## Thu Oct 17 15:25:49 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/TLS3_bin.43.fa -m mmseqs --itype genome -o TLS3_bin.43 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/TLS3_bin.43 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
TLS3_k127_1019920_3	755732.Fluta_2062	4.626e-176	555.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,1I19J@117743|Flavobacteriia,2PAIR@246874|Cryomorphaceae	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_1019920_8	485918.Cpin_4761	1.325e-100	330.0	COG0110@1|root,COG0110@2|Bacteria,4NENC@976|Bacteroidetes,1INZ0@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Bacterial transferase hexapeptide (three repeats)	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
TLS3_k127_1019920_2	755732.Fluta_2060	3.764e-190	596.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1HWT7@117743|Flavobacteriia,2PAAK@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
TLS3_k127_1019920_1	755732.Fluta_2059	7.383e-216	676.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,1HWQV@117743|Flavobacteriia,2PA9Z@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM UDP-glucose GDP-mannose dehydrogenase family, NAD binding domain	tuaD	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TLS3_k127_1019920_5	485918.Cpin_1514	8.987e-160	511.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,1IQH3@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_1019920_10	1347342.BN863_35130	1.834e-22	99.0	COG3205@1|root,COG3205@2|Bacteria,4NV6E@976|Bacteroidetes,1I208@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2061
TLS3_k127_1019920_9	1137281.D778_01852	5.454e-78	265.0	COG0529@1|root,COG0529@2|Bacteria,4NGCU@976|Bacteroidetes,1I20M@117743|Flavobacteriia	976|Bacteroidetes	P	Catalyzes the synthesis of activated sulfate	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
TLS3_k127_1019920_4	946077.W5A_00710	5.254e-172	542.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,1HXPZ@117743|Flavobacteriia	976|Bacteroidetes	EH	sulfate adenylyltransferase	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
TLS3_k127_1019920_0	1286632.P278_15270	9.742e-227	707.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,1HXRK@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
TLS3_k127_1019920_6	1286632.P278_15260	5.727e-113	370.0	COG1218@1|root,COG1218@2|Bacteria,4NFHY@976|Bacteroidetes,1HXAV@117743|Flavobacteriia	976|Bacteroidetes	P	COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
TLS3_k127_1019920_7	755732.Fluta_2041	2.579e-102	338.0	2EA9Q@1|root,334E4@2|Bacteria,4NX5I@976|Bacteroidetes,1IASC@117743|Flavobacteriia,2PB5U@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1035743_2	446470.Snas_0537	2.715e-41	176.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1,Kelch_3,Kelch_6
TLS3_k127_1035743_1	984262.SGRA_3159	3.419e-75	285.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NGRJ@976|Bacteroidetes	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,PKD,Peptidase_M43,fn3
TLS3_k127_1035743_3	1313421.JHBV01000041_gene3505	1.436e-09	72.0	COG3291@1|root,COG3291@2|Bacteria,4NG09@976|Bacteroidetes,1J102@117747|Sphingobacteriia	976|Bacteroidetes	S	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
TLS3_k127_1035743_4	1124780.ANNU01000066_gene365	2.704e-07	64.0	COG1520@1|root,COG3209@1|root,COG3291@1|root,COG4733@1|root,COG4932@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,4NDZC@976|Bacteroidetes,47MNQ@768503|Cytophagia	976|Bacteroidetes	O	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,HYR,PKD,SASA,SprB
TLS3_k127_1035743_0	1408433.JHXV01000006_gene2653	0.0	1645.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1HX3Y@117743|Flavobacteriia,2PACY@246874|Cryomorphaceae	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
TLS3_k127_1035743_5	1353276.JADR01000010_gene1738	8.974e-05	52.0	29R7Z@1|root,30C9B@2|Bacteria,4NNMH@976|Bacteroidetes,1I2CI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4412
TLS3_k127_1044405_0	755732.Fluta_3497	6.103e-132	425.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia,2PAJ0@246874|Cryomorphaceae	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
TLS3_k127_1044405_1	755732.Fluta_2064	2.591e-97	335.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_1093641_3	755732.Fluta_0510	1.832e-23	100.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_1093641_0	755732.Fluta_0747	0.0	1116.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,1HXQQ@117743|Flavobacteriia,2PA6G@246874|Cryomorphaceae	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
TLS3_k127_1093641_1	760192.Halhy_5046	4.485e-150	485.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,1IR3F@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_1093641_2	504487.JCM19302_3193	2.268e-47	180.0	COG3103@1|root,COG3103@2|Bacteria,4NU2A@976|Bacteroidetes,1I4GG@117743|Flavobacteriia	976|Bacteroidetes	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
TLS3_k127_1112805_3	755732.Fluta_1822	2.464e-174	581.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	PGAP1
TLS3_k127_1112805_6	755732.Fluta_1843	2.856e-45	178.0	COG5295@1|root,COG5295@2|Bacteria,4NR12@976|Bacteroidetes,1IIJ9@117743|Flavobacteriia	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1112805_4	1121897.AUGO01000007_gene387	6.441e-116	378.0	COG2227@1|root,COG2227@2|Bacteria,4NF6D@976|Bacteroidetes,1HXVW@117743|Flavobacteriia,2NTAA@237|Flavobacterium	976|Bacteroidetes	H	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
TLS3_k127_1112805_5	143224.JQMD01000002_gene2502	6.854e-84	284.0	COG2102@1|root,COG2102@2|Bacteria,4NFQ4@976|Bacteroidetes,1HYJK@117743|Flavobacteriia	976|Bacteroidetes	S	atp-binding	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
TLS3_k127_1112805_0	755732.Fluta_1768	0.0	1168.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,1HYDB@117743|Flavobacteriia,2PAJM@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
TLS3_k127_1112805_1	1313421.JHBV01000031_gene1467	2.269e-291	923.0	COG2866@1|root,COG4447@1|root,COG2866@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes	976|Bacteroidetes	DZ	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	MAM,Sortilin-Vps10
TLS3_k127_1112805_8	1341155.FSS13T_25360	8.494e-05	56.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,2NU0I@237|Flavobacterium	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	CUB,MAM,P_proprotein,Reprolysin_4,fn3
TLS3_k127_1112805_2	755732.Fluta_0306	4.372e-211	676.0	COG2304@1|root,COG2304@2|Bacteria,4NG2X@976|Bacteroidetes,1HXQC@117743|Flavobacteriia	976|Bacteroidetes	P	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,VWA
TLS3_k127_1162205_4	755732.Fluta_2288	1.092e-29	136.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1HXXN@117743|Flavobacteriia,2PAKH@246874|Cryomorphaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TLS3_k127_1162205_3	1408433.JHXV01000019_gene1905	3.158e-37	160.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	1.14.17.3	ko:K00504	-	-	-	-	ko00000,ko01000	-	-	-	-
TLS3_k127_1162205_0	1408433.JHXV01000010_gene565	4.316e-79	282.0	COG2208@1|root,COG2208@2|Bacteria,4PPWM@976|Bacteroidetes,1IKWE@117743|Flavobacteriia,2PBIK@246874|Cryomorphaceae	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	srrB	-	-	-	-	-	-	-	-	-	-	-	CBS,HAMP,SpoIIE,dCache_1
TLS3_k127_1162205_2	456442.Mboo_1006	3.673e-46	181.0	COG3503@1|root,arCOG04370@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
TLS3_k127_1162205_1	755732.Fluta_0307	7.13e-47	174.0	COG1595@1|root,COG1595@2|Bacteria,4P6AG@976|Bacteroidetes,1ICQJ@117743|Flavobacteriia,2PBS0@246874|Cryomorphaceae	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_1162205_5	643867.Ftrac_1564	2.371e-29	123.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TLS3_k127_1189648_3	1121104.AQXH01000001_gene2004	9.213e-06	52.0	2EBK0@1|root,335KF@2|Bacteria,4NVS7@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_1189648_0	755732.Fluta_1505	7.685e-216	677.0	COG1875@1|root,COG1875@2|Bacteria,4NDUI@976|Bacteroidetes,1I7D8@117743|Flavobacteriia,2PAKY@246874|Cryomorphaceae	976|Bacteroidetes	T	Large family of predicted nucleotide-binding domains	ybeZ_1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
TLS3_k127_1189648_2	649349.Lbys_0591	2.056e-44	178.0	COG2755@1|root,COG2755@2|Bacteria,4PAZ7@976|Bacteroidetes,47UVP@768503|Cytophagia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_120086_0	755732.Fluta_0044	7.446e-306	949.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1HXSG@117743|Flavobacteriia,2PA5D@246874|Cryomorphaceae	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
TLS3_k127_120086_1	755732.Fluta_0042	7.21e-37	141.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1HXYS@117743|Flavobacteriia,2PA4W@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
TLS3_k127_1216979_2	1239962.C943_00784	6.117e-07	58.0	2C0BR@1|root,32Z3H@2|Bacteria,4NU9A@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
TLS3_k127_1216979_0	1254432.SCE1572_26895	1.139e-123	410.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,42NJI@68525|delta/epsilon subdivisions,2WJI8@28221|Deltaproteobacteria,2YYYZ@29|Myxococcales	28221|Deltaproteobacteria	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
TLS3_k127_1216979_1	1144313.PMI10_01625	1.599e-104	363.0	COG3497@1|root,COG3497@2|Bacteria,4NEKK@976|Bacteroidetes,1HZQA@117743|Flavobacteriia,2NVB5@237|Flavobacterium	976|Bacteroidetes	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
TLS3_k127_1233627_0	755732.Fluta_1040	2.895e-199	629.0	COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,1IJBB@117743|Flavobacteriia,2PAC6@246874|Cryomorphaceae	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
TLS3_k127_1233627_2	755732.Fluta_1042	3.154e-119	384.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,1HXE9@117743|Flavobacteriia,2PA5G@246874|Cryomorphaceae	976|Bacteroidetes	F	Deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
TLS3_k127_1233627_1	1408433.JHXV01000023_gene3307	2.151e-153	489.0	COG0451@1|root,COG0451@2|Bacteria,4NIZG@976|Bacteroidetes,1IMQF@117743|Flavobacteriia,2PBAU@246874|Cryomorphaceae	976|Bacteroidetes	GM	GDP-mannose 4,6 dehydratase	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
TLS3_k127_1233627_4	1178825.ALIH01000019_gene1232	5.524e-39	149.0	2DM52@1|root,32UG7@2|Bacteria,4NSYJ@976|Bacteroidetes,1I4AH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_4
TLS3_k127_1233627_3	1121373.KB903664_gene2542	2.489e-100	362.0	COG1404@1|root,COG1520@1|root,COG3291@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG3291@2|Bacteria,4NF1M@976|Bacteroidetes,47KVM@768503|Cytophagia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_1233627_5	755732.Fluta_3341	1.304e-26	128.0	COG1470@1|root,COG3386@1|root,COG1470@2|Bacteria,COG3386@2|Bacteria,4PM1B@976|Bacteroidetes,1IKE7@117743|Flavobacteriia,2PC6R@246874|Cryomorphaceae	2|Bacteria	G	SPTR Cell surface protein	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	ASH,BNR_2,NPCBM_assoc,PEGA
TLS3_k127_1236316_0	391587.KAOT1_19412	1.546e-143	464.0	COG1032@1|root,COG1032@2|Bacteria,4NM2X@976|Bacteroidetes,1I8A5@117743|Flavobacteriia	976|Bacteroidetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
TLS3_k127_1236316_1	639282.DEFDS_0729	9.545e-07	60.0	COG1409@1|root,COG1409@2|Bacteria,2GG4Q@200930|Deferribacteres	200930|Deferribacteres	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
TLS3_k127_1267952_2	755732.Fluta_2913	1.414e-32	132.0	2BJHF@1|root,32DUB@2|Bacteria,4P9RZ@976|Bacteroidetes,1ICNC@117743|Flavobacteriia,2PB7V@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1267952_3	1408433.JHXV01000005_gene2518	3.889e-32	140.0	2A94Q@1|root,30Y8X@2|Bacteria,4PC05@976|Bacteroidetes,1ICS0@117743|Flavobacteriia,2PBYD@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1267952_0	755732.Fluta_2915	2.506e-83	294.0	COG1520@1|root,COG1520@2|Bacteria,4PBXV@976|Bacteroidetes,1ICQN@117743|Flavobacteriia,2PBSC@246874|Cryomorphaceae	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1267952_1	755732.Fluta_2920	9.286e-68	234.0	COG1778@1|root,COG1778@2|Bacteria,4NMHD@976|Bacteroidetes,1I1FS@117743|Flavobacteriia,2PBVS@246874|Cryomorphaceae	976|Bacteroidetes	C	TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_3
TLS3_k127_1267952_4	926551.KB900714_gene2040	1.465e-07	53.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,1HZIC@117743|Flavobacteriia,1EQRX@1016|Capnocytophaga	976|Bacteroidetes	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
TLS3_k127_1277407_8	755732.Fluta_3229	5.699e-13	74.0	COG3386@1|root,COG3386@2|Bacteria,4PM1B@976|Bacteroidetes,1IN8T@117743|Flavobacteriia,2PBT6@246874|Cryomorphaceae	976|Bacteroidetes	G	SPTR Cell surface protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
TLS3_k127_1277407_3	485917.Phep_2086	2.549e-92	312.0	COG1357@1|root,COG1396@1|root,COG1357@2|Bacteria,COG1396@2|Bacteria,4NRF4@976|Bacteroidetes	976|Bacteroidetes	K	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Pentapeptide,Pentapeptide_4
TLS3_k127_1277407_5	1229487.AMYW01000024_gene378	4.457e-77	260.0	COG0664@1|root,COG0664@2|Bacteria,4NNIX@976|Bacteroidetes,1I247@117743|Flavobacteriia,2NWD9@237|Flavobacterium	976|Bacteroidetes	T	Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
TLS3_k127_1277407_6	1229487.AMYW01000024_gene379	1.219e-76	261.0	COG2318@1|root,COG2318@2|Bacteria,4NP2C@976|Bacteroidetes,1I23S@117743|Flavobacteriia,2NWVS@237|Flavobacterium	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_1277407_9	421072.IO89_01785	0.000458	48.0	COG4099@1|root,COG4099@2|Bacteria,4NIDF@976|Bacteroidetes,1I48B@117743|Flavobacteriia,3HHXP@358033|Chryseobacterium	976|Bacteroidetes	S	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase,Peptidase_S9
TLS3_k127_1277407_1	177437.HRM2_18520	3.319e-163	520.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,42MWV@68525|delta/epsilon subdivisions,2WJJZ@28221|Deltaproteobacteria,2MJKQ@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
TLS3_k127_1277407_4	755732.Fluta_3732	2.254e-81	274.0	COG2207@1|root,COG2207@2|Bacteria,4PJ0D@976|Bacteroidetes,1IG6G@117743|Flavobacteriia,2PBPB@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_1277407_0	755732.Fluta_3731	0.0	1212.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia,2PAFY@246874|Cryomorphaceae	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
TLS3_k127_1277407_2	755732.Fluta_3729	1.955e-113	374.0	COG0845@1|root,COG2608@1|root,COG0845@2|Bacteria,COG2608@2|Bacteria,4NG8S@976|Bacteroidetes,1HYRA@117743|Flavobacteriia,2PC24@246874|Cryomorphaceae	976|Bacteroidetes	M	Protein of unknown function (DUF3347)	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347
TLS3_k127_1277407_7	1144313.PMI10_00472	1.401e-25	107.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HWXY@117743|Flavobacteriia,2NT1D@237|Flavobacterium	976|Bacteroidetes	Q	Multicopper oxidase	copA	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
TLS3_k127_1299793_7	391598.FBBAL38_01495	3.281e-10	73.0	COG1345@1|root,COG1361@1|root,COG3291@1|root,COG4733@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4NGSK@976|Bacteroidetes,1HXWK@117743|Flavobacteriia	976|Bacteroidetes	N	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	LTD
TLS3_k127_1299793_2	755732.Fluta_3341	2.012e-73	271.0	COG1470@1|root,COG3386@1|root,COG1470@2|Bacteria,COG3386@2|Bacteria,4PM1B@976|Bacteroidetes,1IKE7@117743|Flavobacteriia,2PC6R@246874|Cryomorphaceae	2|Bacteria	G	SPTR Cell surface protein	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	ASH,BNR_2,NPCBM_assoc,PEGA
TLS3_k127_1299793_4	760192.Halhy_3096	4.608e-64	243.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1IZUU@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
TLS3_k127_1299793_0	926562.Oweho_0839	1.203e-143	476.0	COG2849@1|root,COG2849@2|Bacteria,4NW92@976|Bacteroidetes,1IKDQ@117743|Flavobacteriia,2PAPB@246874|Cryomorphaceae	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1299793_3	592029.DDD_0949	3.163e-64	229.0	COG1917@1|root,COG1917@2|Bacteria,4NPHM@976|Bacteroidetes,1IB3T@117743|Flavobacteriia	976|Bacteroidetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1299793_5	755732.Fluta_1630	1.094e-17	98.0	COG3210@1|root,COG5184@1|root,COG3210@2|Bacteria,COG5184@2|Bacteria,4NIDX@976|Bacteroidetes,1I0AY@117743|Flavobacteriia,2PBAP@246874|Cryomorphaceae	976|Bacteroidetes	U	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_1299793_1	313606.M23134_06175	4.88e-101	361.0	COG3386@1|root,COG4932@1|root,COG3386@2|Bacteria,COG4932@2|Bacteria,4NN56@976|Bacteroidetes,47Q8D@768503|Cytophagia	976|Bacteroidetes	M	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS
TLS3_k127_1306737_12	643473.KB235930_gene2252	1.132e-46	180.0	COG0517@1|root,COG3920@1|root,COG0517@2|Bacteria,COG3920@2|Bacteria,1GQI0@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	HATPase_c,HisKA_2,PAS_4
TLS3_k127_1306737_0	755732.Fluta_3296	2.12e-310	970.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1HX4I@117743|Flavobacteriia,2PAEW@246874|Cryomorphaceae	976|Bacteroidetes	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
TLS3_k127_1306737_11	760192.Halhy_5228	2.129e-49	184.0	COG0132@1|root,COG0132@2|Bacteria,4NGKI@976|Bacteroidetes,1IS5T@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
TLS3_k127_1306737_5	755732.Fluta_3298	2.18e-170	546.0	COG0161@1|root,COG0161@2|Bacteria,4NEJN@976|Bacteroidetes,1HX8M@117743|Flavobacteriia,2PAE5@246874|Cryomorphaceae	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,BATS,Radical_SAM
TLS3_k127_1306737_17	755732.Fluta_2775	0.000776	48.0	28HNS@1|root,2Z7WY@2|Bacteria,4NDYC@976|Bacteroidetes,1HYVW@117743|Flavobacteriia,2PAV3@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4856)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4856
TLS3_k127_1306737_3	1123499.KB908028_gene88	7.64e-179	569.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria	1224|Proteobacteria	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
TLS3_k127_1306737_16	755732.Fluta_3307	4.926e-25	110.0	2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,1I5A4@117743|Flavobacteriia,2PB9P@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1306737_13	755732.Fluta_3309	5.436e-42	160.0	COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,1I18Y@117743|Flavobacteriia,2PAYU@246874|Cryomorphaceae	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_1306737_4	755732.Fluta_3310	2.097e-172	544.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,1HWWI@117743|Flavobacteriia,2PACZ@246874|Cryomorphaceae	976|Bacteroidetes	G	Transketolase, pyrimidine binding domain	dxs	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
TLS3_k127_1306737_2	755732.Fluta_3311	1.687e-183	583.0	COG2304@1|root,COG2304@2|Bacteria,4NJF1@976|Bacteroidetes,1I5HE@117743|Flavobacteriia,2PAI7@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
TLS3_k127_1306737_7	755732.Fluta_3312	2.869e-145	470.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,1HWZM@117743|Flavobacteriia,2PA6P@246874|Cryomorphaceae	976|Bacteroidetes	G	PFAM Transketolase, thiamine diphosphate binding domain	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
TLS3_k127_1306737_1	755732.Fluta_3314	5.497e-300	948.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF11,fn3
TLS3_k127_1306737_8	755732.Fluta_3315	2.298e-136	441.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1HXVU@117743|Flavobacteriia,2PA4K@246874|Cryomorphaceae	976|Bacteroidetes	C	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
TLS3_k127_1306737_15	1249997.JHZW01000003_gene3834	5.331e-32	141.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY1Z@117743|Flavobacteriia,2PHYJ@252356|Maribacter	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
TLS3_k127_1306737_14	755732.Fluta_3316	4.514e-41	168.0	COG3087@1|root,COG3087@2|Bacteria,4PHIW@976|Bacteroidetes,1ICR6@117743|Flavobacteriia,2PBV4@246874|Cryomorphaceae	976|Bacteroidetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
TLS3_k127_1306737_6	755732.Fluta_3317	6.777e-146	466.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,1HX48@117743|Flavobacteriia,2PA6T@246874|Cryomorphaceae	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_1306737_10	1250005.PHEL85_2756	9.422e-57	208.0	COG0697@1|root,COG0697@2|Bacteria,4NGWA@976|Bacteroidetes,1HWX9@117743|Flavobacteriia,3VV7J@52959|Polaribacter	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_1306737_9	926562.Oweho_0936	1.632e-110	367.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,1HX8D@117743|Flavobacteriia,2PA88@246874|Cryomorphaceae	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
TLS3_k127_1318297_3	1249997.JHZW01000003_gene2177	5.309e-17	83.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1HX11@117743|Flavobacteriia,2PGQT@252356|Maribacter	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	fjo14	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
TLS3_k127_1318297_1	746697.Aeqsu_0814	2.632e-38	154.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1HXXH@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
TLS3_k127_1318297_0	1094466.KQS_12615	1.526e-171	557.0	COG5295@1|root,COG5295@2|Bacteria,4NV9S@976|Bacteroidetes,1I8F6@117743|Flavobacteriia,2P0DN@237|Flavobacterium	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
TLS3_k127_1318297_2	313595.P700755_003990	2.908e-22	100.0	2E78C@1|root,331S1@2|Bacteria,4NPWT@976|Bacteroidetes,1I2MW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_132218_0	641526.ADIWIN_1299	1.2e-293	924.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1HWUW@117743|Flavobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
TLS3_k127_132218_1	755732.Fluta_2672	9.985e-292	914.0	COG4206@1|root,COG4206@2|Bacteria,4PKY5@976|Bacteroidetes,1IJH2@117743|Flavobacteriia	976|Bacteroidetes	H	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
TLS3_k127_1326659_1	1218108.KB908291_gene469	7.96e-58	208.0	COG2949@1|root,COG2949@2|Bacteria,4NNQS@976|Bacteroidetes,1I1DV@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	sanA	-	-	ko:K03748	-	-	-	-	ko00000	-	-	-	DUF218
TLS3_k127_1326659_0	755732.Fluta_0012	4.865e-181	579.0	COG5316@1|root,COG5316@2|Bacteria,4NGER@976|Bacteroidetes,1HYI0@117743|Flavobacteriia,2PBG5@246874|Cryomorphaceae	976|Bacteroidetes	S	N-terminal domain of unknown function (DUF4140)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140,Plug
TLS3_k127_1333925_11	643867.Ftrac_0042	7.378e-48	178.0	COG1704@1|root,COG1704@2|Bacteria,4NMP9@976|Bacteroidetes,47RCD@768503|Cytophagia	976|Bacteroidetes	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
TLS3_k127_1333925_9	686340.Metal_2800	3.253e-73	258.0	COG0457@1|root,COG0457@2|Bacteria,1N9AG@1224|Proteobacteria,1SD5U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3137)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3137
TLS3_k127_1333925_5	1122226.AUHX01000006_gene2231	5.104e-160	514.0	COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,1HWNW@117743|Flavobacteriia	976|Bacteroidetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS3_k127_1333925_0	755732.Fluta_1299	0.0	1446.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1HXG2@117743|Flavobacteriia,2PAGS@246874|Cryomorphaceae	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase N-terminus	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
TLS3_k127_1333925_17	592029.DDD_0394	6.627e-05	54.0	COG4733@1|root,COG4886@1|root,COG4733@2|Bacteria,COG4886@2|Bacteria,4PHVI@976|Bacteroidetes,1IG6U@117743|Flavobacteriia,3HKW5@363408|Nonlabens	976|Bacteroidetes	C	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1333925_1	755732.Fluta_1514	0.0	1091.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1HXHI@117743|Flavobacteriia,2PA58@246874|Cryomorphaceae	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
TLS3_k127_1333925_4	755732.Fluta_1306	3.07e-181	577.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,1HXRS@117743|Flavobacteriia,2PAHF@246874|Cryomorphaceae	976|Bacteroidetes	E	Saccharopine dehydrogenase C-terminal domain	-	-	1.5.1.10,1.5.1.7	ko:K00290,ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R02315	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
TLS3_k127_1333925_8	1237149.C900_03315	1.862e-113	369.0	COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,47JWX@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
TLS3_k127_1333925_3	755732.Fluta_1165	2.684e-264	840.0	COG0457@1|root,COG0457@2|Bacteria,4NDV9@976|Bacteroidetes,1HXND@117743|Flavobacteriia,2PAMZ@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeats	sprE	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
TLS3_k127_1333925_13	385682.AFSL01000008_gene2603	1.985e-25	110.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,2FUPU@200643|Bacteroidia,3XK7D@558415|Marinilabiliaceae	976|Bacteroidetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
TLS3_k127_1333925_15	1443665.JACA01000012_gene1326	1.733e-14	78.0	2ECZA@1|root,336WB@2|Bacteria,4NWPW@976|Bacteroidetes,1I5GC@117743|Flavobacteriia,2YK4C@290174|Aquimarina	976|Bacteroidetes	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
TLS3_k127_1333925_16	616991.JPOO01000003_gene2568	1.879e-13	75.0	2BY49@1|root,32U9Y@2|Bacteria,4NSER@976|Bacteroidetes,1I4B5@117743|Flavobacteriia,23HIS@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1333925_6	1121887.AUDK01000003_gene2591	2.105e-124	409.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1HX71@117743|Flavobacteriia,2NSAS@237|Flavobacterium	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
TLS3_k127_1333925_14	1144313.PMI10_02597	3.616e-22	97.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,1I53G@117743|Flavobacteriia,2NXFM@237|Flavobacterium	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
TLS3_k127_1333925_12	746697.Aeqsu_1175	6.254e-44	165.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1I239@117743|Flavobacteriia	976|Bacteroidetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
TLS3_k127_1333925_10	755732.Fluta_1159	7.896e-56	200.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,1I28E@117743|Flavobacteriia,2PB3Q@246874|Cryomorphaceae	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
TLS3_k127_1333925_2	755732.Fluta_1158	7.438e-307	945.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1HXGV@117743|Flavobacteriia,2PABN@246874|Cryomorphaceae	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
TLS3_k127_1333925_7	755732.Fluta_1156	2.589e-117	384.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1HX6V@117743|Flavobacteriia,2PABW@246874|Cryomorphaceae	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
TLS3_k127_1363779_4	755732.Fluta_3326	1.625e-24	103.0	COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,1HX6E@117743|Flavobacteriia,2PAAB@246874|Cryomorphaceae	976|Bacteroidetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
TLS3_k127_1363779_2	1317122.ATO12_01870	3.873e-37	143.0	2E4J8@1|root,32ZEA@2|Bacteria,4NW6Q@976|Bacteroidetes,1I69T@117743|Flavobacteriia,2YJEK@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2541
TLS3_k127_1363779_0	755732.Fluta_3601	1.617e-305	951.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,1HYA6@117743|Flavobacteriia,2PA9S@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family M49	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M49
TLS3_k127_1363779_1	755732.Fluta_1330	5.026e-137	439.0	COG2820@1|root,COG2820@2|Bacteria,4NESQ@976|Bacteroidetes,1I8FV@117743|Flavobacteriia,2PBBS@246874|Cryomorphaceae	976|Bacteroidetes	F	Phosphorylase superfamily	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
TLS3_k127_1363779_3	880070.Cycma_5098	9.634e-29	122.0	2E9TR@1|root,333ZQ@2|Bacteria,4NVUY@976|Bacteroidetes	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
TLS3_k127_1363779_5	109478.XP_005859314.1	7.709e-11	66.0	COG0666@1|root,COG4886@1|root,KOG0619@2759|Eukaryota,KOG4177@2759|Eukaryota,39R13@33154|Opisthokonta,3BEUG@33208|Metazoa,3CUKB@33213|Bilateria,480NC@7711|Chordata,4939C@7742|Vertebrata,3J38F@40674|Mammalia,4M0F8@9397|Chiroptera	33208|Metazoa	T	P53-induced protein with a death domain	PIDD1	GO:0000075,GO:0000077,GO:0000278,GO:0003674,GO:0005102,GO:0005123,GO:0005126,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005794,GO:0005829,GO:0006355,GO:0006919,GO:0006950,GO:0006974,GO:0006977,GO:0007049,GO:0007093,GO:0007154,GO:0007165,GO:0007346,GO:0008150,GO:0009889,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010604,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010948,GO:0010950,GO:0010952,GO:0012505,GO:0019219,GO:0019222,GO:0022402,GO:0023051,GO:0023052,GO:0023056,GO:0030162,GO:0030330,GO:0031323,GO:0031325,GO:0031326,GO:0031570,GO:0031571,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032813,GO:0033554,GO:0035556,GO:0042770,GO:0042981,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043280,GO:0043281,GO:0044093,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044773,GO:0044774,GO:0044783,GO:0044819,GO:0045786,GO:0045787,GO:0045862,GO:0045930,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051090,GO:0051091,GO:0051092,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051336,GO:0051345,GO:0051716,GO:0051726,GO:0052547,GO:0052548,GO:0060255,GO:0060548,GO:0065007,GO:0065009,GO:0070013,GO:0071156,GO:0071158,GO:0072331,GO:0072395,GO:0072401,GO:0072413,GO:0072422,GO:0072431,GO:0080090,GO:0090068,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902041,GO:1902043,GO:1902400,GO:1902402,GO:1902403,GO:1902806,GO:1902807,GO:1903047,GO:1903506,GO:2000045,GO:2000112,GO:2000116,GO:2000134,GO:2001056,GO:2001141,GO:2001233,GO:2001235,GO:2001236,GO:2001238	-	ko:K10130	ko04064,ko04115,ko04210,map04064,map04115,map04210	-	-	-	ko00000,ko00001	-	-	-	Death,LRR_8,Peptidase_S68,ZU5
TLS3_k127_1366257_1	1296416.JACB01000070_gene62	2.142e-66	233.0	COG2972@1|root,COG2972@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia,2YKPU@290174|Aquimarina	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Y_Y_Y
TLS3_k127_1366257_0	1296416.JACB01000070_gene63	1.595e-66	234.0	COG3279@1|root,COG3279@2|Bacteria,4NZW0@976|Bacteroidetes,1I7C2@117743|Flavobacteriia,2YKFX@290174|Aquimarina	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_1366257_2	1107311.Q767_01615	1.354e-59	217.0	COG1520@1|root,COG3291@1|root,COG3386@1|root,COG5306@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5306@2|Bacteria,4NNUN@976|Bacteroidetes,1IKME@117743|Flavobacteriia,2NXAD@237|Flavobacterium	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,SBBP
TLS3_k127_1366257_3	1123508.JH636439_gene1132	1.099e-27	120.0	COG1520@1|root,COG2373@1|root,COG2931@1|root,COG3386@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2J4W7@203682|Planctomycetes	2|Bacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,CHU_C,DUF11,DUF4347,SdrD_B
TLS3_k127_1374591_5	755732.Fluta_1576	3.058e-58	210.0	COG1981@1|root,COG1981@2|Bacteria,4NEWG@976|Bacteroidetes,1HX86@117743|Flavobacteriia,2PB17@246874|Cryomorphaceae	976|Bacteroidetes	S	Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
TLS3_k127_1374591_3	755732.Fluta_1578	3.751e-116	379.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,1HWQA@117743|Flavobacteriia,2PAFB@246874|Cryomorphaceae	976|Bacteroidetes	I	Enoyl-CoA hydratase/isomerase	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
TLS3_k127_1374591_0	755732.Fluta_1579	1.072e-173	559.0	COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,1HWQF@117743|Flavobacteriia,2PADY@246874|Cryomorphaceae	976|Bacteroidetes	S	Membrane protein involved in the export of O-antigen and teichoic acid	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
TLS3_k127_1374591_4	1121899.Q764_09965	5.094e-65	226.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,1I1AC@117743|Flavobacteriia,2NVXP@237|Flavobacterium	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
TLS3_k127_1374591_2	983544.Lacal_1077	2.369e-153	492.0	COG1208@1|root,COG1208@2|Bacteria,4NE97@976|Bacteroidetes,1HYFQ@117743|Flavobacteriia	976|Bacteroidetes	JM	dTDP-glucose pyrophosphorylase	rffH	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
TLS3_k127_1374591_1	755732.Fluta_1633	4.193e-159	519.0	COG0457@1|root,COG0457@2|Bacteria,4NDVW@976|Bacteroidetes,1IEQF@117743|Flavobacteriia,2PAWN@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
TLS3_k127_1423975_1	1356852.N008_20925	5.932e-91	301.0	COG1451@1|root,COG1451@2|Bacteria,4NIY4@976|Bacteroidetes,47R1S@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
TLS3_k127_1423975_10	1443665.JACA01000073_gene2046	2.04e-11	67.0	2C2X5@1|root,343UY@2|Bacteria,4P6P3@976|Bacteroidetes,1IHXS@117743|Flavobacteriia,2YK68@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
TLS3_k127_1423975_13	1122225.AULQ01000002_gene628	5.087e-09	64.0	2E9ZF@1|root,3344X@2|Bacteria,4P5G2@976|Bacteroidetes,1IA51@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1423975_9	745718.JADT01000017_gene1122	1.566e-13	81.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
TLS3_k127_1423975_0	1250006.JHZZ01000001_gene1343	8.011e-96	327.0	COG0433@1|root,COG0433@2|Bacteria,4NU1B@976|Bacteroidetes,1ICEF@117743|Flavobacteriia,3VX6N@52959|Polaribacter	976|Bacteroidetes	S	Type IV secretion-system coupling protein DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TraG-D_C,TrwB_AAD_bind
TLS3_k127_1423975_3	869209.Tresu_1693	1.987e-57	203.0	2FE6T@1|root,3466M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1423975_14	1472716.KBK24_0116710	2.309e-05	55.0	28Y4V@1|root,2ZK0A@2|Bacteria,1PINU@1224|Proteobacteria,2W78W@28216|Betaproteobacteria,1KE3J@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1423975_8	1250006.JHZZ01000001_gene1349	2.948e-16	85.0	2F24P@1|root,33V36@2|Bacteria,4P2YI@976|Bacteroidetes,1I8N1@117743|Flavobacteriia,3VX94@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1423975_7	1250005.PHEL85_3421	7.055e-17	88.0	2F9FD@1|root,341S0@2|Bacteria,4P4MV@976|Bacteroidetes,1I9EY@117743|Flavobacteriia,3VXDV@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1423975_4	1250006.JHZZ01000001_gene1344	4.791e-35	139.0	COG2003@1|root,COG2003@2|Bacteria,4P9I8@976|Bacteroidetes,1ICBI@117743|Flavobacteriia,3VXBK@52959|Polaribacter	976|Bacteroidetes	L	RadC-like JAB domain	-	-	-	-	-	-	-	-	-	-	-	-	RadC
TLS3_k127_1423975_2	1250006.JHZZ01000001_gene1345	8.962e-77	265.0	COG0338@1|root,COG0338@2|Bacteria,4NNKG@976|Bacteroidetes,1I2BU@117743|Flavobacteriia,3VWYZ@52959|Polaribacter	976|Bacteroidetes	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
TLS3_k127_1423975_6	1341155.FSS13T_12140	3.312e-28	130.0	COG2247@1|root,COG3391@1|root,COG2247@2|Bacteria,COG3391@2|Bacteria,4NPTS@976|Bacteroidetes,1I3F0@117743|Flavobacteriia	976|Bacteroidetes	M	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
TLS3_k127_1423975_15	1121129.KB903367_gene2759	0.0003525	44.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,2FNCU@200643|Bacteroidia,22X60@171551|Porphyromonadaceae	976|Bacteroidetes	KMT	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,TonB_C
TLS3_k127_1424535_1	1408433.JHXV01000005_gene2462	2.966e-41	154.0	2E5WH@1|root,30K07@2|Bacteria,4P5HE@976|Bacteroidetes,1ICRB@117743|Flavobacteriia,2PBVH@246874|Cryomorphaceae	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
TLS3_k127_1424535_3	1087481.AGFX01000016_gene2872	0.0007427	42.0	2AWWR@1|root,31NU9@2|Bacteria,1TZQA@1239|Firmicutes,4I8ZQ@91061|Bacilli,270SK@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1424535_0	755732.Fluta_0831	5.57e-200	629.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1HX43@117743|Flavobacteriia,2PAD1@246874|Cryomorphaceae	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
TLS3_k127_143430_2	755732.Fluta_2719	4.062e-146	465.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,1HXV7@117743|Flavobacteriia,2PAJB@246874|Cryomorphaceae	976|Bacteroidetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_143430_0	755732.Fluta_2713	1.031e-221	697.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1HX2V@117743|Flavobacteriia,2PAIA@246874|Cryomorphaceae	976|Bacteroidetes	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
TLS3_k127_143430_1	755732.Fluta_2712	2.646e-205	649.0	COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,1HX0E@117743|Flavobacteriia,2PAIB@246874|Cryomorphaceae	976|Bacteroidetes	J	tRNA synthetase class II core domain (G, H, P, S and T)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
TLS3_k127_143430_3	391587.KAOT1_21522	3.981e-53	195.0	2CG2N@1|root,33J74@2|Bacteria,4NZ62@976|Bacteroidetes,1I6ZJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1453145_16	755732.Fluta_0777	3.068e-32	126.0	COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,1I45R@117743|Flavobacteriia,2PB3V@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
TLS3_k127_1453145_0	755732.Fluta_0776	1.338e-154	490.0	COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes,1HXDV@117743|Flavobacteriia,2PAH2@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
TLS3_k127_1453145_11	755732.Fluta_0775	2.991e-47	170.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,1I2W9@117743|Flavobacteriia,2PAXZ@246874|Cryomorphaceae	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
TLS3_k127_1453145_10	755732.Fluta_0774	4.068e-60	210.0	COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,1I18F@117743|Flavobacteriia,2PAWX@246874|Cryomorphaceae	976|Bacteroidetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
TLS3_k127_1453145_2	755732.Fluta_0773	1.163e-130	419.0	COG0092@1|root,COG0092@2|Bacteria,4NE9F@976|Bacteroidetes,1HXI0@117743|Flavobacteriia,2PAJY@246874|Cryomorphaceae	976|Bacteroidetes	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
TLS3_k127_1453145_6	755732.Fluta_0772	4.232e-76	256.0	COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,1I16U@117743|Flavobacteriia,2PAQD@246874|Cryomorphaceae	976|Bacteroidetes	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
TLS3_k127_1453145_18	755732.Fluta_0771	1.878e-16	80.0	COG0255@1|root,COG0255@2|Bacteria,4NUSC@976|Bacteroidetes,1I53X@117743|Flavobacteriia,2PB8X@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
TLS3_k127_1453145_14	755732.Fluta_0770	2.629e-40	150.0	COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,1I2TE@117743|Flavobacteriia,2PAYV@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
TLS3_k127_1453145_8	755732.Fluta_0769	1.601e-61	213.0	COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,1I22S@117743|Flavobacteriia,2PATX@246874|Cryomorphaceae	976|Bacteroidetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
TLS3_k127_1453145_12	755732.Fluta_0768	1.125e-41	155.0	COG0198@1|root,COG0198@2|Bacteria,4NSTI@976|Bacteroidetes,1I2VR@117743|Flavobacteriia,2PB5H@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
TLS3_k127_1453145_3	755732.Fluta_0767	2.08e-95	314.0	COG0094@1|root,COG0094@2|Bacteria,4NEGY@976|Bacteroidetes,1HX1E@117743|Flavobacteriia,2PAN9@246874|Cryomorphaceae	976|Bacteroidetes	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
TLS3_k127_1453145_15	755732.Fluta_0766	1.441e-37	144.0	COG0199@1|root,COG0199@2|Bacteria,4NQ6N@976|Bacteroidetes,1I2TX@117743|Flavobacteriia,2PB2N@246874|Cryomorphaceae	976|Bacteroidetes	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
TLS3_k127_1453145_9	755732.Fluta_0765	3.773e-60	211.0	COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes,1I20H@117743|Flavobacteriia,2PAXW@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
TLS3_k127_1453145_4	755732.Fluta_0764	3.835e-89	296.0	COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,1HWK7@117743|Flavobacteriia,2PART@246874|Cryomorphaceae	976|Bacteroidetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
TLS3_k127_1453145_13	1406840.Q763_00450	1.638e-41	155.0	COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,1I2S3@117743|Flavobacteriia,2NW83@237|Flavobacterium	976|Bacteroidetes	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
TLS3_k127_1453145_5	755732.Fluta_0762	2.464e-86	287.0	COG0098@1|root,COG0098@2|Bacteria,4NG1Z@976|Bacteroidetes,1HXH9@117743|Flavobacteriia,2PARE@246874|Cryomorphaceae	976|Bacteroidetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
TLS3_k127_1453145_17	755732.Fluta_0761	1.21e-17	83.0	COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,1I55H@117743|Flavobacteriia,2PB6D@246874|Cryomorphaceae	976|Bacteroidetes	J	TIGRFAM ribosomal protein L30, bacterial organelle	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
TLS3_k127_1453145_7	755732.Fluta_0760	2.58e-66	229.0	COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,1I17M@117743|Flavobacteriia,2PAU9@246874|Cryomorphaceae	976|Bacteroidetes	J	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
TLS3_k127_1453145_1	755732.Fluta_0759	4.329e-152	487.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,1HWR7@117743|Flavobacteriia,2PA4H@246874|Cryomorphaceae	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
TLS3_k127_1462804_1	1305737.JAFX01000001_gene2606	1.172e-23	115.0	COG3422@1|root,COG3422@2|Bacteria,4NHE4@976|Bacteroidetes,47NKA@768503|Cytophagia	976|Bacteroidetes	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1462804_2	1173023.KE650771_gene5293	2.265e-16	93.0	COG0729@1|root,COG0729@2|Bacteria,1GDRV@1117|Cyanobacteria	1117|Cyanobacteria	M	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1462804_0	177437.HRM2_13110	1.93e-138	477.0	COG3299@1|root,COG3299@2|Bacteria,1MY5J@1224|Proteobacteria,42MH5@68525|delta/epsilon subdivisions,2WM0U@28221|Deltaproteobacteria,2MMR7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
TLS3_k127_1533321_7	1121904.ARBP01000004_gene861	8.876e-29	117.0	COG0438@1|root,COG0438@2|Bacteria,4NEZI@976|Bacteroidetes,47PDJ@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_1533321_5	755732.Fluta_4037	3.553e-45	172.0	298K1@1|root,32FY8@2|Bacteria,4PK0P@976|Bacteroidetes,1ICRH@117743|Flavobacteriia,2PBW9@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1533321_3	755732.Fluta_4038	5.51e-69	242.0	COG2849@1|root,COG2849@2|Bacteria,4NP2Z@976|Bacteroidetes,1I22V@117743|Flavobacteriia,2PB39@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_1533321_4	755732.Fluta_4039	3.819e-54	196.0	COG0241@1|root,COG0241@2|Bacteria,4NR54@976|Bacteroidetes,1IG8I@117743|Flavobacteriia,2PBUW@246874|Cryomorphaceae	976|Bacteroidetes	E	Polynucleotide kinase 3 phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like,PNK3P
TLS3_k127_1533321_2	755732.Fluta_4040	1.851e-162	516.0	COG0463@1|root,COG0463@2|Bacteria,4NEVT@976|Bacteroidetes,1HXT8@117743|Flavobacteriia,2PAI1@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyltransferase like family 2	arnC	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_1533321_1	1408433.JHXV01000005_gene2349	2.137e-224	719.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia,2PBIN@246874|Cryomorphaceae	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
TLS3_k127_1533321_0	755732.Fluta_3330	0.0	1273.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1HYUM@117743|Flavobacteriia,2PA86@246874|Cryomorphaceae	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
TLS3_k127_1533321_6	485918.Cpin_2827	4.988e-37	144.0	COG0526@1|root,COG0526@2|Bacteria,4NM4Y@976|Bacteroidetes,1IT0A@117747|Sphingobacteriia	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
TLS3_k127_1548461_0	1408473.JHXO01000007_gene1002	1.578e-131	428.0	COG3621@1|root,COG3621@2|Bacteria,4NG71@976|Bacteroidetes	976|Bacteroidetes	S	COG3621 Patatin	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
TLS3_k127_1551158_2	1443665.JACA01000001_gene2900	5.814e-27	118.0	2ECA3@1|root,3368F@2|Bacteria,4NW35@976|Bacteroidetes,1IM9X@117743|Flavobacteriia,2YITU@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1551158_1	1270196.JCKI01000008_gene1374	1.279e-35	146.0	COG4585@1|root,COG4585@2|Bacteria,4NN4R@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TLS3_k127_1551158_0	755732.Fluta_1232	5.586e-60	215.0	COG2197@1|root,COG2197@2|Bacteria,4NMTW@976|Bacteroidetes,1I1JF@117743|Flavobacteriia,2PBU0@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_1553275_6	1121344.JHZO01000003_gene1028	7.083e-05	53.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	hetI	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.8.7	ko:K00997,ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
TLS3_k127_1553275_0	755732.Fluta_1422	1.829e-212	674.0	COG3049@1|root,COG3049@2|Bacteria,4PKMY@976|Bacteroidetes,1IKDD@117743|Flavobacteriia,2PAAJ@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
TLS3_k127_1553275_2	755732.Fluta_1423	7.298e-167	534.0	COG1541@1|root,COG1541@2|Bacteria,4NGRR@976|Bacteroidetes,1HZ2J@117743|Flavobacteriia,2PAF6@246874|Cryomorphaceae	976|Bacteroidetes	H	AMP-binding enzyme	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
TLS3_k127_1553275_3	755732.Fluta_1425	4.098e-158	508.0	COG0644@1|root,COG0644@2|Bacteria,4NEI6@976|Bacteroidetes,1HYZB@117743|Flavobacteriia,2PAAS@246874|Cryomorphaceae	976|Bacteroidetes	C	Tryptophan halogenase	fixC	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
TLS3_k127_1553275_1	1434325.AZQN01000002_gene747	1.276e-184	590.0	COG1233@1|root,COG1233@2|Bacteria,4NG5Y@976|Bacteroidetes,47K5X@768503|Cytophagia	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.23	ko:K09516	ko00830,map00830	-	R07163	RC01835	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
TLS3_k127_1553275_4	471854.Dfer_2001	1.769e-95	320.0	COG0204@1|root,COG0500@1|root,COG4258@1|root,COG0204@2|Bacteria,COG0500@2|Bacteria,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,47P2T@768503|Cytophagia	976|Bacteroidetes	I	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
TLS3_k127_1580828_5	755732.Fluta_1040	1.041e-19	90.0	COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,1IJBB@117743|Flavobacteriia,2PAC6@246874|Cryomorphaceae	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
TLS3_k127_1580828_0	755732.Fluta_1557	1.54e-130	433.0	COG1020@1|root,COG1020@2|Bacteria	2|Bacteria	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	AATase,Condensation,PapA_C
TLS3_k127_1580828_3	755732.Fluta_1037	6.453e-69	241.0	COG0670@1|root,COG0670@2|Bacteria,4NR2U@976|Bacteroidetes,1IJ0E@117743|Flavobacteriia,2PBR2@246874|Cryomorphaceae	976|Bacteroidetes	S	Inhibitor of apoptosis-promoting Bax1	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
TLS3_k127_1580828_1	755732.Fluta_1034	1.823e-90	301.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1HYCK@117743|Flavobacteriia,2PAYR@246874|Cryomorphaceae	976|Bacteroidetes	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
TLS3_k127_1580828_4	755732.Fluta_1033	2.751e-68	235.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1I8WV@117743|Flavobacteriia,2PBTR@246874|Cryomorphaceae	976|Bacteroidetes	H	TIGRFAM 6-pyruvoyl tetrahydropterin synthase QueD family protein	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
TLS3_k127_1580828_2	755732.Fluta_2082	1.924e-78	269.0	COG1189@1|root,COG1189@2|Bacteria	2|Bacteria	J	Ribosomal RNA methyltransferase RrmJ FtsJ	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
TLS3_k127_1580828_6	1218108.KB908295_gene1954	4.111e-16	79.0	COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,1HWSI@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
TLS3_k127_1583499_1	755732.Fluta_3497	1.738e-244	760.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia,2PAJ0@246874|Cryomorphaceae	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
TLS3_k127_1583499_4	755732.Fluta_3433	6.274e-65	229.0	2BUW8@1|root,32Q8B@2|Bacteria,4PBQS@976|Bacteroidetes,1ICQT@117743|Flavobacteriia,2PBTB@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1583499_3	755732.Fluta_3432	1.707e-179	569.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,1HWQ1@117743|Flavobacteriia,2PAFT@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
TLS3_k127_1583499_8	1121912.AUHD01000016_gene2915	1.732e-21	97.0	COG3093@1|root,COG3093@2|Bacteria,4NSDG@976|Bacteroidetes,1I3X0@117743|Flavobacteriia	976|Bacteroidetes	K	helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Phage_CI_repr
TLS3_k127_1583499_6	755732.Fluta_3426	4.265e-24	102.0	COG3530@1|root,COG3530@2|Bacteria,4NUSP@976|Bacteroidetes,1I50I@117743|Flavobacteriia,2PB97@246874|Cryomorphaceae	976|Bacteroidetes	S	Putative quorum-sensing-regulated virulence factor	-	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
TLS3_k127_1583499_2	755732.Fluta_3424	3.135e-210	662.0	COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,1HWUA@117743|Flavobacteriia,2PAB1@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_1583499_5	1279009.ADICEAN_03917	2.14e-24	104.0	COG4628@1|root,COG4628@2|Bacteria,4NUS1@976|Bacteroidetes,47RWW@768503|Cytophagia	976|Bacteroidetes	S	conserved protein (DUF2132)	-	-	-	-	-	-	-	-	-	-	-	-	VF530
TLS3_k127_1583499_0	755732.Fluta_3422	0.0	1004.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1HXQY@117743|Flavobacteriia,2PAKK@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM ATP-binding cassette protein, ChvD family	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_1583499_13	391603.FBALC1_11192	8.214e-13	71.0	2E372@1|root,32Y6U@2|Bacteria,4NUUI@976|Bacteroidetes,1I551@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
TLS3_k127_1583499_10	1121286.AUMT01000005_gene3070	2.389e-15	79.0	2DMKZ@1|root,32SAQ@2|Bacteria,4NS7K@976|Bacteroidetes,1I49R@117743|Flavobacteriia,3ZSC3@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MpPF26
TLS3_k127_1583499_12	649349.Lbys_0225	7.177e-13	75.0	2CBZZ@1|root,32QA1@2|Bacteria,4NQPJ@976|Bacteroidetes,47QN2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1583499_11	709991.Odosp_1618	4.139e-15	81.0	2CBZZ@1|root,32QA1@2|Bacteria,4NQPJ@976|Bacteroidetes,2FYEI@200643|Bacteroidia,230HI@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1589540_1	388413.ALPR1_14799	3.256e-87	294.0	COG0520@1|root,COG0520@2|Bacteria,4NJEQ@976|Bacteroidetes,47NQ3@768503|Cytophagia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
TLS3_k127_1589540_3	395019.Bmul_5343	1.159e-08	64.0	2CCI4@1|root,30BPJ@2|Bacteria,1RE42@1224|Proteobacteria,2W4MT@28216|Betaproteobacteria,1K7DA@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1589540_2	313595.P700755_003287	6.201e-44	177.0	COG0793@1|root,COG0793@2|Bacteria,4PJ39@976|Bacteroidetes,1IGBF@117743|Flavobacteriia,4C4DW@83612|Psychroflexus	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
TLS3_k127_1589540_0	1107311.Q767_13935	1.543e-93	312.0	COG0730@1|root,COG0730@2|Bacteria,4NFTT@976|Bacteroidetes,1HWXF@117743|Flavobacteriia,2NVT2@237|Flavobacterium	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_1594744_11	760192.Halhy_5135	8.475e-07	53.0	COG4733@1|root,COG4733@2|Bacteria,4NVQP@976|Bacteroidetes	976|Bacteroidetes	S	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
TLS3_k127_1594744_10	323097.Nham_3284	2.502e-07	61.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2U3FU@28211|Alphaproteobacteria,3JQSB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
TLS3_k127_1594744_7	1499968.TCA2_4094	3.976e-39	161.0	COG2132@1|root,COG3794@1|root,COG2132@2|Bacteria,COG3794@2|Bacteria,1TQJK@1239|Firmicutes,4IRUW@91061|Bacilli,26Z53@186822|Paenibacillaceae	91061|Bacilli	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
TLS3_k127_1594744_4	755732.Fluta_3394	8.823e-90	308.0	COG1858@1|root,COG1858@2|Bacteria,4NEKS@976|Bacteroidetes,1HZT9@117743|Flavobacteriia	976|Bacteroidetes	P	cytochrome C peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
TLS3_k127_1594744_2	755732.Fluta_3393	3.499e-138	442.0	COG4627@1|root,COG4627@2|Bacteria,4PP0V@976|Bacteroidetes,1IKE8@117743|Flavobacteriia,2PAIZ@246874|Cryomorphaceae	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_1594744_3	1122179.KB890445_gene4995	1.909e-91	325.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
TLS3_k127_1594744_9	313598.MED152_05055	5.21e-23	104.0	28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,1HYDM@117743|Flavobacteriia,3VWFS@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1594744_1	755732.Fluta_3389	1.082e-152	484.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,1HXAY@117743|Flavobacteriia,2PAIT@246874|Cryomorphaceae	976|Bacteroidetes	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
TLS3_k127_1594744_5	1286632.P278_08930	3.186e-69	236.0	COG0647@1|root,COG0647@2|Bacteria,4NNYH@976|Bacteroidetes,1I2FP@117743|Flavobacteriia	976|Bacteroidetes	G	Phosphoheptose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1594744_0	755732.Fluta_3388	7.872e-184	579.0	COG0247@1|root,COG0247@2|Bacteria,4PM9R@976|Bacteroidetes,1IJNY@117743|Flavobacteriia,2PACW@246874|Cryomorphaceae	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
TLS3_k127_1609326_6	755732.Fluta_2659	6.171e-55	194.0	COG4731@1|root,COG4731@2|Bacteria,4NQCK@976|Bacteroidetes,1I2T1@117743|Flavobacteriia,2PBYR@246874|Cryomorphaceae	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
TLS3_k127_1609326_4	755732.Fluta_2508	2.202e-69	244.0	COG2885@1|root,COG2885@2|Bacteria,4PBX6@976|Bacteroidetes,1IMRE@117743|Flavobacteriia,2PBP2@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
TLS3_k127_1609326_0	755732.Fluta_2505	0.0	1129.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,1HX0K@117743|Flavobacteriia,2PAG4@246874|Cryomorphaceae	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
TLS3_k127_1609326_2	755732.Fluta_0650	2.897e-212	665.0	2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,1HXI3@117743|Flavobacteriia,2PAEU@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1609326_1	755732.Fluta_0651	8.148e-222	698.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1HWS1@117743|Flavobacteriia,2PAKC@246874|Cryomorphaceae	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
TLS3_k127_1609326_5	1469557.JSWF01000012_gene1209	6.469e-59	213.0	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,1HZG3@117743|Flavobacteriia	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
TLS3_k127_1609326_3	1408433.JHXV01000021_gene1640	8.105e-172	546.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,1HWYI@117743|Flavobacteriia,2PAD9@246874|Cryomorphaceae	976|Bacteroidetes	J	Uncharacterized protein family UPF0004	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
TLS3_k127_1613782_3	1239962.C943_04007	2.744e-24	111.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_1613782_1	755732.Fluta_1909	4.362e-38	147.0	2DNED@1|root,30W9S@2|Bacteria,4P9NX@976|Bacteroidetes,1IE9S@117743|Flavobacteriia,2PBY6@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1613782_0	1408433.JHXV01000014_gene3643	1.05e-195	621.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1HX84@117743|Flavobacteriia,2PAH6@246874|Cryomorphaceae	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
TLS3_k127_1613782_4	269798.CHU_0597	3.137e-24	116.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Glyco_hydro_9,PKD,SprB
TLS3_k127_1613782_2	592029.DDD_1302	3.068e-29	130.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HXMP@117743|Flavobacteriia,3HJRD@363408|Nonlabens	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_1628882_17	1158338.JNLJ01000001_gene459	2.976e-13	82.0	29Y8Q@1|root,30K2F@2|Bacteria,2G5AG@200783|Aquificae	200783|Aquificae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1628882_11	385682.AFSL01000043_gene321	2.972e-39	164.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,2G2X9@200643|Bacteroidia,3XJH3@558415|Marinilabiliaceae	976|Bacteroidetes	CO	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
TLS3_k127_1628882_7	1270193.JARP01000003_gene1842	1.718e-66	250.0	COG3209@1|root,COG3291@1|root,COG4386@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4386@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia,2P0M9@237|Flavobacterium	976|Bacteroidetes	M	Galactose binding lectin domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gal_Lectin,HYR,Laminin_G_3,PKD,SprB,TSP_3
TLS3_k127_1628882_5	1166018.FAES_4609	1.276e-81	281.0	COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,47KAK@768503|Cytophagia	976|Bacteroidetes	S	PFAM O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
TLS3_k127_1628882_2	32049.SYNPCC7002_A2872	2.018e-177	575.0	COG2304@1|root,COG2304@2|Bacteria,1G3PE@1117|Cyanobacteria,1H2SF@1129|Synechococcus	1117|Cyanobacteria	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
TLS3_k127_1628882_0	1137281.D778_01099	0.0	1198.0	COG0160@1|root,COG2334@1|root,COG0160@2|Bacteria,COG2334@2|Bacteria,4NFMP@976|Bacteroidetes,1HZ97@117743|Flavobacteriia	976|Bacteroidetes	E	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
TLS3_k127_1628882_8	1121413.JMKT01000015_gene305	5.015e-65	231.0	COG0730@1|root,COG0730@2|Bacteria,1RBHH@1224|Proteobacteria,42R9E@68525|delta/epsilon subdivisions,2WNRJ@28221|Deltaproteobacteria,2MAXH@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_1628882_3	755732.Fluta_2831	1.117e-146	471.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,1HXBD@117743|Flavobacteriia,2PAK5@246874|Cryomorphaceae	976|Bacteroidetes	E	Beta-eliminating lyase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
TLS3_k127_1628882_10	1454007.JAUG01000072_gene4106	5.498e-44	165.0	COG2954@1|root,COG2954@2|Bacteria,4NNGE@976|Bacteroidetes,1ISZ5@117747|Sphingobacteriia	976|Bacteroidetes	S	CYTH	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
TLS3_k127_1628882_12	1408433.JHXV01000001_gene925	6.478e-38	154.0	COG5653@1|root,COG5653@2|Bacteria,4NQN5@976|Bacteroidetes,1I465@117743|Flavobacteriia,2PBWQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
TLS3_k127_1628882_6	755732.Fluta_2839	1.011e-76	263.0	COG1028@1|root,COG1028@2|Bacteria,4P4SC@976|Bacteroidetes,1I9Y5@117743|Flavobacteriia,2PBKR@246874|Cryomorphaceae	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_1628882_1	755732.Fluta_2840	5.723e-228	722.0	COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,1HWS6@117743|Flavobacteriia,2PAF1@246874|Cryomorphaceae	976|Bacteroidetes	GM	PFAM Polysaccharide biosynthesis protein	wbpM	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
TLS3_k127_1628882_13	755732.Fluta_2841	1.619e-33	133.0	COG0824@1|root,COG0824@2|Bacteria,4PKAH@976|Bacteroidetes,1I6XR@117743|Flavobacteriia,2PBX6@246874|Cryomorphaceae	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
TLS3_k127_1628882_4	755732.Fluta_2842	5.423e-87	299.0	COG2849@1|root,COG2849@2|Bacteria,4PG82@976|Bacteroidetes,1IMSM@117743|Flavobacteriia,2PBZD@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_1628882_9	1123277.KB893217_gene4624	2.011e-59	209.0	298UU@1|root,2ZVYZ@2|Bacteria,4NPH1@976|Bacteroidetes,47VIG@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_1628882_14	755732.Fluta_0203	7.928e-29	117.0	COG3668@1|root,COG3668@2|Bacteria,4PA83@976|Bacteroidetes,1IMTK@117743|Flavobacteriia,2PC54@246874|Cryomorphaceae	976|Bacteroidetes	S	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1628882_16	755732.Fluta_0024	6.779e-23	100.0	COG1434@1|root,COG1434@2|Bacteria,4NNYV@976|Bacteroidetes,1I706@117743|Flavobacteriia,2PBR6@246874|Cryomorphaceae	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
TLS3_k127_1629115_0	755732.Fluta_3344	2.5e-61	237.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia,2PBAT@246874|Cryomorphaceae	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
TLS3_k127_1629115_1	889378.Spiaf_0605	7.882e-14	76.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
TLS3_k127_1634167_2	1408433.JHXV01000002_gene432	3.063e-106	364.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gly_rich,PKD,SASA,SprB
TLS3_k127_1634167_4	1492738.FEM21_11600	1.012e-21	105.0	2CJFU@1|root,2Z8SP@2|Bacteria,4NI05@976|Bacteroidetes,1I2TI@117743|Flavobacteriia,2NWN3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1634167_0	1239962.C943_04248	1.392e-134	435.0	COG0823@1|root,COG0823@2|Bacteria,4NN6B@976|Bacteroidetes	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
TLS3_k127_1634167_1	1348583.ATLH01000011_gene356	5.102e-120	395.0	2CGBJ@1|root,311C6@2|Bacteria,4PG4R@976|Bacteroidetes,1IH0B@117743|Flavobacteriia,1FA43@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1634167_5	189426.PODO_00270	1.312e-08	61.0	COG0760@1|root,COG0760@2|Bacteria,1V6TT@1239|Firmicutes,4HJFR@91061|Bacilli,26QRB@186822|Paenibacillaceae	91061|Bacilli	M	peptidyl-prolyl isomerase	prsA1	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Cu_amine_oxidN1,Rotamase_3,SurA_N_3
TLS3_k127_1634167_3	984262.SGRA_1737	5.014e-57	223.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1IZUU@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
TLS3_k127_1638131_4	755732.Fluta_1438	9.747e-44	165.0	COG0304@1|root,COG0304@2|Bacteria,4NMSI@976|Bacteroidetes,1I1RZ@117743|Flavobacteriia,2PB55@246874|Cryomorphaceae	976|Bacteroidetes	IQ	3-oxoacyl-(ACP) synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1638131_6	755732.Fluta_1439	5.674e-34	131.0	COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes,1I3W1@117743|Flavobacteriia,2PB5J@246874|Cryomorphaceae	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TLS3_k127_1638131_0	755732.Fluta_1440	6.695e-168	535.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,1HY14@117743|Flavobacteriia,2PAJ6@246874|Cryomorphaceae	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_1638131_1	755732.Fluta_1441	3.522e-87	297.0	COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,1HXNF@117743|Flavobacteriia,2PB2I@246874|Cryomorphaceae	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2
TLS3_k127_1638131_2	1434325.AZQN01000002_gene731	6.862e-61	219.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,47QDV@768503|Cytophagia	976|Bacteroidetes	G	Polysaccharide deacetylase	pgdA	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	DUF3298,Polysacc_deac_1
TLS3_k127_1638131_3	755732.Fluta_1443	5.663e-46	174.0	COG2834@1|root,COG2834@2|Bacteria,4NT30@976|Bacteroidetes,1IM65@117743|Flavobacteriia,2PB89@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
TLS3_k127_1638131_7	575615.HMPREF0670_01516	4.817e-22	99.0	COG0764@1|root,COG0764@2|Bacteria,4NSGQ@976|Bacteroidetes,2FSPX@200643|Bacteroidia	976|Bacteroidetes	I	FabA-like domain	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
TLS3_k127_1638131_5	755732.Fluta_1445	1.566e-35	138.0	COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,4NETR@976|Bacteroidetes,1HY3M@117743|Flavobacteriia,2PAJZ@246874|Cryomorphaceae	976|Bacteroidetes	M	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DUF2062,Glycos_transf_2
TLS3_k127_1639334_2	797209.ZOD2009_19633	0.0001155	49.0	COG1520@1|root,arCOG02482@2157|Archaea,2XUI1@28890|Euryarchaeota,240TC@183963|Halobacteria	183963|Halobacteria	C	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
TLS3_k127_1639334_3	398512.JQKC01000001_gene2097	0.0002339	51.0	2D6GH@1|root,32TM6@2|Bacteria,1VNJY@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1639334_0	1408433.JHXV01000007_gene2924	6.116e-102	345.0	COG3325@1|root,COG3325@2|Bacteria	2|Bacteria	G	chitin binding	-	-	3.2.1.14,3.2.1.40	ko:K01183,ko:K05989	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,CBM_6,Glyco_hydro_18,Glyco_hydro_43,UnbV_ASPIC,VCBS
TLS3_k127_1639334_1	765910.MARPU_08655	8.4e-95	324.0	COG2138@1|root,COG2138@2|Bacteria,1QR0X@1224|Proteobacteria,1SMA5@1236|Gammaproteobacteria,1X002@135613|Chromatiales	135613|Chromatiales	S	CbiX	-	-	-	-	-	-	-	-	-	-	-	-	CbiX
TLS3_k127_16470_2	755732.Fluta_1332	2.658e-70	253.0	COG3735@1|root,COG3735@2|Bacteria,4NGNW@976|Bacteroidetes,1IGJW@117743|Flavobacteriia,2PC1R@246874|Cryomorphaceae	976|Bacteroidetes	S	TraB family	-	-	-	-	-	-	-	-	-	-	-	-	TraB
TLS3_k127_16470_1	755732.Fluta_1331	4.149e-87	302.0	COG1373@1|root,COG1373@2|Bacteria,4PIRN@976|Bacteroidetes,1ICV7@117743|Flavobacteriia,2PC1D@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
TLS3_k127_16470_0	755732.Fluta_1666	2.955e-210	682.0	COG3857@1|root,COG3857@2|Bacteria,4PKEH@976|Bacteroidetes,1IKDJ@117743|Flavobacteriia,2PACH@246874|Cryomorphaceae	976|Bacteroidetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Exonuc_V_gamma,PDDEXK_1
TLS3_k127_1667384_1	102129.Lepto7375DRAFT_7505	7.447e-28	122.0	COG2351@1|root,COG2351@2|Bacteria,1G4CU@1117|Cyanobacteria,1H7ZW@1150|Oscillatoriales	1117|Cyanobacteria	M	Salmonella virulence plasmid 28.1kDa A protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,VRP1
TLS3_k127_1667384_0	1296415.JACC01000030_gene2776	1.048e-245	805.0	COG3209@1|root,COG3209@2|Bacteria,4NF0G@976|Bacteroidetes,1I0VK@117743|Flavobacteriia	976|Bacteroidetes	M	RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midN
TLS3_k127_1677868_5	1122612.AUBA01000011_gene863	3.674e-05	55.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Cadherin_3,Calx-beta,DUF4347,FecR,He_PIG
TLS3_k127_1677868_0	755732.Fluta_0736	2.238e-258	814.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia,2PBCY@246874|Cryomorphaceae	976|Bacteroidetes	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS3_k127_1677868_3	755732.Fluta_0732	4.525e-129	425.0	COG0438@1|root,COG0438@2|Bacteria,4NG0D@976|Bacteroidetes,1I6W9@117743|Flavobacteriia	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_1677868_1	1279009.ADICEAN_03694	3.195e-152	486.0	COG0451@1|root,COG0451@2|Bacteria,4NKVH@976|Bacteroidetes,47TKC@768503|Cytophagia	976|Bacteroidetes	GM	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
TLS3_k127_1677868_2	984262.SGRA_1047	9.45e-133	432.0	COG0438@1|root,COG0438@2|Bacteria,4NJ6W@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
TLS3_k127_1677868_4	1250005.PHEL85_0830	7.747e-69	238.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,1I1CS@117743|Flavobacteriia,3VV3I@52959|Polaribacter	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
TLS3_k127_1692602_10	1313421.JHBV01000028_gene1857	3.663e-29	128.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
TLS3_k127_1692602_4	755732.Fluta_1228	2.249e-169	536.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1HXMS@117743|Flavobacteriia,2PAJI@246874|Cryomorphaceae	976|Bacteroidetes	I	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
TLS3_k127_1692602_3	755732.Fluta_0929	2.735e-171	546.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1HWT8@117743|Flavobacteriia,2PAIM@246874|Cryomorphaceae	976|Bacteroidetes	E	Amino acid kinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
TLS3_k127_1692602_11	755732.Fluta_1523	1.542e-13	73.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015684,GO:0030001,GO:0033554,GO:0034220,GO:0034755,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070627,GO:0070838,GO:0072511,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098707,GO:0098711,GO:0098739,GO:0099587,GO:1903874	-	ko:K03709,ko:K03711,ko:K04758,ko:K04759	-	-	-	-	ko00000,ko02000,ko03000	9.A.8.1	-	-	FeoA
TLS3_k127_1692602_1	313606.M23134_00387	2.291e-212	677.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
TLS3_k127_1692602_6	755732.Fluta_0493	3.373e-111	370.0	28IM1@1|root,2Z8MK@2|Bacteria,4NIZ0@976|Bacteroidetes,1HYU0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1692602_7	755732.Fluta_0494	5.022e-108	375.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,1IFXK@117743|Flavobacteriia,2PBNH@246874|Cryomorphaceae	976|Bacteroidetes	M	TIGRFAM C-terminal peptidase (prc)	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
TLS3_k127_1692602_0	755732.Fluta_1490	4.234e-222	701.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1HY8N@117743|Flavobacteriia,2PBUZ@246874|Cryomorphaceae	976|Bacteroidetes	G	Transporter	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
TLS3_k127_1692602_9	1380600.AUYN01000006_gene468	1.413e-86	295.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,4NGHV@976|Bacteroidetes,1HZ93@117743|Flavobacteriia	976|Bacteroidetes	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
TLS3_k127_1692602_5	1041826.FCOL_10765	4.617e-142	456.0	COG0329@1|root,COG0329@2|Bacteria,4NF2Z@976|Bacteroidetes,1I05Z@117743|Flavobacteriia,2NUXC@237|Flavobacterium	976|Bacteroidetes	EM	Belongs to the DapA family	-	-	3.5.4.22,4.3.3.7	ko:K01714,ko:K21062	ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02280,R10147	RC00679,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
TLS3_k127_1692602_2	143224.JQMD01000002_gene1165	1.624e-203	646.0	COG1012@1|root,COG1012@2|Bacteria,4NEKG@976|Bacteroidetes,1HX1F@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde	-	-	1.2.1.26,1.2.1.4	ko:K13877,ko:K14519	ko00040,ko00053,ko00930,ko01100,ko01120,ko01220,map00040,map00053,map00930,map01100,map01120,map01220	-	R00264,R05099	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
TLS3_k127_1692602_8	1270196.JCKI01000002_gene12	3.921e-90	301.0	COG3938@1|root,COG3938@2|Bacteria,4NHJZ@976|Bacteroidetes,1INXZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the proline racemase family	-	-	5.1.1.8	ko:K12658	ko00330,map00330	-	R03296	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
TLS3_k127_1705029_2	755732.Fluta_3612	3.514e-87	292.0	COG0577@1|root,COG0577@2|Bacteria,4NGDV@976|Bacteroidetes,1I2JK@117743|Flavobacteriia,2PBNA@246874|Cryomorphaceae	976|Bacteroidetes	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1705029_3	755732.Fluta_3611	4.208e-75	258.0	COG1136@1|root,COG1136@2|Bacteria,4NN5Z@976|Bacteroidetes,1I3IP@117743|Flavobacteriia,2PBN8@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_1705029_1	755732.Fluta_3610	5.877e-100	337.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,1HXKT@117743|Flavobacteriia,2PANG@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
TLS3_k127_1705029_0	755732.Fluta_3609	3.869e-155	501.0	COG4623@1|root,COG4623@2|Bacteria,4NHFW@976|Bacteroidetes,1HZYC@117743|Flavobacteriia,2PAMA@246874|Cryomorphaceae	976|Bacteroidetes	M	soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein	mltF	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
TLS3_k127_1706997_5	755732.Fluta_2678	6.968e-82	275.0	COG1704@1|root,COG1704@2|Bacteria,4NMP9@976|Bacteroidetes,1IG1E@117743|Flavobacteriia,2PBXC@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
TLS3_k127_1706997_4	755732.Fluta_2677	1.204e-118	388.0	COG0501@1|root,COG0501@2|Bacteria,4NESF@976|Bacteroidetes,1HWMY@117743|Flavobacteriia	976|Bacteroidetes	O	Zn-dependent protease with chaperone function	-	-	3.4.24.84	ko:K03799,ko:K06013	ko00900,ko01130,map00900,map01130	M00743	R09845	RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
TLS3_k127_1706997_7	269798.CHU_0700	2.218e-50	183.0	COG2010@1|root,COG2010@2|Bacteria,4NQN1@976|Bacteroidetes,47XSN@768503|Cytophagia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
TLS3_k127_1706997_0	755732.Fluta_1469	2.934e-189	597.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1HX73@117743|Flavobacteriia,2PA8W@246874|Cryomorphaceae	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
TLS3_k127_1706997_3	153721.MYP_1780	1.589e-126	421.0	COG1570@1|root,COG1570@2|Bacteria,4NE64@976|Bacteroidetes,47NEW@768503|Cytophagia	976|Bacteroidetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
TLS3_k127_1706997_1	1122176.KB903587_gene4484	1.822e-172	558.0	COG2234@1|root,COG2234@2|Bacteria,4NENF@976|Bacteroidetes,1IPRF@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
TLS3_k127_1706997_8	153721.MYP_1779	6.343e-19	87.0	COG1722@1|root,COG1722@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
TLS3_k127_1706997_6	755732.Fluta_1489	3.189e-81	276.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1HXP2@117743|Flavobacteriia,2PAWG@246874|Cryomorphaceae	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
TLS3_k127_1706997_2	1408433.JHXV01000008_gene171	1.583e-157	499.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1HWZT@117743|Flavobacteriia,2PBBI@246874|Cryomorphaceae	976|Bacteroidetes	E	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
TLS3_k127_1742853_2	1120965.AUBV01000004_gene887	2.416e-13	74.0	COG3299@1|root,COG3299@2|Bacteria,4NF69@976|Bacteroidetes,47N9M@768503|Cytophagia	976|Bacteroidetes	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
TLS3_k127_1742853_1	1443665.JACA01000013_gene4231	1.433e-28	120.0	COG3628@1|root,COG3628@2|Bacteria,4NSKN@976|Bacteroidetes,1I48Y@117743|Flavobacteriia,2YJZ4@290174|Aquimarina	976|Bacteroidetes	S	Gene 25-like lysozyme	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
TLS3_k127_1742853_3	1469607.KK073769_gene5929	6.385e-10	63.0	COG4104@1|root,COG4104@2|Bacteria,1GIRZ@1117|Cyanobacteria,1HPH6@1161|Nostocales	1117|Cyanobacteria	S	PFAM PAAR motif	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
TLS3_k127_1742853_0	1296415.JACC01000011_gene544	5.56e-72	263.0	COG3501@1|root,COG3501@2|Bacteria,4NFPB@976|Bacteroidetes,1HZN7@117743|Flavobacteriia,2YM49@290174|Aquimarina	976|Bacteroidetes	S	Rhs element Vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
TLS3_k127_174720_3	755732.Fluta_2042	1.096e-104	351.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,1HWPY@117743|Flavobacteriia,2PAQP@246874|Cryomorphaceae	976|Bacteroidetes	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
TLS3_k127_174720_4	755732.Fluta_0076	7.942e-83	285.0	COG0583@1|root,COG0583@2|Bacteria,4NGZ5@976|Bacteroidetes,1HXGU@117743|Flavobacteriia,2PAYB@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Bacterial regulatory helix-turn-helix protein, lysR family	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
TLS3_k127_174720_5	755732.Fluta_0077	2.394e-59	208.0	COG0783@1|root,COG0783@2|Bacteria,4NQDD@976|Bacteroidetes,1I1BH@117743|Flavobacteriia,2PAXB@246874|Cryomorphaceae	976|Bacteroidetes	P	DNA-binding ferritin-like protein (Oxidative damage protectant)	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
TLS3_k127_174720_2	929556.Solca_0238	1.544e-105	347.0	COG0450@1|root,COG0450@2|Bacteria,4NEDT@976|Bacteroidetes,1IPHX@117747|Sphingobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
TLS3_k127_174720_0	926562.Oweho_2000	2.832e-149	483.0	COG1914@1|root,COG1914@2|Bacteria,4NEG8@976|Bacteroidetes,1HYMN@117743|Flavobacteriia	976|Bacteroidetes	P	Mn2 and Fe2 transporters of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
TLS3_k127_174720_1	926562.Oweho_2899	8.598e-106	352.0	COG2031@1|root,COG2031@2|Bacteria,4NIRP@976|Bacteroidetes,1HWM3@117743|Flavobacteriia	976|Bacteroidetes	I	Short chain fatty acid transporter	atoE	-	-	ko:K02106	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.73.1	-	-	SCFA_trans
TLS3_k127_178161_1	755732.Fluta_0303	1.294e-191	626.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,1HZTJ@117743|Flavobacteriia,2PAS8@246874|Cryomorphaceae	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
TLS3_k127_178161_3	1408433.JHXV01000014_gene3696	1.785e-174	551.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,1HWK5@117743|Flavobacteriia,2PA7R@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
TLS3_k127_178161_4	471854.Dfer_0246	4.034e-122	401.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,47K5N@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
TLS3_k127_178161_2	926562.Oweho_2631	5.511e-185	602.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,1HXNJ@117743|Flavobacteriia,2PAJW@246874|Cryomorphaceae	976|Bacteroidetes	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
TLS3_k127_178161_0	1408433.JHXV01000001_gene667	0.0	1055.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,4NI68@976|Bacteroidetes,1HXAQ@117743|Flavobacteriia,2PA5C@246874|Cryomorphaceae	976|Bacteroidetes	CI	TIGRFAM phenylacetic acid degradation protein paaN	paaN	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,DUF1569,MaoC_dehydratas
TLS3_k127_178161_5	755732.Fluta_0866	9.514e-35	145.0	COG2913@1|root,COG2913@2|Bacteria,4NP4N@976|Bacteroidetes,1I2RK@117743|Flavobacteriia	976|Bacteroidetes	J	Domain of unknown function (DUF4476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4476,SmpA_OmlA
TLS3_k127_1788744_1	600809.BPLAN_573	8.497e-46	168.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,1HXKA@117743|Flavobacteriia,3IV86@39782|Blattabacteriaceae	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS3_k127_1788744_0	1313421.JHBV01000008_gene4454	5.528e-66	228.0	COG1522@1|root,COG1522@2|Bacteria,4NNH2@976|Bacteroidetes	976|Bacteroidetes	K	AsnC family	lrp	-	-	ko:K03719,ko:K05800	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
TLS3_k127_1795221_1	755732.Fluta_3905	8.667e-114	374.0	COG0265@1|root,COG3673@1|root,COG0265@2|Bacteria,COG3673@2|Bacteria,4PNUK@976|Bacteroidetes,1IKEA@117743|Flavobacteriia,2PA7S@246874|Cryomorphaceae	976|Bacteroidetes	O	Peptide-N-glycosidase F, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,N-glycanase_C
TLS3_k127_1795221_2	755732.Fluta_4032	1.275e-102	347.0	COG1835@1|root,COG1835@2|Bacteria,4PIH2@976|Bacteroidetes,1IGD6@117743|Flavobacteriia,2PBU2@246874|Cryomorphaceae	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS3_k127_1795221_0	755732.Fluta_4031	1.057e-205	646.0	COG0579@1|root,COG0579@2|Bacteria,4NE0B@976|Bacteroidetes,1HZQJ@117743|Flavobacteriia,2PACG@246874|Cryomorphaceae	976|Bacteroidetes	S	FAD dependent oxidoreductase	lhgO	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
TLS3_k127_1795221_4	1380384.JADN01000004_gene2218	1.641e-85	294.0	COG0628@1|root,COG0628@2|Bacteria,4NHP4@976|Bacteroidetes,1HXG6@117743|Flavobacteriia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS3_k127_1795221_3	1356852.N008_05740	2.421e-93	313.0	COG2021@1|root,COG2021@2|Bacteria,4NFG2@976|Bacteroidetes,47KMZ@768503|Cytophagia	976|Bacteroidetes	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
TLS3_k127_1862679_1	755732.Fluta_2440	2.118e-227	709.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,1HWP1@117743|Flavobacteriia,2PAIG@246874|Cryomorphaceae	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
TLS3_k127_1862679_3	755732.Fluta_2441	1.126e-137	454.0	COG1934@1|root,COG1934@2|Bacteria,4PKT4@976|Bacteroidetes,1IKDV@117743|Flavobacteriia,2PAQU@246874|Cryomorphaceae	976|Bacteroidetes	S	OstA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OstA_2
TLS3_k127_1862679_5	755732.Fluta_1301	5.393e-12	76.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_1862679_0	755732.Fluta_2437	0.0	1119.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1HX98@117743|Flavobacteriia,2PAE3@246874|Cryomorphaceae	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
TLS3_k127_1862679_2	755732.Fluta_2435	1.17e-198	627.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes,1HXN9@117743|Flavobacteriia,2PBAS@246874|Cryomorphaceae	976|Bacteroidetes	Q	Fumarylacetoacetate (FAA) hydrolase family	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
TLS3_k127_1862679_4	755732.Fluta_0143	1.385e-104	342.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,1HWMK@117743|Flavobacteriia,2PA91@246874|Cryomorphaceae	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
TLS3_k127_1867316_5	755732.Fluta_2481	4.254e-94	327.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia,2PA9P@246874|Cryomorphaceae	976|Bacteroidetes	L	UvrD/REP helicase N-terminal domain	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
TLS3_k127_1867316_9	755732.Fluta_2482	6.405e-55	202.0	2DX5Q@1|root,343H0@2|Bacteria,4P5PC@976|Bacteroidetes,1IA62@117743|Flavobacteriia,2PB79@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1867316_2	755732.Fluta_2483	1.17e-161	515.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1HXUF@117743|Flavobacteriia,2PBJ7@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
TLS3_k127_1867316_0	755732.Fluta_2484	2.097e-240	749.0	COG1057@1|root,COG1057@2|Bacteria,4NEIR@976|Bacteroidetes,1HWWY@117743|Flavobacteriia,2PAKX@246874|Cryomorphaceae	976|Bacteroidetes	H	Nicotinate-nucleotide adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1867316_3	755732.Fluta_2486	2.075e-115	380.0	COG2378@1|root,COG2378@2|Bacteria,4NGHM@976|Bacteroidetes,1IIYK@117743|Flavobacteriia,2PBCB@246874|Cryomorphaceae	976|Bacteroidetes	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
TLS3_k127_1867316_8	760192.Halhy_5350	8.332e-61	219.0	COG3963@1|root,COG3963@2|Bacteria,4PP1W@976|Bacteroidetes,1IXSI@117747|Sphingobacteriia	976|Bacteroidetes	I	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
TLS3_k127_1867316_4	755732.Fluta_2489	1.314e-114	374.0	COG1024@1|root,COG1024@2|Bacteria,4NHRF@976|Bacteroidetes,1HXUI@117743|Flavobacteriia,2PA7H@246874|Cryomorphaceae	976|Bacteroidetes	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
TLS3_k127_1867316_10	880071.Fleli_2182	2.44e-51	196.0	COG2204@1|root,COG2208@1|root,COG2204@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	srrB	-	3.1.3.3	ko:K02490,ko:K07315,ko:K20971	ko02020,ko02024,ko02025,map02020,map02024,map02025	M00485	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021	-	-	-	CBS,GAF_2,HAMP,Response_reg,SpoIIE,Y_Y_Y,dCache_1
TLS3_k127_1867316_1	755732.Fluta_2490	1.051e-170	542.0	COG1250@1|root,COG1250@2|Bacteria,4NF2W@976|Bacteroidetes,1HXCF@117743|Flavobacteriia,2PADF@246874|Cryomorphaceae	976|Bacteroidetes	C	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
TLS3_k127_1867316_12	398720.MED217_06611	7.321e-16	87.0	COG2197@1|root,COG2197@2|Bacteria,4NQZ6@976|Bacteroidetes,1HZDI@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_3
TLS3_k127_1867316_6	755732.Fluta_0056	2.809e-88	304.0	COG0790@1|root,COG0790@2|Bacteria,4NQ0M@976|Bacteroidetes	976|Bacteroidetes	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1867316_7	755732.Fluta_0055	2.718e-70	244.0	COG5395@1|root,COG5395@2|Bacteria,4NMDY@976|Bacteroidetes	976|Bacteroidetes	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
TLS3_k127_1867316_11	755732.Fluta_0054	2.315e-42	165.0	2BVQT@1|root,333K1@2|Bacteria,4NX2M@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_18691_3	1408433.JHXV01000004_gene3381	7.112e-133	445.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia,2PBHG@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
TLS3_k127_18691_4	760192.Halhy_5684	1.008e-79	272.0	COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,1ISDK@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_18691_0	760192.Halhy_5663	8.622e-249	795.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes	976|Bacteroidetes	T	histidine kinase-, DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,Guanylate_cyc,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,TPR_12
TLS3_k127_18691_5	1131812.JQMS01000001_gene2389	1.699e-67	231.0	COG2204@1|root,COG2204@2|Bacteria,4NR03@976|Bacteroidetes,1IKSJ@117743|Flavobacteriia,2P0VE@237|Flavobacterium	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_18691_6	755732.Fluta_0652	5.963e-63	225.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
TLS3_k127_18691_17	1131812.JQMS01000001_gene2364	1.224e-08	61.0	2DH3W@1|root,2ZYAK@2|Bacteria,4PCVZ@976|Bacteroidetes,1IDDT@117743|Flavobacteriia,2NY3B@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_18691_9	616991.JPOO01000003_gene619	2.366e-38	146.0	COG1393@1|root,COG1393@2|Bacteria,4NSWE@976|Bacteroidetes,1I56N@117743|Flavobacteriia,23HPA@178469|Arenibacter	976|Bacteroidetes	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
TLS3_k127_18691_16	1121440.AUMA01000010_gene363	1.412e-09	61.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKYI@28221|Deltaproteobacteria,2MA7Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	response regulator, receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
TLS3_k127_18691_12	235909.GK3150	8.071e-25	110.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HA3V@91061|Bacilli,1WE7Q@129337|Geobacillus	91061|Bacilli	K	helix_turn_helix, Lux Regulon	degU	-	-	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	M00478	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
TLS3_k127_18691_10	929562.Emtol_3052	9.489e-35	149.0	COG4585@1|root,COG4585@2|Bacteria,4NMRZ@976|Bacteroidetes,47QIU@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA_3
TLS3_k127_18691_2	313596.RB2501_12062	8.216e-141	452.0	COG0668@1|root,COG0668@2|Bacteria,4NFHD@976|Bacteroidetes,1HYUW@117743|Flavobacteriia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
TLS3_k127_18691_1	865937.Gilli_1491	2.211e-190	602.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1HYW2@117743|Flavobacteriia,2P78T@244698|Gillisia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
TLS3_k127_18691_8	391598.FBBAL38_09094	1.013e-48	176.0	2C0VV@1|root,32R2M@2|Bacteria,4NQM5@976|Bacteroidetes,1I3U1@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_18691_15	762903.Pedsa_1767	3.725e-11	65.0	COG3462@1|root,COG3462@2|Bacteria,4NVJQ@976|Bacteroidetes,1ITX7@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
TLS3_k127_18691_7	760192.Halhy_1784	1.81e-56	201.0	COG0783@1|root,COG0783@2|Bacteria,4NNG4@976|Bacteroidetes,1ISE0@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
TLS3_k127_18691_14	1121890.AUDO01000007_gene2441	6.26e-15	81.0	2DRAU@1|root,33B03@2|Bacteria,4NXX1@976|Bacteroidetes,1ID8H@117743|Flavobacteriia,2NXQB@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_18691_13	1392488.JHZY01000002_gene1056	5.576e-24	102.0	COG3462@1|root,COG3462@2|Bacteria,4PA0Y@976|Bacteroidetes,1IE08@117743|Flavobacteriia,2XKES@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
TLS3_k127_18691_11	1392490.JHZX01000001_gene683	3.799e-32	127.0	2DP1T@1|root,3306B@2|Bacteria,4NVIV@976|Bacteroidetes,1I9MX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1876179_0	755732.Fluta_2922	0.0	1543.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1HXC3@117743|Flavobacteriia,2PAKG@246874|Cryomorphaceae	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
TLS3_k127_1876179_1	1336803.PHEL49_1996	6.542e-37	147.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,1HZIC@117743|Flavobacteriia,3VUZS@52959|Polaribacter	976|Bacteroidetes	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
TLS3_k127_1905598_2	1469557.JSWF01000031_gene1988	5.772e-24	109.0	2C4T4@1|root,32REG@2|Bacteria,4NQXB@976|Bacteroidetes,1I8H2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1905598_1	1168034.FH5T_03525	7.54e-58	219.0	COG3307@1|root,COG3307@2|Bacteria,4NMYT@976|Bacteroidetes	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
TLS3_k127_1905598_4	755732.Fluta_1728	9.294e-15	85.0	COG3206@1|root,COG3206@2|Bacteria,4NWAG@976|Bacteroidetes,1I785@117743|Flavobacteriia,2PAYX@246874|Cryomorphaceae	976|Bacteroidetes	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
TLS3_k127_1905598_0	1122176.KB903538_gene1446	1.65e-85	301.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_1905598_3	1461577.CCMH01000009_gene1448	1.078e-17	89.0	COG0560@1|root,COG0560@2|Bacteria,4NMFA@976|Bacteroidetes,1I1V6@117743|Flavobacteriia	976|Bacteroidetes	E	HAD family hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
TLS3_k127_1936884_3	755732.Fluta_3502	3.056e-65	228.0	COG0589@1|root,COG0589@2|Bacteria,4NWVX@976|Bacteroidetes,1ICQI@117743|Flavobacteriia,2PBRT@246874|Cryomorphaceae	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_1936884_1	929562.Emtol_4256	7.951e-83	283.0	COG2996@1|root,COG2996@2|Bacteria,4NGS6@976|Bacteroidetes,47KDR@768503|Cytophagia	976|Bacteroidetes	S	S1 domain	yitL	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
TLS3_k127_1936884_0	755732.Fluta_3505	2.146e-107	352.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,1HXVN@117743|Flavobacteriia,2PBFF@246874|Cryomorphaceae	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_1936884_2	755732.Fluta_3506	1.801e-75	265.0	COG2972@1|root,COG2972@2|Bacteria,4NI09@976|Bacteroidetes,1I10Z@117743|Flavobacteriia,2PBKU@246874|Cryomorphaceae	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_1936884_4	755732.Fluta_3507	1.137e-60	222.0	2E074@1|root,32VV1@2|Bacteria,4NTTK@976|Bacteroidetes	976|Bacteroidetes	S	Bacterial toxin 23	-	-	-	-	-	-	-	-	-	-	-	-	Ntox23
TLS3_k127_1936884_5	1408433.JHXV01000005_gene2361	1.474e-21	106.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1HY2Q@117743|Flavobacteriia,2PBZ4@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_3,Kelch_4,Kelch_6
TLS3_k127_1953683_0	1107311.Q767_00390	1.977e-33	147.0	COG1520@1|root,COG3386@1|root,COG5306@1|root,COG1520@2|Bacteria,COG3386@2|Bacteria,COG5306@2|Bacteria,4PPGQ@976|Bacteroidetes,1IKMC@117743|Flavobacteriia,2NUKU@237|Flavobacterium	976|Bacteroidetes	G	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
TLS3_k127_1953683_1	714961.BFZC1_09655	3.222e-06	49.0	COG2197@1|root,COG2197@2|Bacteria,1VGRH@1239|Firmicutes,4HQYG@91061|Bacilli,3IZJ0@400634|Lysinibacillus	91061|Bacilli	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
TLS3_k127_1987183_5	667015.Bacsa_1485	2.535e-08	55.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,2FN1T@200643|Bacteroidia,4AKHH@815|Bacteroidaceae	976|Bacteroidetes	H	Psort location Cytoplasmic, score 8.96	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
TLS3_k127_1987183_6	1121889.AUDM01000007_gene930	0.0002042	49.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.121	ko:K07004,ko:K20755	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Exo_endo_phos,LTD,Omp28,Peptidase_M14
TLS3_k127_1987183_1	755732.Fluta_3995	4.221e-92	312.0	COG2515@1|root,COG2515@2|Bacteria,4NEP9@976|Bacteroidetes,1HXPQ@117743|Flavobacteriia,2PARU@246874|Cryomorphaceae	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	acdS	-	3.5.99.7	ko:K01505	ko00270,map00270	-	R00997	RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
TLS3_k127_1987183_4	755732.Fluta_3996	8.254e-22	95.0	2E5CT@1|root,3304V@2|Bacteria,4NUT2@976|Bacteroidetes,1II8Q@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1987183_3	755732.Fluta_4000	3.113e-75	257.0	COG0204@1|root,COG0204@2|Bacteria,4NNG7@976|Bacteroidetes,1I28N@117743|Flavobacteriia,2PBYI@246874|Cryomorphaceae	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TLS3_k127_1987183_2	929556.Solca_1125	1.284e-81	280.0	COG0614@1|root,COG0614@2|Bacteria,4NI2Y@976|Bacteroidetes,1IPYQ@117747|Sphingobacteriia	976|Bacteroidetes	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	fecB	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
TLS3_k127_1987183_0	755732.Fluta_4004	1.48e-112	367.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,4NDZ9@976|Bacteroidetes,1HX7P@117743|Flavobacteriia,2PACD@246874|Cryomorphaceae	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
TLS3_k127_201582_1	755732.Fluta_0615	1.908e-84	283.0	28M4Q@1|root,2ZAIK@2|Bacteria,4NJC3@976|Bacteroidetes,1IMPU@117743|Flavobacteriia,2PATN@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_201582_2	755732.Fluta_0614	4.614e-44	171.0	2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia,2PBW4@246874|Cryomorphaceae	976|Bacteroidetes	S	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
TLS3_k127_201582_4	755732.Fluta_0613	3.705e-15	79.0	COG2010@1|root,COG2010@2|Bacteria,4PBRC@976|Bacteroidetes,1ID61@117743|Flavobacteriia,2PBA0@246874|Cryomorphaceae	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_201582_3	755732.Fluta_0610	1.265e-41	156.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1HXMD@117743|Flavobacteriia,2PAYC@246874|Cryomorphaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_20206_2	1239962.C943_02859	2.302e-52	186.0	2E00E@1|root,32VPV@2|Bacteria,4NSNA@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_20206_1	269798.CHU_3520	0.0	1176.0	COG0475@1|root,COG0475@2|Bacteria,4NFPE@976|Bacteroidetes,47NZK@768503|Cytophagia	976|Bacteroidetes	P	Sodium/hydrogen exchanger family	nhaS3	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
TLS3_k127_20206_3	714943.Mucpa_2809	0.0005033	50.0	COG2353@1|root,COG2353@2|Bacteria,4NT3W@976|Bacteroidetes,1IUC5@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_20206_0	755732.Fluta_2383	0.0	1787.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,1HYCE@117743|Flavobacteriia,2PBBZ@246874|Cryomorphaceae	976|Bacteroidetes	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
TLS3_k127_2034939_0	755732.Fluta_0828	1.233e-70	240.0	COG0492@1|root,COG0492@2|Bacteria,4NEQM@976|Bacteroidetes,1HWUC@117743|Flavobacteriia,2PBCP@246874|Cryomorphaceae	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_2034939_1	319236.JCM19294_1948	1.872e-63	237.0	COG3250@1|root,COG3250@2|Bacteria,4NE9C@976|Bacteroidetes,1HYIU@117743|Flavobacteriia,3HKUB@363408|Nonlabens	976|Bacteroidetes	G	Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
TLS3_k127_2034939_2	1408433.JHXV01000002_gene334	8.804e-18	96.0	COG2374@1|root,COG4935@1|root,COG2374@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,LTD,SLH
TLS3_k127_2035883_10	1123037.AUDE01000026_gene2055	2.083e-05	47.0	COG3476@1|root,COG3476@2|Bacteria,4NP0D@976|Bacteroidetes,1I2B8@117743|Flavobacteriia	976|Bacteroidetes	T	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
TLS3_k127_2035883_3	1347342.BN863_4090	9.881e-175	557.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,1HXRR@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
TLS3_k127_2035883_8	484770.UFO1_3441	4.762e-35	138.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
TLS3_k127_2035883_5	391603.FBALC1_06513	6.8e-99	330.0	COG2819@1|root,COG2819@2|Bacteria,4NGAG@976|Bacteroidetes,1HZR3@117743|Flavobacteriia	976|Bacteroidetes	S	Esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
TLS3_k127_2035883_1	1121912.AUHD01000005_gene1847	5.202e-205	649.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1HWMZ@117743|Flavobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Beta-lactamase2,DUF3471
TLS3_k127_2035883_7	313595.P700755_003391	4.323e-48	181.0	COG3542@1|root,COG3542@2|Bacteria,4NPCH@976|Bacteroidetes,1I2JW@117743|Flavobacteriia,4C3P6@83612|Psychroflexus	976|Bacteroidetes	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
TLS3_k127_2035883_6	755732.Fluta_0117	6.971e-76	261.0	COG1434@1|root,COG1434@2|Bacteria,4NNUT@976|Bacteroidetes,1ICMW@117743|Flavobacteriia,2PAZM@246874|Cryomorphaceae	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
TLS3_k127_2035883_4	755732.Fluta_2734	1.074e-147	477.0	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,1HZBE@117743|Flavobacteriia,2PAQB@246874|Cryomorphaceae	976|Bacteroidetes	L	THUMP	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
TLS3_k127_2035883_0	755732.Fluta_2733	1.418e-245	781.0	COG1752@1|root,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,1HWZP@117743|Flavobacteriia,2PBJS@246874|Cryomorphaceae	976|Bacteroidetes	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	POTRA,Patatin
TLS3_k127_2035883_2	1408433.JHXV01000005_gene2300	9.155e-175	553.0	COG0346@1|root,COG0346@2|Bacteria,4NDVG@976|Bacteroidetes,1HXW5@117743|Flavobacteriia,2PAFU@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
TLS3_k127_2035883_9	755732.Fluta_2731	6.216e-15	79.0	2CA1R@1|root,32FVT@2|Bacteria,4PBTZ@976|Bacteroidetes,1I9V5@117743|Flavobacteriia,2PBA8@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
TLS3_k127_2047128_2	926562.Oweho_0356	2.402e-82	289.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HWJR@117743|Flavobacteriia,2PBB9@246874|Cryomorphaceae	976|Bacteroidetes	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Peptidase_M43
TLS3_k127_2047128_3	445970.ALIPUT_00376	3.865e-55	205.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,4NGHH@976|Bacteroidetes,2FMHT@200643|Bacteroidia,22U0W@171550|Rikenellaceae	976|Bacteroidetes	M	Lysin motif	mepM_1	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
TLS3_k127_2047128_5	700598.Niako_5262	0.0001615	51.0	COG1520@1|root,COG1520@2|Bacteria,4NZ4G@976|Bacteroidetes	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2047128_4	755732.Fluta_2868	5.871e-25	106.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,1IG8B@117743|Flavobacteriia,2PBXI@246874|Cryomorphaceae	976|Bacteroidetes	P	PFAM Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS3_k127_2047128_1	742766.HMPREF9455_02820	6.755e-92	307.0	COG0564@1|root,COG0564@2|Bacteria,4NFS8@976|Bacteroidetes,2FN9G@200643|Bacteroidia,22WC3@171551|Porphyromonadaceae	976|Bacteroidetes	J	Pseudouridine synthase	rluC	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
TLS3_k127_2047128_0	755732.Fluta_2879	3.029e-141	452.0	COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,1HXEE@117743|Flavobacteriia,2PAFE@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
TLS3_k127_2077381_4	1122176.KB903569_gene3483	7.922e-68	248.0	COG5337@1|root,COG5337@2|Bacteria,4NEH2@976|Bacteroidetes	976|Bacteroidetes	M	sodium ion export across plasma membrane	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
TLS3_k127_2077381_9	755732.Fluta_1891	9.758e-16	81.0	2DGVM@1|root,2ZXFN@2|Bacteria,4P8FH@976|Bacteroidetes,1IMT9@117743|Flavobacteriia,2PC3X@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2077381_10	641491.DND132_2086	8.26e-09	68.0	COG0457@1|root,COG0457@2|Bacteria,1PZB5@1224|Proteobacteria,435VA@68525|delta/epsilon subdivisions,2X0AW@28221|Deltaproteobacteria,2MBKQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
TLS3_k127_2077381_6	1121930.AQXG01000001_gene1217	7.346e-26	113.0	2CM2H@1|root,32SDI@2|Bacteria,4NSAF@976|Bacteroidetes,1IUA8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
TLS3_k127_2077381_8	760192.Halhy_1033	8.443e-17	91.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	PMT_2
TLS3_k127_2077381_3	1408433.JHXV01000032_gene1133	3.711e-80	273.0	COG1807@1|root,COG1807@2|Bacteria,4PG9X@976|Bacteroidetes,1IMRA@117743|Flavobacteriia,2PBNI@246874|Cryomorphaceae	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_2077381_5	67373.JOBF01000002_gene1249	3.12e-27	127.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,PD40,PQQ_2
TLS3_k127_2077381_11	1121889.AUDM01000025_gene4	6.921e-06	59.0	COG1345@1|root,COG3291@1|root,COG3391@1|root,COG1345@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,2NSFX@237|Flavobacterium	976|Bacteroidetes	N	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_2077381_7	1484460.JSWG01000009_gene518	6.967e-21	107.0	COG2234@1|root,COG5306@1|root,COG2234@2|Bacteria,COG5306@2|Bacteria,4NKK9@976|Bacteroidetes,1IJRY@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M28
TLS3_k127_2077381_1	1189620.AJXL01000007_gene2326	2.222e-106	355.0	COG0709@1|root,COG2603@1|root,COG0709@2|Bacteria,COG2603@2|Bacteria,4NI4R@976|Bacteroidetes,1I7IF@117743|Flavobacteriia	976|Bacteroidetes	E	AIR synthase related protein, N-terminal domain	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
TLS3_k127_2077381_0	869213.JCM21142_1701	4.422e-149	478.0	COG0709@1|root,COG0709@2|Bacteria,4NI4R@976|Bacteroidetes,47JJA@768503|Cytophagia	976|Bacteroidetes	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
TLS3_k127_2077381_2	655815.ZPR_1992	7.884e-90	305.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,1HYK9@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M1	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
TLS3_k127_2092958_3	1313421.JHBV01000030_gene2179	4.051e-139	455.0	COG2010@1|root,COG2010@2|Bacteria,4NEEJ@976|Bacteroidetes,1IP2H@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,FlgD_ig
TLS3_k127_2092958_10	755732.Fluta_1724	5.821e-32	127.0	2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,1I425@117743|Flavobacteriia,2PB6J@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4286)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4286
TLS3_k127_2092958_5	755732.Fluta_1723	8.114e-105	346.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,1HXMG@117743|Flavobacteriia,2PAPI@246874|Cryomorphaceae	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
TLS3_k127_2092958_13	1453500.AT05_07820	8.084e-08	56.0	2FKST@1|root,34CDA@2|Bacteria,4P8GZ@976|Bacteroidetes,1IBC5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2092958_8	1168289.AJKI01000002_gene2285	1.592e-62	221.0	COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,2FM5H@200643|Bacteroidia,3XJN0@558415|Marinilabiliaceae	976|Bacteroidetes	I	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
TLS3_k127_2092958_1	755732.Fluta_1600	4.841e-171	540.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,1HX0S@117743|Flavobacteriia,2PAI3@246874|Cryomorphaceae	976|Bacteroidetes	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
TLS3_k127_2092958_12	755732.Fluta_3054	1.472e-16	91.0	COG3755@1|root,COG3755@2|Bacteria	2|Bacteria	S	Lysozyme inhibitor LprI	-	-	-	-	-	-	-	-	-	-	-	-	LprI
TLS3_k127_2092958_6	755732.Fluta_1726	2.452e-87	292.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,1HYXC@117743|Flavobacteriia,2PAPW@246874|Cryomorphaceae	976|Bacteroidetes	H	Lumazine binding domain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
TLS3_k127_2092958_4	755732.Fluta_0390	9.836e-129	427.0	2A8PB@1|root,30XRW@2|Bacteria,4PB9W@976|Bacteroidetes,1IMQZ@117743|Flavobacteriia,2PBHI@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2092958_2	1408433.JHXV01000006_gene2637	1.977e-156	506.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia,2PBCE@246874|Cryomorphaceae	976|Bacteroidetes	M	membrane protein involved in D-alanine export	algI	-	-	-	-	-	-	-	-	-	-	-	MBOAT
TLS3_k127_2092958_0	1122176.KB903532_gene2517	0.0	1380.0	COG3383@1|root,COG3383@2|Bacteria,4PKV4@976|Bacteroidetes,1IX2V@117747|Sphingobacteriia	976|Bacteroidetes	C	TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type	hndD	-	1.12.1.3,1.17.1.9	ko:K00123,ko:K18332	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
TLS3_k127_2092958_7	1408433.JHXV01000017_gene1563	3.939e-67	246.0	COG3920@1|root,COG3920@2|Bacteria,4NEMC@976|Bacteroidetes,1HZHX@117743|Flavobacteriia,2PBKM@246874|Cryomorphaceae	976|Bacteroidetes	T	HWE histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_2
TLS3_k127_2092958_9	1122176.KB903532_gene2516	2.145e-52	185.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1INS2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S
TLS3_k127_2093818_4	391596.PBAL39_01757	3.507e-54	197.0	COG3132@1|root,COG3132@2|Bacteria,4NG7X@976|Bacteroidetes,1IRRC@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0502 family	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
TLS3_k127_2093818_3	755732.Fluta_2340	1.154e-87	323.0	COG3291@1|root,COG4935@1|root,COG5492@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,COG5492@2|Bacteria,4NDZQ@976|Bacteroidetes	976|Bacteroidetes	H	Gliding motility-associated C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,Ig_3
TLS3_k127_2093818_11	1317122.ATO12_13140	5.177e-14	87.0	COG1361@1|root,COG2911@1|root,COG4257@1|root,COG4932@1|root,COG4935@1|root,COG1361@2|Bacteria,COG2911@2|Bacteria,COG4257@2|Bacteria,COG4932@2|Bacteria,COG4935@2|Bacteria,4PKI1@976|Bacteroidetes,1IJ9R@117743|Flavobacteriia,2YGHB@290174|Aquimarina	976|Bacteroidetes	MOV	Domains in Na-Ca exchangers and integrin-beta4	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CUB,Calx-beta,DUF11,SdrD_B
TLS3_k127_2093818_0	755732.Fluta_3265	7.554e-135	443.0	COG3509@1|root,COG3509@2|Bacteria,4NHFS@976|Bacteroidetes,1I3VW@117743|Flavobacteriia,2PBGT@246874|Cryomorphaceae	976|Bacteroidetes	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase_phd
TLS3_k127_2093818_12	1034807.FBFL15_0915	1.761e-09	67.0	2A2GV@1|root,30QU7@2|Bacteria,4NYES@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2093818_7	926562.Oweho_1699	1.31e-38	147.0	COG4772@1|root,COG4772@2|Bacteria,4NE9I@976|Bacteroidetes,1HY4T@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_2093818_2	755732.Fluta_2735	2.647e-103	346.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_2093818_10	1223410.KN050846_gene694	7.241e-15	79.0	COG4818@1|root,COG4818@2|Bacteria,4NUVP@976|Bacteroidetes,1I44F@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2093818_5	926551.KB900713_gene2316	5.762e-52	197.0	2BYFB@1|root,2ZBSK@2|Bacteria,4NMAW@976|Bacteroidetes,1IJ5D@117743|Flavobacteriia,1ESRK@1016|Capnocytophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2093818_6	755732.Fluta_0696	4.376e-41	168.0	COG1835@1|root,COG1835@2|Bacteria,4PKKX@976|Bacteroidetes,1IJC6@117743|Flavobacteriia	976|Bacteroidetes	I	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
TLS3_k127_2093818_13	1262914.BN533_00493	4.653e-08	64.0	COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes	1239|Firmicutes	M	NlpC p60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,PG_binding_1
TLS3_k127_2093818_9	755732.Fluta_1672	1.442e-16	93.0	COG2885@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,4NKCW@976|Bacteroidetes,1HXSH@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM Outer membrane protein, OmpA MotB, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
TLS3_k127_2093818_8	1313421.JHBV01000042_gene3261	1.615e-30	136.0	COG2353@1|root,COG3210@1|root,COG2353@2|Bacteria,COG3210@2|Bacteria,4NIDX@976|Bacteroidetes	976|Bacteroidetes	U	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_2093818_1	1434325.AZQN01000003_gene2374	3.416e-106	367.0	COG0210@1|root,COG1112@1|root,COG0210@2|Bacteria,COG1112@2|Bacteria,4NEK7@976|Bacteroidetes,47MJ9@768503|Cytophagia	976|Bacteroidetes	L	PFAM Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
TLS3_k127_2105333_4	755732.Fluta_2853	1.598e-38	145.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,4NDY1@976|Bacteroidetes,1HXDN@117743|Flavobacteriia,2PBBW@246874|Cryomorphaceae	976|Bacteroidetes	O	Cytochrome C assembly protein	ccmC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
TLS3_k127_2105333_2	755732.Fluta_2855	2.241e-97	324.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1HWWB@117743|Flavobacteriia,2PAQS@246874|Cryomorphaceae	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
TLS3_k127_2105333_6	1443665.JACA01000001_gene2892	8.167e-23	103.0	COG0782@1|root,COG0782@2|Bacteria,4NQAD@976|Bacteroidetes,1I55E@117743|Flavobacteriia,2YJGF@290174|Aquimarina	976|Bacteroidetes	K	Transcription elongation factor	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB
TLS3_k127_2105333_3	755732.Fluta_2860	6.892e-67	241.0	COG0438@1|root,COG0438@2|Bacteria,4PI54@976|Bacteroidetes,1I2FR@117743|Flavobacteriia,2PB22@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_2105333_0	755732.Fluta_2862	3.423e-159	510.0	COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,1HXF8@117743|Flavobacteriia,2PA7V@246874|Cryomorphaceae	976|Bacteroidetes	E	Beta-eliminating lyase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
TLS3_k127_2105333_5	1121930.AQXG01000005_gene554	8.285e-32	130.0	COG4430@1|root,COG4430@2|Bacteria,4NW07@976|Bacteroidetes,1IZ0S@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
TLS3_k127_2105333_1	755732.Fluta_2864	3.647e-111	371.0	COG2304@1|root,COG2304@2|Bacteria,4NEGD@976|Bacteroidetes,1HY72@117743|Flavobacteriia,2PBM0@246874|Cryomorphaceae	976|Bacteroidetes	P	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
TLS3_k127_2128450_6	1121895.Q765_10755	1.695e-61	215.0	COG2197@1|root,COG2197@2|Bacteria,4NQSY@976|Bacteroidetes,1I3EM@117743|Flavobacteriia,2NWUY@237|Flavobacterium	976|Bacteroidetes	KT	LuxR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
TLS3_k127_2128450_4	1121895.Q765_10750	5.584e-74	253.0	2CB8S@1|root,30PE6@2|Bacteria,4NU1E@976|Bacteroidetes,1II6M@117743|Flavobacteriia,2P0B4@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
TLS3_k127_2128450_5	307480.IW16_13975	2.343e-72	247.0	COG0346@1|root,COG0346@2|Bacteria,4NNNG@976|Bacteroidetes,1I1XF@117743|Flavobacteriia,3ZS7I@59732|Chryseobacterium	976|Bacteroidetes	E	glyoxalase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
TLS3_k127_2128450_3	1286632.P278_20750	1.525e-82	287.0	COG0845@1|root,COG0845@2|Bacteria,4NITE@976|Bacteroidetes,1HZI0@117743|Flavobacteriia	976|Bacteroidetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,HlyD_D23
TLS3_k127_2128450_0	1237149.C900_04322	4.95e-176	560.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,47MB4@768503|Cytophagia	976|Bacteroidetes	M	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
TLS3_k127_2128450_1	1178825.ALIH01000006_gene1559	5.158e-104	342.0	COG1136@1|root,COG1136@2|Bacteria,4NFCG@976|Bacteroidetes,1HZKS@117743|Flavobacteriia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
TLS3_k127_2128450_2	755732.Fluta_2872	2.878e-86	294.0	COG3527@1|root,COG3527@2|Bacteria,4NKWJ@976|Bacteroidetes,1HX22@117743|Flavobacteriia	976|Bacteroidetes	Q	Alpha-acetolactate decarboxylase	alsD	-	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660	-	R02948	RC00812	ko00000,ko00001,ko01000	-	-	-	AAL_decarboxy
TLS3_k127_2131739_4	1408433.JHXV01000024_gene1458	4.543e-31	126.0	COG1629@1|root,COG1629@2|Bacteria,4PP5X@976|Bacteroidetes	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3
TLS3_k127_2131739_3	1317122.ATO12_01850	3.4e-54	192.0	COG0662@1|root,COG0662@2|Bacteria,4NS6V@976|Bacteroidetes,1I30K@117743|Flavobacteriia,2YJMG@290174|Aquimarina	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_2131739_5	545693.BMQ_2586	8.929e-21	101.0	COG1683@1|root,COG1683@2|Bacteria,1V700@1239|Firmicutes,4HJH0@91061|Bacilli,1ZGEW@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF523)	ybbK	-	-	-	-	-	-	-	-	-	-	-	DUF523
TLS3_k127_2131739_2	694427.Palpr_2733	1.492e-90	327.0	COG1629@1|root,COG4771@2|Bacteria,4NRFP@976|Bacteroidetes,2FTQ0@200643|Bacteroidia,22YFM@171551|Porphyromonadaceae	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3
TLS3_k127_2131739_1	1336803.PHEL49_2169	2.035e-202	647.0	COG2936@1|root,COG2936@2|Bacteria,4P0KE@976|Bacteroidetes	976|Bacteroidetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
TLS3_k127_2131739_0	755732.Fluta_1488	2.467e-232	732.0	COG4206@1|root,COG4206@2|Bacteria,4NIJS@976|Bacteroidetes	976|Bacteroidetes	H	COG4206 Outer membrane cobalamin receptor protein	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_2137815_3	755732.Fluta_2348	1.007e-08	62.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF4082,DUF4347,HemolysinCabind,SprB
TLS3_k127_2137815_1	1121897.AUGO01000008_gene2742	5.465e-87	302.0	COG2931@1|root,COG5295@1|root,COG2931@2|Bacteria,COG5295@2|Bacteria,4NF3S@976|Bacteroidetes,1I2TY@117743|Flavobacteriia,2NZZ4@237|Flavobacterium	976|Bacteroidetes	UW	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Peptidase_S74
TLS3_k127_2137815_2	1408433.JHXV01000002_gene280	1.262e-14	81.0	2AQPR@1|root,31FXA@2|Bacteria,4PJ02@976|Bacteroidetes,1ICSV@117743|Flavobacteriia,2PC13@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
TLS3_k127_2137815_0	755732.Fluta_3632	9.768e-227	707.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,1HX0N@117743|Flavobacteriia,2PA7C@246874|Cryomorphaceae	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
TLS3_k127_2180697_7	1267211.KI669560_gene1829	5.584e-15	83.0	COG2367@1|root,COG2367@2|Bacteria,4NH6K@976|Bacteroidetes,1INP4@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
TLS3_k127_2180697_1	388467.A19Y_3367	1.121e-102	350.0	COG0531@1|root,COG0531@2|Bacteria,1G2GM@1117|Cyanobacteria,1H9QG@1150|Oscillatoriales	1117|Cyanobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
TLS3_k127_2180697_3	313606.M23134_02910	6.464e-93	319.0	28J0S@1|root,2Z8XX@2|Bacteria,4NNYA@976|Bacteroidetes,47USS@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2180697_4	313606.M23134_04071	2.083e-57	213.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	COesterase,DUF2920,Hydrolase_4,Peptidase_S9
TLS3_k127_2180697_5	1121935.AQXX01000135_gene3763	1.566e-33	135.0	COG2148@1|root,COG2148@2|Bacteria	2|Bacteria	M	undecaprenyl-phosphate glucose phosphotransferase activity	epsL	-	-	ko:K19428	-	-	-	-	ko00000,ko01000	-	-	-	Bac_transf,CoA_binding_3
TLS3_k127_2180697_2	1396141.BATP01000005_gene5970	3.336e-94	320.0	COG0057@1|root,COG0057@2|Bacteria	2|Bacteria	G	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	-	-	1.2.1.12,1.2.1.59,1.4.1.16	ko:K00134,ko:K00150,ko:K03340	ko00010,ko00300,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00300,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00526,M00552	R01061,R01063,R02755	RC00006,RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	DapB_N,Gp_dh_C,Gp_dh_N
TLS3_k127_2180697_6	1117958.PE143B_0107900	5.448e-20	104.0	COG2885@1|root,COG3047@1|root,COG2885@2|Bacteria,COG3047@2|Bacteria,1R8DG@1224|Proteobacteria,1RP3K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the ompA family	oprF	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,OprF,TSP_3
TLS3_k127_2180697_0	984262.SGRA_2555	8.603e-114	394.0	COG3405@1|root,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_15,CHU_C
TLS3_k127_2182628_0	1307759.JOMJ01000004_gene2829	4.561e-121	402.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,42Q03@68525|delta/epsilon subdivisions,2WMFQ@28221|Deltaproteobacteria,2MBAU@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Transposase domain (DUF772)	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
TLS3_k127_2182628_1	1206730.BAGA01000081_gene821	8.352e-104	366.0	COG1201@1|root,COG1201@2|Bacteria,2I4TJ@201174|Actinobacteria,4G9YM@85025|Nocardiaceae	201174|Actinobacteria	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C
TLS3_k127_2202840_20	485917.Phep_0107	5.704e-15	75.0	COG1361@1|root,COG3405@1|root,COG4719@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3405@2|Bacteria,COG4719@2|Bacteria,COG4932@2|Bacteria,4NMB8@976|Bacteroidetes,1IQMS@117747|Sphingobacteriia	976|Bacteroidetes	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG,SdrD_B
TLS3_k127_2202840_6	755732.Fluta_2529	2.23e-122	406.0	COG0477@1|root,COG2814@2|Bacteria,4NFM7@976|Bacteroidetes,1HYPP@117743|Flavobacteriia,2PAJK@246874|Cryomorphaceae	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	tetA	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
TLS3_k127_2202840_18	1392490.JHZX01000001_gene3082	2.005e-25	109.0	2EI2Y@1|root,33BUE@2|Bacteria,4NZ4J@976|Bacteroidetes,1I5MM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2202840_17	1124780.ANNU01000023_gene3179	7.371e-43	163.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,47QFI@768503|Cytophagia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_2202840_24	1121887.AUDK01000004_gene289	0.0008608	51.0	COG3637@1|root,COG3637@2|Bacteria,4PKDR@976|Bacteroidetes,1IJ8F@117743|Flavobacteriia,2P0KR@237|Flavobacterium	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2202840_11	391587.KAOT1_13027	1.543e-66	232.0	COG0500@1|root,COG2226@2|Bacteria,4PGF8@976|Bacteroidetes,1IA5F@117743|Flavobacteriia	976|Bacteroidetes	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_2202840_10	1454007.JAUG01000090_gene710	3.562e-69	240.0	COG1357@1|root,COG1357@2|Bacteria,4NQ3B@976|Bacteroidetes,1ISGY@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
TLS3_k127_2202840_14	880071.Fleli_2317	5.083e-52	192.0	COG2856@1|root,COG2856@2|Bacteria,4NN24@976|Bacteroidetes,47QZG@768503|Cytophagia	976|Bacteroidetes	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2202840_12	643867.Ftrac_3272	2.418e-62	217.0	COG0484@1|root,COG0484@2|Bacteria,4NME2@976|Bacteroidetes,47RGP@768503|Cytophagia	976|Bacteroidetes	O	KTSC domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,KTSC
TLS3_k127_2202840_0	760192.Halhy_5073	0.0	1522.0	COG0745@1|root,COG1352@1|root,COG2201@1|root,COG5002@1|root,COG0745@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,4PKNJ@976|Bacteroidetes,1IPG2@117747|Sphingobacteriia	976|Bacteroidetes	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_2202840_5	755732.Fluta_0635	6.849e-130	431.0	2ENP2@1|root,33GAE@2|Bacteria,4NZIT@976|Bacteroidetes,1I8VS@117743|Flavobacteriia,2PB29@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2202840_7	1408433.JHXV01000005_gene2236	1.924e-121	398.0	COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,1HXBB@117743|Flavobacteriia,2PADX@246874|Cryomorphaceae	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
TLS3_k127_2202840_15	755732.Fluta_0643	1.552e-50	183.0	COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,1I20S@117743|Flavobacteriia,2PB0D@246874|Cryomorphaceae	976|Bacteroidetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
TLS3_k127_2202840_3	755732.Fluta_0644	8.085e-139	446.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1HYPM@117743|Flavobacteriia,2PABU@246874|Cryomorphaceae	976|Bacteroidetes	D	PFAM Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
TLS3_k127_2202840_16	755732.Fluta_2470	6.518e-48	178.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1IG89@117743|Flavobacteriia,2PBUT@246874|Cryomorphaceae	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_2202840_22	272134.KB731324_gene4251	1.649e-07	61.0	COG0457@1|root,COG0457@2|Bacteria,1G0IA@1117|Cyanobacteria,1H81Y@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6
TLS3_k127_2202840_2	755732.Fluta_0646	1.223e-243	762.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,1HXRF@117743|Flavobacteriia,2PAK2@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
TLS3_k127_2202840_9	755732.Fluta_3621	1.291e-99	329.0	COG3155@1|root,COG3155@2|Bacteria,4NMIE@976|Bacteroidetes,1I8RR@117743|Flavobacteriia,2PBG8@246874|Cryomorphaceae	976|Bacteroidetes	Q	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
TLS3_k127_2202840_1	755732.Fluta_3624	2.065e-290	897.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1HX6C@117743|Flavobacteriia,2PA7A@246874|Cryomorphaceae	976|Bacteroidetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
TLS3_k127_2202840_4	755732.Fluta_0007	2.1e-134	434.0	COG1363@1|root,COG1363@2|Bacteria,4NH34@976|Bacteroidetes,1ICPM@117743|Flavobacteriia,2PBIU@246874|Cryomorphaceae	976|Bacteroidetes	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
TLS3_k127_2202840_13	755732.Fluta_0006	5.038e-53	193.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,1HY82@117743|Flavobacteriia,2PAZR@246874|Cryomorphaceae	976|Bacteroidetes	S	Uncharacterized protein family UPF0029	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
TLS3_k127_2202840_8	1408433.JHXV01000041_gene3580	3.217e-107	352.0	COG0330@1|root,COG0330@2|Bacteria,4NEP5@976|Bacteroidetes,1HWKG@117743|Flavobacteriia,2PC2X@246874|Cryomorphaceae	976|Bacteroidetes	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
TLS3_k127_2203782_15	1121898.Q766_16355	6.197e-17	85.0	2E134@1|root,314GP@2|Bacteria,4NR5I@976|Bacteroidetes,1I64S@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2203782_9	1173028.ANKO01000250_gene2402	6.112e-70	245.0	COG0500@1|root,COG0500@2|Bacteria,1GQKE@1117|Cyanobacteria,1HI8E@1150|Oscillatoriales	1117|Cyanobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_2203782_6	1408433.JHXV01000014_gene3608	5.202e-94	316.0	28K7U@1|root,2Z9VT@2|Bacteria,4NIK4@976|Bacteroidetes,1I4P6@117743|Flavobacteriia,2PBJX@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2203782_1	1173028.ANKO01000250_gene2401	2.494e-166	529.0	COG0399@1|root,COG0399@2|Bacteria,1G0XH@1117|Cyanobacteria,1H93R@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_2203782_0	1313301.AUGC01000009_gene1059	7.237e-184	580.0	COG1089@1|root,COG1089@2|Bacteria,4NEB6@976|Bacteroidetes	976|Bacteroidetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
TLS3_k127_2203782_11	1357399.HMPREF2087_01777	3.833e-51	185.0	2BWTW@1|root,315N7@2|Bacteria,1RABY@1224|Proteobacteria,42T71@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2203782_14	865937.Gilli_1065	3.38e-24	114.0	COG1215@1|root,COG1215@2|Bacteria,4NNGJ@976|Bacteroidetes,1I23Y@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_2203782_13	1048983.EL17_11170	4.693e-25	119.0	2DMHZ@1|root,32RNI@2|Bacteria,4NTBA@976|Bacteroidetes,47RKI@768503|Cytophagia	976|Bacteroidetes	S	4-alpha-L-fucosyltransferase glycosyl transferase group 56	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_56
TLS3_k127_2203782_8	558152.IQ37_00305	2.705e-78	269.0	COG0223@1|root,COG0223@2|Bacteria,4NPF8@976|Bacteroidetes,1IJYZ@117743|Flavobacteriia	976|Bacteroidetes	J	Formyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_N
TLS3_k127_2203782_3	1144313.PMI10_00330	8.467e-145	467.0	COG0399@1|root,COG0399@2|Bacteria,4NGI4@976|Bacteroidetes,1HYZI@117743|Flavobacteriia,2NSCH@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	vioA	-	2.6.1.33	ko:K20429	-	-	R02773	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_2203782_2	1121899.Q764_08505	6.613e-146	482.0	COG1134@1|root,COG1134@2|Bacteria,4NEDM@976|Bacteroidetes,1HXJV@117743|Flavobacteriia,2NT6Z@237|Flavobacterium	976|Bacteroidetes	GM	ABC-type polysaccharide polyol phosphate transport system, ATPase component	rfbB	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
TLS3_k127_2203782_5	760192.Halhy_2850	6.258e-103	342.0	COG1682@1|root,COG1682@2|Bacteria,4NF36@976|Bacteroidetes,1IRBJ@117747|Sphingobacteriia	976|Bacteroidetes	GM	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
TLS3_k127_2203782_7	755732.Fluta_0715	7.938e-79	281.0	28ICP@1|root,2Z8EZ@2|Bacteria,4NKKI@976|Bacteroidetes,1IMS0@117743|Flavobacteriia,2PBUC@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2203782_10	216432.CA2559_08411	3.478e-51	190.0	COG1576@1|root,COG1576@2|Bacteria,4NMFP@976|Bacteroidetes,1I1AB@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
TLS3_k127_2203782_4	755732.Fluta_0712	1.233e-115	379.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,1HXPC@117743|Flavobacteriia,2PAAY@246874|Cryomorphaceae	976|Bacteroidetes	H	PFAM Quinolinate phosphoribosyl transferase, C-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
TLS3_k127_2204696_19	925409.KI911562_gene1729	2.59e-08	65.0	2EHJH@1|root,33BBD@2|Bacteria,4NXG2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2204696_13	755732.Fluta_1652	2.412e-81	281.0	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,1HZ1Y@117743|Flavobacteriia,2PATB@246874|Cryomorphaceae	976|Bacteroidetes	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
TLS3_k127_2204696_9	755732.Fluta_1653	2.356e-113	374.0	COG2222@1|root,COG2222@2|Bacteria,4NIX0@976|Bacteroidetes,1I8JM@117743|Flavobacteriia,2PANV@246874|Cryomorphaceae	976|Bacteroidetes	G	PFAM Bacterial phospho-glucose isomerase C-terminal region	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
TLS3_k127_2204696_11	755732.Fluta_1980	4.45e-102	336.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,1HXZT@117743|Flavobacteriia,2PAP5@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
TLS3_k127_2204696_7	755732.Fluta_1979	5.446e-141	458.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,1HY9H@117743|Flavobacteriia,2PASK@246874|Cryomorphaceae	976|Bacteroidetes	V	Beta-lactamase	nylB	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_2204696_15	755732.Fluta_1978	7.899e-54	192.0	2AGNU@1|root,316WB@2|Bacteria,4NSNZ@976|Bacteroidetes,1I2U3@117743|Flavobacteriia,2PB8B@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2204696_14	755732.Fluta_0931	3.386e-57	206.0	2A99R@1|root,30YEM@2|Bacteria,4PC7U@976|Bacteroidetes,1ICSR@117743|Flavobacteriia,2PC0I@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2204696_5	755732.Fluta_0917	2.146e-184	581.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,1HWR0@117743|Flavobacteriia,2PA6F@246874|Cryomorphaceae	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
TLS3_k127_2204696_18	755732.Fluta_0916	9.178e-24	102.0	COG0694@1|root,COG0694@2|Bacteria,4NSHJ@976|Bacteroidetes,1I3YF@117743|Flavobacteriia,2PB7U@246874|Cryomorphaceae	976|Bacteroidetes	O	NifU-like domain	nfuA	-	-	-	-	-	-	-	-	-	-	-	NifU
TLS3_k127_2204696_17	1121373.KB903635_gene849	1.541e-32	138.0	2EBH5@1|root,335HP@2|Bacteria,4NW0F@976|Bacteroidetes,47VF8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2204696_10	755732.Fluta_0914	1.754e-109	356.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,1HX6F@117743|Flavobacteriia,2PAN7@246874|Cryomorphaceae	976|Bacteroidetes	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
TLS3_k127_2204696_6	755732.Fluta_0912	4.869e-146	475.0	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,1HXD8@117743|Flavobacteriia,2PBCW@246874|Cryomorphaceae	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_2204696_0	755732.Fluta_0911	5.806e-293	932.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1HX85@117743|Flavobacteriia,2PBGY@246874|Cryomorphaceae	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_2204696_16	755732.Fluta_0910	2.392e-45	168.0	29AZZ@1|root,2ZXYX@2|Bacteria,4NP6M@976|Bacteroidetes,1IEC8@117743|Flavobacteriia,2PB6A@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2204696_20	404589.Anae109_2405	4.384e-06	53.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
TLS3_k127_2204696_2	755732.Fluta_0908	1.432e-194	613.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,1HXBZ@117743|Flavobacteriia,2PAEV@246874|Cryomorphaceae	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
TLS3_k127_2204696_4	755732.Fluta_2008	2.278e-188	614.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_2204696_1	755732.Fluta_2007	4.227e-238	742.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,1HX16@117743|Flavobacteriia,2PABV@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_2204696_3	755732.Fluta_1149	2.225e-192	626.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,1HWKS@117743|Flavobacteriia,2PADG@246874|Cryomorphaceae	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
TLS3_k127_2204696_12	755732.Fluta_1148	1.905e-92	306.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,1HY1G@117743|Flavobacteriia,2PB1J@246874|Cryomorphaceae	976|Bacteroidetes	F	Thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
TLS3_k127_2204696_8	755732.Fluta_1146	1.198e-130	430.0	COG2234@1|root,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1HXXH@117743|Flavobacteriia,2PBDE@246874|Cryomorphaceae	976|Bacteroidetes	O	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
TLS3_k127_2221974_2	1313421.JHBV01000042_gene3227	4.543e-47	176.0	COG2324@1|root,COG2324@2|Bacteria,4NQR7@976|Bacteroidetes	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
TLS3_k127_2221974_0	1313421.JHBV01000042_gene3226	4.897e-133	441.0	COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes,1IR1U@117747|Sphingobacteriia	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
TLS3_k127_2221974_1	1313421.JHBV01000042_gene3225	1.649e-75	258.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,1IP80@117747|Sphingobacteriia	976|Bacteroidetes	I	Squalene phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
TLS3_k127_2226199_7	755732.Fluta_1629	9.097e-95	314.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	srrB	-	-	-	-	-	-	-	-	-	-	-	CBS,HAMP,SpoIIE,dCache_1
TLS3_k127_2226199_12	868131.MSWAN_1308	4.851e-40	164.0	COG0642@1|root,COG3920@1|root,arCOG02327@2157|Archaea,arCOG02335@2157|Archaea	2157|Archaea	T	PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	BAT,GAF,GAF_2,HATPase_c,HTH_10,HisKA,HisKA_2,HisKA_7TM,PAS,PAS_4,PAS_8,PAS_9,Response_reg
TLS3_k127_2226199_4	755732.Fluta_0927	9.241e-109	359.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,1HXFX@117743|Flavobacteriia,2PB1W@246874|Cryomorphaceae	976|Bacteroidetes	D	FtsX-like permease family	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
TLS3_k127_2226199_14	1408433.JHXV01000014_gene3685	1.148e-16	83.0	2E6VD@1|root,331EZ@2|Bacteria,4NUSW@976|Bacteroidetes,1I3VV@117743|Flavobacteriia,2PB8V@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF3098)	fjo13	-	-	-	-	-	-	-	-	-	-	-	DUF3098
TLS3_k127_2226199_5	1408433.JHXV01000014_gene3684	2.553e-107	353.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,1HWSY@117743|Flavobacteriia,2PB6H@246874|Cryomorphaceae	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
TLS3_k127_2226199_6	755732.Fluta_0924	8.017e-96	318.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,1HXCG@117743|Flavobacteriia,2PAR9@246874|Cryomorphaceae	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
TLS3_k127_2226199_0	755732.Fluta_0923	3.985e-199	624.0	COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,1HYMK@117743|Flavobacteriia,2PA7J@246874|Cryomorphaceae	976|Bacteroidetes	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
TLS3_k127_2226199_3	755732.Fluta_1921	4.296e-112	370.0	COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes,1HXXM@117743|Flavobacteriia,2PAS3@246874|Cryomorphaceae	976|Bacteroidetes	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
TLS3_k127_2226199_8	755732.Fluta_1920	1.815e-92	316.0	COG1845@1|root,COG1845@2|Bacteria,4NFA7@976|Bacteroidetes,1I1D8@117743|Flavobacteriia,2PB9Z@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Cytochrome c oxidase, subunit III	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
TLS3_k127_2226199_2	755732.Fluta_1919	2.424e-157	502.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,1HWXP@117743|Flavobacteriia,2PAN3@246874|Cryomorphaceae	976|Bacteroidetes	C	Heme copper-type cytochrome quinol oxidase subunit 3	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
TLS3_k127_2226199_13	755732.Fluta_1918	8.392e-39	148.0	COG5605@1|root,COG5605@2|Bacteria,4P9DD@976|Bacteroidetes,1IC4B@117743|Flavobacteriia,2PB81@246874|Cryomorphaceae	976|Bacteroidetes	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
TLS3_k127_2226199_10	755732.Fluta_1917	2.046e-71	247.0	COG1999@1|root,COG1999@2|Bacteria,4PJEN@976|Bacteroidetes,1ICTB@117743|Flavobacteriia,2PC3D@246874|Cryomorphaceae	976|Bacteroidetes	S	signal sequence binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2226199_9	755732.Fluta_1916	2.494e-73	253.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1I3NA@117743|Flavobacteriia,2PB1N@246874|Cryomorphaceae	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
TLS3_k127_2226199_11	755732.Fluta_1915	1.092e-55	199.0	COG2322@1|root,COG2322@2|Bacteria,4NM5N@976|Bacteroidetes,1I16X@117743|Flavobacteriia,2PB26@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF420)	yozB	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
TLS3_k127_2226199_1	984262.SGRA_2830	3.105e-159	528.0	COG0265@1|root,COG0265@2|Bacteria,4PKT1@976|Bacteroidetes,1IW78@117747|Sphingobacteriia	976|Bacteroidetes	O	Trypsin-like peptidase domain	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
TLS3_k127_2234575_0	755732.Fluta_2685	1.881e-114	378.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
TLS3_k127_2234575_2	760154.Sulba_0501	3.889e-19	88.0	COG2501@1|root,COG2501@2|Bacteria,1PFA5@1224|Proteobacteria,42XJ3@68525|delta/epsilon subdivisions,2YS84@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	S4 domain	-	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
TLS3_k127_2234575_1	755732.Fluta_2015	9.811e-74	254.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,1HWNS@117743|Flavobacteriia,2PA76@246874|Cryomorphaceae	976|Bacteroidetes	E	TIGRFAM LAO AO transport system ATPase	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
TLS3_k127_22539_3	1288963.ADIS_1416	3.349e-53	192.0	COG1652@1|root,COG1652@2|Bacteria,4NJV3@976|Bacteroidetes,47R3Z@768503|Cytophagia	976|Bacteroidetes	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_22539_4	398720.MED217_08625	2.205e-06	50.0	2EQ7Q@1|root,33HTY@2|Bacteria,4NXT8@976|Bacteroidetes,1I6T1@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_22539_2	1229487.AMYW01000027_gene2802	2.97e-71	243.0	2DMQT@1|root,32T2H@2|Bacteria,4NN19@976|Bacteroidetes,1I2XV@117743|Flavobacteriia,2NUY9@237|Flavobacterium	976|Bacteroidetes	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
TLS3_k127_22539_1	1202532.FF52_05300	1.258e-75	255.0	2DB76@1|root,2Z7JZ@2|Bacteria,4NQDC@976|Bacteroidetes,1I2ER@117743|Flavobacteriia,2NSQE@237|Flavobacterium	976|Bacteroidetes	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
TLS3_k127_22539_0	926556.Echvi_3597	1.41e-172	557.0	COG3497@1|root,COG3497@2|Bacteria,4NEKK@976|Bacteroidetes,47KYE@768503|Cytophagia	976|Bacteroidetes	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
TLS3_k127_2265140_5	743722.Sph21_5043	6.859e-26	118.0	COG4313@1|root,COG4313@2|Bacteria,4NIIB@976|Bacteroidetes,1IPT3@117747|Sphingobacteriia	976|Bacteroidetes	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
TLS3_k127_2265140_3	755732.Fluta_3177	1.79e-70	248.0	2DBUB@1|root,2ZB53@2|Bacteria,4NMWS@976|Bacteroidetes,1IGD0@117743|Flavobacteriia,2PBPS@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2265140_1	755732.Fluta_3176	1.478e-117	387.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1HXUF@117743|Flavobacteriia,2PBCS@246874|Cryomorphaceae	976|Bacteroidetes	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
TLS3_k127_2265140_4	525373.HMPREF0766_11689	4.66e-58	203.0	COG4319@1|root,COG4319@2|Bacteria,4NQ7F@976|Bacteroidetes,1IUKA@117747|Sphingobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
TLS3_k127_2265140_2	930166.CD58_14955	5.443e-84	317.0	COG1196@1|root,COG1196@2|Bacteria,1NXI2@1224|Proteobacteria,1SVUW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2265140_0	468059.AUHA01000003_gene1830	2.716e-154	492.0	COG2130@1|root,COG2130@2|Bacteria,4NGHX@976|Bacteroidetes,1IPTJ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Zinc-binding dehydrogenase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
TLS3_k127_2271334_5	398720.MED217_07986	6.886e-22	101.0	COG1670@1|root,COG1670@2|Bacteria,4NQ8K@976|Bacteroidetes,1I27H@117743|Flavobacteriia,2XJ8V@283735|Leeuwenhoekiella	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	speG	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
TLS3_k127_2271334_4	755732.Fluta_3410	1.914e-90	309.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,1HWPX@117743|Flavobacteriia,2PARF@246874|Cryomorphaceae	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
TLS3_k127_2271334_2	755732.Fluta_3411	4.058e-134	434.0	COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,1HXFB@117743|Flavobacteriia,2PB5N@246874|Cryomorphaceae	976|Bacteroidetes	E	Asparaginase	aspG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
TLS3_k127_2271334_0	755732.Fluta_3412	1.427e-273	864.0	COG3250@1|root,COG3250@2|Bacteria,4NE7H@976|Bacteroidetes,1HX95@117743|Flavobacteriia,2PBFX@246874|Cryomorphaceae	976|Bacteroidetes	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
TLS3_k127_2271334_1	755732.Fluta_0010	1.633e-238	758.0	COG0296@1|root,COG2957@1|root,COG0296@2|Bacteria,COG2957@2|Bacteria,4NJ5R@976|Bacteroidetes,1I7K9@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase family C25, C terminal ig-like domain	-	GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.22.37	ko:K08589	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_C25,Peptidase_C25_C,Propeptide_C25
TLS3_k127_2271334_3	1408433.JHXV01000034_gene8	2.516e-124	419.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
TLS3_k127_2286399_2	1408433.JHXV01000019_gene1917	2.476e-46	177.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1HYIP@117743|Flavobacteriia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2286399_1	755732.Fluta_1079	7.966e-159	506.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,1HWNB@117743|Flavobacteriia,2PA5U@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
TLS3_k127_2286399_0	1408433.JHXV01000005_gene2536	3.713e-178	566.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1I7RH@117743|Flavobacteriia,2PAGH@246874|Cryomorphaceae	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
TLS3_k127_2286399_3	1008457.BAEX01000005_gene952	7.156e-10	62.0	2ET6A@1|root,33KQC@2|Bacteria,4NYA0@976|Bacteroidetes,1IBA5@117743|Flavobacteriia,47J63@76831|Myroides	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2291340_14	755732.Fluta_2731	2.256e-28	121.0	2CA1R@1|root,32FVT@2|Bacteria,4PBTZ@976|Bacteroidetes,1I9V5@117743|Flavobacteriia,2PBA8@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
TLS3_k127_2291340_0	755732.Fluta_2730	0.0	1072.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1HWZJ@117743|Flavobacteriia,2PA6U@246874|Cryomorphaceae	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
TLS3_k127_2291340_2	755732.Fluta_2729	2.057e-149	476.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1HWSN@117743|Flavobacteriia,2PBB2@246874|Cryomorphaceae	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS3_k127_2291340_9	755732.Fluta_2727	2.917e-50	182.0	COG0394@1|root,COG0394@2|Bacteria,4NNQZ@976|Bacteroidetes,1I1Z5@117743|Flavobacteriia,2PAVY@246874|Cryomorphaceae	976|Bacteroidetes	T	PFAM Low molecular weight phosphotyrosine protein phosphatase	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
TLS3_k127_2291340_5	755732.Fluta_2726	2.996e-90	304.0	COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,1HXGW@117743|Flavobacteriia,2PAVQ@246874|Cryomorphaceae	976|Bacteroidetes	H	Methyltransferase	-	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
TLS3_k127_2291340_6	755732.Fluta_2724	3.959e-85	289.0	COG1076@1|root,COG1076@2|Bacteria,4NF1B@976|Bacteroidetes,1HYUI@117743|Flavobacteriia,2PBZR@246874|Cryomorphaceae	976|Bacteroidetes	O	Tellurite resistance protein TerB	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
TLS3_k127_2291340_1	755732.Fluta_2723	2.879e-315	974.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,1HX8U@117743|Flavobacteriia,2PAJ8@246874|Cryomorphaceae	976|Bacteroidetes	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
TLS3_k127_2291340_7	755732.Fluta_0667	6.793e-83	294.0	28ZU6@1|root,2ZMIV@2|Bacteria,4P83G@976|Bacteroidetes,1IMR8@117743|Flavobacteriia,2PBNF@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2291340_3	755732.Fluta_0666	2.916e-101	335.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,1HY5P@117743|Flavobacteriia,2PAN0@246874|Cryomorphaceae	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_2291340_11	755732.Fluta_2668	1.627e-37	149.0	COG1051@1|root,COG1051@2|Bacteria,4NS9I@976|Bacteroidetes,1HZFF@117743|Flavobacteriia,2PB59@246874|Cryomorphaceae	976|Bacteroidetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_2291340_4	755732.Fluta_2667	5.249e-100	330.0	COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,1HXXU@117743|Flavobacteriia,2PANI@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10,4.1.1.23	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
TLS3_k127_2291340_12	755732.Fluta_2666	9.584e-35	138.0	COG3427@1|root,COG3427@2|Bacteria,4PHJK@976|Bacteroidetes,1IGIK@117743|Flavobacteriia,2PB7C@246874|Cryomorphaceae	976|Bacteroidetes	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2291340_10	471854.Dfer_5042	1.666e-43	168.0	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,47MUP@768503|Cytophagia	976|Bacteroidetes	H	PFAM Biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
TLS3_k127_2291340_8	755732.Fluta_2664	6.759e-56	197.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,1I1ZH@117743|Flavobacteriia,2PB3B@246874|Cryomorphaceae	976|Bacteroidetes	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
TLS3_k127_2291340_13	755732.Fluta_2663	5.669e-31	128.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1HXSC@117743|Flavobacteriia,2PA4Q@246874|Cryomorphaceae	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
TLS3_k127_2300331_3	1469557.JSWF01000012_gene1174	1.73e-27	114.0	COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,1I3XI@117743|Flavobacteriia	976|Bacteroidetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
TLS3_k127_2300331_0	755732.Fluta_3559	4.399e-134	429.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,1HXDZ@117743|Flavobacteriia,2PA7F@246874|Cryomorphaceae	976|Bacteroidetes	IQ	PFAM short chain dehydrogenase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_2300331_2	1408433.JHXV01000017_gene1629	1.275e-27	119.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,1I942@117743|Flavobacteriia,2PBH5@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran
TLS3_k127_2306687_4	1408433.JHXV01000008_gene166	6.301e-94	309.0	COG0208@1|root,COG0208@2|Bacteria,4NG18@976|Bacteroidetes,1HXA5@117743|Flavobacteriia,2PAD3@246874|Cryomorphaceae	976|Bacteroidetes	F	Ribonucleotide reductase, small chain	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
TLS3_k127_2306687_0	755732.Fluta_1807	0.0	1452.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXHB@117743|Flavobacteriia,2PA5B@246874|Cryomorphaceae	976|Bacteroidetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
TLS3_k127_2306687_2	926562.Oweho_0256	3.13e-171	544.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1HX6Q@117743|Flavobacteriia,2PAJS@246874|Cryomorphaceae	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
TLS3_k127_2306687_8	1178825.ALIH01000010_gene429	1.071e-32	128.0	COG4807@1|root,COG4807@2|Bacteria,4NSYM@976|Bacteroidetes,1I3ZP@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1456
TLS3_k127_2306687_3	1341181.FLJC2902T_15050	2.241e-95	317.0	COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,1HYKM@117743|Flavobacteriia,2NTPY@237|Flavobacterium	976|Bacteroidetes	FJ	tRNA hydroxylase	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
TLS3_k127_2306687_6	755732.Fluta_1972	1.995e-72	266.0	COG1807@1|root,COG1807@2|Bacteria,4PB0R@976|Bacteroidetes,1I8NW@117743|Flavobacteriia,2PBV3@246874|Cryomorphaceae	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2306687_5	1408433.JHXV01000040_gene1525	1.18e-83	284.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,1HXTT@117743|Flavobacteriia,2PATM@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
TLS3_k127_2306687_7	755732.Fluta_1865	4.797e-46	171.0	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,1I2U1@117743|Flavobacteriia,2PB45@246874|Cryomorphaceae	976|Bacteroidetes	J	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
TLS3_k127_2306687_1	755732.Fluta_1866	4.867e-236	733.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,1HY37@117743|Flavobacteriia,2PAGI@246874|Cryomorphaceae	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
TLS3_k127_2306687_9	755732.Fluta_1867	6.389e-31	128.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,1HYR7@117743|Flavobacteriia,2PA7N@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
TLS3_k127_2312218_3	755732.Fluta_3512	3.101e-38	146.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1HXFD@117743|Flavobacteriia,2PBBE@246874|Cryomorphaceae	976|Bacteroidetes	O	Subtilase family	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_2312218_2	755732.Fluta_3511	8.827e-46	169.0	COG4319@1|root,COG4319@2|Bacteria,4NNSF@976|Bacteroidetes,1I234@117743|Flavobacteriia,2PBYQ@246874|Cryomorphaceae	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
TLS3_k127_2312218_4	755732.Fluta_0630	2.367e-36	143.0	29Y6K@1|root,30K03@2|Bacteria,4PGXF@976|Bacteroidetes,1IEKQ@117743|Flavobacteriia,2PBXX@246874|Cryomorphaceae	976|Bacteroidetes	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
TLS3_k127_2312218_0	755732.Fluta_3495	1.744e-111	363.0	COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,1HXUY@117743|Flavobacteriia,2PAIW@246874|Cryomorphaceae	976|Bacteroidetes	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
TLS3_k127_2312218_1	643867.Ftrac_1191	4.913e-46	176.0	COG2208@1|root,COG2208@2|Bacteria,4NKKK@976|Bacteroidetes,47MR0@768503|Cytophagia	976|Bacteroidetes	KT	Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,SpoIIE
TLS3_k127_2316636_6	1484460.JSWG01000003_gene795	1.596e-26	109.0	2DMRQ@1|root,32T84@2|Bacteria,4NU8C@976|Bacteroidetes,1I2RC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2316636_3	1227739.Hsw_3507	1.088e-51	201.0	2EF95@1|root,33921@2|Bacteria,4NXAE@976|Bacteroidetes,47T74@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2316636_1	755732.Fluta_3278	3.208e-136	438.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,1HY41@117743|Flavobacteriia,2PAMG@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
TLS3_k127_2316636_0	755732.Fluta_3279	2.286e-240	750.0	COG1249@1|root,COG1249@2|Bacteria,4NJ2P@976|Bacteroidetes,1IGB0@117743|Flavobacteriia,2PBK6@246874|Cryomorphaceae	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_2316636_4	755732.Fluta_3280	2.718e-50	189.0	COG0727@1|root,COG0727@2|Bacteria,4NJH9@976|Bacteroidetes,1HZQ3@117743|Flavobacteriia,2PAWU@246874|Cryomorphaceae	976|Bacteroidetes	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
TLS3_k127_2316636_2	755732.Fluta_3281	3.355e-65	238.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2PBEH@246874|Cryomorphaceae	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gly_rich,HYR,Laminin_G_3,PKD,SprB,VCBS
TLS3_k127_2317160_2	1121285.AUFK01000016_gene3505	1.031e-08	68.0	2DPZ9@1|root,3341K@2|Bacteria,4P250@976|Bacteroidetes,1I84S@117743|Flavobacteriia,3ZP7T@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2317160_0	755732.Fluta_1672	6.155e-26	119.0	COG2885@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,4NKCW@976|Bacteroidetes,1HXSH@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM Outer membrane protein, OmpA MotB, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
TLS3_k127_2317160_3	1123278.KB893566_gene2197	3.23e-05	54.0	2ECA3@1|root,32QV4@2|Bacteria,4NRYD@976|Bacteroidetes,47QR1@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2317160_1	1008457.BAEX01000005_gene952	2.467e-12	70.0	2ET6A@1|root,33KQC@2|Bacteria,4NYA0@976|Bacteroidetes,1IBA5@117743|Flavobacteriia,47J63@76831|Myroides	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2317427_4	1392498.JQLH01000001_gene1659	1.949e-34	134.0	COG3608@1|root,COG3608@2|Bacteria,4NE8S@976|Bacteroidetes,1HXAJ@117743|Flavobacteriia,2PH9N@252356|Maribacter	976|Bacteroidetes	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
TLS3_k127_2317427_3	1220534.B655_1977	1.822e-44	171.0	COG2203@1|root,arCOG02361@2157|Archaea	2157|Archaea	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg
TLS3_k127_2317427_6	984262.SGRA_0140	8.401e-13	73.0	2DS7J@1|root,33EW7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
TLS3_k127_2317427_2	1469557.JSWF01000022_gene511	7.026e-57	202.0	COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,1I30V@117743|Flavobacteriia	976|Bacteroidetes	S	Damage-inducible protein DinB	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_2317427_0	1408433.JHXV01000005_gene2401	3.819e-80	272.0	COG2197@1|root,COG2197@2|Bacteria,4NP21@976|Bacteroidetes,1IG33@117743|Flavobacteriia,2PBN0@246874|Cryomorphaceae	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_2317427_1	1408433.JHXV01000005_gene2402	1.38e-72	252.0	COG4585@1|root,COG4585@2|Bacteria,4NNE1@976|Bacteroidetes,1I1SW@117743|Flavobacteriia,2PBQW@246874|Cryomorphaceae	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TLS3_k127_2322518_0	1150600.ADIARSV_2341	4.995e-23	108.0	COG0464@1|root,COG0464@2|Bacteria,4NFWG@976|Bacteroidetes,1IR7U@117747|Sphingobacteriia	976|Bacteroidetes	O	AAA ATPase central domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA
TLS3_k127_2322518_1	1120965.AUBV01000004_gene890	4.281e-06	61.0	COG4942@1|root,COG4942@2|Bacteria,4NTB7@976|Bacteroidetes,47R8P@768503|Cytophagia	976|Bacteroidetes	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2337718_1	1408433.JHXV01000020_gene3505	9.792e-147	480.0	COG4774@1|root,COG4774@2|Bacteria,4PKNF@976|Bacteroidetes,1IKD6@117743|Flavobacteriia,2PAIX@246874|Cryomorphaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
TLS3_k127_2337718_0	926562.Oweho_0375	6.415e-151	491.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1HYNS@117743|Flavobacteriia,2PAX1@246874|Cryomorphaceae	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
TLS3_k127_2337718_2	28532.XP_010529207.1	0.0006313	48.0	2C0P6@1|root,2S2MZ@2759|Eukaryota,37VSQ@33090|Viridiplantae,3GJUH@35493|Streptophyta,3HUZK@3699|Brassicales	35493|Streptophyta	S	Rho termination factor, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
TLS3_k127_2359544_5	755732.Fluta_2019	4.976e-105	363.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4P1A1@976|Bacteroidetes	2|Bacteria	E	Pkd domain containing protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,HYR,MAM,PKD,Peptidase_M43,Peptidase_S8,SprB,fn3
TLS3_k127_2359544_11	319236.JCM19294_911	3.525e-12	79.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,4PHVK@976|Bacteroidetes,1IDN4@117743|Flavobacteriia,3HJ5A@363408|Nonlabens	976|Bacteroidetes	O	Fibronectin type III domain	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	MAM,fn3
TLS3_k127_2359544_6	755732.Fluta_2020	5.665e-105	346.0	COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,1HY8Z@117743|Flavobacteriia,2PA73@246874|Cryomorphaceae	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_2359544_1	755732.Fluta_2021	7.535e-284	894.0	COG3291@1|root,COG3291@2|Bacteria,4PFQY@976|Bacteroidetes,1ICPB@117743|Flavobacteriia,2PBH6@246874|Cryomorphaceae	976|Bacteroidetes	S	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta
TLS3_k127_2359544_9	411477.PARMER_04118	9.389e-42	165.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,2FMIQ@200643|Bacteroidia,22XKT@171551|Porphyromonadaceae	976|Bacteroidetes	M	Peptidase family M23	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_2359544_3	755732.Fluta_2022	2.215e-220	700.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1HWWR@117743|Flavobacteriia,2PAGR@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase and permease	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS3_k127_2359544_8	755732.Fluta_2023	5.868e-42	157.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,1I2VE@117743|Flavobacteriia,2PB4Y@246874|Cryomorphaceae	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
TLS3_k127_2359544_4	755732.Fluta_2024	3.647e-120	398.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,1HX67@117743|Flavobacteriia,2PAVH@246874|Cryomorphaceae	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
TLS3_k127_2359544_0	755732.Fluta_1114	2.584e-292	900.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1HWM2@117743|Flavobacteriia,2PAC3@246874|Cryomorphaceae	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
TLS3_k127_2359544_10	755732.Fluta_1115	2.963e-30	123.0	COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,1I5R2@117743|Flavobacteriia,2PB9U@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM ATP synthase, Delta Epsilon chain, beta-sandwich domain	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
TLS3_k127_2359544_7	755732.Fluta_1116	2.047e-101	335.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1HXRP@117743|Flavobacteriia,2PANN@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
TLS3_k127_2359544_2	755732.Fluta_1117	7.632e-252	789.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1HWVA@117743|Flavobacteriia,2PAC5@246874|Cryomorphaceae	976|Bacteroidetes	M	TIGRFAM outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
TLS3_k127_23723_4	1305737.JAFX01000001_gene997	6.291e-75	257.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,47JNP@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
TLS3_k127_23723_7	755732.Fluta_2089	9.532e-53	187.0	COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,1I2SJ@117743|Flavobacteriia,2PAY2@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM Iron-sulfur cluster assembly accessory protein	sufA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
TLS3_k127_23723_0	755732.Fluta_2088	2.855e-284	876.0	COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,1HWKU@117743|Flavobacteriia,2PA9Y@246874|Cryomorphaceae	976|Bacteroidetes	O	Uncharacterized protein family (UPF0051)	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
TLS3_k127_23723_1	755732.Fluta_2087	6.12e-134	430.0	COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes,1HWTU@117743|Flavobacteriia,2PAMD@246874|Cryomorphaceae	976|Bacteroidetes	O	ATPases associated with a variety of cellular activities	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
TLS3_k127_23723_2	755732.Fluta_2086	2.222e-120	399.0	COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,1HXNA@117743|Flavobacteriia,2PAU0@246874|Cryomorphaceae	976|Bacteroidetes	O	Uncharacterized protein family (UPF0051)	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
TLS3_k127_23723_8	755732.Fluta_1045	2.037e-36	147.0	2EQMK@1|root,30R0R@2|Bacteria,4PD8V@976|Bacteroidetes,1IFUG@117743|Flavobacteriia,2PC2A@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_23723_11	755732.Fluta_1046	6.274e-05	54.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_6,SBP_bac_8
TLS3_k127_23723_10	228405.HNE_0478	2.819e-07	55.0	2DEJE@1|root,2ZN82@2|Bacteria,1PB33@1224|Proteobacteria,2UY1B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_23723_3	755732.Fluta_1048	1.69e-86	298.0	2A92F@1|root,30Y6G@2|Bacteria,4PBXE@976|Bacteroidetes,1IMRH@117743|Flavobacteriia,2PBQ0@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_23723_6	755732.Fluta_1050	4.354e-53	193.0	COG1595@1|root,COG1595@2|Bacteria,4NKHT@976|Bacteroidetes,1IG88@117743|Flavobacteriia,2PB14@246874|Cryomorphaceae	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_23723_9	1509405.GV67_03265	1.925e-07	59.0	COG2062@1|root,COG2062@2|Bacteria,1RIVH@1224|Proteobacteria,2UD85@28211|Alphaproteobacteria,4BDBZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	phosphohistidine phosphatase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
TLS3_k127_23723_5	755732.Fluta_1052	8.161e-72	250.0	COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,1HXF0@117743|Flavobacteriia,2PAYY@246874|Cryomorphaceae	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TLS3_k127_2378521_1	755732.Fluta_0921	9.882e-97	325.0	COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,1HXG8@117743|Flavobacteriia,2PAWA@246874|Cryomorphaceae	976|Bacteroidetes	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
TLS3_k127_2378521_6	1189619.pgond44_14828	4.747e-18	91.0	2CK2S@1|root,32TQP@2|Bacteria,4NTHR@976|Bacteroidetes,1I3XM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
TLS3_k127_2378521_7	1469557.JSWF01000032_gene3231	2.345e-16	93.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein
TLS3_k127_2378521_0	1356852.N008_08500	1.447e-217	717.0	COG1404@1|root,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,47X9G@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Peptidase_S8
TLS3_k127_2378521_4	1313421.JHBV01000028_gene1857	3.478e-27	127.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
TLS3_k127_2378521_3	755732.Fluta_0920	5.915e-77	268.0	COG3064@1|root,COG3064@2|Bacteria,4NM6Q@976|Bacteroidetes,1INKQ@117743|Flavobacteriia,2PBQE@246874|Cryomorphaceae	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_2378521_2	755732.Fluta_0919	3.98e-84	288.0	COG3405@1|root,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_15,CHU_C,DUF11,Glyco_hydro_8
TLS3_k127_2392058_3	1122176.KB903564_gene3182	0.0007567	47.0	2DZG9@1|root,32V9U@2|Bacteria,4NSRV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2392058_1	616991.JPOO01000003_gene1718	7.468e-54	191.0	COG4898@1|root,COG4898@2|Bacteria,4NQ4W@976|Bacteroidetes,1I2X2@117743|Flavobacteriia,23HGT@178469|Arenibacter	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
TLS3_k127_2392058_0	269798.CHU_2833	6.96e-111	387.0	2DB7X@1|root,2Z7P2@2|Bacteria,4PQ20@976|Bacteroidetes,47NPR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2392058_2	485918.Cpin_0315	7.554e-42	168.0	28JKB@1|root,310Q2@2|Bacteria,4NQ1D@976|Bacteroidetes,1IXFS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2393394_1	1120951.AUBG01000011_gene2412	1.507e-85	285.0	COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,1HX4Z@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0176 family	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
TLS3_k127_2393394_0	755732.Fluta_3634	4.925e-221	692.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,1HXZ0@117743|Flavobacteriia,2PAGJ@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Mur ligase family, catalytic domain	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_2393394_2	1408433.JHXV01000030_gene1399	5.15e-78	270.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1HXDG@117743|Flavobacteriia,2PBQ1@246874|Cryomorphaceae	976|Bacteroidetes	H	ApbE family	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
TLS3_k127_239413_0	755732.Fluta_0798	4.805e-200	633.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1HWYD@117743|Flavobacteriia,2PAG3@246874|Cryomorphaceae	976|Bacteroidetes	L	UvrD-like helicase C-terminal domain	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
TLS3_k127_2402484_9	1396141.BATP01000047_gene3903	7.812e-21	94.0	COG0457@1|root,COG3118@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,COG3379@2|Bacteria,46URB@74201|Verrucomicrobia,2IV4Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
TLS3_k127_2402484_6	1250278.JQNQ01000001_gene3488	1.578e-57	207.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1HXJ2@117743|Flavobacteriia	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TLS3_k127_2402484_7	755732.Fluta_0011	8.161e-48	174.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,1I34F@117743|Flavobacteriia,2PBX8@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
TLS3_k127_2402484_3	1121374.KB891576_gene670	6.678e-144	462.0	COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,1RNRN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phenylacetate-CoA oxygenase	paaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	iEC55989_1330.EC55989_1524,iECO111_1330.ECO111_1782,iECO26_1355.ECO26_1992,iEcE24377_1341.EcE24377A_1573	PaaA_PaaC
TLS3_k127_2402484_11	1121479.AUBS01000002_gene3612	5.615e-05	53.0	292D1@1|root,2ZPXC@2|Bacteria,1REHR@1224|Proteobacteria,2U7EA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2402484_8	1408433.JHXV01000026_gene3061	6.004e-34	132.0	COG3460@1|root,COG3460@2|Bacteria,4NQFV@976|Bacteroidetes,1I2UD@117743|Flavobacteriia,2PB3H@246874|Cryomorphaceae	976|Bacteroidetes	Q	Phenylacetic acid degradation B	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
TLS3_k127_2402484_5	760192.Halhy_3789	6.474e-67	235.0	COG3396@1|root,COG3396@2|Bacteria,4NFIT@976|Bacteroidetes,1IX3A@117747|Sphingobacteriia	976|Bacteroidetes	S	Phenylacetic acid catabolic protein	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
TLS3_k127_2402484_4	755732.Fluta_3133	8.182e-93	310.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,1HY4W@117743|Flavobacteriia,2PAYN@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, crp family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TLS3_k127_2402484_1	706436.HMPREF9074_08860	7.048e-171	548.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,1HYDQ@117743|Flavobacteriia,1EQZE@1016|Capnocytophaga	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
TLS3_k127_2402484_0	1313421.JHBV01000030_gene2069	4.693e-214	689.0	COG2217@1|root,COG2217@2|Bacteria,4NEI1@976|Bacteroidetes,1IPQU@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
TLS3_k127_2402484_10	755732.Fluta_3129	1.895e-15	78.0	COG3197@1|root,COG3197@2|Bacteria,4NUR7@976|Bacteroidetes,1I562@117743|Flavobacteriia,2PB7Y@246874|Cryomorphaceae	976|Bacteroidetes	P	TIGRFAM cytochrome oxidase maturation protein, cbb3-type	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
TLS3_k127_2402484_2	755732.Fluta_3128	1.039e-154	491.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1HWQ5@117743|Flavobacteriia,2PAJX@246874|Cryomorphaceae	976|Bacteroidetes	C	Cytochrome C and Quinol oxidase polypeptide I	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
TLS3_k127_2416666_1	1313421.JHBV01000030_gene2025	4.213e-41	158.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,1IY8A@117747|Sphingobacteriia	976|Bacteroidetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_2416666_0	1046627.BZARG_2515	6.611e-43	164.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1HX1Z@117743|Flavobacteriia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
TLS3_k127_2429811_1	755732.Fluta_2149	6.696e-218	679.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1HWV4@117743|Flavobacteriia,2PAJV@246874|Cryomorphaceae	976|Bacteroidetes	C	Acyl-CoA dehydrogenase, N-terminal domain	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_2429811_7	755732.Fluta_2148	5.412e-78	263.0	COG0503@1|root,COG0503@2|Bacteria,4NP7K@976|Bacteroidetes,1I29Z@117743|Flavobacteriia,2PBP0@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
TLS3_k127_2429811_10	755732.Fluta_2147	2.714e-45	175.0	COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,1IGDC@117743|Flavobacteriia,2PB7W@246874|Cryomorphaceae	976|Bacteroidetes	L	Helix-hairpin-helix motif	comEA	-	-	-	-	-	-	-	-	-	-	-	HHH_3
TLS3_k127_2429811_2	391587.KAOT1_01340	4.143e-205	653.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1HXM9@117743|Flavobacteriia	976|Bacteroidetes	E	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
TLS3_k127_2429811_12	509191.AEDB02000064_gene549	2.18e-16	90.0	COG3858@1|root,COG4642@1|root,COG3858@2|Bacteria,COG4642@2|Bacteria,1TRNW@1239|Firmicutes,24GQA@186801|Clostridia,3WMGZ@541000|Ruminococcaceae	186801|Clostridia	S	Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases.	-	-	-	-	-	-	-	-	-	-	-	-	MORN
TLS3_k127_2429811_6	755732.Fluta_2146	1.294e-97	328.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1HXB2@117743|Flavobacteriia,2PAPS@246874|Cryomorphaceae	976|Bacteroidetes	M	Male sterility protein	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
TLS3_k127_2429811_5	1408433.JHXV01000007_gene2890	1.353e-110	366.0	COG1226@1|root,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,1HXU2@117743|Flavobacteriia,2PBGA@246874|Cryomorphaceae	976|Bacteroidetes	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
TLS3_k127_2429811_11	755732.Fluta_2145	5.738e-31	123.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	pspC	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0016020,GO:0019222,GO:0044464,GO:0048518,GO:0050789,GO:0060255,GO:0065007,GO:0071944	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
TLS3_k127_2429811_8	755732.Fluta_2144	4.599e-71	254.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1HWT2@117743|Flavobacteriia,2PAQM@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
TLS3_k127_2429811_0	755732.Fluta_2099	3.96e-265	833.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia,2PACJ@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
TLS3_k127_2429811_4	755732.Fluta_2098	1.868e-163	520.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,1HY12@117743|Flavobacteriia,2PAE0@246874|Cryomorphaceae	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS3_k127_2429811_3	755732.Fluta_2097	3.142e-199	644.0	28M1N@1|root,2ZAGE@2|Bacteria,4NIDD@976|Bacteroidetes,1I8D6@117743|Flavobacteriia,2PARN@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2429811_9	755732.Fluta_2096	8.018e-65	231.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,1I0RX@117743|Flavobacteriia,2PB43@246874|Cryomorphaceae	976|Bacteroidetes	S	PASTA	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
TLS3_k127_2429811_13	1124780.ANNU01000006_gene2951	9.607e-06	47.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,47M0E@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
TLS3_k127_2455161_7	945713.IALB_3055	1.1e-70	250.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	enhA_1	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
TLS3_k127_2455161_10	1122179.KB890453_gene4595	9.335e-21	94.0	COG3292@1|root,COG3292@2|Bacteria,4NI2T@976|Bacteroidetes	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
TLS3_k127_2455161_0	865937.Gilli_0181	1.682e-290	902.0	COG0626@1|root,COG0626@2|Bacteria,4NEWX@976|Bacteroidetes,1HX3T@117743|Flavobacteriia,2P60W@244698|Gillisia	976|Bacteroidetes	E	PFAM Cys Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
TLS3_k127_2455161_9	1121898.Q766_03030	2.173e-34	136.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I23H@117743|Flavobacteriia,2P06D@237|Flavobacterium	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
TLS3_k127_2455161_4	1166018.FAES_3851	7.471e-94	310.0	COG0664@1|root,COG0664@2|Bacteria,4NNYU@976|Bacteroidetes,47XMY@768503|Cytophagia	976|Bacteroidetes	T	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
TLS3_k127_2455161_5	1166018.FAES_3852	5.587e-89	297.0	28Q2T@1|root,2ZCKN@2|Bacteria,4NMAB@976|Bacteroidetes,47T94@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2455161_2	1121012.AUKX01000070_gene1855	1.03e-132	432.0	COG0642@1|root,COG2205@2|Bacteria,4NFYN@976|Bacteroidetes,1HZ6X@117743|Flavobacteriia,23I0R@178469|Arenibacter	976|Bacteroidetes	T	Domain of unknown function (DUF4118)	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
TLS3_k127_2455161_8	1122915.AUGY01000047_gene1453	3.958e-69	241.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,4HEFU@91061|Bacilli,26UDP@186822|Paenibacillaceae	91061|Bacilli	T	XRE family transcriptional regulator	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_2455161_1	1392490.JHZX01000001_gene3539	2.964e-258	804.0	COG0168@1|root,COG0168@2|Bacteria,4NGFY@976|Bacteroidetes,1I0YZ@117743|Flavobacteriia	976|Bacteroidetes	P	Cation transport protein	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
TLS3_k127_2455161_3	1392490.JHZX01000001_gene3540	2.471e-115	377.0	COG0569@1|root,COG0569@2|Bacteria,4NIFS@976|Bacteroidetes,1HXG9@117743|Flavobacteriia	976|Bacteroidetes	P	Putative NAD(P)-binding	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
TLS3_k127_2455161_6	1123057.P872_07510	3.893e-74	253.0	2CB8G@1|root,2Z88H@2|Bacteria,4NF68@976|Bacteroidetes,47M04@768503|Cytophagia	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
TLS3_k127_2464176_2	1313421.JHBV01000008_gene4375	7.228e-52	192.0	28KF6@1|root,2ZA1E@2|Bacteria,4NM2F@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	ko:K16905	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	-
TLS3_k127_2464176_3	1408433.JHXV01000012_gene3940	4.442e-46	175.0	COG1668@1|root,COG1668@2|Bacteria,4NNAU@976|Bacteroidetes,1I8JV@117743|Flavobacteriia	976|Bacteroidetes	CP	transmembrane transport	-	-	-	ko:K16906	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	-
TLS3_k127_2464176_0	1168034.FH5T_01065	5.52e-120	391.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0015562,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0050896,GO:0051179,GO:0051234,GO:0055085	-	ko:K16907	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_2464176_1	1313421.JHBV01000008_gene4372	1.346e-62	222.0	COG1309@1|root,COG1309@2|Bacteria,4P0WG@976|Bacteroidetes	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_2472363_0	755732.Fluta_2012	0.0	1322.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1IG7B@117743|Flavobacteriia,2PBE8@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_2472363_1	755732.Fluta_2018	2.796e-87	293.0	COG1917@1|root,COG1917@2|Bacteria,4PKJ0@976|Bacteroidetes,1IJAI@117743|Flavobacteriia,2PAU2@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
TLS3_k127_2472363_2	755732.Fluta_2019	5.821e-32	127.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4P1A1@976|Bacteroidetes	2|Bacteria	E	Pkd domain containing protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,HYR,MAM,PKD,Peptidase_M43,Peptidase_S8,SprB,fn3
TLS3_k127_2533237_2	760192.Halhy_0958	1.399e-48	178.0	29E7I@1|root,3015I@2|Bacteria,4NNFG@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
TLS3_k127_2533237_0	620914.JH621300_gene3542	1.94e-118	389.0	COG1988@1|root,COG1988@2|Bacteria,4NFBT@976|Bacteroidetes,1HY38@117743|Flavobacteriia,2YJ4Z@290174|Aquimarina	976|Bacteroidetes	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
TLS3_k127_2533237_1	980584.AFPB01000173_gene1755	1.164e-79	277.0	COG3146@1|root,COG3146@2|Bacteria,4NI7H@976|Bacteroidetes,1I0KW@117743|Flavobacteriia,4070X@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	S	8-amino-7-oxononanoate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB_like
TLS3_k127_254248_1	755732.Fluta_1208	0.0	1317.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia,2PA9I@246874|Cryomorphaceae	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
TLS3_k127_254248_6	592029.DDD_2102	1.918e-221	696.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,1HY1F@117743|Flavobacteriia,3HJPI@363408|Nonlabens	976|Bacteroidetes	J	DALR_2	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
TLS3_k127_254248_14	1229487.AMYW01000001_gene4023	2.258e-29	120.0	COG3093@1|root,COG3093@2|Bacteria,4PAC0@976|Bacteroidetes,1IA2J@117743|Flavobacteriia	976|Bacteroidetes	K	addiction module antidote protein HigA	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_254248_13	1229487.AMYW01000001_gene4023	6.971e-30	122.0	COG3093@1|root,COG3093@2|Bacteria,4PAC0@976|Bacteroidetes,1IA2J@117743|Flavobacteriia	976|Bacteroidetes	K	addiction module antidote protein HigA	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_254248_2	755732.Fluta_3104	0.0	1246.0	COG3291@1|root,COG3291@2|Bacteria,4PI0I@976|Bacteroidetes,1I5WG@117743|Flavobacteriia,2PBH4@246874|Cryomorphaceae	2|Bacteria	S	C-terminal domain of CHU protein family	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_254248_11	755732.Fluta_3105	4.082e-92	313.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_254248_0	755732.Fluta_3106	0.0	1401.0	COG3291@1|root,COG3291@2|Bacteria,4PI0I@976|Bacteroidetes,1I5WG@117743|Flavobacteriia,2PBH4@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_254248_9	755732.Fluta_3107	3.635e-137	443.0	COG4772@1|root,COG4772@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014,ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.2	-	-	Plug,PorP_SprF,STN,TonB_dep_Rec
TLS3_k127_254248_5	755732.Fluta_3108	5.402e-228	727.0	COG1729@1|root,COG2885@1|root,COG1729@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia,2PBBP@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
TLS3_k127_254248_3	755732.Fluta_1479	5.184e-301	930.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,1HX3S@117743|Flavobacteriia,2PAHM@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
TLS3_k127_254248_15	746697.Aeqsu_1821	1.068e-22	107.0	2E61B@1|root,32DNU@2|Bacteria,4NQ9X@976|Bacteroidetes,1I39V@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_254248_10	1121904.ARBP01000002_gene7078	2.411e-118	400.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,47N1D@768503|Cytophagia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	LAB_N,PMT,PMT_2
TLS3_k127_254248_4	755732.Fluta_1459	1.817e-272	845.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HYE9@117743|Flavobacteriia,2PAEZ@246874|Cryomorphaceae	976|Bacteroidetes	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
TLS3_k127_254248_12	391587.KAOT1_10501	3.08e-51	188.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,YkuD
TLS3_k127_254248_16	945713.IALB_1477	0.000189	51.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
TLS3_k127_254248_8	755732.Fluta_1266	6.946e-155	501.0	COG1721@1|root,COG1721@2|Bacteria,4NE10@976|Bacteroidetes,1HXIV@117743|Flavobacteriia,2PACR@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TLS3_k127_254248_7	755732.Fluta_1265	4.41e-161	515.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HXA1@117743|Flavobacteriia,2PAM8@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TLS3_k127_2565033_0	1408433.JHXV01000005_gene2415	0.0	1277.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1HY4P@117743|Flavobacteriia,2PAE2@246874|Cryomorphaceae	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
TLS3_k127_2565033_1	1408433.JHXV01000005_gene2416	0.0	1241.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1HWVR@117743|Flavobacteriia,2PAAQ@246874|Cryomorphaceae	976|Bacteroidetes	O	ATPase family associated with various cellular activities (AAA)	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
TLS3_k127_2565033_2	926562.Oweho_0959	8.399e-38	143.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1HXU4@117743|Flavobacteriia,2PA99@246874|Cryomorphaceae	976|Bacteroidetes	H	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS
TLS3_k127_2586342_1	1313421.JHBV01000030_gene2179	9.48e-06	50.0	COG2010@1|root,COG2010@2|Bacteria,4NEEJ@976|Bacteroidetes,1IP2H@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,FlgD_ig
TLS3_k127_2586342_0	755732.Fluta_1595	3.635e-152	493.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,1HXSR@117743|Flavobacteriia,2PBCV@246874|Cryomorphaceae	976|Bacteroidetes	M	tail specific protease	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
TLS3_k127_262564_24	1122176.KB903587_gene4515	1.659e-16	94.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF5011,HYR,Laminin_G_3,SprB
TLS3_k127_262564_16	1122225.AULQ01000002_gene492	3.883e-56	223.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJU9@976|Bacteroidetes	976|Bacteroidetes	MU	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,PKD
TLS3_k127_262564_23	1233951.IO90_14085	1.258e-16	95.0	COG3227@1|root,COG5492@1|root,COG3227@2|Bacteria,COG5492@2|Bacteria,4PI37@976|Bacteroidetes,1IG7Q@117743|Flavobacteriia,3HIP6@358033|Chryseobacterium	976|Bacteroidetes	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_262564_0	755732.Fluta_1747	0.0	1450.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1HY4A@117743|Flavobacteriia,2PAA7@246874|Cryomorphaceae	976|Bacteroidetes	J	PFAM tRNA synthetases class I (I, L, M and V)	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
TLS3_k127_262564_4	755732.Fluta_1745	1.791e-213	685.0	COG0457@1|root,COG2972@1|root,COG0457@2|Bacteria,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,1HXAW@117743|Flavobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,TPR_12
TLS3_k127_262564_8	755732.Fluta_1744	4.781e-118	384.0	COG3279@1|root,COG3279@2|Bacteria,4NNHE@976|Bacteroidetes,1HZAH@117743|Flavobacteriia,2PATW@246874|Cryomorphaceae	976|Bacteroidetes	K	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_262564_12	1453498.LG45_13955	3.625e-79	272.0	COG1878@1|root,COG1878@2|Bacteria,4NFXM@976|Bacteroidetes,1HWQP@117743|Flavobacteriia,2NSD1@237|Flavobacterium	976|Bacteroidetes	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
TLS3_k127_262564_25	1296416.JACB01000062_gene3827	3.241e-15	85.0	COG2353@1|root,COG2353@2|Bacteria,4NMFT@976|Bacteroidetes,1I1D2@117743|Flavobacteriia,2YHX2@290174|Aquimarina	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_262564_17	755732.Fluta_1297	1.263e-53	195.0	COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,1I176@117743|Flavobacteriia,2PB75@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	yihX	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
TLS3_k127_262564_19	755732.Fluta_1296	2.105e-47	174.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,1I1YS@117743|Flavobacteriia,2PAUV@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
TLS3_k127_262564_6	755732.Fluta_1295	1.346e-123	400.0	29UMW@1|root,30FZE@2|Bacteria,4NP3W@976|Bacteroidetes,1IMQI@117743|Flavobacteriia,2PBDZ@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_262564_5	755732.Fluta_1294	4.986e-197	631.0	COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes,1HWV6@117743|Flavobacteriia,2PBAH@246874|Cryomorphaceae	976|Bacteroidetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
TLS3_k127_262564_1	755732.Fluta_1293	0.0	1054.0	COG1629@1|root,COG1629@2|Bacteria,4PN6V@976|Bacteroidetes,1IKDC@117743|Flavobacteriia,2PBH7@246874|Cryomorphaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_262564_14	755732.Fluta_1369	1.949e-73	256.0	28IS5@1|root,2Z8RB@2|Bacteria,4NIIH@976|Bacteroidetes,1HZWV@117743|Flavobacteriia,2PBT8@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_262564_7	755732.Fluta_1368	2.773e-119	392.0	COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,1HXDH@117743|Flavobacteriia,2PAFA@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS3_k127_262564_22	553178.CAPGI0001_2193	2.474e-23	104.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,1I49T@117743|Flavobacteriia,1ES0P@1016|Capnocytophaga	976|Bacteroidetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
TLS3_k127_262564_9	755732.Fluta_2890	5.726e-106	371.0	COG4783@1|root,COG4783@2|Bacteria,4NM0X@976|Bacteroidetes,1I0RP@117743|Flavobacteriia,2PARX@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TLS3_k127_262564_10	755732.Fluta_1900	2.426e-93	311.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,1HWRQ@117743|Flavobacteriia,2PAZ9@246874|Cryomorphaceae	976|Bacteroidetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
TLS3_k127_262564_2	755732.Fluta_1899	1.687e-232	724.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,1HWXE@117743|Flavobacteriia,2PA7W@246874|Cryomorphaceae	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_262564_21	755732.Fluta_1898	1.748e-37	141.0	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,1I3VI@117743|Flavobacteriia,2PB4S@246874|Cryomorphaceae	976|Bacteroidetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TLS3_k127_262564_11	1237149.C900_03318	2.349e-90	304.0	COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes,47KJ2@768503|Cytophagia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
TLS3_k127_262564_18	755732.Fluta_1897	7.364e-49	180.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1I19R@117743|Flavobacteriia,2PAVI@246874|Cryomorphaceae	976|Bacteroidetes	F	Formyl transferase	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
TLS3_k127_262564_13	755732.Fluta_1896	4.214e-76	261.0	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,1HXJM@117743|Flavobacteriia,2PASH@246874|Cryomorphaceae	976|Bacteroidetes	U	PFAM MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
TLS3_k127_262564_3	755732.Fluta_1335	5.335e-217	687.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia,2PBC5@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TPR_16,TPR_8
TLS3_k127_262564_15	755732.Fluta_1336	4.645e-61	218.0	COG1280@1|root,COG1280@2|Bacteria,4NH3F@976|Bacteroidetes,1HYQ9@117743|Flavobacteriia,2PB3K@246874|Cryomorphaceae	976|Bacteroidetes	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
TLS3_k127_262564_20	755732.Fluta_1337	1.331e-44	165.0	2BV93@1|root,32QNV@2|Bacteria,4PCDT@976|Bacteroidetes,1ID03@117743|Flavobacteriia,2PC4F@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_262564_26	1121897.AUGO01000015_gene3330	3.85e-13	76.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,4NFZQ@976|Bacteroidetes,1HWXQ@117743|Flavobacteriia,2NTDA@237|Flavobacterium	976|Bacteroidetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
TLS3_k127_269221_4	641524.ADICYQ_5796	1.537e-48	177.0	COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,47MKU@768503|Cytophagia	976|Bacteroidetes	M	Transglycosylase SLT domain	mltD_2	-	-	-	-	-	-	-	-	-	-	-	SLT
TLS3_k127_269221_0	755732.Fluta_2049	0.0	1456.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,1HXMR@117743|Flavobacteriia,2PAAM@246874|Cryomorphaceae	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
TLS3_k127_269221_6	755732.Fluta_3073	4.491e-36	148.0	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,1IM58@117743|Flavobacteriia,2PBXV@246874|Cryomorphaceae	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_7
TLS3_k127_269221_1	755732.Fluta_2075	4.833e-209	655.0	COG0304@1|root,COG0304@2|Bacteria,4NDVU@976|Bacteroidetes,1I0BZ@117743|Flavobacteriia,2PC6C@246874|Cryomorphaceae	976|Bacteroidetes	I	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_269221_5	755732.Fluta_2076	2.639e-44	162.0	COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,1I2WQ@117743|Flavobacteriia,2PB2C@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM FeS assembly SUF system protein	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
TLS3_k127_269221_3	755732.Fluta_2077	1.813e-61	214.0	COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,1I187@117743|Flavobacteriia,2PAUU@246874|Cryomorphaceae	976|Bacteroidetes	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
TLS3_k127_269221_2	755732.Fluta_2078	4.74e-151	483.0	COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,1HWSI@117743|Flavobacteriia,2PAEG@246874|Cryomorphaceae	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
TLS3_k127_2706024_0	1229487.AMYW01000027_gene2799	5.868e-245	764.0	COG3501@1|root,COG3501@2|Bacteria,4NFPB@976|Bacteroidetes,1HZN7@117743|Flavobacteriia,2NU7J@237|Flavobacterium	976|Bacteroidetes	S	Rhs element Vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
TLS3_k127_2706024_1	388413.ALPR1_12735	3.612e-27	111.0	COG1652@1|root,COG1652@2|Bacteria,4NJV3@976|Bacteroidetes,47R3Z@768503|Cytophagia	976|Bacteroidetes	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2718130_2	755732.Fluta_3615	1.538e-172	552.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1HXEF@117743|Flavobacteriia,2PAER@246874|Cryomorphaceae	976|Bacteroidetes	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
TLS3_k127_2718130_4	1121904.ARBP01000026_gene628	1.144e-87	298.0	COG3228@1|root,COG3228@2|Bacteria,4NGM9@976|Bacteroidetes,47PJA@768503|Cytophagia	976|Bacteroidetes	U	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90,SEC-C
TLS3_k127_2718130_0	755732.Fluta_3952	2.242e-194	611.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1HYBS@117743|Flavobacteriia,2PA7Y@246874|Cryomorphaceae	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
TLS3_k127_2718130_3	1121899.Q764_02190	4.722e-112	373.0	COG0665@1|root,COG0665@2|Bacteria,4NEEY@976|Bacteroidetes,1HZ4W@117743|Flavobacteriia,2NT6F@237|Flavobacterium	976|Bacteroidetes	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
TLS3_k127_2718130_1	755732.Fluta_3635	9.208e-181	631.0	COG0457@1|root,COG0457@2|Bacteria,4P3PK@976|Bacteroidetes,1ICNQ@117743|Flavobacteriia,2PBCJ@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2756396_5	1408433.JHXV01000023_gene3302	8.41e-73	266.0	COG3291@1|root,COG3291@2|Bacteria,4PBW3@976|Bacteroidetes,1ICPP@117743|Flavobacteriia,2PBJ2@246874|Cryomorphaceae	976|Bacteroidetes	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA
TLS3_k127_2756396_2	1408433.JHXV01000020_gene3513	7.668e-142	452.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,1HYVV@117743|Flavobacteriia,2PAAP@246874|Cryomorphaceae	976|Bacteroidetes	C	Succinate dehydrogenase fumarate reductase Fe-S protein subunit	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
TLS3_k127_2756396_0	1380384.JADN01000004_gene2146	0.0	1174.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,1HWUS@117743|Flavobacteriia	976|Bacteroidetes	C	SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
TLS3_k127_2756396_3	1121912.AUHD01000003_gene3038	1.694e-99	329.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,1HWPS@117743|Flavobacteriia	976|Bacteroidetes	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
TLS3_k127_2756396_6	445961.IW15_06710	0.0006157	48.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	CP_1072	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
TLS3_k127_2756396_1	984262.SGRA_0120	8.001e-143	485.0	COG2374@1|root,COG3291@1|root,COG2374@2|Bacteria,COG3291@2|Bacteria,4NT6S@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,SprB
TLS3_k127_2756396_4	1408433.JHXV01000006_gene2713	8.719e-83	284.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,1HXC6@117743|Flavobacteriia,2PARC@246874|Cryomorphaceae	976|Bacteroidetes	V	LD-carboxypeptidase	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
TLS3_k127_275819_6	1501230.ET33_17590	2.678e-05	49.0	COG1609@1|root,COG1609@2|Bacteria,1TPH2@1239|Firmicutes,4HC2P@91061|Bacilli,26TX9@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
TLS3_k127_275819_2	714943.Mucpa_6953	3.123e-84	284.0	COG2823@1|root,COG2823@2|Bacteria,4NJ6H@976|Bacteroidetes,1IUKC@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG2823 periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
TLS3_k127_275819_4	755732.Fluta_1655	7.191e-62	224.0	COG1090@1|root,COG1090@2|Bacteria,4NINM@976|Bacteroidetes,1HXRB@117743|Flavobacteriia,2PAWB@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM NAD dependent epimerase dehydratase family	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
TLS3_k127_275819_5	755732.Fluta_1837	1.274e-46	175.0	COG0454@1|root,COG0456@2|Bacteria,4NNJS@976|Bacteroidetes,1I258@117743|Flavobacteriia,2PB47@246874|Cryomorphaceae	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
TLS3_k127_275819_0	755732.Fluta_1836	0.0	3144.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia,2PA61@246874|Cryomorphaceae	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
TLS3_k127_275819_3	755732.Fluta_1835	3.944e-84	282.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,1HX6W@117743|Flavobacteriia,2PB2K@246874|Cryomorphaceae	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
TLS3_k127_275819_1	755732.Fluta_1834	0.0	1218.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1HXS7@117743|Flavobacteriia,2PA8M@246874|Cryomorphaceae	976|Bacteroidetes	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
TLS3_k127_2776671_0	755732.Fluta_3616	5.166e-173	550.0	COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,1HWVY@117743|Flavobacteriia,2PAAA@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Alanine dehydrogenase PNT, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
TLS3_k127_2776671_1	755732.Fluta_3617	8.042e-77	264.0	COG1778@1|root,COG1778@2|Bacteria,4NGXC@976|Bacteroidetes,1HX0H@117743|Flavobacteriia,2PAX2@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	-	-	2.7.7.43,2.7.7.92,3.1.3.45	ko:K03270,ko:K21749	ko00520,ko00540,ko01100,map00520,map00540,map01100	M00063	R01117,R03350,R04215	RC00017,RC00152	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3,Hydrolase_3
TLS3_k127_2776671_2	755732.Fluta_3618	1.213e-70	240.0	COG2876@1|root,COG2876@2|Bacteria,4NH82@976|Bacteroidetes,1I8SQ@117743|Flavobacteriia,2PARW@246874|Cryomorphaceae	976|Bacteroidetes	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
TLS3_k127_2781719_6	1121373.KB903650_gene1466	2.213e-05	57.0	COG3345@1|root,COG3507@1|root,COG3693@1|root,COG3345@2|Bacteria,COG3507@2|Bacteria,COG3693@2|Bacteria	2|Bacteria	G	endo-1,4-beta-xylanase activity	rafA	-	3.2.1.22,3.2.1.4	ko:K01179,ko:K07407	ko00052,ko00500,ko00561,ko00600,ko00603,ko01100,map00052,map00500,map00561,map00600,map00603,map01100	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091,R06200,R11307,R11308	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	GH5,GH9	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase,Melibiase_2,RicinB_lectin_2,Ricin_B_lectin
TLS3_k127_2781719_0	755732.Fluta_2458	3.384e-149	488.0	2DBNY@1|root,2ZA6F@2|Bacteria,4NH2P@976|Bacteroidetes,1I47S@117743|Flavobacteriia,2PAQ9@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2781719_3	1297865.APJD01000030_gene1680	6.605e-53	207.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TRFP@28211|Alphaproteobacteria,3K0MF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Beta-lactamase	dap	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Beta-lactamase,DAP_B
TLS3_k127_2781719_1	755732.Fluta_3639	1.179e-94	313.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,1HY4S@117743|Flavobacteriia,2PATV@246874|Cryomorphaceae	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
TLS3_k127_2781719_4	1168289.AJKI01000042_gene3726	2.829e-52	193.0	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,2FSYM@200643|Bacteroidia,3XJRK@558415|Marinilabiliaceae	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
TLS3_k127_2781719_2	313606.M23134_01162	2.547e-65	230.0	COG3279@1|root,COG3279@2|Bacteria,4NFZT@976|Bacteroidetes,47PX6@768503|Cytophagia	976|Bacteroidetes	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_2781719_5	1122179.KB890416_gene2690	3.587e-30	125.0	COG2972@1|root,COG2972@2|Bacteria,4NMDQ@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_278929_0	983544.Lacal_2035	2.814e-189	600.0	COG1672@1|root,COG1672@2|Bacteria,4NGWE@976|Bacteroidetes,1I6TA@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	AAA_14,ATPase_2,DUF234
TLS3_k127_278929_1	1313421.JHBV01000008_gene4397	3.776e-37	156.0	COG4886@1|root,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes,1IZK8@117747|Sphingobacteriia	976|Bacteroidetes	M	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4
TLS3_k127_278929_4	1121288.AULL01000014_gene2177	0.0008608	51.0	COG3866@1|root,COG4886@1|root,COG5263@1|root,COG3866@2|Bacteria,COG4886@2|Bacteria,COG5263@2|Bacteria,4NHZ1@976|Bacteroidetes,1HZ7I@117743|Flavobacteriia,3ZQ4P@59732|Chryseobacterium	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase_C
TLS3_k127_278929_2	1406840.Q763_17395	2.776e-30	134.0	COG3291@1|root,COG3291@2|Bacteria,4PI2H@976|Bacteroidetes,1IA3E@117743|Flavobacteriia,2NXN5@237|Flavobacterium	976|Bacteroidetes	DZ	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_278929_3	592029.DDD_1329	9.243e-05	46.0	COG4447@1|root,COG4447@2|Bacteria,4PM0K@976|Bacteroidetes,1I2DM@117743|Flavobacteriia,3HJGH@363408|Nonlabens	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
TLS3_k127_280884_1	313612.L8106_13010	0.0001392	51.0	COG3224@1|root,COG3224@2|Bacteria,1G83R@1117|Cyanobacteria,1HC4F@1150|Oscillatoriales	1117|Cyanobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_280884_0	246197.MXAN_6806	2.497e-33	140.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	estX	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
TLS3_k127_2818646_5	525897.Dbac_1179	2.025e-09	60.0	2EMKC@1|root,33F8T@2|Bacteria,1NP5C@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2818646_4	1122947.FR7_2670	2.913e-10	61.0	COG0753@1|root,COG0753@2|Bacteria,1TPPV@1239|Firmicutes,4H784@909932|Negativicutes	909932|Negativicutes	C	Catalase	-	-	-	-	-	-	-	-	-	-	-	-	Catalase,Catalase-rel
TLS3_k127_2818646_0	1121405.dsmv_3617	2.249e-32	129.0	2FA9U@1|root,342II@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2818646_3	1499967.BAYZ01000036_gene2428	2.947e-16	85.0	2F3F7@1|root,33W90@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2844301_1	755732.Fluta_1200	1.096e-174	553.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,1HXSA@117743|Flavobacteriia,2PAJH@246874|Cryomorphaceae	976|Bacteroidetes	I	B12 binding domain	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
TLS3_k127_2844301_8	755732.Fluta_1201	3.69e-67	237.0	2A607@1|root,30USF@2|Bacteria,4PFQT@976|Bacteroidetes,1IMS2@117743|Flavobacteriia,2PBUU@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2844301_15	755732.Fluta_1202	2.792e-18	87.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	divIC	-	-	ko:K05589,ko:K12065,ko:K13052	-	-	-	-	ko00000,ko02044,ko03036	3.A.7.11.1	-	-	DivIC
TLS3_k127_2844301_3	755732.Fluta_1203	1.487e-107	361.0	COG2385@1|root,COG2385@2|Bacteria,4NG21@976|Bacteroidetes,1I7GW@117743|Flavobacteriia,2PAW4@246874|Cryomorphaceae	976|Bacteroidetes	D	Stage II sporulation protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	DUF4922,Glycos_transf_2,SpoIID
TLS3_k127_2844301_2	1453498.LG45_06365	7.65e-134	437.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,1HWRS@117743|Flavobacteriia,2NSD5@237|Flavobacterium	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
TLS3_k127_2844301_4	755732.Fluta_1206	1.083e-106	351.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,1HWSV@117743|Flavobacteriia,2PAN6@246874|Cryomorphaceae	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
TLS3_k127_2844301_10	755732.Fluta_2424	7.951e-61	215.0	COG2318@1|root,COG2318@2|Bacteria,4NVXM@976|Bacteroidetes,1IMRR@117743|Flavobacteriia,2PBRZ@246874|Cryomorphaceae	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_2844301_9	755732.Fluta_2425	3.317e-62	222.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,1HX9E@117743|Flavobacteriia,2PAUH@246874|Cryomorphaceae	976|Bacteroidetes	M	NlpC/P60 family	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
TLS3_k127_2844301_12	1380600.AUYN01000003_gene72	4.415e-47	182.0	COG0451@1|root,COG0451@2|Bacteria,4NH7Y@976|Bacteroidetes,1I0N9@117743|Flavobacteriia	976|Bacteroidetes	M	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS3_k127_2844301_0	755732.Fluta_2426	1.529e-231	721.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,1HXUW@117743|Flavobacteriia,2PAA8@246874|Cryomorphaceae	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
TLS3_k127_2844301_13	1121007.AUML01000028_gene2122	1.257e-36	148.0	28MQX@1|root,2ZAZM@2|Bacteria,4NHM9@976|Bacteroidetes,1I1SR@117743|Flavobacteriia,2YJBN@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2844301_5	755732.Fluta_2417	1.312e-98	329.0	COG0300@1|root,COG0300@2|Bacteria,4NEMK@976|Bacteroidetes,1HZGI@117743|Flavobacteriia,2PAPR@246874|Cryomorphaceae	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_2844301_11	755732.Fluta_2419	1.544e-49	179.0	2A94W@1|root,30Y96@2|Bacteria,4PC0G@976|Bacteroidetes,1ICSA@117743|Flavobacteriia,2PBZB@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2844301_6	755732.Fluta_2420	5.74e-94	311.0	COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,1IAHR@117743|Flavobacteriia,2PB7S@246874|Cryomorphaceae	976|Bacteroidetes	G	SIS domain	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
TLS3_k127_2844301_14	755732.Fluta_2421	2.609e-30	124.0	COG4103@1|root,COG4103@2|Bacteria,4NNTQ@976|Bacteroidetes,1I292@117743|Flavobacteriia,2PC0V@246874|Cryomorphaceae	976|Bacteroidetes	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
TLS3_k127_2844301_7	755732.Fluta_2438	2.427e-81	273.0	COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,1I19U@117743|Flavobacteriia,2PAUM@246874|Cryomorphaceae	976|Bacteroidetes	L	Ferric uptake regulator family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
TLS3_k127_2844301_17	755732.Fluta_2439	1.402e-08	61.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	rsbV	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	HATPase_c_2,STAS,STAS_2
TLS3_k127_2860479_0	980584.AFPB01000147_gene1275	1.122e-243	778.0	COG3064@1|root,COG5412@1|root,COG3064@2|Bacteria,COG5412@2|Bacteria	2|Bacteria	N	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,SLT
TLS3_k127_2868298_0	755732.Fluta_2600	1.939e-143	465.0	COG1668@1|root,COG1668@2|Bacteria,4NMG0@976|Bacteroidetes,1I1TW@117743|Flavobacteriia,2PBGR@246874|Cryomorphaceae	976|Bacteroidetes	CP	ABC-2 family transporter protein	-	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3
TLS3_k127_2868298_1	755732.Fluta_2601	1.796e-96	318.0	COG4555@1|root,COG4555@2|Bacteria,4PNSV@976|Bacteroidetes,1IKBA@117743|Flavobacteriia,2PBF9@246874|Cryomorphaceae	976|Bacteroidetes	CP	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	-	ABC_tran
TLS3_k127_2872464_2	755732.Fluta_0301	1.556e-109	357.0	COG0524@1|root,COG0524@2|Bacteria,4NFJ9@976|Bacteroidetes,1HY55@117743|Flavobacteriia,2PAF2@246874|Cryomorphaceae	976|Bacteroidetes	G	pfkB family carbohydrate kinase	ydjH	-	-	-	-	-	-	-	-	-	-	-	PfkB
TLS3_k127_2872464_3	755732.Fluta_1098	2.037e-101	336.0	COG0596@1|root,COG0596@2|Bacteria,4NDZI@976|Bacteroidetes,1HXF6@117743|Flavobacteriia,2PAPJ@246874|Cryomorphaceae	976|Bacteroidetes	S	Serine aminopeptidase, S33	ybfF	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_2872464_5	1416760.AYMS01000051_gene290	1.308e-07	60.0	COG2608@1|root,COG2608@2|Bacteria,4NW6S@976|Bacteroidetes,1I600@117743|Flavobacteriia,47IFI@76831|Myroides	976|Bacteroidetes	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
TLS3_k127_2872464_4	755732.Fluta_2200	1.319e-98	324.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,1HXAB@117743|Flavobacteriia,2PAMR@246874|Cryomorphaceae	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
TLS3_k127_2872464_0	755732.Fluta_1993	2.223e-210	662.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1HYF1@117743|Flavobacteriia,2PA7E@246874|Cryomorphaceae	976|Bacteroidetes	P	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
TLS3_k127_2872464_1	755732.Fluta_1996	7.355e-167	527.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,1HX2K@117743|Flavobacteriia,2PAA2@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
TLS3_k127_2894328_0	1122176.KB903561_gene3582	1.59e-157	511.0	COG1409@1|root,COG4935@1|root,COG1409@2|Bacteria,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,1J10T@117747|Sphingobacteriia	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
TLS3_k127_2894328_1	1408473.JHXO01000007_gene721	2.155e-22	106.0	2E6TM@1|root,331DG@2|Bacteria,4NYW8@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
TLS3_k127_2929655_2	755732.Fluta_3562	8.186e-57	204.0	2BB8B@1|root,324R0@2|Bacteria,4NQG8@976|Bacteroidetes,1ICMZ@117743|Flavobacteriia,2PB21@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2929655_0	755732.Fluta_3563	1.036e-254	795.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,1HXK2@117743|Flavobacteriia,2PAJG@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
TLS3_k127_2929655_1	755732.Fluta_3566	1.102e-232	729.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1HYIP@117743|Flavobacteriia,2PBI8@246874|Cryomorphaceae	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2929655_3	1002367.HMPREF0673_01410	0.0001924	49.0	COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,4NEER@976|Bacteroidetes,2FM02@200643|Bacteroidia	976|Bacteroidetes	MNU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	lytG	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,LysM
TLS3_k127_2934626_1	1121889.AUDM01000041_gene884	1.6e-52	185.0	28JFC@1|root,2Z999@2|Bacteria,4NJ3R@976|Bacteroidetes,1HYQ0@117743|Flavobacteriia	976|Bacteroidetes	S	MvaI/BcnI restriction endonuclease family	-	-	-	-	-	-	-	-	-	-	-	-	MvaI_BcnI
TLS3_k127_2934626_3	880071.Fleli_3238	2.258e-43	159.0	COG1607@1|root,COG1607@2|Bacteria,4NMK1@976|Bacteroidetes,47N9Z@768503|Cytophagia	976|Bacteroidetes	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
TLS3_k127_2934626_4	1408473.JHXO01000001_gene2016	1.041e-40	174.0	COG4485@1|root,COG4485@2|Bacteria,4P3PY@976|Bacteroidetes	976|Bacteroidetes	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2934626_2	1131269.AQVV01000027_gene82	3.027e-44	170.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_2934626_0	755732.Fluta_1377	3.524e-85	299.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,1HY9S@117743|Flavobacteriia,2PABC@246874|Cryomorphaceae	976|Bacteroidetes	T	periplasmic ligand-binding sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
TLS3_k127_2936647_10	1410676.JNKL01000024_gene766	5.146e-05	53.0	COG0457@1|root,COG3118@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,1MVB8@1224|Proteobacteria,1RPSN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Cellulose synthase	bcsC	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	BCSC_C,TPR_16,TPR_19,TPR_8
TLS3_k127_2936647_8	1385510.N781_16000	2.11e-21	100.0	2DP6N@1|root,330S4@2|Bacteria,1V63A@1239|Firmicutes,4HICJ@91061|Bacilli	91061|Bacilli	S	SMI1 / KNR4 family	yokK	-	-	-	-	-	-	-	-	-	-	-	SUKH_6
TLS3_k127_2936647_11	118168.MC7420_3036	0.0002469	51.0	2CC9G@1|root,2ZER4@2|Bacteria,1GG3Y@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2936647_5	1229487.AMYW01000027_gene2785	3.432e-43	183.0	COG3210@1|root,COG3210@2|Bacteria,4PP9Z@976|Bacteroidetes	976|Bacteroidetes	U	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
TLS3_k127_2936647_2	714943.Mucpa_3173	3.686e-58	207.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1INNX@117747|Sphingobacteriia	976|Bacteroidetes	O	chelatase, subunit chli	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
TLS3_k127_2936647_0	349521.HCH_06395	4.217e-145	476.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,1RP3U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TLS3_k127_2936647_3	1250006.JHZZ01000001_gene1335	3.086e-54	194.0	2E9ZF@1|root,3344X@2|Bacteria,4P5G2@976|Bacteroidetes,1IA51@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2936647_1	1313421.JHBV01000139_gene1287	3.251e-64	230.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
TLS3_k127_2936647_7	1250006.JHZZ01000001_gene1342	1.359e-25	108.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_1,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
TLS3_k127_29611_6	402612.FP0232	0.0007961	44.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NMA6@976|Bacteroidetes,1IJ6Q@117743|Flavobacteriia,2P0JV@237|Flavobacterium	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Cleaved_Adhesin,Peptidase_M43
TLS3_k127_29611_3	1408433.JHXV01000006_gene2680	2.264e-87	299.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,1HYCJ@117743|Flavobacteriia,2PBM7@246874|Cryomorphaceae	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_29611_2	755732.Fluta_1659	6.018e-94	316.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,1HYNK@117743|Flavobacteriia,2PARH@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
TLS3_k127_29611_5	755732.Fluta_1660	8.207e-72	247.0	COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,1HXN2@117743|Flavobacteriia,2PASV@246874|Cryomorphaceae	976|Bacteroidetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
TLS3_k127_29611_4	755732.Fluta_1661	1.964e-81	276.0	COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes,1HYH0@117743|Flavobacteriia,2PAQT@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
TLS3_k127_29611_0	755732.Fluta_1340	1.648e-127	409.0	COG2057@1|root,COG2057@2|Bacteria,4NG9J@976|Bacteroidetes,1HWRK@117743|Flavobacteriia,2PAD8@246874|Cryomorphaceae	976|Bacteroidetes	I	Coenzyme A transferase	scoB	-	2.8.3.5,2.8.3.6	ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
TLS3_k127_29611_1	755732.Fluta_1341	5.297e-95	332.0	COG1807@1|root,COG1807@2|Bacteria,4NXNF@976|Bacteroidetes,1IMQ5@117743|Flavobacteriia,2PB6F@246874|Cryomorphaceae	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2971399_5	1121859.KB890750_gene514	5.466e-05	56.0	arCOG06169@1|root,2ZXVP@2|Bacteria,4NNWP@976|Bacteroidetes	976|Bacteroidetes	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
TLS3_k127_2971399_0	1506583.JQJY01000004_gene2829	5.756e-108	359.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,1HZDH@117743|Flavobacteriia,2NVMW@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
TLS3_k127_2971399_4	272134.KB731324_gene6057	3.211e-13	83.0	COG1520@1|root,COG1520@2|Bacteria,1GDEQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
TLS3_k127_2971399_3	1120951.AUBG01000005_gene2096	9.746e-14	84.0	COG1404@1|root,COG2866@1|root,COG5492@1|root,COG1404@2|Bacteria,COG2866@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	xynX1	-	3.2.1.99	ko:K06113,ko:K12685	-	-	-	-	ko00000,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	GH43	-	Big_2,Cu_amine_oxidN1,F5_F8_type_C,Peptidase_S8,SLH
TLS3_k127_2971399_2	1408473.JHXO01000001_gene2321	3.178e-14	86.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4PBWR@976|Bacteroidetes,2FZMI@200643|Bacteroidia	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
TLS3_k127_2971399_1	1237149.C900_03820	7.329e-37	147.0	COG0859@1|root,COG0859@2|Bacteria,4P2TG@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
TLS3_k127_2978065_2	929704.Myrod_0478	4.723e-22	104.0	COG2227@1|root,COG2227@2|Bacteria,4NF6D@976|Bacteroidetes,1HXVW@117743|Flavobacteriia,47IPH@76831|Myroides	976|Bacteroidetes	H	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
TLS3_k127_2978065_1	755732.Fluta_0112	1.658e-50	194.0	COG5295@1|root,COG5295@2|Bacteria,4NR12@976|Bacteroidetes,1IIJ9@117743|Flavobacteriia	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2978065_10	1137281.D778_02465	0.0004838	53.0	COG1470@1|root,COG4625@1|root,COG1470@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Calx-beta,CarboxypepD_reg,DUF11,HYR,PATR,PKD,SLH,SdrD_B,fn3
TLS3_k127_2978065_0	755732.Fluta_1367	5.693e-81	276.0	COG4935@1|root,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,1HYKE@117743|Flavobacteriia,2PBFE@246874|Cryomorphaceae	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
TLS3_k127_2978382_0	1296415.JACC01000030_gene2777	2.349e-74	284.0	COG2351@1|root,COG3409@1|root,COG2351@2|Bacteria,COG3409@2|Bacteria,4NJ4W@976|Bacteroidetes	976|Bacteroidetes	M	Salmonella virulence plasmid 28.1kDa A protein	-	-	-	-	-	-	-	-	-	-	-	-	Hemopexin,VRP1
TLS3_k127_3002216_0	755732.Fluta_3416	5.444e-241	751.0	COG1061@1|root,COG1061@2|Bacteria,4NECV@976|Bacteroidetes,1HWX1@117743|Flavobacteriia,2PBJQ@246874|Cryomorphaceae	976|Bacteroidetes	L	helicase superfamily c-terminal domain	res	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
TLS3_k127_3002216_1	755732.Fluta_4059	6.572e-35	143.0	COG2006@1|root,COG2006@2|Bacteria,4PHHF@976|Bacteroidetes,1ICS8@117743|Flavobacteriia,2PBZ7@246874|Cryomorphaceae	976|Bacteroidetes	S	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3009403_1	1202532.FF52_03030	4.908e-72	245.0	COG3832@1|root,COG3832@2|Bacteria,4NRH6@976|Bacteroidetes,1ICQE@117743|Flavobacteriia,2NU82@237|Flavobacterium	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_3009403_2	1121373.KB903635_gene843	1.417e-60	211.0	COG4898@1|root,COG4898@2|Bacteria,4NQGY@976|Bacteroidetes,47RED@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_3009403_0	1121373.KB903654_gene1676	9.093e-88	294.0	COG3448@1|root,COG3448@2|Bacteria,4NMHI@976|Bacteroidetes,47P6M@768503|Cytophagia	976|Bacteroidetes	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
TLS3_k127_3009403_3	926562.Oweho_2299	3.495e-55	199.0	29VE2@1|root,30GUS@2|Bacteria,4NP29@976|Bacteroidetes,1I29M@117743|Flavobacteriia,2PBUQ@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_301505_9	226186.BT_1608	3.039e-95	329.0	COG2843@1|root,COG2843@2|Bacteria,4NGD2@976|Bacteroidetes,2FQ0M@200643|Bacteroidia,4AMPS@815|Bacteroidaceae	976|Bacteroidetes	M	Bacterial capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
TLS3_k127_301505_12	755732.Fluta_0816	2.067e-65	227.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,1I272@117743|Flavobacteriia,2PB13@246874|Cryomorphaceae	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
TLS3_k127_301505_0	755732.Fluta_0815	0.0	1043.0	COG0550@1|root,COG0550@2|Bacteria,4NE6R@976|Bacteroidetes,1HWYU@117743|Flavobacteriia,2PAJJ@246874|Cryomorphaceae	976|Bacteroidetes	L	TIGRFAM DNA topoisomerase III, bacteria and conjugative plasmid	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
TLS3_k127_301505_14	1408433.JHXV01000038_gene2195	9.782e-55	203.0	2EAQY@1|root,334T6@2|Bacteria,4P25X@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_301505_13	877455.Metbo_0757	2.392e-60	228.0	COG0784@1|root,arCOG02348@1|root,arCOG06712@1|root,arCOG02348@2157|Archaea,arCOG02393@2157|Archaea,arCOG06712@2157|Archaea	2157|Archaea	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_301505_10	1122176.KB903544_gene810	2.856e-68	237.0	COG2824@1|root,COG2824@2|Bacteria,4NEFZ@976|Bacteroidetes,1IT0X@117747|Sphingobacteriia	976|Bacteroidetes	P	PhnA domain	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
TLS3_k127_301505_2	755732.Fluta_2100	5.97e-215	676.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1HXGD@117743|Flavobacteriia,2PAHD@246874|Cryomorphaceae	976|Bacteroidetes	F	PFAM AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
TLS3_k127_301505_3	755732.Fluta_2101	8.956e-183	576.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,1HYAP@117743|Flavobacteriia,2PAHC@246874|Cryomorphaceae	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TLS3_k127_301505_5	755732.Fluta_2106	6.034e-137	439.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,1HX31@117743|Flavobacteriia,2PAIF@246874|Cryomorphaceae	976|Bacteroidetes	F	TIGRFAM Orotidine 5'-phosphate decarboxylase, subfamily 2	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
TLS3_k127_301505_1	755732.Fluta_0900	8.708e-297	935.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1HYND@117743|Flavobacteriia,2PA5Y@246874|Cryomorphaceae	976|Bacteroidetes	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
TLS3_k127_301505_4	755732.Fluta_0901	1.637e-153	489.0	COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,1HWWH@117743|Flavobacteriia,2PAM5@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
TLS3_k127_301505_8	1004149.AFOE01000029_gene2805	1.096e-97	328.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1HWSU@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
TLS3_k127_301505_15	1122605.KB893646_gene8	4.352e-44	167.0	COG1595@1|root,COG1595@2|Bacteria,4NQTP@976|Bacteroidetes,1ITCU@117747|Sphingobacteriia	976|Bacteroidetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_301505_16	760192.Halhy_5317	1.665e-27	119.0	2DNNM@1|root,32YAS@2|Bacteria,4NVE7@976|Bacteroidetes,1IZ48@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_301505_7	760192.Halhy_5318	1.162e-113	376.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1IW4H@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
TLS3_k127_301505_6	1484460.JSWG01000008_gene1892	2.589e-132	441.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HZIA@117743|Flavobacteriia	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
TLS3_k127_301505_17	1122176.KB903560_gene3531	2.134e-19	102.0	COG4319@1|root,COG4319@2|Bacteria,4NTMK@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
TLS3_k127_301505_11	1237149.C900_00560	1.381e-65	241.0	COG0726@1|root,COG0726@2|Bacteria,4NKYS@976|Bacteroidetes,47NF6@768503|Cytophagia	976|Bacteroidetes	G	PFAM Polysaccharide deacetylase	pgdA	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
TLS3_k127_301505_18	926562.Oweho_0115	3.79e-10	63.0	COG4743@1|root,COG4743@2|Bacteria,4NU7A@976|Bacteroidetes,1I314@117743|Flavobacteriia,2PB9G@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1616)	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3047003_3	1408433.JHXV01000037_gene2548	6.558e-64	229.0	COG0248@1|root,COG0248@2|Bacteria,4NH03@976|Bacteroidetes,1IMPX@117743|Flavobacteriia,2PAVM@246874|Cryomorphaceae	976|Bacteroidetes	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
TLS3_k127_3047003_0	755732.Fluta_0232	6.112e-160	515.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,1HXQA@117743|Flavobacteriia,2PAWK@246874|Cryomorphaceae	976|Bacteroidetes	CP	ABC-2 family transporter protein	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
TLS3_k127_3047003_2	755732.Fluta_0233	2.071e-139	449.0	COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,1HXY0@117743|Flavobacteriia,2PAMV@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4162)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
TLS3_k127_3047003_1	1215092.PA6_060_00020	2.484e-145	469.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,1RPZX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Radical SAM	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
TLS3_k127_3072735_2	1313421.JHBV01000028_gene1857	1.122e-88	315.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
TLS3_k127_3072735_3	1121286.AUMT01000012_gene2857	7.281e-46	186.0	COG3291@1|root,COG3291@2|Bacteria,4NMVW@976|Bacteroidetes,1I1JQ@117743|Flavobacteriia	976|Bacteroidetes	G	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_3072735_0	487796.Flav2ADRAFT_0676	5.198e-190	596.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1HXQG@117743|Flavobacteriia	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
TLS3_k127_3072735_1	487796.Flav2ADRAFT_0677	5.26e-136	437.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,1HYIB@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS3_k127_3072735_4	1122176.KB903576_gene5022	1.242e-15	76.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,1IQUN@117747|Sphingobacteriia	976|Bacteroidetes	E	decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS3_k127_3075239_3	1353276.JADR01000005_gene2417	2.867e-14	76.0	COG1765@1|root,COG1765@2|Bacteria,4NNZ6@976|Bacteroidetes,1I2C1@117743|Flavobacteriia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
TLS3_k127_3075239_4	81824.XP_001749680.1	1.53e-10	74.0	KOG0583@1|root,KOG0583@2759|Eukaryota	2759|Eukaryota	G	protein serine/threonine kinase activity	CHK1	GO:0002831,GO:0002833,GO:0007162,GO:0008150,GO:0009272,GO:0009405,GO:0009607,GO:0009987,GO:0010033,GO:0010570,GO:0022407,GO:0022408,GO:0030100,GO:0030155,GO:0030447,GO:0032879,GO:0033993,GO:0036180,GO:0040007,GO:0040008,GO:0042221,GO:0042546,GO:0042710,GO:0043900,GO:0044010,GO:0044011,GO:0044085,GO:0044182,GO:0044419,GO:0044764,GO:0045806,GO:0045927,GO:0046677,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048584,GO:0050764,GO:0050765,GO:0050789,GO:0050794,GO:0050896,GO:0051040,GO:0051042,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051703,GO:0051704,GO:0051716,GO:0060627,GO:0065007,GO:0070887,GO:0071236,GO:0071310,GO:0071396,GO:0071554,GO:0071840,GO:0071852,GO:0090033,GO:0090605,GO:0090609,GO:0097305,GO:0097306,GO:0097307,GO:0097308,GO:1900190,GO:1900231,GO:1900428,GO:1900430,GO:1900443,GO:1900445,GO:1901700,GO:1901701	2.7.11.1,2.7.13.3	ko:K13412,ko:K14005,ko:K19690	ko02020,ko04141,ko04626,ko05145,map02020,map04141,map04626,map05145	M00404,M00516	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko04131	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg,TPR_8
TLS3_k127_3075239_1	1144313.PMI10_00422	8.124e-82	279.0	COG3279@1|root,COG3279@2|Bacteria,4NKKW@976|Bacteroidetes,1I0TJ@117743|Flavobacteriia,2NT7I@237|Flavobacterium	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_3075239_0	991.IW20_04580	5.471e-172	557.0	COG0457@1|root,COG5002@1|root,COG0457@2|Bacteria,COG5002@2|Bacteria,4NI29@976|Bacteroidetes,1HX1A@117743|Flavobacteriia,2NSNR@237|Flavobacterium	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_10,TPR_12,TPR_8
TLS3_k127_3075239_2	1202532.FF52_22404	4.861e-56	198.0	COG4630@1|root,COG4631@1|root,COG4630@2|Bacteria,COG4631@2|Bacteria,4PMEG@976|Bacteroidetes,1IJWR@117743|Flavobacteriia	976|Bacteroidetes	F	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
TLS3_k127_3090385_14	755732.Fluta_0759	1.891e-10	61.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,1HWR7@117743|Flavobacteriia,2PA4H@246874|Cryomorphaceae	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
TLS3_k127_3090385_9	755732.Fluta_0758	1.26e-37	141.0	COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,1I3WQ@117743|Flavobacteriia,2PB2F@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
TLS3_k127_3090385_13	869213.JCM21142_31269	5.085e-14	72.0	COG0257@1|root,COG0257@2|Bacteria,4NXGE@976|Bacteroidetes,47SMT@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
TLS3_k127_3090385_8	755732.Fluta_0756	1.409e-57	202.0	COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,1I1ZW@117743|Flavobacteriia,2PAXV@246874|Cryomorphaceae	976|Bacteroidetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
TLS3_k127_3090385_6	755732.Fluta_0755	1.803e-69	236.0	COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,1I1GI@117743|Flavobacteriia,2PAR0@246874|Cryomorphaceae	976|Bacteroidetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
TLS3_k127_3090385_4	1408433.JHXV01000034_gene47	3.728e-106	346.0	COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,1HWWF@117743|Flavobacteriia,2PACT@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
TLS3_k127_3090385_1	755732.Fluta_0753	4.765e-191	599.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,1HX6J@117743|Flavobacteriia,2PA8U@246874|Cryomorphaceae	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
TLS3_k127_3090385_7	1408433.JHXV01000034_gene49	1.914e-66	232.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,1I1B5@117743|Flavobacteriia,2PASX@246874|Cryomorphaceae	976|Bacteroidetes	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
TLS3_k127_3090385_10	1313421.JHBV01000004_gene763	4.891e-31	140.0	COG4935@1|root,COG4935@2|Bacteria,4NT9V@976|Bacteroidetes,1IYMI@117747|Sphingobacteriia	976|Bacteroidetes	O	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3090385_12	1313421.JHBV01000004_gene779	3.06e-16	93.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,CHU_C,Gram_pos_anchor,SprB
TLS3_k127_3090385_2	755732.Fluta_0751	1.136e-178	565.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,1HXZ3@117743|Flavobacteriia,2PAK9@246874|Cryomorphaceae	976|Bacteroidetes	F	PFAM Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
TLS3_k127_3090385_0	755732.Fluta_0750	9.924e-229	713.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,1HWRR@117743|Flavobacteriia,2PAAC@246874|Cryomorphaceae	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
TLS3_k127_3090385_15	7739.XP_002597264.1	6.99e-07	63.0	28K45@1|root,2QSIP@2759|Eukaryota,38E3S@33154|Opisthokonta,3BBJ0@33208|Metazoa,3CSD9@33213|Bilateria,4896I@7711|Chordata	33208|Metazoa	T	positive regulation of lateral motor column neuron migration	RELN	GO:0000902,GO:0000904,GO:0001101,GO:0001764,GO:0001932,GO:0001934,GO:0001941,GO:0003002,GO:0003008,GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006935,GO:0006950,GO:0006996,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007389,GO:0007399,GO:0007409,GO:0007411,GO:0007416,GO:0007417,GO:0007420,GO:0007494,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007616,GO:0007626,GO:0008104,GO:0008150,GO:0008152,GO:0008306,GO:0008347,GO:0009410,GO:0009605,GO:0009611,GO:0009612,GO:0009628,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009889,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010001,GO:0010033,GO:0010035,GO:0010038,GO:0010226,GO:0010243,GO:0010468,GO:0010469,GO:0010556,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010720,GO:0010769,GO:0010770,GO:0010975,GO:0010976,GO:0014066,GO:0014068,GO:0014070,GO:0016043,GO:0016310,GO:0016358,GO:0016477,GO:0017085,GO:0018108,GO:0018193,GO:0018212,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0021510,GO:0021511,GO:0021517,GO:0021536,GO:0021537,GO:0021542,GO:0021543,GO:0021761,GO:0021766,GO:0021769,GO:0021795,GO:0021799,GO:0021800,GO:0021801,GO:0021819,GO:0021854,GO:0021885,GO:0021987,GO:0022008,GO:0022029,GO:0022030,GO:0022603,GO:0022604,GO:0022607,GO:0022898,GO:0023051,GO:0023052,GO:0023056,GO:0030030,GO:0030154,GO:0030182,GO:0030334,GO:0030335,GO:0030424,GO:0030425,GO:0030900,GO:0031012,GO:0031175,GO:0031323,GO:0031325,GO:0031326,GO:0031344,GO:0031346,GO:0031399,GO:0031401,GO:0031503,GO:0031644,GO:0031646,GO:0031960,GO:0032006,GO:0032008,GO:0032268,GO:0032270,GO:0032409,GO:0032411,GO:0032412,GO:0032414,GO:0032501,GO:0032502,GO:0032570,GO:0032793,GO:0032870,GO:0032879,GO:0032989,GO:0032990,GO:0033036,GO:0033555,GO:0033674,GO:0033993,GO:0034613,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0035176,GO:0035295,GO:0035418,GO:0035690,GO:0036211,GO:0036477,GO:0038026,GO:0040011,GO:0040012,GO:0040017,GO:0042063,GO:0042221,GO:0042325,GO:0042327,GO:0042330,GO:0042391,GO:0042493,GO:0042995,GO:0043005,GO:0043025,GO:0043085,GO:0043113,GO:0043170,GO:0043200,GO:0043204,GO:0043269,GO:0043270,GO:0043412,GO:0043549,GO:0044057,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044297,GO:0044421,GO:0044424,GO:0044463,GO:0044464,GO:0045471,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045859,GO:0045860,GO:0045937,GO:0046677,GO:0048167,GO:0048265,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048565,GO:0048583,GO:0048584,GO:0048646,GO:0048666,GO:0048667,GO:0048678,GO:0048699,GO:0048731,GO:0048812,GO:0048814,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050730,GO:0050731,GO:0050767,GO:0050769,GO:0050773,GO:0050775,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050795,GO:0050803,GO:0050804,GO:0050806,GO:0050807,GO:0050808,GO:0050877,GO:0050890,GO:0050896,GO:0051049,GO:0051050,GO:0051056,GO:0051057,GO:0051090,GO:0051091,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051252,GO:0051270,GO:0051272,GO:0051338,GO:0051347,GO:0051384,GO:0051385,GO:0051412,GO:0051602,GO:0051641,GO:0051668,GO:0051674,GO:0051703,GO:0051704,GO:0051705,GO:0051716,GO:0051960,GO:0051962,GO:0051966,GO:0051968,GO:0055123,GO:0060255,GO:0060284,GO:0060291,GO:0060322,GO:0060998,GO:0060999,GO:0061001,GO:0061003,GO:0061024,GO:0061097,GO:0061098,GO:0061564,GO:0065007,GO:0065008,GO:0065009,GO:0070325,GO:0070326,GO:0070542,GO:0070727,GO:0070887,GO:0070925,GO:0071310,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072578,GO:0072657,GO:0080090,GO:0090128,GO:0090129,GO:0097106,GO:0097107,GO:0097114,GO:0097119,GO:0097120,GO:0097305,GO:0097327,GO:0097447,GO:0097458,GO:0097475,GO:0097476,GO:0097477,GO:0097485,GO:0098698,GO:0098815,GO:0099068,GO:0099084,GO:0099173,GO:0099175,GO:0099177,GO:0099601,GO:0120025,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:1900006,GO:1900271,GO:1900273,GO:1900449,GO:1900451,GO:1901564,GO:1901654,GO:1901655,GO:1901698,GO:1901700,GO:1901701,GO:1902076,GO:1902078,GO:1902531,GO:1902533,GO:1903506,GO:1904062,GO:1904064,GO:1904861,GO:1905483,GO:1905485,GO:2000026,GO:2000112,GO:2000145,GO:2000147,GO:2000273,GO:2000310,GO:2000311,GO:2000463,GO:2000969,GO:2001141,GO:2001222,GO:2001224,GO:2001257,GO:2001259	-	ko:K06249	ko04151,ko04510,ko04512,ko05165,map04151,map04510,map04512,map05165	-	-	-	ko00000,ko00001,ko01000,ko04516	-	-	-	EGF_2,Reeler
TLS3_k127_3090385_3	755732.Fluta_0748	6.714e-167	556.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_3090385_16	568076.XP_007822970.1	1.126e-05	58.0	2CKY2@1|root,2S3WN@2759|Eukaryota,3A5TN@33154|Opisthokonta,3P543@4751|Fungi,3RJAN@4890|Ascomycota,21Q5Q@147550|Sordariomycetes,3TN7W@5125|Hypocreales,3G70K@34397|Clavicipitaceae	4751|Fungi	S	Cell surface spherulin 4-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Spherulin4
TLS3_k127_3090385_11	869213.JCM21142_83275	1.349e-25	123.0	COG1345@1|root,COG1520@1|root,COG3291@1|root,COG1345@2|Bacteria,COG1520@2|Bacteria,COG3291@2|Bacteria,4NJRF@976|Bacteroidetes,47PMY@768503|Cytophagia	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_3117682_2	1492737.FEM08_14410	6.352e-14	76.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,1I2TQ@117743|Flavobacteriia,2NWRF@237|Flavobacterium	976|Bacteroidetes	K	ArsR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
TLS3_k127_3117682_0	755732.Fluta_2193	6.096e-181	573.0	COG0399@1|root,COG0399@2|Bacteria,4NFQ8@976|Bacteroidetes,1HZBY@117743|Flavobacteriia,2PBDW@246874|Cryomorphaceae	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_3117682_1	485918.Cpin_4757	5.737e-87	292.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,1IR9A@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
TLS3_k127_3133730_0	755732.Fluta_3444	6.615e-219	691.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,1HX3E@117743|Flavobacteriia,2PBJM@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Peptidase family M13	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
TLS3_k127_3133730_1	755732.Fluta_3441	1.422e-165	545.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1HWXR@117743|Flavobacteriia,2PA52@246874|Cryomorphaceae	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3133730_4	1382315.JPOI01000001_gene1370	3.318e-60	212.0	COG1247@1|root,COG1247@2|Bacteria,1V3V3@1239|Firmicutes,4HHNY@91061|Bacilli,1WE8Z@129337|Geobacillus	91061|Bacilli	M	Acetyltransferase (GNAT) domain	ywnH	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_4
TLS3_k127_3133730_3	1242864.D187_000766	4.69e-66	233.0	COG2249@1|root,COG2249@2|Bacteria,1MXFT@1224|Proteobacteria,42TEF@68525|delta/epsilon subdivisions,2WPFC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Flavodoxin-like fold	-	-	1.6.5.2	ko:K00355,ko:K11748	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000,ko02000	2.A.37.1.2	-	-	Flavodoxin_2
TLS3_k127_3133730_5	1122605.KB893627_gene3015	3.097e-27	119.0	2DE9F@1|root,2ZM2T@2|Bacteria,4P7F1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3133730_2	755732.Fluta_3440	4.555e-99	328.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1HY5S@117743|Flavobacteriia,2PAT9@246874|Cryomorphaceae	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
TLS3_k127_3139899_1	1408433.JHXV01000025_gene4044	4.698e-58	214.0	COG1538@1|root,COG1538@2|Bacteria,4NEH3@976|Bacteroidetes,1HXJ9@117743|Flavobacteriia,2PBC1@246874|Cryomorphaceae	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_3139899_0	1408433.JHXV01000028_gene2155	0.0	1041.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,1HYJ3@117743|Flavobacteriia,2PAHE@246874|Cryomorphaceae	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
TLS3_k127_3139899_3	1121896.JMLU01000006_gene28	6.96e-19	93.0	2E09A@1|root,32VWX@2|Bacteria,4NT9W@976|Bacteroidetes,1I9TI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3139899_2	1313421.JHBV01000046_gene296	1.352e-42	173.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Peptidase_M28
TLS3_k127_3161884_0	1121887.AUDK01000002_gene2039	1.769e-153	495.0	COG0665@1|root,COG0665@2|Bacteria,4NEUE@976|Bacteroidetes,1HYMG@117743|Flavobacteriia,2NTQY@237|Flavobacterium	976|Bacteroidetes	E	FAD dependent oxidoreductase	dadA	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
TLS3_k127_3161884_1	1267211.KI669560_gene447	2.161e-73	248.0	COG3938@1|root,COG3938@2|Bacteria,4NHJZ@976|Bacteroidetes,1INXZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the proline racemase family	-	-	5.1.1.8	ko:K12658	ko00330,map00330	-	R03296	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
TLS3_k127_316262_1	1408433.JHXV01000031_gene3251	6.801e-106	365.0	COG1629@1|root,COG1629@2|Bacteria,4P929@976|Bacteroidetes,1IB8G@117743|Flavobacteriia	976|Bacteroidetes	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_316262_2	1121904.ARBP01000010_gene2339	2.085e-32	126.0	COG3369@1|root,COG3369@2|Bacteria,4NW9E@976|Bacteroidetes,47W0Y@768503|Cytophagia	976|Bacteroidetes	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
TLS3_k127_316262_0	755732.Fluta_3805	5.862e-124	413.0	COG2133@1|root,COG2133@2|Bacteria,4NH6T@976|Bacteroidetes,1I1U0@117743|Flavobacteriia,2PBYX@246874|Cryomorphaceae	976|Bacteroidetes	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,GSDH
TLS3_k127_3195482_0	866536.Belba_1269	0.0	1305.0	COG1538@1|root,COG3696@1|root,COG1538@2|Bacteria,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,47JC4@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
TLS3_k127_3223156_0	755732.Fluta_0821	1.509e-170	546.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,1HZ71@117743|Flavobacteriia,2PBGE@246874|Cryomorphaceae	976|Bacteroidetes	T	GHKL domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_3223156_1	755732.Fluta_0828	2.193e-131	421.0	COG0492@1|root,COG0492@2|Bacteria,4NEQM@976|Bacteroidetes,1HWUC@117743|Flavobacteriia,2PBCP@246874|Cryomorphaceae	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_3263189_3	755732.Fluta_1070	2.068e-37	142.0	COG0328@1|root,COG0328@2|Bacteria,4NNQX@976|Bacteroidetes,1I1AV@117743|Flavobacteriia,2PBW8@246874|Cryomorphaceae	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
TLS3_k127_3263189_2	1408433.JHXV01000036_gene261	4.288e-40	156.0	COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,1I0I9@117743|Flavobacteriia,2PBX4@246874|Cryomorphaceae	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_3263189_0	1408433.JHXV01000036_gene262	1.333e-89	311.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1HYW1@117743|Flavobacteriia,2PBPR@246874|Cryomorphaceae	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_3263189_1	1408433.JHXV01000036_gene263	5.543e-75	265.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1HXW9@117743|Flavobacteriia,2PBTI@246874|Cryomorphaceae	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
TLS3_k127_3263189_4	1408433.JHXV01000036_gene264	1.552e-31	125.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,2PBB4@246874|Cryomorphaceae	976|Bacteroidetes	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS3_k127_3268691_7	755732.Fluta_0171	1.135e-26	119.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
TLS3_k127_3268691_6	755732.Fluta_0170	5.922e-49	189.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,1HXPD@117743|Flavobacteriia,2PBYZ@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_3268691_8	1124780.ANNU01000064_gene450	8.613e-23	115.0	COG3291@1|root,COG3291@2|Bacteria,4PHTU@976|Bacteroidetes,47P4N@768503|Cytophagia	976|Bacteroidetes	E	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_3268691_3	1223410.KN050846_gene2460	1.011e-76	289.0	COG2304@1|root,COG2911@1|root,COG2304@2|Bacteria,COG2911@2|Bacteria,4PKD0@976|Bacteroidetes,1HWKJ@117743|Flavobacteriia	976|Bacteroidetes	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,LRR_adjacent
TLS3_k127_3268691_11	1506583.JQJY01000004_gene2496	2.759e-05	58.0	COG1361@1|root,COG3291@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,4NDZC@976|Bacteroidetes,1I0G4@117743|Flavobacteriia,2NT7Y@237|Flavobacterium	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
TLS3_k127_3268691_0	755732.Fluta_0701	0.0	1490.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3268691_4	755732.Fluta_0165	8.059e-57	202.0	COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,1I1XK@117743|Flavobacteriia,2PB63@246874|Cryomorphaceae	976|Bacteroidetes	L	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
TLS3_k127_3268691_2	1408433.JHXV01000015_gene1787	9.482e-142	454.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,1HWZA@117743|Flavobacteriia,2PA79@246874|Cryomorphaceae	976|Bacteroidetes	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
TLS3_k127_3268691_1	755732.Fluta_0357	5.211e-186	591.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,1HX7I@117743|Flavobacteriia,2PABE@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Bacterial trigger factor protein (TF)	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
TLS3_k127_3268691_5	266748.HY04_03650	5.735e-53	197.0	COG1073@1|root,COG1073@2|Bacteria,4NMQ5@976|Bacteroidetes,1I1PU@117743|Flavobacteriia,3ZQYG@59732|Chryseobacterium	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
TLS3_k127_3268691_9	408672.NBCG_02863	6.597e-08	63.0	COG0584@1|root,COG0584@2|Bacteria,2GJ5W@201174|Actinobacteria,4DQB5@85009|Propionibacteriales	201174|Actinobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ2	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
TLS3_k127_3272398_1	1408433.JHXV01000009_gene1251	3.224e-46	176.0	COG0642@1|root,COG2205@2|Bacteria,4NFEF@976|Bacteroidetes,1HXAX@117743|Flavobacteriia,2PBD9@246874|Cryomorphaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
TLS3_k127_3272398_0	1408433.JHXV01000009_gene1252	2.542e-188	597.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1I0DG@117743|Flavobacteriia,2PBBR@246874|Cryomorphaceae	976|Bacteroidetes	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
TLS3_k127_3272398_4	1237149.C900_05459	8.599e-10	68.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	2.7.13.3	ko:K13587	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
TLS3_k127_3272398_3	700598.Niako_2578	2.07e-23	106.0	COG3637@1|root,COG3637@2|Bacteria,4NNFR@976|Bacteroidetes,1IU44@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3272398_2	755732.Fluta_1564	2.021e-44	167.0	2DKFZ@1|root,309D6@2|Bacteria,4PK7J@976|Bacteroidetes,1IFCY@117743|Flavobacteriia,2PB0S@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
TLS3_k127_3273909_2	755732.Fluta_2902	8.398e-176	557.0	COG0277@1|root,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1HXIK@117743|Flavobacteriia,2PB4N@246874|Cryomorphaceae	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
TLS3_k127_3273909_12	755732.Fluta_2780	1.199e-66	232.0	2CGY7@1|root,2ZGS8@2|Bacteria,4NREX@976|Bacteroidetes,1ICQP@117743|Flavobacteriia,2PBSN@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4924
TLS3_k127_3273909_18	755732.Fluta_2779	1.292e-26	117.0	COG2825@1|root,COG2825@2|Bacteria	2|Bacteria	M	unfolded protein binding	-	-	1.14.19.1,2.1.1.80,3.1.1.61	ko:K00507,ko:K06142,ko:K13924	ko01040,ko01212,ko02020,ko02030,ko03320,ko04152,ko04212,map01040,map01212,map02020,map02030,map03320,map04152,map04212	M00506	R02222	RC00917	ko00000,ko00001,ko00002,ko01000,ko01004,ko02022,ko02035	-	-	-	DUF1640,DUF4164,OmpH,Y_Y_Y
TLS3_k127_3273909_15	755732.Fluta_2777	1.535e-48	176.0	2B04B@1|root,31SER@2|Bacteria,4PJPW@976|Bacteroidetes,1ICRV@117743|Flavobacteriia,2PBXJ@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
TLS3_k127_3273909_17	755732.Fluta_2776	2.821e-33	139.0	COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,1HXM2@117743|Flavobacteriia,2PB9S@246874|Cryomorphaceae	976|Bacteroidetes	G	PFAM BadF BadG BcrA BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
TLS3_k127_3273909_13	755732.Fluta_2771	7.982e-65	234.0	COG0515@1|root,COG0515@2|Bacteria	755732.Fluta_2771|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3273909_9	742767.HMPREF9456_01660	3.252e-74	254.0	COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,2FN7E@200643|Bacteroidia,22XSZ@171551|Porphyromonadaceae	976|Bacteroidetes	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
TLS3_k127_3273909_19	331678.Cphamn1_1085	3.807e-24	107.0	2E3G3@1|root,32YEY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3273909_8	755732.Fluta_2768	2.746e-104	342.0	COG0663@1|root,COG0663@2|Bacteria,4NG5P@976|Bacteroidetes,1HXXJ@117743|Flavobacteriia,2PAN1@246874|Cryomorphaceae	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	paaY	-	-	ko:K02617,ko:K08279	-	-	-	-	ko00000	-	-	-	Hexapep
TLS3_k127_3273909_21	1270193.JARP01000007_gene91	8.089e-24	104.0	2CENM@1|root,32S06@2|Bacteria,4NVR4@976|Bacteroidetes,1I5EG@117743|Flavobacteriia,2NX6R@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3273909_1	1237149.C900_01867	6.906e-204	644.0	COG2268@1|root,COG2268@2|Bacteria,4NIH3@976|Bacteroidetes,47TCM@768503|Cytophagia	976|Bacteroidetes	S	prohibitin homologues	yqiK	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
TLS3_k127_3273909_14	867900.Celly_1034	3.7e-52	190.0	29F7N@1|root,3025B@2|Bacteria,4NNR8@976|Bacteroidetes,1I26I@117743|Flavobacteriia,1F96V@104264|Cellulophaga	976|Bacteroidetes	S	serine protease	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
TLS3_k127_3273909_7	755732.Fluta_0647	5.448e-107	357.0	COG0682@1|root,COG0682@2|Bacteria,4NFP7@976|Bacteroidetes,1HYU8@117743|Flavobacteriia,2PAWS@246874|Cryomorphaceae	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
TLS3_k127_3273909_16	1048983.EL17_17430	2.38e-40	156.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,47MQZ@768503|Cytophagia	976|Bacteroidetes	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_3273909_3	755732.Fluta_2502	1.325e-154	502.0	2C5KB@1|root,2ZCDW@2|Bacteria,4NMNY@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3273909_4	866536.Belba_0068	1.142e-125	407.0	COG0428@1|root,COG0428@2|Bacteria,4NGQ8@976|Bacteroidetes,47NUB@768503|Cytophagia	976|Bacteroidetes	P	PFAM ZIP Zinc transporter	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
TLS3_k127_3273909_10	755732.Fluta_2496	4.792e-70	239.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,1I1AD@117743|Flavobacteriia,2PAWI@246874|Cryomorphaceae	976|Bacteroidetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
TLS3_k127_3273909_0	755732.Fluta_3136	2.28e-206	649.0	COG2195@1|root,COG2195@2|Bacteria,4NE7N@976|Bacteroidetes,1HWV8@117743|Flavobacteriia,2PBK7@246874|Cryomorphaceae	976|Bacteroidetes	E	Peptidase dimerisation domain	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_3273909_5	755732.Fluta_0524	3.745e-112	372.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1HXIE@117743|Flavobacteriia,2PANM@246874|Cryomorphaceae	976|Bacteroidetes	L	PFAM DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
TLS3_k127_3273909_11	1121957.ATVL01000009_gene1252	1.165e-66	235.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,47PRE@768503|Cytophagia	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
TLS3_k127_3273909_6	755732.Fluta_0522	5.221e-112	365.0	COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,1HXQK@117743|Flavobacteriia,2PANU@246874|Cryomorphaceae	976|Bacteroidetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
TLS3_k127_3273909_24	5722.XP_001328189.1	4.577e-05	51.0	COG0666@1|root,KOG4177@2759|Eukaryota	2759|Eukaryota	I	spectrin binding	-	-	-	ko:K15502,ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,DUF3447
TLS3_k127_3275943_2	755732.Fluta_0506	9.791e-41	161.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWKQ@117743|Flavobacteriia,2PA5P@246874|Cryomorphaceae	976|Bacteroidetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	-	-	-	-	-	-	-	-	-	TamB
TLS3_k127_3275943_0	755732.Fluta_0507	1.71e-149	480.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,1HWSG@117743|Flavobacteriia,2PACB@246874|Cryomorphaceae	976|Bacteroidetes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
TLS3_k127_3275943_4	755732.Fluta_0406	3.105e-28	117.0	2ENZ2@1|root,33GJY@2|Bacteria,4NZ6P@976|Bacteroidetes,1IIF3@117743|Flavobacteriia,2PC5A@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3275943_1	755732.Fluta_0405	5.082e-41	155.0	COG4232@1|root,COG4232@2|Bacteria,4NQID@976|Bacteroidetes,1I338@117743|Flavobacteriia	976|Bacteroidetes	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
TLS3_k127_3275943_3	755732.Fluta_0404	2.297e-39	154.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1HX34@117743|Flavobacteriia,2PAKN@246874|Cryomorphaceae	976|Bacteroidetes	CO	Cytochrome c biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
TLS3_k127_3283399_3	333138.LQ50_05655	1.909e-21	102.0	COG2936@1|root,COG2936@2|Bacteria,1TT0H@1239|Firmicutes,4HC37@91061|Bacilli,1ZE6G@1386|Bacillus	91061|Bacilli	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
TLS3_k127_3283399_5	746697.Aeqsu_2042	0.0007093	49.0	COG2706@1|root,COG3227@1|root,COG2706@2|Bacteria,COG3227@2|Bacteria,4PP03@976|Bacteroidetes,1I8YI@117743|Flavobacteriia	976|Bacteroidetes	EG	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS3_k127_3283399_2	755732.Fluta_1261	2.838e-25	117.0	2DK3Y@1|root,308D7@2|Bacteria,4PIF2@976|Bacteroidetes,1ICSY@117743|Flavobacteriia,2PC1P@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3283399_1	755732.Fluta_1260	9.625e-56	198.0	COG1595@1|root,COG1595@2|Bacteria,4NQ7S@976|Bacteroidetes,1ICQB@117743|Flavobacteriia,2PBQ6@246874|Cryomorphaceae	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_3283399_4	1279009.ADICEAN_01177	7.423e-13	81.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,4PKBQ@976|Bacteroidetes,47XXU@768503|Cytophagia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
TLS3_k127_3283399_0	1279009.ADICEAN_00688	7.638e-58	220.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
TLS3_k127_3288137_0	755732.Fluta_2369	3.568e-224	725.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,1HXIH@117743|Flavobacteriia,2PBJP@246874|Cryomorphaceae	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
TLS3_k127_3288137_1	755732.Fluta_2368	9.878e-12	69.0	COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,1HY9B@117743|Flavobacteriia,2PAZ0@246874|Cryomorphaceae	976|Bacteroidetes	J	SpoU rRNA Methylase family	aviRb	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
TLS3_k127_3300907_3	926562.Oweho_0225	8.295e-98	332.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,1ICDM@117743|Flavobacteriia,2PBYH@246874|Cryomorphaceae	976|Bacteroidetes	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897,ko:K18660	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,PP-binding
TLS3_k127_3300907_5	926562.Oweho_0226	2.025e-67	245.0	COG0644@1|root,COG0644@2|Bacteria,4PKHH@976|Bacteroidetes,1IJ96@117743|Flavobacteriia	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
TLS3_k127_3300907_2	926562.Oweho_0229	4.326e-112	376.0	COG0842@1|root,COG0842@2|Bacteria,4NGFA@976|Bacteroidetes,1HYPT@117743|Flavobacteriia,2PAFC@246874|Cryomorphaceae	976|Bacteroidetes	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
TLS3_k127_3300907_4	1341155.FSS13T_06180	2.09e-80	275.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HZ6V@117743|Flavobacteriia,2NU6F@237|Flavobacterium	976|Bacteroidetes	V	Multidrug ABC transporter ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_3300907_1	1408433.JHXV01000002_gene371	6.755e-142	463.0	COG4409@1|root,COG4409@2|Bacteria,4NJCZ@976|Bacteroidetes,1I0GI@117743|Flavobacteriia,2PBJF@246874|Cryomorphaceae	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TLS3_k127_3300907_0	755732.Fluta_3142	1.413e-231	733.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1HYRP@117743|Flavobacteriia,2PBEM@246874|Cryomorphaceae	976|Bacteroidetes	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
TLS3_k127_3300907_6	1408433.JHXV01000017_gene1569	1.124e-64	232.0	COG4372@1|root,COG4372@2|Bacteria	2|Bacteria	Q	Transposase	CP_1117	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	Methyltransf_11,UPF0242
TLS3_k127_3300907_8	929556.Solca_4416	5.569e-12	68.0	COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,1ITC4@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
TLS3_k127_3301072_2	143224.JQMD01000002_gene2953	3.9e-43	160.0	COG0702@1|root,COG0702@2|Bacteria,4NG89@976|Bacteroidetes,1I18P@117743|Flavobacteriia	976|Bacteroidetes	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
TLS3_k127_3301072_0	755732.Fluta_0686	5.938e-295	915.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1HYA0@117743|Flavobacteriia,2PACP@246874|Cryomorphaceae	976|Bacteroidetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
TLS3_k127_3301072_1	1121904.ARBP01000011_gene1528	1.783e-51	186.0	COG3427@1|root,COG3427@2|Bacteria,4NQ8R@976|Bacteroidetes,47W10@768503|Cytophagia	976|Bacteroidetes	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_3301072_3	755732.Fluta_2083	4.499e-13	83.0	COG3291@1|root,COG3291@2|Bacteria,4P4C7@976|Bacteroidetes	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_3303912_4	755732.Fluta_0665	2.072e-200	638.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1HYK7@117743|Flavobacteriia,2PAB8@246874|Cryomorphaceae	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
TLS3_k127_3303912_0	755732.Fluta_2357	0.0	1452.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1HYA4@117743|Flavobacteriia,2PAKU@246874|Cryomorphaceae	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
TLS3_k127_3303912_7	688270.Celal_2898	1.209e-67	236.0	COG4894@1|root,COG4894@2|Bacteria,4NKQU@976|Bacteroidetes,1I0KG@117743|Flavobacteriia,1F8D1@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3303912_2	755732.Fluta_2384	5.855e-230	728.0	COG0308@1|root,COG0308@2|Bacteria,4NFT0@976|Bacteroidetes,1I0K4@117743|Flavobacteriia,2PA80@246874|Cryomorphaceae	976|Bacteroidetes	E	Leukotriene A4 hydrolase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
TLS3_k127_3303912_3	1349785.BAUG01000023_gene1483	1.527e-211	670.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1HWTF@117743|Flavobacteriia	976|Bacteroidetes	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
TLS3_k127_3303912_1	1122176.KB903565_gene3410	2.213e-281	878.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1IQFI@117747|Sphingobacteriia	976|Bacteroidetes	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
TLS3_k127_3303912_5	1347342.BN863_7900	1.213e-156	511.0	COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes,1HX29@117743|Flavobacteriia	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
TLS3_k127_3303912_8	376686.Fjoh_3485	4.958e-49	184.0	COG0491@1|root,COG0491@2|Bacteria,4NPPW@976|Bacteroidetes,1I25P@117743|Flavobacteriia,2NTZ3@237|Flavobacterium	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	blaB	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
TLS3_k127_3303912_6	755732.Fluta_2823	8.932e-121	394.0	COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,1HYJM@117743|Flavobacteriia,2PAJ2@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
TLS3_k127_3318544_0	1185876.BN8_02865	2.325e-72	270.0	COG0745@1|root,COG1956@1|root,COG5002@1|root,COG0745@2|Bacteria,COG1956@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,47YRP@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HTH_18,HisKA,Response_reg,TPR_10,TPR_12,TPR_7,TPR_8
TLS3_k127_3318544_1	1142394.PSMK_05160	2.642e-07	58.0	COG3209@1|root,COG4386@1|root,COG3209@2|Bacteria,COG4386@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,Laminin_G_3
TLS3_k127_3325165_1	760192.Halhy_0214	3.978e-88	315.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,4PN79@976|Bacteroidetes	976|Bacteroidetes	G	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_3325165_0	1408433.JHXV01000021_gene1675	2.423e-152	488.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1HXAN@117743|Flavobacteriia,2PBH1@246874|Cryomorphaceae	976|Bacteroidetes	L	DNA polymerase III subunits gamma and tau domain III	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
TLS3_k127_3339959_0	755732.Fluta_0606	8.31e-207	668.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,1I54C@117743|Flavobacteriia,2PAIC@246874|Cryomorphaceae	976|Bacteroidetes	Q	PFAM FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS3_k127_3339959_2	744872.Spica_0058	1.275e-26	113.0	COG1051@1|root,COG1051@2|Bacteria,2J926@203691|Spirochaetes	203691|Spirochaetes	F	TIGRFAM mutator mutT protein	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
TLS3_k127_3339959_3	1121288.AULL01000013_gene1848	1.436e-13	76.0	2BFVS@1|root,329R5@2|Bacteria,4PGMB@976|Bacteroidetes,1IFB4@117743|Flavobacteriia,3ZTQJ@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3339959_1	102125.Xen7305DRAFT_00006940	2.595e-69	248.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TLS3_k127_3341724_0	755732.Fluta_3905	9.751e-285	897.0	COG0265@1|root,COG3673@1|root,COG0265@2|Bacteria,COG3673@2|Bacteria,4PNUK@976|Bacteroidetes,1IKEA@117743|Flavobacteriia,2PA7S@246874|Cryomorphaceae	976|Bacteroidetes	O	Peptide-N-glycosidase F, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,N-glycanase_C
TLS3_k127_3341724_1	929556.Solca_3651	1.634e-08	57.0	COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes,1IQ41@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
TLS3_k127_3371957_3	760192.Halhy_3729	6.693e-18	93.0	2AGP0@1|root,316WI@2|Bacteria,4P75W@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3371957_0	1408813.AYMG01000010_gene308	1.814e-79	273.0	COG1633@1|root,COG1633@2|Bacteria,4NKSU@976|Bacteroidetes,1IS2F@117747|Sphingobacteriia	976|Bacteroidetes	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3371957_1	1408433.JHXV01000028_gene2115	6.138e-60	214.0	2BXI0@1|root,2Z9A2@2|Bacteria,4NFDQ@976|Bacteroidetes,1IGDK@117743|Flavobacteriia,2PBYU@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF2459)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2459
TLS3_k127_3371957_2	694427.Palpr_1598	9.813e-51	183.0	COG0454@1|root,COG0456@2|Bacteria,4NNG9@976|Bacteroidetes,2FTBE@200643|Bacteroidia,230CS@171551|Porphyromonadaceae	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
TLS3_k127_3387682_5	1280952.HJA_13655	1.872e-44	171.0	COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,2TTWH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	MA20_24385	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_3387682_2	562970.Btus_3156	1.655e-71	259.0	COG0277@1|root,COG0277@2|Bacteria,1UIU4@1239|Firmicutes,4HBGZ@91061|Bacilli	91061|Bacilli	C	PFAM FAD linked oxidase domain protein	yitY	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
TLS3_k127_3387682_7	1325130.HFN_1661	1.748e-27	123.0	COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,42PEU@68525|delta/epsilon subdivisions,2YP21@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
TLS3_k127_3387682_3	755732.Fluta_1827	1.096e-67	241.0	29Y6P@1|root,30K06@2|Bacteria,4PI0C@976|Bacteroidetes,1ICR1@117743|Flavobacteriia,2PBTZ@246874|Cryomorphaceae	976|Bacteroidetes	S	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Omp28
TLS3_k127_3387682_4	755732.Fluta_1827	1.238e-67	243.0	29Y6P@1|root,30K06@2|Bacteria,4PI0C@976|Bacteroidetes,1ICR1@117743|Flavobacteriia,2PBTZ@246874|Cryomorphaceae	976|Bacteroidetes	S	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Omp28
TLS3_k127_3387682_0	755732.Fluta_1828	1.488e-209	666.0	2CIBF@1|root,2Z85N@2|Bacteria,4NF0J@976|Bacteroidetes,1HYX2@117743|Flavobacteriia,2PA9Q@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3387682_1	755732.Fluta_1829	5.581e-86	286.0	COG0526@1|root,COG0526@2|Bacteria,4NNHX@976|Bacteroidetes,1I33N@117743|Flavobacteriia,2PAUY@246874|Cryomorphaceae	976|Bacteroidetes	CO	AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
TLS3_k127_3387682_10	1408433.JHXV01000001_gene656	2.49e-07	61.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
TLS3_k127_3387682_8	755732.Fluta_1831	1.453e-17	92.0	COG3291@1|root,COG3291@2|Bacteria,4P5U5@976|Bacteroidetes,1IAAB@117743|Flavobacteriia,2PB83@246874|Cryomorphaceae	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3387682_6	755732.Fluta_1923	5.941e-40	158.0	COG0810@1|root,COG0810@2|Bacteria,4PKAV@976|Bacteroidetes,1HWXW@117743|Flavobacteriia	976|Bacteroidetes	M	Gliding motility protein RemB	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
TLS3_k127_3389319_3	551789.ATVJ01000001_gene550	7.945e-32	139.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria,43ZTI@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
TLS3_k127_3389319_0	755732.Fluta_1262	2.337e-198	638.0	COG1300@1|root,COG1300@2|Bacteria,4NG8D@976|Bacteroidetes,1HWW9@117743|Flavobacteriia,2PANT@246874|Cryomorphaceae	976|Bacteroidetes	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
TLS3_k127_3389319_2	755732.Fluta_1263	1.534e-52	196.0	29GF6@1|root,303CZ@2|Bacteria,4NVCX@976|Bacteroidetes,1IG3S@117743|Flavobacteriia,2PBA7@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
TLS3_k127_3389319_1	755732.Fluta_1264	3.276e-66	246.0	28IVH@1|root,2Z8TX@2|Bacteria,4NEEW@976|Bacteroidetes,1HXTG@117743|Flavobacteriia,2PB85@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
TLS3_k127_3394241_0	489825.LYNGBM3L_48850	1.082e-20	108.0	COG1239@1|root,COG1239@2|Bacteria,1GQHW@1117|Cyanobacteria,1HE6P@1150|Oscillatoriales	1117|Cyanobacteria	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3401514_7	1341181.FLJC2902T_13950	4.946e-105	372.0	COG1572@1|root,COG3210@1|root,COG3291@1|root,COG5492@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NURE@237|Flavobacterium	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHU_C,HYR,SprB
TLS3_k127_3401514_27	755732.Fluta_3353	1.546e-12	81.0	COG5184@1|root,COG5184@2|Bacteria,4PKDT@976|Bacteroidetes	976|Bacteroidetes	DZ	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_3401514_15	1408433.JHXV01000010_gene535	2.053e-44	168.0	2AAU0@1|root,30Y70@2|Bacteria,4PBYC@976|Bacteroidetes,1ICQX@117743|Flavobacteriia,2PBTU@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3401514_32	1338011.BD94_2645	0.000539	43.0	2DGCB@1|root,2ZVDX@2|Bacteria,4P8DI@976|Bacteroidetes,1IBH1@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3401514_16	755732.Fluta_3286	9.05e-44	161.0	COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,1I2UU@117743|Flavobacteriia,2PB6Z@246874|Cryomorphaceae	976|Bacteroidetes	J	Translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
TLS3_k127_3401514_10	755732.Fluta_3287	1.985e-82	278.0	COG2065@1|root,COG2065@2|Bacteria,4NFI1@976|Bacteroidetes,1HXQM@117743|Flavobacteriia,2PAT6@246874|Cryomorphaceae	976|Bacteroidetes	F	Phosphoribosyl transferase domain	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
TLS3_k127_3401514_5	755732.Fluta_3288	4.192e-174	550.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,1HXQ7@117743|Flavobacteriia,2PAID@246874|Cryomorphaceae	976|Bacteroidetes	F	PFAM Aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
TLS3_k127_3401514_19	755732.Fluta_3289	1.642e-37	143.0	COG1366@1|root,COG1366@2|Bacteria,4NTPB@976|Bacteroidetes,1ICRT@117743|Flavobacteriia,2PBXB@246874|Cryomorphaceae	976|Bacteroidetes	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
TLS3_k127_3401514_8	755732.Fluta_3290	1.989e-92	312.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,1HXBQ@117743|Flavobacteriia,2PARS@246874|Cryomorphaceae	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
TLS3_k127_3401514_1	755732.Fluta_4076	0.0	1094.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,1HWNY@117743|Flavobacteriia,2PAF4@246874|Cryomorphaceae	976|Bacteroidetes	L	Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
TLS3_k127_3401514_0	755732.Fluta_4075	0.0	1421.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia,2PAGK@246874|Cryomorphaceae	976|Bacteroidetes	L	PFAM DNA gyrase topoisomerase IV, subunit A	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
TLS3_k127_3401514_12	880070.Cycma_0863	3.573e-70	245.0	COG3040@1|root,COG3040@2|Bacteria,4NNFA@976|Bacteroidetes,47QWX@768503|Cytophagia	976|Bacteroidetes	M	Lipocalin / cytosolic fatty-acid binding protein family	blc	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
TLS3_k127_3401514_28	561177.ANHYDRO_00577	1.572e-10	73.0	COG2312@1|root,COG2312@2|Bacteria,1V2ED@1239|Firmicutes,24BHP@186801|Clostridia,22GJK@1570339|Peptoniphilaceae	186801|Clostridia	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
TLS3_k127_3401514_24	1408433.JHXV01000014_gene3638	5.448e-23	115.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,4NHY5@976|Bacteroidetes,1HZI3@117743|Flavobacteriia	976|Bacteroidetes	JM	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N,fn3
TLS3_k127_3401514_20	1484460.JSWG01000006_gene2731	3.009e-35	154.0	COG1470@1|root,COG2931@1|root,COG3266@1|root,COG3420@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria,COG3266@2|Bacteria,COG3420@2|Bacteria,4NQBS@976|Bacteroidetes	976|Bacteroidetes	Q	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
TLS3_k127_3401514_4	755732.Fluta_4071	8.357e-215	674.0	COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,1HZCP@117743|Flavobacteriia,2PA5I@246874|Cryomorphaceae	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
TLS3_k127_3401514_17	391625.PPSIR1_30631	8.765e-40	165.0	COG1719@1|root,COG1719@2|Bacteria	2|Bacteria	KT	4-vinyl reductase, 4VR	-	-	3.1.3.16	ko:K06382,ko:K07013	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c,SpoIIE,V4R
TLS3_k127_3401514_21	868131.MSWAN_1308	7.69e-35	150.0	COG0642@1|root,COG3920@1|root,arCOG02327@2157|Archaea,arCOG02335@2157|Archaea	2157|Archaea	T	PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	BAT,GAF,GAF_2,HATPase_c,HTH_10,HisKA,HisKA_2,HisKA_7TM,PAS,PAS_4,PAS_8,PAS_9,Response_reg
TLS3_k127_3401514_3	755732.Fluta_4067	9.081e-224	700.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1HWVH@117743|Flavobacteriia,2PBCM@246874|Cryomorphaceae	976|Bacteroidetes	G	PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TLS3_k127_3401514_6	1122226.AUHX01000001_gene854	1.979e-155	497.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,1HYC0@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
TLS3_k127_3401514_25	1121007.AUML01000001_gene1321	6.024e-21	96.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1HXU8@117743|Flavobacteriia,2YKGH@290174|Aquimarina	976|Bacteroidetes	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
TLS3_k127_3401514_11	1121007.AUML01000001_gene1321	1.85e-80	273.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1HXU8@117743|Flavobacteriia,2YKGH@290174|Aquimarina	976|Bacteroidetes	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
TLS3_k127_3401514_18	755732.Fluta_0574	1.54e-39	155.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,1I0S7@117743|Flavobacteriia	976|Bacteroidetes	KT	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_3401514_31	886379.AEWI01000127_gene1894	4.733e-05	48.0	COG3093@1|root,COG3093@2|Bacteria,4NVPC@976|Bacteroidetes	976|Bacteroidetes	K	addiction module antidote protein HigA	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
TLS3_k127_3401514_9	313603.FB2170_07604	3.218e-89	301.0	298PG@1|root,2ZVTY@2|Bacteria,4NKI7@976|Bacteroidetes,1I26G@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3401514_22	525257.HMPREF0204_13257	2.091e-32	141.0	COG3292@1|root,COG5184@1|root,COG3292@2|Bacteria,COG5184@2|Bacteria,4PHXH@976|Bacteroidetes,1I73G@117743|Flavobacteriia,3ZUBQ@59732|Chryseobacterium	976|Bacteroidetes	DTZ	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,Reg_prop
TLS3_k127_3401514_23	1313421.JHBV01000039_gene2758	4.204e-24	119.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
TLS3_k127_3401514_30	391625.PPSIR1_19814	1.991e-05	58.0	COG3591@1|root,COG3591@2|Bacteria,1QX7V@1224|Proteobacteria,43C0V@68525|delta/epsilon subdivisions,2X7BH@28221|Deltaproteobacteria,2YV6V@29|Myxococcales	28221|Deltaproteobacteria	E	Lysyl oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Lysyl_oxidase
TLS3_k127_3401514_29	867902.Ornrh_2367	2.971e-06	55.0	2AVDM@1|root,31M58@2|Bacteria,4NUN6@976|Bacteroidetes,1I278@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4293
TLS3_k127_3401514_2	755732.Fluta_4057	1.6e-290	902.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1HY5T@117743|Flavobacteriia,2PAEQ@246874|Cryomorphaceae	976|Bacteroidetes	S	ABC transporter C-terminal domain	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
TLS3_k127_3401514_14	1286632.P278_30870	1.655e-44	169.0	COG0500@1|root,COG2226@2|Bacteria,4PM4H@976|Bacteroidetes,1IJJ7@117743|Flavobacteriia	976|Bacteroidetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_3401514_13	1121904.ARBP01000004_gene984	1.534e-46	174.0	COG2143@1|root,COG2143@2|Bacteria,4NM6B@976|Bacteroidetes,47Q2D@768503|Cytophagia	976|Bacteroidetes	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7
TLS3_k127_3439106_0	1408433.JHXV01000001_gene1052	3.714e-77	278.0	COG3291@1|root,COG3291@2|Bacteria,4NG09@976|Bacteroidetes,1IKC9@117743|Flavobacteriia	976|Bacteroidetes	N	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3439106_1	1121012.AUKX01000039_gene3179	3.35e-25	115.0	COG0589@1|root,COG0589@2|Bacteria,4NF5D@976|Bacteroidetes,1HZH6@117743|Flavobacteriia,23FUJ@178469|Arenibacter	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_344863_1	1408433.JHXV01000039_gene2184	0.0	1266.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,1HYTK@117743|Flavobacteriia,2PB8R@246874|Cryomorphaceae	976|Bacteroidetes	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
TLS3_k127_344863_5	1408433.JHXV01000039_gene2186	6.378e-56	211.0	COG2304@1|root,COG2304@2|Bacteria,4NST4@976|Bacteroidetes,1I9XN@117743|Flavobacteriia,2PC0P@246874|Cryomorphaceae	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_344863_0	1408433.JHXV01000039_gene2187	0.0	1607.0	COG3188@1|root,COG3188@2|Bacteria,4NHVA@976|Bacteroidetes,1I023@117743|Flavobacteriia,2PBJH@246874|Cryomorphaceae	976|Bacteroidetes	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	PA14
TLS3_k127_344863_12	153721.MYP_2986	4.225e-12	72.0	COG2825@1|root,COG2825@2|Bacteria,4P9UH@976|Bacteroidetes,47WKD@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TLS3_k127_344863_15	1408433.JHXV01000039_gene2189	3.129e-08	66.0	28ZIA@1|root,2ZM9Q@2|Bacteria,4P3YS@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_344863_6	1408433.JHXV01000034_gene5	2.27e-39	154.0	COG2197@1|root,COG2197@2|Bacteria,4NMTW@976|Bacteroidetes,1I1JF@117743|Flavobacteriia,2PBU0@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_344863_14	153721.MYP_2884	1.683e-09	65.0	2DR3V@1|root,33A26@2|Bacteria,4NZ0R@976|Bacteroidetes,47WD9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_344863_8	1270193.JARP01000007_gene207	1.038e-32	139.0	COG4733@1|root,COG4733@2|Bacteria,4NT4E@976|Bacteroidetes,1I3YW@117743|Flavobacteriia,2NUAW@237|Flavobacterium	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_344863_11	1443665.JACA01000026_gene3536	1.702e-15	84.0	2E4UH@1|root,32ZNV@2|Bacteria,4NWQC@976|Bacteroidetes,1I5CJ@117743|Flavobacteriia,2YGJD@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_344863_10	1270193.JARP01000007_gene209	1.009e-23	114.0	2CE49@1|root,3333T@2|Bacteria,4NW49@976|Bacteroidetes,1I689@117743|Flavobacteriia,2NZWV@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilN
TLS3_k127_344863_3	1317122.ATO12_13730	9.962e-150	498.0	COG4796@1|root,COG4796@2|Bacteria,4NGRG@976|Bacteroidetes,1I06V@117743|Flavobacteriia,2YHE7@290174|Aquimarina	976|Bacteroidetes	U	Bacterial type II and III secretion system protein	gspD	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	STN,Secretin,Secretin_N
TLS3_k127_344863_2	1408433.JHXV01000054_gene1546	2.979e-180	576.0	COG2804@1|root,COG2804@2|Bacteria,4NHT2@976|Bacteroidetes,1HZ5C@117743|Flavobacteriia	976|Bacteroidetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	gspE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
TLS3_k127_344863_13	525373.HMPREF0766_12193	9.761e-11	68.0	2ECR5@1|root,336NV@2|Bacteria,4NWGD@976|Bacteroidetes,1IUJC@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_A24
TLS3_k127_344863_9	1408473.JHXO01000008_gene2944	3.932e-31	126.0	COG4968@1|root,COG4968@2|Bacteria,4NNW6@976|Bacteroidetes,2FTFZ@200643|Bacteroidia	976|Bacteroidetes	NU	Prokaryotic N-terminal methylation motif	gspG	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
TLS3_k127_344863_4	1121007.AUML01000024_gene364	2.222e-106	355.0	COG1459@1|root,COG1459@2|Bacteria,4NHKM@976|Bacteroidetes,1I02V@117743|Flavobacteriia,2YH39@290174|Aquimarina	976|Bacteroidetes	NU	Type II secretion system (T2SS), protein F	gspF	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
TLS3_k127_344863_7	1443665.JACA01000026_gene3545	3.994e-37	152.0	2DM2H@1|root,31FIM@2|Bacteria,4NQH1@976|Bacteroidetes,1I3RC@117743|Flavobacteriia,2YHYY@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3461755_4	394.NGR_c01250	0.0003157	46.0	COG2856@1|root,COG2856@2|Bacteria,1PFUN@1224|Proteobacteria,2UDZS@28211|Alphaproteobacteria,4B81R@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31,Peptidase_M78
TLS3_k127_3461755_1	394.NGR_c01240	7.733e-38	147.0	COG5166@1|root,COG5166@2|Bacteria,1QU5F@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4411)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4411
TLS3_k127_3461755_2	1121897.AUGO01000016_gene1075	5.507e-29	125.0	COG0596@1|root,COG0596@2|Bacteria,4PKKR@976|Bacteroidetes,1IJBZ@117743|Flavobacteriia,2NYSA@237|Flavobacterium	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,UPF0227
TLS3_k127_3461755_0	365044.Pnap_0378	2.383e-65	233.0	2CDN0@1|root,2ZFU0@2|Bacteria,1RC0D@1224|Proteobacteria,2VQVK@28216|Betaproteobacteria,4AH1F@80864|Comamonadaceae	28216|Betaproteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
TLS3_k127_3461755_3	365044.Pnap_0377	1.591e-22	102.0	2DTWF@1|root,32UW3@2|Bacteria,1ND7X@1224|Proteobacteria,2VW14@28216|Betaproteobacteria,4AI13@80864|Comamonadaceae	28216|Betaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
TLS3_k127_3472544_1	755732.Fluta_1309	3.652e-127	419.0	COG2272@1|root,COG2272@2|Bacteria,4PI06@976|Bacteroidetes,1IG13@117743|Flavobacteriia,2PB7F@246874|Cryomorphaceae	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	COesterase
TLS3_k127_3472544_2	1121373.KB903621_gene1879	4.011e-117	391.0	COG2755@1|root,COG2755@2|Bacteria,4NGTK@976|Bacteroidetes,47NWX@768503|Cytophagia	976|Bacteroidetes	E	GDSL family lipolytic protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
TLS3_k127_3472544_0	269798.CHU_3521	1.954e-139	454.0	COG2067@1|root,COG2067@2|Bacteria,4NFFF@976|Bacteroidetes,47NDV@768503|Cytophagia	976|Bacteroidetes	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
TLS3_k127_3472544_4	755732.Fluta_3982	1.34e-63	223.0	COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,1I17W@117743|Flavobacteriia,2PAQI@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
TLS3_k127_3472544_3	755732.Fluta_3983	1.072e-69	239.0	COG0806@1|root,COG0806@2|Bacteria,4NQF0@976|Bacteroidetes,1I17F@117743|Flavobacteriia,2PAUS@246874|Cryomorphaceae	976|Bacteroidetes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
TLS3_k127_3472544_5	742727.HMPREF9447_00252	2.374e-46	175.0	COG4123@1|root,COG4123@2|Bacteria,4NG1X@976|Bacteroidetes,2FMHH@200643|Bacteroidia,4AN81@815|Bacteroidaceae	976|Bacteroidetes	J	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	smtA	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
TLS3_k127_3529685_2	1121912.AUHD01000001_gene2360	1.103e-26	112.0	2E77I@1|root,331RA@2|Bacteria,4NUW5@976|Bacteroidetes,1I5T1@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3529685_3	1121889.AUDM01000002_gene423	6.902e-07	57.0	COG2913@1|root,COG2913@2|Bacteria,4NP4N@976|Bacteroidetes,1I2RK@117743|Flavobacteriia	976|Bacteroidetes	J	Domain of unknown function (DUF4476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4476,SmpA_OmlA
TLS3_k127_3529685_4	1123058.KB894220_gene2159	2.694e-05	57.0	COG5164@1|root,COG5295@1|root,COG5164@2|Bacteria,COG5295@2|Bacteria,4NX8D@976|Bacteroidetes	976|Bacteroidetes	K	Collagen triple helix repeat	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,DUF4988,LRR_5
TLS3_k127_3529685_0	984262.SGRA_2738	1.132e-161	526.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4842,PEGA
TLS3_k127_3624809_0	385682.AFSL01000002_gene1845	9.474e-44	164.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,2FKZQ@200643|Bacteroidia,3XIVW@558415|Marinilabiliaceae	976|Bacteroidetes	H	ApbE family	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
TLS3_k127_3624809_1	1453498.LG45_07930	1.172e-35	146.0	COG3656@1|root,COG3656@2|Bacteria	2|Bacteria	N	Periplasmic Protein	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Fib_succ_major,TIG
TLS3_k127_3624809_2	1128427.KB904821_gene3148	5.524e-15	83.0	COG0457@1|root,COG0457@2|Bacteria,1G8MC@1117|Cyanobacteria,1HG14@1150|Oscillatoriales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M10,TPR_1,TPR_11,TPR_16,TPR_8
TLS3_k127_3624809_3	1122176.KB903537_gene1600	1.356e-06	51.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
TLS3_k127_3624895_0	755732.Fluta_2423	2.99e-254	801.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1I7ZV@117743|Flavobacteriia,2PAMN@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
TLS3_k127_3630739_0	755732.Fluta_2739	1.482e-271	852.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,1HY3A@117743|Flavobacteriia,2PACE@246874|Cryomorphaceae	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	dpp	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
TLS3_k127_3630739_1	1406840.Q763_00530	3.227e-214	670.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1HWVX@117743|Flavobacteriia,2NS60@237|Flavobacterium	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
TLS3_k127_3666176_2	1121896.JMLU01000007_gene205	1.481e-150	493.0	COG0507@1|root,COG4955@1|root,COG0507@2|Bacteria,COG4955@2|Bacteria,4NF6J@976|Bacteroidetes,1HZ14@117743|Flavobacteriia,2NU7F@237|Flavobacterium	976|Bacteroidetes	L	Helicase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_40,Herpes_Helicase,PIF1,UvrD_C_2
TLS3_k127_3666176_4	1218108.KB908291_gene810	8.02e-39	148.0	COG0346@1|root,COG0346@2|Bacteria,4NQK6@976|Bacteroidetes,1I4MY@117743|Flavobacteriia	976|Bacteroidetes	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_2
TLS3_k127_3666176_0	755732.Fluta_1461	1.508e-198	634.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1HXAP@117743|Flavobacteriia,2PADQ@246874|Cryomorphaceae	976|Bacteroidetes	L	DHH family	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
TLS3_k127_3666176_3	755732.Fluta_2398	8.012e-87	299.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IFTS@117743|Flavobacteriia,2PBTH@246874|Cryomorphaceae	976|Bacteroidetes	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_3666176_5	485918.Cpin_1738	2.273e-15	92.0	COG3291@1|root,COG3291@2|Bacteria,4NJQN@976|Bacteroidetes,1IXWG@117747|Sphingobacteriia	976|Bacteroidetes	M	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,IgGFc_binding,PKD,SprB,fn3
TLS3_k127_3666176_1	929556.Solca_2664	6.952e-198	666.0	COG2374@1|root,COG3209@1|root,COG3210@1|root,COG3391@1|root,COG4886@1|root,COG4932@1|root,COG5492@1|root,COG2374@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
TLS3_k127_3667001_0	1461577.CCMH01000037_gene4	4.407e-50	193.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1I0IG@117743|Flavobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_3667001_2	1313421.JHBV01000042_gene3261	1.146e-19	98.0	COG2353@1|root,COG3210@1|root,COG2353@2|Bacteria,COG3210@2|Bacteria,4NIDX@976|Bacteroidetes	976|Bacteroidetes	U	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_3667001_1	497965.Cyan7822_3350	1.527e-29	128.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG3437@1|root,COG3829@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1G09B@1117|Cyanobacteria,3KJDH@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_3674958_0	755732.Fluta_1986	3.187e-188	612.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,1HXT3@117743|Flavobacteriia,2PATZ@246874|Cryomorphaceae	976|Bacteroidetes	O	SurA N-terminal domain	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
TLS3_k127_3674958_1	1408433.JHXV01000040_gene1533	1.141e-96	328.0	COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,1HXG0@117743|Flavobacteriia,2PAKJ@246874|Cryomorphaceae	976|Bacteroidetes	L	DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
TLS3_k127_3674958_2	1313421.JHBV01000041_gene3398	2.031e-60	224.0	COG4206@1|root,COG4206@2|Bacteria,4NIJS@976|Bacteroidetes	976|Bacteroidetes	H	COG4206 Outer membrane cobalamin receptor protein	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_3680650_0	984262.SGRA_3562	6.98e-174	570.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1IYS6@117747|Sphingobacteriia	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
TLS3_k127_3680650_1	1313421.JHBV01000030_gene2252	6.185e-68	234.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
TLS3_k127_3684009_4	1227266.HMPREF1551_00491	4.461e-24	105.0	COG1861@1|root,COG1861@2|Bacteria,4NPWJ@976|Bacteroidetes,1I2HR@117743|Flavobacteriia	976|Bacteroidetes	M	Cytidylyltransferase	-	-	2.7.7.92	ko:K07257,ko:K21750	-	-	-	-	ko00000,ko01000	-	-	-	CTP_transf_3
TLS3_k127_3684009_1	755732.Fluta_0225	3.673e-304	961.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,1HX3C@117743|Flavobacteriia,2PA54@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
TLS3_k127_3684009_0	755732.Fluta_3835	0.0	1733.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,1HWPA@117743|Flavobacteriia,2PAI4@246874|Cryomorphaceae	976|Bacteroidetes	EF	PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
TLS3_k127_3684009_3	755732.Fluta_3270	1.167e-41	158.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,1I2CB@117743|Flavobacteriia,2PB5R@246874|Cryomorphaceae	976|Bacteroidetes	F	Pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
TLS3_k127_3684009_2	755732.Fluta_3269	1.169e-68	237.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1HXU4@117743|Flavobacteriia,2PA99@246874|Cryomorphaceae	976|Bacteroidetes	H	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
TLS3_k127_3749536_3	755732.Fluta_2913	1.886e-87	300.0	2BJHF@1|root,32DUB@2|Bacteria,4P9RZ@976|Bacteroidetes,1ICNC@117743|Flavobacteriia,2PB7V@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3749536_0	755732.Fluta_2912	2.444e-187	594.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HWZU@117743|Flavobacteriia,2PA9T@246874|Cryomorphaceae	976|Bacteroidetes	I	Thiolase, C-terminal domain	pcaF	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
TLS3_k127_3749536_1	755732.Fluta_2911	3.16e-149	480.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,1I5TM@117743|Flavobacteriia,2PBI1@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
TLS3_k127_3749536_2	755732.Fluta_2910	1.789e-93	319.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1HYK6@117743|Flavobacteriia,2PBIS@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
TLS3_k127_3761958_6	755732.Fluta_2335	3.459e-14	74.0	COG2981@1|root,COG2981@2|Bacteria,4NHXY@976|Bacteroidetes,1HXWD@117743|Flavobacteriia,2PBQT@246874|Cryomorphaceae	976|Bacteroidetes	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
TLS3_k127_3761958_1	755732.Fluta_2336	7.391e-213	669.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,1HXVA@117743|Flavobacteriia,2PAGN@246874|Cryomorphaceae	976|Bacteroidetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
TLS3_k127_3761958_5	1121373.KB903621_gene1779	5.559e-27	127.0	2DBNY@1|root,2ZA6F@2|Bacteria,4NTM4@976|Bacteroidetes,47RWF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3761958_8	1165096.ARWF01000001_gene2085	9.953e-05	48.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2W81G@28216|Betaproteobacteria,2KNB0@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
TLS3_k127_3761958_4	1408433.JHXV01000009_gene1326	2.217e-46	173.0	COG1595@1|root,COG1595@2|Bacteria,4NHNI@976|Bacteroidetes,1HY4K@117743|Flavobacteriia,2PBYA@246874|Cryomorphaceae	976|Bacteroidetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_3761958_2	755732.Fluta_2338	2.42e-152	497.0	COG0815@1|root,COG0815@2|Bacteria,4NG4X@976|Bacteroidetes,1HY5K@117743|Flavobacteriia,2PA50@246874|Cryomorphaceae	976|Bacteroidetes	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
TLS3_k127_3761958_3	1121931.AUHG01000010_gene506	7.96e-50	184.0	COG1670@1|root,COG1670@2|Bacteria,4NNBE@976|Bacteroidetes,1I22F@117743|Flavobacteriia	976|Bacteroidetes	J	Polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_3761958_0	755732.Fluta_2344	1.202e-291	919.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY0A@117743|Flavobacteriia,2PBF0@246874|Cryomorphaceae	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
TLS3_k127_377071_0	1121373.KB903628_gene1416	4.921e-106	346.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,47MBG@768503|Cytophagia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	yadF	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
TLS3_k127_377071_1	795797.C497_10128	9.022e-50	183.0	COG1247@1|root,arCOG00830@2157|Archaea,2XXA1@28890|Euryarchaeota,23VUW@183963|Halobacteria	183963|Halobacteria	K	COG1247 Sortase and related acyltransferases	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
TLS3_k127_377071_3	69042.WH5701_10380	2.412e-27	116.0	COG3837@1|root,COG3837@2|Bacteria,1G5P0@1117|Cyanobacteria,1H16C@1129|Synechococcus	1117|Cyanobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_377071_2	509635.N824_20210	8.336e-43	164.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,1IT3A@117747|Sphingobacteriia	976|Bacteroidetes	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_3814392_7	1216967.L100_02872	4.38e-08	57.0	COG2104@1|root,COG2104@2|Bacteria,4NX2F@976|Bacteroidetes,1I6BK@117743|Flavobacteriia,34RRT@308865|Elizabethkingia	976|Bacteroidetes	H	ThiS family	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
TLS3_k127_3814392_0	1408433.JHXV01000020_gene3528	0.0	1099.0	COG0422@1|root,COG0422@2|Bacteria,4NFTF@976|Bacteroidetes,1HZ6B@117743|Flavobacteriia,2PBAB@246874|Cryomorphaceae	976|Bacteroidetes	H	ThiC-associated domain	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
TLS3_k127_3814392_5	1121904.ARBP01000005_gene4514	1.197e-35	143.0	COG0352@1|root,COG0352@2|Bacteria,4NRDR@976|Bacteroidetes,47RRW@768503|Cytophagia	976|Bacteroidetes	H	Thiamine monophosphate synthase	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
TLS3_k127_3814392_3	153721.MYP_4583	1.546e-69	243.0	COG0351@1|root,COG0351@2|Bacteria,4NE0F@976|Bacteroidetes,47PMU@768503|Cytophagia	976|Bacteroidetes	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
TLS3_k127_3814392_4	926549.KI421517_gene2593	1.585e-58	210.0	COG0352@1|root,COG0352@2|Bacteria,4NNFB@976|Bacteroidetes,47PYU@768503|Cytophagia	976|Bacteroidetes	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin,TMP-TENI
TLS3_k127_3814392_2	1121904.ARBP01000011_gene1510	6.05e-126	406.0	COG2022@1|root,COG2022@2|Bacteria,4NDWY@976|Bacteroidetes,47JAC@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
TLS3_k127_3814392_1	1408433.JHXV01000020_gene3534	2.86e-186	587.0	COG0502@1|root,COG0502@2|Bacteria,4NEI7@976|Bacteroidetes,1HZ5P@117743|Flavobacteriia,2PBCN@246874|Cryomorphaceae	976|Bacteroidetes	H	Biotin and Thiamin Synthesis associated domain	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
TLS3_k127_3814392_6	1042376.AFPK01000071_gene653	3.595e-33	130.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,1HYQ3@117743|Flavobacteriia,406M5@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	H	ThiF family	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
TLS3_k127_383735_0	616991.JPOO01000001_gene3531	1.914e-296	917.0	COG0475@1|root,COG0475@2|Bacteria,4NF11@976|Bacteroidetes,1HWZE@117743|Flavobacteriia,23G2M@178469|Arenibacter	976|Bacteroidetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
TLS3_k127_383735_2	908937.Prede_1226	3.953e-134	432.0	COG0863@1|root,COG0863@2|Bacteria,4NZ6D@976|Bacteroidetes,2G31R@200643|Bacteroidia	976|Bacteroidetes	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
TLS3_k127_383735_1	1454007.JAUG01000146_gene1323	3.201e-138	446.0	COG4977@1|root,COG4977@2|Bacteria,4NGSR@976|Bacteroidetes,1IP0J@117747|Sphingobacteriia	976|Bacteroidetes	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
TLS3_k127_383735_4	1237149.C900_02283	1.108e-50	186.0	COG3832@1|root,COG3832@2|Bacteria,4P4MK@976|Bacteroidetes	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_383735_3	1121007.AUML01000031_gene2711	3.815e-61	214.0	COG3832@1|root,COG3832@2|Bacteria,4NNTR@976|Bacteroidetes,1I2R2@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_3839127_3	504487.JCM19302_1960	2.805e-10	62.0	COG1765@1|root,COG1765@2|Bacteria,4NNZ6@976|Bacteroidetes,1I2C1@117743|Flavobacteriia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
TLS3_k127_3839127_1	1408433.JHXV01000025_gene4034	1.067e-85	289.0	COG0727@1|root,COG0727@2|Bacteria,4NMJ0@976|Bacteroidetes,1I1AF@117743|Flavobacteriia,2PBUS@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
TLS3_k127_3839127_0	755732.Fluta_1878	1.819e-107	358.0	COG2342@1|root,COG2342@2|Bacteria,4P00X@976|Bacteroidetes,1I8EI@117743|Flavobacteriia,2PAQG@246874|Cryomorphaceae	976|Bacteroidetes	G	Glycoside-hydrolase family GH114	-	-	6.1.1.16	ko:K01884	ko00970,map00970	M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Glyco_hydro_114
TLS3_k127_3839127_2	411154.GFO_3261	5.975e-37	141.0	28QUG@1|root,2ZD9S@2|Bacteria,4NMYF@976|Bacteroidetes,1I2AR@117743|Flavobacteriia	976|Bacteroidetes	S	Deoxyuridine 5'-triphosphate nucleotidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3889749_3	1408433.JHXV01000018_gene3841	1.639e-44	164.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1HX06@117743|Flavobacteriia,2PAF0@246874|Cryomorphaceae	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
TLS3_k127_3889749_4	755732.Fluta_3510	2.27e-39	159.0	COG3266@1|root,COG3266@2|Bacteria,4NKYH@976|Bacteroidetes,1I2JU@117743|Flavobacteriia	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3889749_0	1317122.ATO12_02280	0.0	1010.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1HX6S@117743|Flavobacteriia,2YJAM@290174|Aquimarina	976|Bacteroidetes	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
TLS3_k127_3889749_2	1408473.JHXO01000006_gene1129	1.904e-49	197.0	COG3211@1|root,COG4935@1|root,COG3211@2|Bacteria,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,2G16U@200643|Bacteroidia	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
TLS3_k127_3889749_5	1267211.KI669560_gene354	4.073e-27	113.0	COG2963@1|root,COG2963@2|Bacteria,4NZDV@976|Bacteroidetes	976|Bacteroidetes	L	PFAM transposase IS3 IS911 family protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
TLS3_k127_3889749_1	1267211.KI669560_gene315	2.334e-71	249.0	COG2801@1|root,COG2801@2|Bacteria,4NI3F@976|Bacteroidetes	976|Bacteroidetes	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
TLS3_k127_3934420_1	1237149.C900_05718	1.539e-168	550.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47N25@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
TLS3_k127_3934420_0	1313421.JHBV01000041_gene3505	6.975e-266	864.0	COG3291@1|root,COG3291@2|Bacteria,4NG09@976|Bacteroidetes,1J102@117747|Sphingobacteriia	976|Bacteroidetes	S	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
TLS3_k127_3934420_3	1313421.JHBV01000028_gene1857	1.961e-98	362.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
TLS3_k127_3934420_2	517418.Ctha_0304	8.63e-112	368.0	COG0427@1|root,COG0427@2|Bacteria,1FDQ1@1090|Chlorobi	1090|Chlorobi	C	PFAM acetyl-CoA hydrolase transferase	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
TLS3_k127_3942026_2	1123277.KB893217_gene4490	3.634e-41	157.0	COG0454@1|root,COG0456@2|Bacteria,4NQVT@976|Bacteroidetes,47QAW@768503|Cytophagia	976|Bacteroidetes	K	PFAM GCN5-related N-acetyltransferase	paiA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
TLS3_k127_3942026_1	153721.MYP_1410	3.055e-108	361.0	COG0859@1|root,COG0859@2|Bacteria,4PKBY@976|Bacteroidetes,47NHC@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
TLS3_k127_3942026_0	755732.Fluta_0384	7.542e-320	1007.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NUDC@976|Bacteroidetes,1I7JN@117743|Flavobacteriia,2PA5J@246874|Cryomorphaceae	976|Bacteroidetes	Q	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_3942078_2	755732.Fluta_0143	6.434e-83	279.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,1HWMK@117743|Flavobacteriia,2PA91@246874|Cryomorphaceae	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
TLS3_k127_3942078_1	755732.Fluta_0152	3.003e-186	595.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1HXV2@117743|Flavobacteriia,2PAEP@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
TLS3_k127_3942078_0	929556.Solca_2733	8.181e-195	616.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,1IQY7@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_3942078_4	1122176.KB903537_gene1608	1.467e-16	95.0	COG2931@1|root,COG3210@1|root,COG5184@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,RCC1,RCC1_2
TLS3_k127_3942078_3	926562.Oweho_3478	8.021e-63	247.0	COG3291@1|root,COG3291@2|Bacteria,4NJQN@976|Bacteroidetes,1I7QH@117743|Flavobacteriia	976|Bacteroidetes	O	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,IgGFc_binding,PKD,SprB
TLS3_k127_3952947_0	755732.Fluta_3619	1.616e-133	433.0	COG0036@1|root,COG0517@1|root,COG0036@2|Bacteria,COG0517@2|Bacteria,4PBW2@976|Bacteroidetes,1ICPN@117743|Flavobacteriia,2PBIW@246874|Cryomorphaceae	976|Bacteroidetes	G	Ribulose-phosphate 3 epimerase family	-	-	-	-	-	-	-	-	-	-	-	-	Ribul_P_3_epim
TLS3_k127_3952947_1	755732.Fluta_3618	1.34e-84	284.0	COG2876@1|root,COG2876@2|Bacteria,4NH82@976|Bacteroidetes,1I8SQ@117743|Flavobacteriia,2PARW@246874|Cryomorphaceae	976|Bacteroidetes	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
TLS3_k127_397722_1	1107311.Q767_02430	5.519e-55	210.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,4PPGH@976|Bacteroidetes,1IKM5@117743|Flavobacteriia,2NW1I@237|Flavobacterium	976|Bacteroidetes	O	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_397722_4	1123037.AUDE01000009_gene1434	1.778e-05	53.0	2CE81@1|root,32RZB@2|Bacteria,4NSJP@976|Bacteroidetes,1I46K@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_397722_2	1250005.PHEL85_0456	1.56e-38	150.0	COG2365@1|root,COG2365@2|Bacteria,4NQ5E@976|Bacteroidetes,1I4TZ@117743|Flavobacteriia	976|Bacteroidetes	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase2,Y_phosphatase3
TLS3_k127_397722_3	926556.Echvi_3891	1.328e-30	136.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_397722_0	755732.Fluta_3986	3.639e-122	401.0	COG0612@1|root,COG0612@2|Bacteria,4NEE4@976|Bacteroidetes,1I83S@117743|Flavobacteriia,2PBJ4@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_4006543_5	926562.Oweho_2782	7.119e-19	88.0	COG2274@1|root,COG2274@2|Bacteria,4NFJF@976|Bacteroidetes,1HWYH@117743|Flavobacteriia,2PBEV@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
TLS3_k127_4006543_0	485917.Phep_1425	4.726e-170	542.0	COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,1INWU@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
TLS3_k127_4006543_4	755732.Fluta_4024	2.003e-29	121.0	COG1765@1|root,COG1765@2|Bacteria,4NNTY@976|Bacteroidetes,1I275@117743|Flavobacteriia,2PB4A@246874|Cryomorphaceae	976|Bacteroidetes	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
TLS3_k127_4006543_2	509635.N824_10175	1.734e-33	134.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1ISKN@117747|Sphingobacteriia	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
TLS3_k127_4006543_3	504728.K649_00125	3.587e-30	125.0	COG2391@1|root,COG2391@2|Bacteria,1WK5Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
TLS3_k127_4006543_1	755732.Fluta_4025	6.87e-138	450.0	COG0460@1|root,COG0460@2|Bacteria,4NHRC@976|Bacteroidetes,1HZK9@117743|Flavobacteriia,2PBPU@246874|Cryomorphaceae	976|Bacteroidetes	E	Homoserine dehydrogenase, NAD binding domain	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
TLS3_k127_4013421_16	755732.Fluta_1839	6.654e-91	301.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1I7EW@117743|Flavobacteriia,2PBJ8@246874|Cryomorphaceae	976|Bacteroidetes	F	CobB/CobQ-like glutamine amidotransferase domain	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
TLS3_k127_4013421_21	1408433.JHXV01000019_gene1922	4.012e-53	190.0	COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,1I1Y4@117743|Flavobacteriia,2PAZZ@246874|Cryomorphaceae	976|Bacteroidetes	T	Molecular chaperone DnaK	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
TLS3_k127_4013421_18	755732.Fluta_1721	9.509e-85	287.0	COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,1HYAA@117743|Flavobacteriia,2PB6Y@246874|Cryomorphaceae	976|Bacteroidetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
TLS3_k127_4013421_2	755732.Fluta_1586	1.282e-194	623.0	COG4773@1|root,COG4773@2|Bacteria,4PKTX@976|Bacteroidetes,1HXIR@117743|Flavobacteriia,2PB19@246874|Cryomorphaceae	976|Bacteroidetes	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
TLS3_k127_4013421_1	755732.Fluta_1587	3.709e-292	929.0	COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,1HX2D@117743|Flavobacteriia,2PAE6@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
TLS3_k127_4013421_17	755732.Fluta_1588	5.781e-87	294.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1HY06@117743|Flavobacteriia,2PAPT@246874|Cryomorphaceae	976|Bacteroidetes	D	ATPases associated with a variety of cellular activities	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
TLS3_k127_4013421_12	755732.Fluta_1318	2.568e-114	379.0	COG3823@1|root,COG3823@2|Bacteria,4NF2M@976|Bacteroidetes,1HY29@117743|Flavobacteriia,2PAYW@246874|Cryomorphaceae	976|Bacteroidetes	O	Glutamine cyclotransferase	-	-	2.3.2.5	ko:K00683	-	-	-	-	ko00000,ko01000	-	-	-	Glu_cyclase_2
TLS3_k127_4013421_30	592029.DDD_3029	2.067e-25	110.0	COG3118@1|root,COG3118@2|Bacteria,4NSE6@976|Bacteroidetes,1I47G@117743|Flavobacteriia,3HKFF@363408|Nonlabens	976|Bacteroidetes	O	Protein of unknown function (DUF2847)	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
TLS3_k127_4013421_4	755732.Fluta_1320	1.099e-165	530.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,1HWWV@117743|Flavobacteriia,2PAHY@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
TLS3_k127_4013421_27	755732.Fluta_1322	4.35e-29	120.0	2A5H4@1|root,30U7A@2|Bacteria,4PFFN@976|Bacteroidetes,1IMTB@117743|Flavobacteriia,2PC40@246874|Cryomorphaceae	755732.Fluta_1322|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4013421_7	1237149.C900_03983	3.841e-135	447.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,47JYX@768503|Cytophagia	976|Bacteroidetes	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
TLS3_k127_4013421_13	755732.Fluta_1219	1.476e-105	347.0	COG3298@1|root,COG3298@2|Bacteria,4NECH@976|Bacteroidetes,1HY85@117743|Flavobacteriia,2PATH@246874|Cryomorphaceae	976|Bacteroidetes	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
TLS3_k127_4013421_19	483215.BACFIN_05117	1.967e-65	226.0	COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,2FS26@200643|Bacteroidia,4AQQT@815|Bacteroidaceae	976|Bacteroidetes	T	Psort location Cytoplasmic, score 8.96	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
TLS3_k127_4013421_22	1408433.JHXV01000014_gene3607	3.42e-50	198.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1HWU2@117743|Flavobacteriia,2PB1X@246874|Cryomorphaceae	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
TLS3_k127_4013421_9	755732.Fluta_1222	4.085e-119	394.0	COG0392@1|root,COG0392@2|Bacteria,4NIWG@976|Bacteroidetes,1IHMQ@117743|Flavobacteriia,2PBIY@246874|Cryomorphaceae	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
TLS3_k127_4013421_15	755732.Fluta_1304	2.736e-94	320.0	COG0457@1|root,COG0457@2|Bacteria,4PJHB@976|Bacteroidetes,1IMQ8@117743|Flavobacteriia,2PB7I@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
TLS3_k127_4013421_11	755732.Fluta_1893	6.463e-115	379.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes	976|Bacteroidetes	I	protein CHP03519, membrane, Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_4013421_0	755732.Fluta_1892	0.0	1260.0	COG1520@1|root,COG2312@1|root,COG4386@1|root,COG1520@2|Bacteria,COG2312@2|Bacteria,COG4386@2|Bacteria,4PP0J@976|Bacteroidetes	976|Bacteroidetes	E	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD
TLS3_k127_4013421_31	755732.Fluta_1891	8.993e-22	100.0	2DGVM@1|root,2ZXFN@2|Bacteria,4P8FH@976|Bacteroidetes,1IMT9@117743|Flavobacteriia,2PC3X@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4013421_26	755732.Fluta_1890	6.82e-31	130.0	2AFQ6@1|root,315RZ@2|Bacteria,4PJXZ@976|Bacteroidetes,1IMQA@117743|Flavobacteriia,2PB7X@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
TLS3_k127_4013421_23	755732.Fluta_1636	6.01e-45	172.0	2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,1I2XD@117743|Flavobacteriia,2PB8J@246874|Cryomorphaceae	976|Bacteroidetes	S	GldH lipoprotein	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	GldH_lipo
TLS3_k127_4013421_3	755732.Fluta_1637	4.041e-188	596.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1HXPY@117743|Flavobacteriia,2PA4Y@246874|Cryomorphaceae	976|Bacteroidetes	S	PSP1 C-terminal conserved region	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
TLS3_k127_4013421_6	755732.Fluta_1639	2.198e-141	457.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,1HXGT@117743|Flavobacteriia,2PAMT@246874|Cryomorphaceae	976|Bacteroidetes	L	TIGRFAM DNA polymerase III, delta' subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
TLS3_k127_4013421_14	755732.Fluta_1558	5.745e-96	323.0	COG0697@1|root,COG0697@2|Bacteria,4NE8D@976|Bacteroidetes,1HXCW@117743|Flavobacteriia,2PAVB@246874|Cryomorphaceae	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_4013421_8	1121887.AUDK01000008_gene1203	1.382e-134	452.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1ICYX@117743|Flavobacteriia,2NW87@237|Flavobacterium	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
TLS3_k127_4013421_20	313606.M23134_05213	4.547e-64	232.0	arCOG09742@1|root,2ZBGR@2|Bacteria,4NRNU@976|Bacteroidetes,47V53@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4013421_10	755732.Fluta_1556	1.998e-116	380.0	COG0589@1|root,COG0589@2|Bacteria,4NWVX@976|Bacteroidetes,1IMR1@117743|Flavobacteriia,2PBIA@246874|Cryomorphaceae	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_4013421_38	1341155.FSS13T_10000	7.515e-06	57.0	COG2197@1|root,COG2197@2|Bacteria,4NR5M@976|Bacteroidetes,1HYNZ@117743|Flavobacteriia,2NX0F@237|Flavobacterium	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_3
TLS3_k127_4013421_33	1008457.BAEX01000005_gene952	4.474e-13	72.0	2ET6A@1|root,33KQC@2|Bacteria,4NYA0@976|Bacteroidetes,1IBA5@117743|Flavobacteriia,47J63@76831|Myroides	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4013421_37	313606.M23134_07736	2.512e-08	63.0	2ECA3@1|root,32QV4@2|Bacteria,4NRYD@976|Bacteroidetes,47QR1@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4013421_29	1121930.AQXG01000007_gene413	4.264e-26	116.0	COG2197@1|root,COG2197@2|Bacteria,4NQNY@976|Bacteroidetes,1IY32@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_4013421_5	1408433.JHXV01000032_gene1133	9.214e-145	475.0	COG1807@1|root,COG1807@2|Bacteria,4PG9X@976|Bacteroidetes,1IMRA@117743|Flavobacteriia,2PBNI@246874|Cryomorphaceae	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_4013421_25	742726.HMPREF9448_00738	1.183e-31	136.0	COG0729@1|root,COG1520@1|root,COG0729@2|Bacteria,COG1520@2|Bacteria,4NVBC@976|Bacteroidetes,2FTDT@200643|Bacteroidia,22YG7@171551|Porphyromonadaceae	976|Bacteroidetes	M	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
TLS3_k127_4013421_34	1463821.JOGR01000004_gene2571	1.576e-12	77.0	COG2273@1|root,COG2273@2|Bacteria,2GJQP@201174|Actinobacteria,4EZIJ@85014|Glycomycetales	201174|Actinobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16,RicinB_lectin_2,Ricin_B_lectin
TLS3_k127_4017822_4	1237149.C900_04326	1.138e-124	422.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia	976|Bacteroidetes	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
TLS3_k127_4017822_13	755732.Fluta_2886	2.587e-52	198.0	29Y6Q@1|root,30K08@2|Bacteria,4PCCQ@976|Bacteroidetes,1ICTK@117743|Flavobacteriia,2PC48@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4017822_2	755732.Fluta_2944	2.975e-275	868.0	2C8ZH@1|root,33YQE@2|Bacteria,4P4N5@976|Bacteroidetes,1ICQC@117743|Flavobacteriia,2PBQ9@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4017822_3	755732.Fluta_2943	2.51e-150	489.0	COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,1HWXU@117743|Flavobacteriia,2PACX@246874|Cryomorphaceae	976|Bacteroidetes	L	UvrD-like helicase C-terminal domain	recD2_2	-	3.1.11.5	ko:K01144	-	-	-	-	ko00000,ko01000	-	-	-	AAA_30,UvrD_C_2
TLS3_k127_4017822_21	547042.BACCOPRO_02465	8.368e-06	57.0	2C0G9@1|root,310GM@2|Bacteria,4NHU0@976|Bacteroidetes,2FN0C@200643|Bacteroidia,4AKKG@815|Bacteroidaceae	976|Bacteroidetes	S	COG NOG19144 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4017822_18	1408433.JHXV01000001_gene1008	4.288e-22	106.0	2BRIQ@1|root,32KHQ@2|Bacteria,4PFJ6@976|Bacteroidetes,1IGA1@117743|Flavobacteriia,2PC3P@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF3822)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3822
TLS3_k127_4017822_14	755732.Fluta_2941	2.692e-52	190.0	COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,1I185@117743|Flavobacteriia,2PAZT@246874|Cryomorphaceae	976|Bacteroidetes	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
TLS3_k127_4017822_15	1168289.AJKI01000011_gene604	4.545e-48	176.0	COG0669@1|root,COG0669@2|Bacteria,4NM84@976|Bacteroidetes,2FT6A@200643|Bacteroidia,3XJ2D@558415|Marinilabiliaceae	976|Bacteroidetes	H	Cytidylyltransferase-like	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
TLS3_k127_4017822_6	755732.Fluta_2939	4.719e-121	404.0	COG0526@1|root,COG0526@2|Bacteria,4NNSW@976|Bacteroidetes,1ICQA@117743|Flavobacteriia,2PBPX@246874|Cryomorphaceae	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_8
TLS3_k127_4017822_8	1408433.JHXV01000001_gene1031	4.218e-80	271.0	COG0778@1|root,COG0778@2|Bacteria,4NMUE@976|Bacteroidetes,1I1BE@117743|Flavobacteriia,2PB0W@246874|Cryomorphaceae	976|Bacteroidetes	C	Nitroreductase family	ydjA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
TLS3_k127_4017822_16	755732.Fluta_2937	2.889e-46	176.0	2BPRN@1|root,32IIX@2|Bacteria,4PEDZ@976|Bacteroidetes,1ICSQ@117743|Flavobacteriia,2PC0H@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4017822_1	1313421.JHBV01000046_gene256	3.328e-283	887.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1INWZ@117747|Sphingobacteriia	976|Bacteroidetes	EU	peptidase S9 prolyl oligopeptidase active site domain protein	pop	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
TLS3_k127_4017822_9	1313421.JHBV01000029_gene2007	4.396e-77	265.0	2DBF0@1|root,2Z8VT@2|Bacteria,4NECW@976|Bacteroidetes	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	1.3.1.22	ko:K12343	ko00140,map00140	-	R02208,R02497,R08954,R10242	RC00145	ko00000,ko00001,ko01000	-	-	-	Steroid_dh
TLS3_k127_4017822_7	1122176.KB903542_gene403	1.172e-87	295.0	COG3361@1|root,COG3361@2|Bacteria,4NITY@976|Bacteroidetes,1IRF6@117747|Sphingobacteriia	976|Bacteroidetes	S	conserved protein (COG2071)	-	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
TLS3_k127_4017822_10	1116472.MGMO_20c00270	5.756e-77	273.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,1RMNS@1236|Gammaproteobacteria,1XDKP@135618|Methylococcales	1236|Gammaproteobacteria	C	Tryptophan halogenase	pltM	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
TLS3_k127_4017822_17	926562.Oweho_0227	7.1e-43	173.0	COG1020@1|root,COG1020@2|Bacteria	2|Bacteria	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	AATase,Condensation,FAD_binding_3
TLS3_k127_4017822_11	880073.Calab_2558	9.65e-63	229.0	2BWJ3@1|root,2Z7IQ@2|Bacteria	2|Bacteria	S	PFAM Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
TLS3_k127_4017822_5	153721.MYP_191	4.473e-124	428.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,47MWA@768503|Cytophagia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_4017822_20	240302.BN982_00310	6.303e-08	63.0	COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,4ISBD@91061|Bacilli,3NDY5@45667|Halobacillus	91061|Bacilli	S	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_4017822_12	1454007.JAUG01000127_gene348	1.865e-52	198.0	COG3064@1|root,COG3064@2|Bacteria,4NM6Q@976|Bacteroidetes,1IQNW@117747|Sphingobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_4017822_0	755732.Fluta_0526	1.786e-294	908.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,1HY71@117743|Flavobacteriia,2PAMI@246874|Cryomorphaceae	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
TLS3_k127_4017822_23	1235803.C825_02385	0.0004641	51.0	29AXF@1|root,2ZXWK@2|Bacteria,4P8VZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_4017822_22	1121373.KB903643_gene3523	0.0001207	47.0	2ACBE@1|root,2ZT9S@2|Bacteria,4P862@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4028174_0	1313421.JHBV01000031_gene1536	1.984e-96	322.0	COG1262@1|root,COG1262@2|Bacteria,4NF01@976|Bacteroidetes	976|Bacteroidetes	H	sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_23
TLS3_k127_4028174_2	1313421.JHBV01000009_gene4114	2.421e-54	204.0	COG0189@1|root,COG0189@2|Bacteria,4NEDY@976|Bacteroidetes,1IQ2I@117747|Sphingobacteriia	976|Bacteroidetes	HJM	Belongs to the MurCDEF family	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,RimK
TLS3_k127_4028174_4	755732.Fluta_1137	9.777e-37	145.0	2A9C2@1|root,30YH0@2|Bacteria,4PCAK@976|Bacteroidetes,1ICT4@117743|Flavobacteriia,2PC2E@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4028174_1	755732.Fluta_1138	5.157e-68	235.0	COG0212@1|root,COG0212@2|Bacteria,4NM97@976|Bacteroidetes,1I19B@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
TLS3_k127_4028174_5	211165.AJLN01000153_gene718	4.465e-05	50.0	COG0718@1|root,COG0718@2|Bacteria,1G6TX@1117|Cyanobacteria,1JIQG@1189|Stigonemataceae	1117|Cyanobacteria	S	YbaB/EbfC DNA-binding family	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
TLS3_k127_4028174_3	755732.Fluta_0610	6.991e-54	195.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1HXMD@117743|Flavobacteriia,2PAYC@246874|Cryomorphaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4040598_1	1408433.JHXV01000005_gene2292	1.536e-79	271.0	COG2746@1|root,COG2746@2|Bacteria,4NWN7@976|Bacteroidetes,1I525@117743|Flavobacteriia,2PBE1@246874|Cryomorphaceae	976|Bacteroidetes	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
TLS3_k127_4040598_0	1121904.ARBP01000018_gene2658	3.388e-157	498.0	COG0447@1|root,COG0447@2|Bacteria,4NDXT@976|Bacteroidetes,47JYS@768503|Cytophagia	976|Bacteroidetes	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
TLS3_k127_4049798_1	1353276.JADR01000003_gene2759	3.957e-62	216.0	COG0590@1|root,COG0590@2|Bacteria,4NNJ2@976|Bacteroidetes,1I17S@117743|Flavobacteriia	976|Bacteroidetes	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
TLS3_k127_4049798_0	755732.Fluta_1314	1.671e-70	258.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
TLS3_k127_4049798_3	929703.KE386491_gene883	5.869e-05	48.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,47JRR@768503|Cytophagia	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
TLS3_k127_4068826_3	553177.CAPSP0001_0089	3.031e-10	60.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1HWVX@117743|Flavobacteriia,1ER19@1016|Capnocytophaga	976|Bacteroidetes	H	citrate synthase	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
TLS3_k127_4068826_0	1168034.FH5T_09315	4.885e-66	233.0	COG2135@1|root,COG2135@2|Bacteria,4NI3T@976|Bacteroidetes,2FQ1G@200643|Bacteroidia	976|Bacteroidetes	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
TLS3_k127_4068826_1	1408433.JHXV01000017_gene1563	3.069e-65	239.0	COG3920@1|root,COG3920@2|Bacteria,4NEMC@976|Bacteroidetes,1HZHX@117743|Flavobacteriia,2PBKM@246874|Cryomorphaceae	976|Bacteroidetes	T	HWE histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_2
TLS3_k127_4068826_2	616991.JPOO01000003_gene2159	1.178e-19	91.0	COG0702@1|root,COG0702@2|Bacteria,4NG89@976|Bacteroidetes,1I18P@117743|Flavobacteriia,23H4Q@178469|Arenibacter	976|Bacteroidetes	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
TLS3_k127_409306_2	755732.Fluta_2174	1.638e-35	139.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes,1HWQR@117743|Flavobacteriia,2PAPK@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	wbpP	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
TLS3_k127_409306_0	1408433.JHXV01000024_gene1487	1.9e-91	316.0	COG2244@1|root,COG2244@2|Bacteria,4NR8U@976|Bacteroidetes,1I4GY@117743|Flavobacteriia,2PBQC@246874|Cryomorphaceae	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
TLS3_k127_409306_1	755732.Fluta_2827	7.069e-60	219.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NIFY@976|Bacteroidetes,1HZH9@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TLS3_k127_414522_2	1189612.A33Q_0016	9.157e-24	104.0	COG0607@1|root,COG0607@2|Bacteria,4NQ61@976|Bacteroidetes,47Q3A@768503|Cytophagia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS3_k127_414522_1	755732.Fluta_3294	1.713e-128	417.0	2BG4X@1|root,33858@2|Bacteria,4NW0E@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
TLS3_k127_414522_0	755732.Fluta_3295	0.0	1104.0	COG4206@1|root,COG4206@2|Bacteria,4PM6D@976|Bacteroidetes,1IN1U@117743|Flavobacteriia	976|Bacteroidetes	H	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_414522_3	517418.Ctha_0609	9.492e-13	79.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,1FEW2@1090|Chlorobi	1090|Chlorobi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12
TLS3_k127_4222815_3	1127134.NOCYR_3842	0.0002564	48.0	COG5416@1|root,COG5416@2|Bacteria,2GQTQ@201174|Actinobacteria,4G32C@85025|Nocardiaceae	201174|Actinobacteria	S	Lipopolysaccharide assembly protein A domain	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
TLS3_k127_4222815_0	1349785.BAUG01000006_gene512	6.195e-21	97.0	COG1403@1|root,COG1403@2|Bacteria,4NZQH@976|Bacteroidetes	976|Bacteroidetes	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4222815_1	1122179.KB890417_gene3270	1.604e-16	89.0	COG3279@1|root,COG3279@2|Bacteria,4NKXC@976|Bacteroidetes,1ITHP@117747|Sphingobacteriia	976|Bacteroidetes	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_4222815_4	870187.Thini_2445	0.0005214	50.0	COG0457@1|root,COG0498@1|root,COG1192@1|root,COG4995@1|root,COG0457@2|Bacteria,COG0498@2|Bacteria,COG1192@2|Bacteria,COG4995@2|Bacteria,1ND01@1224|Proteobacteria,1SXEZ@1236|Gammaproteobacteria,4639I@72273|Thiotrichales	72273|Thiotrichales	DE	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,NB-ARC,TIR_2,TPR_12
TLS3_k127_422774_7	1190606.AJYG01000084_gene3264	2.484e-17	92.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,1XVRY@135623|Vibrionales	135623|Vibrionales	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_422774_0	755732.Fluta_1370	4.859e-299	924.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1HXY4@117743|Flavobacteriia,2PABR@246874|Cryomorphaceae	976|Bacteroidetes	J	PFAM tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
TLS3_k127_422774_6	313603.FB2170_15693	9.268e-46	168.0	COG3324@1|root,COG3324@2|Bacteria,4NMFV@976|Bacteroidetes,1IGP1@117743|Flavobacteriia,2PITX@252356|Maribacter	976|Bacteroidetes	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS3_k127_422774_4	1484460.JSWG01000008_gene1994	1.113e-98	327.0	COG2378@1|root,COG2378@2|Bacteria,4NHIC@976|Bacteroidetes,1HZ87@117743|Flavobacteriia	976|Bacteroidetes	K	DNA-binding protein	yobV	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
TLS3_k127_422774_1	755732.Fluta_0108	2.659e-133	445.0	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,4NQ3X@976|Bacteroidetes	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Lectin_legB,PKD
TLS3_k127_422774_2	755732.Fluta_0109	2.046e-114	378.0	COG1609@1|root,COG1609@2|Bacteria,4NESN@976|Bacteroidetes,1IG4Q@117743|Flavobacteriia,2PBTC@246874|Cryomorphaceae	976|Bacteroidetes	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3,Peripla_BP_4
TLS3_k127_422774_3	755732.Fluta_1573	4.05e-114	373.0	COG4783@1|root,COG4783@2|Bacteria,4PKN7@976|Bacteroidetes,1IJEQ@117743|Flavobacteriia,2PARI@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TLS3_k127_422774_8	755732.Fluta_1776	1.258e-14	79.0	COG0671@1|root,COG0671@2|Bacteria,4NPUG@976|Bacteroidetes	976|Bacteroidetes	I	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
TLS3_k127_4229269_3	755732.Fluta_0384	2.483e-22	98.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NUDC@976|Bacteroidetes,1I7JN@117743|Flavobacteriia,2PA5J@246874|Cryomorphaceae	976|Bacteroidetes	Q	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_4229269_2	755732.Fluta_0385	7.819e-124	409.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1HWQI@117743|Flavobacteriia,2PBHP@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_4229269_0	755732.Fluta_0386	7.937e-187	592.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia,2PBHC@246874|Cryomorphaceae	976|Bacteroidetes	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_4229269_1	755732.Fluta_0387	7.58e-153	488.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,1HYHD@117743|Flavobacteriia,2PABG@246874|Cryomorphaceae	976|Bacteroidetes	S	FMN-dependent dehydrogenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
TLS3_k127_4229585_2	755732.Fluta_1407	1.139e-70	245.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1HX2X@117743|Flavobacteriia,2PA59@246874|Cryomorphaceae	976|Bacteroidetes	P	MgtE intracellular N domain	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
TLS3_k127_4229585_1	755732.Fluta_1408	1.873e-75	273.0	COG3307@1|root,COG3307@2|Bacteria,4PBYP@976|Bacteroidetes,1IMS1@117743|Flavobacteriia,2PBUF@246874|Cryomorphaceae	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
TLS3_k127_4229585_0	1408433.JHXV01000040_gene1523	2.767e-156	510.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,1HYZ4@117743|Flavobacteriia,2PAII@246874|Cryomorphaceae	976|Bacteroidetes	M	PDZ domain (Also known as DHR or GLGF)	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
TLS3_k127_4229585_3	755732.Fluta_1410	2.342e-24	107.0	COG0594@1|root,COG0594@2|Bacteria,4P9UN@976|Bacteroidetes,1IGHR@117743|Flavobacteriia,2PB8T@246874|Cryomorphaceae	976|Bacteroidetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
TLS3_k127_4229585_4	755732.Fluta_1185	2.762e-16	79.0	2BJE2@1|root,32DQD@2|Bacteria,4NXW4@976|Bacteroidetes,1IED9@117743|Flavobacteriia,2PB7E@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
TLS3_k127_4232923_1	1392490.JHZX01000001_gene3209	2.289e-58	220.0	COG3209@1|root,COG3391@1|root,COG5492@1|root,COG3209@2|Bacteria,COG3391@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,SprB
TLS3_k127_4232923_2	1406840.Q763_11525	1.464e-55	206.0	COG0223@1|root,COG0223@2|Bacteria,4NT42@976|Bacteroidetes,1I7ZR@117743|Flavobacteriia,2NVV3@237|Flavobacterium	976|Bacteroidetes	J	Formyl transferase, C-terminal domain	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
TLS3_k127_4232923_0	700598.Niako_1051	5.157e-103	347.0	COG0683@1|root,COG0683@2|Bacteria,4NP2T@976|Bacteroidetes,1IU58@117747|Sphingobacteriia	976|Bacteroidetes	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
TLS3_k127_4232923_5	1406840.Q763_11505	1.04e-43	165.0	COG4675@1|root,COG4675@2|Bacteria,4NQJR@976|Bacteroidetes,1I31T@117743|Flavobacteriia,2NX1Q@237|Flavobacterium	976|Bacteroidetes	S	PFAM phage Tail Collar domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
TLS3_k127_4232923_3	1116472.MGMO_180c00020	1.749e-47	176.0	COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,1S64Y@1236|Gammaproteobacteria,1XFRZ@135618|Methylococcales	135618|Methylococcales	S	PFAM Phage Tail Collar	-	-	-	-	-	-	-	-	-	-	-	-	Collar
TLS3_k127_4232923_4	1406840.Q763_11505	3.015e-47	176.0	COG4675@1|root,COG4675@2|Bacteria,4NQJR@976|Bacteroidetes,1I31T@117743|Flavobacteriia,2NX1Q@237|Flavobacterium	976|Bacteroidetes	S	PFAM phage Tail Collar domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
TLS3_k127_4251914_5	1408433.JHXV01000007_gene2922	6.929e-26	119.0	28N0G@1|root,2ZB6W@2|Bacteria,4NF76@976|Bacteroidetes,1I3ZK@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4251914_2	1122176.KB903552_gene3684	1.472e-77	278.0	2CE4Q@1|root,2Z7WX@2|Bacteria,4PNC7@976|Bacteroidetes,1J17R@117747|Sphingobacteriia	976|Bacteroidetes	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4251914_3	755732.Fluta_3299	4.121e-53	196.0	COG0526@1|root,COG0526@2|Bacteria,4NZHV@976|Bacteroidetes,1IAZB@117743|Flavobacteriia	976|Bacteroidetes	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TLS3_k127_4251914_4	1249975.JQLP01000005_gene1099	8.236e-40	154.0	COG0346@1|root,COG0346@2|Bacteria,4PPEK@976|Bacteroidetes,1IKJQ@117743|Flavobacteriia	976|Bacteroidetes	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4251914_1	755732.Fluta_1176	2.002e-171	542.0	COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,1HX4Q@117743|Flavobacteriia,2PACN@246874|Cryomorphaceae	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
TLS3_k127_4251914_0	755732.Fluta_1177	0.0	1054.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1HXYZ@117743|Flavobacteriia,2PAMC@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Cytochrome C and Quinol oxidase polypeptide I	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
TLS3_k127_4368447_0	755732.Fluta_0192	1.229e-81	277.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,1HX5T@117743|Flavobacteriia,2PAWW@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Shikimate dehydrogenase substrate binding domain	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
TLS3_k127_4368447_1	1286632.P278_18150	5.323e-74	255.0	COG2035@1|root,COG2035@2|Bacteria,4NFKI@976|Bacteroidetes,1HYAC@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
TLS3_k127_443504_0	402612.FP1586	4.535e-165	527.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HXKS@117743|Flavobacteriia,2NYN1@237|Flavobacterium	976|Bacteroidetes	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
TLS3_k127_443504_2	1406840.Q763_09675	3.284e-47	175.0	COG2318@1|root,COG2318@2|Bacteria,4NMXH@976|Bacteroidetes,1I32M@117743|Flavobacteriia	976|Bacteroidetes	S	Damage-inducible protein DinB	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_443504_1	402612.FP1587	6.968e-82	275.0	COG1309@1|root,COG1309@2|Bacteria,4NNK5@976|Bacteroidetes,1I8ZD@117743|Flavobacteriia,2NUT3@237|Flavobacterium	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
TLS3_k127_4443070_2	1305836.AXVE01000006_gene456	4.57e-05	55.0	COG5276@1|root,COG5276@2|Bacteria,1UUVN@1239|Firmicutes,4HBJX@91061|Bacilli,26E03@186818|Planococcaceae	91061|Bacilli	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
TLS3_k127_4443070_0	755732.Fluta_0505	7.823e-242	755.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,1HXNP@117743|Flavobacteriia,2PAFF@246874|Cryomorphaceae	976|Bacteroidetes	I	PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
TLS3_k127_4443070_1	755732.Fluta_0506	2.854e-232	763.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWKQ@117743|Flavobacteriia,2PA5P@246874|Cryomorphaceae	976|Bacteroidetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	-	-	-	-	-	-	-	-	-	TamB
TLS3_k127_4467910_5	1408433.JHXV01000005_gene2414	2.967e-41	166.0	COG0457@1|root,COG0457@2|Bacteria,4PJV3@976|Bacteroidetes,1ICAX@117743|Flavobacteriia,2PB8P@246874|Cryomorphaceae	976|Bacteroidetes	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4467910_2	1121957.ATVL01000014_gene1459	2.156e-56	213.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4467910_0	755732.Fluta_3334	0.0	1005.0	COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,1HXPG@117743|Flavobacteriia,2PAMJ@246874|Cryomorphaceae	976|Bacteroidetes	J	Ribosomal protein S1-like RNA-binding domain	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
TLS3_k127_4467910_6	1313421.JHBV01000029_gene1882	9.702e-20	105.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CUB,MAM,PKD,P_proprotein,fn3
TLS3_k127_4467910_3	153721.MYP_3548	1.353e-51	207.0	COG3858@1|root,COG3858@2|Bacteria,4NJZ6@976|Bacteroidetes,47QYP@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl hydrolases family 18	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Glyco_hydro_18,Laminin_G_3
TLS3_k127_4467910_4	755732.Fluta_3516	6.233e-50	180.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,1I21X@117743|Flavobacteriia,2PB48@246874|Cryomorphaceae	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_4467910_1	755732.Fluta_3463	1.703e-79	269.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1HXJ6@117743|Flavobacteriia,2PAN4@246874|Cryomorphaceae	976|Bacteroidetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
TLS3_k127_4496695_1	1492738.FEM21_08610	3.595e-76	259.0	COG2318@1|root,COG2318@2|Bacteria,4NNQI@976|Bacteroidetes,1I28A@117743|Flavobacteriia,2NTF8@237|Flavobacterium	976|Bacteroidetes	S	DinB superfamily	yfiT	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_4496695_4	926562.Oweho_0743	2.204e-37	145.0	COG4891@1|root,COG4891@2|Bacteria,4NQ7V@976|Bacteroidetes,1I37K@117743|Flavobacteriia,2PBUH@246874|Cryomorphaceae	976|Bacteroidetes	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_4496695_2	926556.Echvi_1125	1.739e-60	214.0	COG0664@1|root,COG0664@2|Bacteria,4NIP0@976|Bacteroidetes,47PQT@768503|Cytophagia	976|Bacteroidetes	T	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
TLS3_k127_4496695_0	1296415.JACC01000039_gene4010	2.001e-90	306.0	COG0500@1|root,COG2226@2|Bacteria,4NG68@976|Bacteroidetes,1I0VV@117743|Flavobacteriia	976|Bacteroidetes	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_4496695_3	1313421.JHBV01000016_gene5388	3.419e-48	177.0	COG0520@1|root,COG0520@2|Bacteria,4NJEQ@976|Bacteroidetes	976|Bacteroidetes	E	Aminotransferase, class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
TLS3_k127_4535969_5	1408433.JHXV01000029_gene3082	7.291e-17	82.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1HXQF@117743|Flavobacteriia,2PA4F@246874|Cryomorphaceae	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
TLS3_k127_4535969_2	755732.Fluta_0942	8.808e-69	240.0	2BBSK@1|root,32XPV@2|Bacteria,4NSW3@976|Bacteroidetes,1IKDA@117743|Flavobacteriia,2PB42@246874|Cryomorphaceae	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_4535969_0	755732.Fluta_0943	5.945e-255	792.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,1HWYC@117743|Flavobacteriia,2PAB5@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
TLS3_k127_4535969_1	755732.Fluta_0944	1.467e-254	801.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,1HXI1@117743|Flavobacteriia,2PAM4@246874|Cryomorphaceae	976|Bacteroidetes	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
TLS3_k127_4535969_3	1408433.JHXV01000002_gene356	5.584e-39	156.0	COG0760@1|root,COG0760@2|Bacteria,4PK4P@976|Bacteroidetes,1IEB5@117743|Flavobacteriia,2PC5K@246874|Cryomorphaceae	976|Bacteroidetes	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4535969_4	1408433.JHXV01000002_gene355	3.705e-27	114.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1HXTE@117743|Flavobacteriia,2PA5V@246874|Cryomorphaceae	976|Bacteroidetes	M	PPIC-type PPIASE domain	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
TLS3_k127_4564374_0	755732.Fluta_0945	4.92e-98	330.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1HXTE@117743|Flavobacteriia,2PA5V@246874|Cryomorphaceae	976|Bacteroidetes	M	PPIC-type PPIASE domain	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
TLS3_k127_4564374_1	755732.Fluta_0946	2.814e-38	144.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HXA1@117743|Flavobacteriia,2PA5W@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TLS3_k127_457785_0	1450525.JATV01000002_gene1958	5.906e-228	715.0	COG1680@1|root,COG1680@2|Bacteria,4NHRA@976|Bacteroidetes,1HYSZ@117743|Flavobacteriia,2NSWM@237|Flavobacterium	976|Bacteroidetes	V	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF4440
TLS3_k127_457785_2	926559.JoomaDRAFT_3484	2.831e-65	227.0	COG3620@1|root,COG3620@2|Bacteria,4NM67@976|Bacteroidetes,1I1NT@117743|Flavobacteriia	976|Bacteroidetes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870,HTH_3
TLS3_k127_457785_1	1121007.AUML01000015_gene3968	4.588e-71	244.0	COG0431@1|root,COG0431@2|Bacteria,4NQ3Y@976|Bacteroidetes,1I2TM@117743|Flavobacteriia	976|Bacteroidetes	S	FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
TLS3_k127_457785_3	1250005.PHEL85_1275	3.111e-29	117.0	2E32V@1|root,32Y33@2|Bacteria,4NWGB@976|Bacteroidetes,1I5F2@117743|Flavobacteriia,3VXDK@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4578769_1	755732.Fluta_2255	1.953e-242	754.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1HWJZ@117743|Flavobacteriia,2PAEB@246874|Cryomorphaceae	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_4578769_0	755732.Fluta_2267	7.577e-266	835.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,1HXNJ@117743|Flavobacteriia,2PAJT@246874|Cryomorphaceae	976|Bacteroidetes	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
TLS3_k127_4578769_9	755732.Fluta_2266	6.442e-45	171.0	2A95D@1|root,30Y9V@2|Bacteria,4PC1D@976|Bacteroidetes,1IMSW@117743|Flavobacteriia,2PC1G@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4578769_8	1408433.JHXV01000009_gene1314	3.517e-45	170.0	COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,1I1XH@117743|Flavobacteriia,2PB0Q@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
TLS3_k127_4578769_6	755732.Fluta_2264	5.207e-53	189.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,1IMRK@117743|Flavobacteriia,2PBRK@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
TLS3_k127_4578769_7	755732.Fluta_2263	2.431e-52	190.0	2AAU0@1|root,3106Q@2|Bacteria,4NNSV@976|Bacteroidetes,1ICQH@117743|Flavobacteriia,2PBRJ@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4578769_5	269798.CHU_0788	7.421e-54	206.0	COG5263@1|root,COG5263@2|Bacteria,4NJ6B@976|Bacteroidetes,47PRU@768503|Cytophagia	976|Bacteroidetes	KLT	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
TLS3_k127_4578769_2	1406840.Q763_03540	3.985e-75	260.0	COG2230@1|root,COG2230@2|Bacteria,4PKDE@976|Bacteroidetes,1HWWC@117743|Flavobacteriia,2NTK3@237|Flavobacterium	976|Bacteroidetes	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31,TehB
TLS3_k127_4578769_4	755732.Fluta_2261	3.655e-64	228.0	COG0428@1|root,COG0428@2|Bacteria,4NG1R@976|Bacteroidetes,1HYRJ@117743|Flavobacteriia,2PB10@246874|Cryomorphaceae	976|Bacteroidetes	P	ZIP Zinc transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
TLS3_k127_4578769_10	1313301.AUGC01000006_gene17	2.289e-29	126.0	COG0671@1|root,COG0671@2|Bacteria,4NV5Q@976|Bacteroidetes	976|Bacteroidetes	I	Pfam PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
TLS3_k127_4578769_3	755732.Fluta_2194	5.1e-74	252.0	COG2148@1|root,COG2148@2|Bacteria,4NNHR@976|Bacteroidetes,1I2JE@117743|Flavobacteriia,2PBKW@246874|Cryomorphaceae	976|Bacteroidetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
TLS3_k127_4594794_0	755732.Fluta_3800	0.0	1030.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1HY43@117743|Flavobacteriia,2PA8Y@246874|Cryomorphaceae	976|Bacteroidetes	T	PFAM Elongation factor Tu domain 2	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
TLS3_k127_4594794_1	755732.Fluta_3801	6.628e-200	634.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1HWMB@117743|Flavobacteriia,2PAJU@246874|Cryomorphaceae	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
TLS3_k127_4616642_3	1408433.JHXV01000008_gene224	4.02e-103	343.0	COG0668@1|root,COG0668@2|Bacteria,4NHU7@976|Bacteroidetes,1I0RF@117743|Flavobacteriia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
TLS3_k127_4616642_0	755732.Fluta_0211	0.0	1209.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1HXDT@117743|Flavobacteriia,2PAFM@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
TLS3_k127_4616642_2	926549.KI421517_gene3879	6.619e-117	389.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,47P7K@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
TLS3_k127_4616642_6	755732.Fluta_0228	5.495e-43	170.0	COG3103@1|root,COG4991@2|Bacteria,4P67T@976|Bacteroidetes,1IA3H@117743|Flavobacteriia	976|Bacteroidetes	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4616642_4	755732.Fluta_0228	5.775e-56	207.0	COG3103@1|root,COG4991@2|Bacteria,4P67T@976|Bacteroidetes,1IA3H@117743|Flavobacteriia	976|Bacteroidetes	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4616642_5	755732.Fluta_0226	1.071e-50	192.0	COG3103@1|root,COG4991@2|Bacteria,4P67T@976|Bacteroidetes,1IA3H@117743|Flavobacteriia	2|Bacteria	T	sh3 domain protein	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	Cu_amine_oxidN1,SH3_3
TLS3_k127_4616642_7	880071.Fleli_0804	5.405e-26	112.0	COG2259@1|root,31BQE@2|Bacteria,4NQH2@976|Bacteroidetes,47SDX@768503|Cytophagia	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
TLS3_k127_4616642_1	755732.Fluta_0230	2.878e-207	649.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWRZ@117743|Flavobacteriia,2PABM@246874|Cryomorphaceae	976|Bacteroidetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
TLS3_k127_4622535_0	755732.Fluta_3630	0.0	1250.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,1HXI7@117743|Flavobacteriia,2PA8B@246874|Cryomorphaceae	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
TLS3_k127_4622535_1	1122179.KB890413_gene4698	4.163e-118	385.0	2DBBI@1|root,2Z888@2|Bacteria,4NQB6@976|Bacteroidetes	976|Bacteroidetes	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	YHYH
TLS3_k127_4656547_1	755732.Fluta_0895	6.742e-91	302.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1HX0U@117743|Flavobacteriia,2PAC8@246874|Cryomorphaceae	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
TLS3_k127_4656547_2	755732.Fluta_0894	1.627e-68	249.0	2A79G@1|root,30W62@2|Bacteria,4P9IB@976|Bacteroidetes,1IFW7@117743|Flavobacteriia,2PB8Y@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
TLS3_k127_4656547_0	755732.Fluta_0893	8.265e-119	387.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,1HXJZ@117743|Flavobacteriia,2PAE7@246874|Cryomorphaceae	976|Bacteroidetes	G	Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
TLS3_k127_4666248_4	755732.Fluta_2335	2.488e-62	220.0	COG2981@1|root,COG2981@2|Bacteria,4NHXY@976|Bacteroidetes,1HXWD@117743|Flavobacteriia,2PBQT@246874|Cryomorphaceae	976|Bacteroidetes	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
TLS3_k127_4666248_1	755732.Fluta_2334	3.233e-142	464.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,4PP0P@976|Bacteroidetes,1ICNJ@117743|Flavobacteriia,2PBBD@246874|Cryomorphaceae	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
TLS3_k127_4666248_0	1168034.FH5T_10945	6.744e-225	716.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,2FM68@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
TLS3_k127_4666248_2	313628.LNTAR_03749	2.059e-79	274.0	COG0248@1|root,COG0248@2|Bacteria	2|Bacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
TLS3_k127_4666248_3	755732.Fluta_2308	8.88e-79	270.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,1HWVP@117743|Flavobacteriia,2PAVZ@246874|Cryomorphaceae	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
TLS3_k127_4666248_5	1121957.ATVL01000014_gene1459	5.036e-45	185.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4666248_6	926562.Oweho_2108	9.105e-12	78.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,1HYZP@117743|Flavobacteriia,2PBG6@246874|Cryomorphaceae	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,PKD
TLS3_k127_4701905_3	755732.Fluta_0251	4.334e-61	223.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,1HY6K@117743|Flavobacteriia,2PBI4@246874|Cryomorphaceae	976|Bacteroidetes	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
TLS3_k127_4701905_1	179408.Osc7112_2624	3.964e-92	314.0	COG1619@1|root,COG1619@2|Bacteria,1G059@1117|Cyanobacteria,1H7XC@1150|Oscillatoriales	1117|Cyanobacteria	V	microcin C7 resistance	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
TLS3_k127_4701905_4	755732.Fluta_0299	1.181e-49	184.0	2A9AU@1|root,30YFU@2|Bacteria,4PC99@976|Bacteroidetes,1IMST@117743|Flavobacteriia,2PC18@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4701905_0	755732.Fluta_0300	3.504e-156	511.0	COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,1IKD1@117743|Flavobacteriia,2PAST@246874|Cryomorphaceae	976|Bacteroidetes	A	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
TLS3_k127_4701905_2	755732.Fluta_0301	2.956e-62	216.0	COG0524@1|root,COG0524@2|Bacteria,4NFJ9@976|Bacteroidetes,1HY55@117743|Flavobacteriia,2PAF2@246874|Cryomorphaceae	976|Bacteroidetes	G	pfkB family carbohydrate kinase	ydjH	-	-	-	-	-	-	-	-	-	-	-	PfkB
TLS3_k127_4726386_0	1131812.JQMS01000001_gene2386	0.0	1009.0	COG0745@1|root,COG4251@1|root,COG5278@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,COG5278@2|Bacteria,4NFBM@976|Bacteroidetes,1HYZJ@117743|Flavobacteriia,2NTFR@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
TLS3_k127_4726386_1	153721.MYP_373	6.428e-134	436.0	COG3437@1|root,COG4251@1|root,COG3437@2|Bacteria,COG4251@2|Bacteria,4NDUQ@976|Bacteroidetes,47PTN@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
TLS3_k127_4726386_2	1173028.ANKO01000056_gene2161	5.225e-81	290.0	COG0745@1|root,COG2202@1|root,COG4251@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG4251@2|Bacteria,1G2QC@1117|Cyanobacteria,1H7Q7@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_4726386_3	580332.Slit_1329	1.006e-55	198.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,2WGQ0@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
TLS3_k127_4726386_4	1124780.ANNU01000013_gene3813	4.483e-55	208.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,4NG0Y@976|Bacteroidetes,47JUV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
TLS3_k127_4726386_6	1304284.L21TH_1860	1.187e-08	66.0	COG3394@1|root,COG3394@2|Bacteria,1V3MB@1239|Firmicutes,24IMA@186801|Clostridia,36G15@31979|Clostridiaceae	186801|Clostridia	G	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
TLS3_k127_4726386_5	471854.Dfer_4541	5.982e-24	111.0	COG1572@1|root,COG2353@1|root,COG1572@2|Bacteria,COG2353@2|Bacteria,4NFAX@976|Bacteroidetes,47K9M@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,ILEI,Peptidase_C25
TLS3_k127_4726386_8	391598.FBBAL38_01530	2.453e-05	55.0	COG1572@1|root,COG3210@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes	976|Bacteroidetes	H	Gliding motility-associated C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,P_proprotein,SprB
TLS3_k127_4729333_0	755732.Fluta_2285	1.547e-298	929.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,4NF9S@976|Bacteroidetes,1HX5E@117743|Flavobacteriia,2PAFH@246874|Cryomorphaceae	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
TLS3_k127_4735536_5	755732.Fluta_0172	8.109e-93	307.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,1HWX6@117743|Flavobacteriia,2PASU@246874|Cryomorphaceae	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
TLS3_k127_4735536_6	471854.Dfer_4645	4.309e-59	211.0	COG4430@1|root,COG4430@2|Bacteria,4NNH0@976|Bacteroidetes,47PYG@768503|Cytophagia	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
TLS3_k127_4735536_1	929556.Solca_0699	8.596e-201	634.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,1IQSD@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
TLS3_k127_4735536_4	755732.Fluta_0176	4.464e-109	357.0	COG0463@1|root,COG0463@2|Bacteria,4PM68@976|Bacteroidetes,1IJKP@117743|Flavobacteriia,2PANZ@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
TLS3_k127_4735536_3	755732.Fluta_0177	1.786e-136	448.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia,2PBD3@246874|Cryomorphaceae	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,MAM,TSP_3,fn3
TLS3_k127_4735536_0	755732.Fluta_2379	3.573e-277	872.0	COG4953@1|root,COG4953@2|Bacteria,4NEG5@976|Bacteroidetes,1HWRT@117743|Flavobacteriia,2PBET@246874|Cryomorphaceae	976|Bacteroidetes	M	Penicillin-Binding Protein C-terminus Family	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
TLS3_k127_4735536_2	755732.Fluta_2380	2.736e-196	637.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia,2PBHB@246874|Cryomorphaceae	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,Reg_prop,Y_Y_Y
TLS3_k127_4744540_0	984262.SGRA_2555	7.36e-159	511.0	COG3405@1|root,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_15,CHU_C
TLS3_k127_4744540_1	1237149.C900_00596	2.02e-150	486.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,47KP4@768503|Cytophagia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS3_k127_4751108_6	1279009.ADICEAN_03608	8.658e-05	49.0	2FCAI@1|root,344E6@2|Bacteria,4P5IR@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4751108_3	755732.Fluta_2555	9.326e-105	351.0	COG0156@1|root,COG0156@2|Bacteria,4NEXI@976|Bacteroidetes,1HY28@117743|Flavobacteriia,2PANW@246874|Cryomorphaceae	976|Bacteroidetes	H	PFAM Aminotransferase class I and II	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_4751108_1	755732.Fluta_2554	4.476e-202	632.0	COG0502@1|root,COG0502@2|Bacteria,4NEMA@976|Bacteroidetes,1HX6M@117743|Flavobacteriia,2PA6R@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
TLS3_k127_4751108_4	755732.Fluta_2552	6.731e-67	231.0	COG0245@1|root,COG0245@2|Bacteria,4NP0N@976|Bacteroidetes,1ICQ5@117743|Flavobacteriia,2PBP5@246874|Cryomorphaceae	976|Bacteroidetes	I	YgbB family	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
TLS3_k127_4751108_2	755732.Fluta_2551	7.136e-147	477.0	COG2067@1|root,COG2067@2|Bacteria,4NDZW@976|Bacteroidetes,1HY15@117743|Flavobacteriia,2PA6Z@246874|Cryomorphaceae	976|Bacteroidetes	I	long-chain fatty acid transport protein	porV	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4751108_0	755732.Fluta_2550	0.0	1211.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1HYJD@117743|Flavobacteriia,2PAHV@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
TLS3_k127_4751108_5	1408433.JHXV01000001_gene1084	4.673e-06	49.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1HZRC@117743|Flavobacteriia,2PANF@246874|Cryomorphaceae	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_4761000_0	755732.Fluta_3906	6.481e-168	541.0	COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes,1HYNG@117743|Flavobacteriia,2PA9X@246874|Cryomorphaceae	976|Bacteroidetes	E	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
TLS3_k127_4761000_1	869213.JCM21142_72591	3e-112	365.0	COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,47MGG@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
TLS3_k127_4761000_2	755732.Fluta_3891	4.108e-76	258.0	COG0009@1|root,COG0009@2|Bacteria,4NM43@976|Bacteroidetes,1HZTW@117743|Flavobacteriia,2PBUR@246874|Cryomorphaceae	976|Bacteroidetes	J	Telomere recombination	rimN	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
TLS3_k127_4761000_3	391625.PPSIR1_41039	1.115e-45	177.0	COG0596@1|root,COG0596@2|Bacteria,1QZUA@1224|Proteobacteria,43CPD@68525|delta/epsilon subdivisions,2X7WR@28221|Deltaproteobacteria,2Z3IZ@29|Myxococcales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_4768457_2	755732.Fluta_2328	5.732e-07	51.0	COG0745@1|root,COG0745@2|Bacteria,4NM5Q@976|Bacteroidetes,1I1SA@117743|Flavobacteriia,2PBHX@246874|Cryomorphaceae	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_4768457_3	41431.PCC8801_3110	8.166e-06	53.0	2FARY@1|root,342ZC@2|Bacteria,1GEIJ@1117|Cyanobacteria,3KIG2@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4768457_1	755732.Fluta_2329	3.357e-77	264.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,1HYB1@117743|Flavobacteriia,2PAXA@246874|Cryomorphaceae	976|Bacteroidetes	O	Glycoprotease family	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
TLS3_k127_4768457_0	755732.Fluta_2331	2.105e-86	288.0	COG2876@1|root,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1HX6I@117743|Flavobacteriia,2PAIH@246874|Cryomorphaceae	976|Bacteroidetes	E	Chorismate mutase type II	aroF	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
TLS3_k127_4770463_1	485913.Krac_0132	1.956e-20	105.0	COG3505@1|root,COG3505@2|Bacteria	2|Bacteria	U	unidirectional conjugation	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf
TLS3_k127_4770463_2	1107311.Q767_15695	2.335e-07	65.0	COG2304@1|root,COG3291@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia,2P0KQ@237|Flavobacterium	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gal_Lectin,HYR,Laminin_G_3,PKD,SprB,TSP_3
TLS3_k127_4770463_0	153721.MYP_2988	1.47e-141	504.0	COG3188@1|root,COG3291@1|root,COG3188@2|Bacteria,COG3291@2|Bacteria,4NHVA@976|Bacteroidetes,47MA8@768503|Cytophagia	976|Bacteroidetes	NU	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PA14
TLS3_k127_4793641_8	755732.Fluta_0018	2.587e-31	127.0	COG3391@1|root,COG3391@2|Bacteria,4NESV@976|Bacteroidetes,1HY4U@117743|Flavobacteriia,2PBQ3@246874|Cryomorphaceae	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4793641_3	641526.ADIWIN_0656	3.895e-80	278.0	COG3291@1|root,COG3794@1|root,COG3291@2|Bacteria,COG3794@2|Bacteria,4NJ39@976|Bacteroidetes,1HZRK@117743|Flavobacteriia	976|Bacteroidetes	L	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Beta_helix,DUF4465
TLS3_k127_4793641_4	153721.MYP_2343	9.885e-69	239.0	COG0500@1|root,COG0500@2|Bacteria,4NNNE@976|Bacteroidetes,47Q1Z@768503|Cytophagia	976|Bacteroidetes	Q	Thiopurine S-methyltransferase (TPMT)	tpm	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
TLS3_k127_4793641_5	755732.Fluta_2595	2.939e-52	192.0	COG3047@1|root,COG3047@2|Bacteria,4NEAU@976|Bacteroidetes,1HYKC@117743|Flavobacteriia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
TLS3_k127_4793641_6	1121890.AUDO01000007_gene2488	2.786e-46	174.0	COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,1I2RJ@117743|Flavobacteriia,2NUQ6@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
TLS3_k127_4793641_2	755732.Fluta_3597	2.378e-96	319.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,1HX3G@117743|Flavobacteriia,2PAMW@246874|Cryomorphaceae	976|Bacteroidetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
TLS3_k127_4793641_1	755732.Fluta_3596	1.091e-130	428.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,1HX17@117743|Flavobacteriia,2PA8E@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
TLS3_k127_4793641_0	755732.Fluta_3595	3.76e-135	437.0	COG0111@1|root,COG0111@2|Bacteria,4NDVN@976|Bacteroidetes,1HWXS@117743|Flavobacteriia,2PAJN@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TLS3_k127_4793641_7	755732.Fluta_3594	4.332e-43	159.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,1HYNV@117743|Flavobacteriia,2PAKZ@246874|Cryomorphaceae	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
TLS3_k127_479858_2	926562.Oweho_2105	6.219e-113	380.0	COG3291@1|root,COG3291@2|Bacteria,4PMDA@976|Bacteroidetes,1IKH7@117743|Flavobacteriia,2PC60@246874|Cryomorphaceae	976|Bacteroidetes	E	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
TLS3_k127_479858_6	1408433.JHXV01000002_gene334	8.017e-25	119.0	COG2374@1|root,COG4935@1|root,COG2374@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,LTD,SLH
TLS3_k127_479858_7	1313421.JHBV01000039_gene2674	3.841e-20	106.0	COG1075@1|root,COG4935@1|root,COG1075@2|Bacteria,COG4935@2|Bacteria,4P5ZV@976|Bacteroidetes,1IZT8@117747|Sphingobacteriia	2|Bacteria	O	acetyltransferases and hydrolases with the alpha beta hydrolase fold	est	-	-	-	-	-	-	-	-	-	-	-	DUF2779,DUF676,LCAT,PGAP1
TLS3_k127_479858_5	1313421.JHBV01000029_gene1882	2.423e-43	179.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CUB,MAM,PKD,P_proprotein,fn3
TLS3_k127_479858_1	755732.Fluta_2513	6.355e-127	414.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,1HYKY@117743|Flavobacteriia,2PA9U@246874|Cryomorphaceae	976|Bacteroidetes	M	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
TLS3_k127_479858_4	755732.Fluta_0279	6.611e-53	189.0	COG2050@1|root,COG2050@2|Bacteria,4NNYG@976|Bacteroidetes,1I2BT@117743|Flavobacteriia,2PB6T@246874|Cryomorphaceae	976|Bacteroidetes	Q	Thioesterase superfamily	ydiI	-	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT,Hydrolase_3
TLS3_k127_479858_3	755732.Fluta_0278	3.178e-61	224.0	COG1169@1|root,COG1169@2|Bacteria,4NF6U@976|Bacteroidetes,1HX5V@117743|Flavobacteriia,2PAV1@246874|Cryomorphaceae	976|Bacteroidetes	HQ	chorismate binding enzyme	entC	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
TLS3_k127_479858_0	1408433.JHXV01000026_gene3019	7.517e-140	463.0	COG1165@1|root,COG1165@2|Bacteria,4NETZ@976|Bacteroidetes,1HXR0@117743|Flavobacteriia,2PAKA@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
TLS3_k127_479858_8	755732.Fluta_0275	3.831e-17	84.0	COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,1HXRT@117743|Flavobacteriia,2PBQ8@246874|Cryomorphaceae	976|Bacteroidetes	P	Membrane protein TerC, possibly involved in tellurium resistance	terC	-	-	-	-	-	-	-	-	-	-	-	TerC
TLS3_k127_4804863_6	755732.Fluta_2027	1.425e-62	221.0	COG0634@1|root,COG0634@2|Bacteria,4NNIB@976|Bacteroidetes,1I22T@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
TLS3_k127_4804863_2	755732.Fluta_2026	1.227e-128	423.0	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,1HXZB@117743|Flavobacteriia,2PAGB@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
TLS3_k127_4804863_0	755732.Fluta_2025	7.22e-252	828.0	COG2202@1|root,COG2208@1|root,COG3292@1|root,COG2202@2|Bacteria,COG2208@2|Bacteria,COG3292@2|Bacteria,4NK8Q@976|Bacteroidetes	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GerE,HATPase_c,Reg_prop,SpoIIE,Y_Y_Y
TLS3_k127_4804863_8	1313301.AUGC01000005_gene284	1.449e-41	156.0	COG0720@1|root,COG0720@2|Bacteria,4NNIS@976|Bacteroidetes	976|Bacteroidetes	H	Pfam 6-pyruvoyl tetrahydropterin synthase	ygcM	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
TLS3_k127_4804863_4	1408433.JHXV01000022_gene3168	2.425e-93	317.0	COG1524@1|root,COG1524@2|Bacteria,4PKSD@976|Bacteroidetes,1IJEH@117743|Flavobacteriia	976|Bacteroidetes	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme,Phosphodiest
TLS3_k127_4804863_5	1408433.JHXV01000018_gene3793	1.674e-67	238.0	COG3770@1|root,COG3770@2|Bacteria,4P2DE@976|Bacteroidetes	976|Bacteroidetes	M	Penicillin-insensitive murein endopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M74
TLS3_k127_4804863_7	755732.Fluta_1939	2.556e-58	204.0	COG4068@1|root,COG4068@2|Bacteria,4NQ3Z@976|Bacteroidetes,1I2T2@117743|Flavobacteriia,2PB51@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
TLS3_k127_4804863_1	1408433.JHXV01000030_gene1394	9.471e-143	461.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HWNM@117743|Flavobacteriia,2PAIU@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TLS3_k127_4804863_3	714943.Mucpa_6107	1.643e-109	362.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,1IR6K@117747|Sphingobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TLS3_k127_4804863_9	755732.Fluta_1944	1.632e-12	77.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,1HY3G@117743|Flavobacteriia,2PBA6@246874|Cryomorphaceae	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4811654_0	755732.Fluta_3512	3.153e-123	407.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1HXFD@117743|Flavobacteriia,2PBBE@246874|Cryomorphaceae	976|Bacteroidetes	O	Subtilase family	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_4811654_1	755732.Fluta_3513	3.149e-93	315.0	COG1404@1|root,COG1404@2|Bacteria,4NTWX@976|Bacteroidetes,1I4GV@117743|Flavobacteriia,2PBAJ@246874|Cryomorphaceae	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_4818612_2	1517682.HW49_07615	1.876e-53	197.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,2FM3H@200643|Bacteroidia,22XPT@171551|Porphyromonadaceae	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
TLS3_k127_4818612_0	755732.Fluta_0126	8.02e-86	293.0	COG0697@1|root,COG0697@2|Bacteria,4NDYH@976|Bacteroidetes,1HXMM@117743|Flavobacteriia,2PAR1@246874|Cryomorphaceae	976|Bacteroidetes	EG	EamA-like transporter family	sam	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
TLS3_k127_4818612_1	755732.Fluta_0127	7.403e-57	199.0	COG1721@1|root,COG1721@2|Bacteria,4NG0C@976|Bacteroidetes,1HXKI@117743|Flavobacteriia,2PAFJ@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TLS3_k127_4824988_0	1117318.PRUB_13261	3.027e-150	499.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,1RQUU@1236|Gammaproteobacteria,2Q23H@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
TLS3_k127_4824988_1	1117318.PRUB_13256	1.031e-49	181.0	2B9U6@1|root,32372@2|Bacteria,1RHAQ@1224|Proteobacteria,1S2IH@1236|Gammaproteobacteria,2Q3K2@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
TLS3_k127_4824988_2	1278073.MYSTI_05997	1.858e-10	67.0	2DMQT@1|root,32T2H@2|Bacteria,1N211@1224|Proteobacteria,42U4F@68525|delta/epsilon subdivisions,2WQNK@28221|Deltaproteobacteria,2Z2AW@29|Myxococcales	28221|Deltaproteobacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
TLS3_k127_4864546_2	616991.JPOO01000001_gene4611	2.496e-106	353.0	COG0598@1|root,COG0598@2|Bacteria,4NG3C@976|Bacteroidetes,1HXRX@117743|Flavobacteriia,23H33@178469|Arenibacter	976|Bacteroidetes	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
TLS3_k127_4864546_1	755732.Fluta_2314	3.095e-132	427.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1HWPM@117743|Flavobacteriia,2PA55@246874|Cryomorphaceae	976|Bacteroidetes	V	TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_4864546_0	755732.Fluta_2310	6.037e-195	615.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1HY1I@117743|Flavobacteriia,2PAHP@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
TLS3_k127_4864546_3	1313421.JHBV01000028_gene1857	7.997e-25	116.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
TLS3_k127_4884129_5	755732.Fluta_0707	1.329e-126	439.0	COG3291@1|root,COG5549@1|root,COG3291@2|Bacteria,COG5549@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2PBDM@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
TLS3_k127_4884129_2	755732.Fluta_2251	6.122e-167	527.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,1HXXW@117743|Flavobacteriia,2PADK@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
TLS3_k127_4884129_11	755732.Fluta_2248	8.34e-43	161.0	COG1764@1|root,COG1764@2|Bacteria	2|Bacteria	O	response to oxidative stress	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
TLS3_k127_4884129_6	755732.Fluta_2247	5.564e-91	308.0	COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,1HX8Z@117743|Flavobacteriia,2PAPX@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
TLS3_k127_4884129_9	755732.Fluta_2239	2.368e-65	233.0	COG1011@1|root,COG1011@2|Bacteria,4NM66@976|Bacteroidetes,1I188@117743|Flavobacteriia,2PAUK@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	yjjG	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
TLS3_k127_4884129_10	755732.Fluta_2238	2.904e-49	179.0	2EVWW@1|root,33PAJ@2|Bacteria,4NZKD@976|Bacteroidetes,1ICSC@117743|Flavobacteriia,2PBZN@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4884129_7	755732.Fluta_2237	6.732e-90	300.0	COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,1HX32@117743|Flavobacteriia,2PBNQ@246874|Cryomorphaceae	976|Bacteroidetes	F	Uracil phosphoribosyltransferase	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
TLS3_k127_4884129_1	755732.Fluta_2236	1.526e-239	754.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1HY1E@117743|Flavobacteriia,2PA6E@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
TLS3_k127_4884129_4	755732.Fluta_2235	1.303e-136	439.0	COG0715@1|root,COG0715@2|Bacteria,4NETN@976|Bacteroidetes,1HYVJ@117743|Flavobacteriia,2PATK@246874|Cryomorphaceae	976|Bacteroidetes	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
TLS3_k127_4884129_3	755732.Fluta_2256	6.23e-152	486.0	COG0276@1|root,COG0276@2|Bacteria,4NE83@976|Bacteroidetes,1HXUV@117743|Flavobacteriia,2PAT3@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
TLS3_k127_4884129_0	755732.Fluta_2226	2.47e-254	788.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,1HWQ7@117743|Flavobacteriia,2PAEN@246874|Cryomorphaceae	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
TLS3_k127_4884129_8	755732.Fluta_3449	6.673e-78	268.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K03686,ko:K05801,ko:K17867	-	-	-	-	ko00000,ko03012,ko03029,ko03110	-	-	-	DnaJ,TerB
TLS3_k127_4922054_0	1450525.JATV01000012_gene3109	3.444e-277	897.0	COG3513@1|root,COG3513@2|Bacteria,4NFM9@976|Bacteroidetes,1HYZN@117743|Flavobacteriia,2NTXY@237|Flavobacterium	976|Bacteroidetes	L	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer	cas9	-	-	ko:K09952	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH_4
TLS3_k127_4922054_1	1168034.FH5T_17130	6.059e-99	331.0	COG1518@1|root,COG1518@2|Bacteria,4NEKQ@976|Bacteroidetes,2FNDN@200643|Bacteroidia	976|Bacteroidetes	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
TLS3_k127_4922054_2	1168034.FH5T_17135	2.966e-45	166.0	COG3512@1|root,COG3512@2|Bacteria,4NQ8Z@976|Bacteroidetes,2FTHK@200643|Bacteroidia	976|Bacteroidetes	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
TLS3_k127_4931106_0	1313421.JHBV01000138_gene1206	1.749e-142	469.0	COG5295@1|root,COG5295@2|Bacteria,4NF3S@976|Bacteroidetes,1ISQ8@117747|Sphingobacteriia	976|Bacteroidetes	UW	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Peptidase_S74
TLS3_k127_4931106_1	755732.Fluta_0530	1.677e-104	349.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes,1HXSH@117743|Flavobacteriia,2PBE6@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
TLS3_k127_4945334_1	1250005.PHEL85_1115	3.346e-52	188.0	COG0727@1|root,COG0727@2|Bacteria,4P0AN@976|Bacteroidetes,1IMAQ@117743|Flavobacteriia,3VVHF@52959|Polaribacter	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
TLS3_k127_4945334_0	1469557.JSWF01000014_gene2434	0.0	1148.0	COG1032@1|root,COG1032@2|Bacteria,4NETM@976|Bacteroidetes,1HZ18@117743|Flavobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TLS3_k127_4948903_0	755732.Fluta_0296	2.859e-201	653.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HWM8@117743|Flavobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
TLS3_k127_4948903_1	755732.Fluta_0294	9.04e-64	242.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,1HYJH@117743|Flavobacteriia,2PAXR@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4131)	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
TLS3_k127_4948903_2	755732.Fluta_2220	1.647e-49	199.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI9U@976|Bacteroidetes,1HX1I@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_7
TLS3_k127_4953923_1	1313421.JHBV01000007_gene4253	1.191e-183	583.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,1IP0F@117747|Sphingobacteriia	976|Bacteroidetes	S	HI0933 family	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
TLS3_k127_4953923_5	755732.Fluta_0325	1.847e-18	94.0	2A8BJ@1|root,30XD4@2|Bacteria,4PAT3@976|Bacteroidetes,1I6G9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4953923_2	755732.Fluta_2661	2.866e-97	322.0	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,1HXNW@117743|Flavobacteriia,2PASQ@246874|Cryomorphaceae	976|Bacteroidetes	I	Phosphatidylserine decarboxylase	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
TLS3_k127_4953923_3	927658.AJUM01000037_gene2293	2.672e-50	188.0	COG0575@1|root,COG0575@2|Bacteria,4PPXI@976|Bacteroidetes	976|Bacteroidetes	I	Belongs to the CDS family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
TLS3_k127_4953923_0	755732.Fluta_2663	1.035e-265	825.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1HXSC@117743|Flavobacteriia,2PA4Q@246874|Cryomorphaceae	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
TLS3_k127_4972972_0	755732.Fluta_2510	1.541e-215	682.0	COG5010@1|root,COG5010@2|Bacteria,4PMJW@976|Bacteroidetes,1IMQQ@117743|Flavobacteriia,2PBFK@246874|Cryomorphaceae	976|Bacteroidetes	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
TLS3_k127_4972972_9	938709.AUSH02000069_gene1524	2.859e-43	180.0	COG1345@1|root,COG2374@1|root,COG3391@1|root,COG1345@2|Bacteria,COG2374@2|Bacteria,COG3391@2|Bacteria,4NGSK@976|Bacteroidetes	976|Bacteroidetes	N	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
TLS3_k127_4972972_11	926549.KI421517_gene1465	5.696e-15	89.0	COG2353@1|root,COG2353@2|Bacteria,4PNPU@976|Bacteroidetes,47YDS@768503|Cytophagia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4972972_6	755732.Fluta_2305	9.509e-55	203.0	COG0707@1|root,COG0707@2|Bacteria,4NFRJ@976|Bacteroidetes,1HXSS@117743|Flavobacteriia,2PAZW@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
TLS3_k127_4972972_2	755732.Fluta_2300	1.642e-125	403.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,1HWT0@117743|Flavobacteriia,2PA6J@246874|Cryomorphaceae	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
TLS3_k127_4972972_1	755732.Fluta_2301	1.398e-211	663.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,1HXIP@117743|Flavobacteriia,2PAG8@246874|Cryomorphaceae	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
TLS3_k127_4972972_3	755732.Fluta_2303	1.969e-102	336.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,1HXZG@117743|Flavobacteriia,2PAW3@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
TLS3_k127_4972972_7	118163.Ple7327_1389	1.352e-53	203.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gumK	-	2.4.1.264	ko:K07011,ko:K13659	-	-	R09732	RC00005,RC00049	ko00000,ko01000,ko01003	-	GT70	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
TLS3_k127_4972972_4	755732.Fluta_2295	1.074e-100	334.0	2BVTQ@1|root,2Z7J9@2|Bacteria,4NGSY@976|Bacteroidetes,1HWRX@117743|Flavobacteriia,2PAQZ@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF2797)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2797
TLS3_k127_4972972_8	755732.Fluta_2268	7.587e-51	182.0	2AGY9@1|root,3176X@2|Bacteria,4NQD4@976|Bacteroidetes,1I2XZ@117743|Flavobacteriia,2PB71@246874|Cryomorphaceae	976|Bacteroidetes	S	Gliding motility protein GldC	gldC	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4972972_5	755732.Fluta_2269	2.049e-68	244.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,1HYAM@117743|Flavobacteriia,2PB41@246874|Cryomorphaceae	976|Bacteroidetes	O	Gliding motility protein, GldB	gldB	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4972972_10	755732.Fluta_2270	9.802e-20	92.0	29ZH4@1|root,30MGV@2|Bacteria,4PBQQ@976|Bacteroidetes,1ICQS@117743|Flavobacteriia,2PBTA@246874|Cryomorphaceae	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_4973891_4	755732.Fluta_1923	4.592e-39	155.0	COG0810@1|root,COG0810@2|Bacteria,4PKAV@976|Bacteroidetes,1HWXW@117743|Flavobacteriia	976|Bacteroidetes	M	Gliding motility protein RemB	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
TLS3_k127_4973891_1	755732.Fluta_1922	5.938e-80	284.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,1IJNM@117743|Flavobacteriia,2PB2Q@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4973891_0	1408433.JHXV01000005_gene2440	5.967e-152	494.0	COG2067@1|root,COG2067@2|Bacteria,4NRUP@976|Bacteroidetes,1I6RT@117743|Flavobacteriia,2PBC3@246874|Cryomorphaceae	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4973891_7	1121931.AUHG01000017_gene1564	1.897e-26	111.0	COG0629@1|root,COG0629@2|Bacteria,4NNYW@976|Bacteroidetes,1I282@117743|Flavobacteriia	976|Bacteroidetes	L	single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
TLS3_k127_4973891_8	755732.Fluta_0802	1.247e-24	108.0	COG0629@1|root,COG0629@2|Bacteria	2|Bacteria	L	single-stranded DNA binding	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
TLS3_k127_4973891_3	755732.Fluta_0803	8.703e-42	156.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I2UG@117743|Flavobacteriia,2PB27@246874|Cryomorphaceae	976|Bacteroidetes	L	TIGRFAM single stranded DNA-binding protein (ssb)	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
TLS3_k127_4973891_2	755732.Fluta_0087	6.381e-43	177.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2PBEH@246874|Cryomorphaceae	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB,TIG
TLS3_k127_4973891_10	485918.Cpin_4195	0.0001941	54.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K03929,ko:K12287	-	-	-	-	ko00000,ko01000,ko02044	-	CE10	-	Big_5,DUF3494,He_PIG,LVIVD,Laminin_G_3,SLH,TSP_3
TLS3_k127_4973891_6	1223410.KN050846_gene2453	2.793e-31	140.0	COG2866@1|root,COG3291@1|root,COG4886@1|root,COG4935@1|root,COG2866@2|Bacteria,COG3291@2|Bacteria,COG4886@2|Bacteria,COG4935@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gal_Lectin,HYR,Laminin_G_3,PKD,SprB,TSP_3
TLS3_k127_4973891_9	1484460.JSWG01000009_gene697	7.53e-07	58.0	COG1319@1|root,COG4886@1|root,COG1319@2|Bacteria,COG4886@2|Bacteria,4PNJF@976|Bacteroidetes,1HX6N@117743|Flavobacteriia	976|Bacteroidetes	C	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4973891_5	926562.Oweho_2161	1.49e-37	154.0	COG5295@1|root,COG5295@2|Bacteria,4NV9S@976|Bacteroidetes,1ICR8@117743|Flavobacteriia,2PBVB@246874|Cryomorphaceae	976|Bacteroidetes	UW	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5047827_4	742725.HMPREF9450_01363	4.076e-56	197.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,4NMAJ@976|Bacteroidetes,2FNTE@200643|Bacteroidia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
TLS3_k127_5047827_1	755732.Fluta_0618	1.428e-102	343.0	COG0741@1|root,COG0741@2|Bacteria,4P2CQ@976|Bacteroidetes,1ICP7@117743|Flavobacteriia,2PBGK@246874|Cryomorphaceae	976|Bacteroidetes	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
TLS3_k127_5047827_6	266748.HY04_03175	1.251e-32	128.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,1I3W5@117743|Flavobacteriia,3ZS8I@59732|Chryseobacterium	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
TLS3_k127_5047827_0	755732.Fluta_1128	6.028e-275	858.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,1HWMV@117743|Flavobacteriia,2PBAZ@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase family 21	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3
TLS3_k127_5047827_2	1121904.ARBP01000001_gene5509	4.465e-96	319.0	COG0463@1|root,COG0463@2|Bacteria,4PKIQ@976|Bacteroidetes,47YFC@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_5047827_5	1121104.AQXH01000001_gene1153	3.456e-47	178.0	COG3387@1|root,COG3387@2|Bacteria,4NNRV@976|Bacteroidetes	976|Bacteroidetes	G	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
TLS3_k127_5047827_3	755732.Fluta_0608	6.696e-63	218.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,1HXWT@117743|Flavobacteriia,2PAAG@246874|Cryomorphaceae	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
TLS3_k127_5061937_1	755732.Fluta_1077	1.457e-90	320.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia,2PBB7@246874|Cryomorphaceae	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
TLS3_k127_5061937_0	755732.Fluta_1076	8.24e-96	316.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1ICNV@117743|Flavobacteriia,2PBDQ@246874|Cryomorphaceae	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_5112223_0	755732.Fluta_2375	0.0	1104.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,1HWNZ@117743|Flavobacteriia,2PADI@246874|Cryomorphaceae	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
TLS3_k127_5112223_1	755732.Fluta_2374	4.32e-39	146.0	COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,1I3ZI@117743|Flavobacteriia,2PAZ6@246874|Cryomorphaceae	976|Bacteroidetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
TLS3_k127_514021_6	1313421.JHBV01000028_gene1857	5.805e-18	96.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
TLS3_k127_514021_1	1189612.A33Q_4179	2.223e-182	579.0	COG0626@1|root,COG0626@2|Bacteria,4NIV1@976|Bacteroidetes,47P29@768503|Cytophagia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
TLS3_k127_514021_5	755732.Fluta_1415	1.218e-41	158.0	COG1522@1|root,COG1522@2|Bacteria,4NNH2@976|Bacteroidetes,1I2AJ@117743|Flavobacteriia,2PAY5@246874|Cryomorphaceae	976|Bacteroidetes	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
TLS3_k127_514021_0	755732.Fluta_1346	2.039e-231	719.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1HYD3@117743|Flavobacteriia,2PAHT@246874|Cryomorphaceae	976|Bacteroidetes	C	Acyl-CoA dehydrogenase, C-terminal domain	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_514021_2	755732.Fluta_1344	4.619e-127	409.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,1HWMQ@117743|Flavobacteriia,2PA6W@246874|Cryomorphaceae	976|Bacteroidetes	H	Uroporphyrinogen-III synthase HemD	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
TLS3_k127_514021_4	202956.BBNL01000019_gene614	1.496e-90	304.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria,3NKCS@468|Moraxellaceae	1236|Gammaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
TLS3_k127_514021_3	1121889.AUDM01000007_gene930	6.625e-97	339.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.121	ko:K07004,ko:K20755	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Exo_endo_phos,LTD,Omp28,Peptidase_M14
TLS3_k127_5153348_0	616991.JPOO01000003_gene255	1.736e-138	445.0	COG0243@1|root,COG1251@1|root,COG0243@2|Bacteria,COG1251@2|Bacteria,4NG4N@976|Bacteroidetes,1HXQ0@117743|Flavobacteriia,23FWX@178469|Arenibacter	976|Bacteroidetes	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.7.7.2	ko:K00367	ko00910,ko01120,map00910,map01120	M00531	R00791	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,Pyr_redox_2
TLS3_k127_5153348_1	926549.KI421517_gene1981	3.512e-69	241.0	COG3203@1|root,COG3203@2|Bacteria,4NDYW@976|Bacteroidetes,47JMP@768503|Cytophagia	976|Bacteroidetes	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
TLS3_k127_5154898_2	755732.Fluta_1223	3.012e-34	132.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1HXYP@117743|Flavobacteriia,2PA7D@246874|Cryomorphaceae	976|Bacteroidetes	EF	Phosphoribosyl synthetase-associated domain	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
TLS3_k127_5154898_1	755732.Fluta_1224	2.065e-63	223.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,1HWZN@117743|Flavobacteriia,2PAXC@246874|Cryomorphaceae	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
TLS3_k127_5154898_0	755732.Fluta_1225	7.028e-95	329.0	COG3023@1|root,COG3023@2|Bacteria,4NN1U@976|Bacteroidetes	976|Bacteroidetes	V	COGs COG3023 Negative regulator of beta-lactamase expression	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CUB
TLS3_k127_5178103_8	755732.Fluta_1954	2.225e-08	55.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,1HY6A@117743|Flavobacteriia,2PADB@246874|Cryomorphaceae	976|Bacteroidetes	J	tRNA synthetase class II core domain (G, H, P, S and T)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
TLS3_k127_5178103_6	269798.CHU_1932	8.201e-14	81.0	COG2885@1|root,COG2885@2|Bacteria,4NW6U@976|Bacteroidetes,47UYY@768503|Cytophagia	976|Bacteroidetes	M	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,OmpA
TLS3_k127_5178103_2	755732.Fluta_1956	1.843e-189	610.0	COG0457@1|root,COG0457@2|Bacteria,4NE2V@976|Bacteroidetes,1HWRP@117743|Flavobacteriia,2PAI5@246874|Cryomorphaceae	976|Bacteroidetes	S	FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6,TPR_8
TLS3_k127_5178103_3	1121875.KB907549_gene1989	2.869e-77	263.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,1HXRV@117743|Flavobacteriia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA1	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
TLS3_k127_5178103_7	384616.Pisl_0269	3.869e-09	62.0	arCOG00632@1|root,arCOG00632@2157|Archaea	2157|Archaea	P	Domain in cystathionine beta-synthase and other proteins.	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	CBS,MFS_1,Sugar_tr
TLS3_k127_5178103_1	1408433.JHXV01000040_gene1541	5.594e-216	674.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,1HXFK@117743|Flavobacteriia,2PBE7@246874|Cryomorphaceae	976|Bacteroidetes	L	impB/mucB/samB family	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
TLS3_k127_5178103_0	1408433.JHXV01000040_gene1540	0.0	1287.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,1HX66@117743|Flavobacteriia,2PBC4@246874|Cryomorphaceae	976|Bacteroidetes	L	Bacterial DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
TLS3_k127_5178103_5	313606.M23134_03755	1.346e-25	111.0	COG0662@1|root,COG0662@2|Bacteria,4NVCS@976|Bacteroidetes	976|Bacteroidetes	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,MannoseP_isomer
TLS3_k127_5178103_4	984262.SGRA_1386	4.383e-45	175.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF1080,MAM,PKD,SprB,fn3
TLS3_k127_5186144_0	755732.Fluta_2035	1.241e-179	612.0	COG1520@1|root,COG3291@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,4PI0E@976|Bacteroidetes,1IN8R@117743|Flavobacteriia,2PB6P@246874|Cryomorphaceae	976|Bacteroidetes	M	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR
TLS3_k127_5186144_4	755732.Fluta_2034	1.759e-65	236.0	COG2885@1|root,COG2885@2|Bacteria,4PNPK@976|Bacteroidetes	976|Bacteroidetes	M	Pfam:DUF3308	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_5186144_2	755732.Fluta_2033	2.078e-116	389.0	COG0204@1|root,COG0204@2|Bacteria,4NN7X@976|Bacteroidetes,1ICPF@117743|Flavobacteriia,2PBHS@246874|Cryomorphaceae	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TLS3_k127_5186144_6	1408433.JHXV01000001_gene804	3.524e-20	96.0	COG0239@1|root,COG0239@2|Bacteria,4P9SD@976|Bacteroidetes,1IEE9@117743|Flavobacteriia,2PBA2@246874|Cryomorphaceae	976|Bacteroidetes	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
TLS3_k127_5186144_5	755732.Fluta_2030	1.284e-33	136.0	COG0671@1|root,COG0671@2|Bacteria,4NNVQ@976|Bacteroidetes,1I2I3@117743|Flavobacteriia,2PB3W@246874|Cryomorphaceae	976|Bacteroidetes	I	Acid phosphatase homologues	ybjG	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
TLS3_k127_5186144_1	755732.Fluta_2029	4.909e-171	541.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,1HXN1@117743|Flavobacteriia,2PAES@246874|Cryomorphaceae	976|Bacteroidetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
TLS3_k127_5186144_3	755732.Fluta_2028	5.212e-70	241.0	COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,1HWR5@117743|Flavobacteriia,2PAVN@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
TLS3_k127_519057_3	755732.Fluta_2084	6.982e-45	170.0	COG2931@1|root,COG5295@1|root,COG2931@2|Bacteria,COG5295@2|Bacteria,4NF3S@976|Bacteroidetes	976|Bacteroidetes	UW	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Peptidase_S74
TLS3_k127_519057_2	755732.Fluta_2083	1.799e-86	302.0	COG3291@1|root,COG3291@2|Bacteria,4P4C7@976|Bacteroidetes	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
TLS3_k127_519057_0	1313421.JHBV01000042_gene3224	2.531e-198	629.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,1IQI6@117747|Sphingobacteriia	976|Bacteroidetes	Q	COG1233 Phytoene dehydrogenase and related	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
TLS3_k127_519057_1	1313421.JHBV01000042_gene3225	1.184e-103	343.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,1IP80@117747|Sphingobacteriia	976|Bacteroidetes	I	Squalene phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
TLS3_k127_519057_4	1313421.JHBV01000042_gene3228	2.608e-24	104.0	COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,1IT6S@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
TLS3_k127_5234462_3	1296416.JACB01000067_gene19	3.646e-43	173.0	COG3595@1|root,COG3595@2|Bacteria,4NW0T@976|Bacteroidetes,1IJ53@117743|Flavobacteriia,2YHRI@290174|Aquimarina	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
TLS3_k127_5234462_2	755732.Fluta_0307	6.236e-45	169.0	COG1595@1|root,COG1595@2|Bacteria,4P6AG@976|Bacteroidetes,1ICQJ@117743|Flavobacteriia,2PBS0@246874|Cryomorphaceae	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_5234462_1	1218108.KB908292_gene1486	5.143e-74	256.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,1HYAN@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_5234462_0	688270.Celal_4258	6.451e-81	290.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,1HWJQ@117743|Flavobacteriia,1F7RE@104264|Cellulophaga	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_5234462_4	1453500.AT05_04560	0.0004307	52.0	COG2374@1|root,COG3291@1|root,COG2374@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD,PKD,fn3
TLS3_k127_5248502_0	313606.M23134_07734	2.011e-44	169.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,47NAQ@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_5248502_1	1042376.AFPK01000029_gene1574	1.031e-14	82.0	COG4585@1|root,COG4585@2|Bacteria,4NJN6@976|Bacteroidetes,1IFY9@117743|Flavobacteriia,406Z8@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TLS3_k127_5254797_0	1408433.JHXV01000012_gene3868	1.526e-201	632.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HX7B@117743|Flavobacteriia,2PACI@246874|Cryomorphaceae	976|Bacteroidetes	I	Thiolase, C-terminal domain	phbA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
TLS3_k127_5254797_1	760192.Halhy_5476	2.279e-48	185.0	2A3KA@1|root,30S3D@2|Bacteria,4PIYF@976|Bacteroidetes,1IXQP@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5263515_5	1396141.BATP01000062_gene4458	1.62e-08	64.0	COG1082@1|root,COG2730@1|root,COG3119@1|root,COG3250@1|root,COG3533@1|root,COG4733@1|root,COG5297@1|root,COG1082@2|Bacteria,COG2730@2|Bacteria,COG3119@2|Bacteria,COG3250@2|Bacteria,COG3533@2|Bacteria,COG4733@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	AP_endonuc_2,Alginate_lyase,Laminin_G_3,NPCBM
TLS3_k127_5263515_4	929556.Solca_0737	1.407e-20	107.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IR0W@117747|Sphingobacteriia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA
TLS3_k127_5263515_0	761193.Runsl_1846	1.181e-136	450.0	COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes,47MT8@768503|Cytophagia	976|Bacteroidetes	Q	phytoene	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
TLS3_k127_5263515_2	755732.Fluta_2670	3.112e-71	243.0	COG0652@1|root,COG0652@2|Bacteria,4PM5K@976|Bacteroidetes,1IKDZ@117743|Flavobacteriia,2PBRP@246874|Cryomorphaceae	976|Bacteroidetes	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT,HEAT_2,Pro_isomerase
TLS3_k127_5263515_3	269798.CHU_1344	1.065e-30	127.0	2E2N8@1|root,32XRD@2|Bacteria,4NSR6@976|Bacteroidetes,47VN4@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5263515_1	1122226.AUHX01000005_gene2541	4.224e-115	389.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1HXWQ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
TLS3_k127_527101_1	1453505.JASY01000015_gene4440	1.421e-114	372.0	2EE83@1|root,2ZAV7@2|Bacteria,4NKCE@976|Bacteroidetes,1HYB8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_527101_0	755732.Fluta_0654	7.55e-260	818.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,1HX0J@117743|Flavobacteriia,2PADV@246874|Cryomorphaceae	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
TLS3_k127_527101_2	1408433.JHXV01000001_gene940	2.151e-11	64.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,1HWXZ@117743|Flavobacteriia,2PAQ6@246874|Cryomorphaceae	976|Bacteroidetes	S	Predicted permease YjgP/YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
TLS3_k127_5271228_6	755732.Fluta_0269	2.72e-106	351.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1HWJD@117743|Flavobacteriia,2PAFN@246874|Cryomorphaceae	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
TLS3_k127_5271228_0	755732.Fluta_0268	1.056e-234	732.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1HXC5@117743|Flavobacteriia,2PAKV@246874|Cryomorphaceae	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
TLS3_k127_5271228_5	755732.Fluta_0267	4.274e-115	375.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,1HWK9@117743|Flavobacteriia,2PA56@246874|Cryomorphaceae	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
TLS3_k127_5271228_1	755732.Fluta_0265	7.158e-211	664.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,1HX1G@117743|Flavobacteriia,2PAG0@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
TLS3_k127_5271228_4	755732.Fluta_2696	1.457e-134	441.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,1HWME@117743|Flavobacteriia,2PAEH@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM competence damage-inducible protein CinA N-terminal domain	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
TLS3_k127_5271228_7	755732.Fluta_2697	2.333e-37	141.0	COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,1I3YG@117743|Flavobacteriia,2PB6U@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
TLS3_k127_5271228_8	1197477.IA57_09520	2.266e-29	117.0	COG0267@1|root,COG0267@2|Bacteria,4NURM@976|Bacteroidetes,1I55D@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
TLS3_k127_5271228_9	1408433.JHXV01000002_gene328	1.237e-15	77.0	2E359@1|root,31RFA@2|Bacteria,4PJMX@976|Bacteroidetes,1ICTQ@117743|Flavobacteriia,2PC4N@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4295
TLS3_k127_5271228_2	1408433.JHXV01000002_gene327	8.581e-157	499.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,1HX6U@117743|Flavobacteriia,2PA96@246874|Cryomorphaceae	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
TLS3_k127_5271228_3	880071.Fleli_0428	5.305e-152	497.0	COG1404@1|root,COG3227@1|root,COG3291@1|root,COG4386@1|root,COG1404@2|Bacteria,COG3227@2|Bacteria,COG3291@2|Bacteria,COG4386@2|Bacteria,4NGRJ@976|Bacteroidetes,47JD6@768503|Cytophagia	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	fpp2	-	-	-	-	-	-	-	-	-	-	-	Cleaved_Adhesin,PKD,Peptidase_M43
TLS3_k127_528100_2	491205.JARQ01000007_gene3059	6.496e-138	460.0	COG3299@1|root,COG3299@2|Bacteria,4NF69@976|Bacteroidetes,1HYP7@117743|Flavobacteriia,3ZTK3@59732|Chryseobacterium	976|Bacteroidetes	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
TLS3_k127_528100_0	1296415.JACC01000011_gene540	1.114e-268	854.0	COG3422@1|root,COG3422@2|Bacteria,4NHE4@976|Bacteroidetes,1I0UZ@117743|Flavobacteriia,2YHEU@290174|Aquimarina	976|Bacteroidetes	S	double-strand break repair	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_528100_1	388413.ALPR1_12705	2.322e-156	534.0	COG0419@1|root,COG3291@1|root,COG0419@2|Bacteria,COG3291@2|Bacteria,4NI5F@976|Bacteroidetes,47U4G@768503|Cytophagia	976|Bacteroidetes	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,PKD
TLS3_k127_529061_3	755732.Fluta_3377	4.611e-19	87.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,1I191@117743|Flavobacteriia,2PAYM@246874|Cryomorphaceae	976|Bacteroidetes	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
TLS3_k127_529061_1	755732.Fluta_3378	1.584e-34	143.0	COG0484@1|root,COG0484@2|Bacteria,4PCBI@976|Bacteroidetes,1ICTD@117743|Flavobacteriia,2PC3F@246874|Cryomorphaceae	976|Bacteroidetes	O	DnaJ-class molecular chaperone with C-terminal Zn finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
TLS3_k127_529061_0	1380384.JADN01000003_gene904	3.94e-78	273.0	COG0318@1|root,COG0318@2|Bacteria,4NEXK@976|Bacteroidetes,1HX5P@117743|Flavobacteriia	976|Bacteroidetes	IQ	O-succinylbenzoic acid--CoA ligase	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_529061_2	984262.SGRA_2328	1.249e-28	119.0	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,1ISA3@117747|Sphingobacteriia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin,Thioredoxin_2,Thioredoxin_7
TLS3_k127_5301824_3	43989.cce_1519	7.439e-26	123.0	COG2202@1|root,COG2203@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,1G3J0@1117|Cyanobacteria,3KFW5@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
TLS3_k127_5301824_0	1121904.ARBP01000024_gene6621	4.541e-60	228.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria,4P2B2@976|Bacteroidetes,47QWM@768503|Cytophagia	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
TLS3_k127_5301824_2	926562.Oweho_1818	6.706e-37	149.0	COG3279@1|root,COG3279@2|Bacteria,4NNHE@976|Bacteroidetes,1HZAH@117743|Flavobacteriia,2PATW@246874|Cryomorphaceae	976|Bacteroidetes	K	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_5301824_1	1341181.FLJC2902T_22140	7.899e-44	172.0	COG2931@1|root,COG5295@1|root,COG2931@2|Bacteria,COG5295@2|Bacteria,4NF3S@976|Bacteroidetes,1IKUQ@117743|Flavobacteriia,2NXWT@237|Flavobacterium	976|Bacteroidetes	UW	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Peptidase_S74
TLS3_k127_5302722_0	1233951.IO90_14330	1.147e-96	321.0	COG4529@1|root,COG4529@2|Bacteria,4NFKU@976|Bacteroidetes,1HZPU@117743|Flavobacteriia	976|Bacteroidetes	S	FAD-NAD(P)-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_9
TLS3_k127_5302722_1	1392490.JHZX01000001_gene3541	9.893e-85	282.0	2CB8G@1|root,2Z88H@2|Bacteria,4NF68@976|Bacteroidetes,1HYYV@117743|Flavobacteriia	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
TLS3_k127_5310458_2	1185876.BN8_03539	5.797e-10	60.0	COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
TLS3_k127_5310458_0	1094466.KQS_08705	6.421e-294	919.0	COG0475@1|root,COG0475@2|Bacteria,4NFPE@976|Bacteroidetes,1I0V4@117743|Flavobacteriia,2NTIQ@237|Flavobacterium	976|Bacteroidetes	P	Sodium hydrogen exchanger	nhaS3	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
TLS3_k127_5310458_1	269798.CHU_3519	3.218e-79	271.0	COG3279@1|root,COG3279@2|Bacteria,4NE6M@976|Bacteroidetes,47NFF@768503|Cytophagia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_5311237_0	1123242.JH636435_gene2139	3.778e-68	240.0	COG1134@1|root,COG1134@2|Bacteria,2IX6N@203682|Planctomycetes	203682|Planctomycetes	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
TLS3_k127_5311237_4	395961.Cyan7425_0521	7.902e-30	130.0	COG0500@1|root,COG1404@1|root,COG1404@2|Bacteria,COG2226@2|Bacteria,1G2T7@1117|Cyanobacteria	1117|Cyanobacteria	O	Cyanobactin maturation protease, PatA PatG family	acyG	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,Peptidase_S8
TLS3_k127_5311237_3	1174528.JH992898_gene2478	1.001e-32	141.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	strG	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,PhyH,UbiA
TLS3_k127_5311237_1	1279009.ADICEAN_01124	1.173e-57	210.0	COG1682@1|root,COG1682@2|Bacteria,4NF36@976|Bacteroidetes,47NFE@768503|Cytophagia	976|Bacteroidetes	GM	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
TLS3_k127_5311237_2	1150600.ADIARSV_2821	1.2e-41	162.0	COG1216@1|root,COG1216@2|Bacteria,4NIW6@976|Bacteroidetes,1ISRD@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_5325183_2	755732.Fluta_0659	9.25e-109	360.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,1HWXZ@117743|Flavobacteriia,2PAQ6@246874|Cryomorphaceae	976|Bacteroidetes	S	Predicted permease YjgP/YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
TLS3_k127_5325183_0	755732.Fluta_0660	5.499e-195	616.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,1HXAZ@117743|Flavobacteriia,2PABX@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
TLS3_k127_5325183_1	755732.Fluta_0661	2.89e-129	425.0	COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,1HXJW@117743|Flavobacteriia,2PAQQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_5325183_3	755732.Fluta_0662	2.41e-92	306.0	COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes,1I19Q@117743|Flavobacteriia,2PBCD@246874|Cryomorphaceae	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_5325183_4	755732.Fluta_0669	1.374e-88	296.0	COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,1HYFU@117743|Flavobacteriia,2PAQF@246874|Cryomorphaceae	976|Bacteroidetes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
TLS3_k127_5325183_5	755732.Fluta_0691	6.59e-64	224.0	2A21C@1|root,30QBC@2|Bacteria,4PGY1@976|Bacteroidetes,1IFSM@117743|Flavobacteriia,2PBPD@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5325183_6	1237149.C900_00017	7.731e-41	162.0	COG0845@1|root,COG0845@2|Bacteria,4NF0X@976|Bacteroidetes,47P9V@768503|Cytophagia	976|Bacteroidetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
TLS3_k127_5337811_3	1202532.FF52_05280	1.519e-26	109.0	COG3501@1|root,COG3501@2|Bacteria,4NFPB@976|Bacteroidetes,1HZN7@117743|Flavobacteriia,2NU7J@237|Flavobacterium	976|Bacteroidetes	S	Rhs element Vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
TLS3_k127_5337811_2	1121859.KB890750_gene142	3.814e-50	179.0	COG4104@1|root,COG4104@2|Bacteria,4NSCZ@976|Bacteroidetes,47RUU@768503|Cytophagia	976|Bacteroidetes	S	PAAR motif	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
TLS3_k127_5337811_1	1443665.JACA01000013_gene4231	1.355e-52	188.0	COG3628@1|root,COG3628@2|Bacteria,4NSKN@976|Bacteroidetes,1I48Y@117743|Flavobacteriia,2YJZ4@290174|Aquimarina	976|Bacteroidetes	S	Gene 25-like lysozyme	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
TLS3_k127_5337811_0	1229487.AMYW01000027_gene2796	6.944e-88	306.0	COG3299@1|root,COG3299@2|Bacteria,4NF69@976|Bacteroidetes,1HYP7@117743|Flavobacteriia,2NT9S@237|Flavobacterium	976|Bacteroidetes	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
TLS3_k127_5339637_3	1408433.JHXV01000007_gene2927	2.524e-55	199.0	2AXDY@1|root,31PDA@2|Bacteria,4PJH6@976|Bacteroidetes,1IHII@117743|Flavobacteriia,2PB08@246874|Cryomorphaceae	976|Bacteroidetes	S	HmuY protein	-	-	-	-	-	-	-	-	-	-	-	-	HmuY
TLS3_k127_5339637_2	468059.AUHA01000002_gene811	1.01e-57	219.0	28MCN@1|root,2ZAQR@2|Bacteria,4NQ4Q@976|Bacteroidetes,1IT0J@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5339637_1	391587.KAOT1_01130	5.885e-185	651.0	COG2304@1|root,COG2911@1|root,COG2304@2|Bacteria,COG2911@2|Bacteria,4NH1J@976|Bacteroidetes,1I7SD@117743|Flavobacteriia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5339637_0	620914.JH621248_gene3138	1.303e-265	890.0	2DM7Q@1|root,322X9@2|Bacteria,4NKDH@976|Bacteroidetes,1HZT2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5344209_3	755732.Fluta_2095	1.667e-110	364.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,1HXXI@117743|Flavobacteriia,2PAR5@246874|Cryomorphaceae	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
TLS3_k127_5344209_2	755732.Fluta_2056	3.052e-144	472.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1HZBC@117743|Flavobacteriia,2PBD0@246874|Cryomorphaceae	976|Bacteroidetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
TLS3_k127_5344209_1	755732.Fluta_2055	1.388e-164	526.0	COG0438@1|root,COG0438@2|Bacteria,4PI5K@976|Bacteroidetes,1IGDT@117743|Flavobacteriia,2PB9M@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_5344209_4	755732.Fluta_2054	3.073e-71	251.0	COG1596@1|root,COG1596@2|Bacteria,4NPJB@976|Bacteroidetes,1ICQF@117743|Flavobacteriia,2PBRF@246874|Cryomorphaceae	976|Bacteroidetes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export
TLS3_k127_5344209_0	755732.Fluta_2053	5.174e-263	833.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia,2PA6D@246874|Cryomorphaceae	976|Bacteroidetes	DM	Chain length determinant protein	wzc	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
TLS3_k127_5346904_2	925409.KI911562_gene1739	3.774e-07	59.0	2EHJH@1|root,33BBD@2|Bacteria,4NXG2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5346904_0	1249997.JHZW01000002_gene192	2.773e-136	448.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,1HYB2@117743|Flavobacteriia,2PGGP@252356|Maribacter	976|Bacteroidetes	P	Citrate transporter	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
TLS3_k127_5346904_1	1250006.JHZZ01000001_gene3090	8.771e-86	295.0	COG0683@1|root,COG0683@2|Bacteria,4NIVQ@976|Bacteroidetes,1HZ6K@117743|Flavobacteriia	976|Bacteroidetes	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_53602_2	755732.Fluta_3647	7.622e-72	248.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,1HXSR@117743|Flavobacteriia,2PAMK@246874|Cryomorphaceae	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
TLS3_k127_53602_1	755732.Fluta_3646	1.446e-84	290.0	COG0791@1|root,COG0791@2|Bacteria,4NSZJ@976|Bacteroidetes,1I2VP@117743|Flavobacteriia,2PB7P@246874|Cryomorphaceae	976|Bacteroidetes	M	NlpC/P60 family	spr	-	-	ko:K13695	-	-	-	-	ko00000,ko01002	-	-	-	NLPC_P60
TLS3_k127_53602_0	1286632.P278_13440	0.0	1062.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,1HXRE@117743|Flavobacteriia	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
TLS3_k127_5369346_3	583355.Caka_1220	6.379e-51	196.0	COG0457@1|root,COG3379@1|root,COG3551@1|root,COG0457@2|Bacteria,COG3379@2|Bacteria,COG3551@2|Bacteria,46URB@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
TLS3_k127_5369346_5	1296416.JACB01000069_gene61	1.141e-08	66.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2YKFZ@290174|Aquimarina	976|Bacteroidetes	E	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
TLS3_k127_5369346_2	1223410.KN050846_gene1208	3.523e-77	274.0	COG3250@1|root,COG3250@2|Bacteria,4P3W0@976|Bacteroidetes,1I918@117743|Flavobacteriia	976|Bacteroidetes	G	Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
TLS3_k127_5369346_0	755732.Fluta_1738	0.0	1054.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1HYG5@117743|Flavobacteriia,2PAGZ@246874|Cryomorphaceae	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
TLS3_k127_5369346_1	755732.Fluta_1678	5.611e-104	343.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1HXT1@117743|Flavobacteriia,2PAQC@246874|Cryomorphaceae	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
TLS3_k127_5369346_4	1453500.AT05_01765	2.862e-27	119.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_8
TLS3_k127_5371003_2	755732.Fluta_0244	8.262e-08	57.0	COG2849@1|root,COG2849@2|Bacteria,4PC8C@976|Bacteroidetes,1IMSS@117743|Flavobacteriia,2PC0R@246874|Cryomorphaceae	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5371003_0	755732.Fluta_0243	2.904e-148	476.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1HWY7@117743|Flavobacteriia,2PA84@246874|Cryomorphaceae	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
TLS3_k127_5371003_1	755732.Fluta_0023	2.884e-87	307.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_537461_0	388413.ALPR1_14929	5.792e-146	471.0	COG3547@1|root,COG3547@2|Bacteria,4NIKY@976|Bacteroidetes	976|Bacteroidetes	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
TLS3_k127_5375862_2	1123277.KB893195_gene5571	8.613e-173	582.0	COG1361@1|root,COG3103@1|root,COG1361@2|Bacteria,COG3103@2|Bacteria,4NT9E@976|Bacteroidetes,47QTN@768503|Cytophagia	976|Bacteroidetes	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
TLS3_k127_5375862_5	755732.Fluta_2017	8.698e-57	203.0	28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,1I253@117743|Flavobacteriia,2PB3I@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5375862_1	1348583.ATLH01000016_gene3479	8.136e-198	652.0	COG0457@1|root,COG2304@1|root,COG4676@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,COG4676@2|Bacteria,4NGJS@976|Bacteroidetes,1I0CU@117743|Flavobacteriia,1F9VV@104264|Cellulophaga	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2135)	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,DUF2135,Plug,VIT
TLS3_k127_5375862_3	1121007.AUML01000008_gene1013	4.02e-152	497.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,1HY2R@117743|Flavobacteriia,2YGVF@290174|Aquimarina	976|Bacteroidetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
TLS3_k127_5375862_4	755732.Fluta_0354	5.039e-134	437.0	COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,1HWW0@117743|Flavobacteriia,2PA85@246874|Cryomorphaceae	976|Bacteroidetes	M	Sugar nucleotidyl transferase	glmU	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
TLS3_k127_5375862_0	755732.Fluta_0284	0.0	1206.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia,2PA9F@246874|Cryomorphaceae	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
TLS3_k127_5388306_7	755732.Fluta_0847	5.974e-23	98.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1HXCJ@117743|Flavobacteriia,2PABT@246874|Cryomorphaceae	976|Bacteroidetes	L	RQC	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
TLS3_k127_5388306_3	755732.Fluta_0818	1.653e-44	169.0	2ETBD@1|root,33KVB@2|Bacteria,4NSV4@976|Bacteroidetes,1ICSS@117743|Flavobacteriia,2PC0U@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
TLS3_k127_5388306_0	755732.Fluta_0819	1.424e-170	543.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1HX2N@117743|Flavobacteriia,2PAYE@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	3.5.1.32	ko:K01451	ko00360,map00360	-	R01424	RC00096,RC00162	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_5388306_4	1267211.KI669560_gene1519	1.818e-35	140.0	COG0730@1|root,COG0730@2|Bacteria,4NTZ8@976|Bacteroidetes	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_5388306_6	1268072.PSAB_04075	8.507e-30	124.0	COG5646@1|root,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,4HINV@91061|Bacilli,26YRN@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_5388306_2	755732.Fluta_0820	3.687e-101	341.0	COG0318@1|root,COG0318@2|Bacteria,4NDXK@976|Bacteroidetes,1IJB2@117743|Flavobacteriia,2PA5N@246874|Cryomorphaceae	976|Bacteroidetes	IQ	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
TLS3_k127_5388306_1	1453500.AT05_08920	6.666e-129	419.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1HY0T@117743|Flavobacteriia	976|Bacteroidetes	F	nucleoside transporter	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
TLS3_k127_5412415_10	55529.EKX54485	0.0001293	53.0	COG0457@1|root,KOG0548@2759|Eukaryota	2759|Eukaryota	J	positive regulation of catalytic activity in other organism involved in symbiotic interaction	TTC28	GO:0000922,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005813,GO:0005815,GO:0005819,GO:0005856,GO:0007346,GO:0008150,GO:0015630,GO:0019899,GO:0019900,GO:0030496,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044430,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051233,GO:0051726,GO:0065007,GO:0072686,GO:0097431,GO:1990023	-	ko:K14861	-	-	-	-	ko00000,ko03009	-	-	-	CHAT,TPR_12,TPR_16,TPR_7,TPR_8
TLS3_k127_5412415_5	746697.Aeqsu_3202	3.625e-54	201.0	COG0526@1|root,COG0526@2|Bacteria,4NZHV@976|Bacteroidetes,1IAZB@117743|Flavobacteriia	976|Bacteroidetes	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TLS3_k127_5412415_3	565034.BHWA1_02277	7.107e-97	334.0	COG1757@1|root,COG1757@2|Bacteria,2J72N@203691|Spirochaetes	203691|Spirochaetes	C	Na+/H+ antiporter family	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
TLS3_k127_5412415_8	313603.FB2170_13086	1.66e-37	147.0	COG0431@1|root,COG0431@2|Bacteria,4NNMA@976|Bacteroidetes,1I244@117743|Flavobacteriia,2PHHW@252356|Maribacter	976|Bacteroidetes	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
TLS3_k127_5412415_4	1122179.KB890413_gene4895	3.086e-54	194.0	COG2350@1|root,COG2350@2|Bacteria,4NNMS@976|Bacteroidetes,1ITUD@117747|Sphingobacteriia	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
TLS3_k127_5412415_1	755732.Fluta_3488	1.989e-117	384.0	COG0115@1|root,COG0115@2|Bacteria,4NG0G@976|Bacteroidetes,1HYPS@117743|Flavobacteriia,2PAUN@246874|Cryomorphaceae	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_5412415_6	755732.Fluta_3489	1.493e-46	175.0	COG0705@1|root,COG0705@2|Bacteria,4NECA@976|Bacteroidetes,1HYWY@117743|Flavobacteriia,2PB2Z@246874|Cryomorphaceae	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TLS3_k127_5412415_0	755732.Fluta_3490	4.943e-123	413.0	COG2989@1|root,COG2989@2|Bacteria,4NH3J@976|Bacteroidetes,1I08J@117743|Flavobacteriia,2PBIE@246874|Cryomorphaceae	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
TLS3_k127_5412415_2	755732.Fluta_3491	4.605e-101	332.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,1HX41@117743|Flavobacteriia,2PA6Y@246874|Cryomorphaceae	976|Bacteroidetes	G	Ribulose-phosphate 3 epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
TLS3_k127_5412415_9	1094466.KQS_10395	1.389e-18	92.0	COG2318@1|root,COG2318@2|Bacteria,4NSE5@976|Bacteroidetes,1I4NU@117743|Flavobacteriia,2NWYZ@237|Flavobacterium	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
TLS3_k127_5412415_7	755732.Fluta_3570	5.959e-38	148.0	28P29@1|root,2ZBYD@2|Bacteria,4NMK6@976|Bacteroidetes,1I98E@117743|Flavobacteriia,2PB6I@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_541748_1	491205.JARQ01000005_gene1663	4.092e-250	776.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,4NE85@976|Bacteroidetes,1HY7H@117743|Flavobacteriia,3ZP7F@59732|Chryseobacterium	976|Bacteroidetes	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumB	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
TLS3_k127_541748_0	926562.Oweho_1116	0.0	1139.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,1HWMX@117743|Flavobacteriia	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
TLS3_k127_541748_2	1313421.JHBV01000030_gene2310	5.015e-126	409.0	COG3752@1|root,COG3752@2|Bacteria,4NJXA@976|Bacteroidetes	976|Bacteroidetes	S	COGs COG3752 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
TLS3_k127_541748_3	755732.Fluta_1125	3.735e-116	377.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,1I14P@117743|Flavobacteriia,2PBAQ@246874|Cryomorphaceae	976|Bacteroidetes	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
TLS3_k127_5425209_0	992406.RIA_1764	1.223e-65	243.0	COG3975@1|root,COG3975@2|Bacteria,4NI7I@976|Bacteroidetes,1HYPY@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
TLS3_k127_5429366_0	755732.Fluta_2481	3.209e-105	364.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia,2PA9P@246874|Cryomorphaceae	976|Bacteroidetes	L	UvrD/REP helicase N-terminal domain	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
TLS3_k127_5429366_1	1267211.KI669560_gene694	1.78e-28	133.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1IPPI@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
TLS3_k127_5434924_13	926556.Echvi_3583	0.0004888	47.0	COG3210@1|root,COG3210@2|Bacteria,4PP9Z@976|Bacteroidetes,47YJV@768503|Cytophagia	976|Bacteroidetes	U	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
TLS3_k127_5434924_12	1121012.AUKX01000042_gene2493	2.092e-06	49.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,4NHA0@976|Bacteroidetes,1HZ9E@117743|Flavobacteriia,23GZI@178469|Arenibacter	976|Bacteroidetes	H	MoaC family	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
TLS3_k127_5434924_2	398720.MED217_08730	3.835e-114	377.0	COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,1HWK6@117743|Flavobacteriia,2XIHR@283735|Leeuwenhoekiella	976|Bacteroidetes	H	Molybdenum Cofactor Synthesis C	moaA	-	4.1.99.22,4.6.1.17	ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
TLS3_k127_5434924_6	745718.JADT01000023_gene1451	2.063e-52	194.0	COG0791@1|root,COG0791@2|Bacteria,4NSRM@976|Bacteroidetes,1I9IJ@117743|Flavobacteriia	976|Bacteroidetes	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5434924_11	47716.JOFH01000027_gene2964	8.929e-10	70.0	COG3325@1|root,COG3325@2|Bacteria,2GNWP@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 18 family	-	-	3.2.1.96	ko:K01227	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_18
TLS3_k127_5434924_3	1408433.JHXV01000027_gene3711	3.474e-96	325.0	COG2234@1|root,COG2234@2|Bacteria,4NIQX@976|Bacteroidetes,1I0UI@117743|Flavobacteriia,2PBCK@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
TLS3_k127_5434924_5	1124780.ANNU01000025_gene3368	6.464e-58	205.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,47QER@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
TLS3_k127_5434924_1	1408433.JHXV01000006_gene2765	5.059e-123	409.0	COG2272@1|root,COG2272@2|Bacteria,4PI06@976|Bacteroidetes,1IG13@117743|Flavobacteriia,2PB7F@246874|Cryomorphaceae	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	COesterase
TLS3_k127_5434924_4	760192.Halhy_5351	4.361e-74	271.0	COG1807@1|root,COG1807@2|Bacteria,4NPS7@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5434924_7	28737.XP_006897144.1	5.219e-52	194.0	COG1262@1|root,2QVDG@2759|Eukaryota,38C17@33154|Opisthokonta,3B9T4@33208|Metazoa,3CX3Y@33213|Bilateria,4819N@7711|Chordata,48WT5@7742|Vertebrata,3JC51@40674|Mammalia,354DU@311790|Afrotheria	33208|Metazoa	S	factor 1	SUMF1	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0006464,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0012505,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0031974,GO:0036211,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0070013,GO:0071704,GO:0120147,GO:1901135,GO:1901564,GO:1903135,GO:1903509	1.8.3.7	ko:K13444	ko04142,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase
TLS3_k127_5434924_0	1313421.JHBV01000019_gene5332	2.74e-151	494.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,1IVH8@117747|Sphingobacteriia	976|Bacteroidetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TLS3_k127_5434924_10	866536.Belba_2302	3.254e-33	136.0	2CE7Q@1|root,32RZA@2|Bacteria,4NSYK@976|Bacteroidetes,47R4R@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5434924_8	1229487.AMYW01000027_gene2785	6.736e-43	181.0	COG3210@1|root,COG3210@2|Bacteria,4PP9Z@976|Bacteroidetes	976|Bacteroidetes	U	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
TLS3_k127_5443132_1	755732.Fluta_1367	9.081e-181	575.0	COG4935@1|root,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,1HYKE@117743|Flavobacteriia,2PBFE@246874|Cryomorphaceae	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
TLS3_k127_5443132_0	755732.Fluta_1333	2.262e-191	607.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,1HYME@117743|Flavobacteriia,2PA8N@246874|Cryomorphaceae	976|Bacteroidetes	Q	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_5451294_5	926549.KI421517_gene3311	2.045e-48	194.0	COG1520@1|root,COG3210@1|root,COG3405@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3405@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
TLS3_k127_5451294_8	1223410.KN050846_gene1094	0.0003856	53.0	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	MAM,Sortilin-Vps10
TLS3_k127_5451294_2	1392498.JQLH01000001_gene1343	6.646e-88	294.0	COG4339@1|root,COG4339@2|Bacteria,4NP5E@976|Bacteroidetes,1I2GP@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5451294_3	761193.Runsl_4459	7.5e-67	229.0	2DK0G@1|root,30823@2|Bacteria,4NNIV@976|Bacteroidetes,47PPM@768503|Cytophagia	976|Bacteroidetes	S	Rifampin ADP-ribosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Arr-ms
TLS3_k127_5451294_0	760192.Halhy_0083	5.508e-140	467.0	COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes,1IQ9M@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
TLS3_k127_5451294_6	1189612.A33Q_1608	3.365e-41	156.0	2C945@1|root,32W5M@2|Bacteria	2|Bacteria	-	-	-	-	5.4.4.1	ko:K01865	ko00627,ko01120,map00627,map01120	-	-	-	ko00000,ko00001,ko01000	-	-	-	-
TLS3_k127_5451294_7	1189620.AJXL01000008_gene2278	1.552e-31	125.0	2E3D8@1|root,32YCF@2|Bacteria,4NUPM@976|Bacteroidetes,1I544@117743|Flavobacteriia,2NX84@237|Flavobacterium	976|Bacteroidetes	S	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_2
TLS3_k127_5451294_1	1137281.D778_02218	1.817e-138	445.0	COG0484@1|root,COG0484@2|Bacteria,4NE4X@976|Bacteroidetes,1HXJ8@117743|Flavobacteriia	976|Bacteroidetes	O	molecular chaperone	dnaJ2	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
TLS3_k127_5451294_4	1380384.JADN01000008_gene1251	7.126e-60	210.0	COG3457@1|root,COG3457@2|Bacteria,4NFEJ@976|Bacteroidetes,1HYZY@117743|Flavobacteriia	976|Bacteroidetes	E	amino acid racemase	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
TLS3_k127_5465664_1	983544.Lacal_1902	6.562e-99	324.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1HXE2@117743|Flavobacteriia	976|Bacteroidetes	C	Thioredoxin reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_5465664_2	1408433.JHXV01000005_gene2340	1.514e-89	299.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,1HXFE@117743|Flavobacteriia,2PAS7@246874|Cryomorphaceae	976|Bacteroidetes	O	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
TLS3_k127_5465664_0	755732.Fluta_3446	4.575e-302	933.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HY0V@117743|Flavobacteriia,2PAHK@246874|Cryomorphaceae	976|Bacteroidetes	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	accD5	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
TLS3_k127_5465664_3	755732.Fluta_3445	6.917e-63	220.0	COG2153@1|root,COG2153@2|Bacteria,4NQPR@976|Bacteroidetes,1I23R@117743|Flavobacteriia,2PB3E@246874|Cryomorphaceae	976|Bacteroidetes	S	Acetyltransferase (GNAT) domain	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
TLS3_k127_5465664_4	755732.Fluta_3444	5.994e-19	89.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,1HX3E@117743|Flavobacteriia,2PBJM@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Peptidase family M13	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
TLS3_k127_5484606_0	1296415.JACC01000030_gene2776	8.098e-253	802.0	COG3209@1|root,COG3209@2|Bacteria,4NF0G@976|Bacteroidetes,1I0VK@117743|Flavobacteriia	976|Bacteroidetes	M	RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midN
TLS3_k127_5494140_0	1408433.JHXV01000024_gene1458	1.395e-199	641.0	COG1629@1|root,COG1629@2|Bacteria,4PP5X@976|Bacteroidetes	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3
TLS3_k127_550702_1	755732.Fluta_3272	1.084e-93	312.0	COG4099@1|root,COG4099@2|Bacteria,4NFSH@976|Bacteroidetes,1HY30@117743|Flavobacteriia	976|Bacteroidetes	E	Phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Esterase,Peptidase_S9
TLS3_k127_550702_2	313598.MED152_13344	1.891e-06	55.0	COG2010@1|root,COG2010@2|Bacteria,4NWPQ@976|Bacteroidetes,1IN2Q@117743|Flavobacteriia,3VWUB@52959|Polaribacter	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_550702_0	1408433.JHXV01000001_gene768	2.292e-237	753.0	COG1404@1|root,COG1404@2|Bacteria,4NTWX@976|Bacteroidetes	976|Bacteroidetes	O	Peptidase, S8 S53 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_5524112_4	1550091.JROE01000001_gene3994	3.979e-05	53.0	2EB9D@1|root,3359V@2|Bacteria,4PGT8@976|Bacteroidetes,1IU9W@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5524112_3	1268240.ATFI01000001_gene3319	2.107e-05	57.0	2C4JY@1|root,33363@2|Bacteria,4NUXB@976|Bacteroidetes,2FV2J@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5524112_0	755732.Fluta_3899	4.643e-170	538.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1HX04@117743|Flavobacteriia,2PA4I@246874|Cryomorphaceae	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
TLS3_k127_5524112_1	655815.ZPR_2020	1.302e-22	105.0	COG0545@1|root,COG0545@2|Bacteria,4NQJS@976|Bacteroidetes,1I376@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
TLS3_k127_5524112_2	1233950.IW22_12920	1.628e-11	65.0	COG3735@1|root,COG3735@2|Bacteria,4NPI6@976|Bacteroidetes,1I2GB@117743|Flavobacteriia,3ZP6P@59732|Chryseobacterium	976|Bacteroidetes	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
TLS3_k127_5527191_3	755732.Fluta_0185	0.0001485	45.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,1I1EE@117743|Flavobacteriia,2PB5I@246874|Cryomorphaceae	976|Bacteroidetes	S	gliding motility protein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5527191_0	755732.Fluta_0184	1.152e-151	491.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1HXF3@117743|Flavobacteriia,2PABH@246874|Cryomorphaceae	976|Bacteroidetes	S	Transporter associated domain	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
TLS3_k127_5527191_1	755732.Fluta_0183	3.91e-57	203.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I27K@117743|Flavobacteriia,2PB1R@246874|Cryomorphaceae	976|Bacteroidetes	L	TIGRFAM single stranded DNA-binding protein (ssb)	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
TLS3_k127_5527191_2	929562.Emtol_2241	1.032e-05	50.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,47KTH@768503|Cytophagia	976|Bacteroidetes	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
TLS3_k127_5535763_8	641526.ADIWIN_2570	4.194e-05	54.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Reprolysin_3,Reprolysin_4,Reprolysin_5
TLS3_k127_5535763_3	391587.KAOT1_03737	1.226e-71	258.0	2C8K2@1|root,33RA7@2|Bacteria,4P1C9@976|Bacteroidetes,1I77M@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5535763_7	319225.Plut_1185	2.327e-07	52.0	COG3876@1|root,COG3876@2|Bacteria,1FDF0@1090|Chlorobi	1090|Chlorobi	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
TLS3_k127_5535763_0	755732.Fluta_0800	7.715e-191	629.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,1HX7Z@117743|Flavobacteriia,2PAQ0@246874|Cryomorphaceae	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
TLS3_k127_5535763_5	485917.Phep_2585	1.556e-19	98.0	28NAE@1|root,2ZBE7@2|Bacteria,4NJNX@976|Bacteroidetes,1IS37@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (Porph_ging)	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
TLS3_k127_5535763_6	1121870.AUAA01000001_gene2684	1.2e-08	60.0	2E82Z@1|root,332GZ@2|Bacteria,4NVRZ@976|Bacteroidetes,1I5FX@117743|Flavobacteriia,3HIDP@358033|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5535763_2	755732.Fluta_0875	2.607e-90	301.0	COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,1HWKF@117743|Flavobacteriia,2PAXI@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Scaffold protein Nfu NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
TLS3_k127_5535763_1	755732.Fluta_0871	8.392e-125	410.0	COG1629@1|root,COG4771@2|Bacteria,4NE7A@976|Bacteroidetes,1IIH0@117743|Flavobacteriia,2PA5Q@246874|Cryomorphaceae	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,HMA,Plug,TonB_dep_Rec
TLS3_k127_553697_2	755732.Fluta_1397	4.389e-50	188.0	2AKYC@1|root,31BRY@2|Bacteria,4NQYZ@976|Bacteroidetes,1I37P@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_553697_1	755732.Fluta_1229	9.018e-80	269.0	COG0251@1|root,COG0251@2|Bacteria,4NMHF@976|Bacteroidetes,1I1II@117743|Flavobacteriia,2PARM@246874|Cryomorphaceae	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	3.5.99.5	ko:K15067	ko00380,map00380	-	R03887	RC01015	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
TLS3_k127_5538641_0	388467.A19Y_3668	7.479e-212	670.0	COG0286@1|root,COG0286@2|Bacteria,1G119@1117|Cyanobacteria,1H81R@1150|Oscillatoriales	1117|Cyanobacteria	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
TLS3_k127_5538641_1	1226322.HMPREF1545_02190	1.081e-12	72.0	2F2Z4@1|root,33VUG@2|Bacteria,1VVGK@1239|Firmicutes,251AI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5538641_2	290402.Cbei_2045	2.438e-09	68.0	COG1787@1|root,COG1787@2|Bacteria,1UJ9F@1239|Firmicutes,25EYR@186801|Clostridia,36KI2@31979|Clostridiaceae	186801|Clostridia	L	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5559739_8	1122164.JHWF01000007_gene1078	4.582e-43	162.0	COG0769@1|root,COG1181@1|root,COG0769@2|Bacteria,COG1181@2|Bacteria,1NRVH@1224|Proteobacteria,1T4M0@1236|Gammaproteobacteria,1JDM3@118969|Legionellales	118969|Legionellales	F	Mur ligase family, glutamate ligase domain	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,RimK
TLS3_k127_5559739_2	658187.LDG_5141	1.893e-96	323.0	COG4242@1|root,COG4242@2|Bacteria,1PR9J@1224|Proteobacteria,1S6GB@1236|Gammaproteobacteria,1JD09@118969|Legionellales	118969|Legionellales	PQ	Peptidase family S51	-	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
TLS3_k127_5559739_4	1341181.FLJC2902T_22360	8.65e-74	249.0	COG2764@1|root,COG2764@2|Bacteria,4NQD7@976|Bacteroidetes,1I2C0@117743|Flavobacteriia,2NW2Z@237|Flavobacterium	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
TLS3_k127_5559739_7	760192.Halhy_0143	5.218e-50	181.0	COG2764@1|root,COG2764@2|Bacteria,4NSNJ@976|Bacteroidetes,1ITJD@117747|Sphingobacteriia	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
TLS3_k127_5559739_5	1492737.FEM08_16210	9.405e-72	243.0	COG3865@1|root,COG3865@2|Bacteria,4NE70@976|Bacteroidetes,1HZR2@117743|Flavobacteriia,2NX99@237|Flavobacterium	976|Bacteroidetes	H	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
TLS3_k127_5559739_6	1107311.Q767_02210	5.003e-56	201.0	COG2764@1|root,COG2764@2|Bacteria,4NQD7@976|Bacteroidetes,1I2AQ@117743|Flavobacteriia,2NW94@237|Flavobacterium	976|Bacteroidetes	S	Glyoxalase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
TLS3_k127_5559739_3	1121887.AUDK01000023_gene3424	5.424e-79	266.0	COG3832@1|root,COG3832@2|Bacteria,4NPE8@976|Bacteroidetes,1I8XE@117743|Flavobacteriia,2NW7M@237|Flavobacterium	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_5559739_0	1229487.AMYW01000018_gene4160	4.186e-165	527.0	COG4977@1|root,COG4977@2|Bacteria,4NGSR@976|Bacteroidetes,1HZKB@117743|Flavobacteriia,2NUZP@237|Flavobacterium	976|Bacteroidetes	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
TLS3_k127_5559739_10	1121899.Q764_04805	7.035e-09	57.0	COG3548@1|root,COG3548@2|Bacteria,4NPIF@976|Bacteroidetes,1I1Y3@117743|Flavobacteriia,2NU69@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
TLS3_k127_5559739_11	1189619.pgond44_08250	7.388e-07	62.0	COG2133@1|root,COG3210@1|root,COG2133@2|Bacteria,COG3210@2|Bacteria,4NIDX@976|Bacteroidetes,1I0AY@117743|Flavobacteriia	976|Bacteroidetes	U	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_5559739_1	1484460.JSWG01000015_gene1033	3.671e-147	487.0	COG1345@1|root,COG1361@1|root,COG1520@1|root,COG2866@1|root,COG3291@1|root,COG3391@1|root,COG4733@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG1520@2|Bacteria,COG2866@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia	976|Bacteroidetes	DZ	adhesin AidA-related	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gal_Lectin,HYR,Laminin_G_3,SprB,TSP_3
TLS3_k127_5559739_9	755732.Fluta_3356	4.795e-12	79.0	COG3210@1|root,COG3210@2|Bacteria,4NGEX@976|Bacteroidetes,1HZV9@117743|Flavobacteriia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5566354_0	592029.DDD_3107	6.943e-107	348.0	COG3751@1|root,COG3751@2|Bacteria,4NZTB@976|Bacteroidetes,1I8H6@117743|Flavobacteriia	976|Bacteroidetes	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	-	ko:K07336	-	-	-	-	ko00000,ko01000	-	-	-	2OG-FeII_Oxy_3
TLS3_k127_5566354_4	864565.HMPREF0379_0322	0.0001884	53.0	COG0860@1|root,COG0860@2|Bacteria,1UN2C@1239|Firmicutes,25GV5@186801|Clostridia	186801|Clostridia	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Cu_amine_oxidN1
TLS3_k127_5566354_2	1296415.JACC01000039_gene4039	3.559e-40	163.0	2EB3B@1|root,33543@2|Bacteria,4NXCQ@976|Bacteroidetes,1I4V4@117743|Flavobacteriia,2YJ30@290174|Aquimarina	976|Bacteroidetes	S	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
TLS3_k127_5566354_3	1123234.AUKI01000020_gene902	5.491e-15	79.0	2E32S@1|root,32Y2Z@2|Bacteria,4NW5U@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5566354_1	402612.FP0617	4.948e-44	180.0	COG2885@1|root,COG5295@1|root,COG2885@2|Bacteria,COG5295@2|Bacteria,4NN21@976|Bacteroidetes,1I1UJ@117743|Flavobacteriia,2NUBX@237|Flavobacterium	976|Bacteroidetes	UW	arginyl-trna synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_559778_0	755732.Fluta_0946	1.189e-128	413.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HXA1@117743|Flavobacteriia,2PA5W@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TLS3_k127_559778_1	1356852.N008_09835	2.065e-13	76.0	COG2374@1|root,COG4447@1|root,COG2374@2|Bacteria,COG4447@2|Bacteria,4PPNQ@976|Bacteroidetes,47YQD@768503|Cytophagia	976|Bacteroidetes	G	pectinesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5598099_3	755732.Fluta_0895	1.063e-58	204.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1HX0U@117743|Flavobacteriia,2PAC8@246874|Cryomorphaceae	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
TLS3_k127_5598099_5	643867.Ftrac_2948	1.488e-41	157.0	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,47R4H@768503|Cytophagia	976|Bacteroidetes	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
TLS3_k127_5598099_2	755732.Fluta_2199	5.039e-82	284.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1HX0P@117743|Flavobacteriia,2PAN2@246874|Cryomorphaceae	976|Bacteroidetes	M	NAD(P)H-binding	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
TLS3_k127_5598099_0	755732.Fluta_1984	2.055e-219	699.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1HWWU@117743|Flavobacteriia,2PAM1@246874|Cryomorphaceae	976|Bacteroidetes	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_127,Glyco_hydro_76,Thioredox_DsbH
TLS3_k127_5598099_1	755732.Fluta_1983	2.706e-91	312.0	COG2755@1|root,COG2755@2|Bacteria,4NHT6@976|Bacteroidetes,1HYAV@117743|Flavobacteriia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
TLS3_k127_5600310_1	1238450.VIBNISOn1_1070053	5.255e-23	115.0	COG1752@1|root,COG1752@2|Bacteria,1PWKF@1224|Proteobacteria,1TIQ9@1236|Gammaproteobacteria,1XZG6@135623|Vibrionales	135623|Vibrionales	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
TLS3_k127_5600310_0	1144313.PMI10_01645	1.037e-175	558.0	COG0464@1|root,COG0464@2|Bacteria,4NFWG@976|Bacteroidetes,1HZA4@117743|Flavobacteriia,2NV04@237|Flavobacterium	976|Bacteroidetes	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
TLS3_k127_5606164_0	1168289.AJKI01000003_gene2887	1.104e-205	676.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,2FWCM@200643|Bacteroidia,3XKSI@558415|Marinilabiliaceae	976|Bacteroidetes	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS3_k127_5606164_1	309799.DICTH_0575	0.0002582	46.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS3_k127_5607603_2	1123371.ATXH01000011_gene100	3.558e-17	94.0	COG0457@1|root,COG0457@2|Bacteria,2GI85@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5607603_0	755732.Fluta_3103	2.629e-68	235.0	COG0566@1|root,COG0566@2|Bacteria,4NMEA@976|Bacteroidetes,1I19V@117743|Flavobacteriia,2PBT1@246874|Cryomorphaceae	976|Bacteroidetes	J	SpoU rRNA Methylase family	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
TLS3_k127_5607603_1	1202532.FF52_03165	3.365e-48	182.0	COG1715@1|root,COG1715@2|Bacteria,4PCT8@976|Bacteroidetes,1IDBA@117743|Flavobacteriia,2NXXZ@237|Flavobacterium	976|Bacteroidetes	V	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5610551_0	1123037.AUDE01000005_gene3023	4.791e-100	331.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1HWMZ@117743|Flavobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
TLS3_k127_5610551_3	521011.Mpal_1810	2.929e-28	133.0	COG3291@1|root,arCOG02554@1|root,arCOG02559@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02554@2157|Archaea,arCOG02559@2157|Archaea,2Y7Y8@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
TLS3_k127_5610551_1	1286632.P278_00840	7.292e-78	262.0	COG1764@1|root,COG1764@2|Bacteria,4NNF7@976|Bacteroidetes,1I1XV@117743|Flavobacteriia	976|Bacteroidetes	O	Peroxiredoxin	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
TLS3_k127_5610551_2	574376.BAMA_05930	2.415e-60	223.0	COG1680@1|root,COG1680@2|Bacteria,1UZZ5@1239|Firmicutes,4HA1I@91061|Bacilli,1ZBMQ@1386|Bacillus	91061|Bacilli	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
TLS3_k127_5615951_1	1237149.C900_00764	3.35e-157	505.0	COG0761@1|root,COG0761@2|Bacteria,4NDUX@976|Bacteroidetes,47M0Y@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
TLS3_k127_5615951_0	755732.Fluta_3946	4.134e-199	634.0	COG1418@1|root,COG2114@1|root,COG2199@1|root,COG1418@2|Bacteria,COG2114@2|Bacteria,COG3706@2|Bacteria,4PI9X@976|Bacteroidetes,1IG3V@117743|Flavobacteriia,2PBI5@246874|Cryomorphaceae	976|Bacteroidetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
TLS3_k127_5615951_2	1408433.JHXV01000042_gene1425	5.073e-73	250.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,1HX1J@117743|Flavobacteriia,2PATS@246874|Cryomorphaceae	976|Bacteroidetes	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
TLS3_k127_5615951_3	755732.Fluta_0133	1.222e-38	144.0	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,1I42P@117743|Flavobacteriia,2PB54@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
TLS3_k127_5662049_0	1249997.JHZW01000003_gene2531	8.994e-103	350.0	COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,1HX3U@117743|Flavobacteriia	976|Bacteroidetes	P	COG0471 Di- and tricarboxylate	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
TLS3_k127_5662049_1	45351.EDO26621	1.988e-73	256.0	COG3022@1|root,2QWDD@2759|Eukaryota,3A0UI@33154|Opisthokonta,3BPUS@33208|Metazoa	33208|Metazoa	S	Peroxide stress protein YaaA	-	-	-	-	-	-	-	-	-	-	-	-	H2O2_YaaD
TLS3_k127_5662049_2	1168289.AJKI01000014_gene2052	2.238e-45	172.0	COG1670@1|root,COG1670@2|Bacteria,4NQB5@976|Bacteroidetes,2FTXH@200643|Bacteroidia,3XKUU@558415|Marinilabiliaceae	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TLS3_k127_5662049_4	880071.Fleli_3340	0.0003338	46.0	COG0729@1|root,COG0729@2|Bacteria,4NVBC@976|Bacteroidetes,47Y1F@768503|Cytophagia	976|Bacteroidetes	M	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
TLS3_k127_566518_18	1313421.JHBV01000042_gene3228	3.402e-22	96.0	COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,1IT6S@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
TLS3_k127_566518_13	471854.Dfer_2034	3.237e-47	177.0	arCOG05416@1|root,2ZZTD@2|Bacteria,4NNMY@976|Bacteroidetes,47Q57@768503|Cytophagia	976|Bacteroidetes	S	lycopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_566518_10	1408433.JHXV01000001_gene931	6.207e-69	237.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,1I19W@117743|Flavobacteriia,2PAVP@246874|Cryomorphaceae	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
TLS3_k127_566518_5	1408433.JHXV01000001_gene932	2.526e-94	320.0	COG2831@1|root,COG2831@2|Bacteria,4PKNE@976|Bacteroidetes,1IKE1@117743|Flavobacteriia,2PAR6@246874|Cryomorphaceae	976|Bacteroidetes	U	hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_566518_15	1517682.HW49_05310	5.381e-30	131.0	2D45Q@1|root,32TGB@2|Bacteria,4NTFZ@976|Bacteroidetes,2FU27@200643|Bacteroidia,230P4@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_566518_9	1121899.Q764_04435	1.255e-74	257.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,1HXBA@117743|Flavobacteriia,2NS6J@237|Flavobacterium	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
TLS3_k127_566518_7	755732.Fluta_2756	1.362e-87	294.0	COG0527@1|root,COG0527@2|Bacteria,4NJDY@976|Bacteroidetes,1HYZX@117743|Flavobacteriia,2PBM1@246874|Cryomorphaceae	976|Bacteroidetes	E	aspartate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_566518_17	1408433.JHXV01000002_gene300	2.438e-22	97.0	2E5GR@1|root,3308C@2|Bacteria,4NUPC@976|Bacteroidetes,1I51R@117743|Flavobacteriia,2PC1K@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_566518_12	755732.Fluta_2755	1.038e-54	200.0	2A95Z@1|root,30YAJ@2|Bacteria,4PC29@976|Bacteroidetes,1ICRZ@117743|Flavobacteriia,2PBY8@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_566518_6	755732.Fluta_2754	2.785e-92	314.0	28I9R@1|root,2Z8CE@2|Bacteria,4NE54@976|Bacteroidetes,1HWWD@117743|Flavobacteriia,2PB5T@246874|Cryomorphaceae	976|Bacteroidetes	S	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
TLS3_k127_566518_4	755732.Fluta_2753	7.057e-110	360.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,1HWKT@117743|Flavobacteriia,2PAC4@246874|Cryomorphaceae	976|Bacteroidetes	S	MazG nucleotide pyrophosphohydrolase domain	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
TLS3_k127_566518_0	755732.Fluta_2752	1.64e-317	990.0	COG1629@1|root,COG1629@2|Bacteria,4NKDS@976|Bacteroidetes,1IKE0@117743|Flavobacteriia,2PADW@246874|Cryomorphaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
TLS3_k127_566518_11	1380384.JADN01000007_gene1378	9.297e-62	215.0	COG1959@1|root,COG1959@2|Bacteria,4NNN2@976|Bacteroidetes,1I1Z9@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	cymR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
TLS3_k127_566518_16	391587.KAOT1_12817	2.319e-27	113.0	COG3205@1|root,COG3205@2|Bacteria,4NV6E@976|Bacteroidetes,1I4TA@117743|Flavobacteriia	976|Bacteroidetes	S	Predicted membrane protein (DUF2061)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2061
TLS3_k127_566518_8	1286632.P278_01940	1.023e-84	285.0	COG0175@1|root,COG0175@2|Bacteria,4PH3N@976|Bacteroidetes,1HWTX@117743|Flavobacteriia	976|Bacteroidetes	EH	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
TLS3_k127_566518_2	1121895.Q765_07040	1.906e-150	479.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,1HXPZ@117743|Flavobacteriia,2NSGA@237|Flavobacterium	976|Bacteroidetes	EH	Sulfate adenylyltransferase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
TLS3_k127_566518_1	1286632.P278_01960	2.658e-155	501.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,1HXRK@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
TLS3_k127_566518_14	1304874.JAFY01000002_gene1055	1.415e-44	168.0	COG1704@1|root,COG1704@2|Bacteria,3TAYK@508458|Synergistetes	508458|Synergistetes	S	PFAM LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
TLS3_k127_566518_3	755732.Fluta_1527	1.25e-130	436.0	COG4907@1|root,COG4907@2|Bacteria,4NJKC@976|Bacteroidetes,1I111@117743|Flavobacteriia	976|Bacteroidetes	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
TLS3_k127_566518_19	1408433.JHXV01000010_gene544	1.645e-07	59.0	COG1835@1|root,COG1835@2|Bacteria,4NSAJ@976|Bacteroidetes,1IG0S@117743|Flavobacteriia,2PBT0@246874|Cryomorphaceae	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS3_k127_5674952_2	526222.Desal_2733	1.329e-16	87.0	2AJB7@1|root,319WD@2|Bacteria,1R527@1224|Proteobacteria,43BE6@68525|delta/epsilon subdivisions,2X6SN@28221|Deltaproteobacteria,2MH6B@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	FRG	-	-	-	-	-	-	-	-	-	-	-	-	FRG
TLS3_k127_5674952_0	33876.JNXY01000006_gene976	6.888e-33	138.0	2F20F@1|root,33UZM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5674952_3	426114.THI_1452	7.377e-09	62.0	29GEV@1|root,303CN@2|Bacteria,1MXRD@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5677436_5	755732.Fluta_0608	4.676e-79	266.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,1HXWT@117743|Flavobacteriia,2PAAG@246874|Cryomorphaceae	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
TLS3_k127_5677436_4	880070.Cycma_2374	1.882e-81	278.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,47JG4@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
TLS3_k127_5677436_0	755732.Fluta_0606	1.229e-234	747.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,1I54C@117743|Flavobacteriia,2PAIC@246874|Cryomorphaceae	976|Bacteroidetes	Q	PFAM FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS3_k127_5677436_1	755732.Fluta_0605	3.259e-100	342.0	COG3291@1|root,COG3291@2|Bacteria,4NM0P@976|Bacteroidetes,1I0CF@117743|Flavobacteriia,2PAUX@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M14
TLS3_k127_5677436_6	313603.FB2170_00265	3.414e-60	214.0	COG0778@1|root,COG0778@2|Bacteria,4NF4K@976|Bacteroidetes,1I1DI@117743|Flavobacteriia,2PHHI@252356|Maribacter	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
TLS3_k127_5677436_3	1121896.JMLU01000001_gene1018	2.003e-92	309.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,1HYY2@117743|Flavobacteriia,2NSN5@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
TLS3_k127_5677436_2	1408433.JHXV01000005_gene2360	1.872e-93	318.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1HY2Q@117743|Flavobacteriia,2PBZ4@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6
TLS3_k127_5678473_3	755732.Fluta_1682	7.602e-86	322.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4PI0A@976|Bacteroidetes,1IMVQ@117743|Flavobacteriia,2PBY2@246874|Cryomorphaceae	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_5678473_2	1227739.Hsw_3425	4.809e-87	300.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,47JWQ@768503|Cytophagia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
TLS3_k127_5678473_0	1227739.Hsw_3426	2.645e-231	736.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
TLS3_k127_5678473_1	755732.Fluta_3347	3.358e-141	456.0	COG1533@1|root,COG1533@2|Bacteria,4NE62@976|Bacteroidetes,1HYJS@117743|Flavobacteriia,2PBEU@246874|Cryomorphaceae	976|Bacteroidetes	L	PFAM Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TLS3_k127_5678473_4	755732.Fluta_1482	7.574e-49	184.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_5678473_5	655815.ZPR_1992	1.778e-41	159.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,1HYK9@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M1	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
TLS3_k127_5687396_0	755732.Fluta_2824	1.348e-19	89.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,1I50B@117743|Flavobacteriia,2PB90@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
TLS3_k127_5687396_1	435591.BDI_3541	1.366e-18	100.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,2FQU9@200643|Bacteroidia,22W8U@171551|Porphyromonadaceae	976|Bacteroidetes	G	Domain of unknown function (DUF5110)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,F5_F8_type_C,Gal_mutarotas_2,Glyco_hydro_31,fn3
TLS3_k127_5687396_2	1296416.JACB01000029_gene4180	1.551e-05	58.0	COG0265@1|root,COG0265@2|Bacteria,4PKT1@976|Bacteroidetes,1I89F@117743|Flavobacteriia,2YGTW@290174|Aquimarina	976|Bacteroidetes	O	Trypsin-like peptidase domain	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2,fn3
TLS3_k127_5687776_0	391587.KAOT1_05617	1.378e-201	651.0	COG0277@1|root,COG0277@2|Bacteria,4NHFC@976|Bacteroidetes,1HYJ4@117743|Flavobacteriia	976|Bacteroidetes	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,DUF805,FAD_binding_4
TLS3_k127_5687776_2	1336803.PHEL49_1312	1.181e-82	285.0	COG0657@1|root,COG0657@2|Bacteria,4NNWF@976|Bacteroidetes,1I0CN@117743|Flavobacteriia,3VV03@52959|Polaribacter	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase
TLS3_k127_5687776_1	1121373.KB903643_gene3586	1.618e-112	376.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,HisKA_7TM,Hpt,PMT_2,Response_reg
TLS3_k127_5687776_3	632335.Calkr_1515	5.801e-22	112.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia,42IJP@68295|Thermoanaerobacterales	186801|Clostridia	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,WG_beta_rep
TLS3_k127_5695519_2	1249997.JHZW01000003_gene3807	1.768e-38	148.0	COG3795@1|root,COG3795@2|Bacteria,4PPBG@976|Bacteroidetes	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
TLS3_k127_5695519_1	1121007.AUML01000006_gene3130	1.633e-63	226.0	COG2173@1|root,COG2173@2|Bacteria	2|Bacteria	M	zinc D-Ala-D-Ala carboxypeptidase activity	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
TLS3_k127_5695519_5	926562.Oweho_2970	0.0009594	44.0	2DFUX@1|root,2ZT8Y@2|Bacteria,4P92B@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5695519_0	1443665.JACA01000001_gene3025	5.605e-161	522.0	COG3210@1|root,COG3210@2|Bacteria,4NTNN@976|Bacteroidetes,1IKPF@117743|Flavobacteriia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP,SprB
TLS3_k127_5695519_3	1453498.LG45_04645	1.78e-07	64.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,1HYK9@117743|Flavobacteriia,2NUTR@237|Flavobacterium	976|Bacteroidetes	E	Peptidase M1	pepN1	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
TLS3_k127_5695519_4	1408813.AYMG01000033_gene5247	1.802e-07	53.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IPXM@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Resolvase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TLS3_k127_5712982_23	755732.Fluta_0096	1.446e-26	111.0	COG0346@1|root,COG0346@2|Bacteria,4NNNG@976|Bacteroidetes,1I1XF@117743|Flavobacteriia,2PB33@246874|Cryomorphaceae	976|Bacteroidetes	E	glyoxalase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
TLS3_k127_5712982_27	755732.Fluta_1938	5.703e-06	54.0	2A95M@1|root,30YA5@2|Bacteria,4PC1P@976|Bacteroidetes,1IMT1@117743|Flavobacteriia,2PC28@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5712982_21	1163617.SCD_n00657	1.721e-33	132.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,2VWVP@28216|Betaproteobacteria	28216|Betaproteobacteria	C	arsenate reductase	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
TLS3_k127_5712982_5	558152.IQ37_12440	1.825e-161	515.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,1HXZY@117743|Flavobacteriia,3ZQ53@59732|Chryseobacterium	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TLS3_k127_5712982_14	755732.Fluta_1933	1.09e-63	220.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1I1X5@117743|Flavobacteriia,2PAUI@246874|Cryomorphaceae	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
TLS3_k127_5712982_20	1408433.JHXV01000001_gene709	9.996e-34	138.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,1IGBV@117743|Flavobacteriia,2PB74@246874|Cryomorphaceae	976|Bacteroidetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_5712982_22	1408433.JHXV01000001_gene709	1.045e-30	131.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,1IGBV@117743|Flavobacteriia,2PB74@246874|Cryomorphaceae	976|Bacteroidetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_5712982_10	755732.Fluta_1927	4.894e-117	383.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
TLS3_k127_5712982_0	755732.Fluta_1926	4.519e-264	819.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia,2PBC6@246874|Cryomorphaceae	976|Bacteroidetes	C	Aldehyde dehydrogenase family	aldB	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_5712982_7	755732.Fluta_1925	8.291e-153	487.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes,1ICQK@117743|Flavobacteriia,2PBS2@246874|Cryomorphaceae	976|Bacteroidetes	F	DeoC/LacD family aldolase	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
TLS3_k127_5712982_11	755732.Fluta_1974	2.797e-97	325.0	COG2849@1|root,COG2849@2|Bacteria,4PG65@976|Bacteroidetes,1IMR5@117743|Flavobacteriia,2PBMX@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_5712982_8	755732.Fluta_1975	7.67e-149	476.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,1HWX0@117743|Flavobacteriia,2PA93@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	ltd	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS3_k127_5712982_2	1408433.JHXV01000014_gene3689	2.967e-216	675.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1HYHK@117743|Flavobacteriia,2PAA4@246874|Cryomorphaceae	976|Bacteroidetes	C	homogentisate 1,2-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
TLS3_k127_5712982_1	1197477.IA57_06290	1.114e-232	723.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1HWZ3@117743|Flavobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
TLS3_k127_5712982_16	755732.Fluta_0884	2.103e-54	199.0	COG4758@1|root,COG4758@2|Bacteria,4NQRE@976|Bacteroidetes,1IMSA@117743|Flavobacteriia,2PBW6@246874|Cryomorphaceae	976|Bacteroidetes	S	membrane protein (DUF2154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
TLS3_k127_5712982_17	755732.Fluta_0885	1.484e-53	201.0	COG2972@1|root,COG2972@2|Bacteria,4NI09@976|Bacteroidetes,1HY47@117743|Flavobacteriia,2PBP1@246874|Cryomorphaceae	976|Bacteroidetes	T	regulator of cell autolysis	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_5712982_12	700598.Niako_7013	6.012e-85	289.0	COG3279@1|root,COG3279@2|Bacteria,4NEAH@976|Bacteroidetes,1IQME@117747|Sphingobacteriia	976|Bacteroidetes	K	response regulator, receiver	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_5712982_4	1296416.JACB01000015_gene4652	1e-164	522.0	COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,1HWPD@117743|Flavobacteriia,2YGX9@290174|Aquimarina	976|Bacteroidetes	E	Tryptophan 2,3-dioxygenase	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
TLS3_k127_5712982_13	755732.Fluta_2036	4.269e-66	229.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,1HYJ9@117743|Flavobacteriia,2PASP@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
TLS3_k127_5712982_19	1223410.KN050846_gene1382	3.577e-35	147.0	COG2885@1|root,COG5295@1|root,COG2885@2|Bacteria,COG5295@2|Bacteria,4NN21@976|Bacteroidetes,1I1UJ@117743|Flavobacteriia	976|Bacteroidetes	UW	arginyl-trna synthetase	-	-	-	-	-	-	-	-	-	-	-	-	PA14
TLS3_k127_5712982_9	1237149.C900_05675	2.02e-130	430.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,47KTI@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised conserved protein UCP016719	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
TLS3_k127_5712982_6	755732.Fluta_2040	9.233e-155	509.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,1HWT5@117743|Flavobacteriia,2PATT@246874|Cryomorphaceae	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
TLS3_k127_5712982_26	189425.PGRAT_04260	1.071e-06	58.0	2F5PT@1|root,33Y8P@2|Bacteria,1VVNF@1239|Firmicutes,4I6XV@91061|Bacilli,26VGA@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5712982_25	1317122.ATO12_24330	7.341e-08	65.0	COG2373@1|root,COG3209@1|root,COG3210@1|root,COG2373@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia,2YIZM@290174|Aquimarina	976|Bacteroidetes	MU	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,HYR,SprB
TLS3_k127_5712982_15	1279009.ADICEAN_00688	2.556e-62	233.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
TLS3_k127_5712982_18	700598.Niako_2788	1.083e-52	198.0	COG3064@1|root,COG3064@2|Bacteria,4NM6Q@976|Bacteroidetes,1IQNW@117747|Sphingobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_5712982_24	269798.CHU_2925	5.555e-09	71.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
TLS3_k127_5712982_3	1341155.FSS13T_06640	6.303e-199	674.0	COG1572@1|root,COG3291@1|root,COG5492@1|root,COG1572@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NURE@237|Flavobacterium	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHU_C,HYR,SprB
TLS3_k127_5715225_1	755732.Fluta_2160	0.0	2281.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1HXXA@117743|Flavobacteriia,2PAEA@246874|Cryomorphaceae	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
TLS3_k127_5715225_0	755732.Fluta_2161	0.0	2440.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,1HYVS@117743|Flavobacteriia,2PACC@246874|Cryomorphaceae	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
TLS3_k127_5715225_4	755732.Fluta_2165	2.585e-37	143.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,1I323@117743|Flavobacteriia,2PB1G@246874|Cryomorphaceae	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
TLS3_k127_5715225_3	1408433.JHXV01000024_gene1481	2.817e-93	327.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1HXKD@117743|Flavobacteriia,2PBIT@246874|Cryomorphaceae	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_5715225_5	755732.Fluta_2172	1.925e-21	96.0	COG3027@1|root,COG3027@2|Bacteria,4NSA5@976|Bacteroidetes,1I41M@117743|Flavobacteriia,2PB8C@246874|Cryomorphaceae	976|Bacteroidetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
TLS3_k127_5715225_2	755732.Fluta_2173	6.595e-133	430.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,1HYHI@117743|Flavobacteriia,2PA4M@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF3552)	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
TLS3_k127_57187_0	755732.Fluta_2702	3.903e-196	616.0	COG2159@1|root,COG2159@2|Bacteria,4NIGJ@976|Bacteroidetes,1HZPW@117743|Flavobacteriia,2PB6Q@246874|Cryomorphaceae	976|Bacteroidetes	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
TLS3_k127_57187_1	755732.Fluta_2945	1.898e-95	331.0	COG2931@1|root,COG3291@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,4NDZC@976|Bacteroidetes,1IKDY@117743|Flavobacteriia,2PC6N@246874|Cryomorphaceae	976|Bacteroidetes	U	SPTR Conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA,SprB
TLS3_k127_5719970_2	755732.Fluta_1434	7.657e-57	201.0	COG4261@1|root,COG4261@2|Bacteria,4NF49@976|Bacteroidetes,1HXDQ@117743|Flavobacteriia,2PAQR@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
TLS3_k127_5719970_3	269798.CHU_2120	3.791e-19	93.0	COG0764@1|root,COG0764@2|Bacteria,4PKBK@976|Bacteroidetes,47RZR@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5719970_1	755732.Fluta_1436	6.149e-57	201.0	COG0824@1|root,COG0824@2|Bacteria,4NRHH@976|Bacteroidetes,1I3DP@117743|Flavobacteriia,2PAZP@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
TLS3_k127_5719970_0	1121481.AUAS01000005_gene1792	1.983e-107	359.0	COG0304@1|root,COG0304@2|Bacteria,4NE8K@976|Bacteroidetes,47PEB@768503|Cytophagia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, C-terminal domain	fabF2	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_5749895_2	755732.Fluta_2412	2.687e-69	241.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1HX11@117743|Flavobacteriia,2PB20@246874|Cryomorphaceae	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	fjo14	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
TLS3_k127_5749895_3	755732.Fluta_2411	1.635e-30	123.0	COG1359@1|root,COG1359@2|Bacteria,4NSV0@976|Bacteroidetes,1I40Y@117743|Flavobacteriia,2PB7G@246874|Cryomorphaceae	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
TLS3_k127_5749895_1	755732.Fluta_2410	1.894e-97	324.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,1HX1M@117743|Flavobacteriia,2PAR7@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
TLS3_k127_5749895_0	755732.Fluta_2409	7.953e-213	676.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1HX9X@117743|Flavobacteriia,2PAPC@246874|Cryomorphaceae	976|Bacteroidetes	N	ABC-type uncharacterized transport system	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
TLS3_k127_576274_4	95619.PM1_0221810	4.904e-44	163.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
TLS3_k127_576274_5	755732.Fluta_2260	2.087e-38	151.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K12057	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	Thioredoxin,TraF
TLS3_k127_576274_2	755732.Fluta_0745	7.757e-71	258.0	28M10@1|root,2ZAFW@2|Bacteria,4NIF8@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4403)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4403
TLS3_k127_576274_6	269798.CHU_3575	6.671e-36	139.0	COG2346@1|root,COG2346@2|Bacteria,4NTJR@976|Bacteroidetes,47RRK@768503|Cytophagia	976|Bacteroidetes	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
TLS3_k127_576274_3	755732.Fluta_0746	1.926e-54	206.0	COG2885@1|root,COG2885@2|Bacteria,4PISD@976|Bacteroidetes,1ICSE@117743|Flavobacteriia,2PBZT@246874|Cryomorphaceae	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_576274_7	1121935.AQXX01000088_gene4706	7.667e-18	87.0	2CD9R@1|root,2ZRYM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_576274_1	755732.Fluta_2479	1.192e-74	256.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,1HYRH@117743|Flavobacteriia,2PARK@246874|Cryomorphaceae	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
TLS3_k127_576274_0	755732.Fluta_2478	4.028e-124	399.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1HXVS@117743|Flavobacteriia,2PAHN@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
TLS3_k127_5777334_0	1443665.JACA01000005_gene355	1.45e-191	607.0	COG0402@1|root,COG0402@2|Bacteria,4NG64@976|Bacteroidetes,1I0FD@117743|Flavobacteriia,2YJ9A@290174|Aquimarina	976|Bacteroidetes	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
TLS3_k127_584076_6	1123057.P872_18240	1.21e-25	109.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,47K7C@768503|Cytophagia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
TLS3_k127_584076_4	755732.Fluta_2286	9.029e-135	439.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1HWNN@117743|Flavobacteriia,2PAD0@246874|Cryomorphaceae	976|Bacteroidetes	E	Arginase family	fjo29	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS3_k127_584076_5	755732.Fluta_2287	6.942e-91	308.0	COG0729@1|root,COG0729@2|Bacteria,4PP0N@976|Bacteroidetes,1IKDS@117743|Flavobacteriia,2PAY8@246874|Cryomorphaceae	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_584076_0	755732.Fluta_2288	5.707e-304	935.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1HXXN@117743|Flavobacteriia,2PAKH@246874|Cryomorphaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TLS3_k127_584076_2	755732.Fluta_2289	3.368e-142	456.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,1HYV7@117743|Flavobacteriia,2PAW7@246874|Cryomorphaceae	976|Bacteroidetes	S	Gliding motility protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_584076_1	755732.Fluta_2293	1.102e-171	556.0	28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,1HWV7@117743|Flavobacteriia,2PB05@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM gliding motility-associated protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
TLS3_k127_584076_3	755732.Fluta_2291	2.589e-135	438.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,1HX8Y@117743|Flavobacteriia,2PAWJ@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM gliding motility associated protien GldN	gldN	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5877515_4	3055.EDP05720	4.983e-18	94.0	COG5253@1|root,KOG0229@2759|Eukaryota,37WD5@33090|Viridiplantae,34M3I@3041|Chlorophyta	3041|Chlorophyta	T	Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases.	-	-	-	-	-	-	-	-	-	-	-	-	MORN
TLS3_k127_5877515_2	1408813.AYMG01000015_gene5030	1.091e-39	153.0	COG0454@1|root,COG0454@2|Bacteria,4NWCY@976|Bacteroidetes,1IYX6@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
TLS3_k127_5877515_3	391603.FBALC1_07418	8.103e-27	120.0	2AZZY@1|root,31SA0@2|Bacteria,4NRJ3@976|Bacteroidetes,1I3N5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5877515_1	1178825.ALIH01000012_gene1815	4.513e-72	253.0	COG0745@1|root,COG0745@2|Bacteria,4NIKR@976|Bacteroidetes,1HYDZ@117743|Flavobacteriia	976|Bacteroidetes	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
TLS3_k127_5877515_5	143224.JQMD01000002_gene3578	3.487e-05	47.0	29VE2@1|root,30GUS@2|Bacteria,4NP29@976|Bacteroidetes,1I29M@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5877515_0	1123248.KB893328_gene922	2.09e-107	356.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1IW53@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_5911965_0	755732.Fluta_1812	0.0	1261.0	COG3536@1|root,COG3536@2|Bacteria,4PKQ9@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5911965_4	1237149.C900_02720	4.538e-15	82.0	COG2825@1|root,COG2825@2|Bacteria,4NQHJ@976|Bacteroidetes,47QWE@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane protein (OmpH-like)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TLS3_k127_5911965_1	755732.Fluta_1403	5.19e-171	552.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,1HZPN@117743|Flavobacteriia,2PBIP@246874|Cryomorphaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_5911965_2	755732.Fluta_1402	2.055e-101	334.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,1IISG@117743|Flavobacteriia,2PARV@246874|Cryomorphaceae	976|Bacteroidetes	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_5911965_3	1168034.FH5T_06745	2.324e-90	315.0	COG2244@1|root,COG2244@2|Bacteria,4NPGZ@976|Bacteroidetes,2G3BA@200643|Bacteroidia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
TLS3_k127_5918204_5	755732.Fluta_1213	2.159e-80	297.0	COG1112@1|root,COG1112@2|Bacteria,4NF2S@976|Bacteroidetes,1I1IU@117743|Flavobacteriia,2PBBT@246874|Cryomorphaceae	976|Bacteroidetes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011,WGR
TLS3_k127_5918204_1	1408433.JHXV01000016_gene1827	4.373e-198	623.0	COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,1HXPE@117743|Flavobacteriia,2PA8D@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Cys Met metabolism PLP-dependent enzyme	metC	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
TLS3_k127_5918204_6	643867.Ftrac_2536	8.744e-72	249.0	COG0569@1|root,COG0569@2|Bacteria,4NGRQ@976|Bacteroidetes,47PBV@768503|Cytophagia	976|Bacteroidetes	P	TrkA-N domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
TLS3_k127_5918204_7	755732.Fluta_1215	2.355e-41	162.0	COG1028@1|root,COG1028@2|Bacteria,4NNJ9@976|Bacteroidetes,1I53I@117743|Flavobacteriia,2PB0V@246874|Cryomorphaceae	976|Bacteroidetes	IQ	PFAM short chain dehydrogenase	yueD	-	1.1.1.320	ko:K16216	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
TLS3_k127_5918204_0	755732.Fluta_1217	9.307e-211	676.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2PBDM@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
TLS3_k127_5918204_2	755732.Fluta_1217	6.591e-185	601.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2PBDM@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
TLS3_k127_5918204_8	755732.Fluta_1456	1.415e-35	144.0	COG1587@1|root,COG1587@2|Bacteria,4PACB@976|Bacteroidetes,1IMTA@117743|Flavobacteriia,2PC3Y@246874|Cryomorphaceae	976|Bacteroidetes	H	Uroporphyrinogen-III synthase HemD	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
TLS3_k127_5918204_4	755732.Fluta_1457	2.212e-110	364.0	COG0181@1|root,COG0181@2|Bacteria,4NHH4@976|Bacteroidetes,1HXKZ@117743|Flavobacteriia,2PB12@246874|Cryomorphaceae	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
TLS3_k127_5918204_3	755732.Fluta_1458	2.122e-143	466.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1HX42@117743|Flavobacteriia,2PB3M@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
TLS3_k127_5923258_0	755732.Fluta_1428	1.158e-211	672.0	COG1233@1|root,COG1233@2|Bacteria,4P24Z@976|Bacteroidetes,1IITR@117743|Flavobacteriia	976|Bacteroidetes	C	COGs COG1233 Phytoene dehydrogenase and related protein	-	-	5.2.1.13	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R07512	RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	-
TLS3_k127_5923258_1	755732.Fluta_1429	1.043e-108	357.0	COG0500@1|root,COG2226@2|Bacteria,4NGN8@976|Bacteroidetes,1IK35@117743|Flavobacteriia,2PAH3@246874|Cryomorphaceae	976|Bacteroidetes	H	O-methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
TLS3_k127_5923985_10	755732.Fluta_0195	9.954e-42	158.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	yiiD	-	-	-	-	-	-	-	-	-	-	-	4HBT,DUF4442,YiiD_C
TLS3_k127_5923985_5	755732.Fluta_0196	1.016e-124	407.0	COG2070@1|root,COG2070@2|Bacteria,4NFIW@976|Bacteroidetes,1HY76@117743|Flavobacteriia,2PBER@246874|Cryomorphaceae	976|Bacteroidetes	S	Thiazole biosynthesis protein ThiG	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
TLS3_k127_5923985_7	755732.Fluta_0199	3.459e-82	282.0	COG1575@1|root,COG1575@2|Bacteria,4NGCJ@976|Bacteroidetes,1HWR2@117743|Flavobacteriia,2PAR8@246874|Cryomorphaceae	976|Bacteroidetes	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
TLS3_k127_5923985_6	755732.Fluta_0200	1.003e-113	377.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,1HY3V@117743|Flavobacteriia,2PAKI@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal domain	menC	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
TLS3_k127_5923985_0	755732.Fluta_2354	0.0	1029.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,1HXWN@117743|Flavobacteriia,2PACV@246874|Cryomorphaceae	976|Bacteroidetes	K	TIGRFAM competence protein ComEA helix-hairpin-helix repeat region	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
TLS3_k127_5923985_14	1236542.BALM01000003_gene699	2.225e-05	51.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RMVE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.2.3	ko:K07812	-	-	-	-	ko00000,ko01000,ko02000	5.A.3.4	-	-	Molybdopterin,Molydop_binding,TAT_signal
TLS3_k127_5923985_12	1270193.JARP01000001_gene2388	3.154e-13	74.0	COG2010@1|root,COG2010@2|Bacteria,4NXZT@976|Bacteroidetes,1I673@117743|Flavobacteriia,2NX4B@237|Flavobacterium	976|Bacteroidetes	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHC
TLS3_k127_5923985_4	1408445.JHXP01000007_gene458	2.974e-141	456.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,1JDNA@118969|Legionellales	118969|Legionellales	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
TLS3_k127_5923985_9	755732.Fluta_2351	3.051e-50	182.0	COG0454@1|root,COG0456@2|Bacteria,4NU41@976|Bacteroidetes	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
TLS3_k127_5923985_8	755732.Fluta_2422	2.643e-69	239.0	29BEQ@1|root,2ZYD2@2|Bacteria,4PD0R@976|Bacteroidetes,1ICRX@117743|Flavobacteriia,2PBXT@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5923985_13	391603.FBALC1_16707	1.991e-10	72.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Reprolysin_3,Reprolysin_4,Reprolysin_5
TLS3_k127_5923985_11	1408433.JHXV01000021_gene1703	2.852e-19	99.0	COG0526@1|root,COG0526@2|Bacteria,4NNXC@976|Bacteroidetes,1I2AF@117743|Flavobacteriia	976|Bacteroidetes	CO	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Omp28,Thioredoxin
TLS3_k127_5923985_2	1408433.JHXV01000021_gene1703	4.54e-162	532.0	COG0526@1|root,COG0526@2|Bacteria,4NNXC@976|Bacteroidetes,1I2AF@117743|Flavobacteriia	976|Bacteroidetes	CO	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Omp28,Thioredoxin
TLS3_k127_5923985_1	1408433.JHXV01000001_gene1075	3.108e-180	570.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1HWZT@117743|Flavobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
TLS3_k127_5923985_3	755732.Fluta_2423	5.439e-157	509.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1I7ZV@117743|Flavobacteriia,2PAMN@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
TLS3_k127_5962560_9	755732.Fluta_2208	2.735e-63	224.0	COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,1HXSX@117743|Flavobacteriia,2PAIJ@246874|Cryomorphaceae	976|Bacteroidetes	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
TLS3_k127_5962560_3	755732.Fluta_2209	1.994e-195	620.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1HXA8@117743|Flavobacteriia,2PA7Z@246874|Cryomorphaceae	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_5962560_0	755732.Fluta_2211	9.568e-220	686.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1HWY5@117743|Flavobacteriia,2PAGT@246874|Cryomorphaceae	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
TLS3_k127_5962560_1	755732.Fluta_2212	1.706e-200	632.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1HX80@117743|Flavobacteriia,2PAFV@246874|Cryomorphaceae	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
TLS3_k127_5962560_5	755732.Fluta_2214	3.958e-155	499.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1HWQM@117743|Flavobacteriia,2PAVJ@246874|Cryomorphaceae	976|Bacteroidetes	D	Cell cycle protein	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
TLS3_k127_5962560_7	755732.Fluta_2215	3.062e-134	436.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,1HXPU@117743|Flavobacteriia,2PAIY@246874|Cryomorphaceae	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
TLS3_k127_5962560_6	1408433.JHXV01000032_gene1128	9.119e-136	445.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1HX68@117743|Flavobacteriia,2PAJC@246874|Cryomorphaceae	976|Bacteroidetes	M	Mur ligase family, catalytic domain	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_5962560_8	755732.Fluta_2217	2.4e-64	229.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,1ICB3@117743|Flavobacteriia,2PB7Z@246874|Cryomorphaceae	976|Bacteroidetes	M	Cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
TLS3_k127_5962560_2	755732.Fluta_2221	8.677e-200	629.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1HY6Y@117743|Flavobacteriia,2PA5T@246874|Cryomorphaceae	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
TLS3_k127_5962560_4	1408433.JHXV01000032_gene1131	1.337e-166	529.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1HWTE@117743|Flavobacteriia,2PADU@246874|Cryomorphaceae	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
TLS3_k127_6020290_3	755732.Fluta_3251	3.577e-57	203.0	COG1670@1|root,COG1670@2|Bacteria,4PI5M@976|Bacteroidetes,1IG53@117743|Flavobacteriia,2PBSU@246874|Cryomorphaceae	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
TLS3_k127_6020290_1	1122176.KB903536_gene1761	1.778e-166	539.0	28KN2@1|root,2ZA6D@2|Bacteria,4NG7P@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6020290_5	755732.Fluta_0325	2.362e-13	80.0	2A8BJ@1|root,30XD4@2|Bacteria,4PAT3@976|Bacteroidetes,1I6G9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6020290_6	1349822.NSB1T_03915	4.811e-09	69.0	COG2067@1|root,COG2067@2|Bacteria,4NVVD@976|Bacteroidetes,2FQRB@200643|Bacteroidia,23101@171551|Porphyromonadaceae	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_6020290_2	867900.Celly_2806	1.057e-81	282.0	COG1975@1|root,COG1975@2|Bacteria,4NG02@976|Bacteroidetes,1HXMQ@117743|Flavobacteriia,1F91A@104264|Cellulophaga	976|Bacteroidetes	O	COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
TLS3_k127_6020290_0	388413.ALPR1_12120	1.842e-225	708.0	COG3511@1|root,COG3511@2|Bacteria,4NNZX@976|Bacteroidetes	976|Bacteroidetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
TLS3_k127_6029937_0	755732.Fluta_2011	5.45e-321	992.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1HXZE@117743|Flavobacteriia,2PAAI@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
TLS3_k127_6029937_3	755732.Fluta_2010	7.797e-68	241.0	COG0642@1|root,COG2205@2|Bacteria,4NK58@976|Bacteroidetes,1IMRI@117743|Flavobacteriia,2PBQM@246874|Cryomorphaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_6029937_1	755732.Fluta_2009	3.634e-211	669.0	COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,1HWJU@117743|Flavobacteriia,2PA89@246874|Cryomorphaceae	976|Bacteroidetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
TLS3_k127_6029937_5	755732.Fluta_0889	1.782e-62	218.0	COG0615@1|root,COG0615@2|Bacteria,4NNKK@976|Bacteroidetes,1IFSR@117743|Flavobacteriia,2PBPT@246874|Cryomorphaceae	976|Bacteroidetes	IM	Cytidylyltransferase-like	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like
TLS3_k127_6029937_4	143224.JQMD01000002_gene2849	5.005e-63	228.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1HXYD@117743|Flavobacteriia	976|Bacteroidetes	S	integral membrane protein	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
TLS3_k127_6029937_6	1122981.AUME01000046_gene1636	2.999e-49	178.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,2FSH0@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
TLS3_k127_6029937_2	755732.Fluta_0892	6.052e-74	255.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,1HXD5@117743|Flavobacteriia,2PAMU@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
TLS3_k127_6038161_6	1249997.JHZW01000003_gene3524	5.487e-17	90.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1I1B3@117743|Flavobacteriia,2PH0R@252356|Maribacter	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
TLS3_k127_6038161_0	1120968.AUBX01000012_gene2797	1.969e-232	743.0	COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
TLS3_k127_6038161_2	1048983.EL17_18920	3.67e-75	276.0	COG3078@1|root,COG3078@2|Bacteria,4NIGK@976|Bacteroidetes,47K8U@768503|Cytophagia	976|Bacteroidetes	P	GTPase activator activity	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_6038161_5	485918.Cpin_6759	3.953e-26	120.0	COG3712@1|root,COG3712@2|Bacteria,4NMA2@976|Bacteroidetes,1IS2K@117747|Sphingobacteriia	976|Bacteroidetes	PT	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR
TLS3_k127_6038161_4	761193.Runsl_2080	2.515e-38	149.0	COG1595@1|root,COG1595@2|Bacteria,4NNBY@976|Bacteroidetes,47PH5@768503|Cytophagia	976|Bacteroidetes	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_6038161_3	755732.Fluta_2090	3.3e-63	238.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_6038161_1	382464.ABSI01000010_gene3298	4.9e-76	267.0	COG4978@1|root,COG4978@2|Bacteria,46Z73@74201|Verrucomicrobia,2IWQA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_6081010_9	1121889.AUDM01000006_gene1622	1.791e-06	50.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1HXZ2@117743|Flavobacteriia,2NSMF@237|Flavobacterium	976|Bacteroidetes	H	synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
TLS3_k127_6081010_8	1408433.JHXV01000041_gene3598	6.546e-22	100.0	COG0848@1|root,COG0848@2|Bacteria,4PJUV@976|Bacteroidetes,1IGG3@117743|Flavobacteriia,2PB9F@246874|Cryomorphaceae	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
TLS3_k127_6081010_6	1408433.JHXV01000041_gene3597	1.448e-63	226.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,1HXWI@117743|Flavobacteriia,2PB0P@246874|Cryomorphaceae	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
TLS3_k127_6081010_3	886377.Murru_0758	6.08e-181	576.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,1HYB2@117743|Flavobacteriia	976|Bacteroidetes	P	Na H antiporter NhaD and related arsenite	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
TLS3_k127_6081010_1	755732.Fluta_2544	5.852e-225	702.0	COG0334@1|root,COG0334@2|Bacteria,4NG6Y@976|Bacteroidetes,1HXP5@117743|Flavobacteriia,2PA4X@246874|Cryomorphaceae	976|Bacteroidetes	C	Glu Leu Phe Val dehydrogenase, dimerisation domain	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
TLS3_k127_6081010_5	755732.Fluta_2545	4.947e-107	357.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,1HWX7@117743|Flavobacteriia,2PAP3@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
TLS3_k127_6081010_2	755732.Fluta_2546	3.769e-213	665.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1HWV4@117743|Flavobacteriia,2PAB6@246874|Cryomorphaceae	976|Bacteroidetes	C	Acyl-CoA dehydrogenase, N-terminal domain	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_6081010_4	1408433.JHXV01000041_gene3592	1.628e-129	426.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1HY7Q@117743|Flavobacteriia,2PA7M@246874|Cryomorphaceae	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_6081010_0	755732.Fluta_2548	0.0	1060.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1HXGH@117743|Flavobacteriia,2PA9N@246874|Cryomorphaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TLS3_k127_6081010_7	755732.Fluta_2549	7.854e-48	172.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1HZRC@117743|Flavobacteriia,2PANF@246874|Cryomorphaceae	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_6107557_2	755732.Fluta_0273	1.005e-25	109.0	COG2921@1|root,COG2921@2|Bacteria,4PA5G@976|Bacteroidetes,1IGIZ@117743|Flavobacteriia,2PB80@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF493)	-	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
TLS3_k127_6107557_0	755732.Fluta_0271	5.595e-57	199.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1I2SS@117743|Flavobacteriia,2PAZU@246874|Cryomorphaceae	976|Bacteroidetes	O	Thioredoxin-like domain	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
TLS3_k127_6107557_1	755732.Fluta_0270	1.286e-46	177.0	2ABK4@1|root,3111J@2|Bacteria,4PFQS@976|Bacteroidetes,1IGIS@117743|Flavobacteriia,2PB9T@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6107557_4	746697.Aeqsu_2648	4.453e-10	61.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1HWJD@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
TLS3_k127_611386_6	760192.Halhy_5051	1.075e-47	178.0	COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,1IRNF@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_611386_5	929556.Solca_0088	2.344e-51	190.0	COG3279@1|root,COG3279@2|Bacteria,4NI3K@976|Bacteroidetes,1J04H@117747|Sphingobacteriia	976|Bacteroidetes	K	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_611386_7	391587.KAOT1_20322	1.015e-39	154.0	COG0500@1|root,COG2226@2|Bacteria,4PKP0@976|Bacteroidetes,1IJW3@117743|Flavobacteriia	976|Bacteroidetes	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_611386_1	1223410.KN050846_gene61	8.72e-101	340.0	COG3781@1|root,COG3781@2|Bacteria,4NGJ0@976|Bacteroidetes,1HYG9@117743|Flavobacteriia	976|Bacteroidetes	S	Multidrug transporter	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
TLS3_k127_611386_3	760192.Halhy_5493	3.53e-76	258.0	2F17F@1|root,33U8J@2|Bacteria,4P2WT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_611386_4	449447.MAE_26250	1.939e-65	230.0	COG3757@1|root,COG3757@2|Bacteria,1G8V0@1117|Cyanobacteria	1117|Cyanobacteria	M	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906
TLS3_k127_611386_9	1484460.JSWG01000004_gene2569	0.0002934	48.0	COG1404@1|root,COG1404@2|Bacteria,4NRWQ@976|Bacteroidetes,1I3TQ@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_611386_8	755732.Fluta_3357	1.26e-11	67.0	COG1357@1|root,COG1357@2|Bacteria,4PNZS@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
TLS3_k127_611386_0	1286632.P278_00160	1.129e-307	947.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,1HWMM@117743|Flavobacteriia	976|Bacteroidetes	S	of ABC transporters with duplicated ATPase	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_611386_2	1239415.CM001837_gene1582	3.629e-80	273.0	COG3608@1|root,COG3608@2|Bacteria,4NE8S@976|Bacteroidetes,1HXAJ@117743|Flavobacteriia,37FH6@326319|Dokdonia	976|Bacteroidetes	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
TLS3_k127_6139010_2	755732.Fluta_1184	1.138e-188	600.0	COG3474@1|root,COG3474@2|Bacteria,4PKQA@976|Bacteroidetes,1I8RP@117743|Flavobacteriia,2PAPE@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
TLS3_k127_6139010_0	755732.Fluta_1183	0.0	1412.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1HWY0@117743|Flavobacteriia,2PA5H@246874|Cryomorphaceae	976|Bacteroidetes	C	4Fe-4S dicluster domain	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
TLS3_k127_6139010_1	755732.Fluta_1182	1.059e-298	919.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia,2PABZ@246874|Cryomorphaceae	976|Bacteroidetes	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
TLS3_k127_6139010_3	755732.Fluta_1181	1.453e-79	267.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1HXN6@117743|Flavobacteriia,2PAX8@246874|Cryomorphaceae	976|Bacteroidetes	C	Protein of unknown function (DUF3341)	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
TLS3_k127_615044_4	755732.Fluta_3801	5.4e-38	144.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1HWMB@117743|Flavobacteriia,2PAJU@246874|Cryomorphaceae	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
TLS3_k127_615044_2	755732.Fluta_1562	9.236e-49	181.0	COG1595@1|root,COG1595@2|Bacteria,4NT79@976|Bacteroidetes,1IIVT@117743|Flavobacteriia,2PC03@246874|Cryomorphaceae	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_615044_0	755732.Fluta_1563	1.482e-92	317.0	COG1262@1|root,COG1262@2|Bacteria,4PI07@976|Bacteroidetes,1ICQR@117743|Flavobacteriia,2PBSV@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_615044_6	592029.DDD_0913	9.251e-18	96.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1IE6U@117743|Flavobacteriia,3HKW6@363408|Nonlabens	976|Bacteroidetes	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
TLS3_k127_615044_1	1408433.JHXV01000001_gene818	6.018e-74	258.0	COG2207@1|root,COG2207@2|Bacteria,4PI70@976|Bacteroidetes,1I7GK@117743|Flavobacteriia,2PBZK@246874|Cryomorphaceae	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
TLS3_k127_615044_5	755732.Fluta_3638	4.816e-19	92.0	COG1826@1|root,COG1826@2|Bacteria,4PFQQ@976|Bacteroidetes,1IGIP@117743|Flavobacteriia,2PBA1@246874|Cryomorphaceae	976|Bacteroidetes	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
TLS3_k127_615044_3	755732.Fluta_3165	1.211e-42	161.0	COG2050@1|root,COG2050@2|Bacteria,4P9RP@976|Bacteroidetes,1IE1G@117743|Flavobacteriia,2PC33@246874|Cryomorphaceae	976|Bacteroidetes	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
TLS3_k127_6153109_0	1349785.BAUG01000004_gene331	5.795e-93	318.0	COG2267@1|root,COG2267@2|Bacteria,4NK38@976|Bacteroidetes,1HX88@117743|Flavobacteriia	976|Bacteroidetes	I	Protein of unknown function (DUF3089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3089
TLS3_k127_6153109_2	643867.Ftrac_2348	6.827e-21	95.0	COG4895@1|root,COG4895@2|Bacteria,4NUT0@976|Bacteroidetes,47RYA@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2196)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2196
TLS3_k127_6153109_1	945713.IALB_2314	1.037e-51	210.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
TLS3_k127_6153109_3	1121957.ATVL01000001_gene3499	2.627e-19	104.0	COG1409@1|root,COG2755@1|root,COG3209@1|root,COG1409@2|Bacteria,COG2755@2|Bacteria,COG3209@2|Bacteria,4P1IQ@976|Bacteroidetes,47UTQ@768503|Cytophagia	2|Bacteria	M	COG3209 Rhs family protein	yhcR	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	ChitinaseA_N
TLS3_k127_6153109_4	485918.Cpin_2962	4.43e-07	64.0	COG1520@1|root,COG3291@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,4NRDH@976|Bacteroidetes,1IWXM@117747|Sphingobacteriia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_6167240_2	755732.Fluta_3659	3.68e-43	169.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	GSDH,PQQ_2
TLS3_k127_6167240_0	755732.Fluta_3660	4.5e-140	448.0	COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,1IMQP@117743|Flavobacteriia,2PBFH@246874|Cryomorphaceae	976|Bacteroidetes	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
TLS3_k127_6167240_1	755732.Fluta_3661	6.973e-137	449.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1HXHP@117743|Flavobacteriia,2PAVT@246874|Cryomorphaceae	976|Bacteroidetes	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
TLS3_k127_6180149_3	1121931.AUHG01000011_gene2210	7.48e-06	52.0	COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,1HXVP@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
TLS3_k127_6180149_0	760192.Halhy_4220	5.45e-133	444.0	COG3291@1|root,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes	976|Bacteroidetes	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	PKD,UnbV_ASPIC,VCBS
TLS3_k127_6180149_2	376686.Fjoh_2226	3.829e-09	61.0	COG0793@1|root,COG0793@2|Bacteria,4NEFX@976|Bacteroidetes,1HZ4U@117743|Flavobacteriia,2NW73@237|Flavobacterium	976|Bacteroidetes	M	Peptidase family S41	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41,Tricorn_C1
TLS3_k127_6180149_1	102125.Xen7305DRAFT_00006940	3.048e-17	89.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
TLS3_k127_6187953_2	1122226.AUHX01000009_gene2824	1.611e-17	91.0	2DGA4@1|root,2ZV3E@2|Bacteria,4NP9P@976|Bacteroidetes,1I2DI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6187953_1	1408433.JHXV01000006_gene2762	8.46e-18	95.0	COG3394@1|root,COG3394@2|Bacteria,4P7KM@976|Bacteroidetes	976|Bacteroidetes	G	YdjC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YdjC
TLS3_k127_6187953_0	391587.KAOT1_05772	3.561e-60	214.0	COG0501@1|root,COG0501@2|Bacteria,4NFV7@976|Bacteroidetes,1HZQY@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TLS3_k127_6192761_3	319236.JCM19294_1298	6.483e-51	189.0	COG0512@1|root,COG0512@2|Bacteria,4NE4I@976|Bacteroidetes,1HWU0@117743|Flavobacteriia,3HJD8@363408|Nonlabens	976|Bacteroidetes	EH	Peptidase C26	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
TLS3_k127_6192761_4	755732.Fluta_2653	7.187e-50	181.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,1I2YH@117743|Flavobacteriia,2PAYG@246874|Cryomorphaceae	976|Bacteroidetes	J	Endoribonuclease L-PSP	yjgF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
TLS3_k127_6192761_1	755732.Fluta_2652	4.55e-217	691.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,1HWKX@117743|Flavobacteriia,2PA5Z@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_6192761_2	755732.Fluta_2651	8.174e-205	646.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1HWW8@117743|Flavobacteriia,2PA51@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM 2-oxoacid dehydrogenases acyltransferase (catalytic domain)	bfmBB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS3_k127_6192761_0	755732.Fluta_2650	1.572e-223	716.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4P15I@976|Bacteroidetes,1IE72@117743|Flavobacteriia,2PBDD@246874|Cryomorphaceae	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
TLS3_k127_6194406_23	755732.Fluta_0325	4.596e-11	72.0	2A8BJ@1|root,30XD4@2|Bacteria,4PAT3@976|Bacteroidetes,1I6G9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6194406_25	1408823.AXUS01000008_gene2298	1.356e-07	58.0	COG3409@1|root,COG3409@2|Bacteria,1VGC4@1239|Firmicutes,24R4H@186801|Clostridia	186801|Clostridia	M	Flagellar rod assembly protein muramidase FlgJ	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,PG_binding_1
TLS3_k127_6194406_18	1233950.IW22_19390	1.77e-25	117.0	2DPCB@1|root,331HJ@2|Bacteria,4NVHA@976|Bacteroidetes,1I52T@117743|Flavobacteriia,3ZUHH@59732|Chryseobacterium	976|Bacteroidetes	S	Putative phage abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	putAbiC
TLS3_k127_6194406_20	313595.P700755_003938	2.263e-23	103.0	COG4096@1|root,COG4096@2|Bacteria,4NH89@976|Bacteroidetes,1HYP2@117743|Flavobacteriia	976|Bacteroidetes	L	Type I site-specific restriction-modification system, R (restriction) subunit and related	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
TLS3_k127_6194406_21	1122975.AQVC01000016_gene1777	4.02e-21	98.0	COG0810@1|root,COG0810@2|Bacteria,4NW2E@976|Bacteroidetes,2FWGT@200643|Bacteroidia,23228@171551|Porphyromonadaceae	976|Bacteroidetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
TLS3_k127_6194406_17	760192.Halhy_4483	1.412e-28	134.0	2B31B@1|root,31VNR@2|Bacteria,4NS4U@976|Bacteroidetes,1ITM6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6194406_26	929506.CbC4_1689	7.37e-06	56.0	COG0265@1|root,COG0265@2|Bacteria,1TRQS@1239|Firmicutes	1239|Firmicutes	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S7,Trypsin
TLS3_k127_6194406_12	391598.FBBAL38_11079	9.031e-38	151.0	COG3137@1|root,COG3137@2|Bacteria,4NJH6@976|Bacteroidetes,1HYK0@117743|Flavobacteriia	976|Bacteroidetes	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
TLS3_k127_6194406_16	471854.Dfer_0663	2.987e-32	145.0	COG1361@1|root,COG1361@2|Bacteria,4NT9E@976|Bacteroidetes,47QTN@768503|Cytophagia	976|Bacteroidetes	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
TLS3_k127_6194406_4	755732.Fluta_2892	4.418e-171	544.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	M60-like_N,PD40,Peptidase_M60
TLS3_k127_6194406_8	1408433.JHXV01000007_gene2811	2.091e-111	368.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,1HYH4@117743|Flavobacteriia,2PB5X@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaQ	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
TLS3_k127_6194406_9	1117314.PCIT_07282	4.494e-78	285.0	COG3511@1|root,COG3511@2|Bacteria,1MWVP@1224|Proteobacteria,1RRZZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	phospholipase C	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	DUF756,Phosphoesterase
TLS3_k127_6194406_14	1237149.C900_05678	1.971e-34	135.0	COG0526@1|root,COG0526@2|Bacteria,4PKQI@976|Bacteroidetes,47XZ0@768503|Cytophagia	976|Bacteroidetes	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
TLS3_k127_6194406_0	1484460.JSWG01000012_gene1559	0.0	1234.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1HWN8@117743|Flavobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
TLS3_k127_6194406_24	485917.Phep_1531	1.292e-07	63.0	COG3064@1|root,COG3064@2|Bacteria,4NM6Q@976|Bacteroidetes,1IQNW@117747|Sphingobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_6194406_19	1408433.JHXV01000005_gene2453	9.584e-25	108.0	COG5349@1|root,COG5349@2|Bacteria,4P5AM@976|Bacteroidetes,1IACF@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
TLS3_k127_6194406_2	755732.Fluta_1253	2.646e-272	841.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1HXDC@117743|Flavobacteriia,2PADR@246874|Cryomorphaceae	976|Bacteroidetes	I	PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
TLS3_k127_6194406_10	755732.Fluta_1252	7.126e-60	210.0	COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,1I1AS@117743|Flavobacteriia,2PAVR@246874|Cryomorphaceae	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
TLS3_k127_6194406_3	755732.Fluta_1251	7.013e-181	570.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1HX72@117743|Flavobacteriia,2PA6K@246874|Cryomorphaceae	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
TLS3_k127_6194406_6	755732.Fluta_1250	1.963e-153	489.0	COG0416@1|root,COG0416@2|Bacteria,4NHEX@976|Bacteroidetes,1IMQV@117743|Flavobacteriia,2PBGV@246874|Cryomorphaceae	976|Bacteroidetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
TLS3_k127_6194406_15	755732.Fluta_1249	2.681e-32	125.0	COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,1I53M@117743|Flavobacteriia,2PB5W@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
TLS3_k127_6194406_11	755732.Fluta_1248	3.153e-42	163.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,1I17C@117743|Flavobacteriia,2PB4U@246874|Cryomorphaceae	976|Bacteroidetes	S	Uncharacterized ACR, COG1399	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
TLS3_k127_6194406_7	755732.Fluta_1247	3.764e-153	491.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,1HWZ8@117743|Flavobacteriia,2PAJ1@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Pyridoxal phosphate biosynthetic protein PdxA	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
TLS3_k127_6194406_5	755732.Fluta_1246	1.276e-159	515.0	COG0260@1|root,COG0260@2|Bacteria,4NDWT@976|Bacteroidetes,1HZZ2@117743|Flavobacteriia,2PA9B@246874|Cryomorphaceae	976|Bacteroidetes	E	Cytosol aminopeptidase family, catalytic domain	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
TLS3_k127_6194406_1	755732.Fluta_1237	0.0	1055.0	COG1032@1|root,COG1032@2|Bacteria,4NGYA@976|Bacteroidetes,1I02A@117743|Flavobacteriia,2PBIF@246874|Cryomorphaceae	976|Bacteroidetes	C	Domain of unknown function (DUF3362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
TLS3_k127_6194406_22	1237149.C900_03820	3.227e-18	89.0	COG0859@1|root,COG0859@2|Bacteria,4P2TG@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
TLS3_k127_6196722_0	755732.Fluta_1427	8.547e-267	850.0	COG0204@1|root,COG4106@1|root,COG4258@1|root,COG0204@2|Bacteria,COG4106@2|Bacteria,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,1HYZW@117743|Flavobacteriia,2PA97@246874|Cryomorphaceae	976|Bacteroidetes	I	O-methyltransferase	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
TLS3_k127_6208748_4	1443665.JACA01000034_gene2418	3.338e-14	76.0	2E3E6@1|root,32YD9@2|Bacteria,4NVFI@976|Bacteroidetes,1IHWC@117743|Flavobacteriia,2YK17@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6208748_1	1296416.JACB01000001_gene3172	1.672e-44	167.0	2E5Q2@1|root,330EP@2|Bacteria,4NUMS@976|Bacteroidetes,1I3WJ@117743|Flavobacteriia,2YJF1@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6208748_0	313603.FB2170_04755	5.326e-57	203.0	COG1595@1|root,COG1595@2|Bacteria,4NPC0@976|Bacteroidetes,1I2J7@117743|Flavobacteriia,2PHKD@252356|Maribacter	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_6208748_3	1313421.JHBV01000046_gene296	4.721e-30	135.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Peptidase_M28
TLS3_k127_6208748_2	1443665.JACA01000013_gene4224	2.198e-43	179.0	COG3064@1|root,COG3064@2|Bacteria,4P218@976|Bacteroidetes,1I87T@117743|Flavobacteriia,2YKU4@290174|Aquimarina	976|Bacteroidetes	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
TLS3_k127_6212305_5	411479.BACUNI_04298	7.844e-52	186.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,2FNQP@200643|Bacteroidia,4AT6W@815|Bacteroidaceae	976|Bacteroidetes	G	COG COG0381 UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.23	ko:K13019	ko00520,map00520	-	R09600	RC00290	ko00000,ko00001,ko01000,ko01005	-	-	-	Epimerase_2
TLS3_k127_6212305_0	755732.Fluta_2192	1.024e-114	379.0	COG1215@1|root,COG1215@2|Bacteria,4NT9I@976|Bacteroidetes,1ICDJ@117743|Flavobacteriia,2PB9X@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_6212305_8	521011.Mpal_0837	3.195e-25	113.0	COG1796@1|root,arCOG00305@2157|Archaea	2157|Archaea	L	DNA polymerase IV (family X)	-	-	-	ko:K02347,ko:K04477	-	-	-	-	ko00000,ko03400	-	-	-	PHP
TLS3_k127_6212305_3	521011.Mpal_0836	2.464e-88	303.0	COG3919@1|root,arCOG06897@2157|Archaea,2Y7IK@28890|Euryarchaeota,2NBB1@224756|Methanomicrobia	224756|Methanomicrobia	S	ATP-grasp domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	-
TLS3_k127_6212305_1	755732.Fluta_2190	8.143e-114	369.0	COG2120@1|root,COG2120@2|Bacteria,4NN16@976|Bacteroidetes	976|Bacteroidetes	S	PFAM N-acetylglucosaminyl phosphatidylinositol deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TLS3_k127_6212305_6	1408433.JHXV01000024_gene1491	5.428e-42	170.0	COG3307@1|root,COG3307@2|Bacteria,4NXNX@976|Bacteroidetes,1ICS9@117743|Flavobacteriia,2PBZ8@246874|Cryomorphaceae	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
TLS3_k127_6212305_4	1408433.JHXV01000024_gene1490	9.89e-77	269.0	COG0438@1|root,COG0438@2|Bacteria,4NU4C@976|Bacteroidetes,1I610@117743|Flavobacteriia,2PC3C@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase 4-like	remC	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
TLS3_k127_6212305_2	1408433.JHXV01000024_gene1489	3.355e-91	314.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,1HWNP@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_6212305_7	1408433.JHXV01000024_gene1488	6.933e-36	147.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Exostosin,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
TLS3_k127_6215486_1	755732.Fluta_2853	6.965e-294	931.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,4NDY1@976|Bacteroidetes,1HXDN@117743|Flavobacteriia,2PBBW@246874|Cryomorphaceae	976|Bacteroidetes	O	Cytochrome C assembly protein	ccmC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
TLS3_k127_6215486_0	755732.Fluta_1192	4.561e-316	993.0	COG2982@1|root,COG3064@1|root,COG2982@2|Bacteria,COG3064@2|Bacteria,4NEJQ@976|Bacteroidetes,1HXHN@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2
TLS3_k127_6215486_2	1346330.M472_19680	9.918e-179	580.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,1IP14@117747|Sphingobacteriia	976|Bacteroidetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
TLS3_k127_6215486_3	755732.Fluta_2414	7.402e-161	511.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,1HWM5@117743|Flavobacteriia,2PAIP@246874|Cryomorphaceae	976|Bacteroidetes	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
TLS3_k127_6215486_4	755732.Fluta_2413	4.848e-148	473.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,1HWPZ@117743|Flavobacteriia,2PAEY@246874|Cryomorphaceae	976|Bacteroidetes	T	PhoH-like protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
TLS3_k127_6232759_2	865938.Weevi_2006	2.402e-65	236.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1HXTJ@117743|Flavobacteriia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
TLS3_k127_6232759_1	755732.Fluta_0031	7.933e-113	371.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,1HWJN@117743|Flavobacteriia,2PATR@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
TLS3_k127_6232759_0	216432.CA2559_09453	1.556e-137	448.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1HWSS@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
TLS3_k127_6232759_3	755732.Fluta_0033	5.267e-39	147.0	2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,1I2X0@117743|Flavobacteriia,2PB4H@246874|Cryomorphaceae	976|Bacteroidetes	S	RNA polymerase Rpb6	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
TLS3_k127_6242780_4	349106.PsycPRwf_0229	7.283e-05	48.0	COG0451@1|root,COG2148@1|root,COG0451@2|Bacteria,COG2148@2|Bacteria,1MX2J@1224|Proteobacteria,1RPHW@1236|Gammaproteobacteria,3NM12@468|Moraxellaceae	1236|Gammaproteobacteria	M	NAD(P)H-binding	wbpV	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
TLS3_k127_6242780_0	1124780.ANNU01000038_gene199	3.25e-252	807.0	COG2192@1|root,COG2755@1|root,COG2192@2|Bacteria,COG2755@2|Bacteria,4NEV9@976|Bacteroidetes,47JR5@768503|Cytophagia	976|Bacteroidetes	O	PFAM Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
TLS3_k127_6242780_1	755732.Fluta_2915	1.367e-85	301.0	COG1520@1|root,COG1520@2|Bacteria,4PBXV@976|Bacteroidetes,1ICQN@117743|Flavobacteriia,2PBSC@246874|Cryomorphaceae	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6242780_3	1231190.NA8A_23132	1.634e-18	98.0	COG0438@1|root,COG0438@2|Bacteria,1PDZE@1224|Proteobacteria,2TR1N@28211|Alphaproteobacteria,43GW7@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4
TLS3_k127_6242780_2	1408433.JHXV01000037_gene2563	1.298e-26	120.0	COG1215@1|root,COG1215@2|Bacteria,4NIMF@976|Bacteroidetes,1I667@117743|Flavobacteriia,2PBTY@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_6243232_6	1408433.JHXV01000015_gene1802	5.197e-57	199.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,1I2TQ@117743|Flavobacteriia,2PB72@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
TLS3_k127_6243232_4	1408433.JHXV01000031_gene3249	7.168e-71	244.0	COG3832@1|root,COG3832@2|Bacteria,4NPKI@976|Bacteroidetes,1I28I@117743|Flavobacteriia,2PBRC@246874|Cryomorphaceae	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_6243232_5	929556.Solca_2015	4.693e-65	236.0	COG3239@1|root,COG3239@2|Bacteria,4NKXX@976|Bacteroidetes,1J080@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_6243232_8	69042.WH5701_09845	3.408e-39	152.0	COG0668@1|root,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
TLS3_k127_6243232_10	1349822.NSB1T_11350	5.77e-07	61.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_6243232_7	1537917.JU82_10225	1.198e-45	169.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,42TN9@68525|delta/epsilon subdivisions,2YPC4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
TLS3_k127_6243232_3	700598.Niako_2529	5.663e-85	286.0	COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,1IS56@117747|Sphingobacteriia	976|Bacteroidetes	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
TLS3_k127_6243232_1	1313421.JHBV01000012_gene4079	3.228e-108	362.0	COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,1ISE9@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
TLS3_k127_6243232_0	471854.Dfer_5803	1.119e-146	474.0	COG0304@1|root,COG0304@2|Bacteria,4NKN3@976|Bacteroidetes,47UCF@768503|Cytophagia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_6243232_9	755732.Fluta_1452	1.914e-37	142.0	COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes,1IMQ4@117743|Flavobacteriia,2PB31@246874|Cryomorphaceae	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TLS3_k127_6243232_2	755732.Fluta_1451	6.669e-89	298.0	COG0842@1|root,COG0842@2|Bacteria,4NGFA@976|Bacteroidetes,1HYPT@117743|Flavobacteriia,2PAFC@246874|Cryomorphaceae	976|Bacteroidetes	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
TLS3_k127_6254370_1	760192.Halhy_6240	5.359e-60	221.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_6254370_0	760192.Halhy_6239	1.898e-95	319.0	COG0745@1|root,COG0745@2|Bacteria,4NMAC@976|Bacteroidetes,1J08E@117747|Sphingobacteriia	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_6254370_2	616991.JPOO01000001_gene4614	1.363e-33	130.0	2AY99@1|root,31QBJ@2|Bacteria,4NNSA@976|Bacteroidetes,1I2AG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
TLS3_k127_6257057_0	1408433.JHXV01000009_gene1306	0.0	1125.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1HXPM@117743|Flavobacteriia,2PAHX@246874|Cryomorphaceae	976|Bacteroidetes	L	Bacterial DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
TLS3_k127_6257057_1	755732.Fluta_0948	1.374e-111	367.0	COG2912@1|root,COG2912@2|Bacteria,4NF8R@976|Bacteroidetes,1I9JB@117743|Flavobacteriia,2PBK9@246874|Cryomorphaceae	976|Bacteroidetes	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
TLS3_k127_6282826_4	1121904.ARBP01000046_gene1874	9.76e-13	71.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,47KKB@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
TLS3_k127_6282826_5	1041826.FCOL_05730	2.209e-08	60.0	2E46C@1|root,32Z2A@2|Bacteria,4NV81@976|Bacteroidetes,1I537@117743|Flavobacteriia,2NXAP@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6282826_2	269798.CHU_2731	5.181e-43	169.0	COG0642@1|root,COG0642@2|Bacteria,4NEW4@976|Bacteroidetes,47PC9@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_6282826_0	714943.Mucpa_7113	2.672e-77	265.0	COG0745@1|root,COG0745@2|Bacteria,4NGVV@976|Bacteroidetes,1IPYW@117747|Sphingobacteriia	976|Bacteroidetes	K	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_6282826_3	1408433.JHXV01000008_gene221	1.23e-21	109.0	COG1807@1|root,COG1807@2|Bacteria,4NXNF@976|Bacteroidetes,1IMQ5@117743|Flavobacteriia,2PB6F@246874|Cryomorphaceae	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6282826_1	443144.GM21_1658	2.857e-64	239.0	2DNVT@1|root,32ZDR@2|Bacteria,1QWIA@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6296993_7	755732.Fluta_3099	2.061e-49	178.0	COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,1I1YF@117743|Flavobacteriia,2PB2E@246874|Cryomorphaceae	976|Bacteroidetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
TLS3_k127_6296993_5	755732.Fluta_2781	2.838e-59	214.0	COG3757@1|root,COG3757@2|Bacteria,4NKHF@976|Bacteroidetes,1I18E@117743|Flavobacteriia,2PBSS@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl hydrolases family 25	acm	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25
TLS3_k127_6296993_1	755732.Fluta_3110	3.396e-273	856.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1HYK6@117743|Flavobacteriia,2PA4T@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
TLS3_k127_6296993_3	1121898.Q766_07995	5.01e-92	315.0	COG1090@1|root,COG1090@2|Bacteria,4NH8J@976|Bacteroidetes,1HXMJ@117743|Flavobacteriia,2NTRN@237|Flavobacterium	976|Bacteroidetes	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
TLS3_k127_6296993_6	755732.Fluta_0021	1.07e-56	208.0	COG3011@1|root,COG3011@2|Bacteria,4NN81@976|Bacteroidetes,1I1I4@117743|Flavobacteriia,2PC16@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
TLS3_k127_6296993_4	755732.Fluta_0020	3.564e-60	213.0	COG1510@1|root,COG1510@2|Bacteria,4NQPD@976|Bacteroidetes,1I39Q@117743|Flavobacteriia,2PB2G@246874|Cryomorphaceae	976|Bacteroidetes	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,MarR_2,TrmB
TLS3_k127_6296993_2	755732.Fluta_2506	2.518e-127	425.0	2DBNY@1|root,2ZA6F@2|Bacteria,4NH2P@976|Bacteroidetes,1I47S@117743|Flavobacteriia,2PAQ9@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6296993_0	1408433.JHXV01000038_gene2202	0.0	1240.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia,2PBJJ@246874|Cryomorphaceae	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
TLS3_k127_6323082_2	755732.Fluta_3594	2.657e-87	291.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,1HYNV@117743|Flavobacteriia,2PAKZ@246874|Cryomorphaceae	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
TLS3_k127_6323082_3	755732.Fluta_3592	4.727e-74	256.0	COG0566@1|root,COG0566@2|Bacteria,4NFH3@976|Bacteroidetes,1HX2E@117743|Flavobacteriia,2PBPZ@246874|Cryomorphaceae	976|Bacteroidetes	J	SpoU rRNA Methylase family	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
TLS3_k127_6323082_5	755732.Fluta_3589	2.048e-38	146.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,1I43K@117743|Flavobacteriia,2PB3N@246874|Cryomorphaceae	976|Bacteroidetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
TLS3_k127_6323082_1	880074.BARVI_04585	5.608e-93	315.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,2FN5I@200643|Bacteroidia,22VZZ@171551|Porphyromonadaceae	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
TLS3_k127_6323082_0	755732.Fluta_3587	8.359e-124	412.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1HX7D@117743|Flavobacteriia,2PB8H@246874|Cryomorphaceae	976|Bacteroidetes	V	efflux protein, MATE family	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
TLS3_k127_6323082_4	1408433.JHXV01000036_gene244	3e-68	233.0	COG1092@1|root,COG1092@2|Bacteria,4NG9S@976|Bacteroidetes,1HYAK@117743|Flavobacteriia,2PA9M@246874|Cryomorphaceae	976|Bacteroidetes	J	S-adenosylmethionine-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
TLS3_k127_632857_1	755732.Fluta_3579	8.862e-92	304.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1HY87@117743|Flavobacteriia,2PAET@246874|Cryomorphaceae	976|Bacteroidetes	EH	TIGRFAM branched-chain amino acid aminotransferase, group II	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_632857_2	755732.Fluta_3942	6.723e-90	301.0	COG2197@1|root,COG2197@2|Bacteria,4NNVV@976|Bacteroidetes,1ICPE@117743|Flavobacteriia,2PBHR@246874|Cryomorphaceae	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
TLS3_k127_632857_6	1122179.KB890447_gene173	3.579e-14	85.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase,VPEP
TLS3_k127_632857_3	755732.Fluta_3944	9.66e-83	279.0	COG1595@1|root,COG1595@2|Bacteria,4NT79@976|Bacteroidetes,1IIVT@117743|Flavobacteriia,2PBR9@246874|Cryomorphaceae	976|Bacteroidetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_632857_5	755732.Fluta_0129	7.397e-57	207.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,1HX2G@117743|Flavobacteriia,2PBU1@246874|Cryomorphaceae	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
TLS3_k127_632857_0	755732.Fluta_0128	3.541e-96	330.0	COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,1HYEB@117743|Flavobacteriia,2PBF8@246874|Cryomorphaceae	976|Bacteroidetes	H	Domain of unknown function (DUF4301)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4301
TLS3_k127_632857_4	755732.Fluta_0127	4.496e-58	206.0	COG1721@1|root,COG1721@2|Bacteria,4NG0C@976|Bacteroidetes,1HXKI@117743|Flavobacteriia,2PAFJ@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
TLS3_k127_6342041_0	755732.Fluta_2690	2.666e-155	492.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1HX21@117743|Flavobacteriia,2PAM0@246874|Cryomorphaceae	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
TLS3_k127_6342041_1	714943.Mucpa_0967	9.354e-09	59.0	COG2972@1|root,COG2972@2|Bacteria,4NN3P@976|Bacteroidetes,1IXG5@117747|Sphingobacteriia	976|Bacteroidetes	T	Signal transduction histidine kinase, LytS	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
TLS3_k127_6351754_3	755732.Fluta_1535	1.66e-183	576.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,1HWN4@117743|Flavobacteriia,2PAM7@246874|Cryomorphaceae	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
TLS3_k127_6351754_4	755732.Fluta_1536	3.699e-42	159.0	COG0319@1|root,COG0319@2|Bacteria,4NS93@976|Bacteroidetes,1I2W7@117743|Flavobacteriia,2PB4T@246874|Cryomorphaceae	976|Bacteroidetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	-	-	-	-	-	-	-	-	-	UPF0054
TLS3_k127_6351754_5	755732.Fluta_1537	1.103e-41	157.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,1ICR4@117743|Flavobacteriia,2PBUN@246874|Cryomorphaceae	976|Bacteroidetes	T	Histidine kinase-like ATPase domain	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
TLS3_k127_6351754_0	755732.Fluta_1538	3.066e-316	1002.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1HYD4@117743|Flavobacteriia,2PAG2@246874|Cryomorphaceae	976|Bacteroidetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
TLS3_k127_6351754_1	755732.Fluta_1539	2.619e-254	791.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1HXQH@117743|Flavobacteriia,2PAM6@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
TLS3_k127_6351754_6	755732.Fluta_1540	1.208e-40	153.0	COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,1I2V4@117743|Flavobacteriia,2PB44@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
TLS3_k127_6351754_7	880071.Fleli_1219	1.601e-38	164.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4PNPQ@976|Bacteroidetes,47YDQ@768503|Cytophagia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6351754_2	1313421.JHBV01000012_gene4088	1.645e-202	644.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl,Trp_halogenase
TLS3_k127_6356647_0	755732.Fluta_1475	1.626e-121	401.0	COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes,1HWV6@117743|Flavobacteriia,2PBBY@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
TLS3_k127_6356647_1	1123234.AUKI01000017_gene2596	5.592e-90	299.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,1HY8G@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
TLS3_k127_6365735_1	313606.M23134_02803	5.219e-36	138.0	COG3476@1|root,COG3476@2|Bacteria,4NP0D@976|Bacteroidetes,47T79@768503|Cytophagia	976|Bacteroidetes	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
TLS3_k127_6365735_0	755732.Fluta_2690	0.0	1463.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1HX21@117743|Flavobacteriia,2PAM0@246874|Cryomorphaceae	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
TLS3_k127_637862_0	1313421.JHBV01000021_gene4832	7.534e-116	375.0	COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,1IPQ0@117747|Sphingobacteriia	976|Bacteroidetes	O	AhpC TSA family	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
TLS3_k127_637862_2	1453505.JASY01000002_gene2969	2.743e-45	167.0	COG5646@1|root,COG5646@2|Bacteria,4NSVI@976|Bacteroidetes,1INEX@117743|Flavobacteriia,2NZDB@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
TLS3_k127_637862_3	1089547.KB913013_gene2172	6.451e-37	144.0	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,47QJ6@768503|Cytophagia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_7
TLS3_k127_637862_1	1453498.LG45_11590	1.016e-51	184.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,1HY4C@117743|Flavobacteriia,2NS9D@237|Flavobacterium	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
TLS3_k127_6381891_1	1117314.PCIT_04747	1.82e-97	323.0	COG3910@1|root,COG3910@2|Bacteria,1MZSY@1224|Proteobacteria,1RZF5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
TLS3_k127_6381891_0	641526.ADIWIN_3181	1.506e-121	399.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1HWMZ@117743|Flavobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
TLS3_k127_6384954_1	880071.Fleli_2088	2.031e-93	311.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,47KTH@768503|Cytophagia	976|Bacteroidetes	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
TLS3_k127_6384954_2	755732.Fluta_0181	1.901e-43	160.0	COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,1I2WI@117743|Flavobacteriia,2PAZN@246874|Cryomorphaceae	976|Bacteroidetes	L	bacterial (prokaryotic) histone like domain	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
TLS3_k127_6384954_4	714943.Mucpa_2551	6.361e-06	48.0	2EIUI@1|root,33CJV@2|Bacteria,4NYR6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6384954_0	755732.Fluta_0180	5.522e-266	825.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1HWJC@117743|Flavobacteriia,2PAHS@246874|Cryomorphaceae	976|Bacteroidetes	J	Ribonuclease E/G family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
TLS3_k127_6384954_3	1122225.AULQ01000005_gene2622	5.287e-35	139.0	COG2137@1|root,COG2137@2|Bacteria,4NSAS@976|Bacteroidetes,1I25J@117743|Flavobacteriia	976|Bacteroidetes	S	Regulatory protein RecX	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
TLS3_k127_6385790_2	755732.Fluta_3436	1.014e-117	385.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,1HXVJ@117743|Flavobacteriia,2PAR4@246874|Cryomorphaceae	976|Bacteroidetes	K	NusB family	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
TLS3_k127_6385790_10	755732.Fluta_3437	2.836e-28	118.0	2CG1Y@1|root,330K1@2|Bacteria,4NYMT@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
TLS3_k127_6385790_12	1408433.JHXV01000021_gene1677	1.27e-21	96.0	COG1862@1|root,COG1862@2|Bacteria,4NUT4@976|Bacteroidetes,1I3WA@117743|Flavobacteriia,2PB9B@246874|Cryomorphaceae	976|Bacteroidetes	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
TLS3_k127_6385790_9	1408433.JHXV01000012_gene3983	1.507e-30	129.0	2ABPU@1|root,3115Y@2|Bacteria,4PFWD@976|Bacteroidetes,1IGBE@117743|Flavobacteriia,2PC59@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4294
TLS3_k127_6385790_11	755732.Fluta_3401	2.264e-22	102.0	2AD3S@1|root,312S2@2|Bacteria,4PHQF@976|Bacteroidetes,1ICRJ@117743|Flavobacteriia,2PBWH@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6385790_5	1347369.CCAD010000078_gene2946	2.194e-71	248.0	COG4912@1|root,COG4912@2|Bacteria,1TSAW@1239|Firmicutes,4HM25@91061|Bacilli,1ZDKZ@1386|Bacillus	91061|Bacilli	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
TLS3_k127_6385790_6	1453500.AT05_05380	2.546e-62	228.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	4.2.2.1	ko:K01727	-	-	-	-	ko00000,ko01000	-	PL8	-	Alginate_lyase,BNR_2,Exo_endo_phos,F5_F8_type_C,Laminin_G_3,Metallophos,PA14,SASA,SLH
TLS3_k127_6385790_0	755732.Fluta_3403	5.036e-168	554.0	COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,1HXSM@117743|Flavobacteriia,2PAQV@246874|Cryomorphaceae	976|Bacteroidetes	P	TonB dependent receptor	phuR	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_6385790_13	1313421.JHBV01000031_gene1463	0.000169	53.0	COG1520@1|root,COG2132@1|root,COG1520@2|Bacteria,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	copA	-	1.16.3.3	ko:K17713,ko:K22348	-	-	-	-	ko00000,ko01000,ko02000	1.B.33.1	-	-	Cu-oxidase_2,Cu-oxidase_3
TLS3_k127_6385790_3	1168034.FH5T_16825	3.49e-102	338.0	COG1187@1|root,COG1187@2|Bacteria,4NFE1@976|Bacteroidetes,2FN5R@200643|Bacteroidia	976|Bacteroidetes	J	S4 RNA-binding domain	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS3_k127_6385790_4	391587.KAOT1_12992	9.427e-72	247.0	COG1670@1|root,COG1670@2|Bacteria,4NM3W@976|Bacteroidetes,1I1MN@117743|Flavobacteriia	976|Bacteroidetes	J	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TLS3_k127_6385790_1	1380600.AUYN01000009_gene1476	4.582e-140	452.0	COG3540@1|root,COG3540@2|Bacteria,4NDUS@976|Bacteroidetes,1HYTM@117743|Flavobacteriia	976|Bacteroidetes	P	COG3540 Phosphodiesterase alkaline phosphatase D	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
TLS3_k127_6385790_8	1121007.AUML01000006_gene3098	1.424e-49	186.0	COG1670@1|root,COG1670@2|Bacteria,4NSIH@976|Bacteroidetes,1I4PX@117743|Flavobacteriia,2YJD0@290174|Aquimarina	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
TLS3_k127_6385790_7	1121285.AUFK01000016_gene3517	3.289e-50	179.0	COG3759@1|root,COG3759@2|Bacteria,4NQA8@976|Bacteroidetes,1I2SZ@117743|Flavobacteriia,3ZRWU@59732|Chryseobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1304)	-	-	-	ko:K08987	-	-	-	-	ko00000	-	-	-	DUF1304
TLS3_k127_6424911_2	435591.BDI_3541	3.742e-10	70.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,2FQU9@200643|Bacteroidia,22W8U@171551|Porphyromonadaceae	976|Bacteroidetes	G	Domain of unknown function (DUF5110)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,F5_F8_type_C,Gal_mutarotas_2,Glyco_hydro_31,fn3
TLS3_k127_6424911_1	1122179.KB890428_gene2951	2.819e-74	258.0	COG4667@1|root,COG4667@2|Bacteria,4NIX2@976|Bacteroidetes	976|Bacteroidetes	S	Phospholipase, patatin family	rssA	-	-	-	-	-	-	-	-	-	-	-	Patatin
TLS3_k127_6424911_0	1408433.JHXV01000027_gene3728	3.142e-87	299.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
TLS3_k127_6424911_3	666509.RCA23_c03210	0.0003928	52.0	COG1956@1|root,COG4191@1|root,COG1956@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2U3W3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
TLS3_k127_643819_1	1408433.JHXV01000001_gene799	1.614e-59	221.0	COG2208@1|root,COG2208@2|Bacteria,4NKKK@976|Bacteroidetes,1I2H2@117743|Flavobacteriia,2PBG4@246874|Cryomorphaceae	976|Bacteroidetes	KT	7TMR-DISM extracellular 2	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,SpoIIE
TLS3_k127_643819_3	1123037.AUDE01000023_gene2766	3.694e-23	108.0	2E3AK@1|root,30JD7@2|Bacteria,4NPG4@976|Bacteroidetes,1I2KJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_643819_0	755732.Fluta_1004	4.179e-63	219.0	COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,1I202@117743|Flavobacteriia,2PAYJ@246874|Cryomorphaceae	976|Bacteroidetes	J	Ribosomal protein L9, C-terminal domain	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
TLS3_k127_643819_2	755732.Fluta_1003	8.462e-45	163.0	COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,1I2TD@117743|Flavobacteriia,2PB5Y@246874|Cryomorphaceae	976|Bacteroidetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
TLS3_k127_643819_4	1227266.HMPREF1551_00041	5.26e-11	64.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,1I21M@117743|Flavobacteriia,1ERY7@1016|Capnocytophaga	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
TLS3_k127_6441214_0	869213.JCM21142_336	1.014e-128	423.0	COG1073@1|root,COG1073@2|Bacteria,4PC2H@976|Bacteroidetes,47WQ8@768503|Cytophagia	976|Bacteroidetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6441214_2	1229487.AMYW01000008_gene1143	4.481e-13	74.0	COG5504@1|root,COG5504@2|Bacteria,4NJ10@976|Bacteroidetes,1HZGD@117743|Flavobacteriia,2NWUH@237|Flavobacterium	976|Bacteroidetes	O	Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF2268
TLS3_k127_6448969_2	755732.Fluta_2043	5.995e-95	314.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,1HXT0@117743|Flavobacteriia,2PAH1@246874|Cryomorphaceae	976|Bacteroidetes	S	Possible lysine decarboxylase	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
TLS3_k127_6448969_3	755732.Fluta_2073	4.84e-80	276.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,1HZYF@117743|Flavobacteriia,2PAX0@246874|Cryomorphaceae	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
TLS3_k127_6448969_5	1120966.AUBU01000002_gene2247	8.194e-25	120.0	COG0457@1|root,COG0457@2|Bacteria,4NGS0@976|Bacteroidetes,47MD8@768503|Cytophagia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_12,TPR_7,TPR_8
TLS3_k127_6448969_6	1458275.AZ34_16245	4.556e-09	69.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2VQTQ@28216|Betaproteobacteria,4AC2Q@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_6448969_4	1408433.JHXV01000024_gene1451	7.263e-77	264.0	COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,1I2CE@117743|Flavobacteriia,2PBPQ@246874|Cryomorphaceae	976|Bacteroidetes	GM	COG4464 Capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
TLS3_k127_6448969_1	1408433.JHXV01000024_gene1467	4.417e-169	537.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,1HX7N@117743|Flavobacteriia,2PAJ5@246874|Cryomorphaceae	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
TLS3_k127_6448969_0	755732.Fluta_2063	1.897e-235	732.0	COG0677@1|root,COG0677@2|Bacteria,4NDTW@976|Bacteroidetes,1HWYT@117743|Flavobacteriia,2PA8J@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM UDP-glucose GDP-mannose dehydrogenase family, NAD binding domain	wbpO	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TLS3_k127_6456166_1	755732.Fluta_2371	7.388e-146	465.0	COG0777@1|root,COG0777@2|Bacteria,4NFMH@976|Bacteroidetes,1HXQR@117743|Flavobacteriia,2PAKP@246874|Cryomorphaceae	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
TLS3_k127_6456166_0	1034807.FBFL15_0551	3.156e-187	589.0	COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,1HXRN@117743|Flavobacteriia,2NTDX@237|Flavobacterium	976|Bacteroidetes	G	Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
TLS3_k127_6474090_3	643867.Ftrac_2035	1.539e-31	124.0	COG3016@1|root,COG3016@2|Bacteria,4NEQ4@976|Bacteroidetes,47MCF@768503|Cytophagia	976|Bacteroidetes	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
TLS3_k127_6474090_1	755732.Fluta_1142	9.059e-57	209.0	COG4912@1|root,COG4912@2|Bacteria,4NMNG@976|Bacteroidetes,1I4VK@117743|Flavobacteriia	976|Bacteroidetes	L	DNA alkylation repair enzyme	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
TLS3_k127_6474090_2	1249975.JQLP01000001_gene3179	5.614e-45	173.0	COG0454@1|root,COG0456@2|Bacteria,4NPA8@976|Bacteroidetes,1I18M@117743|Flavobacteriia,2P6R1@244698|Gillisia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_6474090_0	755732.Fluta_1126	7.404e-90	297.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1HY5U@117743|Flavobacteriia,2PA66@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_6482606_1	755732.Fluta_1631	8.399e-135	444.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,1HWW3@117743|Flavobacteriia,2PAWC@246874|Cryomorphaceae	976|Bacteroidetes	D	Peptidase family M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_6482606_0	755732.Fluta_1727	9.51e-173	555.0	COG3307@1|root,COG3307@2|Bacteria,4NMYT@976|Bacteroidetes,1I79G@117743|Flavobacteriia,2PAI6@246874|Cryomorphaceae	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
TLS3_k127_6482606_2	755732.Fluta_1728	1.115e-119	392.0	COG3206@1|root,COG3206@2|Bacteria,4NWAG@976|Bacteroidetes,1I785@117743|Flavobacteriia,2PAYX@246874|Cryomorphaceae	976|Bacteroidetes	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
TLS3_k127_6520_14	755732.Fluta_0529	2.002e-33	130.0	COG0407@1|root,COG0407@2|Bacteria,4NEQ7@976|Bacteroidetes,1HY0P@117743|Flavobacteriia,2PAK7@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
TLS3_k127_6520_8	755732.Fluta_0528	2.329e-82	283.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,1HY4H@117743|Flavobacteriia,2PARZ@246874|Cryomorphaceae	976|Bacteroidetes	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
TLS3_k127_6520_12	755732.Fluta_4008	4.655e-46	173.0	COG0400@1|root,COG0400@2|Bacteria,4NHWT@976|Bacteroidetes,1HZK4@117743|Flavobacteriia,2PB1U@246874|Cryomorphaceae	976|Bacteroidetes	S	Serine hydrolase (FSH1)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,FSH1
TLS3_k127_6520_7	755732.Fluta_0515	1.348e-85	287.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,1IG54@117743|Flavobacteriia,2PBA5@246874|Cryomorphaceae	976|Bacteroidetes	M	outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
TLS3_k127_6520_0	755732.Fluta_0514	0.0	1045.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1HXMC@117743|Flavobacteriia,2PA6I@246874|Cryomorphaceae	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
TLS3_k127_6520_2	755732.Fluta_0513	1.911e-261	809.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1HY7D@117743|Flavobacteriia,2PA92@246874|Cryomorphaceae	976|Bacteroidetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
TLS3_k127_6520_1	755732.Fluta_0510	3.322e-275	872.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_6520_15	1094466.KQS_12615	2.102e-30	137.0	COG5295@1|root,COG5295@2|Bacteria,4NV9S@976|Bacteroidetes,1I8F6@117743|Flavobacteriia,2P0DN@237|Flavobacterium	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
TLS3_k127_6520_11	700598.Niako_4749	8.179e-48	190.0	COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1IVP5@117747|Sphingobacteriia	976|Bacteroidetes	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
TLS3_k127_6520_4	755732.Fluta_0510	6.917e-184	602.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_6520_6	755732.Fluta_2695	1.652e-102	338.0	2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,1HY5Y@117743|Flavobacteriia,2PBHM@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
TLS3_k127_6520_5	755732.Fluta_2694	1.685e-118	387.0	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,1HYDH@117743|Flavobacteriia,2PAWF@246874|Cryomorphaceae	976|Bacteroidetes	F	Phosphorylase superfamily	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
TLS3_k127_6520_10	755732.Fluta_1327	1.824e-49	184.0	COG3142@1|root,COG3142@2|Bacteria,4NINY@976|Bacteroidetes,1I1FE@117743|Flavobacteriia,2PBUV@246874|Cryomorphaceae	976|Bacteroidetes	P	CutC family	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
TLS3_k127_6520_3	755732.Fluta_1326	1.608e-192	627.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1HXU1@117743|Flavobacteriia,2PBAW@246874|Cryomorphaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 20, domain 2	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
TLS3_k127_6520_19	1107311.Q767_15100	1.988e-11	70.0	2EGII@1|root,33AAP@2|Bacteria,4NXMZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6520_9	714943.Mucpa_0966	3.676e-53	193.0	COG3279@1|root,COG3279@2|Bacteria,4NHZR@976|Bacteroidetes,1IWRC@117747|Sphingobacteriia	976|Bacteroidetes	K	Two component transcriptional regulator, LytTR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_6558712_0	755732.Fluta_2092	1.215e-77	275.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1I0R3@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
TLS3_k127_6558712_2	574087.Acear_0862	2.386e-45	177.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,3WB4I@53433|Halanaerobiales	186801|Clostridia	P	TIGRFAM phosphate binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
TLS3_k127_6558712_1	755732.Fluta_2735	1.845e-54	201.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_6568709_1	1408433.JHXV01000001_gene799	5.799e-79	274.0	COG2208@1|root,COG2208@2|Bacteria,4NKKK@976|Bacteroidetes,1I2H2@117743|Flavobacteriia,2PBG4@246874|Cryomorphaceae	976|Bacteroidetes	KT	7TMR-DISM extracellular 2	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,SpoIIE
TLS3_k127_6568709_4	755732.Fluta_2517	4.2e-50	192.0	COG0614@1|root,COG0614@2|Bacteria,4NH9F@976|Bacteroidetes,1HWUZ@117743|Flavobacteriia,2PBWU@246874|Cryomorphaceae	976|Bacteroidetes	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
TLS3_k127_6568709_2	755732.Fluta_2518	1.833e-68	244.0	COG0609@1|root,COG0609@2|Bacteria,4NEDU@976|Bacteroidetes,1HXH4@117743|Flavobacteriia,2PBRH@246874|Cryomorphaceae	976|Bacteroidetes	P	FecCD transport family	hmuU	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
TLS3_k127_6568709_5	1122975.AQVC01000040_gene128	1.066e-43	169.0	COG1120@1|root,COG1120@2|Bacteria,4NG1Q@976|Bacteroidetes,2FMCI@200643|Bacteroidia,22XCS@171551|Porphyromonadaceae	976|Bacteroidetes	HP	COGs COG1120 ABC-type cobalamin Fe3 -siderophores transport systems ATPase components	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
TLS3_k127_6568709_0	616991.JPOO01000003_gene1687	5.907e-114	379.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,1HXGQ@117743|Flavobacteriia,23GGQ@178469|Arenibacter	976|Bacteroidetes	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
TLS3_k127_6568709_6	398767.Glov_0909	2.454e-27	123.0	COG0746@1|root,COG0746@2|Bacteria,1Q4P1@1224|Proteobacteria,42VEC@68525|delta/epsilon subdivisions,2WRVN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
TLS3_k127_6568709_7	504487.JCM19302_1721	3.242e-05	49.0	2DS5M@1|root,33END@2|Bacteria	2|Bacteria	S	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
TLS3_k127_6568709_3	620914.JH621250_gene2256	8.797e-60	209.0	COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,1I24D@117743|Flavobacteriia,2YHDT@290174|Aquimarina	976|Bacteroidetes	H	MoaE protein	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
TLS3_k127_658421_5	1380394.JADL01000011_gene4086	9.616e-08	64.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,2JPRT@204441|Rhodospirillales	204441|Rhodospirillales	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_10,TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_7,TPR_8
TLS3_k127_658421_6	1296416.JACB01000005_gene90	6.029e-05	54.0	COG1470@1|root,COG3227@1|root,COG4733@1|root,COG1470@2|Bacteria,COG3227@2|Bacteria,COG4733@2|Bacteria,4PKY7@976|Bacteroidetes,1IJH4@117743|Flavobacteriia	976|Bacteroidetes	E	Secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	MAM,Reprolysin_4,fn3
TLS3_k127_658421_1	755732.Fluta_3931	4.112e-217	677.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1HY78@117743|Flavobacteriia,2PAA3@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_658421_3	755732.Fluta_3930	5.221e-68	240.0	COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes,1IC3U@117743|Flavobacteriia,2PBQN@246874|Cryomorphaceae	976|Bacteroidetes	M	D-ala-D-ala dipeptidase	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
TLS3_k127_658421_0	266748.HY04_02310	1.262e-296	928.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1HX6P@117743|Flavobacteriia,3ZPJ2@59732|Chryseobacterium	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_658421_2	269798.CHU_1365	1.168e-75	260.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,47UCG@768503|Cytophagia	976|Bacteroidetes	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
TLS3_k127_658421_4	1086011.HJ01_00699	3.889e-19	88.0	COG0454@1|root,COG0456@2|Bacteria,4NQ3C@976|Bacteroidetes,1IIEU@117743|Flavobacteriia,2P0D2@237|Flavobacterium	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_6591333_5	755732.Fluta_1342	2.305e-132	424.0	COG1788@1|root,COG1788@2|Bacteria,4NF3T@976|Bacteroidetes,1HY5F@117743|Flavobacteriia,2PAM2@246874|Cryomorphaceae	976|Bacteroidetes	I	Coenzyme A transferase	scoA	-	2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01031,ko:K01034	ko00072,ko00280,ko00310,ko00362,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00362,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R02990,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
TLS3_k127_6591333_0	755732.Fluta_1343	5.673e-302	948.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HXWX@117743|Flavobacteriia,2PAGV@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Penicillin binding protein transpeptidase domain	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
TLS3_k127_6591333_4	755732.Fluta_1889	7.797e-194	614.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,1HXI4@117743|Flavobacteriia,2PAKS@246874|Cryomorphaceae	976|Bacteroidetes	D	Cell cycle protein	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
TLS3_k127_6591333_1	755732.Fluta_1888	9.346e-287	891.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1HX5G@117743|Flavobacteriia,2PA5A@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Penicillin binding protein transpeptidase domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
TLS3_k127_6591333_7	755732.Fluta_1887	6.576e-50	183.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,1I35P@117743|Flavobacteriia,2PB3Z@246874|Cryomorphaceae	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6591333_6	755732.Fluta_1886	2.571e-81	279.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,1HWJM@117743|Flavobacteriia,2PAZF@246874|Cryomorphaceae	976|Bacteroidetes	M	rod shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
TLS3_k127_6591333_3	755732.Fluta_1895	2.789e-196	614.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,1HXDD@117743|Flavobacteriia,2PACA@246874|Cryomorphaceae	976|Bacteroidetes	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
TLS3_k127_6591333_2	1408433.JHXV01000006_gene2636	2.618e-245	765.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,1HXDR@117743|Flavobacteriia,2PA65@246874|Cryomorphaceae	976|Bacteroidetes	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
TLS3_k127_6592364_0	755732.Fluta_1066	0.0	1017.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,1HXTQ@117743|Flavobacteriia,2PB5K@246874|Cryomorphaceae	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_6592364_1	755732.Fluta_1126	1.131e-127	410.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1HY5U@117743|Flavobacteriia,2PA66@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_6600643_10	1048983.EL17_08195	2.62e-11	71.0	2DSJJ@1|root,33GER@2|Bacteria,4NZAF@976|Bacteroidetes,47UN4@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6600643_2	755732.Fluta_2512	5.782e-207	662.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,1HWJS@117743|Flavobacteriia,2PAJ3@246874|Cryomorphaceae	976|Bacteroidetes	OU	TIGRFAM signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
TLS3_k127_6600643_1	755732.Fluta_0186	7.67e-270	852.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,4PFHG@976|Bacteroidetes,1IG76@117743|Flavobacteriia,2PBAN@246874|Cryomorphaceae	976|Bacteroidetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14,Peptidase_M6
TLS3_k127_6600643_3	755732.Fluta_0358	7.806e-190	608.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,1HXJR@117743|Flavobacteriia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	pafA	GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519	-	-	-	-	-	-	-	-	-	-	Phosphodiest
TLS3_k127_6600643_9	1120966.AUBU01000002_gene1979	1.332e-56	214.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,47M2U@768503|Cytophagia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
TLS3_k127_6600643_6	1454007.JAUG01000087_gene3912	1.531e-104	352.0	COG0147@1|root,COG0147@2|Bacteria,4NECR@976|Bacteroidetes,1IPYM@117747|Sphingobacteriia	976|Bacteroidetes	EH	PFAM chorismate binding	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
TLS3_k127_6600643_4	1406840.Q763_11555	3.276e-188	599.0	COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,1HYPG@117743|Flavobacteriia,2NTH4@237|Flavobacterium	976|Bacteroidetes	MU	RND transporter	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_6600643_0	929562.Emtol_3782	0.0	1742.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47M4G@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
TLS3_k127_6600643_5	761193.Runsl_1792	4.347e-150	482.0	COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,47J8Y@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
TLS3_k127_6600643_7	755732.Fluta_0409	1.971e-99	340.0	COG0204@1|root,COG0204@2|Bacteria,4NN7X@976|Bacteroidetes,1HZQ9@117743|Flavobacteriia,2PBWD@246874|Cryomorphaceae	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TLS3_k127_6600643_8	869213.JCM21142_72609	1.743e-78	278.0	COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,47RSG@768503|Cytophagia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
TLS3_k127_6600643_11	1237149.C900_00018	6.763e-05	47.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47NPA@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS3_k127_6609855_6	1408433.JHXV01000019_gene1916	3.199e-56	202.0	COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,1IKD0@117743|Flavobacteriia,2PAFR@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_6609855_3	755732.Fluta_0302	2.872e-100	345.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	2.7.11.1	ko:K03570,ko:K11904,ko:K12132,ko:K21471	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01002,ko01011,ko02044,ko03036	3.A.23.1,9.B.157.1	-	-	LysM,SLT
TLS3_k127_6609855_0	1408433.JHXV01000001_gene915	6.81e-237	737.0	COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,1HWV9@117743|Flavobacteriia,2PBJV@246874|Cryomorphaceae	976|Bacteroidetes	C	Oxidoreductase NAD-binding domain	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
TLS3_k127_6609855_2	926562.Oweho_3405	4.618e-101	333.0	COG2209@1|root,COG2209@2|Bacteria,4NEU0@976|Bacteroidetes,1HX59@117743|Flavobacteriia,2PBFJ@246874|Cryomorphaceae	976|Bacteroidetes	C	Rnf-Nqr subunit, membrane protein	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
TLS3_k127_6609855_4	1296416.JACB01000015_gene4611	2.171e-90	302.0	COG1347@1|root,COG1347@2|Bacteria,4NGD9@976|Bacteroidetes,1HXGP@117743|Flavobacteriia,2YI3M@290174|Aquimarina	976|Bacteroidetes	C	Rnf-Nqr subunit, membrane protein	nqrD	-	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
TLS3_k127_6609855_5	1408433.JHXV01000001_gene918	4.072e-67	236.0	COG2869@1|root,COG2869@2|Bacteria,4NF7A@976|Bacteroidetes,1HZG0@117743|Flavobacteriia,2PBRW@246874|Cryomorphaceae	976|Bacteroidetes	C	FMN_bind	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
TLS3_k127_6609855_1	1408433.JHXV01000001_gene919	5.768e-159	510.0	COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,1HXYV@117743|Flavobacteriia,2PBHA@246874|Cryomorphaceae	976|Bacteroidetes	C	NQR2, RnfD, RnfE family	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
TLS3_k127_6609855_7	1408433.JHXV01000001_gene920	4.422e-39	147.0	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,1HWV3@117743|Flavobacteriia,2PBAX@246874|Cryomorphaceae	976|Bacteroidetes	C	Na(+)-translocating NADH-quinone reductase subunit A (NQRA)	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
TLS3_k127_6637894_2	1408433.JHXV01000009_gene1251	7.37e-99	342.0	COG0642@1|root,COG2205@2|Bacteria,4NFEF@976|Bacteroidetes,1HXAX@117743|Flavobacteriia,2PBD9@246874|Cryomorphaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
TLS3_k127_6637894_4	1121957.ATVL01000008_gene4338	8.729e-05	50.0	COG0745@1|root,COG0745@2|Bacteria,4NGVV@976|Bacteroidetes,47JTK@768503|Cytophagia	976|Bacteroidetes	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_6637894_0	929562.Emtol_0674	1.934e-177	588.0	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,47PGJ@768503|Cytophagia	976|Bacteroidetes	G	Participates in initiation and elongation during chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
TLS3_k127_6637894_1	755732.Fluta_2306	6.077e-126	412.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,1HXVZ@117743|Flavobacteriia,2PA7P@246874|Cryomorphaceae	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
TLS3_k127_6637894_3	755732.Fluta_2307	1.252e-11	64.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia,2PABJ@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Response regulator receiver domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_6661048_1	755732.Fluta_1180	7.881e-78	268.0	COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,1IG0F@117743|Flavobacteriia,2PB3U@246874|Cryomorphaceae	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
TLS3_k127_6661048_0	755732.Fluta_1179	1.804e-176	560.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,1HY1X@117743|Flavobacteriia,2PAAV@246874|Cryomorphaceae	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6661048_2	755732.Fluta_1178	2.13e-51	185.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,1HWR6@117743|Flavobacteriia,2PATF@246874|Cryomorphaceae	976|Bacteroidetes	C	Cytochrome C oxidase subunit II, transmembrane domain	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
TLS3_k127_6663347_1	755732.Fluta_3396	2.266e-119	391.0	COG3637@1|root,COG3637@2|Bacteria,4PJ16@976|Bacteroidetes,1ICQ3@117743|Flavobacteriia,2PBMQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6663347_0	1121899.Q764_12540	7.507e-145	467.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1HY59@117743|Flavobacteriia,2NSRJ@237|Flavobacterium	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
TLS3_k127_6663347_2	1121007.AUML01000008_gene980	9.098e-37	141.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,1HWWP@117743|Flavobacteriia,2YHX6@290174|Aquimarina	976|Bacteroidetes	E	HMGL-like	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
TLS3_k127_6664942_7	886379.AEWI01000020_gene1326	6.207e-07	59.0	2ACWQ@1|root,312I4@2|Bacteria,4PHHG@976|Bacteroidetes,2G1D2@200643|Bacteroidia,3XKVC@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6664942_2	926562.Oweho_2595	1.142e-36	145.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I1A4@117743|Flavobacteriia,2PBNV@246874|Cryomorphaceae	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	OMP_b-brl_2,Sigma70_r2,Sigma70_r4_2
TLS3_k127_6664942_4	1124780.ANNU01000071_gene1033	2.746e-11	76.0	2F9VV@1|root,3425D@2|Bacteria,4P498@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6664942_5	319236.JCM19294_1573	9.315e-10	62.0	2DBYA@1|root,2ZBU9@2|Bacteria,4NNGM@976|Bacteroidetes,1I19X@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6664942_0	1121930.AQXG01000008_gene147	1.356e-105	349.0	COG1230@1|root,COG1230@2|Bacteria,4NIHB@976|Bacteroidetes,1IXEH@117747|Sphingobacteriia	976|Bacteroidetes	P	Cation efflux family	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
TLS3_k127_6664942_1	313595.P700755_004026	3.35e-39	150.0	COG0642@1|root,COG1956@1|root,COG3829@1|root,COG1956@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,4NG0Y@976|Bacteroidetes,1HXCZ@117743|Flavobacteriia,4C348@83612|Psychroflexus	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3
TLS3_k127_6681250_0	755732.Fluta_0212	7.09e-113	384.0	COG2244@1|root,COG2244@2|Bacteria,4NEVQ@976|Bacteroidetes,1HYFW@117743|Flavobacteriia,2PAXG@246874|Cryomorphaceae	976|Bacteroidetes	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
TLS3_k127_6681250_3	755732.Fluta_3648	7.076e-26	113.0	COG2885@1|root,COG2885@2|Bacteria,4NP5H@976|Bacteroidetes,1I23F@117743|Flavobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
TLS3_k127_6681250_1	755732.Fluta_3647	7.556e-111	365.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,1HXSR@117743|Flavobacteriia,2PAMK@246874|Cryomorphaceae	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
TLS3_k127_6685810_1	745718.JADT01000012_gene988	2.121e-36	142.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,4PKKU@976|Bacteroidetes,1IJC1@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III, epsilon subunit	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
TLS3_k127_6685810_0	313606.M23134_06670	3.789e-69	259.0	COG2114@1|root,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,47MR3@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_12,TPR_8
TLS3_k127_6697532_4	1541065.JRFE01000003_gene5474	5.171e-40	156.0	COG0596@1|root,COG0596@2|Bacteria,1G5CD@1117|Cyanobacteria,3VMGK@52604|Pleurocapsales	1117|Cyanobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
TLS3_k127_6697532_6	926554.KI912671_gene249	9.766e-12	72.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TLS3_k127_6697532_3	755732.Fluta_3123	3.259e-57	208.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,1HXIX@117743|Flavobacteriia,2PB4B@246874|Cryomorphaceae	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
TLS3_k127_6697532_5	755732.Fluta_3124	1.142e-15	85.0	COG5456@1|root,COG5456@2|Bacteria,4P9QF@976|Bacteroidetes,1ICNH@117743|Flavobacteriia,2PBA3@246874|Cryomorphaceae	976|Bacteroidetes	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH
TLS3_k127_6697532_1	755732.Fluta_3125	1.387e-196	622.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1HXAK@117743|Flavobacteriia,2PAH8@246874|Cryomorphaceae	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase accessory protein FixG	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
TLS3_k127_6697532_2	755732.Fluta_3126	3.717e-118	399.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1HZ3Y@117743|Flavobacteriia,2PAXX@246874|Cryomorphaceae	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit III	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
TLS3_k127_6697532_7	1392488.JHZY01000004_gene2585	1.501e-07	64.0	2E7S7@1|root,3327D@2|Bacteria,4NUQB@976|Bacteroidetes,1I51Y@117743|Flavobacteriia,2XKD2@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Cbb3-type cytochrome oxidase component FixQ	ccoQ	-	-	-	-	-	-	-	-	-	-	-	FixQ
TLS3_k127_6697532_0	755732.Fluta_3128	1.044e-229	719.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1HWQ5@117743|Flavobacteriia,2PAJX@246874|Cryomorphaceae	976|Bacteroidetes	C	Cytochrome C and Quinol oxidase polypeptide I	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
TLS3_k127_6708056_3	755732.Fluta_1429	1.971e-37	142.0	COG0500@1|root,COG2226@2|Bacteria,4NGN8@976|Bacteroidetes,1IK35@117743|Flavobacteriia,2PAH3@246874|Cryomorphaceae	976|Bacteroidetes	H	O-methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
TLS3_k127_6708056_0	755732.Fluta_1430	4.385e-227	713.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1HX2V@117743|Flavobacteriia,2PABS@246874|Cryomorphaceae	976|Bacteroidetes	E	Aromatic amino acid lyase	hutH	-	4.3.1.23,4.3.1.3	ko:K01745,ko:K10774	ko00340,ko00350,ko01100,map00340,map00350,map01100	M00045	R00737,R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
TLS3_k127_6708056_2	755732.Fluta_1431	6.342e-108	355.0	COG1028@1|root,COG1028@2|Bacteria,4NFTU@976|Bacteroidetes,1HX2B@117743|Flavobacteriia,2PA8Q@246874|Cryomorphaceae	976|Bacteroidetes	IQ	KR domain	fabG3	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_6708056_1	755732.Fluta_1432	1.656e-205	644.0	COG0304@1|root,COG0304@2|Bacteria,4NFBN@976|Bacteroidetes,1HXQ3@117743|Flavobacteriia,2PAHI@246874|Cryomorphaceae	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabB	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_6708056_4	755732.Fluta_1433	2.005e-29	119.0	COG0236@1|root,COG0236@2|Bacteria,4NV57@976|Bacteroidetes,1I568@117743|Flavobacteriia,2PB5Z@246874|Cryomorphaceae	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	acpP_2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TLS3_k127_6708056_5	755732.Fluta_1434	1.024e-09	60.0	COG4261@1|root,COG4261@2|Bacteria,4NF49@976|Bacteroidetes,1HXDQ@117743|Flavobacteriia,2PAQR@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
TLS3_k127_6711152_3	935565.JAEM01000026_gene180	1.058e-10	63.0	COG4974@1|root,COG4974@2|Bacteria,1MXZX@1224|Proteobacteria,2U0B6@28211|Alphaproteobacteria,2PXDB@265|Paracoccus	28211|Alphaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
TLS3_k127_6711152_2	1178825.ALIH01000002_gene896	6.581e-22	100.0	COG0661@1|root,COG0661@2|Bacteria,4NDUP@976|Bacteroidetes,1HWK0@117743|Flavobacteriia	976|Bacteroidetes	S	unusual protein kinase	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
TLS3_k127_6711152_0	755732.Fluta_3206	2.94e-111	372.0	COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,1HXZJ@117743|Flavobacteriia,2PBDV@246874|Cryomorphaceae	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
TLS3_k127_6711152_1	1338011.BD94_0492	1.084e-108	370.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IJ7V@117743|Flavobacteriia,34S38@308865|Elizabethkingia	976|Bacteroidetes	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
TLS3_k127_6717921_6	7739.XP_002589371.1	8.755e-09	60.0	COG4886@1|root,KOG0619@2759|Eukaryota	7739.XP_002589371.1|-	U	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6717921_7	1121097.JCM15093_1644	2.02e-07	61.0	2EGII@1|root,33AAP@2|Bacteria,4NXMZ@976|Bacteroidetes,2FTW7@200643|Bacteroidia,4ARS6@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4890)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4890
TLS3_k127_6717921_3	755732.Fluta_2932	4.709e-76	258.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,1HX5F@117743|Flavobacteriia,2PC67@246874|Cryomorphaceae	976|Bacteroidetes	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
TLS3_k127_6717921_4	929562.Emtol_3687	1.679e-59	210.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,47PPC@768503|Cytophagia	976|Bacteroidetes	O	Conserved domain frequently associated with peptide methionine sulfoxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
TLS3_k127_6717921_0	755732.Fluta_2931	2.47e-107	360.0	COG0477@1|root,COG2814@2|Bacteria,4NE7F@976|Bacteroidetes,1HZ5N@117743|Flavobacteriia,2PBGG@246874|Cryomorphaceae	976|Bacteroidetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_6717921_2	1408433.JHXV01000004_gene3394	2.39e-78	269.0	COG1738@1|root,COG1738@2|Bacteria,4NFP3@976|Bacteroidetes,1HYC6@117743|Flavobacteriia,2PB3P@246874|Cryomorphaceae	976|Bacteroidetes	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
TLS3_k127_6717921_5	755732.Fluta_2929	1.32e-31	128.0	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,1I2UP@117743|Flavobacteriia,2PB5G@246874|Cryomorphaceae	976|Bacteroidetes	K	helix_turn_helix, mercury resistance	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
TLS3_k127_6717921_1	1121898.Q766_01220	1.435e-80	276.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,1HXKN@117743|Flavobacteriia,2NS7W@237|Flavobacterium	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
TLS3_k127_6748760_2	755732.Fluta_0695	1.295e-131	430.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4P0PU@976|Bacteroidetes,1IMQT@117743|Flavobacteriia,2PBGH@246874|Cryomorphaceae	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6748760_9	485918.Cpin_6900	4.472e-38	155.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IQ3Y@117747|Sphingobacteriia	976|Bacteroidetes	I	protein CHP03519, membrane, Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_6748760_10	755732.Fluta_1144	2.822e-14	74.0	2ACM1@1|root,3127F@2|Bacteria,4PH2W@976|Bacteroidetes,1ICTY@117743|Flavobacteriia,2PC5T@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6748760_6	755732.Fluta_1143	7.125e-62	218.0	COG1595@1|root,COG1595@2|Bacteria,4NU5Z@976|Bacteroidetes,1ICR3@117743|Flavobacteriia,2PBUG@246874|Cryomorphaceae	976|Bacteroidetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
TLS3_k127_6748760_5	755732.Fluta_2392	4.182e-67	235.0	COG0300@1|root,COG0300@2|Bacteria,4NEFB@976|Bacteroidetes,1HX0Q@117743|Flavobacteriia,2PAVS@246874|Cryomorphaceae	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_6748760_4	755732.Fluta_2393	1.389e-91	312.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1HX5B@117743|Flavobacteriia,2PA8I@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	dmpP	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
TLS3_k127_6748760_1	755732.Fluta_2394	1.941e-136	442.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1HX5B@117743|Flavobacteriia,2PA8I@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
TLS3_k127_6748760_0	755732.Fluta_2404	3.279e-172	544.0	COG3396@1|root,COG3396@2|Bacteria,4NFJN@976|Bacteroidetes,1HXY6@117743|Flavobacteriia,2PAG1@246874|Cryomorphaceae	976|Bacteroidetes	S	Phenylacetic acid catabolic protein	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
TLS3_k127_6748760_8	755732.Fluta_2403	1.482e-44	162.0	COG3460@1|root,COG3460@2|Bacteria,4NQFV@976|Bacteroidetes,1I2UD@117743|Flavobacteriia,2PB3H@246874|Cryomorphaceae	976|Bacteroidetes	Q	Phenylacetic acid degradation B	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
TLS3_k127_6748760_3	755732.Fluta_2402	2.592e-99	330.0	COG3396@1|root,COG3396@2|Bacteria,4NFIT@976|Bacteroidetes,1I05P@117743|Flavobacteriia,2PAWE@246874|Cryomorphaceae	976|Bacteroidetes	S	Phenylacetic acid catabolic protein	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
TLS3_k127_6748760_7	926562.Oweho_2261	2.175e-57	204.0	COG2151@1|root,COG3677@1|root,COG2151@2|Bacteria,COG3677@2|Bacteria,4NMS0@976|Bacteroidetes,1HXIB@117743|Flavobacteriia,2PB0A@246874|Cryomorphaceae	976|Bacteroidetes	L	Pfam:DUF59	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
TLS3_k127_6748760_12	1121895.Q765_06230	0.0006382	49.0	COG4969@1|root,COG4969@2|Bacteria,4NVUE@976|Bacteroidetes,1I5FG@117743|Flavobacteriia,2NXA9@237|Flavobacterium	976|Bacteroidetes	NU	Belongs to the N-Me-Phe pilin family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6748760_11	1408473.JHXO01000003_gene2584	5.569e-12	68.0	2E676@1|root,330VQ@2|Bacteria,4PA7N@976|Bacteroidetes,2FZJU@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_675739_2	755732.Fluta_3398	1.36e-63	222.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,1HWWP@117743|Flavobacteriia,2PA7K@246874|Cryomorphaceae	976|Bacteroidetes	E	HMGL-like	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
TLS3_k127_675739_5	755732.Fluta_3399	3.997e-30	127.0	2A3W6@1|root,30SEE@2|Bacteria,4PEHU@976|Bacteroidetes,1ICTA@117743|Flavobacteriia,2PC37@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_675739_3	755732.Fluta_3464	5.264e-56	205.0	2DPMN@1|root,332P9@2|Bacteria,4NPMQ@976|Bacteroidetes,1I2HP@117743|Flavobacteriia,2PBW7@246874|Cryomorphaceae	976|Bacteroidetes	S	Cleaved Adhesin Domain	-	-	-	-	-	-	-	-	-	-	-	-	Cleaved_Adhesin
TLS3_k127_675739_4	755732.Fluta_3465	1.616e-49	180.0	2AFX4@1|root,3160I@2|Bacteria,4PK9X@976|Bacteroidetes,1ICT9@117743|Flavobacteriia,2PC36@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
TLS3_k127_675739_6	1408433.JHXV01000023_gene3297	8.741e-28	117.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,1I51Q@117743|Flavobacteriia,2PC0A@246874|Cryomorphaceae	976|Bacteroidetes	COP	COGs COG0607 Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Thioredoxin
TLS3_k127_675739_1	1408433.JHXV01000023_gene3302	1.425e-92	326.0	COG3291@1|root,COG3291@2|Bacteria,4PBW3@976|Bacteroidetes,1ICPP@117743|Flavobacteriia,2PBJ2@246874|Cryomorphaceae	976|Bacteroidetes	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA
TLS3_k127_675739_0	926562.Oweho_1887	3.411e-117	392.0	COG2124@1|root,COG2124@2|Bacteria,4NG9Z@976|Bacteroidetes,1HY9E@117743|Flavobacteriia,2PBEC@246874|Cryomorphaceae	976|Bacteroidetes	C	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_1,Flavodoxin_1,NAD_binding_1,p450
TLS3_k127_675739_7	1121935.AQXX01000071_gene5037	4.433e-06	51.0	COG3146@1|root,COG3146@2|Bacteria,1QKPJ@1224|Proteobacteria,1SDWU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
TLS3_k127_6792442_1	755732.Fluta_3613	1.902e-97	325.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,1IMQS@117743|Flavobacteriia,2PBFS@246874|Cryomorphaceae	976|Bacteroidetes	CO	Domain of unknown function (DUF5106)	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
TLS3_k127_6792442_0	755732.Fluta_0380	3.321e-211	665.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1HYBR@117743|Flavobacteriia,2PAP0@246874|Cryomorphaceae	976|Bacteroidetes	E	peptidase M1	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
TLS3_k127_6797431_0	1492737.FEM08_32040	1.769e-184	586.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1HYZ9@117743|Flavobacteriia,2NT0S@237|Flavobacterium	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S
TLS3_k127_6797431_1	1317122.ATO12_01120	2.564e-104	345.0	COG1526@1|root,COG1526@2|Bacteria,4NFJB@976|Bacteroidetes,1I19N@117743|Flavobacteriia,2YI2A@290174|Aquimarina	976|Bacteroidetes	C	FdhD/NarQ family	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
TLS3_k127_6797431_2	886377.Murru_1145	1.028e-27	118.0	COG2318@1|root,COG2318@2|Bacteria,4NQ7Y@976|Bacteroidetes,1I386@117743|Flavobacteriia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
TLS3_k127_6799330_7	1296416.JACB01000001_gene3321	1.25e-08	61.0	2DBBT@1|root,2Z8AC@2|Bacteria,4NIRZ@976|Bacteroidetes,1HZMZ@117743|Flavobacteriia,2YKZ3@290174|Aquimarina	976|Bacteroidetes	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
TLS3_k127_6799330_3	1453500.AT05_01565	4.935e-58	205.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1I1XN@117743|Flavobacteriia	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
TLS3_k127_6799330_0	755732.Fluta_2315	7.751e-130	421.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1HX6Y@117743|Flavobacteriia,2PADM@246874|Cryomorphaceae	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
TLS3_k127_6799330_1	760192.Halhy_2815	6.163e-84	283.0	COG4330@1|root,COG4330@2|Bacteria,4NNT4@976|Bacteroidetes,1IY27@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
TLS3_k127_6799330_5	667015.Bacsa_2698	2.686e-25	109.0	COG0818@1|root,COG0818@2|Bacteria,4NQ39@976|Bacteroidetes,2FSJ8@200643|Bacteroidia,4AQWN@815|Bacteroidaceae	976|Bacteroidetes	M	Psort location CytoplasmicMembrane, score	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
TLS3_k127_6799330_2	755732.Fluta_3824	3.762e-82	279.0	COG1352@1|root,COG1352@2|Bacteria,4P3Q6@976|Bacteroidetes	976|Bacteroidetes	NT	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_6799330_4	153721.MYP_2890	2.729e-46	176.0	COG3584@1|root,COG3584@2|Bacteria	2|Bacteria	T	3D domain protein	-	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5,LysM
TLS3_k127_6799330_6	616991.JPOO01000003_gene16	9.724e-19	85.0	COG0598@1|root,COG0598@2|Bacteria,4NG3C@976|Bacteroidetes,1HXRX@117743|Flavobacteriia	976|Bacteroidetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
TLS3_k127_6799979_1	755732.Fluta_1117	1.529e-116	379.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1HWVA@117743|Flavobacteriia,2PAC5@246874|Cryomorphaceae	976|Bacteroidetes	M	TIGRFAM outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
TLS3_k127_6799979_4	755732.Fluta_1119	4.528e-69	239.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,1HXE0@117743|Flavobacteriia,2PAZQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Outer membrane protein (OmpH-like)	skp	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TLS3_k127_6799979_6	755732.Fluta_1120	8.396e-38	147.0	COG2825@1|root,COG2825@2|Bacteria,4PK8T@976|Bacteroidetes,1IGFF@117743|Flavobacteriia,2PC2K@246874|Cryomorphaceae	976|Bacteroidetes	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
TLS3_k127_6799979_2	755732.Fluta_1122	4.451e-110	362.0	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,1HX4S@117743|Flavobacteriia,2PB1C@246874|Cryomorphaceae	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
TLS3_k127_6799979_0	763034.HMPREF9446_01537	6.89e-133	435.0	COG0399@1|root,COG0399@2|Bacteria,4NEIU@976|Bacteroidetes,2FPX9@200643|Bacteroidia,4AVSC@815|Bacteroidaceae	976|Bacteroidetes	E	Aminotransferase class-V	wecE	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
TLS3_k127_6799979_3	1506583.JQJY01000005_gene2364	2.698e-94	319.0	COG0332@1|root,COG0332@2|Bacteria,4NFMX@976|Bacteroidetes,1IIN6@117743|Flavobacteriia,2NV2R@237|Flavobacterium	976|Bacteroidetes	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
TLS3_k127_6799979_7	1429851.X548_01015	2.166e-37	152.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1X9F6@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_6799979_9	1123511.KB905839_gene474	2.445e-09	67.0	COG1670@1|root,COG1670@2|Bacteria,1V7UX@1239|Firmicutes,4H61M@909932|Negativicutes	909932|Negativicutes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,Acetyltransf_4
TLS3_k127_6799979_5	592029.DDD_2273	2.878e-67	240.0	2EWJQ@1|root,33PXW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6799979_10	1144313.PMI10_00333	5.131e-05	46.0	COG1216@1|root,COG1216@2|Bacteria,4NIW6@976|Bacteroidetes,1IK7C@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_6799979_8	880071.Fleli_3190	3.352e-12	66.0	COG1215@1|root,COG1215@2|Bacteria,4PME9@976|Bacteroidetes,47JUK@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_6800081_1	755732.Fluta_1445	1.651e-115	377.0	COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,4NETR@976|Bacteroidetes,1HY3M@117743|Flavobacteriia,2PAJZ@246874|Cryomorphaceae	976|Bacteroidetes	M	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DUF2062,Glycos_transf_2
TLS3_k127_6800081_5	1121481.AUAS01000012_gene270	3.856e-26	114.0	2C56J@1|root,32YW7@2|Bacteria,4NUU4@976|Bacteroidetes,47X77@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6800081_2	1313421.JHBV01000012_gene4089	1.692e-100	336.0	COG0716@1|root,COG0716@2|Bacteria,4NHTB@976|Bacteroidetes,1ISM3@117747|Sphingobacteriia	976|Bacteroidetes	C	Dialkylrecorsinol condensing enzyme DarA	darA	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6800081_0	755732.Fluta_1447	1.68e-172	548.0	COG0332@1|root,COG0332@2|Bacteria,4NE5Q@976|Bacteroidetes,1HXY8@117743|Flavobacteriia,2PAEI@246874|Cryomorphaceae	976|Bacteroidetes	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal	darB	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III_C,Thiolase_N,ketoacyl-synt
TLS3_k127_6800081_4	926562.Oweho_0888	6.002e-50	181.0	2CE7N@1|root,30Q80@2|Bacteria,4NNKP@976|Bacteroidetes,1I2K6@117743|Flavobacteriia,2PB1Q@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6800081_3	755732.Fluta_1449	1.358e-69	237.0	COG4990@1|root,COG4990@2|Bacteria,4NFZX@976|Bacteroidetes,1HXZ6@117743|Flavobacteriia,2PACU@246874|Cryomorphaceae	976|Bacteroidetes	S	Butirosin biosynthesis protein H, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
TLS3_k127_681206_1	755732.Fluta_0956	2.231e-165	527.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1HXPM@117743|Flavobacteriia,2PAHX@246874|Cryomorphaceae	976|Bacteroidetes	L	Bacterial DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
TLS3_k127_681206_11	926550.CLDAP_33710	6.641e-37	156.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
TLS3_k127_681206_9	755732.Fluta_0959	1.272e-47	175.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia,2PAZS@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
TLS3_k127_681206_12	755732.Fluta_0958	1.912e-34	136.0	2A96H@1|root,30YB5@2|Bacteria,4PC34@976|Bacteroidetes,1IMTJ@117743|Flavobacteriia,2PC4Z@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
TLS3_k127_681206_7	755732.Fluta_0959	1.286e-62	218.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia,2PAZS@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
TLS3_k127_681206_5	755732.Fluta_0961	1.63e-87	292.0	COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,1HX7M@117743|Flavobacteriia,2PAPD@246874|Cryomorphaceae	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
TLS3_k127_681206_10	755732.Fluta_0962	1.88e-39	151.0	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,1I2XJ@117743|Flavobacteriia,2PB4X@246874|Cryomorphaceae	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
TLS3_k127_681206_3	755732.Fluta_0965	6.718e-152	482.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1HWTI@117743|Flavobacteriia,2PA62@246874|Cryomorphaceae	976|Bacteroidetes	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
TLS3_k127_681206_8	1123248.KB893327_gene796	2.094e-49	192.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NRVM@976|Bacteroidetes,1IQDC@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
TLS3_k127_681206_2	906888.JCM19314_625	3.255e-163	540.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes,1HXYN@117743|Flavobacteriia	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
TLS3_k127_681206_4	1408433.JHXV01000002_gene442	9.69e-89	312.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
TLS3_k127_681206_0	491205.JARQ01000005_gene1734	0.0	1336.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1HWJV@117743|Flavobacteriia,3ZNQC@59732|Chryseobacterium	976|Bacteroidetes	C	Aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
TLS3_k127_681206_6	755732.Fluta_2885	3.446e-68	259.0	COG3291@1|root,COG3291@2|Bacteria,4PI0H@976|Bacteroidetes,1IGQE@117743|Flavobacteriia,2PBJ6@246874|Cryomorphaceae	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
TLS3_k127_6818885_2	1121897.AUGO01000010_gene2753	1.576e-45	183.0	COG0457@1|root,COG3920@1|root,COG0457@2|Bacteria,COG3920@2|Bacteria,4NINT@976|Bacteroidetes,1HWYS@117743|Flavobacteriia,2NVMV@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_2,TPR_12,TPR_8
TLS3_k127_6818885_0	755732.Fluta_1566	1.166e-161	515.0	COG3177@1|root,COG3177@2|Bacteria,4NFBY@976|Bacteroidetes,1HXAM@117743|Flavobacteriia,2PAZI@246874|Cryomorphaceae	976|Bacteroidetes	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
TLS3_k127_6818885_1	755732.Fluta_1313	4.427e-161	516.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,1HWWM@117743|Flavobacteriia,2PAMP@246874|Cryomorphaceae	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
TLS3_k127_681969_0	755732.Fluta_0502	1.584e-220	689.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,1HYKT@117743|Flavobacteriia,2PA8G@246874|Cryomorphaceae	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
TLS3_k127_6824489_3	946077.W5A_08392	6.258e-116	375.0	COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,1HX7P@117743|Flavobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
TLS3_k127_6824489_4	1408433.JHXV01000010_gene577	1.918e-89	305.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,1HXR1@117743|Flavobacteriia,2PBNG@246874|Cryomorphaceae	976|Bacteroidetes	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
TLS3_k127_6824489_0	755732.Fluta_2610	0.0	1045.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,1HXV3@117743|Flavobacteriia,2PA95@246874|Cryomorphaceae	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
TLS3_k127_6824489_9	1122176.KB903532_gene2652	1.663e-22	100.0	COG0477@1|root,COG2814@2|Bacteria,4NUYS@976|Bacteroidetes	976|Bacteroidetes	EGP	TIGRFAM integral membrane protein	ydzA	-	-	-	-	-	-	-	-	-	-	-	DUF3817
TLS3_k127_6824489_2	755732.Fluta_2607	2.1e-124	401.0	COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,1IMQY@117743|Flavobacteriia,2PBHE@246874|Cryomorphaceae	976|Bacteroidetes	H	2-phosphosulpholactate phosphatase	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
TLS3_k127_6824489_1	755732.Fluta_2606	8.273e-158	503.0	28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,1I8RM@117743|Flavobacteriia	976|Bacteroidetes	S	S1 P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease,Zn_dep_PLPC
TLS3_k127_6824489_7	313603.FB2170_10241	7.343e-35	141.0	2C2AI@1|root,32RA3@2|Bacteria,4NQ4M@976|Bacteroidetes,1I3RG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6824489_5	1122176.KB903556_gene4095	1.558e-49	183.0	COG2897@1|root,COG2897@2|Bacteria,4NPVK@976|Bacteroidetes,1IYBU@117747|Sphingobacteriia	976|Bacteroidetes	P	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS3_k127_6824489_8	1177154.Y5S_03011	1.454e-32	135.0	COG3793@1|root,COG3793@2|Bacteria,1P6XA@1224|Proteobacteria,1SV9P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	zinc-ribbon family	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_15
TLS3_k127_6824489_6	1286632.P278_00790	8.02e-39	148.0	COG3070@1|root,COG3070@2|Bacteria,4NSGZ@976|Bacteroidetes,1I4CE@117743|Flavobacteriia	976|Bacteroidetes	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
TLS3_k127_6824489_10	1408433.JHXV01000006_gene2644	4.218e-18	84.0	COG4555@1|root,COG4555@2|Bacteria,4PNSV@976|Bacteroidetes,1IKBA@117743|Flavobacteriia,2PBF9@246874|Cryomorphaceae	976|Bacteroidetes	CP	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	-	ABC_tran
TLS3_k127_6824986_0	755732.Fluta_0535	3.616e-135	436.0	COG1555@1|root,COG1555@2|Bacteria,4NE88@976|Bacteroidetes,1I7MT@117743|Flavobacteriia,2PAFS@246874|Cryomorphaceae	976|Bacteroidetes	L	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
TLS3_k127_6824986_1	504472.Slin_3510	3.302e-17	82.0	COG3801@1|root,COG3801@2|Bacteria,4NSK5@976|Bacteroidetes,47RTD@768503|Cytophagia	976|Bacteroidetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
TLS3_k127_6827839_2	1233951.IO90_17280	1.756e-104	348.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,1HZAE@117743|Flavobacteriia,3HH29@358033|Chryseobacterium	976|Bacteroidetes	F	Bacterial capsule synthesis protein PGA_cap	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
TLS3_k127_6827839_4	867902.Ornrh_1490	5.413e-27	119.0	COG0737@1|root,COG0737@2|Bacteria,4NR6D@976|Bacteroidetes,1HXWU@117743|Flavobacteriia	976|Bacteroidetes	F	5'-nucleotidase	ushA	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C
TLS3_k127_6827839_1	755732.Fluta_2742	5.821e-251	795.0	COG2356@1|root,COG4085@1|root,COG2356@2|Bacteria,COG4085@2|Bacteria	2|Bacteria	S	PFAM nucleic acid binding, OB-fold, tRNA	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,PLDc_2,Trypsin_2
TLS3_k127_6827839_0	755732.Fluta_2741	0.0	1054.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4PIMA@976|Bacteroidetes,1ICC3@117743|Flavobacteriia,2PBZQ@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug
TLS3_k127_6827839_3	755732.Fluta_2740	1.912e-103	345.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_6842827_2	1227739.Hsw_2607	8.712e-56	209.0	COG0438@1|root,COG0438@2|Bacteria,4NKNB@976|Bacteroidetes,47RYJ@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	ko:K12989	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_6842827_0	755732.Fluta_0377	1.357e-180	579.0	COG4191@1|root,COG4191@2|Bacteria,4NEMP@976|Bacteroidetes,1HY7G@117743|Flavobacteriia,2PAKB@246874|Cryomorphaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	vicK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
TLS3_k127_6842827_1	755732.Fluta_0701	9.782e-136	445.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6852724_1	755732.Fluta_2408	3.817e-83	284.0	2E7J5@1|root,3321E@2|Bacteria,4NWSR@976|Bacteroidetes,1I9ID@117743|Flavobacteriia,2PB0F@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
TLS3_k127_6852724_0	755732.Fluta_2407	3.789e-182	575.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,1HX2U@117743|Flavobacteriia,2PAHJ@246874|Cryomorphaceae	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
TLS3_k127_6861026_3	926559.JoomaDRAFT_3524	3.706e-35	137.0	COG0790@1|root,COG0790@2|Bacteria,4NGW3@976|Bacteroidetes,1HY27@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
TLS3_k127_6861026_1	1121904.ARBP01000001_gene5643	6.872e-79	281.0	28JIH@1|root,2Z9BT@2|Bacteria,4NIF7@976|Bacteroidetes,47SD9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999
TLS3_k127_6861026_2	290315.Clim_1284	1.874e-35	144.0	COG4704@1|root,COG4704@2|Bacteria,1FF7S@1090|Chlorobi	1090|Chlorobi	S	Fibrobacter succinogenes major domain (Fib_succ_major)	-	-	-	-	-	-	-	-	-	-	-	-	Fib_succ_major
TLS3_k127_6861026_0	906888.JCM19314_982	2.332e-184	608.0	COG5373@1|root,COG5373@2|Bacteria,4NGKV@976|Bacteroidetes,1HZB4@117743|Flavobacteriia,3HJEE@363408|Nonlabens	976|Bacteroidetes	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
TLS3_k127_6865915_2	1313421.JHBV01000020_gene5205	9.867e-38	146.0	COG3025@1|root,COG3025@2|Bacteria,4NM6K@976|Bacteroidetes	976|Bacteroidetes	S	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
TLS3_k127_6865915_0	1313421.JHBV01000020_gene5204	1.246e-88	297.0	arCOG14808@1|root,308PC@2|Bacteria,4NR4D@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
TLS3_k127_6865915_1	755732.Fluta_2848	2.013e-84	291.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,1HWU8@117743|Flavobacteriia,2PAS0@246874|Cryomorphaceae	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
TLS3_k127_6871505_3	755732.Fluta_2847	7.436e-133	425.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,1HWSP@117743|Flavobacteriia,2PA74@246874|Cryomorphaceae	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
TLS3_k127_6871505_1	755732.Fluta_2846	3.146e-223	700.0	COG0064@1|root,COG0064@2|Bacteria,4NF3B@976|Bacteroidetes,1I8AX@117743|Flavobacteriia,2PAB3@246874|Cryomorphaceae	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
TLS3_k127_6871505_5	755732.Fluta_2845	2.239e-109	366.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1HY1W@117743|Flavobacteriia,2PAW1@246874|Cryomorphaceae	976|Bacteroidetes	CO	Thioredoxin-like	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
TLS3_k127_6871505_6	755732.Fluta_2844	2.155e-95	324.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1HY1W@117743|Flavobacteriia,2PBB8@246874|Cryomorphaceae	976|Bacteroidetes	CO	Glutathione peroxidase	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
TLS3_k127_6871505_4	926562.Oweho_2422	9.824e-112	365.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1HWZZ@117743|Flavobacteriia,2PADT@246874|Cryomorphaceae	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
TLS3_k127_6871505_0	755732.Fluta_2893	1.513e-239	745.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,1HXT4@117743|Flavobacteriia,2PA68@246874|Cryomorphaceae	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
TLS3_k127_6871505_2	1120965.AUBV01000006_gene2282	1.217e-178	571.0	COG1757@1|root,COG1757@2|Bacteria,4NFQT@976|Bacteroidetes,47KKY@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM Na H antiporter NhaC	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
TLS3_k127_6871505_7	1408433.JHXV01000026_gene3047	1.003e-40	153.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1HYND@117743|Flavobacteriia,2PA5Y@246874|Cryomorphaceae	976|Bacteroidetes	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
TLS3_k127_688313_3	402612.FP1830	2.343e-14	88.0	COG3391@1|root,COG4412@1|root,COG4733@1|root,COG3391@2|Bacteria,COG4412@2|Bacteria,COG4733@2|Bacteria,4PMS8@976|Bacteroidetes,1IJYE@117743|Flavobacteriia,2P0PK@237|Flavobacterium	976|Bacteroidetes	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_688313_2	673862.BABL1_1004	3.876e-50	205.0	COG3209@1|root,COG3209@2|Bacteria,1QW4H@1224|Proteobacteria,42ZEZ@68525|delta/epsilon subdivisions,2WT5G@28221|Deltaproteobacteria	1224|Proteobacteria	M	Immunoglobulin-like repeats containing protein domain	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Autotransporter,Big_3_5,DUF4347,He_PIG,RHS_repeat
TLS3_k127_688313_1	1249975.JQLP01000005_gene2507	2.911e-67	240.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HWKC@117743|Flavobacteriia,2P5GH@244698|Gillisia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_688313_0	1185876.BN8_02873	4.788e-96	342.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47K1N@768503|Cytophagia	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
TLS3_k127_6883823_0	755732.Fluta_1555	0.0	1393.0	COG1078@1|root,COG2114@1|root,COG3292@1|root,COG1078@2|Bacteria,COG2114@2|Bacteria,COG3292@2|Bacteria,4PP0F@976|Bacteroidetes,1IKDF@117743|Flavobacteriia,2PBK0@246874|Cryomorphaceae	976|Bacteroidetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Reg_prop,Y_Y_Y
TLS3_k127_6883823_1	755732.Fluta_1554	2.911e-57	201.0	COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,1HY16@117743|Flavobacteriia,2PAVC@246874|Cryomorphaceae	976|Bacteroidetes	C	Ferritin-like domain	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
TLS3_k127_6896715_4	1121373.KB903630_gene302	3.49e-12	71.0	COG0789@1|root,COG0789@2|Bacteria,4NERC@976|Bacteroidetes,47K07@768503|Cytophagia	976|Bacteroidetes	K	PFAM MerR family regulatory protein	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
TLS3_k127_6896715_2	1121890.AUDO01000003_gene1893	3.577e-30	124.0	COG1544@1|root,COG1544@2|Bacteria,4NUWT@976|Bacteroidetes,1I6JI@117743|Flavobacteriia,2NX9H@237|Flavobacterium	976|Bacteroidetes	J	Ribosomal subunit interface protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
TLS3_k127_6896715_3	760192.Halhy_5677	4.454e-16	83.0	2AF5K@1|root,3154F@2|Bacteria,4PJCD@976|Bacteroidetes,1J00F@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6896715_1	1168289.AJKI01000051_gene829	1.247e-52	189.0	COG0454@1|root,COG0456@2|Bacteria,4NQ9E@976|Bacteroidetes,2FY34@200643|Bacteroidia,3XKQN@558415|Marinilabiliaceae	976|Bacteroidetes	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
TLS3_k127_6896715_0	1380384.JADN01000008_gene1251	5.632e-98	323.0	COG3457@1|root,COG3457@2|Bacteria,4NFEJ@976|Bacteroidetes,1HYZY@117743|Flavobacteriia	976|Bacteroidetes	E	amino acid racemase	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
TLS3_k127_6905788_1	755732.Fluta_1199	3.176e-68	246.0	COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,1HXB9@117743|Flavobacteriia,2PBVJ@246874|Cryomorphaceae	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
TLS3_k127_6905788_0	755732.Fluta_1200	5.727e-189	594.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,1HXSA@117743|Flavobacteriia,2PAJH@246874|Cryomorphaceae	976|Bacteroidetes	I	B12 binding domain	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
TLS3_k127_6914166_1	755732.Fluta_3159	1.308e-141	464.0	2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,1HXZZ@117743|Flavobacteriia,2PAX7@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
TLS3_k127_6914166_0	755732.Fluta_3949	0.0	1253.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1HWKZ@117743|Flavobacteriia,2PA6N@246874|Cryomorphaceae	976|Bacteroidetes	S	Glutamine synthetase type III N terminal	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
TLS3_k127_6914166_2	1392488.JHZY01000004_gene3112	1.251e-21	96.0	COG0520@1|root,COG0520@2|Bacteria,4NM0W@976|Bacteroidetes,1I00M@117743|Flavobacteriia,2XJWU@283735|Leeuwenhoekiella	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
TLS3_k127_6923190_0	755732.Fluta_2761	2.093e-181	573.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,1HX15@117743|Flavobacteriia,2PAKR@246874|Cryomorphaceae	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
TLS3_k127_6923190_3	329726.AM1_6347	6.421e-22	104.0	COG5513@1|root,COG5513@2|Bacteria	2|Bacteria	G	serine-type aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
TLS3_k127_6923190_1	755732.Fluta_2014	1.946e-52	189.0	COG0295@1|root,COG0295@2|Bacteria,4NQED@976|Bacteroidetes,1I1A3@117743|Flavobacteriia	976|Bacteroidetes	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
TLS3_k127_6923190_2	1408433.JHXV01000021_gene1640	3.813e-32	125.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,1HWYI@117743|Flavobacteriia,2PAD9@246874|Cryomorphaceae	976|Bacteroidetes	J	Uncharacterized protein family UPF0004	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
TLS3_k127_6948543_18	391587.KAOT1_19412	1.032e-19	91.0	COG1032@1|root,COG1032@2|Bacteria,4NM2X@976|Bacteroidetes,1I8A5@117743|Flavobacteriia	976|Bacteroidetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
TLS3_k127_6948543_14	391587.KAOT1_19402	1.037e-42	174.0	28X89@1|root,2ZJ6D@2|Bacteria,4NM59@976|Bacteroidetes,1I885@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_6948543_12	1107311.Q767_06875	3.582e-53	201.0	COG0438@1|root,COG0438@2|Bacteria,4NPXB@976|Bacteroidetes,1I7TH@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
TLS3_k127_6948543_15	391587.KAOT1_19432	9.887e-40	158.0	COG0500@1|root,COG2226@2|Bacteria,4NQRA@976|Bacteroidetes,1I70W@117743|Flavobacteriia	976|Bacteroidetes	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
TLS3_k127_6948543_6	1408433.JHXV01000016_gene1839	2.025e-157	508.0	COG1032@1|root,COG1032@2|Bacteria,4NKFV@976|Bacteroidetes,1HXZP@117743|Flavobacteriia	976|Bacteroidetes	C	COG1032 Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
TLS3_k127_6948543_11	1469557.JSWF01000031_gene2013	8.871e-54	198.0	COG0500@1|root,COG2226@2|Bacteria,4NICK@976|Bacteroidetes,1I0JJ@117743|Flavobacteriia	976|Bacteroidetes	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_6948543_5	1121897.AUGO01000001_gene1221	1.034e-173	558.0	COG1032@1|root,COG1032@2|Bacteria,4NETM@976|Bacteroidetes,1HYTW@117743|Flavobacteriia,2NV98@237|Flavobacterium	976|Bacteroidetes	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
TLS3_k127_6948543_8	391587.KAOT1_19557	2.077e-70	249.0	COG1708@1|root,COG1708@2|Bacteria,4NPRU@976|Bacteroidetes,1I105@117743|Flavobacteriia	976|Bacteroidetes	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
TLS3_k127_6948543_13	755732.Fluta_1825	5.278e-52	187.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,1I30B@117743|Flavobacteriia,2PB9N@246874|Cryomorphaceae	976|Bacteroidetes	I	Biotin-requiring enzyme	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
TLS3_k127_6948543_0	755732.Fluta_1824	4.297e-292	923.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,4NFTN@976|Bacteroidetes,1HXC0@117743|Flavobacteriia,2PBRD@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Peptidase family M1	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
TLS3_k127_6948543_17	755732.Fluta_0854	1.167e-28	128.0	COG3391@1|root,COG3391@2|Bacteria,4P8JP@976|Bacteroidetes	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6948543_1	867900.Celly_3140	1.126e-255	803.0	COG1226@1|root,COG1226@2|Bacteria,4NMQN@976|Bacteroidetes,1I7BA@117743|Flavobacteriia	976|Bacteroidetes	P	Castor and Pollux, part of voltage-gated ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Castor_Poll_mid
TLS3_k127_6948543_9	886377.Murru_3032	8.595e-62	216.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1I16V@117743|Flavobacteriia	976|Bacteroidetes	O	Thiol peroxidase	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
TLS3_k127_6948543_4	755732.Fluta_1658	1.134e-183	579.0	COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,1HY3S@117743|Flavobacteriia,2PAC2@246874|Cryomorphaceae	976|Bacteroidetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
TLS3_k127_6948543_2	755732.Fluta_3528	1.488e-212	674.0	COG1233@1|root,COG1233@2|Bacteria,4P24Z@976|Bacteroidetes,1IITR@117743|Flavobacteriia	976|Bacteroidetes	C	COGs COG1233 Phytoene dehydrogenase and related protein	-	-	5.2.1.13	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R07512	RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_8
TLS3_k127_6948543_20	1237149.C900_01254	0.0001047	56.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria,4NF1M@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,Peptidase_S8_N
TLS3_k127_6948543_3	1313421.JHBV01000007_gene4209	8.633e-204	676.0	COG3291@1|root,COG3291@2|Bacteria,4PMDA@976|Bacteroidetes	976|Bacteroidetes	O	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
TLS3_k127_6948543_10	945713.IALB_2578	9.327e-61	230.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase
TLS3_k127_6948543_16	1237149.C900_03163	3.057e-37	154.0	COG1597@1|root,COG1597@2|Bacteria,4NGPY@976|Bacteroidetes,47R07@768503|Cytophagia	976|Bacteroidetes	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
TLS3_k127_6948543_19	616991.JPOO01000001_gene4315	3.387e-13	76.0	COG4659@1|root,COG4659@2|Bacteria,4NPUB@976|Bacteroidetes,1I2MB@117743|Flavobacteriia,23HDD@178469|Arenibacter	976|Bacteroidetes	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
TLS3_k127_6948543_7	1168289.AJKI01000044_gene52	2.721e-104	350.0	COG1730@1|root,COG1730@2|Bacteria,4NHZT@976|Bacteroidetes,2FMBH@200643|Bacteroidia	976|Bacteroidetes	O	unfolded protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
TLS3_k127_6956253_0	1408433.JHXV01000036_gene269	5.983e-147	471.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1HXSP@117743|Flavobacteriia,2PA4G@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
TLS3_k127_6956253_1	755732.Fluta_0258	1.967e-60	220.0	2FG80@1|root,3484C@2|Bacteria,4P5E2@976|Bacteroidetes,1IAKI@117743|Flavobacteriia,2PB7R@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6976220_2	755732.Fluta_2594	5.464e-70	241.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1HWYE@117743|Flavobacteriia,2PAIE@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Alanine dehydrogenase PNT, C-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
TLS3_k127_6976220_3	755732.Fluta_2593	1.588e-39	153.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,1I3XP@117743|Flavobacteriia,2PB2X@246874|Cryomorphaceae	976|Bacteroidetes	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	tsaE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
TLS3_k127_6976220_0	755732.Fluta_2592	6.218e-242	756.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,1HY11@117743|Flavobacteriia,2PAEX@246874|Cryomorphaceae	976|Bacteroidetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
TLS3_k127_6976220_1	755732.Fluta_2591	6.945e-96	319.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1HXQF@117743|Flavobacteriia,2PA4F@246874|Cryomorphaceae	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
TLS3_k127_6982368_1	1341155.FSS13T_21340	1.325e-152	490.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,1HWX8@117743|Flavobacteriia,2NTJD@237|Flavobacterium	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
TLS3_k127_6982368_0	755732.Fluta_3531	4.036e-300	949.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1HX49@117743|Flavobacteriia,2PA7Q@246874|Cryomorphaceae	976|Bacteroidetes	GV	PFAM Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3
TLS3_k127_7005404_6	755732.Fluta_3628	1.684e-77	263.0	COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,1HX2Z@117743|Flavobacteriia,2PASZ@246874|Cryomorphaceae	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS3_k127_7005404_1	755732.Fluta_3292	8.117e-145	464.0	COG3176@1|root,COG3176@2|Bacteria,4PKEK@976|Bacteroidetes,1IK29@117743|Flavobacteriia,2PA9V@246874|Cryomorphaceae	976|Bacteroidetes	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
TLS3_k127_7005404_5	755732.Fluta_3293	1.42e-93	315.0	COG0204@1|root,COG0204@2|Bacteria,4NF25@976|Bacteroidetes,1IMPQ@117743|Flavobacteriia,2PANX@246874|Cryomorphaceae	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TLS3_k127_7005404_0	755732.Fluta_2362	4.068e-173	553.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,1HYA7@117743|Flavobacteriia,2PAKM@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_7005404_4	755732.Fluta_2363	5.562e-105	351.0	COG2870@1|root,COG2870@2|Bacteria,4NHUV@976|Bacteroidetes,1ICPR@117743|Flavobacteriia,2PBJC@246874|Cryomorphaceae	976|Bacteroidetes	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
TLS3_k127_7005404_2	1279009.ADICEAN_01993	6.18e-129	433.0	COG0168@1|root,COG0168@2|Bacteria,4NF7R@976|Bacteroidetes,47JIP@768503|Cytophagia	976|Bacteroidetes	P	PFAM Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
TLS3_k127_7005404_3	755732.Fluta_2364	6.667e-115	374.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,1HX52@117743|Flavobacteriia,2PA5X@246874|Cryomorphaceae	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
TLS3_k127_7005404_7	755732.Fluta_2365	1.349e-67	237.0	2C52N@1|root,315JU@2|Bacteria,4PJRQ@976|Bacteroidetes,1IE9T@117743|Flavobacteriia,2PB34@246874|Cryomorphaceae	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_7005885_3	1121481.AUAS01000011_gene5147	3.56e-44	165.0	COG0107@1|root,COG0107@2|Bacteria,4NM6U@976|Bacteroidetes,47PCG@768503|Cytophagia	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	-	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
TLS3_k127_7005885_1	344747.PM8797T_18684	3.742e-54	196.0	COG0118@1|root,COG0118@2|Bacteria,2IYXZ@203682|Planctomycetes	203682|Planctomycetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
TLS3_k127_7005885_2	323259.Mhun_2376	5.147e-52	199.0	COG0438@1|root,arCOG01403@2157|Archaea,2Y2AX@28890|Euryarchaeota,2NAPJ@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
TLS3_k127_7005885_0	1279009.ADICEAN_01121	3.25e-105	349.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
TLS3_k127_7005885_4	96561.Dole_2627	6.035e-20	100.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_2,Methyltransf_23
TLS3_k127_7005885_5	1500281.JQKZ01000054_gene2066	0.0007204	44.0	28NA0@1|root,2ZBDV@2|Bacteria,4NJGM@976|Bacteroidetes,1HZQ5@117743|Flavobacteriia,3ZQ1R@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4906,Fib_succ_major
TLS3_k127_7007954_1	643867.Ftrac_2035	2.293e-78	267.0	COG3016@1|root,COG3016@2|Bacteria,4NEQ4@976|Bacteroidetes,47MCF@768503|Cytophagia	976|Bacteroidetes	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
TLS3_k127_7007954_2	755732.Fluta_3449	1.615e-47	181.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K03686,ko:K05801,ko:K17867	-	-	-	-	ko00000,ko03012,ko03029,ko03110	-	-	-	DnaJ,TerB
TLS3_k127_7007954_0	755732.Fluta_0075	7.892e-88	295.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,1HYG2@117743|Flavobacteriia,2PARB@246874|Cryomorphaceae	976|Bacteroidetes	S	Bacterial transferase hexapeptide (six repeats)	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
TLS3_k127_7007954_3	1121897.AUGO01000007_gene478	1.798e-15	76.0	COG5562@1|root,COG5562@2|Bacteria,4NR3A@976|Bacteroidetes,1I3BI@117743|Flavobacteriia,2NWDV@237|Flavobacterium	976|Bacteroidetes	S	Phage envelope protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1398
TLS3_k127_7013525_4	755732.Fluta_1496	1.135e-73	273.0	COG3850@1|root,COG5000@1|root,COG3850@2|Bacteria,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,1HXA7@117743|Flavobacteriia,2PANS@246874|Cryomorphaceae	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_7013525_3	755732.Fluta_1497	1.476e-85	287.0	COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes,1HXSB@117743|Flavobacteriia,2PBVK@246874|Cryomorphaceae	976|Bacteroidetes	F	Phosphoribulokinase / Uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
TLS3_k127_7013525_6	755732.Fluta_1499	5.647e-56	203.0	COG0526@1|root,COG0526@2|Bacteria,4PKPR@976|Bacteroidetes,1IJG9@117743|Flavobacteriia,2PBSY@246874|Cryomorphaceae	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
TLS3_k127_7013525_1	755732.Fluta_1500	2.917e-195	630.0	COG3591@1|root,COG3591@2|Bacteria,4NG2K@976|Bacteroidetes,1IKDE@117743|Flavobacteriia,2PBR5@246874|Cryomorphaceae	976|Bacteroidetes	E	Belongs to the peptidase S1B family	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Trypsin,Trypsin_2
TLS3_k127_7013525_11	926562.Oweho_2093	2.083e-06	59.0	COG3291@1|root,COG3291@2|Bacteria,4NI4A@976|Bacteroidetes,1I0P7@117743|Flavobacteriia,2PBKJ@246874|Cryomorphaceae	976|Bacteroidetes	O	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Cleaved_Adhesin,MAM,PKD,fn3
TLS3_k127_7013525_0	755732.Fluta_1400	1.659e-263	816.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia,2PAF7@246874|Cryomorphaceae	976|Bacteroidetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.32,1.2.1.85	ko:K10217	ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220	M00038,M00569	R02762,R03889,R05353	RC00218,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_7013525_9	553219.CAMSH0001_1454	1.067e-10	67.0	COG5652@1|root,COG5652@2|Bacteria,1N9QA@1224|Proteobacteria,43B7W@68525|delta/epsilon subdivisions,2YT6M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
TLS3_k127_7013525_2	755732.Fluta_1348	7.317e-107	358.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,1HWJX@117743|Flavobacteriia,2PAAZ@246874|Cryomorphaceae	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
TLS3_k127_7013525_7	926559.JoomaDRAFT_3734	1.553e-25	109.0	COG1235@1|root,COG1235@2|Bacteria,4NGB4@976|Bacteroidetes,1HYHP@117743|Flavobacteriia	976|Bacteroidetes	S	Pyrroloquinoline quinone biosynthesis protein PqqB	-	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
TLS3_k127_7013525_10	1121875.KB907547_gene3446	3.018e-09	58.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12,TPR_8
TLS3_k127_7013855_3	755732.Fluta_3558	4.659e-65	230.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,1I942@117743|Flavobacteriia,2PBH5@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran
TLS3_k127_7013855_4	755732.Fluta_3557	8.333e-57	200.0	290ZX@1|root,2ZNMM@2|Bacteria,4P891@976|Bacteroidetes,1ICSI@117743|Flavobacteriia,2PC01@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7013855_1	755732.Fluta_3556	6.944e-84	288.0	29N3N@1|root,32D2M@2|Bacteria,4NRTM@976|Bacteroidetes,1ICPZ@117743|Flavobacteriia,2PBKH@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7013855_0	755732.Fluta_3555	8.063e-155	494.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1HX0W@117743|Flavobacteriia,2PAA0@246874|Cryomorphaceae	976|Bacteroidetes	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
TLS3_k127_7013855_2	755732.Fluta_3658	2.947e-76	266.0	COG1994@1|root,COG1994@2|Bacteria,4PAWF@976|Bacteroidetes,1IMS5@117743|Flavobacteriia,2PBVA@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7013855_5	755732.Fluta_3657	1.637e-10	68.0	COG1193@1|root,COG1193@2|Bacteria,4NNNV@976|Bacteroidetes,1I1ZP@117743|Flavobacteriia,2PB98@246874|Cryomorphaceae	976|Bacteroidetes	L	DNA mismatch repair protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2027,Smr
TLS3_k127_7047359_6	1461577.CCMH01000004_gene1346	6.693e-50	184.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1HXTJ@117743|Flavobacteriia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
TLS3_k127_7047359_5	755732.Fluta_3155	9.88e-63	227.0	COG2755@1|root,COG2755@2|Bacteria,4NFN6@976|Bacteroidetes,1HX8X@117743|Flavobacteriia,2PBQQ@246874|Cryomorphaceae	976|Bacteroidetes	E	GSCFA family	-	-	-	-	-	-	-	-	-	-	-	-	GSCFA
TLS3_k127_7047359_4	755732.Fluta_3157	1.292e-70	243.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I1A4@117743|Flavobacteriia,2PBNV@246874|Cryomorphaceae	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_7047359_0	1408433.JHXV01000010_gene585	2.762e-168	532.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1HWSA@117743|Flavobacteriia,2PAH9@246874|Cryomorphaceae	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
TLS3_k127_7047359_2	755732.Fluta_3578	8.986e-125	414.0	COG3391@1|root,COG3391@2|Bacteria,4PBC0@976|Bacteroidetes,1IMR3@117743|Flavobacteriia,2PBJ5@246874|Cryomorphaceae	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7047359_1	1223410.KN050846_gene285	3.229e-142	466.0	COG3291@1|root,COG3291@2|Bacteria,4PKMZ@976|Bacteroidetes,1I9DA@117743|Flavobacteriia	976|Bacteroidetes	S	TIGRFAM Por secretion system C-terminal sorting domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7047359_3	1341155.FSS13T_23610	2.695e-81	272.0	COG3832@1|root,COG3832@2|Bacteria,4NQ55@976|Bacteroidetes,1I3E7@117743|Flavobacteriia,2NVWM@237|Flavobacterium	976|Bacteroidetes	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_7057433_6	755732.Fluta_3573	5.119e-09	57.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,1HXJD@117743|Flavobacteriia,2PAB0@246874|Cryomorphaceae	976|Bacteroidetes	K	ParB-like nuclease domain	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
TLS3_k127_7057433_4	755732.Fluta_3574	1.72e-44	169.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,1I18T@117743|Flavobacteriia,2PB3D@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7057433_1	755732.Fluta_3575	7.473e-81	276.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1HX1D@117743|Flavobacteriia,2PATA@246874|Cryomorphaceae	976|Bacteroidetes	E	Dihydrodipicolinate reductase, C-terminus	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
TLS3_k127_7057433_0	755732.Fluta_3576	1.802e-217	692.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1HY4X@117743|Flavobacteriia,2PARP@246874|Cryomorphaceae	976|Bacteroidetes	U	TIGRFAM signal peptidase I, bacterial type	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
TLS3_k127_7057433_5	111105.HR09_01305	2.474e-35	143.0	COG0224@1|root,COG0224@2|Bacteria,4NM5H@976|Bacteroidetes,2FNPU@200643|Bacteroidia,22XN5@171551|Porphyromonadaceae	976|Bacteroidetes	C	WbqC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
TLS3_k127_7057433_3	1121373.KB903632_gene501	8.929e-59	217.0	COG2374@1|root,COG2374@2|Bacteria,4NEHG@976|Bacteroidetes,47JZ4@768503|Cytophagia	976|Bacteroidetes	S	Endonuclease exonuclease phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_7057433_2	234267.Acid_0755	3.839e-80	275.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,3Y3IF@57723|Acidobacteria	57723|Acidobacteria	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
TLS3_k127_7063025_0	379066.GAU_3728	1.194e-156	515.0	COG1479@1|root,COG1479@2|Bacteria	2|Bacteria	U	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1,DUF1524,DUF262
TLS3_k127_707201_3	1218108.KB908292_gene1477	3.122e-42	156.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1HWJY@117743|Flavobacteriia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
TLS3_k127_707201_2	755732.Fluta_3457	8.997e-91	306.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,1HWQK@117743|Flavobacteriia,2PAQ7@246874|Cryomorphaceae	976|Bacteroidetes	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
TLS3_k127_707201_0	755732.Fluta_3456	5.854e-145	483.0	COG2304@1|root,COG2304@2|Bacteria,4NFQQ@976|Bacteroidetes,1HYC9@117743|Flavobacteriia,2PAN5@246874|Cryomorphaceae	976|Bacteroidetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA
TLS3_k127_707201_1	755732.Fluta_3455	2.084e-136	445.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,1HZ2V@117743|Flavobacteriia,2PAD2@246874|Cryomorphaceae	976|Bacteroidetes	F	dihydroorotase	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
TLS3_k127_707201_4	755732.Fluta_3454	4.863e-27	113.0	COG3963@1|root,COG3963@2|Bacteria,4NPMV@976|Bacteroidetes,1I1YR@117743|Flavobacteriia,2PBV6@246874|Cryomorphaceae	976|Bacteroidetes	I	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	MTS,Methyltransf_12,Methyltransf_25,RrnaAD
TLS3_k127_7081382_1	755732.Fluta_1572	1.01e-272	850.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1HWQN@117743|Flavobacteriia,2PAIQ@246874|Cryomorphaceae	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
TLS3_k127_7081382_3	755732.Fluta_0639	1.407e-94	317.0	28IS5@1|root,2Z8RB@2|Bacteria,4NIIH@976|Bacteroidetes,1HZWV@117743|Flavobacteriia,2PBT8@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7081382_5	880071.Fleli_2853	2.841e-43	171.0	2DTFG@1|root,32UV5@2|Bacteria,4NUG9@976|Bacteroidetes,47UM6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7081382_4	755732.Fluta_1350	1.622e-85	293.0	COG0860@1|root,COG0860@2|Bacteria,4NHTN@976|Bacteroidetes,1I0TP@117743|Flavobacteriia,2PBHY@246874|Cryomorphaceae	976|Bacteroidetes	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
TLS3_k127_7081382_0	1356852.N008_20905	0.0	1410.0	COG0286@1|root,COG0286@2|Bacteria,4NG0E@976|Bacteroidetes,47M6Z@768503|Cytophagia	976|Bacteroidetes	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
TLS3_k127_71081_2	755732.Fluta_1542	1.266e-22	98.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I28F@117743|Flavobacteriia,2PAZ5@246874|Cryomorphaceae	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_71081_3	1408433.JHXV01000015_gene1718	1.192e-12	78.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
TLS3_k127_71081_0	1408433.JHXV01000005_gene2347	1.414e-43	167.0	2BNB7@1|root,32GYU@2|Bacteria,4NQDS@976|Bacteroidetes,1ICNB@117743|Flavobacteriia,2PB7H@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_71081_1	1313421.JHBV01000012_gene4087	2.322e-33	139.0	28IKZ@1|root,2Z8MJ@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1702)	-	-	-	ko:K21161	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002	-	-	-	DUF1702
TLS3_k127_7112043_13	1349785.BAUG01000003_gene284	1.715e-30	125.0	2E3PY@1|root,32YMY@2|Bacteria,4NVJZ@976|Bacteroidetes,1I753@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7112043_1	992406.RIA_1707	9.137e-201	632.0	COG0175@1|root,COG0175@2|Bacteria,4NDWR@976|Bacteroidetes,1HZEH@117743|Flavobacteriia	976|Bacteroidetes	EH	Phosphoadenosine phosphosulfate reductase family	-	-	-	ko:K19170	-	-	-	-	ko00000,ko02048	-	-	-	PAPS_reduct
TLS3_k127_7112043_2	880071.Fleli_1790	4.611e-190	614.0	COG1196@1|root,COG1196@2|Bacteria,4NHRS@976|Bacteroidetes,47SUH@768503|Cytophagia	976|Bacteroidetes	D	DNA sulfur modification protein DndD	dndD	-	-	ko:K19171	-	-	-	-	ko00000,ko02048	-	-	-	AAA_23
TLS3_k127_7112043_7	1041826.FCOL_09285	8.146e-64	235.0	COG2801@1|root,COG2801@2|Bacteria,4NTJY@976|Bacteroidetes,1I37S@117743|Flavobacteriia	976|Bacteroidetes	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve
TLS3_k127_7112043_16	469618.FVAG_01518	1.164e-09	63.0	COG2849@1|root,COG2849@2|Bacteria,37BZV@32066|Fusobacteria	32066|Fusobacteria	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_7112043_10	1317122.ATO12_06890	1.016e-47	190.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,1HYTK@117743|Flavobacteriia,2YM4I@290174|Aquimarina	976|Bacteroidetes	M	RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,TSP_3
TLS3_k127_7112043_12	1202532.FF52_00415	1.049e-36	142.0	COG2077@1|root,COG2077@2|Bacteria,4NNGR@976|Bacteroidetes,1I1D0@117743|Flavobacteriia,2NTS4@237|Flavobacterium	976|Bacteroidetes	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
TLS3_k127_7112043_8	869213.JCM21142_31278	1.163e-54	201.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NHSC@976|Bacteroidetes,47XEJ@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Reg_prop,SpoIIE,Y_Y_Y
TLS3_k127_7112043_6	984262.SGRA_0341	2.828e-70	261.0	COG1807@1|root,COG1807@2|Bacteria,4NP7Y@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7112043_11	1408433.JHXV01000005_gene2413	3.91e-41	158.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
TLS3_k127_7112043_14	1550091.JROE01000008_gene3503	3.504e-11	70.0	COG3637@1|root,COG3637@2|Bacteria,4NRN4@976|Bacteroidetes,1ITPS@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7112043_4	755732.Fluta_1729	1.094e-103	344.0	COG3781@1|root,COG3781@2|Bacteria,4NEB1@976|Bacteroidetes,1HYDP@117743|Flavobacteriia,2PAP9@246874|Cryomorphaceae	976|Bacteroidetes	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
TLS3_k127_7112043_5	755732.Fluta_1675	1.303e-84	286.0	COG0637@1|root,COG0637@2|Bacteria,4NID6@976|Bacteroidetes,1HZWD@117743|Flavobacteriia,2PBQZ@246874|Cryomorphaceae	976|Bacteroidetes	S	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	3.1.3.23	ko:K19270	-	-	-	-	ko00000,ko01000	-	-	-	HAD_2
TLS3_k127_7112043_9	755732.Fluta_1676	2.383e-50	189.0	COG3386@1|root,COG3386@2|Bacteria,4NK29@976|Bacteroidetes,1HZAI@117743|Flavobacteriia,2PB0I@246874|Cryomorphaceae	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
TLS3_k127_7112043_3	755732.Fluta_1841	3.03e-143	465.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,1HWV0@117743|Flavobacteriia,2PA4U@246874|Cryomorphaceae	976|Bacteroidetes	S	Transporter associated domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
TLS3_k127_7112043_0	755732.Fluta_1840	2.24e-214	673.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,1HXGE@117743|Flavobacteriia,2PA57@246874|Cryomorphaceae	976|Bacteroidetes	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
TLS3_k127_7112043_15	755732.Fluta_1839	2.601e-10	61.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1I7EW@117743|Flavobacteriia,2PBJ8@246874|Cryomorphaceae	976|Bacteroidetes	F	CobB/CobQ-like glutamine amidotransferase domain	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
TLS3_k127_7115063_2	1353276.JADR01000007_gene1412	8.246e-84	284.0	COG3000@1|root,COG3000@2|Bacteria,4NEYE@976|Bacteroidetes,1HWTG@117743|Flavobacteriia	976|Bacteroidetes	I	Sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
TLS3_k127_7115063_3	1453500.AT05_01575	1.67e-23	102.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	ko:K03972	-	-	-	-	ko00000	-	-	-	Rhodanese
TLS3_k127_7115063_0	1121889.AUDM01000005_gene1679	2.47e-179	576.0	COG2885@1|root,COG2885@2|Bacteria,4PPGM@976|Bacteroidetes,1IKM9@117743|Flavobacteriia,2P0S3@237|Flavobacterium	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7115063_1	984262.SGRA_2738	2.109e-156	511.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4842,PEGA
TLS3_k127_7115063_4	1313421.JHBV01000029_gene2023	3.976e-22	107.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	ko:K09942,ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Peptidase_S74,YadA_head,YadA_stalk
TLS3_k127_7115063_5	1384054.N790_01945	2.234e-07	52.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1X4MI@135614|Xanthomonadales	135614|Xanthomonadales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
TLS3_k127_7152488_2	755732.Fluta_2307	7.014e-77	263.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia,2PABJ@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Response regulator receiver domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_7152488_1	1408433.JHXV01000007_gene2855	3.644e-94	325.0	COG3291@1|root,COG3291@2|Bacteria,4PKU5@976|Bacteroidetes,1IJEZ@117743|Flavobacteriia,2PB2S@246874|Cryomorphaceae	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7152488_0	555500.I215_07237	4.147e-167	556.0	COG1629@1|root,COG1629@2|Bacteria,4PKRK@976|Bacteroidetes,1IJDQ@117743|Flavobacteriia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
TLS3_k127_7158780_2	313606.M23134_01137	0.0005003	45.0	COG0668@1|root,COG0668@2|Bacteria,4NHU7@976|Bacteroidetes,47P5J@768503|Cytophagia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
TLS3_k127_7158780_1	1408433.JHXV01000010_gene499	7.289e-104	347.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,1HX46@117743|Flavobacteriia,2PBB3@246874|Cryomorphaceae	976|Bacteroidetes	M	Peptidase family M23	mepM_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_7158780_0	755732.Fluta_0205	0.0	1081.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,1HWQ0@117743|Flavobacteriia,2PAMM@246874|Cryomorphaceae	976|Bacteroidetes	O	Hsp70 protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
TLS3_k127_71657_0	755732.Fluta_2208	1.023e-181	580.0	COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,1HXSX@117743|Flavobacteriia,2PAIJ@246874|Cryomorphaceae	976|Bacteroidetes	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
TLS3_k127_71657_4	755732.Fluta_2207	1.479e-30	125.0	2A9I2@1|root,30YQD@2|Bacteria,4PCM2@976|Bacteroidetes,1IMSU@117743|Flavobacteriia,2PC1C@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_71657_1	755732.Fluta_2206	7.178e-121	394.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,1HWZ0@117743|Flavobacteriia,2PA8C@246874|Cryomorphaceae	976|Bacteroidetes	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
TLS3_k127_71657_3	485918.Cpin_6970	5.46e-39	150.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,1IS84@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
TLS3_k127_71657_2	755732.Fluta_0297	1.107e-83	287.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,1HYA2@117743|Flavobacteriia,2PB1H@246874|Cryomorphaceae	976|Bacteroidetes	EG	EamA-like transporter family	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_7174293_3	755732.Fluta_0879	2.011e-48	176.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,1HXMK@117743|Flavobacteriia,2PAP4@246874|Cryomorphaceae	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
TLS3_k127_7174293_2	755732.Fluta_0878	1.284e-63	224.0	COG3091@1|root,COG3091@2|Bacteria,4NDXX@976|Bacteroidetes,1HZK2@117743|Flavobacteriia,2PB1I@246874|Cryomorphaceae	976|Bacteroidetes	S	protein conserved in bacteria	sprT	-	-	-	-	-	-	-	-	-	-	-	SprT-like
TLS3_k127_7174293_1	755732.Fluta_0877	2.342e-137	445.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,1HXFU@117743|Flavobacteriia,2PABQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Nucleotidyl transferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
TLS3_k127_7174293_4	755732.Fluta_0876	3.633e-46	177.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
TLS3_k127_7174293_0	755732.Fluta_0838	2.393e-150	479.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,1HWU7@117743|Flavobacteriia,2PAMB@246874|Cryomorphaceae	976|Bacteroidetes	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
TLS3_k127_7174293_5	269798.CHU_2040	3.771e-05	48.0	COG3509@1|root,COG3509@2|Bacteria,4NVPN@976|Bacteroidetes	976|Bacteroidetes	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase_phd
TLS3_k127_7216453_2	491205.JARQ01000008_gene3889	2.771e-08	59.0	COG1409@1|root,COG5337@1|root,COG1409@2|Bacteria,COG5337@2|Bacteria,4NVTX@976|Bacteroidetes	976|Bacteroidetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Fn3_assoc
TLS3_k127_7216453_1	1123037.AUDE01000027_gene2077	3.812e-37	160.0	COG5295@1|root,COG5295@2|Bacteria,4NV9S@976|Bacteroidetes,1IIJV@117743|Flavobacteriia	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
TLS3_k127_7216453_0	1313421.JHBV01000023_gene5167	5.628e-54	212.0	COG3210@1|root,COG5295@1|root,COG3210@2|Bacteria,COG5295@2|Bacteria,4PPRF@976|Bacteroidetes,1IZDI@117747|Sphingobacteriia	976|Bacteroidetes	U	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
TLS3_k127_7220363_0	755732.Fluta_3515	1.38e-220	697.0	COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes	976|Bacteroidetes	E	TIGRFAM oligoendopeptidase, M3 family	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
TLS3_k127_7220363_2	755732.Fluta_3514	2.45e-50	184.0	2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,1I1XW@117743|Flavobacteriia,2PB06@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7220363_1	755732.Fluta_3513	8.574e-111	374.0	COG1404@1|root,COG1404@2|Bacteria,4NTWX@976|Bacteroidetes,1I4GV@117743|Flavobacteriia,2PBAJ@246874|Cryomorphaceae	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_7222238_1	313603.FB2170_05535	9.552e-66	226.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,1HY8G@117743|Flavobacteriia,2PGZ1@252356|Maribacter	976|Bacteroidetes	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
TLS3_k127_7222238_0	755732.Fluta_1473	3.68e-74	257.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,1HXST@117743|Flavobacteriia,2PB5B@246874|Cryomorphaceae	976|Bacteroidetes	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TLS3_k127_7222238_2	755732.Fluta_1472	2.465e-31	126.0	COG0721@1|root,COG0721@2|Bacteria,4NV0A@976|Bacteroidetes,1IBR4@117743|Flavobacteriia,2PB5V@246874|Cryomorphaceae	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
TLS3_k127_7222238_3	1297742.A176_05043	9.039e-09	64.0	2DEY3@1|root,2ZPQN@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4476,SmpA_OmlA
TLS3_k127_7241212_2	755732.Fluta_1212	8.888e-48	181.0	COG1409@1|root,COG1409@2|Bacteria,4NGK2@976|Bacteroidetes,1I0BV@117743|Flavobacteriia	976|Bacteroidetes	M	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
TLS3_k127_7241212_1	755732.Fluta_1211	3.307e-110	375.0	2DTCX@1|root,33JRS@2|Bacteria,4NYXQ@976|Bacteroidetes,1I6V6@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7241212_0	755732.Fluta_1210	9.388e-175	567.0	COG3540@1|root,COG3540@2|Bacteria,4NH1W@976|Bacteroidetes,1HXGC@117743|Flavobacteriia,2PAGY@246874|Cryomorphaceae	976|Bacteroidetes	P	PhoD-like phosphatase, N-terminal domain	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
TLS3_k127_7260082_1	755732.Fluta_0847	1.184e-265	824.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1HXCJ@117743|Flavobacteriia,2PABT@246874|Cryomorphaceae	976|Bacteroidetes	L	RQC	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
TLS3_k127_7260082_4	755732.Fluta_0848	1.905e-103	344.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1HYNB@117743|Flavobacteriia,2PASC@246874|Cryomorphaceae	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
TLS3_k127_7260082_0	755732.Fluta_0849	0.0	1100.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,1IKD7@117743|Flavobacteriia,2PBJI@246874|Cryomorphaceae	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
TLS3_k127_7260082_3	755732.Fluta_0850	8.267e-125	404.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1HX61@117743|Flavobacteriia,2PAGD@246874|Cryomorphaceae	976|Bacteroidetes	S	ABC-type (Unclassified) transport system, ATPase component	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
TLS3_k127_7260082_2	755732.Fluta_0853	8.187e-136	451.0	COG4775@1|root,COG4775@2|Bacteria,4NF35@976|Bacteroidetes,1HZII@117743|Flavobacteriia,2PB09@246874|Cryomorphaceae	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA,ShlB
TLS3_k127_7260082_5	1121896.JMLU01000006_gene30	4.673e-49	183.0	COG4748@1|root,COG4748@2|Bacteria,4NDZX@976|Bacteroidetes,1HXGR@117743|Flavobacteriia,2NVKQ@237|Flavobacterium	976|Bacteroidetes	L	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	ko:K07504	-	-	-	-	ko00000	-	-	-	HSDR_N,HSDR_N_2
TLS3_k127_7263464_0	755732.Fluta_1867	0.0	1126.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,1HYR7@117743|Flavobacteriia,2PA7N@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
TLS3_k127_7263464_23	992406.RIA_0756	9.145e-15	76.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1I54R@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
TLS3_k127_7263464_3	1408433.JHXV01000007_gene2833	1.103e-204	646.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1HXBS@117743|Flavobacteriia,2PA8A@246874|Cryomorphaceae	976|Bacteroidetes	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
TLS3_k127_7263464_5	755732.Fluta_1465	6.127e-175	561.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,1HYXP@117743|Flavobacteriia,2PACQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Transglycosylase SLT domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
TLS3_k127_7263464_21	999419.HMPREF1077_00715	3.651e-18	96.0	COG0322@1|root,COG0322@2|Bacteria,4NGEV@976|Bacteroidetes,2FNVF@200643|Bacteroidia,22XZM@171551|Porphyromonadaceae	976|Bacteroidetes	L	Domain of unknown function (DUF4837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4837
TLS3_k127_7263464_9	755732.Fluta_1466	3.162e-91	308.0	COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,1HXFJ@117743|Flavobacteriia,2PB57@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
TLS3_k127_7263464_7	755732.Fluta_1467	6.703e-115	379.0	COG0859@1|root,COG0859@2|Bacteria,4NMIH@976|Bacteroidetes,1ICNI@117743|Flavobacteriia,2PBAY@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
TLS3_k127_7263464_19	391603.FBALC1_13697	6.087e-21	102.0	COG0382@1|root,COG0382@2|Bacteria,4NM5C@976|Bacteroidetes,1HWRB@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7263464_1	755732.Fluta_1501	3.263e-230	720.0	COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,1HY3T@117743|Flavobacteriia,2PAF3@246874|Cryomorphaceae	976|Bacteroidetes	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
TLS3_k127_7263464_18	1408433.JHXV01000001_gene1090	4.255e-23	105.0	COG2353@1|root,COG2353@2|Bacteria,4NUSB@976|Bacteroidetes,1I5NT@117743|Flavobacteriia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_7263464_12	111780.Sta7437_0449	3.407e-68	242.0	2DMDJ@1|root,32UGS@2|Bacteria,1GNV1@1117|Cyanobacteria,3VMC6@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7263464_22	634956.Geoth_1921	1.56e-15	84.0	COG1670@1|root,COG1670@2|Bacteria,1V4IY@1239|Firmicutes,4HG60@91061|Bacilli,1WHSE@129337|Geobacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	ykkB	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TLS3_k127_7263464_24	1122176.KB903556_gene4082	2.076e-10	72.0	COG2207@1|root,COG2207@2|Bacteria,4NUEG@976|Bacteroidetes	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_7263464_2	755732.Fluta_0606	1.472e-226	724.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,1I54C@117743|Flavobacteriia,2PAIC@246874|Cryomorphaceae	976|Bacteroidetes	Q	PFAM FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
TLS3_k127_7263464_16	755732.Fluta_4002	2.3e-37	145.0	COG4704@1|root,COG4704@2|Bacteria,4P9RE@976|Bacteroidetes,1ICNA@117743|Flavobacteriia,2PB7B@246874|Cryomorphaceae	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
TLS3_k127_7263464_26	504472.Slin_3657	0.0002561	51.0	2CA51@1|root,2ZR3W@2|Bacteria,4P852@976|Bacteroidetes,47X0U@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7263464_15	471854.Dfer_4854	7.131e-47	175.0	COG1595@1|root,COG1595@2|Bacteria,4NSVA@976|Bacteroidetes,47QAU@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_7263464_20	1408473.JHXO01000005_gene1451	3.78e-20	94.0	2E0NT@1|root,32W7U@2|Bacteria,4NTP9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7263464_10	755732.Fluta_2431	3.029e-82	279.0	COG1917@1|root,COG1917@2|Bacteria,4PMKQ@976|Bacteroidetes	976|Bacteroidetes	S	Aspartyl/Asparaginyl beta-hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Arg_Hydrox
TLS3_k127_7263464_14	991.IW20_15970	1.741e-48	179.0	2CSP1@1|root,32SRI@2|Bacteria,4NT1E@976|Bacteroidetes,1I3GB@117743|Flavobacteriia,2NW4N@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7263464_8	865937.Gilli_2180	6.4e-103	338.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,1HXG3@117743|Flavobacteriia,2P60E@244698|Gillisia	976|Bacteroidetes	P	Carbonic anhydrase	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
TLS3_k127_7263464_4	1313421.JHBV01000016_gene5495	5.518e-180	577.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes	976|Bacteroidetes	P	COGs COG0659 Sulfate permease and related transporter (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
TLS3_k127_7263464_11	313590.MED134_00985	6.123e-82	279.0	COG1309@1|root,COG1309@2|Bacteria,4NEUA@976|Bacteroidetes,1HZEU@117743|Flavobacteriia,37DF6@326319|Dokdonia	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_7263464_6	1178825.ALIH01000007_gene1742	4.399e-120	393.0	COG0861@1|root,COG0861@2|Bacteria,4NH7P@976|Bacteroidetes,1HZCI@117743|Flavobacteriia	976|Bacteroidetes	P	membrane protein TerC	alx	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
TLS3_k127_7263464_17	391587.KAOT1_08408	6.543e-25	114.0	2D4W4@1|root,32THR@2|Bacteria,4NU2F@976|Bacteroidetes,1I4YZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7263464_13	991.IW20_21690	1.228e-64	226.0	COG4278@1|root,COG4278@2|Bacteria,4NR5D@976|Bacteroidetes,1I30E@117743|Flavobacteriia,2NVN0@237|Flavobacterium	976|Bacteroidetes	H	phenylacetate-CoA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7263464_25	643867.Ftrac_0305	1.516e-08	66.0	COG3292@1|root,COG3920@1|root,COG3292@2|Bacteria,COG3920@2|Bacteria,4NKB1@976|Bacteroidetes,47UBV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_2,Reg_prop,Y_Y_Y
TLS3_k127_7278250_1	1296415.JACC01000011_gene533	8.477e-45	177.0	COG4942@1|root,COG4942@2|Bacteria,4NMI2@976|Bacteroidetes,1II5I@117743|Flavobacteriia,2YM4U@290174|Aquimarina	976|Bacteroidetes	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7278250_2	1443665.JACA01000013_gene4223	7.324e-23	106.0	2BTH3@1|root,32NPF@2|Bacteria,4P9SW@976|Bacteroidetes,1ICEN@117743|Flavobacteriia,2YKXQ@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7278250_0	391587.KAOT1_07328	3.404e-61	232.0	COG1752@1|root,COG1752@2|Bacteria,4NIDR@976|Bacteroidetes,1IJVI@117743|Flavobacteriia	976|Bacteroidetes	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
TLS3_k127_7279084_1	857087.Metme_2496	9.006e-06	55.0	28T3T@1|root,2ZFCV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7279084_0	215803.DB30_5512	1.595e-09	69.0	COG0455@1|root,COG2319@1|root,COG5635@1|root,COG0455@2|Bacteria,COG2319@2|Bacteria,COG5635@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YU5N@29|Myxococcales	28221|Deltaproteobacteria	T	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,WD40
TLS3_k127_728053_0	1408433.JHXV01000021_gene1681	3.291e-192	617.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,1HWU3@117743|Flavobacteriia,2PAE4@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase and permease	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
TLS3_k127_728053_3	1408433.JHXV01000021_gene1639	3.885e-30	122.0	2ASD9@1|root,31HSR@2|Bacteria,4NQ71@976|Bacteroidetes,1I2S7@117743|Flavobacteriia,2PB2W@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF3276)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3276
TLS3_k127_728053_1	755732.Fluta_3572	8.783e-154	487.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1HXYG@117743|Flavobacteriia,2PAED@246874|Cryomorphaceae	976|Bacteroidetes	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
TLS3_k127_728053_2	1408433.JHXV01000010_gene615	6.009e-71	243.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,1HXJD@117743|Flavobacteriia,2PAB0@246874|Cryomorphaceae	976|Bacteroidetes	K	ParB-like nuclease domain	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
TLS3_k127_7287610_4	1089547.KB913013_gene3467	7.163e-27	117.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,47KHB@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated lipoprotein GldK	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TLS3_k127_7287610_2	1408433.JHXV01000001_gene926	7.837e-95	322.0	COG0726@1|root,COG0726@2|Bacteria,4NQKC@976|Bacteroidetes,1I8X4@117743|Flavobacteriia,2PB6V@246874|Cryomorphaceae	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7287610_1	755732.Fluta_2332	4.156e-112	375.0	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,1HWZ7@117743|Flavobacteriia,2PB5P@246874|Cryomorphaceae	976|Bacteroidetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
TLS3_k127_7287610_0	755732.Fluta_2331	9.631e-151	485.0	COG2876@1|root,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1HX6I@117743|Flavobacteriia,2PAIH@246874|Cryomorphaceae	976|Bacteroidetes	E	Chorismate mutase type II	aroF	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
TLS3_k127_7287610_3	755732.Fluta_2329	4.366e-71	246.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,1HYB1@117743|Flavobacteriia,2PAXA@246874|Cryomorphaceae	976|Bacteroidetes	O	Glycoprotease family	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
TLS3_k127_7287610_5	1408433.JHXV01000024_gene1478	3.342e-21	93.0	COG0745@1|root,COG0745@2|Bacteria,4NM5Q@976|Bacteroidetes,1I1SA@117743|Flavobacteriia,2PBHX@246874|Cryomorphaceae	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_7293018_0	1121898.Q766_16355	1.555e-45	173.0	2E134@1|root,314GP@2|Bacteria,4NR5I@976|Bacteroidetes,1I64S@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7293018_2	1120966.AUBU01000002_gene2216	5.617e-26	120.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,47R74@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF393	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
TLS3_k127_7293018_1	511680.BUTYVIB_02094	3.238e-37	147.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	1.1.1.271,5.1.3.2,6.3.5.5	ko:K01784,ko:K01955,ko:K02377	ko00051,ko00052,ko00240,ko00250,ko00520,ko01100,map00051,map00052,map00240,map00250,map00520,map01100	M00051,M00361,M00362,M00632	R00256,R00291,R00575,R01395,R02984,R05692,R10948,R10949	RC00002,RC00010,RC00043,RC00289,RC01014,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
TLS3_k127_7308941_1	468059.AUHA01000004_gene2336	1.089e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,4NFMG@976|Bacteroidetes,1IRNU@117747|Sphingobacteriia	976|Bacteroidetes	S	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_10,TPR_12,TPR_19,TPR_7,TPR_8
TLS3_k127_7308941_0	1227739.Hsw_1402	1.454e-46	184.0	COG1520@1|root,COG3420@1|root,COG1520@2|Bacteria,COG3420@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
TLS3_k127_732851_0	398767.Glov_0093	5.447e-78	275.0	COG3177@1|root,COG3177@2|Bacteria,1NB0K@1224|Proteobacteria,42QY1@68525|delta/epsilon subdivisions,2WMXE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM filamentation induced by cAMP protein Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
TLS3_k127_7358180_1	1094466.KQS_05525	3.617e-240	802.0	COG1357@1|root,COG2374@1|root,COG3209@1|root,COG1357@2|Bacteria,COG2374@2|Bacteria,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,2NSCF@237|Flavobacterium	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,SprB
TLS3_k127_7358180_5	1408433.JHXV01000010_gene554	2.437e-71	277.0	COG2374@1|root,COG3209@1|root,COG4935@1|root,COG2374@2|Bacteria,COG3209@2|Bacteria,COG4935@2|Bacteria,4NT6S@976|Bacteroidetes,1I4XN@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,SprB
TLS3_k127_7358180_12	1121899.Q764_14500	1.583e-17	99.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SdrD_B,VWA,VWA_2
TLS3_k127_7358180_6	929556.Solca_3497	1.494e-60	241.0	COG1470@1|root,COG1520@1|root,COG1470@2|Bacteria,COG1520@2|Bacteria,4PN7K@976|Bacteroidetes	976|Bacteroidetes	L	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SprB
TLS3_k127_7358180_10	1408433.JHXV01000025_gene4027	1.536e-30	142.0	COG1520@1|root,COG5306@1|root,COG1520@2|Bacteria,COG5306@2|Bacteria,4NNUN@976|Bacteroidetes,1IKHC@117743|Flavobacteriia,2PBKQ@246874|Cryomorphaceae	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,SBBP
TLS3_k127_7358180_4	153721.MYP_2649	6.515e-148	477.0	COG1672@1|root,COG1672@2|Bacteria,4NGM3@976|Bacteroidetes,47VKT@768503|Cytophagia	976|Bacteroidetes	S	ATPase (AAA superfamily)	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2
TLS3_k127_7358180_0	755732.Fluta_2278	7.181e-293	905.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1HX8K@117743|Flavobacteriia,2PAEK@246874|Cryomorphaceae	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
TLS3_k127_7358180_8	755732.Fluta_2279	1.769e-42	157.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,1I3WW@117743|Flavobacteriia,2PB2J@246874|Cryomorphaceae	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
TLS3_k127_7358180_11	755732.Fluta_2280	1.018e-23	106.0	COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,1I418@117743|Flavobacteriia,2PB96@246874|Cryomorphaceae	976|Bacteroidetes	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
TLS3_k127_7358180_9	755732.Fluta_2281	2.73e-40	164.0	2ABIA@1|root,310ZH@2|Bacteria,4PFMS@976|Bacteroidetes,1ICAQ@117743|Flavobacteriia,2PB8S@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7358180_7	755732.Fluta_2282	3.097e-43	163.0	2CADI@1|root,315ID@2|Bacteria,4PJQG@976|Bacteroidetes,1IGJ9@117743|Flavobacteriia,2PB9D@246874|Cryomorphaceae	976|Bacteroidetes	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
TLS3_k127_7358180_3	755732.Fluta_2283	6.628e-190	600.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,1HXHS@117743|Flavobacteriia,2PAKE@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Bacterial regulatory protein, Fis family	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
TLS3_k127_7358180_2	755732.Fluta_2284	8.374e-221	692.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1HX6T@117743|Flavobacteriia,2PAFK@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
TLS3_k127_7368211_4	755732.Fluta_0034	1.886e-66	233.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1HYEQ@117743|Flavobacteriia,2PB11@246874|Cryomorphaceae	976|Bacteroidetes	M	TIGRFAM Outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
TLS3_k127_7368211_0	755732.Fluta_0036	3.678e-114	377.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,4NGHH@976|Bacteroidetes,1HZ6D@117743|Flavobacteriia,2PBE5@246874|Cryomorphaceae	976|Bacteroidetes	M	Lysin motif	mepM_1	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
TLS3_k127_7368211_2	755732.Fluta_0037	1.03e-76	265.0	COG0545@1|root,COG0545@2|Bacteria,4PHSB@976|Bacteroidetes,1ICRQ@117743|Flavobacteriia,2PBX1@246874|Cryomorphaceae	976|Bacteroidetes	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
TLS3_k127_7368211_5	1408433.JHXV01000010_gene505	1.748e-36	144.0	COG0545@1|root,COG0545@2|Bacteria,4NV96@976|Bacteroidetes,1IC47@117743|Flavobacteriia,2PB8G@246874|Cryomorphaceae	976|Bacteroidetes	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
TLS3_k127_7368211_1	153721.MYP_3615	5.544e-99	333.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,47MA7@768503|Cytophagia	976|Bacteroidetes	S	DHH family	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
TLS3_k127_7368211_3	755732.Fluta_0042	1.95e-71	245.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1HXYS@117743|Flavobacteriia,2PA4W@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
TLS3_k127_7383688_0	755732.Fluta_3584	4.303e-71	252.0	COG3842@1|root,COG3842@2|Bacteria,4NEZ6@976|Bacteroidetes,1HXA2@117743|Flavobacteriia,2PAZH@246874|Cryomorphaceae	976|Bacteroidetes	E	ATPases associated with a variety of cellular activities	fbpC2	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
TLS3_k127_7383688_1	755732.Fluta_3583	5.227e-68	242.0	COG1295@1|root,COG1295@2|Bacteria,4NFG8@976|Bacteroidetes,1HX47@117743|Flavobacteriia	976|Bacteroidetes	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
TLS3_k127_7410722_3	886379.AEWI01000014_gene1419	7.145e-26	111.0	COG1629@1|root,COG1629@2|Bacteria,4PKRK@976|Bacteroidetes,2G0D1@200643|Bacteroidia,3XIXP@558415|Marinilabiliaceae	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_7410722_1	755732.Fluta_2327	2.101e-91	305.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia,2PABJ@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Response regulator receiver domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_7410722_0	1408433.JHXV01000007_gene2820	7.157e-222	709.0	COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes,1HYFK@117743|Flavobacteriia,2PBGW@246874|Cryomorphaceae	976|Bacteroidetes	P	PhoU domain	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
TLS3_k127_7410722_2	755732.Fluta_2328	1.266e-65	230.0	COG0745@1|root,COG0745@2|Bacteria,4NM5Q@976|Bacteroidetes,1I1SA@117743|Flavobacteriia,2PBHX@246874|Cryomorphaceae	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_746897_2	1408433.JHXV01000025_gene4020	5.388e-43	179.0	COG4928@1|root,COG4928@2|Bacteria	2|Bacteria	G	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	KAP_NTPase,WD40
TLS3_k127_746897_0	1408433.JHXV01000033_gene1171	8.114e-257	801.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1HYVB@117743|Flavobacteriia,2PABD@246874|Cryomorphaceae	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
TLS3_k127_746897_1	1408433.JHXV01000033_gene1172	1.29e-225	716.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,1HX7T@117743|Flavobacteriia,2PAB2@246874|Cryomorphaceae	976|Bacteroidetes	G	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TLS3_k127_7492660_4	755732.Fluta_1063	4.05e-26	112.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1HXXP@117743|Flavobacteriia,2PB0R@246874|Cryomorphaceae	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7492660_3	755732.Fluta_1062	5.832e-47	178.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,1I1AK@117743|Flavobacteriia,2PB1F@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
TLS3_k127_7492660_6	1484460.JSWG01000009_gene584	5.869e-05	48.0	2DR32@1|root,339YJ@2|Bacteria,4NYM3@976|Bacteroidetes,1I6CH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7492660_2	945713.IALB_2577	3.466e-138	456.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,HYR,LTD,P_proprotein
TLS3_k127_7492660_1	45351.EDO25701	3.711e-170	538.0	COG0646@1|root,KOG1579@2759|Eukaryota,38H40@33154|Opisthokonta,3BHBF@33208|Metazoa	33208|Metazoa	E	5-methyltetrahydrofolate-dependent methyltransferase activity	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
TLS3_k127_7492660_0	755732.Fluta_1068	0.0	1233.0	COG1410@1|root,COG1410@2|Bacteria,4PKI8@976|Bacteroidetes,1HXB5@117743|Flavobacteriia,2PAI8@246874|Cryomorphaceae	976|Bacteroidetes	H	Vitamin B12 dependent methionine synthase, activation domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,DUF559,Met_synt_B12,Pterin_bind
TLS3_k127_7504622_1	755732.Fluta_2928	2.103e-19	91.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,1HXKN@117743|Flavobacteriia,2PAPV@246874|Cryomorphaceae	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
TLS3_k127_7504622_0	755732.Fluta_2927	1.585e-136	444.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1HWSR@117743|Flavobacteriia,2PADJ@246874|Cryomorphaceae	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
TLS3_k127_7504622_2	755732.Fluta_3336	8.102e-11	63.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2PBEH@246874|Cryomorphaceae	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
TLS3_k127_7508059_1	755732.Fluta_0653	1.557e-125	405.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,1HY7R@117743|Flavobacteriia,2PAT4@246874|Cryomorphaceae	976|Bacteroidetes	L	Endonuclease/Exonuclease/phosphatase family	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
TLS3_k127_7508059_0	1313421.JHBV01000041_gene3455	1.087e-166	532.0	COG1741@1|root,COG1741@2|Bacteria,4NFZD@976|Bacteroidetes,1IPEQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
TLS3_k127_7508059_2	5875.XP_766720.1	1.199e-09	68.0	2CMYA@1|root,2QSQ7@2759|Eukaryota,3YBWW@5794|Apicomplexa,3KB8N@422676|Aconoidasida,3Z4N8@5863|Piroplasmida	422676|Aconoidasida	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.4.12	ko:K01117	ko00600,ko01100,map00600,map01100	-	R02541	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	Exo_endo_phos
TLS3_k127_7511895_0	755732.Fluta_2750	5.304e-163	521.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1HYRP@117743|Flavobacteriia,2PBBJ@246874|Cryomorphaceae	976|Bacteroidetes	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
TLS3_k127_7511895_1	755732.Fluta_2721	2.335e-71	250.0	COG2242@1|root,COG2242@2|Bacteria,4NXTG@976|Bacteroidetes	976|Bacteroidetes	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
TLS3_k127_7511895_2	755732.Fluta_2719	4.517e-53	188.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,1HXV7@117743|Flavobacteriia,2PAJB@246874|Cryomorphaceae	976|Bacteroidetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_7512829_1	755732.Fluta_1546	7.402e-46	167.0	COG3279@1|root,COG3279@2|Bacteria,4NKXC@976|Bacteroidetes,1I0BK@117743|Flavobacteriia,2PAUQ@246874|Cryomorphaceae	976|Bacteroidetes	K	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_7512829_0	755732.Fluta_1552	8.314e-285	891.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1HWPN@117743|Flavobacteriia,2PA9G@246874|Cryomorphaceae	976|Bacteroidetes	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
TLS3_k127_7512829_2	755732.Fluta_1554	7.001e-17	81.0	COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,1HY16@117743|Flavobacteriia,2PAVC@246874|Cryomorphaceae	976|Bacteroidetes	C	Ferritin-like domain	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
TLS3_k127_7528851_4	926562.Oweho_1685	1.368e-10	63.0	COG0612@1|root,COG0612@2|Bacteria,4NEE4@976|Bacteroidetes,1I83S@117743|Flavobacteriia,2PBJ4@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_7528851_2	755732.Fluta_3987	4.659e-61	217.0	COG0259@1|root,COG0259@2|Bacteria,4NFH7@976|Bacteroidetes,1HXWH@117743|Flavobacteriia,2PAXJ@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
TLS3_k127_7528851_1	755732.Fluta_3988	1.194e-65	230.0	2985A@1|root,2ZVB7@2|Bacteria,4NNTB@976|Bacteroidetes,1I0QR@117743|Flavobacteriia,2PBR8@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4494)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4494
TLS3_k127_7528851_0	755732.Fluta_3989	3.317e-90	308.0	2ABBW@1|root,310SM@2|Bacteria,4PFE8@976|Bacteroidetes,1IG1J@117743|Flavobacteriia,2PBZZ@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7528851_3	626523.GCWU000342_00322	4.013e-13	72.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	ydaS	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
TLS3_k127_7534805_0	755732.Fluta_0051	6.985e-251	777.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,1HWNU@117743|Flavobacteriia,2PAEM@246874|Cryomorphaceae	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
TLS3_k127_7534805_6	755732.Fluta_0050	3.154e-61	216.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1HY1W@117743|Flavobacteriia,2PBV2@246874|Cryomorphaceae	976|Bacteroidetes	CO	PFAM AhpC TSA family	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
TLS3_k127_7534805_5	755732.Fluta_1995	2.712e-61	228.0	COG2319@1|root,COG2319@2|Bacteria,4NNKN@976|Bacteroidetes,1IMSD@117743|Flavobacteriia,2PBXF@246874|Cryomorphaceae	976|Bacteroidetes	S	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7534805_8	1408433.JHXV01000005_gene2290	4.074e-10	74.0	COG1729@1|root,COG1729@2|Bacteria,4PMDU@976|Bacteroidetes,1IKE6@117743|Flavobacteriia,2PB2R@246874|Cryomorphaceae	976|Bacteroidetes	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
TLS3_k127_7534805_7	755732.Fluta_0236	3.169e-53	194.0	COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,1I181@117743|Flavobacteriia,2PAYH@246874|Cryomorphaceae	976|Bacteroidetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
TLS3_k127_7534805_1	755732.Fluta_0235	6.572e-194	609.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,1HXKY@117743|Flavobacteriia,2PAIS@246874|Cryomorphaceae	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
TLS3_k127_7534805_4	1349785.BAUG01000031_gene1825	8.864e-71	249.0	COG1266@1|root,COG1266@2|Bacteria,4NFKV@976|Bacteroidetes,1HY21@117743|Flavobacteriia	976|Bacteroidetes	S	CAAX amino terminal protease family	yyaK	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
TLS3_k127_7534805_2	925409.KI911562_gene2750	4.068e-151	485.0	COG0535@1|root,COG0535@2|Bacteria,4NFRX@976|Bacteroidetes,1IPEG@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
TLS3_k127_7534805_3	926549.KI421517_gene3687	5.097e-105	343.0	COG0500@1|root,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,47MZ1@768503|Cytophagia	976|Bacteroidetes	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
TLS3_k127_7538599_1	1233951.IO90_14330	3.762e-110	360.0	COG4529@1|root,COG4529@2|Bacteria,4NFKU@976|Bacteroidetes,1HZPU@117743|Flavobacteriia	976|Bacteroidetes	S	FAD-NAD(P)-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_9
TLS3_k127_7538599_2	192952.MM_0889	2.56e-64	239.0	arCOG02349@1|root,arCOG03567@1|root,arCOG02349@2157|Archaea,arCOG03567@2157|Archaea,2Y7N7@28890|Euryarchaeota,2NBKF@224756|Methanomicrobia	224756|Methanomicrobia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,PAS_3
TLS3_k127_7538599_3	755732.Fluta_3341	1.203e-61	235.0	COG1470@1|root,COG3386@1|root,COG1470@2|Bacteria,COG3386@2|Bacteria,4PM1B@976|Bacteroidetes,1IKE7@117743|Flavobacteriia,2PC6R@246874|Cryomorphaceae	2|Bacteria	G	SPTR Cell surface protein	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	ASH,BNR_2,NPCBM_assoc,PEGA
TLS3_k127_7538599_5	45351.EDO31271	4.422e-25	121.0	2BU84@1|root,2S22P@2759|Eukaryota	2759|Eukaryota	S	odorant binding	LCN1	GO:0003008,GO:0003674,GO:0004857,GO:0004866,GO:0004869,GO:0005102,GO:0005488,GO:0005515,GO:0005549,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0007600,GO:0007606,GO:0007608,GO:0007610,GO:0007635,GO:0008150,GO:0008152,GO:0008270,GO:0009892,GO:0010466,GO:0010605,GO:0010876,GO:0010951,GO:0015711,GO:0015718,GO:0015849,GO:0015908,GO:0015909,GO:0019222,GO:0019538,GO:0030162,GO:0030234,GO:0030414,GO:0031323,GO:0031324,GO:0031404,GO:0032268,GO:0032269,GO:0032501,GO:0033036,GO:0042221,GO:0042802,GO:0042803,GO:0043086,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043621,GO:0044092,GO:0044238,GO:0044421,GO:0045861,GO:0046872,GO:0046914,GO:0046942,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050877,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0071702,GO:0071704,GO:0080090,GO:0098772,GO:1901564	-	-	-	-	-	-	-	-	-	-	Lipocalin
TLS3_k127_7538599_0	487796.Flav2ADRAFT_0733	1.287e-264	826.0	COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,1HWRN@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter, transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
TLS3_k127_7538599_6	335543.Sfum_1633	5.926e-12	78.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1570,LRR_4,LRR_5
TLS3_k127_7538599_4	376686.Fjoh_3165	2.057e-25	123.0	COG3064@1|root,COG3064@2|Bacteria,4NS7W@976|Bacteroidetes,1IJ56@117743|Flavobacteriia,2NT0N@237|Flavobacterium	976|Bacteroidetes	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
TLS3_k127_7552777_1	314230.DSM3645_05505	7.265e-18	86.0	COG2378@1|root,COG2378@2|Bacteria,2IY2R@203682|Planctomycetes	203682|Planctomycetes	K	Transcriptional regulator	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
TLS3_k127_7552777_0	1296416.JACB01000005_gene205	9.666e-74	258.0	2AT7P@1|root,31IQG@2|Bacteria,4NQMM@976|Bacteroidetes,1I4MP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7552777_3	714943.Mucpa_1966	1.47e-06	61.0	COG0793@1|root,COG0793@2|Bacteria,4NN0C@976|Bacteroidetes	976|Bacteroidetes	M	peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
TLS3_k127_7552777_2	1408473.JHXO01000003_gene2586	7.797e-11	72.0	2DRHS@1|root,33BTF@2|Bacteria,4NXHD@976|Bacteroidetes,2FXQ0@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7572226_11	755732.Fluta_1569	1.339e-106	351.0	COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,1HXT9@117743|Flavobacteriia,2PAAR@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Peptidase C1-like family	pepC	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1,Peptidase_C1_2
TLS3_k127_7572226_23	391587.KAOT1_09231	3.559e-21	104.0	COG2885@1|root,COG2885@2|Bacteria,4NHRP@976|Bacteroidetes,1HXVY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
TLS3_k127_7572226_24	1279009.ADICEAN_03553	1.38e-15	78.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,47S4A@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
TLS3_k127_7572226_5	1288963.ADIS_0074	6.245e-170	541.0	COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,47K0A@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
TLS3_k127_7572226_17	755732.Fluta_1612	2.477e-46	171.0	295MU@1|root,32PV8@2|Bacteria,4PB2D@976|Bacteroidetes,1IEBK@117743|Flavobacteriia,2PC5V@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7572226_16	755732.Fluta_1610	2.239e-56	203.0	COG0666@1|root,COG0666@2|Bacteria,4PJ3E@976|Bacteroidetes,1ICSZ@117743|Flavobacteriia,2PC1V@246874|Cryomorphaceae	976|Bacteroidetes	S	Suppressor of fused protein (SUFU)	-	-	-	-	-	-	-	-	-	-	-	-	SUFU
TLS3_k127_7572226_6	755732.Fluta_1913	7.479e-162	514.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,1HYS3@117743|Flavobacteriia,2PAC1@246874|Cryomorphaceae	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
TLS3_k127_7572226_1	755732.Fluta_1911	2.959e-282	891.0	COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,1I8HX@117743|Flavobacteriia,2PAB4@246874|Cryomorphaceae	976|Bacteroidetes	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
TLS3_k127_7572226_21	399739.Pmen_4463	1.043e-26	123.0	2CBZJ@1|root,32SMA@2|Bacteria,1N4V2@1224|Proteobacteria,1SBW2@1236|Gammaproteobacteria,1YIVV@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3298
TLS3_k127_7572226_25	1048983.EL17_13260	1.421e-11	71.0	2DM4T@1|root,31QCU@2|Bacteria,4PK44@976|Bacteroidetes,47QH5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7572226_10	755732.Fluta_1872	6.445e-109	367.0	2C5X1@1|root,2Z7M9@2|Bacteria,4NG0H@976|Bacteroidetes,1HWUD@117743|Flavobacteriia	976|Bacteroidetes	S	LETM1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LETM1
TLS3_k127_7572226_13	1239415.CM001837_gene2885	2.92e-86	304.0	COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,1HYKJ@117743|Flavobacteriia,37E4G@326319|Dokdonia	976|Bacteroidetes	O	Subtilase family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
TLS3_k127_7572226_14	742726.HMPREF9448_00670	1.355e-79	278.0	COG0438@1|root,COG0438@2|Bacteria,4NFMB@976|Bacteroidetes,2FMJE@200643|Bacteroidia,22XBH@171551|Porphyromonadaceae	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
TLS3_k127_7572226_9	755732.Fluta_1591	6.429e-117	387.0	COG0438@1|root,COG0438@2|Bacteria,4NH7K@976|Bacteroidetes,1I0D7@117743|Flavobacteriia,2PAGP@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_7572226_0	313598.MED152_10740	0.0	1253.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1HWS4@117743|Flavobacteriia,3VVC7@52959|Polaribacter	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
TLS3_k127_7572226_7	755732.Fluta_1559	1.63e-161	516.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,1HX4M@117743|Flavobacteriia,2PA6Q@246874|Cryomorphaceae	976|Bacteroidetes	G	Fructose-1-6-bisphosphatase, N-terminal domain	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
TLS3_k127_7572226_22	1282356.H045_09285	1.574e-25	111.0	COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,1S69A@1236|Gammaproteobacteria,1YTPT@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	SNARE associated Golgi protein	yqaA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
TLS3_k127_7572226_19	1408433.JHXV01000019_gene1974	1.325e-28	133.0	COG4677@1|root,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	-	-	3.2.1.51,4.2.2.23	ko:K10297,ko:K15923,ko:K18197	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04121	-	GH95,PL11	-	Beta_helix,CBM_35,Glyco_hydro_98M
TLS3_k127_7572226_15	755732.Fluta_1616	1.704e-79	273.0	COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,1HXV8@117743|Flavobacteriia,2PAWR@246874|Cryomorphaceae	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	yafV	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
TLS3_k127_7572226_8	1229487.AMYW01000045_gene2636	1.488e-145	470.0	COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,1HWQ8@117743|Flavobacteriia,2NSGV@237|Flavobacterium	976|Bacteroidetes	E	Class I and II	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_7572226_3	755732.Fluta_1604	2.95e-212	668.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1HWQS@117743|Flavobacteriia,2PAE8@246874|Cryomorphaceae	976|Bacteroidetes	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS3_k127_7572226_4	755732.Fluta_1605	8.569e-203	638.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1HWY8@117743|Flavobacteriia,2PAF8@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
TLS3_k127_7572226_2	1408433.JHXV01000011_gene2000	2.128e-215	677.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,1HXAE@117743|Flavobacteriia,2PA4J@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid	kmo	-	1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
TLS3_k127_7572226_20	1408433.JHXV01000011_gene1999	3.062e-27	123.0	2BV66@1|root,32QJI@2|Bacteria,4PC9C@976|Bacteroidetes,1ICSX@117743|Flavobacteriia,2PC1F@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7572226_18	755732.Fluta_1609	4.253e-38	145.0	COG1393@1|root,COG1393@2|Bacteria,4NSAW@976|Bacteroidetes,1I450@117743|Flavobacteriia,2PB6E@246874|Cryomorphaceae	976|Bacteroidetes	P	ArsC family	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
TLS3_k127_7572226_12	755732.Fluta_2348	4.337e-103	358.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF4082,DUF4347,HemolysinCabind,SprB
TLS3_k127_7588403_1	269798.CHU_0947	3.301e-22	98.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,47JNP@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
TLS3_k127_7588403_3	7739.XP_002605584.1	2.03e-11	72.0	COG4886@1|root,KOG0619@2759|Eukaryota	2759|Eukaryota	U	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8
TLS3_k127_7588403_2	1469557.JSWF01000036_gene808	6.493e-21	106.0	COG3209@1|root,COG3291@1|root,COG3897@1|root,COG4886@1|root,COG5306@1|root,COG5492@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3897@2|Bacteria,COG4886@2|Bacteria,COG5306@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	htaA	-	3.4.21.72	ko:K01347,ko:K03561,ko:K12287	-	-	-	-	ko00000,ko01000,ko01002,ko02000,ko02044	1.A.30.2.1,1.B.12.3	-	-	CHU_C,DUF2341,HtaA,LRR_5,Laminin_G_3,MotA_ExbB
TLS3_k127_7588403_0	1408433.JHXV01000005_gene2317	7.31e-41	166.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1I0R3@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
TLS3_k127_7611140_1	269798.CHU_3514	1.949e-31	135.0	2C85E@1|root,335NV@2|Bacteria,4NVTV@976|Bacteroidetes,47S04@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PCMD
TLS3_k127_7611140_0	755732.Fluta_0140	2.751e-70	267.0	COG3210@1|root,COG3291@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337,ko:K13735,ko:K15125	ko05100,ko05133,map05100,map05133	-	-	-	ko00000,ko00001,ko00536,ko01000,ko01002	-	-	-	Big_3_2,CHU_C,Copper-bind,DUF1080,PKD
TLS3_k127_7636705_4	1123253.AUBD01000005_gene136	4.814e-14	81.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,1RMBX@1236|Gammaproteobacteria,1X3AE@135614|Xanthomonadales	135614|Xanthomonadales	F	Na dependent nucleoside transporter	yeiM	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
TLS3_k127_7636705_3	755732.Fluta_0842	5.02e-72	248.0	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,1HXCB@117743|Flavobacteriia,2PAS5@246874|Cryomorphaceae	976|Bacteroidetes	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
TLS3_k127_7636705_1	755732.Fluta_0841	1.021e-150	481.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1HX9P@117743|Flavobacteriia,2PAQ3@246874|Cryomorphaceae	976|Bacteroidetes	C	Electron transfer flavoprotein domain	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
TLS3_k127_7636705_2	755732.Fluta_0840	4.441e-127	412.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,1HX74@117743|Flavobacteriia,2PAQ1@246874|Cryomorphaceae	976|Bacteroidetes	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
TLS3_k127_7636705_0	755732.Fluta_0839	2.294e-191	599.0	COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,1HWQC@117743|Flavobacteriia,2PADS@246874|Cryomorphaceae	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
TLS3_k127_7636705_5	643867.Ftrac_2941	4.227e-06	56.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
TLS3_k127_7649803_0	743722.Sph21_1946	4.022e-73	270.0	COG1216@1|root,COG1216@2|Bacteria,4NKEM@976|Bacteroidetes,1IWXW@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_7649803_1	69042.WH5701_14151	1.261e-69	249.0	COG0438@1|root,COG0438@2|Bacteria,1G2T9@1117|Cyanobacteria,1GZPU@1129|Synechococcus	1117|Cyanobacteria	M	Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_7649803_2	56110.Oscil6304_6057	4.923e-26	121.0	COG0382@1|root,COG0500@1|root,COG1196@1|root,COG5285@1|root,COG0382@2|Bacteria,COG1196@2|Bacteria,COG2226@2|Bacteria,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	strG	-	2.1.1.163,2.1.1.201,2.5.1.133,2.5.1.62	ko:K03183,ko:K04040	ko00130,ko00860,ko01100,ko01110,map00130,map00860,map01100,map01110	M00116,M00117	R04990,R04993,R06284,R06859,R08774,R09067,R09736,R11514,R11517	RC00003,RC00020,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	Methyltransf_23,Methyltransf_25,PhyH,UbiA
TLS3_k127_767060_0	1408433.JHXV01000005_gene2361	1.362e-104	353.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1HY2Q@117743|Flavobacteriia,2PBZ4@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_3,Kelch_4,Kelch_6
TLS3_k127_767060_1	1408433.JHXV01000020_gene3539	1.124e-87	303.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1HY2Q@117743|Flavobacteriia,2PBZ4@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Kelch motif	nanM	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6
TLS3_k127_767060_5	984262.SGRA_1386	2.612e-13	81.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF1080,MAM,PKD,SprB,fn3
TLS3_k127_767060_2	1313421.JHBV01000015_gene5755	5.462e-35	148.0	COG0265@1|root,COG3209@1|root,COG3291@1|root,COG5337@1|root,COG0265@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.4.21.107,3.4.21.50	ko:K01337,ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Collagen,CotH,Fn3_assoc,LTD
TLS3_k127_767060_3	1120966.AUBU01000013_gene385	4.218e-20	91.0	2CB74@1|root,33E9Q@2|Bacteria,4NXAI@976|Bacteroidetes,47WE8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_767060_4	1045858.Bint_1894	7.229e-19	98.0	COG0666@1|root,COG0666@2|Bacteria,2J5FX@203691|Spirochaetes	203691|Spirochaetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4,Ank_5
TLS3_k127_7671832_0	1283300.ATXB01000002_gene2755	3.72e-281	914.0	COG2351@1|root,COG2351@2|Bacteria,1QWX0@1224|Proteobacteria,1T4J1@1236|Gammaproteobacteria,1XG68@135618|Methylococcales	135618|Methylococcales	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7676232_0	755732.Fluta_3902	2.432e-185	589.0	COG0823@1|root,COG2885@1|root,COG3063@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,COG3063@2|Bacteria,4NE6G@976|Bacteroidetes,1INKT@117743|Flavobacteriia,2PA4S@246874|Cryomorphaceae	976|Bacteroidetes	MNU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
TLS3_k127_7676232_2	1346330.M472_14490	9.914e-80	270.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1IQ8P@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
TLS3_k127_7676232_1	755732.Fluta_3900	1.607e-95	321.0	COG4292@1|root,COG4292@2|Bacteria	2|Bacteria	S	Bacterial low temperature requirement A protein (LtrA)	-	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK,LtrA
TLS3_k127_7676232_4	755732.Fluta_1487	1.502e-55	207.0	COG3291@1|root,COG3291@2|Bacteria,4NNHP@976|Bacteroidetes,1I21K@117743|Flavobacteriia	976|Bacteroidetes	U	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS,fn3
TLS3_k127_7676232_3	755732.Fluta_1488	6.106e-78	266.0	COG4206@1|root,COG4206@2|Bacteria,4NIJS@976|Bacteroidetes	976|Bacteroidetes	H	COG4206 Outer membrane cobalamin receptor protein	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_7696870_2	1235803.C825_02149	1.583e-66	241.0	COG1629@1|root,COG4771@2|Bacteria,4PMUZ@976|Bacteroidetes,2FMM0@200643|Bacteroidia,22ZTD@171551|Porphyromonadaceae	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_7696870_0	755732.Fluta_1720	4.933e-95	317.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,1HXV5@117743|Flavobacteriia,2PARG@246874|Cryomorphaceae	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	1.1.3.48,2.7.7.38	ko:K00979,ko:K19714	ko00540,ko01100,map00540,map01100	M00063	R03351,R11394,R11396	RC00152,RC00910,RC03427	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
TLS3_k127_7696870_1	755732.Fluta_1583	1.555e-83	291.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes,1IG37@117743|Flavobacteriia,2PB68@246874|Cryomorphaceae	976|Bacteroidetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
TLS3_k127_7696870_3	755732.Fluta_1569	1.409e-48	177.0	COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,1HXT9@117743|Flavobacteriia,2PAAR@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Peptidase C1-like family	pepC	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1,Peptidase_C1_2
TLS3_k127_7697484_0	1121889.AUDM01000008_gene767	7.236e-58	209.0	COG1345@1|root,COG1404@1|root,COG3291@1|root,COG1345@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,2NSFX@237|Flavobacterium	976|Bacteroidetes	N	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CUB,fn3
TLS3_k127_7697484_1	153721.MYP_2602	2.719e-14	87.0	COG1572@1|root,COG2931@1|root,COG3227@1|root,COG3266@1|root,COG3291@1|root,COG4447@1|root,COG4733@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3227@2|Bacteria,COG3266@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
TLS3_k127_7707034_1	755732.Fluta_3215	3.553e-121	396.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1HWSU@117743|Flavobacteriia,2PAFW@246874|Cryomorphaceae	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
TLS3_k127_7707034_0	755732.Fluta_3216	6.725e-155	493.0	COG1577@1|root,COG1577@2|Bacteria,4NDYJ@976|Bacteroidetes,1HX9R@117743|Flavobacteriia,2PBRE@246874|Cryomorphaceae	976|Bacteroidetes	H	PFAM GHMP kinases N terminal domain	mvaK	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
TLS3_k127_7707034_2	755732.Fluta_3217	5.991e-21	92.0	COG3407@1|root,COG3407@2|Bacteria,4NDYX@976|Bacteroidetes,1HY6U@117743|Flavobacteriia,2PBJZ@246874|Cryomorphaceae	976|Bacteroidetes	I	diphosphomevalonate decarboxylase	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	-
TLS3_k127_7727127_6	1313301.AUGC01000017_gene795	2.093e-58	206.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes	976|Bacteroidetes	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_7727127_1	1121898.Q766_12485	6.973e-121	391.0	COG0463@1|root,COG0463@2|Bacteria,4PKIQ@976|Bacteroidetes,1HZHQ@117743|Flavobacteriia,2NVH2@237|Flavobacterium	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_7727127_7	755732.Fluta_3653	1.864e-46	172.0	2A94Y@1|root,30Y99@2|Bacteria,4PC0Q@976|Bacteroidetes,1ICRR@117743|Flavobacteriia,2PBX3@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7727127_0	755732.Fluta_3652	1.453e-154	497.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,1HZPF@117743|Flavobacteriia,2PBBV@246874|Cryomorphaceae	976|Bacteroidetes	S	Nucleoside recognition	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
TLS3_k127_7727127_3	755732.Fluta_3650	3.587e-83	280.0	COG0009@1|root,COG0009@2|Bacteria,4NDZR@976|Bacteroidetes,1HX8T@117743|Flavobacteriia,2PASB@246874|Cryomorphaceae	976|Bacteroidetes	J	TIGRFAM Sua5 YciO YrdC YwlC family protein	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
TLS3_k127_7727127_2	755732.Fluta_3535	8.991e-118	389.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,1IJJS@117743|Flavobacteriia,2PAXM@246874|Cryomorphaceae	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_7727127_4	755732.Fluta_3534	2.298e-73	258.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,1HZIN@117743|Flavobacteriia,2PB02@246874|Cryomorphaceae	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TLS3_k127_7727127_5	755732.Fluta_3533	1.099e-60	218.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,1HX94@117743|Flavobacteriia,2PB1Z@246874|Cryomorphaceae	976|Bacteroidetes	S	Eukaryotic integral membrane protein (DUF1751)	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
TLS3_k127_7727127_8	755732.Fluta_3532	1.811e-35	144.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,1HWX8@117743|Flavobacteriia,2PAGM@246874|Cryomorphaceae	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
TLS3_k127_7738417_15	666684.AfiDRAFT_0881	8.382e-14	76.0	COG2203@1|root,COG3920@1|root,COG2203@2|Bacteria,COG3920@2|Bacteria,1N4N2@1224|Proteobacteria,2TUS3@28211|Alphaproteobacteria,3JWEF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA_2
TLS3_k127_7738417_9	1237149.C900_00069	1.034e-47	179.0	COG3279@1|root,COG3279@2|Bacteria,4NF8A@976|Bacteroidetes	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
TLS3_k127_7738417_16	926549.KI421517_gene29	2.439e-13	82.0	COG3391@1|root,COG3391@2|Bacteria,4NSPG@976|Bacteroidetes,47V9V@768503|Cytophagia	976|Bacteroidetes	O	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7738417_19	98439.AJLL01000075_gene878	5.173e-08	64.0	COG1657@1|root,COG1657@2|Bacteria,1G0MR@1117|Cyanobacteria,1JGTZ@1189|Stigonemataceae	1117|Cyanobacteria	I	Squalene-hopene cyclase N-terminal domain	shc	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
TLS3_k127_7738417_20	43989.cce_0241	1.368e-07	63.0	COG0382@1|root,COG0382@2|Bacteria,1G1UG@1117|Cyanobacteria,3KGI1@43988|Cyanothece	1117|Cyanobacteria	H	UbiA prenyltransferase	-	GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009987,GO:0010189,GO:0018130,GO:0042360,GO:0042362,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617	2.5.1.115,2.5.1.116	ko:K09833	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07500,R10708	RC01840,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iJN678.slr1736	UbiA
TLS3_k127_7738417_12	697282.Mettu_3753	6.335e-31	134.0	2DC1U@1|root,2ZCHV@2|Bacteria,1RAWF@1224|Proteobacteria,1SC4Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7738417_0	1123057.P872_15960	5.811e-285	898.0	COG3002@1|root,COG3002@2|Bacteria,4NECE@976|Bacteroidetes,47MDY@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
TLS3_k127_7738417_1	1288963.ADIS_2733	2.874e-228	722.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,47NRZ@768503|Cytophagia	976|Bacteroidetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
TLS3_k127_7738417_8	572480.Arnit_1778	4.342e-48	189.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2YNAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
TLS3_k127_7738417_5	1197477.IA57_10265	1.908e-58	207.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,1I1AR@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
TLS3_k127_7738417_4	945713.IALB_0478	8.989e-71	267.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PKD,Ricin_B_lectin
TLS3_k127_7738417_14	755732.Fluta_2066	5.339e-15	89.0	COG3291@1|root,COG3291@2|Bacteria,4P1A1@976|Bacteroidetes	976|Bacteroidetes	E	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7738417_17	1121373.KB903625_gene3214	3.254e-11	69.0	COG0526@1|root,COG0607@1|root,COG0526@2|Bacteria,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,47PJB@768503|Cytophagia	976|Bacteroidetes	OP	COGs COG0607 Rhodanese-related sulfurtransferase	glpE	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Thioredoxin
TLS3_k127_7738417_6	755732.Fluta_1713	9.941e-57	200.0	28NYH@1|root,2ZBVN@2|Bacteria,4NMB2@976|Bacteroidetes,1I177@117743|Flavobacteriia,2PAV7@246874|Cryomorphaceae	976|Bacteroidetes	S	Disulphide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
TLS3_k127_7738417_11	760192.Halhy_3936	2.637e-32	145.0	COG0457@1|root,COG0666@1|root,COG0457@2|Bacteria,COG0666@2|Bacteria,4NM6P@976|Bacteroidetes,1IXEU@117747|Sphingobacteriia	976|Bacteroidetes	S	Astacin (Peptidase family M12A)	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
TLS3_k127_7738417_10	760192.Halhy_3780	1.415e-42	178.0	COG4249@1|root,COG4249@2|Bacteria,4NS33@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Peptidase C14, caspase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
TLS3_k127_7738417_21	880071.Fleli_3258	0.0007884	49.0	29118@1|root,2ZNNU@2|Bacteria,4P91J@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7738417_2	755732.Fluta_1803	1.401e-90	310.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,1HWR8@117743|Flavobacteriia,2PAWV@246874|Cryomorphaceae	976|Bacteroidetes	E	FAD dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
TLS3_k127_7738417_7	755732.Fluta_1805	7.267e-54	199.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1I22C@117743|Flavobacteriia,2PB0M@246874|Cryomorphaceae	976|Bacteroidetes	S	Phosphoribosyl transferase domain	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
TLS3_k127_7738417_3	755732.Fluta_1806	8.997e-74	250.0	COG0208@1|root,COG0208@2|Bacteria,4NG18@976|Bacteroidetes,1HXA5@117743|Flavobacteriia,2PAD3@246874|Cryomorphaceae	976|Bacteroidetes	F	Ribonucleotide reductase, small chain	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
TLS3_k127_7738639_3	755732.Fluta_1880	4.576e-143	462.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,1HZ9Z@117743|Flavobacteriia,2PC6E@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_7738639_10	1408433.JHXV01000010_gene497	2.464e-69	241.0	COG0491@1|root,COG0491@2|Bacteria,4NE2Y@976|Bacteroidetes,1I1QG@117743|Flavobacteriia,2PBNR@246874|Cryomorphaceae	976|Bacteroidetes	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_7738639_4	1123277.KB893243_gene345	1.758e-118	391.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,47JM5@768503|Cytophagia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
TLS3_k127_7738639_12	755732.Fluta_1885	2.969e-51	190.0	2A96P@1|root,30YBB@2|Bacteria,4PC3F@976|Bacteroidetes,1IMTS@117743|Flavobacteriia,2PC5P@246874|Cryomorphaceae	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
TLS3_k127_7738639_8	755732.Fluta_1712	9.819e-92	308.0	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,1HXDX@117743|Flavobacteriia,2PAPA@246874|Cryomorphaceae	976|Bacteroidetes	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
TLS3_k127_7738639_5	755732.Fluta_1711	2.272e-113	376.0	COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,1HWMJ@117743|Flavobacteriia,2PAAW@246874|Cryomorphaceae	976|Bacteroidetes	EJ	Asparaginase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
TLS3_k127_7738639_15	714943.Mucpa_1298	8.88e-10	60.0	COG1961@1|root,COG1961@2|Bacteria,4NHW0@976|Bacteroidetes,1IR5S@117747|Sphingobacteriia	976|Bacteroidetes	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
TLS3_k127_7738639_6	926562.Oweho_2038	5.53e-94	316.0	COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,1HXZK@117743|Flavobacteriia,2PBGI@246874|Cryomorphaceae	976|Bacteroidetes	U	MotA/TolQ/ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
TLS3_k127_7738639_14	1408433.JHXV01000006_gene2664	4.102e-22	105.0	COG0848@1|root,COG0848@2|Bacteria,4PIAV@976|Bacteroidetes,1IE7D@117743|Flavobacteriia,2PC0B@246874|Cryomorphaceae	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
TLS3_k127_7738639_13	1408433.JHXV01000006_gene2665	5.683e-25	110.0	COG0848@1|root,COG0848@2|Bacteria,4NKT1@976|Bacteroidetes,1I1CY@117743|Flavobacteriia,2PBWJ@246874|Cryomorphaceae	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
TLS3_k127_7738639_2	755732.Fluta_1766	8.177e-154	495.0	COG1979@1|root,COG1979@2|Bacteria,4NF1D@976|Bacteroidetes,1HWZX@117743|Flavobacteriia,2PA6C@246874|Cryomorphaceae	976|Bacteroidetes	C	Iron-containing alcohol dehydrogenase	yqhD	-	-	ko:K08325	ko00640,map00640	-	R02528	RC00739	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
TLS3_k127_7738639_9	755732.Fluta_1767	5.152e-84	290.0	COG1670@1|root,COG1670@2|Bacteria,4NQ6A@976|Bacteroidetes,1IBN1@117743|Flavobacteriia,2PBU7@246874|Cryomorphaceae	976|Bacteroidetes	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_7738639_7	755732.Fluta_1719	6.521e-92	306.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,1HX7R@117743|Flavobacteriia,2PASN@246874|Cryomorphaceae	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
TLS3_k127_7738639_0	755732.Fluta_1773	1.684e-250	779.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1HWYW@117743|Flavobacteriia,2PAE9@246874|Cryomorphaceae	976|Bacteroidetes	J	PFAM tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
TLS3_k127_7738639_1	755732.Fluta_1775	2.765e-182	579.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1HX2W@117743|Flavobacteriia,2PAMH@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Sigma-54 factor, Activator interacting domain (AID)	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
TLS3_k127_7741347_0	755732.Fluta_2092	7.207e-113	399.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1I0R3@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
TLS3_k127_7741347_1	1121007.AUML01000032_gene2745	5.022e-94	315.0	COG3741@1|root,COG3741@2|Bacteria,4NIN9@976|Bacteroidetes,1I0JT@117743|Flavobacteriia,2YH82@290174|Aquimarina	976|Bacteroidetes	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
TLS3_k127_7743028_1	755732.Fluta_0830	2.62e-79	270.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1HY0Q@117743|Flavobacteriia,2PAU7@246874|Cryomorphaceae	976|Bacteroidetes	J	SpoU rRNA Methylase family	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
TLS3_k127_7743028_0	755732.Fluta_0831	2.076e-189	602.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1HX43@117743|Flavobacteriia,2PAD1@246874|Cryomorphaceae	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
TLS3_k127_7743370_0	1313421.JHBV01000023_gene5166	4.03e-62	214.0	COG0500@1|root,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,1IVHP@117747|Sphingobacteriia	976|Bacteroidetes	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
TLS3_k127_7743370_4	1313421.JHBV01000007_gene4258	1.767e-22	112.0	COG1572@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3291@2|Bacteria,4NN8K@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF1735)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,Laminin_G_3
TLS3_k127_7743370_2	755732.Fluta_3115	9.066e-38	144.0	2DZIM@1|root,32VBN@2|Bacteria,4NTG0@976|Bacteroidetes,1I4SS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7743370_1	936455.KI421499_gene6838	2.267e-39	150.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,2TUPK@28211|Alphaproteobacteria,3JVM0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Mg-protoporphyrin IX monomethyl ester oxidative cyclase 66kD subunit	bchE	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
TLS3_k127_7757642_6	755732.Fluta_0516	3.264e-60	216.0	COG0477@1|root,COG1674@1|root,COG0477@2|Bacteria,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1HXBM@117743|Flavobacteriia,2PAJ7@246874|Cryomorphaceae	976|Bacteroidetes	D	Ftsk_gamma	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
TLS3_k127_7757642_2	755732.Fluta_0519	4.794e-120	395.0	COG0010@1|root,COG0010@2|Bacteria,4NE26@976|Bacteroidetes,1HZXW@117743|Flavobacteriia,2PAD4@246874|Cryomorphaceae	976|Bacteroidetes	E	Arginase family	rocF	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
TLS3_k127_7757642_0	755732.Fluta_0520	1.315e-274	857.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1HY2B@117743|Flavobacteriia,2PAKF@246874|Cryomorphaceae	976|Bacteroidetes	J	Arginyl tRNA synthetase N terminal domain	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
TLS3_k127_7757642_1	468059.AUHA01000006_gene2981	1.013e-128	425.0	COG1808@1|root,COG1808@2|Bacteria,4NDXI@976|Bacteroidetes,1IWQ1@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
TLS3_k127_7757642_5	1408473.JHXO01000004_gene269	6.195e-62	218.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,2FKYZ@200643|Bacteroidia	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
TLS3_k127_7757642_4	755732.Fluta_3903	6.788e-79	274.0	COG0382@1|root,COG0382@2|Bacteria,4NFRM@976|Bacteroidetes,1HYXA@117743|Flavobacteriia,2PB5E@246874|Cryomorphaceae	976|Bacteroidetes	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
TLS3_k127_7757642_3	755732.Fluta_3902	2.748e-84	284.0	COG0823@1|root,COG2885@1|root,COG3063@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,COG3063@2|Bacteria,4NE6G@976|Bacteroidetes,1INKT@117743|Flavobacteriia,2PA4S@246874|Cryomorphaceae	976|Bacteroidetes	MNU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
TLS3_k127_7760388_0	755732.Fluta_0704	0.0	1665.0	COG1629@1|root,COG4771@2|Bacteria,4NTQD@976|Bacteroidetes,1IKD4@117743|Flavobacteriia,2PA9C@246874|Cryomorphaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
TLS3_k127_7760388_1	755732.Fluta_0703	0.0	1542.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7760388_2	755732.Fluta_0702	7.655e-156	499.0	COG2067@1|root,COG2067@2|Bacteria,4NWE8@976|Bacteroidetes,1I8GR@117743|Flavobacteriia,2PAP2@246874|Cryomorphaceae	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_7760388_3	1408433.JHXV01000020_gene3547	1.532e-68	236.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,1I18I@117743|Flavobacteriia,2PAT2@246874|Cryomorphaceae	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
TLS3_k127_7760388_5	755732.Fluta_0699	2.145e-53	191.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,1I1YY@117743|Flavobacteriia,2PB01@246874|Cryomorphaceae	976|Bacteroidetes	FG	HIT domain	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
TLS3_k127_7760388_4	755732.Fluta_0697	8.787e-58	215.0	COG3291@1|root,COG3291@2|Bacteria,4NM0P@976|Bacteroidetes,1I0CF@117743|Flavobacteriia,2PAUX@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M14
TLS3_k127_7760388_6	1042376.AFPK01000001_gene1819	0.000686	44.0	COG3503@1|root,COG3503@2|Bacteria,4NG0X@976|Bacteroidetes,1HWX2@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
TLS3_k127_777791_1	1408433.JHXV01000016_gene1844	2.848e-166	529.0	COG1032@1|root,COG1032@2|Bacteria,4NH8Y@976|Bacteroidetes,1HZR8@117743|Flavobacteriia	976|Bacteroidetes	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
TLS3_k127_777791_2	1313421.JHBV01000029_gene1963	4.331e-55	200.0	COG2890@1|root,COG2890@2|Bacteria,4NN9I@976|Bacteroidetes,1IY41@117747|Sphingobacteriia	976|Bacteroidetes	J	Methyltransferase small domain	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
TLS3_k127_777791_3	1499967.BAYZ01000074_gene2111	5.667e-09	58.0	2EGPU@1|root,31UHW@2|Bacteria,2NRWE@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_777791_0	1469557.JSWF01000031_gene1986	1.185e-167	544.0	COG2192@1|root,COG2192@2|Bacteria,4NEV9@976|Bacteroidetes,1HZ9A@117743|Flavobacteriia	976|Bacteroidetes	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
TLS3_k127_7786656_3	1166016.W5S_0982	3.515e-24	107.0	2E9Z0@1|root,30JID@2|Bacteria,1QFK8@1224|Proteobacteria,1TCVK@1236|Gammaproteobacteria,1MTJP@122277|Pectobacterium	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7786656_4	1122129.AUEF01000027_gene2194	5.399e-16	82.0	2DZUB@1|root,32VJ7@2|Bacteria,1VB5N@1239|Firmicutes,4HN7B@91061|Bacilli,4GZEX@90964|Staphylococcaceae	91061|Bacilli	S	Novel toxin 21	-	-	-	-	-	-	-	-	-	-	-	-	Ntox21
TLS3_k127_7786656_2	929556.Solca_4428	9.483e-42	161.0	COG0457@1|root,COG0457@2|Bacteria,4NTP4@976|Bacteroidetes,1IUND@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7786656_0	1408433.JHXV01000005_gene2466	1.261e-230	722.0	COG0057@1|root,COG0057@2|Bacteria,4NG5C@976|Bacteroidetes,1HXX7@117743|Flavobacteriia,2PAGG@246874|Cryomorphaceae	976|Bacteroidetes	C	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gapA2	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
TLS3_k127_7786656_1	755732.Fluta_3405	4.969e-172	541.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1HWSN@117743|Flavobacteriia,2PBB2@246874|Cryomorphaceae	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS3_k127_7805656_2	755732.Fluta_0023	3.929e-79	275.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
TLS3_k127_7805656_0	755732.Fluta_0242	3.844e-159	508.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,1HY6T@117743|Flavobacteriia,2PAHB@246874|Cryomorphaceae	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
TLS3_k127_7805656_6	216432.CA2559_02120	9.393e-13	77.0	COG0457@1|root,COG3807@1|root,COG0457@2|Bacteria,COG3807@2|Bacteria,4NF5V@976|Bacteroidetes,1HYKU@117743|Flavobacteriia	976|Bacteroidetes	T	tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
TLS3_k127_7805656_3	755732.Fluta_1948	3.516e-67	250.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1HYP9@117743|Flavobacteriia,2PB93@246874|Cryomorphaceae	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
TLS3_k127_7805656_5	755732.Fluta_1947	1.849e-29	126.0	COG0457@1|root,COG0457@2|Bacteria,4NH2K@976|Bacteroidetes,1I1JW@117743|Flavobacteriia,2PB2Y@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	batC	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
TLS3_k127_7805656_4	755732.Fluta_1946	5.46e-63	231.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,1HYES@117743|Flavobacteriia,2PAY7@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM von Willebrand factor type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
TLS3_k127_7805656_1	755732.Fluta_1945	1.444e-101	341.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,1HWY3@117743|Flavobacteriia,2PARY@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM von Willebrand factor type A domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
TLS3_k127_7809381_1	755732.Fluta_1092	1.972e-232	722.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,TniB
TLS3_k127_7809381_2	1515615.HQ41_05100	1.99e-27	116.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,2FPKW@200643|Bacteroidia,22XTD@171551|Porphyromonadaceae	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_7809381_3	746697.Aeqsu_0195	9.392e-18	83.0	2C7CM@1|root,33DFK@2|Bacteria,4NXIQ@976|Bacteroidetes,1I6F3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7809381_4	649639.Bcell_0211	1.93e-12	77.0	2EJEH@1|root,33D5G@2|Bacteria,1W12X@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7809381_0	755732.Fluta_1094	0.0	1325.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,1IJBA@117743|Flavobacteriia,2PA8Z@246874|Cryomorphaceae	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
TLS3_k127_7820510_1	1408473.JHXO01000003_gene2584	1.092e-62	222.0	2E676@1|root,330VQ@2|Bacteria,4PA7N@976|Bacteroidetes,2FZJU@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7820510_0	755732.Fluta_2397	1.548e-297	919.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1HYV0@117743|Flavobacteriia,2PAMF@246874|Cryomorphaceae	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
TLS3_k127_7820510_2	1305737.JAFX01000001_gene152	5.419e-05	53.0	COG2972@1|root,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,47QDQ@768503|Cytophagia	976|Bacteroidetes	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,TPR_12,TPR_7,TPR_8
TLS3_k127_7841437_0	1341181.FLJC2902T_12750	0.0	1903.0	2DM7Q@1|root,322X9@2|Bacteria,4NKDH@976|Bacteroidetes,1HZT2@117743|Flavobacteriia,2NUI7@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7841437_1	1341181.FLJC2902T_12740	0.0	1593.0	COG2304@1|root,COG2304@2|Bacteria,4NH1J@976|Bacteroidetes,1I7SD@117743|Flavobacteriia,2NVMF@237|Flavobacterium	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7841437_2	1121931.AUHG01000017_gene1562	6.38e-58	218.0	COG4974@1|root,COG4974@2|Bacteria,4NIUH@976|Bacteroidetes,1IJET@117743|Flavobacteriia	976|Bacteroidetes	L	Phage integrase SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase
TLS3_k127_7848517_1	755732.Fluta_3582	4.954e-98	324.0	COG1396@1|root,COG1974@1|root,COG1396@2|Bacteria,COG1974@2|Bacteria,4PKQ7@976|Bacteroidetes,1IJGW@117743|Flavobacteriia,2PAZ2@246874|Cryomorphaceae	976|Bacteroidetes	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
TLS3_k127_7848517_0	755732.Fluta_3581	3.967e-182	589.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,1HX0Y@117743|Flavobacteriia,2PA7X@246874|Cryomorphaceae	976|Bacteroidetes	L	TIGRFAM ATP-dependent DNA helicase, RecQ family	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
TLS3_k127_7848517_2	755732.Fluta_3579	2.157e-73	251.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1HY87@117743|Flavobacteriia,2PAET@246874|Cryomorphaceae	976|Bacteroidetes	EH	TIGRFAM branched-chain amino acid aminotransferase, group II	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_7853268_7	313595.P700755_000740	0.0003987	44.0	COG2849@1|root,COG2849@2|Bacteria,4NTSP@976|Bacteroidetes	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
TLS3_k127_7853268_0	755732.Fluta_0245	6.497e-275	859.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1HWVC@117743|Flavobacteriia,2PAHZ@246874|Cryomorphaceae	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
TLS3_k127_7853268_3	755732.Fluta_0118	1.151e-108	356.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,1HX38@117743|Flavobacteriia,2PAGE@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
TLS3_k127_7853268_4	755732.Fluta_0111	1.681e-98	325.0	COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,1HXW4@117743|Flavobacteriia,2PAZY@246874|Cryomorphaceae	976|Bacteroidetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
TLS3_k127_7853268_1	755732.Fluta_0110	2.006e-128	415.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,1HY0R@117743|Flavobacteriia,2PAPG@246874|Cryomorphaceae	976|Bacteroidetes	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
TLS3_k127_7853268_2	755732.Fluta_1992	4.026e-119	394.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia,2PAAN@246874|Cryomorphaceae	976|Bacteroidetes	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase CLD	ppiB	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,Pro_isomerase
TLS3_k127_7853268_6	755732.Fluta_1914	4.436e-76	264.0	COG3637@1|root,COG3637@2|Bacteria,4NUEN@976|Bacteroidetes,1IC3X@117743|Flavobacteriia,2PB1K@246874|Cryomorphaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
TLS3_k127_7853268_5	755732.Fluta_0107	1.487e-78	269.0	COG5316@1|root,COG5316@2|Bacteria,4NGER@976|Bacteroidetes,1IJGS@117743|Flavobacteriia	976|Bacteroidetes	P	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140,Plug
TLS3_k127_7879541_0	755732.Fluta_4080	1.498e-127	421.0	COG1752@1|root,COG1752@2|Bacteria,4NF97@976|Bacteroidetes,1IMPM@117743|Flavobacteriia,2PAJF@246874|Cryomorphaceae	976|Bacteroidetes	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
TLS3_k127_7887948_1	755732.Fluta_2925	1.036e-97	341.0	COG0683@1|root,COG1388@1|root,COG0683@2|Bacteria,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,1HY84@117743|Flavobacteriia,2PB0J@246874|Cryomorphaceae	976|Bacteroidetes	EM	Lysin motif	lysM	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
TLS3_k127_7887948_0	755732.Fluta_2924	4.261e-296	913.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,1HX9A@117743|Flavobacteriia,2PAFZ@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
TLS3_k127_7899315_1	1408433.JHXV01000021_gene1633	7.247e-68	246.0	COG1073@1|root,COG1073@2|Bacteria,4NH47@976|Bacteroidetes,1HYN1@117743|Flavobacteriia,2PC1H@246874|Cryomorphaceae	976|Bacteroidetes	S	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,DLH,Hydrolase_4,Peptidase_S9
TLS3_k127_7899315_3	313596.RB2501_11392	2.586e-31	138.0	2ASGC@1|root,31HWH@2|Bacteria,4NR0Q@976|Bacteroidetes,1I25V@117743|Flavobacteriia	976|Bacteroidetes	S	Excinuclease ABC subunit B	-	-	-	-	-	-	-	-	-	-	-	-	TerB
TLS3_k127_7899315_2	755732.Fluta_3620	3.12e-36	142.0	COG3011@1|root,COG3011@2|Bacteria,4PIV8@976|Bacteroidetes,1ICSK@117743|Flavobacteriia,2PC05@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
TLS3_k127_7899315_0	755732.Fluta_2801	6.122e-162	512.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,1HWQX@117743|Flavobacteriia,2PA8X@246874|Cryomorphaceae	976|Bacteroidetes	C	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
TLS3_k127_7930152_7	1239962.C943_02799	9.106e-47	183.0	COG2114@1|root,COG3292@1|root,COG2114@2|Bacteria,COG3292@2|Bacteria,4NEVN@976|Bacteroidetes,47MR3@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,Reg_prop,Response_reg,TPR_12,Y_Y_Y
TLS3_k127_7930152_1	641526.ADIWIN_3234	1.452e-183	585.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,1HY2V@117743|Flavobacteriia	976|Bacteroidetes	Q	Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
TLS3_k127_7930152_9	866536.Belba_0371	5.71e-19	97.0	COG1073@1|root,COG1073@2|Bacteria,4NQNM@976|Bacteroidetes,47RYB@768503|Cytophagia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
TLS3_k127_7930152_4	1296415.JACC01000059_gene1021	7.247e-111	369.0	COG3509@1|root,COG3509@2|Bacteria,4NHFS@976|Bacteroidetes,1I3VW@117743|Flavobacteriia	976|Bacteroidetes	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase,Esterase_phd
TLS3_k127_7930152_8	1317122.ATO12_00390	1.138e-39	154.0	COG3758@1|root,COG3758@2|Bacteria,4NTC4@976|Bacteroidetes,1I6UV@117743|Flavobacteriia,2YIV5@290174|Aquimarina	976|Bacteroidetes	S	HutD	-	-	-	-	-	-	-	-	-	-	-	-	HutD
TLS3_k127_7930152_0	755732.Fluta_1283	2.709e-281	870.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1HX3I@117743|Flavobacteriia,2PA90@246874|Cryomorphaceae	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_7930152_2	1408433.JHXV01000006_gene2694	1.58e-131	433.0	COG0025@1|root,COG0025@2|Bacteria,4NK07@976|Bacteroidetes,1HWM6@117743|Flavobacteriia	976|Bacteroidetes	P	Pfam Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
TLS3_k127_7930152_10	1358423.N180_16485	2.581e-12	72.0	COG2146@1|root,COG2146@2|Bacteria,4NV9E@976|Bacteroidetes,1ITVU@117747|Sphingobacteriia	976|Bacteroidetes	P	Rieske (2Fe-2S) domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske,Rieske_2
TLS3_k127_7930152_3	755732.Fluta_1481	2.588e-128	418.0	COG0604@1|root,COG0604@2|Bacteria,4NEYW@976|Bacteroidetes,1HYX1@117743|Flavobacteriia,2PBCQ@246874|Cryomorphaceae	976|Bacteroidetes	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,MaoC_dehydratas
TLS3_k127_7930152_5	755732.Fluta_1483	4.655e-93	312.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,1HX5Y@117743|Flavobacteriia,2PAPP@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
TLS3_k127_7930152_6	755732.Fluta_1484	8.749e-64	224.0	COG1714@1|root,COG1714@2|Bacteria,4NH7U@976|Bacteroidetes,1HY9K@117743|Flavobacteriia,2PB0H@246874|Cryomorphaceae	976|Bacteroidetes	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
TLS3_k127_7933810_6	760192.Halhy_3663	3.807e-24	107.0	2CD9X@1|root,2ZIYV@2|Bacteria,4P962@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7933810_1	1408433.JHXV01000018_gene3807	3.606e-108	368.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7933810_3	755732.Fluta_0288	9.767e-59	205.0	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,1I1Z2@117743|Flavobacteriia,2PAVK@246874|Cryomorphaceae	976|Bacteroidetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
TLS3_k127_7933810_5	755732.Fluta_0289	6.934e-27	110.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,1I52P@117743|Flavobacteriia,2PB67@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
TLS3_k127_7933810_2	755732.Fluta_0290	7.254e-82	275.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,1I178@117743|Flavobacteriia,2PAWT@246874|Cryomorphaceae	976|Bacteroidetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
TLS3_k127_7933810_0	755732.Fluta_0291	0.0	1109.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,1HX1R@117743|Flavobacteriia,2PA7I@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
TLS3_k127_7933810_4	755732.Fluta_2219	3.047e-33	135.0	COG2197@1|root,COG2197@2|Bacteria,4NN0B@976|Bacteroidetes,1I0A6@117743|Flavobacteriia	976|Bacteroidetes	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_7936545_11	1233950.IW22_18365	1.11e-05	56.0	COG4733@1|root,COG4733@2|Bacteria,4PNEQ@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
TLS3_k127_7936545_2	1185876.BN8_02865	4.348e-123	426.0	COG0745@1|root,COG1956@1|root,COG5002@1|root,COG0745@2|Bacteria,COG1956@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,47YRP@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HTH_18,HisKA,Response_reg,TPR_10,TPR_12,TPR_7,TPR_8
TLS3_k127_7936545_4	1408473.JHXO01000006_gene1321	2.444e-101	335.0	COG0564@1|root,COG0564@2|Bacteria,4NHCT@976|Bacteroidetes,2FNNK@200643|Bacteroidia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS3_k127_7936545_7	1313421.JHBV01000014_gene3816	4.856e-36	154.0	COG3291@1|root,COG5306@1|root,COG3291@2|Bacteria,COG5306@2|Bacteria,4NRAB@976|Bacteroidetes	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Calycin_like,PCMD
TLS3_k127_7936545_3	755732.Fluta_0491	3.569e-121	394.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,1HXCX@117743|Flavobacteriia,2PAJ4@246874|Cryomorphaceae	976|Bacteroidetes	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
TLS3_k127_7936545_1	755732.Fluta_2588	3.346e-164	535.0	COG2374@1|root,COG2374@2|Bacteria,4NJUY@976|Bacteroidetes,1HXYB@117743|Flavobacteriia,2PBQS@246874|Cryomorphaceae	976|Bacteroidetes	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7936545_8	1229487.AMYW01000007_gene3197	1.57e-17	85.0	2EMJ4@1|root,33F7P@2|Bacteria,4NYXT@976|Bacteroidetes,1I5IS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7936545_9	153721.MYP_3932	4.378e-09	57.0	COG2274@1|root,COG2274@2|Bacteria,4NE19@976|Bacteroidetes,47JYM@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
TLS3_k127_7936545_0	1461577.CCMH01000046_gene870	0.0	1083.0	COG0286@1|root,COG0286@2|Bacteria,4NFQR@976|Bacteroidetes,1I0BR@117743|Flavobacteriia	976|Bacteroidetes	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
TLS3_k127_7936545_6	1461577.CCMH01000046_gene869	1.792e-57	226.0	COG0732@1|root,COG0732@2|Bacteria,4NIPK@976|Bacteroidetes,1I56H@117743|Flavobacteriia	976|Bacteroidetes	V	Type I restriction modification DNA specificity domain	-	-	-	-	-	-	-	-	-	-	-	-	Methylase_S
TLS3_k127_7936545_12	1235802.C823_06184	0.0002416	44.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,25UWZ@186806|Eubacteriaceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
TLS3_k127_7936545_5	1296415.JACC01000030_gene2776	2.527e-89	302.0	COG3209@1|root,COG3209@2|Bacteria,4NF0G@976|Bacteroidetes,1I0VK@117743|Flavobacteriia	976|Bacteroidetes	M	RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midN
TLS3_k127_7938204_2	641524.ADICYQ_5999	2.024e-15	88.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,4PM1S@976|Bacteroidetes,47R6W@768503|Cytophagia	976|Bacteroidetes	C	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7938204_1	755732.Fluta_1811	2.691e-41	167.0	COG1357@1|root,COG4932@1|root,COG1357@2|Bacteria,COG4932@2|Bacteria,4PP0I@976|Bacteroidetes,1IKDM@117743|Flavobacteriia,2PC6K@246874|Cryomorphaceae	2|Bacteria	U	SPTR Conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Collagen_bind,DUF11,DUF1566,Pentapeptide,SdrD_B
TLS3_k127_7938204_0	755732.Fluta_2749	1.245e-268	830.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1HWVS@117743|Flavobacteriia,2PAHG@246874|Cryomorphaceae	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_7941787_5	755732.Fluta_1076	1.025e-12	70.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1ICNV@117743|Flavobacteriia,2PBDQ@246874|Cryomorphaceae	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_7941787_2	755732.Fluta_1075	7.841e-38	151.0	COG2267@1|root,COG2267@2|Bacteria,4NHA9@976|Bacteroidetes,1HY0U@117743|Flavobacteriia,2PB1M@246874|Cryomorphaceae	976|Bacteroidetes	I	Serine aminopeptidase, S33	yfbB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_7941787_0	755732.Fluta_1074	1.291e-217	681.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,1HZDM@117743|Flavobacteriia,2PACK@246874|Cryomorphaceae	976|Bacteroidetes	E	Aminopeptidase P, N-terminal domain	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
TLS3_k127_7941787_3	755732.Fluta_1072	1.595e-36	148.0	2AEZ8@1|root,314X9@2|Bacteria,4PJ5J@976|Bacteroidetes,1ICT1@117743|Flavobacteriia,2PC21@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7941787_1	755732.Fluta_1071	4.762e-88	296.0	COG0504@1|root,COG0504@2|Bacteria,4PHI1@976|Bacteroidetes,1IMS3@117743|Flavobacteriia,2PBUX@246874|Cryomorphaceae	976|Bacteroidetes	F	CTP synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7941787_4	926556.Echvi_1813	3.68e-24	102.0	COG0328@1|root,COG0328@2|Bacteria,4NNQX@976|Bacteroidetes,47PXE@768503|Cytophagia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
TLS3_k127_7945013_7	755732.Fluta_1125	8.282e-33	129.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,1I14P@117743|Flavobacteriia,2PBAQ@246874|Cryomorphaceae	976|Bacteroidetes	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
TLS3_k127_7945013_3	1408433.JHXV01000008_gene209	2.309e-79	291.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
TLS3_k127_7945013_0	755732.Fluta_0072	4.382e-268	852.0	COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,1IKD0@117743|Flavobacteriia,2PAFR@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_7945013_5	392500.Swoo_2843	1.167e-39	158.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,2Q9D1@267890|Shewanellaceae	1236|Gammaproteobacteria	GM	PFAM NAD-dependent epimerase dehydratase	yeeZ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
TLS3_k127_7945013_1	755732.Fluta_0066	1.351e-116	389.0	COG1612@1|root,COG1612@2|Bacteria,4NEBR@976|Bacteroidetes,1HWUP@117743|Flavobacteriia,2PAT7@246874|Cryomorphaceae	976|Bacteroidetes	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
TLS3_k127_7945013_4	1286632.P278_20950	5.663e-52	193.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,1HWSW@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_7945013_2	746697.Aeqsu_0092	2.763e-99	334.0	COG0451@1|root,COG0451@2|Bacteria,4NI4C@976|Bacteroidetes,1HYXU@117743|Flavobacteriia	976|Bacteroidetes	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	3Beta_HSD,Epimerase
TLS3_k127_7945013_6	755732.Fluta_4002	1.21e-36	144.0	COG4704@1|root,COG4704@2|Bacteria,4P9RE@976|Bacteroidetes,1ICNA@117743|Flavobacteriia,2PB7B@246874|Cryomorphaceae	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
TLS3_k127_7945013_8	1128912.GMES_2660	4.441e-07	62.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,4648Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
TLS3_k127_7949253_4	1492738.FEM21_25620	2.145e-44	163.0	COG1695@1|root,COG1695@2|Bacteria,4NSI4@976|Bacteroidetes,1I2SA@117743|Flavobacteriia,2NW99@237|Flavobacterium	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
TLS3_k127_7949253_2	1408433.JHXV01000026_gene3035	1.972e-48	192.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,1HX01@117743|Flavobacteriia,2PAXN@246874|Cryomorphaceae	976|Bacteroidetes	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
TLS3_k127_7949253_3	945713.IALB_1794	1.53e-44	169.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
TLS3_k127_7949253_5	1122179.KB890415_gene2006	9.856e-29	119.0	COG4551@1|root,COG4551@2|Bacteria,4NV24@976|Bacteroidetes	976|Bacteroidetes	S	Low molecular weight phosphotyrosine protein phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7949253_1	1408433.JHXV01000023_gene3306	8.481e-71	253.0	28KF4@1|root,2ZA1C@2|Bacteria,4NNRR@976|Bacteroidetes,1IG92@117743|Flavobacteriia,2PBQ4@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BetR
TLS3_k127_7949253_0	755732.Fluta_4034	1.792e-137	443.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,4PKKU@976|Bacteroidetes,1IJC1@117743|Flavobacteriia,2PARD@246874|Cryomorphaceae	976|Bacteroidetes	L	GIY-YIG type nucleases (URI domain)	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
TLS3_k127_7960125_4	755732.Fluta_1213	2.777e-85	292.0	COG1112@1|root,COG1112@2|Bacteria,4NF2S@976|Bacteroidetes,1I1IU@117743|Flavobacteriia,2PBBT@246874|Cryomorphaceae	976|Bacteroidetes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011,WGR
TLS3_k127_7960125_3	755732.Fluta_1316	7.276e-94	316.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,1HY13@117743|Flavobacteriia,2PBFZ@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_7960125_9	755732.Fluta_1315	1.613e-48	183.0	COG1277@1|root,COG1277@2|Bacteria,4NEES@976|Bacteroidetes,1HYGY@117743|Flavobacteriia,2PC17@246874|Cryomorphaceae	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4
TLS3_k127_7960125_0	1121285.AUFK01000013_gene2084	2.018e-170	554.0	COG2957@1|root,COG2957@2|Bacteria,4NGF8@976|Bacteroidetes,1HYT2@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the agmatine deiminase family	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
TLS3_k127_7960125_2	1313421.JHBV01000007_gene4290	1.532e-129	424.0	2C57D@1|root,2Z7RS@2|Bacteria,4NEKN@976|Bacteroidetes,1IPC9@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
TLS3_k127_7960125_10	1293054.HSACCH_00794	4.322e-07	59.0	COG0666@1|root,COG0666@2|Bacteria,1VD85@1239|Firmicutes,24RSD@186801|Clostridia	186801|Clostridia	S	response to abiotic stimulus	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7960125_7	1237149.C900_04180	1.082e-55	218.0	COG2339@1|root,COG2339@2|Bacteria,4NGUS@976|Bacteroidetes,47Q0J@768503|Cytophagia	976|Bacteroidetes	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
TLS3_k127_7960125_6	1185876.BN8_05369	7.292e-58	218.0	COG1216@1|root,COG1216@2|Bacteria,4PKUG@976|Bacteroidetes,47YDT@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GT87
TLS3_k127_7960125_1	592029.DDD_2468	1.665e-141	464.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,1HWMV@117743|Flavobacteriia,3HJKQ@363408|Nonlabens	976|Bacteroidetes	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_7960125_5	592029.DDD_2467	5.507e-82	299.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
TLS3_k127_7960125_8	592029.DDD_2466	1.51e-53	199.0	COG2755@1|root,COG2755@2|Bacteria,4P2RQ@976|Bacteroidetes	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7972903_12	742726.HMPREF9448_00937	4.318e-84	282.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,2FMS7@200643|Bacteroidia,22WJC@171551|Porphyromonadaceae	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
TLS3_k127_7972903_17	1122176.KB903532_gene2558	2.52e-24	109.0	2AN5I@1|root,31D3D@2|Bacteria,4NQTI@976|Bacteroidetes,1ITEI@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
TLS3_k127_7972903_15	237368.SCABRO_03508	3.446e-42	170.0	COG2995@1|root,COG2995@2|Bacteria	2|Bacteria	S	response to heat	pqiA2	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
TLS3_k127_7972903_3	755732.Fluta_2349	3.975e-302	935.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,1HXCS@117743|Flavobacteriia,2PA9H@246874|Cryomorphaceae	976|Bacteroidetes	C	Acyl-CoA dehydrogenase, C-terminal domain	fadE	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_7972903_10	1296416.JACB01000001_gene3535	1.389e-97	329.0	COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,1HWNT@117743|Flavobacteriia,2YGY7@290174|Aquimarina	976|Bacteroidetes	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GTA_TIM
TLS3_k127_7972903_9	742767.HMPREF9456_00204	5.748e-116	387.0	COG0513@1|root,COG0513@2|Bacteria,4NE4Z@976|Bacteroidetes,2FNFU@200643|Bacteroidia,22WHN@171551|Porphyromonadaceae	976|Bacteroidetes	L	DbpA RNA binding domain	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
TLS3_k127_7972903_5	755732.Fluta_2447	2.325e-208	652.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HWRC@117743|Flavobacteriia,2PAEC@246874|Cryomorphaceae	976|Bacteroidetes	I	Thiolase, C-terminal domain	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
TLS3_k127_7972903_1	1408433.JHXV01000009_gene1331	0.0	1212.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1HY3C@117743|Flavobacteriia,2PA69@246874|Cryomorphaceae	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
TLS3_k127_7972903_14	755732.Fluta_2449	7.892e-47	173.0	COG1846@1|root,COG1846@2|Bacteria,4NNK7@976|Bacteroidetes,1I24N@117743|Flavobacteriia,2PB2P@246874|Cryomorphaceae	976|Bacteroidetes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
TLS3_k127_7972903_16	755732.Fluta_2450	1.029e-33	135.0	COG2050@1|root,COG2050@2|Bacteria,4NM7W@976|Bacteroidetes,1I2P9@117743|Flavobacteriia,2PB1D@246874|Cryomorphaceae	976|Bacteroidetes	Q	Thioesterase superfamily	paaI	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
TLS3_k127_7972903_13	755732.Fluta_2451	3.148e-47	175.0	2AAMS@1|root,30ZZG@2|Bacteria,4PEB8@976|Bacteroidetes,1IMSF@117743|Flavobacteriia,2PBYB@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7972903_11	755732.Fluta_2452	8.022e-86	291.0	COG5587@1|root,COG5587@2|Bacteria,4NRNM@976|Bacteroidetes,1I8TV@117743|Flavobacteriia,2PATJ@246874|Cryomorphaceae	976|Bacteroidetes	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
TLS3_k127_7972903_4	755732.Fluta_2453	7.073e-286	893.0	COG1506@1|root,COG1506@2|Bacteria,4NF7I@976|Bacteroidetes,1HXW2@117743|Flavobacteriia,2PAA6@246874|Cryomorphaceae	976|Bacteroidetes	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	ptpA	-	3.4.14.12,3.4.14.5	ko:K01278,ko:K18574	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
TLS3_k127_7972903_2	755732.Fluta_2455	0.0	1211.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1HXMC@117743|Flavobacteriia,2PAFP@246874|Cryomorphaceae	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
TLS3_k127_7972903_8	755732.Fluta_2456	1.598e-129	420.0	COG1044@1|root,COG1044@2|Bacteria,4NFXA@976|Bacteroidetes,1HXWG@117743|Flavobacteriia,2PA7U@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM UDP-3-O- 3-hydroxymyristoyl glucosamine N-acyltransferase, LpxD	lpxD1	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
TLS3_k127_7972903_6	755732.Fluta_2457	2.656e-169	541.0	COG2208@1|root,COG2208@2|Bacteria,4NI98@976|Bacteroidetes,1IMQG@117743|Flavobacteriia,2PBAV@246874|Cryomorphaceae	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
TLS3_k127_7972903_7	1185876.BN8_02608	1.104e-149	479.0	COG0451@1|root,COG0451@2|Bacteria,4NHI3@976|Bacteroidetes,47NYF@768503|Cytophagia	976|Bacteroidetes	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS3_k127_7972903_0	755732.Fluta_2459	0.0	1447.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IMQK@117743|Flavobacteriia,2PBES@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
TLS3_k127_7978373_3	755732.Fluta_3219	8.677e-83	277.0	COG1257@1|root,COG1257@2|Bacteria,4NGNG@976|Bacteroidetes,1HY0M@117743|Flavobacteriia,2PBG7@246874|Cryomorphaceae	976|Bacteroidetes	C	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
TLS3_k127_7978373_1	755732.Fluta_3220	4.927e-187	588.0	COG1304@1|root,COG1304@2|Bacteria,4NJPE@976|Bacteroidetes	976|Bacteroidetes	C	COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid	-	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
TLS3_k127_7978373_0	755732.Fluta_3221	3.589e-211	662.0	COG0654@1|root,COG0654@2|Bacteria,4P13Y@976|Bacteroidetes,1I7EV@117743|Flavobacteriia	976|Bacteroidetes	C	Squalene epoxidase	-	-	1.14.14.17	ko:K00511	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R02874	RC00201	ko00000,ko00001,ko01000	-	-	-	SE
TLS3_k127_7978373_2	755732.Fluta_3222	1.288e-177	562.0	COG1562@1|root,COG1562@2|Bacteria,4P1FV@976|Bacteroidetes,1I86Z@117743|Flavobacteriia	976|Bacteroidetes	I	Squalene/phytoene synthase	-	-	2.5.1.21	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R00702,R02872,R06223	RC00362,RC00796,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	SQS_PSY
TLS3_k127_7978373_4	755732.Fluta_2821	7.284e-45	167.0	2DBBI@1|root,2Z888@2|Bacteria,4NQB6@976|Bacteroidetes,1I62S@117743|Flavobacteriia	976|Bacteroidetes	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	YHYH
TLS3_k127_7992505_3	926562.Oweho_0387	2.999e-10	63.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1HY2Q@117743|Flavobacteriia,2PBZ4@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6
TLS3_k127_7992505_4	1484460.JSWG01000011_gene1735	2.288e-05	53.0	28IM1@1|root,2Z8MK@2|Bacteria,4NIZ0@976|Bacteroidetes,1HYU0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7992505_0	755732.Fluta_3508	1.561e-298	921.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,1HWP2@117743|Flavobacteriia,2PAB9@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
TLS3_k127_7992505_1	755732.Fluta_3509	6.13e-204	653.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,1HWSE@117743|Flavobacteriia,2PAKQ@246874|Cryomorphaceae	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
TLS3_k127_7992505_2	925409.KI911562_gene863	1.369e-58	209.0	COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,1IPKV@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	fabH1	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
TLS3_k127_8015789_1	319236.JCM19294_758	0.0001459	51.0	COG1345@1|root,COG1404@1|root,COG3897@1|root,COG1345@2|Bacteria,COG1404@2|Bacteria,COG3897@2|Bacteria,4PMFM@976|Bacteroidetes,1IJSB@117743|Flavobacteriia,3HJU7@363408|Nonlabens	976|Bacteroidetes	N	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_8015789_0	28072.Nos7524_0564	4.227e-06	56.0	COG2374@1|root,COG2931@1|root,COG3391@1|root,COG2374@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,1G0YK@1117|Cyanobacteria,1HM71@1161|Nostocales	1117|Cyanobacteria	Q	phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	5_nucleotid_C,DUF4114,Exo_endo_phos,Phytase-like,VPEP
TLS3_k127_8034413_0	755732.Fluta_2650	2.123e-158	519.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4P15I@976|Bacteroidetes,1IE72@117743|Flavobacteriia,2PBDD@246874|Cryomorphaceae	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
TLS3_k127_8034413_1	755732.Fluta_2649	2.639e-94	316.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,1HXW3@117743|Flavobacteriia,2PAP6@246874|Cryomorphaceae	976|Bacteroidetes	L	EXOIII	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
TLS3_k127_8034413_2	755732.Fluta_2648	3.823e-86	289.0	COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,1HX6X@117743|Flavobacteriia,2PASW@246874|Cryomorphaceae	976|Bacteroidetes	Q	Fumarylacetoacetate (FAA) hydrolase family	fahA	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
TLS3_k127_8057207_1	1168065.DOK_10502	6.252e-28	113.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1J4ZR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
TLS3_k127_8057207_0	1408433.JHXV01000036_gene264	0.0	1131.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,2PBB4@246874|Cryomorphaceae	976|Bacteroidetes	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
TLS3_k127_8066180_4	755732.Fluta_1629	1.143e-08	59.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	srrB	-	-	-	-	-	-	-	-	-	-	-	CBS,HAMP,SpoIIE,dCache_1
TLS3_k127_8066180_0	1408433.JHXV01000005_gene2329	1.064e-300	929.0	COG2759@1|root,COG2759@2|Bacteria,4NG3E@976|Bacteroidetes,1HXR5@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
TLS3_k127_8066180_1	1237149.C900_02223	6.653e-135	437.0	COG1216@1|root,COG1216@2|Bacteria,4NGD0@976|Bacteroidetes	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_8066180_2	1380600.AUYN01000001_gene2402	1.852e-88	297.0	COG0730@1|root,COG0730@2|Bacteria,4NIJ9@976|Bacteroidetes,1I0SR@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_8086751_3	1408433.JHXV01000001_gene709	4.346e-27	115.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,1IGBV@117743|Flavobacteriia,2PB74@246874|Cryomorphaceae	976|Bacteroidetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
TLS3_k127_8086751_1	1229487.AMYW01000003_gene1865	2.089e-35	141.0	COG0545@1|root,COG0545@2|Bacteria,4NQJS@976|Bacteroidetes,1I376@117743|Flavobacteriia,2NWCH@237|Flavobacterium	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
TLS3_k127_8086751_0	314271.RB2654_04259	5.03e-57	210.0	2F607@1|root,33YIP@2|Bacteria,1NYAX@1224|Proteobacteria	1224|Proteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8086751_2	688270.Celal_1772	4.211e-33	141.0	2AMNN@1|root,31CIT@2|Bacteria,4NS0X@976|Bacteroidetes,1I5J0@117743|Flavobacteriia,1F92Y@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8113755_0	1408433.JHXV01000016_gene1820	1.465e-78	297.0	COG3210@1|root,COG3210@2|Bacteria,4P1PQ@976|Bacteroidetes,1ICP0@117743|Flavobacteriia,2PBF7@246874|Cryomorphaceae	976|Bacteroidetes	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8121907_0	926562.Oweho_2464	5.417e-121	406.0	COG4409@1|root,COG4409@2|Bacteria,4PBA1@976|Bacteroidetes,1ICPD@117743|Flavobacteriia,2PBHN@246874|Cryomorphaceae	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8121907_2	1279019.ARQK01000049_gene20	2.488e-08	61.0	2EPQJ@1|root,33HB4@2|Bacteria,1NIAD@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3634
TLS3_k127_8121907_1	929704.Myrod_3297	1.064e-51	188.0	COG1670@1|root,COG1670@2|Bacteria,4NQEC@976|Bacteroidetes,1I3F6@117743|Flavobacteriia,47J0Y@76831|Myroides	976|Bacteroidetes	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
TLS3_k127_8127602_0	926562.Oweho_1986	1.071e-310	969.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1HXF4@117743|Flavobacteriia,2PA8K@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
TLS3_k127_8127602_1	926562.Oweho_1985	2.146e-24	109.0	2BIIZ@1|root,32CRR@2|Bacteria,4PJT2@976|Bacteroidetes,1IHI5@117743|Flavobacteriia,2PB50@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
TLS3_k127_8128458_0	1121904.ARBP01000032_gene2024	1.584e-69	263.0	COG1629@1|root,COG4771@2|Bacteria,4NKZP@976|Bacteroidetes,47NF4@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
TLS3_k127_815194_2	991.IW20_24430	8.731e-186	591.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1HX34@117743|Flavobacteriia,2NSH4@237|Flavobacterium	976|Bacteroidetes	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
TLS3_k127_815194_0	946077.W5A_07717	1.504e-273	857.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1HX1Z@117743|Flavobacteriia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
TLS3_k127_815194_1	755732.Fluta_0664	3.4e-253	793.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1HXQU@117743|Flavobacteriia,2PBAM@246874|Cryomorphaceae	976|Bacteroidetes	I	AMP-binding enzyme	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
TLS3_k127_815194_5	1408433.JHXV01000001_gene1082	1.181e-51	187.0	COG1595@1|root,COG1595@2|Bacteria,4NMJ7@976|Bacteroidetes,1I1YB@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_815194_3	755732.Fluta_2549	4.185e-137	439.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1HZRC@117743|Flavobacteriia,2PANF@246874|Cryomorphaceae	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_8157355_2	1347342.BN863_25470	2.662e-106	348.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,1HY4C@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
TLS3_k127_8157355_0	1107311.Q767_15255	9.973e-243	760.0	2C2EF@1|root,33QV2@2|Bacteria,4P1M6@976|Bacteroidetes,1I8BY@117743|Flavobacteriia,2NTAC@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8157355_1	1121896.JMLU01000016_gene1712	1.636e-107	353.0	2DNF6@1|root,32X6Q@2|Bacteria,4NZSW@976|Bacteroidetes,1I8IJ@117743|Flavobacteriia,2NS8R@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8292994_2	1408433.JHXV01000009_gene1354	2.882e-22	101.0	2E6TM@1|root,331DG@2|Bacteria,4NYW8@976|Bacteroidetes,1I8QW@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
TLS3_k127_8292994_1	1313421.JHBV01000019_gene5328	4.32e-138	453.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
TLS3_k127_8292994_0	1408433.JHXV01000017_gene1561	8.56e-164	533.0	COG0249@1|root,COG0249@2|Bacteria,4NE6X@976|Bacteroidetes,1HX6A@117743|Flavobacteriia,2PA8T@246874|Cryomorphaceae	976|Bacteroidetes	L	ATPase domain of DNA mismatch repair MUTS family	mutS_2	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
TLS3_k127_8316848_5	743722.Sph21_0303	1.235e-76	263.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1IRMS@117747|Sphingobacteriia	976|Bacteroidetes	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
TLS3_k127_8316848_8	755732.Fluta_3174	7.694e-37	140.0	COG2127@1|root,COG2127@2|Bacteria,4NS8R@976|Bacteroidetes,1I3WR@117743|Flavobacteriia,2PB69@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM ATP-dependent Clp protease adaptor protein ClpS	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
TLS3_k127_8316848_1	755732.Fluta_3173	8.959e-265	895.0	COG0419@1|root,COG1196@1|root,COG3391@1|root,COG0419@2|Bacteria,COG1196@2|Bacteria,COG3391@2|Bacteria,4PP0U@976|Bacteroidetes,1ICPT@117743|Flavobacteriia,2PBJT@246874|Cryomorphaceae	976|Bacteroidetes	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8316848_7	755732.Fluta_3172	2.058e-65	229.0	COG0344@1|root,COG0344@2|Bacteria,4NMU3@976|Bacteroidetes,1ICQQ@117743|Flavobacteriia,2PBSP@246874|Cryomorphaceae	976|Bacteroidetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
TLS3_k127_8316848_0	755732.Fluta_3171	0.0	1660.0	28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,1I791@117743|Flavobacteriia,2PA5S@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8316848_3	755732.Fluta_3170	6.993e-93	313.0	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,1HXXE@117743|Flavobacteriia,2PAT5@246874|Cryomorphaceae	976|Bacteroidetes	J	PFAM Ribosomal protein L11 methyltransferase (PrmA)	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
TLS3_k127_8316848_4	755732.Fluta_3169	8.215e-78	268.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,1HY7Y@117743|Flavobacteriia,2PAQY@246874|Cryomorphaceae	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
TLS3_k127_8316848_2	755732.Fluta_3168	9.263e-216	687.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1HXE7@117743|Flavobacteriia,2PB0U@246874|Cryomorphaceae	976|Bacteroidetes	S	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
TLS3_k127_8316848_6	755732.Fluta_3167	1.36e-71	246.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,1HWSC@117743|Flavobacteriia,2PAXP@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
TLS3_k127_8316848_9	762903.Pedsa_3680	2.16e-09	66.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,1IPC6@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
TLS3_k127_831926_0	1123248.KB893339_gene2712	4.62e-169	550.0	COG2373@1|root,COG3391@1|root,COG2373@2|Bacteria,COG3391@2|Bacteria,4NTMR@976|Bacteroidetes	976|Bacteroidetes	M	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3494
TLS3_k127_831926_5	880070.Cycma_1772	5.894e-11	65.0	2EFZF@1|root,339RM@2|Bacteria,4PBTK@976|Bacteroidetes,47WAY@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_831926_6	1492738.FEM21_28100	1.52e-09	60.0	COG4980@1|root,COG4980@2|Bacteria,4NRSE@976|Bacteroidetes,1I46Y@117743|Flavobacteriia,2NX2B@237|Flavobacterium	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
TLS3_k127_831926_7	1461577.CCMH01000037_gene137	5.329e-05	50.0	2AAKA@1|root,30ZXT@2|Bacteria,4PK63@976|Bacteroidetes,1I6V9@117743|Flavobacteriia	976|Bacteroidetes	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
TLS3_k127_831926_3	269798.CHU_2927	2.784e-92	316.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,47KDN@768503|Cytophagia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS3_k127_831926_1	1123248.KB893339_gene2712	9.521e-143	499.0	COG2373@1|root,COG3391@1|root,COG2373@2|Bacteria,COG3391@2|Bacteria,4NTMR@976|Bacteroidetes	976|Bacteroidetes	M	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3494
TLS3_k127_831926_4	398720.MED217_04732	1.752e-41	178.0	COG1361@1|root,COG2911@1|root,COG1361@2|Bacteria,COG2911@2|Bacteria,4NMB8@976|Bacteroidetes,1IJ89@117743|Flavobacteriia,2XJTW@283735|Leeuwenhoekiella	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,DUF11,SdrD_B
TLS3_k127_831926_2	755732.Fluta_2045	3.035e-102	341.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HWKC@117743|Flavobacteriia,2PBE9@246874|Cryomorphaceae	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
TLS3_k127_8329890_0	1123508.JH636439_gene1132	1.484e-96	329.0	COG1520@1|root,COG2373@1|root,COG2931@1|root,COG3386@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2J4W7@203682|Planctomycetes	2|Bacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,CHU_C,DUF11,DUF4347,SdrD_B
TLS3_k127_8329890_1	1168289.AJKI01000063_gene3522	4.473e-53	196.0	COG3279@1|root,COG3279@2|Bacteria,4NNHE@976|Bacteroidetes,2FY9U@200643|Bacteroidia,3XIXF@558415|Marinilabiliaceae	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
TLS3_k127_8335032_2	471854.Dfer_0542	1.255e-110	364.0	COG0513@1|root,COG0513@2|Bacteria,4NHCA@976|Bacteroidetes,47MGW@768503|Cytophagia	976|Bacteroidetes	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
TLS3_k127_8335032_4	755732.Fluta_2852	4.305e-93	311.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,1HX93@117743|Flavobacteriia,2PANE@246874|Cryomorphaceae	976|Bacteroidetes	S	zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
TLS3_k127_8335032_1	1346330.M472_05945	3.616e-139	451.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,1IP4G@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
TLS3_k127_8335032_6	755732.Fluta_1191	4.437e-29	126.0	2A95T@1|root,30YAC@2|Bacteria,4PC21@976|Bacteroidetes,1IMT5@117743|Flavobacteriia,2PC2Z@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8335032_0	755732.Fluta_1194	2.635e-209	670.0	COG1368@1|root,COG1368@2|Bacteria,4NIAA@976|Bacteroidetes,1HY17@117743|Flavobacteriia,2PBGU@246874|Cryomorphaceae	976|Bacteroidetes	M	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
TLS3_k127_8335032_3	755732.Fluta_1195	1.354e-101	338.0	COG1597@1|root,COG1597@2|Bacteria,4NJWB@976|Bacteroidetes,1HZF4@117743|Flavobacteriia,2PAU5@246874|Cryomorphaceae	976|Bacteroidetes	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
TLS3_k127_8335032_7	755732.Fluta_1196	1.141e-28	121.0	COG2030@1|root,COG2030@2|Bacteria,4NUTF@976|Bacteroidetes,1IB9P@117743|Flavobacteriia,2PBY4@246874|Cryomorphaceae	976|Bacteroidetes	I	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
TLS3_k127_8335032_5	755732.Fluta_1198	2.355e-41	162.0	COG2981@1|root,COG2981@2|Bacteria,4PCAY@976|Bacteroidetes,1ICT6@117743|Flavobacteriia,2PC2N@246874|Cryomorphaceae	976|Bacteroidetes	E	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	-
TLS3_k127_8350847_3	1358423.N180_01810	3.804e-14	77.0	2EGFG@1|root,33A7G@2|Bacteria,4PIVB@976|Bacteroidetes,1IYNR@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8350847_1	1123037.AUDE01000018_gene2866	1.714e-121	392.0	COG1814@1|root,COG1814@2|Bacteria,4NE6W@976|Bacteroidetes,1HZ1U@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
TLS3_k127_8350847_0	1121904.ARBP01000050_gene4431	1.332e-145	465.0	COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,4NFYC@976|Bacteroidetes,47K38@768503|Cytophagia	976|Bacteroidetes	K	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	ada	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18,Methyltransf_1N
TLS3_k127_8350847_2	313603.FB2170_15383	7.369e-100	328.0	COG3145@1|root,COG3145@2|Bacteria,4NFEG@976|Bacteroidetes,1HWRD@117743|Flavobacteriia,2PG7Z@252356|Maribacter	976|Bacteroidetes	L	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
TLS3_k127_8377084_9	1408433.JHXV01000007_gene2839	2.011e-72	251.0	COG2095@1|root,COG2095@2|Bacteria,4NIHF@976|Bacteroidetes,1HY3F@117743|Flavobacteriia,2PBD8@246874|Cryomorphaceae	976|Bacteroidetes	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
TLS3_k127_8377084_12	1286632.P278_00110	2.866e-56	208.0	COG3206@1|root,COG3206@2|Bacteria,4NP00@976|Bacteroidetes,1I22X@117743|Flavobacteriia	976|Bacteroidetes	M	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
TLS3_k127_8377084_16	1517682.HW49_07425	2.775e-07	53.0	29982@1|root,2ZWBD@2|Bacteria,4P96H@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8377084_11	755732.Fluta_3569	2.886e-62	216.0	COG1143@1|root,COG1143@2|Bacteria,4PKCQ@976|Bacteroidetes,1IJ7N@117743|Flavobacteriia,2PAUC@246874|Cryomorphaceae	976|Bacteroidetes	C	4Fe-4S binding domain	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
TLS3_k127_8377084_8	1408433.JHXV01000021_gene1663	1.643e-99	336.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,1HWNH@117743|Flavobacteriia,2PAQ4@246874|Cryomorphaceae	976|Bacteroidetes	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
TLS3_k127_8377084_0	755732.Fluta_3976	6.481e-307	955.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,1HXNJ@117743|Flavobacteriia,2PAJW@246874|Cryomorphaceae	976|Bacteroidetes	E	Peptidase S46	-	GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
TLS3_k127_8377084_1	755732.Fluta_3978	5.224e-286	910.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,2PBJE@246874|Cryomorphaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_92
TLS3_k127_8377084_6	755732.Fluta_3979	6.106e-119	391.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,1I0Z8@117743|Flavobacteriia,2PBMN@246874|Cryomorphaceae	976|Bacteroidetes	G	Glucokinase	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
TLS3_k127_8377084_10	573061.Clocel_0067	1.144e-65	230.0	COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,24FP5@186801|Clostridia,36FI2@31979|Clostridiaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
TLS3_k127_8377084_15	926556.Echvi_0868	6.341e-27	123.0	COG4447@1|root,COG4447@2|Bacteria,4NGUK@976|Bacteroidetes,47NCA@768503|Cytophagia	976|Bacteroidetes	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
TLS3_k127_8377084_7	755732.Fluta_3382	3.046e-109	364.0	COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,1HYHF@117743|Flavobacteriia,2PBEX@246874|Cryomorphaceae	976|Bacteroidetes	M	Bacterial lipid A biosynthesis acyltransferase	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
TLS3_k127_8377084_3	755732.Fluta_3383	5.32e-194	614.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1HXHG@117743|Flavobacteriia,2PAEJ@246874|Cryomorphaceae	976|Bacteroidetes	L	ATPase family associated with various cellular activities (AAA)	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
TLS3_k127_8377084_13	755732.Fluta_3384	4.495e-51	187.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,1HXJN@117743|Flavobacteriia,2PAZ7@246874|Cryomorphaceae	976|Bacteroidetes	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
TLS3_k127_8377084_2	755732.Fluta_3385	1.18e-240	770.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1HXS2@117743|Flavobacteriia,2PAME@246874|Cryomorphaceae	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8377084_4	755732.Fluta_3386	8.207e-149	480.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,1HX7G@117743|Flavobacteriia,2PAR3@246874|Cryomorphaceae	976|Bacteroidetes	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
TLS3_k127_8377084_5	755732.Fluta_3387	1.783e-127	416.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1HXN5@117743|Flavobacteriia,2PAY3@246874|Cryomorphaceae	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
TLS3_k127_8377084_14	755732.Fluta_3388	5.261e-29	118.0	COG0247@1|root,COG0247@2|Bacteria,4PM9R@976|Bacteroidetes,1IJNY@117743|Flavobacteriia,2PACW@246874|Cryomorphaceae	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
TLS3_k127_8402286_5	1313421.JHBV01000043_gene3209	4.029e-36	141.0	COG4067@1|root,COG4067@2|Bacteria,4NS86@976|Bacteroidetes,1IU9C@117747|Sphingobacteriia	976|Bacteroidetes	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
TLS3_k127_8402286_0	1121011.AUCB01000006_gene998	8.402e-144	460.0	COG0189@1|root,COG0189@2|Bacteria,4NED4@976|Bacteroidetes,1HZ04@117743|Flavobacteriia,23I6Q@178469|Arenibacter	976|Bacteroidetes	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
TLS3_k127_8402286_2	1124780.ANNU01000017_gene1899	5.646e-82	283.0	COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,47KEY@768503|Cytophagia	976|Bacteroidetes	S	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
TLS3_k127_8402286_6	1120965.AUBV01000007_gene2542	7.099e-21	93.0	COG3592@1|root,COG3592@2|Bacteria,4NVG3@976|Bacteroidetes	976|Bacteroidetes	S	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
TLS3_k127_8402286_3	1121101.HMPREF1532_03361	1.056e-41	169.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,2FNCU@200643|Bacteroidia,4AKZ6@815|Bacteroidaceae	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
TLS3_k127_8402286_4	1189612.A33Q_1333	3.109e-39	149.0	COG3682@1|root,COG3682@2|Bacteria,4NNVM@976|Bacteroidetes,47Q5Z@768503|Cytophagia	976|Bacteroidetes	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
TLS3_k127_8402286_7	1408433.JHXV01000005_gene2282	2.779e-20	93.0	2C565@1|root,32TAX@2|Bacteria,4NSKA@976|Bacteroidetes,1I4JX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8402286_9	865937.Gilli_0991	3.332e-11	68.0	2AVB5@1|root,31M2F@2|Bacteria,4NTAR@976|Bacteroidetes,1I3UY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8402286_1	755732.Fluta_2468	2.488e-115	376.0	COG0389@1|root,COG0389@2|Bacteria,4NF1Y@976|Bacteroidetes,1HXHJ@117743|Flavobacteriia,2PAAE@246874|Cryomorphaceae	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
TLS3_k127_8453014_5	755732.Fluta_0871	1.555e-110	368.0	COG1629@1|root,COG4771@2|Bacteria,4NE7A@976|Bacteroidetes,1IIH0@117743|Flavobacteriia,2PA5Q@246874|Cryomorphaceae	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,HMA,Plug,TonB_dep_Rec
TLS3_k127_8453014_9	755732.Fluta_0870	5.215e-30	124.0	COG2608@1|root,COG2608@2|Bacteria,4PFG3@976|Bacteroidetes,1IG5C@117743|Flavobacteriia,2PC1J@246874|Cryomorphaceae	976|Bacteroidetes	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
TLS3_k127_8453014_1	929703.KE386491_gene517	1.765e-237	738.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,47JW7@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
TLS3_k127_8453014_12	240016.ABIZ01000001_gene4878	9.82e-17	95.0	COG3209@1|root,COG3266@1|root,COG4782@1|root,COG3209@2|Bacteria,COG3266@2|Bacteria,COG4782@2|Bacteria,46S8F@74201|Verrucomicrobia,2IV48@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
TLS3_k127_8453014_8	1122179.KB890416_gene2728	1.622e-31	143.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
TLS3_k127_8453014_6	313596.RB2501_11632	1.568e-69	244.0	COG2834@1|root,COG2834@2|Bacteria,4NHV3@976|Bacteroidetes,1I15K@117743|Flavobacteriia	976|Bacteroidetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292,LolA_like
TLS3_k127_8453014_0	1237149.C900_02391	0.0	1444.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47P32@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
TLS3_k127_8453014_13	755732.Fluta_3357	6.814e-15	89.0	COG1357@1|root,COG1357@2|Bacteria,4PNZS@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
TLS3_k127_8453014_4	755732.Fluta_3858	2.006e-123	429.0	COG5306@1|root,COG5306@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	DUF2341,Laminin_G_3,PKD
TLS3_k127_8453014_3	1094466.KQS_05960	5.045e-132	431.0	COG1305@1|root,COG1305@2|Bacteria,4NGQ2@976|Bacteroidetes	976|Bacteroidetes	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,Transglut_core
TLS3_k127_8453014_10	485918.Cpin_7173	4.411e-29	136.0	COG2304@1|root,COG2304@2|Bacteria,4NIM2@976|Bacteroidetes,1IVPA@117747|Sphingobacteriia	976|Bacteroidetes	S	SMART von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
TLS3_k127_8453014_7	755732.Fluta_3341	2.538e-55	215.0	COG1470@1|root,COG3386@1|root,COG1470@2|Bacteria,COG3386@2|Bacteria,4PM1B@976|Bacteroidetes,1IKE7@117743|Flavobacteriia,2PC6R@246874|Cryomorphaceae	2|Bacteria	G	SPTR Cell surface protein	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	ASH,BNR_2,NPCBM_assoc,PEGA
TLS3_k127_8453014_14	67373.JOBF01000002_gene1249	1.967e-09	70.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,PD40,PQQ_2
TLS3_k127_8453014_11	1279009.ADICEAN_00428	5.496e-29	121.0	COG1073@1|root,COG1073@2|Bacteria,4NP3H@976|Bacteroidetes	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
TLS3_k127_845719_1	1239962.C943_00154	1.682e-72	245.0	2AKGE@1|root,31B89@2|Bacteria,4NQ22@976|Bacteroidetes,47UY0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_845719_0	755732.Fluta_1217	2.081e-185	604.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2PBDM@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
TLS3_k127_845719_2	755732.Fluta_3811	2.173e-56	200.0	COG0454@1|root,COG0456@2|Bacteria,4NP44@976|Bacteroidetes,1I196@117743|Flavobacteriia	976|Bacteroidetes	K	GCN5 family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
TLS3_k127_8463818_0	755732.Fluta_1407	5.39e-122	395.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1HX2X@117743|Flavobacteriia,2PA59@246874|Cryomorphaceae	976|Bacteroidetes	P	MgtE intracellular N domain	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
TLS3_k127_8463818_1	755732.Fluta_1420	6.291e-120	393.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1HXGX@117743|Flavobacteriia,2PAGW@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TLS3_k127_8463818_2	870187.Thini_2524	3.434e-118	386.0	COG1092@1|root,COG1092@2|Bacteria,1Q2BP@1224|Proteobacteria,1SJXH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltrans_SAM
TLS3_k127_8463818_3	755732.Fluta_1230	1.606e-59	210.0	28J86@1|root,2Z93E@2|Bacteria,4NJYR@976|Bacteroidetes,1I0EG@117743|Flavobacteriia,2PAYS@246874|Cryomorphaceae	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_849104_3	755732.Fluta_1812	1.572e-31	124.0	COG3536@1|root,COG3536@2|Bacteria,4PKQ9@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_849104_1	391603.FBALC1_10212	8.082e-114	385.0	2DBFJ@1|root,2Z8Z0@2|Bacteria,4PMR8@976|Bacteroidetes,1IJX5@117743|Flavobacteriia	976|Bacteroidetes	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
TLS3_k127_849104_0	755732.Fluta_1785	3.63e-227	711.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1HXD2@117743|Flavobacteriia,2PAKT@246874|Cryomorphaceae	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
TLS3_k127_849104_2	755732.Fluta_1786	1.042e-80	272.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1HX06@117743|Flavobacteriia,2PAF0@246874|Cryomorphaceae	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
TLS3_k127_8500162_1	1166018.FAES_3342	4.078e-24	108.0	COG2367@1|root,COG2367@2|Bacteria,4NH6K@976|Bacteroidetes,47K31@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
TLS3_k127_8500162_0	984262.SGRA_1268	3.978e-33	141.0	COG2340@1|root,COG2340@2|Bacteria,4NKR3@976|Bacteroidetes,1IWCU@117747|Sphingobacteriia	976|Bacteroidetes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,Colicin_V
TLS3_k127_8531040_0	755732.Fluta_2294	1.92e-258	812.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,1HWY2@117743|Flavobacteriia,2PBAG@246874|Cryomorphaceae	976|Bacteroidetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_8531040_1	755732.Fluta_2290	1.098e-167	546.0	28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,1HWV7@117743|Flavobacteriia,2PB05@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM gliding motility-associated protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
TLS3_k127_8531040_2	755732.Fluta_2291	8.65e-132	428.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,1HX8Y@117743|Flavobacteriia,2PAWJ@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM gliding motility associated protien GldN	gldN	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8536262_1	391587.KAOT1_01579	1.228e-223	713.0	COG1505@1|root,COG1505@2|Bacteria,4NM0V@976|Bacteroidetes,1I0XU@117743|Flavobacteriia	976|Bacteroidetes	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9,Peptidase_S9_N
TLS3_k127_8536262_4	1296415.JACC01000043_gene90	5.321e-55	196.0	COG3741@1|root,COG3741@2|Bacteria,4NR70@976|Bacteroidetes,1I3JH@117743|Flavobacteriia,2YJDI@290174|Aquimarina	976|Bacteroidetes	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8536262_0	1223410.KN050846_gene2791	2.069e-272	846.0	COG0659@1|root,COG0659@2|Bacteria,4NF1C@976|Bacteroidetes,1HX8C@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfate permease	ychM	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
TLS3_k127_8536262_5	1121007.AUML01000002_gene1647	1.116e-33	134.0	COG1278@1|root,COG1278@2|Bacteria,4NNNH@976|Bacteroidetes,1I1ZM@117743|Flavobacteriia,2YH9T@290174|Aquimarina	976|Bacteroidetes	K	Cold shock protein domain	cspG	-	-	-	-	-	-	-	-	-	-	-	CSD
TLS3_k127_8536262_6	641524.ADICYQ_1896	4.013e-23	99.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,47RX4@768503|Cytophagia	976|Bacteroidetes	K	Cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
TLS3_k127_8536262_2	388413.ALPR1_08353	3.749e-132	433.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47U5F@768503|Cytophagia	976|Bacteroidetes	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
TLS3_k127_8536262_3	1286632.P278_05190	1.109e-116	386.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1HX6Z@117743|Flavobacteriia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_8536262_7	926562.Oweho_0421	1.545e-19	97.0	2DTID@1|root,33KGU@2|Bacteria,4NZE6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8536262_8	1408473.JHXO01000011_gene3196	7.717e-11	63.0	2DQ2Z@1|root,334J0@2|Bacteria,4NZJS@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_854862_5	309807.SRU_2084	2.113e-07	60.0	COG3637@1|root,COG3637@2|Bacteria,4NSVH@976|Bacteroidetes,1FJGP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
TLS3_k127_854862_1	755732.Fluta_2322	9.139e-56	198.0	COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,1I23U@117743|Flavobacteriia,2PAX5@246874|Cryomorphaceae	976|Bacteroidetes	S	Phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PRA-PH
TLS3_k127_854862_3	929556.Solca_2089	3.631e-32	131.0	COG1051@1|root,COG1051@2|Bacteria,4NR5C@976|Bacteroidetes,1ISSM@117747|Sphingobacteriia	976|Bacteroidetes	F	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_854862_0	1408433.JHXV01000011_gene2039	3.309e-111	372.0	COG3675@1|root,COG3675@2|Bacteria,4PKPE@976|Bacteroidetes,1IKDT@117743|Flavobacteriia,2PBG3@246874|Cryomorphaceae	976|Bacteroidetes	I	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
TLS3_k127_854862_4	1408433.JHXV01000018_gene3807	7.14e-31	142.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_854862_2	1121373.KB903664_gene2559	3.397e-45	169.0	COG1694@1|root,COG1694@2|Bacteria,4NQ3H@976|Bacteroidetes,47QEV@768503|Cytophagia	976|Bacteroidetes	S	PFAM MazG nucleotide pyrophosphohydrolase	ypjD	-	-	-	-	-	-	-	-	-	-	-	MazG
TLS3_k127_8556807_0	927677.ALVU02000001_gene2624	1.647e-61	217.0	COG0546@1|root,COG0546@2|Bacteria,1G7X9@1117|Cyanobacteria	1117|Cyanobacteria	S	phosphoglycolate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
TLS3_k127_8556807_1	1123234.AUKI01000011_gene1173	0.0008605	49.0	2C1TV@1|root,3029P@2|Bacteria,4NPUR@976|Bacteroidetes,1I2FZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8556921_1	1121285.AUFK01000003_gene296	2.594e-84	286.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,1HY3U@117743|Flavobacteriia,3ZPD2@59732|Chryseobacterium	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
TLS3_k127_8556921_0	755732.Fluta_3406	2.69e-191	607.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1HXT7@117743|Flavobacteriia,2PANC@246874|Cryomorphaceae	976|Bacteroidetes	O	PDZ domain (Also known as DHR or GLGF)	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
TLS3_k127_8583311_2	1117318.PRUB_13216	4.413e-56	219.0	COG3422@1|root,COG3422@2|Bacteria,1P7SM@1224|Proteobacteria,1RQ75@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	protein of Photorhabdus and some similarities with	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8583311_6	56107.Cylst_4011	6.08e-05	53.0	COG4675@1|root,COG4675@2|Bacteria,1G8V2@1117|Cyanobacteria	1117|Cyanobacteria	S	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
TLS3_k127_8583311_0	1117318.PRUB_13226	1.455e-107	385.0	COG3299@1|root,COG3299@2|Bacteria,1MY5J@1224|Proteobacteria,1S324@1236|Gammaproteobacteria,2Q3R2@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	protein of Photorhabdus and some similarities with	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
TLS3_k127_8583311_5	1117318.PRUB_13231	1.075e-29	123.0	COG3628@1|root,COG3628@2|Bacteria,1N23A@1224|Proteobacteria,1SCDV@1236|Gammaproteobacteria,2Q3QM@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Gene 25-like lysozyme	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
TLS3_k127_8583311_3	1117318.PRUB_13236	7.181e-56	197.0	COG4104@1|root,COG4104@2|Bacteria,1RKQE@1224|Proteobacteria,1SAD9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PAAR motif	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
TLS3_k127_8583311_1	1117318.PRUB_13241	2.869e-85	301.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RZ3X@1236|Gammaproteobacteria,2Q3I8@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	protein and some similarities with VgrG protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
TLS3_k127_8583311_4	1117318.PRUB_13246	2.937e-43	162.0	COG1652@1|root,COG1652@2|Bacteria,1NB7R@1224|Proteobacteria,1SXPN@1236|Gammaproteobacteria,2Q3P0@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_882751_2	755732.Fluta_0028	1.122e-111	366.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,1HX58@117743|Flavobacteriia,2PAQA@246874|Cryomorphaceae	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
TLS3_k127_882751_1	1408433.JHXV01000012_gene3997	3.087e-150	478.0	COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,1HYEY@117743|Flavobacteriia,2PABF@246874|Cryomorphaceae	976|Bacteroidetes	I	Enoyl-(Acyl carrier protein) reductase	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_882751_0	755732.Fluta_0516	7.852e-281	872.0	COG0477@1|root,COG1674@1|root,COG0477@2|Bacteria,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1HXBM@117743|Flavobacteriia,2PAJ7@246874|Cryomorphaceae	976|Bacteroidetes	D	Ftsk_gamma	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
TLS3_k127_898475_3	755732.Fluta_3463	1.413e-66	237.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1HXJ6@117743|Flavobacteriia,2PAN4@246874|Cryomorphaceae	976|Bacteroidetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
TLS3_k127_898475_2	1408433.JHXV01000038_gene2219	3.041e-75	267.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,1IEBF@117743|Flavobacteriia,2PB0Z@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
TLS3_k127_898475_1	755732.Fluta_3461	5.562e-115	384.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,1HX3M@117743|Flavobacteriia,2PBBU@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
TLS3_k127_898475_0	1288963.ADIS_0011	3.104e-200	630.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,47KP9@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
TLS3_k127_898475_4	1122931.AUAE01000009_gene4898	2.468e-44	163.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,2FKZC@200643|Bacteroidia,22W92@171551|Porphyromonadaceae	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
TLS3_k127_908278_4	700598.Niako_3868	3.216e-50	197.0	COG3064@1|root,COG3064@2|Bacteria,4NNZ9@976|Bacteroidetes,1IV79@117747|Sphingobacteriia	976|Bacteroidetes	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_908278_2	1408433.JHXV01000022_gene3135	2.247e-81	302.0	COG3291@1|root,COG3291@2|Bacteria,4NRDH@976|Bacteroidetes,1IIK5@117743|Flavobacteriia,2PBFR@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
TLS3_k127_908278_5	1296415.JACC01000019_gene3774	2.518e-32	147.0	COG4932@1|root,COG5384@1|root,COG4932@2|Bacteria,COG5384@2|Bacteria,4PPVD@976|Bacteroidetes,1IKUY@117743|Flavobacteriia,2YM6R@290174|Aquimarina	976|Bacteroidetes	M	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_908278_0	1336803.PHEL49_1911	8.356e-302	929.0	COG0388@1|root,COG0388@2|Bacteria,4NEAQ@976|Bacteroidetes,1HWST@117743|Flavobacteriia,3VVZ8@52959|Polaribacter	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	ramA_2	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
TLS3_k127_908278_3	1123248.KB893339_gene2712	2.228e-56	214.0	COG2373@1|root,COG3391@1|root,COG2373@2|Bacteria,COG3391@2|Bacteria,4NTMR@976|Bacteroidetes	976|Bacteroidetes	M	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3494
TLS3_k127_908278_1	755732.Fluta_3728	3.255e-255	790.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HWXY@117743|Flavobacteriia	976|Bacteroidetes	Q	Multicopper oxidase	copA	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
TLS3_k127_957585_1	616991.JPOO01000003_gene2483	6.686e-284	873.0	COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,1I031@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
TLS3_k127_957585_2	1237149.C900_03516	2.739e-68	243.0	COG3509@1|root,COG4733@1|root,COG3509@2|Bacteria,COG4733@2|Bacteria,4NR4C@976|Bacteroidetes	976|Bacteroidetes	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
TLS3_k127_957585_0	755732.Fluta_3214	0.0	1289.0	COG1657@1|root,COG1657@2|Bacteria,4P1FF@976|Bacteroidetes,1I81H@117743|Flavobacteriia	976|Bacteroidetes	I	Squalene-hopene cyclase N-terminal domain	-	-	5.4.99.7	ko:K01852	ko00100,ko01100,ko01110,ko01130,map00100,map01100,map01110,map01130	M00101	R03199	RC00874	ko00000,ko00001,ko00002,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
TLS3_k127_957585_3	755732.Fluta_3215	3.004e-28	115.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1HWSU@117743|Flavobacteriia,2PAFW@246874|Cryomorphaceae	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
TLS3_k127_958526_2	1122179.KB890430_gene4307	2.081e-123	413.0	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,1IQIN@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
TLS3_k127_958526_0	760192.Halhy_6134	1.177e-148	486.0	COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,1IPWT@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
TLS3_k127_958526_7	1223410.KN050846_gene53	1.224e-21	104.0	2DS3S@1|root,33EDT@2|Bacteria,4NY8U@976|Bacteroidetes,1I70J@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_958526_1	755732.Fluta_1170	1.803e-137	454.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,1HXEV@117743|Flavobacteriia,2PAA1@246874|Cryomorphaceae	976|Bacteroidetes	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
TLS3_k127_958526_4	755732.Fluta_1169	3.395e-43	160.0	29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,1I1Z8@117743|Flavobacteriia,2PB6N@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_958526_6	1121904.ARBP01000013_gene320	2.516e-38	151.0	COG2353@1|root,COG2353@2|Bacteria,4NJX1@976|Bacteroidetes,47W3Z@768503|Cytophagia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_958526_5	1408433.JHXV01000002_gene461	1.382e-42	162.0	COG1286@1|root,COG1286@2|Bacteria,4NRG9@976|Bacteroidetes,1I2B6@117743|Flavobacteriia,2PB7N@246874|Cryomorphaceae	976|Bacteroidetes	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
TLS3_k127_958526_3	755732.Fluta_1223	4.602e-102	335.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1HXYP@117743|Flavobacteriia,2PA7D@246874|Cryomorphaceae	976|Bacteroidetes	EF	Phosphoribosyl synthetase-associated domain	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
TLS3_k127_960932_3	1408433.JHXV01000009_gene1363	1.942e-10	63.0	COG0596@1|root,COG0596@2|Bacteria,4PNUJ@976|Bacteroidetes,1I9ER@117743|Flavobacteriia,2PBQD@246874|Cryomorphaceae	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
TLS3_k127_960932_2	641524.ADICYQ_0238	1.508e-48	175.0	COG0393@1|root,COG0393@2|Bacteria,4NQGB@976|Bacteroidetes,47QED@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
TLS3_k127_960932_0	1408433.JHXV01000011_gene2006	0.0	1240.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1HXCU@117743|Flavobacteriia,2PAJE@246874|Cryomorphaceae	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
TLS3_k127_973196_2	755732.Fluta_1983	8.283e-52	186.0	COG2755@1|root,COG2755@2|Bacteria,4NHT6@976|Bacteroidetes,1HYAV@117743|Flavobacteriia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
TLS3_k127_973196_1	755732.Fluta_1982	3.406e-154	497.0	COG2755@1|root,COG2755@2|Bacteria,4NGW6@976|Bacteroidetes,1I0ZE@117743|Flavobacteriia	976|Bacteroidetes	E	LysM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2,LysM
TLS3_k127_973196_0	755732.Fluta_1981	5.023e-215	682.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia	976|Bacteroidetes	M	Membrane protein involved in D-alanine export	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
TLS3_k127_973196_3	1250005.PHEL85_2253	3.521e-31	124.0	COG0389@1|root,COG0389@2|Bacteria,4NF1Y@976|Bacteroidetes,1HXHJ@117743|Flavobacteriia,3VV9P@52959|Polaribacter	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
TLS3_k127_977736_8	755732.Fluta_2459	4.154e-46	171.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IMQK@117743|Flavobacteriia,2PBES@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
TLS3_k127_977736_0	755732.Fluta_2460	2.86e-172	548.0	COG2067@1|root,COG2067@2|Bacteria,4NE43@976|Bacteroidetes,1HZ3R@117743|Flavobacteriia,2PA70@246874|Cryomorphaceae	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_977736_6	755732.Fluta_2461	5.349e-69	243.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,1HZ4M@117743|Flavobacteriia,2PAW8@246874|Cryomorphaceae	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
TLS3_k127_977736_10	755732.Fluta_2462	1.569e-32	130.0	COG1828@1|root,COG1828@2|Bacteria,4NV1M@976|Bacteroidetes,1IB4Z@117743|Flavobacteriia,2PBZ3@246874|Cryomorphaceae	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine (FGAM) synthase	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
TLS3_k127_977736_11	459495.SPLC1_S081700	3.663e-23	114.0	COG1807@1|root,COG1807@2|Bacteria,1GR6P@1117|Cyanobacteria,1HAH3@1150|Oscillatoriales	1117|Cyanobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_977736_4	755732.Fluta_2464	4.215e-88	301.0	COG4372@1|root,COG4372@2|Bacteria,4PKE4@976|Bacteroidetes,1IKDW@117743|Flavobacteriia,2PBQB@246874|Cryomorphaceae	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_977736_9	755732.Fluta_2465	1.2e-32	130.0	COG0724@1|root,COG0724@2|Bacteria,4NT1J@976|Bacteroidetes,1I4VC@117743|Flavobacteriia	976|Bacteroidetes	S	RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
TLS3_k127_977736_2	755732.Fluta_2466	6.838e-131	421.0	COG1024@1|root,COG1024@2|Bacteria,4NEH4@976|Bacteroidetes,1HXB6@117743|Flavobacteriia,2PA9D@246874|Cryomorphaceae	976|Bacteroidetes	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
TLS3_k127_977736_5	755732.Fluta_2473	4.047e-73	250.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,1I170@117743|Flavobacteriia,2PAS9@246874|Cryomorphaceae	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
TLS3_k127_977736_7	755732.Fluta_2474	6.836e-57	200.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,1I21V@117743|Flavobacteriia,2PAUD@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
TLS3_k127_977736_3	755732.Fluta_2475	2.674e-121	397.0	COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,1HWUX@117743|Flavobacteriia,2PA67@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
TLS3_k127_977736_1	755732.Fluta_2476	4.222e-131	422.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,1HWYJ@117743|Flavobacteriia,2PATD@246874|Cryomorphaceae	976|Bacteroidetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
TLS3_k127_985669_0	755732.Fluta_1212	5.201e-153	497.0	COG1409@1|root,COG1409@2|Bacteria,4NGK2@976|Bacteroidetes,1I0BV@117743|Flavobacteriia	976|Bacteroidetes	M	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
## 3327 queries scanned
## Total time (seconds): 62.94771957397461
## Rate: 52.85 q/s