276	858.0	COG1620@1|root,COG1620@2|Bacteria,4NHVH@976|Bacteroidetes,47Q1C@768503|Cytophagia	976|Bacteroidetes	C	L-lactate permease	lctP	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
TLS3_k127_2656581_2	1123277.KB893176_gene3687	2.038e-09	59.0	COG2225@1|root,COG2225@2|Bacteria,4NF5H@976|Bacteroidetes,47JKU@768503|Cytophagia	976|Bacteroidetes	C	Malate synthase	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
TLS3_k127_2683739_0	1185876.BN8_03539	0.0	1184.0	COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_2683739_2	700598.Niako_2496	7.449e-35	135.0	COG1359@1|root,COG1359@2|Bacteria,4P3Z8@976|Bacteroidetes	976|Bacteroidetes	S	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2683739_1	504472.Slin_2868	6.895e-102	337.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,47PT3@768503|Cytophagia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_2683739_3	504472.Slin_0836	4.465e-22	97.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47JDV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_2695507_2	388413.ALPR1_16718	1.094e-05	48.0	COG0262@1|root,COG0262@2|Bacteria,4NM92@976|Bacteroidetes,47QQZ@768503|Cytophagia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
TLS3_k127_2695507_1	1168034.FH5T_07900	2.692e-26	111.0	2FH9E@1|root,3493R@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2695507_0	1121904.ARBP01000012_gene1193	1.084e-192	629.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_2699577_0	1035193.HMPREF9073_01922	1.666e-14	78.0	COG1649@1|root,COG1649@2|Bacteria,4PNGY@976|Bacteroidetes	2|Bacteria	S	WG containing repeat	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,Cu_amine_oxidN1,GHL10,WG_beta_rep
TLS3_k127_2699577_1	882082.SaccyDRAFT_2758	2.333e-07	65.0	COG4188@1|root,COG4188@2|Bacteria,2I3KQ@201174|Actinobacteria,4DZZ4@85010|Pseudonocardiales	201174|Actinobacteria	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Calx-beta,Chlorophyllase2
TLS3_k127_2707126_1	1356852.N008_14585	1.242e-115	375.0	COG0447@1|root,COG0447@2|Bacteria,4NDXT@976|Bacteroidetes,47JYS@768503|Cytophagia	976|Bacteroidetes	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
TLS3_k127_2707126_0	1124780.ANNU01000019_gene1770	5.307e-171	554.0	COG1165@1|root,COG1165@2|Bacteria,4NETZ@976|Bacteroidetes,47JS5@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
TLS3_k127_2707126_2	1237149.C900_04755	1.582e-75	256.0	COG1169@1|root,COG1169@2|Bacteria,4NF6U@976|Bacteroidetes,47K5Z@768503|Cytophagia	976|Bacteroidetes	HQ	PFAM chorismate binding enzyme	entC	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
TLS3_k127_2726732_0	266265.Bxe_B2662	1.586e-96	320.0	COG3194@1|root,COG3194@2|Bacteria,1RDEE@1224|Proteobacteria,2WB9C@28216|Betaproteobacteria,1K5HC@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Ureidoglycolate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Ureidogly_lyase
TLS3_k127_2726732_3	1048983.EL17_01645	2.336e-32	142.0	COG1620@1|root,COG1620@2|Bacteria,4NHVH@976|Bacteroidetes,47Q1C@768503|Cytophagia	976|Bacteroidetes	C	L-lactate permease	lctP	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
TLS3_k127_2726732_1	616991.JPOO01000001_gene4570	7.985e-53	198.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	uspA	-	-	-	-	-	-	-	-	-	-	-	DUF2007,Usp
TLS3_k127_2726732_2	1461577.CCMH01000016_gene343	5.948e-36	147.0	COG0589@1|root,COG0589@2|Bacteria,4NHXF@976|Bacteroidetes,1HY7W@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_2731423_2	1120973.AQXL01000103_gene2534	3.833e-109	374.0	COG2936@1|root,COG2936@2|Bacteria,1TT0H@1239|Firmicutes,4HC37@91061|Bacilli,278TI@186823|Alicyclobacillaceae	91061|Bacilli	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
TLS3_k127_2731423_1	1469557.JSWF01000014_gene2626	7.932e-146	471.0	COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,1HZRM@117743|Flavobacteriia	976|Bacteroidetes	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
TLS3_k127_2731423_0	760192.Halhy_1593	5.432e-186	590.0	COG0160@1|root,COG0160@2|Bacteria,4NFWF@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS3_k127_2731423_4	1237149.C900_00736	4.424e-98	328.0	COG2126@1|root,COG2126@2|Bacteria,4NEX1@976|Bacteroidetes,47NAG@768503|Cytophagia	976|Bacteroidetes	J	PFAM Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
TLS3_k127_2731423_5	926556.Echvi_1553	2.05e-48	183.0	COG0478@1|root,COG0478@2|Bacteria,4PMVC@976|Bacteroidetes	976|Bacteroidetes	T	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
TLS3_k127_2731423_3	929556.Solca_1014	6.761e-107	361.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1ISIM@117747|Sphingobacteriia	976|Bacteroidetes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_2731423_6	929556.Solca_1013	2.104e-14	74.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1INYC@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
TLS3_k127_2757561_1	1492737.FEM08_05150	1.809e-164	528.0	COG4191@1|root,COG4191@2|Bacteria,4PKDB@976|Bacteroidetes,1IJ83@117743|Flavobacteriia,2NUS8@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
TLS3_k127_2757561_0	1120966.AUBU01000008_gene2384	8.977e-306	974.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Y_Y_Y
TLS3_k127_2757561_2	1249997.JHZW01000003_gene3209	5.141e-111	369.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Reg_prop,Y_Y_Y
TLS3_k127_2775101_0	1502850.FG91_00816	3.829e-148	475.0	COG3177@1|root,COG3177@2|Bacteria,1MX0V@1224|Proteobacteria,2U26G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
TLS3_k127_2775101_2	509191.AEDB02000018_gene272	4.191e-87	296.0	COG0210@1|root,COG0514@1|root,COG0210@2|Bacteria,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,3WHAU@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,DEAD,DUF559,Helicase_C,UvrD_C
TLS3_k127_2775101_1	1202532.FF52_10318	5.282e-91	305.0	COG0457@1|root,COG0457@2|Bacteria,4NMGR@976|Bacteroidetes,1II6P@117743|Flavobacteriia,2P0B5@237|Flavobacterium	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,TPR_8
TLS3_k127_2776264_1	1123276.KB893245_gene1498	2.171e-90	302.0	COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes	976|Bacteroidetes	KLT	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,Big_2,FGE-sulfatase
TLS3_k127_2776264_0	1123277.KB893184_gene4242	2.798e-100	331.0	COG3828@1|root,COG3828@2|Bacteria,4P588@976|Bacteroidetes	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_2776264_3	1124780.ANNU01000020_gene3286	6.577e-05	52.0	COG2319@1|root,COG5184@1|root,COG2319@2|Bacteria,COG5184@2|Bacteria,4NZ4Y@976|Bacteroidetes	976|Bacteroidetes	DZ	IPT/TIG domain	-	-	-	-	-	-	-	-	-	-	-	-	TIG
TLS3_k127_279409_1	1121904.ARBP01000026_gene698	1.805e-84	289.0	COG2207@1|root,COG2207@2|Bacteria,4NE6T@976|Bacteroidetes,47KCW@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
TLS3_k127_279409_4	929556.Solca_0281	3.695e-30	127.0	2B9NZ@1|root,3231D@2|Bacteria,4NR0T@976|Bacteroidetes,1IUNH@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
TLS3_k127_279409_2	880071.Fleli_3299	4.207e-59	214.0	COG2162@1|root,COG2162@2|Bacteria,4NPEY@976|Bacteroidetes,47QTB@768503|Cytophagia	976|Bacteroidetes	Q	Belongs to the arylamine N-acetyltransferase family	nat	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
TLS3_k127_279409_3	485918.Cpin_6024	3.057e-56	198.0	COG4898@1|root,COG4898@2|Bacteria,4NQ4W@976|Bacteroidetes,1IT1D@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
TLS3_k127_279409_0	1121904.ARBP01000014_gene117	6.5e-111	368.0	COG1609@1|root,COG1609@2|Bacteria,4P1CV@976|Bacteroidetes,47T8G@768503|Cytophagia	976|Bacteroidetes	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
TLS3_k127_2821863_1	643867.Ftrac_2626	1.197e-44	168.0	COG4251@1|root,COG4372@1|root,COG4251@2|Bacteria,COG4372@2|Bacteria,4NP5A@976|Bacteroidetes,47PX4@768503|Cytophagia	976|Bacteroidetes	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c
TLS3_k127_2821863_0	1237149.C900_03147	5.122e-285	897.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia	976|Bacteroidetes	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
TLS3_k127_2860789_1	1237149.C900_04093	6.205e-207	648.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia	976|Bacteroidetes	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_2860789_2	1237149.C900_04094	4.286e-162	522.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
TLS3_k127_2860789_0	1123277.KB893172_gene738	4.565e-235	750.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_2879818_6	1121904.ARBP01000009_gene4288	1.181e-53	197.0	COG1216@1|root,COG1216@2|Bacteria,4PKUG@976|Bacteroidetes,47YDT@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GT87
TLS3_k127_2879818_1	1237149.C900_04734	2.485e-203	643.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,47MJK@768503|Cytophagia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_2879818_4	1237149.C900_04733	1.764e-105	346.0	COG1215@1|root,COG1215@2|Bacteria,4NFM1@976|Bacteroidetes,47M1F@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_2879818_0	1121904.ARBP01000006_gene3716	5.432e-258	807.0	COG0348@1|root,COG0348@2|Bacteria,4NHSX@976|Bacteroidetes,47KC5@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S dicluster domain	yccM_2	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7,Fer4_9
TLS3_k127_2879818_2	1237149.C900_02900	3.244e-197	623.0	COG0446@1|root,COG0446@2|Bacteria,4NET1@976|Bacteroidetes,47JW2@768503|Cytophagia	976|Bacteroidetes	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
TLS3_k127_2879818_5	1237149.C900_03812	2.146e-84	286.0	COG0398@1|root,COG0398@2|Bacteria,4NHA2@976|Bacteroidetes,47S54@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
TLS3_k127_2879818_3	1150600.ADIARSV_3084	7.859e-133	430.0	COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,1IPKK@117747|Sphingobacteriia	976|Bacteroidetes	G	COGs COG0058 Glucan phosphorylase	glgP	-	2.4.1.1,2.4.1.8	ko:K00688,ko:K00691	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R01555,R02111	RC00049	ko00000,ko00001,ko01000	-	GH65,GT35	-	DUF3417,Phosphorylase
TLS3_k127_288825_3	926549.KI421517_gene865	7.303e-39	149.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,47NI9@768503|Cytophagia	976|Bacteroidetes	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
TLS3_k127_288825_2	1237149.C900_01722	3.65e-67	237.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,47K36@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
TLS3_k127_288825_1	1237149.C900_01723	1.66e-102	347.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,47N37@768503|Cytophagia	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_288825_0	1237149.C900_01724	6.585e-113	379.0	COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,47MJ6@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
TLS3_k127_288825_4	1434325.AZQN01000002_gene1175	1.903e-05	49.0	COG3117@1|root,COG3117@2|Bacteria,4NRIN@976|Bacteroidetes,47R6J@768503|Cytophagia	976|Bacteroidetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
TLS3_k127_288868_1	251221.35211147	1.697e-53	209.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,1G1EB@1117|Cyanobacteria	1117|Cyanobacteria	KLT	serine threonine protein kinase	-	-	2.7.1.37,2.7.11.1	ko:K00870,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase,TPR_11,TPR_16,TPR_8
TLS3_k127_288868_0	1121481.AUAS01000001_gene4744	6.907e-185	585.0	COG1506@1|root,COG1506@2|Bacteria,4PKQ3@976|Bacteroidetes,47XYQ@768503|Cytophagia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Peptidase_S9
TLS3_k127_2915612_1	1237149.C900_01083	1.525e-71	244.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,47KMP@768503|Cytophagia	976|Bacteroidetes	E	PFAM Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
TLS3_k127_2915612_0	1237149.C900_01087	1.221e-314	971.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,47M2W@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
TLS3_k127_2915612_2	1237149.C900_01088	8.456e-68	237.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,47JIS@768503|Cytophagia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2917096_0	1237149.C900_03773	2.753e-141	461.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,47JU5@768503|Cytophagia	976|Bacteroidetes	D	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
TLS3_k127_2917096_3	1239962.C943_00992	3.08e-38	154.0	2C852@1|root,32YB2@2|Bacteria,4NM63@976|Bacteroidetes,47S6T@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
TLS3_k127_2917096_2	880070.Cycma_1738	4.502e-63	218.0	COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,47PUX@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
TLS3_k127_2917096_1	1121904.ARBP01000005_gene4599	2.425e-103	347.0	COG4857@1|root,COG4857@2|Bacteria,4NHKI@976|Bacteroidetes,47JME@768503|Cytophagia	976|Bacteroidetes	S	Phosphotransferase enzyme family	mtnK	-	2.7.1.100	ko:K00899	ko00270,ko01100,map00270,map01100	M00034	R04143	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
TLS3_k127_293694_2	869213.JCM21142_1607	2.934e-35	153.0	COG2335@1|root,COG2335@2|Bacteria,4NI6Z@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Fasciclin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4993,Fasciclin
TLS3_k127_293694_3	1408813.AYMG01000006_gene4238	6.21e-17	93.0	COG2335@1|root,COG2335@2|Bacteria,4NGU3@976|Bacteroidetes,1IUNS@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Fasciclin domain	-	-	-	ko:K19519	-	-	-	-	ko00000,ko04516	-	-	-	DUF5108,Fasciclin
TLS3_k127_293694_1	998674.ATTE01000001_gene3243	9.892e-142	462.0	COG1373@1|root,COG1373@2|Bacteria,1MWDX@1224|Proteobacteria,1RYD6@1236|Gammaproteobacteria,460VV@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
TLS3_k127_293694_0	760192.Halhy_0549	5.433e-185	581.0	28JP4@1|root,2Z9F6@2|Bacteria,4NDYM@976|Bacteroidetes,1IVSV@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2940890_0	694427.Palpr_2669	6.122e-207	655.0	COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes,2FMEB@200643|Bacteroidia,22XAH@171551|Porphyromonadaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_2940890_2	694427.Palpr_2672	4.785e-26	111.0	2EBJZ@1|root,335KD@2|Bacteria,4NWP2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2940890_1	694427.Palpr_2673	5.745e-31	126.0	2EC34@1|root,33623@2|Bacteria,4NVW7@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
TLS3_k127_2940890_3	694427.Palpr_2674	1.316e-13	74.0	COG4980@1|root,COG4980@2|Bacteria,4NW56@976|Bacteroidetes,2FZ4H@200643|Bacteroidia	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
TLS3_k127_2948001_2	1189612.A33Q_2380	1.597e-55	205.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47U6P@768503|Cytophagia	976|Bacteroidetes	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SnoaL_3
TLS3_k127_2948001_1	468059.AUHA01000002_gene129	1.235e-78	266.0	COG0494@1|root,COG0494@2|Bacteria,4NHER@976|Bacteroidetes,1IRG1@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM NUDIX hydrolase	nudK	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_2948001_3	1168289.AJKI01000031_gene1095	7.3e-53	193.0	COG0349@1|root,COG0349@2|Bacteria,4NP3B@976|Bacteroidetes,2FN2U@200643|Bacteroidia,3XJDC@558415|Marinilabiliaceae	976|Bacteroidetes	J	3'-5' exonuclease	rnd	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A_exo1
TLS3_k127_2948001_0	761193.Runsl_1508	6.1e-240	750.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,47JF7@768503|Cytophagia	976|Bacteroidetes	E	PFAM amino acid permease-associated region	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
TLS3_k127_2954023_0	997346.HMPREF9374_0539	5.919e-92	311.0	COG4974@1|root,COG4974@2|Bacteria,1TQ3R@1239|Firmicutes,4HD6N@91061|Bacilli,27BVZ@186824|Thermoactinomycetaceae	91061|Bacilli	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
TLS3_k127_2954023_1	545693.BMQ_3575	1.01e-87	298.0	COG4974@1|root,COG4974@2|Bacteria,1TQXV@1239|Firmicutes,4HFGC@91061|Bacilli,1ZFQ2@1386|Bacillus	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
TLS3_k127_2954023_3	1347369.CCAD010000067_gene3452	2.985e-09	57.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli,1ZJWT@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2958972_8	1273538.G159_19185	1.645e-12	78.0	COG1396@1|root,COG1396@2|Bacteria,1V8MN@1239|Firmicutes,4HK71@91061|Bacilli	91061|Bacilli	K	Helix-turn-helix	-	-	-	ko:K20480	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_19,HTH_3
TLS3_k127_2958972_2	643867.Ftrac_0364	1.368e-128	422.0	COG0644@1|root,COG0644@2|Bacteria,4NKR8@976|Bacteroidetes,47SE4@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM geranylgeranyl reductase family	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3,Trp_halogenase
TLS3_k127_2958972_1	1267535.KB906767_gene4768	6.513e-150	488.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2958972_6	714943.Mucpa_5576	6.013e-38	149.0	2E3RG@1|root,32YP4@2|Bacteria,4NUUF@976|Bacteroidetes,1ITK6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2958972_4	1408813.AYMG01000031_gene1456	1.522e-74	258.0	COG2207@1|root,COG2207@2|Bacteria,4NHA5@976|Bacteroidetes,1IWNM@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_2958972_0	1237149.C900_02981	2.533e-188	599.0	COG1690@1|root,COG1690@2|Bacteria,4NG8T@976|Bacteroidetes,47N9X@768503|Cytophagia	976|Bacteroidetes	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
TLS3_k127_2958972_7	1313301.AUGC01000001_gene1643	4.677e-17	87.0	COG4783@1|root,COG4783@2|Bacteria,4NTS7@976|Bacteroidetes	976|Bacteroidetes	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
TLS3_k127_2958972_3	880071.Fleli_2454	5.513e-107	358.0	COG1996@1|root,COG1996@2|Bacteria,4NFZ3@976|Bacteroidetes	976|Bacteroidetes	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2958972_5	870967.VIS19158_14582	8.764e-39	148.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,1S1VG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,HTH_17,SHOCT
TLS3_k127_2959729_1	1122605.KB893625_gene1745	2.919e-95	319.0	COG1409@1|root,COG1409@2|Bacteria,4NN8T@976|Bacteroidetes,1IR4Y@117747|Sphingobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
TLS3_k127_2959729_0	1237149.C900_02110	3.217e-107	352.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,47KKV@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
TLS3_k127_2964109_2	153721.MYP_898	1.012e-115	377.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,47THR@768503|Cytophagia	976|Bacteroidetes	L	Endonuclease/Exonuclease/phosphatase family	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
TLS3_k127_2964109_0	1237149.C900_04866	1.771e-227	709.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,47JQ7@768503|Cytophagia	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
TLS3_k127_2964109_3	1237149.C900_04865	3.723e-77	266.0	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,47PZX@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
TLS3_k127_2964109_1	1237149.C900_04864	4.984e-118	383.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,47JMH@768503|Cytophagia	976|Bacteroidetes	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
TLS3_k127_2974890_1	485918.Cpin_0084	1.488e-63	221.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1INUJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
TLS3_k127_2974890_0	236814.IX39_16880	1.854e-112	368.0	COG1409@1|root,COG1409@2|Bacteria,4NNCZ@976|Bacteroidetes,1I4VN@117743|Flavobacteriia,3ZPR5@59732|Chryseobacterium	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
TLS3_k127_2974890_3	1122244.AUGF01000005_gene1177	3.256e-14	73.0	COG1502@1|root,COG1502@2|Bacteria,1Q5N5@1224|Proteobacteria,1RYW1@1236|Gammaproteobacteria,3NKZT@468|Moraxellaceae	1236|Gammaproteobacteria	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
TLS3_k127_2974890_2	411154.GFO_0916	1.341e-28	116.0	COG1502@1|root,COG1502@2|Bacteria,4NN1I@976|Bacteroidetes,1I2F3@117743|Flavobacteriia	976|Bacteroidetes	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
TLS3_k127_2979576_10	761193.Runsl_4441	3.874e-95	316.0	COG1649@1|root,COG1649@2|Bacteria,4NJ20@976|Bacteroidetes,47NNM@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL6
TLS3_k127_2979576_2	1121481.AUAS01000005_gene1778	0.0	1184.0	COG2010@1|root,COG2010@2|Bacteria,4NEPV@976|Bacteroidetes,47M4N@768503|Cytophagia	976|Bacteroidetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
TLS3_k127_2979576_3	1454007.JAUG01000019_gene1159	2.552e-286	883.0	COG4102@1|root,COG4102@2|Bacteria,4NE73@976|Bacteroidetes,1IQYR@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TLS3_k127_2979576_4	1121481.AUAS01000005_gene1776	4.376e-250	791.0	COG4886@1|root,COG4886@2|Bacteria,4NG07@976|Bacteroidetes,47K53@768503|Cytophagia	976|Bacteroidetes	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Fn3_assoc,PSCyt1
TLS3_k127_2979576_0	1123248.KB893370_gene5141	0.0	1692.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG2755@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,4NEQA@976|Bacteroidetes,1J0QI@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,HEAT_2,Lipase_GDSL_2
TLS3_k127_2979576_7	509635.N824_22715	4.411e-142	455.0	COG3828@1|root,COG3828@2|Bacteria,4NJK6@976|Bacteroidetes,1IR19@117747|Sphingobacteriia	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
TLS3_k127_2979576_8	504472.Slin_1263	4.034e-128	416.0	COG1082@1|root,COG1082@2|Bacteria,4NHGW@976|Bacteroidetes,47MTJ@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.30,5.1.3.31	ko:K18910	-	-	R10817,R10818	RC03111,RC03283	ko00000,ko01000	-	-	-	AP_endonuc_2,AP_endonuc_2_N
TLS3_k127_2979576_1	761193.Runsl_0627	0.0	1217.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NH6W@976|Bacteroidetes,47K4F@768503|Cytophagia	976|Bacteroidetes	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TLS3_k127_2979576_9	143224.JQMD01000002_gene1739	5.51e-105	349.0	COG2133@1|root,COG2133@2|Bacteria,4NFXB@976|Bacteroidetes,1I02S@117743|Flavobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_2979576_6	1185876.BN8_00375	8.153e-172	544.0	COG2017@1|root,COG2017@2|Bacteria,4NHQH@976|Bacteroidetes,47JMF@768503|Cytophagia	976|Bacteroidetes	G	Domain of unknown function (DUF4432)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4432
TLS3_k127_2979576_5	1185876.BN8_00376	2.15e-242	751.0	COG1482@1|root,COG1482@2|Bacteria,4NGGP@976|Bacteroidetes,47NZ6@768503|Cytophagia	976|Bacteroidetes	G	cell wall glycoprotein biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2997995_0	1237149.C900_04990	7.695e-264	829.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,47JAK@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
TLS3_k127_2997995_1	1237149.C900_04988	5.636e-48	177.0	COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,47Q5N@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
TLS3_k127_2998946_7	641526.ADIWIN_3131	1.745e-66	257.0	COG2133@1|root,COG2911@1|root,COG2133@2|Bacteria,COG2911@2|Bacteria,4PMMV@976|Bacteroidetes,1IMVC@117743|Flavobacteriia	976|Bacteroidetes	E	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2998946_5	1313421.JHBV01000042_gene3261	6.292e-83	308.0	COG2353@1|root,COG3210@1|root,COG2353@2|Bacteria,COG3210@2|Bacteria,4NIDX@976|Bacteroidetes	976|Bacteroidetes	U	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_2998946_6	269798.CHU_0457	3.108e-73	258.0	COG4850@1|root,COG4850@2|Bacteria,4NFZ6@976|Bacteroidetes,47N06@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
TLS3_k127_2998946_3	1408473.JHXO01000007_gene976	5.857e-97	325.0	COG1597@1|root,COG1597@2|Bacteria,4NJ68@976|Bacteroidetes,2FXIK@200643|Bacteroidia	976|Bacteroidetes	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
TLS3_k127_2998946_4	471854.Dfer_1402	2.533e-88	299.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,4NJH3@976|Bacteroidetes,47UK1@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_18
TLS3_k127_2998946_0	929556.Solca_3967	3.913e-251	800.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1IR9D@117747|Sphingobacteriia	976|Bacteroidetes	G	hydrolase family 20, catalytic	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX,CHB_HEX_C,Glyco_hydro_20,Glyco_hydro_20b
TLS3_k127_2998946_2	1121904.ARBP01000006_gene3917	5.896e-150	480.0	COG5285@1|root,COG5285@2|Bacteria,4NHQ6@976|Bacteroidetes,47NC5@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
TLS3_k127_2998946_1	1123234.AUKI01000011_gene1438	4.211e-236	747.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1HWWU@117743|Flavobacteriia	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
TLS3_k127_3012332_2	1237149.C900_04099	6.097e-35	136.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,47PRC@768503|Cytophagia	976|Bacteroidetes	J	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
TLS3_k127_3012332_1	1120968.AUBX01000010_gene1176	2.034e-157	501.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,47JX0@768503|Cytophagia	976|Bacteroidetes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
TLS3_k127_3012332_0	1237149.C900_04102	0.0	1113.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,47KQP@768503|Cytophagia	976|Bacteroidetes	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
TLS3_k127_3017303_0	203275.BFO_2015	1.014e-197	619.0	COG3754@1|root,COG3754@2|Bacteria,4P1NY@976|Bacteroidetes,2FRFT@200643|Bacteroidia,22X51@171551|Porphyromonadaceae	976|Bacteroidetes	M	Glycosyltransferase WbsX	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WbsX
TLS3_k127_3017303_1	1305737.JAFX01000001_gene3155	9.902e-117	384.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,47UAQ@768503|Cytophagia	976|Bacteroidetes	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
TLS3_k127_3020069_2	926556.Echvi_0152	2.916e-44	161.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,47JG6@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
TLS3_k127_3020069_0	1237149.C900_04417	7.912e-132	441.0	COG0683@1|root,COG0683@2|Bacteria,4PKN8@976|Bacteroidetes,47NJW@768503|Cytophagia	976|Bacteroidetes	E	PFAM Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
TLS3_k127_3020069_1	313596.RB2501_12042	4.357e-89	302.0	28HDX@1|root,2Z7QG@2|Bacteria,4NFID@976|Bacteroidetes,1HZD2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_302011_4	1237149.C900_01113	1.813e-51	189.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
TLS3_k127_302011_2	1189612.A33Q_3833	6.457e-186	593.0	COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,47KR6@768503|Cytophagia	976|Bacteroidetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
TLS3_k127_302011_3	1237149.C900_00733	2.783e-67	244.0	COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,47JP5@768503|Cytophagia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase N-terminal domain subunit	mutA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
TLS3_k127_302011_0	1237149.C900_00734	0.0	1094.0	COG2185@1|root,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,47JW5@768503|Cytophagia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
TLS3_k127_302011_1	1237149.C900_00735	3.943e-282	895.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,47N11@768503|Cytophagia	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12
TLS3_k127_3022983_2	1237149.C900_02181	1.574e-67	231.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,47KVF@768503|Cytophagia	976|Bacteroidetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
TLS3_k127_3022983_0	1237149.C900_02182	5.533e-172	548.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,47JI5@768503|Cytophagia	976|Bacteroidetes	S	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
TLS3_k127_3022983_1	1237149.C900_02183	1.928e-156	498.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,47J9Z@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
TLS3_k127_3050422_0	641524.ADICYQ_0082	0.0	1042.0	COG2352@1|root,COG2352@2|Bacteria,4NFC0@976|Bacteroidetes,47NF0@768503|Cytophagia	976|Bacteroidetes	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
TLS3_k127_3050422_1	761193.Runsl_3819	3.083e-28	118.0	2CG1Y@1|root,333IH@2|Bacteria,4NVMK@976|Bacteroidetes,47RKN@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
TLS3_k127_3060303_3	1237149.C900_03981	5.666e-32	125.0	COG0852@1|root,COG0852@2|Bacteria,4NPGA@976|Bacteroidetes,47PNZ@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
TLS3_k127_3060303_0	1237149.C900_03982	2.273e-221	690.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,47JZW@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
TLS3_k127_3060303_1	1237149.C900_03983	3.25e-155	504.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,47JYX@768503|Cytophagia	976|Bacteroidetes	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
TLS3_k127_3060303_2	1118054.CAGW01000015_gene4585	1.358e-90	304.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,4HA1R@91061|Bacilli,26UBS@186822|Paenibacillaceae	91061|Bacilli	E	Threonine aldolase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
TLS3_k127_3060807_2	1123278.KB893458_gene719	1.132e-32	138.0	COG2819@1|root,COG2819@2|Bacteria,4NGNJ@976|Bacteroidetes	976|Bacteroidetes	S	Putative esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
TLS3_k127_3060807_3	1443665.JACA01000013_gene4113	2.315e-31	127.0	2AVBG@1|root,31M2S@2|Bacteria,4NQIJ@976|Bacteroidetes,1I3P4@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3060807_1	1499968.TCA2_4279	3.694e-33	132.0	COG5646@1|root,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,4HINV@91061|Bacilli,26YRN@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_3060807_0	1279009.ADICEAN_00932	2.486e-103	339.0	COG0740@1|root,COG0740@2|Bacteria,4NK03@976|Bacteroidetes	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
TLS3_k127_3071209_3	643867.Ftrac_3153	9.252e-06	51.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,47MGN@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_3071209_0	1237149.C900_01598	2.62e-142	459.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,47MUX@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_3071209_2	1341181.FLJC2902T_27420	8.316e-32	128.0	COG2315@1|root,COG2315@2|Bacteria,4NTRF@976|Bacteroidetes,1ID1Z@117743|Flavobacteriia,2NWYS@237|Flavobacterium	976|Bacteroidetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
TLS3_k127_3071209_1	1185876.BN8_04246	2.428e-54	193.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,47QER@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
TLS3_k127_3072179_6	203275.BFO_2828	2.562e-35	138.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,2FM2B@200643|Bacteroidia,22X69@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
TLS3_k127_3072179_4	1237149.C900_03679	1.651e-92	312.0	COG0697@1|root,COG0697@2|Bacteria,4NE8D@976|Bacteroidetes,47JNH@768503|Cytophagia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_3072179_1	1237149.C900_03678	7.135e-137	445.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,47JHT@768503|Cytophagia	976|Bacteroidetes	S	Permease YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
TLS3_k127_3072179_0	388413.ALPR1_04783	1.29e-203	638.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,47JEY@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
TLS3_k127_3072179_2	1048983.EL17_09325	6.954e-115	381.0	COG1609@1|root,COG1609@2|Bacteria,4NE81@976|Bacteroidetes,47P3S@768503|Cytophagia	976|Bacteroidetes	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_4
TLS3_k127_3072179_3	1237149.C900_03673	7.783e-100	337.0	COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,47JZE@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_3072179_5	1237149.C900_03672	1.555e-62	219.0	COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes,47JCE@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_3080339_6	509635.N824_22865	8.379e-11	67.0	COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,1ISFF@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_3080339_4	1178825.ALIH01000004_gene2863	2.039e-75	261.0	COG3485@1|root,COG3485@2|Bacteria,4NEZ1@976|Bacteroidetes,1I01Q@117743|Flavobacteriia	976|Bacteroidetes	Q	Dioxygenase	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
TLS3_k127_3080339_3	1469557.JSWF01000032_gene3248	1.659e-79	276.0	COG1073@1|root,COG1073@2|Bacteria,4NGG4@976|Bacteroidetes	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
TLS3_k127_3080339_0	1123248.KB893386_gene1814	8.056e-207	651.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,1INUE@117747|Sphingobacteriia	976|Bacteroidetes	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
TLS3_k127_3080339_5	1443665.JACA01000024_gene3341	4.424e-50	184.0	COG1335@1|root,COG1335@2|Bacteria,4NP7C@976|Bacteroidetes,1I299@117743|Flavobacteriia,2YIF5@290174|Aquimarina	976|Bacteroidetes	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
TLS3_k127_3080339_1	391596.PBAL39_12082	9.019e-145	466.0	COG0624@1|root,COG0624@2|Bacteria,4NE2G@976|Bacteroidetes,1IQBT@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
TLS3_k127_3080339_2	1123248.KB893386_gene1816	1.443e-103	342.0	COG0548@1|root,COG0548@2|Bacteria,4NDY8@976|Bacteroidetes,1IPBE@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
TLS3_k127_3085345_0	1237149.C900_03756	0.0	1431.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,47KQD@768503|Cytophagia	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	ko:K21397	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,TerB
TLS3_k127_3085345_4	1237149.C900_03757	4.935e-64	220.0	2CEYK@1|root,31W5M@2|Bacteria,4NQEQ@976|Bacteroidetes,47R7M@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
TLS3_k127_3085345_3	1237149.C900_03758	6.578e-71	243.0	2AAU0@1|root,3106Q@2|Bacteria,4NNSV@976|Bacteroidetes,47Q0I@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3085345_1	1237149.C900_03759	0.0	1372.0	COG2202@1|root,COG2203@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,4NIXZ@976|Bacteroidetes,47MCW@768503|Cytophagia	976|Bacteroidetes	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,PAS,PAS_4,PAS_9,SpoIIE
TLS3_k127_3085345_6	1237149.C900_03760	1.832e-40	160.0	COG3605@1|root,COG3605@2|Bacteria,4P41N@976|Bacteroidetes,47VIK@768503|Cytophagia	976|Bacteroidetes	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
TLS3_k127_3085345_2	1124780.ANNU01000049_gene2202	7.721e-92	304.0	COG2201@1|root,COG2201@2|Bacteria,4NNR3@976|Bacteroidetes,47PAB@768503|Cytophagia	976|Bacteroidetes	NT	CheB methylesterase	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
TLS3_k127_3085345_5	1237149.C900_03762	5.958e-49	175.0	COG1352@1|root,COG1352@2|Bacteria,4NFDS@976|Bacteroidetes,47JV5@768503|Cytophagia	976|Bacteroidetes	NT	PFAM MCP methyltransferase CheR-type	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
TLS3_k127_3087306_1	1123248.KB893348_gene328	8.286e-303	936.0	COG2303@1|root,COG2303@2|Bacteria,4NEHP@976|Bacteroidetes	976|Bacteroidetes	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
TLS3_k127_3087306_5	1124780.ANNU01000017_gene1931	2.184e-34	133.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,47RUP@768503|Cytophagia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
TLS3_k127_3087306_3	1237149.C900_03333	1.397e-235	739.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,47MAW@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
TLS3_k127_3087306_0	929562.Emtol_1222	0.0	1396.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,47KDP@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_3087306_2	471854.Dfer_4947	5.343e-246	772.0	COG0561@1|root,COG0561@2|Bacteria,4PKHD@976|Bacteroidetes,47KAD@768503|Cytophagia	976|Bacteroidetes	S	PFAM RagB SusD domain protein	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_3087306_4	1189612.A33Q_3407	1.904e-115	379.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47JJ5@768503|Cytophagia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
TLS3_k127_3093903_1	1237149.C900_04588	1.359e-131	423.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,47JYP@768503|Cytophagia	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
TLS3_k127_3093903_2	1237149.C900_04589	5.895e-114	376.0	COG0226@1|root,COG0226@2|Bacteria,4NKND@976|Bacteroidetes,47PVA@768503|Cytophagia	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_3093903_0	1237149.C900_04590	1.779e-200	627.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,47KHB@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated lipoprotein GldK	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TLS3_k127_3095162_7	929703.KE386491_gene3140	3.686e-31	128.0	COG0526@1|root,COG0526@2|Bacteria,4NSJ1@976|Bacteroidetes,47XHE@768503|Cytophagia	976|Bacteroidetes	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin,Thioredoxin_8
TLS3_k127_3095162_9	1120968.AUBX01000009_gene737	8.138e-11	63.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,47JS7@768503|Cytophagia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
TLS3_k127_3095162_1	866536.Belba_2255	6.007e-216	679.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,47MPX@768503|Cytophagia	976|Bacteroidetes	J	TIGRFAM MiaB-like tRNA modifying enzyme	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
TLS3_k127_3095162_8	1121904.ARBP01000002_gene6681	1.848e-14	79.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
TLS3_k127_3095162_2	1237149.C900_05646	7.472e-214	679.0	COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,47KI8@768503|Cytophagia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgcA	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TLS3_k127_3095162_6	1237149.C900_05647	1.418e-36	142.0	2DN0J@1|root,32UI3@2|Bacteria,4NT4U@976|Bacteroidetes,47R55@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3095162_3	1124780.ANNU01000032_gene1270	1.016e-160	511.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,47JNM@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
TLS3_k127_3095162_4	1237149.C900_03719	7.008e-89	305.0	2CG1Y@1|root,2Z9QX@2|Bacteria,4NJI6@976|Bacteroidetes,47PFJ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
TLS3_k127_3095162_0	1237149.C900_05076	7.017e-236	733.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,47KQK@768503|Cytophagia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_3095162_5	1237149.C900_05077	7.452e-86	289.0	COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,47KCQ@768503|Cytophagia	976|Bacteroidetes	E	Tryptophan 2,3-dioxygenase	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
TLS3_k127_309958_3	926549.KI421517_gene3869	2.818e-38	151.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,47NAQ@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_309958_4	746697.Aeqsu_1794	2.305e-24	112.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,1HX4T@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_7,TPR_8
TLS3_k127_309958_0	1124780.ANNU01000010_gene3751	5.867e-130	423.0	COG0668@1|root,COG0668@2|Bacteria,4NHU7@976|Bacteroidetes,47P5J@768503|Cytophagia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
TLS3_k127_309958_2	313606.M23134_01223	1.344e-68	240.0	COG3034@1|root,COG3034@2|Bacteria,4NNK3@976|Bacteroidetes,47PW3@768503|Cytophagia	976|Bacteroidetes	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C,YkuD
TLS3_k127_309958_1	1279009.ADICEAN_00906	6.704e-125	421.0	COG1305@1|root,COG1305@2|Bacteria,4PMBI@976|Bacteroidetes,47YQ0@768503|Cytophagia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857
TLS3_k127_3100924_0	1121097.JCM15093_1431	8.088e-64	226.0	COG3279@1|root,COG3279@2|Bacteria,4NF8U@976|Bacteroidetes,2FMI5@200643|Bacteroidia,4APR4@815|Bacteroidaceae	976|Bacteroidetes	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_3100924_2	1122176.KB903538_gene1486	9.191e-42	168.0	COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,1ISFF@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_3100924_3	204669.Acid345_1456	1.377e-41	157.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
TLS3_k127_3100924_4	204669.Acid345_3584	1.674e-30	125.0	COG0346@1|root,COG0346@2|Bacteria,3Y5YF@57723|Acidobacteria,2JNP7@204432|Acidobacteriia	204432|Acidobacteriia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_3100924_1	509635.N824_01270	6.809e-47	170.0	2CDZ7@1|root,2Z8VK@2|Bacteria,4NIYY@976|Bacteroidetes,1IXMQ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3107535_0	761193.Runsl_2739	0.0	1466.0	COG4206@1|root,COG4774@1|root,COG4206@2|Bacteria,COG4774@2|Bacteria,4NZWU@976|Bacteroidetes	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
TLS3_k127_3107535_2	880070.Cycma_2059	1.19e-105	349.0	COG1940@1|root,COG1940@2|Bacteria,4NJ71@976|Bacteroidetes,47MF1@768503|Cytophagia	976|Bacteroidetes	GK	PFAM ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
TLS3_k127_3107535_1	504472.Slin_6586	9.028e-319	990.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,47JFD@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 20, catalytic core	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX,CHB_HEX_C,Glyco_hydro_20,Glyco_hydro_20b
TLS3_k127_311391_3	714943.Mucpa_4137	5.776e-44	167.0	COG1309@1|root,COG1309@2|Bacteria,4NNK5@976|Bacteroidetes,1ISU5@117747|Sphingobacteriia	976|Bacteroidetes	K	Regulatory protein tetr	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
TLS3_k127_311391_0	269798.CHU_1586	2.869e-179	569.0	COG0304@1|root,COG0304@2|Bacteria,4NDVU@976|Bacteroidetes,47K25@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_311391_1	1237149.C900_03288	4.421e-120	391.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,47K20@768503|Cytophagia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
TLS3_k127_311391_2	1237149.C900_03289	1.008e-103	342.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,47N59@768503|Cytophagia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
TLS3_k127_311391_4	1124780.ANNU01000003_gene1418	2.124e-18	87.0	COG4221@1|root,COG4221@2|Bacteria,4NG8J@976|Bacteroidetes,47M5I@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_3129276_3	1237149.C900_04546	4.954e-41	158.0	2DPU6@1|root,333E2@2|Bacteria,4NW9K@976|Bacteroidetes,47RVJ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3129276_0	509635.N824_09780	1.47e-260	807.0	COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes	976|Bacteroidetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
TLS3_k127_3129276_2	926562.Oweho_3286	8.845e-50	183.0	COG1514@1|root,COG1514@2|Bacteria,4NTUH@976|Bacteroidetes,1I48G@117743|Flavobacteriia	976|Bacteroidetes	J	2',5' RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
TLS3_k127_3129276_1	1121904.ARBP01000028_gene1643	5.56e-54	193.0	COG2515@1|root,COG2515@2|Bacteria,4NEP9@976|Bacteroidetes,47JNZ@768503|Cytophagia	976|Bacteroidetes	E	1-aminocyclopropane-1-carboxylate deaminase	acdS	-	3.5.99.7	ko:K01505	ko00270,map00270	-	R00997	RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
TLS3_k127_3135177_3	1237149.C900_04037	2.108e-27	113.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia	976|Bacteroidetes	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_3135177_2	1237149.C900_04036	1.108e-126	419.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
TLS3_k127_3135177_6	1229172.JQFA01000002_gene3006	0.000134	47.0	COG4338@1|root,COG4338@2|Bacteria,1G9XH@1117|Cyanobacteria,1HDAQ@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF3253)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3253
TLS3_k127_3135177_4	929562.Emtol_3894	6.382e-12	71.0	2EBK0@1|root,335KF@2|Bacteria,4PNPM@976|Bacteroidetes,47SCQ@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_3135177_1	1237149.C900_02057	3.049e-173	548.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,47MPT@768503|Cytophagia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS3_k127_3135177_0	1121904.ARBP01000006_gene3816	3.375e-209	661.0	COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,4NHVG@976|Bacteroidetes,47M7T@768503|Cytophagia	976|Bacteroidetes	CG	TIGRFAM membrane-bound dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH,HEAT_2
TLS3_k127_3141028_3	1123248.KB893370_gene5139	9.179e-109	356.0	2DB9P@1|root,2Z7Y1@2|Bacteria,4NHQN@976|Bacteroidetes,1IPTB@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_3141028_1	1237149.C900_00002	5.48e-163	517.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,47JPY@768503|Cytophagia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
TLS3_k127_3141028_2	643867.Ftrac_0183	1.14e-147	472.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,47JCR@768503|Cytophagia	976|Bacteroidetes	S	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_3141028_4	1120968.AUBX01000010_gene931	1.68e-76	264.0	COG1752@1|root,COG1752@2|Bacteria,4NERH@976|Bacteroidetes,47JZ5@768503|Cytophagia	976|Bacteroidetes	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
TLS3_k127_3141028_0	1237149.C900_00005	0.0	1041.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,47K5S@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
TLS3_k127_3141028_5	1229276.DI53_3347	0.0001461	47.0	COG3047@1|root,COG3047@2|Bacteria,4PPHC@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_3161552_3	1237149.C900_03447	1.656e-67	236.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
TLS3_k127_3161552_6	1237149.C900_03448	2.618e-24	103.0	COG1918@1|root,COG1918@2|Bacteria,4NUWI@976|Bacteroidetes,47RUN@768503|Cytophagia	976|Bacteroidetes	P	FeoA	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
TLS3_k127_3161552_0	1237149.C900_00798	3.415e-284	895.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,47JKP@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
TLS3_k127_3161552_5	1381123.AYOD01000059_gene1666	5.609e-42	159.0	COG0073@1|root,COG0073@2|Bacteria,1RGU7@1224|Proteobacteria,2U9AH@28211|Alphaproteobacteria,43KH2@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	Export-related chaperone CsaA	csaA	GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
TLS3_k127_3161552_1	1237149.C900_00804	8.269e-113	368.0	COG0106@1|root,COG0106@2|Bacteria,4NK0E@976|Bacteroidetes,47NT9@768503|Cytophagia	976|Bacteroidetes	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
TLS3_k127_3161552_2	1237149.C900_03498	1.411e-109	373.0	COG2885@1|root,COG2885@2|Bacteria,4NJB2@976|Bacteroidetes,47K81@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_3161552_4	1237149.C900_03497	2.36e-59	211.0	COG0457@1|root,COG0457@2|Bacteria,4NRIH@976|Bacteroidetes,47QEH@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
TLS3_k127_3161552_7	1000565.METUNv1_03293	1.407e-17	83.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2VRA6@28216|Betaproteobacteria,2KWBF@206389|Rhodocyclales	206389|Rhodocyclales	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
TLS3_k127_3169068_0	269799.Gmet_1075	1.007e-109	365.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2WJ2S@28221|Deltaproteobacteria,43S6W@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB36H	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
TLS3_k127_3169068_2	869213.JCM21142_452	4.809e-29	122.0	COG1871@1|root,COG1871@2|Bacteria,4NQUM@976|Bacteroidetes,47V8R@768503|Cytophagia	976|Bacteroidetes	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	-	-	-	-	-	-	-	-	-	-	CheD
TLS3_k127_3169068_1	869213.JCM21142_450	1.138e-66	232.0	COG1352@1|root,COG1352@2|Bacteria,4NJ75@976|Bacteroidetes,47RGQ@768503|Cytophagia	976|Bacteroidetes	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
TLS3_k127_3170856_1	1121904.ARBP01000048_gene4124	1.274e-05	51.0	2E4BN@1|root,32Z79@2|Bacteria,4NXNH@976|Bacteroidetes,47VXU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3170856_0	1347086.CCBA010000031_gene968	1.433e-23	112.0	COG2202@1|root,COG3829@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes,4HVBX@91061|Bacilli,1ZS41@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MHYT,PAS_9
TLS3_k127_3174430_9	1123057.P872_16740	2.737e-24	105.0	COG1359@1|root,COG1359@2|Bacteria,4NSV0@976|Bacteroidetes,47R4E@768503|Cytophagia	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
TLS3_k127_3174430_6	1237149.C900_02698	1.081e-96	322.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,47PDG@768503|Cytophagia	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	fjo14	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
TLS3_k127_3174430_3	313606.M23134_07682	2.032e-141	454.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,47JUG@768503|Cytophagia	976|Bacteroidetes	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
TLS3_k127_3174430_2	1237149.C900_01609	4.126e-151	502.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,47K9X@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
TLS3_k127_3174430_5	1237149.C900_01608	6.046e-99	329.0	COG1024@1|root,COG1024@2|Bacteria,4NI32@976|Bacteroidetes,47MCZ@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
TLS3_k127_3174430_0	1237149.C900_01606	1.447e-236	747.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,47M73@768503|Cytophagia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
TLS3_k127_3174430_7	153721.MYP_4660	4.365e-55	201.0	COG1434@1|root,COG1434@2|Bacteria,4NNUT@976|Bacteroidetes,47QTX@768503|Cytophagia	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
TLS3_k127_3174430_8	1492737.FEM08_07130	3.633e-31	132.0	COG2067@1|root,COG2067@2|Bacteria,4NXNU@976|Bacteroidetes,1IACV@117743|Flavobacteriia,2NV66@237|Flavobacterium	976|Bacteroidetes	I	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
TLS3_k127_3174430_1	1237149.C900_04019	2.363e-181	582.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,47JTP@768503|Cytophagia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
TLS3_k127_3174430_4	1237149.C900_04021	2.598e-118	387.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,47N7V@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
TLS3_k127_3175238_0	471854.Dfer_4413	4.118e-199	629.0	COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,47M2I@768503|Cytophagia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
TLS3_k127_3175238_2	1487953.JMKF01000076_gene4046	3.618e-76	264.0	COG1209@1|root,COG1209@2|Bacteria,1G0RG@1117|Cyanobacteria,1HEHK@1150|Oscillatoriales	1117|Cyanobacteria	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
TLS3_k127_3175238_4	368407.Memar_2196	1.194e-25	115.0	arCOG06881@1|root,arCOG06881@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3175238_5	335283.Neut_0841	6.917e-05	55.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VIXC@28216|Betaproteobacteria,374P0@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the peptidase S8 family	mprA	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
TLS3_k127_3175238_3	743722.Sph21_5079	2.969e-27	114.0	2EUGE@1|root,33MYP@2|Bacteria,4NZG4@976|Bacteroidetes,1IYPX@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3175238_1	388413.ALPR1_19733	2.37e-96	334.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47Y44@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_3181264_1	1107311.Q767_12010	2.348e-24	117.0	COG1752@1|root,COG1752@2|Bacteria,4NUHF@976|Bacteroidetes,1HXTH@117743|Flavobacteriia	976|Bacteroidetes	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
TLS3_k127_3181264_0	1197477.IA57_00700	1.182e-63	221.0	COG0432@1|root,COG0432@2|Bacteria,4NNMN@976|Bacteroidetes,1I21B@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterised protein family UPF0047	yjbQ	-	-	-	-	-	-	-	-	-	-	-	UPF0047
TLS3_k127_3181264_2	1121287.AUMU01000006_gene3777	0.0009976	49.0	2E4ZV@1|root,32ZTG@2|Bacteria,4NWXA@976|Bacteroidetes,1IMJ8@117743|Flavobacteriia,3ZS4B@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3182020_4	468059.AUHA01000003_gene1460	8.266e-19	86.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1INWV@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
TLS3_k127_3182020_2	1124780.ANNU01000016_gene1821	5.142e-61	224.0	COG0729@1|root,COG0729@2|Bacteria,4NMUN@976|Bacteroidetes,47Y2C@768503|Cytophagia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
TLS3_k127_3182020_1	1237149.C900_02769	3.821e-178	563.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,47KB2@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
TLS3_k127_3182020_0	1237149.C900_02768	3.936e-199	631.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,47JE1@768503|Cytophagia	976|Bacteroidetes	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
TLS3_k127_3182020_5	1166018.FAES_0636	1.585e-16	80.0	2A7GX@1|root,30WEH@2|Bacteria,4P9UT@976|Bacteroidetes,47S3Y@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3182020_3	313606.M23134_00488	5.788e-55	194.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,47JAQ@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
TLS3_k127_3189595_1	1123248.KB893338_gene2306	1.118e-123	418.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IRGG@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_3189595_0	760192.Halhy_3653	1.24e-124	408.0	COG3828@1|root,COG3828@2|Bacteria,4NFMU@976|Bacteroidetes	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
TLS3_k127_3189595_4	468059.AUHA01000004_gene2375	7.515e-27	110.0	2BXBG@1|root,33WQF@2|Bacteria,4P3CB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3189595_2	324925.Ppha_2828	3.268e-106	351.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
TLS3_k127_3189595_3	616991.JPOO01000003_gene2483	2.372e-90	302.0	COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,1I031@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
TLS3_k127_3190132_2	1237149.C900_02609	3.188e-60	214.0	COG0156@1|root,COG0156@2|Bacteria,4NEXI@976|Bacteroidetes,47MTG@768503|Cytophagia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_3190132_1	643867.Ftrac_1013	3.078e-73	251.0	COG0132@1|root,COG0132@2|Bacteria,4NGKI@976|Bacteroidetes,47Q2B@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
TLS3_k127_3190132_0	1237149.C900_02607	8.348e-187	591.0	COG0161@1|root,COG0161@2|Bacteria,4NEJN@976|Bacteroidetes,47KV0@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,BATS,Radical_SAM
TLS3_k127_3190719_0	1237149.C900_04704	0.0	1247.0	COG4797@1|root,COG4797@2|Bacteria,4PKQS@976|Bacteroidetes,47K4H@768503|Cytophagia	976|Bacteroidetes	D	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
TLS3_k127_3190719_2	1237149.C900_04705	7.493e-71	244.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,47N8D@768503|Cytophagia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
TLS3_k127_3190719_1	1124780.ANNU01000028_gene1002	4.683e-72	245.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,47JSR@768503|Cytophagia	976|Bacteroidetes	C	Phosphate acetyl butaryl transferase	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
TLS3_k127_3215143_5	1124780.ANNU01000028_gene1007	4.307e-30	124.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_3215143_2	1124780.ANNU01000013_gene3805	1.448e-114	376.0	COG1752@1|root,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,47PF1@768503|Cytophagia	976|Bacteroidetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
TLS3_k127_3215143_4	1189612.A33Q_1076	4.092e-91	305.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,47N62@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_3215143_3	1239962.C943_01953	1.737e-95	323.0	COG2972@1|root,COG2972@2|Bacteria,4NRRA@976|Bacteroidetes,47V23@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_3215143_6	504472.Slin_2712	2.745e-17	85.0	2EU22@1|root,33MJ4@2|Bacteria,4NZM7@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3215143_0	1123503.KB908056_gene1846	1.332e-149	494.0	COG1409@1|root,COG1409@2|Bacteria,1NS3S@1224|Proteobacteria,2UI1P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
TLS3_k127_3215143_1	1121007.AUML01000017_gene399	1.152e-120	398.0	COG0696@1|root,COG0696@2|Bacteria,4PNG1@976|Bacteroidetes,1IKG8@117743|Flavobacteriia,2YHZ8@290174|Aquimarina	976|Bacteroidetes	G	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme,Phosphodiest
TLS3_k127_3216827_1	1123278.KB893389_gene4188	3.14e-210	666.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47YE9@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
TLS3_k127_3216827_2	761193.Runsl_2531	8.171e-157	508.0	COG3193@1|root,COG3193@2|Bacteria,4NGTI@976|Bacteroidetes,47TSK@768503|Cytophagia	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_3216827_3	1123277.KB893172_gene846	9.57e-54	198.0	2CE3R@1|root,33DMZ@2|Bacteria,4NZHH@976|Bacteroidetes,47UN3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3216827_5	1123277.KB893172_gene847	1.959e-18	91.0	2F8BT@1|root,340QV@2|Bacteria,4P400@976|Bacteroidetes,47VM1@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3216827_0	504472.Slin_4218	1.773e-230	737.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47NXA@768503|Cytophagia	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Cleaved_Adhesin,PKD,Peptidase_M43,fn3
TLS3_k127_3216827_4	929562.Emtol_2784	2.548e-50	182.0	COG0251@1|root,COG0251@2|Bacteria,4NPT2@976|Bacteroidetes,47QK8@768503|Cytophagia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Ribonuc_L-PSP
TLS3_k127_3218314_2	700598.Niako_7250	3.71e-31	125.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1IP1X@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
TLS3_k127_3218314_1	1408433.JHXV01000015_gene1803	1.476e-57	216.0	COG0330@1|root,COG0330@2|Bacteria,4NHJA@976|Bacteroidetes,1HZ37@117743|Flavobacteriia	976|Bacteroidetes	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TLS3_k127_3218314_0	1123248.KB893318_gene4139	1.945e-119	389.0	2BZ6M@1|root,2Z7HW@2|Bacteria,4NJ7B@976|Bacteroidetes,1IXEI@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_3218314_3	1124780.ANNU01000044_gene502	1.723e-09	62.0	COG0642@1|root,COG2905@1|root,COG2205@2|Bacteria,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,cNMP_binding
TLS3_k127_3232221_0	700598.Niako_0547	7.519e-170	557.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1IR1H@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Aldehyde oxidase xanthine dehydrogenase, molybdopterin binding	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
TLS3_k127_3232221_2	1107311.Q767_13655	2.003e-22	99.0	29XQK@1|root,30JGA@2|Bacteria,4NNS6@976|Bacteroidetes,1IDCA@117743|Flavobacteriia,2NY06@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3241952_1	1408473.JHXO01000001_gene2529	1.474e-105	347.0	COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes,2FM3A@200643|Bacteroidia	976|Bacteroidetes	S	Glycosyltransferase, group 2 family protein	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
TLS3_k127_3241952_2	1121285.AUFK01000017_gene3163	3.683e-05	53.0	29EN2@1|root,301K0@2|Bacteria,4PJY4@976|Bacteroidetes,1IM0B@117743|Flavobacteriia,3ZTID@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3241952_0	1237149.C900_05673	7.187e-135	440.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,47KVD@768503|Cytophagia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
TLS3_k127_3241952_3	28115.HR11_05150	0.0005446	45.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,2FN5Q@200643|Bacteroidia,22WI7@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
TLS3_k127_3247465_1	925409.KI911562_gene176	4.701e-116	379.0	COG1028@1|root,COG1028@2|Bacteria,4NH1Y@976|Bacteroidetes,1ISQU@117747|Sphingobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
TLS3_k127_3247465_0	1519464.HY22_05320	0.0	1299.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	-	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH,Glyco_hydro_63
TLS3_k127_3247465_2	945713.IALB_1958	3.043e-49	181.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	glgX	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
TLS3_k127_325051_5	394503.Ccel_3233	1.867e-12	73.0	COG2020@1|root,COG2020@2|Bacteria,1V3IZ@1239|Firmicutes,24FW3@186801|Clostridia,36M26@31979|Clostridiaceae	186801|Clostridia	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF218,PEMT
TLS3_k127_325051_0	641524.ADICYQ_4144	1.282e-304	948.0	COG0475@1|root,COG0475@2|Bacteria,4NF11@976|Bacteroidetes,47KD1@768503|Cytophagia	976|Bacteroidetes	P	Sodium/hydrogen exchanger family	ybaL_1	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
TLS3_k127_325051_6	992406.RIA_0072	1.52e-06	50.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,1HWQK@117743|Flavobacteriia	976|Bacteroidetes	L	TIGRFAM TIGR02757 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
TLS3_k127_325051_4	865937.Gilli_2611	6.332e-45	169.0	2E6C6@1|root,330ZZ@2|Bacteria,4NXMT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_325051_3	1121898.Q766_13115	2.704e-122	398.0	COG2326@1|root,COG2326@2|Bacteria,4NFJ5@976|Bacteroidetes,1HWS5@117743|Flavobacteriia,2NSVT@237|Flavobacterium	976|Bacteroidetes	S	nucleotide phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
TLS3_k127_325051_2	1094980.Mpsy_0697	1.279e-125	410.0	COG1105@1|root,arCOG00015@2157|Archaea,2XVPW@28890|Euryarchaeota,2NAXY@224756|Methanomicrobia	224756|Methanomicrobia	G	Phosphomethylpyrimidine kinase	-	-	2.7.1.11	ko:K16370	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
TLS3_k127_325051_1	1094980.Mpsy_0698	2.394e-274	853.0	COG0058@1|root,arCOG01421@2157|Archaea,2XV8J@28890|Euryarchaeota,2NACZ@224756|Methanomicrobia	224756|Methanomicrobia	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
TLS3_k127_325051_7	1121012.AUKX01000049_gene2623	1.359e-05	48.0	COG0589@1|root,COG0589@2|Bacteria,4PEZ0@976|Bacteroidetes,1IFJ9@117743|Flavobacteriia,23I96@178469|Arenibacter	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_3263501_5	313606.M23134_07564	1.146e-22	104.0	COG2834@1|root,COG2834@2|Bacteria,4NHV3@976|Bacteroidetes,47RIH@768503|Cytophagia	976|Bacteroidetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292,LolA_like
TLS3_k127_3263501_4	886379.AEWI01000022_gene100	1.804e-53	198.0	COG2992@1|root,COG2992@2|Bacteria,4PJ3P@976|Bacteroidetes,2G24A@200643|Bacteroidia,3XKJA@558415|Marinilabiliaceae	976|Bacteroidetes	S	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase
TLS3_k127_3263501_1	1237149.C900_01351	1.212e-96	327.0	COG0726@1|root,COG0726@2|Bacteria,4NXPA@976|Bacteroidetes,47XNH@768503|Cytophagia	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	3.5.1.41	ko:K01452	ko00520,ko01100,map00520,map01100	-	R02333	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Polysacc_deac_1
TLS3_k127_3263501_2	269798.CHU_0962	9.856e-62	216.0	COG1278@1|root,COG1278@2|Bacteria,4NNNH@976|Bacteroidetes,47QKE@768503|Cytophagia	976|Bacteroidetes	K	Cold shock protein domain	cspG	-	-	-	-	-	-	-	-	-	-	-	CSD
TLS3_k127_3263501_0	1122179.KB890420_gene2472	7.094e-188	600.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,1IQ0R@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TLS3_k127_3263501_3	991.IW20_12725	2.324e-61	215.0	COG3832@1|root,COG3832@2|Bacteria,4NT4P@976|Bacteroidetes,1IMWY@117743|Flavobacteriia,2NVXJ@237|Flavobacterium	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_3263501_6	643867.Ftrac_1599	1.328e-11	65.0	2BV0E@1|root,32QD0@2|Bacteria,4PBZ5@976|Bacteroidetes,47WJJ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3263501_7	1117318.PRUB_20564	8.035e-05	51.0	2EBHR@1|root,32TFF@2|Bacteria,1R3P0@1224|Proteobacteria,1S9WH@1236|Gammaproteobacteria,2Q34D@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3280206_1	1123057.P872_01145	2.173e-74	258.0	COG1555@1|root,COG1555@2|Bacteria,4NE88@976|Bacteroidetes,47KA3@768503|Cytophagia	976|Bacteroidetes	L	Helix-hairpin-helix motif	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
TLS3_k127_3280206_2	643867.Ftrac_2941	3.897e-58	210.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
TLS3_k127_3280206_3	761193.Runsl_4993	1.2e-35	139.0	COG0724@1|root,COG0724@2|Bacteria,4NT1J@976|Bacteroidetes,47RES@768503|Cytophagia	976|Bacteroidetes	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
TLS3_k127_3280206_4	1239962.C943_01761	4.996e-35	139.0	COG2259@1|root,COG2259@2|Bacteria,4NP94@976|Bacteroidetes,47W87@768503|Cytophagia	976|Bacteroidetes	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
TLS3_k127_3280206_0	1150600.ADIARSV_1327	4.987e-159	515.0	COG1070@1|root,COG1070@2|Bacteria,4NFBG@976|Bacteroidetes,1IPCF@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the FGGY kinase family	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
TLS3_k127_3283607_1	1227739.Hsw_4234	7.988e-174	555.0	COG0306@1|root,COG0306@2|Bacteria,4NE7J@976|Bacteroidetes,47KEG@768503|Cytophagia	976|Bacteroidetes	P	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
TLS3_k127_3283607_3	1185876.BN8_03255	9.835e-36	140.0	COG0745@1|root,COG0745@2|Bacteria,4NXE8@976|Bacteroidetes,47RYQ@768503|Cytophagia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_3283607_0	485918.Cpin_7206	2.088e-276	891.0	COG1352@1|root,COG2201@1|root,COG2202@1|root,COG3290@1|root,COG4251@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2202@2|Bacteria,COG3290@2|Bacteria,COG4251@2|Bacteria,4NE3J@976|Bacteroidetes,1J0JD@117747|Sphingobacteriia	976|Bacteroidetes	T	SMART MCP methyltransferase, CheR-type	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_9
TLS3_k127_3283607_2	1336803.PHEL49_2496	2.952e-123	413.0	COG1361@1|root,COG2373@1|root,COG3209@1|root,COG3291@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	inlJ	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,DUF11,DUF5011,FctA,Gram_pos_anchor,MucBP,VWA_2
TLS3_k127_3283869_3	1296415.JACC01000038_gene1898	0.0001938	48.0	2CYW5@1|root,32T50@2|Bacteria,4NS73@976|Bacteroidetes,1I3WS@117743|Flavobacteriia,2YJE5@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3283869_0	1237149.C900_02142	3.34e-106	355.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,47NU0@768503|Cytophagia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS3_k127_3283869_1	572479.Hprae_1442	5.497e-29	129.0	COG2989@1|root,COG2989@2|Bacteria,1VU2X@1239|Firmicutes,24Y29@186801|Clostridia,3WBGT@53433|Halanaerobiales	186801|Clostridia	S	Peptidoglycan-binding domain 1 protein	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
TLS3_k127_3284334_0	1237149.C900_02790	2.548e-300	931.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,47M2N@768503|Cytophagia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
TLS3_k127_3284334_3	1237149.C900_02791	1.527e-45	168.0	COG2332@1|root,COG2332@2|Bacteria,4NN85@976|Bacteroidetes,47PIE@768503|Cytophagia	976|Bacteroidetes	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
TLS3_k127_3284334_5	1150600.ADIARSV_3042	5.079e-12	68.0	2BZQ6@1|root,339SI@2|Bacteria,4NXJG@976|Bacteroidetes,1IUFA@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3284334_1	1237149.C900_02793	8.387e-96	317.0	COG0755@1|root,COG0755@2|Bacteria,4NFUS@976|Bacteroidetes,47MYQ@768503|Cytophagia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
TLS3_k127_3284334_2	866536.Belba_0720	2.72e-70	245.0	COG2386@1|root,COG2386@2|Bacteria,4NFQV@976|Bacteroidetes,47K0P@768503|Cytophagia	976|Bacteroidetes	O	ABC-type transport system involved in cytochrome c biogenesis permease component	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
TLS3_k127_3284334_4	1237149.C900_02795	2.641e-23	108.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	AAA_31,Wzz
TLS3_k127_3316784_0	1408813.AYMG01000017_gene5626	3.415e-251	778.0	COG0312@1|root,COG0312@2|Bacteria,4NG2Y@976|Bacteroidetes	976|Bacteroidetes	S	Peptidase U62 modulator of DNA gyrase	tldD1	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
TLS3_k127_3316784_1	1358423.N180_02330	1.365e-223	699.0	COG0312@1|root,COG0312@2|Bacteria,4NE1F@976|Bacteroidetes,1IPHR@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
TLS3_k127_3329942_3	1123277.KB893172_gene703	6.353e-112	370.0	COG0327@1|root,COG0327@2|Bacteria,4NFJ3@976|Bacteroidetes,47NXF@768503|Cytophagia	976|Bacteroidetes	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
TLS3_k127_3329942_1	761193.Runsl_2755	1.684e-140	450.0	COG0627@1|root,COG0627@2|Bacteria,4NGI8@976|Bacteroidetes,47M5Z@768503|Cytophagia	976|Bacteroidetes	S	Putative esterase	xynZ	-	-	-	-	-	-	-	-	-	-	-	Esterase
TLS3_k127_3329942_0	1123057.P872_03595	3.196e-212	668.0	COG0513@1|root,COG0513@2|Bacteria,4NE4Z@976|Bacteroidetes,47KF0@768503|Cytophagia	976|Bacteroidetes	L	DEAD DEAH box helicase	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
TLS3_k127_3329942_2	316067.Geob_3736	2.299e-128	415.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,42P7D@68525|delta/epsilon subdivisions,2WJ6S@28221|Deltaproteobacteria,43UZT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,DZR,SHOCT
TLS3_k127_3330096_2	926562.Oweho_2064	1.059e-75	258.0	COG0745@1|root,COG0745@2|Bacteria,4NE77@976|Bacteroidetes,1IMIZ@117743|Flavobacteriia	976|Bacteroidetes	T	transcriptional regulator	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_3330096_0	926562.Oweho_2065	2.246e-161	520.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,4NEIS@976|Bacteroidetes,1HXGB@117743|Flavobacteriia,2PBKD@246874|Cryomorphaceae	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	arlS_1	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_3330096_4	1237149.C900_02476	9.023e-21	103.0	COG3074@1|root,COG3074@2|Bacteria,4NQ7C@976|Bacteroidetes,47QDI@768503|Cytophagia	976|Bacteroidetes	D	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3330096_1	643867.Ftrac_1780	4.16e-85	288.0	COG2267@1|root,COG2267@2|Bacteria,4NF80@976|Bacteroidetes,47KEX@768503|Cytophagia	976|Bacteroidetes	I	alpha/beta hydrolase fold	pcbD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_3330096_3	1123401.JHYQ01000021_gene1060	2.9e-29	131.0	COG1520@1|root,COG1520@2|Bacteria,1R4I1@1224|Proteobacteria,1SJ0B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3369266_0	1237149.C900_01779	5.097e-220	687.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,47KFI@768503|Cytophagia	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
TLS3_k127_3369266_1	1237149.C900_01778	2.534e-35	139.0	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,47R9C@768503|Cytophagia	976|Bacteroidetes	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
TLS3_k127_3369678_1	1317122.ATO12_23895	1.177e-168	540.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1HX0V@117743|Flavobacteriia,2YH52@290174|Aquimarina	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_3369678_0	1317122.ATO12_23900	2.04e-266	844.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1HX0V@117743|Flavobacteriia,2YH7D@290174|Aquimarina	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_3369709_2	1120965.AUBV01000007_gene2701	1.572e-39	149.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,47JRR@768503|Cytophagia	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
TLS3_k127_3369709_0	1341181.FLJC2902T_03730	9.053e-250	785.0	COG0589@1|root,COG1914@1|root,COG0589@2|Bacteria,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,1HXXF@117743|Flavobacteriia,2NTC3@237|Flavobacterium	976|Bacteroidetes	PT	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp,Usp
TLS3_k127_3369709_1	1237149.C900_05811	1.143e-75	259.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,47JSQ@768503|Cytophagia	976|Bacteroidetes	K	Iron dependent repressor, metal binding and dimerisation domain	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
TLS3_k127_3369709_3	153721.MYP_4038	3.781e-33	133.0	COG0438@1|root,COG0438@2|Bacteria,4NMMT@976|Bacteroidetes,47PDF@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
TLS3_k127_3369718_0	1279009.ADICEAN_00022	4.804e-119	396.0	COG0739@1|root,COG0739@2|Bacteria,4NEBZ@976|Bacteroidetes,47JJ1@768503|Cytophagia	976|Bacteroidetes	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3,SH3_4
TLS3_k127_3369718_1	1150600.ADIARSV_4012	3.71e-36	144.0	COG1633@1|root,COG1633@2|Bacteria,4NNYT@976|Bacteroidetes,1ISK7@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF2383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2383
TLS3_k127_3369718_2	1279009.ADICEAN_00957	4.539e-34	141.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,47PDZ@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA,PD40
TLS3_k127_3369718_3	714943.Mucpa_5840	5.247e-33	130.0	COG0484@1|root,COG0484@2|Bacteria,4NME2@976|Bacteroidetes,1ISAR@117747|Sphingobacteriia	976|Bacteroidetes	O	KTSC domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,KTSC
TLS3_k127_3387869_1	926549.KI421517_gene3362	2.625e-109	361.0	COG0115@1|root,COG0115@2|Bacteria,4PJ29@976|Bacteroidetes,47M6P@768503|Cytophagia	976|Bacteroidetes	EH	PFAM Aminotransferase, class IV	-	-	2.6.1.21,2.6.1.42	ko:K00824,ko:K00826	ko00270,ko00280,ko00290,ko00310,ko00330,ko00360,ko00472,ko00473,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00310,map00330,map00360,map00472,map00473,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01148,R01214,R01582,R02199,R02459,R02851,R02924,R05053,R10991	RC00006,RC00008,RC00025,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_3387869_2	264462.Bd3651	1.461e-29	122.0	2DHH9@1|root,2ZZRU@2|Bacteria,1NIVT@1224|Proteobacteria,42X9Y@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
TLS3_k127_3387869_0	694427.Palpr_2652	2.659e-148	476.0	COG1902@1|root,COG1902@2|Bacteria,4NF98@976|Bacteroidetes,2FNNA@200643|Bacteroidia,22W6P@171551|Porphyromonadaceae	976|Bacteroidetes	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
TLS3_k127_3388257_1	1237149.C900_04994	2.276e-231	720.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,47KJE@768503|Cytophagia	976|Bacteroidetes	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
TLS3_k127_3388257_4	926549.KI421517_gene1436	3.867e-37	149.0	2E4RS@1|root,32ZKA@2|Bacteria,4NVN5@976|Bacteroidetes,47RDU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3388257_0	1185876.BN8_00257	0.0	1167.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47K68@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_3388257_2	1185876.BN8_00258	2.462e-84	293.0	28I8D@1|root,2Z8B7@2|Bacteria,4NM23@976|Bacteroidetes,47NIB@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
TLS3_k127_3388257_3	1185876.BN8_00259	8.03e-45	168.0	COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,47M8I@768503|Cytophagia	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3389240_2	1122621.ATZA01000001_gene1931	2.462e-10	61.0	COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,1INYG@117747|Sphingobacteriia	976|Bacteroidetes	IQ	PFAM GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
TLS3_k127_3389240_1	1279009.ADICEAN_01942	2.56e-125	405.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,47KI2@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
TLS3_k127_3389240_0	153721.MYP_4405	9.711e-210	665.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,47MAC@768503|Cytophagia	976|Bacteroidetes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
TLS3_k127_3401717_0	1237149.C900_04407	1.213e-275	865.0	COG1752@1|root,COG1752@2|Bacteria,4NF97@976|Bacteroidetes,47KND@768503|Cytophagia	976|Bacteroidetes	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
TLS3_k127_3401717_1	1237149.C900_00286	3.113e-56	207.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,47KES@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
TLS3_k127_3420632_5	504472.Slin_0288	2.034e-12	72.0	COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,47Q5N@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
TLS3_k127_3420632_1	760192.Halhy_0905	1.3e-97	333.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1INWP@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	3.5.2.6	ko:K01467	ko01501,ko02020,map01501,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase
TLS3_k127_3420632_2	929703.KE386491_gene4244	6.35e-95	316.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,47KTY@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
TLS3_k127_3420632_4	1189612.A33Q_1767	5.66e-28	114.0	COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,47R98@768503|Cytophagia	976|Bacteroidetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
TLS3_k127_3420632_0	1237149.C900_04984	2.842e-126	411.0	28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,47JAX@768503|Cytophagia	976|Bacteroidetes	S	S1 P1 nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease,Zn_dep_PLPC
TLS3_k127_3420632_3	1121904.ARBP01000001_gene5999	3.075e-32	128.0	2C4KB@1|root,32YM4@2|Bacteria,4NUZU@976|Bacteroidetes,47RBT@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3426857_0	485918.Cpin_6494	4.664e-76	264.0	COG0266@1|root,COG0266@2|Bacteria,4NFM2@976|Bacteroidetes,1IS7F@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA glycosylase AP lyase, H2TH DNA-binding	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH
TLS3_k127_3426857_1	926559.JoomaDRAFT_3067	4.275e-66	229.0	COG1247@1|root,COG1247@2|Bacteria,4NNVF@976|Bacteroidetes,1I5B6@117743|Flavobacteriia	976|Bacteroidetes	M	phosphinothricin acetyltransferase	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_4
TLS3_k127_3426857_2	388413.ALPR1_16718	2.461e-64	224.0	COG0262@1|root,COG0262@2|Bacteria,4NM92@976|Bacteroidetes,47QQZ@768503|Cytophagia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
TLS3_k127_3434714_2	1237149.C900_01163	2.499e-64	230.0	COG1506@1|root,COG1506@2|Bacteria,4NGW1@976|Bacteroidetes,47MCA@768503|Cytophagia	976|Bacteroidetes	E	Secretory lipase	-	-	-	-	-	-	-	-	-	-	-	-	LIP,Peptidase_S9
TLS3_k127_3434714_1	1279009.ADICEAN_01724	2.201e-67	237.0	28HQQ@1|root,2Z7YB@2|Bacteria,4NJCY@976|Bacteroidetes,47QT8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3434714_0	1237149.C900_02767	1.131e-146	469.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,47JAQ@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
TLS3_k127_3449710_0	1237149.C900_00613	9.763e-162	513.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,47JQN@768503|Cytophagia	976|Bacteroidetes	G	PFAM Transketolase, C-terminal domain	dxs	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
TLS3_k127_3449710_1	313606.M23134_07479	6.77e-92	315.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47MEM@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
TLS3_k127_3452094_3	1121904.ARBP01000006_gene4002	8.695e-08	57.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,47KGU@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
TLS3_k127_3452094_0	929556.Solca_1727	0.0	1455.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IQYT@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS3_k127_3452094_2	929556.Solca_1726	1.17e-107	361.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IP8S@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
TLS3_k127_3452094_1	1121373.KB903643_gene3408	1.006e-113	383.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,47KE9@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_3469634_1	172045.KS04_07205	4.554e-23	109.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
TLS3_k127_3469634_0	880071.Fleli_0020	1.003e-70	255.0	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,4NI5R@976|Bacteroidetes,47XFE@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_3469634_2	1454007.JAUG01000029_gene3241	0.0002383	48.0	COG0457@1|root,COG0457@2|Bacteria,4NIKS@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_8
TLS3_k127_3480124_0	1237149.C900_00480	2.732e-278	877.0	COG1409@1|root,COG4775@1|root,COG1409@2|Bacteria,COG4775@2|Bacteria,4NF9N@976|Bacteroidetes,47JAP@768503|Cytophagia	976|Bacteroidetes	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Metallophos
TLS3_k127_3480124_1	1408433.JHXV01000014_gene3680	1.477e-33	138.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1IG7B@117743|Flavobacteriia,2PBE8@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_3482326_0	926566.Terro_1697	8.725e-45	174.0	COG0666@1|root,COG0666@2|Bacteria,3Y6WC@57723|Acidobacteria	57723|Acidobacteria	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
TLS3_k127_3482326_4	1449050.JNLE01000003_gene3593	3.487e-08	59.0	COG0346@1|root,COG0346@2|Bacteria,1VVX9@1239|Firmicutes,254DW@186801|Clostridia	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_3482326_2	1300345.LF41_2483	1.099e-15	81.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_3482326_1	1396141.BATP01000023_gene548	3.342e-38	151.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_5
TLS3_k127_3482326_3	1123248.KB893319_gene4016	2.015e-13	70.0	COG2764@1|root,COG2764@2|Bacteria,4P63R@976|Bacteroidetes	976|Bacteroidetes	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3483864_0	269798.CHU_3660	3.135e-196	633.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NKC3@976|Bacteroidetes,47NP5@768503|Cytophagia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
TLS3_k127_3498197_9	760192.Halhy_2129	7.974e-10	59.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPFZ@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
TLS3_k127_3498197_10	313595.P700755_001026	0.0004631	45.0	COG1404@1|root,COG1404@2|Bacteria,4PM4C@976|Bacteroidetes,1IJJ4@117743|Flavobacteriia,4C2F9@83612|Psychroflexus	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_3498197_5	1144313.PMI10_04317	2.487e-81	280.0	COG2207@1|root,COG2207@2|Bacteria,4NF63@976|Bacteroidetes,1HZAQ@117743|Flavobacteriia,2NU4P@237|Flavobacterium	976|Bacteroidetes	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18,HTH_AraC
TLS3_k127_3498197_6	485918.Cpin_4896	5.349e-75	259.0	COG1028@1|root,COG1028@2|Bacteria,4NF7M@976|Bacteroidetes,1IXJ0@117747|Sphingobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_3498197_3	616991.JPOO01000001_gene2926	1.084e-97	325.0	COG0491@1|root,COG0491@2|Bacteria,4NPPW@976|Bacteroidetes,1I1N1@117743|Flavobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	ccrA	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
TLS3_k127_3498197_2	700598.Niako_2665	1.464e-109	362.0	COG1235@1|root,COG1235@2|Bacteria,4NDVI@976|Bacteroidetes,1IR6D@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I	vicX	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
TLS3_k127_3498197_0	269798.CHU_2572	5.564e-123	401.0	COG0492@1|root,COG0492@2|Bacteria,4NEC8@976|Bacteroidetes,47MC4@768503|Cytophagia	976|Bacteroidetes	O	Pyridine nucleotide-disulphide oxidoreductase	ahpF	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
TLS3_k127_3498197_1	1121875.KB907547_gene3399	3.082e-115	377.0	COG1082@1|root,COG1082@2|Bacteria,4NM4N@976|Bacteroidetes	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_3498197_7	1122947.FR7_0764	5.778e-59	211.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_3498197_8	1048983.EL17_05960	1.394e-45	172.0	COG2259@1|root,COG2259@2|Bacteria,4NK73@976|Bacteroidetes,47RXD@768503|Cytophagia	976|Bacteroidetes	S	Doxx family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3498197_4	760192.Halhy_0527	1.023e-84	284.0	COG3119@1|root,COG3292@1|root,COG3119@2|Bacteria,COG3292@2|Bacteria,4NI2T@976|Bacteroidetes,1IPBY@117747|Sphingobacteriia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop,YceI
TLS3_k127_3500168_7	1123248.KB893370_gene5031	1.322e-49	179.0	COG4941@1|root,COG4941@2|Bacteria,4NGCS@976|Bacteroidetes,1IRPG@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM RNA polymerase sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_3500168_0	926549.KI421517_gene3714	1.984e-189	600.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,47K1Q@768503|Cytophagia	976|Bacteroidetes	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_3500168_9	929704.Myrod_3492	1.6e-06	53.0	2DR2H@1|root,339W7@2|Bacteria,4NXRG@976|Bacteroidetes,1I6K3@117743|Flavobacteriia,47J4H@76831|Myroides	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3500168_3	926549.KI421517_gene1735	3.504e-94	312.0	28KW5@1|root,2ZACI@2|Bacteria,4P15K@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3500168_8	700598.Niako_7232	6.443e-28	120.0	2E32R@1|root,32Y2Y@2|Bacteria,4NVIY@976|Bacteroidetes,1IU4T@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3500168_6	760192.Halhy_5051	5.625e-51	195.0	COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,1IRNF@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_3500168_5	1123248.KB893334_gene2776	1.129e-57	210.0	COG3279@1|root,COG3279@2|Bacteria,4PI7R@976|Bacteroidetes,1IWN1@117747|Sphingobacteriia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_3500168_4	755732.Fluta_0493	1.115e-79	277.0	28IM1@1|root,2Z8MK@2|Bacteria,4NIZ0@976|Bacteroidetes,1HYU0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3500168_2	1121904.ARBP01000001_gene5494	2.141e-134	453.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,47KAN@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
TLS3_k127_3500168_1	929556.Solca_3824	1.898e-170	540.0	COG0520@1|root,COG0520@2|Bacteria,4NJ4E@976|Bacteroidetes,1IQHG@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
TLS3_k127_3501765_6	1122176.KB903555_gene3745	1.186e-23	101.0	COG0527@1|root,COG0527@2|Bacteria,4PKFA@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the aspartokinase family	-	-	1.1.1.3,2.7.2.4	ko:K00928,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
TLS3_k127_3501765_1	1189612.A33Q_4492	7.662e-220	694.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,47KEQ@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM Aspartate kinase	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
TLS3_k127_3501765_3	153721.MYP_1180	3.63e-121	396.0	COG0083@1|root,COG0083@2|Bacteria,4NE2M@976|Bacteroidetes,47KGY@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
TLS3_k127_3501765_2	153721.MYP_1181	2.658e-168	539.0	COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,47KUN@768503|Cytophagia	976|Bacteroidetes	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
TLS3_k127_3501765_5	1237149.C900_01201	1.185e-93	311.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,47P7V@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
TLS3_k127_3501765_0	1237149.C900_01564	1.025e-224	726.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,47JHF@768503|Cytophagia	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_8
TLS3_k127_3501765_4	1237149.C900_01565	5.069e-94	317.0	28MS7@1|root,2ZB0M@2|Bacteria,4NHCQ@976|Bacteroidetes,47JQ9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_351122_3	1237149.C900_01144	1.623e-118	386.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,47JX1@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_351122_4	313606.M23134_07960	4.978e-93	310.0	COG0564@1|root,COG0564@2|Bacteria,4NHKH@976|Bacteroidetes,47KJC@768503|Cytophagia	976|Bacteroidetes	J	TIGRFAM pseudouridine synthase, RluA family	-	-	5.4.99.23,5.4.99.24	ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
TLS3_k127_351122_5	1123057.P872_03785	3.196e-65	225.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,47PQ7@768503|Cytophagia	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
TLS3_k127_351122_6	866536.Belba_1874	5.909e-49	177.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,47Q9B@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
TLS3_k127_351122_1	1237149.C900_00092	3.308e-123	400.0	COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,47M3D@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
TLS3_k127_351122_2	1237149.C900_00090	1.019e-122	398.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,47M4X@768503|Cytophagia	976|Bacteroidetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
TLS3_k127_351122_0	1121904.ARBP01000053_gene476	2.695e-170	546.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47K4A@768503|Cytophagia	976|Bacteroidetes	C	PFAM Aldehyde dehydrogenase	sad	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_3514272_1	1237149.C900_03999	2.458e-104	357.0	COG0457@1|root,COG0457@2|Bacteria,4NGQ7@976|Bacteroidetes,47KHQ@768503|Cytophagia	976|Bacteroidetes	U	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
TLS3_k127_3514272_0	1121889.AUDM01000004_gene2494	2.399e-148	481.0	COG3004@1|root,COG3004@2|Bacteria,4NFC4@976|Bacteroidetes,1HXXZ@117743|Flavobacteriia,2NS9U@237|Flavobacterium	976|Bacteroidetes	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
TLS3_k127_3514272_3	1237149.C900_04000	1.906e-40	151.0	COG0721@1|root,COG0721@2|Bacteria,4NV0A@976|Bacteroidetes,47QCX@768503|Cytophagia	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
TLS3_k127_3514272_2	1237149.C900_04001	6.357e-73	250.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,47JI7@768503|Cytophagia	976|Bacteroidetes	I	TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TLS3_k127_35306_2	1185876.BN8_06574	2.811e-57	204.0	COG1595@1|root,COG1595@2|Bacteria,4NKHT@976|Bacteroidetes,47P68@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_35306_4	313606.M23134_07556	3.829e-30	136.0	COG3266@1|root,COG3266@2|Bacteria,4NKN6@976|Bacteroidetes,47NWQ@768503|Cytophagia	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
TLS3_k127_35306_3	926556.Echvi_2894	1.93e-48	179.0	COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes,47QHY@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_35306_1	1144313.PMI10_01192	1.952e-92	312.0	COG4315@1|root,COG4315@2|Bacteria,4NI3N@976|Bacteroidetes,1HYWK@117743|Flavobacteriia,2NU8W@237|Flavobacterium	976|Bacteroidetes	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
TLS3_k127_35306_0	761193.Runsl_1968	8.844e-279	877.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_3531067_1	1185876.BN8_01621	3.664e-100	331.0	COG0671@1|root,COG0671@2|Bacteria,4NKIN@976|Bacteroidetes,47T9W@768503|Cytophagia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
TLS3_k127_3531067_2	1185876.BN8_01620	1.91e-32	140.0	COG2207@1|root,COG2207@2|Bacteria,4NVK7@976|Bacteroidetes,47XDI@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_3531067_0	926549.KI421517_gene1083	2.858e-176	559.0	COG2272@1|root,COG2272@2|Bacteria,4NG5B@976|Bacteroidetes,47JGD@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
TLS3_k127_353942_7	1123248.KB893370_gene5061	1.759e-18	87.0	COG3842@1|root,COG3842@2|Bacteria,4NEZ6@976|Bacteroidetes,1IQV7@117747|Sphingobacteriia	976|Bacteroidetes	E	ABC transporter	fbpC2	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
TLS3_k127_353942_0	1123248.KB893325_gene1223	2.991e-235	739.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NIKG@976|Bacteroidetes,1IWUH@117747|Sphingobacteriia	976|Bacteroidetes	C	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH
TLS3_k127_353942_4	1210884.HG799464_gene10974	2.37e-39	150.0	COG1145@1|root,32SB1@2|Bacteria,2J183@203682|Planctomycetes	203682|Planctomycetes	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
TLS3_k127_353942_5	153721.MYP_4704	3.309e-38	153.0	COG3637@1|root,COG3637@2|Bacteria,4NS0N@976|Bacteroidetes,47T06@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
TLS3_k127_353942_6	1235813.JCM10003_2547	1.879e-23	108.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,2FNCU@200643|Bacteroidia,4AKZ6@815|Bacteroidaceae	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
TLS3_k127_353942_3	1121904.ARBP01000013_gene374	4.215e-125	405.0	COG0287@1|root,COG0287@2|Bacteria,4NGI9@976|Bacteroidetes,47JFK@768503|Cytophagia	976|Bacteroidetes	E	Phosphogluconate dehydrogenase (decarboxylating) C-term	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_2,PGDH_C
TLS3_k127_353942_2	1121904.ARBP01000013_gene375	1.216e-131	434.0	COG3395@1|root,COG3395@2|Bacteria,4NFF9@976|Bacteroidetes,47N65@768503|Cytophagia	976|Bacteroidetes	S	Putative nucleotide-binding of sugar-metabolising enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DUF1357_C,DUF1537
TLS3_k127_353942_1	1121904.ARBP01000013_gene376	6.829e-162	515.0	COG1850@1|root,COG1850@2|Bacteria,4NFRC@976|Bacteroidetes,47NXH@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the RuBisCO large chain family	-	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
TLS3_k127_35418_0	1249997.JHZW01000003_gene3209	0.0	1211.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Reg_prop,Y_Y_Y
TLS3_k127_35418_1	1249997.JHZW01000003_gene3212	2.814e-218	721.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Reg_prop,SnoaL_3,Y_Y_Y
TLS3_k127_35418_4	1249997.JHZW01000003_gene3213	4.977e-52	186.0	COG0745@1|root,COG0745@2|Bacteria,4NQ69@976|Bacteroidetes,1I32T@117743|Flavobacteriia,2PIMN@252356|Maribacter	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_35418_2	925409.KI911562_gene2742	7.26e-169	536.0	COG2114@1|root,COG2204@1|root,COG2114@2|Bacteria,COG2204@2|Bacteria,4NF1F@976|Bacteroidetes,1IPZU@117747|Sphingobacteriia	976|Bacteroidetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
TLS3_k127_35418_3	1237149.C900_05503	3.218e-89	299.0	28JIP@1|root,2Z82C@2|Bacteria,4NFN9@976|Bacteroidetes,47PJT@768503|Cytophagia	976|Bacteroidetes	S	S1 P1 nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease
TLS3_k127_3552545_2	443152.MDG893_14183	4.73e-22	96.0	2E8MC@1|root,328VW@2|Bacteria,1NQ0Y@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3552545_0	1341181.FLJC2902T_31920	7.54e-103	342.0	2CF7W@1|root,32VFG@2|Bacteria,4NUA7@976|Bacteroidetes,1I5GI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3552545_1	376686.Fjoh_3633	3.807e-61	215.0	2E0FH@1|root,32W1Q@2|Bacteria,4P974@976|Bacteroidetes,1IDJR@117743|Flavobacteriia,2NYMM@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_355390_1	1048983.EL17_22600	3.652e-36	137.0	COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,47R42@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TLS3_k127_355390_0	1089547.KB913013_gene4642	0.0	1062.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,47KTB@768503|Cytophagia	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
TLS3_k127_355390_2	1123057.P872_04335	2.062e-35	138.0	COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,47NSZ@768503|Cytophagia	976|Bacteroidetes	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
TLS3_k127_3554799_1	1189612.A33Q_2344	4.358e-61	214.0	COG3491@1|root,COG3491@2|Bacteria,4NED5@976|Bacteroidetes,47JDX@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
TLS3_k127_3554799_0	485917.Phep_0814	2.554e-101	335.0	COG0605@1|root,COG0605@2|Bacteria,4NK61@976|Bacteroidetes,1IRYF@117747|Sphingobacteriia	976|Bacteroidetes	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
TLS3_k127_3554799_2	1237149.C900_01035	1.357e-28	119.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,47K9Z@768503|Cytophagia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
TLS3_k127_356425_0	1121904.ARBP01000004_gene1108	7.577e-273	863.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_356425_1	1358423.N180_17580	5.92e-256	812.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia	976|Bacteroidetes	V	TIGRFAM Acidobacterial duplicated orphan permease	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_356425_2	1121904.ARBP01000004_gene1108	1.386e-239	758.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_3564428_2	700598.Niako_4265	2.189e-112	365.0	COG2207@1|root,COG2207@2|Bacteria,4NGWC@976|Bacteroidetes,1IR95@117747|Sphingobacteriia	976|Bacteroidetes	K	SMART helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_3564428_0	471854.Dfer_1514	1.288e-162	518.0	COG1028@1|root,COG1028@2|Bacteria,4NHSE@976|Bacteroidetes,47N8M@768503|Cytophagia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_3564428_1	714943.Mucpa_2156	3.448e-114	387.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IPB0@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_3580926_3	1341181.FLJC2902T_00880	3.356e-66	235.0	2C3WA@1|root,2Z8P1@2|Bacteria,4NW8R@976|Bacteroidetes,1IAW1@117743|Flavobacteriia,2NWKD@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3580926_4	929556.Solca_2785	1.757e-55	201.0	2C7HJ@1|root,31BFZ@2|Bacteria,4NRGQ@976|Bacteroidetes,1IXYY@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_3580926_5	1239962.C943_00992	4.306e-36	145.0	2C852@1|root,32YB2@2|Bacteria,4NM63@976|Bacteroidetes,47S6T@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
TLS3_k127_3580926_1	1239962.C943_01003	1.76e-191	608.0	COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,47KN4@768503|Cytophagia	976|Bacteroidetes	MU	TIGRFAM efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family	-	-	-	ko:K18139,ko:K18300	ko01501,ko02024,map01501,map02024	M00641,M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
TLS3_k127_3580926_0	1239962.C943_01002	0.0	1668.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47JGB@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
TLS3_k127_3580926_2	1239962.C943_01001	1.383e-145	471.0	COG0845@1|root,COG0845@2|Bacteria,4NIDC@976|Bacteroidetes,47M9U@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
TLS3_k127_358440_2	926549.KI421517_gene1245	1.761e-134	440.0	COG1538@1|root,COG1538@2|Bacteria,4NFEC@976|Bacteroidetes,47KYU@768503|Cytophagia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_358440_5	1124780.ANNU01000010_gene3664	5.007e-96	329.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,47NGP@768503|Cytophagia	976|Bacteroidetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_3,HlyD_D23
TLS3_k127_358440_3	1089547.KB913013_gene4446	4.292e-124	411.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,47K97@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
TLS3_k127_358440_7	385682.AFSL01000004_gene956	4.635e-40	156.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,2FMQN@200643|Bacteroidia,3XIS8@558415|Marinilabiliaceae	976|Bacteroidetes	M	Protein of unknown function (DUF3347)	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HMA,HlyD_D23
TLS3_k127_358440_0	761193.Runsl_5948	9.085e-163	526.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,47KSB@768503|Cytophagia	976|Bacteroidetes	Q	PFAM multicopper oxidase type 3	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
TLS3_k127_358440_6	880070.Cycma_4597	1.224e-47	176.0	COG0845@1|root,COG0845@2|Bacteria,4NRKU@976|Bacteroidetes	976|Bacteroidetes	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347
TLS3_k127_358440_8	1237149.C900_02494	1.523e-38	151.0	COG0526@1|root,COG0526@2|Bacteria,4NS1W@976|Bacteroidetes,47WNY@768503|Cytophagia	976|Bacteroidetes	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
TLS3_k127_358440_1	1237149.C900_02493	1.26e-137	448.0	COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,47JYZ@768503|Cytophagia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TLS3_k127_358440_4	1121373.KB903631_gene607	1.357e-118	400.0	COG2340@1|root,COG2340@2|Bacteria,4PC4Z@976|Bacteroidetes,47WU2@768503|Cytophagia	976|Bacteroidetes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
TLS3_k127_3589787_3	1185876.BN8_02100	1.704e-40	152.0	COG0730@1|root,COG0730@2|Bacteria,4PKBI@976|Bacteroidetes,47K77@768503|Cytophagia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_3589787_0	926549.KI421517_gene873	1.941e-168	539.0	COG2059@1|root,COG2059@2|Bacteria,4NNZ1@976|Bacteroidetes,47M3J@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
TLS3_k127_3589787_2	700598.Niako_5254	8.245e-52	187.0	COG2940@1|root,COG2940@2|Bacteria,4NQ3D@976|Bacteroidetes	976|Bacteroidetes	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
TLS3_k127_3589787_1	1237149.C900_03999	4.609e-70	250.0	COG0457@1|root,COG0457@2|Bacteria,4NGQ7@976|Bacteroidetes,47KHQ@768503|Cytophagia	976|Bacteroidetes	U	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
TLS3_k127_3601352_0	926562.Oweho_1034	7.342e-105	346.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
TLS3_k127_3601352_2	1121875.KB907547_gene2995	4.048e-68	239.0	COG2067@1|root,COG2067@2|Bacteria,4NX18@976|Bacteroidetes,1I5D9@117743|Flavobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3601352_3	1239962.C943_00133	8.692e-37	145.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	MA20_20735	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_3601352_4	187272.Mlg_2501	1.289e-12	73.0	COG3203@1|root,COG3203@2|Bacteria,1MX4Q@1224|Proteobacteria,1RY5B@1236|Gammaproteobacteria,1X0SM@135613|Chromatiales	135613|Chromatiales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3601749_0	196490.AUEZ01000058_gene1085	7.459e-232	741.0	COG0507@1|root,COG1112@1|root,COG2251@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,COG2251@2|Bacteria,1MWW9@1224|Proteobacteria,2TTSD@28211|Alphaproteobacteria,3JQNN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,RNase_H_2
TLS3_k127_3601749_1	1007103.AFHW01000017_gene5782	2.834e-56	199.0	COG3832@1|root,COG3832@2|Bacteria,1V799@1239|Firmicutes,4HHAD@91061|Bacilli,26WTI@186822|Paenibacillaceae	91061|Bacilli	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_3601749_3	616991.JPOO01000001_gene4165	5.247e-33	132.0	2AFVV@1|root,315YK@2|Bacteria,4NQ4S@976|Bacteroidetes,1I2VI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3601749_5	1492737.FEM08_35000	1.103e-15	79.0	2AF0Z@1|root,314Z9@2|Bacteria,4P7CF@976|Bacteroidetes,1IAXW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3601749_4	86416.Clopa_2105	1.156e-18	90.0	COG5646@1|root,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,24K4J@186801|Clostridia,36JND@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
TLS3_k127_3601749_2	743722.Sph21_5049	2.544e-54	193.0	COG2259@1|root,31TV8@2|Bacteria,4NQJ7@976|Bacteroidetes,1ISPT@117747|Sphingobacteriia	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
TLS3_k127_3608527_3	1237149.C900_00480	1.972e-108	366.0	COG1409@1|root,COG4775@1|root,COG1409@2|Bacteria,COG4775@2|Bacteria,4NF9N@976|Bacteroidetes,47JAP@768503|Cytophagia	976|Bacteroidetes	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Metallophos
TLS3_k127_3608527_1	1237149.C900_04487	7.447e-124	411.0	COG4339@1|root,COG4339@2|Bacteria,4PKIS@976|Bacteroidetes,47KP1@768503|Cytophagia	976|Bacteroidetes	S	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	HD
TLS3_k127_3608527_7	1237149.C900_03766	1.375e-43	166.0	2DVQJ@1|root,32UZZ@2|Bacteria,4P9HJ@976|Bacteroidetes,47RBJ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3608527_6	1237149.C900_00073	2.861e-44	168.0	COG0457@1|root,COG0457@2|Bacteria	1237149.C900_00073|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3608527_2	1237149.C900_00072	3.034e-113	371.0	COG1273@1|root,COG1273@2|Bacteria,4NHHQ@976|Bacteroidetes,47PE5@768503|Cytophagia	976|Bacteroidetes	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
TLS3_k127_3608527_0	1239962.C943_01898	7.507e-172	549.0	COG0661@1|root,COG0661@2|Bacteria,4NDUP@976|Bacteroidetes,47JE8@768503|Cytophagia	976|Bacteroidetes	S	unusual protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC1,APH
TLS3_k127_3608527_5	643867.Ftrac_1566	1.754e-64	227.0	28HM7@1|root,2Z7VU@2|Bacteria,4NGV1@976|Bacteroidetes,47PTW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3608527_4	1123057.P872_13775	4.014e-66	243.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,47JWQ@768503|Cytophagia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
TLS3_k127_362270_1	1121481.AUAS01000011_gene4969	4.075e-126	412.0	COG0296@1|root,COG0296@2|Bacteria,4PKT8@976|Bacteroidetes,47M5D@768503|Cytophagia	976|Bacteroidetes	G	SMART alpha amylase catalytic sub domain	-	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
TLS3_k127_362270_0	1123248.KB893325_gene1184	2.976e-274	866.0	COG3280@1|root,COG3280@2|Bacteria,4PM29@976|Bacteroidetes,1J0MJ@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	-	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
TLS3_k127_362936_7	1123248.KB893325_gene1155	2.105e-47	173.0	COG2334@1|root,COG2334@2|Bacteria,4NH00@976|Bacteroidetes,1INVB@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Aminoglycoside phosphotransferase	mdsC	-	-	-	-	-	-	-	-	-	-	-	APH
TLS3_k127_362936_2	760192.Halhy_5258	4.118e-152	488.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,1IX3R@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
TLS3_k127_362936_1	929713.NIASO_00660	9.937e-157	502.0	COG4299@1|root,COG4299@2|Bacteria,4NH8T@976|Bacteroidetes,1INPE@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
TLS3_k127_362936_0	926549.KI421517_gene286	1.174e-178	582.0	COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,47NCY@768503|Cytophagia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
TLS3_k127_362936_4	1121012.AUKX01000004_gene3469	2.1e-114	380.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,1HYFP@117743|Flavobacteriia,23GX1@178469|Arenibacter	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
TLS3_k127_362936_8	1237149.C900_01259	1.151e-21	102.0	28P8J@1|root,2ZC2G@2|Bacteria,4NTQZ@976|Bacteroidetes,47SAC@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_362936_3	1124780.ANNU01000030_gene1122	7.041e-116	378.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,47JXY@768503|Cytophagia	976|Bacteroidetes	G	Glycoside hydrolase family 16	bglA	-	3.2.1.73	ko:K01216	-	-	-	-	ko00000,ko01000	-	-	-	GDPD,Glyco_hydro_16
TLS3_k127_362936_5	1237149.C900_00393	7.599e-66	229.0	COG1595@1|root,COG1595@2|Bacteria,4NMYQ@976|Bacteroidetes,47PII@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_362936_6	1237149.C900_00392	2.167e-53	198.0	COG5343@1|root,COG5343@2|Bacteria,4PNQ9@976|Bacteroidetes,47YF0@768503|Cytophagia	976|Bacteroidetes	S	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
TLS3_k127_36304_1	1237149.C900_05943	1.053e-47	177.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,47JH7@768503|Cytophagia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
TLS3_k127_36304_0	1123248.KB893326_gene1402	3.756e-117	383.0	COG2755@1|root,COG2755@2|Bacteria,4NHV1@976|Bacteroidetes,1INN7@117747|Sphingobacteriia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS3_k127_36304_2	1123393.KB891316_gene1745	1.944e-45	176.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VHPI@28216|Betaproteobacteria	28216|Betaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9,dCache_1
TLS3_k127_36304_3	1479235.KK366039_gene145	4.076e-12	77.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XIJY@135619|Oceanospirillales	135619|Oceanospirillales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,EAL,GAF,GAF_2,GGDEF,PAS_9,Response_reg
TLS3_k127_3632192_1	1123057.P872_15110	1.09e-100	346.0	COG2067@1|root,COG2067@2|Bacteria,4NFS7@976|Bacteroidetes,47K28@768503|Cytophagia	976|Bacteroidetes	I	PFAM Outer membrane protein transport protein (OMPP1 FadL TodX)	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
TLS3_k127_3632192_2	1120968.AUBX01000009_gene118	4.792e-06	59.0	2CJG0@1|root,332HN@2|Bacteria,4NM27@976|Bacteroidetes,47M0N@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3632192_0	1121899.Q764_03595	1.208e-210	659.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,1HXK2@117743|Flavobacteriia,2NTJ3@237|Flavobacterium	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
TLS3_k127_365441_4	1237149.C900_04161	6.223e-86	287.0	COG1225@1|root,COG1225@2|Bacteria,4NSHI@976|Bacteroidetes,47RHQ@768503|Cytophagia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TLS3_k127_365441_5	1121129.KB903361_gene2998	1.342e-73	270.0	COG0312@1|root,COG0312@2|Bacteria,4P2UR@976|Bacteroidetes,2G330@200643|Bacteroidia	976|Bacteroidetes	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
TLS3_k127_365441_1	929713.NIASO_03930	5.902e-146	481.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
TLS3_k127_365441_2	1279009.ADICEAN_01221	1.977e-129	422.0	COG3268@1|root,COG3268@2|Bacteria,4NHDM@976|Bacteroidetes,47N4Y@768503|Cytophagia	976|Bacteroidetes	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
TLS3_k127_365441_7	1123057.P872_04630	3.608e-27	115.0	COG1393@1|root,COG1393@2|Bacteria,4NXD1@976|Bacteroidetes,47SWP@768503|Cytophagia	976|Bacteroidetes	P	ArsC family	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
TLS3_k127_365441_0	1121875.KB907551_gene1032	4.015e-219	692.0	COG2730@1|root,COG2730@2|Bacteria,4NJM9@976|Bacteroidetes	976|Bacteroidetes	G	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
TLS3_k127_365441_3	1239962.C943_03147	6.813e-118	385.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,47M0E@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
TLS3_k127_365441_6	1123248.KB893329_gene4462	1.707e-66	228.0	COG4993@1|root,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,1IQUR@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
TLS3_k127_3657035_7	929703.KE386491_gene2153	1.478e-09	66.0	2DGD5@1|root,2ZVH9@2|Bacteria,4NWG4@976|Bacteroidetes,47Y30@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3657035_1	1237149.C900_02623	1.008e-174	556.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,47JN4@768503|Cytophagia	976|Bacteroidetes	S	CinA-like protein	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
TLS3_k127_3657035_2	866536.Belba_3555	1.476e-174	557.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,47JDY@768503|Cytophagia	976|Bacteroidetes	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bfmBB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS3_k127_3657035_4	1237149.C900_02619	8.31e-83	280.0	COG1192@1|root,COG1192@2|Bacteria,4NPVF@976|Bacteroidetes,47PVS@768503|Cytophagia	976|Bacteroidetes	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	VirC1
TLS3_k127_3657035_0	1123057.P872_02395	9.852e-189	596.0	COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,47JY2@768503|Cytophagia	976|Bacteroidetes	E	PFAM Cys Met metabolism PLP-dependent enzyme	metC	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
TLS3_k127_3657035_3	714943.Mucpa_1441	1.367e-99	340.0	COG2911@1|root,COG3391@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,4NHHA@976|Bacteroidetes,1J194@117747|Sphingobacteriia	976|Bacteroidetes	MU	C-terminal domain of CHU protein family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_4,CHU_C,Calx-beta,He_PIG,NHL,TIG,fn3
TLS3_k127_3657035_5	1237149.C900_00007	1.072e-28	123.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	oprH	-	-	ko:K02014,ko:K07275,ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.2	-	-	OMP_b-brl,Plug,STN,TonB_dep_Rec
TLS3_k127_3666931_0	1336803.PHEL49_0095	7.319e-120	396.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,1HXGQ@117743|Flavobacteriia,3VW0G@52959|Polaribacter	976|Bacteroidetes	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
TLS3_k127_3666931_2	760192.Halhy_1974	1.129e-61	216.0	COG0315@1|root,COG0315@2|Bacteria,4NHA0@976|Bacteroidetes,1ISV2@117747|Sphingobacteriia	976|Bacteroidetes	H	Molybdenum cofactor biosynthesis protein	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
TLS3_k127_3666931_1	929703.KE386491_gene3652	2.899e-76	263.0	COG0664@1|root,COG0664@2|Bacteria,4PM2A@976|Bacteroidetes,47KHT@768503|Cytophagia	976|Bacteroidetes	T	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
TLS3_k127_3666931_4	643867.Ftrac_2998	9.236e-50	197.0	COG2885@1|root,COG2885@2|Bacteria,4NU83@976|Bacteroidetes,47VBR@768503|Cytophagia	976|Bacteroidetes	M	Pfam:DUF3308	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PorP_SprF
TLS3_k127_3666931_5	1121373.KB903627_gene2935	7.995e-23	115.0	COG3405@1|root,COG4886@1|root,COG3405@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,CHU_C,CW_binding_2,Flg_new,LRR_4,LRR_5
TLS3_k127_3666931_7	1086011.HJ01_03146	5.495e-09	70.0	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NSSE@237|Flavobacterium	976|Bacteroidetes	O	gliding motility-associated C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SBBP,SprB
TLS3_k127_3666931_6	471870.BACINT_04398	2.324e-12	76.0	COG1629@1|root,COG4219@1|root,COG4219@2|Bacteria,COG4771@2|Bacteria,4NDWS@976|Bacteroidetes,2FNCU@200643|Bacteroidia,4ANSE@815|Bacteroidaceae	976|Bacteroidetes	KT	COG NOG25147 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
TLS3_k127_3666931_3	984262.SGRA_1732	1.567e-51	188.0	COG1595@1|root,COG1595@2|Bacteria,4NR8J@976|Bacteroidetes	976|Bacteroidetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS3_k127_3676045_0	700598.Niako_3660	6.455e-214	667.0	COG3347@1|root,COG4221@1|root,COG3347@2|Bacteria,COG4221@2|Bacteria,4NEM0@976|Bacteroidetes,1IQ2J@117747|Sphingobacteriia	976|Bacteroidetes	IQ	rhamnulose-1-phosphate aldolase alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
TLS3_k127_3676045_1	1123248.KB893359_gene2079	2.266e-180	571.0	COG0697@1|root,2Z7ID@2|Bacteria,4NEHB@976|Bacteroidetes	976|Bacteroidetes	EG	L-rhamnose-proton symport protein (RhaT)	rhaT	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
TLS3_k127_3676045_2	742725.HMPREF9450_01247	1.486e-45	166.0	COG3254@1|root,COG3254@2|Bacteria,4NSEM@976|Bacteroidetes,2FT1N@200643|Bacteroidia	976|Bacteroidetes	G	Involved in the anomeric conversion of L-rhamnose	rhaU	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
TLS3_k127_3681404_0	1237149.C900_05118	1.798e-230	722.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,47MGS@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
TLS3_k127_3681404_1	1237149.C900_05119	2.346e-199	627.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,47JXW@768503|Cytophagia	976|Bacteroidetes	K	sigma54 specific, transcriptional regulator, Fis family	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
TLS3_k127_3681404_2	1237149.C900_05120	1.466e-35	141.0	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,47P8C@768503|Cytophagia	976|Bacteroidetes	S	Lipopolysaccharide-assembly	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
TLS3_k127_368152_2	1168034.FH5T_07295	6.234e-20	90.0	COG0226@1|root,COG0226@2|Bacteria,4PKGM@976|Bacteroidetes,2G3GH@200643|Bacteroidia	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_368152_0	1408473.JHXO01000001_gene2240	4.753e-217	680.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,2FPTN@200643|Bacteroidia	976|Bacteroidetes	M	gliding motility-associated lipoprotein GldK	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TLS3_k127_368152_1	1168034.FH5T_07285	2.64e-83	286.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,2FTZD@200643|Bacteroidia	976|Bacteroidetes	S	Gliding motility-associated protein, GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3692640_0	1454007.JAUG01000023_gene1316	0.0	1315.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1IP89@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
TLS3_k127_3692640_1	1237149.C900_05314	1.009e-159	519.0	COG4206@1|root,COG4206@2|Bacteria,4NGBJ@976|Bacteroidetes,47J8T@768503|Cytophagia	976|Bacteroidetes	H	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_3713179_3	1235803.C825_03528	2.493e-07	54.0	COG1943@1|root,COG1943@2|Bacteria,4NPPG@976|Bacteroidetes,2FTKF@200643|Bacteroidia,23217@171551|Porphyromonadaceae	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
TLS3_k127_3713179_2	388413.ALPR1_15854	2.434e-64	228.0	COG1595@1|root,COG1595@2|Bacteria,4NSN4@976|Bacteroidetes,47RXQ@768503|Cytophagia	976|Bacteroidetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
TLS3_k127_3713179_0	388413.ALPR1_15849	2.062e-209	680.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,47PE8@768503|Cytophagia	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NERD,Pkinase,TPR_12,TPR_8
TLS3_k127_3713179_1	388413.ALPR1_15844	5.372e-110	366.0	28HH2@1|root,2Z7ST@2|Bacteria,4NMWR@976|Bacteroidetes,47VP3@768503|Cytophagia	976|Bacteroidetes	M	Thiol-activated cytolysin	-	-	-	ko:K11031	ko02024,map02024	-	-	-	ko00000,ko00001,ko02042	-	-	-	Thiol_cytolysin
TLS3_k127_3714811_2	1237149.C900_05134	2.555e-44	163.0	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,47KJI@768503|Cytophagia	976|Bacteroidetes	L	PFAM Uncharacterised ACR, COG1259	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
TLS3_k127_3714811_0	1237149.C900_05133	3.857e-200	631.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,47KKZ@768503|Cytophagia	976|Bacteroidetes	F	PFAM Na dependent nucleoside transporter	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
TLS3_k127_3714811_1	761193.Runsl_2021	8.025e-132	428.0	COG5434@1|root,COG5434@2|Bacteria,4NE9Y@976|Bacteroidetes,47KM6@768503|Cytophagia	976|Bacteroidetes	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TLS3_k127_3722966_0	1123248.KB893328_gene890	3.074e-231	737.0	COG2133@1|root,COG2133@2|Bacteria,4NIJA@976|Bacteroidetes	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,GSDH,I-set,Ig_3
TLS3_k127_3722966_1	388413.ALPR1_14294	6.179e-66	248.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NI29@976|Bacteroidetes,47KZN@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,TPR_10,TPR_12,TPR_7,TPR_8
TLS3_k127_3722966_2	445961.IW15_08250	1.775e-28	118.0	COG1765@1|root,COG1765@2|Bacteria,4NFWN@976|Bacteroidetes,1HWTQ@117743|Flavobacteriia,3ZS0R@59732|Chryseobacterium	976|Bacteroidetes	O	Osmotically inducible protein OsmC	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
TLS3_k127_3729088_1	1086011.HJ01_02680	7.111e-131	420.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes,1HZ7N@117743|Flavobacteriia,2NTZG@237|Flavobacterium	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
TLS3_k127_3729088_3	1506583.JQJY01000001_gene352	2.656e-20	101.0	COG0589@1|root,COG0589@2|Bacteria,4NQ14@976|Bacteroidetes,1IDJ4@117743|Flavobacteriia,2NYJH@237|Flavobacterium	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_3729088_2	1461577.CCMH01000016_gene343	2.439e-37	151.0	COG0589@1|root,COG0589@2|Bacteria,4NHXF@976|Bacteroidetes,1HY7W@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_3729088_0	1089547.KB913013_gene310	2.792e-289	914.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,47JYI@768503|Cytophagia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
TLS3_k127_372969_1	1123248.KB893317_gene4384	5.224e-14	76.0	COG4251@1|root,COG4251@2|Bacteria,4PI98@976|Bacteroidetes,1IXDW@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_372969_0	504472.Slin_1754	6.4e-323	1027.0	COG0642@1|root,COG0784@1|root,COG3292@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47Y2E@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator three Y domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Reg_prop,Response_reg,Y_Y_Y
TLS3_k127_3741390_2	242619.PG_2042	0.0001422	45.0	COG0526@1|root,COG0526@2|Bacteria,4NGCC@976|Bacteroidetes,2FNK1@200643|Bacteroidia	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Redoxin,Thioredoxin_8
TLS3_k127_3741390_0	880526.KE386488_gene820	4.237e-85	302.0	COG4249@1|root,COG4249@2|Bacteria,4NNVR@976|Bacteroidetes,2FQ82@200643|Bacteroidia	976|Bacteroidetes	M	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TPR_16
TLS3_k127_3741390_1	1268240.ATFI01000001_gene2650	1.368e-18	95.0	2E9XM@1|root,3343C@2|Bacteria,4NVCJ@976|Bacteroidetes,2FQA6@200643|Bacteroidia,4AMCF@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
TLS3_k127_3741802_1	1237149.C900_01985	9.767e-60	216.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
TLS3_k127_3741802_0	1237149.C900_01986	1.107e-141	477.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NHKC@976|Bacteroidetes,47K54@768503|Cytophagia	976|Bacteroidetes	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,Wzz
TLS3_k127_376115_1	929703.KE386491_gene1336	7.88e-33	128.0	COG2207@1|root,COG2207@2|Bacteria,4NHSP@976|Bacteroidetes,47QVJ@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_376115_0	1250232.JQNJ01000001_gene3395	5.339e-74	253.0	COG2128@1|root,COG2128@2|Bacteria,4NI74@976|Bacteroidetes,1I27V@117743|Flavobacteriia	976|Bacteroidetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
TLS3_k127_376115_2	1239962.C943_00962	3.858e-21	106.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47UJH@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
TLS3_k127_3763258_0	1237149.C900_03712	3.417e-70	252.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NTSQ@976|Bacteroidetes	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,TPR_8
TLS3_k127_3763258_1	1122931.AUAE01000018_gene3923	7.134e-65	231.0	COG1082@1|root,COG2133@1|root,COG1082@2|Bacteria,COG2133@2|Bacteria,4NFKF@976|Bacteroidetes,2FRR2@200643|Bacteroidia,22XIX@171551|Porphyromonadaceae	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_3766161_1	929703.KE386491_gene1630	1.14e-218	691.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47KZX@768503|Cytophagia	976|Bacteroidetes	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
TLS3_k127_3766161_4	714943.Mucpa_6611	7.636e-72	259.0	COG3577@1|root,COG3577@2|Bacteria,4NNJX@976|Bacteroidetes,1ISCF@117747|Sphingobacteriia	976|Bacteroidetes	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
TLS3_k127_3766161_2	1120968.AUBX01000010_gene793	2.501e-178	566.0	COG0523@1|root,COG0523@2|Bacteria,4NENH@976|Bacteroidetes,47UFS@768503|Cytophagia	976|Bacteroidetes	S	Cobalamin synthesis protein cobW C-terminal domain	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
TLS3_k127_3766161_3	1443665.JACA01000003_gene604	9.934e-101	332.0	COG1131@1|root,COG1131@2|Bacteria,4NE3Z@976|Bacteroidetes,1HYPK@117743|Flavobacteriia,2YHY2@290174|Aquimarina	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_3766161_0	1237149.C900_05089	0.0	1326.0	COG4773@1|root,COG4773@2|Bacteria,4NF92@976|Bacteroidetes,47M11@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
TLS3_k127_3788880_1	1237149.C900_05254	1.627e-147	477.0	COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,47MB7@768503|Cytophagia	976|Bacteroidetes	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_3788880_3	1237149.C900_05253	2.136e-100	331.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,47JSN@768503|Cytophagia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_3788880_5	1237149.C900_05252	9.403e-80	271.0	COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,47P77@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
TLS3_k127_3788880_4	1237149.C900_02624	5.66e-92	307.0	2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,47P85@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
TLS3_k127_3788880_2	485917.Phep_2946	3.042e-118	384.0	COG0247@1|root,COG0247@2|Bacteria,4NIMP@976|Bacteroidetes,1INN8@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
TLS3_k127_3788880_0	391596.PBAL39_19404	3.236e-229	717.0	COG1139@1|root,COG1139@2|Bacteria,4NEBT@976|Bacteroidetes,1IR6B@117747|Sphingobacteriia	976|Bacteroidetes	C	4Fe-4S ferredoxin	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
TLS3_k127_3788880_6	926549.KI421517_gene3225	9.36e-64	224.0	COG1556@1|root,COG1556@2|Bacteria,4NQSF@976|Bacteroidetes,47QGX@768503|Cytophagia	976|Bacteroidetes	S	LUD domain	lutC	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
TLS3_k127_380773_4	1122621.ATZA01000037_gene3504	1.572e-78	268.0	COG0077@1|root,COG0077@2|Bacteria,4NEEK@976|Bacteroidetes,1IQJU@117747|Sphingobacteriia	976|Bacteroidetes	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
TLS3_k127_380773_2	1249997.JHZW01000003_gene3837	3.343e-144	467.0	COG0436@1|root,COG0436@2|Bacteria,4NF2E@976|Bacteroidetes,1HXQX@117743|Flavobacteriia,2PH11@252356|Maribacter	976|Bacteroidetes	E	Aminotransferase class I and II	dapL	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_380773_3	1279009.ADICEAN_04036	1.598e-96	323.0	COG0287@1|root,COG0287@2|Bacteria,4NEKF@976|Bacteroidetes,47N0Z@768503|Cytophagia	976|Bacteroidetes	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
TLS3_k127_380773_1	1279009.ADICEAN_04037	1.11e-171	545.0	COG2876@1|root,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,47K32@768503|Cytophagia	976|Bacteroidetes	E	chorismate mutase	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
TLS3_k127_380773_0	643867.Ftrac_0151	2.653e-178	597.0	COG0457@1|root,COG2849@1|root,COG0457@2|Bacteria,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47N8G@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TPR_1,TPR_16,TPR_8
TLS3_k127_380773_5	1227739.Hsw_3533	1.453e-09	63.0	COG1305@1|root,COG1305@2|Bacteria,4NI6P@976|Bacteroidetes,47KR7@768503|Cytophagia	976|Bacteroidetes	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
TLS3_k127_3819131_3	1122179.KB890414_gene1773	6.375e-06	54.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1IPGD@117747|Sphingobacteriia	976|Bacteroidetes	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
TLS3_k127_3819131_0	1237149.C900_02108	2.315e-85	289.0	COG3298@1|root,COG3298@2|Bacteria,4NECH@976|Bacteroidetes,47Y3D@768503|Cytophagia	976|Bacteroidetes	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
TLS3_k127_3819131_1	1237149.C900_02109	2.449e-53	190.0	2AGNU@1|root,316WB@2|Bacteria,4NSNZ@976|Bacteroidetes,47RK1@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3819131_2	1120965.AUBV01000001_gene3457	3.921e-34	132.0	COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,47P2Z@768503|Cytophagia	976|Bacteroidetes	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GTA_TIM
TLS3_k127_3860491_2	1189620.AJXL01000013_gene2464	3.916e-56	207.0	COG0457@1|root,COG0457@2|Bacteria,4NGMH@976|Bacteroidetes,1HZM6@117743|Flavobacteriia,2NUR1@237|Flavobacterium	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,TPR_19
TLS3_k127_3860491_0	1121481.AUAS01000012_gene342	0.0	1517.0	COG1409@1|root,COG4775@1|root,COG1409@2|Bacteria,COG4775@2|Bacteria,4NF9N@976|Bacteroidetes,47JAP@768503|Cytophagia	976|Bacteroidetes	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Metallophos,ShlB
TLS3_k127_3868654_4	1173023.KE650771_gene5116	8.609e-20	94.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_3868654_2	1121897.AUGO01000015_gene3384	4.079e-48	174.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1I33I@117743|Flavobacteriia,2NWE0@237|Flavobacterium	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
TLS3_k127_3868654_1	1237149.C900_05818	5.996e-147	469.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,47NRU@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
TLS3_k127_3868654_3	929703.KE386491_gene2893	5.881e-21	96.0	2C5P8@1|root,32U6D@2|Bacteria,4NSY7@976|Bacteroidetes,47R86@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3868654_0	1237149.C900_05825	1.183e-159	512.0	COG3000@1|root,COG3000@2|Bacteria,4NFWX@976|Bacteroidetes,47KXY@768503|Cytophagia	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
TLS3_k127_389175_1	929562.Emtol_3626	1.368e-215	677.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,COG4654@2|Bacteria,4NDVK@976|Bacteroidetes,47P0X@768503|Cytophagia	976|Bacteroidetes	CG	Carbohydrate binding module (family 6)	-	-	-	ko:K08738,ko:K09992	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	CBM_6,Cytochrom_C,GSDH,PKD,ThuA
TLS3_k127_389175_0	1237149.C900_05842	4.233e-291	924.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,47NIF@768503|Cytophagia	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_8
TLS3_k127_3892630_2	1237149.C900_04501	5.183e-98	324.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,4NFBV@976|Bacteroidetes,47K85@768503|Cytophagia	976|Bacteroidetes	EQ	Hydantoinase/oxoprolinase	-	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
TLS3_k127_3892630_1	1237149.C900_00911	3.535e-164	521.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,47JMK@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
TLS3_k127_3892630_0	926549.KI421517_gene2095	2.132e-166	554.0	COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,47KV2@768503|Cytophagia	976|Bacteroidetes	M	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
TLS3_k127_3892630_5	1237149.C900_00906	3.078e-50	190.0	COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,47Q8I@768503|Cytophagia	976|Bacteroidetes	T	PFAM Prokaryotic dksA traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
TLS3_k127_3892630_4	1237149.C900_00905	3.299e-84	283.0	COG1386@1|root,COG1386@2|Bacteria,4NPG3@976|Bacteroidetes,47NG4@768503|Cytophagia	976|Bacteroidetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
TLS3_k127_3892630_3	1229276.DI53_0453	6.534e-93	323.0	COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,1INNI@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS3_k127_3904727_0	1237149.C900_04377	1.995e-212	668.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,47MP5@768503|Cytophagia	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
TLS3_k127_3904727_1	153721.MYP_510	2.063e-164	530.0	COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,47KPD@768503|Cytophagia	976|Bacteroidetes	J	tRNA synthetase class II core domain (G, H, P, S and T)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
TLS3_k127_3906425_2	471854.Dfer_2445	3.333e-75	254.0	COG0251@1|root,COG0251@2|Bacteria,4NNXK@976|Bacteroidetes,47Q05@768503|Cytophagia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
TLS3_k127_3906425_0	471854.Dfer_2442	6.589e-269	838.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,47JGM@768503|Cytophagia	976|Bacteroidetes	G	COGs COG2133 Glucose sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
TLS3_k127_3906425_1	504472.Slin_3968	5.59e-155	493.0	COG1921@1|root,COG1921@2|Bacteria,4PN21@976|Bacteroidetes,47Y5Q@768503|Cytophagia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,Cys_Met_Meta_PP
TLS3_k127_3929876_4	296591.Bpro_3613	3.737e-21	94.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,4ACIR@80864|Comamonadaceae	28216|Betaproteobacteria	NU	pilus assembly protein FimV	fimV	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
TLS3_k127_3929876_5	1121904.ARBP01000003_gene6150	1.841e-13	72.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,47KEQ@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM Aspartate kinase	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
TLS3_k127_3929876_2	1279009.ADICEAN_03480	7.527e-79	267.0	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,47P9H@768503|Cytophagia	976|Bacteroidetes	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
TLS3_k127_3929876_7	929562.Emtol_2942	0.0009318	47.0	COG3266@1|root,COG3266@2|Bacteria,4NNQN@976|Bacteroidetes,47PZT@768503|Cytophagia	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3929876_0	945713.IALB_0592	0.0	1044.0	COG3808@1|root,COG3808@2|Bacteria	2|Bacteria	C	hydrogen-translocating pyrophosphatase activity	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
TLS3_k127_3929876_3	1237149.C900_01197	2.903e-49	179.0	COG4731@1|root,COG4731@2|Bacteria,4NQCK@976|Bacteroidetes	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
TLS3_k127_3929876_1	1237149.C900_01196	5.518e-90	299.0	COG1595@1|root,COG1595@2|Bacteria,4NX8R@976|Bacteroidetes,47PIG@768503|Cytophagia	976|Bacteroidetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF,Sigma70_r2
TLS3_k127_393042_2	1185876.BN8_05130	3.82e-13	72.0	COG1082@1|root,COG1082@2|Bacteria,4NFMD@976|Bacteroidetes,47NNJ@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_393042_0	1123278.KB893554_gene3983	5.387e-170	542.0	COG0119@1|root,COG0119@2|Bacteria,4NEIT@976|Bacteroidetes,47N2Y@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
TLS3_k127_393042_1	929713.NIASO_00655	8.665e-164	519.0	COG0473@1|root,COG0473@2|Bacteria,4NEBE@976|Bacteroidetes,1INYR@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
TLS3_k127_3931422_3	269798.CHU_3575	2.808e-44	163.0	COG2346@1|root,COG2346@2|Bacteria,4NTJR@976|Bacteroidetes,47RRK@768503|Cytophagia	976|Bacteroidetes	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
TLS3_k127_3931422_1	1250232.JQNJ01000001_gene1351	1.409e-147	477.0	COG3503@1|root,COG3503@2|Bacteria,4NFAF@976|Bacteroidetes,1HX24@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
TLS3_k127_3931422_5	304371.MCP_2981	5.846e-22	100.0	COG0456@1|root,arCOG00833@2157|Archaea,2XXV1@28890|Euryarchaeota	28890|Euryarchaeota	S	COG1246 N-acetylglutamate synthase and related acetyltransferases	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
TLS3_k127_3931422_2	761193.Runsl_4128	2.261e-115	377.0	COG0500@1|root,COG1246@1|root,COG1246@2|Bacteria,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,47MVN@768503|Cytophagia	976|Bacteroidetes	Q	Hypothetical methyltransferase	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
TLS3_k127_3931422_4	1123248.KB893315_gene3111	2.22e-41	154.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,1IYKS@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
TLS3_k127_3931422_0	925409.KI911562_gene2337	7.556e-316	979.0	COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,1IR7E@117747|Sphingobacteriia	976|Bacteroidetes	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
TLS3_k127_393787_0	1124780.ANNU01000020_gene3319	2.027e-74	264.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,47KES@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
TLS3_k127_393787_2	236814.IX39_05150	5.393e-29	122.0	2E4AP@1|root,32Z6C@2|Bacteria,4NWDP@976|Bacteroidetes,1I55P@117743|Flavobacteriia,3ZRMH@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_393787_1	926549.KI421517_gene1257	2.822e-36	158.0	COG2374@1|root,COG4932@1|root,COG2374@2|Bacteria,COG4932@2|Bacteria,4NHFV@976|Bacteroidetes,47M74@768503|Cytophagia	976|Bacteroidetes	M	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHB_HEX_C_1,Exo_endo_phos
TLS3_k127_3945424_1	504472.Slin_1809	1.502e-49	184.0	COG1983@1|root,COG1983@2|Bacteria,4NS0M@976|Bacteroidetes,47QMV@768503|Cytophagia	976|Bacteroidetes	KT	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
TLS3_k127_3945424_0	929556.Solca_2890	4.023e-190	604.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1IQJT@117747|Sphingobacteriia	976|Bacteroidetes	V	Mate efflux family protein	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
TLS3_k127_395389_1	443143.GM18_3522	6.99e-55	196.0	COG0745@1|root,COG0745@2|Bacteria,1RD6H@1224|Proteobacteria,42S64@68525|delta/epsilon subdivisions,2WPJC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_395389_0	1173027.Mic7113_2453	2.987e-106	383.0	COG2202@1|root,COG2203@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,1G2QC@1117|Cyanobacteria,1HH4R@1150|Oscillatoriales	1117|Cyanobacteria	T	Domain of unknown function (DUF4118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
TLS3_k127_398006_3	1279009.ADICEAN_01897	1.518e-17	83.0	COG5512@1|root,COG5512@2|Bacteria,4NXIK@976|Bacteroidetes,47S8C@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
TLS3_k127_398006_1	1124780.ANNU01000006_gene2886	2.911e-116	384.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,47JMB@768503|Cytophagia	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
TLS3_k127_398006_0	1237149.C900_04665	2.471e-170	541.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,47M0Z@768503|Cytophagia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
TLS3_k127_398006_2	1237149.C900_04663	1.537e-87	295.0	COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,47PPQ@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
TLS3_k127_398416_1	468059.AUHA01000003_gene1738	9.808e-140	455.0	COG0025@1|root,COG0025@2|Bacteria	2|Bacteria	P	sodium:proton antiporter activity	sod22	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
TLS3_k127_398416_0	714943.Mucpa_7156	3.942e-203	644.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
TLS3_k127_398416_2	1270193.JARP01000001_gene2240	1.412e-26	113.0	2A3Y3@1|root,30SGF@2|Bacteria,4NZA3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_398663_0	1535422.ND16A_0651	6.374e-91	327.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K03407,ko:K07678	ko02020,ko02025,ko02026,ko02030,ko05111,map02020,map02025,map02026,map02030,map05111	M00475,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg
TLS3_k127_398663_1	1237149.C900_01354	7.02e-71	267.0	COG2203@1|root,COG2203@2|Bacteria,4NICW@976|Bacteroidetes,47NI3@768503|Cytophagia	976|Bacteroidetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,PAS_9
TLS3_k127_398663_3	1089547.KB913013_gene1600	4.247e-26	108.0	COG3530@1|root,COG3530@2|Bacteria,4NUSP@976|Bacteroidetes,47RWJ@768503|Cytophagia	976|Bacteroidetes	S	Putative quorum-sensing-regulated virulence factor	-	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
TLS3_k127_398663_2	1047013.AQSP01000134_gene1348	2.568e-68	243.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_398886_10	1121481.AUAS01000003_gene3935	2.212e-17	81.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,47KPI@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
TLS3_k127_398886_1	880070.Cycma_2058	2.905e-178	567.0	COG0738@1|root,COG0738@2|Bacteria,4NEB2@976|Bacteroidetes,47KY1@768503|Cytophagia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_398886_3	509635.N824_27980	1.056e-119	396.0	COG3385@1|root,COG3385@2|Bacteria,4NIN4@976|Bacteroidetes,1IPK8@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
TLS3_k127_398886_5	203122.Sde_2917	2.772e-85	290.0	COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,1S21M@1236|Gammaproteobacteria,467A8@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_398886_4	1237149.C900_04081	4.638e-115	376.0	COG1045@1|root,COG1045@2|Bacteria,4NGZ7@976|Bacteroidetes,47JAY@768503|Cytophagia	976|Bacteroidetes	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
TLS3_k127_398886_2	1305737.JAFX01000001_gene3414	1.81e-149	477.0	COG0031@1|root,COG0031@2|Bacteria,4NF7E@976|Bacteroidetes,47J9D@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_398886_8	324057.Pjdr2_2693	2.424e-38	148.0	COG0454@1|root,COG0456@2|Bacteria,1VBAE@1239|Firmicutes	1239|Firmicutes	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
TLS3_k127_398886_7	880070.Cycma_4909	1.707e-55	203.0	COG2755@1|root,COG2755@2|Bacteria,4NMGQ@976|Bacteroidetes,47QU7@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS3_k127_398886_12	1144313.PMI10_01764	6.397e-10	68.0	COG3652@1|root,COG3652@2|Bacteria,4NQE9@976|Bacteroidetes,1I261@117743|Flavobacteriia,2NUP8@237|Flavobacterium	976|Bacteroidetes	S	membrane	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
TLS3_k127_398886_6	1237149.C900_00447	1.233e-55	199.0	COG0783@1|root,COG0783@2|Bacteria,4NQD2@976|Bacteroidetes,47XQU@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
TLS3_k127_398886_11	1237149.C900_05239	1.312e-12	75.0	COG1393@1|root,COG1393@2|Bacteria	2|Bacteria	P	arsenate reductase (glutaredoxin) activity	arsC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
TLS3_k127_398886_0	1279009.ADICEAN_03468	1.075e-193	615.0	COG3263@1|root,COG3263@2|Bacteria,4NFNS@976|Bacteroidetes,47P2K@768503|Cytophagia	976|Bacteroidetes	P	TrkA-C domain	cvrA	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
TLS3_k127_398886_13	1123279.ATUS01000001_gene1457	4.586e-08	59.0	COG0346@1|root,COG0346@2|Bacteria,1RIR2@1224|Proteobacteria,1S7P4@1236|Gammaproteobacteria,1J6FS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_398886_9	1121904.ARBP01000027_gene713	3.075e-33	132.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes	976|Bacteroidetes	V	permease	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_399255_6	1123248.KB893315_gene2987	3.787e-27	112.0	COG4430@1|root,COG4430@2|Bacteria,4NR0U@976|Bacteroidetes,1IT28@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
TLS3_k127_399255_4	1121859.KB890756_gene1478	3.898e-40	154.0	COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,47QE6@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
TLS3_k127_399255_0	1237149.C900_02591	1.803e-131	451.0	COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_399255_5	388413.ALPR1_13979	8.36e-33	130.0	COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QZJ@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_399255_2	1121957.ATVL01000008_gene4578	9.432e-104	344.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,47N6P@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the pirin family	yhhW	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
TLS3_k127_399255_1	929556.Solca_0019	4.402e-120	391.0	COG1741@1|root,COG1741@2|Bacteria,4NN4X@976|Bacteroidetes,1J089@117747|Sphingobacteriia	976|Bacteroidetes	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
TLS3_k127_399255_3	330214.NIDE0047	1.073e-48	179.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	tdsD	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
TLS3_k127_400998_2	388413.ALPR1_04723	1.619e-51	186.0	COG2869@1|root,COG2869@2|Bacteria,4NF7A@976|Bacteroidetes,47KUU@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
TLS3_k127_400998_0	1313301.AUGC01000008_gene499	1.296e-93	312.0	COG1347@1|root,COG1347@2|Bacteria,4NGD9@976|Bacteroidetes	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrD	-	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
TLS3_k127_400998_1	1279009.ADICEAN_03177	2.141e-87	292.0	COG2209@1|root,COG2209@2|Bacteria,4NEU0@976|Bacteroidetes,47KRI@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
TLS3_k127_400998_3	1120965.AUBV01000008_gene1932	2.656e-26	112.0	COG2928@1|root,COG2928@2|Bacteria,4NR4F@976|Bacteroidetes,47QB1@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
TLS3_k127_4022684_1	1124780.ANNU01000038_gene172	9.396e-172	556.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia	976|Bacteroidetes	DM	TIGRFAM capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
TLS3_k127_4022684_2	1123057.P872_11480	1.783e-85	290.0	COG1596@1|root,COG1596@2|Bacteria,4NNJT@976|Bacteroidetes,47PCB@768503|Cytophagia	976|Bacteroidetes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
TLS3_k127_4022684_0	926549.KI421517_gene2617	2.011e-173	556.0	COG0438@1|root,COG0438@2|Bacteria,4NGU7@976|Bacteroidetes,47P3E@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	ko:K03208	-	-	-	-	ko00000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_4022684_3	1237149.C900_03507	1.906e-40	151.0	COG1544@1|root,COG1544@2|Bacteria,4NUME@976|Bacteroidetes,47RC7@768503|Cytophagia	976|Bacteroidetes	J	PFAM Sigma 54 modulation protein S30EA ribosomal protein	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
TLS3_k127_403013_1	760192.Halhy_3320	1.182e-222	696.0	COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,1IP02@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the xylose isomerase family	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	-
TLS3_k127_403013_2	1121904.ARBP01000006_gene3710	4.481e-201	639.0	COG1070@1|root,COG1070@2|Bacteria,4NFBZ@976|Bacteroidetes,47KIK@768503|Cytophagia	976|Bacteroidetes	G	PFAM FGGY family of carbohydrate kinases, N-terminal domain	xylB_2	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
TLS3_k127_403013_3	377629.TERTU_4670	3.428e-97	322.0	COG1051@1|root,COG1051@2|Bacteria,1QTT4@1224|Proteobacteria,1RQ35@1236|Gammaproteobacteria,2PMWV@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	F	NUDIX domain	nuhA	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_403013_5	269798.CHU_1032	9.191e-69	240.0	COG2755@1|root,COG2755@2|Bacteria,4NNIC@976|Bacteroidetes,47PEW@768503|Cytophagia	976|Bacteroidetes	E	PFAM GDSL-like Lipase Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS3_k127_403013_0	468059.AUHA01000004_gene2204	0.0	1062.0	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1IRII@117747|Sphingobacteriia	976|Bacteroidetes	G	phosphorylase	-	-	2.4.1.8	ko:K00691	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
TLS3_k127_403013_4	1321778.HMPREF1982_00965	8.24e-74	254.0	COG0637@1|root,COG0637@2|Bacteria,1UZE0@1239|Firmicutes,24DWR@186801|Clostridia	186801|Clostridia	S	Haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
TLS3_k127_403013_6	313596.RB2501_14094	4.3e-58	206.0	COG0524@1|root,COG0524@2|Bacteria,4NJIK@976|Bacteroidetes,1I00V@117743|Flavobacteriia	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
TLS3_k127_403322_4	376686.Fjoh_0904	9.262e-50	182.0	COG1943@1|root,COG1943@2|Bacteria,4NRU8@976|Bacteroidetes,1I4RI@117743|Flavobacteriia,2NWHW@237|Flavobacterium	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
TLS3_k127_403322_0	1048983.EL17_20455	1.806e-185	595.0	COG0249@1|root,COG0249@2|Bacteria,4NGEA@976|Bacteroidetes,47NI1@768503|Cytophagia	976|Bacteroidetes	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V
TLS3_k127_403322_3	1185876.BN8_00177	3.935e-77	265.0	COG3342@1|root,COG3342@2|Bacteria,4NITT@976|Bacteroidetes,47JYE@768503|Cytophagia	976|Bacteroidetes	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,TPR_16,TPR_19
TLS3_k127_403322_2	743722.Sph21_3744	4.991e-82	278.0	COG2197@1|root,COG2197@2|Bacteria,4NMX5@976|Bacteroidetes,1IXU1@117747|Sphingobacteriia	976|Bacteroidetes	K	SMART Signal transduction response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_403322_1	743722.Sph21_3745	1.381e-85	293.0	COG4585@1|root,COG4585@2|Bacteria,4NG0M@976|Bacteroidetes,1IV2W@117747|Sphingobacteriia	976|Bacteroidetes	T	Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor	narQ	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,PilJ
TLS3_k127_4055678_4	1242864.D187_004781	2.697e-45	178.0	COG2730@1|root,COG2730@2|Bacteria,1R544@1224|Proteobacteria	1224|Proteobacteria	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
TLS3_k127_4055678_5	1121957.ATVL01000006_gene2493	3.602e-05	55.0	COG1874@1|root,COG2755@1|root,COG1874@2|Bacteria,COG2755@2|Bacteria,4PPB9@976|Bacteroidetes,47VD8@768503|Cytophagia	976|Bacteroidetes	E	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	PA14
TLS3_k127_4055678_2	1121904.ARBP01000004_gene1111	2.311e-211	672.0	COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,47JQH@768503|Cytophagia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	amyA2	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,tRNA_SAD
TLS3_k127_4055678_3	1124780.ANNU01000023_gene3232	4.182e-195	621.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,47MR6@768503|Cytophagia	976|Bacteroidetes	G	PFAM Alpha amylase, catalytic	-	GO:0000272,GO:0000287,GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0016020,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0019867,GO:0030246,GO:0030247,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046872,GO:0071704,GO:1901575,GO:2001070	3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54	ko:K01176,ko:K01208	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,BACON,DUF3459
TLS3_k127_4055678_1	1123234.AUKI01000023_gene1952	2.812e-229	726.0	COG0366@1|root,COG0366@2|Bacteria,4NFMM@976|Bacteroidetes,1HZ0S@117743|Flavobacteriia	976|Bacteroidetes	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
TLS3_k127_4055678_0	1237149.C900_02046	0.0	1056.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,4NFE4@976|Bacteroidetes,47Y5G@768503|Cytophagia	976|Bacteroidetes	G	Maltogenic Amylase, C-terminal domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
TLS3_k127_4059331_3	1538644.KO02_09560	2.181e-75	257.0	COG3391@1|root,COG3391@2|Bacteria,4NH92@976|Bacteroidetes,1IQ1F@117747|Sphingobacteriia	976|Bacteroidetes	S	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128
TLS3_k127_4059331_0	761193.Runsl_1740	2.577e-214	672.0	COG3458@1|root,COG3458@2|Bacteria,4NGH5@976|Bacteroidetes,47MHG@768503|Cytophagia	976|Bacteroidetes	Q	PFAM Acetyl xylan esterase	axe7A_2	-	-	-	-	-	-	-	-	-	-	-	AXE1
TLS3_k127_4059331_2	468059.AUHA01000002_gene847	3.469e-92	307.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,1IXDR@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptide methionine sulfoxide reductase	msrA1	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
TLS3_k127_4059331_1	714943.Mucpa_4492	1.033e-139	451.0	COG0604@1|root,COG0604@2|Bacteria,4NEYW@976|Bacteroidetes,1IP5X@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Alcohol dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
TLS3_k127_4060279_2	760192.Halhy_5136	1.837e-145	465.0	COG2133@1|root,COG3241@1|root,COG2133@2|Bacteria,COG3241@2|Bacteria,4NEMM@976|Bacteroidetes,1IUR8@117747|Sphingobacteriia	976|Bacteroidetes	CG	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
TLS3_k127_4060279_0	760192.Halhy_5137	5.81e-187	602.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NEJ0@976|Bacteroidetes,1IS7J@117747|Sphingobacteriia	976|Bacteroidetes	CG	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_4060279_3	760192.Halhy_2281	5.901e-102	340.0	COG1082@1|root,COG1082@2|Bacteria,4NGKX@976|Bacteroidetes,1IQY9@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_4060279_1	760192.Halhy_2280	5.372e-150	478.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4PIZU@976|Bacteroidetes,1IYUX@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TLS3_k127_4074772_1	926549.KI421517_gene2767	1.686e-169	543.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,47K3T@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
TLS3_k127_4074772_0	1237149.C900_03366	0.0	1241.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,47MI5@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
TLS3_k127_4074772_2	1237149.C900_03364	1.735e-75	265.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,47PY8@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit III	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
TLS3_k127_4074772_3	1237149.C900_03363	7.136e-30	123.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,47KT1@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase accessory protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
TLS3_k127_4084246_1	1237149.C900_05729	1.496e-80	276.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
TLS3_k127_4084246_0	1237149.C900_05728	3.633e-222	695.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia	976|Bacteroidetes	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_4084400_1	385682.AFSL01000040_gene257	1.344e-68	240.0	COG0583@1|root,COG0583@2|Bacteria,4NGZ5@976|Bacteroidetes,2FNH6@200643|Bacteroidia,3XJM8@558415|Marinilabiliaceae	976|Bacteroidetes	K	Bacterial regulatory helix-turn-helix protein, lysR family	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
TLS3_k127_4084400_0	929703.KE386491_gene1724	1.345e-89	311.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_4086054_2	1237149.C900_01904	5.663e-39	153.0	COG0642@1|root,COG2205@2|Bacteria,4NTSQ@976|Bacteroidetes	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
TLS3_k127_4086054_0	1237149.C900_01903	5.644e-141	465.0	COG0457@1|root,COG0457@2|Bacteria	1237149.C900_01903|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4086054_1	1237149.C900_01902	4.039e-90	306.0	COG0226@1|root,COG0226@2|Bacteria,4PKGM@976|Bacteroidetes	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_4086054_3	643867.Ftrac_0359	3.824e-23	100.0	COG3391@1|root,COG5644@1|root,COG3391@2|Bacteria,COG5644@2|Bacteria,4PMIF@976|Bacteroidetes	976|Bacteroidetes	E	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	HYR,Laminin_G_3
TLS3_k127_4110267_1	1047013.AQSP01000070_gene34	6.534e-104	364.0	COG3292@1|root,COG3920@1|root,COG3292@2|Bacteria,COG3920@2|Bacteria,2NNZT@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	pdtaS	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2,Reg_prop,Y_Y_Y
TLS3_k127_4110267_0	743722.Sph21_1203	8.287e-114	376.0	COG0457@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IT7X@117747|Sphingobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,TPR_2,TPR_8
TLS3_k127_4116873_3	1237149.C900_04595	2.149e-85	289.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,47K6R@768503|Cytophagia	976|Bacteroidetes	M	Penicillin binding protein transpeptidase	pbpB	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
TLS3_k127_4116873_2	1237149.C900_03457	1.124e-158	511.0	COG0624@1|root,COG0624@2|Bacteria,4NI66@976|Bacteroidetes,47NB9@768503|Cytophagia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
TLS3_k127_4116873_0	1237149.C900_04608	3.089e-236	756.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,47KTA@768503|Cytophagia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
TLS3_k127_4116873_5	1121904.ARBP01000004_gene849	2.082e-58	209.0	COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,47J8W@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM TIGR02453 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
TLS3_k127_4116873_1	1237149.C900_01734	3.709e-164	526.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,47MCP@768503|Cytophagia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_4116873_4	1237149.C900_01735	1.014e-72	254.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,47MFU@768503|Cytophagia	976|Bacteroidetes	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS3_k127_41826_1	1237149.C900_01416	2.368e-90	307.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,47NA5@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_41826_2	1237149.C900_01417	4.734e-75	263.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_41826_0	1237149.C900_01418	0.0	1037.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,47KKH@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
TLS3_k127_4185826_2	763034.HMPREF9446_03500	2.353e-09	68.0	COG1216@1|root,COG1216@2|Bacteria,4NSTS@976|Bacteroidetes,2FTVK@200643|Bacteroidia,4AVD9@815|Bacteroidaceae	976|Bacteroidetes	S	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_4185826_0	1121948.AUAC01000008_gene785	4.29e-66	232.0	COG0438@1|root,COG0438@2|Bacteria,1RJ7A@1224|Proteobacteria,2UB3V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4185826_3	1183377.Py04_0763	9.42e-06	57.0	COG0392@1|root,arCOG00899@2157|Archaea,2Y3DU@28890|Euryarchaeota,242YG@183968|Thermococci	183968|Thermococci	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
TLS3_k127_4185826_1	679926.Mpet_1408	3.928e-47	177.0	COG0500@1|root,arCOG01773@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
TLS3_k127_4206153_1	1123248.KB893326_gene1451	3.881e-35	137.0	COG2149@1|root,COG2149@2|Bacteria,4NSIV@976|Bacteroidetes,1IYG8@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
TLS3_k127_4206153_3	1168034.FH5T_20200	4.082e-19	88.0	COG0607@1|root,31225@2|Bacteria,4PGX1@976|Bacteroidetes,2FW1F@200643|Bacteroidia	976|Bacteroidetes	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
TLS3_k127_4206153_2	700598.Niako_0840	4.09e-25	108.0	2DZT3@1|root,32VI6@2|Bacteria,4NSPZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4206153_0	714943.Mucpa_1942	4.678e-127	410.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPSY@117747|Sphingobacteriia	976|Bacteroidetes	V	Protein export membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS3_k127_4207469_0	1189612.A33Q_2236	8.597e-117	406.0	COG1629@1|root,COG1629@2|Bacteria,4NMTD@976|Bacteroidetes,47PTS@768503|Cytophagia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
TLS3_k127_4207469_1	1239962.C943_02512	4.27e-20	89.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,47JQE@768503|Cytophagia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
TLS3_k127_4219394_4	761193.Runsl_2021	2.322e-14	74.0	COG5434@1|root,COG5434@2|Bacteria,4NE9Y@976|Bacteroidetes,47KM6@768503|Cytophagia	976|Bacteroidetes	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TLS3_k127_4219394_1	504472.Slin_3273	1.681e-126	413.0	COG5434@1|root,COG5434@2|Bacteria,4NFZJ@976|Bacteroidetes,47K9P@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,fn3
TLS3_k127_4219394_3	195250.CM001776_gene701	2.3e-64	228.0	COG0566@1|root,COG0566@2|Bacteria,1G05W@1117|Cyanobacteria,1GZCG@1129|Synechococcus	1117|Cyanobacteria	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylas_C,SpoU_methylase
TLS3_k127_4219394_2	1237149.C900_05832	1.345e-74	256.0	COG2949@1|root,COG2949@2|Bacteria,4NNQS@976|Bacteroidetes,47MWP@768503|Cytophagia	976|Bacteroidetes	S	DUF218 domain	-	-	-	ko:K03748	-	-	-	-	ko00000	-	-	-	DUF218
TLS3_k127_4219394_0	1237149.C900_05833	6.277e-231	726.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,47MA1@768503|Cytophagia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_4237_4	643867.Ftrac_1238	7.781e-19	86.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,47KE6@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_4237_0	1123278.KB893388_gene5775	2.066e-129	442.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47K1N@768503|Cytophagia	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
TLS3_k127_4237_5	1124780.ANNU01000002_gene1482	7.167e-17	85.0	COG0693@1|root,COG0693@2|Bacteria,4NGII@976|Bacteroidetes,47K2N@768503|Cytophagia	976|Bacteroidetes	C	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
TLS3_k127_4237_1	1237149.C900_04540	8.786e-78	273.0	COG0457@1|root,COG0457@2|Bacteria,4NEYK@976|Bacteroidetes,47TJF@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
TLS3_k127_4237_3	867900.Celly_0967	9.112e-60	215.0	COG0693@1|root,COG0693@2|Bacteria,4NEPR@976|Bacteroidetes,1HXC2@117743|Flavobacteriia	976|Bacteroidetes	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
TLS3_k127_4237_2	929703.KE386491_gene31	5.582e-66	234.0	COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,47PMI@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
TLS3_k127_4241176_5	1336803.PHEL49_1527	2.057e-14	73.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,1HX58@117743|Flavobacteriia,3VV4K@52959|Polaribacter	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
TLS3_k127_4241176_2	1237149.C900_01616	4.11e-143	470.0	COG1293@1|root,COG1293@2|Bacteria,4NGP5@976|Bacteroidetes,47M54@768503|Cytophagia	976|Bacteroidetes	K	Fibronectin-binding protein A N-terminus (FbpA)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
TLS3_k127_4241176_0	1237149.C900_01617	4.678e-204	646.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,47JS3@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
TLS3_k127_4241176_3	1124780.ANNU01000045_gene2312	3.364e-37	142.0	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,47R56@768503|Cytophagia	976|Bacteroidetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TLS3_k127_4241176_1	1305737.JAFX01000001_gene723	5.007e-173	547.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,47MQI@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_425575_3	171693.BN988_00343	1.629e-18	91.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,23IZG@182709|Oceanobacillus	91061|Bacilli	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,TPR_2,TPR_8
TLS3_k127_425575_0	1237149.C900_04399	1.104e-171	549.0	COG0501@1|root,COG0501@2|Bacteria,4NESF@976|Bacteroidetes,47KTS@768503|Cytophagia	976|Bacteroidetes	O	Zn-dependent protease with chaperone function	-	-	3.4.24.84	ko:K03799,ko:K06013	ko00900,ko01130,map00900,map01130	M00743	R09845	RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
TLS3_k127_425575_1	485918.Cpin_4084	4.673e-76	261.0	COG3279@1|root,COG3279@2|Bacteria,4NF8U@976|Bacteroidetes	976|Bacteroidetes	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_425575_2	700598.Niako_0643	9.273e-50	184.0	COG2972@1|root,COG2972@2|Bacteria,4NIRC@976|Bacteroidetes,1J05H@117747|Sphingobacteriia	976|Bacteroidetes	T	Signal transduction histidine kinase, LytS	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
TLS3_k127_4261594_0	1237149.C900_04022	2.356e-167	534.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,47MHR@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
TLS3_k127_4261594_3	1237149.C900_04023	1.78e-38	146.0	2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,47RC2@768503|Cytophagia	976|Bacteroidetes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
TLS3_k127_4261594_1	1237149.C900_04024	5.355e-90	304.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,47MWE@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
TLS3_k127_4261594_2	1237149.C900_04025	4.875e-62	221.0	2AEI8@1|root,331SH@2|Bacteria,4NWWM@976|Bacteroidetes,47S6K@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4281392_2	1237149.C900_01432	2.471e-206	649.0	COG0312@1|root,COG0312@2|Bacteria,4NE1F@976|Bacteroidetes,47N7M@768503|Cytophagia	976|Bacteroidetes	S	Peptidase U62 modulator of DNA gyrase	tldD3	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
TLS3_k127_4281392_1	411154.GFO_1941	3.493e-275	854.0	COG0312@1|root,COG0312@2|Bacteria,4NG2Y@976|Bacteroidetes,1HZ08@117743|Flavobacteriia	976|Bacteroidetes	S	and their inactivated homologs	tldD1	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
TLS3_k127_4281392_0	865937.Gilli_3256	3.426e-291	901.0	COG0312@1|root,COG0312@2|Bacteria,4NG2Y@976|Bacteroidetes,1HZ08@117743|Flavobacteriia,2P7EQ@244698|Gillisia	976|Bacteroidetes	S	Putative modulator of DNA gyrase	tldD1	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
TLS3_k127_4281392_3	929562.Emtol_2283	1.583e-164	519.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,47MHE@768503|Cytophagia	976|Bacteroidetes	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
TLS3_k127_4295815_2	493475.GARC_0682	2.042e-06	52.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,464U6@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
TLS3_k127_4295815_1	760192.Halhy_3568	9.884e-132	426.0	COG1082@1|root,COG1082@2|Bacteria,4PJ9G@976|Bacteroidetes,1IZP5@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
TLS3_k127_4295815_0	1408813.AYMG01000001_gene3481	1.44e-151	489.0	COG3177@1|root,COG3177@2|Bacteria,4NG08@976|Bacteroidetes,1IWB0@117747|Sphingobacteriia	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
TLS3_k127_4309456_1	1305836.AXVE01000011_gene1038	8.758e-40	151.0	2AEMC@1|root,314H9@2|Bacteria,1W0UA@1239|Firmicutes,4HRRY@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
TLS3_k127_4309456_0	153721.MYP_1594	1.88e-113	376.0	COG0457@1|root,COG0457@2|Bacteria,4NKK4@976|Bacteroidetes,47UDJ@768503|Cytophagia	976|Bacteroidetes	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
TLS3_k127_4317435_7	761193.Runsl_1906	3.753e-22	111.0	COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,47M8I@768503|Cytophagia	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4317435_10	1166018.FAES_4103	2.196e-08	64.0	28I8D@1|root,2ZBHJ@2|Bacteria,4NHI9@976|Bacteroidetes,47KUP@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
TLS3_k127_4317435_8	1123277.KB893239_gene1246	3.756e-12	71.0	28I8D@1|root,2ZBHJ@2|Bacteria,4NHI9@976|Bacteroidetes,47KUP@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
TLS3_k127_4317435_9	313606.M23134_02725	1.099e-10	66.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47K68@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_4317435_6	1166018.FAES_4103	1.201e-27	125.0	28I8D@1|root,2ZBHJ@2|Bacteria,4NHI9@976|Bacteroidetes,47KUP@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
TLS3_k127_4317435_2	926549.KI421517_gene2060	5.364e-198	647.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47JN3@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_4317435_3	153721.MYP_220	1.862e-178	564.0	COG2957@1|root,COG2957@2|Bacteria,4NGF8@976|Bacteroidetes,47KQQ@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the agmatine deiminase family	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
TLS3_k127_4317435_5	869213.JCM21142_93651	4.314e-48	175.0	COG0614@1|root,COG0614@2|Bacteria,4NR62@976|Bacteroidetes,47XUB@768503|Cytophagia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
TLS3_k127_4317435_4	700598.Niako_4382	9.73e-169	533.0	COG0388@1|root,COG0388@2|Bacteria,4NEME@976|Bacteroidetes,1IPIY@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	pabB	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
TLS3_k127_4317435_1	1237149.C900_01764	1.808e-222	698.0	COG0493@1|root,COG0493@2|Bacteria,4NG9R@976|Bacteroidetes,47M2V@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM glutamate synthases, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
TLS3_k127_4317435_0	1237149.C900_01765	0.0	2052.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,47JB7@768503|Cytophagia	976|Bacteroidetes	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
TLS3_k127_431834_5	1237149.C900_04768	3.786e-59	206.0	COG1366@1|root,COG1366@2|Bacteria,4NTPB@976|Bacteroidetes,47R1F@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
TLS3_k127_431834_1	1237149.C900_04767	1.302e-142	458.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,47JZR@768503|Cytophagia	976|Bacteroidetes	F	PFAM SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
TLS3_k127_431834_3	1237149.C900_01202	6.385e-112	376.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PSU@768503|Cytophagia	976|Bacteroidetes	S	PFAM MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_431834_0	1237149.C900_01203	4.82e-184	582.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,47JS8@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
TLS3_k127_431834_7	1237149.C900_01204	1.985e-54	201.0	COG4700@1|root,COG4700@2|Bacteria,4PPNH@976|Bacteroidetes,47YQ2@768503|Cytophagia	976|Bacteroidetes	T	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_431834_2	1237149.C900_01205	1.316e-115	382.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,47NJQ@768503|Cytophagia	976|Bacteroidetes	S	PFAM von Willebrand factor type A	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
TLS3_k127_431834_6	1124780.ANNU01000020_gene3311	6.737e-57	202.0	COG0454@1|root,COG0456@2|Bacteria,4NQVT@976|Bacteroidetes,47QAW@768503|Cytophagia	976|Bacteroidetes	K	PFAM GCN5-related N-acetyltransferase	paiA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
TLS3_k127_431834_8	1237149.C900_02524	6.227e-41	160.0	COG1538@1|root,COG1538@2|Bacteria,4NY7T@976|Bacteroidetes,47SZ0@768503|Cytophagia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_431834_9	926562.Oweho_3381	7.697e-27	114.0	COG0745@1|root,COG0745@2|Bacteria,4NSD3@976|Bacteroidetes,1I48M@117743|Flavobacteriia	976|Bacteroidetes	KT	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_431834_4	1124780.ANNU01000019_gene1768	4.991e-81	282.0	COG0318@1|root,COG0318@2|Bacteria,4NEXK@976|Bacteroidetes,47KUG@768503|Cytophagia	976|Bacteroidetes	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_431834_10	926549.KI421517_gene3815	3.12e-24	101.0	COG0447@1|root,COG0447@2|Bacteria,4NDXT@976|Bacteroidetes,47JYS@768503|Cytophagia	976|Bacteroidetes	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
TLS3_k127_4327769_2	643867.Ftrac_2626	2.899e-30	129.0	COG4251@1|root,COG4372@1|root,COG4251@2|Bacteria,COG4372@2|Bacteria,4NP5A@976|Bacteroidetes,47PX4@768503|Cytophagia	976|Bacteroidetes	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c
TLS3_k127_4327769_0	1237149.C900_03339	2.989e-57	206.0	COG0671@1|root,COG0671@2|Bacteria,4NNVQ@976|Bacteroidetes,47RBP@768503|Cytophagia	976|Bacteroidetes	I	PFAM PAP2 superfamily	ybjG	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
TLS3_k127_4327769_3	1123248.KB893348_gene100	1.475e-28	121.0	2B3U2@1|root,31WHV@2|Bacteria,4PJYJ@976|Bacteroidetes,1IYX3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4327769_1	1237149.C900_03338	1.645e-38	145.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,47TX8@768503|Cytophagia	976|Bacteroidetes	H	Lumazine binding domain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
TLS3_k127_4336304_0	4572.TRIUR3_33762-P1	4.455e-115	372.0	COG0057@1|root,KOG0657@2759|Eukaryota,37HSA@33090|Viridiplantae,3GEIW@35493|Streptophyta,3KST4@4447|Liliopsida,3I5JS@38820|Poales	35493|Streptophyta	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
TLS3_k127_4336304_4	1237149.C900_05163	7.047e-54	204.0	COG0484@1|root,COG4783@1|root,COG0484@2|Bacteria,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	ko:K21010	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	DUF560,DnaJ,Dynamin_N,Peptidase_M48,TPR_19,TPR_8
TLS3_k127_4336304_2	1237149.C900_00898	5.221e-79	273.0	2DGJB@1|root,32U7C@2|Bacteria,4NUFJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4336304_5	1121904.ARBP01000010_gene2374	4.004e-43	169.0	COG5492@1|root,COG5492@2|Bacteria,4PHVH@976|Bacteroidetes,47RH7@768503|Cytophagia	976|Bacteroidetes	N	Electron transfer DM13	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DM13
TLS3_k127_4336304_3	1237149.C900_00590	3.378e-56	201.0	COG4319@1|root,COG4319@2|Bacteria,4NNSF@976|Bacteroidetes	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
TLS3_k127_4336304_1	1237149.C900_00593	2.942e-91	302.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,47JJU@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS3_k127_433964_0	1237149.C900_04442	0.0	1719.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,47JTE@768503|Cytophagia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
TLS3_k127_433964_1	1237149.C900_04441	4.576e-96	320.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,47KR3@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
TLS3_k127_4342955_1	1123248.KB893370_gene5061	7.531e-39	150.0	COG3842@1|root,COG3842@2|Bacteria,4NEZ6@976|Bacteroidetes,1IQV7@117747|Sphingobacteriia	976|Bacteroidetes	E	ABC transporter	fbpC2	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
TLS3_k127_4342955_2	929703.KE386492_gene4388	1.101e-38	152.0	COG1309@1|root,COG1309@2|Bacteria,4NIBT@976|Bacteroidetes	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_4342955_0	471854.Dfer_0042	6.031e-109	363.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,47JA0@768503|Cytophagia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_4360030_0	1223410.KN050846_gene1375	1.388e-137	450.0	COG2373@1|root,COG2373@2|Bacteria,4P17V@976|Bacteroidetes	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4360030_1	700598.Niako_6535	8.34e-112	370.0	COG1647@1|root,COG1647@2|Bacteria,4NHPY@976|Bacteroidetes,1IQS4@117747|Sphingobacteriia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,BAAT_C,Hydrolase_4
TLS3_k127_4360030_2	1237149.C900_02213	8.152e-69	237.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,47M2Z@768503|Cytophagia	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
TLS3_k127_4362638_5	1237149.C900_04413	5.02e-72	248.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,47K5F@768503|Cytophagia	976|Bacteroidetes	Q	PFAM Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_4362638_4	1121904.ARBP01000012_gene1256	1.569e-95	343.0	COG2202@1|root,COG2203@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	rsbP	-	3.1.3.3	ko:K02660,ko:K07315,ko:K17763	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044,ko03021	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HD_5,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,STAS,SpoIIE
TLS3_k127_4362638_0	1239962.C943_00329	3.654e-200	631.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,47KB8@768503|Cytophagia	976|Bacteroidetes	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS3_k127_4362638_2	1237149.C900_04417	6.571e-131	437.0	COG0683@1|root,COG0683@2|Bacteria,4PKN8@976|Bacteroidetes,47NJW@768503|Cytophagia	976|Bacteroidetes	E	PFAM Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
TLS3_k127_4362638_1	1237149.C900_04418	1.543e-184	580.0	COG0519@1|root,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,47JG6@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
TLS3_k127_4365002_3	926551.KB900711_gene1792	1.315e-13	70.0	COG0346@1|root,COG0346@2|Bacteria,4NP3Y@976|Bacteroidetes,1I2G3@117743|Flavobacteriia,1ERVP@1016|Capnocytophaga	976|Bacteroidetes	E	Glyoxalase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
TLS3_k127_4365002_2	1239962.C943_02440	2.156e-24	107.0	COG3695@1|root,COG3695@2|Bacteria,4NZHS@976|Bacteroidetes	976|Bacteroidetes	L	enzyme binding	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
TLS3_k127_4365002_1	1297742.A176_07688	1.917e-49	181.0	COG3631@1|root,COG3631@2|Bacteria,1RDED@1224|Proteobacteria,43810@68525|delta/epsilon subdivisions,2X3B2@28221|Deltaproteobacteria,2YV6Y@29|Myxococcales	28221|Deltaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
TLS3_k127_4365002_0	1237149.C900_02070	3.935e-55	198.0	COG0727@1|root,COG0727@2|Bacteria,4NMJ0@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
TLS3_k127_4365002_4	1348583.ATLH01000009_gene3266	4.827e-09	65.0	2A47S@1|root,30SSZ@2|Bacteria,4PJBN@976|Bacteroidetes,1IMUK@117743|Flavobacteriia,1FADA@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_438503_2	929713.NIASO_07495	6.285e-21	93.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INWS@117747|Sphingobacteriia	976|Bacteroidetes	V	InterPro IPR003838	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_438503_3	153721.MYP_3679	5.399e-13	74.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_438503_0	926562.Oweho_3443	3.668e-130	430.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWWK@117743|Flavobacteriia,2PA7T@246874|Cryomorphaceae	976|Bacteroidetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_438503_1	909663.KI867150_gene970	7.003e-64	226.0	COG4191@1|root,COG4191@2|Bacteria,1R89N@1224|Proteobacteria,42QDX@68525|delta/epsilon subdivisions,2WKNA@28221|Deltaproteobacteria,2MR83@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS
TLS3_k127_4394243_1	1237149.C900_03796	1.05e-83	287.0	2BHR8@1|root,32BUM@2|Bacteria,4NR4P@976|Bacteroidetes,47QNP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4394243_3	1237149.C900_03796	4.497e-63	227.0	2BHR8@1|root,32BUM@2|Bacteria,4NR4P@976|Bacteroidetes,47QNP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4394243_0	1279009.ADICEAN_02496	1.979e-162	514.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,47K03@768503|Cytophagia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
TLS3_k127_4394243_2	1237149.C900_02945	4.429e-71	246.0	COG2340@1|root,COG2340@2|Bacteria,4NRNN@976|Bacteroidetes,47RRN@768503|Cytophagia	976|Bacteroidetes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
TLS3_k127_4394243_4	1313301.AUGC01000001_gene1409	1.692e-54	192.0	COG0538@1|root,COG0538@2|Bacteria,4PKW6@976|Bacteroidetes	976|Bacteroidetes	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
TLS3_k127_4408372_5	1121904.ARBP01000009_gene4289	1.792e-32	128.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,47MW1@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
TLS3_k127_4408372_6	1128421.JAGA01000002_gene1863	4.892e-16	80.0	2EFVT@1|root,339N0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Imp-YgjV
TLS3_k127_4408372_1	1121904.ARBP01000005_gene4607	2.124e-120	394.0	COG3386@1|root,COG3386@2|Bacteria,4NIMX@976|Bacteroidetes,47KMQ@768503|Cytophagia	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
TLS3_k127_4408372_3	1121904.ARBP01000011_gene1451	1.746e-53	197.0	29R44@1|root,30C5C@2|Bacteria,4NN15@976|Bacteroidetes,47PN2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4408372_2	1313421.JHBV01000005_gene4617	5.132e-63	223.0	COG1136@1|root,COG1136@2|Bacteria,4NNS2@976|Bacteroidetes,1IS7P@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_4408372_0	1121904.ARBP01000007_gene2978	1.16e-132	434.0	COG0577@1|root,COG0577@2|Bacteria,4NF60@976|Bacteroidetes,47KE0@768503|Cytophagia	976|Bacteroidetes	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_4408372_4	1239962.C943_03791	1.173e-37	146.0	COG3495@1|root,COG3495@2|Bacteria,4NMZ8@976|Bacteroidetes,47P8H@768503|Cytophagia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_441908_1	929703.KE386491_gene217	2.187e-44	165.0	COG4198@1|root,COG4198@2|Bacteria,4NGWT@976|Bacteroidetes,47MM8@768503|Cytophagia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
TLS3_k127_441908_0	1121957.ATVL01000008_gene4132	3.911e-226	708.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,47KFX@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 29	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
TLS3_k127_441908_4	1296415.JACC01000013_gene228	0.000123	48.0	2E4BN@1|root,32Z79@2|Bacteria,4NXNH@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_441908_2	1166018.FAES_4393	1.483e-31	132.0	COG1595@1|root,COG1595@2|Bacteria,4NKX6@976|Bacteroidetes,47KQJ@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_441908_3	204669.Acid345_3715	4.076e-11	68.0	COG2203@1|root,COG3283@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3283@2|Bacteria,COG4191@2|Bacteria,3Y3JK@57723|Acidobacteria,2JIZX@204432|Acidobacteriia	204432|Acidobacteriia	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
TLS3_k127_441908_5	28072.Nos7524_4790	0.0004005	46.0	COG0642@1|root,COG0745@1|root,COG2203@1|root,COG4251@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_4422743_3	761193.Runsl_5542	2.572e-19	87.0	COG3119@1|root,COG3119@2|Bacteria,4NGYE@976|Bacteroidetes,47MMC@768503|Cytophagia	976|Bacteroidetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TLS3_k127_4422743_0	1123276.KB893246_gene550	3.043e-244	767.0	COG2755@1|root,COG2755@2|Bacteria,4NEAZ@976|Bacteroidetes,47K65@768503|Cytophagia	976|Bacteroidetes	E	N-terminus of Esterase_SGNH_hydro-type	-	-	-	-	-	-	-	-	-	-	-	-	GxDLY,Lipase_GDSL_2,Lipase_GDSL_3
TLS3_k127_4422743_2	1123248.KB893325_gene1152	4.296e-201	632.0	COG1820@1|root,COG1820@2|Bacteria,4NJ35@976|Bacteroidetes,1IPWP@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
TLS3_k127_4422743_1	1123248.KB893325_gene1151	6.334e-238	742.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1IR81@117747|Sphingobacteriia	976|Bacteroidetes	G	glucose galactose transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_4422743_4	1550091.JROE01000011_gene3094	1.674e-06	49.0	COG0363@1|root,COG0363@2|Bacteria,4NFCM@976|Bacteroidetes,1IUZV@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
TLS3_k127_4425233_0	1121904.ARBP01000015_gene179	1.156e-133	451.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_4425233_1	760192.Halhy_2188	6.039e-23	104.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IVBV@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_443312_3	1249997.JHZW01000002_gene1688	6.418e-07	51.0	COG4251@1|root,COG4251@2|Bacteria,4NGXA@976|Bacteroidetes,1HY3D@117743|Flavobacteriia,2PI6M@252356|Maribacter	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS_3
TLS3_k127_443312_2	376686.Fjoh_3201	4.185e-33	134.0	COG0745@1|root,COG0745@2|Bacteria,4NXE8@976|Bacteroidetes,1IIY7@117743|Flavobacteriia,2NWJG@237|Flavobacterium	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_443312_4	1122128.AUEE01000012_gene64	0.0001022	49.0	COG4095@1|root,COG4095@2|Bacteria,1VF4D@1239|Firmicutes,4I0UK@91061|Bacilli	91061|Bacilli	S	PQ loop repeat	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	PQ-loop
TLS3_k127_443312_1	1123248.KB893317_gene4335	2.35e-34	137.0	COG1546@1|root,COG1546@2|Bacteria,4NVPM@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
TLS3_k127_443312_0	1122605.KB893643_gene591	5.403e-193	617.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,1IQI9@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
TLS3_k127_4435247_5	1123276.KB893245_gene1012	1.285e-33	131.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,47JG4@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
TLS3_k127_4435247_6	767031.HMPREF9137_2478	3.005e-12	66.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,2FM2B@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
TLS3_k127_4435247_1	1124780.ANNU01000037_gene144	1.196e-143	459.0	COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,47KZ9@768503|Cytophagia	976|Bacteroidetes	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_4435247_4	1124780.ANNU01000010_gene3645	3.601e-55	202.0	COG1512@1|root,COG1512@2|Bacteria	2|Bacteria	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4435247_3	1237149.C900_03683	1.02e-117	384.0	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,47MMI@768503|Cytophagia	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
TLS3_k127_4435247_0	1237149.C900_03684	1.391e-167	534.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,47JF2@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
TLS3_k127_4435247_2	1237149.C900_03685	3.627e-120	407.0	COG5002@1|root,COG5002@2|Bacteria,4PKMH@976|Bacteroidetes,47XWJ@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,PAS_4,PAS_9,TPR_12
TLS3_k127_4446499_0	1121904.ARBP01000002_gene6801	5.067e-225	710.0	COG2378@1|root,COG5285@1|root,COG2378@2|Bacteria,COG5285@2|Bacteria,4NGHM@976|Bacteroidetes,47MP3@768503|Cytophagia	976|Bacteroidetes	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	PhyH,WYL
TLS3_k127_4455916_2	1123248.KB893348_gene194	2.438e-108	377.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NJMF@976|Bacteroidetes,1IWR7@117747|Sphingobacteriia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
TLS3_k127_4455916_3	1122176.KB903561_gene3586	5.375e-49	181.0	COG2353@1|root,COG2353@2|Bacteria,4NI82@976|Bacteroidetes,1IXPV@117747|Sphingobacteriia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_4455916_1	1166018.FAES_1409	3.781e-123	400.0	COG1082@1|root,COG1082@2|Bacteria,4NFMD@976|Bacteroidetes,47JA9@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_4455916_0	388413.ALPR1_06265	7.437e-292	903.0	COG2303@1|root,COG2303@2|Bacteria,4NK1Z@976|Bacteroidetes,47NME@768503|Cytophagia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
TLS3_k127_4455916_4	761193.Runsl_0795	1.642e-37	147.0	2CDAN@1|root,309X8@2|Bacteria,4NRN2@976|Bacteroidetes,47QB3@768503|Cytophagia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
TLS3_k127_4455916_5	926559.JoomaDRAFT_3675	3.275e-30	124.0	COG0454@1|root,COG0456@2|Bacteria,4NHRI@976|Bacteroidetes,1I38S@117743|Flavobacteriia	976|Bacteroidetes	K	Transcriptional regulator, MarR family protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_4456995_2	1123248.KB893318_gene4093	4.991e-186	591.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IRBB@117747|Sphingobacteriia	976|Bacteroidetes	I	SPTR Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
TLS3_k127_4456995_4	1305737.JAFX01000001_gene2269	7.632e-54	206.0	28I8D@1|root,32Q7B@2|Bacteria,4PBP6@976|Bacteroidetes,47W40@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
TLS3_k127_4456995_1	1120965.AUBV01000003_gene468	1.725e-216	697.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_4456995_3	349161.Dred_2846	3.43e-104	344.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,248U5@186801|Clostridia,263ZF@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	iHN637.CLJU_RS07630	MIP
TLS3_k127_4456995_0	313603.FB2170_06875	1.582e-229	721.0	COG0554@1|root,COG0554@2|Bacteria,4NFUH@976|Bacteroidetes,1HX3Z@117743|Flavobacteriia,2PH7Y@252356|Maribacter	976|Bacteroidetes	C	FGGY family of carbohydrate kinases, C-terminal domain	glpK	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	DAO,DAO_C,FGGY_C,FGGY_N
TLS3_k127_4456995_5	1121875.KB907547_gene3294	1.772e-50	182.0	COG0578@1|root,COG0578@2|Bacteria,4PKIZ@976|Bacteroidetes	976|Bacteroidetes	C	Glycerol-3-phosphate dehydrogenase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
TLS3_k127_4464717_0	1237149.C900_01647	0.0	1035.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,47NAM@768503|Cytophagia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
TLS3_k127_4464717_1	1237149.C900_01650	2.97e-116	377.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,47MGR@768503|Cytophagia	976|Bacteroidetes	EF	Ribose-phosphate pyrophosphokinase	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
TLS3_k127_447058_4	1408433.JHXV01000028_gene2160	4.386e-12	66.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,1HXV5@117743|Flavobacteriia,2PARG@246874|Cryomorphaceae	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	1.1.3.48,2.7.7.38	ko:K00979,ko:K19714	ko00540,ko01100,map00540,map01100	M00063	R03351,R11394,R11396	RC00152,RC00910,RC03427	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
TLS3_k127_447058_0	1237149.C900_02212	5.705e-182	580.0	COG1030@1|root,COG1030@2|Bacteria,4NGGV@976|Bacteroidetes,47MQR@768503|Cytophagia	976|Bacteroidetes	O	Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,Peptidase_S49,SDH_sah
TLS3_k127_447058_3	153721.MYP_4280	1.122e-34	143.0	2DJDC@1|root,32UCS@2|Bacteria,4NTR3@976|Bacteroidetes,47RMX@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4905
TLS3_k127_447058_2	1237149.C900_02210	4.582e-84	290.0	COG1388@1|root,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,47NR5@768503|Cytophagia	976|Bacteroidetes	M	PFAM LysM domain	lysM	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
TLS3_k127_447058_1	1123248.KB893359_gene2071	6.932e-101	333.0	COG1432@1|root,COG1432@2|Bacteria,4NGF1@976|Bacteroidetes,1IRKK@117747|Sphingobacteriia	976|Bacteroidetes	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
TLS3_k127_4498713_1	107636.JQNK01000009_gene1300	3.697e-12	68.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,36ZK3@31993|Methylocystaceae	28211|Alphaproteobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
TLS3_k127_4498713_0	589865.DaAHT2_2072	0.0	1012.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2MHPT@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Elongation factor Tu domain 2	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
TLS3_k127_450332_3	929556.Solca_0604	5.068e-17	83.0	COG3325@1|root,COG3325@2|Bacteria,4NGAZ@976|Bacteroidetes,1IR7C@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 18 family	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
TLS3_k127_450332_1	926549.KI421517_gene1462	2.833e-222	706.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,47JCA@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
TLS3_k127_450332_0	1123073.KB899242_gene1193	1.174e-283	880.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria,1X4F1@135614|Xanthomonadales	135614|Xanthomonadales	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
TLS3_k127_450332_2	1123073.KB899241_gene3088	4.309e-59	211.0	2DPQD@1|root,332Z4@2|Bacteria,1R3FS@1224|Proteobacteria,1T67D@1236|Gammaproteobacteria,1X7FX@135614|Xanthomonadales	1224|Proteobacteria	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
TLS3_k127_4507259_1	1237149.C900_05577	1.205e-50	186.0	298PT@1|root,2ZVU7@2|Bacteria,4NPTP@976|Bacteroidetes,47RY6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4507259_0	313596.RB2501_05125	7.513e-252	785.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1HWJH@117743|Flavobacteriia	976|Bacteroidetes	S	X-Pro dipeptidyl-peptidase	cocE	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
TLS3_k127_4509600_1	1349822.NSB1T_05660	8.437e-152	487.0	COG2334@1|root,COG2334@2|Bacteria,4NH00@976|Bacteroidetes,2FKYD@200643|Bacteroidia,22XFX@171551|Porphyromonadaceae	976|Bacteroidetes	S	Phosphotransferase enzyme family	mdsC	-	-	-	-	-	-	-	-	-	-	-	APH
TLS3_k127_4509600_0	203275.BFO_1382	1.504e-176	563.0	COG3385@1|root,COG3385@2|Bacteria,4NXT2@976|Bacteroidetes,2FRVS@200643|Bacteroidia,2319R@171551|Porphyromonadaceae	976|Bacteroidetes	L	hmm pf01609	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
TLS3_k127_4509600_2	1250278.JQNQ01000001_gene2009	2.087e-17	85.0	COG2942@1|root,COG2942@2|Bacteria,4NEH7@976|Bacteroidetes,1HY0E@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
TLS3_k127_4519572_2	1237149.C900_05080	2.626e-42	156.0	COG1832@1|root,COG1832@2|Bacteria,4NSE8@976|Bacteroidetes,47RGM@768503|Cytophagia	976|Bacteroidetes	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
TLS3_k127_4519572_0	1123057.P872_10040	1.627e-220	694.0	COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,47K0W@768503|Cytophagia	976|Bacteroidetes	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2
TLS3_k127_4519572_1	1237149.C900_05078	5.006e-202	646.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47JEK@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_4519572_3	1237149.C900_05077	9.817e-34	132.0	COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,47KCQ@768503|Cytophagia	976|Bacteroidetes	E	Tryptophan 2,3-dioxygenase	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
TLS3_k127_4522762_2	1185876.BN8_03376	1.022e-59	215.0	2BSEF@1|root,32MGE@2|Bacteria,4NK41@976|Bacteroidetes,47USI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4522762_0	1185876.BN8_05813	1.088e-205	650.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,47ME9@768503|Cytophagia	976|Bacteroidetes	M	membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
TLS3_k127_4522762_1	1237149.C900_00082	2.201e-158	511.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia	976|Bacteroidetes	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_4522762_3	1237149.C900_04036	7.571e-12	70.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
TLS3_k127_4524100_0	1121904.ARBP01000015_gene179	3.342e-161	538.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_4525259_0	1392498.JQLH01000001_gene2569	6.161e-175	589.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1HZEZ@117743|Flavobacteriia,2PI0Z@252356|Maribacter	976|Bacteroidetes	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
TLS3_k127_454210_3	1356852.N008_04200	1.577e-23	111.0	COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,47NCY@768503|Cytophagia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
TLS3_k127_454210_0	760192.Halhy_5983	3.297e-215	680.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1IPND@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,Glyco_hydro_20,Glyco_hydro_20b
TLS3_k127_454210_2	761193.Runsl_1121	1.249e-107	353.0	COG4221@1|root,COG4221@2|Bacteria,4NFSY@976|Bacteroidetes,47KFB@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_454210_4	1120998.AUFC01000009_gene2133	5.117e-09	70.0	COG2911@1|root,COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3507@1|root,COG3533@1|root,COG4625@1|root,COG4733@1|root,COG5184@1|root,COG5492@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3507@2|Bacteria,COG3533@2|Bacteria,COG4625@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,24BEI@186801|Clostridia,3WDCT@538999|Clostridiales incertae sedis	1239|Firmicutes	U	S-layer homology domain	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Flg_new,SLH
TLS3_k127_454210_1	224911.27351823	4.734e-130	449.0	COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3209@1|root,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3JUXC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	MQ	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
TLS3_k127_4558719_2	1237149.C900_01672	9.453e-27	113.0	COG0457@1|root,COG4251@1|root,COG0457@2|Bacteria,COG4251@2|Bacteria,4P2V0@976|Bacteroidetes	976|Bacteroidetes	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,TPR_12,TPR_8
TLS3_k127_4558719_0	1237149.C900_01653	4.042e-306	953.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,47JB3@768503|Cytophagia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
TLS3_k127_4558719_1	929562.Emtol_2785	4.372e-27	119.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,47NAQ@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_4558719_3	1123278.KB893594_gene5879	9.505e-15	83.0	COG4585@1|root,COG4585@2|Bacteria,4NG0M@976|Bacteroidetes,47KNF@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	degS	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,PilJ
TLS3_k127_4565567_5	616991.JPOO01000001_gene3739	1.419e-72	258.0	COG0842@1|root,COG0842@2|Bacteria,4NGFA@976|Bacteroidetes,1HYPT@117743|Flavobacteriia	976|Bacteroidetes	V	Transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
TLS3_k127_4565567_7	575590.HMPREF0156_01329	2.34e-26	110.0	COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes	976|Bacteroidetes	IQ	acyl carrier protein	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TLS3_k127_4565567_3	485918.Cpin_6844	5.587e-136	443.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,1IRGP@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_4565567_4	616991.JPOO01000001_gene3733	4.196e-81	283.0	COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,1HXNF@117743|Flavobacteriia	976|Bacteroidetes	IQ	synthase	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
TLS3_k127_4565567_6	1123278.KB893545_gene4792	4.625e-59	220.0	28JIH@1|root,2Z9BT@2|Bacteria,4NIF7@976|Bacteroidetes,47SD9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999
TLS3_k127_4565567_1	485917.Phep_2975	2.546e-217	700.0	COG5373@1|root,COG5373@2|Bacteria,4NGKV@976|Bacteroidetes,1IP94@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
TLS3_k127_4565567_2	1123248.KB893348_gene329	8.564e-139	449.0	COG3394@1|root,COG3394@2|Bacteria,4NFY5@976|Bacteroidetes,1IVCK@117747|Sphingobacteriia	976|Bacteroidetes	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
TLS3_k127_4565567_0	1237149.C900_04538	0.0	1443.0	28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,47M2D@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4568602_1	1123277.KB893203_gene6263	3.186e-89	296.0	COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes,47N88@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
TLS3_k127_4568602_0	1237149.C900_05664	8.215e-282	869.0	COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,47JZJ@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM FeS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
TLS3_k127_4568602_2	1237149.C900_05665	1.628e-73	250.0	COG1522@1|root,COG1522@2|Bacteria,4NHG9@976|Bacteroidetes,47PXD@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix ASNC type	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
TLS3_k127_4572205_2	269798.CHU_3122	7.607e-13	68.0	COG0484@1|root,COG0484@2|Bacteria,4NME2@976|Bacteroidetes,47RGP@768503|Cytophagia	976|Bacteroidetes	O	KTSC domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,KTSC
TLS3_k127_4572205_1	1123057.P872_02720	9.094e-77	276.0	COG0845@1|root,COG0845@2|Bacteria,4NI7Q@976|Bacteroidetes,47JYK@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4572205_0	700598.Niako_0709	4.795e-257	801.0	COG3534@1|root,COG3534@2|Bacteria,4NECK@976|Bacteroidetes,1IP52@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase domain protein	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
TLS3_k127_4573322_9	929556.Solca_0435	2.846e-12	72.0	2BWZA@1|root,32RGQ@2|Bacteria,4NQBI@976|Bacteroidetes,1ITP6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4573322_2	1121929.KB898666_gene2572	2.818e-56	202.0	COG1073@1|root,COG1073@2|Bacteria,1V7CZ@1239|Firmicutes,4HJJ0@91061|Bacilli	91061|Bacilli	S	Serine hydrolase	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
TLS3_k127_4573322_8	714943.Mucpa_6548	1.701e-14	77.0	COG0500@1|root,COG0500@2|Bacteria,4NVGC@976|Bacteroidetes,1IU64@117747|Sphingobacteriia	976|Bacteroidetes	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4573322_1	761193.Runsl_0545	1.852e-61	215.0	COG2764@1|root,COG2764@2|Bacteria,4NQD7@976|Bacteroidetes,47QQP@768503|Cytophagia	976|Bacteroidetes	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
TLS3_k127_4573322_10	649349.Lbys_1034	0.0001147	45.0	COG3607@1|root,COG3607@2|Bacteria,4NRTG@976|Bacteroidetes,47XTH@768503|Cytophagia	976|Bacteroidetes	S	Glyoxalase-like domain	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS3_k127_4573322_6	1121373.KB903624_gene2433	4.104e-50	180.0	COG0640@1|root,COG0640@2|Bacteria,4NSDX@976|Bacteroidetes,47R1P@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
TLS3_k127_4573322_5	1237149.C900_05570	5.524e-51	186.0	COG3832@1|root,COG3832@2|Bacteria,4NST9@976|Bacteroidetes,47R8V@768503|Cytophagia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_4573322_4	1123248.KB893317_gene4274	6.352e-54	192.0	COG3832@1|root,COG3832@2|Bacteria,4NST9@976|Bacteroidetes,1ISQV@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_4573322_3	1089551.KE386572_gene1220	2.146e-55	205.0	COG2040@1|root,COG2040@2|Bacteria,1MUXU@1224|Proteobacteria,2TURU@28211|Alphaproteobacteria,4BRK0@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Homocysteine S-methyltransferase	-	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
TLS3_k127_4573322_0	886377.Murru_3014	2.96e-109	359.0	COG3000@1|root,COG3000@2|Bacteria,4NI62@976|Bacteroidetes,1I9FZ@117743|Flavobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
TLS3_k127_4573322_7	1250232.JQNJ01000001_gene3217	4.511e-43	162.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	pelC	-	-	ko:K21008	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	LpoB
TLS3_k127_4581582_0	1123277.KB893201_gene6422	2.499e-180	583.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_4581582_1	700598.Niako_1577	2.047e-49	194.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,1IQI9@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
TLS3_k127_4581582_2	1121904.ARBP01000003_gene6147	6.753e-28	120.0	COG1595@1|root,COG1595@2|Bacteria,4NKX6@976|Bacteroidetes,47KQJ@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_45853_0	1121859.KB890756_gene1450	6.405e-160	510.0	COG2188@1|root,COG2188@2|Bacteria,4PMHY@976|Bacteroidetes,47YD4@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_3
TLS3_k127_45853_1	558152.IQ37_05115	2.318e-42	163.0	COG1285@1|root,COG1285@2|Bacteria,4NRHK@976|Bacteroidetes,1IGRC@117743|Flavobacteriia,3ZT2T@59732|Chryseobacterium	976|Bacteroidetes	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
TLS3_k127_4588897_0	1237149.C900_05635	0.0	1281.0	COG1629@1|root,COG1629@2|Bacteria,4PKAS@976|Bacteroidetes,47YAG@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_4588897_1	760192.Halhy_2145	1.339e-137	456.0	COG0521@1|root,COG0521@2|Bacteria,4NFT1@976|Bacteroidetes,1IS6R@117747|Sphingobacteriia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_2
TLS3_k127_4588897_2	760192.Halhy_2146	1.562e-09	63.0	2DG20@1|root,2ZU4Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_460310_1	153721.MYP_1441	1.28e-118	390.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,47JBE@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
TLS3_k127_460310_0	1237149.C900_01083	2.051e-158	508.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,47KMP@768503|Cytophagia	976|Bacteroidetes	E	PFAM Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
TLS3_k127_4606070_3	929703.KE386491_gene4106	1.016e-29	119.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,47JHC@768503|Cytophagia	976|Bacteroidetes	F	Orotidine 5''-phosphate decarboxylase	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
TLS3_k127_4606070_2	1237149.C900_03780	1.142e-66	233.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,47PRT@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
TLS3_k127_4606070_0	1305737.JAFX01000001_gene2146	8.349e-307	962.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,47JI0@768503|Cytophagia	976|Bacteroidetes	D	DNA segregation ATPase FtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
TLS3_k127_4606070_1	700598.Niako_3302	8.541e-92	323.0	COG1520@1|root,COG1520@2|Bacteria	700598.Niako_3302|-	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_460761_1	1239962.C943_03737	8.4e-130	421.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47J95@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TLS3_k127_460761_0	1239962.C943_03733	2.824e-199	634.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,4P3P6@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_460761_4	388413.ALPR1_11430	2.482e-41	155.0	COG1695@1|root,COG1695@2|Bacteria,4NTYF@976|Bacteroidetes,47R1G@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_460761_3	1121904.ARBP01000013_gene426	1.203e-60	214.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NE2@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_4613129_2	760192.Halhy_2280	5.396e-95	321.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4PIZU@976|Bacteroidetes,1IYUX@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TLS3_k127_4613129_0	1237149.C900_04147	1.619e-299	940.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,47KXK@768503|Cytophagia	976|Bacteroidetes	G	PFAM GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TLS3_k127_4613129_1	926549.KI421517_gene2982	8.514e-160	514.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,47K2R@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yidK	-	-	-	-	-	-	-	-	-	-	-	SSF
TLS3_k127_461773_2	1288963.ADIS_0218	3.457e-62	221.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,47NI9@768503|Cytophagia	976|Bacteroidetes	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
TLS3_k127_461773_0	929562.Emtol_3103	2.195e-156	504.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,47JIU@768503|Cytophagia	976|Bacteroidetes	P	Na H antiporter NhaD and related arsenite	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
TLS3_k127_461773_1	1237149.C900_03255	1.438e-150	486.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,47KM0@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
TLS3_k127_4619721_1	1237149.C900_01141	2.083e-105	353.0	COG4324@1|root,COG4324@2|Bacteria,4NF0V@976|Bacteroidetes,47NVX@768503|Cytophagia	976|Bacteroidetes	I	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
TLS3_k127_4619721_0	1237149.C900_01143	3.051e-121	391.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,47MJ5@768503|Cytophagia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_4619721_2	1124780.ANNU01000043_gene342	1.26e-11	67.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,47JX1@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_463677_1	1237149.C900_04621	1.343e-90	304.0	COG0861@1|root,COG0861@2|Bacteria,4NH7P@976|Bacteroidetes,47N45@768503|Cytophagia	976|Bacteroidetes	P	PFAM Integral membrane protein TerC	ygjT	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
TLS3_k127_463677_2	1185876.BN8_05959	2.02e-48	176.0	COG0735@1|root,COG0735@2|Bacteria,4NSES@976|Bacteroidetes,47PU3@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the Fur family	zur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
TLS3_k127_463677_0	1237149.C900_04623	3.965e-224	707.0	COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,47M5S@768503|Cytophagia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
TLS3_k127_4639702_2	886377.Murru_3303	1.461e-49	181.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1HYSX@117743|Flavobacteriia	976|Bacteroidetes	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
TLS3_k127_4639702_1	929703.KE386491_gene3018	1.2e-77	267.0	COG0500@1|root,COG2226@2|Bacteria,4NG68@976|Bacteroidetes,47NYV@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_4639702_0	526227.Mesil_0745	6.314e-99	329.0	COG0010@1|root,COG0010@2|Bacteria,1WIEY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the arginase family	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS3_k127_4639702_3	1303518.CCALI_02909	8.529e-47	171.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ytaP	-	-	-	-	-	-	-	-	-	-	-	AXE1,Abhydrolase_7,DLH,Peptidase_S15,Peptidase_S9
TLS3_k127_4648857_2	1408473.JHXO01000009_gene3310	9.941e-79	277.0	COG0612@1|root,COG0612@2|Bacteria,4NHQP@976|Bacteroidetes	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_4648857_1	926556.Echvi_1915	2.379e-86	294.0	COG0561@1|root,COG0561@2|Bacteria,4NICE@976|Bacteroidetes,47P96@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
TLS3_k127_4648857_0	1122915.AUGY01000002_gene7445	6.558e-138	445.0	COG0451@1|root,COG0451@2|Bacteria,1TPHV@1239|Firmicutes,4HCJR@91061|Bacilli,26SNR@186822|Paenibacillaceae	91061|Bacilli	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS3_k127_465450_1	1121875.KB907547_gene3381	1.547e-142	466.0	COG1288@1|root,COG1288@2|Bacteria,4NEUI@976|Bacteroidetes,1HYKQ@117743|Flavobacteriia	976|Bacteroidetes	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
TLS3_k127_465450_2	1196029.ALIM01000023_gene505	3.832e-130	428.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4HD8E@91061|Bacilli,1ZAWS@1386|Bacillus	91061|Bacilli	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	yodT	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
TLS3_k127_465450_3	1340434.AXVA01000016_gene766	2.085e-91	306.0	COG1788@1|root,COG1788@2|Bacteria,1TSZT@1239|Firmicutes,4HDJG@91061|Bacilli,1ZQEH@1386|Bacillus	91061|Bacilli	I	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	atoD	-	2.8.3.8,2.8.3.9	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
TLS3_k127_465450_4	1034347.CAHJ01000019_gene3399	6.214e-73	251.0	COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,4HB5T@91061|Bacilli,1ZQEG@1386|Bacillus	91061|Bacilli	I	CoA-transferase	-	-	2.8.3.8,2.8.3.9	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
TLS3_k127_465450_0	649747.HMPREF0083_02918	2.07e-165	530.0	COG0624@1|root,COG0624@2|Bacteria,1TQS9@1239|Firmicutes,4HDHW@91061|Bacilli,26UDI@186822|Paenibacillaceae	91061|Bacilli	E	Peptidase family M20/M25/M40	yodQ	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_465450_5	666686.B1NLA3E_14065	3.049e-45	172.0	COG0454@1|root,COG0456@2|Bacteria,1V4AF@1239|Firmicutes,4HI6U@91061|Bacilli,1ZQJE@1386|Bacillus	91061|Bacilli	K	Acetyltransferase (GNAT) family	-	-	2.3.1.264	ko:K21935	-	-	R11701	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_9
TLS3_k127_4657563_1	1237149.C900_00062	2.985e-202	637.0	COG1131@1|root,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,47KQD@768503|Cytophagia	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,TerB
TLS3_k127_4657563_0	1237149.C900_00028	5.611e-260	817.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,47KAN@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
TLS3_k127_4657563_2	1237149.C900_00026	1.796e-101	338.0	COG1512@1|root,COG1512@2|Bacteria	2|Bacteria	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4657707_4	1237149.C900_03182	9.479e-17	83.0	COG1472@1|root,COG1472@2|Bacteria,4NET8@976|Bacteroidetes,47P5P@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
TLS3_k127_4657707_0	1123234.AUKI01000019_gene365	5.111e-124	410.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1HY7E@117743|Flavobacteriia	976|Bacteroidetes	M	D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
TLS3_k127_4657707_2	1237149.C900_03184	1.148e-55	199.0	COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,47PR7@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_4657707_1	1237149.C900_01523	2.033e-91	307.0	28IIU@1|root,2Z8JV@2|Bacteria,4NEFH@976|Bacteroidetes,47JU3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4657707_3	1237149.C900_04535	2.12e-25	106.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,47JUE@768503|Cytophagia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
TLS3_k127_4665588_1	1124780.ANNU01000024_gene3120	2.61e-160	511.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,47KEP@768503|Cytophagia	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
TLS3_k127_4665588_2	1237149.C900_02233	7.929e-159	514.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,47KTX@768503|Cytophagia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
TLS3_k127_4665588_0	1237149.C900_02232	3.75e-191	602.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,47K3R@768503|Cytophagia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
TLS3_k127_4665588_3	1237149.C900_02231	2.069e-152	489.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,47JXF@768503|Cytophagia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
TLS3_k127_4666269_1	1123057.P872_16510	6.316e-49	184.0	2DBXN@1|root,2ZBQR@2|Bacteria,4NN54@976|Bacteroidetes,47PK0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_4666269_0	1237149.C900_02054	1.625e-317	982.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,47YDB@768503|Cytophagia	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
TLS3_k127_4675455_0	926549.KI421517_gene3797	5.628e-116	377.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,47KXT@768503|Cytophagia	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
TLS3_k127_4675455_2	1279009.ADICEAN_01405	1.408e-106	351.0	COG1583@1|root,COG1583@2|Bacteria,4NJ54@976|Bacteroidetes,47MMT@768503|Cytophagia	976|Bacteroidetes	L	PFAM CRISPR associated protein Cas6	-	-	-	ko:K19091	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas6
TLS3_k127_4675455_1	1237149.C900_02464	1.389e-112	377.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,47MAE@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
TLS3_k127_4675455_4	1121904.ARBP01000006_gene3957	1.721e-60	214.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,47QG6@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_4675455_5	1121904.ARBP01000006_gene3956	1.182e-30	138.0	COG3170@1|root,COG3170@2|Bacteria,4PNAZ@976|Bacteroidetes,47NCV@768503|Cytophagia	976|Bacteroidetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_4675455_3	1237149.C900_02467	1.609e-65	233.0	COG5276@1|root,COG5276@2|Bacteria,4NG4W@976|Bacteroidetes,47K9R@768503|Cytophagia	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
TLS3_k127_4678173_0	925409.KI911562_gene2328	1.185e-165	537.0	28K2T@1|root,2Z9S3@2|Bacteria,4NJHU@976|Bacteroidetes	976|Bacteroidetes	S	SusD family	-	-	-	-	-	-	-	-	-	-	-	-	SusD_RagB
TLS3_k127_4678173_2	1123278.KB893549_gene5120	2.482e-95	321.0	COG2378@1|root,COG2378@2|Bacteria,4NHIC@976|Bacteroidetes,47K9W@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
TLS3_k127_4678173_3	929703.KE386491_gene3958	3.722e-60	213.0	COG0727@1|root,COG0727@2|Bacteria,4NJH9@976|Bacteroidetes,47QHT@768503|Cytophagia	976|Bacteroidetes	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
TLS3_k127_4678173_4	1237149.C900_03646	2.014e-57	200.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,47QDT@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
TLS3_k127_4678173_1	1237149.C900_03657	2.443e-119	391.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,47K9H@768503|Cytophagia	976|Bacteroidetes	L	DNA-directed DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
TLS3_k127_4686451_5	1123277.KB893172_gene566	5.283e-52	192.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47M0S@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_4686451_0	1123248.KB893386_gene1917	2.643e-318	995.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1IR88@117747|Sphingobacteriia	976|Bacteroidetes	P	TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
TLS3_k127_4686451_3	383372.Rcas_4299	2.126e-82	284.0	COG0530@1|root,COG0530@2|Bacteria,2G7I2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
TLS3_k127_4686451_8	865937.Gilli_3239	4.852e-21	97.0	2CYW5@1|root,32T50@2|Bacteria,4NS73@976|Bacteroidetes,1I3WS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4686451_2	1121373.KB903654_gene1676	7.18e-86	288.0	COG3448@1|root,COG3448@2|Bacteria,4NMHI@976|Bacteroidetes,47P6M@768503|Cytophagia	976|Bacteroidetes	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
TLS3_k127_4686451_4	1168034.FH5T_19660	7.097e-59	211.0	2BNB7@1|root,32GYU@2|Bacteria,4NQDS@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4686451_7	1121373.KB903663_gene1208	6.363e-34	137.0	COG1595@1|root,COG1595@2|Bacteria,4NTGC@976|Bacteroidetes,47RB8@768503|Cytophagia	976|Bacteroidetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
TLS3_k127_4686451_6	1121373.KB903663_gene1209	2.355e-49	181.0	COG1225@1|root,COG1225@2|Bacteria,4NWGT@976|Bacteroidetes,47X54@768503|Cytophagia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TLS3_k127_4686451_1	1185876.BN8_04288	8.276e-154	494.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,47Y2J@768503|Cytophagia	976|Bacteroidetes	H	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_4688979_2	269798.CHU_3722	4.403e-42	159.0	COG2137@1|root,COG2137@2|Bacteria,4NSAS@976|Bacteroidetes,47QBK@768503|Cytophagia	976|Bacteroidetes	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
TLS3_k127_4688979_3	1121890.AUDO01000003_gene1978	2.879e-38	153.0	2E945@1|root,333D0@2|Bacteria,4NVPT@976|Bacteroidetes,1IBY3@117743|Flavobacteriia,2NXH3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4688979_1	643867.Ftrac_2827	9.965e-64	222.0	COG2077@1|root,COG2077@2|Bacteria,4NNGR@976|Bacteroidetes,47RNU@768503|Cytophagia	976|Bacteroidetes	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
TLS3_k127_4688979_0	1237149.C900_03155	0.0	1047.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47KZ0@768503|Cytophagia	976|Bacteroidetes	E	PFAM Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
TLS3_k127_4688979_4	1313301.AUGC01000008_gene462	6.757e-11	65.0	2DNSC@1|root,32YWT@2|Bacteria,4NVHW@976|Bacteroidetes	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_4690287_0	1121287.AUMU01000011_gene665	6.06e-190	617.0	COG0793@1|root,COG0793@2|Bacteria,4NEK8@976|Bacteroidetes,1HYIK@117743|Flavobacteriia,3ZPH1@59732|Chryseobacterium	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
TLS3_k127_4712797_0	866536.Belba_3542	8.721e-135	465.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,47JK3@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Reg_prop,Response_reg,Y_Y_Y
TLS3_k127_4712797_1	1237149.C900_01538	7.213e-27	114.0	COG0745@1|root,COG0745@2|Bacteria	1237149.C900_01538|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_471578_1	553177.CAPSP0001_0972	1.477e-69	244.0	COG1376@1|root,COG1376@2|Bacteria,4NNX7@976|Bacteroidetes,1I2D3@117743|Flavobacteriia,1ERGZ@1016|Capnocytophaga	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
TLS3_k127_471578_0	926551.KB900709_gene1111	4.058e-107	369.0	COG2989@1|root,COG2989@2|Bacteria,4NH3J@976|Bacteroidetes,1I08J@117743|Flavobacteriia,1EQ7S@1016|Capnocytophaga	976|Bacteroidetes	S	peptidoglycan binding domain protein	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
TLS3_k127_471578_2	1237149.C900_02065	1.776e-15	86.0	2EJ5R@1|root,33CWY@2|Bacteria,4NYJK@976|Bacteroidetes,47SY4@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4717255_0	313606.M23134_05475	0.0	1087.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47MEM@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
TLS3_k127_4719152_0	1237149.C900_05247	8.523e-246	797.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,47JE0@768503|Cytophagia	976|Bacteroidetes	M	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
TLS3_k127_4719152_1	1237149.C900_05248	3.977e-59	215.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,47KRB@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
TLS3_k127_4721988_0	1121904.ARBP01000002_gene6983	6.557e-167	548.0	COG4206@1|root,COG4206@2|Bacteria,4PKF2@976|Bacteroidetes,47JDS@768503|Cytophagia	976|Bacteroidetes	H	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_4721988_1	1237149.C900_00803	3.331e-50	185.0	29TMV@1|root,30EVG@2|Bacteria,4NNPM@976|Bacteroidetes,47RB5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4721988_2	1048983.EL17_04725	1.13e-36	144.0	COG3495@1|root,COG3495@2|Bacteria,4NMZ8@976|Bacteroidetes,47P8H@768503|Cytophagia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4721988_3	761193.Runsl_1867	0.0003381	48.0	2C95D@1|root,3375K@2|Bacteria,4NX8T@976|Bacteroidetes,47SI2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4723681_3	1185876.BN8_01322	8.005e-116	376.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,47JMW@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
TLS3_k127_4723681_2	1123248.KB893386_gene1976	2.759e-136	440.0	COG1052@1|root,COG1052@2|Bacteria,4NF1R@976|Bacteroidetes,1IRC8@117747|Sphingobacteriia	976|Bacteroidetes	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TLS3_k127_4723681_1	1237149.C900_02756	8.113e-180	582.0	COG1629@1|root,COG1629@2|Bacteria,4PM72@976|Bacteroidetes,47Y3N@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,DUF4139,DUF4140,Plug
TLS3_k127_4723681_4	1237149.C900_02856	5.88e-92	308.0	COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,47JZC@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
TLS3_k127_4723681_6	1237149.C900_01730	4.289e-27	111.0	COG2154@1|root,COG2154@2|Bacteria,4NS9U@976|Bacteroidetes,47RW0@768503|Cytophagia	976|Bacteroidetes	H	PFAM Pterin 4 alpha carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
TLS3_k127_4723681_5	1237149.C900_01728	1.763e-27	115.0	COG2921@1|root,COG2921@2|Bacteria,4P9XR@976|Bacteroidetes,47S9P@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF493)	-	-	-	-	-	-	-	-	-	-	-	-	DUF493
TLS3_k127_4723681_0	1237149.C900_01727	2.153e-194	623.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,47KBN@768503|Cytophagia	976|Bacteroidetes	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
TLS3_k127_4728807_2	153721.MYP_1360	8.553e-29	131.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4P1M1@976|Bacteroidetes,47U02@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
TLS3_k127_4728807_1	1538644.KO02_06755	2.901e-70	242.0	COG0262@1|root,COG0262@2|Bacteria,4NPM3@976|Bacteroidetes,1IT7M@117747|Sphingobacteriia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
TLS3_k127_4728807_0	1270196.JCKI01000003_gene2003	2.784e-144	465.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1IP1X@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
TLS3_k127_4731939_0	1237149.C900_05890	6.752e-199	650.0	COG3291@1|root,COG3291@2|Bacteria,4NDU9@976|Bacteroidetes,47MS8@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_4731939_1	1124780.ANNU01000019_gene1687	3.446e-64	225.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,47KB6@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
TLS3_k127_4734855_1	1089547.KB913013_gene3352	1.212e-115	377.0	2DBBU@1|root,2Z8AF@2|Bacteria,4NFUM@976|Bacteroidetes,47JIC@768503|Cytophagia	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_4734855_2	395961.Cyan7425_2192	4.098e-86	292.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
TLS3_k127_4734855_0	1121957.ATVL01000008_gene4299	7.008e-125	408.0	COG0707@1|root,COG0707@2|Bacteria,4PKSS@976|Bacteroidetes,47NVZ@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_3
TLS3_k127_4734855_3	869213.JCM21142_73072	7.814e-14	80.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
TLS3_k127_4740325_2	700598.Niako_2476	9.981e-70	251.0	COG0729@1|root,COG0729@2|Bacteria,4PMQ2@976|Bacteroidetes,1J0MU@117747|Sphingobacteriia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
TLS3_k127_4740325_0	1185876.BN8_05299	8.657e-122	397.0	2DBR4@1|root,2ZAI1@2|Bacteria,4NTEE@976|Bacteroidetes,47UF4@768503|Cytophagia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_4740325_1	1239962.C943_02029	2.197e-113	374.0	COG5297@1|root,COG5297@2|Bacteria,4NG19@976|Bacteroidetes	976|Bacteroidetes	G	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1593,DUF5060
TLS3_k127_4740325_3	269798.CHU_3527	1.037e-62	219.0	COG4682@1|root,COG4682@2|Bacteria,4NPA4@976|Bacteroidetes,47Q4P@768503|Cytophagia	976|Bacteroidetes	S	yiaA/B two helix domain	yiaA	-	-	-	-	-	-	-	-	-	-	-	YiaAB
TLS3_k127_4749343_1	1124780.ANNU01000024_gene3036	1.124e-179	565.0	COG0502@1|root,COG0502@2|Bacteria,4NEMA@976|Bacteroidetes,47K22@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
TLS3_k127_4749343_0	1237149.C900_00949	2.859e-188	604.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,47KQH@768503|Cytophagia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
TLS3_k127_4749343_3	468059.AUHA01000003_gene1429	3.603e-48	177.0	COG0801@1|root,COG0801@2|Bacteria,4NGE8@976|Bacteroidetes,1ISW1@117747|Sphingobacteriia	976|Bacteroidetes	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
TLS3_k127_4749343_2	1237149.C900_00952	7.621e-143	457.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,47JDE@768503|Cytophagia	976|Bacteroidetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
TLS3_k127_4749343_4	518766.Rmar_1681	1.967e-23	101.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,1FK8C@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
TLS3_k127_4756804_0	1121904.ARBP01000030_gene1964	8.871e-168	541.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47MYR@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_4756804_2	1237149.C900_03951	1.525e-44	165.0	COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QWB@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_4756804_1	1537994.JQFW01000056_gene798	6.502e-123	415.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1RQGQ@1236|Gammaproteobacteria,46CR9@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_4756804_3	1499967.BAYZ01000123_gene2524	1.185e-13	82.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	MA20_22505	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
TLS3_k127_4760445_2	641143.HMPREF9331_01172	0.0001903	51.0	2DRR3@1|root,33CQA@2|Bacteria,4NY3S@976|Bacteroidetes,1IEV3@117743|Flavobacteriia,1ER7X@1016|Capnocytophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4760445_0	1237149.C900_02611	5.644e-150	479.0	COG1028@1|root,COG1028@2|Bacteria,4NE45@976|Bacteroidetes,47JX5@768503|Cytophagia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase SDR	ykuF	-	-	ko:K13774	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short_C2
TLS3_k127_4760445_1	1237149.C900_02609	4.889e-54	195.0	COG0156@1|root,COG0156@2|Bacteria,4NEXI@976|Bacteroidetes,47MTG@768503|Cytophagia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_4760666_1	1237149.C900_03330	7.038e-116	374.0	COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,47JH6@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0176 family	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
TLS3_k127_4760666_2	1237149.C900_03329	6.582e-90	298.0	COG0521@1|root,COG0521@2|Bacteria,4PIS5@976|Bacteroidetes,47KA4@768503|Cytophagia	976|Bacteroidetes	H	Probable molybdopterin binding domain	-	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
TLS3_k127_4760666_0	1237149.C900_03328	1.433e-142	457.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,47NA5@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_4761075_0	1237149.C900_03232	1.312e-199	623.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,47JWD@768503|Cytophagia	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
TLS3_k127_4761075_2	1237149.C900_04583	2.499e-47	172.0	2D41J@1|root,32TG2@2|Bacteria,4NTNX@976|Bacteroidetes,47RJ7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4761075_1	313606.M23134_02537	7.344e-131	427.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,47JXR@768503|Cytophagia	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
TLS3_k127_4774684_1	1237149.C900_05865	3.499e-46	180.0	28KQM@1|root,2ZA8D@2|Bacteria,4NH80@976|Bacteroidetes,47JWY@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4774684_0	1237149.C900_05864	8.176e-132	437.0	28KQM@1|root,2ZA8D@2|Bacteria,4NH80@976|Bacteroidetes,47JWY@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4775260_1	1120965.AUBV01000003_gene598	3.093e-68	233.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,47MD1@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
TLS3_k127_4775260_5	237368.SCABRO_00945	1.655e-17	86.0	COG4634@1|root,COG4634@2|Bacteria,2J4DQ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4775260_4	1123278.KB893548_gene4728	5.042e-21	94.0	COG2442@1|root,COG2442@2|Bacteria,4NZ3D@976|Bacteroidetes,47X60@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
TLS3_k127_4775260_2	1121904.ARBP01000002_gene6990	9.226e-67	233.0	COG0637@1|root,COG0637@2|Bacteria,4NEEH@976|Bacteroidetes,47XKJ@768503|Cytophagia	976|Bacteroidetes	S	HAD-hyrolase-like	pgmB	-	-	-	-	-	-	-	-	-	-	-	HAD_2
TLS3_k127_4775260_0	643867.Ftrac_3122	4.671e-115	376.0	COG0500@1|root,COG2226@2|Bacteria,4NE6P@976|Bacteroidetes,47K6K@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	rebM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_4775260_3	313606.M23134_08314	2.757e-61	218.0	COG1595@1|root,COG1595@2|Bacteria,4NU4K@976|Bacteroidetes,47UQA@768503|Cytophagia	976|Bacteroidetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_4775439_2	1121931.AUHG01000010_gene95	1.597e-11	66.0	2DRCR@1|root,33B8F@2|Bacteria,4NUWN@976|Bacteroidetes,1I5E0@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4174)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4174
TLS3_k127_4775439_1	1008457.BAEX01000128_gene452	1.752e-76	268.0	COG4974@1|root,COG4974@2|Bacteria,4NGB5@976|Bacteroidetes,1HXP1@117743|Flavobacteriia	976|Bacteroidetes	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
TLS3_k127_4775439_0	929562.Emtol_0946	1.526e-88	298.0	COG5507@1|root,COG5507@2|Bacteria,4NJE8@976|Bacteroidetes,47NID@768503|Cytophagia	976|Bacteroidetes	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
TLS3_k127_4789678_4	1237149.C900_04340	7.941e-24	101.0	COG1266@1|root,COG1266@2|Bacteria,4NJAV@976|Bacteroidetes,47M12@768503|Cytophagia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
TLS3_k127_4789678_2	1124780.ANNU01000075_gene835	1.076e-110	369.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,47MBB@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_4789678_3	906888.JCM19314_1965	1.643e-66	231.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,1HX3R@117743|Flavobacteriia,3HJJI@363408|Nonlabens	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
TLS3_k127_4789678_0	1237149.C900_04333	2.019e-158	512.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,47JF4@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
TLS3_k127_4789678_1	1237149.C900_04332	5.442e-111	369.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,47M95@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
TLS3_k127_4792942_1	1237149.C900_00894	1.096e-127	416.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47JJM@768503|Cytophagia	976|Bacteroidetes	MU	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
TLS3_k127_4792942_0	1237149.C900_01855	6.494e-137	438.0	COG1398@1|root,COG1398@2|Bacteria,4NE0I@976|Bacteroidetes,47KJ0@768503|Cytophagia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_4792942_2	1237149.C900_01856	1.07e-57	207.0	COG1595@1|root,COG1595@2|Bacteria,4P4V9@976|Bacteroidetes,47XV7@768503|Cytophagia	976|Bacteroidetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_47994_4	1197906.CAJQ02000027_gene1525	1.998e-07	56.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JV1X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TLS3_k127_47994_0	1237149.C900_04801	5.57e-136	443.0	COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,47KWG@768503|Cytophagia	976|Bacteroidetes	EJ	TIGRFAM L-asparaginases, type I	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
TLS3_k127_47994_1	313606.M23134_04517	3.989e-112	367.0	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,47KE3@768503|Cytophagia	976|Bacteroidetes	L	TIGRFAM hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
TLS3_k127_47994_3	742723.HMPREF9477_01034	1.954e-25	109.0	COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,248FD@186801|Clostridia,27NEX@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Prokaryotic diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar,PAP2
TLS3_k127_47994_2	946077.W5A_02095	5.376e-55	203.0	COG0707@1|root,COG0707@2|Bacteria,4NFRJ@976|Bacteroidetes,1HXSS@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
TLS3_k127_4824720_0	1237149.C900_00289	5.845e-179	586.0	COG3857@1|root,COG3857@2|Bacteria,4PKEH@976|Bacteroidetes,47YDH@768503|Cytophagia	976|Bacteroidetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Exonuc_V_gamma,PDDEXK_1
TLS3_k127_4837735_1	1121904.ARBP01000001_gene5718	4.506e-182	579.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,47N2A@768503|Cytophagia	976|Bacteroidetes	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
TLS3_k127_4837735_2	7176.CPIJ016457-PA	3.726e-05	47.0	2E6X1@1|root,2S9Y9@2759|Eukaryota,3AIF6@33154|Opisthokonta	7176.CPIJ016457-PA|-	S	Conserved hypothetical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4837735_0	643867.Ftrac_2237	3.69e-271	845.0	COG1228@1|root,COG1228@2|Bacteria,4NG0U@976|Bacteroidetes,47NDK@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
TLS3_k127_4848621_1	1185876.BN8_06543	1.727e-143	459.0	COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,47KHD@768503|Cytophagia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
TLS3_k127_4848621_0	1185876.BN8_06544	3.405e-283	889.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,4NF3R@976|Bacteroidetes,47N7W@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4,Peptidase_M1
TLS3_k127_484949_5	929556.Solca_2364	2.272e-15	77.0	COG1752@1|root,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,1IPVY@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
TLS3_k127_484949_3	1237149.C900_00751	1.128e-162	522.0	COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,47MV0@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_484949_1	1237149.C900_00753	3.245e-301	938.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,47JTC@768503|Cytophagia	976|Bacteroidetes	CO	Cytochrome c biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
TLS3_k127_484949_2	1237149.C900_00811	6.37e-183	580.0	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,47JBT@768503|Cytophagia	976|Bacteroidetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS3_k127_484949_4	1124780.ANNU01000005_gene2378	1.667e-95	319.0	COG0596@1|root,COG0596@2|Bacteria,4NDZI@976|Bacteroidetes,47JB4@768503|Cytophagia	976|Bacteroidetes	S	Serine aminopeptidase, S33	ybfF	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_484949_0	1237149.C900_04576	8.363e-313	965.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,47K0C@768503|Cytophagia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
TLS3_k127_4856717_1	1124780.ANNU01000008_gene2688	8.883e-107	352.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,47MCC@768503|Cytophagia	976|Bacteroidetes	K	lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
TLS3_k127_4856717_0	1124780.ANNU01000008_gene2689	7.281e-125	407.0	COG0246@1|root,COG0246@2|Bacteria,4NEMT@976|Bacteroidetes,47K47@768503|Cytophagia	976|Bacteroidetes	G	PFAM Mannitol dehydrogenase	uxaB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009026,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	1.1.1.17,1.1.1.58	ko:K00009,ko:K00041	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00631	R02555,R02703	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
TLS3_k127_4875204_6	1144313.PMI10_01976	2.218e-50	183.0	COG3250@1|root,COG3250@2|Bacteria,4NEDP@976|Bacteroidetes,1IMPI@117743|Flavobacteriia,2NUP4@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_2_N,SASA
TLS3_k127_4875204_7	1237149.C900_02751	6.507e-36	141.0	2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,47PP1@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated lipoprotein, GldH	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	GldH_lipo
TLS3_k127_4875204_1	1237149.C900_02750	2.854e-181	574.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,47M8P@768503|Cytophagia	976|Bacteroidetes	S	PFAM PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
TLS3_k127_4875204_2	1237149.C900_02749	1.263e-174	559.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,47JIA@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
TLS3_k127_4875204_0	1237149.C900_02748	0.0	1146.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,47JD8@768503|Cytophagia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
TLS3_k127_4875204_4	1237149.C900_02747	2.432e-142	458.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,4NED8@976|Bacteroidetes,47KGF@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
TLS3_k127_4875204_3	1237149.C900_02746	3.93e-147	473.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,47KJZ@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
TLS3_k127_4875204_5	1237149.C900_01775	2.111e-72	246.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47M5P@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
TLS3_k127_487612_0	1123037.AUDE01000052_gene2568	1.165e-259	816.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,1HX30@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
TLS3_k127_4879117_1	1047013.AQSP01000089_gene1181	8.118e-154	509.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	cyaJ	-	4.6.1.1	ko:K01768,ko:K02483	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	Guanylate_cyc,HTH_18,TPR_16,TPR_19,TPR_2,TPR_8
TLS3_k127_4879117_2	1166018.FAES_1942	7.682e-109	359.0	COG3970@1|root,COG3970@2|Bacteria,4NGTH@976|Bacteroidetes,47MQU@768503|Cytophagia	976|Bacteroidetes	S	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
TLS3_k127_4879117_0	926549.KI421517_gene1800	1.405e-169	546.0	COG1012@1|root,COG1012@2|Bacteria,4NEKG@976|Bacteroidetes,47MQT@768503|Cytophagia	976|Bacteroidetes	C	PFAM Aldehyde dehydrogenase	aldH	-	1.2.1.26	ko:K13877	ko00040,ko00053,map00040,map00053	-	R00264	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
TLS3_k127_48825_1	1123277.KB893195_gene5671	1.231e-252	799.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47MYR@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_48825_0	1237149.C900_01529	3.46e-260	827.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_48825_2	700598.Niako_1201	4.587e-05	46.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia	976|Bacteroidetes	V	TIGRFAM Acidobacterial duplicated orphan permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_4886201_2	471854.Dfer_1198	1.163e-45	170.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,47PEN@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
TLS3_k127_4886201_1	471854.Dfer_1197	9.25e-47	181.0	COG2207@1|root,COG2207@2|Bacteria,4NEEQ@976|Bacteroidetes,47RA1@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	pchR	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_4886201_0	1237149.C900_05504	6.796e-116	380.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,47JF5@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
TLS3_k127_4892948_6	714943.Mucpa_2551	1.401e-05	47.0	2EIUI@1|root,33CJV@2|Bacteria,4NYR6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4892948_2	1237149.C900_04527	4.634e-65	231.0	COG4235@1|root,COG4235@2|Bacteria,4PMDP@976|Bacteroidetes,47Y29@768503|Cytophagia	976|Bacteroidetes	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
TLS3_k127_4892948_4	1121373.KB903620_gene2207	4.829e-43	159.0	COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,47QBN@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the bacterial histone-like protein family	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
TLS3_k127_4892948_0	1237149.C900_04529	7.483e-115	380.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,47KTH@768503|Cytophagia	976|Bacteroidetes	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
TLS3_k127_4892948_3	1237149.C900_04530	1.813e-57	203.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,47QZT@768503|Cytophagia	976|Bacteroidetes	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
TLS3_k127_4892948_1	1237149.C900_04531	1.543e-108	365.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,47JUX@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated protein GldE	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
TLS3_k127_4892948_5	1237149.C900_04532	1.72e-34	135.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,47PUM@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated lipoprotein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4900474_1	1279009.ADICEAN_01459	1.317e-185	584.0	COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,47K6D@768503|Cytophagia	976|Bacteroidetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
TLS3_k127_4900474_0	1237149.C900_01138	8.245e-186	589.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,47J9P@768503|Cytophagia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_4900474_2	1279009.ADICEAN_03136	5.263e-179	565.0	COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,47J9B@768503|Cytophagia	976|Bacteroidetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
TLS3_k127_4900474_3	1237149.C900_01135	1.425e-28	117.0	COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,47P6K@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
TLS3_k127_4902832_8	1237149.C900_01231	2.046e-71	247.0	COG3417@1|root,COG3417@2|Bacteria,4NFXF@976|Bacteroidetes,47Q1R@768503|Cytophagia	976|Bacteroidetes	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
TLS3_k127_4902832_2	1237149.C900_01232	7.1e-164	528.0	COG3014@1|root,COG3014@2|Bacteria,4NIIU@976|Bacteroidetes,47K7B@768503|Cytophagia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	TPR_2
TLS3_k127_4902832_4	1237149.C900_01235	9.04e-99	333.0	2EG6T@1|root,339YP@2|Bacteria,4NXNK@976|Bacteroidetes,47T48@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4902832_0	1237149.C900_04189	0.0	1326.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,47K30@768503|Cytophagia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
TLS3_k127_4902832_7	1237149.C900_04190	2.809e-83	291.0	COG0457@1|root,COG0457@2|Bacteria,4NFHT@976|Bacteroidetes,47PQF@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
TLS3_k127_4902832_5	1237149.C900_00334	3.311e-91	306.0	COG1596@1|root,COG1596@2|Bacteria,4NFXJ@976|Bacteroidetes,47Q2A@768503|Cytophagia	976|Bacteroidetes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
TLS3_k127_4902832_1	1237149.C900_00335	2.699e-275	867.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia	976|Bacteroidetes	DM	TIGRFAM capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
TLS3_k127_4902832_3	1237149.C900_00339	1.936e-146	468.0	COG1216@1|root,COG1216@2|Bacteria,4NK0K@976|Bacteroidetes,47PID@768503|Cytophagia	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4906624_1	1239962.C943_03954	9.612e-28	115.0	2CDAN@1|root,309X8@2|Bacteria,4NRN2@976|Bacteroidetes,47QB3@768503|Cytophagia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
TLS3_k127_4906624_0	388413.ALPR1_06265	3.931e-282	874.0	COG2303@1|root,COG2303@2|Bacteria,4NK1Z@976|Bacteroidetes,47NME@768503|Cytophagia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
TLS3_k127_4909234_2	1202532.FF52_22464	6.599e-61	219.0	COG0642@1|root,COG2205@2|Bacteria,4P2BP@976|Bacteroidetes,1IKQ9@117743|Flavobacteriia,2P0TB@237|Flavobacterium	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_4909234_0	926562.Oweho_0070	6.362e-121	399.0	28I3N@1|root,2Z87C@2|Bacteria,4NE8P@976|Bacteroidetes,1HWQW@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
TLS3_k127_4909234_1	313606.M23134_03596	2.111e-69	239.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,47K59@768503|Cytophagia	976|Bacteroidetes	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
TLS3_k127_4912613_12	1123277.KB893172_gene852	1.847e-12	69.0	COG2169@1|root,COG2169@2|Bacteria,4PNWY@976|Bacteroidetes,47KQ8@768503|Cytophagia	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_4912613_10	1123277.KB893172_gene854	3.601e-39	151.0	COG5485@1|root,COG5485@2|Bacteria,4NRQT@976|Bacteroidetes,47QG9@768503|Cytophagia	976|Bacteroidetes	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
TLS3_k127_4912613_1	1237149.C900_04571	7.681e-172	546.0	COG0535@1|root,COG0535@2|Bacteria,4NFRX@976|Bacteroidetes,47KUF@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
TLS3_k127_4912613_8	1237149.C900_04570	4.575e-52	186.0	COG0599@1|root,COG0599@2|Bacteria,4NNPC@976|Bacteroidetes,47QDA@768503|Cytophagia	976|Bacteroidetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
TLS3_k127_4912613_2	1237149.C900_04921	8.699e-119	389.0	COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,47MKU@768503|Cytophagia	976|Bacteroidetes	M	Transglycosylase SLT domain	mltD_2	-	-	-	-	-	-	-	-	-	-	-	SLT
TLS3_k127_4912613_0	1237149.C900_01015	3.038e-302	951.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,47M4H@768503|Cytophagia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_4912613_5	1121373.KB903662_gene3	2.705e-81	274.0	COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes,47JKF@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
TLS3_k127_4912613_4	1239962.C943_03143	4.28e-93	308.0	COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,47M4J@768503|Cytophagia	976|Bacteroidetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
TLS3_k127_4912613_11	1123057.P872_06665	2.55e-15	79.0	2EK82@1|root,33DYE@2|Bacteria,4NYF0@976|Bacteroidetes,47SMK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
TLS3_k127_4912613_3	1189612.A33Q_0537	1.648e-98	324.0	COG1595@1|root,COG1595@2|Bacteria,4NEFR@976|Bacteroidetes,47JFG@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_4912613_9	1120968.AUBX01000013_gene3489	2.502e-40	159.0	COG0438@1|root,COG0438@2|Bacteria,4NWCX@976|Bacteroidetes,47YNM@768503|Cytophagia	976|Bacteroidetes	M	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
TLS3_k127_4912613_7	760192.Halhy_2467	2.45e-70	247.0	COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,1ISZE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
TLS3_k127_4912613_6	1237149.C900_01007	9.36e-79	266.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,47KQ9@768503|Cytophagia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
TLS3_k127_4924666_0	1453505.JASY01000001_gene3230	1.034e-179	575.0	COG3039@1|root,COG3039@2|Bacteria,4PKH0@976|Bacteroidetes,1HXKB@117743|Flavobacteriia,2NZZJ@237|Flavobacterium	976|Bacteroidetes	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
TLS3_k127_4924666_1	382464.ABSI01000017_gene45	4.168e-10	60.0	COG0673@1|root,COG0673@2|Bacteria,46SBW@74201|Verrucomicrobia,2ITSJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_4926928_2	1185876.BN8_02585	8.113e-161	511.0	COG0642@1|root,COG2205@2|Bacteria,4NEZM@976|Bacteroidetes,47JJ4@768503|Cytophagia	976|Bacteroidetes	T	Osmosensitive K+ channel His kinase sensor domain	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	KdpD,Usp
TLS3_k127_4926928_3	762903.Pedsa_1587	2.411e-155	498.0	2CB8G@1|root,2Z88H@2|Bacteria,4NF68@976|Bacteroidetes,1IR13@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
TLS3_k127_4926928_4	1123277.KB893202_gene6233	3.024e-63	222.0	COG2156@1|root,COG2156@2|Bacteria,4NMME@976|Bacteroidetes,47MSV@768503|Cytophagia	976|Bacteroidetes	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
TLS3_k127_4926928_0	1454007.JAUG01000066_gene4648	0.0	1024.0	COG2216@1|root,COG2216@2|Bacteria,4NFBI@976|Bacteroidetes,1IP79@117747|Sphingobacteriia	976|Bacteroidetes	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
TLS3_k127_4926928_1	1288963.ADIS_1282	2.197e-243	763.0	COG2060@1|root,COG2060@2|Bacteria,4NF2G@976|Bacteroidetes,47NWP@768503|Cytophagia	976|Bacteroidetes	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
TLS3_k127_4926928_5	1121286.AUMT01000022_gene1708	4.061e-22	97.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWWK@117743|Flavobacteriia,3ZNH4@59732|Chryseobacterium	976|Bacteroidetes	T	Chemotaxis protein CheY	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_4929070_0	1237149.C900_03423	1.306e-308	975.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,47JS4@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
TLS3_k127_4929070_4	1237149.C900_03424	1.034e-126	413.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,47M1Q@768503|Cytophagia	976|Bacteroidetes	L	TIGRFAM DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
TLS3_k127_4929070_6	1237149.C900_03426	4.63e-58	207.0	COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,47R0S@768503|Cytophagia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TLS3_k127_4929070_2	1237149.C900_03428	1.134e-218	685.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47NKU@768503|Cytophagia	976|Bacteroidetes	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
TLS3_k127_4929070_3	1237149.C900_03429	9.504e-216	687.0	COG0642@1|root,COG0642@2|Bacteria,4NJVF@976|Bacteroidetes,47Y2W@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Reg_prop,Response_reg
TLS3_k127_4929070_1	1237149.C900_03432	4.235e-242	815.0	COG3291@1|root,COG3291@2|Bacteria,4NJU9@976|Bacteroidetes,47NEJ@768503|Cytophagia	976|Bacteroidetes	Q	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,PKD
TLS3_k127_4929070_5	1121899.Q764_13760	5.044e-84	319.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,4NDZQ@976|Bacteroidetes,1IKR6@117743|Flavobacteriia,2P0US@237|Flavobacterium	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SprB
TLS3_k127_4929662_1	991.IW20_21765	1.183e-76	263.0	2BB2W@1|root,324J1@2|Bacteria,4NQTD@976|Bacteroidetes,1I3SW@117743|Flavobacteriia,2NVZD@237|Flavobacterium	976|Bacteroidetes	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
TLS3_k127_4929662_5	1392489.JPOL01000002_gene2656	6.669e-19	91.0	COG3550@1|root,COG3550@2|Bacteria,4NFYY@976|Bacteroidetes,1HXAI@117743|Flavobacteriia,2XJUT@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
TLS3_k127_4929662_4	926562.Oweho_1072	7.076e-46	168.0	COG2824@1|root,COG2824@2|Bacteria,4NEFZ@976|Bacteroidetes,1I37M@117743|Flavobacteriia	976|Bacteroidetes	P	Phosphonoacetate hydrolase	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
TLS3_k127_4929662_3	313606.M23134_06214	8.083e-61	222.0	COG2207@1|root,COG2207@2|Bacteria,4NF8Q@976|Bacteroidetes,47RSI@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_4929662_2	929562.Emtol_3357	2.751e-68	235.0	COG2080@1|root,COG2080@2|Bacteria,4NMVV@976|Bacteroidetes,47Q3P@768503|Cytophagia	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
TLS3_k127_4929662_0	471854.Dfer_0019	6.639e-251	787.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47N2K@768503|Cytophagia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
TLS3_k127_4935328_1	994573.T472_0204825	1.992e-08	63.0	2DBTP@1|root,2ZAZW@2|Bacteria,1V0GC@1239|Firmicutes,24IW0@186801|Clostridia	186801|Clostridia	S	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase
TLS3_k127_4935328_0	700598.Niako_3170	1.586e-154	517.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia	976|Bacteroidetes	V	TIGRFAM Acidobacterial duplicated orphan permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_4941452_0	1237149.C900_01769	5e-324	1002.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,47KFY@768503|Cytophagia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
TLS3_k127_4941452_2	929703.KE386491_gene510	4.052e-34	134.0	COG3118@1|root,COG3118@2|Bacteria,4NSE6@976|Bacteroidetes,47R3Q@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM bacillithiol system protein YtxJ	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
TLS3_k127_4941452_3	1237149.C900_01773	8.436e-15	77.0	28MPU@1|root,2ZAYW@2|Bacteria,4NRQD@976|Bacteroidetes,47NJK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_494379_2	655815.ZPR_2082	4.907e-10	74.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWPC@117743|Flavobacteriia	976|Bacteroidetes	M	Cell envelope biogenesis protein AsmA	-	-	-	-	-	-	-	-	-	-	-	-	TamB
TLS3_k127_494379_0	1123277.KB893203_gene6259	9.991e-117	385.0	COG0624@1|root,COG0624@2|Bacteria,4NJEK@976|Bacteroidetes,47N41@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M20/M25/M40	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
TLS3_k127_494379_1	1210884.HG799464_gene10506	3.579e-22	96.0	COG1118@1|root,COG1118@2|Bacteria,2J54I@203682|Planctomycetes	203682|Planctomycetes	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_3
TLS3_k127_496952_2	643867.Ftrac_2046	2.01e-86	291.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,47MH4@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
TLS3_k127_496952_1	1111479.AXAR01000002_gene1933	9.022e-133	433.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,277WW@186823|Alicyclobacillaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_496952_0	1237149.C900_00890	1.186e-193	609.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,47JG0@768503|Cytophagia	976|Bacteroidetes	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
TLS3_k127_496952_3	1237149.C900_04552	8.051e-67	232.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,47PEY@768503|Cytophagia	976|Bacteroidetes	J	PFAM SpoU rRNA Methylase family	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
TLS3_k127_4978254_1	1123248.KB893348_gene225	1.382e-50	184.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1IRJZ@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_9,Reg_prop,Response_reg,Y_Y_Y
TLS3_k127_4978254_2	1189620.AJXL01000008_gene2290	1.792e-30	124.0	COG0745@1|root,COG0745@2|Bacteria,4NQNT@976|Bacteroidetes,1I3AQ@117743|Flavobacteriia,2P0IK@237|Flavobacterium	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_4978254_3	468059.AUHA01000003_gene1445	6.032e-19	99.0	COG1413@1|root,COG1413@2|Bacteria,4NN7Q@976|Bacteroidetes,1IXRV@117747|Sphingobacteriia	976|Bacteroidetes	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
TLS3_k127_4978254_0	468059.AUHA01000003_gene1446	1.978e-176	565.0	COG1215@1|root,COG1215@2|Bacteria,4NH18@976|Bacteroidetes,1IWIJ@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,Sulfatase
TLS3_k127_4980246_1	1237149.C900_02864	4.242e-34	134.0	28ICP@1|root,2Z8EZ@2|Bacteria,4NKKI@976|Bacteroidetes,47N2N@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4980246_0	1237149.C900_02863	1.4e-157	507.0	COG0457@1|root,COG0457@2|Bacteria,4PM6F@976|Bacteroidetes,47Y4H@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
TLS3_k127_4980246_2	1237149.C900_02862	9.749e-14	74.0	2C6AJ@1|root,304IU@2|Bacteria,4NPQW@976|Bacteroidetes,47Q1B@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_498883_0	700598.Niako_1610	2.61e-205	648.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1IRBM@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_498883_2	643867.Ftrac_0548	8.791e-76	264.0	COG2267@1|root,COG2267@2|Bacteria,4NPD2@976|Bacteroidetes,47XYA@768503|Cytophagia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_498883_1	1168289.AJKI01000035_gene3574	2.36e-181	575.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,2FM2Z@200643|Bacteroidia,3XJH4@558415|Marinilabiliaceae	976|Bacteroidetes	F	CobB/CobQ-like glutamine amidotransferase domain	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
TLS3_k127_4990817_4	1166018.FAES_0507	4.857e-08	57.0	28Q1T@1|root,2ZCK1@2|Bacteria,4NN1T@976|Bacteroidetes,47PK9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4990817_2	485918.Cpin_1976	2.024e-49	183.0	COG1131@1|root,COG1131@2|Bacteria,4NNVS@976|Bacteroidetes,1IS4J@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_4990817_0	1122621.ATZA01000024_gene2184	4.777e-58	207.0	COG0503@1|root,COG0503@2|Bacteria,4NP7K@976|Bacteroidetes,1IS3F@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
TLS3_k127_4990817_1	1237149.C900_04409	5.754e-50	187.0	COG2802@1|root,COG2802@2|Bacteria,4NEJU@976|Bacteroidetes	976|Bacteroidetes	S	Peptidase S16, lon domain protein	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
TLS3_k127_4999052_5	1122226.AUHX01000006_gene2155	2.502e-19	88.0	COG3250@1|root,COG3250@2|Bacteria,4NE9C@976|Bacteroidetes,1HYIU@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
TLS3_k127_4999052_4	1453498.LG45_01315	9.591e-29	118.0	2BK4N@1|root,32EI9@2|Bacteria,4PAAP@976|Bacteroidetes,1ID8A@117743|Flavobacteriia,2NXPD@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4999052_1	864565.HMPREF0379_1619	7.598e-58	219.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia	186801|Clostridia	KLT	PFAM KWG Leptospira repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
TLS3_k127_4999052_3	1122621.ATZA01000058_gene4132	2.336e-43	163.0	2EDZD@1|root,337U4@2|Bacteria,4PNWM@976|Bacteroidetes,1IU9Y@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4999052_0	929556.Solca_3760	6.846e-85	295.0	2BZ4W@1|root,2Z7PQ@2|Bacteria,4NJ1R@976|Bacteroidetes,1IXXV@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4999052_2	1202532.FF52_10323	9.194e-48	176.0	2DMAS@1|root,32DYG@2|Bacteria,4NRFT@976|Bacteroidetes,1I8RY@117743|Flavobacteriia,2NXBC@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5013727_1	761193.Runsl_3623	3.019e-19	97.0	2E25C@1|root,32XC8@2|Bacteria,4NTJ4@976|Bacteroidetes,47QKP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5018215_0	1250006.JHZZ01000001_gene1230	1.675e-161	520.0	COG0578@1|root,COG0578@2|Bacteria,4PKIZ@976|Bacteroidetes,1IJMF@117743|Flavobacteriia,3VW3V@52959|Polaribacter	976|Bacteroidetes	C	C-terminal domain of alpha-glycerophosphate oxidase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
TLS3_k127_5018215_1	700598.Niako_6353	2.235e-118	388.0	COG1940@1|root,COG1940@2|Bacteria,4NGC1@976|Bacteroidetes,1IURS@117747|Sphingobacteriia	976|Bacteroidetes	GK	COGs COG1940 Transcriptional regulator sugar kinase	-	-	-	-	-	-	-	-	-	-	-	-	ROK
TLS3_k127_5018215_2	1121875.KB907546_gene2534	2.841e-39	149.0	COG0524@1|root,COG0524@2|Bacteria,4NJIK@976|Bacteroidetes,1I00V@117743|Flavobacteriia	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
TLS3_k127_5020557_1	317936.Nos7107_1340	1.198e-63	227.0	COG0438@1|root,COG4641@1|root,COG0438@2|Bacteria,COG4641@2|Bacteria,1FZUY@1117|Cyanobacteria,1HM22@1161|Nostocales	1117|Cyanobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_21,Methyltransf_23,Methyltransf_24
TLS3_k127_5020557_0	421072.IO89_02770	2.857e-115	385.0	COG1134@1|root,COG1134@2|Bacteria,4NEDM@976|Bacteroidetes,1HXJV@117743|Flavobacteriia,3HIAG@358033|Chryseobacterium	976|Bacteroidetes	GM	ATPases associated with a variety of cellular activities	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
TLS3_k127_5020684_0	1317122.ATO12_23895	3.551e-126	414.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1HX0V@117743|Flavobacteriia,2YH52@290174|Aquimarina	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_5020684_1	1121904.ARBP01000013_gene425	4.365e-39	147.0	COG1695@1|root,COG1695@2|Bacteria,4NTYF@976|Bacteroidetes,47R1G@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_5037852_1	1121957.ATVL01000011_gene3911	9.19e-47	174.0	COG0664@1|root,COG0664@2|Bacteria,4NNIX@976|Bacteroidetes,47QT6@768503|Cytophagia	976|Bacteroidetes	T	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
TLS3_k127_5037852_0	1237149.C900_04485	6.979e-134	429.0	COG2013@1|root,COG2013@2|Bacteria,4NFNA@976|Bacteroidetes,47KS9@768503|Cytophagia	976|Bacteroidetes	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
TLS3_k127_5037852_2	1237149.C900_04484	3.342e-15	76.0	2E4W4@1|root,32ZQB@2|Bacteria,4NUZZ@976|Bacteroidetes,47RZI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5041073_1	926556.Echvi_1419	2.181e-50	181.0	COG0346@1|root,COG0346@2|Bacteria,4NSVP@976|Bacteroidetes	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_5041073_0	1123057.P872_09325	2.735e-300	927.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TLS3_k127_5041073_2	641524.ADICYQ_2111	1.637e-09	60.0	2ATIR@1|root,31J2R@2|Bacteria,4NR1Z@976|Bacteroidetes,47QYN@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
TLS3_k127_5043651_1	880071.Fleli_1281	1.397e-122	398.0	COG2220@1|root,COG2220@2|Bacteria,4NENZ@976|Bacteroidetes,47JT5@768503|Cytophagia	976|Bacteroidetes	S	COGs COG2220 Zn-dependent hydrolase of the beta-lactamase fold	romA	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
TLS3_k127_5043651_2	1121904.ARBP01000004_gene1098	1.942e-87	294.0	COG1028@1|root,COG1028@2|Bacteria,4NFXD@976|Bacteroidetes,47K99@768503|Cytophagia	976|Bacteroidetes	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_5043651_0	694427.Palpr_0308	2.34e-143	461.0	COG0702@1|root,COG0702@2|Bacteria,4NEJF@976|Bacteroidetes,2FN9A@200643|Bacteroidia,22ZFW@171551|Porphyromonadaceae	976|Bacteroidetes	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,Epimerase,NAD_binding_10
TLS3_k127_5044073_1	1239962.C943_02746	9.125e-82	275.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,47JG6@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
TLS3_k127_5044073_5	1349822.NSB1T_09495	1.135e-13	79.0	COG3047@1|root,COG3047@2|Bacteria,4NP9X@976|Bacteroidetes,2FMHB@200643|Bacteroidia,22XWW@171551|Porphyromonadaceae	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_5044073_4	1235803.C825_00138	1.963e-22	106.0	28N4A@1|root,2ZB9T@2|Bacteria,4NS50@976|Bacteroidetes,2G36J@200643|Bacteroidia,23208@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
TLS3_k127_5044073_0	1237149.C900_00280	4.866e-109	360.0	COG1575@1|root,COG1575@2|Bacteria,4NGCJ@976|Bacteroidetes,47JDA@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
TLS3_k127_5044073_3	1121904.ARBP01000002_gene7012	1.936e-32	132.0	COG0782@1|root,COG0782@2|Bacteria,4NQAD@976|Bacteroidetes,47QDF@768503|Cytophagia	976|Bacteroidetes	K	Transcription elongation factor	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB
TLS3_k127_5044073_2	1124780.ANNU01000024_gene3056	1.126e-65	229.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,47P7U@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	gpx1	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
TLS3_k127_5044073_6	643867.Ftrac_3240	5.891e-11	63.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,47P7U@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	gpx1	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
TLS3_k127_5058968_1	504472.Slin_6131	2.307e-243	768.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,47MWY@768503|Cytophagia	976|Bacteroidetes	EU	Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
TLS3_k127_5058968_0	1237149.C900_03253	0.0	1040.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,47JCZ@768503|Cytophagia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
TLS3_k127_5058968_2	761193.Runsl_1646	2.68e-169	535.0	COG0667@1|root,COG0667@2|Bacteria,4NHA1@976|Bacteroidetes,47NMZ@768503|Cytophagia	976|Bacteroidetes	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_5058968_3	1237149.C900_03252	1.01e-115	376.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,47JQE@768503|Cytophagia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
TLS3_k127_5072654_0	1121904.ARBP01000004_gene1091	2.043e-210	682.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_5072654_1	929562.Emtol_1291	8.27e-175	555.0	2DB8U@1|root,2Z7SW@2|Bacteria,4NEUK@976|Bacteroidetes,47NX9@768503|Cytophagia	976|Bacteroidetes	S	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase
TLS3_k127_5072654_2	143224.JQMD01000002_gene881	1.175e-124	405.0	COG1082@1|root,COG1082@2|Bacteria,4NJZQ@976|Bacteroidetes,1IIM2@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_5073273_1	1237149.C900_03938	6.271e-94	333.0	COG1729@1|root,COG1729@2|Bacteria,4PP99@976|Bacteroidetes,47VYS@768503|Cytophagia	976|Bacteroidetes	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
TLS3_k127_5073273_0	1237149.C900_02383	1.681e-216	681.0	28KRY@1|root,2ZA9E@2|Bacteria,4NI1H@976|Bacteroidetes,47N4R@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5073273_2	1237149.C900_02382	1.99e-58	205.0	COG0784@1|root,COG0784@2|Bacteria,4NRC9@976|Bacteroidetes,47QC7@768503|Cytophagia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_5073273_3	929556.Solca_4225	6.028e-15	74.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1INP0@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_5081467_0	700598.Niako_0780	2.65e-282	880.0	COG0841@1|root,COG0841@2|Bacteria,4NG7I@976|Bacteroidetes,1INVR@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS3_k127_5081467_1	700598.Niako_0781	1.733e-131	429.0	COG0845@1|root,COG0845@2|Bacteria,4NH4Z@976|Bacteroidetes,1INZ6@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
TLS3_k127_5081467_2	742727.HMPREF9447_00865	1.853e-78	266.0	COG2148@1|root,COG2148@2|Bacteria,4NF29@976|Bacteroidetes,2FNGF@200643|Bacteroidia,4ANCY@815|Bacteroidaceae	976|Bacteroidetes	M	Psort location CytoplasmicMembrane, score	pglC	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
TLS3_k127_5081467_3	1121481.AUAS01000014_gene2467	1.577e-38	150.0	COG0110@1|root,COG0110@2|Bacteria,4NNTF@976|Bacteroidetes,47PVW@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family	-	-	-	ko:K19429	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,NAD_binding_9
TLS3_k127_5082339_0	1121904.ARBP01000060_gene1915	1.879e-206	652.0	COG0399@1|root,COG0399@2|Bacteria,4NE4B@976|Bacteroidetes,47M1Z@768503|Cytophagia	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_5082339_3	1340493.JNIF01000004_gene114	1.327e-39	161.0	COG0673@1|root,COG0673@2|Bacteria,3Y6XR@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_5082339_1	1121904.ARBP01000013_gene303	1.647e-130	428.0	28KPG@1|root,2ZA7K@2|Bacteria,4NFWJ@976|Bacteroidetes,47MDA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5082339_2	1121904.ARBP01000018_gene2704	6.425e-103	339.0	COG4409@1|root,COG4409@2|Bacteria,4NIJX@976|Bacteroidetes,47MH2@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TLS3_k127_5109054_4	1237149.C900_01452	1.255e-32	133.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C,CHU_C,DUF11,DUF5011,Gram_pos_anchor,Laminin_G_3,SdrD_B
TLS3_k127_5109054_1	1048983.EL17_10290	3.488e-105	351.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,47K6Q@768503|Cytophagia	976|Bacteroidetes	C	PFAM Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
TLS3_k127_5109054_2	1279009.ADICEAN_01172	3.333e-64	221.0	COG0437@1|root,COG0437@2|Bacteria,4PKQE@976|Bacteroidetes,47XYY@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S binding domain	fdx	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,Fer4_8
TLS3_k127_5109054_0	1237149.C900_05083	2.063e-117	384.0	COG1721@1|root,COG1721@2|Bacteria,4NG0C@976|Bacteroidetes,47JTH@768503|Cytophagia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TLS3_k127_5109054_3	1237149.C900_05084	1.516e-46	170.0	2ASD9@1|root,31HSR@2|Bacteria,4NQ71@976|Bacteroidetes,47R7K@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3276)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3276
TLS3_k127_5119218_0	1089547.KB913013_gene4651	0.0	1032.0	COG2010@1|root,COG2010@2|Bacteria,4NEPV@976|Bacteroidetes,47P04@768503|Cytophagia	976|Bacteroidetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
TLS3_k127_5119218_3	1237149.C900_03617	2.073e-66	231.0	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,47QN0@768503|Cytophagia	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
TLS3_k127_5119218_1	1237149.C900_03616	6.913e-73	248.0	COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,47PV8@768503|Cytophagia	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
TLS3_k127_5119218_2	1237149.C900_03615	7.062e-73	252.0	arCOG05416@1|root,2ZZTD@2|Bacteria,4NNMY@976|Bacteroidetes,47Q57@768503|Cytophagia	976|Bacteroidetes	S	lycopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5119218_4	1237149.C900_05294	1.349e-29	119.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_513577_1	1123248.KB893321_gene473	7.181e-46	167.0	COG4198@1|root,COG4198@2|Bacteria,4NI11@976|Bacteroidetes,1IQ9Y@117747|Sphingobacteriia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like
TLS3_k127_513577_0	471854.Dfer_4979	3.709e-225	717.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47KJ4@768503|Cytophagia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
TLS3_k127_515467_6	643867.Ftrac_1269	1.608e-18	91.0	COG0642@1|root,COG2205@2|Bacteria,4NX2D@976|Bacteroidetes,47T5N@768503|Cytophagia	976|Bacteroidetes	T	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
TLS3_k127_515467_2	1237149.C900_01070	3.414e-95	323.0	COG0248@1|root,COG0248@2|Bacteria,4NH03@976|Bacteroidetes,47K3H@768503|Cytophagia	976|Bacteroidetes	FP	Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
TLS3_k127_515467_0	1237149.C900_01071	3.868e-285	883.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,47K3E@768503|Cytophagia	976|Bacteroidetes	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
TLS3_k127_515467_1	1237149.C900_01074	5.969e-183	576.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,47MIG@768503|Cytophagia	976|Bacteroidetes	G	PFAM M42 glutamyl aminopeptidase	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
TLS3_k127_515467_3	1237149.C900_01077	3.001e-55	200.0	COG0642@1|root,COG2205@2|Bacteria,4NX2D@976|Bacteroidetes,47T5N@768503|Cytophagia	976|Bacteroidetes	T	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
TLS3_k127_515467_4	1237149.C900_01077	7.114e-52	188.0	COG0642@1|root,COG2205@2|Bacteria,4NX2D@976|Bacteroidetes,47T5N@768503|Cytophagia	976|Bacteroidetes	T	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
TLS3_k127_515467_5	153721.MYP_107	4.045e-26	115.0	COG4251@1|root,COG5002@1|root,COG4251@2|Bacteria,COG5002@2|Bacteria,4PKM7@976|Bacteroidetes,47XWE@768503|Cytophagia	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9
TLS3_k127_5158441_5	1267211.KI669560_gene354	1.072e-05	49.0	COG2963@1|root,COG2963@2|Bacteria,4NZDV@976|Bacteroidetes	976|Bacteroidetes	L	PFAM transposase IS3 IS911 family protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
TLS3_k127_5158441_2	760192.Halhy_5193	6.293e-13	76.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911,DUF4440,SnoaL_3
TLS3_k127_5158441_1	1121904.ARBP01000027_gene759	0.0	1118.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47KMJ@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_5158441_0	760192.Halhy_0960	0.0	1125.0	COG4447@1|root,COG4447@2|Bacteria,4P16I@976|Bacteroidetes,1IWTV@117747|Sphingobacteriia	2|Bacteria	G	SPTR Glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
TLS3_k127_5158441_4	411479.BACUNI_03518	3.42e-06	54.0	COG4219@1|root,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,2FNCU@200643|Bacteroidia,4ANSE@815|Bacteroidaceae	976|Bacteroidetes	KT	COG NOG25147 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
TLS3_k127_5158441_3	313628.LNTAR_17623	3.616e-07	55.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TLS3_k127_5166261_0	1237149.C900_00709	9.612e-171	540.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,47JT9@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_5166261_1	1237149.C900_00710	1.264e-89	299.0	COG3000@1|root,COG3000@2|Bacteria,4NMV7@976|Bacteroidetes,47PA0@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
TLS3_k127_5166261_2	866536.Belba_1482	2.204e-48	176.0	COG4867@1|root,COG4867@2|Bacteria,4NFMA@976|Bacteroidetes,47K13@768503|Cytophagia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
TLS3_k127_517206_1	1519464.HY22_12800	3.973e-14	78.0	COG3667@1|root,COG3667@2|Bacteria	2|Bacteria	P	copper resistance	copB	-	-	ko:K07233,ko:K07798,ko:K14588	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CopB,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,CusF_Ec,HlyD_D23
TLS3_k127_517206_0	1237149.C900_00062	7.97e-242	761.0	COG1131@1|root,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,47KQD@768503|Cytophagia	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,TerB
TLS3_k127_5178799_2	742727.HMPREF9447_02043	2.197e-05	50.0	COG3637@1|root,COG3637@2|Bacteria,4NRZA@976|Bacteroidetes,2FMYY@200643|Bacteroidia,4AQ7T@815|Bacteroidaceae	976|Bacteroidetes	M	COG NOG19089 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
TLS3_k127_5178799_0	616991.JPOO01000001_gene3807	1.329e-133	445.0	COG0457@1|root,COG0457@2|Bacteria,4NH87@976|Bacteroidetes,1HZMD@117743|Flavobacteriia,23FU8@178469|Arenibacter	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
TLS3_k127_5178799_1	643867.Ftrac_1484	4.078e-44	163.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,47KYQ@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
TLS3_k127_5205108_0	1237149.C900_04535	2.505e-278	867.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,47JUE@768503|Cytophagia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
TLS3_k127_5205108_2	1237149.C900_03190	5.289e-54	192.0	COG0346@1|root,COG0346@2|Bacteria,4NRSZ@976|Bacteroidetes,47QSC@768503|Cytophagia	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_5205108_1	1237149.C900_03189	7.721e-104	342.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,47MJV@768503|Cytophagia	976|Bacteroidetes	S	Nitronate monooxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
TLS3_k127_5209359_0	1237149.C900_04024	2.5e-77	266.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,47MWE@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
TLS3_k127_5209359_2	1237149.C900_04025	5.189e-65	229.0	2AEI8@1|root,331SH@2|Bacteria,4NWWM@976|Bacteroidetes,47S6K@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5209359_1	1237149.C900_04026	3.5e-75	258.0	COG1452@1|root,COG1452@2|Bacteria,4NDU3@976|Bacteroidetes,47KAE@768503|Cytophagia	976|Bacteroidetes	M	OstA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OstA,OstA_2
TLS3_k127_5230478_3	1121481.AUAS01000012_gene342	1.395e-27	113.0	COG1409@1|root,COG4775@1|root,COG1409@2|Bacteria,COG4775@2|Bacteria,4NF9N@976|Bacteroidetes,47JAP@768503|Cytophagia	976|Bacteroidetes	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Metallophos,ShlB
TLS3_k127_5230478_1	714943.Mucpa_3116	6.749e-54	197.0	COG0586@1|root,COG0586@2|Bacteria,4NMBP@976|Bacteroidetes,1IRXI@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
TLS3_k127_5230478_0	1550091.JROE01000002_gene1138	1.431e-293	920.0	COG1629@1|root,COG4771@2|Bacteria,4PKE0@976|Bacteroidetes,1IRNN@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_5230478_4	1392498.JQLH01000001_gene3748	8.97e-24	105.0	COG2197@1|root,COG2197@2|Bacteria,4PKIY@976|Bacteroidetes,1IJAH@117743|Flavobacteriia,2PIQB@252356|Maribacter	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_5230478_2	1237149.C900_02651	4.012e-53	190.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47X9U@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
TLS3_k127_5234231_0	1279009.ADICEAN_01012	6.866e-170	541.0	28JQV@1|root,2Z7R2@2|Bacteria,4NJF2@976|Bacteroidetes,47KDX@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5234231_1	926562.Oweho_1605	2.787e-78	278.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,1HWUK@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_3,PAS_4,PAS_9
TLS3_k127_5234998_5	929562.Emtol_1132	4.719e-85	287.0	COG4977@1|root,COG4977@2|Bacteria,4NHHE@976|Bacteroidetes,47N5H@768503|Cytophagia	976|Bacteroidetes	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
TLS3_k127_5234998_8	929703.KE386491_gene195	4.719e-45	167.0	COG0346@1|root,COG0346@2|Bacteria,4NT9B@976|Bacteroidetes	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
TLS3_k127_5234998_3	1123057.P872_16955	9.406e-131	423.0	COG1621@1|root,COG1621@2|Bacteria,4PMRT@976|Bacteroidetes,47KJM@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_32N,Glyco_hydro_43
TLS3_k127_5234998_6	1279009.ADICEAN_04058	1.845e-75	263.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,47K8M@768503|Cytophagia	976|Bacteroidetes	O	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	fklB	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
TLS3_k127_5234998_1	1288963.ADIS_1302	9.62e-212	666.0	COG4225@1|root,COG4225@2|Bacteria,4NJYK@976|Bacteroidetes,47MFS@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
TLS3_k127_5234998_0	1120965.AUBV01000003_gene400	1.706e-222	699.0	COG1902@1|root,COG1902@2|Bacteria,4NG0N@976|Bacteroidetes,47JNR@768503|Cytophagia	976|Bacteroidetes	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
TLS3_k127_5234998_4	1121904.ARBP01000011_gene1474	5.638e-99	329.0	COG1028@1|root,COG1028@2|Bacteria,4NHVK@976|Bacteroidetes,47K2F@768503|Cytophagia	976|Bacteroidetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_5234998_2	1123248.KB893359_gene2089	1.656e-156	503.0	COG2133@1|root,COG2133@2|Bacteria,4PIUD@976|Bacteroidetes,1IXS9@117747|Sphingobacteriia	976|Bacteroidetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS3_k127_523586_0	1237149.C900_02826	0.0	1376.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,47JXI@768503|Cytophagia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase, E1	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
TLS3_k127_523586_2	1124780.ANNU01000052_gene3584	6.497e-203	643.0	COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,47K2Z@768503|Cytophagia	976|Bacteroidetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS3_k127_523586_1	1237149.C900_02822	1.481e-246	768.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,47K0E@768503|Cytophagia	976|Bacteroidetes	C	Dihydrolipoyl dehydrogenase	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_523586_3	643867.Ftrac_0465	0.0003058	49.0	COG0642@1|root,COG2205@2|Bacteria,4P2BP@976|Bacteroidetes	976|Bacteroidetes	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_5240932_2	743722.Sph21_4462	1.05e-81	275.0	COG4430@1|root,COG4430@2|Bacteria,4NN4Z@976|Bacteroidetes,1IRTA@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
TLS3_k127_5240932_0	700598.Niako_2371	0.0	1071.0	COG3669@1|root,COG3669@2|Bacteria,4NEDX@976|Bacteroidetes,1IQ6C@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM coagulation factor 5 8 type	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc
TLS3_k127_5240932_1	1144313.PMI10_00030	5.347e-126	412.0	COG5297@1|root,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Beta-lactamase,CBM60,CBM_2,Cellulase,DUF1593,PSCyt3,fn3
TLS3_k127_5241747_0	926549.KI421517_gene4109	2.87e-240	749.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47KVI@768503|Cytophagia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
TLS3_k127_5241747_5	926549.KI421517_gene4108	4.462e-81	271.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,47PGG@768503|Cytophagia	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
TLS3_k127_5241747_3	1121904.ARBP01000002_gene6934	2.352e-120	396.0	COG0263@1|root,COG0263@2|Bacteria,4NH75@976|Bacteroidetes,47KIA@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
TLS3_k127_5241747_1	926549.KI421517_gene1209	2.753e-167	535.0	COG0014@1|root,COG0014@2|Bacteria,4NEPQ@976|Bacteroidetes,47J99@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_5241747_4	688270.Celal_3016	1.491e-82	282.0	COG0627@1|root,COG0627@2|Bacteria,4NGI8@976|Bacteroidetes,1IIIN@117743|Flavobacteriia,1F9Q8@104264|Cellulophaga	976|Bacteroidetes	S	Putative esterase	xynC	-	-	-	-	-	-	-	-	-	-	-	Esterase
TLS3_k127_5241747_2	1121011.AUCB01000014_gene356	3.402e-148	477.0	COG1062@1|root,COG1062@2|Bacteria,4NF83@976|Bacteroidetes,1HY5N@117743|Flavobacteriia	976|Bacteroidetes	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_5251747_0	926562.Oweho_2942	9.677e-203	651.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,1HYJ3@117743|Flavobacteriia,2PAHE@246874|Cryomorphaceae	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
TLS3_k127_5286016_1	926549.KI421517_gene714	6.006e-124	407.0	COG0584@1|root,COG0584@2|Bacteria,4NMGN@976|Bacteroidetes,47NRY@768503|Cytophagia	976|Bacteroidetes	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
TLS3_k127_5286016_2	760192.Halhy_2187	2.362e-31	126.0	COG1695@1|root,COG1695@2|Bacteria,4PK5I@976|Bacteroidetes,1IZJS@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Transcriptional regulator PadR N-terminal-like	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_5286016_0	1123277.KB893195_gene5671	9.234e-130	428.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47MYR@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_529674_5	1237149.C900_05167	1.699e-45	170.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,47N7G@768503|Cytophagia	976|Bacteroidetes	O	Gliding motility protein, GldB	gldB	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_529674_7	1189612.A33Q_2676	8.035e-20	95.0	2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,47RV6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_529674_4	1237149.C900_00926	6.012e-79	267.0	COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,47MSF@768503|Cytophagia	976|Bacteroidetes	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
TLS3_k127_529674_0	1237149.C900_00927	0.0	1038.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,47KCK@768503|Cytophagia	976|Bacteroidetes	E	Aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
TLS3_k127_529674_1	1237149.C900_00928	0.0	1020.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,47KCK@768503|Cytophagia	976|Bacteroidetes	E	Aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
TLS3_k127_529674_2	929562.Emtol_3627	2.94e-123	402.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,47KNZ@768503|Cytophagia	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_529674_3	1237149.C900_01531	6.993e-93	313.0	COG2849@1|root,COG2849@2|Bacteria,4NK1X@976|Bacteroidetes,47NFY@768503|Cytophagia	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_529674_6	1237149.C900_03488	2.227e-25	106.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,47JAZ@768503|Cytophagia	976|Bacteroidetes	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
TLS3_k127_5298818_2	1237149.C900_01135	1.117e-51	185.0	COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,47P6K@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
TLS3_k127_5298818_1	1313301.AUGC01000005_gene366	1.912e-116	385.0	COG1785@1|root,COG1785@2|Bacteria,4NG3D@976|Bacteroidetes	976|Bacteroidetes	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
TLS3_k127_5298818_3	1123276.KB893246_gene817	7.032e-43	156.0	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,47R0I@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
TLS3_k127_5298818_0	1237149.C900_01133	1.646e-308	951.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,47M5V@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_5298818_4	1288963.ADIS_2163	3.022e-17	81.0	COG3169@1|root,COG3169@2|Bacteria,4NQH4@976|Bacteroidetes,47QJ9@768503|Cytophagia	976|Bacteroidetes	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
TLS3_k127_5309872_0	1121904.ARBP01000004_gene917	0.0	1038.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,4NFBV@976|Bacteroidetes,47K85@768503|Cytophagia	976|Bacteroidetes	EQ	Hydantoinase/oxoprolinase	-	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
TLS3_k127_5313758_2	1267211.KI669560_gene463	1.191e-107	354.0	COG0657@1|root,COG4099@1|root,COG0657@2|Bacteria,COG4099@2|Bacteria,4PKKH@976|Bacteroidetes,1J0WF@117747|Sphingobacteriia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,DLH
TLS3_k127_5313758_1	1123248.KB893327_gene789	5.434e-118	385.0	2957S@1|root,2ZSK8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5313758_0	929713.NIASO_04530	2.784e-204	639.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1INZD@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised conserved protein UCP016719	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
TLS3_k127_5314094_0	1237149.C900_01354	6.353e-255	800.0	COG2203@1|root,COG2203@2|Bacteria,4NICW@976|Bacteroidetes,47NI3@768503|Cytophagia	976|Bacteroidetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,PAS_9
TLS3_k127_5314094_3	1124780.ANNU01000015_gene1999	3.095e-35	141.0	2E3CB@1|root,32YBM@2|Bacteria,4NU80@976|Bacteroidetes,47Y2T@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
TLS3_k127_5314094_2	1237149.C900_01352	1.549e-61	216.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,47PZ4@768503|Cytophagia	976|Bacteroidetes	O	peptide methionine sulfoxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
TLS3_k127_5314094_1	1237149.C900_03711	5.745e-96	323.0	COG0121@1|root,COG0121@2|Bacteria	2|Bacteria	S	cellular modified histidine biosynthetic process	egtC	-	-	ko:K18802	-	-	-	-	ko00000	-	-	-	GATase_4
TLS3_k127_5315230_3	1124780.ANNU01000008_gene2664	1.534e-110	368.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,47ME3@768503|Cytophagia	976|Bacteroidetes	K	PFAM Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
TLS3_k127_5315230_2	1121859.KB890738_gene3045	6.479e-123	406.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,47JY8@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
TLS3_k127_5315230_1	1123276.KB893301_gene4227	3.419e-141	458.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,47KAR@768503|Cytophagia	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
TLS3_k127_5315230_4	616991.JPOO01000003_gene648	1.661e-105	348.0	COG5285@1|root,COG5285@2|Bacteria,4NFFH@976|Bacteroidetes	976|Bacteroidetes	Q	COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
TLS3_k127_5315230_0	1121904.ARBP01000049_gene4417	0.0	1040.0	COG3533@1|root,COG3533@2|Bacteria,4NG7T@976|Bacteroidetes,47NSK@768503|Cytophagia	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
TLS3_k127_5319328_0	616991.JPOO01000003_gene971	0.0	1070.0	COG1413@1|root,COG2133@1|root,COG3241@1|root,COG3250@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3241@2|Bacteria,COG3250@2|Bacteria,COG3828@2|Bacteria,4NQ6P@976|Bacteroidetes,1I34Z@117743|Flavobacteriia	976|Bacteroidetes	C	PFAM Copper binding proteins, plastocyanin azurin family	-	-	-	-	-	-	-	-	-	-	-	-	BetaGal_dom4_5,Copper-bind,ThuA
TLS3_k127_5319328_2	143224.JQMD01000002_gene1627	1.439e-137	442.0	COG1082@1|root,COG1082@2|Bacteria,4NI7Y@976|Bacteroidetes,1I0CB@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.30,5.1.3.31	ko:K18910	-	-	R10817,R10818	RC03111,RC03283	ko00000,ko01000	-	-	-	AP_endonuc_2
TLS3_k127_5319328_1	616991.JPOO01000003_gene969	6.759e-214	667.0	COG0673@1|root,COG0673@2|Bacteria,4NEJM@976|Bacteroidetes,1HZQQ@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_5319328_4	742741.HMPREF9475_00173	0.0009216	50.0	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,248C6@186801|Clostridia,2211R@1506553|Lachnoclostridium	186801|Clostridia	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	LysM,RHS_repeat
TLS3_k127_5319328_3	1121481.AUAS01000002_gene3227	3.18e-51	186.0	COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes,47JFT@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
TLS3_k127_5320438_6	1408433.JHXV01000006_gene2707	4.782e-11	63.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1I19R@117743|Flavobacteriia,2PAVI@246874|Cryomorphaceae	976|Bacteroidetes	F	Formyl transferase	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
TLS3_k127_5320438_2	1237149.C900_01023	9.466e-88	298.0	COG0382@1|root,COG0382@2|Bacteria,4NGNA@976|Bacteroidetes,47MCK@768503|Cytophagia	976|Bacteroidetes	H	PFAM UbiA prenyltransferase	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
TLS3_k127_5320438_4	1313301.AUGC01000010_gene900	2.094e-21	104.0	28M3Z@1|root,32ZEY@2|Bacteria,4NUZS@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5320438_1	1237149.C900_04463	9.457e-90	306.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,47JZY@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0104)	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
TLS3_k127_5320438_3	1237149.C900_04464	1.136e-55	196.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,47QA8@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
TLS3_k127_5320438_0	1237149.C900_04465	2.357e-92	312.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,47MNB@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
TLS3_k127_5320438_5	1123277.KB893185_gene3059	4.03e-17	82.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,47KUD@768503|Cytophagia	976|Bacteroidetes	G	PFAM Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
TLS3_k127_5320697_4	1296415.JACC01000029_gene2684	4.378e-09	57.0	COG2133@1|root,COG2133@2|Bacteria,4NJSW@976|Bacteroidetes,1I81Q@117743|Flavobacteriia,2YJ1N@290174|Aquimarina	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
TLS3_k127_5320697_3	1168034.FH5T_11765	7.841e-31	130.0	COG1426@1|root,COG1426@2|Bacteria	2|Bacteria	S	sequence-specific DNA binding	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25,HTH_3
TLS3_k127_5320697_1	1033739.CAEU01000031_gene1700	4.011e-42	160.0	COG0454@1|root,COG0456@2|Bacteria,1V3IC@1239|Firmicutes,4HH45@91061|Bacilli,26F7Q@186818|Planococcaceae	91061|Bacilli	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	yvbK	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
TLS3_k127_5320697_0	1443665.JACA01000059_gene1123	9.68e-53	201.0	COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,1HZK0@117743|Flavobacteriia,2YKJA@290174|Aquimarina	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_5320697_2	504472.Slin_2795	1.25e-36	153.0	COG1506@1|root,COG1506@2|Bacteria,4P5XA@976|Bacteroidetes	976|Bacteroidetes	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5321921_3	1313421.JHBV01000013_gene3789	3.977e-33	135.0	COG1595@1|root,COG1595@2|Bacteria,4NM7R@976|Bacteroidetes,1IYKQ@117747|Sphingobacteriia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_5321921_1	700598.Niako_3333	1.427e-112	372.0	COG0671@1|root,COG0671@2|Bacteria,4NHUS@976|Bacteroidetes	976|Bacteroidetes	I	Acid phosphatase	phoN	-	3.1.3.2	ko:K09474	ko00740,ko01100,ko02020,map00740,map01100,map02020	-	R00548	RC00017	ko00000,ko00001,ko01000	-	-	-	PAP2
TLS3_k127_5321921_0	1048983.EL17_09250	7.313e-179	569.0	COG1228@1|root,COG1228@2|Bacteria,4NGGD@976|Bacteroidetes,47R4K@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,SnoaL_2
TLS3_k127_5321921_2	1107311.Q767_12010	7.15e-66	237.0	COG1752@1|root,COG1752@2|Bacteria,4NUHF@976|Bacteroidetes,1HXTH@117743|Flavobacteriia	976|Bacteroidetes	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
TLS3_k127_5322599_2	1286632.P278_20780	7.917e-07	52.0	2A813@1|root,30X1F@2|Bacteria,4NP0A@976|Bacteroidetes,1I2B5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5322599_1	1123248.KB893386_gene1934	3.898e-40	154.0	COG0645@1|root,COG0645@2|Bacteria,4NSKU@976|Bacteroidetes,1J033@117747|Sphingobacteriia	976|Bacteroidetes	S	Chromatin associated protein KTI12	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
TLS3_k127_5322599_0	1048983.EL17_09875	2.698e-94	319.0	COG2187@1|root,COG2187@2|Bacteria,4NKD3@976|Bacteroidetes,47PG2@768503|Cytophagia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
TLS3_k127_5324348_0	1506583.JQJY01000002_gene1792	4.349e-277	864.0	COG3534@1|root,COG3534@2|Bacteria,4NGKW@976|Bacteroidetes,1HZE9@117743|Flavobacteriia,2NV03@237|Flavobacterium	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C,CBM_4_9
TLS3_k127_5324348_1	1123270.ATUR01000005_gene637	6.491e-42	160.0	COG1112@1|root,COG2251@1|root,COG1112@2|Bacteria,COG2251@2|Bacteria,1MWW9@1224|Proteobacteria,2TTSD@28211|Alphaproteobacteria,2K1G4@204457|Sphingomonadales	204457|Sphingomonadales	L	RNase_H superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,RNase_H_2
TLS3_k127_5333269_0	468059.AUHA01000003_gene1801	2.503e-149	484.0	COG4850@1|root,COG4850@2|Bacteria,4NFZ6@976|Bacteroidetes,1IT86@117747|Sphingobacteriia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
TLS3_k127_5333269_1	1229487.AMYW01000026_gene2694	8.533e-125	409.0	COG0859@1|root,COG0859@2|Bacteria,4NFVU@976|Bacteroidetes,1HXFI@117743|Flavobacteriia,2NUK0@237|Flavobacterium	976|Bacteroidetes	M	heptosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
TLS3_k127_5333269_2	153721.MYP_3327	1.428e-90	307.0	COG0702@1|root,COG0702@2|Bacteria,4NGMK@976|Bacteroidetes,47M3G@768503|Cytophagia	976|Bacteroidetes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
TLS3_k127_5333269_3	279010.BL03109	1.179e-29	122.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HH0A@91061|Bacilli,1ZHCV@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
TLS3_k127_5335256_3	1123277.KB893185_gene3033	2.249e-131	423.0	COG0627@1|root,COG0627@2|Bacteria,4NE7D@976|Bacteroidetes,47KC0@768503|Cytophagia	976|Bacteroidetes	S	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
TLS3_k127_5335256_1	929562.Emtol_3168	5.279e-174	550.0	COG0627@1|root,COG0627@2|Bacteria,4NIU8@976|Bacteroidetes,47NUH@768503|Cytophagia	976|Bacteroidetes	E	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
TLS3_k127_5335256_0	761193.Runsl_0491	2.488e-215	674.0	COG2851@1|root,COG2851@2|Bacteria,4NHKQ@976|Bacteroidetes,47MP2@768503|Cytophagia	976|Bacteroidetes	C	Na+/H+ antiporter family	-	-	-	ko:K03300	-	-	-	-	ko00000	2.A.11	-	-	CitMHS
TLS3_k127_5335256_2	760192.Halhy_4369	7.79e-172	545.0	COG3185@1|root,COG3185@2|Bacteria,4NGFD@976|Bacteroidetes,1IVVA@117747|Sphingobacteriia	976|Bacteroidetes	E	Pfam:DUF1446	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
TLS3_k127_53361_0	1392498.JQLH01000001_gene1026	1.064e-257	806.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1IC5Y@117743|Flavobacteriia,2PIIJ@252356|Maribacter	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
TLS3_k127_53361_1	1408813.AYMG01000017_gene5623	1.193e-28	116.0	COG2350@1|root,COG2350@2|Bacteria,4NVI4@976|Bacteroidetes,1IUFS@117747|Sphingobacteriia	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
TLS3_k127_5338794_2	1124780.ANNU01000008_gene2631	4.788e-86	289.0	COG1220@1|root,COG1220@2|Bacteria,4NFI2@976|Bacteroidetes,47JSG@768503|Cytophagia	976|Bacteroidetes	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
TLS3_k127_5338794_1	1237149.C900_01123	1.286e-99	334.0	COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,47KDM@768503|Cytophagia	976|Bacteroidetes	I	penicillin-binding protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_5338794_0	1237149.C900_01122	0.0	1254.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,47M84@768503|Cytophagia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
TLS3_k127_533886_1	1237149.C900_01547	7.34e-162	523.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,47KF5@768503|Cytophagia	976|Bacteroidetes	O	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
TLS3_k127_533886_2	1089547.KB913013_gene264	7.714e-148	478.0	COG1092@1|root,COG1092@2|Bacteria,4NG9S@976|Bacteroidetes,47M5H@768503|Cytophagia	976|Bacteroidetes	J	SAM-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
TLS3_k127_533886_0	1336803.PHEL49_1201	2.909e-192	610.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1HZT3@117743|Flavobacteriia,3VX1R@52959|Polaribacter	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_533886_3	616991.JPOO01000001_gene4356	2.943e-44	163.0	COG0715@1|root,COG0715@2|Bacteria,4NH2X@976|Bacteroidetes,1HYIQ@117743|Flavobacteriia	976|Bacteroidetes	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
TLS3_k127_5340936_1	1270196.JCKI01000002_gene559	1.999e-44	164.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1IV4X@117747|Sphingobacteriia	976|Bacteroidetes	K	CRP FNR family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TLS3_k127_5340936_2	1395587.P364_0100250	1.093e-35	139.0	COG0202@1|root,COG0202@2|Bacteria,1VD02@1239|Firmicutes,4HKNS@91061|Bacilli,27043@186822|Paenibacillaceae	91061|Bacilli	K	COG0202 DNA-directed RNA polymerase, alpha subunit 40 kD subunit	-	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_A_CTD
TLS3_k127_5340936_3	1173022.Cri9333_2605	1.57e-34	135.0	COG1359@1|root,COG1359@2|Bacteria,1G8H0@1117|Cyanobacteria,1HC7H@1150|Oscillatoriales	1117|Cyanobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
TLS3_k127_5340936_0	1121904.ARBP01000004_gene856	1.3e-125	413.0	COG1454@1|root,COG1454@2|Bacteria,4NE5Y@976|Bacteroidetes	976|Bacteroidetes	C	Dehydrogenase	-	-	1.1.1.61	ko:K18120,ko:K19954	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R01644	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
TLS3_k127_5340936_4	1121859.KB890758_gene1810	1.049e-31	130.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47P09@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
TLS3_k127_5345358_5	1519464.HY22_14155	1.24e-20	98.0	COG1377@1|root,COG1377@2|Bacteria	2|Bacteria	N	bacterial-type flagellum assembly	flhB	-	-	ko:K02401,ko:K13820	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1,Bac_export_2
TLS3_k127_5345358_4	509635.N824_09335	1.039e-34	143.0	29GF6@1|root,303CZ@2|Bacteria,4NR6I@976|Bacteroidetes,1IT48@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
TLS3_k127_5345358_3	1124780.ANNU01000051_gene2076	2.938e-82	287.0	28IVH@1|root,2Z8TX@2|Bacteria,4NEEW@976|Bacteroidetes,47N52@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
TLS3_k127_5345358_1	929556.Solca_4229	3.424e-140	452.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1IPUZ@117747|Sphingobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TLS3_k127_5345358_0	313606.M23134_03031	3.363e-165	530.0	COG1721@1|root,COG1721@2|Bacteria,4NE10@976|Bacteroidetes,47JBI@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TLS3_k127_5345358_2	1279009.ADICEAN_00472	2.246e-119	402.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,47KVM@768503|Cytophagia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
TLS3_k127_5359622_1	1120968.AUBX01000011_gene3193	1.648e-119	393.0	COG5000@1|root,COG5000@2|Bacteria,4NFFM@976|Bacteroidetes,47MZF@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
TLS3_k127_5359622_3	1237149.C900_05341	2.817e-53	191.0	COG0784@1|root,COG0784@2|Bacteria,4PNDD@976|Bacteroidetes,47YFG@768503|Cytophagia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_5359622_0	1120965.AUBV01000003_gene501	3.776e-141	474.0	COG4251@1|root,COG4251@2|Bacteria,4NGXA@976|Bacteroidetes,47NUK@768503|Cytophagia	976|Bacteroidetes	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9
TLS3_k127_5359622_2	1237149.C900_00553	3.935e-61	217.0	COG3637@1|root,COG3637@2|Bacteria,4NN3F@976|Bacteroidetes,47XR1@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
TLS3_k127_5364628_7	1237149.C900_02725	4.661e-38	146.0	COG2067@1|root,COG2067@2|Bacteria,4PKQK@976|Bacteroidetes,47XZ1@768503|Cytophagia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5364628_4	1237149.C900_02724	5.102e-84	284.0	COG3637@1|root,COG3637@2|Bacteria,4NF6B@976|Bacteroidetes,47PKF@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_5364628_1	1124780.ANNU01000005_gene2388	1.872e-113	370.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,47MC0@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
TLS3_k127_5364628_0	1237149.C900_02722	0.0	1134.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,47JEC@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
TLS3_k127_5364628_5	1237149.C900_02721	3.027e-69	239.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,47PD1@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane protein (OmpH-like)	skp	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TLS3_k127_5364628_6	1237149.C900_02720	1.374e-52	191.0	COG2825@1|root,COG2825@2|Bacteria,4NQHJ@976|Bacteroidetes,47QWE@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane protein (OmpH-like)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TLS3_k127_5364628_3	926549.KI421517_gene1841	1.025e-88	301.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,47KS4@768503|Cytophagia	976|Bacteroidetes	V	peptidase U61 LD-carboxypeptidase A	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
TLS3_k127_5364628_2	926549.KI421517_gene3975	1.006e-111	370.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,47JD1@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM flavoprotein, HI0933 family	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
TLS3_k127_536977_1	1237149.C900_00750	4.542e-128	422.0	COG1752@1|root,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,47QDC@768503|Cytophagia	976|Bacteroidetes	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
TLS3_k127_536977_0	1237149.C900_00749	3.299e-285	890.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
TLS3_k127_536977_3	1237149.C900_00748	6.895e-53	195.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2
TLS3_k127_536977_4	1237149.C900_04917	1.249e-40	160.0	2ETG7@1|root,338QK@2|Bacteria,4NW0M@976|Bacteroidetes,47X76@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_536977_2	1121957.ATVL01000006_gene2544	8.272e-80	273.0	COG1012@1|root,COG1012@2|Bacteria,4NGHD@976|Bacteroidetes,47KZA@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	alkH	-	1.2.1.3,1.2.1.68	ko:K00128,ko:K00154	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_5371579_5	1121904.ARBP01000060_gene1924	5.797e-10	60.0	COG3720@1|root,COG3720@2|Bacteria,4NEZU@976|Bacteroidetes,47MSN@768503|Cytophagia	976|Bacteroidetes	P	heme degradation protein	hmuS	-	-	ko:K07225	-	-	-	-	ko00000	-	-	-	HemS
TLS3_k127_5371579_1	1089547.KB913014_gene4931	6.791e-240	761.0	COG1629@1|root,COG4771@2|Bacteria,4NET0@976|Bacteroidetes,47KWB@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	hmuR	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_5371579_3	1237149.C900_05481	1.059e-59	213.0	2DBWZ@1|root,2ZBKJ@2|Bacteria,4NMS8@976|Bacteroidetes,47PF3@768503|Cytophagia	976|Bacteroidetes	S	HmuY protein	-	-	-	-	-	-	-	-	-	-	-	-	HmuY
TLS3_k127_5371579_4	471854.Dfer_3534	3.9e-11	66.0	2C7RG@1|root,33F0F@2|Bacteria,4NY3E@976|Bacteroidetes,47SYT@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5371579_0	1120968.AUBX01000011_gene3084	0.0	1109.0	COG4773@1|root,COG4773@2|Bacteria,4NF92@976|Bacteroidetes,47MSH@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM TonB-dependent siderophore receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_5371579_2	1185876.BN8_04598	2.871e-111	362.0	COG3182@1|root,COG3182@2|Bacteria,4NEXX@976|Bacteroidetes,47KYH@768503|Cytophagia	976|Bacteroidetes	S	Propeptide PepSY amd peptidase M4	-	-	-	-	-	-	-	-	-	-	-	-	PepSY,PepSY_TM
TLS3_k127_5374843_0	468059.AUHA01000003_gene1835	0.0	1137.0	COG1404@1|root,COG1404@2|Bacteria,4NHSQ@976|Bacteroidetes,1IWJ1@117747|Sphingobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_5374843_1	468059.AUHA01000003_gene1834	1.281e-87	304.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1IS6A@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg,TPR_12,TPR_8
TLS3_k127_5374843_2	1121011.AUCB01000029_gene2243	7.672e-19	87.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12,TPR_8
TLS3_k127_5376767_0	1237149.C900_01808	5.193e-102	340.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,47JXA@768503|Cytophagia	976|Bacteroidetes	S	PFAM YicC-like family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
TLS3_k127_5376767_1	504472.Slin_0733	1.416e-89	310.0	COG1914@1|root,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,47MUM@768503|Cytophagia	976|Bacteroidetes	P	PFAM natural resistance-associated macrophage protein	mntH	-	-	-	-	-	-	-	-	-	-	-	Nramp
TLS3_k127_5376767_2	1380600.AUYN01000001_gene2387	9.564e-70	244.0	28JI1@1|root,2Z9BG@2|Bacteria,4NMDW@976|Bacteroidetes,1I1PA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5384469_1	1121859.KB890754_gene794	7.514e-20	92.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47MQH@768503|Cytophagia	976|Bacteroidetes	S	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
TLS3_k127_5384469_0	504472.Slin_3180	2.445e-168	534.0	COG0667@1|root,COG0667@2|Bacteria,4NEDK@976|Bacteroidetes,47KXI@768503|Cytophagia	976|Bacteroidetes	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_5384469_2	236814.IX39_00270	4.927e-18	89.0	COG0745@1|root,COG0745@2|Bacteria,4NQNT@976|Bacteroidetes,1I3AQ@117743|Flavobacteriia,3ZS3I@59732|Chryseobacterium	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_5384487_0	929562.Emtol_3518	6.658e-226	718.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47MZ7@768503|Cytophagia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
TLS3_k127_5384487_1	1288963.ADIS_3540	8.929e-60	213.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,47K6V@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
TLS3_k127_5391944_0	760192.Halhy_0886	0.0	1487.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IWHI@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease PDZ domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
TLS3_k127_5391944_2	1237149.C900_01957	5.665e-111	364.0	COG3662@1|root,COG3662@2|Bacteria,4NEYP@976|Bacteroidetes,47NKS@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
TLS3_k127_5391944_4	1341181.FLJC2902T_16510	2.627e-45	167.0	2E6H5@1|root,3314C@2|Bacteria,4NVB7@976|Bacteroidetes,1I51P@117743|Flavobacteriia,2NWXH@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF2809)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2809
TLS3_k127_5391944_5	1166018.FAES_3430	3.416e-22	99.0	COG3250@1|root,COG3250@2|Bacteria,4NX3B@976|Bacteroidetes,47RUD@768503|Cytophagia	976|Bacteroidetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5391944_1	1121904.ARBP01000015_gene179	1.715e-181	598.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_5391944_3	745014.OMB55_00002900	1.646e-73	259.0	28N2R@1|root,2ZB8J@2|Bacteria,1R9S3@1224|Proteobacteria,1S09D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4405
TLS3_k127_5396601_3	531844.FIC_01664	2.961e-27	111.0	COG1905@1|root,COG1905@2|Bacteria,4NHIQ@976|Bacteroidetes,1HZPI@117743|Flavobacteriia	976|Bacteroidetes	C	NADH-quinone oxidoreductase subunit E	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
TLS3_k127_5396601_0	760192.Halhy_0319	1.728e-210	659.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1IR4T@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
TLS3_k127_5396601_2	153721.MYP_738	3.01e-53	192.0	COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,47PAN@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
TLS3_k127_5396601_1	468059.AUHA01000002_gene1084	4.705e-94	310.0	COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,1INQ8@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
TLS3_k127_5399065_0	1185876.BN8_04092	3.38e-142	469.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFTM@976|Bacteroidetes,47NS1@768503|Cytophagia	976|Bacteroidetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
TLS3_k127_5399065_1	1248916.ANFY01000004_gene1771	4.905e-13	70.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TQMV@28211|Alphaproteobacteria,2KD4R@204457|Sphingomonadales	204457|Sphingomonadales	G	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
TLS3_k127_5403047_2	1123277.KB893243_gene245	1.568e-38	145.0	COG0025@1|root,COG0025@2|Bacteria,4NSXF@976|Bacteroidetes,47RND@768503|Cytophagia	976|Bacteroidetes	P	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
TLS3_k127_5403047_0	553385.JEMF01000032_gene2586	4.251e-137	451.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MXA1@1224|Proteobacteria,1RQ1F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	transport	yehZ	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
TLS3_k127_5403047_1	1395513.P343_11285	3.897e-39	149.0	COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,26NQ3@186821|Sporolactobacillaceae	91061|Bacilli	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
TLS3_k127_54036_0	1237149.C900_04676	0.0	1483.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,47JP0@768503|Cytophagia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
TLS3_k127_54036_2	1237149.C900_04677	5.299e-50	179.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,47R37@768503|Cytophagia	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
TLS3_k127_54036_1	1121373.KB903663_gene1157	8.224e-75	252.0	COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,47PCE@768503|Cytophagia	976|Bacteroidetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
TLS3_k127_54036_3	313606.M23134_08218	4.758e-18	83.0	COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,47P7P@768503|Cytophagia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
TLS3_k127_5412201_3	1237149.C900_04704	5.711e-160	514.0	COG4797@1|root,COG4797@2|Bacteria,4PKQS@976|Bacteroidetes,47K4H@768503|Cytophagia	976|Bacteroidetes	D	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
TLS3_k127_5412201_4	929556.Solca_4351	4.319e-53	189.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1IT1E@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
TLS3_k127_5412201_2	1237149.C900_01774	1.258e-164	523.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,47JGZ@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
TLS3_k127_5412201_5	1237149.C900_02852	3.388e-47	174.0	2E0QA@1|root,32W90@2|Bacteria,4NUC6@976|Bacteroidetes,47RSZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5412201_1	1121904.ARBP01000010_gene2265	2.763e-171	550.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,47K9F@768503|Cytophagia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
TLS3_k127_5412201_6	929556.Solca_4338	1.732e-24	105.0	COG1254@1|root,COG1254@2|Bacteria,4NVB4@976|Bacteroidetes,1ITWQ@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
TLS3_k127_5412201_0	378806.STAUR_3216	1.105e-220	689.0	COG1012@1|root,COG1012@2|Bacteria,1R3TA@1224|Proteobacteria,42PG8@68525|delta/epsilon subdivisions,2WKCP@28221|Deltaproteobacteria,2YXAX@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.9	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	M00308,M00633	R01058	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_5426351_3	926549.KI421517_gene3689	9.916e-84	284.0	COG0398@1|root,COG0398@2|Bacteria,4NIT2@976|Bacteroidetes,47KFE@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
TLS3_k127_5426351_2	1408813.AYMG01000023_gene2037	4.648e-111	375.0	COG4244@1|root,COG4886@1|root,COG4244@2|Bacteria,COG4886@2|Bacteria,4NFES@976|Bacteroidetes,1IPVN@117747|Sphingobacteriia	976|Bacteroidetes	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,PSCyt1
TLS3_k127_5426351_1	929703.KE386491_gene3904	1.69e-120	393.0	COG1082@1|root,COG1082@2|Bacteria,4NFEA@976|Bacteroidetes,47K3N@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_5426351_0	525373.HMPREF0766_13832	3.565e-226	704.0	COG3119@1|root,COG3119@2|Bacteria,4NGVK@976|Bacteroidetes,1J0S3@117747|Sphingobacteriia	976|Bacteroidetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TLS3_k127_5429085_0	926556.Echvi_1296	2.271e-240	751.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,47K3J@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
TLS3_k127_5429085_2	1237149.C900_04484	1.004e-15	79.0	2E4W4@1|root,32ZQB@2|Bacteria,4NUZZ@976|Bacteroidetes,47RZI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5429085_1	1237149.C900_04485	1.84e-28	116.0	COG2013@1|root,COG2013@2|Bacteria,4NFNA@976|Bacteroidetes,47KS9@768503|Cytophagia	976|Bacteroidetes	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
TLS3_k127_5442481_0	1237149.C900_03868	1.066e-231	721.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,47JFM@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
TLS3_k127_5442481_2	1121904.ARBP01000028_gene1657	1.964e-171	561.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,47JA7@768503|Cytophagia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5442481_1	1237149.C900_03862	7.371e-206	646.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,47JM9@768503|Cytophagia	976|Bacteroidetes	L	PFAM MgsA AAA ATPase C terminal	ycaJ	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
TLS3_k127_5442481_5	925409.KI911562_gene2598	7.353e-39	157.0	COG1566@1|root,COG1566@2|Bacteria,4NH7M@976|Bacteroidetes,1IT7E@117747|Sphingobacteriia	976|Bacteroidetes	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
TLS3_k127_5442481_6	1121007.AUML01000006_gene3032	2.822e-24	106.0	COG0745@1|root,COG0745@2|Bacteria,4NV35@976|Bacteroidetes,1I3HP@117743|Flavobacteriia,2YJIM@290174|Aquimarina	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_5442481_4	313606.M23134_01760	4.547e-61	228.0	COG5002@1|root,COG5002@2|Bacteria,4PKXY@976|Bacteroidetes	976|Bacteroidetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9
TLS3_k127_5442481_3	485918.Cpin_0657	4.257e-67	229.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,1IR2E@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
TLS3_k127_5443344_1	1237149.C900_05208	1.304e-212	677.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,47M2A@768503|Cytophagia	976|Bacteroidetes	O	COGs COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
TLS3_k127_5443344_0	761193.Runsl_0088	5.717e-232	724.0	COG3669@1|root,COG4409@1|root,COG4692@1|root,COG3669@2|Bacteria,COG4409@2|Bacteria,COG4692@2|Bacteria,4NEDX@976|Bacteroidetes,47JNA@768503|Cytophagia	976|Bacteroidetes	G	Coagulation factor 5 8 type domain protein	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc
TLS3_k127_5445477_1	1237149.C900_01904	4.228e-126	427.0	COG0642@1|root,COG2205@2|Bacteria,4NTSQ@976|Bacteroidetes	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
TLS3_k127_5445477_0	1122176.KB903565_gene3409	6.948e-147	494.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1IRHX@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
TLS3_k127_5445477_2	1122176.KB903565_gene3409	4.728e-83	295.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1IRHX@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
TLS3_k127_5454834_0	1237149.C900_04526	4.453e-249	777.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,47KC6@768503|Cytophagia	976|Bacteroidetes	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
TLS3_k127_5454834_1	929703.KE386491_gene603	3.237e-177	563.0	COG1680@1|root,COG1680@2|Bacteria,4NHJN@976|Bacteroidetes,47JBV@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_5454834_3	1237149.C900_01018	3.578e-75	256.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,47P9Z@768503|Cytophagia	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
TLS3_k127_5454834_2	1120966.AUBU01000002_gene1914	2.356e-109	357.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,47JC6@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
TLS3_k127_5457741_4	501479.ACNW01000069_gene1285	4.795e-06	54.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	response regulator containing a CheY-like receiver domain and a GGDEF domain	pleD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
TLS3_k127_5457741_3	1237149.C900_05112	3.233e-33	132.0	COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,47S20@768503|Cytophagia	976|Bacteroidetes	S	PFAM Membrane protein of	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
TLS3_k127_5457741_1	1237149.C900_04925	2.313e-170	546.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,4NEQX@976|Bacteroidetes,47PIJ@768503|Cytophagia	976|Bacteroidetes	L	TIGRFAM exonuclease, DNA polymerase III, epsilon subunit family	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
TLS3_k127_5457741_2	1237149.C900_04913	4.065e-84	284.0	COG0639@1|root,COG0639@2|Bacteria,4NEQW@976|Bacteroidetes,47SZE@768503|Cytophagia	976|Bacteroidetes	T	Calcineurin-like phosphoesterase	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
TLS3_k127_5457741_0	1237149.C900_04914	2.225e-173	548.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,47JEN@768503|Cytophagia	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TLS3_k127_5464113_2	1123248.KB893327_gene788	3.781e-123	400.0	COG0258@1|root,COG0258@2|Bacteria	2|Bacteria	L	nuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
TLS3_k127_5464113_1	1123278.KB893563_gene4548	2.703e-272	846.0	COG3507@1|root,COG3507@2|Bacteria,4NGA5@976|Bacteroidetes,47K5U@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
TLS3_k127_5464113_0	1123277.KB893244_gene5195	2.381e-272	844.0	COG3507@1|root,COG3507@2|Bacteria,4NEVJ@976|Bacteroidetes,47JBZ@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,CBM_6,Glyco_hydro_43
TLS3_k127_5464113_3	1166018.FAES_2345	6.636e-76	257.0	COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes,47JFT@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
TLS3_k127_5466423_0	869213.JCM21142_1609	9.071e-183	598.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_5469003_2	1198452.Jab_2c33050	1.059e-83	279.0	COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,2VNA1@28216|Betaproteobacteria,476QD@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
TLS3_k127_5469003_3	468059.AUHA01000002_gene85	1.359e-12	72.0	2EC83@1|root,3366K@2|Bacteria,4NWPR@976|Bacteroidetes,1ITW7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5469003_0	1121904.ARBP01000001_gene5324	5.752e-237	757.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47KTF@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_5469003_1	1237149.C900_05324	4.022e-156	502.0	COG0477@1|root,COG2814@2|Bacteria,4NESW@976|Bacteroidetes,47JIH@768503|Cytophagia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_547817_1	1121456.ATVA01000019_gene1272	1.269e-70	265.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2M7T3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
TLS3_k127_547817_2	926562.Oweho_0926	6.925e-34	134.0	COG2199@1|root,COG3706@2|Bacteria,4PMSX@976|Bacteroidetes	976|Bacteroidetes	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_547817_0	1237149.C900_05815	8.959e-89	299.0	2DBU8@1|root,2ZB4S@2|Bacteria,4PKQU@976|Bacteroidetes,47Y2Z@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
TLS3_k127_5481892_1	1347393.HG726020_gene1714	6.123e-30	130.0	COG3279@1|root,COG3279@2|Bacteria,4NU8X@976|Bacteroidetes,2FR3K@200643|Bacteroidia,4APZC@815|Bacteroidaceae	976|Bacteroidetes	KT	COG3279 Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
TLS3_k127_5481892_0	471854.Dfer_5310	2.319e-154	501.0	COG4774@1|root,COG4774@2|Bacteria,4PKNF@976|Bacteroidetes,47XXH@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
TLS3_k127_548517_0	485918.Cpin_6251	5.23e-237	765.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,1IPUE@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc
TLS3_k127_548517_1	929562.Emtol_2134	1.38e-10	69.0	COG1119@1|root,COG1119@2|Bacteria,4NEWY@976|Bacteroidetes,47K9D@768503|Cytophagia	976|Bacteroidetes	P	ABC-type molybdenum transport system ATPase component photorepair protein PhrA	modF	-	-	ko:K05776	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	-	-	-	ABC_tran
TLS3_k127_5492975_0	504472.Slin_4791	1.954e-199	625.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,4NFE4@976|Bacteroidetes,47Y5G@768503|Cytophagia	976|Bacteroidetes	G	Maltogenic Amylase, C-terminal domain	-	-	3.2.1.1,3.2.1.10,5.4.99.16	ko:K01182,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R01557,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
TLS3_k127_5492975_1	485918.Cpin_5008	1.753e-103	346.0	COG0300@1|root,COG0300@2|Bacteria,4NIAI@976|Bacteroidetes,1IRS4@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
TLS3_k127_5492975_2	929556.Solca_1527	1.631e-10	65.0	COG3685@1|root,COG3685@2|Bacteria,4NMCT@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
TLS3_k127_5495454_0	1443665.JACA01000033_gene1789	1.305e-197	626.0	COG0464@1|root,COG0464@2|Bacteria,4NJBD@976|Bacteroidetes,1I7QT@117743|Flavobacteriia,2YIRG@290174|Aquimarina	976|Bacteroidetes	O	Holliday junction DNA helicase ruvB N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	AAA
TLS3_k127_5495454_1	1237149.C900_02129	2.642e-147	488.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_5499901_2	1237149.C900_02862	8.021e-40	151.0	2C6AJ@1|root,304IU@2|Bacteria,4NPQW@976|Bacteroidetes,47Q1B@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5499901_1	1227739.Hsw_0809	1.351e-127	417.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,47J92@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	eryC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_5499901_0	1237149.C900_02861	0.0	1296.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,47KCA@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
TLS3_k127_5536446_0	1122176.KB903536_gene1863	1.106e-102	342.0	COG3781@1|root,COG3781@2|Bacteria,4NEB1@976|Bacteroidetes,1IQHC@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG3781 membrane protein	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
TLS3_k127_5536446_1	886377.Murru_0351	1.633e-12	72.0	2ASGC@1|root,31HWH@2|Bacteria,4NR0Q@976|Bacteroidetes,1I25V@117743|Flavobacteriia	976|Bacteroidetes	S	Excinuclease ABC subunit B	-	-	-	-	-	-	-	-	-	-	-	-	TerB
TLS3_k127_5536446_2	103690.17132177	4.025e-07	62.0	COG0457@1|root,COG0457@2|Bacteria,1G1PV@1117|Cyanobacteria,1HJ37@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
TLS3_k127_5574945_8	1122621.ATZA01000039_gene2608	3.771e-71	241.0	COG0346@1|root,COG0346@2|Bacteria,4NNKT@976|Bacteroidetes,1IY97@117747|Sphingobacteriia	976|Bacteroidetes	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_5574945_10	761193.Runsl_5368	2.525e-45	169.0	COG0454@1|root,COG0456@2|Bacteria,4NTK3@976|Bacteroidetes,47R0F@768503|Cytophagia	976|Bacteroidetes	K	FR47-like protein	-	-	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7
TLS3_k127_5574945_7	761193.Runsl_2204	3.756e-72	255.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47PD7@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_5574945_3	761193.Runsl_1629	3.327e-99	328.0	COG1136@1|root,COG1136@2|Bacteria,4NFCG@976|Bacteroidetes,47KXC@768503|Cytophagia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	-	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
TLS3_k127_5574945_0	1239962.C943_01435	5.487e-172	548.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,47MB4@768503|Cytophagia	976|Bacteroidetes	M	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
TLS3_k127_5574945_5	929562.Emtol_1336	7.616e-82	286.0	COG0845@1|root,COG0845@2|Bacteria,4NITE@976|Bacteroidetes,47MHD@768503|Cytophagia	976|Bacteroidetes	M	Efflux transporter, RND family, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS3_k127_5574945_2	1124780.ANNU01000033_gene1296	1.028e-111	365.0	COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,47KEE@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
TLS3_k127_5574945_9	1237149.C900_04229	1.235e-49	180.0	COG1959@1|root,COG1959@2|Bacteria,4NNN2@976|Bacteroidetes,47P8M@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM Transcriptional regulator, Rrf2	cymR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
TLS3_k127_5574945_11	1408473.JHXO01000004_gene221	1.675e-26	113.0	COG0239@1|root,COG0239@2|Bacteria,4NV3N@976|Bacteroidetes,2FUP5@200643|Bacteroidia	976|Bacteroidetes	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
TLS3_k127_5574945_13	485918.Cpin_2572	2.897e-06	49.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IW8Y@117747|Sphingobacteriia	976|Bacteroidetes	L	resolvase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TLS3_k127_5574945_6	760192.Halhy_2095	5.282e-81	274.0	COG4832@1|root,COG4832@2|Bacteria,4NMQH@976|Bacteroidetes,1IRUW@117747|Sphingobacteriia	976|Bacteroidetes	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
TLS3_k127_5574945_4	1237149.C900_04765	9.144e-91	306.0	COG1974@1|root,COG1974@2|Bacteria,4PKQ7@976|Bacteroidetes,47P4U@768503|Cytophagia	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
TLS3_k127_5574945_1	388413.ALPR1_16264	3.021e-149	481.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,47JI6@768503|Cytophagia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
TLS3_k127_5574945_12	1121895.Q765_07890	2.297e-07	59.0	COG1514@1|root,COG1514@2|Bacteria,4PCEA@976|Bacteroidetes,1ID8T@117743|Flavobacteriia,2NXR1@237|Flavobacterium	976|Bacteroidetes	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
TLS3_k127_5575643_1	1250232.JQNJ01000001_gene1674	2.546e-77	260.0	COG2514@1|root,COG2514@2|Bacteria,4NMJC@976|Bacteroidetes,1I2B2@117743|Flavobacteriia	976|Bacteroidetes	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	catE	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
TLS3_k127_5575643_0	760192.Halhy_1785	4.955e-126	413.0	arCOG10456@1|root,2ZA6T@2|Bacteria,4NGZ2@976|Bacteroidetes,1ITDJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5575643_2	761193.Runsl_3454	3.649e-20	96.0	2CH44@1|root,33JG7@2|Bacteria,4PC1R@976|Bacteroidetes,47WPG@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5575643_3	471854.Dfer_4944	2.422e-10	68.0	COG2373@1|root,COG2373@2|Bacteria,4PKR7@976|Bacteroidetes,47QNG@768503|Cytophagia	976|Bacteroidetes	S	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_5578030_0	1416760.AYMS01000014_gene555	0.0	1140.0	COG0714@1|root,COG0714@2|Bacteria,4NGEG@976|Bacteroidetes,1HWP0@117743|Flavobacteriia,47HYS@76831|Myroides	976|Bacteroidetes	S	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5,DUF3686
TLS3_k127_5579631_10	1237149.C900_03280	7.942e-42	166.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,47JEP@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_5579631_16	1089547.KB913013_gene4367	8.002e-06	56.0	COG3850@1|root,COG5000@1|root,COG3850@2|Bacteria,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,47JEP@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_5579631_12	1239962.C943_02981	1.221e-28	119.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,47QXP@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
TLS3_k127_5579631_14	1288963.ADIS_4523	4.903e-16	80.0	2BT8H@1|root,32NDW@2|Bacteria,4P9FZ@976|Bacteroidetes,47R82@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5579631_9	1121875.KB907550_gene929	6.097e-65	226.0	COG2322@1|root,COG2322@2|Bacteria,4NM5N@976|Bacteroidetes,1I16X@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	yozB	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
TLS3_k127_5579631_15	153721.MYP_4740	5.973e-11	70.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,47XQN@768503|Cytophagia	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
TLS3_k127_5579631_11	1237149.C900_03275	2.148e-35	137.0	COG5605@1|root,COG5605@2|Bacteria,4NTVI@976|Bacteroidetes,47R14@768503|Cytophagia	976|Bacteroidetes	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
TLS3_k127_5579631_4	643867.Ftrac_3697	2.473e-121	392.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,47JVP@768503|Cytophagia	976|Bacteroidetes	C	cytochrome c oxidase subunit III	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
TLS3_k127_5579631_6	1237149.C900_03273	3.417e-92	305.0	COG1845@1|root,COG1845@2|Bacteria,4NFA7@976|Bacteroidetes,47NS2@768503|Cytophagia	976|Bacteroidetes	C	PFAM cytochrome c oxidase subunit III	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
TLS3_k127_5579631_3	1237149.C900_03272	6.073e-132	426.0	COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes,47MB0@768503|Cytophagia	976|Bacteroidetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
TLS3_k127_5579631_5	1237149.C900_03271	9.956e-105	349.0	COG1612@1|root,COG1612@2|Bacteria,4NEBR@976|Bacteroidetes,47JI1@768503|Cytophagia	976|Bacteroidetes	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
TLS3_k127_5579631_0	1237149.C900_03270	0.0	1097.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,47JBQ@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
TLS3_k127_5579631_2	1237149.C900_03269	5.948e-140	452.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,47JF8@768503|Cytophagia	976|Bacteroidetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
TLS3_k127_5579631_1	1237149.C900_03268	1.362e-189	601.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,47JUF@768503|Cytophagia	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5579631_8	1237149.C900_03267	2.687e-69	241.0	COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,47PEX@768503|Cytophagia	976|Bacteroidetes	C	PFAM Cytochrome C	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
TLS3_k127_5579631_7	1237149.C900_03266	3.023e-79	267.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,47K4U@768503|Cytophagia	976|Bacteroidetes	C	Quinol cytochrome c oxidoreductase membrane protein	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
TLS3_k127_5579631_13	1237149.C900_03265	1.001e-26	109.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,47K18@768503|Cytophagia	976|Bacteroidetes	C	PFAM Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
TLS3_k127_5590032_2	760192.Halhy_5136	3.339e-58	207.0	COG2133@1|root,COG3241@1|root,COG2133@2|Bacteria,COG3241@2|Bacteria,4NEMM@976|Bacteroidetes,1IUR8@117747|Sphingobacteriia	976|Bacteroidetes	CG	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
TLS3_k127_5590032_0	760192.Halhy_5414	5.392e-258	797.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,1IRE0@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_5590032_1	760192.Halhy_5413	2.925e-151	501.0	COG1413@1|root,COG1413@2|Bacteria,4NEZ7@976|Bacteroidetes,1IQ43@117747|Sphingobacteriia	976|Bacteroidetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,HEAT_2
TLS3_k127_5590032_3	32042.PstZobell_08062	2.1e-22	99.0	COG3335@1|root,COG3335@2|Bacteria,1MW8A@1224|Proteobacteria,1RY10@1236|Gammaproteobacteria,1Z3TW@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_28,HTH_29,HTH_33
TLS3_k127_5592542_2	985255.APHJ01000023_gene2682	1.909e-119	386.0	COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,1HZJA@117743|Flavobacteriia,2P7AT@244698|Gillisia	976|Bacteroidetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
TLS3_k127_5592542_0	1392489.JPOL01000003_gene262	3.042e-153	491.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HY4Z@117743|Flavobacteriia,2XK5I@283735|Leeuwenhoekiella	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TLS3_k127_5592542_3	985255.APHJ01000023_gene2684	2.244e-95	320.0	COG1721@1|root,COG1721@2|Bacteria,4NFX4@976|Bacteroidetes,1HXMB@117743|Flavobacteriia,2P7E0@244698|Gillisia	976|Bacteroidetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TLS3_k127_5592542_6	398720.MED217_05337	4.549e-34	146.0	28J48@1|root,2Z908@2|Bacteria,4PMAG@976|Bacteroidetes,1HZYH@117743|Flavobacteriia,2XK2R@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA
TLS3_k127_5592542_1	1237149.C900_01437	4.67e-145	488.0	COG0803@1|root,COG0803@2|Bacteria,4NHBN@976|Bacteroidetes,47KHC@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5592542_5	1237149.C900_01438	2.217e-79	287.0	28HMG@1|root,2Z7W1@2|Bacteria,4NI51@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5592542_4	1237149.C900_04861	1.249e-84	287.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,47NCP@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
TLS3_k127_5599372_1	1305737.JAFX01000001_gene11	5.392e-258	797.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,47JE5@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
TLS3_k127_5599372_2	1120966.AUBU01000002_gene2218	8.852e-80	272.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,47NEV@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
TLS3_k127_5599372_0	1237149.C900_03657	3.865e-303	941.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,47K9H@768503|Cytophagia	976|Bacteroidetes	L	DNA-directed DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
TLS3_k127_5618806_1	926549.KI421517_gene76	1.54e-242	758.0	COG4993@1|root,COG4993@2|Bacteria,4NINH@976|Bacteroidetes,47MZW@768503|Cytophagia	976|Bacteroidetes	G	PQQ-like domain	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
TLS3_k127_5618806_0	1237149.C900_01151	0.0	1296.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,47JNC@768503|Cytophagia	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
TLS3_k127_5618806_2	1121930.AQXG01000008_gene209	3.389e-114	384.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes	976|Bacteroidetes	V	permease	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_5622085_0	929556.Solca_0073	1.572e-81	291.0	COG0477@1|root,COG2814@2|Bacteria,4P1E4@976|Bacteroidetes	976|Bacteroidetes	EGP	Major facilitator Superfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
TLS3_k127_5622085_1	1341181.FLJC2902T_04190	3.687e-81	280.0	COG1566@1|root,COG1566@2|Bacteria,4NEQJ@976|Bacteroidetes,1HZG9@117743|Flavobacteriia,2P033@237|Flavobacterium	976|Bacteroidetes	V	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS3_k127_5627542_2	991.IW20_22135	2.592e-38	146.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,1I05F@117743|Flavobacteriia,2NUCF@237|Flavobacterium	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	czcB	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
TLS3_k127_5627542_0	1121481.AUAS01000001_gene4468	0.0	1536.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,47JC4@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
TLS3_k127_5627542_3	1358423.N180_06695	9.939e-09	64.0	2E6GS@1|root,3313Z@2|Bacteria,4P87X@976|Bacteroidetes,1IZMD@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5627542_1	700598.Niako_0098	4.674e-145	463.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,4NFUD@976|Bacteroidetes,1IPBH@117747|Sphingobacteriia	976|Bacteroidetes	H	UBA THIF-type NAD FAD binding protein	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
TLS3_k127_5633677_3	504487.JCM19302_3076	1.066e-29	122.0	COG0720@1|root,COG0720@2|Bacteria,4NNIS@976|Bacteroidetes,1I1ZF@117743|Flavobacteriia	976|Bacteroidetes	H	synthase	ygcM	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
TLS3_k127_5633677_1	1237149.C900_00316	1.911e-111	363.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,47MMS@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
TLS3_k127_5633677_2	1237149.C900_00315	3.482e-37	146.0	COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,47QE6@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
TLS3_k127_5633677_0	1237149.C900_03056	1.228e-247	768.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,47KF9@768503|Cytophagia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
TLS3_k127_5635463_0	1235755.ANAM01000002_gene21	3.463e-194	618.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,4GX0U@90964|Staphylococcaceae	91061|Bacilli	U	Sodium alanine symporter family protein	yrbD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
TLS3_k127_5635463_5	1250278.JQNQ01000001_gene3316	3.233e-07	63.0	COG2202@1|root,COG3437@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,4PMSQ@976|Bacteroidetes,1HZN0@117743|Flavobacteriia	976|Bacteroidetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_3,PAS_9,Response_reg
TLS3_k127_5635463_4	1121904.ARBP01000018_gene2606	5.49e-36	154.0	COG4191@1|root,COG4191@2|Bacteria,4NE4T@976|Bacteroidetes,47K96@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_5635463_2	153721.MYP_2731	2.218e-142	473.0	COG4585@1|root,COG4585@2|Bacteria,4NJN6@976|Bacteroidetes,47PJ6@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TLS3_k127_5635463_3	153721.MYP_2732	4.156e-81	277.0	COG2197@1|root,COG2197@2|Bacteria,4NKX7@976|Bacteroidetes,47QZF@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_5635463_1	700598.Niako_5315	1.414e-189	603.0	COG1167@1|root,COG1167@2|Bacteria,4NGKQ@976|Bacteroidetes,1IPKF@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
TLS3_k127_5635463_6	1056512.D515_04068	4.633e-05	46.0	COG0454@1|root,COG0456@2|Bacteria,1N41Y@1224|Proteobacteria,1SD94@1236|Gammaproteobacteria,1XZFI@135623|Vibrionales	135623|Vibrionales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_5648538_3	1279009.ADICEAN_03511	3.748e-66	234.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,47NST@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
TLS3_k127_5648538_0	1237149.C900_04944	1.393e-201	642.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,47JTG@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
TLS3_k127_5648538_4	1237149.C900_04943	2.944e-29	120.0	COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,47S3A@768503|Cytophagia	976|Bacteroidetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
TLS3_k127_5648538_5	866536.Belba_1807	2.255e-16	79.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,47RUZ@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
TLS3_k127_5648538_1	1237149.C900_04938	2.392e-137	444.0	COG0524@1|root,COG0524@2|Bacteria,4NIHI@976|Bacteroidetes,47NUW@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the carbohydrate kinase PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
TLS3_k127_5648538_2	1237149.C900_04937	2.038e-112	370.0	COG0584@1|root,COG0584@2|Bacteria,4NGI1@976|Bacteroidetes,47MFN@768503|Cytophagia	976|Bacteroidetes	C	PFAM Glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,Phytase-like
TLS3_k127_5665404_3	398720.MED217_11609	3.82e-52	188.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia,2XI0Q@283735|Leeuwenhoekiella	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
TLS3_k127_5665404_1	1237149.C900_04045	3.791e-73	258.0	COG3595@1|root,COG3595@2|Bacteria,4NMHT@976|Bacteroidetes,47PEC@768503|Cytophagia	976|Bacteroidetes	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
TLS3_k127_5665404_0	1279009.ADICEAN_02528	7.503e-255	804.0	COG0475@1|root,COG0475@2|Bacteria,4NF11@976|Bacteroidetes,47KD1@768503|Cytophagia	976|Bacteroidetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
TLS3_k127_5665404_2	1121904.ARBP01000006_gene3740	5.234e-54	194.0	COG0457@1|root,COG0457@2|Bacteria,4PBAK@976|Bacteroidetes,47VJ2@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5670105_2	1121373.KB903632_gene524	8.055e-05	46.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,47K9B@768503|Cytophagia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
TLS3_k127_5670105_0	1237149.C900_00265	4.028e-184	580.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,47JZ3@768503|Cytophagia	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
TLS3_k127_5670105_1	1237149.C900_00264	1.626e-26	110.0	COG0694@1|root,COG0694@2|Bacteria,4NSHJ@976|Bacteroidetes,47RA0@768503|Cytophagia	976|Bacteroidetes	O	NifU domain protein	nfuA	-	-	-	-	-	-	-	-	-	-	-	NifU
TLS3_k127_5671918_1	1047013.AQSP01000142_gene184	1.574e-112	392.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_5671918_0	1296416.JACB01000044_gene4938	2.674e-142	463.0	COG4941@1|root,COG4941@2|Bacteria,4NGCS@976|Bacteroidetes,1I06D@117743|Flavobacteriia,2YHFP@290174|Aquimarina	976|Bacteroidetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_5681843_2	761193.Runsl_5360	3.211e-71	254.0	COG4636@1|root,COG4636@2|Bacteria,4NFKR@976|Bacteroidetes,47K44@768503|Cytophagia	976|Bacteroidetes	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS3_k127_5681843_1	1237149.C900_00456	3.032e-105	346.0	COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,47KEV@768503|Cytophagia	976|Bacteroidetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
TLS3_k127_5681843_3	1120966.AUBU01000006_gene3494	2.377e-20	101.0	28M3Z@1|root,32ZEY@2|Bacteria,4NUZS@976|Bacteroidetes,47SGM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5681843_0	1237149.C900_04328	5.419e-146	466.0	COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,47KE8@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
TLS3_k127_5682954_3	714943.Mucpa_7117	1.012e-115	377.0	COG1028@1|root,COG1028@2|Bacteria,4NFU6@976|Bacteroidetes,1INPC@117747|Sphingobacteriia	976|Bacteroidetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_5682954_1	714943.Mucpa_7116	3.831e-159	505.0	COG4977@1|root,COG4977@2|Bacteria,4PMWI@976|Bacteroidetes,1J0ND@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_5682954_0	926549.KI421517_gene3363	3.289e-167	532.0	COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,47K9S@768503|Cytophagia	976|Bacteroidetes	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
TLS3_k127_5682954_2	1237149.C900_05740	1.677e-148	479.0	COG4242@1|root,COG4242@2|Bacteria,4NIBM@976|Bacteroidetes,47K6W@768503|Cytophagia	976|Bacteroidetes	PQ	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
TLS3_k127_5682954_4	1121007.AUML01000037_gene2004	6.843e-38	144.0	COG1116@1|root,COG1116@2|Bacteria,4NNV0@976|Bacteroidetes,1I89B@117743|Flavobacteriia,2YJA2@290174|Aquimarina	976|Bacteroidetes	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.25	ko:K02045,ko:K02049	ko00920,ko02010,map00920,map02010	M00185,M00188	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran
TLS3_k127_5683274_0	1185876.BN8_01492	5.138e-67	231.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,47JS7@768503|Cytophagia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
TLS3_k127_5688419_0	1237149.C900_02882	1.995e-140	449.0	COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,47K8P@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
TLS3_k127_5688419_3	1237149.C900_02880	5.202e-60	211.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,47QMM@768503|Cytophagia	976|Bacteroidetes	F	Pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
TLS3_k127_5688419_2	1305737.JAFX01000001_gene1205	1.452e-68	235.0	COG1522@1|root,COG1522@2|Bacteria,4NMYA@976|Bacteroidetes,47P8E@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K03719,ko:K05800	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
TLS3_k127_5688419_1	1227739.Hsw_0817	5e-73	258.0	COG0438@1|root,COG0438@2|Bacteria,4PAVB@976|Bacteroidetes,47UKE@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_5689792_0	1237149.C900_04102	7.739e-179	590.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,47KQP@768503|Cytophagia	976|Bacteroidetes	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
TLS3_k127_5689792_1	1237149.C900_04101	9.998e-74	251.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,47JX0@768503|Cytophagia	976|Bacteroidetes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
TLS3_k127_5694133_2	1123248.KB893325_gene1167	5.922e-83	283.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1IREC@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
TLS3_k127_5694133_1	1123248.KB893325_gene1166	1.092e-160	509.0	KOG1573@1|root,2Z822@2|Bacteria,4NFQF@976|Bacteroidetes,1IPN5@117747|Sphingobacteriia	976|Bacteroidetes	S	Inositol oxygenase	-	-	1.13.99.1	ko:K00469	ko00053,ko00562,map00053,map00562	-	R01184	RC00465	ko00000,ko00001,ko01000	-	-	-	MIOX
TLS3_k127_5694133_0	929713.NIASO_01600	3.775e-226	707.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1IPDT@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
TLS3_k127_5700812_1	643867.Ftrac_1169	1.622e-68	243.0	COG0682@1|root,COG0682@2|Bacteria,4NFP7@976|Bacteroidetes,47KQC@768503|Cytophagia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
TLS3_k127_5700812_0	1237149.C900_01627	1.202e-138	455.0	COG4775@1|root,COG4775@2|Bacteria,4NF9Y@976|Bacteroidetes,47KUK@768503|Cytophagia	976|Bacteroidetes	M	PFAM surface antigen variable number repeat	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
TLS3_k127_5700812_2	546275.FUSPEROL_01630	5.63e-09	60.0	COG2849@1|root,COG2849@2|Bacteria,37AI5@32066|Fusobacteria	32066|Fusobacteria	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_5705272_1	1279009.ADICEAN_03237	8.339e-06	49.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,47KA7@768503|Cytophagia	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
TLS3_k127_5705272_0	1356852.N008_14405	3.681e-234	739.0	COG0438@1|root,COG0438@2|Bacteria,4PKQN@976|Bacteroidetes,47K56@768503|Cytophagia	976|Bacteroidetes	M	PFAM glycogen synthase	-	-	2.4.1.11	ko:K00693	ko00500,ko01100,ko04151,ko04152,ko04910,ko04922,ko04931,map00500,map01100,map04151,map04152,map04910,map04922,map04931	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT3	-	Glycogen_syn
TLS3_k127_5710025_3	485918.Cpin_1072	1.229e-26	116.0	2CBRE@1|root,31J72@2|Bacteria,4NS59@976|Bacteroidetes,1IYR4@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_5710025_2	1189612.A33Q_1038	2.414e-52	196.0	COG2378@1|root,COG2378@2|Bacteria,4NN6R@976|Bacteroidetes,47QC2@768503|Cytophagia	976|Bacteroidetes	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
TLS3_k127_5710025_1	991.IW20_09940	5.959e-84	294.0	COG4487@1|root,COG4487@2|Bacteria,4NGZ9@976|Bacteroidetes,1HZ50@117743|Flavobacteriia,2NV85@237|Flavobacterium	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2130)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2130
TLS3_k127_5710025_0	760192.Halhy_3609	9.182e-115	374.0	COG0673@1|root,COG0673@2|Bacteria,4NF96@976|Bacteroidetes,1IQ5B@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_5711075_7	1120968.AUBX01000011_gene3235	2.801e-59	207.0	COG4589@1|root,COG4589@2|Bacteria,4NIPM@976|Bacteroidetes,47KPM@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
TLS3_k127_5711075_4	153721.MYP_3566	1.979e-71	264.0	COG2202@1|root,COG2203@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,4NICW@976|Bacteroidetes,47KTQ@768503|Cytophagia	976|Bacteroidetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	GAF_2,PAS_3,PAS_9
TLS3_k127_5711075_0	1237149.C900_02782	2.455e-234	729.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,47K4Z@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
TLS3_k127_5711075_3	1189612.A33Q_2291	6.429e-90	301.0	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,47MWN@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
TLS3_k127_5711075_1	1239962.C943_04256	2.367e-161	515.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,47JP1@768503|Cytophagia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_5711075_2	388413.ALPR1_20173	4.298e-134	450.0	COG4796@1|root,COG4796@2|Bacteria,4PM2P@976|Bacteroidetes,47Y0K@768503|Cytophagia	976|Bacteroidetes	U	Type ii and iii secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,DUF4974,STN
TLS3_k127_5711075_5	1189612.A33Q_1645	3.724e-62	227.0	COG3712@1|root,COG3712@2|Bacteria,4NMA2@976|Bacteroidetes,47PEK@768503|Cytophagia	976|Bacteroidetes	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
TLS3_k127_5711075_6	1048983.EL17_18910	3.678e-60	213.0	COG1595@1|root,COG1595@2|Bacteria,4NNBY@976|Bacteroidetes,47PH5@768503|Cytophagia	976|Bacteroidetes	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_5711075_8	1120968.AUBX01000015_gene3653	1.178e-09	65.0	COG1564@1|root,COG1564@2|Bacteria,4NGJH@976|Bacteroidetes,47MV1@768503|Cytophagia	976|Bacteroidetes	H	thiamine pyrophosphokinase	-	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
TLS3_k127_5721779_0	1185876.BN8_00899	6.408e-179	588.0	COG0577@1|root,COG0577@2|Bacteria,4NM3D@976|Bacteroidetes,47JF6@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_5721779_1	1123277.KB893180_gene2471	4.732e-81	272.0	COG2730@1|root,COG2730@2|Bacteria,4NGAC@976|Bacteroidetes,47MSS@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
TLS3_k127_5724844_0	1237149.C900_02080	2.991e-54	199.0	COG4585@1|root,COG4585@2|Bacteria,4NNE1@976|Bacteroidetes,47PFT@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TLS3_k127_5725329_2	1237149.C900_00485	1.727e-123	398.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,47MF7@768503|Cytophagia	976|Bacteroidetes	IQ	TIGRFAM 3-oxoacyl-(acyl-carrier-protein) reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_5725329_4	760192.Halhy_4272	7.92e-35	139.0	COG2318@1|root,COG2318@2|Bacteria,4NRAP@976|Bacteroidetes,1IUMH@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_5725329_0	1279009.ADICEAN_00481	7.206e-238	740.0	COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,47M8Z@768503|Cytophagia	976|Bacteroidetes	E	PFAM Cys Met metabolism PLP-dependent enzyme	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
TLS3_k127_5725329_1	1089547.KB913013_gene3855	1.447e-139	452.0	COG2021@1|root,COG2021@2|Bacteria,4NFG2@976|Bacteroidetes,47KMZ@768503|Cytophagia	976|Bacteroidetes	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
TLS3_k127_5725329_3	485918.Cpin_1962	9.608e-83	280.0	COG0460@1|root,COG0460@2|Bacteria,4NHRC@976|Bacteroidetes,1IPM4@117747|Sphingobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
TLS3_k127_5732818_0	1121904.ARBP01000015_gene179	9.923e-149	498.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_5733314_0	1123248.KB893381_gene965	6.113e-160	508.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,1IP70@117747|Sphingobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
TLS3_k127_5733314_2	700598.Niako_5907	3.571e-55	201.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,CBM9_2,DUF362
TLS3_k127_5733314_1	616991.JPOO01000003_gene2353	2.475e-159	511.0	COG1921@1|root,COG1921@2|Bacteria,4NIIG@976|Bacteroidetes,1I090@117743|Flavobacteriia	976|Bacteroidetes	H	L-seryl-tRNA selenium transferase	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
TLS3_k127_5734010_10	1237149.C900_04494	2.64e-47	173.0	2C88U@1|root,2ZAHP@2|Bacteria,4NK63@976|Bacteroidetes,47NBI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
TLS3_k127_5734010_6	926549.KI421517_gene1156	1.904e-117	384.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,47JJ8@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
TLS3_k127_5734010_11	1237149.C900_04492	1.261e-39	151.0	2E4SF@1|root,32ZKW@2|Bacteria,4NV4G@976|Bacteroidetes,47RXS@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4783
TLS3_k127_5734010_1	1237149.C900_04626	1.888e-245	767.0	COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,47K1F@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
TLS3_k127_5734010_12	643867.Ftrac_2140	1.805e-17	89.0	29KB5@1|root,3078F@2|Bacteria,4NNX1@976|Bacteroidetes,47Q3E@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5734010_0	1237149.C900_04623	5.118e-246	772.0	COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,47M5S@768503|Cytophagia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
TLS3_k127_5734010_9	1123277.KB893219_gene6196	5.197e-49	179.0	COG0735@1|root,COG0735@2|Bacteria,4NSES@976|Bacteroidetes,47PU3@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the Fur family	zur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
TLS3_k127_5734010_5	1237149.C900_04621	2.255e-129	420.0	COG0861@1|root,COG0861@2|Bacteria,4NH7P@976|Bacteroidetes,47N45@768503|Cytophagia	976|Bacteroidetes	P	PFAM Integral membrane protein TerC	ygjT	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
TLS3_k127_5734010_8	1237149.C900_04619	9.449e-72	245.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,47PQS@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
TLS3_k127_5734010_3	1237149.C900_04618	5.123e-171	543.0	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,47JH8@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
TLS3_k127_5734010_4	1237149.C900_04617	9.539e-157	515.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,4PM5K@976|Bacteroidetes,47MDR@768503|Cytophagia	976|Bacteroidetes	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT,HEAT_2,Pro_isomerase
TLS3_k127_5734010_2	1237149.C900_03447	1.49e-205	649.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
TLS3_k127_573670_0	700598.Niako_4335	2.759e-241	758.0	COG1032@1|root,COG1032@2|Bacteria,4NH8Y@976|Bacteroidetes,1IRE5@117747|Sphingobacteriia	976|Bacteroidetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
TLS3_k127_573670_1	945713.IALB_2761	2.899e-58	209.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	prmC	-	2.1.1.297,2.7.7.87	ko:K02493,ko:K07566	-	-	R10463,R10806	RC00003,RC00745,RC03279	ko00000,ko01000,ko03009,ko03012,ko03016	-	-	-	MTS
TLS3_k127_573670_2	1185876.BN8_00851	2.636e-45	170.0	COG3595@1|root,COG3595@2|Bacteria,4NJCC@976|Bacteroidetes,47MIA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
TLS3_k127_5739651_2	929556.Solca_2279	2.239e-55	198.0	COG0730@1|root,COG1648@1|root,COG0730@2|Bacteria,COG1648@2|Bacteria,4NI81@976|Bacteroidetes,1IPH7@117747|Sphingobacteriia	976|Bacteroidetes	H	membrane transporter protein	cysG	-	1.3.1.76,4.99.1.4	ko:K02304,ko:K07090	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M,TauE
TLS3_k127_5739651_1	153721.MYP_3753	1.68e-76	264.0	COG2067@1|root,COG2067@2|Bacteria,4NN8Q@976|Bacteroidetes,47PNT@768503|Cytophagia	976|Bacteroidetes	I	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
TLS3_k127_5739651_0	1122605.KB893647_gene282	0.0	1096.0	COG1629@1|root,COG4771@2|Bacteria,4PKE0@976|Bacteroidetes,1IPE3@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_5741681_3	1185876.BN8_06593	7.455e-43	162.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,47K5B@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
TLS3_k127_5741681_1	945713.IALB_2577	1.452e-153	502.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,HYR,LTD,P_proprotein
TLS3_k127_5741681_2	1237149.C900_01571	4.108e-97	322.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,47KMH@768503|Cytophagia	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
TLS3_k127_5741681_0	1237149.C900_01570	0.0	1110.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,47K7C@768503|Cytophagia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
TLS3_k127_5741681_4	1237149.C900_01569	8.768e-36	142.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,47R7I@768503|Cytophagia	976|Bacteroidetes	T	PFAM Phosphoglycerate mutase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
TLS3_k127_5751673_4	929562.Emtol_0361	8.758e-128	415.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,47N92@768503|Cytophagia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_5751673_2	1237149.C900_03122	1.756e-161	513.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,47KTK@768503|Cytophagia	976|Bacteroidetes	S	PFAM ATPase associated with various cellular activities	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TLS3_k127_5751673_3	1237149.C900_03123	1.71e-158	512.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,47JPW@768503|Cytophagia	976|Bacteroidetes	O	peptidyl-prolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
TLS3_k127_5751673_5	1237149.C900_03124	4.924e-101	338.0	COG0760@1|root,COG0760@2|Bacteria,4NG2P@976|Bacteroidetes,47NE3@768503|Cytophagia	976|Bacteroidetes	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
TLS3_k127_5751673_1	1237149.C900_03125	1.12e-175	572.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,47K78@768503|Cytophagia	976|Bacteroidetes	O	peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
TLS3_k127_5751673_6	1237149.C900_03126	2.213e-39	151.0	COG2172@1|root,COG2172@2|Bacteria,4NV3J@976|Bacteroidetes,47RU2@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
TLS3_k127_5751673_7	1237149.C900_03127	5.063e-37	142.0	COG1366@1|root,COG1366@2|Bacteria,4NVHQ@976|Bacteroidetes,47RVX@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
TLS3_k127_5751673_0	1237149.C900_03128	1.153e-239	757.0	COG2208@1|root,COG2208@2|Bacteria,4NJMJ@976|Bacteroidetes,47JNJ@768503|Cytophagia	976|Bacteroidetes	KT	PFAM Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,SpoIIE
TLS3_k127_5755739_3	1121904.ARBP01000011_gene1491	2.241e-51	187.0	COG2197@1|root,COG2197@2|Bacteria,4NN2R@976|Bacteroidetes,47W05@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	narL	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_5755739_5	1396141.BATP01000018_gene1537	8.238e-05	49.0	2FI25@1|root,349V0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5755739_2	1121904.ARBP01000060_gene1921	4.866e-72	252.0	COG4558@1|root,COG4558@2|Bacteria,4NH3G@976|Bacteroidetes,47K93@768503|Cytophagia	976|Bacteroidetes	P	ABC-type hemin transport system, periplasmic component	hmuT	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
TLS3_k127_5755739_0	1121904.ARBP01000060_gene1922	3.63e-97	329.0	COG0609@1|root,COG0609@2|Bacteria,4NEDU@976|Bacteroidetes,47JPP@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	hmuU	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
TLS3_k127_5755739_1	1121904.ARBP01000060_gene1923	9.826e-73	253.0	COG4559@1|root,COG4559@2|Bacteria,4NK28@976|Bacteroidetes,47PKH@768503|Cytophagia	976|Bacteroidetes	P	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system	hmuV	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
TLS3_k127_5755739_4	1189612.A33Q_1376	1.309e-24	105.0	COG3720@1|root,COG3720@2|Bacteria,4NEZU@976|Bacteroidetes,47MSN@768503|Cytophagia	976|Bacteroidetes	P	heme degradation protein	hmuS	-	-	ko:K07225	-	-	-	-	ko00000	-	-	-	HemS
TLS3_k127_5759422_3	485918.Cpin_0657	5.991e-64	224.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,1IR2E@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
TLS3_k127_5759422_1	649349.Lbys_0105	5.781e-80	271.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,47NY1@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
TLS3_k127_5759422_4	1123276.KB893279_gene2120	1.156e-49	183.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,47P92@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
TLS3_k127_5759422_0	1267211.KI669560_gene1776	2.539e-171	550.0	COG0534@1|root,COG0534@2|Bacteria,4NFIR@976|Bacteroidetes,1IXI6@117747|Sphingobacteriia	976|Bacteroidetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
TLS3_k127_5759422_2	1237149.C900_02113	1.844e-73	254.0	COG0823@1|root,COG0823@2|Bacteria,4PME8@976|Bacteroidetes,47Y2Q@768503|Cytophagia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5792676_2	880070.Cycma_0657	1.394e-21	97.0	COG0009@1|root,COG0009@2|Bacteria,4NF5U@976|Bacteroidetes,47KX9@768503|Cytophagia	976|Bacteroidetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua5	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
TLS3_k127_5792676_0	929556.Solca_1205	1.034e-125	408.0	COG2367@1|root,COG2367@2|Bacteria,4NDYP@976|Bacteroidetes,1INNE@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
TLS3_k127_5792676_3	1166018.FAES_3030	1.708e-18	94.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,47M7Q@768503|Cytophagia	976|Bacteroidetes	KMT	PFAM BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
TLS3_k127_5792676_1	1396141.BATP01000039_gene1434	4.727e-22	98.0	COG1051@1|root,COG1051@2|Bacteria,46VWV@74201|Verrucomicrobia,2IVYW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_579357_0	1237149.C900_00745	0.0	1082.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,47KBD@768503|Cytophagia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2
TLS3_k127_579357_1	1123248.KB893325_gene1171	1.56e-122	410.0	COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,4NHVG@976|Bacteroidetes,1IQPM@117747|Sphingobacteriia	976|Bacteroidetes	C	Membrane-bound dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH,HEAT_2
TLS3_k127_5807619_0	866536.Belba_0616	0.0	1577.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,47JWU@768503|Cytophagia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
TLS3_k127_5807619_4	1237149.C900_03145	1.1e-82	281.0	COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,47MEJ@768503|Cytophagia	976|Bacteroidetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
TLS3_k127_5807619_1	925409.KI911562_gene60	1.895e-230	721.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPK3@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
TLS3_k127_5807619_3	1237149.C900_04521	9.602e-85	286.0	COG0745@1|root,COG0745@2|Bacteria,4NM5Q@976|Bacteroidetes,47PED@768503|Cytophagia	976|Bacteroidetes	K	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_5807619_2	1237149.C900_04522	3.413e-159	511.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,47M71@768503|Cytophagia	976|Bacteroidetes	T	Signal transduction histidine kinase	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_5807619_5	761193.Runsl_3819	0.0001018	47.0	2CG1Y@1|root,333IH@2|Bacteria,4NVMK@976|Bacteroidetes,47RKN@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
TLS3_k127_5814804_7	1237149.C900_01589	1.704e-38	151.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47N4N@768503|Cytophagia	976|Bacteroidetes	T	PFAM histidine kinase internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_5814804_3	1237149.C900_01588	2.755e-116	391.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	3.4.11.2,3.4.24.3	ko:K01256,ko:K01387	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002,ko02042	-	-	-	HEAT_2,HEAT_PBS,Peptidase_M1,Peptidase_M9,Peptidase_M9_N
TLS3_k127_5814804_2	760192.Halhy_2377	3.115e-118	396.0	COG1228@1|root,COG1228@2|Bacteria,4NHGA@976|Bacteroidetes,1IWA0@117747|Sphingobacteriia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
TLS3_k127_5814804_0	1237149.C900_01585	2.031e-204	646.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,47JC0@768503|Cytophagia	976|Bacteroidetes	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_5814804_1	1237149.C900_01584	4.203e-175	561.0	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,47M6X@768503|Cytophagia	976|Bacteroidetes	Q	PFAM Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
TLS3_k127_5814804_8	1237149.C900_02388	2.802e-30	127.0	COG5340@1|root,COG5340@2|Bacteria,4NM5Y@976|Bacteroidetes,47V3H@768503|Cytophagia	976|Bacteroidetes	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5814804_5	1237149.C900_02387	8.366e-99	329.0	COG2253@1|root,COG2253@2|Bacteria,4NHEP@976|Bacteroidetes,47TCY@768503|Cytophagia	976|Bacteroidetes	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
TLS3_k127_5814804_6	1237149.C900_00768	3.046e-74	257.0	COG3279@1|root,COG3279@2|Bacteria,4NNUY@976|Bacteroidetes	976|Bacteroidetes	K	COGs COG3279 Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_5814804_4	1237149.C900_00769	7.786e-110	366.0	COG2972@1|root,COG2972@2|Bacteria,4NMUF@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_5820131_0	1121405.dsmv_3003	0.0	1051.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	glycosyltransferase 36 associated	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
TLS3_k127_5820131_2	700598.Niako_5826	9.614e-22	98.0	COG0745@1|root,COG0745@2|Bacteria	700598.Niako_5826|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5820131_1	869213.JCM21142_93455	3.227e-180	571.0	COG0027@1|root,COG0027@2|Bacteria,4PKAW@976|Bacteroidetes	976|Bacteroidetes	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,Epimerase
TLS3_k127_5820990_0	1237149.C900_05467	2.552e-168	533.0	COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,47KC8@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
TLS3_k127_5820990_1	1237149.C900_01348	1.951e-145	470.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,47KG8@768503|Cytophagia	976|Bacteroidetes	H	MoeZ MoeB domain	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
TLS3_k127_5822859_4	313606.M23134_08315	4.13e-13	78.0	2EKDG@1|root,33E3S@2|Bacteria,4NY5W@976|Bacteroidetes,47VUR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5822859_2	313606.M23134_08314	1.871e-62	220.0	COG1595@1|root,COG1595@2|Bacteria,4NU4K@976|Bacteroidetes,47UQA@768503|Cytophagia	976|Bacteroidetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_5822859_1	643867.Ftrac_3122	5.233e-118	384.0	COG0500@1|root,COG2226@2|Bacteria,4NE6P@976|Bacteroidetes,47K6K@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	rebM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_5822859_0	1124780.ANNU01000037_gene135	1.766e-173	548.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,47MD1@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
TLS3_k127_5822859_3	471854.Dfer_5217	5.003e-52	193.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,47M2U@768503|Cytophagia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
TLS3_k127_5854047_1	1048983.EL17_08490	5.305e-115	374.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,47JIN@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
TLS3_k127_5854047_0	1237149.C900_01581	2.929e-115	377.0	COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,47MT6@768503|Cytophagia	976|Bacteroidetes	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TLS3_k127_5854047_2	163908.KB235896_gene4139	9.277e-06	57.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1HK1F@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
TLS3_k127_5857683_1	1380600.AUYN01000006_gene442	4.079e-48	174.0	COG0492@1|root,COG0492@2|Bacteria,4NJFI@976|Bacteroidetes	976|Bacteroidetes	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
TLS3_k127_5857683_2	1443665.JACA01000034_gene2488	5.088e-37	154.0	COG0477@1|root,COG2814@2|Bacteria,4NS0U@976|Bacteroidetes,1I8C9@117743|Flavobacteriia,2YJ73@290174|Aquimarina	976|Bacteroidetes	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_5857683_0	1123248.KB893340_gene2683	3.376e-53	193.0	COG1595@1|root,COG1595@2|Bacteria,4NU6U@976|Bacteroidetes,1J0AR@117747|Sphingobacteriia	976|Bacteroidetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_5857683_3	153721.MYP_1302	2.865e-28	121.0	COG2856@1|root,COG2856@2|Bacteria,4PKA4@976|Bacteroidetes,47S6I@768503|Cytophagia	976|Bacteroidetes	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5895833_1	1270193.JARP01000001_gene2263	1.104e-52	194.0	COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,1I2Z5@117743|Flavobacteriia,2NVZ5@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_5895833_0	1270193.JARP01000001_gene2273	5.545e-121	398.0	COG2114@1|root,COG2114@2|Bacteria,4NG5A@976|Bacteroidetes,1HYY0@117743|Flavobacteriia,2NX4T@237|Flavobacterium	976|Bacteroidetes	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
TLS3_k127_5895833_3	251221.35211204	0.0005206	47.0	COG1372@1|root,COG3391@1|root,COG1372@2|Bacteria,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria	1117|Cyanobacteria	DZ	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
TLS3_k127_5905064_0	1237149.C900_02412	1.153e-295	915.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,47MMN@768503|Cytophagia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
TLS3_k127_5905064_2	1237149.C900_04324	6.5e-52	190.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
TLS3_k127_5905064_5	1338011.BD94_2765	7.765e-05	49.0	2DXDI@1|root,344JJ@2|Bacteria,4P596@976|Bacteroidetes	976|Bacteroidetes	S	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
TLS3_k127_5905064_3	1123278.KB893556_gene3806	1.947e-21	95.0	COG2608@1|root,COG2608@2|Bacteria,4NURN@976|Bacteroidetes,47RXV@768503|Cytophagia	976|Bacteroidetes	P	PFAM Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
TLS3_k127_5905064_4	866536.Belba_1288	1.304e-14	79.0	2BV1I@1|root,32QE9@2|Bacteria,4PC1S@976|Bacteroidetes,47WPH@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5905064_1	1166018.FAES_pFAES01102	1.902e-139	444.0	COG3696@1|root,COG3696@2|Bacteria,4NFD2@976|Bacteroidetes,47M26@768503|Cytophagia	976|Bacteroidetes	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS3_k127_5912468_1	1121904.ARBP01000008_gene3243	1.267e-180	576.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47NQI@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_5912468_2	1121904.ARBP01000008_gene3242	3.464e-162	527.0	COG0702@1|root,COG0702@2|Bacteria,4NMR1@976|Bacteroidetes,47JQK@768503|Cytophagia	976|Bacteroidetes	GM	Pfam:SusD	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_3,SusD_RagB
TLS3_k127_5912468_3	755731.Clo1100_2567	1.481e-59	219.0	COG2755@1|root,COG2755@2|Bacteria,1UM7Z@1239|Firmicutes,25GBF@186801|Clostridia,36VJF@31979|Clostridiaceae	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Lipase_GDSL_2
TLS3_k127_5912468_0	926549.KI421517_gene700	5.903e-295	940.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47JJ5@768503|Cytophagia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
TLS3_k127_5915019_1	1237149.C900_02079	1.402e-84	284.0	COG2197@1|root,COG2197@2|Bacteria,4NJW3@976|Bacteroidetes,47NG7@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_5915019_0	1121904.ARBP01000001_gene5586	1.897e-285	897.0	COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_591653_4	755732.Fluta_0029	5.386e-11	65.0	COG2363@1|root,COG2363@2|Bacteria,4NS8F@976|Bacteroidetes,1I3ZS@117743|Flavobacteriia,2PB7J@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
TLS3_k127_591653_6	1392489.JPOL01000002_gene1728	1.201e-08	57.0	COG2363@1|root,COG2363@2|Bacteria,4NS8F@976|Bacteroidetes,1I3ZS@117743|Flavobacteriia,2XJM4@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Protein of unknown function (DUF423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
TLS3_k127_591653_2	755732.Fluta_3154	1.046e-87	304.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1HWXT@117743|Flavobacteriia,2PAVE@246874|Cryomorphaceae	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_591653_3	153721.MYP_81	2.497e-70	244.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,47KTY@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
TLS3_k127_591653_0	755732.Fluta_3150	1.36e-117	389.0	COG1472@1|root,COG1472@2|Bacteria,4NKTT@976|Bacteroidetes,1I1IY@117743|Flavobacteriia,2PBEQ@246874|Cryomorphaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_3
TLS3_k127_591653_1	1218108.KB908291_gene997	1.164e-110	366.0	COG3677@1|root,COG3677@2|Bacteria,4NJC5@976|Bacteroidetes,1I0Y5@117743|Flavobacteriia	976|Bacteroidetes	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
TLS3_k127_5923605_2	1237149.C900_02765	4.935e-82	279.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,47N34@768503|Cytophagia	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
TLS3_k127_5923605_3	1237149.C900_02763	1.799e-75	261.0	COG0428@1|root,COG0428@2|Bacteria,4NG1R@976|Bacteroidetes,47Q1F@768503|Cytophagia	976|Bacteroidetes	P	ZIP Zinc transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
TLS3_k127_5923605_1	700598.Niako_4337	4.025e-93	316.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	pqqC	-	1.3.3.11	ko:K06137,ko:K06138	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,PqqD,Radical_SAM,SPASM,TENA_THI-4
TLS3_k127_5923605_4	1237149.C900_04428	1.05e-40	153.0	COG1695@1|root,COG1695@2|Bacteria,4P48E@976|Bacteroidetes,47V9J@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_5923605_0	929556.Solca_0257	3.83e-156	515.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IQ8S@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_5929611_3	1237149.C900_03505	1.875e-75	261.0	COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,47N4G@768503|Cytophagia	976|Bacteroidetes	H	PFAM Tetrapyrrole (Corrin Porphyrin) Methylases	rsmI_1	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
TLS3_k127_5929611_5	338966.Ppro_1650	4.262e-18	85.0	COG3071@1|root,COG3071@2|Bacteria,1N6Y8@1224|Proteobacteria,42WU5@68525|delta/epsilon subdivisions,2WRRS@28221|Deltaproteobacteria,43SRB@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
TLS3_k127_5929611_0	1237149.C900_03194	2.85e-150	484.0	COG0520@1|root,COG0520@2|Bacteria,4NJEQ@976|Bacteroidetes,47NQ3@768503|Cytophagia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
TLS3_k127_5929611_2	1123248.KB893348_gene343	3.932e-93	315.0	COG0697@1|root,COG0697@2|Bacteria,4NGPQ@976|Bacteroidetes,1IXG8@117747|Sphingobacteriia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_5929611_4	1237149.C900_03196	3.249e-57	206.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
TLS3_k127_5929611_1	1123057.P872_04615	5.79e-95	314.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,47P9Q@768503|Cytophagia	976|Bacteroidetes	F	deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
TLS3_k127_5929611_6	1237149.C900_03945	5.384e-06	49.0	COG4538@1|root,COG4538@2|Bacteria,4PKKQ@976|Bacteroidetes	976|Bacteroidetes	E	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,SnoaL_2
TLS3_k127_5935981_0	1237149.C900_00608	0.0	1163.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47JN3@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_5935981_2	1237149.C900_00607	1.374e-92	315.0	2DN4I@1|root,32VGS@2|Bacteria,4NNY4@976|Bacteroidetes,47RGS@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
TLS3_k127_5935981_1	1237149.C900_00597	4.163e-301	947.0	COG0823@1|root,COG0823@2|Bacteria,4NGPR@976|Bacteroidetes,47MQP@768503|Cytophagia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5946792_3	471870.BACINT_03009	2.618e-05	48.0	2AD4H@1|root,312T0@2|Bacteria,4PHR9@976|Bacteroidetes,2FR0A@200643|Bacteroidia,4AM05@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5946792_2	471870.BACINT_03010	5.012e-39	154.0	29XIK@1|root,30J9I@2|Bacteria,4PJFA@976|Bacteroidetes,2FQ1Z@200643|Bacteroidia,4APPZ@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
TLS3_k127_5946792_1	471870.BACINT_02994	1.385e-113	383.0	COG0446@1|root,COG0446@2|Bacteria,4PN4M@976|Bacteroidetes,2G0Q4@200643|Bacteroidia,4AVBV@815|Bacteroidaceae	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_5946792_0	742727.HMPREF9447_03849	1.113e-217	696.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FW53@200643|Bacteroidia,4AKCT@815|Bacteroidaceae	976|Bacteroidetes	P	COG NOG06407 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_5951537_1	1237149.C900_04591	2.934e-94	314.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,47MA3@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5951537_0	1237149.C900_04592	2.949e-116	392.0	28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,47JTS@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
TLS3_k127_5951537_2	1237149.C900_04593	2.207e-81	283.0	2C97B@1|root,2ZAEJ@2|Bacteria,4NEK0@976|Bacteroidetes,47MC2@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM gliding motility associated protien GldN	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5960511_0	1048983.EL17_05790	3.5e-247	768.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,47JFM@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
TLS3_k127_5960511_8	1237149.C900_03869	2.807e-57	205.0	COG0224@1|root,COG0224@2|Bacteria,4NM5H@976|Bacteroidetes,47Q4T@768503|Cytophagia	976|Bacteroidetes	C	PFAM WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
TLS3_k127_5960511_6	1124780.ANNU01000035_gene282	1.185e-88	298.0	COG0009@1|root,COG0009@2|Bacteria,4NDZR@976|Bacteroidetes,47KWK@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
TLS3_k127_5960511_2	1237149.C900_03871	2.713e-139	451.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,47J93@768503|Cytophagia	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
TLS3_k127_5960511_9	1237149.C900_03872	2.037e-53	190.0	COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,47Q99@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
TLS3_k127_5960511_4	1237149.C900_03873	1.379e-109	363.0	COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes,47KA8@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM YihY family protein (not ribonuclease BN)	yfkH	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
TLS3_k127_5960511_10	1237149.C900_03174	2.936e-33	134.0	COG5608@1|root,COG5608@2|Bacteria,4NVQ5@976|Bacteroidetes	976|Bacteroidetes	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
TLS3_k127_5960511_7	1124780.ANNU01000043_gene339	2.961e-68	237.0	COG3751@1|root,COG3751@2|Bacteria,4NFPS@976|Bacteroidetes,47MBX@768503|Cytophagia	976|Bacteroidetes	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3,2OG-FeII_Oxy_4
TLS3_k127_5960511_11	1237149.C900_00817	1.925e-32	132.0	COG2318@1|root,COG2318@2|Bacteria,4NSE5@976|Bacteroidetes,47S2U@768503|Cytophagia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
TLS3_k127_5960511_5	929562.Emtol_1880	3.813e-91	307.0	COG0412@1|root,COG0412@2|Bacteria,4NE8V@976|Bacteroidetes,47KK1@768503|Cytophagia	976|Bacteroidetes	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
TLS3_k127_5960511_1	1484460.JSWG01000011_gene1711	1.746e-190	609.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1I7ZI@117743|Flavobacteriia	976|Bacteroidetes	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
TLS3_k127_5960511_3	1279009.ADICEAN_03706	9.934e-114	372.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,47KYI@768503|Cytophagia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
TLS3_k127_5966802_1	1220534.B655_2409	1.791e-29	138.0	arCOG02352@1|root,arCOG05183@1|root,arCOG02352@2157|Archaea,arCOG05183@2157|Archaea	2157|Archaea	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,PAS,PAS_4,PAS_8,PAS_9,PocR,Response_reg
TLS3_k127_5966802_0	1408473.JHXO01000007_gene767	4.696e-60	237.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,4NR59@976|Bacteroidetes,2FWXC@200643|Bacteroidia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_5979160_2	1185876.BN8_00670	7.71e-50	185.0	COG0664@1|root,COG0664@2|Bacteria,4NQQP@976|Bacteroidetes,47R70@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
TLS3_k127_5979160_0	471854.Dfer_5310	4.913e-293	919.0	COG4774@1|root,COG4774@2|Bacteria,4PKNF@976|Bacteroidetes,47XXH@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
TLS3_k127_5979160_1	1123277.KB893195_gene5747	8.184e-55	194.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,47K7Q@768503|Cytophagia	976|Bacteroidetes	G	Major Facilitator Superfamily	fucP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
TLS3_k127_5979922_2	1511.CLOST_1626	2.999e-48	177.0	COG0346@1|root,COG0346@2|Bacteria,1V4NM@1239|Firmicutes,24HFS@186801|Clostridia,25U2S@186804|Peptostreptococcaceae	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
TLS3_k127_5979922_5	1123248.KB893322_gene598	5.21e-23	104.0	COG2318@1|root,COG2318@2|Bacteria,4NPSF@976|Bacteroidetes	976|Bacteroidetes	S	Pfam DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
TLS3_k127_5979922_1	1173023.KE650771_gene1475	3.453e-67	236.0	COG3467@1|root,COG3467@2|Bacteria,1G4RC@1117|Cyanobacteria,1JJWX@1189|Stigonemataceae	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
TLS3_k127_5979922_4	1121929.KB898675_gene2202	1.16e-39	152.0	COG0454@1|root,COG0456@2|Bacteria,1UI3A@1239|Firmicutes,4ISBV@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
TLS3_k127_5979922_0	1519464.HY22_00050	9.107e-101	340.0	COG0604@1|root,COG0604@2|Bacteria	2|Bacteria	C	NADPH:quinone reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_5979922_3	700598.Niako_5818	7.011e-41	154.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1IP2X@117747|Sphingobacteriia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_602349_0	1237149.C900_00494	1.221e-102	344.0	COG4206@1|root,COG4206@2|Bacteria,4PKCR@976|Bacteroidetes,47Y24@768503|Cytophagia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_602349_1	1121904.ARBP01000037_gene2030	4.855e-94	323.0	COG0457@1|root,COG0457@2|Bacteria,4NIUI@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_19,TPR_8
TLS3_k127_602349_3	700598.Niako_2048	4.161e-61	215.0	28IYJ@1|root,2Z8W9@2|Bacteria,4NJ8H@976|Bacteroidetes,1IXX5@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
TLS3_k127_602349_2	745718.JADT01000001_gene2111	3.187e-71	247.0	29ZMS@1|root,30MNA@2|Bacteria,4NGT7@976|Bacteroidetes,1HZ2K@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
TLS3_k127_602349_4	643867.Ftrac_3318	1.112e-55	203.0	COG1595@1|root,COG1595@2|Bacteria,4NMIY@976|Bacteroidetes,47QEF@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS3_k127_602349_5	1286632.P278_16530	9.026e-06	49.0	COG5343@1|root,COG5343@2|Bacteria,4NI2H@976|Bacteroidetes,1HXK4@117743|Flavobacteriia	976|Bacteroidetes	S	Anti-sigma-K factor RskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
TLS3_k127_602400_0	1237149.C900_02668	0.0	1092.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,47KK6@768503|Cytophagia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
TLS3_k127_602400_1	1121859.KB890759_gene1929	1.362e-39	157.0	COG2234@1|root,COG2234@2|Bacteria,4NEHY@976|Bacteroidetes,47NK2@768503|Cytophagia	976|Bacteroidetes	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
TLS3_k127_6025319_2	1237149.C900_02657	1.683e-48	176.0	COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes,47R5X@768503|Cytophagia	976|Bacteroidetes	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6025319_0	1237149.C900_02654	6.005e-259	808.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,47TV8@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
TLS3_k127_6032412_1	880526.KE386488_gene786	1.502e-164	534.0	COG3525@1|root,COG3525@2|Bacteria,4NEQN@976|Bacteroidetes,2FMUE@200643|Bacteroidia,22V00@171550|Rikenellaceae	976|Bacteroidetes	G	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
TLS3_k127_6032412_2	504472.Slin_2036	5.644e-154	496.0	COG4299@1|root,COG4299@2|Bacteria,4NIQV@976|Bacteroidetes,47K6H@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
TLS3_k127_6032412_7	1121481.AUAS01000006_gene832	7.785e-85	291.0	COG3325@1|root,COG3325@2|Bacteria,4NNUM@976|Bacteroidetes,47PUW@768503|Cytophagia	976|Bacteroidetes	G	Glycoside hydrolase family	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
TLS3_k127_6032412_0	1237149.C900_00331	3.249e-225	705.0	COG1488@1|root,COG1488@2|Bacteria,4NFQK@976|Bacteroidetes,47MZ6@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
TLS3_k127_6032412_6	1237149.C900_00330	3.067e-95	315.0	COG1335@1|root,COG1335@2|Bacteria,4NKPP@976|Bacteroidetes,47PIR@768503|Cytophagia	976|Bacteroidetes	Q	Isochorismatase family	pncA	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
TLS3_k127_6032412_4	1123278.KB893533_gene139	8.54e-113	372.0	COG0449@1|root,COG0449@2|Bacteria,4NK32@976|Bacteroidetes,47M7K@768503|Cytophagia	976|Bacteroidetes	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	-
TLS3_k127_6032412_5	1123278.KB893533_gene141	1.144e-105	351.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,47MWX@768503|Cytophagia	976|Bacteroidetes	G	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
TLS3_k127_6032412_3	761193.Runsl_4764	6.856e-152	486.0	COG1063@1|root,COG1063@2|Bacteria,4NHCK@976|Bacteroidetes,47K5V@768503|Cytophagia	976|Bacteroidetes	E	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_6032412_8	1121373.KB903639_gene3777	2.445e-35	141.0	2EE1E@1|root,337W8@2|Bacteria,4NVDI@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6064690_2	1237149.C900_04444	1.554e-184	584.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47KGA@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	amaA	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_6064690_1	760192.Halhy_6230	2.691e-198	636.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NEJ0@976|Bacteroidetes,1IS7J@117747|Sphingobacteriia	976|Bacteroidetes	CG	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,PA14
TLS3_k127_6064690_0	760192.Halhy_6229	2.946e-282	877.0	COG2133@1|root,COG4654@1|root,COG2133@2|Bacteria,COG4654@2|Bacteria,4NEMM@976|Bacteroidetes,1IR5I@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
TLS3_k127_6067377_2	266748.HY04_14060	1.177e-84	289.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,1HYT4@117743|Flavobacteriia,3ZUKE@59732|Chryseobacterium	976|Bacteroidetes	L	ATP dependent DNA ligase C terminal region	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
TLS3_k127_6067377_0	471854.Dfer_5355	9.437e-161	514.0	COG2982@1|root,COG2982@2|Bacteria,4NIE2@976|Bacteroidetes,47M87@768503|Cytophagia	976|Bacteroidetes	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
TLS3_k127_6067377_3	1124780.ANNU01000005_gene2347	6.349e-48	178.0	COG4119@1|root,COG4119@2|Bacteria,4NRRR@976|Bacteroidetes,47VVR@768503|Cytophagia	976|Bacteroidetes	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_6067377_4	1122621.ATZA01000013_gene3321	6.051e-16	79.0	2EIK5@1|root,33CBF@2|Bacteria,4NV2P@976|Bacteroidetes,1IU6J@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6067377_1	1233951.IO90_06450	2.049e-113	370.0	COG1028@1|root,COG1028@2|Bacteria,4NFK6@976|Bacteroidetes,1HY5Q@117743|Flavobacteriia,3HH5I@358033|Chryseobacterium	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_6080041_0	1237149.C900_05123	3.124e-81	276.0	28KKN@1|root,2ZA5E@2|Bacteria,4NMKH@976|Bacteroidetes,47PT5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6080041_1	1237149.C900_05122	4.642e-29	119.0	COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,47SC6@768503|Cytophagia	976|Bacteroidetes	U	PFAM Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
TLS3_k127_6080041_2	1237149.C900_05121	7.126e-26	119.0	2ECXC@1|root,336UI@2|Bacteria,4NV8T@976|Bacteroidetes,47RWP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6081260_2	376686.Fjoh_3400	6.373e-44	161.0	COG0745@1|root,COG0745@2|Bacteria,4NHXA@976|Bacteroidetes,1HZWH@117743|Flavobacteriia,2NSGF@237|Flavobacterium	976|Bacteroidetes	T	Transcriptional regulator	cusR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_6081260_0	925409.KI911562_gene1331	8.005e-97	319.0	COG0262@1|root,COG0262@2|Bacteria,4NPM3@976|Bacteroidetes,1IT7M@117747|Sphingobacteriia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
TLS3_k127_6081260_1	1237149.C900_00554	3.706e-48	178.0	2CB8S@1|root,30PE6@2|Bacteria,4NU1E@976|Bacteroidetes,47RMQ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
TLS3_k127_6081260_3	1237149.C900_00555	3.059e-37	144.0	COG2197@1|root,COG2197@2|Bacteria,4NQSY@976|Bacteroidetes,47QHW@768503|Cytophagia	976|Bacteroidetes	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
TLS3_k127_6085714_4	1004149.AFOE01000059_gene376	3.744e-35	141.0	COG0115@1|root,COG0115@2|Bacteria,4NSFJ@976|Bacteroidetes,1I3H2@117743|Flavobacteriia	976|Bacteroidetes	EH	aminodeoxychorismate lyase	-	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
TLS3_k127_6085714_2	1408473.JHXO01000008_gene2778	1.172e-107	357.0	COG0147@1|root,COG0147@2|Bacteria,4NFKB@976|Bacteroidetes,2FMRN@200643|Bacteroidia	976|Bacteroidetes	EH	para-aminobenzoate synthase component I	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Chorismate_bind
TLS3_k127_6085714_3	1150600.ADIARSV_1390	3.769e-91	303.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1IQ8P@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
TLS3_k127_6085714_1	1237149.C900_04961	4.038e-112	369.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,47K0S@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
TLS3_k127_6085714_0	1237149.C900_04963	2.794e-293	906.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,47K4P@768503|Cytophagia	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
TLS3_k127_6116550_1	468059.AUHA01000004_gene2103	6.134e-101	339.0	COG0168@1|root,COG0168@2|Bacteria,4NF7R@976|Bacteroidetes,1IREE@117747|Sphingobacteriia	976|Bacteroidetes	P	Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
TLS3_k127_6116550_2	1346330.M472_22140	3.628e-54	198.0	COG0569@1|root,COG0569@2|Bacteria,4NGRQ@976|Bacteroidetes,1IPNR@117747|Sphingobacteriia	976|Bacteroidetes	P	TrkA-N domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
TLS3_k127_6116550_0	761193.Runsl_0495	4.359e-262	816.0	COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes,47MY3@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
TLS3_k127_612007_4	1122605.KB893645_gene966	7.326e-23	100.0	COG0329@1|root,COG0329@2|Bacteria,4NFCZ@976|Bacteroidetes,1IR3S@117747|Sphingobacteriia	976|Bacteroidetes	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
TLS3_k127_612007_3	383372.Rcas_3215	6.163e-89	303.0	COG0673@1|root,COG0673@2|Bacteria,2G7R0@200795|Chloroflexi,377Y3@32061|Chloroflexia	32061|Chloroflexia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_612007_2	1121011.AUCB01000006_gene1012	3.98e-220	699.0	COG1409@1|root,COG1409@2|Bacteria,4PIW1@976|Bacteroidetes,1INKP@117743|Flavobacteriia,23IE7@178469|Arenibacter	976|Bacteroidetes	S	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
TLS3_k127_612007_0	504472.Slin_6608	2.026e-319	994.0	COG3292@1|root,COG3292@2|Bacteria,4NF9I@976|Bacteroidetes,47MWU@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
TLS3_k127_612007_1	1121904.ARBP01000043_gene2123	1.283e-242	766.0	COG3292@1|root,COG3292@2|Bacteria,4NE4U@976|Bacteroidetes,47JHS@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6122833_1	525257.HMPREF0204_13119	3.129e-228	716.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1HYU9@117743|Flavobacteriia,3ZTEE@59732|Chryseobacterium	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_6122833_2	504472.Slin_0945	2.824e-36	140.0	COG1695@1|root,COG1695@2|Bacteria,4NS5H@976|Bacteroidetes,47QMA@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_6122833_0	504472.Slin_3637	9.29e-303	951.0	COG0577@1|root,COG0577@2|Bacteria,4P1B0@976|Bacteroidetes,47U89@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	MacB_PCD
TLS3_k127_6125748_1	1237149.C900_04596	2.538e-220	705.0	COG0457@1|root,COG0457@2|Bacteria,4NDV9@976|Bacteroidetes,47K0V@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeats	sprE	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
TLS3_k127_6125748_6	643867.Ftrac_2563	1.129e-93	315.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,47PPP@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_6125748_8	1237149.C900_04598	1.09e-52	189.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,47RT9@768503|Cytophagia	976|Bacteroidetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
TLS3_k127_6125748_13	1124780.ANNU01000006_gene2929	6.437e-07	54.0	2DQFZ@1|root,336KY@2|Bacteria,4NVIZ@976|Bacteroidetes,47SK8@768503|Cytophagia	976|Bacteroidetes	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
TLS3_k127_6125748_5	1121859.KB890738_gene2968	5.757e-106	353.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,47JYV@768503|Cytophagia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
TLS3_k127_6125748_10	388413.ALPR1_20523	6.779e-23	100.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,47S5V@768503|Cytophagia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
TLS3_k127_6125748_9	926556.Echvi_0610	1.492e-44	166.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,47Q9K@768503|Cytophagia	976|Bacteroidetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
TLS3_k127_6125748_7	1237149.C900_04604	4.748e-69	238.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,47QGS@768503|Cytophagia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
TLS3_k127_6125748_0	1237149.C900_04605	6.921e-285	880.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,47JFI@768503|Cytophagia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
TLS3_k127_6125748_4	1237149.C900_04606	1.343e-110	364.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,47JM0@768503|Cytophagia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
TLS3_k127_6125748_11	1237149.C900_04074	8.779e-19	90.0	COG3093@1|root,COG3093@2|Bacteria,4PC9U@976|Bacteroidetes,47X26@768503|Cytophagia	976|Bacteroidetes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
TLS3_k127_6125748_12	1499967.BAYZ01000005_gene5453	2.126e-12	73.0	2DTZ2@1|root,33N9Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6125748_3	1237149.C900_00364	1.407e-142	473.0	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,4NM7H@976|Bacteroidetes,47XEC@768503|Cytophagia	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
TLS3_k127_6125748_2	1237149.C900_00365	1.152e-166	531.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,47M7W@768503|Cytophagia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6135671_0	1123248.KB893337_gene2378	1.793e-117	385.0	COG1082@1|root,COG1082@2|Bacteria,4NJJZ@976|Bacteroidetes,1IQTR@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Xylose	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_6135671_3	313606.M23134_05445	4.936e-24	102.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes,47U0W@768503|Cytophagia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
TLS3_k127_6135671_1	1453498.LG45_09075	1.185e-81	285.0	COG0642@1|root,COG2199@1|root,COG2199@2|Bacteria,COG2205@2|Bacteria,4P15P@976|Bacteroidetes,1IK2K@117743|Flavobacteriia,2P0U3@237|Flavobacterium	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_6135671_2	1122621.ATZA01000005_gene580	5.772e-77	265.0	COG0823@1|root,COG0823@2|Bacteria,4NFRP@976|Bacteroidetes,1IPPY@117747|Sphingobacteriia	976|Bacteroidetes	U	Protein of unknown function (DUF3748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3748,PD40
TLS3_k127_6138085_3	1250005.PHEL85_0743	6.744e-43	160.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,1HX94@117743|Flavobacteriia,3VVSS@52959|Polaribacter	976|Bacteroidetes	S	Eukaryotic integral membrane protein (DUF1751)	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
TLS3_k127_6138085_0	153721.MYP_3854	1.13e-108	362.0	COG2935@1|root,COG2935@2|Bacteria,4NGKN@976|Bacteroidetes,47PCC@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the R-transferase family	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
TLS3_k127_6138085_1	1237149.C900_04562	1.189e-86	297.0	COG3250@1|root,COG3250@2|Bacteria,4NN59@976|Bacteroidetes	976|Bacteroidetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BetaGal_dom4_5
TLS3_k127_6138085_2	945713.IALB_2692	7.198e-83	284.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	BetaGal_dom4_5,F5_F8_type_C
TLS3_k127_6143055_0	714943.Mucpa_4628	5.266e-158	511.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1IPF5@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
TLS3_k127_6143055_2	1487953.JMKF01000035_gene1150	1.276e-22	100.0	COG4122@1|root,COG4122@2|Bacteria,1GA7Q@1117|Cyanobacteria,1HDHZ@1150|Oscillatoriales	1117|Cyanobacteria	S	Macrocin-O-methyltransferase (TylF)	-	-	-	ko:K05303	-	-	-	-	ko00000,ko01000	-	-	-	TylF
TLS3_k127_6143055_1	700598.Niako_2669	5.501e-36	143.0	COG1595@1|root,COG1595@2|Bacteria,4NSXH@976|Bacteroidetes,1ITK2@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM RNA polymerase sigma factor 70, region 4 type 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_6143055_3	760192.Halhy_4820	7.57e-19	93.0	COG3712@1|root,COG3712@2|Bacteria,4NPYZ@976|Bacteroidetes,1IVEP@117747|Sphingobacteriia	976|Bacteroidetes	PT	COG3712 Fe2 -dicitrate sensor, membrane component	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
TLS3_k127_615034_1	1237149.C900_02550	1.023e-251	790.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
TLS3_k127_615034_0	643867.Ftrac_0818	9.486e-276	862.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,47KR4@768503|Cytophagia	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
TLS3_k127_615034_4	1237149.C900_02552	3.435e-43	163.0	2ENX1@1|root,33GHZ@2|Bacteria,4NXFU@976|Bacteroidetes,47WQI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_615034_3	1237149.C900_02553	7.546e-106	350.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,47MC7@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
TLS3_k127_615034_5	1454007.JAUG01000061_gene473	4.916e-22	96.0	2BVK8@1|root,32Y0S@2|Bacteria,4NUUA@976|Bacteroidetes,1ITXR@117747|Sphingobacteriia	976|Bacteroidetes	S	histone H1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hc1
TLS3_k127_615034_2	1237149.C900_04344	9.768e-217	678.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,47KDV@768503|Cytophagia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_615034_6	1048983.EL17_17380	1.436e-16	80.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,47M7U@768503|Cytophagia	976|Bacteroidetes	I	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
TLS3_k127_6158936_10	1237149.C900_05843	4.444e-11	65.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,47QIE@768503|Cytophagia	976|Bacteroidetes	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TLS3_k127_6158936_9	1232410.KI421424_gene1627	2.604e-21	98.0	COG0745@1|root,COG0745@2|Bacteria,1NZI7@1224|Proteobacteria,430PP@68525|delta/epsilon subdivisions,2WVYC@28221|Deltaproteobacteria,43V84@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_6158936_1	1122605.KB893644_gene1308	1.073e-217	683.0	COG0673@1|root,COG0673@2|Bacteria,4NF9M@976|Bacteroidetes,1IPWB@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
TLS3_k127_6158936_5	700598.Niako_6919	3.545e-120	393.0	COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes,1IS6V@117747|Sphingobacteriia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,FGE-sulfatase
TLS3_k127_6158936_3	1120965.AUBV01000003_gene444	1.47e-147	477.0	COG0144@1|root,COG0144@2|Bacteria,4NEV7@976|Bacteroidetes,47NAK@768503|Cytophagia	976|Bacteroidetes	J	TIGRFAM ribosomal RNA small subunit methyltransferase RsmB	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
TLS3_k127_6158936_4	1121904.ARBP01000006_gene3817	6.567e-142	456.0	COG3622@1|root,COG3622@2|Bacteria,4NG74@976|Bacteroidetes,47K7Z@768503|Cytophagia	976|Bacteroidetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
TLS3_k127_6158936_0	1237149.C900_05842	5.099e-300	948.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,47NIF@768503|Cytophagia	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_8
TLS3_k127_6158936_2	926549.KI421517_gene3457	9.048e-153	488.0	COG0667@1|root,COG0667@2|Bacteria,4NF06@976|Bacteroidetes,47K7K@768503|Cytophagia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_6158936_8	118161.KB235922_gene4391	9.131e-46	170.0	COG1611@1|root,COG1611@2|Bacteria,1G5P3@1117|Cyanobacteria,3VK1P@52604|Pleurocapsales	1117|Cyanobacteria	S	TIGRFAM TIGR00725 family protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
TLS3_k127_6158936_12	1323663.AROI01000009_gene3557	6.128e-05	51.0	2APBA@1|root,31EDH@2|Bacteria,1RIDJ@1224|Proteobacteria,1S6VZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
TLS3_k127_6158936_7	485918.Cpin_0921	1.103e-54	197.0	COG4502@1|root,COG4502@2|Bacteria,4NQDT@976|Bacteroidetes,1ISVS@117747|Sphingobacteriia	976|Bacteroidetes	S	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	NT5C
TLS3_k127_6158936_6	945713.IALB_2746	9.998e-74	251.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_6158936_11	1123277.KB893173_gene1827	3.748e-05	50.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,47JM8@768503|Cytophagia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3829,VWA,VWA_2
TLS3_k127_6159254_0	1237149.C900_01121	8.481e-231	724.0	COG2885@1|root,COG2885@2|Bacteria,4NHWF@976|Bacteroidetes,47MMG@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
TLS3_k127_6159254_1	1237149.C900_00390	1.509e-92	311.0	COG3595@1|root,COG3595@2|Bacteria,4NGRU@976|Bacteroidetes,47MSM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
TLS3_k127_6159254_2	1237149.C900_00391	2.881e-77	268.0	COG3595@1|root,COG3595@2|Bacteria,4NJBA@976|Bacteroidetes,47MRP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6163428_0	985054.JQEZ01000003_gene1452	1.215e-121	411.0	COG1232@1|root,COG1232@2|Bacteria,1P80H@1224|Proteobacteria,2TU24@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
TLS3_k127_6163428_1	1056495.Calag_0379	4.3e-44	169.0	COG0463@1|root,COG2246@1|root,arCOG00894@2157|Archaea,arCOG02228@2157|Archaea,2XQ9U@28889|Crenarchaeota	28889|Crenarchaeota	M	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
TLS3_k127_6165289_6	929703.KE386491_gene3837	2.72e-05	47.0	COG0531@1|root,COG0531@2|Bacteria,4NJPZ@976|Bacteroidetes,47MX2@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
TLS3_k127_6165289_1	471854.Dfer_5647	6.25e-227	709.0	COG1271@1|root,COG1271@2|Bacteria,4NG7U@976|Bacteroidetes,47N3T@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome bd terminal oxidase subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
TLS3_k127_6165289_2	1270196.JCKI01000008_gene1663	1.757e-146	470.0	COG1294@1|root,COG1294@2|Bacteria,4NH9P@976|Bacteroidetes,1IRPP@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1294 Cytochrome bd-type quinol oxidase subunit 2	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
TLS3_k127_6165289_0	1121904.ARBP01000002_gene7252	7.886e-244	778.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_6165289_4	926549.KI421517_gene4105	7.129e-108	360.0	COG2133@1|root,COG2133@2|Bacteria,4NGMS@976|Bacteroidetes,47KFU@768503|Cytophagia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_6165289_5	1408473.JHXO01000009_gene3299	7.644e-58	213.0	COG3595@1|root,COG3595@2|Bacteria,4NJCC@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
TLS3_k127_6165289_3	509635.N824_07005	4.699e-123	400.0	2BZ6M@1|root,2Z7HW@2|Bacteria,4NDZE@976|Bacteroidetes,1INP8@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_6187915_5	1123057.P872_16635	7.985e-46	166.0	COG0346@1|root,COG0346@2|Bacteria,4NDVG@976|Bacteroidetes,47MTQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
TLS3_k127_6187915_1	1237149.C900_05228	6.928e-105	348.0	COG1196@1|root,COG1196@2|Bacteria,4NHAC@976|Bacteroidetes,47MGD@768503|Cytophagia	976|Bacteroidetes	D	nuclear chromosome segregation	-	-	-	ko:K09892	-	-	-	-	ko00000,ko03036	-	-	-	-
TLS3_k127_6187915_4	313606.M23134_06731	1.514e-62	225.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,47N8Y@768503|Cytophagia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
TLS3_k127_6187915_3	1237149.C900_05945	7.863e-64	221.0	COG2967@1|root,COG2967@2|Bacteria,4NNRA@976|Bacteroidetes,47PP3@768503|Cytophagia	976|Bacteroidetes	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
TLS3_k127_6187915_0	1237149.C900_05944	1.945e-112	367.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,47JRB@768503|Cytophagia	976|Bacteroidetes	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
TLS3_k127_6187915_2	1237149.C900_05943	1.465e-73	254.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,47JH7@768503|Cytophagia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
TLS3_k127_6190673_0	1237149.C900_04413	7.324e-96	317.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,47K5F@768503|Cytophagia	976|Bacteroidetes	Q	PFAM Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_6190673_1	1123276.KB893254_gene3497	3.096e-17	92.0	28Q1T@1|root,2ZCK1@2|Bacteria,4NN1T@976|Bacteroidetes,47PK9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6193210_1	929703.KE386491_gene1729	3.23e-117	387.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_6193210_2	929562.Emtol_0942	4.606e-18	86.0	COG1943@1|root,COG1943@2|Bacteria,4NQTF@976|Bacteroidetes,47Q23@768503|Cytophagia	976|Bacteroidetes	L	transposase IS200-family protein	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
TLS3_k127_6193210_0	1121904.ARBP01000004_gene1108	3.43e-245	784.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_6208370_5	1237149.C900_03792	7.242e-47	173.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,47NWC@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
TLS3_k127_6208370_4	1237149.C900_03791	5.224e-66	227.0	COG2199@1|root,COG3706@2|Bacteria,4PKDN@976|Bacteroidetes,47QRP@768503|Cytophagia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_6208370_0	1237149.C900_03789	5.122e-148	489.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NHG0@976|Bacteroidetes,47JZ1@768503|Cytophagia	976|Bacteroidetes	M	PFAM Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
TLS3_k127_6208370_2	1121859.KB890760_gene1988	6.521e-92	306.0	COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,47KAK@768503|Cytophagia	976|Bacteroidetes	S	PFAM O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
TLS3_k127_6208370_1	1237149.C900_03787	6.444e-142	461.0	COG0612@1|root,COG0612@2|Bacteria,4NEE4@976|Bacteroidetes,47JFQ@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_6208370_3	1237149.C900_03785	2.86e-67	233.0	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,47K9N@768503|Cytophagia	976|Bacteroidetes	F	PFAM Phosphorylase superfamily	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
TLS3_k127_6239994_1	421072.IO89_10490	6.466e-70	242.0	COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,1I18C@117743|Flavobacteriia,3HIQD@358033|Chryseobacterium	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_6239994_2	1122225.AULQ01000004_gene1966	3.72e-39	149.0	2CWCM@1|root,32SZF@2|Bacteria,4NSAZ@976|Bacteroidetes,1I2Z7@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4260)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4260
TLS3_k127_6239994_0	1237149.C900_01149	1.519e-210	664.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia	976|Bacteroidetes	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS3_k127_6242129_1	1120965.AUBV01000012_gene1394	1.114e-23	104.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
TLS3_k127_6242129_0	1317122.ATO12_19400	3.54e-105	349.0	COG2801@1|root,COG2801@2|Bacteria,4NF3Q@976|Bacteroidetes,1HZT4@117743|Flavobacteriia,2YK2V@290174|Aquimarina	976|Bacteroidetes	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
TLS3_k127_6244506_0	586413.CCDL010000001_gene1218	2.015e-84	293.0	COG1680@1|root,COG1680@2|Bacteria,1V3KP@1239|Firmicutes,4IDK5@91061|Bacilli,23KW4@182709|Oceanobacillus	91061|Bacilli	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_6244506_1	153721.MYP_4513	3.333e-24	102.0	COG0664@1|root,COG0664@2|Bacteria,4NJ1H@976|Bacteroidetes,47PVN@768503|Cytophagia	976|Bacteroidetes	T	Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
TLS3_k127_6245414_3	1160707.AJIK01000026_gene1515	4.516e-05	48.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,4HA91@91061|Bacilli,26D5N@186818|Planococcaceae	91061|Bacilli	G	Belongs to the glycerate kinase type-1 family	-	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
TLS3_k127_6245414_0	1237149.C900_04390	6.075e-239	743.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,47MYD@768503|Cytophagia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
TLS3_k127_6245414_1	1237149.C900_04901	4.578e-47	174.0	COG0457@1|root,COG0457@2|Bacteria,4NQR8@976|Bacteroidetes,47YIZ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
TLS3_k127_6245414_2	1237149.C900_04900	1.501e-30	123.0	COG4067@1|root,COG4067@2|Bacteria,4NS86@976|Bacteroidetes,47RH0@768503|Cytophagia	976|Bacteroidetes	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
TLS3_k127_6259964_2	1124780.ANNU01000021_gene3028	2.855e-132	433.0	COG0845@1|root,COG0845@2|Bacteria,4NGSC@976|Bacteroidetes,47TMZ@768503|Cytophagia	976|Bacteroidetes	M	HlyD membrane-fusion protein of T1SS	-	-	-	-	-	-	-	-	-	-	-	-	HlyD,HlyD_3,HlyD_D23
TLS3_k127_6259964_0	1237149.C900_05605	5.422e-185	588.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,47JWH@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_6259964_1	1237149.C900_05606	5.726e-168	541.0	COG1538@1|root,COG1538@2|Bacteria,4NGXM@976|Bacteroidetes,47KVY@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_6259964_3	1492738.FEM21_04080	3.285e-114	380.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,4NFCF@976|Bacteroidetes,1HWJE@117743|Flavobacteriia,2NSE8@237|Flavobacterium	976|Bacteroidetes	P	Transporter	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
TLS3_k127_6261275_2	1237149.C900_03994	9.135e-11	65.0	2A7CX@1|root,334RT@2|Bacteria,4NVQR@976|Bacteroidetes,47RXJ@768503|Cytophagia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_6261275_3	1406840.Q763_13180	3.043e-09	64.0	2AA3V@1|root,30ZCQ@2|Bacteria,4PDJP@976|Bacteroidetes,1IE0X@117743|Flavobacteriia,2NZMC@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6261275_1	1122179.KB890440_gene1010	1.656e-30	131.0	COG4585@1|root,COG4585@2|Bacteria,4NN4R@976|Bacteroidetes,1IXIC@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TLS3_k127_6261275_0	1237149.C900_05519	3.66e-52	191.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,47NAQ@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_626800_0	269798.CHU_3347	8.233e-63	239.0	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,4NE3J@976|Bacteroidetes,47JYY@768503|Cytophagia	976|Bacteroidetes	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
TLS3_k127_626800_1	1237149.C900_01498	4.44e-36	157.0	COG4251@1|root,COG5000@1|root,COG4251@2|Bacteria,COG5000@2|Bacteria,4NDUQ@976|Bacteroidetes,47PTN@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
TLS3_k127_6291220_0	762903.Pedsa_0397	2.625e-114	384.0	COG4452@1|root,COG4452@2|Bacteria,4NGKY@976|Bacteroidetes,1IPKH@117747|Sphingobacteriia	976|Bacteroidetes	V	Inner membrane protein CreD	creD	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
TLS3_k127_6291220_1	1239962.C943_00380	1.369e-80	270.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,47JZ2@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM delta-1-pyrroline-5-carboxylate dehydrogenase, group 1	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
TLS3_k127_6301270_0	1121481.AUAS01000018_gene434	5.993e-82	287.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,47KDN@768503|Cytophagia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS3_k127_6301270_3	929703.KE386491_gene795	1.886e-07	55.0	2DR6N@1|root,33AE8@2|Bacteria	2|Bacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
TLS3_k127_6301270_1	1123276.KB893268_gene4984	4.113e-44	184.0	COG2972@1|root,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,47QDQ@768503|Cytophagia	976|Bacteroidetes	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,His_kinase,TPR_10,TPR_12,TPR_7
TLS3_k127_6306775_3	269798.CHU_3692	4.257e-31	127.0	COG0438@1|root,COG0438@2|Bacteria,4NI16@976|Bacteroidetes,47KFJ@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_6306775_2	929562.Emtol_1110	2.479e-89	298.0	COG2010@1|root,COG2010@2|Bacteria,4PN3J@976|Bacteroidetes,47Y8S@768503|Cytophagia	976|Bacteroidetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_6306775_1	1237149.C900_01514	2.17e-89	299.0	COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,47KW3@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS3_k127_6306775_0	1237149.C900_01516	0.0	1420.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,47JVJ@768503|Cytophagia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
TLS3_k127_6306775_5	762903.Pedsa_0304	1.479e-14	78.0	COG1629@1|root,COG1629@2|Bacteria,4NH4T@976|Bacteroidetes	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_6307747_1	1239962.C943_03737	7.878e-71	243.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47J95@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TLS3_k127_6307747_2	1239962.C943_00989	9.46e-24	109.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	MA20_20735	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_6307747_0	1454007.JAUG01000034_gene3816	1.75e-133	434.0	COG2333@1|root,COG2333@2|Bacteria,4NH12@976|Bacteroidetes,1ISHP@117747|Sphingobacteriia	976|Bacteroidetes	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_631385_3	1406840.Q763_15845	0.0001125	48.0	COG1597@1|root,COG1597@2|Bacteria,4NJ68@976|Bacteroidetes,1HZC0@117743|Flavobacteriia,2NUN4@237|Flavobacterium	976|Bacteroidetes	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_acc,DAGK_cat
TLS3_k127_631385_0	204669.Acid345_4433	1.1e-137	447.0	COG0457@1|root,COG0457@2|Bacteria,3Y4T0@57723|Acidobacteria,2JNAK@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
TLS3_k127_631385_1	1267211.KI669560_gene2830	4.618e-98	344.0	COG0642@1|root,COG2205@2|Bacteria,4P15P@976|Bacteroidetes,1J0GU@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,TPR_12,TPR_8
TLS3_k127_631385_2	1237149.C900_02054	6.497e-45	168.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,47YDB@768503|Cytophagia	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
TLS3_k127_6321084_5	1121904.ARBP01000009_gene4305	2.243e-36	140.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	kdgF	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_6321084_0	1124780.ANNU01000008_gene2665	1.031e-270	841.0	COG2721@1|root,COG2721@2|Bacteria,4NFVQ@976|Bacteroidetes,47K7S@768503|Cytophagia	976|Bacteroidetes	G	PFAM D-galactarate dehydratase Altronate hydrolase	uxaA	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
TLS3_k127_6321084_4	1550091.JROE01000005_gene2029	5.297e-40	157.0	COG0800@1|root,COG0800@2|Bacteria,4NEFY@976|Bacteroidetes,1IS6W@117747|Sphingobacteriia	976|Bacteroidetes	G	KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
TLS3_k127_6321084_1	926549.KI421517_gene716	6.169e-138	446.0	COG0673@1|root,COG0673@2|Bacteria,4NEQB@976|Bacteroidetes,47KWZ@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	yvaA	-	1.1.1.371	ko:K16044	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_6321084_2	1121859.KB890750_gene285	1.059e-126	413.0	COG0524@1|root,COG0524@2|Bacteria,4NFH8@976|Bacteroidetes,47KKJ@768503|Cytophagia	976|Bacteroidetes	G	PFAM PfkB	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
TLS3_k127_6321084_3	926556.Echvi_3630	4.188e-44	165.0	COG0800@1|root,COG0800@2|Bacteria,4NEFY@976|Bacteroidetes,47PM4@768503|Cytophagia	976|Bacteroidetes	G	PFAM KDPG and KHG aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
TLS3_k127_6322443_3	1123057.P872_15705	9.54e-40	149.0	COG1073@1|root,COG1073@2|Bacteria,4NFRN@976|Bacteroidetes,47KAI@768503|Cytophagia	976|Bacteroidetes	E	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
TLS3_k127_6322443_0	1124780.ANNU01000005_gene2415	8.899e-75	257.0	COG0755@1|root,COG0755@2|Bacteria,4NFUS@976|Bacteroidetes,47MYQ@768503|Cytophagia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
TLS3_k127_6322443_5	509635.N824_17785	8.851e-08	56.0	2BZQ6@1|root,339SI@2|Bacteria,4NXJG@976|Bacteroidetes,1IU7C@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6322443_1	1408473.JHXO01000009_gene3254	5.778e-72	246.0	COG0454@1|root,COG0456@2|Bacteria,4NMCW@976|Bacteroidetes	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
TLS3_k127_6322443_2	1123248.KB893385_gene4760	6.721e-57	202.0	2CEUY@1|root,32T7I@2|Bacteria,4PQ0Q@976|Bacteroidetes,1J14D@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_6322443_4	1202532.FF52_22464	2.024e-35	140.0	COG0642@1|root,COG2205@2|Bacteria,4P2BP@976|Bacteroidetes,1IKQ9@117743|Flavobacteriia,2P0TB@237|Flavobacterium	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_633910_2	1121012.AUKX01000010_gene1975	5.188e-93	308.0	COG4409@1|root,COG4409@2|Bacteria,4PKIP@976|Bacteroidetes,1IJA8@117743|Flavobacteriia,23FZ0@178469|Arenibacter	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TLS3_k127_633910_0	1121904.ARBP01000011_gene1450	9.756e-157	501.0	COG1741@1|root,COG1741@2|Bacteria,4NFZD@976|Bacteroidetes,47NGE@768503|Cytophagia	976|Bacteroidetes	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
TLS3_k127_633910_3	1237149.C900_03141	3.875e-44	173.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_633910_1	1237149.C900_03140	8.561e-104	356.0	2ETG7@1|root,33M02@2|Bacteria,4NXSR@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6340764_2	866536.Belba_2228	3.724e-51	183.0	COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,47R38@768503|Cytophagia	976|Bacteroidetes	J	PFAM translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
TLS3_k127_6340764_0	1237149.C900_01591	5.862e-100	332.0	COG3279@1|root,COG3279@2|Bacteria,4NJW4@976|Bacteroidetes	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_6340764_1	1237149.C900_01590	3.215e-89	306.0	COG2972@1|root,COG2972@2|Bacteria,4NPKE@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_6340764_3	1237149.C900_01589	3.04e-50	183.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47N4N@768503|Cytophagia	976|Bacteroidetes	T	PFAM histidine kinase internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_6343457_1	866536.Belba_0547	2.529e-92	304.0	COG3491@1|root,COG3491@2|Bacteria,4NED5@976|Bacteroidetes,47JDX@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
TLS3_k127_6343457_0	1124780.ANNU01000005_gene2393	2.662e-147	477.0	COG2059@1|root,COG2059@2|Bacteria,4NNZ1@976|Bacteroidetes,47JQS@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
TLS3_k127_6343457_2	1237149.C900_04701	9.454e-82	277.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_6343457_3	1237149.C900_01773	7.566e-63	219.0	28MPU@1|root,2ZAYW@2|Bacteria,4NRQD@976|Bacteroidetes,47NJK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6347146_2	1237149.C900_04977	4.084e-35	134.0	COG0251@1|root,COG0251@2|Bacteria,4NMHF@976|Bacteroidetes,47PT2@768503|Cytophagia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	3.5.99.5	ko:K15067	ko00380,map00380	-	R03887	RC01015	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
TLS3_k127_6347146_1	1121957.ATVL01000012_gene650	1.259e-58	213.0	COG5266@1|root,COG5266@2|Bacteria,4NQ8X@976|Bacteroidetes,47QXS@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function (DUF4198)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4198
TLS3_k127_6347146_0	1237149.C900_04979	1.727e-196	620.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,47MAV@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
TLS3_k127_6347146_3	929556.Solca_0474	3.726e-30	127.0	COG2318@1|root,COG2318@2|Bacteria,4NNW4@976|Bacteroidetes,1IT5S@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_6347146_5	1116472.MGMO_73c00110	5.085e-17	85.0	COG3832@1|root,COG3832@2|Bacteria,1RDMX@1224|Proteobacteria,1SFA8@1236|Gammaproteobacteria,1XGCK@135618|Methylococcales	135618|Methylococcales	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_6367007_1	1123400.KB904747_gene458	1.731e-32	135.0	COG0726@1|root,COG0726@2|Bacteria,1NHC2@1224|Proteobacteria	1224|Proteobacteria	G	Protein of unknown function (DUF3298)	yjeA	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
TLS3_k127_6367007_0	1150600.ADIARSV_0626	2.217e-63	224.0	COG1137@1|root,COG1137@2|Bacteria,4NIH5@976|Bacteroidetes,1IT3T@117747|Sphingobacteriia	976|Bacteroidetes	S	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
TLS3_k127_6367007_2	1077285.AGDG01000016_gene561	0.0001815	45.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,2FNCU@200643|Bacteroidia,4AKZ6@815|Bacteroidaceae	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
TLS3_k127_6367715_3	1237149.C900_02730	1.878e-34	138.0	COG1286@1|root,COG1286@2|Bacteria,4NRG9@976|Bacteroidetes,47S9N@768503|Cytophagia	976|Bacteroidetes	S	PFAM Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
TLS3_k127_6367715_2	643867.Ftrac_1783	4.823e-52	187.0	COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,47QJ2@768503|Cytophagia	976|Bacteroidetes	S	PFAM Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
TLS3_k127_6367715_0	1237149.C900_02732	1.471e-111	364.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,47K7U@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
TLS3_k127_6367715_1	1237149.C900_02735	4.267e-62	220.0	COG3762@1|root,COG3762@2|Bacteria	2|Bacteria	S	Membrane	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
TLS3_k127_6368654_3	1237149.C900_01223	2.902e-05	50.0	COG0135@1|root,COG0135@2|Bacteria,4NMKY@976|Bacteroidetes,47RUF@768503|Cytophagia	976|Bacteroidetes	E	PFAM N-(5'phosphoribosyl)anthranilate (PRA) isomerase	-	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
TLS3_k127_6368654_0	761193.Runsl_4442	1.372e-177	559.0	COG0388@1|root,COG0388@2|Bacteria,4NGWX@976|Bacteroidetes,47JH4@768503|Cytophagia	976|Bacteroidetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
TLS3_k127_6368654_2	398720.MED217_05662	1.088e-05	51.0	28XWV@1|root,2ZJT0@2|Bacteria,4P9A9@976|Bacteroidetes,1IBUT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6368654_1	1123248.KB893381_gene999	1.055e-160	507.0	COG1082@1|root,COG1082@2|Bacteria,4NK9X@976|Bacteroidetes	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
TLS3_k127_6372443_3	1120968.AUBX01000018_gene2165	1.207e-44	169.0	COG4775@1|root,COG4775@2|Bacteria,4NF38@976|Bacteroidetes,47KMS@768503|Cytophagia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6372443_0	1107311.Q767_10125	4.732e-86	291.0	COG3637@1|root,COG3637@2|Bacteria,4NPV9@976|Bacteroidetes,1I47X@117743|Flavobacteriia,2NSX3@237|Flavobacterium	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_6372443_5	1239962.C943_00133	4.705e-24	109.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	MA20_20735	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_6372443_4	1239962.C943_00137	2.786e-42	160.0	2CWBN@1|root,32SZD@2|Bacteria,4NU6S@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6372443_2	1121904.ARBP01000011_gene1461	2.194e-51	188.0	28N4A@1|root,2ZB9T@2|Bacteria,4NS50@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
TLS3_k127_6372443_1	1239962.C943_00991	1.326e-61	217.0	COG3047@1|root,COG3047@2|Bacteria,4NWCT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6385882_3	761193.Runsl_2797	5.21e-48	175.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,47JFD@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 20, catalytic core	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX,CHB_HEX_C,Glyco_hydro_20,Glyco_hydro_20b
TLS3_k127_6385882_1	1121904.ARBP01000043_gene2122	3.373e-137	447.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,47JVV@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
TLS3_k127_6385882_0	1121904.ARBP01000043_gene2122	4.025e-164	523.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,47JVV@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
TLS3_k127_6385882_2	1123277.KB893244_gene5151	1.18e-50	181.0	COG3292@1|root,COG3292@2|Bacteria,4NE4U@976|Bacteroidetes,47JHS@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6389850_0	1237149.C900_05294	1.57e-26	111.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_6389850_1	1123008.KB905699_gene1935	4.067e-11	64.0	COG4891@1|root,COG4891@2|Bacteria,4NQ7V@976|Bacteroidetes,2FVMT@200643|Bacteroidia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_6389850_2	926560.KE387023_gene3155	1.064e-10	64.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	1.20.4.3	ko:K03676,ko:K18917	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Glutaredoxin
TLS3_k127_6400546_2	926549.KI421517_gene2421	1.555e-59	214.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47MUE@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_6400546_1	700598.Niako_2573	2.097e-88	300.0	COG3391@1|root,COG3391@2|Bacteria,4PKC0@976|Bacteroidetes,1J0SQ@117747|Sphingobacteriia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6400546_0	1202532.FF52_07324	9.829e-186	589.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,1HYQE@117743|Flavobacteriia,2NUD5@237|Flavobacterium	976|Bacteroidetes	G	L-sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
TLS3_k127_6400546_3	1279009.ADICEAN_00021	6.748e-15	76.0	2AVB5@1|root,32VQE@2|Bacteria,4NSP1@976|Bacteroidetes,47RMG@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_640286_2	553178.CAPGI0001_2403	1.285e-101	350.0	COG3831@1|root,COG3831@2|Bacteria,4NJPG@976|Bacteroidetes,1I3DA@117743|Flavobacteriia,1EQZ7@1016|Capnocytophaga	976|Bacteroidetes	S	by glimmer	-	-	-	-	-	-	-	-	-	-	-	-	WGR
TLS3_k127_640286_0	553178.CAPGI0001_2405	7.615e-178	567.0	COG2345@1|root,COG2345@2|Bacteria,4NEDN@976|Bacteroidetes,1HZF2@117743|Flavobacteriia,1ER82@1016|Capnocytophaga	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
TLS3_k127_640286_1	485918.Cpin_3271	1.039e-151	489.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INWS@117747|Sphingobacteriia	976|Bacteroidetes	V	InterPro IPR003838	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_6410666_2	1408433.JHXV01000025_gene4054	1.282e-20	93.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,1HYTK@117743|Flavobacteriia,2PB8R@246874|Cryomorphaceae	976|Bacteroidetes	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,TSP_3
TLS3_k127_6410666_4	553177.CAPSP0001_2310	1.449e-10	66.0	2ENY6@1|root,33GJ1@2|Bacteria,4PEHC@976|Bacteroidetes,1IF2P@117743|Flavobacteriia,1ES66@1016|Capnocytophaga	976|Bacteroidetes	S	Immunity protein 40	-	-	-	-	-	-	-	-	-	-	-	-	Imm40
TLS3_k127_6410666_6	1121285.AUFK01000009_gene1263	7.52e-06	52.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,1HYTK@117743|Flavobacteriia,3ZNXS@59732|Chryseobacterium	976|Bacteroidetes	M	RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6410666_1	1121930.AQXG01000013_gene3290	1.971e-32	129.0	2FFX4@1|root,347U1@2|Bacteria,4P5XE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6410666_0	1121930.AQXG01000013_gene3291	7.746e-40	165.0	COG3209@1|root,COG3209@2|Bacteria,4NUPK@976|Bacteroidetes	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6410666_3	1235811.HMPREF0653_01199	1.483e-17	85.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	insA	GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0032196,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K07480,ko:K07489,ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	DDE_Tnp_IS1,HTH_Tnp_IS1,Zn_Tnp_IS1
TLS3_k127_6410666_5	32057.KB217478_gene1607	5.661e-06	52.0	2E321@1|root,32Y29@2|Bacteria,1G96S@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_64114_3	1237149.C900_03344	2.429e-08	57.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,47K6V@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
TLS3_k127_64114_2	1237149.C900_03345	1.269e-81	278.0	COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,47NSP@768503|Cytophagia	976|Bacteroidetes	J	PFAM SpoU rRNA Methylase family	aviRb	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
TLS3_k127_64114_1	1120968.AUBX01000009_gene653	2.257e-103	342.0	COG1738@1|root,COG1738@2|Bacteria,4NFP3@976|Bacteroidetes,47J8X@768503|Cytophagia	976|Bacteroidetes	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
TLS3_k127_64114_0	1237149.C900_04769	9.823e-116	379.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,47KGX@768503|Cytophagia	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
TLS3_k127_6434338_1	1237149.C900_05644	5.634e-105	351.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47N0R@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_6434338_0	1237149.C900_05633	6.587e-117	413.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NHSC@976|Bacteroidetes,47NEM@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator three Y	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,SpoIIE,Y_Y_Y
TLS3_k127_6434338_2	1189612.A33Q_3933	6.648e-81	274.0	COG2197@1|root,COG2197@2|Bacteria,4NR4G@976|Bacteroidetes,47UM2@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_6438617_2	313606.M23134_00219	2.146e-62	222.0	COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,47PMI@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_6438617_1	313606.M23134_00218	1.886e-85	289.0	COG3279@1|root,COG3279@2|Bacteria,4NI3K@976|Bacteroidetes,47PDV@768503|Cytophagia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_6438617_0	313606.M23134_06164	6.902e-107	365.0	COG1529@1|root,COG1529@2|Bacteria,4P0U8@976|Bacteroidetes,47T8N@768503|Cytophagia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
TLS3_k127_6440673_1	1033743.CAES01000046_gene314	7.924e-138	445.0	COG0329@1|root,COG0329@2|Bacteria,1UNIU@1239|Firmicutes,4HAWE@91061|Bacilli,26TG8@186822|Paenibacillaceae	91061|Bacilli	EM	dihydrodipicolinate synthetase	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
TLS3_k127_6440673_3	1239962.C943_01333	2.706e-107	357.0	COG0673@1|root,COG0673@2|Bacteria,4NHFK@976|Bacteroidetes,47MBN@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_6440673_2	391603.FBALC1_01942	3.305e-122	399.0	COG1834@1|root,COG1834@2|Bacteria,4NGKJ@976|Bacteroidetes,1I0NU@117743|Flavobacteriia	976|Bacteroidetes	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
TLS3_k127_6440673_0	1121875.KB907550_gene794	1.71e-154	499.0	COG0531@1|root,COG0531@2|Bacteria,4NIZB@976|Bacteroidetes,1HYXV@117743|Flavobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294,ko:K03758	-	-	-	-	ko00000,ko02000	2.A.3.2	-	-	AA_permease_2
TLS3_k127_6440673_4	1120968.AUBX01000009_gene432	1.871e-80	273.0	COG0726@1|root,COG0726@2|Bacteria,4NMJP@976|Bacteroidetes,47PNJ@768503|Cytophagia	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
TLS3_k127_6446144_2	1392498.JQLH01000001_gene285	4.259e-53	188.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1HXV2@117743|Flavobacteriia,2PI0B@252356|Maribacter	976|Bacteroidetes	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
TLS3_k127_6446144_1	509635.N824_22210	2.387e-77	267.0	COG0451@1|root,COG0451@2|Bacteria,4NMWC@976|Bacteroidetes,1ISPX@117747|Sphingobacteriia	976|Bacteroidetes	GM	epimerase	yeeZ	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,NAD_binding_2
TLS3_k127_6446144_0	468059.AUHA01000005_gene2429	5.033e-104	367.0	COG0642@1|root,COG3292@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1IRJZ@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA,PAS_9,Reg_prop,Response_reg,Y_Y_Y
TLS3_k127_6446876_1	1237149.C900_01990	5.145e-67	232.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, Crp Fnr family	crp	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
TLS3_k127_6446876_0	1237149.C900_01991	9.834e-120	397.0	COG0642@1|root,COG2205@2|Bacteria,4NG0Y@976|Bacteroidetes,47JUV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9
TLS3_k127_6446876_3	1124780.ANNU01000059_gene846	3.355e-05	52.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,47XGI@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_6446876_2	545695.TREAZ_2513	2.943e-19	98.0	COG2730@1|root,COG2730@2|Bacteria,2J89M@203691|Spirochaetes	203691|Spirochaetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
TLS3_k127_645021_5	153721.MYP_4441	1.039e-54	198.0	COG3091@1|root,COG3091@2|Bacteria,4NDXX@976|Bacteroidetes,47QAA@768503|Cytophagia	976|Bacteroidetes	S	PFAM SprT-like family	sprT	-	-	-	-	-	-	-	-	-	-	-	SprT-like
TLS3_k127_645021_2	1237149.C900_01164	3.943e-98	324.0	28M4Q@1|root,2ZAIK@2|Bacteria,4NJC3@976|Bacteroidetes,47P7F@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_645021_1	926549.KI421517_gene658	3.63e-118	385.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,47K6T@768503|Cytophagia	976|Bacteroidetes	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS
TLS3_k127_645021_3	1237149.C900_01166	1.547e-92	312.0	COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,47MGQ@768503|Cytophagia	976|Bacteroidetes	G	N-acetylglucosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
TLS3_k127_645021_7	485917.Phep_3698	1.544e-35	136.0	COG4892@1|root,COG4892@2|Bacteria,4NSAM@976|Bacteroidetes,1IYRW@117747|Sphingobacteriia	976|Bacteroidetes	S	Cytochrome b5-like Heme/Steroid binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cyt-b5
TLS3_k127_645021_6	1124780.ANNU01000051_gene2080	5.357e-51	189.0	COG1714@1|root,COG1714@2|Bacteria,4NH7U@976|Bacteroidetes,47P9X@768503|Cytophagia	976|Bacteroidetes	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
TLS3_k127_645021_0	760192.Halhy_4130	3.67e-172	551.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1IQAA@117747|Sphingobacteriia	976|Bacteroidetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
TLS3_k127_645021_4	1124780.ANNU01000051_gene2079	2.848e-68	238.0	COG1300@1|root,COG1300@2|Bacteria,4NG8D@976|Bacteroidetes,47MPK@768503|Cytophagia	976|Bacteroidetes	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
TLS3_k127_6465098_3	376686.Fjoh_1189	1.209e-107	372.0	COG4886@1|root,COG5184@1|root,COG4886@2|Bacteria,COG5184@2|Bacteria,4NMJ3@976|Bacteroidetes,1HZKN@117743|Flavobacteriia,2P053@237|Flavobacterium	976|Bacteroidetes	DZ	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LRR_4,Laminin_G_3,RCC1,SprB
TLS3_k127_6465098_0	1123277.KB893185_gene2965	4.217e-174	552.0	COG2267@1|root,COG2267@2|Bacteria,4NH5A@976|Bacteroidetes,47NQ8@768503|Cytophagia	976|Bacteroidetes	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6465098_5	714943.Mucpa_6579	7.388e-22	100.0	298VX@1|root,2ZVZZ@2|Bacteria,4P8YU@976|Bacteroidetes,1IZYD@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6465098_2	1484460.JSWG01000009_gene65	6.56e-124	402.0	COG0702@1|root,COG0702@2|Bacteria,4NH6G@976|Bacteroidetes,1HY8T@117743|Flavobacteriia	976|Bacteroidetes	GM	NmrA family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
TLS3_k127_6465098_4	926562.Oweho_0274	3.346e-52	188.0	COG5500@1|root,COG5500@2|Bacteria,4NR9R@976|Bacteroidetes,1I290@117743|Flavobacteriia	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1772
TLS3_k127_6465098_6	1122176.KB903554_gene3992	1.579e-20	95.0	COG3748@1|root,COG3748@2|Bacteria,4NXQD@976|Bacteroidetes	976|Bacteroidetes	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6465098_1	926562.Oweho_0272	2.704e-131	426.0	COG2207@1|root,COG2207@2|Bacteria,4NF5W@976|Bacteroidetes,1HYG8@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_6471155_4	929703.KE386491_gene1118	6.947e-156	494.0	COG2267@1|root,COG2267@2|Bacteria,4NFDA@976|Bacteroidetes,47NH1@768503|Cytophagia	976|Bacteroidetes	I	Serine aminopeptidase, S33	-	-	1.11.1.10,3.4.11.5	ko:K00433,ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Hydrolase_4
TLS3_k127_6471155_6	1123234.AUKI01000020_gene607	2.977e-25	107.0	2E3D8@1|root,32YCF@2|Bacteria,4NUPM@976|Bacteroidetes,1I544@117743|Flavobacteriia	976|Bacteroidetes	S	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_2
TLS3_k127_6471155_5	1123248.KB893315_gene3183	9.316e-124	402.0	COG0484@1|root,COG0484@2|Bacteria,4NE4X@976|Bacteroidetes,1IPQG@117747|Sphingobacteriia	976|Bacteroidetes	O	chaperone DnaJ	dnaJ2	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
TLS3_k127_6471155_8	269798.CHU_0933	6.502e-12	73.0	COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes	976|Bacteroidetes	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6471155_0	1270196.JCKI01000006_gene2622	5.08e-315	975.0	COG2382@1|root,COG2382@2|Bacteria,4NF50@976|Bacteroidetes,1IPKM@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG2382 Enterochelin esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,SASA
TLS3_k127_6471155_1	504472.Slin_1416	1.538e-301	930.0	COG3664@1|root,COG3664@2|Bacteria,4NHQ0@976|Bacteroidetes,47N7Z@768503|Cytophagia	976|Bacteroidetes	G	PFAM glycoside hydrolase family 39	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Glyco_hydro_39
TLS3_k127_6471155_2	504472.Slin_1412	1.403e-187	590.0	COG2382@1|root,COG2382@2|Bacteria,4NFVV@976|Bacteroidetes,47JT1@768503|Cytophagia	976|Bacteroidetes	P	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	CBM_48,Esterase
TLS3_k127_6471155_3	760192.Halhy_0495	5.672e-156	497.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
TLS3_k127_6471155_7	926549.KI421517_gene53	1.361e-12	67.0	COG2382@1|root,COG2382@2|Bacteria,4NHSA@976|Bacteroidetes,47MHN@768503|Cytophagia	976|Bacteroidetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	CBM_48,Esterase
TLS3_k127_6488524_1	700598.Niako_1733	1.743e-72	250.0	COG2197@1|root,COG2197@2|Bacteria,4NN4D@976|Bacteroidetes	976|Bacteroidetes	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_6488524_0	1267211.KI669560_gene463	6.903e-167	533.0	COG0657@1|root,COG4099@1|root,COG0657@2|Bacteria,COG4099@2|Bacteria,4PKKH@976|Bacteroidetes,1J0WF@117747|Sphingobacteriia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,DLH
TLS3_k127_6529073_5	929562.Emtol_2377	2.087e-51	190.0	COG0823@1|root,COG0823@2|Bacteria,4NITC@976|Bacteroidetes,47R0N@768503|Cytophagia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_6529073_0	1185876.BN8_04994	2.867e-164	526.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,47NNN@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
TLS3_k127_6529073_3	926549.KI421517_gene3893	1.188e-98	331.0	COG0598@1|root,COG0598@2|Bacteria,4NG3C@976|Bacteroidetes,47MH8@768503|Cytophagia	976|Bacteroidetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
TLS3_k127_6529073_7	1453500.AT05_08105	1.486e-27	120.0	2CC29@1|root,32RUM@2|Bacteria,4NS83@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6529073_4	1189612.A33Q_4138	8.153e-74	256.0	COG0500@1|root,COG2226@2|Bacteria,4NM9E@976|Bacteroidetes,47PMX@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
TLS3_k127_6529073_1	1356852.N008_10210	7.469e-130	424.0	COG3424@1|root,COG3424@2|Bacteria,4NDZU@976|Bacteroidetes,47JU1@768503|Cytophagia	976|Bacteroidetes	Q	PFAM chalcone and stilbene	bcsA	-	-	-	-	-	-	-	-	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
TLS3_k127_6529073_2	1237149.C900_01545	5.763e-107	354.0	COG0382@1|root,COG0382@2|Bacteria,4NK26@976|Bacteroidetes,47N2W@768503|Cytophagia	976|Bacteroidetes	H	UbiA prenyltransferase family	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
TLS3_k127_6529073_6	1237149.C900_03489	9.769e-47	171.0	COG0644@1|root,COG0644@2|Bacteria,4NE67@976|Bacteroidetes,47M1U@768503|Cytophagia	976|Bacteroidetes	C	FAD binding domain	fixC	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl,SE,Trp_halogenase
TLS3_k127_6540498_5	643867.Ftrac_0759	9.033e-46	172.0	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,47P8C@768503|Cytophagia	976|Bacteroidetes	S	Lipopolysaccharide-assembly	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
TLS3_k127_6540498_1	1237149.C900_05119	2.228e-203	639.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,47JXW@768503|Cytophagia	976|Bacteroidetes	K	sigma54 specific, transcriptional regulator, Fis family	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
TLS3_k127_6540498_0	1237149.C900_05118	2.435e-251	782.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,47MGS@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
TLS3_k127_6540498_2	1237149.C900_05115	1.033e-81	274.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,47PIB@768503|Cytophagia	976|Bacteroidetes	S	carbonic anhydrase acetyltransferase	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
TLS3_k127_6540498_3	1237149.C900_05111	4.933e-62	218.0	28Q4Y@1|root,2ZCN1@2|Bacteria,4NRPX@976|Bacteroidetes,47P9K@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6540498_4	1237149.C900_05109	5.411e-49	182.0	COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes,47MRT@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane chaperone Skp (OmpH)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TLS3_k127_6546357_2	1296416.JACB01000065_gene2662	3.779e-21	95.0	28IEX@1|root,2Z8GX@2|Bacteria,4NGBY@976|Bacteroidetes,1HY1B@117743|Flavobacteriia,2YIHW@290174|Aquimarina	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
TLS3_k127_6546357_1	1121904.ARBP01000002_gene6913	2.869e-194	608.0	COG0174@1|root,COG0174@2|Bacteria,4NGG2@976|Bacteroidetes,47JHR@768503|Cytophagia	976|Bacteroidetes	E	PFAM glutamine synthetase catalytic region	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
TLS3_k127_6546357_0	1237149.C900_05507	0.0	1490.0	COG1061@1|root,COG1112@1|root,COG1061@2|Bacteria,COG1112@2|Bacteria,4NF2S@976|Bacteroidetes,47KY5@768503|Cytophagia	976|Bacteroidetes	L	Superfamily I DNA and RNA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF4011
TLS3_k127_6562449_4	1296415.JACC01000011_gene573	1.403e-90	304.0	COG1349@1|root,COG1349@2|Bacteria,4NF6P@976|Bacteroidetes,1HZPR@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
TLS3_k127_6562449_1	880073.Calab_2834	1.541e-103	344.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_6562449_5	504472.Slin_3963	9.781e-70	243.0	COG2159@1|root,COG2159@2|Bacteria,4NH6P@976|Bacteroidetes,47M0D@768503|Cytophagia	976|Bacteroidetes	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_6562449_0	243090.RB2092	1.277e-122	404.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
TLS3_k127_6562449_2	1123278.KB893422_gene1617	2.469e-103	351.0	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,47M6K@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_6562449_3	1123248.KB893370_gene5123	4.956e-103	347.0	COG0702@1|root,COG0702@2|Bacteria,4NJQQ@976|Bacteroidetes,1IXE9@117747|Sphingobacteriia	976|Bacteroidetes	GM	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_6565293_1	1237149.C900_03266	1.394e-77	262.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,47K4U@768503|Cytophagia	976|Bacteroidetes	C	Quinol cytochrome c oxidoreductase membrane protein	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
TLS3_k127_6565293_0	1237149.C900_03265	9.681e-255	790.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,47K18@768503|Cytophagia	976|Bacteroidetes	C	PFAM Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
TLS3_k127_6565293_2	1120968.AUBX01000014_gene2322	7.322e-14	73.0	COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,47NK7@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S dicluster domain	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
TLS3_k127_6565756_2	1380600.AUYN01000006_gene440	0.0001171	48.0	2CCBM@1|root,2ZXWZ@2|Bacteria,4P8Y1@976|Bacteroidetes,1IBAU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6565756_0	118005.AWNK01000010_gene265	5.586e-56	203.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
TLS3_k127_6565756_1	1296416.JACB01000016_gene4458	2.059e-54	201.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1HX0V@117743|Flavobacteriia,2YIQF@290174|Aquimarina	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_6567283_3	649349.Lbys_2677	4.781e-08	54.0	COG0473@1|root,COG0473@2|Bacteria,4NEBE@976|Bacteroidetes,47MDN@768503|Cytophagia	976|Bacteroidetes	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
TLS3_k127_6567283_1	1121930.AQXG01000004_gene2960	1.37e-88	295.0	COG0066@1|root,COG0066@2|Bacteria,4NDVY@976|Bacteroidetes,1IQ0S@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
TLS3_k127_6567283_0	1185876.BN8_06126	7.447e-255	792.0	COG0065@1|root,COG0065@2|Bacteria,4NG7E@976|Bacteroidetes,47JAE@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
TLS3_k127_6567283_2	471854.Dfer_1578	2.591e-30	120.0	2C85M@1|root,31482@2|Bacteria,4NS0C@976|Bacteroidetes,47QCH@768503|Cytophagia	976|Bacteroidetes	S	PFAM Stress responsive alpha-beta barrel	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
TLS3_k127_6581178_2	1506583.JQJY01000002_gene1826	4.475e-61	216.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HZ6V@117743|Flavobacteriia,2NU6F@237|Flavobacterium	976|Bacteroidetes	V	Multidrug ABC transporter ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_6581178_1	485918.Cpin_6848	2.395e-124	406.0	COG4990@1|root,COG4990@2|Bacteria,4NFZX@976|Bacteroidetes,1IPPX@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4872)	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
TLS3_k127_6581178_4	485918.Cpin_6849	1.207e-34	137.0	2CE7N@1|root,30Q80@2|Bacteria,4NNKP@976|Bacteroidetes,1IT9G@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6581178_0	485918.Cpin_6850	2.597e-138	449.0	COG0332@1|root,COG0332@2|Bacteria,4NE5Q@976|Bacteroidetes,1IPV9@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	darB	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III_C,Thiolase_N,ketoacyl-synt
TLS3_k127_6581178_3	485918.Cpin_6851	2.517e-44	168.0	COG0716@1|root,COG0716@2|Bacteria,4NHTB@976|Bacteroidetes,1ISM3@117747|Sphingobacteriia	976|Bacteroidetes	C	Dialkylrecorsinol condensing enzyme DarA	darA	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6587461_6	471854.Dfer_2270	5.242e-46	173.0	2C34F@1|root,2ZA5Y@2|Bacteria,4NGPA@976|Bacteroidetes,47MYC@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6587461_3	1250232.JQNJ01000001_gene449	1.803e-141	469.0	COG1520@1|root,COG1520@2|Bacteria,4NFA9@976|Bacteroidetes,1I4P5@117743|Flavobacteriia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2,PQQ_3
TLS3_k127_6587461_5	313603.FB2170_11381	6.446e-74	263.0	COG1520@1|root,COG1520@2|Bacteria,4NFA9@976|Bacteroidetes,1I4P5@117743|Flavobacteriia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2,PQQ_3
TLS3_k127_6587461_0	1123248.KB893317_gene4292	0.0	1014.0	COG0613@1|root,COG0613@2|Bacteria,4PN3D@976|Bacteroidetes	976|Bacteroidetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6587461_2	929713.NIASO_07480	2.236e-192	627.0	COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_6587461_4	1123057.P872_19455	1.556e-140	459.0	COG0726@1|root,COG0726@2|Bacteria,4PHTX@976|Bacteroidetes,47SCN@768503|Cytophagia	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
TLS3_k127_6587461_1	1239962.C943_04042	4.409e-233	728.0	COG5297@1|root,COG5297@2|Bacteria,4NG19@976|Bacteroidetes,47KXX@768503|Cytophagia	976|Bacteroidetes	G	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1593
TLS3_k127_6587461_7	1121481.AUAS01000018_gene480	8.719e-27	109.0	2CJ4Q@1|root,32S97@2|Bacteria,4NTZM@976|Bacteroidetes,47X4A@768503|Cytophagia	976|Bacteroidetes	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD
TLS3_k127_6593834_0	485918.Cpin_1424	2.808e-277	875.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1IQA8@117747|Sphingobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF5118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
TLS3_k127_6593834_4	395493.BegalDRAFT_2288	1.859e-23	112.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_6593834_1	485918.Cpin_2165	8.699e-136	448.0	COG4251@1|root,COG5278@1|root,COG4251@2|Bacteria,COG5278@2|Bacteria,4NIJY@976|Bacteroidetes	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA
TLS3_k127_6593834_2	1123248.KB893337_gene2358	3.184e-50	181.0	COG3437@1|root,COG3437@2|Bacteria,4PN7C@976|Bacteroidetes	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_6593834_3	376686.Fjoh_4842	1.49e-36	140.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,4NE3J@976|Bacteroidetes,1HXNX@117743|Flavobacteriia,2NU9V@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
TLS3_k127_6600885_0	1341155.FSS13T_20080	5.83e-190	604.0	COG0001@1|root,COG1861@1|root,COG0001@2|Bacteria,COG1861@2|Bacteria,4NDXG@976|Bacteroidetes,1HWQS@117743|Flavobacteriia,2NV7V@237|Flavobacterium	976|Bacteroidetes	HM	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,CTP_transf_3
TLS3_k127_6600885_6	1094466.KQS_04785	7.222e-81	280.0	COG1670@1|root,COG1670@2|Bacteria,4NTTP@976|Bacteroidetes,1ICUN@117743|Flavobacteriia,2NUZK@237|Flavobacterium	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,Acetyltransf_4
TLS3_k127_6600885_1	926549.KI421517_gene3885	1.854e-162	517.0	COG2089@1|root,COG2089@2|Bacteria,4NEKD@976|Bacteroidetes,47M91@768503|Cytophagia	976|Bacteroidetes	M	NeuB family	pseI	-	2.5.1.56,2.5.1.97	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
TLS3_k127_6600885_4	929713.NIASO_01455	3.927e-106	355.0	COG0037@1|root,COG0037@2|Bacteria,4NIZR@976|Bacteroidetes,1IZJG@117747|Sphingobacteriia	976|Bacteroidetes	D	LPS biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_synthase
TLS3_k127_6600885_10	1408433.JHXV01000029_gene3117	1.526e-44	177.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4
TLS3_k127_6600885_2	1121481.AUAS01000011_gene5150	7.335e-136	443.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,47U25@768503|Cytophagia	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.23	ko:K13019	ko00520,map00520	-	R09600	RC00290	ko00000,ko00001,ko01000,ko01005	-	-	-	Epimerase_2
TLS3_k127_6600885_5	755732.Fluta_2190	1.765e-92	307.0	COG2120@1|root,COG2120@2|Bacteria,4NN16@976|Bacteroidetes	976|Bacteroidetes	S	PFAM N-acetylglucosaminyl phosphatidylinositol deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TLS3_k127_6600885_7	755732.Fluta_2191	4.051e-73	258.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1HWJD@117743|Flavobacteriia,2PAFN@246874|Cryomorphaceae	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
TLS3_k127_6600885_3	313598.MED152_05000	8.776e-121	398.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,1HXDA@117743|Flavobacteriia,3VWNZ@52959|Polaribacter	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
TLS3_k127_6600885_8	886379.AEWI01000052_gene2670	1.77e-63	231.0	COG0438@1|root,COG0438@2|Bacteria,4NZMT@976|Bacteroidetes,2G1JS@200643|Bacteroidia,3XKI2@558415|Marinilabiliaceae	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
TLS3_k127_6600885_9	1170562.Cal6303_5334	1.616e-46	175.0	COG4627@1|root,COG4627@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
TLS3_k127_6609464_6	1237149.C900_05600	1.965e-17	85.0	2DM6B@1|root,31WK9@2|Bacteria,4NQK1@976|Bacteroidetes,47QS1@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
TLS3_k127_6609464_1	1237149.C900_05598	3.413e-159	511.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,47KKP@768503|Cytophagia	976|Bacteroidetes	F	TIGRFAM dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
TLS3_k127_6609464_0	1237149.C900_05597	9.433e-188	607.0	COG1361@1|root,COG1361@2|Bacteria,4PKPA@976|Bacteroidetes	976|Bacteroidetes	M	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB
TLS3_k127_6609464_2	1237149.C900_05594	7.939e-48	173.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,47RWZ@768503|Cytophagia	976|Bacteroidetes	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
TLS3_k127_6609464_4	1137281.D778_02016	2.953e-37	144.0	COG4068@1|root,COG4068@2|Bacteria,4NQ3Z@976|Bacteroidetes,1I2T2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
TLS3_k127_6609464_3	1313421.JHBV01000016_gene5721	1.089e-44	167.0	2C3PP@1|root,2Z954@2|Bacteria,4NIZX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6614947_0	1123248.KB893348_gene172	1.289e-113	375.0	COG0491@1|root,COG0491@2|Bacteria,4NF10@976|Bacteroidetes,1IS5K@117747|Sphingobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_6614947_2	1300143.CCAV010000003_gene2323	1.95e-87	295.0	COG2513@1|root,COG2513@2|Bacteria,4NMEH@976|Bacteroidetes,1I2BJ@117743|Flavobacteriia,3ZPSK@59732|Chryseobacterium	976|Bacteroidetes	G	Carboxyvinyl-carboxyphosphonate phosphorylmutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
TLS3_k127_6614947_1	1185876.BN8_06457	1.612e-99	340.0	COG2207@1|root,COG2207@2|Bacteria,4NRBA@976|Bacteroidetes,47S2G@768503|Cytophagia	976|Bacteroidetes	K	Arabinose-binding domain of AraC transcription regulator, N-term	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
TLS3_k127_6614947_3	929556.Solca_1688	1.858e-38	149.0	COG3631@1|root,COG3631@2|Bacteria,4NQEU@976|Bacteroidetes,1ITSK@117747|Sphingobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
TLS3_k127_6614947_4	1121373.KB903654_gene1709	3.263e-26	108.0	COG1132@1|root,COG1132@2|Bacteria,4NEBS@976|Bacteroidetes,47K10@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS3_k127_6617843_2	926549.KI421517_gene2837	4.776e-33	130.0	COG3622@1|root,COG3622@2|Bacteria,4NG0V@976|Bacteroidetes,47M10@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the hyi family	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
TLS3_k127_6617843_1	1123248.KB893325_gene1170	5.922e-151	481.0	COG3622@1|root,COG3622@2|Bacteria,4NG0V@976|Bacteroidetes,1INUU@117747|Sphingobacteriia	976|Bacteroidetes	G	Hydroxypyruvate isomerase	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
TLS3_k127_6617843_0	1392488.JHZY01000002_gene579	2.485e-188	608.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia,2XJ0R@283735|Leeuwenhoekiella	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
TLS3_k127_6622978_0	714943.Mucpa_0292	1.516e-37	146.0	COG4319@1|root,COG4319@2|Bacteria,4NSGY@976|Bacteroidetes,1ITKP@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
TLS3_k127_6622978_2	1198114.AciX9_2171	5.387e-16	91.0	COG3391@1|root,COG4257@1|root,COG3391@2|Bacteria,COG4257@2|Bacteria,3Y6FJ@57723|Acidobacteria,2JP7B@204432|Acidobacteriia	204432|Acidobacteriia	V	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	NHL
TLS3_k127_6622978_1	929556.Solca_0470	3.084e-35	140.0	2DN71@1|root,32VWQ@2|Bacteria,4NWUU@976|Bacteroidetes,1IU54@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA_like
TLS3_k127_6630497_0	925409.KI911562_gene1684	5.843e-78	271.0	2CEP6@1|root,314NU@2|Bacteria,4NQE8@976|Bacteroidetes,1ISQY@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
TLS3_k127_6637544_1	1121904.ARBP01000024_gene6659	9.274e-180	580.0	COG0561@1|root,COG0561@2|Bacteria,4NFSF@976|Bacteroidetes,47MAQ@768503|Cytophagia	976|Bacteroidetes	S	PFAM RagB SusD domain protein	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_6637544_0	1121904.ARBP01000024_gene6660	0.0	1077.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47Y7H@768503|Cytophagia	976|Bacteroidetes	H	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_6647369_2	471854.Dfer_1603	7.935e-24	104.0	COG1621@1|root,COG1621@2|Bacteria,4NEYI@976|Bacteroidetes,47KIP@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
TLS3_k127_6647369_1	504472.Slin_2652	4.181e-125	406.0	COG1082@1|root,COG1082@2|Bacteria,4NFMD@976|Bacteroidetes,47JA9@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_6647369_0	700598.Niako_3218	2.546e-162	521.0	28HII@1|root,2Z7TZ@2|Bacteria,4NHR6@976|Bacteroidetes,1INR1@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6647369_3	313628.LNTAR_11421	9.86e-19	91.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
TLS3_k127_6660695_0	471854.Dfer_1979	1.912e-219	690.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,47MIN@768503|Cytophagia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
TLS3_k127_6660695_2	153721.MYP_3093	1.36e-84	286.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,47PTI@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_6660695_1	153721.MYP_3092	1.349e-98	344.0	COG0457@1|root,COG2972@1|root,COG0457@2|Bacteria,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,47QDQ@768503|Cytophagia	976|Bacteroidetes	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,TPR_12,TPR_16,TPR_7,TPR_8
TLS3_k127_6675754_0	1237149.C900_01813	1.963e-233	746.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,47KIF@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
TLS3_k127_6675754_1	1237149.C900_01814	4.516e-130	427.0	COG2067@1|root,COG2067@2|Bacteria,4NDZW@976|Bacteroidetes,47KQT@768503|Cytophagia	976|Bacteroidetes	I	long-chain fatty acid transport protein	porV	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6675754_2	1121481.AUAS01000008_gene2939	4.153e-90	312.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,47JF1@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_6680735_2	1237149.C900_01061	1.207e-66	228.0	COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,47Q07@768503|Cytophagia	976|Bacteroidetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
TLS3_k127_6680735_3	1120965.AUBV01000003_gene578	2.111e-59	207.0	COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,47PRH@768503|Cytophagia	976|Bacteroidetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
TLS3_k127_6680735_5	761193.Runsl_1678	1.036e-14	74.0	COG0257@1|root,COG0257@2|Bacteria,4NXGE@976|Bacteroidetes,47SMT@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
TLS3_k127_6680735_4	1237149.C900_01058	3.905e-36	137.0	COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,47RFD@768503|Cytophagia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
TLS3_k127_6680735_1	1237149.C900_01057	1.175e-123	400.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,47KDT@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
TLS3_k127_6680735_0	1237149.C900_01056	2.197e-166	528.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,47JRD@768503|Cytophagia	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
TLS3_k127_6696102_2	1308866.J416_02089	1.751e-14	86.0	COG2244@1|root,COG2244@2|Bacteria,1TR7A@1239|Firmicutes,4HEKF@91061|Bacilli	91061|Bacilli	S	Polysaccharide biosynthesis protein	cps2J	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
TLS3_k127_6696102_0	509635.N824_26245	1.165e-156	501.0	COG0399@1|root,COG0399@2|Bacteria,4NGI4@976|Bacteroidetes,1IPNX@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	vioA	-	2.6.1.33	ko:K20429	-	-	R02773	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_6696102_1	743722.Sph21_2024	6.521e-51	195.0	2DMHZ@1|root,32RNI@2|Bacteria,4NTBA@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_56
TLS3_k127_6706271_4	1121890.AUDO01000015_gene3035	2.636e-22	96.0	arCOG12631@1|root,3172B@2|Bacteria,4NQ4C@976|Bacteroidetes,1I1XB@117743|Flavobacteriia,2NW9Q@237|Flavobacterium	976|Bacteroidetes	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_1
TLS3_k127_6706271_0	1095752.HMPREF9969_2502	7.106e-78	286.0	COG4206@1|root,COG4206@2|Bacteria,4PNIK@976|Bacteroidetes	976|Bacteroidetes	H	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
TLS3_k127_6706271_1	1120966.AUBU01000017_gene694	3.047e-40	158.0	COG3063@1|root,COG3063@2|Bacteria,4NTEN@976|Bacteroidetes,47VMA@768503|Cytophagia	976|Bacteroidetes	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
TLS3_k127_6706271_5	1237149.C900_03334	2.513e-16	85.0	2DTU1@1|root,33MMF@2|Bacteria,4NWD8@976|Bacteroidetes,47SX0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6706271_2	1237149.C900_03336	5.622e-39	147.0	COG1846@1|root,COG1846@2|Bacteria,4PKFS@976|Bacteroidetes,47V9T@768503|Cytophagia	976|Bacteroidetes	K	Winged helix DNA-binding domain	marR	-	-	-	-	-	-	-	-	-	-	-	HTH_34
TLS3_k127_6706271_3	1237149.C900_03337	1.89e-38	149.0	295IV@1|root,2ZSWC@2|Bacteria,4NVMA@976|Bacteroidetes,47W1I@768503|Cytophagia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6710768_1	1237149.C900_00918	6.324e-80	271.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,47K49@768503|Cytophagia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
TLS3_k127_6710768_4	761193.Runsl_4392	9.598e-16	84.0	COG0526@1|root,COG0526@2|Bacteria,4NV2M@976|Bacteroidetes,47X7E@768503|Cytophagia	976|Bacteroidetes	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_2
TLS3_k127_6710768_0	1237149.C900_00914	3.547e-95	325.0	COG0742@1|root,COG0742@2|Bacteria,4NG6E@976|Bacteroidetes,47YDK@768503|Cytophagia	976|Bacteroidetes	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95,PCMT
TLS3_k127_6710768_2	1237149.C900_00106	3.771e-61	217.0	COG3952@1|root,COG3952@2|Bacteria,4NH8Q@976|Bacteroidetes,47YQ6@768503|Cytophagia	976|Bacteroidetes	S	Lipid A Biosynthesis N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
TLS3_k127_6710768_3	1123248.KB893315_gene2997	1.667e-20	92.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,1IP0F@117747|Sphingobacteriia	976|Bacteroidetes	S	HI0933 family	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
TLS3_k127_671617_5	926549.KI421517_gene2007	3.673e-104	359.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_671617_4	1237149.C900_01603	2.658e-118	388.0	COG0009@1|root,COG0009@2|Bacteria,4NF5U@976|Bacteroidetes,47KX9@768503|Cytophagia	976|Bacteroidetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua5	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
TLS3_k127_671617_3	929556.Solca_1205	1.864e-137	445.0	COG2367@1|root,COG2367@2|Bacteria,4NDYP@976|Bacteroidetes,1INNE@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
TLS3_k127_671617_8	929562.Emtol_3718	4.334e-54	196.0	COG1051@1|root,COG1051@2|Bacteria,4NNJ5@976|Bacteroidetes,47PUZ@768503|Cytophagia	976|Bacteroidetes	F	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_671617_0	925409.KI911562_gene1384	2.125e-214	674.0	COG1082@1|root,COG2152@1|root,COG1082@2|Bacteria,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes,1IQ4Y@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
TLS3_k127_671617_6	1124780.ANNU01000008_gene2664	1.268e-99	335.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,47ME3@768503|Cytophagia	976|Bacteroidetes	K	PFAM Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
TLS3_k127_671617_9	760192.Halhy_4846	1.593e-40	158.0	COG1595@1|root,COG1595@2|Bacteria,4PIXB@976|Bacteroidetes,1IZ59@117747|Sphingobacteriia	976|Bacteroidetes	K	COGs COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_671617_7	1121097.JCM15093_306	3.997e-98	328.0	COG1028@1|root,COG1028@2|Bacteria,4NG8R@976|Bacteroidetes,2FMB9@200643|Bacteroidia,4AM6Q@815|Bacteroidaceae	976|Bacteroidetes	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	uxuB	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
TLS3_k127_671617_2	926549.KI421517_gene3710	1.858e-179	569.0	COG1312@1|root,COG1312@2|Bacteria,4NFA5@976|Bacteroidetes,47JUT@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the dehydration of D-mannonate	uxuA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0008198,GO:0008927,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019585,GO:0019752,GO:0030145,GO:0032787,GO:0042839,GO:0042840,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0046914,GO:0071704,GO:0072329,GO:1901575	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
TLS3_k127_671617_1	641524.ADICYQ_5878	3.385e-203	641.0	COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes,47KAP@768503|Cytophagia	976|Bacteroidetes	G	Glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
TLS3_k127_6732006_4	1120965.AUBV01000012_gene1394	1.405e-23	104.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
TLS3_k127_6732006_0	1317122.ATO12_19400	1.658e-104	347.0	COG2801@1|root,COG2801@2|Bacteria,4NF3Q@976|Bacteroidetes,1HZT4@117743|Flavobacteriia,2YK2V@290174|Aquimarina	976|Bacteroidetes	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
TLS3_k127_6732006_2	1453505.JASY01000013_gene4331	3.843e-72	256.0	2DPT6@1|root,3339Y@2|Bacteria,4PNFC@976|Bacteroidetes,1IKPI@117743|Flavobacteriia	976|Bacteroidetes	S	DKNYY family	-	-	-	-	-	-	-	-	-	-	-	-	DKNYY
TLS3_k127_6732006_3	1123248.KB893314_gene3665	5.918e-30	123.0	COG0745@1|root,COG0745@2|Bacteria	1123248.KB893314_gene3665|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6732006_5	700598.Niako_3962	1.825e-15	77.0	COG0745@1|root,COG0745@2|Bacteria,4NPID@976|Bacteroidetes	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_6732006_1	761193.Runsl_4417	2.663e-93	314.0	COG4251@1|root,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,47KWE@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
TLS3_k127_673227_3	1123277.KB893176_gene3718	5.634e-65	234.0	COG3712@1|root,COG3712@2|Bacteria,4NSEH@976|Bacteroidetes,47RNC@768503|Cytophagia	976|Bacteroidetes	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
TLS3_k127_673227_0	1121904.ARBP01000008_gene3411	0.0	1712.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47NEI@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_673227_1	1121904.ARBP01000008_gene3412	1.134e-311	962.0	COG0457@1|root,COG0457@2|Bacteria,4NDX0@976|Bacteroidetes,47MNP@768503|Cytophagia	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_673227_2	760192.Halhy_1895	1.93e-98	328.0	COG4225@1|root,COG4225@2|Bacteria,4NF1N@976|Bacteroidetes,1IP96@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Heparinase II III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
TLS3_k127_6738865_2	382464.ABSI01000012_gene2185	3.951e-46	170.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Copper-bind,Cytochrom_C,Laminin_G_3
TLS3_k127_6738865_1	1124780.ANNU01000025_gene3372	8.76e-55	196.0	COG1846@1|root,COG1846@2|Bacteria,4NP8N@976|Bacteroidetes,47PSY@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
TLS3_k127_6738865_0	1124780.ANNU01000025_gene3371	5.845e-176	555.0	COG0492@1|root,COG0492@2|Bacteria,4NEQM@976|Bacteroidetes,47KZW@768503|Cytophagia	976|Bacteroidetes	C	Ferredoxin--NADP reductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_6738865_3	1123277.KB893244_gene5046	3.36e-40	151.0	COG0633@1|root,COG0633@2|Bacteria,4NQ4P@976|Bacteroidetes,47QBT@768503|Cytophagia	976|Bacteroidetes	C	Ferredoxin	thcC	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
TLS3_k127_6777510_2	388413.ALPR1_17088	2.144e-52	191.0	COG3712@1|root,COG3712@2|Bacteria,4NREY@976|Bacteroidetes,47Q61@768503|Cytophagia	976|Bacteroidetes	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
TLS3_k127_6777510_0	388413.ALPR1_17083	0.0	1687.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47Y4V@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
TLS3_k127_6777510_1	388413.ALPR1_17078	3.998e-126	410.0	COG4198@1|root,COG4198@2|Bacteria,4NEAX@976|Bacteroidetes,47Y4U@768503|Cytophagia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_2
TLS3_k127_6777847_1	1237149.C900_04087	3.27e-94	319.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes	976|Bacteroidetes	V	permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_6777847_0	1237149.C900_03297	2.548e-191	610.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,47JHJ@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase M13	pepO	-	3.4.24.71	ko:K01415,ko:K07386	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
TLS3_k127_6785680_0	153721.MYP_2351	4.811e-299	938.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,47K5C@768503|Cytophagia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
TLS3_k127_6785680_1	761193.Runsl_3430	3.348e-65	225.0	COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,47PSE@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
TLS3_k127_6792652_0	643867.Ftrac_0021	1.323e-319	988.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,47KGW@768503|Cytophagia	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
TLS3_k127_6792652_1	1124780.ANNU01000003_gene1418	1.29e-87	295.0	COG4221@1|root,COG4221@2|Bacteria,4NG8J@976|Bacteroidetes,47M5I@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_6797539_1	1237149.C900_02648	2.242e-111	366.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,47Q1V@768503|Cytophagia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_6797539_2	1237149.C900_02649	1.264e-71	250.0	COG1277@1|root,COG1277@2|Bacteria,4NEES@976|Bacteroidetes,47WZW@768503|Cytophagia	976|Bacteroidetes	S	Excinuclease ABC subunit B	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4
TLS3_k127_6797539_0	1120951.AUBG01000002_gene1393	2.94e-177	569.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,1HX66@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
TLS3_k127_6799359_10	1303518.CCALI_02909	2.142e-21	98.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ytaP	-	-	-	-	-	-	-	-	-	-	-	AXE1,Abhydrolase_7,DLH,Peptidase_S15,Peptidase_S9
TLS3_k127_6799359_0	1120965.AUBV01000003_gene270	2.351e-303	938.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,47JC8@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
TLS3_k127_6799359_7	1237149.C900_00723	6.629e-49	181.0	2E7DW@1|root,331WY@2|Bacteria,4NUZQ@976|Bacteroidetes,47RNZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6799359_5	1124780.ANNU01000006_gene2814	1.534e-61	214.0	COG0590@1|root,COG0590@2|Bacteria,4NNJ2@976|Bacteroidetes,47PPY@768503|Cytophagia	976|Bacteroidetes	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
TLS3_k127_6799359_8	269798.CHU_3583	2.145e-38	146.0	2DMPT@1|root,32SXV@2|Bacteria,4PKGT@976|Bacteroidetes,47R1K@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
TLS3_k127_6799359_3	929556.Solca_3503	4.878e-106	346.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,1IQF9@117747|Sphingobacteriia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
TLS3_k127_6799359_9	643867.Ftrac_1189	7.956e-27	111.0	2DXSD@1|root,346A9@2|Bacteria,4P5K0@976|Bacteroidetes,47VQR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6799359_6	1270196.JCKI01000003_gene1889	6.874e-51	183.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_3
TLS3_k127_6799359_1	468059.AUHA01000006_gene2865	1.585e-187	593.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1INY6@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
TLS3_k127_6799359_2	1122605.KB893626_gene2452	3.667e-122	400.0	COG2908@1|root,COG2908@2|Bacteria,4PNWQ@976|Bacteroidetes,1J0UM@117747|Sphingobacteriia	976|Bacteroidetes	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
TLS3_k127_6799359_4	1123248.KB893370_gene5027	4.095e-104	344.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes	976|Bacteroidetes	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_6802869_1	1120965.AUBV01000007_gene2631	7.888e-119	387.0	COG4299@1|root,COG4299@2|Bacteria,4NGKU@976|Bacteroidetes,47M78@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
TLS3_k127_6802869_0	1123277.KB893194_gene5874	2.584e-301	945.0	COG1680@1|root,COG3653@1|root,COG1680@2|Bacteria,COG3653@2|Bacteria,4NI1Z@976|Bacteroidetes,47NHH@768503|Cytophagia	976|Bacteroidetes	QV	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3,Beta-lactamase
TLS3_k127_6802869_2	926549.KI421517_gene3694	1.648e-37	144.0	COG3222@1|root,COG3222@2|Bacteria,4NM7F@976|Bacteroidetes,47PF2@768503|Cytophagia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
TLS3_k127_6816434_0	1173021.ALWA01000008_gene1504	4.015e-162	535.0	COG0514@1|root,COG0514@2|Bacteria,1G1Y1@1117|Cyanobacteria	1117|Cyanobacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
TLS3_k127_6816434_1	1408813.AYMG01000039_gene2339	2.868e-159	517.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,1IQSQ@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
TLS3_k127_6817553_4	643867.Ftrac_2755	7.17e-19	95.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF_2,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg,Y_Y_Y
TLS3_k127_6817553_5	1268240.ATFI01000013_gene1178	1.436e-05	49.0	2DR32@1|root,339YJ@2|Bacteria,4NYM3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6817553_0	1305737.JAFX01000001_gene2160	2.37e-188	597.0	COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,47JED@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
TLS3_k127_6817553_1	1237149.C900_00900	3.309e-143	456.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,47KRT@768503|Cytophagia	976|Bacteroidetes	C	PFAM Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
TLS3_k127_6817553_2	1121859.KB890738_gene3069	2.507e-43	163.0	28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,47RCF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6817553_3	1237149.C900_00894	2.362e-30	123.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47JJM@768503|Cytophagia	976|Bacteroidetes	MU	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
TLS3_k127_6826840_1	1123277.KB893182_gene4757	6.907e-34	135.0	COG3712@1|root,COG3712@2|Bacteria,4P067@976|Bacteroidetes,47TAK@768503|Cytophagia	976|Bacteroidetes	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
TLS3_k127_6826840_0	1121481.AUAS01000003_gene4085	2.141e-194	624.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47Y2H@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_6864421_0	1237149.C900_02391	1.736e-239	746.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47P32@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
TLS3_k127_6864421_1	760192.Halhy_6209	7.648e-92	308.0	COG2834@1|root,COG2834@2|Bacteria,4NHV3@976|Bacteroidetes,1IZ7F@117747|Sphingobacteriia	976|Bacteroidetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292,LolA_like
TLS3_k127_6864421_2	1237149.C900_00062	1.135e-64	226.0	COG1131@1|root,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,47KQD@768503|Cytophagia	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,TerB
TLS3_k127_6886292_1	1237149.C900_00593	3.272e-90	301.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,47JJU@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS3_k127_6886292_3	471854.Dfer_4013	4.745e-62	227.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,47NU0@768503|Cytophagia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS3_k127_6886292_0	1237149.C900_00595	1.119e-91	305.0	COG5405@1|root,COG5405@2|Bacteria,4NHZ8@976|Bacteroidetes,47MJS@768503|Cytophagia	976|Bacteroidetes	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
TLS3_k127_6886292_2	1237149.C900_00596	1.763e-80	269.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,47KP4@768503|Cytophagia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS3_k127_6890638_2	471854.Dfer_2270	2.597e-108	360.0	2C34F@1|root,2ZA5Y@2|Bacteria,4NGPA@976|Bacteroidetes,47MYC@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6890638_1	760192.Halhy_5492	6.034e-126	417.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,Beta-lactamase
TLS3_k127_6890638_0	1121904.ARBP01000030_gene1946	0.0	1129.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47KU3@768503|Cytophagia	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
TLS3_k127_6890638_3	1194972.MVAC_20123	1.811e-44	170.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6894273_0	643867.Ftrac_2129	7.33e-140	467.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,47KCA@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
TLS3_k127_6894273_1	649349.Lbys_3178	1.558e-10	63.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,47M71@768503|Cytophagia	976|Bacteroidetes	T	Signal transduction histidine kinase	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_6898399_3	643867.Ftrac_0790	2.292e-70	241.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,47PZ4@768503|Cytophagia	976|Bacteroidetes	O	peptide methionine sulfoxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
TLS3_k127_6898399_0	929703.KE386491_gene2861	1.139e-188	598.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,47KAQ@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
TLS3_k127_6898399_1	1237149.C900_05610	2.837e-175	556.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,47KY6@768503|Cytophagia	976|Bacteroidetes	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	dmpP	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
TLS3_k127_6898399_2	1122605.KB893647_gene312	1.942e-86	290.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,1IP0G@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
TLS3_k127_690080_1	1120965.AUBV01000014_gene1226	3.062e-06	52.0	COG3119@1|root,COG3119@2|Bacteria,4NE9D@976|Bacteroidetes,47T9R@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TLS3_k127_690080_0	1121904.ARBP01000013_gene365	0.0	1552.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4NH6B@976|Bacteroidetes,47MFW@768503|Cytophagia	976|Bacteroidetes	C	PFAM PBS lyase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH,HEAT_2
TLS3_k127_6903641_0	1150600.ADIARSV_1981	8.573e-164	527.0	COG1086@1|root,COG1086@2|Bacteria,4P26E@976|Bacteroidetes	976|Bacteroidetes	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_2
TLS3_k127_6903641_3	700598.Niako_0097	1.374e-29	122.0	COG1310@1|root,COG1310@2|Bacteria,4NTI0@976|Bacteroidetes,1ITYI@117747|Sphingobacteriia	976|Bacteroidetes	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
TLS3_k127_6903641_2	641524.ADICYQ_3763	1.031e-29	120.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,4NFUD@976|Bacteroidetes,47KG8@768503|Cytophagia	976|Bacteroidetes	H	MoeZ MoeB domain	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
TLS3_k127_6903641_1	700598.Niako_0098	4.453e-135	432.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,4NFUD@976|Bacteroidetes,1IPBH@117747|Sphingobacteriia	976|Bacteroidetes	H	UBA THIF-type NAD FAD binding protein	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
TLS3_k127_6917146_1	1408813.AYMG01000010_gene441	5.389e-128	419.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1IPZG@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_6917146_5	1121007.AUML01000007_gene2962	7.075e-29	120.0	2C0VV@1|root,32R2M@2|Bacteria,4NQM5@976|Bacteroidetes,1I3U1@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6917146_3	1123248.KB893316_gene4610	1.564e-111	369.0	COG1988@1|root,COG1988@2|Bacteria,4NFBT@976|Bacteroidetes,1IYQQ@117747|Sphingobacteriia	976|Bacteroidetes	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
TLS3_k127_6917146_2	700598.Niako_3669	1.634e-123	407.0	COG1502@1|root,COG1502@2|Bacteria,4P0CZ@976|Bacteroidetes,1J0D9@117747|Sphingobacteriia	976|Bacteroidetes	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
TLS3_k127_6917146_0	643867.Ftrac_0656	7.017e-241	753.0	COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,47JPR@768503|Cytophagia	976|Bacteroidetes	E	PFAM Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
TLS3_k127_6917146_4	269798.CHU_1092	1.923e-63	232.0	COG0457@1|root,COG4251@1|root,COG0457@2|Bacteria,COG4251@2|Bacteria,4NNCE@976|Bacteroidetes,47UGZ@768503|Cytophagia	976|Bacteroidetes	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,TPR_12
TLS3_k127_6917146_6	880071.Fleli_3391	7.028e-27	124.0	COG2208@1|root,COG2208@2|Bacteria,4NYPG@976|Bacteroidetes,47UHH@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,SpoIIE
TLS3_k127_6925286_0	1189620.AJXL01000042_gene598	3.057e-114	411.0	COG0642@1|root,COG4251@1|root,COG2205@2|Bacteria,COG4251@2|Bacteria,4NDXU@976|Bacteroidetes,1HY32@117743|Flavobacteriia,2NSQ1@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Response_reg
TLS3_k127_6925286_2	1267211.KI669560_gene2033	6.781e-30	139.0	COG3452@1|root,COG3452@2|Bacteria,4NI9G@976|Bacteroidetes	976|Bacteroidetes	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_3
TLS3_k127_6925286_1	497965.Cyan7822_4408	4.09e-36	142.0	COG0642@1|root,COG1716@1|root,COG4191@1|root,COG1716@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria,1G09B@1117|Cyanobacteria,3KJSP@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_2,HATPase_c,HisKA,PAS,PAS_4
TLS3_k127_6925957_0	1237149.C900_03353	4.483e-305	940.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,47J97@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_6925957_1	485918.Cpin_4936	2.19e-119	390.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1IX1T@117747|Sphingobacteriia	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
TLS3_k127_6925957_2	1189619.pgond44_13788	2.573e-59	211.0	2CHF5@1|root,33W1U@2|Bacteria,4P3CK@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6928242_4	700598.Niako_1915	2.588e-55	198.0	COG0673@1|root,COG0673@2|Bacteria,4NG5T@976|Bacteroidetes,1IRR9@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,Oxidoreduct_C
TLS3_k127_6928242_0	1185876.BN8_04108	1.236e-237	742.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_6928242_2	1122605.KB893626_gene2592	4.105e-196	617.0	COG1312@1|root,COG1312@2|Bacteria,4NFA5@976|Bacteroidetes,1IW5I@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the dehydration of D-mannonate	uxuA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0008198,GO:0008927,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019585,GO:0019752,GO:0030145,GO:0032787,GO:0042839,GO:0042840,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0046914,GO:0071704,GO:0072329,GO:1901575	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
TLS3_k127_6928242_3	1279009.ADICEAN_01534	1.114e-88	300.0	COG1496@1|root,COG1496@2|Bacteria,4NM9H@976|Bacteroidetes,47JW0@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the multicopper oxidase YfiH RL5 family	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0046983,GO:0055114	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
TLS3_k127_6928242_1	1121904.ARBP01000004_gene1059	1.467e-198	646.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_6928757_1	525373.HMPREF0766_13075	1.261e-39	151.0	COG1309@1|root,COG1309@2|Bacteria,4NMR8@976|Bacteroidetes,1ISZ6@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
TLS3_k127_6928757_0	1237149.C900_01324	9.382e-64	226.0	COG1028@1|root,COG1028@2|Bacteria,4NQP4@976|Bacteroidetes,47NX2@768503|Cytophagia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_6928757_3	420324.KI911965_gene922	1.005e-11	73.0	COG1280@1|root,COG1280@2|Bacteria,1RAI3@1224|Proteobacteria,2U7PZ@28211|Alphaproteobacteria,1JUI6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
TLS3_k127_6928757_2	485918.Cpin_0603	9.883e-19	88.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IQFY@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_6929170_0	760192.Halhy_6199	7.689e-130	431.0	COG0308@1|root,COG0308@2|Bacteria,4NFTN@976|Bacteroidetes,1INM2@117747|Sphingobacteriia	976|Bacteroidetes	CE	PFAM Peptidase M1 membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
TLS3_k127_6929170_1	1121904.ARBP01000006_gene3887	1.863e-69	250.0	COG4421@1|root,COG4421@2|Bacteria,4NY2Z@976|Bacteroidetes,47SQY@768503|Cytophagia	976|Bacteroidetes	G	Protein of unknown function (DUF563)	-	-	-	-	-	-	-	-	-	-	-	-	DUF563
TLS3_k127_6929267_1	1123276.KB893269_gene4779	1.687e-140	451.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,47JHJ@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase M13	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
TLS3_k127_6929267_4	1237149.C900_01412	7.351e-35	151.0	COG0457@1|root,COG0457@2|Bacteria,4PP7B@976|Bacteroidetes,47WME@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6929267_5	929506.CbC4_1795	4.367e-07	57.0	COG5658@1|root,2ZY3R@2|Bacteria,1VKM4@1239|Firmicutes,25GT4@186801|Clostridia,36V5A@31979|Clostridiaceae	186801|Clostridia	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
TLS3_k127_6929267_0	1123508.JH636442_gene4074	8.785e-147	472.0	COG2055@1|root,COG2055@2|Bacteria,2J36Z@203682|Planctomycetes	203682|Planctomycetes	C	Malate/L-lactate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
TLS3_k127_6929267_2	278957.ABEA03000167_gene2904	3.311e-100	336.0	COG1237@1|root,COG1237@2|Bacteria,46YDX@74201|Verrucomicrobia,3K9DR@414999|Opitutae	414999|Opitutae	S	Beta-lactamase superfamily domain	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
TLS3_k127_6929267_3	1185876.BN8_05387	3.341e-63	220.0	COG0564@1|root,COG0564@2|Bacteria,4NFS8@976|Bacteroidetes,47KV5@768503|Cytophagia	976|Bacteroidetes	J	Pseudouridine synthase	rluC	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
TLS3_k127_6933336_1	1048983.EL17_22575	2.322e-70	242.0	COG1131@1|root,COG1131@2|Bacteria,4NG9T@976|Bacteroidetes,47PAA@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K19340	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC_tran
TLS3_k127_6933336_0	1048983.EL17_22570	1.846e-100	333.0	COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,47KSX@768503|Cytophagia	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_5
TLS3_k127_6933336_2	1239962.C943_00016	1.76e-39	151.0	COG2335@1|root,COG2335@2|Bacteria,4NMPI@976|Bacteroidetes,47XS3@768503|Cytophagia	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
TLS3_k127_6941329_0	925409.KI911562_gene307	9.401e-229	717.0	COG0069@1|root,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,1IREF@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the glutamate synthase family	glt	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
TLS3_k127_6941329_2	794903.OPIT5_11670	1.265e-53	196.0	COG2860@1|root,COG2860@2|Bacteria,46T5E@74201|Verrucomicrobia,3K7YJ@414999|Opitutae	414999|Opitutae	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
TLS3_k127_6941329_1	1123248.KB893317_gene4295	1.516e-132	439.0	COG4775@1|root,COG4775@2|Bacteria,4NF38@976|Bacteroidetes,1IV5H@117747|Sphingobacteriia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6952237_3	153721.MYP_4029	5.673e-84	298.0	COG0457@1|root,COG0457@2|Bacteria,4NIEU@976|Bacteroidetes,47XPU@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
TLS3_k127_6952237_4	929556.Solca_3742	2.26e-75	263.0	COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes,1IRT8@117747|Sphingobacteriia	976|Bacteroidetes	P	ABC-type phosphate transport system periplasmic	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
TLS3_k127_6952237_7	929556.Solca_3744	7.154e-56	205.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,1ISCX@117747|Sphingobacteriia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_6952237_8	1227739.Hsw_0356	3.275e-54	196.0	COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,47Q1Y@768503|Cytophagia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD2	-	-	-	-	-	-	-	-	-	-	-	ExbD
TLS3_k127_6952237_5	926549.KI421517_gene377	2.488e-62	220.0	COG0848@1|root,COG0848@2|Bacteria,4NMT4@976|Bacteroidetes,47NTX@768503|Cytophagia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD1	-	-	-	-	-	-	-	-	-	-	-	ExbD
TLS3_k127_6952237_2	1227739.Hsw_0358	8.652e-95	317.0	COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,47MMA@768503|Cytophagia	976|Bacteroidetes	U	MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
TLS3_k127_6952237_6	1403819.BATR01000007_gene229	4.924e-58	205.0	COG3871@1|root,COG3871@2|Bacteria,46VIW@74201|Verrucomicrobia,2IVPR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Pyridoxamine 5'-phosphate oxidase like	-	-	-	-	-	-	-	-	-	-	-	-	Pyrid_ox_like
TLS3_k127_6952237_9	1396141.BATP01000022_gene487	4.421e-54	196.0	COG0398@1|root,COG0398@2|Bacteria,46Z4H@74201|Verrucomicrobia,2IUX8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
TLS3_k127_6952237_10	1123278.KB893562_gene3254	6.475e-45	166.0	COG1765@1|root,COG1765@2|Bacteria,4P49G@976|Bacteroidetes,47VJ5@768503|Cytophagia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
TLS3_k127_6952237_1	509635.N824_22820	1.167e-96	323.0	COG4912@1|root,COG4912@2|Bacteria,4NKBS@976|Bacteroidetes,1IX96@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
TLS3_k127_6952237_11	1089547.KB913013_gene4734	1.137e-37	145.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,47JBN@768503|Cytophagia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	fucP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
TLS3_k127_6952237_0	926549.KI421517_gene3154	1.407e-136	441.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,47JBN@768503|Cytophagia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	fucP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
TLS3_k127_6962851_0	1122605.KB893648_gene3637	7.96e-191	613.0	COG0464@1|root,COG0464@2|Bacteria,4NJBD@976|Bacteroidetes,1ISED@117747|Sphingobacteriia	976|Bacteroidetes	O	of the AAA class	-	-	-	-	-	-	-	-	-	-	-	-	AAA
TLS3_k127_6962851_1	1121895.Q765_06495	0.0001348	45.0	2C7KB@1|root,32P9G@2|Bacteria,4PA9M@976|Bacteroidetes,1IACU@117743|Flavobacteriia,2NZ0K@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6962907_0	1237149.C900_00804	2.872e-110	361.0	COG0106@1|root,COG0106@2|Bacteria,4NK0E@976|Bacteroidetes,47NT9@768503|Cytophagia	976|Bacteroidetes	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
TLS3_k127_6962907_2	1237149.C900_03498	1.295e-103	355.0	COG2885@1|root,COG2885@2|Bacteria,4NJB2@976|Bacteroidetes,47K81@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_6962907_4	1237149.C900_03497	6.016e-51	186.0	COG0457@1|root,COG0457@2|Bacteria,4NRIH@976|Bacteroidetes,47QEH@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
TLS3_k127_6962907_3	1237149.C900_03494	1.171e-60	214.0	COG1611@1|root,COG1611@2|Bacteria,4NGWU@976|Bacteroidetes,47Q15@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
TLS3_k127_6962907_1	1237149.C900_03492	1.726e-109	367.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,47K87@768503|Cytophagia	976|Bacteroidetes	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
TLS3_k127_6962907_5	1237149.C900_03491	2.692e-29	121.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,GerE,Mor,Response_reg,Y_Y_Y
TLS3_k127_6965923_0	504472.Slin_2974	7.839e-218	693.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,47K58@768503|Cytophagia	976|Bacteroidetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
TLS3_k127_6965923_1	926549.KI421517_gene429	1.776e-61	218.0	COG1082@1|root,COG1082@2|Bacteria,4NIG9@976|Bacteroidetes,47NIT@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_6965936_0	1237149.C900_02381	2.367e-230	721.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,47JJR@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_6965936_2	1237149.C900_02380	2.765e-173	556.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,47KF5@768503|Cytophagia	976|Bacteroidetes	O	PDZ domain (Also known as DHR or GLGF)	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
TLS3_k127_6965936_1	471854.Dfer_1982	2.462e-180	574.0	COG0477@1|root,COG2814@2|Bacteria,4NG6X@976|Bacteroidetes,47KCB@768503|Cytophagia	976|Bacteroidetes	EGP	TIGRFAM Drug resistance transporter Bcr CflA subfamily	bcr	-	-	ko:K03446,ko:K07552	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.2,2.A.1.3	-	-	MFS_1
TLS3_k127_6968570_1	1121904.ARBP01000001_gene5831	7.314e-130	428.0	COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,47JVH@768503|Cytophagia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
TLS3_k127_6968570_2	1237149.C900_02854	1.632e-113	371.0	COG0300@1|root,COG0300@2|Bacteria,4NEMK@976|Bacteroidetes,47JGN@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_6968570_3	153721.MYP_55	1.189e-68	243.0	COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,47MHM@768503|Cytophagia	976|Bacteroidetes	M	Lipid A biosynthesis acyltransferase	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
TLS3_k127_6968570_0	1185876.BN8_00470	1.002e-209	661.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,47JVA@768503|Cytophagia	976|Bacteroidetes	L	PFAM Helicase conserved C-terminal domain	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N
TLS3_k127_6982527_0	1237149.C900_02228	4.908e-206	646.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,47K6I@768503|Cytophagia	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
TLS3_k127_6982527_1	641524.ADICYQ_2547	1.484e-143	471.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,47MUN@768503|Cytophagia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
TLS3_k127_6987431_0	118161.KB235922_gene2360	3.433e-169	552.0	COG1680@1|root,COG1680@2|Bacteria,1G5M7@1117|Cyanobacteria	1117|Cyanobacteria	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
TLS3_k127_6987431_2	1233951.IO90_13550	5.822e-63	223.0	2E2E1@1|root,32XIR@2|Bacteria,4NUDT@976|Bacteroidetes,1IAY1@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6987431_4	688270.Celal_0680	4.139e-15	81.0	2C2CK@1|root,2ZDFY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6987431_1	1121481.AUAS01000005_gene1903	2.302e-126	413.0	COG1082@1|root,COG1082@2|Bacteria,4NFQY@976|Bacteroidetes,47KP7@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_6989915_3	1123276.KB893275_gene2320	2.97e-42	159.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,47M2K@768503|Cytophagia	976|Bacteroidetes	I	PFAM Phosphatidic acid phosphatase type 2 haloperoxidase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
TLS3_k127_6989915_2	643867.Ftrac_0359	9.277e-48	190.0	COG3391@1|root,COG5644@1|root,COG3391@2|Bacteria,COG5644@2|Bacteria,4PMIF@976|Bacteroidetes	976|Bacteroidetes	E	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	HYR,Laminin_G_3
TLS3_k127_6989915_1	1237149.C900_01902	1.183e-66	238.0	COG0226@1|root,COG0226@2|Bacteria,4PKGM@976|Bacteroidetes	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_6989915_0	1237149.C900_01903	2.549e-119	400.0	COG0457@1|root,COG0457@2|Bacteria	1237149.C900_01903|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6992066_3	1168034.FH5T_17405	1.163e-15	77.0	COG2827@1|root,COG2827@2|Bacteria,4P9EH@976|Bacteroidetes,2FZ8T@200643|Bacteroidia	2|Bacteria	L	GIY-YIG catalytic domain	yazA	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
TLS3_k127_6992066_4	1121859.KB890738_gene3625	4.053e-13	75.0	2EEHV@1|root,338BQ@2|Bacteria,4NWH5@976|Bacteroidetes,47SB4@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6992066_2	1237149.C900_04481	1.598e-47	173.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,47QE4@768503|Cytophagia	976|Bacteroidetes	J	TIGRFAM endoribonuclease L-PSP	yjgF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
TLS3_k127_6992066_0	1237149.C900_04480	1.669e-76	263.0	COG1250@1|root,COG1250@2|Bacteria,4NWYY@976|Bacteroidetes,47VDX@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH
TLS3_k127_6992066_1	1124780.ANNU01000052_gene3573	3.707e-51	190.0	COG1283@1|root,COG1283@2|Bacteria,4NMSG@976|Bacteroidetes,47UEZ@768503|Cytophagia	976|Bacteroidetes	P	Na+/Pi-cotransporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_Pi_cotrans
TLS3_k127_6993505_1	1237149.C900_04352	4.947e-146	472.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,47NQ6@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
TLS3_k127_6993505_0	927658.AJUM01000024_gene2518	1.897e-194	615.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,2FMUY@200643|Bacteroidia,3XIQI@558415|Marinilabiliaceae	976|Bacteroidetes	G	MFS/sugar transport protein	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1,MFS_2
TLS3_k127_6993505_2	1237149.C900_04349	2.284e-138	449.0	COG0457@1|root,COG0457@2|Bacteria,4PJN4@976|Bacteroidetes,47NZ0@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6993505_3	700598.Niako_1031	2.073e-83	280.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,1IS23@117747|Sphingobacteriia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
TLS3_k127_6994998_2	1121897.AUGO01000009_gene3046	2.36e-57	204.0	COG3871@1|root,COG3871@2|Bacteria,4NNGC@976|Bacteroidetes,1I1XY@117743|Flavobacteriia,2NWBT@237|Flavobacterium	976|Bacteroidetes	S	general stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyrid_ox_like
TLS3_k127_6994998_3	927658.AJUM01000022_gene1085	1.15e-28	118.0	COG1544@1|root,COG1544@2|Bacteria,4NUWT@976|Bacteroidetes	976|Bacteroidetes	J	ribosomal subunit interface protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
TLS3_k127_6994998_1	1123057.P872_19340	4.184e-130	426.0	COG1537@1|root,COG1537@2|Bacteria,4PPY2@976|Bacteroidetes,47YSP@768503|Cytophagia	976|Bacteroidetes	S	nuclear-transcribed mRNA catabolic process, no-go decay	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6994998_0	866536.Belba_1289	3.169e-217	679.0	2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes,47U5A@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6995532_2	929556.Solca_1011	2.555e-30	122.0	COG0640@1|root,COG0640@2|Bacteria,4NUW3@976|Bacteroidetes,1IZCR@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
TLS3_k127_6995532_0	929556.Solca_1012	1.063e-102	345.0	COG0845@1|root,COG0845@2|Bacteria,4NF3H@976|Bacteroidetes,1ISID@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
TLS3_k127_6995532_1	1121481.AUAS01000006_gene595	5.254e-78	262.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47K8C@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
TLS3_k127_6996864_0	1191523.MROS_2496	0.0	1039.0	COG3661@1|root,COG3661@2|Bacteria	2|Bacteria	G	alpha-glucuronidase activity	aguA	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010383,GO:0010410,GO:0010413,GO:0016052,GO:0016787,GO:0016798,GO:0033939,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044260,GO:0045491,GO:0045493,GO:0071554,GO:0071704,GO:1901575,GO:2000886	3.2.1.139	ko:K01235	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_67C,Glyco_hydro_67M,Glyco_hydro_67N
TLS3_k127_7003430_3	1237149.C900_05562	1.05e-51	188.0	COG0431@1|root,COG0431@2|Bacteria,4NQ3Y@976|Bacteroidetes,47QVB@768503|Cytophagia	976|Bacteroidetes	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
TLS3_k127_7003430_1	1121904.ARBP01000013_gene302	5.399e-147	474.0	COG0665@1|root,COG0665@2|Bacteria,4NEEF@976|Bacteroidetes,47KGT@768503|Cytophagia	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
TLS3_k127_7003430_0	1121904.ARBP01000002_gene7252	1.96e-181	599.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_7003430_5	1121904.ARBP01000004_gene1023	7.225e-39	147.0	COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QWB@768503|Cytophagia	2|Bacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_7003430_6	1408813.AYMG01000028_gene2460	2.322e-23	106.0	2E40F@1|root,32YX9@2|Bacteria,4NV5X@976|Bacteroidetes,1IYTN@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7003430_2	1237149.C900_01563	8.5e-129	441.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_7003430_4	1121904.ARBP01000008_gene3266	1.98e-44	162.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,47KR2@768503|Cytophagia	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
TLS3_k127_7020822_1	1408473.JHXO01000012_gene342	7.556e-119	387.0	COG3325@1|root,COG3325@2|Bacteria,4NGAZ@976|Bacteroidetes,2FNA4@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 18 family	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
TLS3_k127_7020822_0	1237149.C900_02651	3.702e-135	450.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47X9U@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
TLS3_k127_7020822_2	616991.JPOO01000001_gene3481	3.962e-111	363.0	COG1073@1|root,COG1073@2|Bacteria,4NI6C@976|Bacteroidetes,1HYYC@117743|Flavobacteriia	976|Bacteroidetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
TLS3_k127_7025032_2	504472.Slin_2511	2.027e-49	179.0	COG3350@1|root,COG3350@2|Bacteria,4NS9P@976|Bacteroidetes,47Q9E@768503|Cytophagia	976|Bacteroidetes	S	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	YHS
TLS3_k127_7025032_0	1286632.P278_02020	5.776e-233	747.0	COG1629@1|root,COG4771@2|Bacteria,4NEBC@976|Bacteroidetes,1HXBU@117743|Flavobacteriia	976|Bacteroidetes	P	outer membrane protein probably involved in nutrient binding	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_7025032_1	391587.KAOT1_11802	2.983e-69	246.0	COG3712@1|root,COG3712@2|Bacteria,4NH8I@976|Bacteroidetes,1HXP7@117743|Flavobacteriia	976|Bacteroidetes	PT	Fe2 -dicitrate sensor, membrane component	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
TLS3_k127_7036718_1	1123248.KB893321_gene480	5.251e-184	602.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IW4Z@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_7036718_3	471854.Dfer_2509	1.124e-125	428.0	COG1289@1|root,COG1289@2|Bacteria,4NG4J@976|Bacteroidetes,47NEX@768503|Cytophagia	976|Bacteroidetes	S	FUSC-like inner membrane protein yccS	yccS	-	-	-	-	-	-	-	-	-	-	-	FUSC,FUSC-like,FUSC_2
TLS3_k127_7036718_0	1123248.KB893359_gene1998	0.0	1232.0	COG4354@1|root,COG4354@2|Bacteria,4NFQW@976|Bacteroidetes,1IR0K@117747|Sphingobacteriia	976|Bacteroidetes	G	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term	-	-	3.2.1.45	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH116	-	DUF608,Glyco_hydr_116N
TLS3_k127_7036718_4	509635.N824_25365	7.419e-92	313.0	COG0523@1|root,COG0523@2|Bacteria,4P1A4@976|Bacteroidetes,1IW1I@117747|Sphingobacteriia	976|Bacteroidetes	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
TLS3_k127_7036718_5	196162.Noca_3168	5.479e-19	93.0	COG4106@1|root,COG4106@2|Bacteria,2I3M6@201174|Actinobacteria,4DRPX@85009|Propionibacteriales	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_7036718_2	1239962.C943_04256	1.751e-144	466.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,47JP1@768503|Cytophagia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_7038097_0	177439.DP1130	1.239e-118	383.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,42N5W@68525|delta/epsilon subdivisions,2WIU3@28221|Deltaproteobacteria,2MIQ4@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
TLS3_k127_7038097_2	177439.DP1131	5.395e-67	229.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,42QW5@68525|delta/epsilon subdivisions,2WP71@28221|Deltaproteobacteria,2MJKH@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
TLS3_k127_7038097_9	1167006.UWK_02055	2.53e-13	72.0	COG0255@1|root,COG0255@2|Bacteria,1Q1R3@1224|Proteobacteria,42WYX@68525|delta/epsilon subdivisions,2WSTS@28221|Deltaproteobacteria,2MM8K@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
TLS3_k127_7038097_6	177439.DP1133	3.382e-44	161.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,42TNS@68525|delta/epsilon subdivisions,2WR6G@28221|Deltaproteobacteria,2MKWR@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
TLS3_k127_7038097_3	177439.DP1134	2.394e-63	219.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,42RHR@68525|delta/epsilon subdivisions,2WNEK@28221|Deltaproteobacteria,2MJSK@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
TLS3_k127_7038097_4	177439.DP1135	1.535e-55	196.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,42TGC@68525|delta/epsilon subdivisions,2WQ2G@28221|Deltaproteobacteria,2MKGD@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
TLS3_k127_7038097_1	177439.DP1136	4.593e-92	304.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,42QS6@68525|delta/epsilon subdivisions,2WMPD@28221|Deltaproteobacteria,2MJFM@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
TLS3_k127_7038097_8	177439.DP1137	1.47e-30	121.0	COG0199@1|root,COG0199@2|Bacteria,1PDMJ@1224|Proteobacteria,42VCE@68525|delta/epsilon subdivisions,2WR7W@28221|Deltaproteobacteria,2MKUP@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
TLS3_k127_7038097_5	1167006.UWK_02060	1.354e-53	191.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,42SF6@68525|delta/epsilon subdivisions,2WPDP@28221|Deltaproteobacteria,2MJZV@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
TLS3_k127_7038097_7	1167006.UWK_02061	1.201e-38	147.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,42NSE@68525|delta/epsilon subdivisions,2WN9B@28221|Deltaproteobacteria,2MIP4@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
TLS3_k127_7049750_2	331678.Cphamn1_1380	2.379e-09	66.0	COG0457@1|root,COG0457@2|Bacteria	331678.Cphamn1_1380|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7049750_1	929562.Emtol_1742	1.596e-81	280.0	COG0122@1|root,COG0122@2|Bacteria,4NJHK@976|Bacteroidetes,47XRZ@768503|Cytophagia	976|Bacteroidetes	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
TLS3_k127_7049750_0	1237149.C900_03775	4.438e-126	412.0	COG4192@1|root,COG4192@2|Bacteria,4NFY7@976|Bacteroidetes,47MMQ@768503|Cytophagia	976|Bacteroidetes	T	Domain of unknown function (DUF4407)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4407
TLS3_k127_7058178_0	641524.ADICYQ_2266	0.0	1249.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,47KA7@768503|Cytophagia	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
TLS3_k127_7058178_3	1189612.A33Q_4635	2.708e-146	473.0	COG3746@1|root,COG3746@2|Bacteria,4NH24@976|Bacteroidetes,47K0B@768503|Cytophagia	976|Bacteroidetes	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
TLS3_k127_7058178_10	1122621.ATZA01000056_gene4066	2.352e-37	144.0	COG3682@1|root,COG3682@2|Bacteria,4NSQR@976|Bacteroidetes,1ISTV@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional repressor, CopY family	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
TLS3_k127_7058178_8	1121904.ARBP01000009_gene4328	7.915e-57	221.0	COG4219@1|root,COG4219@2|Bacteria,4NKKC@976|Bacteroidetes,47JQV@768503|Cytophagia	976|Bacteroidetes	KT	PFAM Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
TLS3_k127_7058178_4	1121904.ARBP01000006_gene4066	1.337e-138	448.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,47N8Q@768503|Cytophagia	976|Bacteroidetes	M	mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
TLS3_k127_7058178_5	1121904.ARBP01000007_gene3097	1.054e-125	412.0	COG3367@1|root,COG3367@2|Bacteria,4NGXN@976|Bacteroidetes,47NP1@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
TLS3_k127_7058178_2	1239962.C943_00368	3.498e-173	548.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,47KHN@768503|Cytophagia	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
TLS3_k127_7058178_12	762903.Pedsa_1852	2.58e-05	54.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1IQWB@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_7058178_6	1237149.C900_00704	3.856e-116	380.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,47JAM@768503|Cytophagia	976|Bacteroidetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TLS3_k127_7058178_9	1237149.C900_00705	4.424e-50	184.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,47PBZ@768503|Cytophagia	976|Bacteroidetes	S	PFAM Rhomboid family	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
TLS3_k127_7058178_1	1237149.C900_00706	3.768e-261	816.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,47KZU@768503|Cytophagia	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
TLS3_k127_7058178_11	385682.AFSL01000055_gene412	2.722e-07	58.0	2DI87@1|root,302BG@2|Bacteria,4PJBM@976|Bacteroidetes,2G282@200643|Bacteroidia,3XKAK@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7058178_7	762903.Pedsa_2834	2.263e-67	237.0	COG1472@1|root,COG1472@2|Bacteria,4NET8@976|Bacteroidetes,1IP6G@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM glycoside hydrolase family 3	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
TLS3_k127_7058417_0	1239962.C943_00383	9.998e-276	869.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes	976|Bacteroidetes	V	permease	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_7058417_1	1120968.AUBX01000017_gene1883	7.155e-150	482.0	COG0407@1|root,COG0407@2|Bacteria,4NEQ7@976|Bacteroidetes,47K90@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
TLS3_k127_7058417_2	1434325.AZQN01000003_gene2194	4.927e-25	112.0	COG1225@1|root,COG1225@2|Bacteria,4PNAN@976|Bacteroidetes,47SBD@768503|Cytophagia	976|Bacteroidetes	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TLS3_k127_7068813_1	1123248.KB893348_gene332	1.194e-148	477.0	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,1IQEJ@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
TLS3_k127_7068813_0	1237149.C900_04262	1.039e-192	612.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,47MB2@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
TLS3_k127_7068813_3	153721.MYP_3695	1.608e-12	74.0	COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes,47R5X@768503|Cytophagia	976|Bacteroidetes	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7068813_2	1237149.C900_05611	5.265e-52	188.0	COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes,47JSX@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
TLS3_k127_707007_0	1123277.KB893172_gene702	1.962e-296	922.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,COG4654@2|Bacteria,4NDVK@976|Bacteroidetes,47P0X@768503|Cytophagia	976|Bacteroidetes	CG	Carbohydrate binding module (family 6)	-	-	-	ko:K08738,ko:K09992	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	CBM_6,Cytochrom_C,GSDH,PKD,ThuA
TLS3_k127_707007_3	1237149.C900_03418	1.384e-43	170.0	COG3170@1|root,COG3170@2|Bacteria,4PKQP@976|Bacteroidetes,47JDN@768503|Cytophagia	976|Bacteroidetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_707007_2	1237149.C900_03419	4.52e-47	172.0	COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,47R2X@768503|Cytophagia	976|Bacteroidetes	U	Biopolymer transport protein ExbD TolR	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
TLS3_k127_707007_1	1237149.C900_03420	1.142e-94	314.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,47N0M@768503|Cytophagia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
TLS3_k127_707007_4	1237149.C900_03421	6.205e-38	148.0	COG3087@1|root,COG3087@2|Bacteria,4NVU5@976|Bacteroidetes,47S99@768503|Cytophagia	976|Bacteroidetes	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
TLS3_k127_7073608_0	760192.Halhy_1307	5.871e-196	616.0	COG2730@1|root,COG2730@2|Bacteria,4NF3J@976|Bacteroidetes,1IRPS@117747|Sphingobacteriia	976|Bacteroidetes	G	Putative collagen-binding domain of a collagenase	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
TLS3_k127_7073608_1	1237149.C900_02538	9.096e-107	353.0	COG0508@1|root,COG0508@2|Bacteria,4PKNP@976|Bacteroidetes,47MW8@768503|Cytophagia	976|Bacteroidetes	C	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
TLS3_k127_7079259_1	880070.Cycma_1570	5.978e-80	274.0	COG3344@1|root,COG3344@2|Bacteria,4NGGU@976|Bacteroidetes,47QF1@768503|Cytophagia	976|Bacteroidetes	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,HNH,Intron_maturas2,RVT_1,RVT_N
TLS3_k127_7079259_0	980584.AFPB01000171_gene1535	2.05e-136	442.0	COG3335@1|root,COG3335@2|Bacteria,4NT8G@976|Bacteroidetes,1I6Z1@117743|Flavobacteriia	976|Bacteroidetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_32,HTH_33,HTH_Tnp_1
TLS3_k127_7086348_0	616991.JPOO01000001_gene4019	2.09e-148	484.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1HX0V@117743|Flavobacteriia	976|Bacteroidetes	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_7086348_6	1123248.KB893315_gene3246	1.06e-45	169.0	COG4319@1|root,COG4319@2|Bacteria,4NX69@976|Bacteroidetes	976|Bacteroidetes	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7086348_1	504472.Slin_5194	5.596e-108	357.0	COG2367@1|root,COG2367@2|Bacteria,4PMKC@976|Bacteroidetes,47JSP@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
TLS3_k127_7086348_7	1089547.KB913013_gene3762	8.609e-44	176.0	COG1819@1|root,COG1819@2|Bacteria,4NM8M@976|Bacteroidetes,47PKS@768503|Cytophagia	976|Bacteroidetes	CG	glycosyl	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
TLS3_k127_7086348_3	869213.JCM21142_93691	9.16e-67	236.0	COG0730@1|root,COG0730@2|Bacteria,4NKPI@976|Bacteroidetes,47SVW@768503|Cytophagia	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_7086348_2	866536.Belba_3553	9.51e-98	325.0	COG0300@1|root,COG0300@2|Bacteria,4NEMK@976|Bacteroidetes,47Y2N@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_7086348_4	1267211.KI669560_gene2599	7.426e-65	224.0	COG0346@1|root,COG0346@2|Bacteria,4NN6H@976|Bacteroidetes,1IZ3C@117747|Sphingobacteriia	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS3_k127_7086348_5	1237149.C900_02640	1.602e-59	209.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,47Q9G@768503|Cytophagia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
TLS3_k127_7087315_0	1506583.JQJY01000007_gene4109	1.326e-108	361.0	COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,1HZ3N@117743|Flavobacteriia,2NXGC@237|Flavobacterium	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_7087315_1	714943.Mucpa_2377	1.498e-14	77.0	COG0793@1|root,COG0793@2|Bacteria,4NGGJ@976|Bacteroidetes,1ITFP@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
TLS3_k127_709162_2	643867.Ftrac_2681	2.301e-142	460.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,47JGI@768503|Cytophagia	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
TLS3_k127_709162_1	1237149.C900_02366	1.662e-152	489.0	COG0438@1|root,COG0438@2|Bacteria,4NEX8@976|Bacteroidetes,47KFQ@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase 4-like	-	-	-	ko:K13004	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
TLS3_k127_709162_3	1237149.C900_02368	7.968e-73	254.0	COG1596@1|root,COG1596@2|Bacteria,4NPJB@976|Bacteroidetes,47Q04@768503|Cytophagia	976|Bacteroidetes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export
TLS3_k127_709162_0	1237149.C900_02369	2.291e-153	503.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia	976|Bacteroidetes	DM	TIGRFAM capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
TLS3_k127_7097863_9	1237149.C900_05756	3.747e-63	223.0	COG0702@1|root,COG0702@2|Bacteria,4NG89@976|Bacteroidetes,47PTQ@768503|Cytophagia	976|Bacteroidetes	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
TLS3_k127_7097863_18	1237149.C900_05757	7.77e-26	112.0	COG3339@1|root,COG3339@2|Bacteria,4NVFR@976|Bacteroidetes,47RD8@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
TLS3_k127_7097863_11	1237149.C900_05758	5.406e-59	209.0	28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,47M02@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7097863_15	1124780.ANNU01000030_gene1165	4.421e-36	139.0	COG0316@1|root,COG0316@2|Bacteria,4NS6K@976|Bacteroidetes,47R1C@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
TLS3_k127_7097863_16	1237149.C900_00241	4.65e-36	139.0	COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,47QM5@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
TLS3_k127_7097863_10	1237149.C900_00242	7.763e-62	220.0	COG3599@1|root,COG3599@2|Bacteria,4NQDF@976|Bacteroidetes,47QRC@768503|Cytophagia	976|Bacteroidetes	D	TIGRFAM DivIVA domain	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
TLS3_k127_7097863_5	1237149.C900_00243	5.67e-116	386.0	COG2319@1|root,COG2319@2|Bacteria,4NH20@976|Bacteroidetes,47JUN@768503|Cytophagia	976|Bacteroidetes	S	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
TLS3_k127_7097863_12	1124780.ANNU01000030_gene1161	2.037e-42	164.0	COG2091@1|root,COG2091@2|Bacteria,4NSBI@976|Bacteroidetes,47RPQ@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	-	-	-	-	-	-	-	-	-	ACPS
TLS3_k127_7097863_13	1237149.C900_00245	7.588e-41	158.0	COG0526@1|root,COG0526@2|Bacteria,4NSUU@976|Bacteroidetes,47R9W@768503|Cytophagia	976|Bacteroidetes	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
TLS3_k127_7097863_17	762903.Pedsa_2858	6.268e-33	132.0	29AZZ@1|root,2ZXYX@2|Bacteria,4NP6M@976|Bacteroidetes,1ITA8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7097863_8	700598.Niako_2573	7.65e-74	258.0	COG3391@1|root,COG3391@2|Bacteria,4PKC0@976|Bacteroidetes,1J0SQ@117747|Sphingobacteriia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7097863_4	927658.AJUM01000024_gene2500	5.333e-120	398.0	COG4872@1|root,COG4872@2|Bacteria,4NIK7@976|Bacteroidetes	976|Bacteroidetes	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
TLS3_k127_7097863_14	1469557.JSWF01000034_gene836	1.099e-39	154.0	COG4929@1|root,COG4929@2|Bacteria,4NQB4@976|Bacteroidetes,1I3Q6@117743|Flavobacteriia	976|Bacteroidetes	S	GDYXXLXY protein	-	-	-	-	-	-	-	-	-	-	-	-	GDYXXLXY
TLS3_k127_7097863_2	1120965.AUBV01000008_gene1983	1.281e-142	461.0	COG2133@1|root,COG2133@2|Bacteria,4NEZC@976|Bacteroidetes,47KSC@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
TLS3_k127_7097863_1	1237149.C900_05585	1.267e-181	586.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47MW3@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2
TLS3_k127_7097863_3	1237149.C900_01093	3.328e-130	421.0	COG2912@1|root,COG2912@2|Bacteria,4NF8R@976|Bacteroidetes,47JJ3@768503|Cytophagia	976|Bacteroidetes	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
TLS3_k127_7097863_0	1237149.C900_01092	3.05e-302	933.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,47JYJ@768503|Cytophagia	976|Bacteroidetes	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	accD5	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
TLS3_k127_7097863_7	1237149.C900_01090	3.696e-77	269.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,47MMF@768503|Cytophagia	976|Bacteroidetes	Q	Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
TLS3_k127_7097863_6	1237149.C900_01089	1.608e-102	341.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,47M2P@768503|Cytophagia	976|Bacteroidetes	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
TLS3_k127_7098298_0	1121904.ARBP01000004_gene1059	2.648e-197	630.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_7098298_1	929713.NIASO_06610	1.541e-24	108.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS3_k127_712622_0	929562.Emtol_1647	6.049e-112	381.0	COG0179@1|root,COG0179@2|Bacteria,4NFMZ@976|Bacteroidetes,47N4F@768503|Cytophagia	976|Bacteroidetes	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
TLS3_k127_712622_1	376686.Fjoh_0580	1.394e-68	239.0	COG2972@1|root,COG2972@2|Bacteria,4NM0E@976|Bacteroidetes,1I0AJ@117743|Flavobacteriia,2NVBC@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_7129721_5	1123057.P872_00875	2.459e-10	62.0	COG1564@1|root,COG1564@2|Bacteria,4NGJH@976|Bacteroidetes,47MV1@768503|Cytophagia	976|Bacteroidetes	H	thiamine pyrophosphokinase	-	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
TLS3_k127_7129721_2	1313301.AUGC01000011_gene1165	6.281e-79	268.0	COG0463@1|root,COG0463@2|Bacteria,4NGJK@976|Bacteroidetes	976|Bacteroidetes	M	Protein of unknown function (DUF4254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4254
TLS3_k127_7129721_1	1123278.KB893444_gene1676	8.002e-102	343.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,47MA4@768503|Cytophagia	976|Bacteroidetes	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
TLS3_k127_7129721_4	755732.Fluta_2682	1.93e-52	190.0	COG1670@1|root,COG1670@2|Bacteria,4NPQC@976|Bacteroidetes,1I27J@117743|Flavobacteriia,2PBSZ@246874|Cryomorphaceae	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TLS3_k127_7129721_3	468059.AUHA01000002_gene316	4.157e-73	252.0	COG1011@1|root,COG1011@2|Bacteria,4NIMR@976|Bacteroidetes,1IPZN@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
TLS3_k127_7129721_0	269798.CHU_0647	4.387e-196	619.0	COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,47K80@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
TLS3_k127_7137685_2	1124780.ANNU01000036_gene50	6.413e-42	158.0	COG0824@1|root,COG0824@2|Bacteria,4NSIG@976|Bacteroidetes,47S22@768503|Cytophagia	976|Bacteroidetes	S	Acyl-ACP thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
TLS3_k127_7137685_3	243164.DET0292	4.809e-21	106.0	COG5306@1|root,COG5306@2|Bacteria	2|Bacteria	-	-	exbB2	-	-	ko:K03561,ko:K12287	-	-	-	-	ko00000,ko02000,ko02044	1.A.30.2.1	-	-	DUF2341,Laminin_G_3,MotA_ExbB
TLS3_k127_7137685_1	376686.Fjoh_4689	2.612e-43	162.0	COG0764@1|root,COG0764@2|Bacteria,4NUEU@976|Bacteroidetes,1IMZN@117743|Flavobacteriia,2NWQ7@237|Flavobacterium	976|Bacteroidetes	I	dehydratase	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
TLS3_k127_7137685_0	616991.JPOO01000003_gene723	1.547e-215	681.0	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,4NE3J@976|Bacteroidetes,1HXNX@117743|Flavobacteriia,23G9Z@178469|Arenibacter	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
TLS3_k127_7160714_0	1124780.ANNU01000005_gene2370	4.281e-225	703.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,47KAG@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	tuaD	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TLS3_k127_7160714_1	1237149.C900_03511	8.736e-25	104.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,47K4J@768503|Cytophagia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_7161114_1	1313301.AUGC01000003_gene1964	7.782e-63	221.0	COG2850@1|root,COG2850@2|Bacteria,4NEJI@976|Bacteroidetes	976|Bacteroidetes	S	SMART transcription factor jumonji	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
TLS3_k127_7161114_2	649349.Lbys_3467	9.377e-50	185.0	2D3S1@1|root,32TFH@2|Bacteria,4NUIB@976|Bacteroidetes,47VY3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7161114_0	926549.KI421517_gene871	2.671e-104	349.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,47MZQ@768503|Cytophagia	976|Bacteroidetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
TLS3_k127_716136_3	525257.HMPREF0204_13919	1.532e-59	210.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1HZ69@117743|Flavobacteriia,3ZQKD@59732|Chryseobacterium	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
TLS3_k127_716136_0	1237149.C900_03327	1.22e-124	406.0	COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,47M8W@768503|Cytophagia	976|Bacteroidetes	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
TLS3_k127_716136_2	1237149.C900_02502	2.482e-66	238.0	COG0457@1|root,COG0457@2|Bacteria,4NJ1F@976|Bacteroidetes,47NCH@768503|Cytophagia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
TLS3_k127_716136_4	643867.Ftrac_2984	1.103e-45	172.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,47MQZ@768503|Cytophagia	976|Bacteroidetes	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_716136_1	1237149.C900_02073	4.589e-79	268.0	COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,47Q0N@768503|Cytophagia	976|Bacteroidetes	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
TLS3_k127_716136_5	616991.JPOO01000001_gene3504	0.0001088	45.0	COG2197@1|root,COG2197@2|Bacteria,4NM2A@976|Bacteroidetes,1I0B0@117743|Flavobacteriia,23GSU@178469|Arenibacter	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_7168625_0	1237149.C900_02744	2.91e-88	298.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,47M0Q@768503|Cytophagia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_2	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
TLS3_k127_7168625_2	1237149.C900_02742	6.367e-38	146.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,47Q35@768503|Cytophagia	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
TLS3_k127_7168625_1	643867.Ftrac_2605	1.085e-46	186.0	28H89@1|root,2Z7K8@2|Bacteria,4NEKX@976|Bacteroidetes,47M3Y@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7168625_3	880071.Fleli_3381	1.28e-14	73.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,47PQK@768503|Cytophagia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
TLS3_k127_718433_5	471854.Dfer_5567	1.803e-25	110.0	COG1695@1|root,COG1695@2|Bacteria,4NQWD@976|Bacteroidetes,47Y0M@768503|Cytophagia	976|Bacteroidetes	K	Domain of unknown function (DUF4180)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4180
TLS3_k127_718433_0	1121875.KB907547_gene3379	2.088e-198	626.0	COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes,1HZVC@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
TLS3_k127_718433_3	1122226.AUHX01000001_gene615	5.406e-57	210.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,1HWSW@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_718433_1	1239962.C943_01825	4.933e-111	369.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,47PB1@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
TLS3_k127_718433_2	391603.FBALC1_11722	6.296e-82	279.0	COG1416@1|root,COG1416@2|Bacteria,4NH85@976|Bacteroidetes,1I0EY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_718433_4	616991.JPOO01000001_gene3360	2.031e-50	187.0	COG2207@1|root,COG2207@2|Bacteria,4PI6R@976|Bacteroidetes,1IG3A@117743|Flavobacteriia,23IGX@178469|Arenibacter	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_719085_4	1237149.C900_05257	1.033e-11	75.0	29N3N@1|root,33SHJ@2|Bacteria,4P1XQ@976|Bacteroidetes,47TMQ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_719085_1	2340.JV46_09560	4.59e-77	276.0	COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,1S398@1236|Gammaproteobacteria,1J6EW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	P COG0025 NhaP-type Na H and K H antiporters	-	-	-	ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37.1.2	-	-	Na_H_Exchanger
TLS3_k127_719085_0	1120968.AUBX01000018_gene2165	6.468e-109	364.0	COG4775@1|root,COG4775@2|Bacteria,4NF38@976|Bacteroidetes,47KMS@768503|Cytophagia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7197519_0	1121898.Q766_10440	2.483e-252	793.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFBK@976|Bacteroidetes,1HY8A@117743|Flavobacteriia,2NUMJ@237|Flavobacterium	976|Bacteroidetes	EU	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
TLS3_k127_7198665_3	1121007.AUML01000037_gene2004	1.075e-62	220.0	COG1116@1|root,COG1116@2|Bacteria,4NNV0@976|Bacteroidetes,1I89B@117743|Flavobacteriia,2YJA2@290174|Aquimarina	976|Bacteroidetes	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.25	ko:K02045,ko:K02049	ko00920,ko02010,map00920,map02010	M00185,M00188	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran
TLS3_k127_7198665_2	1121007.AUML01000037_gene2005	6.967e-103	340.0	COG0600@1|root,COG0600@2|Bacteria,4NQ8G@976|Bacteroidetes,1I7AE@117743|Flavobacteriia,2YIZC@290174|Aquimarina	976|Bacteroidetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
TLS3_k127_7198665_0	1121007.AUML01000037_gene2006	1.611e-281	875.0	COG2885@1|root,COG2885@2|Bacteria,4NJ85@976|Bacteroidetes,1I8J8@117743|Flavobacteriia,2YI5R@290174|Aquimarina	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
TLS3_k127_7198665_1	1348583.ATLH01000029_gene1668	1.102e-124	409.0	2CJK8@1|root,2ZBWA@2|Bacteria,4NMX2@976|Bacteroidetes,1IJ8E@117743|Flavobacteriia,1F9Z2@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7198665_4	688270.Celal_1651	7.512e-28	121.0	2EMDW@1|root,33F2S@2|Bacteria,4NXUY@976|Bacteroidetes,1IJD1@117743|Flavobacteriia,1FA2N@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_720041_1	1279009.ADICEAN_01112	4.554e-28	114.0	COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,47K2K@768503|Cytophagia	976|Bacteroidetes	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
TLS3_k127_720041_0	29581.BW37_01453	6.373e-321	1008.0	COG0612@1|root,COG0612@2|Bacteria,1Q9S9@1224|Proteobacteria,2WBVP@28216|Betaproteobacteria,476J2@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_720041_2	391596.PBAL39_14239	6.841e-10	62.0	COG5646@1|root,COG5646@2|Bacteria	2|Bacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_7203964_7	1123277.KB893172_gene705	3.599e-51	183.0	COG1595@1|root,COG1595@2|Bacteria,4NRSU@976|Bacteroidetes,47UTH@768503|Cytophagia	976|Bacteroidetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_7203964_5	1123277.KB893172_gene706	4.656e-56	201.0	2CB8F@1|root,34CDS@2|Bacteria,4P8GI@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7203964_0	926549.KI421517_gene2859	4.323e-145	464.0	COG0327@1|root,COG0327@2|Bacteria,4NFJ3@976|Bacteroidetes,47NXF@768503|Cytophagia	976|Bacteroidetes	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
TLS3_k127_7203964_4	761193.Runsl_0300	1.444e-74	254.0	COG2329@1|root,COG2329@2|Bacteria,4NQGS@976|Bacteroidetes,47QSH@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF3291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3291
TLS3_k127_7203964_1	36874.HQ34_02295	1.786e-126	411.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,2FRW8@200643|Bacteroidia,22Z6Z@171551|Porphyromonadaceae	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	bcrA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_7203964_3	111105.HR09_08595	1.296e-100	335.0	COG1277@1|root,COG1277@2|Bacteria,4NN1K@976|Bacteroidetes,2FWQ2@200643|Bacteroidia,22ZHQ@171551|Porphyromonadaceae	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4
TLS3_k127_7203964_2	700598.Niako_3893	2.636e-109	370.0	COG4099@1|root,COG4099@2|Bacteria,4NFSH@976|Bacteroidetes,1IS3G@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,DLH,Esterase,Peptidase_S9
TLS3_k127_7203964_6	1123057.P872_22025	1.083e-54	196.0	COG4815@1|root,COG4815@2|Bacteria,4NQCN@976|Bacteroidetes,47Q5K@768503|Cytophagia	976|Bacteroidetes	S	MepB protein	-	-	-	-	-	-	-	-	-	-	-	-	MepB
TLS3_k127_7204022_2	1237149.C900_01372	4.574e-125	404.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,47KQ7@768503|Cytophagia	976|Bacteroidetes	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
TLS3_k127_7204022_0	1237149.C900_01529	6.776e-271	855.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_7204022_1	761193.Runsl_1970	3.58e-230	736.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_7204022_3	1121904.ARBP01000004_gene1059	2.856e-05	46.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_7211670_3	1123277.KB893191_gene2950	3.727e-11	70.0	COG1169@1|root,COG1169@2|Bacteria,4NF6U@976|Bacteroidetes,47K5Z@768503|Cytophagia	976|Bacteroidetes	HQ	PFAM chorismate binding enzyme	entC	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
TLS3_k127_7211670_2	1279009.ADICEAN_01908	1.313e-57	203.0	COG2050@1|root,COG2050@2|Bacteria,4NNYG@976|Bacteroidetes,47QEZ@768503|Cytophagia	976|Bacteroidetes	Q	PFAM thioesterase superfamily	ydiI	-	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT,Hydrolase_3
TLS3_k127_7211670_0	1237149.C900_04753	1.33e-77	265.0	COG0406@1|root,COG0406@2|Bacteria,4NFX5@976|Bacteroidetes,47JSV@768503|Cytophagia	976|Bacteroidetes	G	phosphoglycerate mutase family	gpm	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
TLS3_k127_7211670_1	1237149.C900_04752	1.82e-76	268.0	COG0457@1|root,COG0457@2|Bacteria,4NG8A@976|Bacteroidetes,47JRE@768503|Cytophagia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7,TPR_8
TLS3_k127_7212281_1	1121889.AUDM01000013_gene1896	9.716e-69	236.0	2CCYF@1|root,2Z9C3@2|Bacteria,4NGNP@976|Bacteroidetes,1I91Q@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7212281_2	1158294.JOMI01000003_gene2265	3.352e-30	128.0	2DEE7@1|root,2ZMKW@2|Bacteria,4P88F@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7212281_0	1120966.AUBU01000002_gene2255	4.279e-173	555.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,4NGX5@976|Bacteroidetes,47KUW@768503|Cytophagia	976|Bacteroidetes	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
TLS3_k127_7214352_0	1121875.KB907550_gene626	3.812e-192	608.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1HYSX@117743|Flavobacteriia	976|Bacteroidetes	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
TLS3_k127_7214352_1	1120965.AUBV01000005_gene1661	7.484e-134	436.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
TLS3_k127_7241934_5	1144313.PMI10_02794	5.044e-09	58.0	COG0308@1|root,COG0308@2|Bacteria,4PHVR@976|Bacteroidetes,1IDIC@117743|Flavobacteriia,2NYI0@237|Flavobacterium	976|Bacteroidetes	M	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
TLS3_k127_7241934_3	1144313.PMI10_02794	3.23e-33	131.0	COG0308@1|root,COG0308@2|Bacteria,4PHVR@976|Bacteroidetes,1IDIC@117743|Flavobacteriia,2NYI0@237|Flavobacterium	976|Bacteroidetes	M	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
TLS3_k127_7241934_2	1218108.KB908294_gene2328	8.604e-42	162.0	COG1396@1|root,COG1396@2|Bacteria,4NHP0@976|Bacteroidetes,1HXUX@117743|Flavobacteriia	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
TLS3_k127_7241934_1	1233951.IO90_02565	1.454e-44	166.0	291R8@1|root,2ZPB9@2|Bacteria,4NPWY@976|Bacteroidetes,1I1XQ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CesT,YbjN
TLS3_k127_7241934_0	1233951.IO90_02560	2.009e-67	236.0	COG1842@1|root,COG1842@2|Bacteria,4NFSJ@976|Bacteroidetes,1HZXN@117743|Flavobacteriia	976|Bacteroidetes	KT	Phage shock protein A (IM30), suppresses sigma54-dependent transcription	pspA	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
TLS3_k127_7241934_4	525373.HMPREF0766_10509	6.053e-27	113.0	28M6W@1|root,2ZAKF@2|Bacteria,4NJT7@976|Bacteroidetes,1IZE3@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1449)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1449
TLS3_k127_7243598_2	1237149.C900_01221	1.171e-09	63.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF,SPOR
TLS3_k127_7243598_1	1237149.C900_01220	8.303e-222	725.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,IgGFc_binding,PKD,Peptidase_M43,fn3
TLS3_k127_7243598_0	1237149.C900_01219	1.095e-264	835.0	COG4932@1|root,COG5644@1|root,COG4932@2|Bacteria,COG5644@2|Bacteria,4NN56@976|Bacteroidetes,47Q8D@768503|Cytophagia	976|Bacteroidetes	M	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS
TLS3_k127_7247947_1	1191523.MROS_0246	1.256e-94	322.0	COG0310@1|root,COG2202@1|root,COG3829@1|root,COG4251@1|root,COG0310@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	cbiM	-	2.7.11.1	ko:K02007,ko:K12132	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_7247947_3	1237149.C900_01499	1.287e-55	199.0	COG0784@1|root,COG0784@2|Bacteria,4PNN1@976|Bacteroidetes,47YBH@768503|Cytophagia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_7247947_0	1237149.C900_01537	1.655e-127	441.0	COG0642@1|root,COG2202@1|root,COG2204@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_7247947_2	865937.Gilli_3441	3.839e-71	246.0	COG2197@1|root,COG2197@2|Bacteria,4NM2A@976|Bacteroidetes,1I0B0@117743|Flavobacteriia	976|Bacteroidetes	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_7247947_4	1458275.AZ34_17610	1.156e-16	85.0	COG2197@1|root,COG2197@2|Bacteria,1NDQC@1224|Proteobacteria,2VVNY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_7249198_4	1347393.HG726020_gene1714	7.12e-30	130.0	COG3279@1|root,COG3279@2|Bacteria,4NU8X@976|Bacteroidetes,2FR3K@200643|Bacteroidia,4APZC@815|Bacteroidaceae	976|Bacteroidetes	KT	COG3279 Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
TLS3_k127_7249198_5	67352.JODS01000052_gene2679	5.899e-05	51.0	COG2234@1|root,COG3227@1|root,COG2234@2|Bacteria,COG3227@2|Bacteria,2GIT0@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase, M28	-	-	3.4.11.24	ko:K19702	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,P_proprotein,Peptidase_M28,Peptidase_M4,Peptidase_M4_C,Peptidase_M6
TLS3_k127_7249198_1	1237149.C900_03855	1.222e-148	481.0	COG2170@1|root,COG2170@2|Bacteria,4NGA3@976|Bacteroidetes	976|Bacteroidetes	S	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
TLS3_k127_7249198_0	1237149.C900_03854	3.55e-174	558.0	COG0189@1|root,COG0189@2|Bacteria,4NF2R@976|Bacteroidetes,47P1C@768503|Cytophagia	976|Bacteroidetes	HJ	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
TLS3_k127_7249198_2	1121440.AUMA01000020_gene1968	2.246e-77	266.0	COG3271@1|root,COG3271@2|Bacteria,1RAD5@1224|Proteobacteria,42QWA@68525|delta/epsilon subdivisions,2WMVM@28221|Deltaproteobacteria,2M8RA@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39,Peptidase_C39_2
TLS3_k127_7249198_3	1237149.C900_03851	1.787e-54	199.0	COG1723@1|root,COG1723@2|Bacteria,4NFED@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
TLS3_k127_7249389_3	153721.MYP_2837	9.719e-56	196.0	COG3832@1|root,COG3832@2|Bacteria,4PKNU@976|Bacteroidetes,47QK4@768503|Cytophagia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_7249389_1	1123276.KB893245_gene953	1.96e-71	247.0	COG0705@1|root,COG0705@2|Bacteria,4NECA@976|Bacteroidetes,47N8U@768503|Cytophagia	976|Bacteroidetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TLS3_k127_7249389_5	794903.OPIT5_11735	8.813e-44	169.0	COG0500@1|root,COG0500@2|Bacteria,46V7N@74201|Verrucomicrobia,3K8BC@414999|Opitutae	414999|Opitutae	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_7249389_6	929556.Solca_2792	1.001e-30	121.0	COG4628@1|root,COG4628@2|Bacteria,4NUS1@976|Bacteroidetes,1ITZK@117747|Sphingobacteriia	976|Bacteroidetes	S	DNA-binding protein VF530	-	-	-	-	-	-	-	-	-	-	-	-	VF530
TLS3_k127_7249389_4	929556.Solca_4221	4.587e-52	188.0	2APQJ@1|root,31EUD@2|Bacteria,4NNU5@976|Bacteroidetes,1ITJ4@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7249389_0	1408433.JHXV01000005_gene2538	5.996e-129	419.0	COG2070@1|root,COG2070@2|Bacteria,4NFIW@976|Bacteroidetes,1HY76@117743|Flavobacteriia,2PBER@246874|Cryomorphaceae	976|Bacteroidetes	S	Thiazole biosynthesis protein ThiG	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
TLS3_k127_7249389_2	1434325.AZQN01000009_gene3994	3.488e-65	230.0	COG2962@1|root,COG2962@2|Bacteria,4NPB9@976|Bacteroidetes,47P6W@768503|Cytophagia	976|Bacteroidetes	S	EamA-like transporter family	yojE	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
TLS3_k127_7254304_1	1469557.JSWF01000040_gene3061	1.234e-78	271.0	COG1073@1|root,COG1073@2|Bacteria,4NJGA@976|Bacteroidetes,1I14X@117743|Flavobacteriia	976|Bacteroidetes	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	BAAT_C
TLS3_k127_7254304_2	575590.HMPREF0156_00475	0.0004794	53.0	COG4886@1|root,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes	976|Bacteroidetes	DZ	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4
TLS3_k127_7254304_0	927658.AJUM01000024_gene2621	2.302e-127	437.0	COG3386@1|root,COG3386@2|Bacteria,4NK33@976|Bacteroidetes	976|Bacteroidetes	G	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_725441_1	1185876.BN8_00340	2.492e-142	464.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,47M2K@768503|Cytophagia	976|Bacteroidetes	I	PFAM Phosphatidic acid phosphatase type 2 haloperoxidase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
TLS3_k127_725441_4	313606.M23134_05906	3.796e-10	70.0	COG1404@1|root,COG4447@1|root,COG4733@1|root,COG4935@1|root,COG5184@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,COG5184@2|Bacteria,4NEJ8@976|Bacteroidetes,47N4Z@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	MAM,TIG,fn3
TLS3_k127_725441_0	866536.Belba_3618	0.0	1116.0	COG4206@1|root,COG4206@2|Bacteria,4PKNV@976|Bacteroidetes,47XXQ@768503|Cytophagia	976|Bacteroidetes	H	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
TLS3_k127_725441_2	269798.CHU_2068	1.038e-71	246.0	COG4572@1|root,COG4572@2|Bacteria,4PM1W@976|Bacteroidetes,47XZW@768503|Cytophagia	976|Bacteroidetes	S	Cation transport regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_725441_3	926556.Echvi_0557	2.116e-37	147.0	COG0071@1|root,COG0071@2|Bacteria,4NSJB@976|Bacteroidetes,47R4W@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
TLS3_k127_7263821_2	504472.Slin_4428	6.401e-82	276.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,47JJ6@768503|Cytophagia	976|Bacteroidetes	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
TLS3_k127_7263821_4	1237149.C900_02237	3.848e-34	135.0	2ADW0@1|root,313N0@2|Bacteria,4NSUW@976|Bacteroidetes,47R7E@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7263821_0	1237149.C900_02236	4.874e-294	917.0	COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,47K6U@768503|Cytophagia	976|Bacteroidetes	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
TLS3_k127_7263821_1	1237149.C900_02235	2.755e-223	700.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,47JT3@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_7263821_3	1237149.C900_02234	2.512e-35	135.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,47KEP@768503|Cytophagia	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
TLS3_k127_7275317_3	1237149.C900_01409	1.721e-39	151.0	COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,47M2T@768503|Cytophagia	976|Bacteroidetes	LU	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
TLS3_k127_7275317_1	1237149.C900_01380	7.062e-85	286.0	COG0457@1|root,COG0457@2|Bacteria,4NUXH@976|Bacteroidetes,47XIV@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_8
TLS3_k127_7275317_0	1237149.C900_01378	1.132e-108	359.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,47KB5@768503|Cytophagia	976|Bacteroidetes	E	Isopropylmalate homocitrate citramalate synthase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
TLS3_k127_7275317_2	1237149.C900_01377	1.824e-46	170.0	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,47NYP@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
TLS3_k127_7281354_2	153721.MYP_4730	2.053e-40	152.0	COG2315@1|root,COG2315@2|Bacteria,4NS6J@976|Bacteroidetes,47R6I@768503|Cytophagia	976|Bacteroidetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
TLS3_k127_7281354_1	641524.ADICYQ_3512	2.599e-71	248.0	COG2135@1|root,COG2135@2|Bacteria,4NI3T@976|Bacteroidetes,47XPZ@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the SOS response-associated peptidase family	yoqW	-	-	-	-	-	-	-	-	-	-	-	SRAP
TLS3_k127_7281354_0	1237149.C900_00609	9.678e-124	403.0	COG0429@1|root,COG0429@2|Bacteria,4NFGZ@976|Bacteroidetes,47JJP@768503|Cytophagia	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
TLS3_k127_7284412_2	1408473.JHXO01000005_gene1721	3.467e-61	214.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,2FNNY@200643|Bacteroidia	976|Bacteroidetes	S	Transporter gate domain protein	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
TLS3_k127_7284412_1	1237149.C900_01575	2.562e-83	277.0	2C4H4@1|root,32CX0@2|Bacteria,4NRZ7@976|Bacteroidetes,47SG5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7284412_3	1237149.C900_01572	6.948e-41	161.0	COG0526@1|root,COG0526@2|Bacteria,4NI00@976|Bacteroidetes,47QR6@768503|Cytophagia	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
TLS3_k127_7287003_1	1237149.C900_01000	1.696e-72	251.0	COG0308@1|root,COG0308@2|Bacteria,4PNPR@976|Bacteroidetes,47YF9@768503|Cytophagia	976|Bacteroidetes	E	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_7287003_2	1123278.KB893481_gene3487	9.665e-57	207.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,47TVA@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,TPR_12,TPR_7,TPR_8,Y_Y_Y
TLS3_k127_7287003_0	1237149.C900_00995	2.215e-193	610.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,47JJH@768503|Cytophagia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_7287003_3	504472.Slin_1600	9.301e-55	194.0	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,47JZK@768503|Cytophagia	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
TLS3_k127_7287732_0	1237149.C900_00754	3.504e-223	698.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,47JN6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_7287732_1	1237149.C900_04519	6.982e-42	155.0	COG1533@1|root,COG1533@2|Bacteria,4NE62@976|Bacteroidetes,47M4W@768503|Cytophagia	976|Bacteroidetes	L	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TLS3_k127_7290282_1	313598.MED152_05080	1.134e-14	74.0	COG0524@1|root,COG0524@2|Bacteria,4NH9X@976|Bacteroidetes,1HYAW@117743|Flavobacteriia,3VX2N@52959|Polaribacter	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
TLS3_k127_7290282_0	1270196.JCKI01000009_gene3386	6.585e-87	298.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1IY37@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
TLS3_k127_7294076_0	525373.HMPREF0766_13078	4.18e-225	708.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPQ1@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS3_k127_7294076_1	525373.HMPREF0766_13077	7.419e-100	336.0	COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes,1IS62@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS3_k127_7297331_0	1121904.ARBP01000004_gene1059	3.476e-184	604.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_7297331_1	1117314.PCIT_22639	8.879e-62	219.0	COG0451@1|root,COG0451@2|Bacteria,1QP8J@1224|Proteobacteria,1RP88@1236|Gammaproteobacteria,2Q1EY@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	GM	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
TLS3_k127_7300623_2	761193.Runsl_2562	1.026e-41	158.0	COG1943@1|root,COG1943@2|Bacteria,4NNFK@976|Bacteroidetes,47PUJ@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
TLS3_k127_7300623_4	1121957.ATVL01000010_gene255	4.936e-22	101.0	COG2146@1|root,COG2146@2|Bacteria,4NV1B@976|Bacteroidetes,47S5J@768503|Cytophagia	976|Bacteroidetes	P	nitrite reductase [NAD(P)H] activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7300623_1	1237149.C900_03120	9.876e-101	335.0	COG1250@1|root,COG1250@2|Bacteria,4NF2W@976|Bacteroidetes,47XHJ@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
TLS3_k127_7300623_0	643867.Ftrac_2390	6.987e-149	479.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,47JM1@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
TLS3_k127_7300623_3	1237149.C900_03113	1.254e-34	135.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,47M4P@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
TLS3_k127_7307914_0	926556.Echvi_1901	1.729e-182	574.0	COG1251@1|root,COG1251@2|Bacteria,4NE44@976|Bacteroidetes,47M7X@768503|Cytophagia	976|Bacteroidetes	C	Nitrite and sulphite reductase 4Fe-4S	-	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
TLS3_k127_7307914_2	1121859.KB890739_gene2206	3.164e-56	198.0	COG2146@1|root,COG2146@2|Bacteria,4NQQ8@976|Bacteroidetes,47QJ5@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM nitrite reductase NAD(P)H , small subunit	-	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske_2
TLS3_k127_7307914_3	616991.JPOO01000003_gene54	1.073e-36	140.0	2DCU1@1|root,32U0B@2|Bacteria,4NV6G@976|Bacteroidetes,1I5R4@117743|Flavobacteriia	976|Bacteroidetes	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
TLS3_k127_7307914_1	1121904.ARBP01000009_gene4294	1.241e-143	468.0	COG0155@1|root,COG1773@1|root,COG0155@2|Bacteria,COG1773@2|Bacteria,4NHF0@976|Bacteroidetes,47M86@768503|Cytophagia	976|Bacteroidetes	C	Rubredoxin	rubR	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
TLS3_k127_7313180_3	1356852.N008_00765	2.665e-103	349.0	COG4206@1|root,COG4206@2|Bacteria,4PKNV@976|Bacteroidetes,47XXQ@768503|Cytophagia	976|Bacteroidetes	H	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
TLS3_k127_7313180_7	1120966.AUBU01000010_gene2870	2.539e-14	85.0	COG1228@1|root,COG1228@2|Bacteria,4NHGA@976|Bacteroidetes,47N43@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
TLS3_k127_7313180_2	1237149.C900_04118	9.824e-112	365.0	COG3142@1|root,COG3142@2|Bacteria,4NINY@976|Bacteroidetes,47NRE@768503|Cytophagia	976|Bacteroidetes	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
TLS3_k127_7313180_1	1453498.LG45_01110	9.567e-145	466.0	COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,1HXFB@117743|Flavobacteriia,2NTK7@237|Flavobacterium	976|Bacteroidetes	E	Asparaginase	aspG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
TLS3_k127_7313180_5	643867.Ftrac_2275	4.479e-49	180.0	COG0791@1|root,COG0791@2|Bacteria,4NSZJ@976|Bacteroidetes,47PEH@768503|Cytophagia	976|Bacteroidetes	M	Cell wall-associated hydrolase (invasion-associated protein)	spr	-	-	ko:K13695	-	-	-	-	ko00000,ko01002	-	-	-	LysM,NLPC_P60
TLS3_k127_7313180_4	1185876.BN8_05092	1.504e-70	250.0	COG1957@1|root,COG1957@2|Bacteria,4NH09@976|Bacteroidetes,47JEE@768503|Cytophagia	976|Bacteroidetes	F	Inosine-uridine preferring nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
TLS3_k127_7313180_0	1121373.KB903629_gene331	5.242e-213	671.0	COG3046@1|root,COG3046@2|Bacteria,4NECD@976|Bacteroidetes,47N6N@768503|Cytophagia	976|Bacteroidetes	S	Deoxyribodipyrimidine photo-lyase-related protein	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP,FAD_binding_7
TLS3_k127_7313180_6	313624.NSP_28770	7.842e-17	80.0	COG4338@1|root,COG4338@2|Bacteria,1G94B@1117|Cyanobacteria,1HQ19@1161|Nostocales	1117|Cyanobacteria	S	protein conserved in bacteria (DUF2256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2256
TLS3_k127_7313180_8	391625.PPSIR1_39605	1.163e-12	68.0	COG0204@1|root,COG1022@1|root,COG3320@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,COG3320@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria,2YU6Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Male sterility protein	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
TLS3_k127_7313765_1	1124780.ANNU01000023_gene3187	1.085e-75	256.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,47JYW@768503|Cytophagia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
TLS3_k127_7313765_2	643867.Ftrac_0860	1.961e-40	151.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,47QCW@768503|Cytophagia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
TLS3_k127_7313765_3	883126.HMPREF9710_04417	2.507e-05	46.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2VIWI@28216|Betaproteobacteria,475VM@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
TLS3_k127_7313765_0	1124780.ANNU01000080_gene2581	9.183e-182	576.0	COG3328@1|root,COG3328@2|Bacteria,4NFQS@976|Bacteroidetes,47JYB@768503|Cytophagia	976|Bacteroidetes	L	PFAM Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
TLS3_k127_7313765_4	1237149.C900_04796	7.233e-05	49.0	COG0848@1|root,COG0848@2|Bacteria,4NKT1@976|Bacteroidetes,47PP4@768503|Cytophagia	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
TLS3_k127_7315308_0	247490.KSU1_D0082	6.875e-99	338.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	wzx	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
TLS3_k127_7315308_3	1123277.KB893244_gene5123	5.495e-13	71.0	COG0673@1|root,COG0673@2|Bacteria,4PITU@976|Bacteroidetes,47KDG@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_7315308_1	1048983.EL17_11190	1.252e-96	319.0	COG0110@1|root,COG0110@2|Bacteria,4NENC@976|Bacteroidetes,47NXE@768503|Cytophagia	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
TLS3_k127_7315308_2	1124780.ANNU01000005_gene2419	4.692e-90	300.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,47KX7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_732014_5	1237149.C900_05169	8.937e-65	230.0	COG3548@1|root,COG3548@2|Bacteria,4NW8Z@976|Bacteroidetes,47V92@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
TLS3_k127_732014_4	313598.MED152_12649	6.334e-68	238.0	COG2339@1|root,COG2339@2|Bacteria,4NGUS@976|Bacteroidetes,1HY3J@117743|Flavobacteriia,3VVQ8@52959|Polaribacter	976|Bacteroidetes	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
TLS3_k127_732014_2	1237149.C900_00826	5.711e-78	264.0	2DZGZ@1|root,32VAD@2|Bacteria,4NSFP@976|Bacteroidetes,47RS7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_10
TLS3_k127_732014_3	1124780.ANNU01000006_gene2845	3.243e-74	254.0	COG0778@1|root,COG0778@2|Bacteria,4NMUE@976|Bacteroidetes,47PFV@768503|Cytophagia	976|Bacteroidetes	C	Nitroreductase family	ydjA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
TLS3_k127_732014_8	525373.HMPREF0766_11971	8.042e-13	78.0	2C2QD@1|root,2ZW7X@2|Bacteria,4NPHF@976|Bacteroidetes,1ISNA@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_732014_0	1237149.C900_03169	1.047e-174	554.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,47MDV@768503|Cytophagia	976|Bacteroidetes	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
TLS3_k127_732014_1	1237149.C900_03167	4.084e-129	422.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,47JWQ@768503|Cytophagia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
TLS3_k127_732014_6	1124780.ANNU01000078_gene760	8.42e-38	147.0	COG1714@1|root,COG1714@2|Bacteria,4NW7J@976|Bacteroidetes,47X24@768503|Cytophagia	976|Bacteroidetes	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
TLS3_k127_732014_7	1356852.N008_19955	6.226e-16	83.0	2DNSC@1|root,32YWT@2|Bacteria,4NVHW@976|Bacteroidetes,47VS9@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_7340345_5	1313301.AUGC01000001_gene1406	6.489e-08	53.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes	976|Bacteroidetes	E	decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS3_k127_7340345_2	1237149.C900_00273	1.263e-127	416.0	COG0010@1|root,COG0010@2|Bacteria,4NE26@976|Bacteroidetes,47N30@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the arginase family	rocF	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS3_k127_7340345_3	1122605.KB893625_gene2027	5.245e-24	109.0	2EU2T@1|root,33MJR@2|Bacteria,4NZIZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7340345_1	762903.Pedsa_2629	3.134e-182	574.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1IPCP@117747|Sphingobacteriia	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
TLS3_k127_7340345_0	1237149.C900_00279	3.899e-267	833.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,47K91@768503|Cytophagia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
TLS3_k127_7340345_4	1197477.IA57_10265	1.015e-15	78.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,1I1AR@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
TLS3_k127_7346060_1	1237149.C900_05787	7.165e-86	291.0	COG0577@1|root,COG0577@2|Bacteria,4P1B0@976|Bacteroidetes,47U89@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	MacB_PCD
TLS3_k127_7346060_0	1123248.KB893329_gene4456	1.958e-160	516.0	COG0500@1|root,COG0500@2|Bacteria,4PPPH@976|Bacteroidetes,1IW2X@117747|Sphingobacteriia	976|Bacteroidetes	Q	C-methyltransferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
TLS3_k127_7346060_2	743722.Sph21_1178	2.094e-66	235.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IW4Z@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_7356484_1	866536.Belba_1550	9.16e-17	83.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47M5P@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
TLS3_k127_7356484_0	1237149.C900_01776	0.0	1457.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,47K29@768503|Cytophagia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
TLS3_k127_7371636_3	1235811.HMPREF0653_00332	1.009e-27	124.0	COG2207@1|root,COG2207@2|Bacteria,4NEEQ@976|Bacteroidetes	976|Bacteroidetes	K	transcriptional regulator (AraC family)	pchR	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_7371636_1	1123276.KB893252_gene3675	4.302e-46	174.0	28ME7@1|root,2ZARX@2|Bacteria,4P47D@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
TLS3_k127_7371636_0	761193.Runsl_5484	0.0	1106.0	COG3511@1|root,COG3511@2|Bacteria,4NHDA@976|Bacteroidetes,47KEM@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM phospholipase C, phosphocholine-specific	plcN	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	DUF756,Phosphoesterase
TLS3_k127_7371636_2	700598.Niako_0267	1.141e-33	133.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,1IQUD@117747|Sphingobacteriia	976|Bacteroidetes	M	AsmA family	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
TLS3_k127_7383422_4	411476.BACOVA_02470	2.185e-61	216.0	COG0451@1|root,COG0451@2|Bacteria,4PHT4@976|Bacteroidetes,2FNQG@200643|Bacteroidia,4APQW@815|Bacteroidaceae	976|Bacteroidetes	M	COG0451 Nucleoside-diphosphate-sugar	-	-	5.1.3.26	ko:K19997	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
TLS3_k127_7383422_3	216432.CA2559_02945	1.504e-73	251.0	COG0110@1|root,COG0110@2|Bacteria,4NMZ2@976|Bacteroidetes,1I1H0@117743|Flavobacteriia	976|Bacteroidetes	S	acetyltransferase, isoleucine patch superfamily	wcaF	-	-	ko:K03818	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
TLS3_k127_7383422_0	504472.Slin_6297	1.078e-157	506.0	COG0438@1|root,COG0438@2|Bacteria,4NI3I@976|Bacteroidetes,47MKE@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_7383422_1	714943.Mucpa_4370	9.26e-145	468.0	COG0438@1|root,COG0438@2|Bacteria,4NJQU@976|Bacteroidetes,1IPJM@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_7383422_2	1150600.ADIARSV_4000	7.973e-134	435.0	COG4641@1|root,COG4641@2|Bacteria,4NX3U@976|Bacteroidetes,1IVFG@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
TLS3_k127_7383422_5	1150600.ADIARSV_3999	2.818e-12	69.0	2ADQ2@1|root,313F9@2|Bacteria,4NI26@976|Bacteroidetes,1IWNY@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7383781_0	616991.JPOO01000003_gene1398	7.441e-241	749.0	COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,1I886@117743|Flavobacteriia,23FTQ@178469|Arenibacter	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_7383781_4	641524.ADICYQ_3136	0.0001134	46.0	COG5499@1|root,COG5499@2|Bacteria,4NNXF@976|Bacteroidetes,47QMJ@768503|Cytophagia	976|Bacteroidetes	K	transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
TLS3_k127_7383781_1	1313421.JHBV01000041_gene3398	6.62e-130	437.0	COG4206@1|root,COG4206@2|Bacteria,4NIJS@976|Bacteroidetes	976|Bacteroidetes	H	COG4206 Outer membrane cobalamin receptor protein	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_7384202_4	388413.ALPR1_00725	4.688e-15	77.0	COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47JB2@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
TLS3_k127_7384202_1	1237149.C900_03225	1.242e-35	138.0	2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,47RVQ@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4286)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4286
TLS3_k127_7384202_0	866536.Belba_0607	3.211e-72	247.0	COG0454@1|root,COG0456@2|Bacteria,4NNJS@976|Bacteroidetes,47PUS@768503|Cytophagia	976|Bacteroidetes	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_7384202_3	1279009.ADICEAN_02930	3.754e-26	117.0	COG0662@1|root,COG0662@2|Bacteria,4NSGT@976|Bacteroidetes,47RN2@768503|Cytophagia	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_7384202_2	1189612.A33Q_1398	4.346e-30	132.0	COG2207@1|root,COG2207@2|Bacteria,4NEEQ@976|Bacteroidetes,47RA1@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	pchR	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_7387604_6	925409.KI911562_gene804	7.144e-14	72.0	COG1045@1|root,COG1045@2|Bacteria,4NGZ7@976|Bacteroidetes,1IPAM@117747|Sphingobacteriia	976|Bacteroidetes	E	Serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
TLS3_k127_7387604_5	269798.CHU_3028	5.226e-26	113.0	COG3437@1|root,COG3437@2|Bacteria,4PKM8@976|Bacteroidetes,47XWF@768503|Cytophagia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_7387604_1	1237149.C900_05257	6.665e-109	360.0	29N3N@1|root,33SHJ@2|Bacteria,4P1XQ@976|Bacteroidetes,47TMQ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7387604_0	1237149.C900_05256	0.0	1275.0	COG1131@1|root,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,47KQD@768503|Cytophagia	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,TerB
TLS3_k127_7387604_3	1124780.ANNU01000020_gene3294	5.543e-68	239.0	COG1434@1|root,COG1434@2|Bacteria,4NNYV@976|Bacteroidetes,47PRX@768503|Cytophagia	976|Bacteroidetes	S	PFAM DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
TLS3_k127_7387604_4	1122179.KB890491_gene4372	1.3e-26	113.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes	976|Bacteroidetes	P	COG0607 Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS3_k127_7387604_2	1237149.C900_01184	6.748e-72	260.0	COG2755@1|root,COG2755@2|Bacteria,4NGTK@976|Bacteroidetes,47NWX@768503|Cytophagia	976|Bacteroidetes	E	GDSL family lipolytic protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
TLS3_k127_7390836_1	1237149.C900_04537	1.725e-91	309.0	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,47JQR@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
TLS3_k127_7390836_0	1279009.ADICEAN_01245	4.097e-100	332.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,47KW6@768503|Cytophagia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
TLS3_k127_7390836_2	1237149.C900_05167	4.212e-63	220.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,47N7G@768503|Cytophagia	976|Bacteroidetes	O	Gliding motility protein, GldB	gldB	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7407864_1	1185876.BN8_06647	8.229e-101	344.0	COG3356@1|root,COG3356@2|Bacteria,4NGDG@976|Bacteroidetes,47JVE@768503|Cytophagia	976|Bacteroidetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
TLS3_k127_7407864_3	290315.Clim_1380	2.774e-35	139.0	COG1525@1|root,COG1525@2|Bacteria	2|Bacteria	L	nuclease	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
TLS3_k127_7407864_0	1406840.Q763_16325	0.0	1873.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1HX21@117743|Flavobacteriia,2NSGS@237|Flavobacterium	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
TLS3_k127_7407864_2	1237149.C900_00541	4.183e-77	267.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,47PIA@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_7407864_5	485913.Krac_4632	5.563e-12	76.0	COG0457@1|root,COG0457@2|Bacteria	485913.Krac_4632|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7407864_4	873517.HMPREF1977_1011	9.65e-19	86.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1HY43@117743|Flavobacteriia,1EQGA@1016|Capnocytophaga	976|Bacteroidetes	T	gtp-binding protein typa	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
TLS3_k127_7413551_2	700598.Niako_0719	3.729e-17	93.0	COG2755@1|root,COG2755@2|Bacteria,4NPB3@976|Bacteroidetes,1IWDM@117747|Sphingobacteriia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS3_k127_7413551_1	929713.NIASO_15340	4.793e-88	302.0	COG0584@1|root,COG0584@2|Bacteria,4NGI1@976|Bacteroidetes	976|Bacteroidetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	FlgD_ig,GDPD,Phytase-like
TLS3_k127_7413551_0	1122605.KB893635_gene3512	1.6e-119	386.0	COG0554@1|root,COG0554@2|Bacteria,4NFUH@976|Bacteroidetes,1IP31@117747|Sphingobacteriia	976|Bacteroidetes	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
TLS3_k127_7422541_3	1121904.ARBP01000012_gene1305	1.857e-34	136.0	COG0438@1|root,COG0438@2|Bacteria,4NIP2@976|Bacteroidetes,47MWD@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_7422541_0	1237149.C900_02440	9.137e-152	507.0	COG4625@1|root,COG4625@2|Bacteria,4NJDV@976|Bacteroidetes,47NUN@768503|Cytophagia	976|Bacteroidetes	E	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin,NPCBM,PA14,RicinB_lectin_2
TLS3_k127_7422541_1	1121904.ARBP01000006_gene3886	2.453e-93	313.0	COG1922@1|root,COG1922@2|Bacteria,4NJGT@976|Bacteroidetes,47NEK@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the glycosyltransferase 26 family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
TLS3_k127_7422541_2	1121904.ARBP01000006_gene3883	9.622e-91	301.0	COG2148@1|root,COG2148@2|Bacteria,4NER4@976|Bacteroidetes,47N5W@768503|Cytophagia	976|Bacteroidetes	M	sugar transferase	wcaJ_2	-	2.7.8.6	ko:K00996,ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
TLS3_k127_7427913_1	1121859.KB890738_gene3176	4.028e-88	294.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,47JA6@768503|Cytophagia	976|Bacteroidetes	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
TLS3_k127_7427913_0	1237149.C900_01034	4.826e-180	589.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,47M4V@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
TLS3_k127_7427913_2	1237149.C900_01035	1.365e-26	111.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,47K9Z@768503|Cytophagia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
TLS3_k127_7439415_6	1237149.C900_02205	1.124e-20	94.0	29SSC@1|root,30DYA@2|Bacteria,4NM51@976|Bacteroidetes,47PSA@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3822)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3822
TLS3_k127_7439415_2	1237149.C900_02204	3.787e-56	206.0	2C0G9@1|root,310GM@2|Bacteria,4NHU0@976|Bacteroidetes,47NP8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7439415_4	761193.Runsl_3776	3.659e-39	152.0	COG1051@1|root,COG1051@2|Bacteria,4NN73@976|Bacteroidetes,47P7Y@768503|Cytophagia	976|Bacteroidetes	F	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
TLS3_k127_7439415_3	1237149.C900_02200	1.653e-40	153.0	COG2885@1|root,COG2885@2|Bacteria,4NRQ3@976|Bacteroidetes,47S5T@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
TLS3_k127_7439415_5	1185876.BN8_04757	3.507e-33	132.0	COG2363@1|root,COG2363@2|Bacteria,4NS8F@976|Bacteroidetes,47RJW@768503|Cytophagia	976|Bacteroidetes	S	small membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
TLS3_k127_7439415_1	1237149.C900_02196	5.787e-88	295.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,47M4Y@768503|Cytophagia	976|Bacteroidetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
TLS3_k127_7439415_0	1237149.C900_02195	1.23e-99	328.0	COG0318@1|root,COG0318@2|Bacteria,4PKQG@976|Bacteroidetes,47K42@768503|Cytophagia	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
TLS3_k127_7447879_2	697282.Mettu_0542	1.68e-05	47.0	COG3861@1|root,COG3861@2|Bacteria,1RD6Y@1224|Proteobacteria,1S4FS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PRC
TLS3_k127_7447879_1	697282.Mettu_0542	5.976e-112	366.0	COG3861@1|root,COG3861@2|Bacteria,1RD6Y@1224|Proteobacteria,1S4FS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PRC
TLS3_k127_7447879_0	1499967.BAYZ01000036_gene2443	1.513e-267	829.0	COG3957@1|root,COG3957@2|Bacteria,2NRD9@2323|unclassified Bacteria	2|Bacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
TLS3_k127_745797_2	485917.Phep_0089	9.203e-128	414.0	COG0647@1|root,COG0647@2|Bacteria,4NG49@976|Bacteroidetes,1IRQX@117747|Sphingobacteriia	976|Bacteroidetes	G	Haloacid Dehalogenase Superfamily Class (subfamily) IIA	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
TLS3_k127_745797_0	649349.Lbys_2944	8.44e-261	813.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,47KIN@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
TLS3_k127_745797_1	925409.KI911562_gene2329	4.507e-160	522.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4NH06@976|Bacteroidetes,1IUVW@117747|Sphingobacteriia	976|Bacteroidetes	HP	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_7460286_3	1237149.C900_05869	3.343e-26	111.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47K1M@768503|Cytophagia	976|Bacteroidetes	H	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_7460286_1	1168034.FH5T_02080	7.008e-208	704.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4NGKF@976|Bacteroidetes,2FP9T@200643|Bacteroidia	976|Bacteroidetes	T	regulator	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
TLS3_k127_7460286_2	641524.ADICYQ_5458	8.947e-136	438.0	COG3622@1|root,COG3622@2|Bacteria,4NG74@976|Bacteroidetes,47K7Z@768503|Cytophagia	976|Bacteroidetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
TLS3_k127_7460286_0	1123248.KB893381_gene962	8.951e-296	940.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4P2AE@976|Bacteroidetes	976|Bacteroidetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
TLS3_k127_746168_3	1121904.ARBP01000009_gene4173	3.025e-31	132.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes	976|Bacteroidetes	V	permease	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_746168_1	1121904.ARBP01000015_gene179	4.089e-89	323.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_746168_2	1121904.ARBP01000005_gene4796	1.011e-35	140.0	COG3059@1|root,COG3059@2|Bacteria,4P9H9@976|Bacteroidetes,47RAZ@768503|Cytophagia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_746168_0	1189612.A33Q_3406	5.158e-112	368.0	COG1402@1|root,COG1402@2|Bacteria,4NF2C@976|Bacteroidetes	976|Bacteroidetes	F	Creatinine amidohydrolase	crnA	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
TLS3_k127_7469195_4	1237149.C900_03621	1.7e-106	350.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,47JMY@768503|Cytophagia	976|Bacteroidetes	Q	TIGRFAM phytoene desaturase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
TLS3_k127_7469195_3	1237149.C900_03620	7.888e-119	387.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,47J9F@768503|Cytophagia	976|Bacteroidetes	I	PFAM Squalene phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
TLS3_k127_7469195_5	1237149.C900_03619	4.637e-65	227.0	COG1443@1|root,COG1443@2|Bacteria,4NFJV@976|Bacteroidetes,47Q5E@768503|Cytophagia	976|Bacteroidetes	I	NUDIX domain	idi	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
TLS3_k127_7469195_6	1122176.KB903619_gene5402	1.19e-09	60.0	2EK53@1|root,33DVI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7469195_1	468059.AUHA01000002_gene1242	1.487e-184	586.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,1IQZJ@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
TLS3_k127_7469195_0	761193.Runsl_2695	3.101e-187	608.0	COG4886@1|root,COG4886@2|Bacteria,4NG07@976|Bacteroidetes,47P4Q@768503|Cytophagia	976|Bacteroidetes	S	Chitobiase/beta-hexosaminidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Fn3_assoc,PSCyt1
TLS3_k127_7469195_2	929562.Emtol_2258	4.401e-183	574.0	COG4102@1|root,COG4102@2|Bacteria,4NE73@976|Bacteroidetes,47KYW@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TLS3_k127_7472937_0	700598.Niako_2568	0.0	1349.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IP63@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bepE_4	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
TLS3_k127_7472937_1	1506583.JQJY01000003_gene3249	1.403e-181	578.0	COG2855@1|root,COG2855@2|Bacteria,4NES6@976|Bacteroidetes,1I7Q1@117743|Flavobacteriia,2NUF2@237|Flavobacterium	976|Bacteroidetes	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
TLS3_k127_7472937_2	471854.Dfer_2053	2.297e-87	300.0	COG0226@1|root,COG0226@2|Bacteria,4NHTF@976|Bacteroidetes,47UTM@768503|Cytophagia	976|Bacteroidetes	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7472937_3	485918.Cpin_2250	1.632e-43	163.0	COG4774@1|root,COG4774@2|Bacteria,4PKB8@976|Bacteroidetes,1J0MI@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_7499577_1	1237149.C900_01307	5.215e-24	106.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47UC8@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_7499577_0	1237149.C900_02591	6.951e-270	854.0	COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_7504891_4	1121904.ARBP01000012_gene1310	3.117e-52	186.0	COG1208@1|root,COG1208@2|Bacteria,4NG3V@976|Bacteroidetes,47M37@768503|Cytophagia	976|Bacteroidetes	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	rfbF	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
TLS3_k127_7504891_1	1227739.Hsw_2795	3.706e-150	482.0	COG0451@1|root,COG0451@2|Bacteria,4NI4N@976|Bacteroidetes,47RQ3@768503|Cytophagia	976|Bacteroidetes	GM	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS3_k127_7504891_3	880070.Cycma_1332	5.762e-80	270.0	COG1898@1|root,COG1898@2|Bacteria,4NP11@976|Bacteroidetes,47PSR@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
TLS3_k127_7504891_0	1150600.ADIARSV_2156	3.965e-215	677.0	COG4091@1|root,COG4091@2|Bacteria,4NKWV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_3,Shikimate_DH
TLS3_k127_7504891_2	1121904.ARBP01000006_gene3799	2.829e-126	409.0	COG0579@1|root,COG0579@2|Bacteria,4NE0B@976|Bacteroidetes,47JS1@768503|Cytophagia	976|Bacteroidetes	S	PFAM FAD dependent oxidoreductase	lhgO	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
TLS3_k127_7517487_1	313606.M23134_05264	1.283e-177	565.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,47K1Q@768503|Cytophagia	976|Bacteroidetes	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_7517487_0	1185876.BN8_03277	8.688e-222	706.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,47K58@768503|Cytophagia	976|Bacteroidetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
TLS3_k127_7522775_1	1408224.SAMCCGM7_c3749	3.84e-57	216.0	COG2730@1|root,COG2730@2|Bacteria,1R544@1224|Proteobacteria,2U1MT@28211|Alphaproteobacteria,4BD0S@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Putative collagen-binding domain of a collagenase	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
TLS3_k127_7522775_0	1239962.C943_02207	1.564e-214	673.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,47P3I@768503|Cytophagia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF3131,Glycoamylase
TLS3_k127_7526493_1	1121481.AUAS01000005_gene2027	1.743e-57	203.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,4NFE4@976|Bacteroidetes,47Y5G@768503|Cytophagia	976|Bacteroidetes	G	Maltogenic Amylase, C-terminal domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
TLS3_k127_7526493_0	926549.KI421517_gene4008	2.067e-214	682.0	COG1640@1|root,COG3280@1|root,COG1640@2|Bacteria,COG3280@2|Bacteria,4NF7Z@976|Bacteroidetes,47NI0@768503|Cytophagia	976|Bacteroidetes	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Alpha-amylase,CBM_20,Glyco_hydro_77
TLS3_k127_7543105_1	760192.Halhy_5034	2.47e-34	135.0	2E5WH@1|root,30K07@2|Bacteria,4P5HE@976|Bacteroidetes	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
TLS3_k127_7543105_0	1237149.C900_03347	0.0	1524.0	COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,47JHP@768503|Cytophagia	976|Bacteroidetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
TLS3_k127_7544847_1	1237149.C900_02848	1.901e-26	113.0	COG1525@1|root,COG1525@2|Bacteria,4NT3S@976|Bacteroidetes,47RZB@768503|Cytophagia	976|Bacteroidetes	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
TLS3_k127_7544847_0	1189612.A33Q_2694	4.149e-85	286.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes,47NPE@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
TLS3_k127_7548905_1	1089547.KB913013_gene4057	1.249e-76	262.0	COG1309@1|root,COG1309@2|Bacteria,4NEUA@976|Bacteroidetes,47P97@768503|Cytophagia	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_7548905_3	700598.Niako_3962	1.25e-53	192.0	COG0745@1|root,COG0745@2|Bacteria,4NPID@976|Bacteroidetes	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_7548905_4	1254432.SCE1572_07840	1.408e-35	139.0	COG1720@1|root,COG1720@2|Bacteria,1MYVG@1224|Proteobacteria,42N6M@68525|delta/epsilon subdivisions,2WPY9@28221|Deltaproteobacteria,2Z0U5@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0066	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II,UPF0066
TLS3_k127_7548905_5	1279009.ADICEAN_01371	7.758e-15	76.0	2C1WN@1|root,2ZJEG@2|Bacteria,4P7BM@976|Bacteroidetes,47X20@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7548905_2	1124780.ANNU01000054_gene3508	2.641e-71	249.0	COG2761@1|root,COG2761@2|Bacteria,4NI0H@976|Bacteroidetes,47KMR@768503|Cytophagia	976|Bacteroidetes	Q	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_5
TLS3_k127_7548905_0	761193.Runsl_4471	1.203e-164	523.0	COG3546@1|root,COG3546@2|Bacteria,4NHRJ@976|Bacteroidetes,47KZB@768503|Cytophagia	976|Bacteroidetes	P	Manganese containing catalase	-	-	-	ko:K07217	-	-	-	-	ko00000	-	-	-	Mn_catalase
TLS3_k127_7550309_0	1237149.C900_05201	1.179e-92	312.0	COG1524@1|root,COG1524@2|Bacteria,4NFRQ@976|Bacteroidetes,47JI2@768503|Cytophagia	976|Bacteroidetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
TLS3_k127_7550309_2	436308.Nmar_0657	5.045e-08	60.0	COG1262@1|root,arCOG03517@2157|Archaea,41T1B@651137|Thaumarchaeota	651137|Thaumarchaeota	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
TLS3_k127_7553654_6	643867.Ftrac_2835	4.484e-75	256.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,47KPP@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
TLS3_k127_7553654_2	1237149.C900_03222	6.421e-184	585.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,47KM9@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid	kmo	-	1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
TLS3_k127_7553654_3	1237149.C900_03224	7.398e-174	558.0	COG4623@1|root,COG4623@2|Bacteria,4NHFW@976|Bacteroidetes,47NX6@768503|Cytophagia	976|Bacteroidetes	M	soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein	mltF	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
TLS3_k127_7553654_0	1279009.ADICEAN_03271	0.0	1217.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,47JMC@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
TLS3_k127_7553654_1	1237149.C900_04491	0.0	1053.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47KZ0@768503|Cytophagia	976|Bacteroidetes	E	PFAM Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
TLS3_k127_7553654_8	1279009.ADICEAN_01334	1.13e-69	245.0	COG3568@1|root,COG3568@2|Bacteria,4NHXV@976|Bacteroidetes,47NJC@768503|Cytophagia	976|Bacteroidetes	S	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_7553654_5	1237149.C900_02777	1.257e-92	312.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,47MRR@768503|Cytophagia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_7553654_4	1166018.FAES_1792	1.608e-172	545.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,47JGV@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
TLS3_k127_7553654_7	1237149.C900_02779	5.256e-70	248.0	COG1266@1|root,COG1266@2|Bacteria,4NHE1@976|Bacteroidetes,47JZ8@768503|Cytophagia	976|Bacteroidetes	S	PFAM CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
TLS3_k127_7553654_9	1237149.C900_02781	8.392e-39	148.0	COG4589@1|root,COG4589@2|Bacteria,4NIPM@976|Bacteroidetes,47KPM@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
TLS3_k127_7579536_0	1125971.ASJB01000030_gene1049	1.269e-51	203.0	COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria	201174|Actinobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
TLS3_k127_7582287_0	485918.Cpin_3691	1.286e-202	636.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1INXM@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
TLS3_k127_7582287_1	929562.Emtol_2004	2.833e-175	572.0	COG4772@1|root,COG4772@2|Bacteria,4NE9I@976|Bacteroidetes,47M2B@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
TLS3_k127_7582287_3	1237149.C900_05513	2.817e-85	291.0	COG3001@1|root,COG3001@2|Bacteria,4NEQY@976|Bacteroidetes,47K5K@768503|Cytophagia	976|Bacteroidetes	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
TLS3_k127_7582287_2	1237149.C900_00782	4.467e-149	477.0	COG0492@1|root,COG0492@2|Bacteria,4NDVS@976|Bacteroidetes,47MQ3@768503|Cytophagia	976|Bacteroidetes	O	Pyridine nucleotide-disulphide oxidoreductase	ypdA	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
TLS3_k127_758742_2	1237149.C900_03751	3.129e-77	265.0	2C52N@1|root,2Z7U1@2|Bacteria,4NEZW@976|Bacteroidetes,47PC8@768503|Cytophagia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	porT	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_758742_1	1237149.C900_03750	1.166e-110	361.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,47JXK@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
TLS3_k127_758742_0	1237149.C900_03749	6.377e-242	766.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
TLS3_k127_758742_3	1515615.HQ41_08750	1.063e-67	236.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,2FM4M@200643|Bacteroidia,22X2K@171551|Porphyromonadaceae	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
TLS3_k127_7592627_1	1121897.AUGO01000003_gene1912	1.499e-44	168.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1HYY8@117743|Flavobacteriia,2NSVP@237|Flavobacterium	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TLS3_k127_7592627_0	153721.MYP_728	4.849e-177	567.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,47KUB@768503|Cytophagia	976|Bacteroidetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
TLS3_k127_7592627_2	485918.Cpin_7008	2.654e-08	56.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
TLS3_k127_7603378_2	1267211.KI669560_gene15	0.0008195	42.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OPT
TLS3_k127_7603378_1	643867.Ftrac_0196	4.969e-172	553.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,47JX4@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM amino acid peptide transporter (Peptide H symporter), bacterial	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
TLS3_k127_7603378_0	1237149.C900_05130	2.956e-264	823.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,47JC3@768503|Cytophagia	976|Bacteroidetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
TLS3_k127_760928_0	1237149.C900_04383	4.525e-220	697.0	COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,47KBE@768503|Cytophagia	976|Bacteroidetes	M	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TPR_16,TPR_2,TPR_8
TLS3_k127_760928_1	1123277.KB893179_gene3134	2.883e-177	559.0	COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,47J9X@768503|Cytophagia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
TLS3_k127_760928_5	1434325.AZQN01000001_gene420	2.335e-17	88.0	2AT94@1|root,31IS1@2|Bacteria,4NR1S@976|Bacteroidetes,47QPI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_760928_3	929556.Solca_0342	1.23e-136	448.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,4NEV7@976|Bacteroidetes,1IPRI@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Bacterial Fmu (Sun) eukaryotic nucleolar NOL1 Nop2p	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA
TLS3_k127_760928_4	643867.Ftrac_0610	8.374e-85	295.0	COG2211@1|root,COG2211@2|Bacteria,4NTP1@976|Bacteroidetes,47UKC@768503|Cytophagia	976|Bacteroidetes	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_760928_2	1239962.C943_00184	4.671e-173	545.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,47JHX@768503|Cytophagia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
TLS3_k127_7617430_2	1519464.HY22_00855	3.746e-108	357.0	COG0025@1|root,COG0025@2|Bacteria,1FFIB@1090|Chlorobi	1090|Chlorobi	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
TLS3_k127_7617430_0	1237149.C900_00327	2.931e-131	424.0	COG0451@1|root,COG0451@2|Bacteria,4NGE6@976|Bacteroidetes,47K64@768503|Cytophagia	976|Bacteroidetes	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
TLS3_k127_7617430_1	1237149.C900_00326	7.951e-119	383.0	COG0175@1|root,COG0175@2|Bacteria,4NGVI@976|Bacteroidetes,47KPR@768503|Cytophagia	976|Bacteroidetes	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
TLS3_k127_76417_1	1123234.AUKI01000019_gene490	9.685e-166	527.0	COG1253@1|root,COG1253@2|Bacteria,4NE7C@976|Bacteroidetes,1HYD7@117743|Flavobacteriia	976|Bacteroidetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
TLS3_k127_76417_0	1237149.C900_04926	7.284e-177	570.0	COG3677@1|root,COG3677@2|Bacteria,4NFWV@976|Bacteroidetes,47MV7@768503|Cytophagia	976|Bacteroidetes	L	7TMR-DISM extracellular 2	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,Zn_Tnp_IS1595
TLS3_k127_7667144_3	700598.Niako_6657	1.018e-42	164.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,1IQ7Q@117747|Sphingobacteriia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
TLS3_k127_7667144_0	857087.Metme_0521	4.373e-177	569.0	COG0659@1|root,COG0659@2|Bacteria,1MX8F@1224|Proteobacteria,1RRCQ@1236|Gammaproteobacteria,1XDYU@135618|Methylococcales	135618|Methylococcales	P	PFAM Sulfate transporter family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfate_transp
TLS3_k127_7667144_1	985255.APHJ01000021_gene1703	5.309e-95	316.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,1HXG3@117743|Flavobacteriia,2P60E@244698|Gillisia	976|Bacteroidetes	P	Carbonic anhydrase	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
TLS3_k127_7667144_2	761193.Runsl_3452	3.303e-69	238.0	COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,47PPX@768503|Cytophagia	976|Bacteroidetes	S	PFAM Phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PRA-PH
TLS3_k127_7684010_2	1250278.JQNQ01000001_gene2097	4.039e-32	130.0	2E7PD@1|root,3324Z@2|Bacteria,4NVIR@976|Bacteroidetes,1I5UY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7684010_0	760192.Halhy_0425	7.86e-146	475.0	COG0642@1|root,COG2205@2|Bacteria,4NEIS@976|Bacteroidetes,1INVU@117747|Sphingobacteriia	976|Bacteroidetes	T	histidine kinase DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_7684010_1	491205.JARQ01000009_gene3565	2.321e-93	311.0	COG0745@1|root,COG0745@2|Bacteria,4NHXA@976|Bacteroidetes,1HZWH@117743|Flavobacteriia,3ZQ3T@59732|Chryseobacterium	976|Bacteroidetes	T	Transcriptional regulator	cusR	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_7694084_3	1237149.C900_01000	1.051e-30	126.0	COG0308@1|root,COG0308@2|Bacteria,4PNPR@976|Bacteroidetes,47YF9@768503|Cytophagia	976|Bacteroidetes	E	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_7694084_1	1237149.C900_01001	2.235e-114	381.0	COG2972@1|root,COG2972@2|Bacteria,4NIER@976|Bacteroidetes,47P26@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
TLS3_k127_7694084_0	1237149.C900_01002	2.274e-115	376.0	COG3279@1|root,COG3279@2|Bacteria,4NEAH@976|Bacteroidetes,47KUT@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_7694084_4	1519464.HY22_14065	5.227e-27	119.0	2DDRS@1|root,2ZJ0Y@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
TLS3_k127_7694084_2	643867.Ftrac_2315	6.118e-36	148.0	COG0810@1|root,COG0810@2|Bacteria,4NSYT@976|Bacteroidetes,47W0H@768503|Cytophagia	976|Bacteroidetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,TonB_C
TLS3_k127_7702710_0	1150600.ADIARSV_0832	2.852e-176	567.0	COG0642@1|root,COG3292@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1IRJZ@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_4,PAS_9,Reg_prop,Response_reg,Y_Y_Y
TLS3_k127_7707241_1	1492738.FEM21_14160	5.138e-34	146.0	COG1629@1|root,COG4219@1|root,COG1629@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,1HX6K@117743|Flavobacteriia,2NSXY@237|Flavobacterium	976|Bacteroidetes	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,Plug
TLS3_k127_7707241_0	1237149.C900_04357	1.448e-50	181.0	COG3682@1|root,COG3682@2|Bacteria,4NNVM@976|Bacteroidetes,47Q5Z@768503|Cytophagia	976|Bacteroidetes	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
TLS3_k127_7726494_2	153721.MYP_4282	1.87e-113	371.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,47K0Q@768503|Cytophagia	976|Bacteroidetes	L	TIGRFAM TIGR02757 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
TLS3_k127_7726494_1	1237149.C900_03398	2.763e-131	433.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,47NMR@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_7726494_4	1233950.IW22_03180	2.639e-69	238.0	COG0662@1|root,COG0662@2|Bacteria,4NNWT@976|Bacteroidetes,1I25A@117743|Flavobacteriia,3ZQZE@59732|Chryseobacterium	976|Bacteroidetes	G	Phosphoheptose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	MannoseP_isomer
TLS3_k127_7726494_3	421531.IX38_22655	8.648e-100	335.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,1I19J@117743|Flavobacteriia,3ZQE3@59732|Chryseobacterium	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_7726494_6	760192.Halhy_5760	4.846e-56	203.0	COG4123@1|root,COG4123@2|Bacteria,4NG1X@976|Bacteroidetes,1ISSS@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	smtA	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
TLS3_k127_7726494_5	1237149.C900_05616	1.834e-66	232.0	COG2353@1|root,COG2353@2|Bacteria,4NPGK@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_7726494_7	1237149.C900_05615	1.61e-43	164.0	COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,47QE6@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulator	slyA	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
TLS3_k127_7726494_0	1237149.C900_05611	2.415e-217	679.0	COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes,47JSX@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
TLS3_k127_7729720_3	1233950.IW22_13855	4.734e-69	239.0	COG2411@1|root,COG2411@2|Bacteria,4PGE4@976|Bacteroidetes,1IH98@117743|Flavobacteriia,3ZTIU@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7729720_4	1506583.JQJY01000009_gene858	3.62e-53	204.0	28J4T@1|root,2Z90P@2|Bacteria,4NHUC@976|Bacteroidetes,1HZE4@117743|Flavobacteriia,2NUFS@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
TLS3_k127_7729720_0	1121890.AUDO01000008_gene2705	2.094e-96	326.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1HY2Q@117743|Flavobacteriia,2NTYA@237|Flavobacterium	976|Bacteroidetes	S	Galactose oxidase, central domain	nanM	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6
TLS3_k127_7729720_2	925409.KI911562_gene968	2.073e-78	274.0	COG2972@1|root,COG2972@2|Bacteria,4NHM5@976|Bacteroidetes,1IRRM@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
TLS3_k127_7729720_1	929556.Solca_2910	9.541e-90	301.0	COG3279@1|root,COG3279@2|Bacteria,4NI3K@976|Bacteroidetes,1J04E@117747|Sphingobacteriia	976|Bacteroidetes	K	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_7732507_1	1123278.KB893559_gene2969	4.223e-143	460.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,47JUZ@768503|Cytophagia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	-	-	1.1.1.410	ko:K22025	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
TLS3_k127_7732507_0	1123277.KB893184_gene4103	1.907e-178	570.0	COG3395@1|root,COG3395@2|Bacteria,4NJY2@976|Bacteroidetes,47NM5@768503|Cytophagia	976|Bacteroidetes	S	Putative nucleotide-binding of sugar-metabolising enzyme	-	-	2.7.1.219,2.7.1.220	ko:K22129	-	-	-	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
TLS3_k127_7732507_2	522306.CAP2UW1_3196	1.953e-136	439.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,2VHGI@28216|Betaproteobacteria	28216|Betaproteobacteria	G	fructose-bisphosphate aldolase, class II, Calvin cycle subtype	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
TLS3_k127_774390_0	1237149.C900_03740	4.558e-79	277.0	28J2U@1|root,2Z8Z5@2|Bacteria,4NHYM@976|Bacteroidetes,47RCK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_774390_3	1239962.C943_00810	8.478e-46	171.0	COG0394@1|root,COG0394@2|Bacteria,4NNQZ@976|Bacteroidetes,47R52@768503|Cytophagia	976|Bacteroidetes	T	Low molecular weight phosphotyrosine protein phosphatase	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
TLS3_k127_774390_1	1042376.AFPK01000014_gene400	9.469e-62	219.0	COG1670@1|root,COG1670@2|Bacteria,4NMRH@976|Bacteroidetes,1I1FG@117743|Flavobacteriia,4070K@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	J	Domain of unknown function (DUF4202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4202
TLS3_k127_774390_2	925409.KI911562_gene1783	3.848e-60	216.0	COG4758@1|root,COG4758@2|Bacteria,4NQRE@976|Bacteroidetes,1ISAD@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane protein (DUF2154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
TLS3_k127_774390_4	485918.Cpin_6588	4.801e-13	72.0	2EC7G@1|root,33661@2|Bacteria,4NWXP@976|Bacteroidetes,1IU01@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4288)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4288
TLS3_k127_7744211_4	1121957.ATVL01000010_gene208	1.255e-32	130.0	COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,47QWF@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
TLS3_k127_7744211_0	1237149.C900_04727	8.778e-140	452.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,47JTZ@768503|Cytophagia	976|Bacteroidetes	S	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
TLS3_k127_7744211_2	1237149.C900_04726	6.456e-85	284.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,47PDT@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
TLS3_k127_7744211_1	398720.MED217_04472	1.086e-103	346.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,1HXJ4@117743|Flavobacteriia,2XII1@283735|Leeuwenhoekiella	976|Bacteroidetes	H	Pterin binding enzyme	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
TLS3_k127_7744211_3	1237149.C900_04724	1.309e-54	196.0	COG1624@1|root,COG1624@2|Bacteria,4NG3Z@976|Bacteroidetes,47JT6@768503|Cytophagia	976|Bacteroidetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
TLS3_k127_7744424_1	378806.STAUR_3895	4.537e-17	81.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria,1R85W@1224|Proteobacteria	1224|Proteobacteria	M	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494,VPEP
TLS3_k127_7744424_0	643867.Ftrac_0100	2.58e-129	424.0	COG3420@1|root,COG5184@1|root,COG3420@2|Bacteria,COG5184@2|Bacteria,4NMRB@976|Bacteroidetes,47QVY@768503|Cytophagia	976|Bacteroidetes	P	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494
TLS3_k127_7744424_2	1305737.JAFX01000001_gene1969	1.871e-07	62.0	COG2220@1|root,COG2220@2|Bacteria,4NFJ4@976|Bacteroidetes,47JCF@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
TLS3_k127_7750675_3	1237149.C900_05519	3.614e-75	258.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,47NAQ@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_7750675_5	1237149.C900_05518	7.638e-58	210.0	COG4585@1|root,COG4585@2|Bacteria,4NN4R@976|Bacteroidetes,47N81@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TLS3_k127_7750675_7	313606.M23134_07736	3.824e-23	108.0	2ECA3@1|root,32QV4@2|Bacteria,4NRYD@976|Bacteroidetes,47QR1@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7750675_8	313606.M23134_07736	1.916e-17	91.0	2ECA3@1|root,32QV4@2|Bacteria,4NRYD@976|Bacteroidetes,47QR1@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7750675_0	1237149.C900_05514	8.749e-152	489.0	COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,47KC8@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	-	-	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
TLS3_k127_7750675_6	1237149.C900_00783	2.658e-43	163.0	COG0454@1|root,COG0456@2|Bacteria,4NT3M@976|Bacteroidetes,47VFK@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_7750675_4	1237149.C900_00788	1.366e-65	229.0	COG0251@1|root,COG0251@2|Bacteria,4NPF9@976|Bacteroidetes,47QAB@768503|Cytophagia	976|Bacteroidetes	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
TLS3_k127_7750675_2	1237149.C900_00789	1.176e-92	308.0	COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,47PXB@768503|Cytophagia	976|Bacteroidetes	L	PFAM methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
TLS3_k127_7750675_1	1237149.C900_00792	4.955e-120	392.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,47M9W@768503|Cytophagia	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TLS3_k127_7752678_1	1189612.A33Q_0936	6.052e-174	551.0	COG0205@1|root,COG0205@2|Bacteria,4NGN7@976|Bacteroidetes,47TRF@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
TLS3_k127_7752678_0	1279009.ADICEAN_00229	1.07e-182	578.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,47K8V@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
TLS3_k127_7752678_8	1237149.C900_00642	6.71e-57	201.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,47Q95@768503|Cytophagia	976|Bacteroidetes	FG	HIT family hydrolase	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
TLS3_k127_7752678_7	1237149.C900_00641	3.581e-67	232.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,47P7N@768503|Cytophagia	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
TLS3_k127_7752678_4	1237149.C900_00640	1.122e-140	451.0	COG1357@1|root,COG1357@2|Bacteria,4NY1Q@976|Bacteroidetes,47WKP@768503|Cytophagia	976|Bacteroidetes	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
TLS3_k127_7752678_5	1189612.A33Q_3481	9.411e-112	369.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,47K6J@768503|Cytophagia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TLS3_k127_7752678_2	643867.Ftrac_3194	9.513e-159	513.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,47JTX@768503|Cytophagia	976|Bacteroidetes	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
TLS3_k127_7752678_6	926549.KI421517_gene1544	8.298e-100	332.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,47KWT@768503|Cytophagia	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
TLS3_k127_7752678_3	1237149.C900_00636	8.194e-142	456.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,47MC9@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
TLS3_k127_7763595_0	1237149.C900_01494	2.94e-174	557.0	COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_7763595_2	421531.IX38_12415	5.158e-18	88.0	2CBBA@1|root,3313Q@2|Bacteria,4NWRR@976|Bacteroidetes,1IJEV@117743|Flavobacteriia,3ZSPC@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7763595_1	509635.N824_26345	3.368e-50	184.0	COG1595@1|root,COG1595@2|Bacteria,4NQR9@976|Bacteroidetes,1IST5@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_7772363_2	1492738.FEM21_28260	1.071e-16	81.0	COG1850@1|root,COG1850@2|Bacteria,4NFRC@976|Bacteroidetes,1ICX3@117743|Flavobacteriia,2NVT5@237|Flavobacterium	976|Bacteroidetes	G	Pfam Ribulose bisphosphate carboxylase large chain, catalytic domain	-	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
TLS3_k127_7772363_0	1185876.BN8_06003	3.049e-157	501.0	COG1879@1|root,COG1879@2|Bacteria,4NKXR@976|Bacteroidetes,47U11@768503|Cytophagia	976|Bacteroidetes	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
TLS3_k127_7772363_1	1185876.BN8_06002	1.017e-127	416.0	COG1172@1|root,COG1172@2|Bacteria,4NHD9@976|Bacteroidetes,47KFH@768503|Cytophagia	976|Bacteroidetes	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10439,ko:K10440	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
TLS3_k127_7786084_0	761193.Runsl_2443	0.0	1197.0	COG2133@1|root,COG3291@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4654@2|Bacteria,4NKBN@976|Bacteroidetes,47JFX@768503|Cytophagia	976|Bacteroidetes	C	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	CBM_6,Cytochrom_C,GSDH,PKD
TLS3_k127_7786084_1	925409.KI911562_gene1595	1.417e-118	389.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes	976|Bacteroidetes	G	Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_7786084_2	1121904.ARBP01000011_gene1562	3.731e-44	161.0	COG2220@1|root,COG2220@2|Bacteria,4NFJ4@976|Bacteroidetes,47JCF@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
TLS3_k127_7795023_3	485918.Cpin_1923	9.335e-60	210.0	COG0059@1|root,COG0059@2|Bacteria,4NFYV@976|Bacteroidetes,1IQ69@117747|Sphingobacteriia	976|Bacteroidetes	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
TLS3_k127_7795023_1	485918.Cpin_1921	3.708e-244	766.0	COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,1IPTP@117747|Sphingobacteriia	976|Bacteroidetes	EH	Acetolactate synthase, large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TLS3_k127_7795023_0	1122605.KB893630_gene4045	7.35e-282	874.0	COG0129@1|root,COG0129@2|Bacteria,4NFHP@976|Bacteroidetes,1IPT9@117747|Sphingobacteriia	976|Bacteroidetes	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
TLS3_k127_7795023_2	468059.AUHA01000004_gene2076	3.376e-121	395.0	COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes,1IPAA@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_7800137_1	1123276.KB893247_gene136	2.212e-214	679.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,COG4654@2|Bacteria,4NDVK@976|Bacteroidetes,47MAT@768503|Cytophagia	976|Bacteroidetes	CG	Cytochrome c, class I	-	-	-	ko:K08738,ko:K09992	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	CBM_6,Cytochrom_C,Cytochrome_CBB3,GSDH,PKD,ThuA
TLS3_k127_7800137_0	1144313.PMI10_02937	4.479e-234	740.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1HXAT@117743|Flavobacteriia,2NV5I@237|Flavobacterium	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
TLS3_k127_7800137_3	1250232.JQNJ01000001_gene269	2.04e-39	149.0	COG0662@1|root,COG0662@2|Bacteria,4NTZN@976|Bacteroidetes	976|Bacteroidetes	G	ARD/ARD' family	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_7800137_2	655815.ZPR_2730	8.656e-169	534.0	COG3507@1|root,COG3507@2|Bacteria,4NEIZ@976|Bacteroidetes,1HZ1J@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
TLS3_k127_7805945_0	666685.R2APBS1_0794	1.976e-223	715.0	COG0823@1|root,COG0823@2|Bacteria,1R1F4@1224|Proteobacteria,1T0CM@1236|Gammaproteobacteria,1X5C1@135614|Xanthomonadales	135614|Xanthomonadales	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_7805945_1	1178537.BA1_03485	9.836e-10	59.0	COG0454@1|root,COG0456@2|Bacteria,1V4AF@1239|Firmicutes,4HD36@91061|Bacilli,1ZCVH@1386|Bacillus	91061|Bacilli	K	Acetyltransferase (GNAT) family	yodP	-	2.3.1.264	ko:K21935	-	-	R11701	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_9
TLS3_k127_7830904_2	1237149.C900_01027	9.509e-61	216.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,47KWQ@768503|Cytophagia	976|Bacteroidetes	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
TLS3_k127_7830904_4	1124780.ANNU01000005_gene2405	1.141e-47	176.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,47R21@768503|Cytophagia	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7830904_0	1237149.C900_01029	1.975e-275	857.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,47JSM@768503|Cytophagia	976|Bacteroidetes	M	Penicillin-binding protein, dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
TLS3_k127_7830904_1	1237149.C900_01030	2.518e-172	550.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,47JVQ@768503|Cytophagia	976|Bacteroidetes	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
TLS3_k127_7830904_3	1237149.C900_01031	6.455e-60	220.0	COG3827@1|root,COG3827@2|Bacteria,4PMMQ@976|Bacteroidetes,47Y53@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7843473_3	1296416.JACB01000027_gene4078	9.485e-54	190.0	COG0823@1|root,COG0823@2|Bacteria,4NIV7@976|Bacteroidetes,1HYWC@117743|Flavobacteriia,2YI86@290174|Aquimarina	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_7843473_0	1237149.C900_00871	4.227e-120	395.0	COG2220@1|root,COG2220@2|Bacteria,4NENZ@976|Bacteroidetes,47MND@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
TLS3_k127_7843473_2	926549.KI421517_gene521	2.07e-55	198.0	COG0346@1|root,COG0346@2|Bacteria,4NSC9@976|Bacteroidetes,47RDB@768503|Cytophagia	976|Bacteroidetes	E	Glyoxalase-like domain	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
TLS3_k127_7843473_1	700598.Niako_5055	4.782e-109	364.0	COG0657@1|root,COG0657@2|Bacteria,4NH62@976|Bacteroidetes,1IQ0H@117747|Sphingobacteriia	976|Bacteroidetes	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
TLS3_k127_7849779_1	153721.MYP_3158	1.324e-58	219.0	28HFP@1|root,2Z7RP@2|Bacteria,4NHVI@976|Bacteroidetes,47NP6@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857
TLS3_k127_7849779_0	880071.Fleli_1325	1.427e-139	466.0	COG1305@1|root,COG1305@2|Bacteria,4NI6P@976|Bacteroidetes,47KR7@768503|Cytophagia	976|Bacteroidetes	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
TLS3_k127_7849779_2	1121957.ATVL01000006_gene2930	2.233e-16	85.0	COG0457@1|root,COG2849@1|root,COG0457@2|Bacteria,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47N8G@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TPR_1,TPR_16,TPR_8
TLS3_k127_7856063_0	667015.Bacsa_1059	3.415e-149	480.0	COG0332@1|root,COG0332@2|Bacteria,4NE5Q@976|Bacteroidetes,2FQSW@200643|Bacteroidia,4AQ61@815|Bacteroidaceae	976|Bacteroidetes	H	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	darB	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III_C,Thiolase_N,ketoacyl-synt
TLS3_k127_7856063_1	483216.BACEGG_00427	8.637e-16	82.0	COG1309@1|root,COG1309@2|Bacteria,4NWKT@976|Bacteroidetes,2FTJV@200643|Bacteroidia,4AVIX@815|Bacteroidaceae	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_7857817_2	1237149.C900_01796	1.399e-177	563.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,47JES@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the arginase family	-	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS3_k127_7857817_1	643867.Ftrac_0441	2.981e-181	583.0	COG3447@1|root,COG4251@1|root,COG3447@2|Bacteria,COG4251@2|Bacteria,4NI5R@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1
TLS3_k127_7857817_3	1185876.BN8_00115	9.244e-94	319.0	COG4313@1|root,COG4313@2|Bacteria,4PPSZ@976|Bacteroidetes,47YRZ@768503|Cytophagia	976|Bacteroidetes	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7857817_0	1120965.AUBV01000003_gene308	1.486e-249	773.0	COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,47NPF@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
TLS3_k127_7857817_4	714943.Mucpa_5527	3.713e-48	179.0	COG0460@1|root,COG0460@2|Bacteria,4NHRC@976|Bacteroidetes,1IPM4@117747|Sphingobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
TLS3_k127_7858677_8	1123248.KB893381_gene999	1.179e-57	201.0	COG1082@1|root,COG1082@2|Bacteria,4NK9X@976|Bacteroidetes	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
TLS3_k127_7858677_2	1123248.KB893381_gene1000	6.635e-132	424.0	COG1028@1|root,COG1028@2|Bacteria,4NK3I@976|Bacteroidetes	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_7858677_0	1123277.KB893211_gene4416	2.348e-209	652.0	COG1063@1|root,COG1063@2|Bacteria,4NFSK@976|Bacteroidetes,47XCK@768503|Cytophagia	976|Bacteroidetes	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_7858677_1	1288963.ADIS_1148	5.229e-133	426.0	COG0269@1|root,COG0269@2|Bacteria,4NHBV@976|Bacteroidetes	976|Bacteroidetes	G	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.2.43	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05338	RC00421,RC00422	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
TLS3_k127_7858677_9	313606.M23134_03263	7.681e-51	185.0	COG1595@1|root,COG1595@2|Bacteria,4NETF@976|Bacteroidetes,47QDK@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_7858677_4	1237149.C900_00263	1.497e-99	340.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47JD6@768503|Cytophagia	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	fpp2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
TLS3_k127_7858677_11	1237149.C900_00351	2.656e-16	92.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,CHU_C,Exo_endo_phos,Glyco_hydro_43,Laminin_G_3,PKD,Peptidase_M43,fn3
TLS3_k127_7858677_7	1237149.C900_00350	1.842e-76	273.0	COG2885@1|root,COG2885@2|Bacteria,4PIU2@976|Bacteroidetes,47SAQ@768503|Cytophagia	976|Bacteroidetes	M	Pfam:DUF3308	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_7858677_10	1121904.ARBP01000003_gene6137	1.088e-23	104.0	2CFU8@1|root,2ZXDP@2|Bacteria,4P8HP@976|Bacteroidetes,47WQV@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7858677_6	1121904.ARBP01000003_gene6138	4.275e-79	271.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,47MTX@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_7858677_5	1121904.ARBP01000003_gene6139	8.405e-95	321.0	COG3275@1|root,COG3275@2|Bacteria,4PN8S@976|Bacteroidetes,47PB8@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_7858677_3	504487.JCM19302_927	4.715e-115	386.0	COG2335@1|root,COG2335@2|Bacteria,4NH49@976|Bacteroidetes,1HXZS@117743|Flavobacteriia	976|Bacteroidetes	M	Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
TLS3_k127_7868408_2	755732.Fluta_3487	1.256e-15	78.0	COG2102@1|root,COG2102@2|Bacteria,4NFQ4@976|Bacteroidetes,1HYJK@117743|Flavobacteriia	976|Bacteroidetes	S	atp-binding	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
TLS3_k127_7868408_1	1124780.ANNU01000008_gene2722	4.723e-114	377.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,47M9T@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM LAO AO transport system ATPase	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
TLS3_k127_7868408_0	1237149.C900_03797	1.287e-120	400.0	COG4252@1|root,COG4252@2|Bacteria,4NMM6@976|Bacteroidetes,47PFU@768503|Cytophagia	976|Bacteroidetes	T	CHASE2 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2
TLS3_k127_7900655_1	1237149.C900_03691	5e-119	397.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,47JHI@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TLS3_k127_7900655_2	316067.Geob_0474	1.079e-115	391.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
TLS3_k127_7900655_0	929703.KE386491_gene3242	5.563e-140	467.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,47M8Q@768503|Cytophagia	976|Bacteroidetes	CP	NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
TLS3_k127_7900655_5	153721.MYP_280	1.733e-25	108.0	COG0713@1|root,COG0713@2|Bacteria,4NSR8@976|Bacteroidetes,47R5R@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
TLS3_k127_7900655_4	1237149.C900_03687	1.042e-34	139.0	COG0839@1|root,COG0839@2|Bacteria,4NNMC@976|Bacteroidetes,47PS1@768503|Cytophagia	976|Bacteroidetes	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
TLS3_k127_7900655_3	1237149.C900_03686	7.101e-79	269.0	COG1143@1|root,COG1143@2|Bacteria,4NGWR@976|Bacteroidetes,47MDD@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	ndhI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
TLS3_k127_7907391_0	679937.Bcop_2316	3.488e-251	781.0	COG3039@1|root,COG3039@2|Bacteria,4NF00@976|Bacteroidetes,2FVB1@200643|Bacteroidia,4ASJ5@815|Bacteroidaceae	976|Bacteroidetes	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
TLS3_k127_7918203_3	1237149.C900_00538	5.01e-52	188.0	COG1975@1|root,COG1975@2|Bacteria,4NG02@976|Bacteroidetes,47JA8@768503|Cytophagia	976|Bacteroidetes	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
TLS3_k127_7918203_0	1237149.C900_00537	3.328e-282	887.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47KVI@768503|Cytophagia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
TLS3_k127_7918203_2	1237149.C900_00536	5.303e-75	254.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,47XN3@768503|Cytophagia	976|Bacteroidetes	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
TLS3_k127_7918203_4	1237149.C900_00534	2.035e-36	143.0	COG2010@1|root,COG2010@2|Bacteria,4NEXP@976|Bacteroidetes,47R7P@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrom_C,Cytochrome_CBB3
TLS3_k127_7918203_1	925409.KI911562_gene991	1.272e-276	863.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1IR1H@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Aldehyde oxidase xanthine dehydrogenase, molybdopterin binding	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
TLS3_k127_7921901_2	1237149.C900_04079	4.53e-127	420.0	COG1538@1|root,COG1538@2|Bacteria,4NU3A@976|Bacteroidetes,47P0C@768503|Cytophagia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_7921901_3	1237149.C900_04080	1.85e-124	402.0	COG1136@1|root,COG1136@2|Bacteria,4NEC5@976|Bacteroidetes,47N33@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
TLS3_k127_7921901_6	760192.Halhy_3187	1.649e-28	121.0	COG2885@1|root,COG2885@2|Bacteria,4P5MU@976|Bacteroidetes	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
TLS3_k127_7921901_0	1122179.KB890434_gene825	4.884e-226	711.0	COG1793@1|root,COG1793@2|Bacteria,4NEKP@976|Bacteroidetes,1IQCK@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase	lig	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
TLS3_k127_7921901_1	1237149.C900_05703	1.065e-151	486.0	COG1236@1|root,COG1236@2|Bacteria,4NFN7@976|Bacteroidetes,47JDM@768503|Cytophagia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Lactamase_B
TLS3_k127_7921901_5	1237149.C900_04850	8.455e-33	133.0	COG2062@1|root,COG2062@2|Bacteria,4PMDV@976|Bacteroidetes,47Y2D@768503|Cytophagia	976|Bacteroidetes	T	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
TLS3_k127_7921901_4	1237149.C900_04851	3.564e-44	166.0	2CM2H@1|root,32SDI@2|Bacteria,4NSAF@976|Bacteroidetes,47R71@768503|Cytophagia	976|Bacteroidetes	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
TLS3_k127_7939828_4	1499967.BAYZ01000167_gene6760	1.426e-49	182.0	COG2204@1|root,COG3829@1|root,COG2204@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	ko:K15836	-	-	-	-	ko00000,ko03000	-	-	-	GAF_2,HTH_8,PAS_9,Response_reg,Sigma54_activat
TLS3_k127_7939828_1	1239962.C943_00988	1.455e-225	705.0	COG2704@1|root,COG2704@2|Bacteria,4NGDF@976|Bacteroidetes,47T5H@768503|Cytophagia	976|Bacteroidetes	S	Anaerobic c4-dicarboxylate membrane transporter	-	-	-	ko:K07791,ko:K07792	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.13.1	-	-	DcuA_DcuB
TLS3_k127_7939828_3	1239962.C943_00987	2.11e-200	627.0	COG0252@1|root,COG0252@2|Bacteria,4NFKG@976|Bacteroidetes,47MY9@768503|Cytophagia	976|Bacteroidetes	EJ	Asparaginase	ansB	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
TLS3_k127_7939828_0	1341181.FLJC2902T_15860	5.597e-263	815.0	COG1027@1|root,COG1027@2|Bacteria,4P1PR@976|Bacteroidetes,1HZDD@117743|Flavobacteriia,2NU65@237|Flavobacterium	976|Bacteroidetes	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
TLS3_k127_7939828_2	1239962.C943_00985	3.751e-201	631.0	COG3637@1|root,COG3637@2|Bacteria,4NGSV@976|Bacteroidetes	976|Bacteroidetes	M	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
TLS3_k127_7953601_1	1237149.C900_03317	2.145e-79	272.0	28KF8@1|root,2ZA1G@2|Bacteria,4NK7X@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7953601_4	5911.EAR82403	9.472e-11	73.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
TLS3_k127_7953601_3	1454202.PPBDW_130020___1	1.438e-14	79.0	COG3187@1|root,COG3187@2|Bacteria,1RFSD@1224|Proteobacteria,1S6MZ@1236|Gammaproteobacteria,1XWWJ@135623|Vibrionales	135623|Vibrionales	O	heat shock protein	-	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	META
TLS3_k127_7953601_2	1120925.F941_00035	8.395e-27	112.0	COG2388@1|root,COG2388@2|Bacteria,1N6YS@1224|Proteobacteria,1SG8R@1236|Gammaproteobacteria,3NSWD@468|Moraxellaceae	1236|Gammaproteobacteria	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
TLS3_k127_7953601_0	504472.Slin_6004	3.713e-81	281.0	COG3547@1|root,COG3547@2|Bacteria,4NKDC@976|Bacteroidetes,47NU4@768503|Cytophagia	976|Bacteroidetes	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
TLS3_k127_7970712_2	926549.KI421517_gene4122	1.501e-175	557.0	COG3507@1|root,COG3507@2|Bacteria,4NEWE@976|Bacteroidetes,47MJY@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	xynB	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
TLS3_k127_7970712_5	313606.M23134_07146	2.691e-28	119.0	COG0328@1|root,COG0328@2|Bacteria,4NZ41@976|Bacteroidetes,47T0B@768503|Cytophagia	976|Bacteroidetes	L	RNase H	-	-	-	-	-	-	-	-	-	-	-	-	RNase_H
TLS3_k127_7970712_6	1487921.DP68_06660	3.577e-20	101.0	2ET8I@1|root,3147J@2|Bacteria,1USUA@1239|Firmicutes,24ZT1@186801|Clostridia,36QDI@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7970712_4	700598.Niako_0627	7.731e-38	147.0	COG0500@1|root,COG0500@2|Bacteria,4PN8K@976|Bacteroidetes	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_7970712_0	1237149.C900_03059	5.288e-221	710.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_7970712_7	1121930.AQXG01000017_gene3165	3.01e-17	90.0	2FECF@1|root,346C7@2|Bacteria,4P54D@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7970712_1	1123276.KB893252_gene3717	2.414e-176	564.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,47K24@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
TLS3_k127_7970712_3	504472.Slin_5365	1.022e-46	171.0	COG1131@1|root,COG1131@2|Bacteria,4NJ0D@976|Bacteroidetes,47K40@768503|Cytophagia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_7983604_1	234267.Acid_5969	6.086e-88	307.0	COG0076@1|root,COG0076@2|Bacteria,3Y365@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
TLS3_k127_7983604_0	41431.PCC8801_0005	1.255e-90	304.0	COG2020@1|root,COG2020@2|Bacteria,1G4HN@1117|Cyanobacteria,3KGIV@43988|Cyanothece	1117|Cyanobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
TLS3_k127_7984173_0	760192.Halhy_0750	0.0	1173.0	COG3250@1|root,COG3250@2|Bacteria,4NFPC@976|Bacteroidetes,1IQJ2@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	cbgA_1	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
TLS3_k127_7984173_3	929556.Solca_1281	7.165e-88	297.0	28I6D@1|root,2Z89E@2|Bacteria,4NIIX@976|Bacteroidetes,1IR84@117747|Sphingobacteriia	976|Bacteroidetes	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
TLS3_k127_7984173_4	313606.M23134_02512	1.217e-21	105.0	2FG5W@1|root,3482C@2|Bacteria,4P5PR@976|Bacteroidetes,47VV9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7984173_2	471854.Dfer_1199	1.069e-99	333.0	COG2897@1|root,COG2897@2|Bacteria,4NF85@976|Bacteroidetes,47PN4@768503|Cytophagia	976|Bacteroidetes	P	Rhodanese Homology Domain	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
TLS3_k127_7984173_1	700598.Niako_0765	4.238e-185	585.0	COG2252@1|root,COG2252@2|Bacteria,4NGCG@976|Bacteroidetes,1IRJ0@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Permease family	yieG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
TLS3_k127_7986762_0	643867.Ftrac_1494	2.338e-135	440.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,47MIV@768503|Cytophagia	976|Bacteroidetes	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS3_k127_7986762_2	1469607.KK073768_gene307	3.111e-36	143.0	COG3385@1|root,COG3385@2|Bacteria,1G2W3@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
TLS3_k127_7986762_1	485913.Krac_9440	2.475e-66	231.0	COG1961@1|root,COG1961@2|Bacteria,2G981@200795|Chloroflexi	200795|Chloroflexi	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
TLS3_k127_7990180_1	388413.ALPR1_13595	4.677e-80	269.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,47MHE@768503|Cytophagia	976|Bacteroidetes	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
TLS3_k127_7990180_3	1237149.C900_00629	8.682e-53	192.0	COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,47PSK@768503|Cytophagia	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
TLS3_k127_7990180_2	153721.MYP_3528	3.454e-72	249.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,47MZS@768503|Cytophagia	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
TLS3_k127_7990180_0	1124780.ANNU01000044_gene492	7.239e-169	535.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,47KV4@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
TLS3_k127_7992867_3	926549.KI421517_gene1458	2.231e-31	125.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,47PEN@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
TLS3_k127_7992867_1	1338011.BD94_3358	2.869e-45	169.0	COG1595@1|root,COG1595@2|Bacteria,4NETF@976|Bacteroidetes,1HXWP@117743|Flavobacteriia,34QDV@308865|Elizabethkingia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	sigG	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_7992867_4	929703.KE386491_gene3664	2.872e-10	68.0	2EJIX@1|root,33D9U@2|Bacteria,4NXKW@976|Bacteroidetes,47SWM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7992867_2	1185876.BN8_05850	5.656e-40	160.0	COG3735@1|root,COG3735@2|Bacteria,4NN4U@976|Bacteroidetes,47QPY@768503|Cytophagia	976|Bacteroidetes	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
TLS3_k127_7992867_0	314230.DSM3645_07465	2.596e-60	215.0	COG3931@1|root,COG3931@2|Bacteria,2J373@203682|Planctomycetes	203682|Planctomycetes	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
TLS3_k127_7998187_0	1166018.FAES_1088	1.708e-231	719.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,47JYT@768503|Cytophagia	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
TLS3_k127_7998187_6	1237149.C900_04669	3.76e-21	96.0	COG0690@1|root,COG0690@2|Bacteria,4NX53@976|Bacteroidetes,47RVC@768503|Cytophagia	976|Bacteroidetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
TLS3_k127_7998187_2	1237149.C900_04670	5.596e-104	339.0	COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,47KBF@768503|Cytophagia	976|Bacteroidetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
TLS3_k127_7998187_3	1120968.AUBX01000016_gene1757	9.302e-77	258.0	COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,47PEZ@768503|Cytophagia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
TLS3_k127_7998187_1	1237149.C900_04672	1.234e-112	367.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,47JJZ@768503|Cytophagia	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
TLS3_k127_7998187_4	1237149.C900_04673	1.677e-68	236.0	COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,47JGP@768503|Cytophagia	976|Bacteroidetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
TLS3_k127_7998187_5	643867.Ftrac_3024	4.945e-50	180.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,47PSQ@768503|Cytophagia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
TLS3_k127_7998187_7	1124780.ANNU01000035_gene249	2.913e-10	61.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,47JXH@768503|Cytophagia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
TLS3_k127_8001324_0	1237149.C900_02605	1.005e-172	572.0	COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,47MS3@768503|Cytophagia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
TLS3_k127_8002542_5	1048983.EL17_20700	5.91e-29	124.0	COG4251@1|root,COG4251@2|Bacteria,4NXD8@976|Bacteroidetes	976|Bacteroidetes	T	negative regulation of phosphorylation	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4
TLS3_k127_8002542_0	1408473.JHXO01000011_gene3168	2.048e-209	663.0	COG1680@1|root,COG1729@1|root,COG1680@2|Bacteria,COG1729@2|Bacteria,4NI1Z@976|Bacteroidetes,2FUDK@200643|Bacteroidia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
TLS3_k127_8002542_4	1121904.ARBP01000001_gene5725	1.303e-51	193.0	COG3206@1|root,COG3206@2|Bacteria,4NP00@976|Bacteroidetes,47R2R@768503|Cytophagia	976|Bacteroidetes	M	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
TLS3_k127_8002542_1	929562.Emtol_2157	1.502e-126	408.0	COG3828@1|root,COG3828@2|Bacteria,4NJ6A@976|Bacteroidetes,47PB3@768503|Cytophagia	976|Bacteroidetes	G	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
TLS3_k127_8002542_2	700598.Niako_0425	5.759e-88	295.0	COG4122@1|root,COG4122@2|Bacteria,4NMF5@976|Bacteroidetes,1IWQE@117747|Sphingobacteriia	976|Bacteroidetes	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
TLS3_k127_8002542_3	926549.KI421517_gene2442	2.024e-62	216.0	COG0673@1|root,COG0673@2|Bacteria,4NE75@976|Bacteroidetes,47JGE@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_8004488_0	643867.Ftrac_1730	9.943e-211	682.0	COG3292@1|root,COG4251@1|root,COG3292@2|Bacteria,COG4251@2|Bacteria,4NKGA@976|Bacteroidetes	976|Bacteroidetes	KT	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,SpoIIE,Y_Y_Y
TLS3_k127_8004488_3	1248760.ANFZ01000008_gene1586	1.183e-05	49.0	2AMIC@1|root,31CE1@2|Bacteria,1Q8GT@1224|Proteobacteria,2VEPT@28211|Alphaproteobacteria,2K889@204457|Sphingomonadales	204457|Sphingomonadales	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
TLS3_k127_8004488_2	1237149.C900_02612	3.782e-113	373.0	COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,47NTZ@768503|Cytophagia	976|Bacteroidetes	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
TLS3_k127_8004488_1	1237149.C900_02611	1.661e-127	411.0	COG1028@1|root,COG1028@2|Bacteria,4NE45@976|Bacteroidetes,47JX5@768503|Cytophagia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase SDR	ykuF	-	-	ko:K13774	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short_C2
TLS3_k127_8012268_2	1279009.ADICEAN_00177	4.104e-62	216.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,47ME4@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
TLS3_k127_8012268_1	1237149.C900_04650	4.064e-191	604.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,47JQD@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the thiolase family	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
TLS3_k127_8012268_0	1237149.C900_04649	7.568e-312	962.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,47KH2@768503|Cytophagia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_8014010_2	765913.ThidrDRAFT_2980	1.292e-71	246.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,1WXFY@135613|Chromatiales	135613|Chromatiales	G	Glycosyltransferase 36 associated	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
TLS3_k127_8014010_1	866536.Belba_2454	6.771e-78	261.0	COG0652@1|root,COG0652@2|Bacteria,4NKQ7@976|Bacteroidetes,47P72@768503|Cytophagia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
TLS3_k127_8014010_3	929556.Solca_2685	6.517e-13	78.0	COG3637@1|root,COG3637@2|Bacteria,4NV08@976|Bacteroidetes,1ITUR@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_8014010_0	1237149.C900_02172	1.242e-98	340.0	COG0642@1|root,COG2205@2|Bacteria,4NG0Y@976|Bacteroidetes,47JUV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
TLS3_k127_8014864_3	172045.KS04_14195	1.88e-61	224.0	COG0642@1|root,COG0642@2|Bacteria,4NEW4@976|Bacteroidetes,1HZ62@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_8014864_2	172045.KS04_14190	7.957e-95	315.0	COG0745@1|root,COG0745@2|Bacteria,4NGVV@976|Bacteroidetes,1HXES@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_8014864_5	714943.Mucpa_1451	7.888e-22	96.0	2E4IE@1|root,32ZDH@2|Bacteria,4NUR6@976|Bacteroidetes,1IU61@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
TLS3_k127_8014864_1	1123248.KB893370_gene4976	3.922e-139	448.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1IQG3@117747|Sphingobacteriia	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
TLS3_k127_8014864_4	504472.Slin_1875	7.733e-45	166.0	COG0526@1|root,COG0526@2|Bacteria,4NQ50@976|Bacteroidetes,47QVC@768503|Cytophagia	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
TLS3_k127_8014864_0	929703.KE386491_gene2405	4.613e-141	459.0	COG2831@1|root,COG2831@2|Bacteria,4PMYI@976|Bacteroidetes,47YEW@768503|Cytophagia	976|Bacteroidetes	U	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
TLS3_k127_8014864_6	616991.JPOO01000001_gene4472	1.211e-16	81.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1HY67@117743|Flavobacteriia	976|Bacteroidetes	P	TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
TLS3_k127_803857_0	1168289.AJKI01000026_gene1376	7.93e-247	780.0	COG3973@1|root,COG3973@2|Bacteria,4NITV@976|Bacteroidetes,2FPMX@200643|Bacteroidia	976|Bacteroidetes	L	COG COG3973 Superfamily I DNA and RNA helicases	helD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2
TLS3_k127_803857_1	1121904.ARBP01000010_gene2392	1.018e-13	74.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_8049724_0	1150600.ADIARSV_1658	0.0	1075.0	COG1523@1|root,COG1523@2|Bacteria,4NIH2@976|Bacteroidetes,1IR47@117747|Sphingobacteriia	976|Bacteroidetes	G	glycogen debranching enzyme GlgX	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
TLS3_k127_8049724_2	1237149.C900_03394	4.754e-85	297.0	COG1449@1|root,COG1449@2|Bacteria,4NFXW@976|Bacteroidetes,47P2J@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 57 family	amyA	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
TLS3_k127_8049724_1	485918.Cpin_5049	2.085e-182	586.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,4NFT6@976|Bacteroidetes,1IQRJ@117747|Sphingobacteriia	976|Bacteroidetes	CE	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
TLS3_k127_8049724_3	1150600.ADIARSV_0422	0.0007843	43.0	COG1597@1|root,COG1597@2|Bacteria,4NKR1@976|Bacteroidetes,1IS4U@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Diacylglycerol kinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
TLS3_k127_8052588_1	1121875.KB907548_gene1381	7.774e-79	276.0	COG0079@1|root,COG0079@2|Bacteria,4NEW8@976|Bacteroidetes,1HXQE@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase, class I	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_8052588_0	1237149.C900_00369	1.629e-165	528.0	COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,47MAZ@768503|Cytophagia	976|Bacteroidetes	E	PFAM aminotransferase class V	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
TLS3_k127_8059294_1	1347342.BN863_21130	1.025e-252	796.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4NEZ5@976|Bacteroidetes,1HYTD@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,F5_F8_type_C,HEAT_2
TLS3_k127_8059294_4	1124780.ANNU01000017_gene1920	5.49e-35	138.0	COG1186@1|root,COG1186@2|Bacteria,4NQ41@976|Bacteroidetes,47R30@768503|Cytophagia	976|Bacteroidetes	J	RF-1 domain	arfB	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
TLS3_k127_8059294_3	1237149.C900_01882	1.007e-54	207.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
TLS3_k127_8059294_2	1267211.KI669560_gene610	1.236e-83	290.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_8059294_0	616991.JPOO01000003_gene39	2.36e-270	850.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
TLS3_k127_806312_0	929556.Solca_1013	0.0	1400.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1INYC@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
TLS3_k127_8072501_2	616991.JPOO01000001_gene4019	6.151e-85	289.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1HX0V@117743|Flavobacteriia	976|Bacteroidetes	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_8072501_0	714943.Mucpa_5522	5.497e-210	665.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1IRMR@117747|Sphingobacteriia	976|Bacteroidetes	J	Amidase	gatA	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
TLS3_k127_8072501_1	929562.Emtol_1230	7.811e-135	435.0	COG0627@1|root,COG0627@2|Bacteria,4NGI8@976|Bacteroidetes,47M5Z@768503|Cytophagia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
TLS3_k127_8072501_4	1121904.ARBP01000012_gene1357	1.122e-54	205.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,47P9B@768503|Cytophagia	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_8072501_5	864702.OsccyDRAFT_0640	3.384e-23	102.0	2E4B4@1|root,32Z6U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8072501_3	1506583.JQJY01000008_gene3814	8.506e-68	237.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,4NFCF@976|Bacteroidetes,1HWJE@117743|Flavobacteriia,2NSE8@237|Flavobacterium	976|Bacteroidetes	P	Transporter	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
TLS3_k127_8082998_4	1250232.JQNJ01000001_gene3316	1.124e-87	303.0	COG1409@1|root,COG1409@2|Bacteria,4NF9K@976|Bacteroidetes,1HY33@117743|Flavobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,MetallophosC,MetallophosN
TLS3_k127_8082998_5	1237149.C900_05879	3.349e-51	184.0	COG0824@1|root,COG0824@2|Bacteria,4NT54@976|Bacteroidetes,47RRM@768503|Cytophagia	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
TLS3_k127_8082998_6	1237149.C900_03996	2.417e-50	181.0	COG1694@1|root,COG1694@2|Bacteria,4NQ3H@976|Bacteroidetes,47QEV@768503|Cytophagia	976|Bacteroidetes	S	PFAM MazG nucleotide pyrophosphohydrolase	ypjD	-	-	-	-	-	-	-	-	-	-	-	MazG
TLS3_k127_8082998_1	504472.Slin_2318	8.281e-185	587.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
TLS3_k127_8082998_0	861299.J421_4478	7.769e-215	679.0	COG1574@1|root,COG1574@2|Bacteria,1ZU9S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
TLS3_k127_8082998_3	1121373.KB903664_gene2550	8.072e-91	304.0	COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,47M1W@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ComB family	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
TLS3_k127_8082998_8	1121129.KB903359_gene2603	3.336e-14	81.0	COG0457@1|root,COG0457@2|Bacteria,4NRB9@976|Bacteroidetes,2FX6X@200643|Bacteroidia,23001@171551|Porphyromonadaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
TLS3_k127_8082998_2	1237149.C900_03998	9.311e-182	574.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,47MN7@768503|Cytophagia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
TLS3_k127_8082998_7	1237149.C900_05487	1.021e-16	87.0	2EG8H@1|root,33A0B@2|Bacteria,4NY1M@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8093445_2	1288963.ADIS_2895	2.957e-30	119.0	COG2755@1|root,COG2755@2|Bacteria,4NQAK@976|Bacteroidetes,47QQ7@768503|Cytophagia	976|Bacteroidetes	E	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
TLS3_k127_8093445_1	1111730.ATTM01000006_gene2632	8.51e-62	219.0	COG0596@1|root,COG0596@2|Bacteria,4PKKR@976|Bacteroidetes,1IJBZ@117743|Flavobacteriia,2NYSA@237|Flavobacterium	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,UPF0227
TLS3_k127_8093445_0	1122176.KB903536_gene1741	2.179e-230	720.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,1IVI6@117747|Sphingobacteriia	976|Bacteroidetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
TLS3_k127_8097049_0	1121875.KB907550_gene626	2.006e-128	415.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1HYSX@117743|Flavobacteriia	976|Bacteroidetes	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
TLS3_k127_8097049_1	1237149.C900_02651	8.873e-125	416.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47X9U@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
TLS3_k127_8101145_5	1267211.KI669560_gene955	4.379e-41	153.0	COG1905@1|root,COG1905@2|Bacteria,4NHIQ@976|Bacteroidetes,1IS1Q@117747|Sphingobacteriia	976|Bacteroidetes	C	NADH-quinone oxidoreductase, E subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
TLS3_k127_8101145_0	926549.KI421517_gene1952	1.199e-238	743.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,47NNF@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
TLS3_k127_8101145_1	153721.MYP_734	8.704e-164	520.0	COG1034@1|root,COG1034@2|Bacteria,4NH3P@976|Bacteroidetes,47K4R@768503|Cytophagia	976|Bacteroidetes	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,NADH-G_4Fe-4S_3
TLS3_k127_8101145_2	153721.MYP_733	5.163e-156	498.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,47K9J@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
TLS3_k127_8101145_3	755732.Fluta_1965	1.429e-80	272.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,1I2F9@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
TLS3_k127_8101145_4	153721.MYP_731	2.842e-48	177.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,47PS7@768503|Cytophagia	976|Bacteroidetes	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
TLS3_k127_8101145_6	1408813.AYMG01000036_gene3290	4.597e-38	145.0	COG0713@1|root,COG0713@2|Bacteria,4NTBP@976|Bacteroidetes,1ISXN@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
TLS3_k127_8101145_7	1408813.AYMG01000036_gene3291	2.087e-21	97.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
TLS3_k127_810120_0	1121904.ARBP01000014_gene133	3.197e-272	851.0	COG0551@1|root,COG2010@1|root,COG0551@2|Bacteria,COG2010@2|Bacteria,4NI4S@976|Bacteroidetes,47M53@768503|Cytophagia	976|Bacteroidetes	CL	Protein of unknown function (DUF1595)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
TLS3_k127_810120_1	1121904.ARBP01000014_gene134	1.281e-98	325.0	COG2960@1|root,COG2960@2|Bacteria,4NFIK@976|Bacteroidetes,47N49@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
TLS3_k127_8104012_2	1237149.C900_04559	2.939e-94	313.0	COG0745@1|root,COG0745@2|Bacteria,4NIQC@976|Bacteroidetes,47PDQ@768503|Cytophagia	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_8104012_1	1121904.ARBP01000004_gene812	3.302e-126	422.0	COG0642@1|root,COG2205@2|Bacteria,4NUBB@976|Bacteroidetes	976|Bacteroidetes	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_8104012_4	243365.CV_3208	2.852e-52	190.0	COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,2VPJM@28216|Betaproteobacteria,2KRKJ@206351|Neisseriales	206351|Neisseriales	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TLS3_k127_8104012_0	1123278.KB893569_gene2317	1.789e-228	713.0	COG2271@1|root,COG2271@2|Bacteria,4NGXW@976|Bacteroidetes,47K8Z@768503|Cytophagia	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_8104012_6	745718.JADT01000017_gene1042	7.749e-25	113.0	COG1266@1|root,COG1266@2|Bacteria,4NVXW@976|Bacteroidetes,1I6MN@117743|Flavobacteriia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
TLS3_k127_8104012_7	745718.JADT01000017_gene1043	1.325e-23	107.0	2C3QT@1|root,32YUW@2|Bacteria,4NWNZ@976|Bacteroidetes,1I6M5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8104012_3	1121875.KB907547_gene3399	1.455e-92	312.0	COG1082@1|root,COG1082@2|Bacteria,4NM4N@976|Bacteroidetes	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_8104012_5	700598.Niako_5915	4.125e-45	167.0	COG5531@1|root,COG5531@2|Bacteria	2|Bacteria	B	SWIB/MDM2 domain	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	SWIB,Topoisom_bac,Toprim,Toprim_Crpt
TLS3_k127_8108400_8	926556.Echvi_1345	1.478e-08	63.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes	976|Bacteroidetes	L	Site-specific recombinase, DNA invertase Pin	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TLS3_k127_8108400_0	1123277.KB893195_gene5662	4.307e-312	970.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47N2K@768503|Cytophagia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
TLS3_k127_8108400_9	1541959.KQ51_00674	1.622e-05	55.0	COG0454@1|root,COG4912@1|root,COG0456@2|Bacteria,COG4912@2|Bacteria	2|Bacteria	L	Dna alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,DNA_alkylation
TLS3_k127_8108400_5	1123278.KB893610_gene4510	4.56e-35	138.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
TLS3_k127_8108400_2	1237149.C900_02169	6.799e-66	234.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,47PIA@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_8108400_6	226186.BT_0219	1.039e-25	110.0	COG3118@1|root,COG3118@2|Bacteria,4NS6N@976|Bacteroidetes,2FT3Z@200643|Bacteroidia,4AR9X@815|Bacteroidaceae	976|Bacteroidetes	O	Psort location Cytoplasmic, score	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
TLS3_k127_8108400_1	1237149.C900_02137	5.363e-68	236.0	COG0558@1|root,COG0558@2|Bacteria,4NHGH@976|Bacteroidetes,47X8N@768503|Cytophagia	976|Bacteroidetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
TLS3_k127_8108400_3	1237149.C900_03078	6.934e-45	168.0	COG4978@1|root,COG4978@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
TLS3_k127_8108400_4	1121930.AQXG01000002_gene2230	1.658e-41	156.0	COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
TLS3_k127_8108400_7	1237149.C900_00306	6.038e-18	85.0	COG4980@1|root,COG4980@2|Bacteria,4NXMW@976|Bacteroidetes,47SQV@768503|Cytophagia	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
TLS3_k127_8115223_3	1123277.KB893228_gene2005	2.043e-21	95.0	COG2334@1|root,COG2334@2|Bacteria,4NGVS@976|Bacteroidetes,47NTM@768503|Cytophagia	976|Bacteroidetes	T	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
TLS3_k127_8115223_2	694427.Palpr_0452	4.008e-28	123.0	2DSNZ@1|root,33GVQ@2|Bacteria,4NYCH@976|Bacteroidetes,2FYX1@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8115223_4	391612.CY0110_09186	1.268e-06	60.0	COG4447@1|root,COG4447@2|Bacteria,1G2KP@1117|Cyanobacteria,3KIGV@43988|Cyanothece	1117|Cyanobacteria	S	PFAM BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
TLS3_k127_8115223_1	926549.KI421517_gene1444	1.604e-40	157.0	COG2353@1|root,COG2353@2|Bacteria,4NMWH@976|Bacteroidetes,47PZ0@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_8115223_0	1237149.C900_04522	5.936e-42	166.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,47M71@768503|Cytophagia	976|Bacteroidetes	T	Signal transduction histidine kinase	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_8121020_2	471854.Dfer_1509	7.821e-42	155.0	COG0477@1|root,COG2814@2|Bacteria,4NG6X@976|Bacteroidetes	976|Bacteroidetes	EGP	Drug resistance transporter Bcr CflA subfamily	bcr	-	-	ko:K03446,ko:K07552	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.2,2.A.1.3	-	-	MFS_1
TLS3_k127_8121020_0	641524.ADICYQ_5776	0.0	1083.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,47K7I@768503|Cytophagia	976|Bacteroidetes	P	Outer membrane receptor for ferrienterochelin and colicins	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_8121020_1	1123008.KB905694_gene1566	1.154e-84	286.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,2FSU3@200643|Bacteroidia,231RU@171551|Porphyromonadaceae	976|Bacteroidetes	KP	Iron dependent repressor, metal binding and dimerisation domain	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
TLS3_k127_8122056_0	1121904.ARBP01000017_gene5109	1.699e-157	502.0	COG5476@1|root,COG5476@2|Bacteria,4NG23@976|Bacteroidetes,47NWD@768503|Cytophagia	976|Bacteroidetes	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
TLS3_k127_8122056_1	362418.IW19_03645	4.945e-50	180.0	COG2259@1|root,COG2259@2|Bacteria,4PMH5@976|Bacteroidetes,1IJSU@117743|Flavobacteriia,2NWE6@237|Flavobacterium	976|Bacteroidetes	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
TLS3_k127_8122056_2	376686.Fjoh_0561	6.651e-21	96.0	2A1V5@1|root,30Q4B@2|Bacteria,4PCH1@976|Bacteroidetes,1ID2W@117743|Flavobacteriia,2NX3R@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8122056_3	1123277.KB893195_gene5625	8.007e-11	64.0	COG2207@1|root,COG2207@2|Bacteria,4NHYH@976|Bacteroidetes,47VC8@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_8126136_0	1237149.C900_05318	2.806e-68	237.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,47MTX@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_8126136_1	1237149.C900_05317	2.361e-67	241.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47N4N@768503|Cytophagia	976|Bacteroidetes	T	PFAM histidine kinase internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_8126136_2	1237149.C900_05315	2.104e-60	213.0	2C9AB@1|root,2ZB91@2|Bacteria,4NKQ3@976|Bacteroidetes,47M3Q@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8127380_2	1123278.KB893545_gene4770	3.651e-70	244.0	COG0394@1|root,COG0394@2|Bacteria,4NE8C@976|Bacteroidetes,47PXK@768503|Cytophagia	976|Bacteroidetes	T	PFAM Low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1,3.1.3.48	ko:K01104,ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
TLS3_k127_8127380_0	1122176.KB903561_gene3599	8.504e-157	501.0	COG0798@1|root,COG0798@2|Bacteria,4NFG7@976|Bacteroidetes,1IP3I@117747|Sphingobacteriia	976|Bacteroidetes	P	arsenical-resistance protein	acr3	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
TLS3_k127_8127380_1	1123057.P872_20420	1.931e-85	286.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes,47JWP@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.53	ko:K00038	ko00140,ko01100,map00140,map01100	-	R04831,R04834,R04844,R04847	RC00139,RC01219,RC01220	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
TLS3_k127_8133475_6	1121904.ARBP01000012_gene1241	2.372e-14	74.0	COG0135@1|root,COG0135@2|Bacteria,4NNQ1@976|Bacteroidetes,47N69@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
TLS3_k127_8133475_2	1124780.ANNU01000065_gene466	6.399e-115	375.0	COG0134@1|root,COG0134@2|Bacteria,4NFJT@976|Bacteroidetes,47JRX@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
TLS3_k127_8133475_1	1237149.C900_03301	2.151e-148	475.0	COG0547@1|root,COG0547@2|Bacteria,4NH2J@976|Bacteroidetes,47KKR@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
TLS3_k127_8133475_4	1434325.AZQN01000011_gene3780	1.775e-79	270.0	COG0512@1|root,COG0512@2|Bacteria,4NE4I@976|Bacteroidetes,47JZQ@768503|Cytophagia	976|Bacteroidetes	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase	pabA	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
TLS3_k127_8133475_5	1239962.C943_04354	4.04e-35	138.0	COG0399@1|root,COG0399@2|Bacteria,4NSX7@976|Bacteroidetes,47SM9@768503|Cytophagia	976|Bacteroidetes	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
TLS3_k127_8133475_0	153721.MYP_1783	3.684e-191	606.0	COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,47JMA@768503|Cytophagia	976|Bacteroidetes	EH	Anthranilate synthase component I, N terminal region	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
TLS3_k127_8133475_3	1121904.ARBP01000001_gene5936	1.877e-83	279.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,47JHJ@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase M13	pepO	-	3.4.24.71	ko:K01415,ko:K07386	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
TLS3_k127_8158_0	1237149.C900_02140	0.0	1137.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,47JHD@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
TLS3_k127_8158_7	880070.Cycma_5076	4.015e-23	105.0	2EN2B@1|root,33FQI@2|Bacteria,4NY51@976|Bacteroidetes,47SN0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8158_1	1237149.C900_03832	6.555e-130	419.0	COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,47K33@768503|Cytophagia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
TLS3_k127_8158_2	1123057.P872_21820	1.67e-116	379.0	COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,47NIJ@768503|Cytophagia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
TLS3_k127_8158_3	1237149.C900_03830	1.379e-109	363.0	COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,47T9B@768503|Cytophagia	976|Bacteroidetes	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
TLS3_k127_8158_4	1237149.C900_03829	2.444e-53	199.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	uspA	-	-	-	-	-	-	-	-	-	-	-	DUF2007,Usp
TLS3_k127_815920_3	1237149.C900_01970	3.892e-38	146.0	COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes,47QHY@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_815920_1	1237149.C900_01971	4.245e-88	300.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47NZ9@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_815920_0	1189612.A33Q_0943	2.652e-153	497.0	COG0591@1|root,COG0591@2|Bacteria,4NH7H@976|Bacteroidetes,47JA4@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K14387	ko04725,ko05231,map04725,map05231	-	-	-	ko00000,ko00001,ko02000	2.A.21,2.A.21.8	-	-	HD_4,SSF
TLS3_k127_815920_2	1121904.ARBP01000001_gene5611	4.232e-56	198.0	COG1765@1|root,COG1765@2|Bacteria,4NNTY@976|Bacteroidetes,47R4T@768503|Cytophagia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
TLS3_k127_815920_4	1480694.DC28_11390	1.298e-31	124.0	COG0626@1|root,COG0626@2|Bacteria,2JBHG@203691|Spirochaetes	203691|Spirochaetes	E	cystathionine	metZ	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
TLS3_k127_817190_0	643867.Ftrac_1407	1.309e-117	380.0	COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,47JX6@768503|Cytophagia	976|Bacteroidetes	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
TLS3_k127_817190_1	1237149.C900_05060	1.409e-105	346.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,47MP4@768503|Cytophagia	976|Bacteroidetes	D	PFAM ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
TLS3_k127_8181837_2	1237149.C900_02467	1.782e-71	245.0	COG5276@1|root,COG5276@2|Bacteria,4NG4W@976|Bacteroidetes,47K9R@768503|Cytophagia	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
TLS3_k127_8181837_0	1237149.C900_02470	1.288e-277	867.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,47KHA@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
TLS3_k127_8181837_1	1237149.C900_02472	1.718e-163	523.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,47MXD@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
TLS3_k127_8183091_1	1189612.A33Q_4141	1.51e-75	260.0	COG0644@1|root,COG0644@2|Bacteria,4NE67@976|Bacteroidetes,47M1U@768503|Cytophagia	976|Bacteroidetes	C	FAD binding domain	fixC	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl,SE,Trp_halogenase
TLS3_k127_8183091_2	643867.Ftrac_1417	1.057e-14	80.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,GerE,Mor,Response_reg,Y_Y_Y
TLS3_k127_8183091_0	1237149.C900_03492	7.28e-110	368.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,47K87@768503|Cytophagia	976|Bacteroidetes	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
TLS3_k127_8183091_3	391603.FBALC1_10182	1.451e-08	57.0	COG1611@1|root,COG2890@1|root,COG1611@2|Bacteria,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,1HXBN@117743|Flavobacteriia	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
TLS3_k127_8187640_1	1237149.C900_01542	2.591e-39	153.0	28NJ0@1|root,2ZBK9@2|Bacteria,4NM9M@976|Bacteroidetes,47PE2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8187640_0	1121373.KB903666_gene1366	4.575e-103	347.0	COG3437@1|root,COG4251@1|root,COG3437@2|Bacteria,COG4251@2|Bacteria,4NI5R@976|Bacteroidetes,47V13@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
TLS3_k127_8197808_6	1408433.JHXV01000020_gene3535	7.223e-05	56.0	COG1572@1|root,COG3266@1|root,COG1572@2|Bacteria,COG3266@2|Bacteria,4NQBS@976|Bacteroidetes,1I3X2@117743|Flavobacteriia	976|Bacteroidetes	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
TLS3_k127_8197808_5	755732.Fluta_2725	1.001e-18	101.0	COG3210@1|root,COG3291@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IKDY@117743|Flavobacteriia,2PC6N@246874|Cryomorphaceae	976|Bacteroidetes	U	SPTR Conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA,SprB
TLS3_k127_8197808_0	926549.KI421517_gene3720	2.18e-302	952.0	COG4206@1|root,COG4206@2|Bacteria,4PKFW@976|Bacteroidetes,47P17@768503|Cytophagia	976|Bacteroidetes	H	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
TLS3_k127_8197808_4	945713.IALB_3191	1.265e-29	124.0	COG3474@1|root,COG3474@2|Bacteria	2|Bacteria	C	electron transfer activity	cyp	-	-	ko:K02305,ko:K08738	ko00910,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00910,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00529,M00595	R00294,R10151	RC02794,RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.10,3.D.4.6	-	-	Cytochrom_C,Cytochrome_P460
TLS3_k127_8197808_2	929713.NIASO_10520	4.473e-43	161.0	COG3832@1|root,COG3832@2|Bacteria,4NQ4A@976|Bacteroidetes	976|Bacteroidetes	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_8197808_1	925409.KI911562_gene2401	2.775e-70	242.0	COG0262@1|root,COG0262@2|Bacteria,4NPJF@976|Bacteroidetes,1J056@117747|Sphingobacteriia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
TLS3_k127_8197808_3	379066.GAU_3151	7.052e-35	140.0	2E0TE@1|root,32WB2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8197808_7	1338011.BD94_2648	0.0005947	49.0	COG4270@1|root,COG4270@2|Bacteria,4NP5F@976|Bacteroidetes,1I4H6@117743|Flavobacteriia,34REV@308865|Elizabethkingia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
TLS3_k127_8201055_3	1150600.ADIARSV_4303	2.345e-50	179.0	COG2308@1|root,COG2308@2|Bacteria,4NFMN@976|Bacteroidetes,1INRP@117747|Sphingobacteriia	976|Bacteroidetes	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
TLS3_k127_8201055_0	714943.Mucpa_2632	2.449e-120	394.0	COG2307@1|root,COG2307@2|Bacteria,4NHIB@976|Bacteroidetes,1IR0B@117747|Sphingobacteriia	976|Bacteroidetes	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
TLS3_k127_8201055_1	700598.Niako_6357	4.151e-119	391.0	COG1305@1|root,COG1305@2|Bacteria,4NF4N@976|Bacteroidetes,1IPWA@117747|Sphingobacteriia	976|Bacteroidetes	E	COGs COG1305 Transglutaminase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
TLS3_k127_8201055_2	269798.CHU_1660	1.274e-50	181.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,47KPX@768503|Cytophagia	976|Bacteroidetes	G	Glucosamine-6-phosphate isomerase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
TLS3_k127_8216687_0	1237149.C900_00918	0.0	1290.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,47K49@768503|Cytophagia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
TLS3_k127_8220426_5	1237149.C900_05943	3.087e-82	276.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,47JH7@768503|Cytophagia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
TLS3_k127_8220426_4	1237149.C900_05942	3.832e-94	314.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,47KG4@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
TLS3_k127_8220426_6	1237149.C900_05941	1.663e-48	180.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,47RVI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8220426_3	1237149.C900_05940	2.499e-124	405.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,47K9I@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
TLS3_k127_8220426_2	1237149.C900_05939	4.483e-128	413.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,47JM3@768503|Cytophagia	976|Bacteroidetes	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
TLS3_k127_8220426_1	1237149.C900_05937	2.094e-194	623.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,47KF7@768503|Cytophagia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
TLS3_k127_8220426_0	1237149.C900_05936	1.4e-296	916.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,47KXM@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
TLS3_k127_825778_1	1279009.ADICEAN_01598	1.41e-140	451.0	COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes,47URP@768503|Cytophagia	976|Bacteroidetes	EH	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_825778_2	869213.JCM21142_93619	6.156e-36	143.0	2AFQQ@1|root,315SK@2|Bacteria,4NJD4@976|Bacteroidetes,47PFM@768503|Cytophagia	976|Bacteroidetes	S	NUMOD4 motif	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3,NUMOD4
TLS3_k127_825778_5	1237149.C900_01373	1.932e-14	78.0	COG0071@1|root,COG0071@2|Bacteria,4NXRP@976|Bacteroidetes,47SZP@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
TLS3_k127_825778_0	1237149.C900_05714	1.068e-189	608.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,47MAI@768503|Cytophagia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_825778_4	1356852.N008_14990	2.626e-19	99.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,47K87@768503|Cytophagia	976|Bacteroidetes	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
TLS3_k127_825778_3	558152.IQ37_02195	4.499e-24	104.0	COG2850@1|root,COG2850@2|Bacteria,4NEJI@976|Bacteroidetes,1HWP6@117743|Flavobacteriia,3ZNTK@59732|Chryseobacterium	976|Bacteroidetes	S	A domain family that is part of the cupin metalloenzyme superfamily.	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
TLS3_k127_8258220_4	1250232.JQNJ01000001_gene2772	2.064e-30	123.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HZG4@117743|Flavobacteriia	976|Bacteroidetes	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
TLS3_k127_8258220_1	388413.ALPR1_19728	9.532e-238	745.0	COG0561@1|root,COG0561@2|Bacteria,4PMMP@976|Bacteroidetes	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
TLS3_k127_8258220_0	388413.ALPR1_19733	0.0	1154.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47Y44@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_8258220_3	1237149.C900_02568	1.633e-134	437.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,47MGC@768503|Cytophagia	976|Bacteroidetes	K	PFAM Periplasmic binding protein LacI transcriptional regulator	cytR	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
TLS3_k127_8258220_2	1237149.C900_04352	2.042e-139	452.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,47NQ6@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
TLS3_k127_8278871_4	1380600.AUYN01000009_gene1069	3.459e-31	126.0	COG0627@1|root,COG0627@2|Bacteria,4NPE4@976|Bacteroidetes	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
TLS3_k127_8278871_2	1123248.KB893325_gene1149	1.981e-201	634.0	COG0412@1|root,COG0412@2|Bacteria,4NIXW@976|Bacteroidetes,1IXE7@117747|Sphingobacteriia	976|Bacteroidetes	Q	COG COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_7,Pec_lyase,Peptidase_S9
TLS3_k127_8278871_0	1123278.KB893444_gene1681	2.975e-249	774.0	COG0673@1|root,COG0673@2|Bacteria,4NF96@976|Bacteroidetes,47KB4@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_8278871_1	485917.Phep_1286	4.774e-223	699.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,1IRDK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
TLS3_k127_8278871_3	1123248.KB893325_gene1150	9.579e-89	296.0	COG0363@1|root,COG0363@2|Bacteria,4NFCM@976|Bacteroidetes,1IUZV@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
TLS3_k127_828423_1	1122621.ATZA01000002_gene1600	1.259e-69	256.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1IPA0@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Family of	-	-	-	-	-	-	-	-	-	-	-	-	TamB
TLS3_k127_828423_3	1237149.C900_05849	9.667e-16	78.0	COG5487@1|root,COG5487@2|Bacteria,4NXPG@976|Bacteroidetes,47T5C@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
TLS3_k127_828423_4	1237149.C900_02112	1.736e-15	82.0	COG5502@1|root,COG5502@2|Bacteria	2|Bacteria	V	conserved protein (DUF2267)	-	-	2.1.1.72	ko:K03427,ko:K06910,ko:K07005	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF2267
TLS3_k127_828423_7	1492738.FEM21_28100	1.09e-06	53.0	COG4980@1|root,COG4980@2|Bacteria,4NRSE@976|Bacteroidetes,1I46Y@117743|Flavobacteriia,2NX2B@237|Flavobacterium	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
TLS3_k127_828423_2	497964.CfE428DRAFT_3996	5.944e-23	99.0	COG3237@1|root,COG3237@2|Bacteria	2|Bacteria	K	CsbD-like	yjbJ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	CsbD
TLS3_k127_828423_0	1237149.C900_05249	1.076e-80	274.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,47PK1@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA,PD40
TLS3_k127_828423_5	1121897.AUGO01000013_gene3302	7.365e-08	56.0	COG3871@1|root,COG3871@2|Bacteria,4NNGC@976|Bacteroidetes,1I1XY@117743|Flavobacteriia,2NWBT@237|Flavobacterium	976|Bacteroidetes	S	general stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyrid_ox_like
TLS3_k127_8287315_0	755732.Fluta_0503	0.0	1111.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,1HZTJ@117743|Flavobacteriia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
TLS3_k127_8287315_1	504472.Slin_5085	2.284e-315	970.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,47KR2@768503|Cytophagia	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
TLS3_k127_8297281_1	1237149.C900_05722	9.13e-102	335.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,47JQJ@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
TLS3_k127_8297281_0	1237149.C900_05721	3.5e-323	1000.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,47KKF@768503|Cytophagia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
TLS3_k127_8297281_3	1237149.C900_05720	9.362e-52	185.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,47Q9C@768503|Cytophagia	976|Bacteroidetes	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
TLS3_k127_8297281_2	1237149.C900_05719	1.252e-62	224.0	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,47MUP@768503|Cytophagia	976|Bacteroidetes	H	PFAM Biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
TLS3_k127_8297281_4	1123248.KB893348_gene332	1.715e-17	83.0	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,1IQEJ@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
TLS3_k127_830668_11	862908.BMS_1123	7.066e-05	46.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,42UMU@68525|delta/epsilon subdivisions,2MSSJ@213481|Bdellovibrionales,2WRRN@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Thi4 family	-	-	-	-	-	-	-	-	-	-	-	-	DAO
TLS3_k127_830668_10	760192.Halhy_4313	9.561e-08	53.0	COG0620@1|root,COG0620@2|Bacteria,4NF5S@976|Bacteroidetes,1IQYW@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
TLS3_k127_830668_3	1185876.BN8_00276	1.872e-132	425.0	COG4821@1|root,COG4821@2|Bacteria,4NHQW@976|Bacteroidetes,47MJI@768503|Cytophagia	976|Bacteroidetes	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
TLS3_k127_830668_6	1123278.KB893499_gene323	5.274e-103	342.0	COG1940@1|root,COG1940@2|Bacteria,4NH8S@976|Bacteroidetes,47J9G@768503|Cytophagia	976|Bacteroidetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
TLS3_k127_830668_4	1089547.KB913013_gene2070	8.913e-117	380.0	COG1028@1|root,COG1028@2|Bacteria,4NJKA@976|Bacteroidetes,47KN3@768503|Cytophagia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_830668_5	1294265.JCM21738_2017	9.088e-104	345.0	COG0673@1|root,COG0673@2|Bacteria,1UZRV@1239|Firmicutes,4HEWB@91061|Bacilli,1ZE5A@1386|Bacillus	91061|Bacilli	S	dehydrogenases and related proteins	ysjB	-	-	ko:K03810	-	-	-	-	ko00000	-	-	-	GFO_IDH_MocA
TLS3_k127_830668_7	1185876.BN8_01934	4.722e-62	218.0	COG2318@1|root,COG2318@2|Bacteria,4NNQA@976|Bacteroidetes,47Q00@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_830668_1	1237149.C900_05293	1.355e-252	801.0	COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_830668_0	760192.Halhy_3755	0.0	1142.0	COG1434@1|root,COG1434@2|Bacteria,4NE96@976|Bacteroidetes,1IQHX@117747|Sphingobacteriia	976|Bacteroidetes	S	Gram-negative-bacterium-type cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM
TLS3_k127_830668_8	641524.ADICYQ_5575	1.723e-53	194.0	COG0457@1|root,COG0457@2|Bacteria,4NRIH@976|Bacteroidetes,47QEH@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
TLS3_k127_830668_2	1123278.KB893433_gene631	1.654e-161	516.0	28K3C@1|root,2Z9SH@2|Bacteria,4NKA2@976|Bacteroidetes,47NBG@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8320660_3	1237149.C900_04581	4.933e-111	369.0	COG2972@1|root,COG2972@2|Bacteria,4NI09@976|Bacteroidetes,47K66@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_8320660_2	1237149.C900_04582	1.085e-120	390.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,47N62@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_8320660_1	926549.KI421517_gene466	7.616e-175	557.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47M9H@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
TLS3_k127_8320660_0	1237149.C900_01785	6.407e-211	662.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,47JPG@768503|Cytophagia	976|Bacteroidetes	F	TIGRFAM dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
TLS3_k127_8320660_6	1237149.C900_01784	5.476e-25	106.0	2EDEU@1|root,337B5@2|Bacteria,4NVH5@976|Bacteroidetes,47SHQ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8320660_7	1223410.KN050846_gene1253	2.582e-23	105.0	2DM52@1|root,32UG7@2|Bacteria,4NSYJ@976|Bacteroidetes,1I4AH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8320660_4	1223410.KN050846_gene1254	5.513e-59	217.0	28JMC@1|root,2Z9DW@2|Bacteria,4NIFI@976|Bacteroidetes,1HXDM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_8320660_5	1137281.D778_01056	8.441e-57	201.0	COG1595@1|root,COG1595@2|Bacteria,4NMCX@976|Bacteroidetes,1I1EN@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_8341870_0	1237149.C900_03858	2.941e-73	250.0	COG0477@1|root,COG2814@2|Bacteria,4NFM7@976|Bacteroidetes,47N08@768503|Cytophagia	976|Bacteroidetes	EGP	Major facilitator superfamily	tetA	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
TLS3_k127_8341870_1	1048983.EL17_02965	1.371e-69	241.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,47P9D@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised protein family UPF0029, Impact, N-terminal	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
TLS3_k127_8341870_3	1227739.Hsw_0214	3.057e-31	134.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,47RTK@768503|Cytophagia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
TLS3_k127_8341870_2	700598.Niako_5904	4.915e-50	184.0	COG2318@1|root,COG2318@2|Bacteria,4NREM@976|Bacteroidetes	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_8342669_1	43989.cce_5070	5.648e-30	120.0	2CCSR@1|root,32RWC@2|Bacteria,1G7HK@1117|Cyanobacteria,3KK3X@43988|Cyanothece	1117|Cyanobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
TLS3_k127_8342669_0	313606.M23134_07780	3.149e-173	554.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia	976|Bacteroidetes	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_8342669_2	1237149.C900_04036	1.043e-07	56.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
TLS3_k127_8344551_1	1313301.AUGC01000021_gene1211	3.637e-44	166.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_8344551_0	1279009.ADICEAN_03351	6.147e-78	293.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4P1E3@976|Bacteroidetes,47TRZ@768503|Cytophagia	976|Bacteroidetes	U	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8344551_2	1121859.KB890756_gene1564	1.974e-18	101.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
TLS3_k127_8350938_0	1121481.AUAS01000001_gene4861	6.759e-224	696.0	COG0673@1|root,COG0673@2|Bacteria,4NG5E@976|Bacteroidetes,47NZU@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_8350938_1	1123248.KB893359_gene2085	1.035e-202	633.0	COG1082@1|root,COG1082@2|Bacteria,4NFSP@976|Bacteroidetes,1IW7J@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_8356194_0	761193.Runsl_0848	5.04e-160	511.0	COG0665@1|root,COG0665@2|Bacteria,4NKQK@976|Bacteroidetes,47Q2W@768503|Cytophagia	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
TLS3_k127_8356194_1	313606.M23134_04898	6.744e-66	231.0	COG1648@1|root,COG1648@2|Bacteria,4NI81@976|Bacteroidetes,47PPT@768503|Cytophagia	976|Bacteroidetes	H	Siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304,ko:K07090	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M,TauE
TLS3_k127_8359845_4	1237149.C900_04012	2.626e-20	92.0	2DQ9W@1|root,335IW@2|Bacteria,4NX9R@976|Bacteroidetes,47SCH@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8359845_3	1237149.C900_04011	8.439e-59	210.0	COG1595@1|root,COG1595@2|Bacteria,4NSVA@976|Bacteroidetes,47QAU@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_8359845_0	1124780.ANNU01000054_gene3525	5.962e-237	737.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,47KGI@768503|Cytophagia	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
TLS3_k127_8359845_2	153721.MYP_4471	6.644e-76	260.0	COG2761@1|root,COG2761@2|Bacteria,4NJ3N@976|Bacteroidetes,47NV7@768503|Cytophagia	976|Bacteroidetes	Q	dithiol-disulfide isomerase involved in polyketide biosynthesis	-	-	5.3.4.1	ko:K01829	-	-	-	-	ko00000,ko01000	-	-	-	DSBA
TLS3_k127_8359845_1	1237149.C900_01850	3.17e-101	338.0	COG4409@1|root,COG4409@2|Bacteria,4NJCZ@976|Bacteroidetes	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TLS3_k127_8370396_5	1267533.KB906733_gene3447	1.998e-57	225.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
TLS3_k127_8370396_7	1279009.ADICEAN_02104	7.066e-05	46.0	COG5395@1|root,COG5395@2|Bacteria,4NSVW@976|Bacteroidetes,47XVK@768503|Cytophagia	976|Bacteroidetes	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
TLS3_k127_8370396_4	1121904.ARBP01000001_gene5410	2.013e-61	220.0	COG2318@1|root,COG2318@2|Bacteria,4NGXE@976|Bacteroidetes,47RA5@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
TLS3_k127_8370396_0	1120951.AUBG01000006_gene517	5.859e-155	506.0	COG0457@1|root,COG0457@2|Bacteria,4NFMI@976|Bacteroidetes,1HZPZ@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
TLS3_k127_8370396_2	335283.Neut_1347	1.756e-88	298.0	COG3826@1|root,COG3826@2|Bacteria,1MWVV@1224|Proteobacteria,2VHMX@28216|Betaproteobacteria,37332@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Oxygenase, catalysing oxidative methylation of damaged DNA	-	-	-	ko:K09990	-	-	-	-	ko00000	-	-	-	Oxygenase-NA
TLS3_k127_8370396_6	1338011.BD94_1312	1.256e-22	99.0	COG2169@1|root,COG2169@2|Bacteria,4NV90@976|Bacteroidetes,1I5VR@117743|Flavobacteriia,34RQW@308865|Elizabethkingia	976|Bacteroidetes	F	Metal binding domain of Ada	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding
TLS3_k127_8370396_3	1042377.AFPJ01000051_gene33	6.685e-76	264.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_8370396_1	929556.Solca_1220	1.762e-108	359.0	COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,4NFYC@976|Bacteroidetes,1IP7V@117747|Sphingobacteriia	976|Bacteroidetes	K	6-O-methylguanine DNA methyltransferase, DNA binding domain	ada	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18,Methyltransf_1N
TLS3_k127_8389817_0	1237149.C900_05294	1.283e-243	775.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_8389817_1	1237149.C900_05293	1.516e-230	737.0	COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_8397850_2	1124780.ANNU01000052_gene3573	1.513e-34	144.0	COG1283@1|root,COG1283@2|Bacteria,4NMSG@976|Bacteroidetes,47UEZ@768503|Cytophagia	976|Bacteroidetes	P	Na+/Pi-cotransporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_Pi_cotrans
TLS3_k127_8397850_4	1121129.KB903359_gene1708	3.535e-05	51.0	2E0ZK@1|root,32WFU@2|Bacteria,4NTTI@976|Bacteroidetes,2FUB3@200643|Bacteroidia,22YHR@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
TLS3_k127_8397850_0	1124780.ANNU01000052_gene3570	4.085e-93	312.0	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,47MXM@768503|Cytophagia	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
TLS3_k127_8397850_1	926549.KI421517_gene773	2.361e-54	194.0	COG2318@1|root,COG2318@2|Bacteria,4NN7V@976|Bacteroidetes,47QXV@768503|Cytophagia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
TLS3_k127_8412526_4	743722.Sph21_3041	2.726e-19	87.0	COG3081@1|root,COG3081@2|Bacteria,4NFSN@976|Bacteroidetes,1IPSX@117747|Sphingobacteriia	976|Bacteroidetes	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
TLS3_k127_8412526_3	880071.Fleli_0342	1.208e-22	103.0	2AMB7@1|root,31C6A@2|Bacteria,4NQ8I@976|Bacteroidetes,47Q46@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8412526_1	1237149.C900_01781	1.194e-97	325.0	COG1512@1|root,COG1512@2|Bacteria	2|Bacteria	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8412526_2	1237149.C900_03458	1.21e-58	212.0	COG0596@1|root,COG0596@2|Bacteria,4PKUD@976|Bacteroidetes,47Y3M@768503|Cytophagia	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
TLS3_k127_8412526_0	1237149.C900_03459	1.174e-233	726.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,47JUB@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
TLS3_k127_8416313_2	1279009.ADICEAN_01345	4.962e-116	381.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,47MGR@768503|Cytophagia	976|Bacteroidetes	EF	Ribose-phosphate pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
TLS3_k127_8416313_4	1121904.ARBP01000006_gene4069	7.919e-32	133.0	28P2C@1|root,2ZBYG@2|Bacteria,4NMEQ@976|Bacteroidetes,47PKX@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8416313_1	1185876.BN8_00013	2.767e-125	409.0	COG1735@1|root,COG1735@2|Bacteria,4NJYF@976|Bacteroidetes,47NZQ@768503|Cytophagia	976|Bacteroidetes	S	Phosphotriesterase family	php	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
TLS3_k127_8416313_3	485918.Cpin_1650	4.908e-86	290.0	COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,1IQCX@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
TLS3_k127_8416313_0	498211.CJA_0127	7.497e-145	483.0	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,1FI4C@10|Cellvibrio	1236|Gammaproteobacteria	M	Insecticide toxin TcdB middle/N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
TLS3_k127_8425440_2	1279009.ADICEAN_00180	8.919e-25	104.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,47KH2@768503|Cytophagia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_8425440_0	1237149.C900_03186	1.544e-72	250.0	COG0526@1|root,COG0526@2|Bacteria,4PKPR@976|Bacteroidetes,47PBI@768503|Cytophagia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TLS3_k127_8425440_1	1237149.C900_03187	1.301e-54	196.0	COG0526@1|root,COG0526@2|Bacteria,4NQ9U@976|Bacteroidetes,47RGU@768503|Cytophagia	976|Bacteroidetes	CO	Thioredoxin	trxC	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin,Thioredoxin_8
TLS3_k127_8444060_1	655815.ZPR_4217	3.591e-75	259.0	COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,1HXRT@117743|Flavobacteriia	976|Bacteroidetes	P	membrane protein TerC	terC	-	-	-	-	-	-	-	-	-	-	-	TerC
TLS3_k127_8444060_2	927658.AJUM01000043_gene683	1.101e-57	205.0	COG3476@1|root,COG3476@2|Bacteria,4NP0D@976|Bacteroidetes,2FT5H@200643|Bacteroidia	976|Bacteroidetes	T	TspO/MBR family	tspO	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
TLS3_k127_8444060_0	509635.N824_11870	3.165e-134	439.0	COG0665@1|root,COG0665@2|Bacteria,4NFT6@976|Bacteroidetes,1IR0J@117747|Sphingobacteriia	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
TLS3_k127_844478_1	1121904.ARBP01000001_gene5783	1.53e-80	276.0	COG3011@1|root,COG3011@2|Bacteria,4NN81@976|Bacteroidetes,47XU9@768503|Cytophagia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
TLS3_k127_844478_0	762903.Pedsa_1291	6.32e-122	398.0	COG1090@1|root,COG1090@2|Bacteria,4NH8J@976|Bacteroidetes,1IPH3@117747|Sphingobacteriia	976|Bacteroidetes	S	NAD dependent epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
TLS3_k127_844478_4	525373.HMPREF0766_13387	2.968e-48	177.0	COG4276@1|root,COG4276@2|Bacteria,4NQ3V@976|Bacteroidetes,1IT4R@117747|Sphingobacteriia	976|Bacteroidetes	S	Cell division protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_844478_3	1237149.C900_05477	8.642e-64	223.0	COG1595@1|root,COG1595@2|Bacteria,4NMYQ@976|Bacteroidetes,47PII@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_844478_5	1237149.C900_05478	8.364e-45	172.0	COG1413@1|root,COG1413@2|Bacteria,4NY24@976|Bacteroidetes	976|Bacteroidetes	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
TLS3_k127_844478_2	1121285.AUFK01000001_gene2007	8.104e-66	233.0	COG3595@1|root,COG3595@2|Bacteria,4NKSN@976|Bacteroidetes,1I2JR@117743|Flavobacteriia,3ZTIE@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
TLS3_k127_8447237_0	1237149.C900_05660	5.271e-158	503.0	COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,47JNS@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
TLS3_k127_8447237_1	1237149.C900_05659	2.007e-60	211.0	COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,47Q7A@768503|Cytophagia	976|Bacteroidetes	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
TLS3_k127_8460289_1	1237149.C900_02229	1.036e-77	267.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,47PU4@768503|Cytophagia	976|Bacteroidetes	M	Cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
TLS3_k127_8460289_0	1237149.C900_02230	1.815e-83	284.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,47KY0@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_8460996_3	1233950.IW22_24210	1.032e-06	53.0	COG2207@1|root,COG2207@2|Bacteria,4PIWS@976|Bacteroidetes,1IGN8@117743|Flavobacteriia,3ZTM8@59732|Chryseobacterium	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_8460996_1	313596.RB2501_12237	7.406e-23	101.0	2CFVG@1|root,3346Y@2|Bacteria,4NVFV@976|Bacteroidetes,1I55C@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8460996_2	388413.ALPR1_11895	2.238e-17	87.0	2DPVN@1|root,32UMW@2|Bacteria,4P43W@976|Bacteroidetes	976|Bacteroidetes	I	Acyl-CoA cholesterol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8460996_0	1042326.AZNV01000031_gene3669	2.081e-215	678.0	COG0366@1|root,COG0366@2|Bacteria,1PDXT@1224|Proteobacteria,2UQIK@28211|Alphaproteobacteria,4BIGR@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	alpha amylase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
TLS3_k127_8463559_3	946077.W5A_08949	1.779e-47	175.0	COG2318@1|root,COG2318@2|Bacteria,4NNQI@976|Bacteroidetes,1I28A@117743|Flavobacteriia	976|Bacteroidetes	S	DinB superfamily	yfiT	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_8463559_2	1237149.C900_05312	6.206e-80	273.0	COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,47MB3@768503|Cytophagia	976|Bacteroidetes	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
TLS3_k127_8463559_0	1237149.C900_04422	1.849e-146	478.0	28KMN@1|root,2ZA61@2|Bacteria,4NJ9P@976|Bacteroidetes,47P0N@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062
TLS3_k127_8463559_1	1237149.C900_04420	6.557e-88	301.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4P15I@976|Bacteroidetes,47X8A@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
TLS3_k127_8465478_2	388413.ALPR1_03545	5.563e-36	139.0	COG3091@1|root,COG3091@2|Bacteria,4NDXX@976|Bacteroidetes,47QAA@768503|Cytophagia	976|Bacteroidetes	S	PFAM SprT-like family	sprT	-	-	-	-	-	-	-	-	-	-	-	SprT-like
TLS3_k127_8465478_0	1279009.ADICEAN_02693	1.011e-199	631.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,47K6M@768503|Cytophagia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
TLS3_k127_8465478_1	1124780.ANNU01000017_gene1972	2.316e-111	367.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,47K35@768503|Cytophagia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
TLS3_k127_8472287_3	1237149.C900_01308	6.321e-43	159.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_8472287_0	929556.Solca_0108	2.608e-207	658.0	COG0457@1|root,COG0457@2|Bacteria,4NFMI@976|Bacteroidetes,1IV5V@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
TLS3_k127_8472287_2	761193.Runsl_5573	2.448e-47	181.0	COG4757@1|root,COG4757@2|Bacteria,4NJ3M@976|Bacteroidetes,47QI5@768503|Cytophagia	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
TLS3_k127_8472287_1	1250232.JQNJ01000001_gene1549	3.006e-109	382.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1HZEZ@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HTH_18,HisKA,Response_reg,TPR_12,TPR_8
TLS3_k127_8474480_1	1185876.BN8_03758	2.543e-228	717.0	COG4198@1|root,COG4198@2|Bacteria,4NEQC@976|Bacteroidetes,47M3E@768503|Cytophagia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_2
TLS3_k127_8474480_0	471854.Dfer_1098	0.0	1557.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47M35@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_8474480_5	1042376.AFPK01000063_gene1139	4.938e-32	132.0	COG1396@1|root,COG3837@1|root,COG1396@2|Bacteria,COG3837@2|Bacteria,4NN23@976|Bacteroidetes,1I1NN@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
TLS3_k127_8474480_3	1121373.KB903662_gene233	2.012e-115	385.0	COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,47SEI@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
TLS3_k127_8474480_2	153721.MYP_329	8.464e-169	540.0	COG1449@1|root,COG1449@2|Bacteria,4NFXW@976|Bacteroidetes,47P2J@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 57 family	amyA	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
TLS3_k127_8474480_4	1173026.Glo7428_4949	1.348e-35	137.0	COG0665@1|root,COG0665@2|Bacteria,1G3TS@1117|Cyanobacteria	1117|Cyanobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
TLS3_k127_8485233_1	1185876.BN8_06423	2.963e-40	150.0	COG0496@1|root,COG0496@2|Bacteria,4NGJN@976|Bacteroidetes,47M32@768503|Cytophagia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	-	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
TLS3_k127_8485233_0	616991.JPOO01000003_gene1775	1.882e-133	436.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1HX2N@117743|Flavobacteriia,23FRX@178469|Arenibacter	976|Bacteroidetes	S	Peptidase dimerisation domain	amaA	-	3.5.1.32	ko:K01436,ko:K01451	ko00360,map00360	-	R01424	RC00096,RC00162	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_8485233_2	468059.AUHA01000003_gene2007	1.625e-07	61.0	2D42T@1|root,32TG5@2|Bacteria,4NT28@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8499245_2	1237149.C900_00528	2.04e-79	269.0	COG0664@1|root,COG0664@2|Bacteria,4NKW5@976|Bacteroidetes,47N83@768503|Cytophagia	976|Bacteroidetes	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TLS3_k127_8499245_0	1492738.FEM21_03840	9.986e-84	286.0	COG3217@1|root,COG3217@2|Bacteria,4NG33@976|Bacteroidetes,1I42J@117743|Flavobacteriia,2NUWH@237|Flavobacterium	976|Bacteroidetes	S	PFAM MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
TLS3_k127_8499245_3	1237149.C900_00530	3.667e-64	224.0	COG1981@1|root,COG1981@2|Bacteria,4NEWG@976|Bacteroidetes,47PXS@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
TLS3_k127_8499245_1	1237149.C900_00531	2.185e-82	280.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,47NK1@768503|Cytophagia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
TLS3_k127_8499245_4	1048983.EL17_06715	4.938e-10	63.0	COG2010@1|root,COG2010@2|Bacteria,4NTWV@976|Bacteroidetes,47REP@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c, class I	aniA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
TLS3_k127_8514449_2	313628.LNTAR_01957	3.599e-19	89.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
TLS3_k127_8514449_0	143224.JQMD01000002_gene78	1.778e-124	403.0	COG1082@1|root,COG1082@2|Bacteria,4NHMP@976|Bacteroidetes,1I6H6@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
TLS3_k127_8514449_1	485917.Phep_1339	6.885e-98	327.0	COG1028@1|root,COG1028@2|Bacteria,4NHDB@976|Bacteroidetes,1INQP@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_8515931_2	313612.L8106_18562	1.58e-40	155.0	COG2940@1|root,COG2940@2|Bacteria,1G6XB@1117|Cyanobacteria,1HCEZ@1150|Oscillatoriales	1117|Cyanobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
TLS3_k127_8515931_4	1168034.FH5T_12510	1.799e-18	94.0	2E9C0@1|root,333JQ@2|Bacteria,4NVAR@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8515931_0	926549.KI421517_gene1091	2.242e-169	536.0	COG2730@1|root,COG2730@2|Bacteria,4NIBG@976|Bacteroidetes,47P3X@768503|Cytophagia	976|Bacteroidetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase
TLS3_k127_8515931_3	694427.Palpr_1114	3.342e-26	121.0	COG3292@1|root,COG3292@2|Bacteria,4NI2T@976|Bacteroidetes,2FV1K@200643|Bacteroidia,22Z9F@171551|Porphyromonadaceae	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop,YceI
TLS3_k127_8515931_1	1346330.M472_13560	5.8e-143	465.0	COG1757@1|root,COG1757@2|Bacteria,4NFF8@976|Bacteroidetes,1IXHV@117747|Sphingobacteriia	976|Bacteroidetes	C	Na+/H+ antiporter family	mleN	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
TLS3_k127_8515931_5	1379270.AUXF01000001_gene2079	8.864e-06	48.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABM,DUF3225,DUF4440,SnoaL_2,SnoaL_3
TLS3_k127_8519517_0	1237149.C900_02971	7.691e-121	396.0	COG0739@1|root,COG0739@2|Bacteria,4NKR5@976|Bacteroidetes,47X5D@768503|Cytophagia	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_8519517_1	1185876.BN8_00258	4.879e-83	291.0	28I8D@1|root,2Z8B7@2|Bacteria,4NM23@976|Bacteroidetes,47NIB@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
TLS3_k127_8519517_2	313606.M23134_00208	9.038e-56	207.0	COG3595@1|root,COG3595@2|Bacteria,4NJCC@976|Bacteroidetes,47MIA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
TLS3_k127_8519517_3	1550091.JROE01000008_gene3339	1.483e-10	63.0	COG3832@1|root,COG3832@2|Bacteria,4NQ55@976|Bacteroidetes,1IY1H@117747|Sphingobacteriia	976|Bacteroidetes	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_8519723_3	1124780.ANNU01000045_gene2308	3.05e-27	111.0	COG0682@1|root,COG0682@2|Bacteria,4NFP7@976|Bacteroidetes,47KQC@768503|Cytophagia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
TLS3_k127_8519723_0	153721.MYP_3805	1.234e-239	754.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,4NHXQ@976|Bacteroidetes,47JFU@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
TLS3_k127_8519723_1	1237149.C900_01621	1.571e-86	292.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,47K17@768503|Cytophagia	976|Bacteroidetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
TLS3_k127_8519723_2	1227739.Hsw_0745	2.363e-36	138.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,47MQI@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_8519977_0	411477.PARMER_02796	9.939e-296	917.0	COG1053@1|root,COG1053@2|Bacteria,4NG56@976|Bacteroidetes,2FNK8@200643|Bacteroidia,22YF8@171551|Porphyromonadaceae	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
TLS3_k127_8519977_1	471854.Dfer_4710	6.495e-290	905.0	COG2081@1|root,COG2081@2|Bacteria,4PMNY@976|Bacteroidetes,47Y8Z@768503|Cytophagia	976|Bacteroidetes	S	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
TLS3_k127_8519977_2	1178825.ALIH01000001_gene2651	9.103e-97	325.0	COG2207@1|root,COG2207@2|Bacteria,4NGWC@976|Bacteroidetes,1I08M@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_8519977_3	1123276.KB893275_gene2320	7.631e-76	267.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,47M2K@768503|Cytophagia	976|Bacteroidetes	I	PFAM Phosphatidic acid phosphatase type 2 haloperoxidase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
TLS3_k127_8524080_1	1122179.KB890419_gene54	2.403e-14	75.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
TLS3_k127_8524080_0	1279009.ADICEAN_01862	1.377e-218	698.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47KYY@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_852517_0	223926.28807741	8.933e-262	816.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,1XT97@135623|Vibrionales	135623|Vibrionales	G	Belongs to the GPI family	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
TLS3_k127_8542941_5	929703.KE386491_gene483	6.155e-71	256.0	COG0642@1|root,COG3292@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47Y2E@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator three Y domain protein	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Reg_prop,Response_reg,Y_Y_Y
TLS3_k127_8542941_2	1123248.KB893348_gene225	7.296e-146	481.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1IRJZ@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_9,Reg_prop,Response_reg,Y_Y_Y
TLS3_k127_8542941_8	1123248.KB893348_gene224	3.619e-41	159.0	2E3FB@1|root,32YE4@2|Bacteria,4P77I@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8542941_9	866536.Belba_2801	0.0007529	46.0	COG2198@1|root,COG2198@2|Bacteria,4P5K9@976|Bacteroidetes,47VPC@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8542941_1	1121904.ARBP01000011_gene1486	5.901e-151	489.0	COG0673@1|root,COG0673@2|Bacteria,4NGPP@976|Bacteroidetes,47N04@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
TLS3_k127_8542941_0	468059.AUHA01000002_gene237	2.238e-290	900.0	COG1132@1|root,COG1132@2|Bacteria,4NEBS@976|Bacteroidetes,1IPIB@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS3_k127_8542941_3	269798.CHU_2355	9.761e-136	441.0	COG4307@1|root,COG4307@2|Bacteria,4NFG6@976|Bacteroidetes,47NT7@768503|Cytophagia	976|Bacteroidetes	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
TLS3_k127_8542941_7	1123248.KB893370_gene5032	1.436e-56	198.0	COG3795@1|root,COG3795@2|Bacteria,4NQPY@976|Bacteroidetes,1IYMH@117747|Sphingobacteriia	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
TLS3_k127_8542941_4	700598.Niako_1979	1.506e-95	317.0	COG4941@1|root,COG4941@2|Bacteria,4NGCS@976|Bacteroidetes,1IRPG@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM RNA polymerase sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_8543724_0	925409.KI911562_gene2351	0.0	1501.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPE6@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
TLS3_k127_8543724_1	761193.Runsl_0896	1.317e-127	419.0	COG0845@1|root,COG0845@2|Bacteria,4NIDC@976|Bacteroidetes,47M9U@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
TLS3_k127_8543724_2	471854.Dfer_0042	7.049e-36	138.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,47JA0@768503|Cytophagia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_8544040_0	1237149.C900_03440	7.48e-146	467.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,47JCG@768503|Cytophagia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
TLS3_k127_8544040_1	1237149.C900_03441	2.571e-82	284.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,47K52@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
TLS3_k127_8544040_2	1237149.C900_03442	2.738e-78	276.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,47KXU@768503|Cytophagia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,fn3_3
TLS3_k127_8545673_0	1121904.ARBP01000012_gene1305	2.678e-146	473.0	COG0438@1|root,COG0438@2|Bacteria,4NIP2@976|Bacteroidetes,47MWD@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_8545673_2	1237149.C900_02441	5.352e-75	262.0	COG0463@1|root,COG0463@2|Bacteria,4PPKA@976|Bacteroidetes,47YP2@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_8545673_1	1121904.ARBP01000012_gene1310	1.16e-128	414.0	COG1208@1|root,COG1208@2|Bacteria,4NG3V@976|Bacteroidetes,47M37@768503|Cytophagia	976|Bacteroidetes	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	rfbF	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
TLS3_k127_8547238_1	509635.N824_14415	3.164e-95	314.0	COG4977@1|root,COG4977@2|Bacteria,4NGSR@976|Bacteroidetes,1IP57@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
TLS3_k127_8547238_2	485918.Cpin_4167	9.166e-66	228.0	COG2318@1|root,COG2318@2|Bacteria,4NNMT@976|Bacteroidetes,1IXUX@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
TLS3_k127_8547238_0	504472.Slin_6373	1.054e-182	581.0	COG0277@1|root,COG0277@2|Bacteria,4NGC5@976|Bacteroidetes,47MIC@768503|Cytophagia	976|Bacteroidetes	C	D-arabinono-1,4-lactone oxidase	-	-	1.1.3.41	ko:K00594	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R07152,R11620	RC00108,RC00133	ko00000,ko00001,ko01000	-	-	-	ALO,FAD_binding_4
TLS3_k127_854944_3	1178825.ALIH01000004_gene2923	1.232e-70	243.0	COG2318@1|root,COG2318@2|Bacteria,4NP2C@976|Bacteroidetes,1I23S@117743|Flavobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_854944_0	485917.Phep_3343	0.0	1226.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,4NEK3@976|Bacteroidetes,1INMR@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8
TLS3_k127_854944_2	485917.Phep_3849	1.671e-75	265.0	COG1409@1|root,COG1409@2|Bacteria,4NF8E@976|Bacteroidetes,1ITM2@117747|Sphingobacteriia	976|Bacteroidetes	S	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1,SASA
TLS3_k127_854944_1	1173024.KI912148_gene4897	1.094e-244	814.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1JK4Q@1189|Stigonemataceae	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_854944_4	1202532.FF52_19875	3.432e-19	89.0	COG0745@1|root,COG0745@2|Bacteria,4NXE8@976|Bacteroidetes,1IIY7@117743|Flavobacteriia,2NWJG@237|Flavobacterium	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_8555688_1	1237149.C900_04748	5.832e-123	413.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,47JRI@768503|Cytophagia	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
TLS3_k127_8555688_2	153721.MYP_534	6.595e-107	357.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,47M44@768503|Cytophagia	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
TLS3_k127_8555688_0	1237149.C900_04750	1.451e-143	463.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,47JGH@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
TLS3_k127_8562926_0	985255.APHJ01000021_gene1619	2.372e-74	260.0	2C8CV@1|root,2Z8NV@2|Bacteria,4NH60@976|Bacteroidetes,1HZCW@117743|Flavobacteriia,2P634@244698|Gillisia	976|Bacteroidetes	S	Protein of unknown function (DUF3095)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3095
TLS3_k127_8562926_1	471854.Dfer_4010	1.312e-29	127.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,47KTA@768503|Cytophagia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
TLS3_k127_8564883_3	1123248.KB893337_gene2450	3.194e-178	564.0	COG0673@1|root,COG0673@2|Bacteria,4NFGY@976|Bacteroidetes,1IVQN@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_8564883_5	1124780.ANNU01000016_gene1843	2.23e-147	484.0	COG2197@1|root,COG2197@2|Bacteria,4PKZT@976|Bacteroidetes,47MMK@768503|Cytophagia	976|Bacteroidetes	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8564883_8	376686.Fjoh_4606	3.615e-79	274.0	COG0596@1|root,COG0596@2|Bacteria,4NPF5@976|Bacteroidetes,1IGNY@117743|Flavobacteriia,2NYP1@237|Flavobacterium	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
TLS3_k127_8564883_6	1237149.C900_05853	3.721e-83	279.0	COG2065@1|root,COG2065@2|Bacteria,4NFI1@976|Bacteroidetes,47MTK@768503|Cytophagia	976|Bacteroidetes	F	Pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
TLS3_k127_8564883_4	866536.Belba_1946	1.202e-172	544.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,47KS2@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
TLS3_k127_8564883_1	1237149.C900_05850	2.753e-245	763.0	COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,47K1B@768503|Cytophagia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
TLS3_k127_8564883_9	1237149.C900_05848	7.077e-62	232.0	COG0457@1|root,COG3437@1|root,COG0457@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	2.7.13.3,2.7.7.65,4.6.1.1	ko:K01768,ko:K03415,ko:K07777,ko:K18967	ko00230,ko02020,ko02025,ko02030,ko04113,ko04213,map00230,map02020,map02025,map02030,map04113,map04213	M00478,M00506,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035	9.B.34.1.1	-	-	5TM-5TMR_LYT,CheW,GGDEF,PAS_3,PAS_9,Response_reg
TLS3_k127_8564883_7	1237149.C900_01882	1.645e-80	284.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
TLS3_k127_8564883_0	1237149.C900_01880	2.645e-301	943.0	COG4953@1|root,COG4953@2|Bacteria,4NEG5@976|Bacteroidetes,47KYC@768503|Cytophagia	976|Bacteroidetes	M	penicillin-binding protein 1C	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
TLS3_k127_8564883_2	1237149.C900_05488	1.059e-243	768.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,47MDC@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
TLS3_k127_8568129_1	1237149.C900_03781	1.466e-84	284.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,47JHC@768503|Cytophagia	976|Bacteroidetes	F	Orotidine 5''-phosphate decarboxylase	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
TLS3_k127_8568129_0	1237149.C900_03782	1.04e-146	476.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,47KPJ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
TLS3_k127_8568129_2	1121904.ARBP01000002_gene7210	6.825e-22	100.0	28ICP@1|root,32QUE@2|Bacteria,4NR8Q@976|Bacteroidetes,47QZP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8568364_3	385682.AFSL01000008_gene2577	1.003e-11	68.0	COG1352@1|root,COG1352@2|Bacteria,4NJ75@976|Bacteroidetes,2G228@200643|Bacteroidia,3XJ3U@558415|Marinilabiliaceae	976|Bacteroidetes	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
TLS3_k127_8568364_1	1150469.RSPPHO_00459	2.09e-93	333.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2JQ7J@204441|Rhodospirillales	204441|Rhodospirillales	NT	Four helix bundle sensory module for signal transduction	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
TLS3_k127_8568364_2	153721.MYP_4869	4.811e-31	127.0	COG0835@1|root,COG0835@2|Bacteria,4NTK7@976|Bacteroidetes,47X59@768503|Cytophagia	976|Bacteroidetes	NT	Two component signalling adaptor domain	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
TLS3_k127_8568364_0	153721.MYP_4868	2.208e-110	377.0	COG0643@1|root,COG0643@2|Bacteria,4NG31@976|Bacteroidetes,47MM7@768503|Cytophagia	976|Bacteroidetes	NT	Signal transducing histidine kinase, homodimeric domain	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
TLS3_k127_8569813_3	700598.Niako_3660	1.526e-151	482.0	COG3347@1|root,COG4221@1|root,COG3347@2|Bacteria,COG4221@2|Bacteria,4NEM0@976|Bacteroidetes,1IQ2J@117747|Sphingobacteriia	976|Bacteroidetes	IQ	rhamnulose-1-phosphate aldolase alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
TLS3_k127_8569813_13	1237149.C900_05495	4.882e-51	190.0	COG3714@1|root,COG3714@2|Bacteria,4NMZ9@976|Bacteroidetes,47RZ2@768503|Cytophagia	976|Bacteroidetes	S	PFAM YhhN-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
TLS3_k127_8569813_5	1124780.ANNU01000005_gene2460	2.813e-124	410.0	COG0477@1|root,COG2814@2|Bacteria,4NE7F@976|Bacteroidetes,47MD0@768503|Cytophagia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_8569813_2	1237149.C900_05493	3.379e-159	508.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,47KHU@768503|Cytophagia	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TLS3_k127_8569813_14	1338011.BD94_2428	8.252e-05	53.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,1I34P@117743|Flavobacteriia,34PVP@308865|Elizabethkingia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
TLS3_k127_8569813_7	1237149.C900_05490	3.565e-82	277.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,47P8Y@768503|Cytophagia	976|Bacteroidetes	S	PFAM Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
TLS3_k127_8569813_6	1237149.C900_05489	1.42e-120	390.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,47KDU@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_8569813_12	1237149.C900_01864	1.333e-72	254.0	COG1073@1|root,COG1073@2|Bacteria,4NGDK@976|Bacteroidetes,47Q3Y@768503|Cytophagia	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4
TLS3_k127_8569813_9	997296.PB1_13534	5.114e-76	262.0	COG3332@1|root,COG3332@2|Bacteria,1UYHE@1239|Firmicutes,4HCA1@91061|Bacilli,1ZCCC@1386|Bacillus	91061|Bacilli	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
TLS3_k127_8569813_8	1185876.BN8_06555	7.831e-80	271.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,47KXS@768503|Cytophagia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
TLS3_k127_8569813_10	1237149.C900_01858	4.048e-74	254.0	COG0494@1|root,COG0494@2|Bacteria,4NMHV@976|Bacteroidetes,47P7M@768503|Cytophagia	976|Bacteroidetes	L	pfam nudix	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_8569813_4	1237149.C900_01857	7.563e-149	483.0	COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,47KYV@768503|Cytophagia	976|Bacteroidetes	V	efflux protein, MATE family	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
TLS3_k127_8569813_11	929703.KE386491_gene3243	3.702e-73	250.0	COG1607@1|root,COG1607@2|Bacteria,4NMK1@976|Bacteroidetes,47N9Z@768503|Cytophagia	976|Bacteroidetes	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
TLS3_k127_8569813_1	1121104.AQXH01000003_gene415	1.479e-190	603.0	COG0006@1|root,COG0006@2|Bacteria,4NF0F@976|Bacteroidetes,1IV0D@117747|Sphingobacteriia	976|Bacteroidetes	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
TLS3_k127_8569813_0	1237149.C900_05632	0.0	1031.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,47K9M@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
TLS3_k127_8572630_1	1189612.A33Q_0736	4.341e-216	686.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,47JQI@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS3_k127_8572630_0	1237149.C900_03963	7.629e-218	690.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,47JNN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
TLS3_k127_8572630_7	1237149.C900_03962	5.428e-35	135.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,47R60@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
TLS3_k127_8572630_2	1124780.ANNU01000073_gene715	7.977e-156	501.0	COG1208@1|root,COG1208@2|Bacteria,4PM6W@976|Bacteroidetes,47MB6@768503|Cytophagia	976|Bacteroidetes	JM	Sugar nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,NTP_transf_4
TLS3_k127_8572630_3	1237149.C900_03960	3.415e-122	402.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,47XWD@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase III, delta' subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
TLS3_k127_8572630_5	929562.Emtol_1505	4.302e-106	353.0	COG0181@1|root,COG0181@2|Bacteria,4NHH4@976|Bacteroidetes,47M9Y@768503|Cytophagia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
TLS3_k127_8572630_6	1237149.C900_03958	1.741e-87	297.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,47MY6@768503|Cytophagia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
TLS3_k127_8572630_4	1237149.C900_03957	2.517e-114	375.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,47MQV@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
TLS3_k127_8573201_3	1270196.JCKI01000002_gene510	1.094e-106	353.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_8573201_1	1380384.JADN01000007_gene1614	1.842e-172	547.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,4NENP@976|Bacteroidetes,1HWUM@117743|Flavobacteriia	976|Bacteroidetes	E	belongs to the imidazoleglycerol-phosphate dehydratase family	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_like,IGPD,PNK3P
TLS3_k127_8573201_5	411477.PARMER_03566	6.163e-84	283.0	COG0118@1|root,COG0118@2|Bacteria,4NF4J@976|Bacteroidetes,2FPAY@200643|Bacteroidia,22XFN@171551|Porphyromonadaceae	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
TLS3_k127_8573201_4	1267211.KI669560_gene2016	9.541e-90	301.0	COG0106@1|root,COG0106@2|Bacteria,4NEEX@976|Bacteroidetes,1IW2E@117747|Sphingobacteriia	976|Bacteroidetes	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
TLS3_k127_8573201_2	1237149.C900_03321	5.246e-119	386.0	COG0107@1|root,COG0107@2|Bacteria,4NE16@976|Bacteroidetes,47K9T@768503|Cytophagia	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
TLS3_k127_8573201_6	926556.Echvi_2517	6.186e-80	272.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,4NERE@976|Bacteroidetes,47KYT@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the PRA-CH family	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
TLS3_k127_8573201_0	1237149.C900_03312	1.75e-254	791.0	COG1249@1|root,COG1249@2|Bacteria,4NJ2P@976|Bacteroidetes,47NRN@768503|Cytophagia	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_8573201_7	1237149.C900_03356	0.0005907	48.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HATPase_c,HisKA,PAS_9,Response_reg
TLS3_k127_8576614_2	1239962.C943_00989	4.479e-14	74.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	MA20_20735	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_8576614_3	1239962.C943_00133	2.452e-08	60.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	MA20_20735	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_8576614_0	1358423.N180_17505	7.969e-195	619.0	COG0308@1|root,COG0308@2|Bacteria,4NFNJ@976|Bacteroidetes,1IR1K@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
TLS3_k127_8577484_1	1185876.BN8_06002	1.709e-75	259.0	COG1172@1|root,COG1172@2|Bacteria,4NHD9@976|Bacteroidetes,47KFH@768503|Cytophagia	976|Bacteroidetes	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10439,ko:K10440	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
TLS3_k127_8577484_0	1185876.BN8_05996	1.238e-166	535.0	COG1129@1|root,COG1129@2|Bacteria,4PKJP@976|Bacteroidetes,47JPJ@768503|Cytophagia	976|Bacteroidetes	G	ABC transporter	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
TLS3_k127_8586916_0	1237149.C900_00814	1.076e-146	468.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,47KYI@768503|Cytophagia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
TLS3_k127_8586916_1	1168034.FH5T_10275	1.639e-68	244.0	COG1672@1|root,COG1672@2|Bacteria,4NGM3@976|Bacteroidetes,2FM92@200643|Bacteroidia	976|Bacteroidetes	S	ATPase (AAA superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_2
TLS3_k127_8589500_5	1170562.Cal6303_4120	0.0009594	44.0	COG0457@1|root,COG0457@2|Bacteria,1GE9K@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
TLS3_k127_8589500_0	153721.MYP_1593	8.208e-183	581.0	COG0465@1|root,COG0465@2|Bacteria,4PKMT@976|Bacteroidetes,47N5V@768503|Cytophagia	976|Bacteroidetes	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,TPR_19
TLS3_k127_8589500_1	1121859.KB890750_gene337	5.621e-117	382.0	COG2321@1|root,COG2321@2|Bacteria,4NDTZ@976|Bacteroidetes,47KPT@768503|Cytophagia	976|Bacteroidetes	S	Putative neutral zinc metallopeptidase	ypfJ	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
TLS3_k127_8589500_3	1237149.C900_03977	3.33e-61	215.0	COG0838@1|root,COG0838@2|Bacteria,4NQET@976|Bacteroidetes,47PRF@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
TLS3_k127_8589500_2	1237149.C900_03978	2.758e-102	333.0	COG0377@1|root,COG0377@2|Bacteria,4NHZ2@976|Bacteroidetes,47J9U@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
TLS3_k127_8589500_4	1237149.C900_03981	2.85e-24	105.0	COG0852@1|root,COG0852@2|Bacteria,4NPGA@976|Bacteroidetes,47PNZ@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
TLS3_k127_879533_1	1464048.JNZS01000012_gene3323	2.503e-23	118.0	COG3250@1|root,COG3525@1|root,COG3250@2|Bacteria,COG3525@2|Bacteria,2GK90@201174|Actinobacteria,4DC7E@85008|Micromonosporales	201174|Actinobacteria	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b
TLS3_k127_879533_0	376686.Fjoh_1208	1.924e-50	207.0	COG0366@1|root,COG5492@1|root,COG0366@2|Bacteria,COG5492@2|Bacteria,4NT99@976|Bacteroidetes,1I25B@117743|Flavobacteriia,2NUT5@237|Flavobacterium	976|Bacteroidetes	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Big_2,CBM26,DM13,DUF4979
TLS3_k127_880373_5	1250232.JQNJ01000001_gene3351	2.655e-44	167.0	COG4798@1|root,COG4798@2|Bacteria,4NII9@976|Bacteroidetes,1IJX2@117743|Flavobacteriia	976|Bacteroidetes	S	Fibrillarin	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_25,Methyltransf_31
TLS3_k127_880373_0	1237149.C900_04554	0.0	1283.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,47JE2@768503|Cytophagia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
TLS3_k127_880373_1	468059.AUHA01000003_gene2012	1.462e-166	532.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1IR44@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
TLS3_k127_880373_2	1237149.C900_04556	8.253e-163	518.0	COG1398@1|root,COG1398@2|Bacteria,4NJI9@976|Bacteroidetes,47XKP@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_880373_4	1237149.C900_01856	1.835e-63	224.0	COG1595@1|root,COG1595@2|Bacteria,4P4V9@976|Bacteroidetes,47XV7@768503|Cytophagia	976|Bacteroidetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_880373_3	1124780.ANNU01000025_gene3374	1.575e-133	428.0	COG1398@1|root,COG1398@2|Bacteria,4NE0I@976|Bacteroidetes,47KJ0@768503|Cytophagia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_906803_3	1185876.BN8_03976	7.055e-43	160.0	COG1082@1|root,COG1082@2|Bacteria,4NIDT@976|Bacteroidetes,47JR4@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_906803_0	926549.KI421517_gene1643	0.0	1115.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NEZ5@976|Bacteroidetes,47JIJ@768503|Cytophagia	976|Bacteroidetes	C	Membrane-bound dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
TLS3_k127_906803_1	760192.Halhy_0742	1.638e-274	847.0	COG0673@1|root,COG0673@2|Bacteria,4NDYI@976|Bacteroidetes,1IP4M@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
TLS3_k127_906803_2	760192.Halhy_3739	2.262e-176	560.0	COG2271@1|root,COG2271@2|Bacteria,4PM8E@976|Bacteroidetes,1J0WC@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Major facilitator superfamily MFS-1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_910791_0	1237149.C900_05108	5.197e-312	985.0	COG1413@1|root,COG1413@2|Bacteria,4PKPI@976|Bacteroidetes,47NQS@768503|Cytophagia	976|Bacteroidetes	C	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,cNMP_binding
TLS3_k127_910791_3	1237149.C900_05109	7.719e-51	187.0	COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes,47MRT@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane chaperone Skp (OmpH)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TLS3_k127_910791_1	1237149.C900_05111	1.923e-69	240.0	28Q4Y@1|root,2ZCN1@2|Bacteria,4NRPX@976|Bacteroidetes,47P9K@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_910791_2	1237149.C900_05115	1.937e-61	213.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,47PIB@768503|Cytophagia	976|Bacteroidetes	S	carbonic anhydrase acetyltransferase	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
TLS3_k127_919873_2	1279009.ADICEAN_00198	9.195e-07	60.0	2C9G6@1|root,330W3@2|Bacteria,4NVA7@976|Bacteroidetes,47RZD@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_919873_0	1123277.KB893186_gene5449	6.091e-157	505.0	COG1304@1|root,COG1304@2|Bacteria,4NEBK@976|Bacteroidetes,47P2H@768503|Cytophagia	976|Bacteroidetes	C	FMN-dependent dehydrogenase	lldD	-	1.1.2.3,1.13.12.4	ko:K00101,ko:K00467	ko00620,ko01100,map00620,map01100	-	R00196,R00319	RC00044,RC01312	ko00000,ko00001,ko01000	-	-	-	FMN_dh
TLS3_k127_919873_1	1237149.C900_02624	2.937e-107	352.0	2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,47P85@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
TLS3_k127_928141_8	1434325.AZQN01000002_gene728	1.857e-26	113.0	COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,4NETR@976|Bacteroidetes,47MJC@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DUF2062,Glycos_transf_2
TLS3_k127_928141_1	1197477.IA57_04700	8.911e-98	326.0	COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,4NETR@976|Bacteroidetes,1HY3M@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DUF2062,Glycos_transf_2
TLS3_k127_928141_9	1122605.KB893647_gene262	2.545e-26	112.0	COG0764@1|root,COG0764@2|Bacteria,4NSGQ@976|Bacteroidetes,1IUPZ@117747|Sphingobacteriia	976|Bacteroidetes	I	FabA-like domain	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
TLS3_k127_928141_5	1122605.KB893647_gene261	7.472e-35	141.0	29ETG@1|root,301R8@2|Bacteria,4NSXB@976|Bacteroidetes,1IZER@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_928141_3	485918.Cpin_1869	5.438e-64	226.0	COG2834@1|root,COG2834@2|Bacteria,4NT30@976|Bacteroidetes,1IU2D@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
TLS3_k127_928141_4	485918.Cpin_1868	1.013e-60	218.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1ISZA@117747|Sphingobacteriia	976|Bacteroidetes	G	Polysaccharide deacetylase	pgdA	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	DUF3298,Polysacc_deac_1
TLS3_k127_928141_2	485918.Cpin_1867	9.008e-90	309.0	COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,1ISE9@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
TLS3_k127_928141_0	714943.Mucpa_6801	2.671e-142	462.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,1IRGP@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_928141_6	485918.Cpin_1865	6.955e-29	119.0	COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes,1ITV3@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TLS3_k127_928141_7	485918.Cpin_1864	1.203e-27	115.0	COG0304@1|root,COG0304@2|Bacteria,4NMSI@976|Bacteroidetes,1ITHW@117747|Sphingobacteriia	976|Bacteroidetes	IQ	3-oxoacyl-ACP synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_930944_4	1123248.KB893359_gene2159	7.723e-08	56.0	COG3712@1|root,COG3712@2|Bacteria,4NHEW@976|Bacteroidetes,1IY3W@117747|Sphingobacteriia	976|Bacteroidetes	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
TLS3_k127_930944_0	1267535.KB906767_gene5008	2.766e-205	664.0	COG4447@1|root,COG4447@2|Bacteria,3Y2MX@57723|Acidobacteria,2JMA6@204432|Acidobacteriia	204432|Acidobacteriia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_930944_1	1267535.KB906767_gene5008	4.588e-142	480.0	COG4447@1|root,COG4447@2|Bacteria,3Y2MX@57723|Acidobacteria,2JMA6@204432|Acidobacteriia	204432|Acidobacteriia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_930944_2	555500.I215_08191	8.515e-102	338.0	COG0191@1|root,COG0191@2|Bacteria,4NG0A@976|Bacteroidetes,1HZZY@117743|Flavobacteriia	976|Bacteroidetes	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13,4.1.2.40	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01069,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
TLS3_k127_930944_3	880073.Calab_2833	2.473e-89	302.0	COG0524@1|root,COG0524@2|Bacteria,2NP5C@2323|unclassified Bacteria	2|Bacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.15,2.7.1.45	ko:K00852,ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01051,R01541,R02750	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
TLS3_k127_936971_2	1237149.C900_00713	7.959e-137	437.0	COG4867@1|root,COG4867@2|Bacteria,4NFMA@976|Bacteroidetes,47K13@768503|Cytophagia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
TLS3_k127_936971_0	1237149.C900_00714	3.707e-244	762.0	COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,47JD2@768503|Cytophagia	976|Bacteroidetes	H	magnesium chelatase	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Sigma54_activat
TLS3_k127_936971_3	1237149.C900_00715	9.401e-62	220.0	COG2865@1|root,COG2865@2|Bacteria,4NGPG@976|Bacteroidetes,47N5X@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
TLS3_k127_936971_1	1237149.C900_00716	1.454e-240	748.0	COG1875@1|root,COG1875@2|Bacteria,4NDUI@976|Bacteroidetes,47M94@768503|Cytophagia	976|Bacteroidetes	T	PIN domain	ybeZ_1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
TLS3_k127_947093_2	1122605.KB893644_gene1350	1.65e-89	306.0	COG2972@1|root,COG2972@2|Bacteria,4NHG3@976|Bacteroidetes,1INSV@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
TLS3_k127_947093_1	714943.Mucpa_4311	9.974e-102	336.0	COG3279@1|root,COG3279@2|Bacteria,4NEAH@976|Bacteroidetes,1IQME@117747|Sphingobacteriia	976|Bacteroidetes	K	response regulator, receiver	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_947093_0	1123277.KB893173_gene1814	3.148e-107	360.0	COG1835@1|root,COG1835@2|Bacteria,4NIVR@976|Bacteroidetes,47UHK@768503|Cytophagia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS3_k127_949765_1	1123277.KB893172_gene566	1.589e-106	365.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47M0S@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
TLS3_k127_949765_2	926556.Echvi_2064	6.672e-81	276.0	COG3967@1|root,COG3967@2|Bacteria,4NJDN@976|Bacteroidetes,47XGS@768503|Cytophagia	976|Bacteroidetes	M	KR domain	-	-	-	ko:K14189	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
TLS3_k127_949765_3	926556.Echvi_2063	3.569e-51	187.0	COG0664@1|root,COG0664@2|Bacteria,4NPP2@976|Bacteroidetes,47QXU@768503|Cytophagia	976|Bacteroidetes	T	Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
TLS3_k127_949765_0	1121897.AUGO01000009_gene2852	5.584e-115	380.0	COG5002@1|root,COG5002@2|Bacteria,4NDTV@976|Bacteroidetes,1HZ7P@117743|Flavobacteriia,2NU7S@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	covS	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,HAMP,HATPase_c,HisKA,PAS
TLS3_k127_950464_0	1123277.KB893174_gene5903	1.858e-287	907.0	COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_950464_2	1123277.KB893174_gene5902	1.752e-48	176.0	COG1695@1|root,COG1695@2|Bacteria,4P3EW@976|Bacteroidetes,47V29@768503|Cytophagia	976|Bacteroidetes	K	PFAM transcriptional regulator PadR family protein	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_950464_1	1237149.C900_04508	1.194e-55	204.0	COG4585@1|root,COG4585@2|Bacteria,4NG0M@976|Bacteroidetes,47KNF@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	narQ	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,PilJ
TLS3_k127_953245_0	929703.KE386491_gene216	0.0	1191.0	COG4206@1|root,COG4206@2|Bacteria,4NFRU@976|Bacteroidetes,47KQA@768503|Cytophagia	976|Bacteroidetes	H	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_953245_1	700598.Niako_7273	8.892e-178	571.0	COG4198@1|root,COG4198@2|Bacteria,4NGWT@976|Bacteroidetes,1IQC2@117747|Sphingobacteriia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
TLS3_k127_964637_0	153721.MYP_3684	2.305e-128	432.0	COG0249@1|root,COG0249@2|Bacteria,4NE6X@976|Bacteroidetes,47KGC@768503|Cytophagia	976|Bacteroidetes	L	PFAM DNA mismatch repair protein MutS	mutS_2	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
TLS3_k127_964637_1	1124780.ANNU01000005_gene2447	2.4e-70	241.0	COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,47PCM@768503|Cytophagia	976|Bacteroidetes	T	GAF domain-containing protein	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
TLS3_k127_964637_2	1499967.BAYZ01000118_gene3252	1.507e-52	187.0	COG0662@1|root,COG0662@2|Bacteria,2NRIV@2323|unclassified Bacteria	2|Bacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_964637_4	1173026.Glo7428_3376	1.754e-10	65.0	COG0504@1|root,COG0504@2|Bacteria,1G0ET@1117|Cyanobacteria	1117|Cyanobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	-	-	-	-	-	-	-	-	-	-	-	-	GATase
TLS3_k127_964637_3	1500281.JQKZ01000018_gene255	1.154e-43	164.0	COG0504@1|root,COG0504@2|Bacteria,4PH1C@976|Bacteroidetes,1IMA9@117743|Flavobacteriia,3ZR4F@59732|Chryseobacterium	976|Bacteroidetes	F	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
TLS3_k127_964637_5	1461577.CCMH01000014_gene608	1.288e-05	48.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,1HX8D@117743|Flavobacteriia	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
TLS3_k127_968646_0	1237149.C900_03347	2.647e-140	450.0	COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,47JHP@768503|Cytophagia	976|Bacteroidetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
TLS3_k127_99541_0	269798.CHU_1208	5.263e-263	843.0	COG0823@1|root,COG3227@1|root,COG0823@2|Bacteria,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,47MX4@768503|Cytophagia	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	npr	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,MAM,PepSY,Peptidase_M4,Peptidase_M4_C,fn3
TLS3_k127_99541_1	504472.Slin_3382	5.279e-101	332.0	COG0702@1|root,COG0702@2|Bacteria,4NGMR@976|Bacteroidetes,47NYS@768503|Cytophagia	976|Bacteroidetes	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS3_k127_99541_3	1279009.ADICEAN_01397	4.093e-43	161.0	2EJE7@1|root,33D57@2|Bacteria,4NXKM@976|Bacteroidetes,47SY9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_99541_4	1121904.ARBP01000002_gene7016	6.882e-38	153.0	COG0589@1|root,COG0589@2|Bacteria,4NHXF@976|Bacteroidetes,47XGN@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_99541_2	1185876.BN8_05055	6.096e-98	329.0	COG3705@1|root,COG3705@2|Bacteria,4NPDC@976|Bacteroidetes,47QQG@768503|Cytophagia	976|Bacteroidetes	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	-	-	-	-	-	-	-	-	-	-	-	-	-
## 4624 queries scanned
## Total time (seconds): 23.44265913963318
## Rate: 197.25 q/s