## Thu Oct 17 15:25:10 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/TLS3_bin.6.fa -m mmseqs --itype genome -o TLS3_bin.6 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/TLS3_bin.6 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
TLS3_k127_1001951_12	1120948.KB903243_gene2394	9.06e-14	76.0	2E29A@1|root,30QXH@2|Bacteria,2H74E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1001951_0	1463936.JOJI01000005_gene4032	2.775e-183	589.0	COG3044@1|root,COG3044@2|Bacteria,2GN91@201174|Actinobacteria	201174|Actinobacteria	T	ATPase of the ABC class	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
TLS3_k127_1001951_10	1120948.KB903229_gene5263	4.809e-37	146.0	COG1376@1|root,COG1376@2|Bacteria,2HB4R@201174|Actinobacteria,4E4DH@85010|Pseudonocardiales	201174|Actinobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
TLS3_k127_1001951_2	1394178.AWOO02000069_gene288	4.191e-128	424.0	COG3285@1|root,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4EG6G@85012|Streptosporangiales	201174|Actinobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
TLS3_k127_1001951_1	710685.MycrhN_5692	9.046e-166	559.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,233DM@1762|Mycobacteriaceae	201174|Actinobacteria	K	involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,Trans_reg_C
TLS3_k127_1001951_7	1380347.JNII01000007_gene477	4.946e-78	276.0	COG2890@1|root,COG2890@2|Bacteria,2GNC1@201174|Actinobacteria,4ETZV@85013|Frankiales	201174|Actinobacteria	J	Belongs to the protein N5-glutamine methyltransferase family	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
TLS3_k127_1001951_3	1120948.KB903244_gene2858	1.016e-116	394.0	COG3246@1|root,COG3246@2|Bacteria,2HQHC@201174|Actinobacteria,4E9AI@85010|Pseudonocardiales	201174|Actinobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
TLS3_k127_1001951_11	68170.KL590480_gene8615	9.118e-28	130.0	COG0684@1|root,COG0684@2|Bacteria,2I8VQ@201174|Actinobacteria,4E6Z4@85010|Pseudonocardiales	201174|Actinobacteria	H	Aldolase/RraA	-	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
TLS3_k127_1001951_6	1120948.KB903240_gene4102	3.006e-96	323.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4E398@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_1001951_5	1120948.KB903224_gene365	4.943e-102	346.0	COG2755@1|root,COG2755@2|Bacteria,2GNBP@201174|Actinobacteria,4DY5I@85010|Pseudonocardiales	201174|Actinobacteria	E	Lysophospholipase L1-like esterase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS3_k127_1001951_8	105420.BBPO01000025_gene7118	1.731e-54	207.0	COG0454@1|root,COG0454@2|Bacteria,2I3JR@201174|Actinobacteria,2NINI@228398|Streptacidiphilus	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
TLS3_k127_1001951_9	1120948.KB903218_gene1893	1.797e-47	178.0	COG3247@1|root,COG3247@2|Bacteria,2H3AT@201174|Actinobacteria,4E81J@85010|Pseudonocardiales	201174|Actinobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
TLS3_k127_1001951_4	1120948.KB903240_gene4087	2.291e-107	354.0	2B2J4@1|root,31V48@2|Bacteria,2IPFQ@201174|Actinobacteria,4EC3E@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1007924_2	1120948.KB903229_gene5357	1.399e-11	64.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4DYX6@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Uncharacterised conserved protein (DUF2342)	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
TLS3_k127_1007924_0	1287475.HMPREF1650_13605	2.608e-121	410.0	COG0037@1|root,COG0634@1|root,COG0037@2|Bacteria,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,22JN8@1653|Corynebacteriaceae	201174|Actinobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0003674,GO:0003824,GO:0004422,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0052657,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
TLS3_k127_1007924_1	1120948.KB903229_gene5360	5.596e-32	131.0	COG0845@1|root,COG0845@2|Bacteria,2H154@201174|Actinobacteria,4DZ36@85010|Pseudonocardiales	201174|Actinobacteria	M	HlyD family secretion protein	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS3_k127_1022079_5	1120948.KB903224_gene356	8.728e-41	153.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4DYGS@85010|Pseudonocardiales	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
TLS3_k127_1022079_3	1120948.KB903224_gene355	6.532e-50	202.0	2DF72@1|root,32U4U@2|Bacteria,2GIV4@201174|Actinobacteria,4E4FD@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1022079_0	1120948.KB903224_gene354	1.728e-134	449.0	COG1052@1|root,COG1052@2|Bacteria,2I2IC@201174|Actinobacteria,4E09H@85010|Pseudonocardiales	201174|Actinobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TLS3_k127_1022079_4	1122611.KB903952_gene6009	9.558e-47	187.0	COG3945@1|root,COG3945@2|Bacteria,2IC3R@201174|Actinobacteria,4EJH7@85012|Streptosporangiales	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
TLS3_k127_1022079_1	1120948.KB903224_gene353	1.692e-124	416.0	COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria,4DYMA@85010|Pseudonocardiales	201174|Actinobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
TLS3_k127_1022079_2	1120948.KB903224_gene350	3.607e-91	304.0	COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria,4DYMA@85010|Pseudonocardiales	201174|Actinobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
TLS3_k127_1022855_2	1120948.KB903218_gene2188	9.669e-110	356.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4DZ3J@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the pyruvate kinase family	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
TLS3_k127_1022855_1	1120948.KB903218_gene2189	5.766e-176	561.0	COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria,4E1BH@85010|Pseudonocardiales	201174|Actinobacteria	E	Aminotransferase class I and II	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_1022855_3	1206733.BAGC01000041_gene1980	1.596e-18	89.0	2EP2A@1|root,33GP5@2|Bacteria,2HIUK@201174|Actinobacteria,4G4SR@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1022855_0	55952.BU52_07665	5.716e-257	811.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
TLS3_k127_1025151_0	1120948.KB903218_gene1926	1.996e-176	557.0	COG3239@1|root,COG3239@2|Bacteria,2GIWV@201174|Actinobacteria,4DZNV@85010|Pseudonocardiales	201174|Actinobacteria	C	Rubredoxin	alkB	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase,Rubredoxin
TLS3_k127_1025151_5	2074.JNYD01000007_gene1954	3.701e-117	405.0	COG0477@1|root,COG0477@2|Bacteria,2GKVX@201174|Actinobacteria,4E2A8@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_1025151_7	1120948.KB903234_gene4747	6.472e-68	234.0	COG3467@1|root,COG3467@2|Bacteria,2IIWQ@201174|Actinobacteria,4E4Z7@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
TLS3_k127_1025151_4	994479.GL877881_gene6508	5.943e-131	427.0	COG0031@1|root,COG0031@2|Bacteria,2GK6J@201174|Actinobacteria,4DXJE@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	-	2.5.1.140	ko:K21949	-	-	R11705	-	ko00000,ko01000	-	-	-	PALP
TLS3_k127_1025151_6	882083.SacmaDRAFT_4869	8.271e-110	388.0	COG4264@1|root,COG4264@2|Bacteria	882083.SacmaDRAFT_4869|-	Q	IucA IucC family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1025151_1	43354.JOIJ01000007_gene1645	1.358e-153	508.0	COG4264@1|root,COG4264@2|Bacteria,2GMS0@201174|Actinobacteria,4DY87@85010|Pseudonocardiales	201174|Actinobacteria	Q	IucA / IucC family	iucC	-	6.3.2.39	ko:K03895	ko00310,ko01120,map00310,map01120	-	R10091	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_8,FhuF,IucA_IucC
TLS3_k127_1025151_2	2074.JNYD01000007_gene1951	3.026e-136	447.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4DZPV@85010|Pseudonocardiales	201174|Actinobacteria	C	pfam fad	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
TLS3_k127_1025151_3	675635.Psed_1465	2.871e-134	441.0	COG2197@1|root,COG2197@2|Bacteria,2IATK@201174|Actinobacteria,4E4QW@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
TLS3_k127_1033000_1	1172179.AUKV01000001_gene979	8.702e-138	444.0	COG1028@1|root,COG1028@2|Bacteria,2GJVU@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_1033000_0	1120948.KB903246_gene3214	6.114e-239	745.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4E28W@85010|Pseudonocardiales	201174|Actinobacteria	E	Peptidase family M20/M25/M40	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_1049200_3	1120948.KB903231_gene4732	2.704e-106	357.0	COG5401@1|root,COG5401@2|Bacteria,2GJ5Y@201174|Actinobacteria,4DYNE@85010|Pseudonocardiales	201174|Actinobacteria	S	Lipoprotein LpqB beta-propeller domain	lpqB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Germane,Gmad1
TLS3_k127_1049200_0	675635.Psed_5183	2.815e-186	601.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2GJ2D@201174|Actinobacteria,4E174@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	mtrB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.7.13.3	ko:K07636,ko:K07654	ko02020,map02020	M00434,M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_1049200_1	1120948.KB903231_gene4734	9.977e-134	427.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4DXWN@85010|Pseudonocardiales	201174|Actinobacteria	KT	Response regulator receiver	mtrA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_1049200_4	1120948.KB903231_gene4735	1.669e-76	263.0	COG0125@1|root,COG0125@2|Bacteria,2HKRE@201174|Actinobacteria,4E2SW@85010|Pseudonocardiales	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
TLS3_k127_1049200_2	1120948.KB903231_gene4736	9.52e-125	400.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4DXX6@85010|Pseudonocardiales	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
TLS3_k127_1049379_2	1120948.KB903245_gene3702	1.481e-31	125.0	2EBHS@1|root,335I7@2|Bacteria,2IE9J@201174|Actinobacteria,4EBTI@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1049379_1	1120948.KB903244_gene3059	9.782e-106	348.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4DYC5@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2773c	DapB_C,DapB_N
TLS3_k127_1049379_0	1120948.KB903244_gene3060	2.507e-148	477.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4E16P@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the peptidase M16 family	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_1069597_1	1120948.KB903246_gene3379	1.487e-131	426.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4DYTK@85010|Pseudonocardiales	201174|Actinobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
TLS3_k127_1069597_2	1120948.KB903246_gene3380	2.762e-18	89.0	2EPYK@1|root,33HJ6@2|Bacteria,2GRIQ@201174|Actinobacteria,4E6NS@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1069597_0	1120948.KB903246_gene3381	5.112e-160	510.0	COG2120@1|root,COG2120@2|Bacteria,2H2NY@201174|Actinobacteria,4DYKF@85010|Pseudonocardiales	201174|Actinobacteria	S	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics	mca	GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
TLS3_k127_1069597_3	1120948.KB903246_gene3382	0.0006535	49.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4E353@85010|Pseudonocardiales	201174|Actinobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
TLS3_k127_107716_3	37919.EP51_07240	3.001e-91	305.0	2AEJC@1|root,314EV@2|Bacteria,2GMTI@201174|Actinobacteria,4FYTX@85025|Nocardiaceae	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
TLS3_k127_107716_4	1116232.AHBF01000068_gene8903	8.333e-10	64.0	COG1733@1|root,COG1733@2|Bacteria,2IQWP@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
TLS3_k127_107716_0	1123023.JIAI01000005_gene917	7.527e-253	801.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4DYVW@85010|Pseudonocardiales	201174|Actinobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
TLS3_k127_107716_1	675635.Psed_1809	6.277e-184	591.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4DXCF@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
TLS3_k127_107716_2	680198.SCAB_4581	2.018e-124	404.0	COG2267@1|root,COG2267@2|Bacteria,2GISG@201174|Actinobacteria	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
TLS3_k127_1088750_8	2074.JNYD01000011_gene140	1.227e-07	62.0	COG0589@1|root,COG2905@1|root,COG0589@2|Bacteria,COG2905@2|Bacteria,2I3QN@201174|Actinobacteria,4EF69@85010|Pseudonocardiales	201174|Actinobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS,Usp
TLS3_k127_1088750_9	2074.JNYD01000003_gene3952	0.0001123	54.0	COG0517@1|root,COG0517@2|Bacteria,2H0MS@201174|Actinobacteria,4E7ZB@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
TLS3_k127_1088750_5	1448389.BAVQ01000003_gene3509	9.5e-27	123.0	arCOG10456@1|root,2ZA6T@2|Bacteria,2IIHU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1088750_7	1246445.ANAY01000039_gene757	8.213e-13	79.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4EPN2@85012|Streptosporangiales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_1088750_3	1123024.AUII01000005_gene2461	3.996e-49	181.0	COG0716@1|root,COG0716@2|Bacteria,2IQZD@201174|Actinobacteria,4E5JA@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Flavodoxin	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_1,Flavodoxin_5
TLS3_k127_1088750_6	1370125.AUWT01000017_gene2263	4.249e-15	87.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,237XD@1762|Mycobacteriaceae	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_1088750_4	1120948.KB903247_gene4456	4.028e-33	134.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria,4E5WF@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1088750_0	1123024.AUII01000012_gene4118	6.419e-65	234.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4E2RP@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_1088750_10	1122611.KB903956_gene119	0.0001171	48.0	COG1846@1|root,COG1846@2|Bacteria,2IMGG@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_24,MarR_2
TLS3_k127_1088750_2	235985.BBPN01000045_gene8062	4.581e-52	194.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria,2NIW2@228398|Streptacidiphilus	201174|Actinobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
TLS3_k127_1092185_0	208444.JNYY01000011_gene2935	4.514e-218	687.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4E23I@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase Ligase (LigD)	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
TLS3_k127_1092185_5	1120948.KB903217_gene968	7.424e-94	318.0	COG1414@1|root,COG1414@2|Bacteria,2I9RP@201174|Actinobacteria,4E355@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
TLS3_k127_1092185_2	1068978.AMETH_2742	1.653e-144	464.0	COG1018@1|root,COG1018@2|Bacteria,2GJCV@201174|Actinobacteria,4DYA2@85010|Pseudonocardiales	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
TLS3_k127_1092185_1	1394178.AWOO02000074_gene2235	1.617e-193	610.0	COG2124@1|root,COG2124@2|Bacteria,2HCZN@201174|Actinobacteria,4EMVH@85012|Streptosporangiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	1.14.13.141	ko:K15981	ko00984,ko01120,map00984,map01120	-	R09859,R11357	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
TLS3_k127_1092185_4	1120948.KB903218_gene1863	1.04e-112	371.0	COG0697@1|root,COG0697@2|Bacteria,2GRXH@201174|Actinobacteria,4E5AF@85010|Pseudonocardiales	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1092185_6	1179773.BN6_55970	4.484e-40	170.0	COG2207@1|root,COG2207@2|Bacteria,2IE94@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
TLS3_k127_1092185_3	680198.SCAB_4581	4.181e-125	406.0	COG2267@1|root,COG2267@2|Bacteria,2GISG@201174|Actinobacteria	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
TLS3_k127_1092185_7	2074.JNYD01000003_gene3880	1.327e-35	137.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4DXCF@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
TLS3_k127_1097029_0	1120948.KB903240_gene3968	6.674e-267	834.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4DXE0@85010|Pseudonocardiales	201174|Actinobacteria	C	Malic enzyme, NAD binding domain	maeA	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
TLS3_k127_1097029_9	1120948.KB903219_gene643	1.406e-111	365.0	COG2120@1|root,COG2120@2|Bacteria,2GIUS@201174|Actinobacteria,4DZX7@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	rifO	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TLS3_k127_1097029_3	1120948.KB903219_gene641	1.636e-208	670.0	COG2230@1|root,COG2230@2|Bacteria,2GM5H@201174|Actinobacteria,4DYVX@85010|Pseudonocardiales	201174|Actinobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
TLS3_k127_1097029_8	1120948.KB903219_gene640	2.709e-126	409.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria,4DX8W@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_1097029_1	1120948.KB903219_gene639	3.027e-238	757.0	COG2251@1|root,COG2251@2|Bacteria,2HF5B@201174|Actinobacteria,4E083@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM RecB family nuclease	-	-	-	-	-	-	-	-	-	-	-	-	RNase_H_2
TLS3_k127_1097029_16	1120948.KB903219_gene638	1.43e-44	181.0	2E45H@1|root,32Z1I@2|Bacteria,2GN4U@201174|Actinobacteria,4E57T@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1097029_11	1120948.KB903219_gene637	1.356e-106	355.0	COG1414@1|root,COG1414@2|Bacteria,2IDTU@201174|Actinobacteria,4EEQV@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional regulator	-	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR,MarR_2
TLS3_k127_1097029_12	1120948.KB903219_gene636	2.362e-94	319.0	COG1174@1|root,COG1174@2|Bacteria,2GMQT@201174|Actinobacteria,4DXYP@85010|Pseudonocardiales	201174|Actinobacteria	E	ABC-type proline glycine betaine transport system, permease component	opuBB_3	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
TLS3_k127_1097029_4	1120948.KB903219_gene635	5.445e-198	621.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,4DY7Y@85010|Pseudonocardiales	201174|Actinobacteria	E	glycine betaine	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,BPD_transp_1,CBS
TLS3_k127_1097029_13	1120948.KB903219_gene634	2.078e-90	321.0	COG1174@1|root,COG1174@2|Bacteria,2H9I7@201174|Actinobacteria,4DYIG@85010|Pseudonocardiales	201174|Actinobacteria	E	ABC-type proline glycine betaine transport system, permease component	opuBB	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
TLS3_k127_1097029_6	1120948.KB903219_gene633	5.339e-147	473.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4DXIG@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
TLS3_k127_1097029_7	1120948.KB903219_gene632	1.594e-129	422.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4DXIG@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
TLS3_k127_1097029_15	1120948.KB903219_gene631	1.281e-57	213.0	COG1732@1|root,COG1732@2|Bacteria	2|Bacteria	M	glycine betaine transport	yehZ	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
TLS3_k127_1097029_14	675635.Psed_0135	1.985e-73	253.0	COG0702@1|root,COG0702@2|Bacteria,2GKNN@201174|Actinobacteria,4E314@85010|Pseudonocardiales	201174|Actinobacteria	GM	NAD dependent epimerase dehydratase family	yhfK	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
TLS3_k127_1097029_5	345341.KUTG_01741	6.977e-158	506.0	COG1064@1|root,COG1064@2|Bacteria,2GKNW@201174|Actinobacteria,4DXG6@85010|Pseudonocardiales	201174|Actinobacteria	S	alcohol dehydrogenase	-	-	-	ko:K18382	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_1097029_2	1120948.KB903219_gene628	3.183e-211	659.0	COG2159@1|root,COG2159@2|Bacteria,2I9CM@201174|Actinobacteria,4E0SZ@85010|Pseudonocardiales	201174|Actinobacteria	S	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
TLS3_k127_1097029_10	1120948.KB903219_gene627	4.198e-110	372.0	COG2151@1|root,COG2151@2|Bacteria,2IAEQ@201174|Actinobacteria,4E453@85010|Pseudonocardiales	201174|Actinobacteria	S	metal-sulfur cluster biosynthetic enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
TLS3_k127_110515_1	1120948.KB903248_gene4357	2.249e-236	732.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4DXYJ@85010|Pseudonocardiales	201174|Actinobacteria	E	glutamine synthetase	glnA2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
TLS3_k127_110515_3	390989.JOEG01000006_gene739	2.167e-79	279.0	COG2807@1|root,COG2807@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_110515_0	1123023.JIAI01000002_gene5139	0.0	1283.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria,4DZJZ@85010|Pseudonocardiales	201174|Actinobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
TLS3_k127_110515_4	1120948.KB903217_gene1488	3.779e-70	240.0	COG3795@1|root,COG3795@2|Bacteria,2IFD6@201174|Actinobacteria,4E2TW@85010|Pseudonocardiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
TLS3_k127_110515_2	1120950.KB892746_gene3457	1.269e-188	643.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DP3H@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_110515_5	1120948.KB903248_gene4353	2.111e-54	193.0	2DC3S@1|root,2ZCSP@2|Bacteria,2GZ8E@201174|Actinobacteria,4E828@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1127668_1	1120948.KB903245_gene3512	2.337e-88	294.0	COG1414@1|root,COG1414@2|Bacteria,2GKB0@201174|Actinobacteria,4DZ11@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	ltbR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
TLS3_k127_1127668_3	1120948.KB903224_gene366	1.759e-30	133.0	2AVNR@1|root,31MFR@2|Bacteria,2HBMC@201174|Actinobacteria	1120948.KB903224_gene366|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1127668_2	1120948.KB903229_gene5079	1.676e-42	162.0	COG2119@1|root,COG2119@2|Bacteria,2GNR0@201174|Actinobacteria,4E2WC@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
TLS3_k127_1127668_4	1298860.AUEM01000005_gene2736	0.0003509	52.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TLS3_k127_1127668_0	1120948.KB903245_gene3517	0.0	1188.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4DX9G@85010|Pseudonocardiales	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
TLS3_k127_1143132_1	1120948.KB903217_gene1603	1.974e-58	213.0	2DVAJ@1|root,33V1E@2|Bacteria,2GS36@201174|Actinobacteria,4E3BY@85010|Pseudonocardiales	201174|Actinobacteria	S	Anti-sigma-D factor RsdA to sigma factor binding region	rsdA	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	RsdA_SigD_bd
TLS3_k127_1143132_0	1120948.KB903217_gene1602	3.86e-101	333.0	COG1595@1|root,COG1595@2|Bacteria,2GM8T@201174|Actinobacteria,4DY2F@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS3_k127_1147633_6	33898.JRHJ01000055_gene5916	1.723e-38	152.0	COG0500@1|root,COG2226@2|Bacteria,2IHWE@201174|Actinobacteria	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_1147633_3	518766.Rmar_2202	1.837e-141	468.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,1FJSN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IQ	AMP-binding enzyme C-terminal domain	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
TLS3_k127_1147633_1	1123024.AUII01000022_gene129	2.137e-179	619.0	COG2197@1|root,COG2197@2|Bacteria,2I321@201174|Actinobacteria,4EF7G@85010|Pseudonocardiales	201174|Actinobacteria	KT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_1147633_2	1206731.BAGB01000169_gene1511	2.373e-175	556.0	COG0500@1|root,COG0500@2|Bacteria,2I3GX@201174|Actinobacteria,4G9Z4@85025|Nocardiaceae	201174|Actinobacteria	Q	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
TLS3_k127_1147633_0	1120949.KB903357_gene4935	5.3e-231	768.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2IDNX@201174|Actinobacteria	201174|Actinobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
TLS3_k127_1147633_7	196162.Noca_4927	7.951e-25	113.0	COG3832@1|root,COG3832@2|Bacteria,2IQXG@201174|Actinobacteria,4DVDI@85009|Propionibacteriales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_1147633_5	526225.Gobs_4432	4.414e-45	174.0	COG4319@1|root,COG4319@2|Bacteria,2IHRK@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
TLS3_k127_1147633_4	1120948.KB903243_gene2553	1.136e-82	277.0	COG2141@1|root,COG2141@2|Bacteria,2GKHN@201174|Actinobacteria,4DXPU@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	sfnG	-	1.14.14.35	ko:K17228	ko00920,map00920	-	R10203	RC02556,RC03080	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
TLS3_k127_1152424_0	2074.JNYD01000061_gene5394	4.536e-265	821.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,2GMBK@201174|Actinobacteria,4E081@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the GcvT family	soxA	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2,SoxD
TLS3_k127_1152424_1	1120948.KB903244_gene2825	3.295e-23	104.0	COG4583@1|root,COG4583@2|Bacteria,2HJE7@201174|Actinobacteria,4E4X2@85010|Pseudonocardiales	201174|Actinobacteria	E	Sarcosine oxidase, gamma subunit family	soxG	-	1.5.3.1	ko:K00305	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxG
TLS3_k127_1155001_1	1120948.KB903243_gene2354	3.14e-160	516.0	28KB1@1|root,2Z9Y5@2|Bacteria,2GM37@201174|Actinobacteria,4DXBX@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1155001_0	1120948.KB903243_gene2353	3.925e-196	617.0	COG0451@1|root,COG0451@2|Bacteria,2GK8K@201174|Actinobacteria,4DZDM@85010|Pseudonocardiales	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	galE3	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
TLS3_k127_1155001_2	1120948.KB903243_gene2352	1.536e-47	174.0	COG0521@1|root,COG0521@2|Bacteria,2IACJ@201174|Actinobacteria,4E2MX@85010|Pseudonocardiales	201174|Actinobacteria	H	molybdenum cofactor	moaB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	MoCF_biosynth
TLS3_k127_1159376_0	1120948.KB903246_gene3407	9.342e-201	636.0	COG0477@1|root,COG2814@2|Bacteria,2GKRT@201174|Actinobacteria,4DX93@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_1159376_2	1120948.KB903246_gene3408	2.154e-32	138.0	2EMAJ@1|root,33EZJ@2|Bacteria,2IRTV@201174|Actinobacteria,4E6BI@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2771)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2771
TLS3_k127_1159376_3	1449355.JQNR01000005_gene5778	1.853e-06	60.0	COG3534@1|root,COG5520@1|root,COG3534@2|Bacteria,COG5520@2|Bacteria,2I32Z@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl hydrolase family 59	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_59,Laminin_G_3,RicinB_lectin_2,Ricin_B_lectin
TLS3_k127_1159376_1	883126.HMPREF9710_02800	2.576e-78	279.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Lipase_GDSL_2
TLS3_k127_1166203_2	1120948.KB903227_gene4900	4.084e-21	108.0	COG2207@1|root,COG2207@2|Bacteria,2IBP1@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
TLS3_k127_1166203_3	1120948.KB903227_gene4901	4.792e-10	65.0	COG1352@1|root,COG1352@2|Bacteria,2HHZ1@201174|Actinobacteria,4E0R1@85010|Pseudonocardiales	201174|Actinobacteria	NT	Methyltransferase, chemotaxis proteins	cheR	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheR,CheR_N,PAS,PAS_4,PAS_9
TLS3_k127_1166203_0	1120948.KB903224_gene371	1.893e-138	446.0	COG3396@1|root,COG3396@2|Bacteria,2GMBI@201174|Actinobacteria,4DYYP@85010|Pseudonocardiales	201174|Actinobacteria	S	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
TLS3_k127_1166203_1	1089545.KB913037_gene610	4.307e-22	98.0	COG1309@1|root,COG1309@2|Bacteria,2IIZX@201174|Actinobacteria,4E5QV@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_119038_2	1120948.KB903244_gene2935	3.954e-77	272.0	2AR9G@1|root,31GJC@2|Bacteria,2GN9V@201174|Actinobacteria,4E2Q7@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4192)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4192
TLS3_k127_119038_0	1120948.KB903244_gene2933	4.025e-149	479.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,4DXKF@85010|Pseudonocardiales	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
TLS3_k127_119038_1	1120948.KB903244_gene2932	9.517e-129	413.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria,4DXCH@85010|Pseudonocardiales	201174|Actinobacteria	K	iron dependent repressor	ideR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
TLS3_k127_1191126_1	1394178.AWOO02000007_gene3068	5.373e-87	296.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4EP4I@85012|Streptosporangiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_1191126_4	477641.MODMU_5406	2.077e-28	129.0	2DNC4@1|root,32WQC@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3224)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3224
TLS3_k127_1191126_3	469383.Cwoe_1969	3.262e-46	178.0	COG1764@1|root,COG1764@2|Bacteria,2IHT2@201174|Actinobacteria,4CT3G@84995|Rubrobacteria	84995|Rubrobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
TLS3_k127_1191126_0	675635.Psed_1463	0.0	1360.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,2GKBW@201174|Actinobacteria,4E0GX@85010|Pseudonocardiales	201174|Actinobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K00179,ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR,POR_N,TPP_enzyme_C
TLS3_k127_1191126_2	1120948.KB903229_gene5132	1.727e-60	241.0	COG1522@1|root,COG1522@2|Bacteria,2H7NM@201174|Actinobacteria,4E2QD@85010|Pseudonocardiales	201174|Actinobacteria	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
TLS3_k127_1191709_8	1120948.KB903229_gene5207	4.227e-25	120.0	COG0671@1|root,COG0671@2|Bacteria,2HIXE@201174|Actinobacteria,4E088@85010|Pseudonocardiales	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
TLS3_k127_1191709_7	1125971.ASJB01000080_gene7302	1.998e-40	158.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
TLS3_k127_1191709_10	1068978.AMETH_5582	0.0004802	52.0	COG1525@1|root,COG1525@2|Bacteria,2I5D6@201174|Actinobacteria,4EDUW@85010|Pseudonocardiales	201174|Actinobacteria	L	Excalibur calcium-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Excalibur
TLS3_k127_1191709_3	996637.SGM_2955	1.33e-73	258.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
TLS3_k127_1191709_9	1068978.AMETH_5582	2.398e-10	70.0	COG1525@1|root,COG1525@2|Bacteria,2I5D6@201174|Actinobacteria,4EDUW@85010|Pseudonocardiales	201174|Actinobacteria	L	Excalibur calcium-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Excalibur
TLS3_k127_1191709_6	1068978.AMETH_5583	2.825e-44	173.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria,4E51P@85010|Pseudonocardiales	201174|Actinobacteria	M	Sortase (surface protein transpeptidase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
TLS3_k127_1191709_0	1120948.KB903229_gene5205	1.207e-234	779.0	COG1807@1|root,COG1807@2|Bacteria,2GJPU@201174|Actinobacteria,4EAEB@85010|Pseudonocardiales	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_1191709_1	1120948.KB903229_gene5204	6.965e-194	618.0	COG1215@1|root,COG1215@2|Bacteria,2GJTE@201174|Actinobacteria,4DYC7@85010|Pseudonocardiales	201174|Actinobacteria	M	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
TLS3_k127_1191709_2	1120948.KB903229_gene4982	6.495e-84	289.0	COG2267@1|root,COG2267@2|Bacteria,2GMY4@201174|Actinobacteria,4E4CB@85010|Pseudonocardiales	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
TLS3_k127_1191709_4	1828.JOKB01000007_gene2710	5.156e-66	255.0	COG0262@1|root,COG0262@2|Bacteria,2GK32@201174|Actinobacteria,4G3AR@85025|Nocardiaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
TLS3_k127_1191709_5	1120948.KB903229_gene5203	4.306e-61	223.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4DXXX@85010|Pseudonocardiales	201174|Actinobacteria	O	PDZ domain (Also known as DHR or GLGF)	pepD	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
TLS3_k127_1209762_5	1120948.KB903220_gene90	3.271e-75	256.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria,4E3UG@85010|Pseudonocardiales	201174|Actinobacteria	S	Isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
TLS3_k127_1209762_0	1120948.KB903220_gene86	2.879e-232	734.0	COG1807@1|root,COG1807@2|Bacteria,2GNPY@201174|Actinobacteria,4E1MR@85010|Pseudonocardiales	201174|Actinobacteria	M	capsule polysaccharide biosynthetic process	aftB	GO:0008150,GO:0040007	-	ko:K13687	-	-	-	-	ko00000,ko01000,ko01003	-	GT89	-	-
TLS3_k127_1209762_2	103733.JNYO01000002_gene503	3.267e-152	509.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,4DX5U@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
TLS3_k127_1209762_4	1120948.KB903220_gene84	6.144e-89	314.0	COG1434@1|root,COG1434@2|Bacteria,2I2NF@201174|Actinobacteria,4E2P9@85010|Pseudonocardiales	201174|Actinobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
TLS3_k127_1209762_3	1120948.KB903220_gene83	1.315e-114	379.0	COG1975@1|root,COG1975@2|Bacteria,2I8ZS@201174|Actinobacteria,4E9UH@85010|Pseudonocardiales	201174|Actinobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
TLS3_k127_1209762_1	1120948.KB903220_gene82	1.705e-161	509.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4DXGM@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
TLS3_k127_1257100_2	1120948.KB903217_gene1057	1.109e-127	412.0	COG5297@1|root,COG5297@2|Bacteria,2GK39@201174|Actinobacteria,4DYZF@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Glyco_hydro_6
TLS3_k127_1257100_3	649831.L083_1720	1.134e-114	376.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4DFH6@85008|Micromonosporales	201174|Actinobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
TLS3_k127_1257100_4	749927.AMED_9241	5.898e-93	311.0	COG2128@1|root,COG2128@2|Bacteria,2GM9D@201174|Actinobacteria,4DYVH@85010|Pseudonocardiales	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
TLS3_k127_1257100_6	1120948.KB903217_gene1061	1.486e-54	197.0	2DSMY@1|root,33GQS@2|Bacteria,2GVW6@201174|Actinobacteria,4E7K8@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3024)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3024
TLS3_k127_1257100_5	1120948.KB903217_gene1062	1.863e-80	289.0	COG0494@1|root,COG0494@2|Bacteria,2II41@201174|Actinobacteria,4E3KS@85010|Pseudonocardiales	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_1257100_0	1120948.KB903217_gene1063	2.534e-281	874.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4E8WI@85010|Pseudonocardiales	201174|Actinobacteria	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS3_k127_1257100_1	1120948.KB903217_gene1064	4.727e-133	434.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4DZ9X@85010|Pseudonocardiales	201174|Actinobacteria	S	Aldo keto	dkgA	-	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
TLS3_k127_1260751_1	1120948.KB903217_gene1468	7.857e-35	140.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4DYYM@85010|Pseudonocardiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TLS3_k127_1260751_0	1120948.KB903217_gene1467	7.578e-207	652.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4E05T@85010|Pseudonocardiales	201174|Actinobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TLS3_k127_1309725_3	1120948.KB903222_gene582	2.583e-70	239.0	COG0110@1|root,COG1020@1|root,COG0110@2|Bacteria,COG1020@2|Bacteria,2I8TI@201174|Actinobacteria,4E1Y1@85010|Pseudonocardiales	201174|Actinobacteria	Q	Phosphopantetheine attachment site	nrps4	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Hexapep,Hexapep_2,PP-binding
TLS3_k127_1309725_0	1120948.KB903222_gene581	0.0	1057.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4DXHP@85010|Pseudonocardiales	201174|Actinobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
TLS3_k127_1309725_1	1120948.KB903222_gene580	7.151e-170	550.0	COG2423@1|root,COG2423@2|Bacteria,2H4D8@201174|Actinobacteria,4E0KD@85010|Pseudonocardiales	201174|Actinobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	ocd	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
TLS3_k127_1309725_4	318424.EU78_04450	8.13e-49	186.0	COG1716@1|root,COG1716@2|Bacteria,2HPF7@201174|Actinobacteria,2351W@1762|Mycobacteriaceae	201174|Actinobacteria	T	Fha domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,FHA
TLS3_k127_1309725_2	1380356.JNIK01000016_gene3595	3.943e-82	296.0	COG0515@1|root,COG0515@2|Bacteria,2I6W6@201174|Actinobacteria,4EXHA@85013|Frankiales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TLS3_k127_1309725_5	1120948.KB903222_gene579	3.311e-10	63.0	COG0031@1|root,COG0031@2|Bacteria,2GK6J@201174|Actinobacteria,4DXJE@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.140	ko:K21949	-	-	R11705	-	ko00000,ko01000	-	-	-	PALP
TLS3_k127_1309898_12	1120948.KB903222_gene579	9.256e-10	63.0	COG0031@1|root,COG0031@2|Bacteria,2GK6J@201174|Actinobacteria,4DXJE@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.140	ko:K21949	-	-	R11705	-	ko00000,ko01000	-	-	-	PALP
TLS3_k127_1309898_13	67352.JODS01000030_gene1037	0.0008709	49.0	2EGCD@1|root,33A46@2|Bacteria,2GIVH@201174|Actinobacteria	201174|Actinobacteria	S	Septum formation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190,Septum_form
TLS3_k127_1309898_10	1206731.BAGB01000040_gene8120	3.817e-16	92.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4FURI@85025|Nocardiaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
TLS3_k127_1309898_2	479432.Sros_4323	4.984e-108	367.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria,4EIHJ@85012|Streptosporangiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
TLS3_k127_1309898_11	1463825.JNXC01000026_gene3093	1.41e-10	71.0	2AXY9@1|root,31PZK@2|Bacteria,2HS6N@201174|Actinobacteria,4ECMM@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1309898_1	469383.Cwoe_1926	6.608e-209	662.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4CRYD@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
TLS3_k127_1309898_8	285535.JOEY01000078_gene5861	9.522e-43	158.0	COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
TLS3_k127_1309898_9	1120948.KB903240_gene4140	5.106e-37	157.0	COG3832@1|root,COG3832@2|Bacteria,2H75S@201174|Actinobacteria,4E225@85010|Pseudonocardiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_1309898_7	1123023.JIAI01000021_gene2421	4.988e-74	259.0	COG1357@1|root,COG1357@2|Bacteria,2I8N2@201174|Actinobacteria,4E7RX@85010|Pseudonocardiales	201174|Actinobacteria	S	Pentapeptide repeats (9 copies)	mfpA	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
TLS3_k127_1309898_6	1121033.AUCF01000004_gene5068	8.624e-75	264.0	COG0223@1|root,COG0223@2|Bacteria,1N59R@1224|Proteobacteria,2UIHM@28211|Alphaproteobacteria,2JYNE@204441|Rhodospirillales	204441|Rhodospirillales	J	Formyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_N
TLS3_k127_1309898_4	1068980.ARVW01000001_gene8054	2.988e-90	307.0	COG1073@1|root,COG1073@2|Bacteria,2I9HJ@201174|Actinobacteria,4E2AV@85010|Pseudonocardiales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
TLS3_k127_1309898_3	1120948.KB903240_gene4141	2.107e-92	313.0	COG1028@1|root,COG1028@2|Bacteria,2I3QQ@201174|Actinobacteria,4E8HQ@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_1309898_0	1120948.KB903240_gene4143	0.0	1035.0	COG3848@1|root,COG3848@2|Bacteria,2I3FP@201174|Actinobacteria,4E9TT@85010|Pseudonocardiales	201174|Actinobacteria	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
TLS3_k127_1309898_5	1120948.KB903240_gene4144	3.966e-75	280.0	COG0574@1|root,COG0574@2|Bacteria,2HEK7@201174|Actinobacteria,4E852@85010|Pseudonocardiales	201174|Actinobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N
TLS3_k127_132420_5	1120705.FG95_03259	2.977e-18	98.0	2AEJW@1|root,314FG@2|Bacteria,1NBZ3@1224|Proteobacteria,2UZJ6@28211|Alphaproteobacteria,2K8ZV@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_132420_2	1120948.KB903217_gene1396	8.198e-74	250.0	COG1764@1|root,COG1764@2|Bacteria,2IFFB@201174|Actinobacteria,4E3HZ@85010|Pseudonocardiales	201174|Actinobacteria	O	PFAM OsmC-like protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
TLS3_k127_132420_3	749927.AMED_2947	3.68e-53	191.0	COG1846@1|root,COG1846@2|Bacteria,2IMA9@201174|Actinobacteria,4E4H2@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
TLS3_k127_132420_4	1120948.KB903240_gene4030	8.708e-34	132.0	COG2261@1|root,COG2261@2|Bacteria,2GQR5@201174|Actinobacteria,4E75F@85010|Pseudonocardiales	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
TLS3_k127_132420_1	1120948.KB903217_gene1400	3.926e-120	394.0	COG4759@1|root,COG4759@2|Bacteria,2GRSQ@201174|Actinobacteria,4DYIC@85010|Pseudonocardiales	201174|Actinobacteria	O	Sucrase/ferredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Suc_Fer-like
TLS3_k127_132420_0	1120948.KB903217_gene1401	6.702e-173	552.0	COG2850@1|root,COG2850@2|Bacteria,2GMR2@201174|Actinobacteria,4DYRP@85010|Pseudonocardiales	201174|Actinobacteria	S	Cupin superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_4
TLS3_k127_1334614_0	1120948.KB903245_gene3643	3.686e-199	626.0	COG2185@1|root,COG2185@2|Bacteria,2I2N3@201174|Actinobacteria,4DZXB@85010|Pseudonocardiales	201174|Actinobacteria	I	Methylmalonyl-CoA mutase	meaA	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
TLS3_k127_1334614_3	1122611.KB904007_gene7768	7.04e-44	164.0	COG2329@1|root,COG2329@2|Bacteria,2IQBH@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
TLS3_k127_1334614_4	66373.JOFQ01000003_gene5833	6.182e-37	144.0	COG2050@1|root,COG2050@2|Bacteria,2IQXX@201174|Actinobacteria	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
TLS3_k127_1334614_1	1120948.KB903245_gene3641	5.904e-119	391.0	COG0840@1|root,COG0840@2|Bacteria,2IN5K@201174|Actinobacteria,4E4P0@85010|Pseudonocardiales	201174|Actinobacteria	NT	transmembrane signaling receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1334614_2	1120948.KB903245_gene3640	1.683e-77	263.0	COG0494@1|root,COG0494@2|Bacteria,2IG9K@201174|Actinobacteria,4E3AD@85010|Pseudonocardiales	201174|Actinobacteria	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_1334614_5	1120948.KB903245_gene3639	1.509e-16	80.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria,4DYQB@85010|Pseudonocardiales	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
TLS3_k127_1348638_4	1120948.KB903228_gene4811	4.583e-71	247.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4DXCK@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_1348638_3	1120948.KB903228_gene4810	4.674e-82	289.0	COG0279@1|root,COG0279@2|Bacteria,2IIGW@201174|Actinobacteria,4E3PZ@85010|Pseudonocardiales	201174|Actinobacteria	G	SIS domain	gmhA	-	2.7.7.71,5.3.1.28	ko:K03271,ko:K15669	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769,R09772	RC00002,RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
TLS3_k127_1348638_0	1120948.KB903228_gene4809	1.086e-145	486.0	COG0615@1|root,COG2870@1|root,COG4221@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,COG4221@2|Bacteria,2GKU1@201174|Actinobacteria,4DYQE@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB,SIS_2
TLS3_k127_1348638_1	1120948.KB903228_gene4809	2.571e-106	364.0	COG0615@1|root,COG2870@1|root,COG4221@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,COG4221@2|Bacteria,2GKU1@201174|Actinobacteria,4DYQE@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB,SIS_2
TLS3_k127_1348638_5	1229203.KI301992_gene1724	9.293e-08	63.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
TLS3_k127_1348638_2	1120948.KB903228_gene4807	5.918e-83	290.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,2GKU1@201174|Actinobacteria,4DYQE@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,PfkB
TLS3_k127_1360031_0	2074.JNYD01000022_gene1437	2.262e-190	616.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DXJW@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
TLS3_k127_1360031_4	1206101.AZXC01000019_gene1432	1.462e-57	210.0	COG2120@1|root,COG2120@2|Bacteria,2IDT2@201174|Actinobacteria	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
TLS3_k127_1360031_6	1532557.JL37_16855	9.593e-30	136.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2VPR2@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_1360031_2	1123024.AUII01000031_gene527	5.563e-121	416.0	COG0500@1|root,COG2226@2|Bacteria,2I3SA@201174|Actinobacteria,4EF8K@85010|Pseudonocardiales	201174|Actinobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
TLS3_k127_1360031_3	1380390.JIAT01000009_gene1598	3.409e-93	339.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria,4CTX9@84995|Rubrobacteria	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_19
TLS3_k127_1360031_1	1380356.JNIK01000004_gene91	4.109e-163	526.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
TLS3_k127_1360031_5	2074.JNYD01000007_gene1987	6.783e-46	176.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,Trans_reg_C
TLS3_k127_1378260_4	1120948.KB903244_gene3002	2.162e-22	107.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4E13K@85010|Pseudonocardiales	201174|Actinobacteria	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
TLS3_k127_1378260_0	2074.JNYD01000011_gene164	9.837e-112	381.0	COG1752@1|root,COG1752@2|Bacteria,2IDUX@201174|Actinobacteria	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
TLS3_k127_1378260_3	1123024.AUII01000036_gene3143	1.94e-27	123.0	2F6DN@1|root,33YWV@2|Bacteria,2GVAE@201174|Actinobacteria,4ECVM@85010|Pseudonocardiales	201174|Actinobacteria	S	Sap, sulfolipid-1-addressing protein	-	-	-	-	-	-	-	-	-	-	-	-	SfLAP
TLS3_k127_1378260_1	1120949.KB903294_gene4043	3.298e-70	252.0	COG2197@1|root,COG2197@2|Bacteria,2GN80@201174|Actinobacteria,4D9BA@85008|Micromonosporales	201174|Actinobacteria	KT	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_1378260_2	66897.DJ64_30215	4.65e-31	128.0	COG4585@1|root,COG4585@2|Bacteria,2GNBG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
TLS3_k127_1423024_3	1120948.KB903246_gene3279	5.375e-93	330.0	COG2887@1|root,COG2887@2|Bacteria,2I94N@201174|Actinobacteria,4DZ71@85010|Pseudonocardiales	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
TLS3_k127_1423024_2	675635.Psed_1065	1.429e-94	336.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4DZFN@85010|Pseudonocardiales	201174|Actinobacteria	S	metal-dependent phosphoesterase, PHP family	PPA1328	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
TLS3_k127_1423024_4	1120948.KB903246_gene3281	1.018e-76	260.0	COG3428@1|root,COG3428@2|Bacteria,2IA1C@201174|Actinobacteria,4E0GI@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Bacterial membrane flanked domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
TLS3_k127_1423024_6	65497.JODV01000001_gene3724	3.15e-05	50.0	28XBP@1|root,2ZJ9J@2|Bacteria,2GXT0@201174|Actinobacteria,4E7DD@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1423024_5	405948.SACE_1052	3.434e-37	145.0	COG1051@1|root,COG1051@2|Bacteria,2IQEU@201174|Actinobacteria,4E5VV@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_1423024_1	1120948.KB903246_gene3282	1.092e-95	318.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,4DZ99@85010|Pseudonocardiales	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
TLS3_k127_1423024_0	1120948.KB903246_gene3283	2.336e-100	331.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4DYQC@85010|Pseudonocardiales	201174|Actinobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
TLS3_k127_1428564_0	1120948.KB903248_gene4279	1.193e-170	547.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4DYWZ@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2158c	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_1428564_1	1120948.KB903248_gene4281	1.904e-72	246.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4DYPX@85010|Pseudonocardiales	201174|Actinobacteria	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
TLS3_k127_1430554_10	1386089.N865_11160	4.347e-42	164.0	2A2HJ@1|root,30QV0@2|Bacteria,2IN3M@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1430554_5	1120948.KB903218_gene2195	7.997e-208	649.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DZDK@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_1430554_3	479435.Kfla_2031	8.3e-271	863.0	COG2909@1|root,COG2909@2|Bacteria,2I999@201174|Actinobacteria,4DU9W@85009|Propionibacteriales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_1430554_13	479435.Kfla_2032	1.139e-26	113.0	2FFAT@1|root,3478H@2|Bacteria,2GSGG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1430554_8	1120948.KB903218_gene2197	7.736e-60	214.0	COG4097@1|root,COG4097@2|Bacteria,2GQH2@201174|Actinobacteria,4E52U@85010|Pseudonocardiales	201174|Actinobacteria	P	Ferric reductase like transmembrane component	-	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
TLS3_k127_1430554_2	1120948.KB903244_gene2843	1.098e-294	915.0	COG1651@1|root,COG3004@1|root,COG1651@2|Bacteria,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria,4E12A@85010|Pseudonocardiales	201174|Actinobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_1,Thioredoxin_4
TLS3_k127_1430554_1	1120948.KB903218_gene2198	0.0	1207.0	COG3280@1|root,COG3280@2|Bacteria,2GJTB@201174|Actinobacteria,4E23P@85010|Pseudonocardiales	201174|Actinobacteria	G	Alpha amylase, catalytic domain	treY	GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
TLS3_k127_1430554_0	1120948.KB903218_gene2199	0.0	1355.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4DZ6I@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
TLS3_k127_1430554_7	1120948.KB903218_gene2200	4.427e-68	237.0	COG0537@1|root,COG0537@2|Bacteria,2IKWU@201174|Actinobacteria	201174|Actinobacteria	FG	Histidine triad (Hit) protein	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
TLS3_k127_1430554_9	1120948.KB903218_gene2201	1.637e-50	186.0	COG0406@1|root,COG0406@2|Bacteria,2GM22@201174|Actinobacteria,4E6PX@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
TLS3_k127_1430554_12	561175.KB894095_gene2273	9.636e-36	144.0	COG3548@1|root,COG3548@2|Bacteria,2IQG2@201174|Actinobacteria,4EQPI@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
TLS3_k127_1430554_6	479431.Namu_4871	2.136e-188	606.0	COG0477@1|root,COG2223@1|root,COG2223@2|Bacteria,COG2814@2|Bacteria,2H4H5@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_1430554_4	675635.Psed_1453	1.047e-209	664.0	COG0154@1|root,COG0154@2|Bacteria,2GUUU@201174|Actinobacteria,4DZ8T@85010|Pseudonocardiales	201174|Actinobacteria	J	Amidase	amdA	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
TLS3_k127_1430554_11	1120948.KB903218_gene2072	3.574e-36	153.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4E32T@85010|Pseudonocardiales	201174|Actinobacteria	L	HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH
TLS3_k127_1441532_0	1123024.AUII01000026_gene2543	1.967e-210	666.0	COG0845@1|root,COG4770@1|root,COG4799@1|root,COG0845@2|Bacteria,COG4770@2|Bacteria,COG4799@2|Bacteria,2GIZP@201174|Actinobacteria,4DZJ9@85010|Pseudonocardiales	201174|Actinobacteria	I	Acetyl propionyl-CoA carboxylase, alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	ACC_central,Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
TLS3_k127_1441615_0	1120948.KB903217_gene1584	1.322e-248	779.0	COG1674@1|root,COG1674@2|Bacteria,2GJBR@201174|Actinobacteria,4DZA2@85010|Pseudonocardiales	201174|Actinobacteria	D	PFAM FtsK SpoIIIE family	eccCa	GO:0002790,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0020012,GO:0030312,GO:0030682,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0040007,GO:0042783,GO:0042886,GO:0043207,GO:0044110,GO:0044116,GO:0044117,GO:0044315,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0075136	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE
TLS3_k127_1441615_2	1120948.KB903217_gene1583	2.017e-95	332.0	28MNM@1|root,2ZAY5@2|Bacteria,2GNDI@201174|Actinobacteria,4DXH3@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM secretion protein snm4	eccD4	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	YukD
TLS3_k127_1441615_3	1120948.KB903217_gene1582	1.3e-86	325.0	COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria,4E0EP@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the peptidase S8 family	mycP4	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009405,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0031224,GO:0031226,GO:0032879,GO:0040007,GO:0043170,GO:0044238,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0051046,GO:0051049,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	-	ko:K14743	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
TLS3_k127_1441615_4	208444.JNYY01000005_gene6513	4.427e-75	286.0	2E75V@1|root,331Q0@2|Bacteria,2GMQH@201174|Actinobacteria,4DXZD@85010|Pseudonocardiales	201174|Actinobacteria	S	Type VII secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	EccE
TLS3_k127_1441615_5	1120948.KB903217_gene1580	9.08e-60	231.0	2EBWS@1|root,335W2@2|Bacteria,2GK3K@201174|Actinobacteria,4DYRS@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1441615_7	1206744.BAGL01000128_gene6879	2.017e-20	96.0	COG2146@1|root,COG2146@2|Bacteria,2HRRY@201174|Actinobacteria,4G7WY@85025|Nocardiaceae	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
TLS3_k127_1441615_6	2074.JNYD01000002_gene5739	3.655e-54	192.0	COG0346@1|root,COG0346@2|Bacteria,2IKRF@201174|Actinobacteria,4E4DZ@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_1441615_1	1120948.KB903217_gene1579	2.547e-124	403.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4DZVD@85010|Pseudonocardiales	201174|Actinobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
TLS3_k127_1477421_0	644283.Micau_0577	8.102e-291	911.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4D8QQ@85008|Micromonosporales	201174|Actinobacteria	P	Copper-translocating P-type atpase	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
TLS3_k127_1477421_1	1120948.KB903218_gene2226	6.57e-108	360.0	COG0520@1|root,COG0520@2|Bacteria,2GJA4@201174|Actinobacteria,4E0HN@85010|Pseudonocardiales	201174|Actinobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
TLS3_k127_1519987_5	1120948.KB903245_gene3496	5.246e-13	72.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4DY3D@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator with HTH domain and aminotransferase domain	pdxR	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
TLS3_k127_1519987_1	1120948.KB903223_gene176	2.823e-125	411.0	COG3483@1|root,COG3483@2|Bacteria,2GNB1@201174|Actinobacteria,4E0DW@85010|Pseudonocardiales	201174|Actinobacteria	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
TLS3_k127_1519987_0	1120948.KB903245_gene3495	2.384e-148	482.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4DX8H@85010|Pseudonocardiales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
TLS3_k127_1519987_3	1120948.KB903245_gene3494	3.537e-65	227.0	2ECK0@1|root,336I4@2|Bacteria,2IGST@201174|Actinobacteria,4E6C1@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3515)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3515
TLS3_k127_1519987_4	882082.SaccyDRAFT_1065	2.077e-25	111.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria,4E5C4@85010|Pseudonocardiales	201174|Actinobacteria	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
TLS3_k127_1519987_2	1120948.KB903245_gene3492	1.581e-114	377.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,4DY1U@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0008150,GO:0040007	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2977c	AIRS,AIRS_C
TLS3_k127_1524324_3	1120948.KB903240_gene3941	5.777e-29	118.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,4E3S8@85010|Pseudonocardiales	201174|Actinobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0008150,GO:0040007	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
TLS3_k127_1524324_1	1120948.KB903240_gene3942	1.161e-104	361.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4DYGN@85010|Pseudonocardiales	201174|Actinobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
TLS3_k127_1524324_0	1120948.KB903240_gene3943	7.567e-142	470.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4DYZ4@85010|Pseudonocardiales	201174|Actinobacteria	E	Creatinase Prolidase N-terminal domain	pepQ	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
TLS3_k127_1524580_1	1120948.KB903240_gene4132	1.651e-97	341.0	COG1024@1|root,COG1024@2|Bacteria,2HHR6@201174|Actinobacteria,4DXU9@85010|Pseudonocardiales	201174|Actinobacteria	I	enoyl-CoA hydratase	Echdc	-	-	-	-	-	-	-	-	-	-	-	ECH_1
TLS3_k127_1524580_4	1120948.KB903240_gene4133	4.916e-67	238.0	2CAWP@1|root,32T0S@2|Bacteria,2IFTJ@201174|Actinobacteria,4E4KJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4383
TLS3_k127_1524580_9	1120948.KB903220_gene136	8.894e-18	88.0	292W1@1|root,2ZQDH@2|Bacteria,2H06B@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1524580_2	1120948.KB903218_gene2049	1.822e-74	259.0	COG0406@1|root,COG0406@2|Bacteria,2H5ER@201174|Actinobacteria,4EB6I@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
TLS3_k127_1524580_0	1120948.KB903243_gene2308	9.825e-183	583.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4DYM9@85010|Pseudonocardiales	201174|Actinobacteria	C	Alpha-hydroxyacid dehydrogenase, FMN-dependent L-lactate dehydrogenase	-	-	1.1.2.3,1.13.12.4	ko:K00101,ko:K00467	ko00620,ko01100,map00620,map01100	-	R00196,R00319	RC00044,RC01312	ko00000,ko00001,ko01000	-	-	-	FMN_dh
TLS3_k127_1524580_5	298653.Franean1_3128	4.81e-62	219.0	COG3631@1|root,COG3631@2|Bacteria,2IGEH@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
TLS3_k127_1524580_6	298655.KI912267_gene7931	3.234e-59	219.0	COG1506@1|root,COG1506@2|Bacteria,2I3Z4@201174|Actinobacteria,4ESXP@85013|Frankiales	201174|Actinobacteria	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
TLS3_k127_1524580_7	330084.JNYZ01000020_gene4608	4.121e-43	164.0	COG0251@1|root,COG0251@2|Bacteria,2IHNE@201174|Actinobacteria,4E2XD@85010|Pseudonocardiales	201174|Actinobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
TLS3_k127_1524580_3	1123024.AUII01000001_gene3112	4.561e-71	250.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	yigB	-	3.1.3.10,3.1.3.102,3.1.3.104	ko:K07025,ko:K20862,ko:K20866	ko00010,ko00740,ko01100,ko01110,ko01120,map00010,map00740,map01100,map01110,map01120	M00125	R00548,R00947,R07280	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2,Hydrolase
TLS3_k127_1524580_8	1123023.JIAI01000006_gene319	4.582e-18	85.0	COG3848@1|root,COG3848@2|Bacteria,2I3FP@201174|Actinobacteria,4EAD5@85010|Pseudonocardiales	201174|Actinobacteria	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
TLS3_k127_1536137_2	1120948.KB903220_gene125	4.721e-81	277.0	COG0419@1|root,COG0419@2|Bacteria,2HU66@201174|Actinobacteria	201174|Actinobacteria	L	DNA repair	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_23,AAA_27
TLS3_k127_1536137_1	1120948.KB903220_gene126	2.217e-138	451.0	COG0420@1|root,COG0420@2|Bacteria	2|Bacteria	L	3'-5' exonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
TLS3_k127_1536137_0	1120948.KB903220_gene129	7.21e-238	746.0	COG3540@1|root,COG3540@2|Bacteria,2GNZ5@201174|Actinobacteria,4DXI0@85010|Pseudonocardiales	201174|Actinobacteria	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
TLS3_k127_1536137_3	1123024.AUII01000006_gene4709	4.135e-77	269.0	2CAME@1|root,33Y8E@2|Bacteria,2HZMK@201174|Actinobacteria,4E3U4@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1536137_6	66373.JOFQ01000003_gene5800	3.837e-05	49.0	COG2203@1|root,COG2203@2|Bacteria,2IG5I@201174|Actinobacteria	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
TLS3_k127_1536137_4	1150864.MILUP08_40444	4.259e-34	136.0	COG0346@1|root,COG0346@2|Bacteria,2IQ7F@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS3_k127_1536137_5	1120948.KB903244_gene3155	1.899e-14	75.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
TLS3_k127_1547602_0	1120948.KB903229_gene5107	2.618e-236	735.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4DZY3@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA2	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
TLS3_k127_1562434_10	2074.JNYD01000035_gene6699	1.617e-15	90.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria,4DYQ1@85010|Pseudonocardiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
TLS3_k127_1562434_1	2074.JNYD01000035_gene6698	2.526e-108	361.0	COG1840@1|root,COG1840@2|Bacteria,2I0VD@201174|Actinobacteria,4E2FQ@85010|Pseudonocardiales	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
TLS3_k127_1562434_5	1120948.KB903245_gene3464	1.447e-75	273.0	COG5637@1|root,COG5637@2|Bacteria,2GP5P@201174|Actinobacteria,4E5SQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
TLS3_k127_1562434_12	1120948.KB903229_gene5100	7.797e-14	73.0	COG1842@1|root,COG1842@2|Bacteria,2GRMV@201174|Actinobacteria,4E7HG@85010|Pseudonocardiales	201174|Actinobacteria	KT	Phage shock protein A	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1562434_11	1157640.AQWO01000002_gene4380	6.827e-14	82.0	COG2197@1|root,COG2197@2|Bacteria,2I91X@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
TLS3_k127_1562434_8	1120948.KB903217_gene1047	3.371e-52	199.0	2E3SC@1|root,32YPX@2|Bacteria,2HPCF@201174|Actinobacteria,4E4BJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
TLS3_k127_1562434_0	1120948.KB903245_gene3466	1.416e-124	409.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,4DXDQ@85010|Pseudonocardiales	201174|Actinobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
TLS3_k127_1562434_2	1120948.KB903245_gene3467	1.032e-106	351.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4DZ7R@85010|Pseudonocardiales	201174|Actinobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
TLS3_k127_1562434_9	1120948.KB903245_gene3468	6.361e-29	115.0	COG0333@1|root,COG0333@2|Bacteria,2GQP3@201174|Actinobacteria,4E6MS@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
TLS3_k127_1562434_4	1120948.KB903245_gene3469	1.409e-85	287.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,4E2ZT@85010|Pseudonocardiales	201174|Actinobacteria	S	metal-binding protein	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
TLS3_k127_1562434_3	1120948.KB903245_gene3470	6.917e-91	316.0	COG3599@1|root,COG3599@2|Bacteria,2I2NA@201174|Actinobacteria,4DZXD@85010|Pseudonocardiales	201174|Actinobacteria	D	Cell division initiation protein	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1562434_7	1120948.KB903245_gene3471	7.915e-64	222.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4E33S@85010|Pseudonocardiales	201174|Actinobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
TLS3_k127_1562434_6	1120948.KB903245_gene3472	4.839e-73	250.0	COG1670@1|root,COG1670@2|Bacteria,2IQW2@201174|Actinobacteria,4E2W3@85010|Pseudonocardiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TLS3_k127_1590646_1	1120948.KB903228_gene4802	1.904e-77	267.0	COG3569@1|root,COG3569@2|Bacteria,2GJTH@201174|Actinobacteria,4E1SD@85010|Pseudonocardiales	201174|Actinobacteria	G	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
TLS3_k127_1590646_0	1120948.KB903228_gene4803	4.132e-200	637.0	COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,4DZSW@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,DUF3553,Helicase_C,RecQ_Zn_bind
TLS3_k127_1591732_2	1120948.KB903217_gene1170	7.62e-69	240.0	2ES16@1|root,33JK8@2|Bacteria,2INDR@201174|Actinobacteria,4E4D2@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1591732_0	1120948.KB903217_gene1171	1.006e-151	487.0	COG0791@1|root,COG0791@2|Bacteria,2I38D@201174|Actinobacteria,4DZC6@85010|Pseudonocardiales	201174|Actinobacteria	M	Cell wall-associated hydrolase, invasion-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
TLS3_k127_1591732_3	66429.JOFL01000001_gene4679	3.388e-47	174.0	COG0346@1|root,COG0346@2|Bacteria,2II3E@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_1591732_1	1120948.KB903226_gene5480	4.939e-87	297.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4DYE7@85010|Pseudonocardiales	201174|Actinobacteria	S	NAD- dependent epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
TLS3_k127_1591732_4	570268.ANBB01000077_gene3671	4.841e-09	61.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4EFTK@85012|Streptosporangiales	201174|Actinobacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
TLS3_k127_1592411_0	1120948.KB903248_gene4299	3.195e-271	849.0	COG3200@1|root,COG3200@2|Bacteria,2GJBX@201174|Actinobacteria,4DZSR@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the class-II DAHP synthase family	aroG	GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016043,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0022607,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2178c	DAHP_synth_2
TLS3_k127_1592411_2	1120948.KB903248_gene4302	1.456e-83	282.0	2CPKU@1|root,32SJD@2|Bacteria,2I3ZF@201174|Actinobacteria,4E2ZV@85010|Pseudonocardiales	201174|Actinobacteria	G	Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA	-	GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040007,GO:0042802	-	-	-	-	-	-	-	-	-	-	DUF5051
TLS3_k127_1592411_1	1120948.KB903248_gene4303	8.154e-120	391.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4DZCI@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TLS3_k127_1592411_3	1120948.KB903248_gene4304	2.454e-32	141.0	COG1647@1|root,COG1647@2|Bacteria,2GM1Y@201174|Actinobacteria,4DZX1@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM alpha beta hydrolase fold	yvaK	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
TLS3_k127_1600379_0	1445613.JALM01000036_gene2873	0.0	1249.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4E1F5@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the GcvT family	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
TLS3_k127_1600379_1	1445613.JALM01000036_gene2871	5.155e-96	325.0	COG0685@1|root,COG0685@2|Bacteria,2I92A@201174|Actinobacteria,4E35Z@85010|Pseudonocardiales	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
TLS3_k127_1600379_2	1123023.JIAI01000001_gene6373	2.439e-07	53.0	COG0404@1|root,COG0404@2|Bacteria,2I8C4@201174|Actinobacteria,4E0XR@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the GcvT family	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1989,GCV_T,GCV_T_C
TLS3_k127_1653871_4	1123024.AUII01000019_gene3990	5.509e-60	224.0	COG2898@1|root,COG2898@2|Bacteria,2GM2C@201174|Actinobacteria,4E8X8@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	lysX	-	-	-	-	-	-	-	-	-	-	-	DUF2156
TLS3_k127_1653871_1	1120948.KB903240_gene4003	4.256e-127	414.0	COG3965@1|root,COG3965@2|Bacteria,2HRDF@201174|Actinobacteria,4EAJ2@85010|Pseudonocardiales	201174|Actinobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
TLS3_k127_1653871_7	1120948.KB903240_gene4004	1.092e-39	166.0	2AK9F@1|root,31AZU@2|Bacteria,2II09@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1653871_5	1120948.KB903218_gene2205	2.205e-49	179.0	COG3224@1|root,COG3224@2|Bacteria,2GQKQ@201174|Actinobacteria,4E6P1@85010|Pseudonocardiales	201174|Actinobacteria	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD
TLS3_k127_1653871_0	1120948.KB903218_gene2206	5.2e-209	668.0	COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4E0D7@85010|Pseudonocardiales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,zf-UBP
TLS3_k127_1653871_6	247156.NFA_33160	7.672e-46	170.0	COG5470@1|root,COG5470@2|Bacteria,2IM3I@201174|Actinobacteria,4G1GF@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
TLS3_k127_1653871_2	1120948.KB903218_gene2207	2.718e-89	298.0	COG0500@1|root,COG2226@2|Bacteria,2I3AK@201174|Actinobacteria,4E2PW@85010|Pseudonocardiales	201174|Actinobacteria	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_1653871_3	1120948.KB903218_gene2209	1.276e-87	308.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4DXTB@85010|Pseudonocardiales	201174|Actinobacteria	P	cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
TLS3_k127_167736_1	1120948.KB903245_gene3441	1.672e-97	333.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,4DZYS@85010|Pseudonocardiales	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
TLS3_k127_167736_0	1120948.KB903245_gene3442	2.316e-113	374.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4DXZX@85010|Pseudonocardiales	201174|Actinobacteria	U	Belongs to the peptidase S26 family	lepB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
TLS3_k127_167792_0	2074.JNYD01000004_gene5061	1.329e-103	341.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZWD@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_167792_1	570268.ANBB01000062_gene846	9.841e-58	207.0	COG0500@1|root,COG2226@2|Bacteria,2GP9N@201174|Actinobacteria,4EIJZ@85012|Streptosporangiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
TLS3_k127_167792_2	710696.Intca_3465	3.183e-20	93.0	COG1280@1|root,COG1280@2|Bacteria,2GMDP@201174|Actinobacteria,4FEGN@85021|Intrasporangiaceae	201174|Actinobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
TLS3_k127_1679228_1	66875.JODY01000006_gene2255	4.97e-70	243.0	COG0028@1|root,COG0028@2|Bacteria,2GN3X@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	mdlC	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TLS3_k127_1679228_0	1120948.KB903240_gene3900	4.281e-194	618.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4DYNG@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
TLS3_k127_1705731_3	1120948.KB903219_gene795	7.792e-32	129.0	COG0746@1|root,COG0746@2|Bacteria,2IACX@201174|Actinobacteria	201174|Actinobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
TLS3_k127_1705731_1	1120948.KB903219_gene792	6.186e-70	239.0	COG0748@1|root,COG0748@2|Bacteria,2I2RZ@201174|Actinobacteria,4EFAD@85010|Pseudonocardiales	201174|Actinobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
TLS3_k127_1705731_2	1137271.AZUM01000001_gene1039	1.958e-50	190.0	COG3542@1|root,COG3542@2|Bacteria,2IFG5@201174|Actinobacteria,4E5NZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5,DUF952
TLS3_k127_1705731_0	1120948.KB903219_gene790	3.335e-315	988.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4E8SY@85010|Pseudonocardiales	201174|Actinobacteria	M	Transglycosylase	pbp1A	GO:0001666,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0008144,GO:0008150,GO:0008658,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0033218,GO:0033293,GO:0033554,GO:0036094,GO:0036293,GO:0036294,GO:0042221,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0050896,GO:0051716,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0097159,GO:1901363,GO:1901681	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
TLS3_k127_1708891_3	1120948.KB903240_gene3976	5.262e-57	212.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4E01I@85010|Pseudonocardiales	201174|Actinobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
TLS3_k127_1708891_0	1120948.KB903240_gene3977	8.005e-239	745.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,4DZ8F@85010|Pseudonocardiales	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PALP
TLS3_k127_1708891_2	1120948.KB903240_gene3978	2.593e-137	446.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4DY2J@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the TrpC family	trpC	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
TLS3_k127_1708891_4	1120948.KB903240_gene3979	1.109e-41	176.0	2DSKP@1|root,33GIP@2|Bacteria,2HNGY@201174|Actinobacteria,4E6N5@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Tryptophan-associated transmembrane protein (Trp_oprn_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Trp_oprn_chp
TLS3_k127_1708891_1	675635.Psed_2862	1.414e-218	688.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4DYDE@85010|Pseudonocardiales	201174|Actinobacteria	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
TLS3_k127_1711414_2	1120948.KB903247_gene4478	6.175e-32	141.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4DXRM@85010|Pseudonocardiales	201174|Actinobacteria	J	ribonuclease, Rne Rng family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
TLS3_k127_1711414_0	1120948.KB903247_gene4477	2.201e-97	333.0	COG5011@1|root,COG5011@2|Bacteria,2GIS7@201174|Actinobacteria,4E06B@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
TLS3_k127_1711414_1	1123024.AUII01000008_gene1808	1.996e-34	136.0	COG1247@1|root,COG1247@2|Bacteria,2IM56@201174|Actinobacteria,4E62E@85010|Pseudonocardiales	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
TLS3_k127_1721680_5	1179773.BN6_03570	2.003e-07	59.0	2F5G1@1|root,33Y1Q@2|Bacteria,2HVSF@201174|Actinobacteria,4E37E@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1721680_3	1120948.KB903229_gene5371	4.096e-47	177.0	2DRQG@1|root,33CMQ@2|Bacteria,2IFEG@201174|Actinobacteria,4E5NC@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3180)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3180
TLS3_k127_1721680_1	2074.JNYD01000009_gene5205	1.024e-52	202.0	COG0801@1|root,COG0801@2|Bacteria,2H3G6@201174|Actinobacteria,4E3MQ@85010|Pseudonocardiales	201174|Actinobacteria	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
TLS3_k127_1721680_2	1120948.KB903229_gene5369	2.336e-47	175.0	COG1539@1|root,COG1539@2|Bacteria,2IHSW@201174|Actinobacteria,4E4Z9@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0008150,GO:0040007	1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8	ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840	R03503,R03504,R11037,R11073	RC00002,RC00017,RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
TLS3_k127_1721680_0	1120948.KB903229_gene5368	1.115e-139	448.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4DYEE@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
TLS3_k127_1721680_4	1120948.KB903229_gene5367	5.527e-18	87.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,4DXVF@85010|Pseudonocardiales	201174|Actinobacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
TLS3_k127_1750588_3	446462.Amir_4256	1.453e-15	83.0	COG1181@1|root,COG1181@2|Bacteria,2I8SB@201174|Actinobacteria,4EA5X@85010|Pseudonocardiales	201174|Actinobacteria	M	D-ala D-ala ligase C-terminus	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
TLS3_k127_1750588_0	1306174.JODP01000008_gene2685	2.242e-173	567.0	COG2232@1|root,COG2232@2|Bacteria,2I752@201174|Actinobacteria	201174|Actinobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1750588_1	1306174.JODP01000008_gene2686	5.835e-109	358.0	COG2175@1|root,COG2175@2|Bacteria,2GNUC@201174|Actinobacteria	201174|Actinobacteria	Q	taurine catabolism dioxygenase	-	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
TLS3_k127_1750588_2	929712.KI912613_gene4159	1.426e-52	188.0	COG4122@1|root,COG4122@2|Bacteria,2GP7A@201174|Actinobacteria,4CQMJ@84995|Rubrobacteria	84995|Rubrobacteria	S	O-methyltransferase family 3	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
TLS3_k127_1754882_6	1120948.KB903217_gene1595	7.585e-36	138.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4DZZX@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006082,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008784,GO:0009058,GO:0009059,GO:0009078,GO:0009079,GO:0009252,GO:0009273,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0019842,GO:0030170,GO:0030203,GO:0030632,GO:0034645,GO:0036094,GO:0036361,GO:0040007,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,TsaE
TLS3_k127_1754882_1	1120948.KB903217_gene1596	5.575e-181	576.0	COG2267@1|root,COG2267@2|Bacteria,2GMCK@201174|Actinobacteria,4DXN6@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
TLS3_k127_1754882_5	685727.REQ_35300	1.952e-42	167.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4G0QI@85025|Nocardiaceae	201174|Actinobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	tsaE	GO:0008150,GO:0040007	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
TLS3_k127_1754882_2	675635.Psed_5365	9.369e-60	214.0	COG1214@1|root,COG1214@2|Bacteria,2GMTM@201174|Actinobacteria,4E1VB@85010|Pseudonocardiales	201174|Actinobacteria	O	Glycoprotease family	yeaZ	GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
TLS3_k127_1754882_3	1120948.KB903217_gene1597	2.39e-54	196.0	COG0454@1|root,COG0456@2|Bacteria,2IM9R@201174|Actinobacteria,4E42K@85010|Pseudonocardiales	201174|Actinobacteria	K	Ribosomal-protein-alanine acetyltransferase	rimI	GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
TLS3_k127_1754882_4	1120948.KB903217_gene1598	7.938e-49	186.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4E4IF@85010|Pseudonocardiales	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
TLS3_k127_1754882_0	1120948.KB903217_gene1599	6.539e-292	912.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4DYFQ@85010|Pseudonocardiales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009295,GO:0009408,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016465,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042026,GO:0042262,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043388,GO:0043590,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051716,GO:0061077,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090143,GO:0090304,GO:0097159,GO:0101031,GO:1901360,GO:1901363,GO:1990220,GO:2000677,GO:2000679	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
TLS3_k127_1758108_0	1120948.KB903246_gene3263	5.449e-214	675.0	COG0726@1|root,COG1215@1|root,COG1835@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,COG1835@2|Bacteria,2GJCE@201174|Actinobacteria,4DZV9@85010|Pseudonocardiales	201174|Actinobacteria	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3,Glyco_tranf_2_3,Polysacc_deac_1
TLS3_k127_1758108_1	1120948.KB903246_gene3263	3.892e-116	383.0	COG0726@1|root,COG1215@1|root,COG1835@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,COG1835@2|Bacteria,2GJCE@201174|Actinobacteria,4DZV9@85010|Pseudonocardiales	201174|Actinobacteria	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3,Glyco_tranf_2_3,Polysacc_deac_1
TLS3_k127_1758272_0	1120948.KB903240_gene3767	0.0	1475.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,4DXSA@85010|Pseudonocardiales	201174|Actinobacteria	L	DEAD DEAH box helicase	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
TLS3_k127_1758272_1	1211815.CBYP010000060_gene3086	2.534e-52	186.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4ESXC@85013|Frankiales	201174|Actinobacteria	I	PFAM Diacylglycerol kinase, catalytic	dagK	GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
TLS3_k127_1765447_2	1122939.ATUD01000003_gene3641	8.905e-15	76.0	COG4572@1|root,COG4572@2|Bacteria,2IMHQ@201174|Actinobacteria,4CTFN@84995|Rubrobacteria	84995|Rubrobacteria	S	ChaB	-	-	-	-	-	-	-	-	-	-	-	-	ChaB
TLS3_k127_1765447_0	1120948.KB903229_gene5271	3.414e-58	214.0	COG1266@1|root,COG1266@2|Bacteria,2HZR1@201174|Actinobacteria,4EDD8@85010|Pseudonocardiales	2|Bacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
TLS3_k127_1765447_1	287986.DV20_36765	1.878e-23	106.0	2A05I@1|root,30N8A@2|Bacteria,2ITFD@201174|Actinobacteria,4E617@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1767779_1	1120948.KB903243_gene2540	2.765e-164	524.0	COG0477@1|root,COG0477@2|Bacteria,2GKFJ@201174|Actinobacteria,4DY6H@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	entS_1	-	-	-	-	-	-	-	-	-	-	-	MFS_3
TLS3_k127_1767779_0	1120948.KB903225_gene5538	1.835e-213	673.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4DXY1@85010|Pseudonocardiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_1767779_2	1120948.KB903243_gene2536	1.191e-102	341.0	COG2017@1|root,COG2017@2|Bacteria,2GJ0H@201174|Actinobacteria,4DZ64@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Aldose 1-epimerase	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
TLS3_k127_1774137_7	526225.Gobs_2572	3.133e-18	88.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4ETGG@85013|Frankiales	201174|Actinobacteria	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Guanylate_cyc,NB-ARC,Trans_reg_C
TLS3_k127_1774137_5	1461694.ATO9_11065	1.571e-76	272.0	COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,2TWSB@28211|Alphaproteobacteria,2PCWC@252301|Oceanicola	28211|Alphaproteobacteria	Q	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
TLS3_k127_1774137_6	2074.JNYD01000011_gene104	1.528e-33	150.0	COG0454@1|root,COG0456@2|Bacteria,2I3RS@201174|Actinobacteria,4EF7M@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_1774137_2	1429046.RR21198_4072	1.06e-133	432.0	COG0500@1|root,COG2226@2|Bacteria,2GM2N@201174|Actinobacteria,4FX7V@85025|Nocardiaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
TLS3_k127_1774137_3	1120948.KB903225_gene5603	6.208e-105	354.0	COG0189@1|root,COG0189@2|Bacteria,2HI2Z@201174|Actinobacteria,4DXM1@85010|Pseudonocardiales	201174|Actinobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	GSH-S_ATP
TLS3_k127_1774137_4	1120948.KB903225_gene5604	8.766e-90	319.0	COG1990@1|root,COG1990@2|Bacteria,2HEY8@201174|Actinobacteria,4DZ03@85010|Pseudonocardiales	201174|Actinobacteria	S	peptidyl-tRNA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PTH2
TLS3_k127_1774137_1	1120948.KB903225_gene5605	1.095e-189	601.0	COG0560@1|root,COG0560@2|Bacteria,2GJDH@201174|Actinobacteria,4E15F@85010|Pseudonocardiales	201174|Actinobacteria	ET	phosphoserine phosphatase	serB	GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0004722,GO:0005488,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016597,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031406,GO:0036094,GO:0036211,GO:0040007,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	iNJ661.Rv3042c	ACT_6,HAD
TLS3_k127_1774137_0	1120948.KB903225_gene5606	5.175e-200	623.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4DX7G@85010|Pseudonocardiales	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
TLS3_k127_1777554_5	1120934.KB894428_gene1849	9.707e-26	122.0	COG3209@1|root,COG3209@2|Bacteria,2H52B@201174|Actinobacteria	201174|Actinobacteria	M	HNH/Endo VII superfamily nuclease toxins	-	-	-	-	-	-	-	-	-	-	-	-	RHS,Tox-HNH-EHHH
TLS3_k127_1777554_8	1449346.JQMO01000002_gene1614	4.51e-18	94.0	COG1396@1|root,COG3170@1|root,COG1396@2|Bacteria,COG3170@2|Bacteria,2H8D5@201174|Actinobacteria	201174|Actinobacteria	NU	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1777554_7	1348663.KCH_75920	6.512e-20	102.0	COG3170@1|root,COG3170@2|Bacteria,2H8D5@201174|Actinobacteria,2M1ZQ@2063|Kitasatospora	201174|Actinobacteria	NU	ADP-ribosyltransferase exoenzyme	-	-	-	-	-	-	-	-	-	-	-	-	ADPrib_exo_Tox
TLS3_k127_1777554_6	1449353.JQMQ01000005_gene1236	1.77e-24	112.0	291I2@1|root,2ZP4K@2|Bacteria,2GJ3E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1777554_1	1120948.KB903217_gene1120	5.029e-118	393.0	COG4585@1|root,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4DXU8@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TLS3_k127_1777554_2	1120948.KB903217_gene1119	7.57e-89	305.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4DYI0@85010|Pseudonocardiales	201174|Actinobacteria	KT	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_1777554_3	1032480.MLP_45450	2.952e-65	230.0	2DHBJ@1|root,322ZG@2|Bacteria,2I85Y@201174|Actinobacteria,4DVQU@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1777554_4	1123024.AUII01000002_gene1113	7.627e-57	203.0	COG1695@1|root,COG1695@2|Bacteria,2IE7S@201174|Actinobacteria,4E53K@85010|Pseudonocardiales	201174|Actinobacteria	K	Virulence activator alpha C-term	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
TLS3_k127_1777554_0	1120948.KB903218_gene1772	2.42e-125	407.0	COG3670@1|root,COG3670@2|Bacteria,2GK7D@201174|Actinobacteria,4DX5S@85010|Pseudonocardiales	201174|Actinobacteria	Q	Retinal pigment epithelial membrane protein	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
TLS3_k127_1789854_2	1120948.KB903240_gene3954	3.554e-165	532.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4E01H@85010|Pseudonocardiales	201174|Actinobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
TLS3_k127_1789854_3	1120948.KB903240_gene3953	2.834e-94	317.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4DYKI@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Shikimate dehydrogenase substrate binding	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2552c	Shikimate_DH,Shikimate_dh_N
TLS3_k127_1789854_5	1123023.JIAI01000009_gene988	4.78e-31	130.0	COG1989@1|root,COG1989@2|Bacteria,2HH3V@201174|Actinobacteria,4E637@85010|Pseudonocardiales	201174|Actinobacteria	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	Peptidase_A24
TLS3_k127_1789854_0	1120948.KB903240_gene3951	2.437e-203	639.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4DZB5@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2540c	Chorismate_synt
TLS3_k127_1789854_4	1120948.KB903240_gene3950	1.649e-64	244.0	COG0703@1|root,COG0703@2|Bacteria,2GRFW@201174|Actinobacteria,4E489@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
TLS3_k127_1789854_1	1120948.KB903240_gene3949	4.868e-170	544.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,4DY4R@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
TLS3_k127_1802911_1	1120948.KB903217_gene1107	1.564e-124	410.0	COG1330@1|root,COG1330@2|Bacteria,2GNVB@201174|Actinobacteria,4E8FA@85010|Pseudonocardiales	201174|Actinobacteria	L	Exodeoxyribonuclease V, gamma subunit	recC	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
TLS3_k127_1802911_0	1120948.KB903217_gene1108	5.854e-306	959.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria,4EA4P@85010|Pseudonocardiales	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	recB	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
TLS3_k127_1803753_1	1120948.KB903246_gene3190	6.173e-122	395.0	COG1960@1|root,COG1960@2|Bacteria,2IEV9@201174|Actinobacteria,4E89V@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
TLS3_k127_1803753_0	1120948.KB903246_gene3191	4.835e-235	730.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4E073@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_1803753_2	1120948.KB903246_gene3192	3.014e-100	338.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,4DZKM@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
TLS3_k127_1813604_5	1120948.KB903246_gene3272	6.216e-15	79.0	COG1633@1|root,COG1633@2|Bacteria,2I2E1@201174|Actinobacteria,4EF6U@85010|Pseudonocardiales	201174|Actinobacteria	S	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like	-	-	-	-	-	-	-	-	-	-	-	-	MiaE_2
TLS3_k127_1813604_4	1120948.KB903246_gene3271	2.946e-28	116.0	2E3M2@1|root,32YJA@2|Bacteria,2GQQW@201174|Actinobacteria,4E6SK@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3107
TLS3_k127_1813604_2	1120948.KB903246_gene3270	1.309e-101	334.0	COG1309@1|root,COG1309@2|Bacteria,2GVM5@201174|Actinobacteria,4DZU6@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_1813604_1	1120948.KB903246_gene3269	5.192e-103	348.0	COG2267@1|root,COG2267@2|Bacteria,2GM96@201174|Actinobacteria,4DYFE@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
TLS3_k127_1813604_3	1120948.KB903246_gene3268	1.773e-95	345.0	COG5479@1|root,COG5479@2|Bacteria,2GMJR@201174|Actinobacteria,4DZJA@85010|Pseudonocardiales	201174|Actinobacteria	M	Protein of unknown function (DUF3152)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3152
TLS3_k127_1813604_0	1120948.KB903246_gene3267	1.053e-239	745.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4DXZR@85010|Pseudonocardiales	201174|Actinobacteria	HP	Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0019344,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
TLS3_k127_1816956_1	1120948.KB903243_gene2582	4.41e-161	515.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4DX4V@85010|Pseudonocardiales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
TLS3_k127_1816956_2	1120948.KB903243_gene2585	6.169e-158	505.0	COG1226@1|root,COG1226@2|Bacteria,2GKB8@201174|Actinobacteria,4E0P9@85010|Pseudonocardiales	201174|Actinobacteria	P	K transport system, NAD-binding component	kch	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
TLS3_k127_1816956_0	1120948.KB903243_gene2468	4.718e-267	834.0	COG1012@1|root,COG1012@2|Bacteria,2HZI5@201174|Actinobacteria,4E8NA@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
TLS3_k127_1816956_3	1056816.JAFQ01000004_gene6787	1.023e-146	471.0	COG0739@1|root,COG0739@2|Bacteria,2GNJB@201174|Actinobacteria,4G999@85025|Nocardiaceae	201174|Actinobacteria	M	Domain of unknown function (DUF4185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4185
TLS3_k127_1816956_5	1120948.KB903240_gene4055	1.103e-109	366.0	2CC4I@1|root,2Z8PZ@2|Bacteria,2GZQC@201174|Actinobacteria,4DXHX@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1816956_4	1120948.KB903217_gene922	3.734e-118	397.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4DZBG@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
TLS3_k127_1846191_3	1120948.KB903217_gene1629	8.599e-10	68.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4E4AY@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
TLS3_k127_1846191_1	1150864.MILUP08_45263	2.159e-48	181.0	COG3795@1|root,COG3795@2|Bacteria,2IQMR@201174|Actinobacteria,4DFYQ@85008|Micromonosporales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
TLS3_k127_1846191_0	1306174.JODP01000003_gene2083	2.906e-142	468.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_1846191_2	1068980.ARVW01000001_gene8258	1.346e-30	127.0	COG3087@1|root,COG3087@2|Bacteria,2IM9C@201174|Actinobacteria,4EBBY@85010|Pseudonocardiales	201174|Actinobacteria	D	Putative transmembrane protein (PGPGW)	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
TLS3_k127_1861422_7	1120948.KB903217_gene954	4.391e-26	111.0	COG1807@1|root,COG1807@2|Bacteria,2GK3Q@201174|Actinobacteria,4DZ07@85010|Pseudonocardiales	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_1861422_2	1120948.KB903217_gene955	1.415e-112	368.0	28J7N@1|root,2Z931@2|Bacteria,2IBUF@201174|Actinobacteria	201174|Actinobacteria	L	Restriction endonuclease BglII	-	-	-	-	-	-	-	-	-	-	-	-	Endonuc-BglII
TLS3_k127_1861422_0	1120948.KB903217_gene956	2.226e-126	411.0	COG4725@1|root,COG4725@2|Bacteria,2IIR3@201174|Actinobacteria,4E8RK@85010|Pseudonocardiales	201174|Actinobacteria	KT	MT-A70	-	-	-	-	-	-	-	-	-	-	-	-	MT-A70
TLS3_k127_1861422_6	1120948.KB903217_gene957	1.706e-29	124.0	2E4I7@1|root,2ZPF0@2|Bacteria,2GYY2@201174|Actinobacteria,4EDAF@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1861422_4	1120948.KB903217_gene958	1.449e-55	202.0	COG5485@1|root,COG5485@2|Bacteria,2INMM@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
TLS3_k127_1861422_3	1120948.KB903217_gene959	3.983e-93	309.0	2AK5H@1|root,31AVD@2|Bacteria,2IP7U@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1861422_1	1120948.KB903217_gene961	2.952e-126	407.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4DY9S@85010|Pseudonocardiales	201174|Actinobacteria	E	methionine	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
TLS3_k127_1861422_5	1120948.KB903217_gene963	2.531e-49	180.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria,4DXWP@85010|Pseudonocardiales	201174|Actinobacteria	P	flavoprotein involved in K transport	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,K_oxygenase,NAD_binding_8,Pyr_redox_2,Pyr_redox_3
TLS3_k127_1892924_6	1120948.KB903219_gene626	4.174e-12	72.0	COG5340@1|root,COG5340@2|Bacteria,2I4A3@201174|Actinobacteria	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1892924_1	1120948.KB903246_gene3387	8.143e-207	649.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4DX8J@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the thiolase family	fadA2	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
TLS3_k127_1892924_0	1120948.KB903246_gene3386	4.613e-252	783.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4E0ZQ@85010|Pseudonocardiales	201174|Actinobacteria	EK	Cystathionine beta-synthase	cbs	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
TLS3_k127_1892924_2	1120948.KB903246_gene3385	1.016e-191	604.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4DX61@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Cys Met metabolism	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
TLS3_k127_1892924_5	1194972.MVAC_08619	4.376e-71	248.0	COG3467@1|root,COG3467@2|Bacteria,2IFCX@201174|Actinobacteria,238P1@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
TLS3_k127_1892924_3	1120948.KB903246_gene3383	1.708e-168	544.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DYHI@85010|Pseudonocardiales	201174|Actinobacteria	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
TLS3_k127_1892924_4	1120948.KB903246_gene3382	2.891e-97	319.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4E353@85010|Pseudonocardiales	201174|Actinobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
TLS3_k127_1904020_0	65497.JODV01000003_gene4550	1.783e-144	468.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4DXM8@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferases group 1	pimB	GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_1904020_1	1380393.JHVP01000004_gene648	8.608e-137	441.0	COG2267@1|root,COG2267@2|Bacteria,2IBXP@201174|Actinobacteria	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_1904020_2	1120948.KB903248_gene4314	1.625e-105	359.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,4E2J0@85010|Pseudonocardiales	201174|Actinobacteria	M	Cell wall-associated hydrolase, invasion-associated protein	-	GO:0005575,GO:0005576	-	ko:K21471,ko:K21473	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
TLS3_k127_1913338_0	1120948.KB903245_gene3559	6.828e-159	503.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4DXVY@85010|Pseudonocardiales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
TLS3_k127_1913338_1	1120948.KB903245_gene3545	2.155e-155	523.0	COG2133@1|root,COG2133@2|Bacteria,2GISM@201174|Actinobacteria,4DYK8@85010|Pseudonocardiales	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
TLS3_k127_1913338_2	1120948.KB903245_gene3544	4.537e-140	450.0	COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,4DYSI@85010|Pseudonocardiales	201174|Actinobacteria	EH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TLS3_k127_1913338_3	653045.Strvi_1127	4.972e-78	265.0	COG1309@1|root,COG1309@2|Bacteria,2IBKZ@201174|Actinobacteria	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
TLS3_k127_1919852_1	1120948.KB903246_gene3374	8.204e-121	402.0	COG4805@1|root,COG4805@2|Bacteria,2GJQT@201174|Actinobacteria,4DYBW@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1919852_0	1120948.KB903246_gene3373	1.066e-193	612.0	COG1875@1|root,COG1875@2|Bacteria,2GK8U@201174|Actinobacteria,4DZA7@85010|Pseudonocardiales	201174|Actinobacteria	T	PFAM PhoH-like protein	phoH2	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
TLS3_k127_1941803_1	1120948.KB903220_gene38	5.673e-114	379.0	COG0476@1|root,COG0476@2|Bacteria,2HQ2F@201174|Actinobacteria,4DZR7@85010|Pseudonocardiales	201174|Actinobacteria	H	ThiF family	moeY	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0061503,GO:0061504,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	-	-	-	-	-	-	-	-	-	Nitroreductase,ThiF
TLS3_k127_1941803_0	1120948.KB903220_gene39	1.995e-244	789.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DYN9@85010|Pseudonocardiales	201174|Actinobacteria	T	Diguanylate cyclase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009165,GO:0009166,GO:0009187,GO:0009190,GO:0009214,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0052621,GO:0055086,GO:0071111,GO:0071704,GO:0071944,GO:0090407,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS_4,PAS_9
TLS3_k127_1941803_2	883126.HMPREF9710_02800	1.744e-111	375.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Lipase_GDSL_2
TLS3_k127_1941803_3	58344.JOEL01000044_gene886	5.857e-09	58.0	COG2267@1|root,COG2267@2|Bacteria,2GPA8@201174|Actinobacteria	201174|Actinobacteria	I	hydrolase	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
TLS3_k127_1944841_5	469383.Cwoe_5780	8.86e-06	48.0	COG3243@1|root,COG3243@2|Bacteria,2GP7I@201174|Actinobacteria,4CQCE@84995|Rubrobacteria	84995|Rubrobacteria	I	Alpha beta hydrolase	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Abhydrolase_1
TLS3_k127_1944841_3	1120948.KB903248_gene4367	1.424e-57	208.0	2E4IQ@1|root,32ZDS@2|Bacteria,2IJ3H@201174|Actinobacteria,4E43H@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1944841_4	1089544.KB912942_gene2382	1.406e-28	126.0	COG3224@1|root,COG3224@2|Bacteria,2GQKQ@201174|Actinobacteria,4E6P1@85010|Pseudonocardiales	201174|Actinobacteria	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD
TLS3_k127_1944841_0	1120948.KB903240_gene4082	1.409e-66	234.0	COG0500@1|root,COG0500@2|Bacteria,2GX4K@201174|Actinobacteria,4E503@85010|Pseudonocardiales	201174|Actinobacteria	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_1944841_1	1068980.ARVW01000001_gene4078	1.051e-65	232.0	COG5398@1|root,COG5398@2|Bacteria,2H90I@201174|Actinobacteria,4E3UY@85010|Pseudonocardiales	201174|Actinobacteria	P	Heme oxygenase	hmuO	-	1.14.15.20	ko:K21480	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R11579	RC01270	ko00000,ko00001,ko01000	-	-	-	Heme_oxygenase
TLS3_k127_1944841_2	101510.RHA1_ro01543	2.729e-58	205.0	COG3576@1|root,COG3576@2|Bacteria,2I3RW@201174|Actinobacteria,4G0JU@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
TLS3_k127_194832_1	1120948.KB903240_gene4075	7.381e-133	431.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4E1CX@85010|Pseudonocardiales	201174|Actinobacteria	E	ABC-type branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
TLS3_k127_194832_5	1120948.KB903240_gene4070	1.832e-13	82.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4DZ0W@85010|Pseudonocardiales	201174|Actinobacteria	E	Branched-chain amino acid transport	livF	-	-	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
TLS3_k127_194832_2	675635.Psed_0701	9.718e-124	419.0	COG0654@1|root,COG0654@2|Bacteria,2GKUZ@201174|Actinobacteria,4DX8V@85010|Pseudonocardiales	201174|Actinobacteria	CH	FAD binding domain	sppF	-	1.14.13.200	ko:K14672,ko:K15972	ko01057,ko01130,map01057,map01130	M00783	R06704,R10954	RC02681	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	FAD_binding_3
TLS3_k127_194832_0	2074.JNYD01000032_gene6470	9.433e-172	585.0	COG2197@1|root,COG2197@2|Bacteria,2I3SK@201174|Actinobacteria,4EF8T@85010|Pseudonocardiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_194832_3	526225.Gobs_3758	2.153e-77	279.0	COG2070@1|root,COG2070@2|Bacteria,2IN9Q@201174|Actinobacteria,4EX7F@85013|Frankiales	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
TLS3_k127_194832_4	1120948.KB903240_gene4067	1.191e-56	204.0	COG2050@1|root,COG2050@2|Bacteria,2IKTU@201174|Actinobacteria,4E4JR@85010|Pseudonocardiales	201174|Actinobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
TLS3_k127_1956643_0	1120948.KB903244_gene3002	0.0	1937.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4E13K@85010|Pseudonocardiales	201174|Actinobacteria	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
TLS3_k127_1964860_4	1120948.KB903229_gene5138	1.052e-11	66.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4E2XM@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_1964860_0	1120948.KB903232_gene4665	2.073e-319	996.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4DZ94@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
TLS3_k127_1964860_3	1120948.KB903229_gene5140	5.928e-21	98.0	COG2153@1|root,COG2153@2|Bacteria,2IFAM@201174|Actinobacteria,4E4VP@85010|Pseudonocardiales	201174|Actinobacteria	S	Acetyltransferase (GNAT) domain	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
TLS3_k127_1964860_5	1120948.KB903229_gene5140	3.407e-07	57.0	COG2153@1|root,COG2153@2|Bacteria,2IFAM@201174|Actinobacteria,4E4VP@85010|Pseudonocardiales	201174|Actinobacteria	S	Acetyltransferase (GNAT) domain	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
TLS3_k127_1964860_1	1120948.KB903229_gene5141	5.949e-86	291.0	28PSZ@1|root,2ZCEC@2|Bacteria,2GMRM@201174|Actinobacteria,4DZ6M@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1969154_0	1120948.KB903217_gene1637	2.948e-174	561.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4DX5D@85010|Pseudonocardiales	201174|Actinobacteria	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TLS3_k127_1970_2	1440774.Y900_011485	8.345e-194	606.0	COG0069@1|root,COG0069@2|Bacteria,2GME2@201174|Actinobacteria,23619@1762|Mycobacteriaceae	201174|Actinobacteria	E	Belongs to the glutamate synthase family	gltB_3	-	2.1.1.21	ko:K22083	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	Glu_synthase
TLS3_k127_1970_7	2074.JNYD01000030_gene6605	2.421e-92	308.0	COG1396@1|root,COG1396@2|Bacteria,2GXAS@201174|Actinobacteria,4EF8S@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
TLS3_k127_1970_3	471857.Svir_08600	1.492e-113	376.0	COG0182@1|root,COG0182@2|Bacteria,2GJJA@201174|Actinobacteria,4DZKT@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
TLS3_k127_1970_0	795955.AFRW01000117_gene1180	0.0	1128.0	COG0243@1|root,COG0243@2|Bacteria,2GJCK@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	bisC	-	1.8.5.3,1.97.1.9	ko:K07306,ko:K07309,ko:K07310,ko:K08351	ko00450,ko00780,ko00920,ko01100,map00450,map00780,map00920,map01100	-	R07229,R09501,R10127	RC02420,RC02555,RC03056	ko00000,ko00001,ko01000,ko02000	5.A.3.3,5.A.3.4	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
TLS3_k127_1970_6	1120948.KB903243_gene2382	2.284e-110	366.0	COG3217@1|root,COG3217@2|Bacteria,2GND9@201174|Actinobacteria,4E4QC@85010|Pseudonocardiales	201174|Actinobacteria	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
TLS3_k127_1970_8	1120948.KB903243_gene2381	2.221e-52	203.0	COG1720@1|root,COG1720@2|Bacteria,2IKKT@201174|Actinobacteria,4E4PZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
TLS3_k127_1970_5	1120948.KB903243_gene2380	1.283e-112	406.0	COG2072@1|root,COG2072@2|Bacteria,2GKYU@201174|Actinobacteria,4EA04@85010|Pseudonocardiales	201174|Actinobacteria	P	Flavin-binding monooxygenase-like	-	-	1.14.13.226	ko:K18371	ko00640,map00640	-	R10704	RC03250	ko00000,ko00001,ko01000	-	-	-	FMO-like,NAD_binding_8,Pyr_redox_3
TLS3_k127_1970_1	1179773.BN6_36330	0.0	1070.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4DYSY@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,DUF2075,UvrD_C_2,Viral_helicase1
TLS3_k127_1970_4	1120948.KB903227_gene4835	5.69e-113	381.0	COG3861@1|root,COG3861@2|Bacteria,2II0U@201174|Actinobacteria,4E2J5@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF2382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2382,PRC
TLS3_k127_1973751_10	1317118.ATO8_20789	5.771e-13	73.0	COG0838@1|root,COG0838@2|Bacteria,1PPP2@1224|Proteobacteria,2U7SM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q4
TLS3_k127_1973751_7	2074.JNYD01000002_gene5475	6.37e-58	223.0	28NMB@1|root,2ZBMW@2|Bacteria,2HXE3@201174|Actinobacteria,4E3YT@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1973751_5	675635.Psed_6867	1.849e-118	406.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,4DY26@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH ubiquinone oxidoreductase subunit 1	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
TLS3_k127_1973751_6	2074.JNYD01000002_gene5473	9.086e-59	223.0	COG0839@1|root,COG0839@2|Bacteria,2IBCM@201174|Actinobacteria,4E3IA@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the complex I subunit 6 family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q3
TLS3_k127_1973751_8	2074.JNYD01000002_gene5472	3.239e-37	151.0	COG0713@1|root,COG0713@2|Bacteria,2IHNW@201174|Actinobacteria,4E64K@85010|Pseudonocardiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K05576	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q2
TLS3_k127_1973751_2	675635.Psed_6864	1.396e-188	606.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4DYB8@85010|Pseudonocardiales	201174|Actinobacteria	CP	NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M,Proton_antipo_N
TLS3_k127_1973751_0	455632.SGR_786	9.828e-224	717.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,41C2R@629295|Streptomyces griseus group	201174|Actinobacteria	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TLS3_k127_1973751_3	2074.JNYD01000002_gene5469	1.387e-158	514.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4E1MP@85010|Pseudonocardiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
TLS3_k127_1973751_9	1206733.BAGC01000050_gene2660	5.323e-28	116.0	29X4H@1|root,30ITE@2|Bacteria,2GYF3@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
TLS3_k127_1973751_11	1463917.JODC01000007_gene7582	4.207e-11	72.0	COG0640@1|root,COG0640@2|Bacteria,2IM1K@201174|Actinobacteria	201174|Actinobacteria	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
TLS3_k127_1973751_1	1120948.KB903243_gene2414	2.984e-204	644.0	COG1680@1|root,COG1680@2|Bacteria,2H2SY@201174|Actinobacteria,4DYID@85010|Pseudonocardiales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	ko:K18372	ko00640,map00640	-	R10705	RC00460,RC00461	ko00000,ko00001,ko01000	-	-	-	Beta-lactamase
TLS3_k127_1973751_4	526225.Gobs_1837	6.335e-149	480.0	COG2072@1|root,COG2072@2|Bacteria,2GKYU@201174|Actinobacteria,4ETWH@85013|Frankiales	201174|Actinobacteria	C	Flavin-binding monooxygenase-like	-	-	1.14.13.22,1.14.13.226	ko:K03379,ko:K18371	ko00640,ko00930,ko01120,ko01220,map00640,map00930,map01120,map01220	-	R02231,R06622,R10704	RC00662,RC01550,RC03250	ko00000,ko00001,ko01000	-	-	-	FMO-like,NAD_binding_8,Pyr_redox_3
TLS3_k127_1975910_3	1120948.KB903240_gene3781	4.894e-91	299.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4DZ1H@85010|Pseudonocardiales	201174|Actinobacteria	O	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
TLS3_k127_1975910_1	1120948.KB903240_gene3780	1.553e-189	599.0	COG1075@1|root,COG1075@2|Bacteria,2IBAW@201174|Actinobacteria,4E8GZ@85010|Pseudonocardiales	201174|Actinobacteria	S	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,DUF676,PGAP1
TLS3_k127_1975910_2	1120948.KB903240_gene3779	1.414e-120	421.0	COG0477@1|root,COG2814@2|Bacteria,2GJK6@201174|Actinobacteria,4DY6I@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Drug resistance transporter Bcr CflA subfamily	bcr	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
TLS3_k127_1975910_0	1120948.KB903240_gene3778	7.952e-255	789.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4DZ25@85010|Pseudonocardiales	201174|Actinobacteria	S	proteasome accessory factor PafA2	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
TLS3_k127_1977791_4	356851.JOAN01000007_gene4023	4.898e-15	81.0	2E8C8@1|root,332QW@2|Bacteria,2IP3X@201174|Actinobacteria,4DEPD@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_1977791_5	1127134.NOCYR_3403	1.83e-08	66.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4FWRF@85025|Nocardiaceae	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_1977791_2	479432.Sros_2432	6.251e-197	627.0	COG3835@1|root,COG3835@2|Bacteria,2I3H3@201174|Actinobacteria,4ER15@85012|Streptosporangiales	201174|Actinobacteria	KT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
TLS3_k127_1977791_1	66377.JOBH01000012_gene4369	3.745e-207	663.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria	201174|Actinobacteria	M	mandelate racemase muconate lactonizing	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
TLS3_k127_1977791_3	1343740.M271_45780	2.339e-84	288.0	COG2186@1|root,COG2186@2|Bacteria,2GJ82@201174|Actinobacteria	201174|Actinobacteria	K	gntR family	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
TLS3_k127_1977791_0	1123023.JIAI01000001_gene6498	7.923e-268	842.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4DX88@85010|Pseudonocardiales	201174|Actinobacteria	EG	Belongs to the IlvD Edd family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
TLS3_k127_2013140_4	1223523.H340_26369	1.162e-13	70.0	COG1917@1|root,COG1917@2|Bacteria,2IIQY@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,Cupin_3
TLS3_k127_2013140_3	318424.EU78_25215	5.326e-95	325.0	COG1835@1|root,COG1835@2|Bacteria,2GN56@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS3_k127_2013140_2	330084.JNYZ01000026_gene2609	1.45e-106	359.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4E0A0@85010|Pseudonocardiales	201174|Actinobacteria	M	Capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
TLS3_k127_2013140_0	1120948.KB903247_gene4425	0.0	1078.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4E23C@85010|Pseudonocardiales	201174|Actinobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
TLS3_k127_2013140_1	1120948.KB903247_gene4426	1.389e-235	733.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4E24C@85010|Pseudonocardiales	201174|Actinobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS3_k127_2016158_3	1120948.KB903245_gene3502	1.643e-59	213.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4DZMJ@85010|Pseudonocardiales	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
TLS3_k127_2016158_4	1120948.KB903245_gene3501	3.025e-53	199.0	COG1920@1|root,COG1920@2|Bacteria,2HJNU@201174|Actinobacteria,4E3VX@85010|Pseudonocardiales	201174|Actinobacteria	S	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC,NTP_transf_3
TLS3_k127_2016158_1	1120948.KB903245_gene3500	3.467e-98	327.0	COG0204@1|root,COG0204@2|Bacteria,2GKVA@201174|Actinobacteria,4DXRJ@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TLS3_k127_2016158_0	1120948.KB903245_gene3499	3.91e-147	505.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria,4DXPW@85010|Pseudonocardiales	201174|Actinobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
TLS3_k127_2016158_5	1120948.KB903245_gene3498	5.062e-45	169.0	COG2172@1|root,COG2172@2|Bacteria,2GRSR@201174|Actinobacteria,4ED4K@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
TLS3_k127_2016158_2	1120948.KB903245_gene3497	1.689e-75	262.0	COG3467@1|root,COG3467@2|Bacteria,2GJ76@201174|Actinobacteria,4E32Q@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
TLS3_k127_2016158_6	1120948.KB903245_gene3496	4.953e-25	108.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4DY3D@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator with HTH domain and aminotransferase domain	pdxR	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
TLS3_k127_2024791_1	1120948.KB903217_gene1173	8.186e-59	215.0	COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria,4E2UD@85010|Pseudonocardiales	201174|Actinobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
TLS3_k127_2024791_0	1120948.KB903217_gene1174	1.121e-157	504.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4DYUX@85010|Pseudonocardiales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
TLS3_k127_2037104_1	1123023.JIAI01000002_gene4681	2.458e-70	263.0	COG1403@1|root,COG1403@2|Bacteria,2INVR@201174|Actinobacteria	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
TLS3_k127_2037104_0	1122611.KB903959_gene4202	1.716e-88	297.0	COG4312@1|root,COG4312@2|Bacteria,2GIVC@201174|Actinobacteria,4EQV9@85012|Streptosporangiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
TLS3_k127_2037104_2	33876.JNXY01000031_gene3131	1.42e-18	86.0	2EGSG@1|root,33AIJ@2|Bacteria,2GWW3@201174|Actinobacteria,4DGAW@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HHH_5
TLS3_k127_2040632_1	1032480.MLP_19420	5.593e-67	233.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	5.3.3.19	ko:K19547	ko01130,map01130	M00787	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2
TLS3_k127_2040632_3	1032480.MLP_19430	7.319e-53	192.0	COG1846@1|root,COG1846@2|Bacteria,2INEU@201174|Actinobacteria,4DWUH@85009|Propionibacteriales	201174|Actinobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
TLS3_k127_2040632_2	1179773.BN6_75270	2.543e-62	224.0	COG3832@1|root,COG3832@2|Bacteria,2IHTJ@201174|Actinobacteria,4E53R@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_2040632_4	110319.CF8_0720	3.59e-47	178.0	COG0640@1|root,COG0640@2|Bacteria,2IKQY@201174|Actinobacteria,4DQZ4@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
TLS3_k127_2040632_0	1120948.KB903217_gene1161	3.461e-123	402.0	COG0657@1|root,COG0657@2|Bacteria,2IHMG@201174|Actinobacteria,4EEQN@85010|Pseudonocardiales	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
TLS3_k127_2040632_5	1120948.KB903217_gene1160	2.541e-42	175.0	COG3953@1|root,COG3953@2|Bacteria,2GTVM@201174|Actinobacteria,4EBKT@85010|Pseudonocardiales	201174|Actinobacteria	S	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
TLS3_k127_2043048_2	211114.JOEF01000013_gene4904	6.486e-20	91.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4DXNY@85010|Pseudonocardiales	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
TLS3_k127_2043048_1	1179773.BN6_69830	2.89e-30	124.0	COG2740@1|root,COG2740@2|Bacteria,2GQH0@201174|Actinobacteria,4E6Q8@85010|Pseudonocardiales	201174|Actinobacteria	K	nucleic-acid-binding protein implicated in transcription termination	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
TLS3_k127_2043048_0	1120948.KB903244_gene3072	3.293e-163	523.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4E02Y@85010|Pseudonocardiales	201174|Actinobacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
TLS3_k127_2050190_0	1120948.KB903246_gene3223	8.991e-235	740.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria,4DYK7@85010|Pseudonocardiales	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD3	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
TLS3_k127_2050190_6	1112204.GPOL_c33630	4.475e-24	114.0	COG3695@1|root,COG3695@2|Bacteria,2GQMD@201174|Actinobacteria,4GEEP@85026|Gordoniaceae	201174|Actinobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
TLS3_k127_2050190_2	1120948.KB903246_gene3230	1.078e-157	506.0	COG0438@1|root,COG0438@2|Bacteria,2GKX4@201174|Actinobacteria,4E2H9@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_2050190_4	1120948.KB903246_gene3231	6.559e-130	431.0	COG0388@1|root,COG0388@2|Bacteria,2GS3V@201174|Actinobacteria,4DZ6T@85010|Pseudonocardiales	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
TLS3_k127_2050190_3	1120948.KB903246_gene3232	8.923e-150	492.0	COG0388@1|root,COG0388@2|Bacteria,2GKRJ@201174|Actinobacteria,4DZ74@85010|Pseudonocardiales	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
TLS3_k127_2050190_1	1120948.KB903246_gene3233	8.32e-194	623.0	COG2144@1|root,COG2153@1|root,COG2144@2|Bacteria,COG2153@2|Bacteria,2GM78@201174|Actinobacteria,4E1YB@85010|Pseudonocardiales	201174|Actinobacteria	S	AIR synthase related protein, C-terminal domain	thiL_1	-	-	ko:K07123	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C,Acetyltransf_1,Acetyltransf_10
TLS3_k127_2050190_5	1120948.KB903246_gene3234	1.436e-72	246.0	COG0320@1|root,COG0320@2|Bacteria,2I3UP@201174|Actinobacteria,4EFEZ@85010|Pseudonocardiales	201174|Actinobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TLS3_k127_2056492_0	1120948.KB903243_gene2359	4.793e-153	511.0	COG0642@1|root,COG2205@2|Bacteria,2GM17@201174|Actinobacteria,4E0HJ@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	mprB	GO:0000160,GO:0003674,GO:0003824,GO:0004721,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023052,GO:0035556,GO:0036211,GO:0040007,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K07653	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_2056492_1	1120948.KB903243_gene2358	1.646e-128	436.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4DXXX@85010|Pseudonocardiales	201174|Actinobacteria	O	PDZ domain (Also known as DHR or GLGF)	pepD	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
TLS3_k127_2056492_3	1120948.KB903243_gene2357	7.706e-85	299.0	COG0500@1|root,COG0500@2|Bacteria,2I2R3@201174|Actinobacteria,4E3W2@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	MetW,Methyltransf_11,Methyltransf_23,Methyltransf_25
TLS3_k127_2056492_4	1120948.KB903243_gene2356	2.787e-71	259.0	COG3222@1|root,COG3222@2|Bacteria,2GN3B@201174|Actinobacteria,4E3XE@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
TLS3_k127_2056492_2	1120948.KB903243_gene2355	9.003e-113	369.0	COG1215@1|root,COG1215@2|Bacteria,2GMMV@201174|Actinobacteria,4DZEA@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_2068141_5	1120948.KB903244_gene3073	1.437e-51	189.0	COG0779@1|root,COG0779@2|Bacteria,2I9BT@201174|Actinobacteria,4E3T2@85010|Pseudonocardiales	201174|Actinobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
TLS3_k127_2068141_6	1120948.KB903244_gene3075	1.415e-34	146.0	2DSVA@1|root,33HJF@2|Bacteria,2I867@201174|Actinobacteria,4EECB@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4439)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4439
TLS3_k127_2068141_2	1120948.KB903244_gene3078	1.014e-85	301.0	2C2EJ@1|root,33KY9@2|Bacteria,2GTG8@201174|Actinobacteria,4E652@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2068141_1	1120948.KB903244_gene3079	1.875e-100	335.0	COG0300@1|root,COG0300@2|Bacteria,2I2VP@201174|Actinobacteria,4E5V9@85010|Pseudonocardiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_2068141_3	1120948.KB903244_gene3080	3.384e-73	250.0	COG0432@1|root,COG0432@2|Bacteria,2IHWS@201174|Actinobacteria,4E3D5@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Uncharacterised protein family UPF0047	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0047
TLS3_k127_2068141_0	1120948.KB903244_gene3084	1.216e-114	383.0	COG1940@1|root,COG1940@2|Bacteria,2GPEI@201174|Actinobacteria,4E56W@85010|Pseudonocardiales	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
TLS3_k127_2068141_4	649831.L083_6138	1.069e-57	211.0	COG0637@1|root,COG0637@2|Bacteria,2GNX0@201174|Actinobacteria,4DDGB@85008|Micromonosporales	201174|Actinobacteria	S	HAD-hyrolase-like	-	-	3.1.3.23	ko:K19270	-	-	-	-	ko00000,ko01000	-	-	-	HAD_2
TLS3_k127_2068141_8	1120948.KB903244_gene3086	4.603e-30	124.0	COG0477@1|root,COG2814@2|Bacteria,2GK8C@201174|Actinobacteria,4DZMT@85010|Pseudonocardiales	201174|Actinobacteria	EGP	arabinose efflux permease	-	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1,Sugar_tr
TLS3_k127_2098032_2	1120948.KB903245_gene3578	2.663e-168	535.0	COG0482@1|root,COG0482@2|Bacteria,2GIUQ@201174|Actinobacteria,4DYYX@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
TLS3_k127_2098032_0	1120948.KB903245_gene3579	3.428e-190	602.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,4DY3B@85010|Pseudonocardiales	201174|Actinobacteria	E	Cysteine desulfurase	iscS	GO:0003674,GO:0003824,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0022607,GO:0031071,GO:0031163,GO:0040007,GO:0044085,GO:0044237,GO:0051186,GO:0071840	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
TLS3_k127_2098032_1	1120948.KB903245_gene3580	1.02e-178	563.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4DY2C@85010|Pseudonocardiales	201174|Actinobacteria	C	Electron transfer flavoprotein alpha subunit	etfA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
TLS3_k127_2098032_3	1120948.KB903245_gene3581	2.191e-38	143.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4E0JQ@85010|Pseudonocardiales	201174|Actinobacteria	C	Electron transfer flavoprotein	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
TLS3_k127_2107442_4	1120948.KB903222_gene606	7.283e-32	141.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4DYBT@85010|Pseudonocardiales	201174|Actinobacteria	L	Tyrosine recombinase XerD	xerD	GO:0008150,GO:0040007	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
TLS3_k127_2107442_1	1206733.BAGC01000035_gene3679	9.18e-153	490.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,4FURB@85025|Nocardiaceae	201174|Actinobacteria	E	Belongs to the AlaDH PNT family	ald	GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030312,GO:0036293,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
TLS3_k127_2107442_2	1120948.KB903222_gene607	9.912e-107	350.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,4E0E1@85010|Pseudonocardiales	201174|Actinobacteria	L	pfam nudix	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
TLS3_k127_2107442_0	1120948.KB903222_gene608	1e-323	998.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4DXYQ@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1699	CTP_synth_N,GATase
TLS3_k127_2107442_3	1123023.JIAI01000030_gene4410	1.422e-69	246.0	2D1T0@1|root,32TBA@2|Bacteria,2I8E5@201174|Actinobacteria,4DZE1@85010|Pseudonocardiales	201174|Actinobacteria	S	Copper transport outer membrane protein, MctB	mctB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0008150,GO:0009279,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0044425,GO:0044462,GO:0044464,GO:0046930,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098796	-	-	-	-	-	-	-	-	-	-	MctB
TLS3_k127_2115000_2	1120948.KB903243_gene2603	1.774e-94	321.0	2F02G@1|root,33T66@2|Bacteria,2IGPI@201174|Actinobacteria,4EASH@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2115000_4	1120948.KB903243_gene2361	2.242e-40	169.0	2EI5Z@1|root,33BXC@2|Bacteria	2|Bacteria	S	Polysaccharide lyase	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4,Polysacc_lyase
TLS3_k127_2115000_1	1120948.KB903243_gene2605	1.297e-94	321.0	COG3021@1|root,COG3021@2|Bacteria,2GKXC@201174|Actinobacteria,4E729@85010|Pseudonocardiales	201174|Actinobacteria	S	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_2115000_3	1120948.KB903243_gene2608	1.167e-68	241.0	COG0702@1|root,COG0702@2|Bacteria,2IA0W@201174|Actinobacteria,4E3WX@85010|Pseudonocardiales	201174|Actinobacteria	GM	Domain of unknown function (DUF1990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1990
TLS3_k127_2115000_5	1120948.KB903243_gene2609	5.22e-21	99.0	COG3427@1|root,COG3427@2|Bacteria,2ISBF@201174|Actinobacteria,4EF7I@85010|Pseudonocardiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_2115000_0	1089544.KB912942_gene5597	1.458e-199	630.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,4DXCQ@85010|Pseudonocardiales	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TLS3_k127_2115000_7	1449069.JMLO01000006_gene1110	6.154e-08	56.0	COG3182@1|root,COG3182@2|Bacteria,2GMHE@201174|Actinobacteria,4FWEA@85025|Nocardiaceae	201174|Actinobacteria	S	PepSY-associated TM region	piuB	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
TLS3_k127_2136660_1	1123024.AUII01000013_gene338	2.864e-27	115.0	28ZKW@1|root,2ZMC6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2136660_0	106370.Francci3_3427	7.885e-161	532.0	COG2378@1|root,COG2378@2|Bacteria,2I8XQ@201174|Actinobacteria,4EXB2@85013|Frankiales	201174|Actinobacteria	K	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
TLS3_k127_2136660_2	488538.SAR116_0551	2.572e-13	78.0	2E6ZW@1|root,331IY@2|Bacteria,1NPSI@1224|Proteobacteria,2UKGW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_219219_3	479431.Namu_0488	4.659e-31	126.0	29V0V@1|root,30GDY@2|Bacteria,2IIHM@201174|Actinobacteria,4EXIV@85013|Frankiales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
TLS3_k127_219219_2	1120948.KB903229_gene5233	1.149e-102	337.0	COG0655@1|root,COG0655@2|Bacteria,2GTN2@201174|Actinobacteria,4E2TX@85010|Pseudonocardiales	201174|Actinobacteria	S	NADPH-dependent FMN reductase	wrbA	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red,Flavodoxin_2
TLS3_k127_219219_0	1120948.KB903229_gene5234	1.769e-120	403.0	COG2508@1|root,COG2508@2|Bacteria,2IJ8C@201174|Actinobacteria,4E3DX@85010|Pseudonocardiales	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
TLS3_k127_219219_1	1120948.KB903229_gene5235	1.985e-103	367.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2IB2S@201174|Actinobacteria,4E20B@85010|Pseudonocardiales	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
TLS3_k127_2203151_1	1120948.KB903217_gene1405	1.313e-130	419.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4DY4P@85010|Pseudonocardiales	201174|Actinobacteria	T	Response regulator receiver	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_2203151_0	1120948.KB903217_gene1406	2.882e-142	458.0	COG0248@1|root,COG0248@2|Bacteria,2GMME@201174|Actinobacteria,4DY2Q@85010|Pseudonocardiales	201174|Actinobacteria	FP	PFAM Ppx GppA phosphatase	ppx1	GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
TLS3_k127_2248277_2	1120948.KB903228_gene4789	8.337e-112	371.0	COG0243@1|root,COG0243@2|Bacteria,2GJ7X@201174|Actinobacteria,4E328@85010|Pseudonocardiales	201174|Actinobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	fdhA	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4
TLS3_k127_2248277_1	1120948.KB903228_gene4788	9.13e-188	600.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,4E18B@85010|Pseudonocardiales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
TLS3_k127_2248277_0	1120948.KB903228_gene4787	5.766e-200	636.0	COG1020@1|root,COG1020@2|Bacteria,2GPHZ@201174|Actinobacteria,4E19T@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
TLS3_k127_2248277_3	1068978.AMETH_2922	7.42e-69	243.0	COG3832@1|root,COG3832@2|Bacteria,2IE7C@201174|Actinobacteria,4E3Y2@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_2248277_4	1120934.KB894426_gene3583	6.095e-30	120.0	COG0640@1|root,COG0640@2|Bacteria,2IM1K@201174|Actinobacteria,4E4WI@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
TLS3_k127_2254856_0	1463825.JNXC01000008_gene1256	2.233e-181	596.0	COG0045@1|root,COG1042@1|root,COG1247@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1247@2|Bacteria,2GKN1@201174|Actinobacteria,4DZ1D@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
TLS3_k127_2254856_1	2074.JNYD01000011_gene140	1.903e-12	76.0	COG0589@1|root,COG2905@1|root,COG0589@2|Bacteria,COG2905@2|Bacteria,2I3QN@201174|Actinobacteria,4EF69@85010|Pseudonocardiales	201174|Actinobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS,Usp
TLS3_k127_2257922_2	1120948.KB903217_gene1129	1.01e-56	201.0	COG1251@1|root,COG1251@2|Bacteria,2GJ3U@201174|Actinobacteria,4E84T@85010|Pseudonocardiales	201174|Actinobacteria	C	BFD-like [2Fe-2S] binding domain	nasD	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
TLS3_k127_2257922_4	258533.BN977_03484	4.587e-22	105.0	COG1251@1|root,COG1251@2|Bacteria,2GJ3U@201174|Actinobacteria,2352K@1762|Mycobacteriaceae	201174|Actinobacteria	C	TIGRFAM nitrite reductase NAD(P)H , large subunit	nasD	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
TLS3_k127_2257922_3	1120948.KB903217_gene1130	3.32e-55	202.0	COG3383@1|root,COG3383@2|Bacteria,2INMF@201174|Actinobacteria,4EC4Z@85010|Pseudonocardiales	201174|Actinobacteria	C	formate dehydrogenase (NAD+) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2257922_0	1120948.KB903217_gene1131	0.0	1175.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4DYH3@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	nasC	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
TLS3_k127_2257922_1	1120948.KB903217_gene1134	1.493e-87	293.0	COG2141@1|root,COG2141@2|Bacteria,2GJ66@201174|Actinobacteria,4DYD1@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_2266773_2	1120948.KB903248_gene4285	4.087e-42	157.0	2E49S@1|root,32Z5G@2|Bacteria,2IHN1@201174|Actinobacteria,4E4CA@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3040
TLS3_k127_2266773_1	1120948.KB903248_gene4284	1.501e-82	275.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4E2P4@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
TLS3_k127_2266773_0	1120948.KB903248_gene4283	1.701e-142	460.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4DZ61@85010|Pseudonocardiales	201174|Actinobacteria	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
TLS3_k127_2266773_3	1120948.KB903248_gene4282	1.209e-40	158.0	COG0768@1|root,COG0768@2|Bacteria,2IGM7@201174|Actinobacteria,4EF6I@85010|Pseudonocardiales	201174|Actinobacteria	M	penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2273694_0	1123023.JIAI01000006_gene239	1.07e-143	463.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4DX3U@85010|Pseudonocardiales	201174|Actinobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon
TLS3_k127_2290214_2	2074.JNYD01000008_gene1175	3.46e-85	291.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria,4E0Y5@85010|Pseudonocardiales	201174|Actinobacteria	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_2290214_6	1120948.KB903218_gene2238	3.412e-30	124.0	2EGIC@1|root,33AAH@2|Bacteria,2IFEW@201174|Actinobacteria,4E5M2@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3099)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3099
TLS3_k127_2290214_1	1120948.KB903229_gene5095	5.312e-114	384.0	COG0477@1|root,COG0477@2|Bacteria,2I4K5@201174|Actinobacteria,4E22N@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_2290214_3	1137271.AZUM01000001_gene713	1.538e-40	164.0	2E4RI@1|root,32ZK2@2|Bacteria,2GTNG@201174|Actinobacteria,4E6M9@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2290214_5	211114.JOEF01000023_gene5692	9.485e-32	140.0	COG3631@1|root,COG3631@2|Bacteria,2IHRM@201174|Actinobacteria,4E4ZS@85010|Pseudonocardiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
TLS3_k127_2290214_0	479435.Kfla_1806	1.128e-139	467.0	COG0346@1|root,COG0346@2|Bacteria,2IAYN@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS3_k127_2290214_7	1120948.KB903243_gene2667	9.2e-19	101.0	COG2172@1|root,COG2172@2|Bacteria,2HEYC@201174|Actinobacteria,4ED4V@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
TLS3_k127_2290214_4	1120948.KB903229_gene5024	3.079e-37	151.0	COG1525@1|root,COG1525@2|Bacteria,2I38W@201174|Actinobacteria,4E45P@85010|Pseudonocardiales	201174|Actinobacteria	L	Excalibur calcium-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Excalibur,SNase
TLS3_k127_2291808_2	1120948.KB903218_gene2130	1.322e-143	472.0	COG5438@1|root,COG5438@2|Bacteria,2GKJ4@201174|Actinobacteria,4DY5S@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM YibE F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
TLS3_k127_2291808_0	1120948.KB903240_gene3966	1.599e-254	791.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4DXQJ@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_2291808_3	675635.Psed_5884	4.567e-83	307.0	COG1846@1|root,COG1846@2|Bacteria,2GMDI@201174|Actinobacteria,4EB4P@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2291808_1	1120948.KB903240_gene3965	8.29e-218	702.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4DXBF@85010|Pseudonocardiales	201174|Actinobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TLS3_k127_2291808_5	40571.JOEA01000040_gene4686	7.91e-06	55.0	COG1028@1|root,COG1028@2|Bacteria,2GWHQ@201174|Actinobacteria,4E2SN@85010|Pseudonocardiales	201174|Actinobacteria	IQ	short-chain alcohol	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_2291808_4	1123024.AUII01000004_gene1556	4.665e-21	106.0	COG1403@1|root,COG1403@2|Bacteria,2INVR@201174|Actinobacteria,4EC11@85010|Pseudonocardiales	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
TLS3_k127_2299272_5	1120948.KB903217_gene1207	2.996e-60	211.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria,4DX98@85010|Pseudonocardiales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
TLS3_k127_2299272_7	1120948.KB903217_gene1206	9.674e-31	132.0	COG1828@1|root,COG1828@2|Bacteria,2GQV4@201174|Actinobacteria,4E5FK@85010|Pseudonocardiales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
TLS3_k127_2299272_4	1120948.KB903217_gene1205	2.796e-99	332.0	COG2220@1|root,COG2220@2|Bacteria,2GNHK@201174|Actinobacteria,4E33I@85010|Pseudonocardiales	201174|Actinobacteria	S	Zn-dependent hydrolase of beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
TLS3_k127_2299272_6	1120948.KB903217_gene1203	1.196e-56	208.0	COG3233@1|root,COG3233@2|Bacteria,2HAXX@201174|Actinobacteria,4E3ZQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2334)	-	-	-	ko:K06986	-	-	-	-	ko00000	-	-	-	DUF2334
TLS3_k127_2299272_1	1120948.KB903217_gene1202	1.958e-161	516.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4DZDJ@85010|Pseudonocardiales	201174|Actinobacteria	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
TLS3_k127_2299272_0	1120948.KB903217_gene1201	3.496e-247	777.0	COG0015@1|root,COG0015@2|Bacteria,2GKBR@201174|Actinobacteria,4E0FG@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
TLS3_k127_2299272_3	1120948.KB903227_gene4842	3.135e-124	413.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,2GNAF@201174|Actinobacteria,4DZCW@85010|Pseudonocardiales	201174|Actinobacteria	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,SpoIIE
TLS3_k127_2299272_2	1120934.KB894404_gene648	1.521e-136	454.0	COG4251@1|root,COG4251@2|Bacteria,2GK25@201174|Actinobacteria,4DZCF@85010|Pseudonocardiales	201174|Actinobacteria	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA
TLS3_k127_2299272_8	446462.Amir_5035	4.303e-08	65.0	COG0745@1|root,COG0745@2|Bacteria,2I2VM@201174|Actinobacteria,4E2UJ@85010|Pseudonocardiales	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
TLS3_k127_2299729_0	1120948.KB903245_gene3433	1.939e-138	441.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4DZ1Y@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
TLS3_k127_2299729_1	1123024.AUII01000001_gene2799	9.401e-39	151.0	COG0739@1|root,COG0739@2|Bacteria,2IQ64@201174|Actinobacteria,4E5H3@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_2337205_11	1120948.KB903247_gene4455	1.38e-33	129.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4E6HI@85010|Pseudonocardiales	201174|Actinobacteria	K	Cold shock protein domain	csp	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
TLS3_k127_2337205_3	2074.JNYD01000029_gene7205	4.595e-165	528.0	COG2223@1|root,COG2223@2|Bacteria,2I3SI@201174|Actinobacteria,4E68W@85010|Pseudonocardiales	201174|Actinobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_2337205_7	1380393.JHVP01000007_gene4352	6.074e-88	294.0	2BZ0R@1|root,2Z7U0@2|Bacteria,2GU1J@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Nitrile hydratase alpha	-	-	4.2.1.84	ko:K01721	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R02828,R04020,R05379,R05596,R07780,R07854	RC00483,RC00792,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_alpha
TLS3_k127_2337205_12	2074.JNYD01000003_gene3912	3.868e-33	133.0	2B0GR@1|root,31SU9@2|Bacteria,2GR70@201174|Actinobacteria,4E6VR@85010|Pseudonocardiales	201174|Actinobacteria	S	Nitrile hydratase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	NHase_beta
TLS3_k127_2337205_9	1380393.JHVP01000007_gene4350	4.846e-37	154.0	28I45@1|root,2Z87Q@2|Bacteria,2I95R@201174|Actinobacteria	201174|Actinobacteria	S	NHase catalyzes the hydration of various nitrile compounds to the corresponding amides	nthB	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
TLS3_k127_2337205_2	1120948.KB903248_gene4355	3.358e-166	549.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4DXBU@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
TLS3_k127_2337205_6	1120948.KB903218_gene2052	3.768e-104	351.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
TLS3_k127_2337205_8	1120948.KB903221_gene516	7.843e-61	221.0	2AVNR@1|root,31MFR@2|Bacteria,2HBMC@201174|Actinobacteria	1120948.KB903221_gene516|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2337205_10	1120948.KB903218_gene2120	6.256e-37	156.0	2EPBK@1|root,33GYC@2|Bacteria,2IHZ9@201174|Actinobacteria,4E53J@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2337205_1	1120948.KB903229_gene5040	7.157e-183	576.0	COG0332@1|root,COG0332@2|Bacteria,2I9C8@201174|Actinobacteria,4E7B4@85010|Pseudonocardiales	201174|Actinobacteria	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	-	-	2.3.1.180	ko:K00648,ko:K22317	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
TLS3_k127_2337205_4	1120948.KB903229_gene5041	9.432e-160	517.0	COG0596@1|root,COG0596@2|Bacteria,2I99I@201174|Actinobacteria,4E4K3@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
TLS3_k127_2337205_0	1120948.KB903229_gene5042	2.494e-261	830.0	COG0318@1|root,COG0318@2|Bacteria,2GJR0@201174|Actinobacteria,4DYEX@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	6.1.3.1	ko:K22319	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,Abhydrolase_1
TLS3_k127_2337205_5	1120948.KB903229_gene5043	8.919e-108	379.0	COG0451@1|root,COG0451@2|Bacteria,2GMHH@201174|Actinobacteria,4E213@85010|Pseudonocardiales	201174|Actinobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	GO:0000166,GO:0003674,GO:0003824,GO:0003854,GO:0004769,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016020,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016853,GO:0016860,GO:0016863,GO:0030283,GO:0033764,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901360,GO:1901363	1.1.1.145,1.1.1.412,5.3.3.1	ko:K16045,ko:K22320	ko00984,ko01120,map00984,map01120	-	R09920	RC00146	ko00000,ko00001,ko01000	-	-	-	3Beta_HSD,Epimerase
TLS3_k127_2346073_2	1120948.KB903228_gene4794	2.972e-74	253.0	COG1921@1|root,COG1921@2|Bacteria,2HFGK@201174|Actinobacteria,4DY7G@85010|Pseudonocardiales	201174|Actinobacteria	E	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
TLS3_k127_2346073_0	1120948.KB903228_gene4795	1.338e-263	826.0	COG3276@1|root,COG3276@2|Bacteria,2GKF9@201174|Actinobacteria,4DY2E@85010|Pseudonocardiales	201174|Actinobacteria	J	elongation factor SelB, winged helix	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
TLS3_k127_2346073_1	1120948.KB903229_gene5256	3.957e-86	297.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4DX5K@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
TLS3_k127_2356244_7	37919.EP51_29380	6.448e-34	138.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,4FYMD@85025|Nocardiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
TLS3_k127_2356244_6	1120934.KB894414_gene3813	3.574e-35	142.0	COG1576@1|root,COG1576@2|Bacteria,2IG2P@201174|Actinobacteria,4E64S@85010|Pseudonocardiales	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
TLS3_k127_2356244_4	1157637.KB892111_gene4201	1.766e-71	266.0	COG2267@1|root,COG2267@2|Bacteria,2GU81@201174|Actinobacteria	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2356244_3	1120948.KB903229_gene5197	5.18e-141	456.0	COG1540@1|root,COG1540@2|Bacteria,2GJA1@201174|Actinobacteria,4E27P@85010|Pseudonocardiales	201174|Actinobacteria	S	LamB/YcsF family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
TLS3_k127_2356244_0	1120948.KB903229_gene5198	4.895e-207	659.0	COG0439@1|root,COG0439@2|Bacteria,2I2S0@201174|Actinobacteria,4DXG8@85010|Pseudonocardiales	201174|Actinobacteria	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
TLS3_k127_2356244_8	1120948.KB903229_gene5199	8.52e-30	124.0	COG0511@1|root,COG0511@2|Bacteria,2IR3V@201174|Actinobacteria,4E75N@85010|Pseudonocardiales	201174|Actinobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
TLS3_k127_2356244_2	1120948.KB903229_gene5200	2.012e-161	528.0	COG1984@1|root,COG1984@2|Bacteria,2GITH@201174|Actinobacteria,4DYK9@85010|Pseudonocardiales	201174|Actinobacteria	E	Allophanate hydrolase subunit 2	-	-	-	-	-	-	-	-	-	-	-	-	CT_A_B
TLS3_k127_2356244_1	1120948.KB903229_gene5201	8.576e-163	516.0	COG2049@1|root,COG2049@2|Bacteria,2I9QZ@201174|Actinobacteria,4E1DC@85010|Pseudonocardiales	201174|Actinobacteria	E	Allophanate hydrolase subunit 1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	CT_C_D
TLS3_k127_2356244_5	1380356.JNIK01000021_gene4568	1.585e-51	190.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria,4ESW7@85013|Frankiales	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
TLS3_k127_2356824_0	1123024.AUII01000026_gene2543	4.4e-289	895.0	COG0845@1|root,COG4770@1|root,COG4799@1|root,COG0845@2|Bacteria,COG4770@2|Bacteria,COG4799@2|Bacteria,2GIZP@201174|Actinobacteria,4DZJ9@85010|Pseudonocardiales	201174|Actinobacteria	I	Acetyl propionyl-CoA carboxylase, alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	ACC_central,Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
TLS3_k127_2356824_1	675635.Psed_5169	1.313e-114	377.0	COG1024@1|root,COG1024@2|Bacteria,2HEIS@201174|Actinobacteria,4DZPT@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
TLS3_k127_2356824_2	1120948.KB903240_gene4130	9.65e-90	300.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,4E5MV@85010|Pseudonocardiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,HxlR,SCP2
TLS3_k127_2356824_3	1120948.KB903240_gene4131	2.233e-67	235.0	COG0346@1|root,COG0346@2|Bacteria,2GQZ9@201174|Actinobacteria,4E3T6@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_2356824_4	1120948.KB903240_gene4132	1.035e-27	112.0	COG1024@1|root,COG1024@2|Bacteria,2HHR6@201174|Actinobacteria,4DXU9@85010|Pseudonocardiales	201174|Actinobacteria	I	enoyl-CoA hydratase	Echdc	-	-	-	-	-	-	-	-	-	-	-	ECH_1
TLS3_k127_2365322_1	1120948.KB903246_gene3216	4.483e-38	147.0	COG4270@1|root,COG4270@2|Bacteria,2IQJ5@201174|Actinobacteria,4E5T6@85010|Pseudonocardiales	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
TLS3_k127_2365322_0	1120948.KB903246_gene3215	6.371e-253	787.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4DY6F@85010|Pseudonocardiales	201174|Actinobacteria	E	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
TLS3_k127_2370600_0	284031.JNXD01000009_gene2167	7.595e-149	477.0	COG4427@1|root,COG4427@2|Bacteria,2HVQW@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
TLS3_k127_2370600_1	1123024.AUII01000028_gene2480	7.666e-87	296.0	28I45@1|root,2Z87Q@2|Bacteria,2I95R@201174|Actinobacteria	201174|Actinobacteria	S	NHase catalyzes the hydration of various nitrile compounds to the corresponding amides	-	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
TLS3_k127_2370600_2	1157637.KB892121_gene272	4.264e-81	286.0	2BZ0R@1|root,2Z7U0@2|Bacteria,2GU1J@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Nitrile hydratase alpha	-	-	4.2.1.84	ko:K01721	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R02828,R04020,R05379,R05596,R07780,R07854	RC00483,RC00792,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_alpha
TLS3_k127_2370600_3	653045.Strvi_5571	6.516e-34	147.0	2E0AM@1|root,32VXZ@2|Bacteria,2IMA6@201174|Actinobacteria	201174|Actinobacteria	S	Nitrile hydratase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	NHase_beta
TLS3_k127_238128_1	1120948.KB903245_gene3559	3.325e-137	463.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4DXVY@85010|Pseudonocardiales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
TLS3_k127_238128_0	1120948.KB903245_gene3560	8.18e-240	759.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4DXTM@85010|Pseudonocardiales	201174|Actinobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
TLS3_k127_238128_5	1120948.KB903245_gene3561	7.926e-40	156.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4E4D6@85010|Pseudonocardiales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
TLS3_k127_238128_4	1120948.KB903245_gene3562	9.46e-101	335.0	COG0317@1|root,COG0317@2|Bacteria,2GNRE@201174|Actinobacteria,4E103@85010|Pseudonocardiales	201174|Actinobacteria	KT	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT
TLS3_k127_238128_2	1120948.KB903245_gene3563	4.805e-136	437.0	COG3246@1|root,COG3246@2|Bacteria,2GMMZ@201174|Actinobacteria,4E42A@85010|Pseudonocardiales	201174|Actinobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
TLS3_k127_238128_3	1120948.KB903245_gene3564	1.409e-112	366.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4E0P6@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
TLS3_k127_2390943_0	1120948.KB903240_gene3863	2.034e-283	882.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4E0HF@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	gbsA	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_2390943_2	1123024.AUII01000027_gene2642	3.421e-52	193.0	COG2264@1|root,COG2264@2|Bacteria,2IIDT@201174|Actinobacteria,4EEW8@85010|Pseudonocardiales	201174|Actinobacteria	J	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
TLS3_k127_2390943_1	1120948.KB903217_gene1262	3.841e-125	406.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria,4DZJW@85010|Pseudonocardiales	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
TLS3_k127_2434524_2	1120948.KB903224_gene348	1.637e-88	295.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4E0VT@85010|Pseudonocardiales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0035601,GO:0036211,GO:0040007,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0098732,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
TLS3_k127_2434524_0	2074.JNYD01000018_gene2767	1.353e-115	391.0	COG0265@1|root,COG0265@2|Bacteria,2GNZT@201174|Actinobacteria,4DZ7M@85010|Pseudonocardiales	201174|Actinobacteria	O	C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
TLS3_k127_2434524_1	1120948.KB903224_gene350	1.381e-93	313.0	COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria,4DYMA@85010|Pseudonocardiales	201174|Actinobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
TLS3_k127_2455498_0	2074.JNYD01000017_gene4301	7.868e-174	560.0	COG0620@1|root,COG0620@2|Bacteria,2GIXA@201174|Actinobacteria,4E2EF@85010|Pseudonocardiales	201174|Actinobacteria	E	Cobalamin-independent synthase, Catalytic domain	metE	-	2.1.1.14,4.4.1.23	ko:K00549,ko:K22363	ko00270,ko00450,ko00625,ko01100,ko01110,ko01230,map00270,map00450,map00625,map01100,map01110,map01230	M00017	R04405,R09365,R11897,R11899	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
TLS3_k127_2455498_1	1463879.JOHP01000045_gene274	2.084e-75	257.0	COG0604@1|root,COG0604@2|Bacteria,2GMA2@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
TLS3_k127_2459443_0	1120948.KB903243_gene2463	1.162e-217	690.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DXGB@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpA3	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
TLS3_k127_2460040_3	1089453.GOSPT_125_00420	0.0004688	46.0	2C2EQ@1|root,34BST@2|Bacteria,2H188@201174|Actinobacteria,4GF67@85026|Gordoniaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2460040_0	675635.Psed_3763	3.921e-93	317.0	COG4221@1|root,COG4221@2|Bacteria,2GRRV@201174|Actinobacteria,4DX5G@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_2460040_1	1123023.JIAI01000012_gene9047	2.558e-74	259.0	COG2197@1|root,COG2197@2|Bacteria,2INB6@201174|Actinobacteria,4E4JS@85010|Pseudonocardiales	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_2460040_2	1297742.A176_03086	9.478e-31	135.0	COG2518@1|root,COG2518@2|Bacteria,1QXUI@1224|Proteobacteria,43C72@68525|delta/epsilon subdivisions,2X7HB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Specifically methylates the guanosine in position 1516 of 16S rRNA	-	-	-	-	-	-	-	-	-	-	-	-	SAM_MT
TLS3_k127_2476200_2	1120948.KB903217_gene1016	6.438e-10	64.0	2CFU2@1|root,33SRM@2|Bacteria,2INCI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2476200_1	1120948.KB903217_gene1015	5.424e-245	767.0	COG5650@1|root,COG5650@2|Bacteria,2GJYA@201174|Actinobacteria,4DZD8@85010|Pseudonocardiales	201174|Actinobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	GT87
TLS3_k127_2476200_0	1120948.KB903217_gene1014	1.03e-321	1004.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4DZ3P@85010|Pseudonocardiales	201174|Actinobacteria	M	Membrane carboxypeptidase (Penicillin-binding protein)	pbp1A	GO:0001666,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0008144,GO:0008150,GO:0008658,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0033218,GO:0033293,GO:0033554,GO:0036094,GO:0036293,GO:0036294,GO:0042221,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0050896,GO:0051716,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0097159,GO:1901363,GO:1901681	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
TLS3_k127_247700_0	1120948.KB903225_gene5567	1.056e-166	533.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4E1GX@85010|Pseudonocardiales	201174|Actinobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
TLS3_k127_247700_4	1120948.KB903225_gene5569	2.853e-57	202.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4E5Z7@85010|Pseudonocardiales	201174|Actinobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
TLS3_k127_247700_2	1120948.KB903225_gene5570	6.751e-92	321.0	COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria,4E0U1@85010|Pseudonocardiales	201174|Actinobacteria	F	PFAM Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
TLS3_k127_247700_1	1120948.KB903225_gene5571	1.596e-117	402.0	COG2141@1|root,COG2141@2|Bacteria,2GJ3B@201174|Actinobacteria,4E2IM@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_247700_3	1120948.KB903225_gene5573	3.008e-61	223.0	COG3871@1|root,COG3871@2|Bacteria,2IKYK@201174|Actinobacteria,4E4FS@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0030312,GO:0031406,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
TLS3_k127_247700_5	405948.SACE_1266	1.254e-18	91.0	COG0019@1|root,COG0019@2|Bacteria,2HIAB@201174|Actinobacteria,4DXEU@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the Orn Lys Arg decarboxylase class-II family	-	-	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS3_k127_2488628_2	1120948.KB903217_gene1469	2.389e-51	184.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4DY0P@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
TLS3_k127_2488628_1	1120948.KB903217_gene1470	1.078e-116	384.0	COG2962@1|root,COG2962@2|Bacteria,2GKCP@201174|Actinobacteria,4DXBB@85010|Pseudonocardiales	201174|Actinobacteria	S	EamA-like transporter family	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
TLS3_k127_2488628_0	1123024.AUII01000031_gene517	1.241e-172	552.0	COG1237@1|root,COG1237@2|Bacteria,2I8H7@201174|Actinobacteria,4DZYW@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
TLS3_k127_2488628_3	1120948.KB903217_gene1472	2.716e-27	111.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria,4DXJZ@85010|Pseudonocardiales	201174|Actinobacteria	C	ferredoxin oxidoreductase, beta subunit	korB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
TLS3_k127_25054_1	208444.JNYY01000010_gene2635	2.873e-11	65.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4E0RB@85010|Pseudonocardiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_25054_2	1463903.JOIZ01000007_gene4066	4.685e-05	54.0	2E5AY@1|root,33032@2|Bacteria,2GKU5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_25054_0	266940.Krad_3094	5.064e-27	118.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Uncharacterised ACR, COG1259	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
TLS3_k127_2509891_4	983917.RGE_06520	0.0005168	51.0	COG0607@1|root,COG0607@2|Bacteria,1RHQZ@1224|Proteobacteria,2VT6V@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS3_k127_2509891_1	1120948.KB903227_gene4865	3.207e-155	501.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4E1U3@85010|Pseudonocardiales	201174|Actinobacteria	S	Sulfatase-modifying factor enzyme 1	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005509,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0120147,GO:1901564,GO:1903135	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
TLS3_k127_2509891_0	1120948.KB903227_gene4864	0.0	1303.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4DXAF@85010|Pseudonocardiales	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
TLS3_k127_2509891_2	1120948.KB903227_gene4866	1.882e-134	435.0	COG0583@1|root,COG0583@2|Bacteria,2GM99@201174|Actinobacteria,4DYY1@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS3_k127_2509891_3	1120948.KB903229_gene5043	1.022e-97	321.0	COG0451@1|root,COG0451@2|Bacteria,2GMHH@201174|Actinobacteria,4E213@85010|Pseudonocardiales	201174|Actinobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	GO:0000166,GO:0003674,GO:0003824,GO:0003854,GO:0004769,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016020,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016853,GO:0016860,GO:0016863,GO:0030283,GO:0033764,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901360,GO:1901363	1.1.1.145,1.1.1.412,5.3.3.1	ko:K16045,ko:K22320	ko00984,ko01120,map00984,map01120	-	R09920	RC00146	ko00000,ko00001,ko01000	-	-	-	3Beta_HSD,Epimerase
TLS3_k127_2517625_0	1120948.KB903218_gene2173	2.913e-65	225.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4DZGI@85010|Pseudonocardiales	201174|Actinobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
TLS3_k127_2517625_2	469383.Cwoe_2996	1.321e-41	169.0	COG0596@1|root,COG0596@2|Bacteria,2I32Y@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
TLS3_k127_2517625_1	1120948.KB903218_gene2174	3.064e-63	220.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4E2QQ@85010|Pseudonocardiales	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
TLS3_k127_2543190_6	1283283.ATXA01000001_gene1214	1.071e-16	81.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4EUDP@85013|Frankiales	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
TLS3_k127_2543190_3	1120948.KB903245_gene3594	1.604e-102	344.0	COG2227@1|root,COG2227@2|Bacteria,2GMMX@201174|Actinobacteria,4DXPQ@85010|Pseudonocardiales	201174|Actinobacteria	H	PFAM Methyltransferase domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
TLS3_k127_2543190_7	1121020.JIAG01000004_gene2175	1.271e-06	62.0	COG3742@1|root,COG3742@2|Bacteria,2IS39@201174|Actinobacteria,1WBKV@1268|Micrococcaceae	201174|Actinobacteria	S	PIN domain	-	-	-	ko:K19686	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
TLS3_k127_2543190_0	1120948.KB903245_gene3596	1.348e-269	837.0	COG1543@1|root,COG1543@2|Bacteria,2GKTI@201174|Actinobacteria,4DZYG@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
TLS3_k127_2543190_1	1120948.KB903245_gene3597	3.107e-188	596.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4DZ70@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl transferases group 1	-	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.11	ko:K16150	ko00500,ko01100,map00500,map01100	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_2543190_2	1120948.KB903245_gene3598	2.027e-118	384.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4DZBZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
TLS3_k127_2543190_4	1120948.KB903244_gene3021	5.176e-47	177.0	2BDBD@1|root,32702@2|Bacteria,2HSCM@201174|Actinobacteria,4ED9K@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2543190_5	1120948.KB903244_gene3022	4.707e-35	135.0	COG1734@1|root,COG1734@2|Bacteria,2HPB5@201174|Actinobacteria,4E7XD@85010|Pseudonocardiales	201174|Actinobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
TLS3_k127_2564494_5	1449353.JQMQ01000005_gene5408	1.592e-48	194.0	COG0500@1|root,COG2226@2|Bacteria,2HWAV@201174|Actinobacteria,2NHWR@228398|Streptacidiphilus	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_2564494_1	1120948.KB903229_gene5106	1.092e-151	501.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4DY7E@85010|Pseudonocardiales	201174|Actinobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
TLS3_k127_2564494_6	1120948.KB903244_gene3008	1.708e-47	185.0	COG1266@1|root,COG1266@2|Bacteria,2GKRA@201174|Actinobacteria,4E5VT@85010|Pseudonocardiales	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
TLS3_k127_2564494_0	1120948.KB903244_gene3007	9.65e-172	584.0	COG4425@1|root,COG4425@2|Bacteria,2GKB5@201174|Actinobacteria,4DXFU@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta-hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_9,Abhydrolase_9_N
TLS3_k127_2564494_3	2074.JNYD01000041_gene3367	4.15e-89	332.0	COG0154@1|root,COG0154@2|Bacteria,2I9DH@201174|Actinobacteria,4E9C2@85010|Pseudonocardiales	201174|Actinobacteria	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
TLS3_k127_2564494_2	1449976.KALB_6166	3.697e-95	316.0	COG0009@1|root,COG0009@2|Bacteria,2GNEW@201174|Actinobacteria,4DX96@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the SUA5 family	-	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
TLS3_k127_2564494_7	1133849.O3I_022865	8.543e-06	58.0	COG1366@1|root,COG1366@2|Bacteria,2HP99@201174|Actinobacteria,4G2HI@85025|Nocardiaceae	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
TLS3_k127_2564494_4	1120948.KB903240_gene3841	1.231e-66	235.0	COG0730@1|root,COG0730@2|Bacteria,2II68@201174|Actinobacteria	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_2564494_9	396014.BF93_04850	0.0002242	50.0	2E9A0@1|root,33HX8@2|Bacteria,2I25T@201174|Actinobacteria,4FDZZ@85020|Dermabacteraceae	201174|Actinobacteria	S	Domain of unknown function (DUF4333)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4333
TLS3_k127_2564494_8	367299.JOEE01000012_gene3239	0.000176	44.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria,4FF2V@85021|Intrasporangiaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_2571454_0	675635.Psed_3602	4.085e-116	395.0	COG0480@1|root,COG0480@2|Bacteria,2GKRU@201174|Actinobacteria,4DYQ5@85010|Pseudonocardiales	201174|Actinobacteria	J	elongation factor G domain IV	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
TLS3_k127_2574526_1	1209984.BN978_02847	4.892e-16	80.0	2EHCF@1|root,33B4A@2|Bacteria,2GSFV@201174|Actinobacteria,23B84@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF4244)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4244
TLS3_k127_2574526_3	1114959.SZMC14600_12735	5.975e-12	75.0	2EGB2@1|root,33A2X@2|Bacteria,2HKYY@201174|Actinobacteria,4E6PN@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TadE
TLS3_k127_2574526_2	675635.Psed_0399	7.044e-16	86.0	2DRBM@1|root,33B4F@2|Bacteria,2GXTD@201174|Actinobacteria,4E6G8@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM helicase secretion neighborhood TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Tad
TLS3_k127_2574526_0	1120948.KB903229_gene5017	9.829e-115	372.0	2EJSR@1|root,33DHD@2|Bacteria,2GMHI@201174|Actinobacteria,4E3BB@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Bifunctional DNA primase polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Prim-Pol
TLS3_k127_2612185_5	1120948.KB903231_gene4708	1.693e-07	59.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4DX5P@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Diacylglycerol kinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
TLS3_k127_2612185_0	1120948.KB903231_gene4706	2.698e-95	317.0	COG0406@1|root,COG0406@2|Bacteria,2GNRS@201174|Actinobacteria,4E2TN@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Phosphoglycerate mutase family	gpm2	GO:0003674,GO:0003824,GO:0003993,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0042802,GO:0042803,GO:0044237,GO:0046983	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
TLS3_k127_2612185_1	2074.JNYD01000031_gene6531	1.49e-72	248.0	293MU@1|root,2ZR3M@2|Bacteria,2IFCB@201174|Actinobacteria,4E2Z8@85010|Pseudonocardiales	201174|Actinobacteria	S	Nickel-containing superoxide dismutase	sodN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
TLS3_k127_2612185_3	1050202.KB913024_gene2659	2.634e-31	127.0	COG2932@1|root,COG2932@2|Bacteria,2I2AM@201174|Actinobacteria,409FS@622450|Actinopolysporales	201174|Actinobacteria	K	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
TLS3_k127_2612185_2	1120948.KB903245_gene3722	4.542e-51	183.0	COG1898@1|root,COG1898@2|Bacteria,2GMW4@201174|Actinobacteria,4E0M8@85010|Pseudonocardiales	201174|Actinobacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase	rmlC	-	5.1.3.13	ko:K01790,ko:K16438	ko00404,ko00521,ko00523,ko01055,ko01130,map00404,map00521,map00523,map01055,map01130	M00793,M00798,M00799,M00800	R06433,R06514,R06628,R08934,R11046,R11138	RC01518,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
TLS3_k127_2626442_0	1120948.KB903229_gene5054	4.206e-183	586.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4DX9Q@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA RNA helicase, superfamily II	rhlE1	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
TLS3_k127_2626442_1	1306174.JODP01000006_gene3777	2.334e-29	124.0	COG4282@1|root,COG4282@2|Bacteria	2|Bacteria	G	regulation of fungal-type cell wall biogenesis	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	SMI1_KNR4
TLS3_k127_2626442_2	1120948.KB903229_gene5141	7.631e-29	118.0	28PSZ@1|root,2ZCEC@2|Bacteria,2GMRM@201174|Actinobacteria,4DZ6M@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2646559_9	710111.FraQA3DRAFT_4480	4.577e-31	144.0	2CC51@1|root,2Z7IU@2|Bacteria,2GM14@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2397
TLS3_k127_2646559_0	1120948.KB903217_gene1083	0.0	1725.0	COG0419@1|root,COG1196@1|root,COG0419@2|Bacteria,COG1196@2|Bacteria,2GK6F@201174|Actinobacteria,4DYJA@85010|Pseudonocardiales	201174|Actinobacteria	D	Putative exonuclease SbcCD, C subunit	-	-	-	-	-	-	-	-	-	-	-	-	SbcCD_C
TLS3_k127_2646559_8	1068980.ARVW01000001_gene4925	4.941e-63	231.0	COG3178@1|root,COG3178@2|Bacteria,2GNRB@201174|Actinobacteria,4E2VN@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
TLS3_k127_2646559_4	1120948.KB903217_gene1082	2.588e-100	338.0	COG3022@1|root,COG3022@2|Bacteria,2GJPM@201174|Actinobacteria,4DXMF@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the UPF0246 family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
TLS3_k127_2646559_2	1120948.KB903217_gene1081	6.153e-121	398.0	COG1680@1|root,COG1680@2|Bacteria,2GNVX@201174|Actinobacteria,4DY2B@85010|Pseudonocardiales	201174|Actinobacteria	V	Beta-lactamase class C	bla	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_2646559_6	1120948.KB903217_gene1080	5.588e-79	274.0	COG2367@1|root,COG2367@2|Bacteria,2GKPU@201174|Actinobacteria,4E4MS@85010|Pseudonocardiales	201174|Actinobacteria	V	Beta-lactamase	lppW	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
TLS3_k127_2646559_7	65497.JODV01000006_gene814	3.99e-71	252.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria,4DXH4@85010|Pseudonocardiales	201174|Actinobacteria	M	Mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
TLS3_k127_2646559_1	1120948.KB903217_gene1079	1.899e-208	657.0	COG0530@1|root,COG0530@2|Bacteria,2GP6H@201174|Actinobacteria,4E18G@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM sodium calcium exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
TLS3_k127_2646559_3	1120948.KB903217_gene1078	8.777e-108	377.0	2B0GJ@1|root,31SU3@2|Bacteria,2INYH@201174|Actinobacteria,4EAVU@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2646559_5	1146883.BLASA_2244	3.595e-94	311.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4ES4E@85013|Frankiales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
TLS3_k127_2647432_4	675635.Psed_6293	2.027e-20	91.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4E9VP@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	caiA	-	1.3.8.13	ko:K08297,ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_2647432_2	1120948.KB903244_gene2748	8.203e-70	243.0	COG1056@1|root,COG1056@2|Bacteria,2GRY1@201174|Actinobacteria,4EB8S@85010|Pseudonocardiales	201174|Actinobacteria	H	Cytidylyltransferase-like	-	-	2.7.7.1	ko:K00952	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
TLS3_k127_2647432_1	1120948.KB903244_gene2747	1.365e-197	636.0	COG3635@1|root,COG3635@2|Bacteria,2IQCA@201174|Actinobacteria,4E72B@85010|Pseudonocardiales	201174|Actinobacteria	G	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
TLS3_k127_2647432_0	882083.SacmaDRAFT_5478	4.256e-210	658.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4DZT1@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_2647432_3	1120948.KB903240_gene4046	3.027e-52	194.0	COG1795@1|root,COG1795@2|Bacteria,2IGCK@201174|Actinobacteria,4E7F8@85010|Pseudonocardiales	201174|Actinobacteria	S	Formaldehyde-activating enzyme (Fae)	-	-	4.2.1.147	ko:K10713	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R08058	RC01583,RC01795	ko00000,ko00001,ko01000	-	-	-	Fae
TLS3_k127_2647432_5	1123320.KB889687_gene931	8.836e-16	79.0	COG2084@1|root,COG2084@2|Bacteria,2GNHV@201174|Actinobacteria	201174|Actinobacteria	I	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_2
TLS3_k127_2650765_3	1120948.KB903245_gene3716	3.492e-76	257.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4DZK6@85010|Pseudonocardiales	201174|Actinobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
TLS3_k127_2650765_2	1120948.KB903245_gene3689	1.252e-90	312.0	COG0523@1|root,COG0523@2|Bacteria,2GKDR@201174|Actinobacteria,4E168@85010|Pseudonocardiales	201174|Actinobacteria	S	Cobalamin synthesis protein cobW C-terminal domain	cobW	-	-	ko:K02234	-	-	-	-	ko00000,ko00001	-	-	-	CobW_C,cobW
TLS3_k127_2650765_8	1120948.KB903245_gene3715	1.161e-24	114.0	2E460@1|root,32Z20@2|Bacteria,2GQGS@201174|Actinobacteria,4E6KG@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2650765_0	1120948.KB903245_gene3714	0.0	2046.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4DYC3@85010|Pseudonocardiales	201174|Actinobacteria	C	Dehydrogenase E1 component	kgd	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
TLS3_k127_2650765_6	526225.Gobs_3942	1.27e-41	163.0	COG5662@1|root,COG5662@2|Bacteria,2INVC@201174|Actinobacteria	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
TLS3_k127_2650765_5	479435.Kfla_3918	5.288e-55	205.0	COG1595@1|root,COG1595@2|Bacteria,2IMV5@201174|Actinobacteria,4DWQD@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS3_k127_2650765_4	1449068.JMLQ01000002_gene2888	6.369e-73	256.0	2DJRI@1|root,3072H@2|Bacteria,2IGMC@201174|Actinobacteria,4G20N@85025|Nocardiaceae	201174|Actinobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
TLS3_k127_2650765_7	1380356.JNIK01000016_gene3716	1.652e-36	151.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria,4ET12@85013|Frankiales	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
TLS3_k127_2650765_1	1120948.KB903245_gene3712	2.253e-137	442.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4DXBD@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS3_k127_265451_0	1120948.KB903219_gene798	0.0	1040.0	COG2759@1|root,COG2759@2|Bacteria,2GT0X@201174|Actinobacteria,4DXJB@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
TLS3_k127_265451_3	1120948.KB903219_gene799	1.373e-47	190.0	COG3404@1|root,COG3404@2|Bacteria,2HSFU@201174|Actinobacteria,4EDK3@85010|Pseudonocardiales	201174|Actinobacteria	E	Formiminotransferase-cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
TLS3_k127_265451_2	1120948.KB903219_gene800	2.518e-79	280.0	COG4448@1|root,COG4448@2|Bacteria,2GJA7@201174|Actinobacteria,4DYR1@85010|Pseudonocardiales	201174|Actinobacteria	E	L-asparaginase II	ansA	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
TLS3_k127_265451_4	1120948.KB903219_gene801	9.888e-39	152.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
TLS3_k127_265451_1	1120948.KB903219_gene803	1.942e-145	471.0	COG0079@1|root,COG0079@2|Bacteria,2I2ND@201174|Actinobacteria,4DYDQ@85010|Pseudonocardiales	201174|Actinobacteria	E	Aminotransferase class I and II	cobC	GO:0008150,GO:0040007	2.6.1.9,4.1.1.81	ko:K00817,ko:K04720	ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243,R06530	RC00006,RC00517,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,CbiG_C
TLS3_k127_265451_5	1120948.KB903219_gene804	1.05e-38	162.0	COG0778@1|root,COG2038@1|root,COG0778@2|Bacteria,COG2038@2|Bacteria,2GJ16@201174|Actinobacteria,4E2AX@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT,Nitroreductase
TLS3_k127_2662267_3	1120948.KB903240_gene3828	2.083e-72	258.0	COG1714@1|root,COG1714@2|Bacteria,2H4MP@201174|Actinobacteria,4E2SC@85010|Pseudonocardiales	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
TLS3_k127_2662267_2	1120948.KB903240_gene3829	5.805e-134	436.0	COG1300@1|root,COG1300@2|Bacteria,2GJTG@201174|Actinobacteria,4E0T2@85010|Pseudonocardiales	201174|Actinobacteria	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
TLS3_k127_2662267_5	1120948.KB903240_gene3822	9.465e-62	234.0	COG2207@1|root,COG2207@2|Bacteria,2IFDE@201174|Actinobacteria,4E2S3@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_2662267_4	1240349.ANGC01000003_gene2104	2.053e-66	233.0	COG0346@1|root,COG0346@2|Bacteria,2IG0S@201174|Actinobacteria,4G0ZN@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_2662267_1	1120948.KB903240_gene3830	1.073e-156	507.0	COG1721@1|root,COG1721@2|Bacteria,2GK9A@201174|Actinobacteria,4DXK9@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF58
TLS3_k127_2662267_0	1120948.KB903240_gene3831	4.12e-161	513.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4DYDC@85010|Pseudonocardiales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TLS3_k127_2662267_6	935839.JAGJ01000002_gene799	5.256e-17	84.0	29B69@1|root,2ZY4N@2|Bacteria,2GKQW@201174|Actinobacteria,4F4HW@85017|Promicromonosporaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4350)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF4350
TLS3_k127_2662567_1	1120948.KB903229_gene5153	1.7e-148	480.0	COG0119@1|root,COG0119@2|Bacteria,2GKTP@201174|Actinobacteria,4E04I@85010|Pseudonocardiales	201174|Actinobacteria	E	HMGL-like	-	-	4.1.3.4,4.1.3.46	ko:K01640,ko:K18314	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090,R10674	RC00502,RC00503,RC01118,RC01205,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
TLS3_k127_2662567_2	208444.JNYY01000007_gene8051	1.512e-55	203.0	COG1522@1|root,COG1522@2|Bacteria,2H7NM@201174|Actinobacteria,4E53Z@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
TLS3_k127_2662567_0	1120948.KB903245_gene3709	9.948e-171	543.0	COG2609@1|root,COG2609@2|Bacteria,2GND8@201174|Actinobacteria,4DYXC@85010|Pseudonocardiales	201174|Actinobacteria	C	Transketolase, thiamine diphosphate binding domain	aceE_1	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_C,Transketolase_N
TLS3_k127_266564_8	287986.DV20_24465	1.045e-06	55.0	COG5651@1|root,COG5651@2|Bacteria,2IGJR@201174|Actinobacteria,4EAQY@85010|Pseudonocardiales	201174|Actinobacteria	N	PPE family	-	-	-	-	-	-	-	-	-	-	-	-	WXG100
TLS3_k127_266564_7	345341.KUTG_06096	1.341e-19	99.0	2DV49@1|root,33TZG@2|Bacteria,2IG7I@201174|Actinobacteria,4DX6G@85010|Pseudonocardiales	201174|Actinobacteria	S	EspG family	-	-	-	-	-	-	-	-	-	-	-	-	ESX-1_EspG
TLS3_k127_266564_6	1146883.BLASA_4821	2.188e-64	233.0	COG2304@1|root,COG2304@2|Bacteria,2I959@201174|Actinobacteria	201174|Actinobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_CoxE
TLS3_k127_266564_5	526225.Gobs_4949	1.702e-110	366.0	COG0714@1|root,COG0714@2|Bacteria,2GMBP@201174|Actinobacteria,4ERVI@85013|Frankiales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
TLS3_k127_266564_2	1123023.JIAI01000017_gene3637	8.124e-197	618.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4E87G@85010|Pseudonocardiales	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_266564_0	1120948.KB903229_gene5407	5.75e-229	717.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4DXHD@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
TLS3_k127_266564_4	1120948.KB903229_gene5408	8.392e-160	509.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4DXWI@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
TLS3_k127_266564_3	1146883.BLASA_3405	1.378e-174	557.0	COG2031@1|root,COG2031@2|Bacteria,2HVTQ@201174|Actinobacteria	201174|Actinobacteria	I	Short chain fatty	atoE	-	-	ko:K02106	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.73.1	-	-	SCFA_trans
TLS3_k127_266564_1	1120948.KB903229_gene5410	9.121e-207	659.0	COG2114@1|root,COG2114@2|Bacteria,2GJRI@201174|Actinobacteria,4DZBF@85010|Pseudonocardiales	201174|Actinobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
TLS3_k127_2669448_2	479433.Caci_0163	9.431e-83	277.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
TLS3_k127_2669448_0	1429046.RR21198_5874	5.832e-219	703.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4FWEF@85025|Nocardiaceae	201174|Actinobacteria	I	carboxylase	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
TLS3_k127_2669448_1	1429046.RR21198_5873	3.877e-167	559.0	COG3185@1|root,COG3185@2|Bacteria,2GJNC@201174|Actinobacteria,4FVPF@85025|Nocardiaceae	201174|Actinobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
TLS3_k127_2682365_0	1120948.KB903248_gene4281	7.062e-231	726.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4DYPX@85010|Pseudonocardiales	201174|Actinobacteria	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
TLS3_k127_2683438_1	1120948.KB903246_gene3264	1.507e-176	570.0	COG3290@1|root,COG3290@2|Bacteria,2GIRZ@201174|Actinobacteria,4DYCI@85010|Pseudonocardiales	201174|Actinobacteria	T	Signal transduction histidine kinase regulating citrate malate metabolism	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_4,PAS_8,sCache_3_2
TLS3_k127_2683438_2	1120948.KB903246_gene3265	1.332e-64	228.0	COG0745@1|root,COG0745@2|Bacteria,2GKJK@201174|Actinobacteria,4E0WI@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_2683438_3	1397278.AYMV01000051_gene2513	0.000355	46.0	COG0745@1|root,COG0745@2|Bacteria,2GKJK@201174|Actinobacteria,4FR8I@85023|Microbacteriaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_2683438_0	1120948.KB903246_gene3266	2.755e-232	727.0	COG1301@1|root,COG1301@2|Bacteria,2GK6U@201174|Actinobacteria,4DXM6@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	dctA	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
TLS3_k127_2689264_3	1123024.AUII01000003_gene3326	0.0002615	48.0	COG2834@1|root,COG2834@2|Bacteria,2GKA2@201174|Actinobacteria,4DYPF@85010|Pseudonocardiales	201174|Actinobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2092,MucB_RseB
TLS3_k127_2689264_2	1123024.AUII01000003_gene3327	5.804e-92	310.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4E0FJ@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_2689264_0	1123024.AUII01000003_gene3328	2.884e-136	457.0	COG0642@1|root,COG2205@2|Bacteria,2GNUQ@201174|Actinobacteria,4DZ34@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_2689264_1	1120948.KB903229_gene5296	1.695e-95	320.0	COG0697@1|root,COG0697@2|Bacteria,2IPHX@201174|Actinobacteria,4E7TM@85010|Pseudonocardiales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_2703810_3	1120948.KB903244_gene3163	7.657e-20	88.0	COG0024@1|root,COG0024@2|Bacteria,2GKIZ@201174|Actinobacteria,4E03C@85010|Pseudonocardiales	201174|Actinobacteria	E	Methionine aminopeptidase	map	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
TLS3_k127_2703810_0	1120948.KB903244_gene3162	2.761e-127	417.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,4E17G@85010|Pseudonocardiales	201174|Actinobacteria	H	RibD C-terminal domain	ribG	-	1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
TLS3_k127_2703810_2	675635.Psed_4704	1.541e-71	246.0	COG3576@1|root,COG3576@2|Bacteria,2GKCF@201174|Actinobacteria,4DZ2B@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
TLS3_k127_2703810_1	1120948.KB903244_gene3118	1.826e-76	261.0	COG1492@1|root,COG1492@2|Bacteria,2GJ1W@201174|Actinobacteria,4DYZN@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA,GATase_3
TLS3_k127_2708237_5	1120948.KB903240_gene3772	1.012e-26	119.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4DX5D@85010|Pseudonocardiales	201174|Actinobacteria	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TLS3_k127_2708237_1	1120948.KB903240_gene3771	8.582e-143	462.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,4DYXM@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	pafB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
TLS3_k127_2708237_2	1120948.KB903240_gene3770	8.71e-136	456.0	COG2378@1|root,COG2378@2|Bacteria,2GMAU@201174|Actinobacteria,4DY44@85010|Pseudonocardiales	201174|Actinobacteria	K	overlaps another CDS with the same product name	pafC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
TLS3_k127_2708237_0	1463921.JODF01000002_gene3049	5.151e-229	724.0	COG0488@1|root,COG0488@2|Bacteria,2GK9S@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	-	-	-	ko:K18230	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000	3.A.1.120	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_2708237_6	1120948.KB903240_gene3768	2.316e-20	93.0	COG1826@1|root,COG1826@2|Bacteria,2GQQX@201174|Actinobacteria,4E7F3@85010|Pseudonocardiales	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	GO:0008150,GO:0040007	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
TLS3_k127_2708237_3	1123024.AUII01000035_gene1209	3.131e-111	371.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,4DYCT@85010|Pseudonocardiales	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
TLS3_k127_2708237_4	1120948.KB903240_gene3767	1.286e-72	246.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,4DXSA@85010|Pseudonocardiales	201174|Actinobacteria	L	DEAD DEAH box helicase	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
TLS3_k127_2711074_5	66897.DJ64_23480	1.312e-64	237.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_2711074_6	1463858.JOHR01000004_gene1612	2.535e-60	214.0	COG1309@1|root,COG1309@2|Bacteria,2GM4I@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_2711074_0	1123024.AUII01000013_gene458	7.845e-178	567.0	COG0075@1|root,COG0075@2|Bacteria,2GM5F@201174|Actinobacteria,4E1KQ@85010|Pseudonocardiales	201174|Actinobacteria	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
TLS3_k127_2711074_3	1120950.KB892799_gene2163	4.291e-96	321.0	COG0394@1|root,COG0640@1|root,COG0394@2|Bacteria,COG0640@2|Bacteria,2IB1N@201174|Actinobacteria,4DQ6K@85009|Propionibacteriales	201174|Actinobacteria	K	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	HTH_20,HTH_5,LMWPc
TLS3_k127_2711074_1	1211815.CBYP010000019_gene2867	4.607e-174	555.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4ERYR@85013|Frankiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
TLS3_k127_2711074_4	1246445.ANAY01000003_gene2981	5.718e-92	329.0	COG0583@1|root,COG0583@2|Bacteria,2GPBM@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
TLS3_k127_2711074_2	1246445.ANAY01000003_gene2980	5.246e-154	495.0	COG2175@1|root,COG2175@2|Bacteria,2I53F@201174|Actinobacteria	201174|Actinobacteria	Q	Protein of unknown function (DUF971)	-	-	1.14.11.1	ko:K00471	ko00310,map00310	-	R02397	RC00709	ko00000,ko00001,ko01000	-	-	-	DUF971,TauD
TLS3_k127_2711720_3	645465.ACUR01000464_gene1080	6.372e-16	78.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria	201174|Actinobacteria	J	Phenazine biosynthesis protein PhzF	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
TLS3_k127_2711720_0	1289387.AUKW01000009_gene4242	1.268e-170	566.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
TLS3_k127_2711720_1	298655.KI912266_gene2098	5.134e-74	257.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EU8G@85013|Frankiales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
TLS3_k127_2717880_4	1278078.G419_03073	1.153e-57	216.0	2EX3R@1|root,33QES@2|Bacteria,2GMEF@201174|Actinobacteria,4FVTY@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2717880_1	1120948.KB903246_gene3388	1.44e-118	396.0	COG4760@1|root,COG4760@2|Bacteria,2GNCK@201174|Actinobacteria,4E12K@85010|Pseudonocardiales	201174|Actinobacteria	S	Bax inhibitor 1 like	-	-	-	-	-	-	-	-	-	-	-	-	BaxI_1
TLS3_k127_2717880_0	1120948.KB903246_gene3390	0.0	1123.0	COG2208@1|root,COG2208@2|Bacteria,2GKEF@201174|Actinobacteria,4EEDR@85010|Pseudonocardiales	201174|Actinobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,PAS_8,PAS_9,SpoIIE
TLS3_k127_2717880_3	1120948.KB903246_gene3391	1.377e-98	331.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TLS3_k127_2717880_2	1449068.JMLQ01000001_gene229	6.837e-110	362.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4FVAW@85025|Nocardiaceae	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	udgB	GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
TLS3_k127_2725950_2	1120948.KB903244_gene3091	7.849e-124	402.0	COG0215@1|root,COG0215@2|Bacteria,2GJ4W@201174|Actinobacteria,4E1NY@85010|Pseudonocardiales	201174|Actinobacteria	J	PFAM tRNA synthetases class I (C) catalytic domain	-	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
TLS3_k127_2725950_3	1120948.KB903244_gene3090	1.479e-15	90.0	COG3266@1|root,COG3266@2|Bacteria,2I44K@201174|Actinobacteria,4DZUJ@85010|Pseudonocardiales	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2725950_0	1120948.KB903244_gene3089	1.329e-313	974.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4DXJY@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
TLS3_k127_2725950_4	1122997.AUDD01000002_gene1077	1.693e-11	70.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,Trans_reg_C
TLS3_k127_2725950_1	1120948.KB903244_gene3086	1.634e-163	520.0	COG0477@1|root,COG2814@2|Bacteria,2GK8C@201174|Actinobacteria,4DZMT@85010|Pseudonocardiales	201174|Actinobacteria	EGP	arabinose efflux permease	-	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1,Sugar_tr
TLS3_k127_2729964_1	1120948.KB903217_gene1604	2.124e-64	223.0	2DHRC@1|root,32U9K@2|Bacteria,2II2K@201174|Actinobacteria,4E4I1@85010|Pseudonocardiales	201174|Actinobacteria	S	Family of unknown function (DUF5319)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5319
TLS3_k127_2729964_0	1120948.KB903217_gene1605	5.415e-278	862.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GITZ@201174|Actinobacteria,4DXV8@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
TLS3_k127_2729964_2	1120948.KB903217_gene1606	1.212e-09	59.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4DY36@85010|Pseudonocardiales	201174|Actinobacteria	F	IMP dehydrogenase GMP reductase	guaB3	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
TLS3_k127_2732753_1	1120948.KB903243_gene2581	1.522e-57	204.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria,4DZG4@85010|Pseudonocardiales	201174|Actinobacteria	E	Glucose-methanol-choline oxidoreductase	betA	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
TLS3_k127_2732753_0	1120948.KB903243_gene2581	1.726e-116	385.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria,4DZG4@85010|Pseudonocardiales	201174|Actinobacteria	E	Glucose-methanol-choline oxidoreductase	betA	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
TLS3_k127_2732753_2	1120948.KB903243_gene2582	2.161e-05	46.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4DX4V@85010|Pseudonocardiales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
TLS3_k127_2734114_2	1120948.KB903244_gene3066	0.0007876	47.0	2C038@1|root,347CF@2|Bacteria,2GWPX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2734114_1	1120948.KB903246_gene3239	1.044e-82	277.0	COG0346@1|root,COG0346@2|Bacteria,2IK9V@201174|Actinobacteria,4EB6C@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_2734114_0	1120948.KB903244_gene3068	1.846e-85	286.0	COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria,4DZN6@85010|Pseudonocardiales	201174|Actinobacteria	V	efflux protein, MATE family	dinF	-	-	-	-	-	-	-	-	-	-	-	MatE
TLS3_k127_2742872_0	882086.SacxiDRAFT_3893	1.194e-106	354.0	COG0730@1|root,COG0730@2|Bacteria,2GNPE@201174|Actinobacteria	201174|Actinobacteria	S	membrane transporter protein	cysZ	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_2742872_1	1120948.KB903229_gene5098	7.029e-80	288.0	COG1011@1|root,COG1011@2|Bacteria,2GN5U@201174|Actinobacteria,4E03B@85010|Pseudonocardiales	201174|Actinobacteria	S	Haloacid dehalogenase superfamily, subfamily IA, variant 2 with 3rd motif like haloacid dehalogenase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
TLS3_k127_2742872_3	994479.GL877879_gene6130	4.26e-08	57.0	2DCWN@1|root,2ZFMB@2|Bacteria,2H15F@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
TLS3_k127_2742872_2	700508.D174_01395	5.114e-20	91.0	COG0642@1|root,COG2205@2|Bacteria,2GMYP@201174|Actinobacteria,236T1@1762|Mycobacteriaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_274724_4	1463858.JOHR01000023_gene3932	9.065e-25	104.0	COG2318@1|root,COG2318@2|Bacteria,2GMS2@201174|Actinobacteria	201174|Actinobacteria	E	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
TLS3_k127_274724_0	1120948.KB903219_gene739	1.8e-194	618.0	COG2270@1|root,COG2270@2|Bacteria,2GJCW@201174|Actinobacteria,4E1YM@85010|Pseudonocardiales	201174|Actinobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
TLS3_k127_274724_7	675635.Psed_0951	0.0006363	46.0	2907B@1|root,2ZMX4@2|Bacteria,2HB25@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_274724_6	675635.Psed_0951	7.818e-06	56.0	2907B@1|root,2ZMX4@2|Bacteria,2HB25@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_274724_2	1120948.KB903219_gene740	4.645e-57	207.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria,4E4QT@85010|Pseudonocardiales	201174|Actinobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
TLS3_k127_274724_3	1306174.JODP01000002_gene5808	4.145e-35	141.0	COG0454@1|root,COG0456@2|Bacteria,2IG3K@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_274724_1	1120948.KB903219_gene742	1.547e-130	437.0	COG1835@1|root,COG1835@2|Bacteria,2HEK8@201174|Actinobacteria,4E5NB@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS3_k127_2750533_4	1122138.AQUZ01000045_gene4493	9.39e-93	323.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,2I2QY@201174|Actinobacteria,4DPUE@85009|Propionibacteriales	201174|Actinobacteria	T	Domain of unknown function (DUF4173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173,HAMP,HATPase_c,HisKA
TLS3_k127_2750533_2	1122138.AQUZ01000045_gene4492	3.389e-107	354.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4DN8S@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	cseB	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_2750533_0	1179773.BN6_34540	1.526e-131	429.0	COG0385@1|root,COG0385@2|Bacteria,2GMAM@201174|Actinobacteria,4E1U1@85010|Pseudonocardiales	201174|Actinobacteria	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
TLS3_k127_2750533_1	1289387.AUKW01000003_gene2632	9.641e-122	412.0	COG3386@1|root,COG3386@2|Bacteria,2HE8D@201174|Actinobacteria	201174|Actinobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	3.1.1.15	ko:K13874,ko:K14274	ko00040,ko00053,ko01100,map00040,map00053,map01100	-	R02427,R02526	RC00537,RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
TLS3_k127_2750533_3	479432.Sros_5343	9.908e-105	354.0	COG2124@1|root,COG2124@2|Bacteria,2IANG@201174|Actinobacteria,4EM3X@85012|Streptosporangiales	201174|Actinobacteria	C	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
TLS3_k127_2750533_5	1237500.ANBA01000007_gene2879	7.121e-34	137.0	COG1846@1|root,COG1846@2|Bacteria,2IP25@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
TLS3_k127_2773988_8	1120948.KB903219_gene701	1.251e-21	96.0	COG2246@1|root,COG2246@2|Bacteria,2IIGF@201174|Actinobacteria,4E5UI@85010|Pseudonocardiales	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
TLS3_k127_2773988_7	1120948.KB903219_gene702	2.036e-33	145.0	COG1716@1|root,COG1716@2|Bacteria,2GK5I@201174|Actinobacteria,4E5TU@85010|Pseudonocardiales	201174|Actinobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
TLS3_k127_2773988_3	1120948.KB903219_gene703	1.729e-86	302.0	COG0631@1|root,COG0631@2|Bacteria,2GKDM@201174|Actinobacteria,4E20G@85010|Pseudonocardiales	201174|Actinobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	prpB10	-	-	-	-	-	-	-	-	-	-	-	DZR,PP2C_2
TLS3_k127_2773988_4	1120948.KB903219_gene704	2.059e-57	216.0	COG0515@1|root,COG0515@2|Bacteria,2GJ24@201174|Actinobacteria,4DY0I@85010|Pseudonocardiales	201174|Actinobacteria	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K14949	ko05152,map05152	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	Pkinase,PknG_TPR,PknG_rubred
TLS3_k127_2773988_5	1120948.KB903219_gene708	5.881e-46	176.0	2E6DR@1|root,3311A@2|Bacteria,2IKTW@201174|Actinobacteria,4E80Y@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2773988_0	1120948.KB903219_gene710	4.83e-299	922.0	COG4108@1|root,COG4108@2|Bacteria,2GKQA@201174|Actinobacteria,4DZCU@85010|Pseudonocardiales	201174|Actinobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,RF3_C
TLS3_k127_2773988_2	1120948.KB903219_gene711	1.854e-163	531.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4DZ8H@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_2773988_6	1120948.KB903219_gene712	7.104e-35	135.0	2BDAW@1|root,326ZI@2|Bacteria,2HSCI@201174|Actinobacteria,4ED9E@85010|Pseudonocardiales	201174|Actinobacteria	S	PASTA domain	-	-	-	-	-	-	-	-	-	-	-	-	PASTA
TLS3_k127_2773988_9	2074.JNYD01000044_gene2257	9.056e-20	98.0	COG2172@1|root,COG2172@2|Bacteria,2GV8N@201174|Actinobacteria,4E774@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
TLS3_k127_2773988_1	1120948.KB903219_gene713	1.272e-199	634.0	COG0596@1|root,COG0596@2|Bacteria,2GJYS@201174|Actinobacteria,4DZB9@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
TLS3_k127_2790624_1	1449976.KALB_5129	1.829e-173	552.0	COG0110@1|root,COG0663@1|root,COG1020@1|root,COG0110@2|Bacteria,COG0663@2|Bacteria,COG1020@2|Bacteria,2I8TI@201174|Actinobacteria,4EF88@85010|Pseudonocardiales	201174|Actinobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Hexapep,Hexapep_2,PP-binding
TLS3_k127_2790624_7	58344.JOEL01000001_gene412	1.107e-71	253.0	COG4285@1|root,COG4285@2|Bacteria,2GNQ0@201174|Actinobacteria	201174|Actinobacteria	S	Biotin-protein ligase, N terminal	-	-	-	-	-	-	-	-	-	-	-	-	BPL_N
TLS3_k127_2790624_4	405948.SACE_3227	2.76e-139	456.0	COG0308@1|root,COG0308@2|Bacteria,2IAPJ@201174|Actinobacteria,4DYC0@85010|Pseudonocardiales	201174|Actinobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Peptidase_M1,Peptidase_M6
TLS3_k127_2790624_5	2074.JNYD01000015_gene4498	4.877e-94	327.0	COG3503@1|root,COG3503@2|Bacteria,2I2JM@201174|Actinobacteria,4E008@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF418
TLS3_k127_2790624_10	2074.JNYD01000001_gene6278	5.924e-49	201.0	COG0443@1|root,COG3391@1|root,COG0443@2|Bacteria,COG3391@2|Bacteria,2GNTE@201174|Actinobacteria,4E043@85010|Pseudonocardiales	201174|Actinobacteria	O	Hsp70 protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
TLS3_k127_2790624_8	1123024.AUII01000014_gene4277	3.343e-66	248.0	COG0637@1|root,COG0637@2|Bacteria,2GMIQ@201174|Actinobacteria,4EEJB@85010|Pseudonocardiales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
TLS3_k127_2790624_2	1123024.AUII01000037_gene4376	2.002e-157	503.0	COG0572@1|root,COG0572@2|Bacteria,2I98W@201174|Actinobacteria,4E9H9@85010|Pseudonocardiales	201174|Actinobacteria	F	Phosphoribulokinase / Uridine kinase family	udk	-	2.7.1.19,2.7.1.48	ko:K00855,ko:K00876	ko00240,ko00710,ko00983,ko01100,ko01120,ko01200,map00240,map00710,map00983,map01100,map01120,map01200	M00165,M00166	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01523,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
TLS3_k127_2790624_6	675635.Psed_6245	2.012e-90	307.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4EA0P@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_2790624_3	1123024.AUII01000037_gene4380	2.943e-143	479.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria,4E9TW@85010|Pseudonocardiales	201174|Actinobacteria	T	GAF domain	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
TLS3_k127_2790624_0	258533.BN977_00627	7.742e-280	863.0	COG1850@1|root,COG1850@2|Bacteria,2HFXU@201174|Actinobacteria,2354C@1762|Mycobacteriaceae	201174|Actinobacteria	G	Ribulose bisphosphate carboxylase large chain, catalytic domain	cbbL	-	4.1.1.39,5.3.2.5	ko:K01601,ko:K08965	ko00270,ko00630,ko00710,ko01100,ko01120,ko01200,map00270,map00630,map00710,map01100,map01120,map01200	M00034,M00165,M00166,M00532	R00024,R03140,R07393	RC00172,RC00859,RC02421	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
TLS3_k127_2790624_9	675635.Psed_6250	4.151e-60	231.0	COG4451@1|root,COG4451@2|Bacteria,2IIFC@201174|Actinobacteria,4EBJA@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Ribulose bisphosphate carboxylase, small chain	cbxSC	-	4.1.1.39	ko:K01602	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_small
TLS3_k127_2790624_11	1380386.JIAW01000009_gene5480	6.329e-43	168.0	COG0464@1|root,COG0464@2|Bacteria,2GJWA@201174|Actinobacteria,234RI@1762|Mycobacteriaceae	201174|Actinobacteria	O	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
TLS3_k127_2791015_6	1120948.KB903248_gene4279	8.518e-25	105.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4DYWZ@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2158c	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_2791015_4	1120948.KB903248_gene4278	1.084e-189	608.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4DZ1W@85010|Pseudonocardiales	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	GO:0008150,GO:0040007	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_2791015_3	1120948.KB903248_gene4277	8.163e-196	643.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4DXGI@85010|Pseudonocardiales	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0008150,GO:0040007	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
TLS3_k127_2791015_1	1120948.KB903248_gene4276	7.87e-209	659.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4DXZN@85010|Pseudonocardiales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2155c	AlaDh_PNT_C,Mur_ligase_C,Mur_ligase_M
TLS3_k127_2791015_2	1120948.KB903248_gene4275	9.23e-198	626.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4DXX1@85010|Pseudonocardiales	201174|Actinobacteria	D	Belongs to the SEDS family	ftsW	GO:0008150,GO:0040007	2.4.1.227	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	2.A.103.1	GT28	-	FTSW_RODA_SPOVE
TLS3_k127_2791015_5	1120948.KB903248_gene4274	2.237e-150	486.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,4DY3X@85010|Pseudonocardiales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
TLS3_k127_2791015_0	1120948.KB903248_gene4273	7.307e-256	804.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4DYX2@85010|Pseudonocardiales	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
TLS3_k127_2792346_2	1120948.KB903243_gene2304	1.673e-72	261.0	COG0026@1|root,COG0026@2|Bacteria,2GJCU@201174|Actinobacteria,4DXPI@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
TLS3_k127_2792346_1	1120948.KB903243_gene2305	9.922e-81	299.0	2C2NP@1|root,334Y5@2|Bacteria,2IDXP@201174|Actinobacteria,4E42Q@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2792346_0	1120948.KB903243_gene2306	7.545e-124	434.0	COG1595@1|root,COG1595@2|Bacteria,2GJFK@201174|Actinobacteria,4E0JT@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
TLS3_k127_2792346_3	1120948.KB903243_gene2311	2.325e-63	222.0	COG2246@1|root,COG2246@2|Bacteria,2IFFV@201174|Actinobacteria,4E042@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
TLS3_k127_279592_10	37919.EP51_37075	3.125e-19	99.0	COG1055@1|root,COG1055@2|Bacteria,2GMQJ@201174|Actinobacteria,4FXZJ@85025|Nocardiaceae	201174|Actinobacteria	P	Arsenical pump membrane protein	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
TLS3_k127_279592_1	1120948.KB903248_gene4384	4.803e-100	337.0	COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria,4E3FN@85010|Pseudonocardiales	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_279592_11	345341.KUTG_04140	6.661e-19	96.0	2DTR4@1|root,33MCB@2|Bacteria,2HAJT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_279592_6	1380346.JNIH01000027_gene5748	7.908e-40	165.0	COG2203@1|root,COG2203@2|Bacteria,2I2QK@201174|Actinobacteria	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
TLS3_k127_279592_0	1157943.KB892705_gene1813	1.195e-119	392.0	COG0412@1|root,COG0412@2|Bacteria,2HVNP@201174|Actinobacteria,2353Q@1762|Mycobacteriaceae	201174|Actinobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
TLS3_k127_279592_3	1120948.KB903218_gene2159	1.609e-68	239.0	COG0412@1|root,COG0412@2|Bacteria,2GJMH@201174|Actinobacteria,4E0MC@85010|Pseudonocardiales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
TLS3_k127_279592_7	1120948.KB903218_gene1769	5.284e-37	149.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Beta_helix,Cellulose_synt,DUF3131,Glycos_transf_2
TLS3_k127_279592_4	1123024.AUII01000013_gene333	5.421e-67	236.0	COG3631@1|root,COG3631@2|Bacteria,2GR1G@201174|Actinobacteria,4EDKX@85010|Pseudonocardiales	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
TLS3_k127_279592_8	1048339.KB913029_gene1555	9.018e-36	140.0	COG2076@1|root,COG2076@2|Bacteria,2IQND@201174|Actinobacteria,4ETK0@85013|Frankiales	201174|Actinobacteria	P	Small multidrug resistance protein	sugE	-	-	ko:K03297,ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
TLS3_k127_279592_2	1246995.AFR_08505	5.421e-89	308.0	COG2376@1|root,COG2376@2|Bacteria,2GJV9@201174|Actinobacteria,4DBPP@85008|Micromonosporales	201174|Actinobacteria	G	Dihydroxyacetone kinase	dhaK2	-	2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15	ko:K00863,ko:K05878	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	M00344	R01011,R01012,R01059	RC00002,RC00015,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Dak1,Dak2
TLS3_k127_279592_5	1068978.AMETH_4350	7.885e-62	223.0	COG0726@1|root,COG0726@2|Bacteria,2GN6G@201174|Actinobacteria,4E4NT@85010|Pseudonocardiales	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K14659,ko:K22278	-	M00664	-	-	ko00000,ko00002,ko01000	-	-	-	Polysacc_deac_1
TLS3_k127_279592_9	675635.Psed_5146	1.852e-26	109.0	COG3576@1|root,COG3576@2|Bacteria,2I3RW@201174|Actinobacteria,4EF7T@85010|Pseudonocardiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
TLS3_k127_2800093_0	1120948.KB903217_gene1031	2.346e-266	833.0	COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria,4DX7H@85010|Pseudonocardiales	201174|Actinobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,TspO_MBR
TLS3_k127_2820282_2	1120948.KB903243_gene2394	1.957e-60	220.0	2E29A@1|root,30QXH@2|Bacteria,2H74E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2820282_1	1120948.KB903243_gene2391	3.045e-159	523.0	COG2141@1|root,COG2141@2|Bacteria,2IDX7@201174|Actinobacteria,4EBHH@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
TLS3_k127_2820282_0	1120948.KB903243_gene2390	2.494e-231	744.0	COG1020@1|root,COG1020@2|Bacteria,2GP0R@201174|Actinobacteria,4E14R@85010|Pseudonocardiales	201174|Actinobacteria	Q	AMP-binding enzyme C-terminal domain	-	-	-	ko:K21780	ko00333,map00333	M00837,M00838	R06746	RC00039,RC01438	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_2821310_10	1120948.KB903218_gene2263	8.764e-39	148.0	COG2066@1|root,COG2066@2|Bacteria,2GKAV@201174|Actinobacteria,4E1TG@85010|Pseudonocardiales	201174|Actinobacteria	E	Glutaminase	glsA	GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
TLS3_k127_2821310_0	1120948.KB903217_gene1328	0.0	1998.0	COG1643@1|root,COG1643@2|Bacteria,2GIWX@201174|Actinobacteria,4E02F@85010|Pseudonocardiales	201174|Actinobacteria	L	TIGRFAM ATP-dependent helicase HrpA	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
TLS3_k127_2821310_7	365528.KB891225_gene1234	4.697e-59	211.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4ESTA@85013|Frankiales	201174|Actinobacteria	K	PFAM sigma-70 region 2 domain protein	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_2821310_2	298654.FraEuI1c_5728	5.004e-120	411.0	COG0699@1|root,COG0699@2|Bacteria,2GK6T@201174|Actinobacteria	201174|Actinobacteria	T	GTPases (dynamin-related)	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N,MMR_HSR1
TLS3_k127_2821310_8	1449069.JMLO01000005_gene1575	5.602e-56	222.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,4FW88@85025|Nocardiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknE	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Pro_isomerase,SBP_bac_3
TLS3_k127_2821310_14	585529.HMPREF0291_11081	1.041e-07	59.0	29XSE@1|root,30JI8@2|Bacteria,2GQU7@201174|Actinobacteria,22ND8@1653|Corynebacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2821310_13	365528.KB891225_gene1236	2.612e-21	111.0	COG0576@1|root,COG0576@2|Bacteria,2IRT9@201174|Actinobacteria	201174|Actinobacteria	O	Molecular chaperone GrpE (Heat shock	-	-	-	-	-	-	-	-	-	-	-	-	GrpE
TLS3_k127_2821310_4	365528.KB891225_gene1237	6.872e-105	368.0	COG0699@1|root,COG0699@2|Bacteria,2GNGP@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Dynamin family	iniA	GO:0003674,GO:0005215,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015562,GO:0016020,GO:0022857,GO:0030312,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	Dynamin_N
TLS3_k127_2821310_5	298654.FraEuI1c_5734	5.016e-96	339.0	COG0443@1|root,COG1520@1|root,COG0443@2|Bacteria,COG1520@2|Bacteria,2GMNN@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the heat shock protein 70 family	-	-	-	-	-	-	-	-	-	-	-	-	HSP70,PQQ_3
TLS3_k127_2821310_11	1120948.KB903217_gene1330	2.275e-29	121.0	2BF92@1|root,3291X@2|Bacteria,2HP0R@201174|Actinobacteria,4E7IB@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2821310_6	1120948.KB903217_gene1331	2.701e-73	251.0	COG1832@1|root,COG1832@2|Bacteria,2IHSP@201174|Actinobacteria,4E30F@85010|Pseudonocardiales	201174|Actinobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
TLS3_k127_2821310_1	1120948.KB903217_gene1332	5.199e-242	752.0	COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4DYF3@85010|Pseudonocardiales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	cysD	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
TLS3_k127_2821310_12	479433.Caci_2282	6.814e-24	117.0	2DJKR@1|root,32X86@2|Bacteria,2I86E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2821310_15	909613.UO65_1115	4.067e-07	59.0	COG1716@1|root,COG1716@2|Bacteria,2GSQ0@201174|Actinobacteria,4E6F6@85010|Pseudonocardiales	201174|Actinobacteria	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2821310_9	247156.NFA_28900	9.123e-51	185.0	COG1670@1|root,COG1670@2|Bacteria,2IT84@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TLS3_k127_2821310_3	525909.Afer_1029	3.048e-118	384.0	COG1960@1|root,COG1960@2|Bacteria,2HF8P@201174|Actinobacteria,4CNQ3@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K11731	ko00281,map00281	-	R08089	RC01893	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_2830973_7	1120948.KB903248_gene4196	2.349e-87	310.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4DYMZ@85010|Pseudonocardiales	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
TLS3_k127_2830973_3	1449976.KALB_6452	6.996e-164	535.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4DX7N@85010|Pseudonocardiales	201174|Actinobacteria	E	TIGRFAM acetylornithine and succinylornithine	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS3_k127_2830973_4	1120948.KB903248_gene4198	5.773e-152	505.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4DXB3@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
TLS3_k127_2830973_0	1120948.KB903248_gene4199	2.238e-190	602.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4E0VH@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
TLS3_k127_2830973_1	1120948.KB903248_gene4200	4.592e-179	565.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4E0DP@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
TLS3_k127_2830973_2	1120948.KB903248_gene4201	4.271e-166	548.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4DXU1@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH dehydrogenase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_2830973_5	526225.Gobs_1330	8.857e-94	323.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4EVS8@85013|Frankiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
TLS3_k127_2830973_6	1120948.KB903248_gene4205	1.921e-87	296.0	COG1073@1|root,COG1073@2|Bacteria,2IGDR@201174|Actinobacteria,4DYZU@85010|Pseudonocardiales	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S9
TLS3_k127_2830973_9	211114.JOEF01000041_gene6037	3.022e-33	136.0	COG1309@1|root,COG1309@2|Bacteria,2IRQG@201174|Actinobacteria,4ECPU@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
TLS3_k127_2830973_8	1120948.KB903248_gene4207	5.276e-81	273.0	COG0072@1|root,COG0072@2|Bacteria,2GMFD@201174|Actinobacteria,4DYCC@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
TLS3_k127_2833207_0	1120948.KB903219_gene625	4.733e-202	631.0	COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4E1GK@85010|Pseudonocardiales	201174|Actinobacteria	E	Methionine synthase	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
TLS3_k127_2833207_1	1120948.KB903219_gene626	1.213e-78	280.0	COG5340@1|root,COG5340@2|Bacteria,2I4A3@201174|Actinobacteria	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2833207_2	1120948.KB903217_gene1316	1.384e-68	234.0	COG2151@1|root,COG2151@2|Bacteria,2IAEQ@201174|Actinobacteria,4E453@85010|Pseudonocardiales	201174|Actinobacteria	S	metal-sulfur cluster biosynthetic enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
TLS3_k127_2844137_8	1120948.KB903240_gene3999	5.683e-69	237.0	COG0362@1|root,COG0362@2|Bacteria,2GJ2J@201174|Actinobacteria,4DZCG@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
TLS3_k127_2844137_9	1265310.CCBD010000055_gene1427	5.232e-54	196.0	2AW22@1|root,31MWT@2|Bacteria,2IKWE@201174|Actinobacteria,238T9@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1360)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1360
TLS3_k127_2844137_6	1120948.KB903240_gene4000	6.362e-88	299.0	COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria,4E2S2@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
TLS3_k127_2844137_0	1120948.KB903240_gene4005	0.0	1104.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4DXF5@85010|Pseudonocardiales	201174|Actinobacteria	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
TLS3_k127_2844137_7	1120948.KB903240_gene4006	5.757e-79	280.0	COG0665@1|root,COG0665@2|Bacteria,2HS67@201174|Actinobacteria,4ECIV@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
TLS3_k127_2844137_4	1120948.KB903240_gene4008	1.102e-100	340.0	COG1846@1|root,COG1846@2|Bacteria,2GMDI@201174|Actinobacteria,4E0V0@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2844137_5	1120948.KB903240_gene4009	9.675e-98	328.0	COG1075@1|root,COG1075@2|Bacteria,2IH84@201174|Actinobacteria,4E3RJ@85010|Pseudonocardiales	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	PGAP1
TLS3_k127_2844137_2	1120948.KB903240_gene4013	1.092e-130	433.0	COG1277@1|root,COG1277@2|Bacteria,2GP6D@201174|Actinobacteria,4DZKQ@85010|Pseudonocardiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
TLS3_k127_2844137_1	1120948.KB903240_gene4014	5.538e-131	432.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria,4E0N5@85010|Pseudonocardiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_2844137_3	1120948.KB903240_gene4015	1.175e-122	403.0	COG3026@1|root,COG3026@2|Bacteria,2I3RC@201174|Actinobacteria,4EF73@85010|Pseudonocardiales	201174|Actinobacteria	T	antisigma factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2859719_1	1120948.KB903244_gene2998	2.153e-47	186.0	COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria,4E4K7@85010|Pseudonocardiales	201174|Actinobacteria	S	Modulates RecA activity	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
TLS3_k127_2859719_0	1120948.KB903244_gene2999	2.153e-200	634.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4DZ5K@85010|Pseudonocardiales	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
TLS3_k127_2859719_2	1120948.KB903244_gene3000	5.558e-22	95.0	2EFU9@1|root,339KE@2|Bacteria,2GQJW@201174|Actinobacteria,4E6KE@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3046)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3046
TLS3_k127_2860879_0	1120948.KB903244_gene2861	1.311e-243	757.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4DXY8@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
TLS3_k127_2860879_4	1120948.KB903244_gene2862	1.404e-86	291.0	COG3963@1|root,COG3963@2|Bacteria,2I93P@201174|Actinobacteria,4E3Y8@85010|Pseudonocardiales	201174|Actinobacteria	I	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,RrnaAD
TLS3_k127_2860879_3	330084.JNYZ01000024_gene2508	3.056e-91	331.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4E93D@85010|Pseudonocardiales	201174|Actinobacteria	S	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_2860879_1	1120948.KB903244_gene2864	6.135e-186	590.0	COG2159@1|root,COG2159@2|Bacteria,2GKCJ@201174|Actinobacteria,4DYJI@85010|Pseudonocardiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
TLS3_k127_2860879_2	1120948.KB903244_gene2865	9.322e-186	594.0	COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4DY1H@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
TLS3_k127_2860879_5	1120948.KB903244_gene2866	2.679e-41	154.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,4DY5R@85010|Pseudonocardiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
TLS3_k127_2866116_2	105420.BBPO01000032_gene6514	4.816e-73	251.0	COG0451@1|root,COG0451@2|Bacteria,2GP24@201174|Actinobacteria,2NEQC@228398|Streptacidiphilus	201174|Actinobacteria	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS3_k127_2866116_1	101510.RHA1_ro01722	2.61e-193	623.0	COG1073@1|root,COG1073@2|Bacteria,2GUBY@201174|Actinobacteria,4FXYH@85025|Nocardiaceae	201174|Actinobacteria	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	BAAT_C,Bile_Hydr_Trans
TLS3_k127_2866116_3	436229.JOEH01000009_gene4427	4.714e-49	201.0	COG0657@1|root,COG0657@2|Bacteria,2I8XP@201174|Actinobacteria,2NGK3@228398|Streptacidiphilus	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
TLS3_k127_2866116_0	1120948.KB903217_gene1651	3.285e-211	662.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4DYYI@85010|Pseudonocardiales	201174|Actinobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
TLS3_k127_2869749_2	1120948.KB903244_gene3010	1.058e-163	517.0	COG0266@1|root,COG0266@2|Bacteria,2GKCW@201174|Actinobacteria,4E0U9@85010|Pseudonocardiales	201174|Actinobacteria	L	glycosylase	nei	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
TLS3_k127_2869749_15	1120949.KB903317_gene1588	5.483e-16	94.0	COG0457@1|root,COG2197@1|root,COG0457@2|Bacteria,COG2197@2|Bacteria,2I3SK@201174|Actinobacteria,4DMTU@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_2869749_4	543632.JOJL01000020_gene664	4.328e-92	335.0	COG0457@1|root,COG2197@1|root,COG0457@2|Bacteria,COG2197@2|Bacteria,2I3SK@201174|Actinobacteria,4DMTU@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_2869749_13	543632.JOJL01000020_gene665	5.75e-27	119.0	2EQQS@1|root,33IAN@2|Bacteria,2GUY1@201174|Actinobacteria,4DKB8@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2869749_9	2074.JNYD01000003_gene3442	2.137e-70	244.0	arCOG09452@1|root,335JP@2|Bacteria,2IBPA@201174|Actinobacteria,4E25A@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2869749_11	561175.KB894095_gene2273	1.233e-38	152.0	COG3548@1|root,COG3548@2|Bacteria,2IQG2@201174|Actinobacteria,4EQPI@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
TLS3_k127_2869749_16	2074.JNYD01000046_gene7303	0.0001558	53.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4E32T@85010|Pseudonocardiales	201174|Actinobacteria	L	HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH
TLS3_k127_2869749_10	675635.Psed_4542	2.081e-57	204.0	COG4954@1|root,COG4954@2|Bacteria,2IFBK@201174|Actinobacteria,4E3QH@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2000)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2000
TLS3_k127_2869749_14	345341.KUTG_00889	1.217e-23	103.0	COG2207@1|root,COG2207@2|Bacteria,2GNEB@201174|Actinobacteria,4DY9K@85010|Pseudonocardiales	201174|Actinobacteria	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
TLS3_k127_2869749_7	1123023.JIAI01000022_gene2324	5.375e-79	274.0	COG2207@1|root,COG2207@2|Bacteria,2GNEB@201174|Actinobacteria,4DY9K@85010|Pseudonocardiales	201174|Actinobacteria	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
TLS3_k127_2869749_3	1120948.KB903244_gene3011	1.166e-122	398.0	COG1842@1|root,COG1842@2|Bacteria,2GJGD@201174|Actinobacteria,4DX9Y@85010|Pseudonocardiales	201174|Actinobacteria	KT	Phage shock protein A (IM30), suppresses sigma54-dependent transcription	pspA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044464,GO:0071944	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
TLS3_k127_2869749_12	1120948.KB903244_gene3012	3.819e-34	152.0	COG1396@1|root,COG1396@2|Bacteria,2GR3F@201174|Actinobacteria,4E4DT@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Helix-turn-helix	clgR	GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006109,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009268,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009987,GO:0010447,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0010675,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031347,GO:0031348,GO:0032268,GO:0032502,GO:0033554,GO:0035821,GO:0040007,GO:0042176,GO:0043207,GO:0043565,GO:0043620,GO:0044003,GO:0044110,GO:0044111,GO:0044114,GO:0044115,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0061136,GO:0062012,GO:0065007,GO:0075136,GO:0080090,GO:0080134,GO:0085016,GO:0090062,GO:0097159,GO:1901363,GO:1902680,GO:1902882,GO:1903050,GO:1903362,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_31
TLS3_k127_2869749_8	1120948.KB903244_gene3013	2.202e-78	273.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4DZ4U@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
TLS3_k127_2869749_1	1120948.KB903244_gene3014	7.625e-221	720.0	COG0621@1|root,COG0621@2|Bacteria,2GKRI@201174|Actinobacteria,4DX5V@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
TLS3_k127_2869749_6	1120948.KB903244_gene3015	1.088e-80	295.0	COG1246@1|root,COG1246@2|Bacteria,2GJBT@201174|Actinobacteria,4E2QK@85010|Pseudonocardiales	201174|Actinobacteria	E	N-acetylglutamate synthase	argA	GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
TLS3_k127_2869749_5	1380393.JHVP01000003_gene1183	7.419e-92	313.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4ESJ9@85013|Frankiales	201174|Actinobacteria	GM	epimerase dehydratase	galE4	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS3_k127_2869749_0	258052.JNYV01000001_gene515	1.358e-291	919.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,2M0US@2063|Kitasatospora	201174|Actinobacteria	D	Ftsk_gamma	ftsK	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
TLS3_k127_2877342_0	1120948.KB903244_gene2765	0.0	1335.0	COG4581@1|root,COG4581@2|Bacteria,2GJSV@201174|Actinobacteria,4DXMY@85010|Pseudonocardiales	201174|Actinobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
TLS3_k127_2877342_1	211114.JOEF01000034_gene1390	8.608e-108	363.0	COG2207@1|root,COG2207@2|Bacteria,2GK7Q@201174|Actinobacteria,4E3IM@85010|Pseudonocardiales	201174|Actinobacteria	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
TLS3_k127_2877342_2	2074.JNYD01000034_gene6407	1.99e-85	295.0	COG0702@1|root,COG0702@2|Bacteria,2GK71@201174|Actinobacteria,4E5U1@85010|Pseudonocardiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
TLS3_k127_2877342_3	1179773.BN6_81740	6.903e-18	83.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,4DY2W@85010|Pseudonocardiales	201174|Actinobacteria	L	Exodeoxyribonuclease III xth	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
TLS3_k127_2878387_5	211114.JOEF01000002_gene4320	9.008e-13	77.0	COG1595@1|root,COG1595@2|Bacteria,2GM8T@201174|Actinobacteria,4DY2F@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigD	GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS3_k127_2878387_3	1120948.KB903217_gene1684	4.07e-136	445.0	COG1686@1|root,COG1686@2|Bacteria,2GK3M@201174|Actinobacteria,4DXKV@85010|Pseudonocardiales	201174|Actinobacteria	M	Belongs to the peptidase S11 family	dac	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
TLS3_k127_2878387_2	1120948.KB903217_gene1685	9.569e-140	452.0	COG1196@1|root,COG1196@2|Bacteria,2I3RX@201174|Actinobacteria,4EF7V@85010|Pseudonocardiales	201174|Actinobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2878387_0	1120948.KB903217_gene1686	1.182e-207	657.0	28NCS@1|root,2ZBFQ@2|Bacteria,2GM5N@201174|Actinobacteria,4DYFP@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2878387_1	1120948.KB903217_gene1687	1.17e-145	467.0	COG2267@1|root,COG2267@2|Bacteria,2I3AI@201174|Actinobacteria,4E20I@85010|Pseudonocardiales	201174|Actinobacteria	I	hydrolase or acyltransferase of alpha beta superfamily	dhmA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
TLS3_k127_2878387_4	1120948.KB903217_gene1697	1.262e-92	310.0	COG0035@1|root,COG0035@2|Bacteria,2GPJE@201174|Actinobacteria,4DZ16@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
TLS3_k127_2880938_7	1120948.KB903240_gene3798	3.009e-57	201.0	COG5032@1|root,COG5032@2|Bacteria,2GME7@201174|Actinobacteria,4E044@85010|Pseudonocardiales	201174|Actinobacteria	BDLTU	PFAM Phosphatidylinositol 3- and 4-kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2880938_4	1120948.KB903240_gene3797	2.694e-117	392.0	COG2220@1|root,COG2220@2|Bacteria,2GNXJ@201174|Actinobacteria,4DYA7@85010|Pseudonocardiales	201174|Actinobacteria	S	Zn-dependent hydrolase of beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
TLS3_k127_2880938_3	1120948.KB903240_gene3796	8.243e-141	461.0	COG2223@1|root,COG2223@2|Bacteria,2GM9Q@201174|Actinobacteria,4EF6E@85010|Pseudonocardiales	201174|Actinobacteria	P	Major Facilitator Superfamily	garP	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_2880938_2	1150599.MPHLEI_20999	8.249e-143	456.0	COG1024@1|root,COG1024@2|Bacteria,2GJ1A@201174|Actinobacteria,232A4@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA15	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
TLS3_k127_2880938_5	479431.Namu_0877	3.704e-108	355.0	COG1028@1|root,COG1028@2|Bacteria,2HEWC@201174|Actinobacteria,4EV16@85013|Frankiales	201174|Actinobacteria	IQ	KR domain	-	-	-	ko:K07535	ko00362,ko01120,ko01220,map00362,map01120,map01220	M00540	R05582	RC00154	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
TLS3_k127_2880938_1	994479.GL877879_gene5333	1.784e-215	677.0	COG1239@1|root,COG1239@2|Bacteria,2GMRS@201174|Actinobacteria,4DXIY@85010|Pseudonocardiales	201174|Actinobacteria	H	Mg-chelatase subunit ChlI	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0958	Mg_chelatase,Sigma54_activat
TLS3_k127_2880938_0	1120948.KB903240_gene3793	0.0	1126.0	COG4867@1|root,COG4867@2|Bacteria,2H14W@201174|Actinobacteria,4E01X@85010|Pseudonocardiales	201174|Actinobacteria	S	von Willebrand factor, type A	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	VWA_2
TLS3_k127_2880938_6	287986.DV20_24645	5.146e-97	321.0	COG0215@1|root,COG0215@2|Bacteria,2GJZR@201174|Actinobacteria,4DYWB@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins	mshC	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iNJ661.Rv2130c	tRNA-synt_1e
TLS3_k127_2881577_5	2074.JNYD01000034_gene6407	1.807e-66	233.0	COG0702@1|root,COG0702@2|Bacteria,2GK71@201174|Actinobacteria,4E5U1@85010|Pseudonocardiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
TLS3_k127_2881577_2	1120948.KB903244_gene2767	4.035e-146	493.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,4DY2W@85010|Pseudonocardiales	201174|Actinobacteria	L	Exodeoxyribonuclease III xth	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
TLS3_k127_2881577_1	2074.JNYD01000042_gene2208	7.287e-175	577.0	COG2172@1|root,COG2203@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria,4DZ97@85010|Pseudonocardiales	201174|Actinobacteria	T	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,SpoIIE
TLS3_k127_2881577_7	675635.Psed_2382	5.11e-16	92.0	COG1366@1|root,COG1366@2|Bacteria,2GQY5@201174|Actinobacteria,4E6VT@85010|Pseudonocardiales	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS,STAS_2
TLS3_k127_2881577_6	1120948.KB903244_gene2769	1.282e-56	205.0	COG4276@1|root,COG4276@2|Bacteria,2I49A@201174|Actinobacteria,4EFBV@85010|Pseudonocardiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_2881577_0	882083.SacmaDRAFT_2390	8.914e-201	634.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4E1QA@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
TLS3_k127_2881577_4	1157632.AQWQ01000005_gene921	1.041e-102	367.0	COG1960@1|root,COG1960@2|Bacteria,2GMKM@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
TLS3_k127_2881577_3	1123024.AUII01000002_gene1153	4.083e-109	369.0	COG0477@1|root,COG0477@2|Bacteria,2IP3M@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_2890978_0	1120948.KB903217_gene1176	5.598e-131	432.0	COG0543@1|root,COG1017@1|root,COG0543@2|Bacteria,COG1017@2|Bacteria,2GKXT@201174|Actinobacteria,4DXMR@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the globin family	fhbA	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Globin,NAD_binding_1
TLS3_k127_2890978_1	2074.JNYD01000015_gene4382	2.552e-113	369.0	COG2013@1|root,COG2013@2|Bacteria,2I9XC@201174|Actinobacteria	201174|Actinobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
TLS3_k127_2890978_2	1120948.KB903217_gene1175	1.711e-60	215.0	COG0789@1|root,COG0789@2|Bacteria,2IQJ4@201174|Actinobacteria,4E3E3@85010|Pseudonocardiales	201174|Actinobacteria	K	MerR family	hspR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
TLS3_k127_2890978_3	1120948.KB903217_gene1174	2.326e-36	139.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4DYUX@85010|Pseudonocardiales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
TLS3_k127_2891024_1	1120948.KB903240_gene3790	6.128e-60	217.0	COG3266@1|root,COG3266@2|Bacteria,2GP1Z@201174|Actinobacteria,4DZQN@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM type VII secretion protein EccB, Actinobacterial	eccB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	T7SS_ESX1_EccB
TLS3_k127_2891024_2	1120948.KB903240_gene3791	2.761e-59	218.0	COG3651@1|root,COG3651@2|Bacteria,2IHNI@201174|Actinobacteria,4E64C@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2237)	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
TLS3_k127_2891024_0	1120948.KB903240_gene3792	1.641e-139	446.0	COG0215@1|root,COG0215@2|Bacteria,2GJZR@201174|Actinobacteria,4DYWB@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins	mshC	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iNJ661.Rv2130c	tRNA-synt_1e
TLS3_k127_2893470_1	1120948.KB903220_gene132	0.0006911	42.0	COG3707@1|root,COG3707@2|Bacteria,2I2Q0@201174|Actinobacteria,4E63F@85010|Pseudonocardiales	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
TLS3_k127_2893470_0	164757.Mjls_0762	1.298e-270	853.0	COG1502@1|root,COG4850@1|root,COG1502@2|Bacteria,COG4850@2|Bacteria,2GN2V@201174|Actinobacteria,2377Y@1762|Mycobacteriaceae	201174|Actinobacteria	I	PFAM phospholipase D	-	-	-	-	-	-	-	-	-	-	-	-	PLDc,PLDc_2
TLS3_k127_2896980_4	65497.JODV01000018_gene3017	1.372e-32	141.0	COG5015@1|root,COG5015@2|Bacteria,2IMRG@201174|Actinobacteria,4E49X@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
TLS3_k127_2896980_2	653045.Strvi_6193	2.858e-133	430.0	COG0702@1|root,COG0702@2|Bacteria,2GKXI@201174|Actinobacteria	201174|Actinobacteria	GM	PFAM NmrA family protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
TLS3_k127_2896980_1	653045.Strvi_6192	1.274e-155	496.0	COG2207@1|root,COG2207@2|Bacteria,2GK7Q@201174|Actinobacteria	201174|Actinobacteria	K	Arac family	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
TLS3_k127_2896980_3	1237500.ANBA01000017_gene1644	2.156e-83	279.0	COG3427@1|root,COG3427@2|Bacteria,2IKHF@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_2896980_0	1120948.KB903247_gene4595	7.783e-209	652.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4DXMC@85010|Pseudonocardiales	201174|Actinobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
TLS3_k127_2902272_11	211114.JOEF01000010_gene3387	3.622e-07	52.0	COG1028@1|root,COG1028@2|Bacteria,2GJVU@201174|Actinobacteria,4E11V@85010|Pseudonocardiales	201174|Actinobacteria	IQ	short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_2902272_1	1120948.KB903246_gene3211	4.083e-220	706.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4DYFI@85010|Pseudonocardiales	201174|Actinobacteria	S	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_2902272_7	1120948.KB903246_gene3210	7e-91	329.0	COG0612@1|root,COG0612@2|Bacteria,2GKAT@201174|Actinobacteria,4DY6R@85010|Pseudonocardiales	201174|Actinobacteria	S	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_2902272_8	1120948.KB903246_gene3210	2.431e-79	268.0	COG0612@1|root,COG0612@2|Bacteria,2GKAT@201174|Actinobacteria,4DY6R@85010|Pseudonocardiales	201174|Actinobacteria	S	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
TLS3_k127_2902272_3	1120948.KB903246_gene3209	4.576e-148	499.0	COG2816@1|root,COG2816@2|Bacteria,2GJZY@201174|Actinobacteria,4DXT4@85010|Pseudonocardiales	201174|Actinobacteria	L	NADH pyrophosphatase	nudC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
TLS3_k127_2902272_9	1120948.KB903246_gene3208	8.42e-40	156.0	COG0695@1|root,COG0695@2|Bacteria,2IQF9@201174|Actinobacteria,4E757@85010|Pseudonocardiales	201174|Actinobacteria	O	Glutaredoxin	-	-	1.20.4.3	ko:K18917	-	-	-	-	ko00000,ko01000	-	-	-	Glutaredoxin
TLS3_k127_2902272_0	1120948.KB903246_gene3207	0.0	1556.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,2GM5R@201174|Actinobacteria	201174|Actinobacteria	CE	Belongs to the aldehyde dehydrogenase family	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
TLS3_k127_2902272_5	1120948.KB903246_gene3206	3.598e-100	336.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PAS_4,Reg_prop,Y_Y_Y
TLS3_k127_2902272_6	479432.Sros_6787	6.428e-91	325.0	COG0842@1|root,COG0842@2|Bacteria,2I5GM@201174|Actinobacteria,4EJ68@85012|Streptosporangiales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
TLS3_k127_2902272_4	1120936.KB907211_gene223	1.822e-126	412.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4EI8B@85012|Streptosporangiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K18232	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC_tran,DUF4162
TLS3_k127_2902272_2	2074.JNYD01000005_gene3087	1.331e-183	582.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,4DXMZ@85010|Pseudonocardiales	201174|Actinobacteria	L	helicase	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
TLS3_k127_2903008_9	1120948.KB903218_gene2246	1.039e-09	59.0	COG0739@1|root,COG0739@2|Bacteria,2GKXN@201174|Actinobacteria,4E2QB@85010|Pseudonocardiales	201174|Actinobacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2903008_2	1120948.KB903223_gene183	1.012e-85	302.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4DZBG@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TLS3_k127_2903008_4	1120948.KB903223_gene184	1.98e-74	254.0	2ADQJ@1|root,313FX@2|Bacteria,2H0DG@201174|Actinobacteria,4E2J8@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2903008_3	1137271.AZUM01000003_gene3408	5.709e-81	280.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria,4DYX5@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigJ	GO:0000988,GO:0000990,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
TLS3_k127_2903008_6	2074.JNYD01000006_gene1792	5.269e-60	216.0	COG2128@1|root,COG2128@2|Bacteria,2I829@201174|Actinobacteria,4E36F@85010|Pseudonocardiales	201174|Actinobacteria	S	carboxymuconolactone decarboxylase	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	CMD
TLS3_k127_2903008_0	1120948.KB903243_gene2491	2.825e-219	686.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4DZSK@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K06446	ko00930,ko01100,ko01120,map00930,map01100,map01120	-	R06943	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_2903008_1	1120948.KB903218_gene2240	5.856e-173	550.0	COG0427@1|root,COG0427@2|Bacteria,2IAMG@201174|Actinobacteria,4E68T@85010|Pseudonocardiales	201174|Actinobacteria	C	Acetyl-CoA hydrolase/transferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C
TLS3_k127_2903008_7	1120948.KB903218_gene2237	6.112e-39	149.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4E5MK@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Uncharacterised BCR, COG1937	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
TLS3_k127_2903008_5	1120948.KB903217_gene1080	8.654e-66	237.0	COG2367@1|root,COG2367@2|Bacteria,2GKPU@201174|Actinobacteria,4E4MS@85010|Pseudonocardiales	201174|Actinobacteria	V	Beta-lactamase	lppW	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
TLS3_k127_2909807_6	1120948.KB903248_gene4230	1.233e-77	271.0	COG0132@1|root,COG0132@2|Bacteria,2GIZ2@201174|Actinobacteria,4E12R@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004141,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017076,GO:0017144,GO:0018130,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
TLS3_k127_2909807_0	1120948.KB903248_gene4229	3.974e-198	621.0	COG0502@1|root,COG0502@2|Bacteria,2GIUE@201174|Actinobacteria,4DXZ3@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
TLS3_k127_2909807_8	1120948.KB903248_gene4228	2.249e-18	98.0	2EH0W@1|root,33ASY@2|Bacteria,2GSW1@201174|Actinobacteria,4E6EY@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2909807_7	1120948.KB903248_gene4227	2.838e-34	143.0	2EGQJ@1|root,33AGQ@2|Bacteria,2INZ1@201174|Actinobacteria,4E40B@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2567)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2567
TLS3_k127_2909807_3	1463855.JOHV01000077_gene61	5.904e-118	390.0	COG0624@1|root,COG0624@2|Bacteria,2I8IJ@201174|Actinobacteria	201174|Actinobacteria	E	Acetylornithine deacetylase	argE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
TLS3_k127_2909807_4	1120948.KB903248_gene4226	1.349e-97	336.0	COG2802@1|root,COG2802@2|Bacteria,2GNWA@201174|Actinobacteria,4E2YN@85010|Pseudonocardiales	201174|Actinobacteria	S	Peptidase S16, lon domain protein	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
TLS3_k127_2909807_2	1120948.KB903248_gene4225	1.759e-118	384.0	COG1051@1|root,COG1051@2|Bacteria,2GNMT@201174|Actinobacteria,4E06U@85010|Pseudonocardiales	201174|Actinobacteria	F	pfam nudix	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
TLS3_k127_2909807_1	1120948.KB903248_gene4224	8.055e-176	557.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria,4DY6D@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0030312,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
TLS3_k127_2909807_5	2074.JNYD01000003_gene4065	5.24e-89	316.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4E18N@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	GO:0008150,GO:0040007	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1595	FAD_binding_2,Succ_DH_flav_C
TLS3_k127_291583_0	1150864.MILUP08_45981	9.952e-107	368.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria,4D9MG@85008|Micromonosporales	201174|Actinobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
TLS3_k127_291583_1	2002.JOEQ01000003_gene2492	4.83e-46	174.0	COG2453@1|root,COG2453@2|Bacteria,2IHXA@201174|Actinobacteria,4EJ4H@85012|Streptosporangiales	201174|Actinobacteria	T	Protein-tyrosine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase
TLS3_k127_2916034_1	1120948.KB903248_gene4359	1.541e-101	345.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,4DZTC@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
TLS3_k127_2916034_0	1120948.KB903248_gene4358	6.106e-212	675.0	COG0596@1|root,COG0596@2|Bacteria,2GJYS@201174|Actinobacteria,4DZB9@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha beta hydrolase	caeA	GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019538,GO:0030312,GO:0036211,GO:0043170,GO:0043207,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0052689,GO:0071704,GO:0071944,GO:0075136,GO:1901564	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_2916034_2	1449976.KALB_1080	2.68e-68	233.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4DXYJ@85010|Pseudonocardiales	201174|Actinobacteria	E	glutamine synthetase	glnA2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
TLS3_k127_2933756_2	1120948.KB903218_gene2218	1.835e-09	58.0	COG4114@1|root,COG4114@2|Bacteria,2HNE0@201174|Actinobacteria,4E6WT@85010|Pseudonocardiales	201174|Actinobacteria	S	FhuF 2Fe-2S C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FhuF,FhuF_C
TLS3_k127_2933756_1	1120948.KB903218_gene2219	1.529e-85	290.0	2DBXI@1|root,2ZBQ3@2|Bacteria,2GJN1@201174|Actinobacteria,4E36R@85010|Pseudonocardiales	201174|Actinobacteria	S	Peptidase M50B-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
TLS3_k127_2933756_0	1120948.KB903218_gene2220	5.384e-211	681.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DYBA@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
TLS3_k127_2933756_3	1179773.BN6_69890	1.166e-06	50.0	COG0520@1|root,COG0520@2|Bacteria,2GJA4@201174|Actinobacteria,4E0HN@85010|Pseudonocardiales	201174|Actinobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
TLS3_k127_2942136_1	1123023.JIAI01000007_gene1877	5.905e-105	352.0	COG0475@1|root,COG0475@2|Bacteria,2GJ69@201174|Actinobacteria,4DXKN@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
TLS3_k127_2942136_2	1123023.JIAI01000007_gene1878	1.243e-62	219.0	COG0490@1|root,COG0490@2|Bacteria,2IFBQ@201174|Actinobacteria,4E3CX@85010|Pseudonocardiales	201174|Actinobacteria	P	regulatory ligand binding protein, C-terminal domain of K channels like protein	-	-	-	ko:K07228	-	-	-	-	ko00000	-	-	-	TrkA_C
TLS3_k127_2942136_0	1120948.KB903246_gene3311	3.194e-178	564.0	COG2171@1|root,COG2171@2|Bacteria,2GIZ9@201174|Actinobacteria,4DYHD@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1201c	Hexapep_2,THDPS_M
TLS3_k127_2942136_3	28444.JODQ01000014_gene6934	1.449e-05	54.0	COG3619@1|root,COG3619@2|Bacteria,2I155@201174|Actinobacteria,4EKYU@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF1275)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
TLS3_k127_2955186_6	1120948.KB903247_gene4584	4.796e-11	67.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4E27Q@85010|Pseudonocardiales	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0016491,GO:0016667,GO:0016671,GO:0020012,GO:0030682,GO:0033744,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0075136	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
TLS3_k127_2955186_2	2074.JNYD01000014_gene7066	7.543e-66	231.0	COG3832@1|root,COG3832@2|Bacteria,2IHQ1@201174|Actinobacteria,4E454@85010|Pseudonocardiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_2955186_4	1120948.KB903217_gene1393	7.234e-33	134.0	COG1514@1|root,COG1514@2|Bacteria,2IKSA@201174|Actinobacteria,4E66X@85010|Pseudonocardiales	201174|Actinobacteria	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
TLS3_k127_2955186_1	253839.SSNG_02507	6.252e-66	231.0	COG2085@1|root,COG2085@2|Bacteria,2GMN3@201174|Actinobacteria	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
TLS3_k127_2955186_3	479432.Sros_3056	5.313e-48	180.0	2AXJH@1|root,31PJJ@2|Bacteria,2IQYQ@201174|Actinobacteria,4EKBM@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2955186_0	1120948.KB903225_gene5542	2.361e-67	241.0	COG3173@1|root,COG3173@2|Bacteria,2HKPJ@201174|Actinobacteria,4E2MN@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
TLS3_k127_2955186_5	543632.JOJL01000022_gene856	9.939e-13	70.0	2E5PW@1|root,330EJ@2|Bacteria,2GRTF@201174|Actinobacteria,4DGJX@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3817
TLS3_k127_2955278_0	1120948.KB903219_gene749	0.0	1159.0	COG1807@1|root,COG1807@2|Bacteria,2GKH9@201174|Actinobacteria,4E1F9@85010|Pseudonocardiales	201174|Actinobacteria	M	Mycobacterial cell wall arabinan synthesis protein	embC	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0052636,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K11386,ko:K11387	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Arabino_trans_C,Arabinose_trans
TLS3_k127_2955278_3	1120948.KB903219_gene750	4.736e-168	542.0	COG1216@1|root,COG1216@2|Bacteria,2GMQQ@201174|Actinobacteria,4DXAE@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Glycosyl transferase family 2	glfT1	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008378,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016757,GO:0016758,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.4.1.287	ko:K16649	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_2955278_5	1120948.KB903219_gene751	1.963e-140	468.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4DYMG@85010|Pseudonocardiales	201174|Actinobacteria	GM	ABC-type polysaccharide polyol phosphate transport system, ATPase component	rfbE	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran
TLS3_k127_2955278_2	1120948.KB903219_gene752	4.57e-174	558.0	COG1682@1|root,COG1682@2|Bacteria,2HIJY@201174|Actinobacteria,4DY6S@85010|Pseudonocardiales	201174|Actinobacteria	GM	ABC-type polysaccharide polyol phosphate export	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
TLS3_k127_2955278_6	1120948.KB903219_gene753	6.993e-64	238.0	291ZT@1|root,2ZPJ4@2|Bacteria,2GR7R@201174|Actinobacteria,4E2RM@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2587)	bpa	GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369	-	-	-	-	-	-	-	-	-	-	DUF2587
TLS3_k127_2955278_1	1120948.KB903219_gene754	2.633e-197	621.0	COG0520@1|root,COG0520@2|Bacteria,2GKAF@201174|Actinobacteria,4DZ2K@85010|Pseudonocardiales	201174|Actinobacteria	E	Cysteine desulfurase family protein, VC1184 subfamily	csd	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
TLS3_k127_2955278_4	1120948.KB903219_gene755	9.426e-153	489.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,4DZ5G@85010|Pseudonocardiales	201174|Actinobacteria	C	NAD(P)H quinone oxidoreductase, PIG3 family	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_2965966_12	1120948.KB903217_gene1279	1.438e-29	126.0	COG0680@1|root,COG0680@2|Bacteria,2GN48@201174|Actinobacteria,4E5CZ@85010|Pseudonocardiales	201174|Actinobacteria	C	TIGRFAM hydrogenase maturation protease	hupD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
TLS3_k127_2965966_2	1120948.KB903217_gene1278	2.254e-185	589.0	2DBQJ@1|root,2ZAF2@2|Bacteria,2I2YB@201174|Actinobacteria,4EDYQ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2965966_7	1120948.KB903217_gene1277	7.284e-83	280.0	29Z4R@1|root,30M2D@2|Bacteria,2GNPH@201174|Actinobacteria,4E463@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2965966_10	1120948.KB903217_gene1276	2.691e-67	244.0	2ADVU@1|root,313MT@2|Bacteria,2H7PH@201174|Actinobacteria,4E59S@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2965966_11	1120948.KB903217_gene1275	1.48e-52	207.0	COG0694@1|root,COG0694@2|Bacteria,2GKHD@201174|Actinobacteria,4E6ME@85010|Pseudonocardiales	201174|Actinobacteria	O	PFAM nitrogen-fixing NifU domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NifU,Rieske
TLS3_k127_2965966_0	1120948.KB903217_gene1274	0.0	1150.0	COG0374@1|root,COG0374@2|Bacteria,2GKQY@201174|Actinobacteria,4E012@85010|Pseudonocardiales	201174|Actinobacteria	C	Ni,Fe-hydrogenase I large subunit	hydB	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
TLS3_k127_2965966_1	1120948.KB903217_gene1273	2.935e-206	644.0	COG1740@1|root,COG1740@2|Bacteria,2GKF2@201174|Actinobacteria,4DY4Z@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
TLS3_k127_2965966_6	2074.JNYD01000007_gene1986	7.381e-116	378.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria,4E3H9@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
TLS3_k127_2965966_3	1123023.JIAI01000009_gene950	2.237e-175	559.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4E3CF@85010|Pseudonocardiales	201174|Actinobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_2965966_9	1120948.KB903240_gene3960	1.115e-74	273.0	COG1522@1|root,COG1522@2|Bacteria,2H359@201174|Actinobacteria,4EB74@85010|Pseudonocardiales	201174|Actinobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
TLS3_k127_2965966_8	526225.Gobs_2327	1.275e-82	285.0	COG0252@1|root,COG0252@2|Bacteria,2HUB2@201174|Actinobacteria	201174|Actinobacteria	EJ	asparaginase	ansA	GO:0003674,GO:0003824,GO:0004067,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032787,GO:0034641,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
TLS3_k127_2965966_4	1445613.JALM01000001_gene3178	7.386e-174	548.0	COG0726@1|root,COG0726@2|Bacteria,2GM0X@201174|Actinobacteria,4E266@85010|Pseudonocardiales	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
TLS3_k127_2965966_5	1120948.KB903240_gene3959	1.386e-122	401.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4DYAB@85010|Pseudonocardiales	201174|Actinobacteria	L	ATPase family associated with various cellular activities (AAA)	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
TLS3_k127_2974287_5	1828.JOKB01000001_gene109	3.524e-90	302.0	COG0745@1|root,COG0745@2|Bacteria,2GNFH@201174|Actinobacteria,4FW3F@85025|Nocardiaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	prrA	GO:0000287,GO:0003674,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043167,GO:0043169,GO:0044110,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051704,GO:0071944	-	ko:K07671	ko02020,map02020	M00462	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_2974287_14	1122609.AUGT01000001_gene2837	2e-22	107.0	COG0500@1|root,COG2226@2|Bacteria,2GUHW@201174|Actinobacteria,4DS9J@85009|Propionibacteriales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_2974287_4	1120948.KB903240_gene4127	1.279e-108	358.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria,4DYVB@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Enoyl-CoA hydratase isomerase	echA3	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
TLS3_k127_2974287_17	1283283.ATXA01000019_gene2908	1.219e-10	64.0	COG2267@1|root,COG2267@2|Bacteria,2HM71@201174|Actinobacteria	201174|Actinobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
TLS3_k127_2974287_0	1120948.KB903243_gene2613	2.987e-222	705.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZWD@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_2974287_6	1120948.KB903243_gene2614	2.954e-77	272.0	COG1309@1|root,COG1309@2|Bacteria,2GJZJ@201174|Actinobacteria,4DZRZ@85010|Pseudonocardiales	201174|Actinobacteria	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_2974287_10	290340.AAur_3847	3.746e-42	164.0	COG0454@1|root,COG0456@2|Bacteria,2IFM6@201174|Actinobacteria,1WA6H@1268|Micrococcaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Condensation
TLS3_k127_2974287_7	1123024.AUII01000009_gene2000	6.058e-73	252.0	COG0586@1|root,COG1132@1|root,COG0586@2|Bacteria,COG1132@2|Bacteria,2GKKC@201174|Actinobacteria,4E2BV@85010|Pseudonocardiales	201174|Actinobacteria	V	SNARE associated Golgi protein	dedA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
TLS3_k127_2974287_16	1288079.AUKN01000005_gene5155	1.288e-14	85.0	2CFK1@1|root,334PB@2|Bacteria,2GQPZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2974287_1	28444.JODQ01000005_gene1332	3.989e-203	637.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4EGIK@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_2974287_8	1449346.JQMO01000003_gene2685	1.463e-71	247.0	COG1309@1|root,COG1309@2|Bacteria,2ID86@201174|Actinobacteria,2M1J5@2063|Kitasatospora	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_2974287_2	749927.AMED_4776	3.342e-182	609.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4E0IZ@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,TPR_12,Trans_reg_C
TLS3_k127_2974287_9	1242864.D187_000036	6.059e-65	232.0	COG2267@1|root,COG2267@2|Bacteria,1R08U@1224|Proteobacteria,42XGE@68525|delta/epsilon subdivisions,2X8N8@28221|Deltaproteobacteria,2Z36G@29|Myxococcales	28221|Deltaproteobacteria	I	Pfam:DUF2305	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_2974287_13	1123023.JIAI01000011_gene8847	1.257e-28	127.0	COG0265@1|root,COG0265@2|Bacteria,2GJJ3@201174|Actinobacteria,4E882@85010|Pseudonocardiales	201174|Actinobacteria	O	PDZ domain (Also known as DHR or GLGF)	pepA	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
TLS3_k127_2974287_12	1172181.KB911699_gene1622	2.467e-35	146.0	COG3795@1|root,COG3795@2|Bacteria,2IKRD@201174|Actinobacteria	201174|Actinobacteria	S	PFAM YCII-related	-	-	-	-	-	-	-	-	-	-	-	-	YCII
TLS3_k127_2974287_3	227882.SAV_1195	1.238e-155	524.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_2974287_11	1120948.KB903229_gene4936	1.007e-41	169.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707
TLS3_k127_297937_1	1120948.KB903240_gene3976	1.085e-83	280.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4E01I@85010|Pseudonocardiales	201174|Actinobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
TLS3_k127_297937_0	1123024.AUII01000004_gene1713	1.05e-150	485.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4DYUZ@85010|Pseudonocardiales	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	LGT
TLS3_k127_297937_2	1120948.KB903240_gene3974	2.575e-72	255.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,2GN09@201174|Actinobacteria,4DX9H@85010|Pseudonocardiales	201174|Actinobacteria	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
TLS3_k127_2987338_2	1120948.KB903217_gene1002	2.538e-114	398.0	COG3170@1|root,COG3170@2|Bacteria,2GN00@201174|Actinobacteria,4DZT3@85010|Pseudonocardiales	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2987338_4	1120948.KB903217_gene1003	2.804e-62	239.0	COG1051@1|root,COG1051@2|Bacteria,2I2DG@201174|Actinobacteria,4E30H@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_2987338_0	1120948.KB903217_gene1004	9.263e-273	845.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria,4DY9Z@85010|Pseudonocardiales	201174|Actinobacteria	J	Poly A polymerase, head domain	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
TLS3_k127_2987338_5	1206735.BAGG01000124_gene5470	3.682e-20	104.0	2DEVA@1|root,2ZPDC@2|Bacteria,2GRS3@201174|Actinobacteria,4G9R2@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_2987338_1	1120948.KB903217_gene1005	2.508e-175	566.0	COG0477@1|root,COG2814@2|Bacteria,2I3P4@201174|Actinobacteria,4E051@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_2987338_3	1120948.KB903217_gene1006	1.648e-100	334.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria,4DZ3Q@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the UPF0301 (AlgH) family	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
TLS3_k127_2987338_6	1120948.KB903217_gene1007	1.747e-09	67.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria	201174|Actinobacteria	IQ	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
TLS3_k127_3003571_2	1120948.KB903246_gene3187	1.349e-92	308.0	COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,4DZMR@85010|Pseudonocardiales	201174|Actinobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TLS3_k127_3003571_0	1068978.AMETH_5280	1.269e-194	616.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4E0QH@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_3003571_1	40571.JOEA01000012_gene1036	7.167e-132	427.0	COG0480@1|root,COG0480@2|Bacteria,2GKRU@201174|Actinobacteria,4DYQ5@85010|Pseudonocardiales	201174|Actinobacteria	J	elongation factor G domain IV	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
TLS3_k127_3028677_1	1120948.KB903240_gene4038	1.027e-217	685.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4DX4Z@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
TLS3_k127_3028677_3	1120948.KB903240_gene4037	5.493e-33	134.0	2DEAM@1|root,32U30@2|Bacteria,2IQPT@201174|Actinobacteria,4E6RS@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3028677_2	1120948.KB903240_gene4018	1.145e-109	399.0	COG1277@1|root,COG1277@2|Bacteria,2GP6D@201174|Actinobacteria,4DZEX@85010|Pseudonocardiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
TLS3_k127_3028677_0	1120948.KB903240_gene4017	0.0	1136.0	COG1131@1|root,COG2936@1|root,COG1131@2|Bacteria,COG2936@2|Bacteria,2GN8P@201174|Actinobacteria,4DZ82@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,PepX_C,Peptidase_S15
TLS3_k127_3028677_4	43354.JOIJ01000015_gene1234	1.015e-22	102.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4DYPS@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
TLS3_k127_3034953_2	1120948.KB903217_gene1179	4.515e-78	270.0	2DEM0@1|root,2ZNE6@2|Bacteria,2GMFR@201174|Actinobacteria,4DY0N@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3034953_0	1120948.KB903217_gene1178	7.961e-241	771.0	COG0488@1|root,COG0488@2|Bacteria,2GK9S@201174|Actinobacteria,4DXD2@85010|Pseudonocardiales	201174|Actinobacteria	S	ATPases associated with a variety of cellular activities	yjjK	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
TLS3_k127_3034953_3	1211815.CBYP010000050_gene640	1.941e-68	244.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria,4EUCV@85013|Frankiales	201174|Actinobacteria	T	integral membrane sensor signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_3034953_1	749927.AMED_4776	1.829e-111	387.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4E0IZ@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,TPR_12,Trans_reg_C
TLS3_k127_3081331_1	1120948.KB903217_gene1493	4.421e-70	239.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4DX8D@85010|Pseudonocardiales	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_3081331_0	1120948.KB903217_gene1492	8.701e-101	342.0	COG0300@1|root,COG0300@2|Bacteria,2GNPI@201174|Actinobacteria,4EF8W@85010|Pseudonocardiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.333	ko:K16652	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
TLS3_k127_3081331_7	1120948.KB903217_gene1491	5.18e-24	111.0	COG0347@1|root,COG0347@2|Bacteria	2|Bacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
TLS3_k127_3081331_2	219305.MCAG_05073	7.647e-64	235.0	COG2172@1|root,COG2172@2|Bacteria,2GKU6@201174|Actinobacteria,4DBFR@85008|Micromonosporales	201174|Actinobacteria	T	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	prsR	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MEDS
TLS3_k127_3081331_3	1206729.BAFZ01000036_gene4845	4.521e-63	223.0	2AEJC@1|root,314EV@2|Bacteria,2GMTI@201174|Actinobacteria,4G1SG@85025|Nocardiaceae	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
TLS3_k127_3081331_8	2074.JNYD01000015_gene4383	1.4e-12	79.0	COG5485@1|root,COG5485@2|Bacteria,2HPCE@201174|Actinobacteria,4E7T2@85010|Pseudonocardiales	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
TLS3_k127_3081331_4	1283283.ATXA01000006_gene1767	2.233e-60	224.0	2DKWS@1|root,30N64@2|Bacteria,2IQR3@201174|Actinobacteria,4ETMN@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4188
TLS3_k127_3081331_5	35754.JNYJ01000043_gene4508	3.528e-46	177.0	COG5592@1|root,COG5592@2|Bacteria	2|Bacteria	I	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
TLS3_k127_3081331_6	1157637.KB892101_gene2472	1.199e-33	133.0	COG1733@1|root,COG1733@2|Bacteria,2GSNS@201174|Actinobacteria	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
TLS3_k127_3081331_9	1120948.KB903217_gene1490	9.606e-09	65.0	COG1666@1|root,COG1666@2|Bacteria,2IFIU@201174|Actinobacteria,4E191@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the UPF0234 family	trpF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
TLS3_k127_3116883_8	1179773.BN6_00390	2.982e-30	130.0	COG0300@1|root,COG0300@2|Bacteria,2GJ1R@201174|Actinobacteria,4E1JN@85010|Pseudonocardiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_3116883_7	1996.JOFO01000015_gene1048	4.012e-57	218.0	COG0654@1|root,COG0654@2|Bacteria,2GN2W@201174|Actinobacteria,4EH4C@85012|Streptosporangiales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
TLS3_k127_3116883_9	471852.Tcur_2696	2.098e-24	110.0	COG1309@1|root,COG1309@2|Bacteria,2H11Y@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_3116883_3	1120948.KB903219_gene762	5.51e-86	304.0	COG4762@1|root,COG4762@2|Bacteria,2IBA0@201174|Actinobacteria,4E4B3@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF1990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1990
TLS3_k127_3116883_6	1298880.AUEV01000013_gene4001	1.379e-57	219.0	COG0702@1|root,COG0702@2|Bacteria,2IA0W@201174|Actinobacteria	201174|Actinobacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1990
TLS3_k127_3116883_4	1463825.JNXC01000038_gene3321	4.086e-77	277.0	COG1835@1|root,COG1835@2|Bacteria,2HJUY@201174|Actinobacteria,4E1EC@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS3_k127_3116883_1	1120948.KB903219_gene764	1.945e-146	476.0	COG0079@1|root,COG0079@2|Bacteria,2GJXS@201174|Actinobacteria,4DX5Y@85010|Pseudonocardiales	201174|Actinobacteria	E	May catalyze the transamination reaction in phenylalanine biosynthesis	pat	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_3116883_2	1120948.KB903219_gene765	9.93e-95	318.0	COG0412@1|root,COG0412@2|Bacteria,2I947@201174|Actinobacteria,4E2FF@85010|Pseudonocardiales	201174|Actinobacteria	Q	dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
TLS3_k127_3116883_0	1120948.KB903219_gene766	2.242e-265	827.0	COG2898@1|root,COG2898@2|Bacteria,2I2ZR@201174|Actinobacteria,4EF7Y@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3,6.1.1.6	ko:K04567,ko:K14205	ko00970,ko01503,ko02020,ko05150,map00970,map01503,map02020,map05150	M00359,M00360,M00726	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko01504,ko03016	2.A.1.3.37	-	-	DUF2156,tRNA-synt_2_TM
TLS3_k127_3116883_5	1120948.KB903219_gene767	1.225e-61	213.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4DXJ5@85010|Pseudonocardiales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	adh	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
TLS3_k127_3150292_2	1449976.KALB_2735	1.51e-19	88.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,2IH0Y@201174|Actinobacteria,4E30J@85010|Pseudonocardiales	201174|Actinobacteria	FL	Metal binding domain of Ada	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1
TLS3_k127_3150292_4	234621.RER_50970	2.413e-09	61.0	COG1028@1|root,COG1028@2|Bacteria,2GJ9X@201174|Actinobacteria,4FYMB@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
TLS3_k127_3150292_3	1122247.C731_3105	8.511e-18	89.0	COG1028@1|root,COG1028@2|Bacteria,2GJ9X@201174|Actinobacteria,232R4@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_3150292_1	1120948.KB903223_gene180	3.2e-96	323.0	COG3358@1|root,COG3358@2|Bacteria,2GK08@201174|Actinobacteria,4E0T1@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
TLS3_k127_3150292_0	1120948.KB903247_gene4584	5.623e-97	318.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4E27Q@85010|Pseudonocardiales	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0016491,GO:0016667,GO:0016671,GO:0020012,GO:0030682,GO:0033744,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0075136	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
TLS3_k127_3157089_1	1120948.KB903248_gene4286	5.688e-60	211.0	COG2227@1|root,COG2227@2|Bacteria,2GMAR@201174|Actinobacteria,4E0YQ@85010|Pseudonocardiales	201174|Actinobacteria	H	Methyltransferase	smtA	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
TLS3_k127_3157089_0	1449976.KALB_7143	3.593e-134	448.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4DXRB@85010|Pseudonocardiales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
TLS3_k127_3157089_2	1120948.KB903248_gene4285	3.852e-18	86.0	2E49S@1|root,32Z5G@2|Bacteria,2IHN1@201174|Actinobacteria,4E4CA@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3040
TLS3_k127_3178448_2	1120948.KB903217_gene931	3.591e-82	280.0	COG3663@1|root,COG3663@2|Bacteria,2GNS5@201174|Actinobacteria,4E3MK@85010|Pseudonocardiales	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
TLS3_k127_3178448_1	1120948.KB903217_gene942	4.635e-138	461.0	COG0604@1|root,COG0604@2|Bacteria,2HHQ9@201174|Actinobacteria,4E0IK@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_3178448_0	1120948.KB903217_gene944	4.27e-156	523.0	COG2303@1|root,COG2303@2|Bacteria,2GJ3J@201174|Actinobacteria,4DYHW@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the oxidation and isomerization of cholesterol to cholestenone (4-cholesten-3-one), which is an initial step in the cholesterol degradation process. Required for virulence	choD	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_binding_2,GMC_oxred_C,GMC_oxred_N
TLS3_k127_3194619_1	1120948.KB903225_gene5516	5.266e-106	359.0	COG0745@1|root,COG0745@2|Bacteria,2GMZK@201174|Actinobacteria,4E1E0@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_3194619_0	1120948.KB903225_gene5517	1.404e-109	381.0	COG0642@1|root,COG2205@2|Bacteria,2I2QY@201174|Actinobacteria,4E07F@85010|Pseudonocardiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_3194619_2	1121861.KB899910_gene678	2.242e-05	48.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2U450@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG0631 Serine threonine protein phosphatase	-	-	3.1.3.16	ko:K11915	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko02044	-	-	-	PP2C_2
TLS3_k127_3216590_7	591158.SSMG_02288	0.0001912	48.0	COG1314@1|root,COG1314@2|Bacteria,2GR31@201174|Actinobacteria	201174|Actinobacteria	U	Preprotein translocase SecG subunit	secG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
TLS3_k127_3216590_5	1120948.KB903240_gene3906	1.989e-133	431.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4DZ67@85010|Pseudonocardiales	201174|Actinobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
TLS3_k127_3216590_0	1120948.KB903240_gene3907	1.08e-208	656.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4DX3T@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
TLS3_k127_3216590_2	1120948.KB903240_gene3908	3.317e-181	600.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4DYE3@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
TLS3_k127_3216590_3	1123023.JIAI01000003_gene2616	1.508e-159	515.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4DZ5U@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_3216590_1	1120948.KB903240_gene3909	3.086e-186	585.0	COG1481@1|root,COG1481@2|Bacteria,2GJZU@201174|Actinobacteria,4E12N@85010|Pseudonocardiales	201174|Actinobacteria	K	May be required for sporulation	whiA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
TLS3_k127_3216590_6	103733.JNYO01000026_gene8857	2.529e-114	392.0	COG0391@1|root,COG0391@2|Bacteria,2GJBW@201174|Actinobacteria,4DZS2@85010|Pseudonocardiales	201174|Actinobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
TLS3_k127_3216590_4	1120948.KB903240_gene3911	4.822e-154	490.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4DXU0@85010|Pseudonocardiales	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
TLS3_k127_3220724_4	471857.Svir_19070	3.644e-70	241.0	COG3327@1|root,COG3327@2|Bacteria,2GNME@201174|Actinobacteria,4DXAA@85010|Pseudonocardiales	201174|Actinobacteria	K	Phenylacetic acid-responsive transcriptional repressor	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
TLS3_k127_3220724_1	2074.JNYD01000026_gene657	8.279e-201	633.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4E03W@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K08172	-	-	-	-	ko00000,ko02000	2.A.1.6.6	-	-	MFS_1,Sugar_tr
TLS3_k127_3220724_0	1194972.MVAC_28039	3.766e-203	645.0	COG0833@1|root,COG0833@2|Bacteria,2GM7U@201174|Actinobacteria,236MF@1762|Mycobacteriaceae	201174|Actinobacteria	E	amino acid	eutP	-	-	ko:K16238	-	-	-	-	ko00000,ko02000	2.A.3.5	-	-	AA_permease_2
TLS3_k127_3220724_2	1121033.AUCF01000021_gene2827	6.472e-187	617.0	COG4303@1|root,COG4303@2|Bacteria,1MUR4@1224|Proteobacteria,2TTNA@28211|Alphaproteobacteria,2JPSE@204441|Rhodospirillales	204441|Rhodospirillales	E	Ethanolamine ammonia-lyase large subunit	eutB	-	4.3.1.7	ko:K03735	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutB
TLS3_k127_3220724_3	477641.MODMU_3992	1.831e-87	295.0	COG4302@1|root,COG4302@2|Bacteria,2IB7Y@201174|Actinobacteria,4EV6A@85013|Frankiales	201174|Actinobacteria	E	Belongs to the EutC family	eutC	-	4.3.1.7	ko:K03736	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutC
TLS3_k127_3220724_5	675635.Psed_5102	2.023e-12	79.0	2DCBN@1|root,2ZDJP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3228375_1	1120948.KB903227_gene4836	1.405e-111	368.0	COG0668@1|root,COG0668@2|Bacteria,2HD92@201174|Actinobacteria,4E0HQ@85010|Pseudonocardiales	201174|Actinobacteria	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
TLS3_k127_3228375_0	1120948.KB903227_gene4880	1.635e-128	439.0	COG0438@1|root,COG0438@2|Bacteria,2IEDZ@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
TLS3_k127_3228375_4	1120948.KB903245_gene3566	3.712e-77	281.0	COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,4E7V8@85010|Pseudonocardiales	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_3228375_3	1120948.KB903240_gene3997	4.743e-88	312.0	COG0431@1|root,COG0431@2|Bacteria,2GNFR@201174|Actinobacteria,4E3XA@85010|Pseudonocardiales	201174|Actinobacteria	K	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
TLS3_k127_3228375_5	1120948.KB903229_gene5301	3.328e-29	118.0	2FC7K@1|root,344BD@2|Bacteria,2GSJQ@201174|Actinobacteria,4E6N4@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3228375_6	1123023.JIAI01000010_gene8689	1.315e-18	101.0	COG0642@1|root,COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria,4DY1K@85010|Pseudonocardiales	201174|Actinobacteria	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA,PAS,PAS_4,PAS_9,Response_reg,RsbU_N,SpoIIE
TLS3_k127_3228375_2	1120948.KB903227_gene4859	1.166e-103	355.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2GKUC@201174|Actinobacteria,4DZHM@85010|Pseudonocardiales	201174|Actinobacteria	KT	Stage II sporulation protein E (SpoIIE)	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,PAS,PAS_4,PAS_9,SpoIIE
TLS3_k127_3229772_2	1120948.KB903245_gene3619	1.826e-74	276.0	COG4987@1|root,COG4988@1|root,COG4987@2|Bacteria,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria,4DY1E@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD	cydD	-	-	ko:K16013,ko:K16014	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
TLS3_k127_3229772_0	1120948.KB903245_gene3620	1.813e-113	377.0	COG1294@1|root,COG1294@2|Bacteria,2GMFV@201174|Actinobacteria,4DZHN@85010|Pseudonocardiales	201174|Actinobacteria	C	TIGRFAM cytochrome d oxidase, subunit II (cydB)	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
TLS3_k127_3229772_1	1120948.KB903245_gene3621	2.403e-94	315.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4DZRD@85010|Pseudonocardiales	201174|Actinobacteria	C	Cytochrome bd-type quinol oxidase, subunit 1	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
TLS3_k127_3230462_3	1120948.KB903229_gene4975	5.276e-175	552.0	COG0753@1|root,COG0753@2|Bacteria,2GITN@201174|Actinobacteria,4DYZI@85010|Pseudonocardiales	201174|Actinobacteria	P	Serves to protect cells from the toxic effects of hydrogen peroxide	katA	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
TLS3_k127_3230462_6	1120948.KB903229_gene4976	3.778e-68	240.0	COG0783@1|root,COG0783@2|Bacteria,2IFDP@201174|Actinobacteria,4E3P7@85010|Pseudonocardiales	201174|Actinobacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
TLS3_k127_3230462_1	1120948.KB903229_gene4980	0.0	1034.0	COG1506@1|root,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4DZST@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Prolyl oligopeptidase family	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S9
TLS3_k127_3230462_7	1179773.BN6_75740	2.678e-43	183.0	COG3315@1|root,COG3315@2|Bacteria,2GNTD@201174|Actinobacteria,4E2IU@85010|Pseudonocardiales	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
TLS3_k127_3230462_5	1120948.KB903229_gene4984	1.827e-96	328.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria,4E438@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
TLS3_k127_3230462_2	1120948.KB903229_gene4985	1.884e-257	800.0	COG0204@1|root,COG0560@1|root,COG0204@2|Bacteria,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria,4DX5I@85010|Pseudonocardiales	201174|Actinobacteria	E	TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490	-	-	-	-	-	-	-	-	-	-	-	-	HAD
TLS3_k127_3230462_0	1120948.KB903229_gene4986	0.0	1140.0	COG2937@1|root,COG2937@2|Bacteria,2GMQF@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the GPAT DAPAT family	plsB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TLS3_k127_3230462_4	1120948.KB903229_gene4988	1.228e-115	394.0	COG3979@1|root,COG3979@2|Bacteria,2I2XD@201174|Actinobacteria,4E1KC@85010|Pseudonocardiales	201174|Actinobacteria	S	chitinase	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
TLS3_k127_329152_0	2074.JNYD01000004_gene4902	4.271e-122	421.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DXC3@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_12,Trans_reg_C
TLS3_k127_3295505_1	882082.SaccyDRAFT_0656	6.587e-34	140.0	COG4758@1|root,COG4758@2|Bacteria,2I8FE@201174|Actinobacteria,4E31D@85010|Pseudonocardiales	201174|Actinobacteria	S	Cell wall-active antibiotics response 4TMS YvqF	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
TLS3_k127_3295505_0	1157640.AQWO01000011_gene3245	2.689e-171	552.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria	201174|Actinobacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
TLS3_k127_3295505_3	68219.JNXI01000021_gene3658	7.101e-08	63.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria	201174|Actinobacteria	H	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
TLS3_k127_3295505_2	266940.Krad_4170	4.145e-29	126.0	COG1388@1|root,COG1388@2|Bacteria,2GQ1M@201174|Actinobacteria	201174|Actinobacteria	M	Transglycosylase-like domain	rpfA	-	-	ko:K21687,ko:K21691	-	-	-	-	ko00000	-	GH23	-	DUF3235,LysM,NLPC_P60,Transglycosylas
TLS3_k127_3323614_4	1120948.KB903220_gene122	5.757e-30	135.0	COG2114@1|root,COG2114@2|Bacteria,2IKBQ@201174|Actinobacteria	201174|Actinobacteria	T	Adenylate cyclase regulatory domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Ad_Cy_reg,Guanylate_cyc
TLS3_k127_3323614_0	1120948.KB903220_gene123	5.014e-131	427.0	COG1409@1|root,COG1409@2|Bacteria,2GKMR@201174|Actinobacteria,4DZSP@85010|Pseudonocardiales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07498	-	-	-	-	ko00000	-	-	-	Metallophos
TLS3_k127_3323614_2	1120948.KB903220_gene124	1.115e-74	273.0	COG2977@1|root,COG2977@2|Bacteria,2IIA2@201174|Actinobacteria,4E2VW@85010|Pseudonocardiales	201174|Actinobacteria	Q	4'-phosphopantetheinyl transferase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ACPS
TLS3_k127_3323614_3	2074.JNYD01000017_gene4319	4.927e-37	158.0	2DM0Y@1|root,318KY@2|Bacteria,2IMIX@201174|Actinobacteria,4E63M@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF1992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1992
TLS3_k127_3323614_1	1120948.KB903220_gene125	3.256e-96	333.0	COG0419@1|root,COG0419@2|Bacteria,2HU66@201174|Actinobacteria	201174|Actinobacteria	L	DNA repair	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_23,AAA_27
TLS3_k127_3354689_0	208439.AJAP_15785	0.0	1239.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4DXI1@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
TLS3_k127_3354689_1	994479.GL877881_gene6628	6.217e-78	267.0	COG2080@1|root,COG2080@2|Bacteria,2GMYH@201174|Actinobacteria,4E4KI@85010|Pseudonocardiales	201174|Actinobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
TLS3_k127_3354689_2	1068978.AMETH_3944	5.635e-72	265.0	COG3427@1|root,COG3427@2|Bacteria,2IBJB@201174|Actinobacteria,4E4WB@85010|Pseudonocardiales	201174|Actinobacteria	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
TLS3_k127_3362845_1	1068980.ARVW01000001_gene4006	4.657e-111	393.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,4DZ8W@85010|Pseudonocardiales	201174|Actinobacteria	KLT	PFAM Protein kinase domain	pknJ	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TLS3_k127_3362845_0	1120948.KB903224_gene342	2.952e-166	550.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4DXU7@85010|Pseudonocardiales	201174|Actinobacteria	H	TIGRFAM molybdenum cofactor synthesis domain	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
TLS3_k127_3362845_2	1120948.KB903224_gene343	3.415e-98	326.0	COG0688@1|root,COG0688@2|Bacteria,2GMMF@201174|Actinobacteria,4DZG8@85010|Pseudonocardiales	201174|Actinobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
TLS3_k127_3362845_3	1120948.KB903224_gene344	1.432e-31	138.0	COG1183@1|root,COG1183@2|Bacteria,2I3MV@201174|Actinobacteria,4DXQ0@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	GO:0003674,GO:0003824,GO:0003882,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_tran_2,CDP-OH_P_transf
TLS3_k127_3374865_1	1123023.JIAI01000016_gene3388	3.291e-54	192.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4E27V@85010|Pseudonocardiales	201174|Actinobacteria	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
TLS3_k127_3374865_2	390989.JOEG01000014_gene3045	7.558e-28	116.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4DAN1@85008|Micromonosporales	201174|Actinobacteria	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
TLS3_k127_3374865_0	1120948.KB903240_gene4038	1.41e-132	425.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4DX4Z@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
TLS3_k127_3390341_0	469383.Cwoe_3372	2.451e-147	488.0	COG1330@1|root,COG1330@2|Bacteria,2GNVB@201174|Actinobacteria	201174|Actinobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
TLS3_k127_3405167_2	330084.JNYZ01000003_gene2081	5.622e-49	186.0	COG2203@1|root,COG2203@2|Bacteria,2IQAM@201174|Actinobacteria,4E5MD@85010|Pseudonocardiales	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF,GAF_2
TLS3_k127_3405167_1	1449068.JMLQ01000008_gene4109	6.408e-58	216.0	COG0265@1|root,COG0265@2|Bacteria,2GJ92@201174|Actinobacteria,4FU76@85025|Nocardiaceae	201174|Actinobacteria	O	Colicin V production protein	cvpA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
TLS3_k127_3405167_0	1120950.KB892741_gene2628	3.462e-75	263.0	COG2267@1|root,COG2267@2|Bacteria,2H83P@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the peptidase S33 family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
TLS3_k127_3435157_4	1179773.BN6_00600	8.711e-12	66.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,4DXCQ@85010|Pseudonocardiales	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TLS3_k127_3435157_0	405948.SACE_3893	4.559e-132	442.0	COG3182@1|root,COG3182@2|Bacteria,2GMHE@201174|Actinobacteria,4DZ7V@85010|Pseudonocardiales	201174|Actinobacteria	S	PepSY-associated TM region	-	-	-	-	-	-	-	-	-	-	-	-	PepSY,PepSY_TM
TLS3_k127_3435157_2	1120948.KB903243_gene2464	6.148e-45	169.0	COG4243@1|root,COG4243@2|Bacteria,2GMVK@201174|Actinobacteria,4E428@85010|Pseudonocardiales	201174|Actinobacteria	S	Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
TLS3_k127_3435157_1	1120948.KB903243_gene2631	7.094e-63	228.0	COG1131@1|root,COG1131@2|Bacteria,2HCMG@201174|Actinobacteria	201174|Actinobacteria	V	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3444103_0	1120948.KB903243_gene2302	1.184e-183	579.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4DXPC@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE25	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_3444103_1	526225.Gobs_2386	1.039e-176	563.0	COG0654@1|root,COG0654@2|Bacteria,2GXK6@201174|Actinobacteria,4ETQ0@85013|Frankiales	201174|Actinobacteria	CH	PFAM monooxygenase FAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
TLS3_k127_3444103_4	356851.JOAN01000010_gene4706	2.256e-47	177.0	COG1309@1|root,COG1309@2|Bacteria,2GP92@201174|Actinobacteria,4DB3G@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_3444103_3	1120948.KB903243_gene2303	2.769e-71	246.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4E2MB@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0008150,GO:0040007	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3275c	AIRC
TLS3_k127_3444103_2	1120948.KB903243_gene2304	7.582e-153	488.0	COG0026@1|root,COG0026@2|Bacteria,2GJCU@201174|Actinobacteria,4DXPI@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
TLS3_k127_3444753_2	675635.Psed_4207	1.543e-135	437.0	COG2146@1|root,COG2146@2|Bacteria,2I1BQ@201174|Actinobacteria,4EEXP@85010|Pseudonocardiales	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231,Rieske
TLS3_k127_3444753_5	675635.Psed_4208	1.076e-59	223.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	hcaC	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
TLS3_k127_3444753_10	1120948.KB903218_gene2134	2.09e-21	107.0	2F0SE@1|root,33TUI@2|Bacteria,2H4K4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3444753_11	1120948.KB903218_gene2134	5.143e-12	71.0	2F0SE@1|root,33TUI@2|Bacteria,2H4K4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3444753_7	929712.KI912613_gene3201	1.329e-36	156.0	COG3011@1|root,COG3011@2|Bacteria,2ID7Q@201174|Actinobacteria	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3444753_0	1120948.KB903244_gene2846	7.72e-188	590.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4DY4T@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA primase, small subunit	ligD	-	-	-	-	-	-	-	-	-	-	-	DNA_primase_S
TLS3_k127_3444753_6	1120948.KB903243_gene2665	1.257e-48	179.0	COG1846@1|root,COG1846@2|Bacteria,2IMA9@201174|Actinobacteria,4E4H2@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR
TLS3_k127_3444753_9	1120948.KB903244_gene2847	1.268e-28	120.0	2F8GV@1|root,340VP@2|Bacteria,2GTYC@201174|Actinobacteria,4E6HZ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3444753_4	1120948.KB903244_gene2848	3.748e-81	271.0	COG0229@1|root,COG0229@2|Bacteria,2IHV0@201174|Actinobacteria,4E3PU@85010|Pseudonocardiales	201174|Actinobacteria	O	Peptide-methionine (R)-S-oxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
TLS3_k127_3444753_13	266940.Krad_1505	4.443e-07	56.0	COG4126@1|root,COG4126@2|Bacteria,2IFSR@201174|Actinobacteria	201174|Actinobacteria	E	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Glu_race
TLS3_k127_3444753_3	1120948.KB903244_gene2850	4.395e-128	411.0	COG3253@1|root,COG3253@2|Bacteria,2GK24@201174|Actinobacteria,4DZFU@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Chlorite dismutase	cld	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
TLS3_k127_3444753_1	1123024.AUII01000003_gene3612	3.558e-165	536.0	COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria,4DYEJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
TLS3_k127_3444753_8	103733.JNYO01000027_gene2416	5.25e-31	124.0	COG1232@1|root,COG1232@2|Bacteria,2GMMA@201174|Actinobacteria,4E014@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
TLS3_k127_3452851_1	1120948.KB903228_gene4811	1.329e-76	270.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4DXCK@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_3452851_0	1120948.KB903228_gene4812	2.078e-157	504.0	COG0438@1|root,COG0438@2|Bacteria,2GJUN@201174|Actinobacteria,4DYRA@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
TLS3_k127_3452851_2	1120948.KB903228_gene4813	3.078e-53	190.0	COG0859@1|root,COG0859@2|Bacteria,2GSTW@201174|Actinobacteria,4DYGA@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,Hydrolase_like
TLS3_k127_3483326_5	2074.JNYD01000029_gene7217	3.041e-07	61.0	COG0642@1|root,COG0745@1|root,COG2172@1|root,COG2203@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2172@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria,4DY1K@85010|Pseudonocardiales	201174|Actinobacteria	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HATPase_c_2,HisKA,PAS_3,PAS_4,Response_reg,STAS_2,SpoIIE
TLS3_k127_3483326_3	1120948.KB903218_gene1841	4.916e-94	330.0	COG2141@1|root,COG2141@2|Bacteria,2ICP1@201174|Actinobacteria,4EEK6@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_3483326_1	1120948.KB903218_gene1842	3.285e-105	351.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4E2MM@85010|Pseudonocardiales	201174|Actinobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
TLS3_k127_3483326_4	1120948.KB903218_gene1843	9.908e-64	245.0	COG2030@1|root,COG2030@2|Bacteria,2IK9K@201174|Actinobacteria,4EB10@85010|Pseudonocardiales	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
TLS3_k127_3483326_0	675635.Psed_4795	9.116e-305	955.0	COG0365@1|root,COG0365@2|Bacteria,2IDBD@201174|Actinobacteria,4EA4F@85010|Pseudonocardiales	201174|Actinobacteria	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
TLS3_k127_3483326_2	1120948.KB903218_gene1845	2.426e-97	320.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4DZT6@85010|Pseudonocardiales	201174|Actinobacteria	I	Carboxyl transferase domain	yngE	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
TLS3_k127_3495961_2	211114.JOEF01000002_gene4458	3.295e-80	273.0	28M3Q@1|root,2ZAHT@2|Bacteria,2GM5B@201174|Actinobacteria,4E09Q@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3495961_1	1120948.KB903246_gene3377	5.436e-105	346.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4DYPN@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM channel protein, hemolysin III family	hlyI	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
TLS3_k127_3495961_0	1120948.KB903246_gene3376	2.278e-127	412.0	COG0020@1|root,COG0020@2|Bacteria,2GJCP@201174|Actinobacteria,4DYMM@85010|Pseudonocardiales	201174|Actinobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS1	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.68	ko:K00806,ko:K12503	ko00900,ko01110,map00900,map01110	-	R06447,R08528	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
TLS3_k127_3502874_7	675635.Psed_5921	6.36e-12	66.0	COG1018@1|root,COG1018@2|Bacteria,2HIRR@201174|Actinobacteria,4DYJW@85010|Pseudonocardiales	201174|Actinobacteria	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
TLS3_k127_3502874_4	1120948.KB903244_gene3159	1.972e-54	203.0	COG5207@1|root,COG5207@2|Bacteria,2IKW9@201174|Actinobacteria,4E5J9@85010|Pseudonocardiales	201174|Actinobacteria	O	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
TLS3_k127_3502874_6	1123023.JIAI01000005_gene897	3.57e-12	78.0	COG2388@1|root,COG2388@2|Bacteria,2GQNP@201174|Actinobacteria,4E6IW@85010|Pseudonocardiales	201174|Actinobacteria	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
TLS3_k127_3502874_3	1120948.KB903244_gene3126	4.55e-67	235.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4E1AU@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the thiolase family	fadA3	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
TLS3_k127_3502874_1	405948.SACE_5784	1.527e-176	565.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4E0JB@85010|Pseudonocardiales	201174|Actinobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
TLS3_k127_3502874_2	1120948.KB903229_gene5088	3.629e-108	360.0	COG2207@1|root,COG2207@2|Bacteria,2GITD@201174|Actinobacteria,4E1DB@85010|Pseudonocardiales	201174|Actinobacteria	K	AraC-binding-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
TLS3_k127_3502874_0	1120948.KB903229_gene5087	3.554e-269	832.0	COG0243@1|root,COG0243@2|Bacteria,2GJCK@201174|Actinobacteria,4EED4@85010|Pseudonocardiales	201174|Actinobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
TLS3_k127_3516398_2	1120948.KB903229_gene5262	2.699e-74	265.0	COG2110@1|root,COG2110@2|Bacteria,2IFEC@201174|Actinobacteria,4E3FT@85010|Pseudonocardiales	201174|Actinobacteria	S	Appr-1'-p processing enzyme	lppD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Macro
TLS3_k127_3516398_3	1120948.KB903229_gene5261	3.018e-47	173.0	COG3832@1|root,COG3832@2|Bacteria,2IHY4@201174|Actinobacteria,4E60D@85010|Pseudonocardiales	201174|Actinobacteria	S	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2,SnoaL_2
TLS3_k127_3516398_1	1120948.KB903229_gene5260	3.896e-98	326.0	COG0564@1|root,COG0564@2|Bacteria,2HRKV@201174|Actinobacteria,4EAWH@85010|Pseudonocardiales	201174|Actinobacteria	J	RNA pseudouridylate synthase	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2
TLS3_k127_3516398_0	65497.JODV01000002_gene4447	5.096e-105	350.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4DZYY@85010|Pseudonocardiales	201174|Actinobacteria	HQ	isochorismate	-	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
TLS3_k127_3519002_1	1120948.KB903246_gene3294	3.288e-122	396.0	COG3384@1|root,COG3384@2|Bacteria,2GKTV@201174|Actinobacteria,4DYEZ@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
TLS3_k127_3519002_3	1120948.KB903246_gene3295	1.27e-67	234.0	COG1846@1|root,COG1846@2|Bacteria,2GMV1@201174|Actinobacteria,4E5Q4@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
TLS3_k127_3519002_2	405948.SACE_3984	1.857e-80	285.0	COG2114@1|root,COG2114@2|Bacteria,2I900@201174|Actinobacteria,4E4WE@85010|Pseudonocardiales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1647	Guanylate_cyc
TLS3_k127_3519002_4	405948.SACE_1033	1.851e-41	159.0	COG1826@1|root,COG1826@2|Bacteria,2IR0U@201174|Actinobacteria,4E4Q1@85010|Pseudonocardiales	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	GO:0008150,GO:0040007	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
TLS3_k127_3519002_0	1120948.KB903246_gene3297	1.286e-192	617.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4DZ8E@85010|Pseudonocardiales	201174|Actinobacteria	O	PDZ domain (Also known as DHR or GLGF)	htrA	GO:0000785,GO:0001101,GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005783,GO:0005789,GO:0005829,GO:0005856,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006915,GO:0006950,GO:0006974,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008236,GO:0008630,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009894,GO:0009898,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010467,GO:0010506,GO:0010604,GO:0010638,GO:0010646,GO:0010647,GO:0010648,GO:0010821,GO:0010822,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012501,GO:0012505,GO:0016020,GO:0016021,GO:0016043,GO:0016485,GO:0016540,GO:0016787,GO:0017171,GO:0019222,GO:0019538,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030162,GO:0030163,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031329,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0031984,GO:0032268,GO:0032270,GO:0032526,GO:0032991,GO:0033043,GO:0033554,GO:0033993,GO:0034097,GO:0034599,GO:0034605,GO:0035456,GO:0035458,GO:0035556,GO:0035631,GO:0042175,GO:0042221,GO:0042802,GO:0042981,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043235,GO:0043280,GO:0043281,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044427,GO:0044429,GO:0044432,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045786,GO:0045862,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051082,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051336,GO:0051345,GO:0051604,GO:0051716,GO:0051726,GO:0052547,GO:0052548,GO:0060255,GO:0060548,GO:0065003,GO:0065007,GO:0065009,GO:0070011,GO:0070013,GO:0070206,GO:0070207,GO:0070848,GO:0070887,GO:0071229,GO:0071300,GO:0071310,GO:0071345,GO:0071363,GO:0071396,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0097190,GO:0097193,GO:0097194,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098802,GO:0098827,GO:0140096,GO:1900407,GO:1900408,GO:1901214,GO:1901215,GO:1901564,GO:1901565,GO:1901575,GO:1901700,GO:1901701,GO:1902175,GO:1902176,GO:1902494,GO:1902531,GO:1902532,GO:1902882,GO:1902883,GO:1903146,GO:1903201,GO:1903202,GO:1905286,GO:1905368,GO:1905369,GO:1905370,GO:2000116,GO:2001056,GO:2001233,GO:2001234,GO:2001235,GO:2001236,GO:2001238,GO:2001239,GO:2001241,GO:2001242,GO:2001243,GO:2001267,GO:2001269	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
TLS3_k127_3523765_0	1121272.KB903249_gene1738	0.0	1642.0	COG0110@1|root,COG1020@1|root,COG0110@2|Bacteria,COG1020@2|Bacteria,2I8TI@201174|Actinobacteria,4DBKJ@85008|Micromonosporales	201174|Actinobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Hexapep,Hexapep_2,PP-binding
TLS3_k127_3523765_2	405948.SACE_1993	1.557e-193	614.0	COG3011@1|root,COG3011@2|Bacteria,2GMSU@201174|Actinobacteria,4E82V@85010|Pseudonocardiales	201174|Actinobacteria	S	Lipase maturation factor	LMF	-	-	-	-	-	-	-	-	-	-	-	LMF1
TLS3_k127_3523765_1	1120948.KB903232_gene4685	1.047e-233	735.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4E059@85010|Pseudonocardiales	201174|Actinobacteria	Q	Phytoene dehydrogenase-like oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
TLS3_k127_3530482_5	1120948.KB903248_gene4286	7.986e-56	218.0	COG2227@1|root,COG2227@2|Bacteria,2GMAR@201174|Actinobacteria,4E0YQ@85010|Pseudonocardiales	201174|Actinobacteria	H	Methyltransferase	smtA	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
TLS3_k127_3530482_1	1120948.KB903248_gene4287	1.521e-127	412.0	COG1192@1|root,COG1192@2|Bacteria,2H4UC@201174|Actinobacteria,4DZB6@85010|Pseudonocardiales	201174|Actinobacteria	D	involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
TLS3_k127_3530482_6	1120948.KB903248_gene4288	4.684e-54	195.0	2CGM3@1|root,32S47@2|Bacteria,2GP7H@201174|Actinobacteria,4E632@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3530482_7	1120948.KB903248_gene4289	1.485e-53	191.0	2BAJE@1|root,32405@2|Bacteria,2H8S7@201174|Actinobacteria,4ECUQ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3530482_4	1120948.KB903248_gene4290	1.137e-67	252.0	COG0454@1|root,COG0456@2|Bacteria,2GM3A@201174|Actinobacteria,4E2NA@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
TLS3_k127_3530482_3	1120948.KB903248_gene4291	8.064e-95	319.0	2E8DR@1|root,332S7@2|Bacteria,2GM9C@201174|Actinobacteria,4DZNK@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3153)	lppM	GO:0002682,GO:0002683,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0031347,GO:0031348,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0044464,GO:0045088,GO:0045824,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:0080134	-	-	-	-	-	-	-	-	-	-	DUF3153
TLS3_k127_3530482_0	1120948.KB903248_gene4292	7.467e-165	521.0	COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4DZYK@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
TLS3_k127_3530482_2	1120948.KB903248_gene4293	1.528e-99	333.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4DXA2@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	crtE	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
TLS3_k127_353310_3	1120948.KB903217_gene872	3.447e-63	222.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4EA1T@85010|Pseudonocardiales	201174|Actinobacteria	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R04880,R05233,R05234,R06917,R06927	RC00050,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
TLS3_k127_353310_0	1120948.KB903217_gene874	3.515e-233	726.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria,4E0Y5@85010|Pseudonocardiales	201174|Actinobacteria	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_353310_1	1120948.KB903217_gene877	3.515e-166	532.0	COG2508@1|root,COG2508@2|Bacteria,2GR38@201174|Actinobacteria,4DYEM@85010|Pseudonocardiales	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
TLS3_k127_353310_2	1120948.KB903217_gene878	6.467e-110	389.0	COG0657@1|root,COG0657@2|Bacteria,2GTEV@201174|Actinobacteria,4DZK5@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha beta hydrolase	lipM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
TLS3_k127_353310_4	1120948.KB903217_gene879	1.483e-31	132.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4E0NF@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
TLS3_k127_3536932_2	1120948.KB903229_gene5328	1.756e-48	177.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4DZ2Z@85010|Pseudonocardiales	201174|Actinobacteria	P	Integral membrane protein TerC family	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
TLS3_k127_3536932_3	103733.JNYO01000059_gene8774	6.556e-40	156.0	COG1547@1|root,COG1547@2|Bacteria,2IHUS@201174|Actinobacteria,4E44P@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
TLS3_k127_3536932_1	1120948.KB903229_gene5330	2.488e-77	267.0	COG0693@1|root,COG0693@2|Bacteria,2GMMW@201174|Actinobacteria,4E2WM@85010|Pseudonocardiales	201174|Actinobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
TLS3_k127_3536932_0	1120948.KB903229_gene5331	6.625e-134	434.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4DZ4W@85010|Pseudonocardiales	201174|Actinobacteria	F	3-carboxy-cis,cis-muconate cycloisomerase	pcaB	-	5.5.1.2	ko:K01857	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03307	RC00902	ko00000,ko00001,ko01000	-	-	-	ADSL_C,Lyase_1
TLS3_k127_3545183_7	1120948.KB903217_gene1302	5.953e-36	156.0	2DNQ2@1|root,32YIJ@2|Bacteria,2IPIG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3545183_0	1120948.KB903217_gene1303	2.13e-129	441.0	COG0738@1|root,COG0738@2|Bacteria,2GRCY@201174|Actinobacteria,4E0W7@85010|Pseudonocardiales	201174|Actinobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_3545183_6	1120948.KB903217_gene1306	3.149e-36	145.0	2AYAH@1|root,31QD2@2|Bacteria,2HSG9@201174|Actinobacteria,4EDM9@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2505)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2505
TLS3_k127_3545183_5	1120948.KB903217_gene1304	8.453e-40	148.0	COG1533@1|root,COG1533@2|Bacteria,2GJ2F@201174|Actinobacteria,4DZEQ@85010|Pseudonocardiales	201174|Actinobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3545183_4	35754.JNYJ01000022_gene8106	1.627e-44	168.0	COG1533@1|root,COG1533@2|Bacteria,2GJ2F@201174|Actinobacteria,4DHVB@85008|Micromonosporales	201174|Actinobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3545183_2	477641.MODMU_1175	4.012e-67	241.0	COG1533@1|root,COG1533@2|Bacteria,2GJ2F@201174|Actinobacteria	201174|Actinobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3545183_1	1120948.KB903244_gene3046	2.393e-73	257.0	COG2120@1|root,COG2120@2|Bacteria,2IP0U@201174|Actinobacteria,4ECZA@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TLS3_k127_3545183_8	1120948.KB903244_gene3047	1.482e-18	85.0	COG0438@1|root,COG0438@2|Bacteria,2GIZG@201174|Actinobacteria,4DYB5@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_3547274_2	1027371.GOALK_045_00250	7.781e-89	303.0	COG2324@1|root,COG2324@2|Bacteria,2IIUJ@201174|Actinobacteria,4GC2C@85026|Gordoniaceae	201174|Actinobacteria	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
TLS3_k127_3547274_0	337191.KTR9_4464	1.274e-114	395.0	COG1215@1|root,COG1215@2|Bacteria,2GJZI@201174|Actinobacteria,4GC3W@85026|Gordoniaceae	201174|Actinobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_transf_21,Glycos_transf_2
TLS3_k127_3547274_1	1220583.GOACH_19_00800	9.204e-104	364.0	COG1233@1|root,COG1233@2|Bacteria,2GJAV@201174|Actinobacteria,4GAYT@85026|Gordoniaceae	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	crtI	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
TLS3_k127_3560094_0	1123024.AUII01000011_gene4472	0.0	1267.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4EAJP@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
TLS3_k127_3560094_1	2074.JNYD01000013_gene6841	7.597e-38	144.0	2E7BZ@1|root,331V9@2|Bacteria,2GQHG@201174|Actinobacteria,4E6VF@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of Unknown Function (DUF1540)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
TLS3_k127_3560094_2	2074.JNYD01000013_gene6842	5.886e-13	72.0	2FH3U@1|root,348YH@2|Bacteria,2H80I@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3565153_4	1120948.KB903245_gene3556	8.944e-11	74.0	COG5637@1|root,COG5637@2|Bacteria,2GMK7@201174|Actinobacteria,4DYKA@85010|Pseudonocardiales	201174|Actinobacteria	S	Cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
TLS3_k127_3565153_3	390989.JOEG01000001_gene4959	8.601e-11	69.0	29WE1@1|root,30HZR@2|Bacteria,2HUYC@201174|Actinobacteria,4DGC2@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3565153_5	1206729.BAFZ01000068_gene4183	5.003e-07	58.0	COG1366@1|root,COG1366@2|Bacteria,2HP99@201174|Actinobacteria,4G2HI@85025|Nocardiaceae	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
TLS3_k127_3565153_2	909613.UO65_6460	2.916e-16	85.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	rsbU	GO:0000287,GO:0003674,GO:0003824,GO:0004035,GO:0005488,GO:0005515,GO:0006355,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019219,GO:0019222,GO:0030145,GO:0031323,GO:0031326,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MEDS,PAS_4,STAS,STAS_2,SpoIIE
TLS3_k127_3565153_1	1120948.KB903219_gene747	2.031e-52	197.0	COG2246@1|root,COG2246@2|Bacteria,2IGKV@201174|Actinobacteria,4E4F5@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
TLS3_k127_3565153_0	1120948.KB903219_gene746	1.815e-243	765.0	COG1807@1|root,COG1807@2|Bacteria,2GKH9@201174|Actinobacteria,4DYSK@85010|Pseudonocardiales	201174|Actinobacteria	M	Mycobacterial cell wall arabinan synthesis protein	-	-	-	ko:K11386	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Arabino_trans_C,Arabinose_trans
TLS3_k127_3566352_2	1120948.KB903231_gene4718	2.938e-97	324.0	COG0128@1|root,COG0128@2|Bacteria,2GJKX@201174|Actinobacteria,4DZN4@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
TLS3_k127_3566352_1	1120948.KB903231_gene4719	1.585e-163	534.0	COG1162@1|root,COG1162@2|Bacteria,2GJ37@201174|Actinobacteria,4E0H1@85010|Pseudonocardiales	201174|Actinobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
TLS3_k127_3566352_4	1040989.AWZU01000023_gene4843	4.471e-28	118.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
TLS3_k127_3566352_3	987059.RBXJA2T_12032	3.098e-62	224.0	COG0572@1|root,COG0572@2|Bacteria,1QV2B@1224|Proteobacteria,2VQ8H@28216|Betaproteobacteria,1KKT7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	COG1072 Panthothenate kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,PRK
TLS3_k127_3566352_0	1120948.KB903231_gene4723	3.22e-203	643.0	COG0415@1|root,COG0415@2|Bacteria,2GJPV@201174|Actinobacteria	201174|Actinobacteria	L	FAD binding domain of DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	FAD_binding_7
TLS3_k127_3566352_7	1134445.AJJM01000109_gene3965	6.884e-12	77.0	COG1403@1|root,COG1403@2|Bacteria,2I9UA@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3566352_5	1120950.KB892711_gene2488	2.592e-24	110.0	COG2045@1|root,COG2045@2|Bacteria,2II0K@201174|Actinobacteria,4DQP5@85009|Propionibacteriales	201174|Actinobacteria	H	2-phosphosulpholactate phosphatase	-	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
TLS3_k127_3566446_1	2074.JNYD01000035_gene6699	7.194e-125	411.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria,4DYQ1@85010|Pseudonocardiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
TLS3_k127_3566446_2	2074.JNYD01000035_gene6700	1.31e-99	346.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4DZSI@85010|Pseudonocardiales	201174|Actinobacteria	E	TOBE domain	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
TLS3_k127_3566446_0	1120948.KB903245_gene3458	6.249e-276	864.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4DYMX@85010|Pseudonocardiales	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
TLS3_k127_3567260_1	1120948.KB903245_gene3627	1.822e-107	361.0	COG1196@1|root,COG1196@2|Bacteria,2IIMZ@201174|Actinobacteria,4DYDX@85010|Pseudonocardiales	201174|Actinobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DivIVA
TLS3_k127_3567260_2	1386089.N865_06740	2.118e-20	93.0	2E3EP@1|root,32YDP@2|Bacteria,2GQST@201174|Actinobacteria,4FHYJ@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATP GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3567260_0	1120948.KB903245_gene3636	2.427e-288	891.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4DX5C@85010|Pseudonocardiales	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
TLS3_k127_3572145_3	1352941.M877_18655	3.398e-106	356.0	28HGI@1|root,2Z7SC@2|Bacteria,2GKHQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3572145_1	2074.JNYD01000070_gene6766	2.965e-229	716.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4DZ2J@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
TLS3_k127_3572145_0	1068978.AMETH_4482	1.237e-238	764.0	COG0665@1|root,COG0665@2|Bacteria,2I8QS@201174|Actinobacteria,4E0YA@85010|Pseudonocardiales	201174|Actinobacteria	E	Sarcosine oxidase	soxB	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
TLS3_k127_3572145_4	1068978.AMETH_4483	1.124e-45	166.0	COG4311@1|root,COG4311@2|Bacteria,2IQIZ@201174|Actinobacteria,4E5CD@85010|Pseudonocardiales	201174|Actinobacteria	E	Sarcosine oxidase, delta subunit family	soxD	-	1.5.3.1	ko:K00304	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxD
TLS3_k127_3572145_2	1120948.KB903244_gene2826	6.729e-225	708.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,2GMBK@201174|Actinobacteria,4E081@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the GcvT family	soxA	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2,SoxD
TLS3_k127_3580182_4	1123024.AUII01000001_gene3121	6.82e-56	205.0	COG1414@1|root,COG1414@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
TLS3_k127_3580182_1	263358.VAB18032_17825	1.982e-157	509.0	COG3384@1|root,COG3384@2|Bacteria	2|Bacteria	S	3-carboxyethylcatechol 2,3-dioxygenase activity	hpaD	-	1.13.11.15,1.13.11.74,1.13.11.76	ko:K00455,ko:K15058,ko:K15059	ko00350,ko00627,ko01120,ko01220,map00350,map00627,map01120,map01220	M00533	R03303,R05405	RC00387,RC00643	ko00000,ko00001,ko00002,ko01000	-	-	-	LigB
TLS3_k127_3580182_2	1123024.AUII01000001_gene3118	1.974e-86	314.0	COG3384@1|root,COG3384@2|Bacteria	2|Bacteria	S	3-carboxyethylcatechol 2,3-dioxygenase activity	hpaD	-	1.13.11.15	ko:K00455,ko:K15058	ko00350,ko00627,ko01120,ko01220,map00350,map00627,map01120,map01220	M00533	R03303,R05405	RC00387,RC00643	ko00000,ko00001,ko00002,ko01000	-	-	-	LigB
TLS3_k127_3580182_5	1123024.AUII01000001_gene3117	5.466e-32	126.0	COG4577@1|root,COG4577@2|Bacteria,2H92N@201174|Actinobacteria	201174|Actinobacteria	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
TLS3_k127_3580182_6	263358.VAB18032_17810	5.094e-30	122.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	ccmO	-	-	ko:K04027,ko:K08696,ko:K08700	-	-	-	-	ko00000	-	-	-	BMC
TLS3_k127_3580182_7	1123023.JIAI01000006_gene321	3.797e-17	88.0	294F0@1|root,2ZRUV@2|Bacteria,2HAHB@201174|Actinobacteria	201174|Actinobacteria	S	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
TLS3_k127_3580182_3	1123023.JIAI01000006_gene320	9.457e-78	278.0	COG0574@1|root,COG0574@2|Bacteria,2GMN4@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007,ko:K21787	ko00333,ko00620,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00333,map00620,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00374,M00837,M00838	R00199,R11662,R11673	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
TLS3_k127_3580182_0	1123024.AUII01000001_gene3113	2.549e-167	534.0	COG3848@1|root,COG3848@2|Bacteria,2I3FP@201174|Actinobacteria,4EAD5@85010|Pseudonocardiales	201174|Actinobacteria	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
TLS3_k127_3580983_1	1236902.ANAS01000004_gene3791	6.321e-90	306.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria,4EINR@85012|Streptosporangiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
TLS3_k127_3580983_0	1120948.KB903217_gene1107	7.067e-307	955.0	COG1330@1|root,COG1330@2|Bacteria,2GNVB@201174|Actinobacteria,4E8FA@85010|Pseudonocardiales	201174|Actinobacteria	L	Exodeoxyribonuclease V, gamma subunit	recC	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
TLS3_k127_3584011_7	1120948.KB903245_gene3695	2.568e-37	144.0	2EP16@1|root,33GN1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3584011_6	1120948.KB903245_gene3696	2.991e-45	166.0	2BX7X@1|root,32RMD@2|Bacteria,2IKN7@201174|Actinobacteria,4E4BS@85010|Pseudonocardiales	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3584011_3	1120948.KB903245_gene3698	5.956e-97	323.0	COG2375@1|root,COG2375@2|Bacteria,2GK5X@201174|Actinobacteria,4DZNX@85010|Pseudonocardiales	201174|Actinobacteria	P	Siderophore-interacting protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_9,SIP
TLS3_k127_3584011_5	909613.UO65_5643	1.066e-63	243.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,4E4E5@85010|Pseudonocardiales	201174|Actinobacteria	H	Dihydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
TLS3_k127_3584011_1	1114959.SZMC14600_06887	4.294e-147	478.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4E1ZB@85010|Pseudonocardiales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
TLS3_k127_3584011_2	1120948.KB903229_gene5081	1.957e-132	430.0	COG1948@1|root,COG1948@2|Bacteria,2HAMQ@201174|Actinobacteria,4EAEU@85010|Pseudonocardiales	201174|Actinobacteria	L	ERCC4 domain	-	-	-	-	-	-	-	-	-	-	-	-	ERCC4,Lsr2
TLS3_k127_3584011_4	1120948.KB903245_gene3703	1.001e-73	273.0	COG0572@1|root,COG0572@2|Bacteria,2GMCP@201174|Actinobacteria,4E3NU@85010|Pseudonocardiales	201174|Actinobacteria	F	uridine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3584011_0	1120948.KB903245_gene3704	5.461e-227	709.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4DY6E@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_3584011_8	1120948.KB903245_gene3705	6.665e-37	143.0	COG0515@1|root,COG0515@2|Bacteria	1120948.KB903245_gene3705|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3586670_2	1120948.KB903244_gene2924	4.722e-81	276.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4DXD0@85010|Pseudonocardiales	201174|Actinobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
TLS3_k127_3586670_0	1120948.KB903244_gene2925	5.85e-192	622.0	COG2890@1|root,COG2890@2|Bacteria,2GJPP@201174|Actinobacteria,4DYJU@85010|Pseudonocardiales	201174|Actinobacteria	J	PFAM methyltransferase small	prmC_2	-	-	-	-	-	-	-	-	-	-	-	MTS
TLS3_k127_3586670_1	1120948.KB903244_gene2927	2.084e-83	290.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4DY5T@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigB	GO:0000988,GO:0000990,GO:0001666,GO:0002791,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009410,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS3_k127_3590480_0	1120948.KB903219_gene690	1.294e-141	468.0	COG0754@1|root,COG0754@2|Bacteria,2GMQ5@201174|Actinobacteria,4DXNW@85010|Pseudonocardiales	201174|Actinobacteria	E	Glutathionylspermidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	GSP_synth
TLS3_k127_3590480_5	1120948.KB903219_gene689	1.579e-64	233.0	2CFY3@1|root,34002@2|Bacteria,2IM4B@201174|Actinobacteria,4E4RH@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3590480_3	1120948.KB903219_gene688	6.071e-125	414.0	2BXNT@1|root,30VN0@2|Bacteria,2H72W@201174|Actinobacteria,4DXNH@85010|Pseudonocardiales	201174|Actinobacteria	S	Septum formation	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Septum_form
TLS3_k127_3590480_7	1120948.KB903219_gene687	2.523e-49	181.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4E4P1@85010|Pseudonocardiales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
TLS3_k127_3590480_6	1120948.KB903219_gene685	2.583e-63	225.0	COG0406@1|root,COG0406@2|Bacteria,2GP71@201174|Actinobacteria,4E3GB@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the phosphoglycerate mutase family	pgmB	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
TLS3_k127_3590480_2	1120948.KB903219_gene684	2.072e-125	419.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4DZ1V@85010|Pseudonocardiales	201174|Actinobacteria	E	Prephenate dehydratase	pheA	GO:0003674,GO:0003824,GO:0004664,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016597,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0031406,GO:0033585,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046983,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
TLS3_k127_3590480_1	1120948.KB903219_gene683	6.348e-130	422.0	COG0124@1|root,COG0124@2|Bacteria,2GJXW@201174|Actinobacteria,4DZIE@85010|Pseudonocardiales	201174|Actinobacteria	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3590480_4	1120948.KB903219_gene682	1.308e-84	288.0	2E6J0@1|root,33163@2|Bacteria,2HEIF@201174|Actinobacteria,4E0R2@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2470)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2470
TLS3_k127_3590480_9	1120948.KB903219_gene681	2.766e-38	153.0	COG0477@1|root,COG2814@2|Bacteria,2I5V4@201174|Actinobacteria,4EE6C@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Domain of unknown function (DUF3817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3817
TLS3_k127_3590480_8	1120948.KB903219_gene680	1.964e-39	152.0	COG1566@1|root,COG1566@2|Bacteria,2ISAW@201174|Actinobacteria,4E5VY@85010|Pseudonocardiales	201174|Actinobacteria	V	Glucitol operon activator	lprD	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3590480_11	1198452.Jab_1c16620	2.824e-05	51.0	COG0654@1|root,COG0654@2|Bacteria,1R7KI@1224|Proteobacteria,2VXH3@28216|Betaproteobacteria,47554@75682|Oxalobacteraceae	28216|Betaproteobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
TLS3_k127_3590480_10	1120948.KB903220_gene34	1.931e-09	60.0	COG0654@1|root,COG0654@2|Bacteria,2GJ9V@201174|Actinobacteria,4DYZR@85010|Pseudonocardiales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
TLS3_k127_3607364_2	1445613.JALM01000017_gene5930	3.007e-32	126.0	COG0698@1|root,COG0698@2|Bacteria,2GKJG@201174|Actinobacteria,4E2S1@85010|Pseudonocardiales	201174|Actinobacteria	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
TLS3_k127_3607364_0	1120948.KB903247_gene4427	0.0	1272.0	COG2170@1|root,COG2308@1|root,COG2170@2|Bacteria,COG2308@2|Bacteria,2GN0J@201174|Actinobacteria,4E0HH@85010|Pseudonocardiales	201174|Actinobacteria	S	Circularly permuted ATP-grasp type 2	gcs2	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	Alpha-E,CP_ATPgrasp_1,CP_ATPgrasp_2,GCS2
TLS3_k127_3607364_1	1120948.KB903247_gene4426	1.754e-101	332.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4E24C@85010|Pseudonocardiales	201174|Actinobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
TLS3_k127_3611042_0	1120948.KB903218_gene2098	1.013e-201	632.0	COG2072@1|root,COG2072@2|Bacteria,2H38Q@201174|Actinobacteria,4EA65@85010|Pseudonocardiales	201174|Actinobacteria	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,NAD_binding_8,Pyr_redox_2
TLS3_k127_3611042_1	675635.Psed_0542	1.265e-156	509.0	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria,4E1ZU@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	6.2.1.7	ko:K15868	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_3611042_2	1120948.KB903218_gene1921	1.34e-13	72.0	COG1595@1|root,COG1595@2|Bacteria,2GM8T@201174|Actinobacteria,4DY2F@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigD	GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS3_k127_3626698_5	1120948.KB903229_gene5283	1.069e-83	284.0	COG1802@1|root,COG1802@2|Bacteria,2GMI2@201174|Actinobacteria,4E2SR@85010|Pseudonocardiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
TLS3_k127_3626698_8	2074.JNYD01000040_gene2979	7.177e-52	188.0	COG3193@1|root,COG3193@2|Bacteria,2IHWI@201174|Actinobacteria,4E4TU@85010|Pseudonocardiales	201174|Actinobacteria	S	protein, possibly involved in utilization of glycolate and propanediol	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
TLS3_k127_3626698_9	1445613.JALM01000081_gene939	1.225e-48	178.0	COG4910@1|root,COG4910@2|Bacteria,2IN09@201174|Actinobacteria,4E57F@85010|Pseudonocardiales	201174|Actinobacteria	Q	Dehydratase small subunit	pduE	-	4.2.1.28	ko:K13920	ko00640,map00640	-	R02376	RC00707	ko00000,ko00001,ko01000	-	-	-	Dehydratase_SU
TLS3_k127_3626698_0	2074.JNYD01000008_gene1044	7.323e-292	905.0	COG4909@1|root,COG4909@2|Bacteria,2GP0B@201174|Actinobacteria,4E0SJ@85010|Pseudonocardiales	201174|Actinobacteria	Q	Dehydratase large subunit	pduC	-	4.2.1.28	ko:K01699	ko00640,map00640	-	R02376	RC00707	ko00000,ko00001,ko01000	-	-	-	Dehydratase_LU
TLS3_k127_3626698_6	43354.JOIJ01000001_gene86	5.154e-77	263.0	COG4909@1|root,COG4909@2|Bacteria,2HPSF@201174|Actinobacteria,4DZAW@85010|Pseudonocardiales	201174|Actinobacteria	Q	Dehydratase medium subunit	-	-	4.2.1.28	ko:K13919	ko00640,map00640	-	R02376	RC00707	ko00000,ko00001,ko01000	-	-	-	Dehydratase_MU
TLS3_k127_3626698_1	1068978.AMETH_5914	3.624e-241	768.0	COG0849@1|root,COG0849@2|Bacteria,2GNUI@201174|Actinobacteria,4E1CU@85010|Pseudonocardiales	201174|Actinobacteria	D	Diol dehydratase reactivase ATPase-like domain	dhaF	-	-	-	-	-	-	-	-	-	-	-	DDR
TLS3_k127_3626698_10	1306174.JODP01000005_gene1732	3.783e-18	100.0	2EB43@1|root,3354T@2|Bacteria,2GYDA@201174|Actinobacteria	201174|Actinobacteria	S	Dehydratase medium subunit	-	-	-	-	-	-	-	-	-	-	-	-	Dehydratase_MU
TLS3_k127_3626698_3	1120948.KB903229_gene5284	1.23e-142	469.0	COG4667@1|root,COG4667@2|Bacteria,2I8R7@201174|Actinobacteria,4DZKI@85010|Pseudonocardiales	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
TLS3_k127_3626698_2	1120948.KB903229_gene5286	5.454e-229	729.0	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria,4DXQI@85010|Pseudonocardiales	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
TLS3_k127_3626698_4	1120948.KB903229_gene5287	5.945e-117	381.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4DYMB@85010|Pseudonocardiales	201174|Actinobacteria	K	RNA polymerase sigma factor, sigma-70 family	sigF	GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS3_k127_3626698_7	1120948.KB903217_gene1147	6.085e-67	234.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,2GJB4@201174|Actinobacteria,4E215@85010|Pseudonocardiales	201174|Actinobacteria	CE	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
TLS3_k127_3636003_0	1120948.KB903218_gene2040	4.28e-216	681.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria,4DXGN@85010|Pseudonocardiales	201174|Actinobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	kasA	GO:0001666,GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009628,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019367,GO:0019752,GO:0030312,GO:0030497,GO:0032787,GO:0034645,GO:0036293,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0070482,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576	2.3.1.179	ko:K09458,ko:K11609	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
TLS3_k127_3636003_4	1120948.KB903218_gene2041	8.46e-32	140.0	COG0236@1|root,COG0236@2|Bacteria,2IQ43@201174|Actinobacteria,4E5I2@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
TLS3_k127_3636003_1	1120948.KB903218_gene2042	4.206e-150	496.0	COG0332@1|root,COG0332@2|Bacteria,2GJP8@201174|Actinobacteria,4DXQM@85010|Pseudonocardiales	201174|Actinobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
TLS3_k127_3636003_2	1120948.KB903218_gene2043	8.541e-132	427.0	COG0331@1|root,COG0331@2|Bacteria,2GME0@201174|Actinobacteria,4DXFJ@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Acyl transferase	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
TLS3_k127_3636003_3	1120948.KB903218_gene2044	5.691e-96	320.0	COG2508@1|root,COG2508@2|Bacteria,2GN0S@201174|Actinobacteria,4DZ0N@85010|Pseudonocardiales	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
TLS3_k127_3637490_4	1120948.KB903246_gene3365	9.815e-89	306.0	2F0WB@1|root,33TXY@2|Bacteria,2ID9H@201174|Actinobacteria,4E6TP@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3637490_2	909613.UO65_5163	2.585e-171	560.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4DYE8@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
TLS3_k127_3637490_5	405948.SACE_4786	1.141e-37	150.0	COG1376@1|root,COG1376@2|Bacteria,2IQZG@201174|Actinobacteria,4EF0S@85010|Pseudonocardiales	201174|Actinobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
TLS3_k127_3637490_0	1120948.KB903246_gene3368	5.121e-264	817.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4DZFS@85010|Pseudonocardiales	201174|Actinobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
TLS3_k127_3637490_1	1120948.KB903246_gene3369	3.979e-235	737.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria,4DXPV@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
TLS3_k127_3637490_6	1120948.KB903225_gene5562	4.645e-31	139.0	2DNZR@1|root,32ZYK@2|Bacteria,2GQYS@201174|Actinobacteria,4E6YA@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF3817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3817
TLS3_k127_3637490_3	2074.JNYD01000026_gene692	2.465e-161	517.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4E07V@85010|Pseudonocardiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
TLS3_k127_3637490_7	1268303.RHODMAR_3014	4.698e-13	68.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GNDC@201174|Actinobacteria,4FWHR@85025|Nocardiaceae	201174|Actinobacteria	F	IMP dehydrogenase / GMP reductase domain	guaB1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
TLS3_k127_3648052_7	35754.JNYJ01000067_gene4114	2.856e-25	105.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4DCZE@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_3648052_4	35754.JNYJ01000067_gene4114	1.042e-68	246.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4DCZE@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_3648052_3	35754.JNYJ01000067_gene4113	2.648e-115	388.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria,4DDFF@85008|Micromonosporales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TLS3_k127_3648052_0	1123024.AUII01000015_gene3750	1.646e-154	511.0	COG0654@1|root,COG0654@2|Bacteria,2GK7I@201174|Actinobacteria,4DXC9@85010|Pseudonocardiales	201174|Actinobacteria	CH	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored
TLS3_k127_3648052_2	675635.Psed_6299	7.8e-117	413.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4E1HN@85010|Pseudonocardiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_3648052_5	35754.JNYJ01000067_gene4112	8.321e-68	238.0	2C3NF@1|root,30ZWG@2|Bacteria,2IFY6@201174|Actinobacteria,4DCQJ@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1772
TLS3_k127_3648052_8	644283.Micau_1082	1.23e-16	91.0	2BVH7@1|root,32QVU@2|Bacteria,2IN4G@201174|Actinobacteria,4DFU6@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3648052_1	1120948.KB903240_gene3869	5.601e-145	466.0	COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria,4DYPU@85010|Pseudonocardiales	201174|Actinobacteria	S	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine	egtD	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
TLS3_k127_3648052_6	1120948.KB903240_gene3870	5.819e-56	203.0	COG0121@1|root,COG0121@2|Bacteria,2GXCD@201174|Actinobacteria,4DZMF@85010|Pseudonocardiales	201174|Actinobacteria	S	Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	egtC	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006518,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006749,GO:0006751,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0019439,GO:0019752,GO:0032991,GO:0034641,GO:0042219,GO:0042398,GO:0043171,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0051186,GO:0051187,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0061672,GO:0071704,GO:0071944,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1905368	3.5.1.118	ko:K07008	ko00340,map00340	-	R11021	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	GATase_6
TLS3_k127_3649890_0	1120948.KB903240_gene3893	0.0	1012.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4DZ5Q@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
TLS3_k127_3649890_3	1120948.KB903240_gene3892	1.194e-161	524.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,4DXM2@85010|Pseudonocardiales	201174|Actinobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
TLS3_k127_3649890_9	1123023.JIAI01000003_gene2949	7.533e-50	188.0	COG2852@1|root,COG2852@2|Bacteria,2GN40@201174|Actinobacteria,4E7WA@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
TLS3_k127_3649890_5	1120948.KB903240_gene3891	2.082e-126	413.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria,4E09P@85010|Pseudonocardiales	201174|Actinobacteria	C	NADPH quinone reductase	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_3649890_6	1120948.KB903240_gene3890	2.183e-119	392.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4DYYZ@85010|Pseudonocardiales	201174|Actinobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
TLS3_k127_3649890_7	1120948.KB903240_gene3889	2.522e-97	336.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,4DXEN@85010|Pseudonocardiales	201174|Actinobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
TLS3_k127_3649890_4	675635.Psed_3401	1.668e-144	463.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4DXI2@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	drrA_2	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_3649890_1	1120948.KB903240_gene3887	1.072e-243	762.0	2DBIT@1|root,2Z9GU@2|Bacteria,2GN03@201174|Actinobacteria,4DZ2H@85010|Pseudonocardiales	201174|Actinobacteria	S	Carotene biosynthesis associated membrane protein	mptB	-	-	ko:K14337,ko:K14339	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	GT87
TLS3_k127_3649890_8	1120948.KB903240_gene3886	1.638e-76	265.0	COG2345@1|root,COG2345@2|Bacteria,2GN8W@201174|Actinobacteria,4DY18@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	sufR	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
TLS3_k127_3649890_2	1120948.KB903240_gene3885	3.417e-178	568.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4DXK0@85010|Pseudonocardiales	201174|Actinobacteria	O	assembly protein sufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
TLS3_k127_3649991_4	1206737.BAGF01000070_gene4370	6.884e-06	49.0	2EKIG@1|root,33E8D@2|Bacteria,2INGR@201174|Actinobacteria,4G1ZI@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3649991_2	675635.Psed_1727	9.736e-57	209.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria,4E4DR@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS3_k127_3649991_0	1123320.KB889682_gene2166	1.588e-121	410.0	COG0583@1|root,COG0583@2|Bacteria,2GJ4Z@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS3_k127_3649991_1	1089544.KB912942_gene993	1.167e-91	306.0	2CPHS@1|root,32SJ6@2|Bacteria,2IAWF@201174|Actinobacteria,4EC1V@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3649991_3	101510.RHA1_ro03814	1.377e-16	91.0	COG1028@1|root,COG1028@2|Bacteria,2GJ9X@201174|Actinobacteria,4FVDT@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
TLS3_k127_365162_2	345341.KUTG_02775	1.841e-13	72.0	COG2306@1|root,COG2306@2|Bacteria,2IFT9@201174|Actinobacteria,4E2WD@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF402)	-	-	-	ko:K09146	-	-	-	-	ko00000	-	-	-	-
TLS3_k127_365162_1	1120948.KB903240_gene4057	5.566e-98	331.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4DYSR@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
TLS3_k127_365162_0	1120948.KB903240_gene4059	1.783e-104	341.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4DYWG@85010|Pseudonocardiales	201174|Actinobacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
TLS3_k127_3661374_4	1120948.KB903240_gene3824	9.976e-153	492.0	COG2271@1|root,COG2271@2|Bacteria,2H9HJ@201174|Actinobacteria,4E2C3@85010|Pseudonocardiales	201174|Actinobacteria	G	Major Facilitator Superfamily	-	GO:0005575,GO:0005576	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
TLS3_k127_3661374_11	1449976.KALB_6757	3.88e-34	141.0	COG0454@1|root,COG0456@2|Bacteria,2I2E3@201174|Actinobacteria,4EDPG@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_3661374_2	1120948.KB903240_gene3821	6.435e-235	732.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DZ7U@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0016020,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1559	PALP,Thr_dehydrat_C
TLS3_k127_3661374_9	1068980.ARVW01000001_gene3067	2.669e-63	232.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria,4E41G@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_3
TLS3_k127_3661374_8	1068978.AMETH_0125	8.33e-83	297.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4E2DS@85010|Pseudonocardiales	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_3661374_5	1120950.KB892796_gene2244	1.137e-147	483.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4DPG2@85009|Propionibacteriales	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	ko:K04753	-	-	-	-	ko00000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
TLS3_k127_3661374_13	1120950.KB892760_gene5753	2.896e-08	62.0	2EE2V@1|root,337XG@2|Bacteria,2GTDI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3661374_0	287986.DV20_09855	3.49e-281	876.0	COG0326@1|root,COG0326@2|Bacteria,2GNPQ@201174|Actinobacteria,4DZ66@85010|Pseudonocardiales	201174|Actinobacteria	O	Molecular chaperone. Has ATPase activity	htpG	GO:0000302,GO:0000303,GO:0000305,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0010035,GO:0016020,GO:0030312,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071450,GO:0071451,GO:0071944,GO:1901700,GO:1901701	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
TLS3_k127_3661374_3	1120948.KB903240_gene3819	7.182e-178	569.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,4DXNA@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_3661374_10	767029.HMPREF9154_3146	7.702e-61	216.0	COG1848@1|root,COG1848@2|Bacteria,2GPX7@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
TLS3_k127_3661374_12	1298864.AUEQ01000009_gene2690	1.07e-14	86.0	COG3905@1|root,COG3905@2|Bacteria,2GWKG@201174|Actinobacteria,23BZP@1762|Mycobacteriaceae	201174|Actinobacteria	K	Ribbon-helix-helix protein, copG family	vapB43	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944	-	-	-	-	-	-	-	-	-	-	RHH_1
TLS3_k127_3661374_6	66373.JOFQ01000001_gene1591	1.456e-131	440.0	COG2175@1|root,COG2175@2|Bacteria,2HE90@201174|Actinobacteria	201174|Actinobacteria	Q	taurine catabolism dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	TauD
TLS3_k127_3661374_7	1449976.KALB_6150	1.943e-105	353.0	COG1020@1|root,COG3208@1|root,COG1020@2|Bacteria,COG3208@2|Bacteria,2GISR@201174|Actinobacteria,4DY6C@85010|Pseudonocardiales	201174|Actinobacteria	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
TLS3_k127_3661374_1	1120948.KB903222_gene582	3.124e-279	877.0	COG0110@1|root,COG1020@1|root,COG0110@2|Bacteria,COG1020@2|Bacteria,2I8TI@201174|Actinobacteria,4E1Y1@85010|Pseudonocardiales	201174|Actinobacteria	Q	Phosphopantetheine attachment site	nrps4	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Hexapep,Hexapep_2,PP-binding
TLS3_k127_3665697_7	1120948.KB903229_gene5383	2.254e-34	134.0	COG1335@1|root,COG1335@2|Bacteria,2GPE0@201174|Actinobacteria,4E5AM@85010|Pseudonocardiales	201174|Actinobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
TLS3_k127_3665697_6	1120948.KB903229_gene5382	2.71e-38	156.0	COG3564@1|root,COG3564@2|Bacteria,2IKTA@201174|Actinobacteria,4E4AR@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF779)	-	-	-	ko:K09959	-	-	-	-	ko00000	-	-	-	DUF779
TLS3_k127_3665697_5	1232429.CBLL010000111_gene2416	8.932e-42	166.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,1W7PU@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	aldA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136	-	ko:K00138,ko:K18370	ko00010,ko00620,ko00640,ko01100,ko01110,ko01120,map00010,map00620,map00640,map01100,map01110,map01120	-	R00711,R10703	RC00047,RC00545	ko00000,ko00001,ko01000	-	-	-	Aldedh
TLS3_k127_3665697_8	1120948.KB903229_gene5380	1.135e-06	61.0	COG3284@1|root,COG3284@2|Bacteria,2GJV4@201174|Actinobacteria,4DY1W@85010|Pseudonocardiales	201174|Actinobacteria	KQ	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF
TLS3_k127_3665697_3	1120948.KB903229_gene5377	4.589e-114	374.0	COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria,4DXV1@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
TLS3_k127_3665697_4	1120948.KB903229_gene5376	1.664e-63	223.0	COG0853@1|root,COG0853@2|Bacteria,2IHTC@201174|Actinobacteria,4E2JG@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	GO:0003674,GO:0003824,GO:0004068,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006523,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
TLS3_k127_3665697_0	1120948.KB903229_gene5375	3.778e-145	482.0	COG0414@1|root,COG0414@2|Bacteria,2GJEQ@201174|Actinobacteria,4DYWS@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
TLS3_k127_3665697_1	1120948.KB903229_gene5374	5.42e-134	436.0	COG5495@1|root,COG5495@2|Bacteria,2I2F6@201174|Actinobacteria,4DZM6@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
TLS3_k127_3665697_2	1120948.KB903229_gene5373	1.28e-128	416.0	COG2339@1|root,COG2339@2|Bacteria,2GKR5@201174|Actinobacteria,4DZMH@85010|Pseudonocardiales	201174|Actinobacteria	NU	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
TLS3_k127_3668635_1	1120948.KB903245_gene3581	2.814e-142	456.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4E0JQ@85010|Pseudonocardiales	201174|Actinobacteria	C	Electron transfer flavoprotein	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
TLS3_k127_3668635_4	1120948.KB903245_gene3582	8.412e-16	79.0	29U2Z@1|root,30FCA@2|Bacteria,2HP7I@201174|Actinobacteria,4E7TR@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3668635_2	656024.FsymDg_0034	1.344e-109	362.0	COG0223@1|root,COG0223@2|Bacteria,2GN1Z@201174|Actinobacteria,4EU60@85013|Frankiales	201174|Actinobacteria	J	PFAM Formyl transferase	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
TLS3_k127_3668635_3	33876.JNXY01000004_gene1540	1.257e-26	125.0	COG0614@1|root,COG0614@2|Bacteria,2HU5V@201174|Actinobacteria,4DFIF@85008|Micromonosporales	201174|Actinobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
TLS3_k127_3668635_0	994479.GL877878_gene2919	4.895e-179	598.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4DXHP@85010|Pseudonocardiales	201174|Actinobacteria	Q	non-ribosomal peptide synthetase	-	-	-	ko:K04780	ko01053,map01053	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
TLS3_k127_3672016_1	103733.JNYO01000004_gene8010	1.529e-10	74.0	COG0443@1|root,COG0443@2|Bacteria,2GMNN@201174|Actinobacteria,4DZJ1@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the heat shock protein 70 family	hscA	-	-	-	-	-	-	-	-	-	-	-	HSP70,PQQ_2,WD40
TLS3_k127_3672016_0	1120948.KB903217_gene1584	5.508e-168	538.0	COG1674@1|root,COG1674@2|Bacteria,2GJBR@201174|Actinobacteria,4DZA2@85010|Pseudonocardiales	201174|Actinobacteria	D	PFAM FtsK SpoIIIE family	eccCa	GO:0002790,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0020012,GO:0030312,GO:0030682,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0040007,GO:0042783,GO:0042886,GO:0043207,GO:0044110,GO:0044116,GO:0044117,GO:0044315,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0075136	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE
TLS3_k127_3686068_0	1120948.KB903240_gene3956	4.259e-192	609.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4DXVE@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
TLS3_k127_3686068_1	1123024.AUII01000027_gene2662	1.214e-49	192.0	COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,4E3CY@85010|Pseudonocardiales	201174|Actinobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
TLS3_k127_3687408_3	2074.JNYD01000003_gene3961	3.145e-85	290.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4E8GY@85010|Pseudonocardiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_3687408_5	570268.ANBB01000038_gene3365	3.108e-52	190.0	COG5516@1|root,COG5516@2|Bacteria,2GNZF@201174|Actinobacteria,4EKPU@85012|Streptosporangiales	201174|Actinobacteria	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
TLS3_k127_3687408_6	1449068.JMLQ01000001_gene763	4.13e-35	139.0	COG0640@1|root,COG0640@2|Bacteria,2IHVU@201174|Actinobacteria,4G1PI@85025|Nocardiaceae	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
TLS3_k127_3687408_7	1220583.GOACH_01_00770	5.573e-13	74.0	COG2367@1|root,COG2367@2|Bacteria,2IISY@201174|Actinobacteria,4GFZ3@85026|Gordoniaceae	201174|Actinobacteria	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
TLS3_k127_3687408_1	1120948.KB903229_gene5027	1.2e-172	560.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4DYB0@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase III, delta	holB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
TLS3_k127_3687408_0	1123024.AUII01000014_gene4312	1.216e-219	701.0	COG0125@1|root,COG0477@1|root,COG0125@2|Bacteria,COG0477@2|Bacteria,2GNTI@201174|Actinobacteria,4DYRV@85010|Pseudonocardiales	201174|Actinobacteria	EFGP	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_3,Thymidylate_kin
TLS3_k127_3687408_4	2074.JNYD01000026_gene628	2.857e-68	235.0	COG1846@1|root,COG1846@2|Bacteria,2IQFP@201174|Actinobacteria,4E4X9@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
TLS3_k127_3687408_2	2074.JNYD01000026_gene629	5.564e-109	356.0	COG1182@1|root,COG1182@2|Bacteria,2GJEE@201174|Actinobacteria,4E31A@85010|Pseudonocardiales	201174|Actinobacteria	I	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity	azoR	-	-	ko:K01118	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_2
TLS3_k127_3688660_0	28042.GU90_18370	4.511e-122	393.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria,4DYQB@85010|Pseudonocardiales	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
TLS3_k127_3688660_2	1120948.KB903245_gene3638	6.065e-41	166.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4E5X4@85010|Pseudonocardiales	201174|Actinobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
TLS3_k127_3688660_1	1120948.KB903245_gene3637	1.557e-71	245.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,4DXSX@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
TLS3_k127_3691940_2	1429046.RR21198_5873	2.716e-49	181.0	COG3185@1|root,COG3185@2|Bacteria,2GJNC@201174|Actinobacteria,4FVPF@85025|Nocardiaceae	201174|Actinobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
TLS3_k127_3691940_0	1123023.JIAI01000021_gene2389	1.13e-119	399.0	COG2141@1|root,COG2141@2|Bacteria,2GNE9@201174|Actinobacteria,4DZRQ@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_3691940_1	749927.AMED_5310	1.794e-65	226.0	COG1960@1|root,COG1960@2|Bacteria,2GVSU@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	ko:K11731	ko00281,map00281	-	R08089	RC01893	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_3696472_4	1035308.AQYY01000001_gene2041	1.184e-07	64.0	COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,24BJV@186801|Clostridia,2676T@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS3_k127_3696472_0	1120948.KB903246_gene3421	4.324e-203	640.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,4DXVJ@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
TLS3_k127_3696472_2	1120948.KB903246_gene3422	6.858e-20	104.0	COG1977@1|root,COG1977@2|Bacteria,2IQIT@201174|Actinobacteria,4E6FW@85010|Pseudonocardiales	201174|Actinobacteria	H	Molybdopterin converting factor, small subunit	moaD2	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
TLS3_k127_3696472_1	1120948.KB903246_gene3423	1.528e-53	199.0	COG0350@1|root,COG0350@2|Bacteria,2IGZ1@201174|Actinobacteria,4E6E1@85010|Pseudonocardiales	201174|Actinobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
TLS3_k127_3696472_3	675635.Psed_4298	6.263e-19	89.0	COG1877@1|root,COG1877@2|Bacteria,2H9EY@201174|Actinobacteria,4ECE1@85010|Pseudonocardiales	201174|Actinobacteria	G	trehalose-phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3697477_6	1385519.N801_11775	3.294e-86	296.0	COG4325@1|root,COG4325@2|Bacteria,2GWFP@201174|Actinobacteria,4FGEH@85021|Intrasporangiaceae	201174|Actinobacteria	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
TLS3_k127_3697477_5	1123024.AUII01000044_gene611	1.051e-100	339.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4E8BC@85010|Pseudonocardiales	201174|Actinobacteria	O	C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
TLS3_k127_3697477_14	1120948.KB903227_gene4852	3.949e-41	157.0	COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria,4E5G5@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
TLS3_k127_3697477_3	485913.Krac_5329	5.915e-125	417.0	COG2124@1|root,COG2124@2|Bacteria,2G5KX@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
TLS3_k127_3697477_1	35754.JNYJ01000023_gene8258	1.214e-170	557.0	COG0477@1|root,COG2814@2|Bacteria,2H32P@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_3697477_16	448385.sce8247	1.699e-22	105.0	COG1309@1|root,COG1309@2|Bacteria,1N45Z@1224|Proteobacteria,432D4@68525|delta/epsilon subdivisions,2WYS6@28221|Deltaproteobacteria,2Z0GQ@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
TLS3_k127_3697477_9	2074.JNYD01000004_gene4974	2.46e-65	226.0	COG1846@1|root,COG1846@2|Bacteria,2IHTR@201174|Actinobacteria,4E406@85010|Pseudonocardiales	201174|Actinobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
TLS3_k127_3697477_7	1048339.KB913029_gene3441	5.154e-77	263.0	2AEJC@1|root,314EV@2|Bacteria,2GMTI@201174|Actinobacteria,4ET1I@85013|Frankiales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
TLS3_k127_3697477_8	1463825.JNXC01000001_gene5675	1.972e-67	244.0	COG0454@1|root,COG0456@2|Bacteria,2I2E3@201174|Actinobacteria,4E5CK@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_3697477_17	1123258.AQXZ01000011_gene1557	2.314e-19	100.0	COG2867@1|root,COG2867@2|Bacteria,2IIFW@201174|Actinobacteria,4G1PE@85025|Nocardiaceae	201174|Actinobacteria	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_3697477_4	1001240.GY21_02840	4.191e-115	396.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4FRQ7@85023|Microbacteriaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_3697477_11	1054860.KB913030_gene6134	1.002e-53	201.0	2A1WW@1|root,30Q6B@2|Bacteria,2HGNT@201174|Actinobacteria	201174|Actinobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
TLS3_k127_3697477_19	211114.JOEF01000024_gene37	9.58e-08	58.0	2B53E@1|root,31XWX@2|Bacteria,2GZUC@201174|Actinobacteria,4E7N6@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3697477_2	882083.SacmaDRAFT_5078	4.228e-152	505.0	COG0025@1|root,COG0025@2|Bacteria,2I37Q@201174|Actinobacteria,4DYM3@85010|Pseudonocardiales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
TLS3_k127_3697477_12	105425.BBPL01000059_gene5056	6.41e-49	179.0	COG3118@1|root,COG3118@2|Bacteria,2IHQV@201174|Actinobacteria,2NISF@228398|Streptacidiphilus	201174|Actinobacteria	O	Thioredoxin-like domain	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
TLS3_k127_3697477_10	1089546.AQUI01000002_gene3134	7.153e-62	220.0	COG0607@1|root,COG0607@2|Bacteria,2IB6H@201174|Actinobacteria,4097J@622450|Actinopolysporales	201174|Actinobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Rhodanese
TLS3_k127_3697477_15	675635.Psed_6856	3.927e-24	108.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS3_k127_3697477_13	2074.JNYD01000002_gene5575	2.397e-48	190.0	COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,4E49P@85010|Pseudonocardiales	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_3697477_0	1268303.RHODMAR_0922	2.935e-179	572.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria,4FXJT@85025|Nocardiaceae	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
TLS3_k127_3697477_18	1123024.AUII01000032_gene3779	4.585e-13	70.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,4DY89@85010|Pseudonocardiales	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
TLS3_k127_3697642_1	526225.Gobs_0485	1.153e-41	157.0	COG2146@1|root,COG2146@2|Bacteria,2GVQV@201174|Actinobacteria,4EWIY@85013|Frankiales	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
TLS3_k127_3697642_2	2074.JNYD01000027_gene7360	1.25e-32	130.0	2E1PZ@1|root,32WD8@2|Bacteria,2ISES@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3697642_0	2074.JNYD01000026_gene695	1.353e-95	319.0	COG2755@1|root,COG2755@2|Bacteria,2GNBP@201174|Actinobacteria,4E1VK@85010|Pseudonocardiales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS3_k127_3710403_10	1120948.KB903247_gene4513	9.159e-111	364.0	COG1024@1|root,COG1024@2|Bacteria,2GJ0N@201174|Actinobacteria,4DZN3@85010|Pseudonocardiales	201174|Actinobacteria	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
TLS3_k127_3710403_11	1120948.KB903224_gene358	3.769e-76	264.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_3710403_5	1120948.KB903247_gene4510	3.088e-189	593.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4DZ6G@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Alcohol dehydrogenase	yogA	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_3710403_7	1120948.KB903247_gene4596	3.324e-125	410.0	COG0596@1|root,COG0596@2|Bacteria,2GMMB@201174|Actinobacteria,4DZBE@85010|Pseudonocardiales	201174|Actinobacteria	S	hydrolase or acyltransferase of alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_3710403_2	1120948.KB903247_gene4508	7.264e-243	768.0	COG4529@1|root,COG4529@2|Bacteria,2GMVT@201174|Actinobacteria,4DX6W@85010|Pseudonocardiales	201174|Actinobacteria	S	FAD-NAD(P)-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_9
TLS3_k127_3710403_1	1120948.KB903247_gene4507	1.004e-272	852.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4DZA4@85010|Pseudonocardiales	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	deaD	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K05592,ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
TLS3_k127_3710403_6	1123024.AUII01000004_gene1720	5.315e-147	477.0	COG4106@1|root,COG4106@2|Bacteria,2I3QF@201174|Actinobacteria,4E20K@85010|Pseudonocardiales	201174|Actinobacteria	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
TLS3_k127_3710403_14	1267534.KB906754_gene3349	6.842e-19	101.0	COG2329@1|root,COG5485@1|root,COG2329@2|Bacteria,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
TLS3_k127_3710403_9	479431.Namu_2609	4.448e-112	382.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria,4EUC0@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
TLS3_k127_3710403_0	1120948.KB903247_gene4506	0.0	1184.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4DX6U@85010|Pseudonocardiales	201174|Actinobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
TLS3_k127_3710403_12	1120948.KB903247_gene4505	2.31e-35	136.0	COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,4E5HA@85010|Pseudonocardiales	201174|Actinobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
TLS3_k127_3710403_8	1120948.KB903247_gene4504	2.262e-124	407.0	COG1466@1|root,COG1466@2|Bacteria,2GNMZ@201174|Actinobacteria,4DZCD@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
TLS3_k127_3710403_17	1123024.AUII01000008_gene1834	4.089e-05	48.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4DXGV@85010|Pseudonocardiales	201174|Actinobacteria	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
TLS3_k127_3710403_4	1120948.KB903247_gene4503	1.057e-239	746.0	COG0498@1|root,COG0498@2|Bacteria,2GNM0@201174|Actinobacteria,4DYA8@85010|Pseudonocardiales	201174|Actinobacteria	E	Threonine synthase	thrC3	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_3710403_15	1078020.KEK_01900	1.466e-17	88.0	29DTG@1|root,300RC@2|Bacteria,2HCYB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3710403_3	1120948.KB903247_gene4502	1.198e-242	760.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4DXGV@85010|Pseudonocardiales	201174|Actinobacteria	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
TLS3_k127_3713320_4	1120948.KB903218_gene2069	1.437e-60	211.0	COG3460@1|root,COG3460@2|Bacteria,2IKMJ@201174|Actinobacteria,4E4A8@85010|Pseudonocardiales	201174|Actinobacteria	Q	PFAM Phenylacetic acid degradation B	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
TLS3_k127_3713320_1	1120948.KB903218_gene2070	2.189e-192	604.0	COG3396@1|root,COG3396@2|Bacteria,2GMQ3@201174|Actinobacteria,4E0VZ@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM phenylacetate-CoA oxygenase, PaaG subunit	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
TLS3_k127_3713320_2	2074.JNYD01000001_gene6240	3.073e-158	516.0	COG0644@1|root,COG0644@2|Bacteria,2GM2M@201174|Actinobacteria	201174|Actinobacteria	C	FAD dependent oxidoreductase	srsC	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored
TLS3_k127_3713320_3	2074.JNYD01000001_gene6241	4.287e-76	275.0	COG1755@1|root,COG1755@2|Bacteria,2IG52@201174|Actinobacteria,4EAVJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	ko:K16168	-	-	-	-	ko00000,ko01008	-	-	-	ICMT
TLS3_k127_3713320_0	2074.JNYD01000001_gene6242	1.238e-194	614.0	COG3424@1|root,COG3424@2|Bacteria,2GV0U@201174|Actinobacteria,4E1NP@85010|Pseudonocardiales	201174|Actinobacteria	Q	naringenin-chalcone synthase	pks11	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006725,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009698,GO:0009699,GO:0009714,GO:0009715,GO:0009987,GO:0016020,GO:0016043,GO:0019438,GO:0019748,GO:0022607,GO:0032991,GO:0034081,GO:0042180,GO:0042181,GO:0042546,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901360,GO:1901362,GO:1901576	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
TLS3_k127_3713320_5	1134445.AJJM01000099_gene3593	4.719e-45	167.0	COG0644@1|root,COG0644@2|Bacteria,2GMH9@201174|Actinobacteria	201174|Actinobacteria	C	geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
TLS3_k127_3728761_2	1120948.KB903246_gene3249	3.439e-07	52.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4DXUB@85010|Pseudonocardiales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
TLS3_k127_3728761_0	994479.GL877881_gene6501	6.298e-152	502.0	COG0019@1|root,COG0019@2|Bacteria,2GIT5@201174|Actinobacteria,4E43V@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS3_k127_3728761_1	994479.GL877881_gene6502	8.19e-79	287.0	COG3836@1|root,COG3836@2|Bacteria,2HGEA@201174|Actinobacteria,4E0YB@85010|Pseudonocardiales	201174|Actinobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
TLS3_k127_3738320_3	1120948.KB903229_gene5280	4.44e-40	151.0	COG0438@1|root,COG0438@2|Bacteria,2I8FJ@201174|Actinobacteria,4EF27@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_3738320_4	1120948.KB903229_gene5280	2.705e-36	141.0	COG0438@1|root,COG0438@2|Bacteria,2I8FJ@201174|Actinobacteria,4EF27@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_3738320_1	1120948.KB903229_gene5281	6.947e-121	397.0	COG0859@1|root,COG0859@2|Bacteria,2IFJI@201174|Actinobacteria,4E39B@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
TLS3_k127_3738320_0	1120948.KB903229_gene5282	4.097e-160	509.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria,4E9PC@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_3738320_2	446471.Xcel_0077	6.344e-65	241.0	COG2197@1|root,COG2203@1|root,COG4585@1|root,COG2197@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria,2IBTN@201174|Actinobacteria	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GerE,HATPase_c,HisKA_3,Response_reg
TLS3_k127_3750556_0	1120948.KB903220_gene5	0.0	1276.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4E0TC@85010|Pseudonocardiales	201174|Actinobacteria	EQ	Hydantoinase B/oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
TLS3_k127_3750556_2	1120948.KB903220_gene6	2.752e-273	847.0	COG0654@1|root,COG0654@2|Bacteria,2GNZN@201174|Actinobacteria,4E20D@85010|Pseudonocardiales	201174|Actinobacteria	CH	FAD binding domain	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
TLS3_k127_3750556_1	1120948.KB903220_gene7	6.746e-287	889.0	COG1021@1|root,COG1021@2|Bacteria,2I2IR@201174|Actinobacteria,4DXX2@85010|Pseudonocardiales	201174|Actinobacteria	Q	AMP-binding enzyme C-terminal domain	-	-	2.7.7.58,6.3.2.14	ko:K02363	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R07644	RC00162,RC03046	ko00000,ko00001,ko01000,ko01008	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_3750556_4	1120948.KB903220_gene8	5.134e-123	407.0	COG3473@1|root,COG3473@2|Bacteria,2HRMA@201174|Actinobacteria,4E1YT@85010|Pseudonocardiales	201174|Actinobacteria	Q	Catalyzes the conversion of maleate to fumarate	maiA	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	-
TLS3_k127_3750556_6	1120948.KB903220_gene16	1.887e-115	390.0	COG1309@1|root,COG1309@2|Bacteria,2GKE2@201174|Actinobacteria,4E2V9@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_3750556_5	1120948.KB903220_gene17	2.011e-116	394.0	COG0346@1|root,COG0346@2|Bacteria,2H3HR@201174|Actinobacteria,4DYE5@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_3750556_8	1120948.KB903220_gene18	7.294e-42	156.0	2E9UG@1|root,3340C@2|Bacteria,2GQYP@201174|Actinobacteria,4E7A2@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3750556_3	1120948.KB903220_gene19	1.25e-212	671.0	COG2267@1|root,COG2267@2|Bacteria,2I3P3@201174|Actinobacteria,4E207@85010|Pseudonocardiales	201174|Actinobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3750556_7	1120948.KB903227_gene4836	1.46e-112	374.0	COG0668@1|root,COG0668@2|Bacteria,2HD92@201174|Actinobacteria,4E0HQ@85010|Pseudonocardiales	201174|Actinobacteria	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
TLS3_k127_3782611_2	1120948.KB903220_gene82	5.846e-162	512.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4DXGM@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
TLS3_k127_3782611_11	1120948.KB903220_gene81	1.2e-35	139.0	COG1359@1|root,COG1359@2|Bacteria,2I3RE@201174|Actinobacteria,4EF74@85010|Pseudonocardiales	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
TLS3_k127_3782611_12	103733.JNYO01000002_gene513	1.332e-10	66.0	2BIMD@1|root,32CUB@2|Bacteria,2GT5B@201174|Actinobacteria,4E6XQ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3782611_10	1278078.G419_17707	1.074e-42	166.0	COG0640@1|root,COG0640@2|Bacteria,2IMSD@201174|Actinobacteria,4G26E@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	smtB	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0044212,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K22298	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
TLS3_k127_3782611_7	1120948.KB903220_gene78	6.573e-63	230.0	COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria,4E2M3@85010|Pseudonocardiales	201174|Actinobacteria	P	Belongs to the Fur family	furB	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
TLS3_k127_3782611_0	2074.JNYD01000003_gene3556	3.481e-222	706.0	COG1292@1|root,COG1292@2|Bacteria,2GJX0@201174|Actinobacteria,4DXDK@85010|Pseudonocardiales	201174|Actinobacteria	U	Belongs to the BCCT transporter (TC 2.A.15) family	betP	-	-	ko:K05020	-	-	-	-	ko00000,ko02000	2.A.15.1.1,2.A.15.1.11	-	-	BCCT
TLS3_k127_3782611_9	1120948.KB903218_gene2119	1.835e-53	198.0	COG3689@1|root,COG3689@2|Bacteria,2GNFK@201174|Actinobacteria,4E2XB@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF1980)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1980
TLS3_k127_3782611_6	1123023.JIAI01000003_gene2595	3.844e-127	416.0	COG0701@1|root,COG0701@2|Bacteria,2GJQ0@201174|Actinobacteria,4DY2Z@85010|Pseudonocardiales	201174|Actinobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
TLS3_k127_3782611_8	1120948.KB903220_gene77	7.19e-60	231.0	2CA90@1|root,336GT@2|Bacteria,2IJI6@201174|Actinobacteria,4E3WW@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3782611_4	1120948.KB903220_gene76	1.376e-147	486.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4E05X@85010|Pseudonocardiales	201174|Actinobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.86,2.5.1.88	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	-	R06447,R09244,R09731	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
TLS3_k127_3782611_5	1120948.KB903220_gene75	4.384e-130	432.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4DYII@85010|Pseudonocardiales	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
TLS3_k127_3782611_3	1120948.KB903220_gene73	6.735e-158	505.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4DXE1@85010|Pseudonocardiales	201174|Actinobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
TLS3_k127_3782611_1	1120948.KB903220_gene72	5.418e-211	665.0	COG0579@1|root,COG0579@2|Bacteria,2GKFB@201174|Actinobacteria,4DX9F@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM FAD dependent oxidoreductase	lhgO	-	1.1.5.4	ko:K00116,ko:K15736	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO
TLS3_k127_3782611_13	675635.Psed_4484	3.556e-08	57.0	COG0295@1|root,COG0295@2|Bacteria,2IM42@201174|Actinobacteria,4E5GX@85010|Pseudonocardiales	201174|Actinobacteria	F	cytidine deaminase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3793935_5	1236902.ANAS01000004_gene3616	3.419e-24	117.0	COG0666@1|root,COG0666@2|Bacteria,2IIAC@201174|Actinobacteria,4EKBG@85012|Streptosporangiales	201174|Actinobacteria	T	Ankyrin repeats (many copies)	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4,Ank_5
TLS3_k127_3793935_2	1120948.KB903217_gene1140	1.839e-164	527.0	COG1524@1|root,COG1524@2|Bacteria,2GISU@201174|Actinobacteria,4E06D@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
TLS3_k127_3793935_0	994479.GL877880_gene3874	0.0	1075.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,4DZP0@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
TLS3_k127_3793935_3	1120948.KB903217_gene1145	9.993e-123	400.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4DY81@85010|Pseudonocardiales	201174|Actinobacteria	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	-	-	-	-	-	-	-	-	-	SIR2
TLS3_k127_3793935_1	1120948.KB903217_gene1148	3.667e-189	611.0	COG0312@1|root,COG0312@2|Bacteria,2GZPS@201174|Actinobacteria,4E1WV@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
TLS3_k127_3793935_4	426716.JOAJ01000003_gene3326	2.709e-102	334.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,4FWGN@85025|Nocardiaceae	201174|Actinobacteria	S	Putative modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
TLS3_k127_3799570_5	1500301.JQMF01000014_gene4642	8.798e-51	186.0	COG1028@1|root,COG1028@2|Bacteria,1PTQR@1224|Proteobacteria,2TQN4@28211|Alphaproteobacteria,4B95R@82115|Rhizobiaceae	28211|Alphaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_3799570_2	285514.JNWO01000001_gene4241	9.116e-114	371.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_3799570_6	73044.JNXP01000015_gene1652	1.346e-40	166.0	COG2606@1|root,COG2606@2|Bacteria,2IKUX@201174|Actinobacteria	201174|Actinobacteria	S	YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
TLS3_k127_3799570_3	208439.AJAP_24950	3.627e-109	373.0	COG0463@1|root,COG0463@2|Bacteria,2I2NK@201174|Actinobacteria,4E09C@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2
TLS3_k127_3799570_1	1464048.JNZS01000010_gene5208	3.813e-134	457.0	COG0438@1|root,COG0438@2|Bacteria,2I005@201174|Actinobacteria,4DHXP@85008|Micromonosporales	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_3799570_9	479431.Namu_4791	4.664e-07	58.0	COG1695@1|root,COG1695@2|Bacteria,2IQSE@201174|Actinobacteria,4EW7Q@85013|Frankiales	201174|Actinobacteria	K	PFAM transcriptional regulator PadR family protein	ywzG	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_3799570_10	1120948.KB903245_gene3523	0.0001259	48.0	COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria,4DYVN@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
TLS3_k127_3799570_0	1120948.KB903245_gene3522	9.097e-138	451.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,4E015@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
TLS3_k127_3799570_4	1120948.KB903244_gene2859	1.287e-61	220.0	COG0596@1|root,COG0596@2|Bacteria,2I3SN@201174|Actinobacteria,4EF94@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
TLS3_k127_3799570_7	1068978.AMETH_4910	3.781e-22	98.0	COG3369@1|root,COG3369@2|Bacteria,2GQTK@201174|Actinobacteria,4E6WH@85010|Pseudonocardiales	201174|Actinobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
TLS3_k127_3799570_8	1278078.G419_06322	1.045e-16	81.0	28INB@1|root,2Z8NQ@2|Bacteria,2GM2K@201174|Actinobacteria,4FV6I@85025|Nocardiaceae	201174|Actinobacteria	S	Iron-containing redox enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
TLS3_k127_3803645_7	1120948.KB903245_gene3443	1.96e-63	229.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4E3E1@85010|Pseudonocardiales	201174|Actinobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
TLS3_k127_3803645_3	1120948.KB903245_gene3444	1.59e-114	378.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4DXC4@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,tRNA_m1G_MT
TLS3_k127_3803645_6	1120948.KB903245_gene3445	7.588e-88	297.0	COG1285@1|root,COG1285@2|Bacteria,2GJF0@201174|Actinobacteria,4E37D@85010|Pseudonocardiales	201174|Actinobacteria	S	MgtC family	mgtC	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
TLS3_k127_3803645_9	1120948.KB903245_gene3446	5.839e-57	208.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4E2W5@85010|Pseudonocardiales	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
TLS3_k127_3803645_11	1120948.KB903245_gene3447	1.764e-36	148.0	COG1837@1|root,COG1837@2|Bacteria,2IQ4C@201174|Actinobacteria,4E5DG@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the UPF0109 family	-	GO:0008150,GO:0040007	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
TLS3_k127_3803645_10	1120948.KB903245_gene3448	6.798e-55	208.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4E3JW@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
TLS3_k127_3803645_5	1120948.KB903245_gene3449	4.226e-99	330.0	COG1540@1|root,COG1540@2|Bacteria,2GJA1@201174|Actinobacteria,4DXTK@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the UPF0271 (lamB) family	ycsF	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
TLS3_k127_3803645_4	266117.Rxyl_1058	3.819e-112	378.0	COG0477@1|root,COG0477@2|Bacteria,2I2QX@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08168,ko:K18926	-	M00704,M00715	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3.16,2.A.1.3.22,2.A.1.3.30,2.A.1.3.6	-	-	MFS_1
TLS3_k127_3803645_1	1120948.KB903245_gene3450	1.329e-157	537.0	COG1228@1|root,COG1228@2|Bacteria,2GKRZ@201174|Actinobacteria,4DZ8J@85010|Pseudonocardiales	201174|Actinobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
TLS3_k127_3803645_8	1209984.BN978_02596	1.653e-60	211.0	COG3801@1|root,COG3801@2|Bacteria,2IHP4@201174|Actinobacteria,239B5@1762|Mycobacteriaceae	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
TLS3_k127_3803645_0	1120948.KB903245_gene3452	9.006e-284	879.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4DXH6@85010|Pseudonocardiales	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
TLS3_k127_3803645_2	1206101.AZXC01000008_gene3035	3.074e-149	484.0	COG0654@1|root,COG0654@2|Bacteria,2GK88@201174|Actinobacteria	201174|Actinobacteria	CH	PFAM monooxygenase FAD-binding	-	-	-	ko:K16037	ko01051,ko01052,ko01130,map01051,map01052,map01130	-	R09855	RC02841	ko00000,ko00001	-	-	-	FAD_binding_3
TLS3_k127_3812118_0	1120948.KB903244_gene3039	1.354e-106	349.0	COG1351@1|root,COG1351@2|Bacteria,2HCNJ@201174|Actinobacteria,4DY6Z@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	GO:0000166,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0036094,GO:0040007,GO:0042083,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050797,GO:0070402,GO:0097159,GO:1901265,GO:1901363	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	iNJ661.Rv2754c	Thy1
TLS3_k127_3812118_2	1120948.KB903244_gene3040	4.224e-55	204.0	COG4226@1|root,COG4226@2|Bacteria,2II9R@201174|Actinobacteria,4E3QF@85010|Pseudonocardiales	201174|Actinobacteria	S	HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB
TLS3_k127_3812118_1	1120948.KB903244_gene3041	1.275e-61	226.0	COG3595@1|root,COG3595@2|Bacteria,2HIX2@201174|Actinobacteria,4DYUW@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
TLS3_k127_3812118_4	1120949.KB903311_gene667	3.224e-08	67.0	COG0583@1|root,COG0583@2|Bacteria,2GMDN@201174|Actinobacteria,4DF1F@85008|Micromonosporales	201174|Actinobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS3_k127_3812118_3	1120948.KB903244_gene3042	4.286e-16	77.0	COG0479@1|root,COG0479@2|Bacteria,2GJPS@201174|Actinobacteria,4DYEG@85010|Pseudonocardiales	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
TLS3_k127_3846149_5	1120948.KB903217_gene1215	5.739e-115	373.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4DYYV@85010|Pseudonocardiales	201174|Actinobacteria	F	PFAM AIR synthase related protein	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016882,GO:0044424,GO:0044444,GO:0044464	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
TLS3_k127_3846149_15	1120948.KB903217_gene1216	2.84e-27	114.0	2E3Y8@1|root,32YVA@2|Bacteria,2GXDI@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2945)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2945
TLS3_k127_3846149_17	1120948.KB903217_gene1217	1.76e-20	93.0	2EGRW@1|root,33AI2@2|Bacteria,2IQF3@201174|Actinobacteria,4E7DF@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3073)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3073
TLS3_k127_3846149_7	1120948.KB903217_gene1218	1.049e-96	327.0	2BPHM@1|root,32IA4@2|Bacteria,2GM2J@201174|Actinobacteria,4DXXF@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3846149_9	1120948.KB903217_gene1219	1.094e-77	273.0	2DP8R@1|root,32UKH@2|Bacteria,2IFBP@201174|Actinobacteria,4E378@85010|Pseudonocardiales	201174|Actinobacteria	-	-	amfC	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3846149_4	1120948.KB903217_gene1220	1.109e-118	391.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DZRE@85010|Pseudonocardiales	201174|Actinobacteria	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_3846149_1	1120948.KB903217_gene1221	6.622e-161	524.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,4DZ5B@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
TLS3_k127_3846149_11	1120948.KB903217_gene1222	1.781e-65	230.0	COG0735@1|root,COG0735@2|Bacteria,2IFHB@201174|Actinobacteria,4E3EB@85010|Pseudonocardiales	201174|Actinobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
TLS3_k127_3846149_12	1120948.KB903217_gene1223	1.999e-64	231.0	COG3599@1|root,COG3599@2|Bacteria,2H7PF@201174|Actinobacteria,4ECIA@85010|Pseudonocardiales	201174|Actinobacteria	D	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3846149_8	103733.JNYO01000004_gene7736	9.122e-86	295.0	COG1984@1|root,COG1984@2|Bacteria,2GITH@201174|Actinobacteria,4DXP4@85010|Pseudonocardiales	201174|Actinobacteria	E	Allophanate hydrolase subunit 2	kipA	-	-	-	-	-	-	-	-	-	-	-	CT_A_B,CT_C_D
TLS3_k127_3846149_13	330084.JNYZ01000009_gene6486	5.86e-56	212.0	COG2049@1|root,COG2049@2|Bacteria,2I2R8@201174|Actinobacteria,4E32G@85010|Pseudonocardiales	201174|Actinobacteria	E	Allophanate hydrolase subunit 1	kipI	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
TLS3_k127_3846149_6	1120948.KB903217_gene1225	2.639e-105	345.0	COG4044@1|root,COG4044@2|Bacteria,2GKGF@201174|Actinobacteria,4DZEZ@85010|Pseudonocardiales	201174|Actinobacteria	S	May play a role in the intracellular transport of hydrophobic ligands	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1794
TLS3_k127_3846149_14	1120948.KB903217_gene1227	9.64e-46	171.0	2E36U@1|root,32Y6I@2|Bacteria,2IM2G@201174|Actinobacteria,4E5UM@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1416)	sseC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1416
TLS3_k127_3846149_0	1120948.KB903217_gene1228	9.862e-168	532.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria,4E0UA@85010|Pseudonocardiales	201174|Actinobacteria	P	Sulfurtransferase	cysA2	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
TLS3_k127_3846149_16	1120948.KB903217_gene1229	2.283e-24	111.0	COG0526@1|root,COG0526@2|Bacteria,2IKMI@201174|Actinobacteria,4E4HC@85010|Pseudonocardiales	201174|Actinobacteria	CO	Thioredoxin	thiX	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
TLS3_k127_3846149_3	1120948.KB903217_gene1230	1.518e-138	445.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4DXD7@85010|Pseudonocardiales	201174|Actinobacteria	KT	Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	glnR	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
TLS3_k127_3846149_10	211114.JOEF01000002_gene4011	8.11e-77	280.0	COG0454@1|root,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,4DY2M@85010|Pseudonocardiales	201174|Actinobacteria	K	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol	mshD	GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
TLS3_k127_3846149_2	1120948.KB903217_gene1232	3.636e-149	481.0	COG0226@1|root,COG0226@2|Bacteria,2GJXD@201174|Actinobacteria,4DXS7@85010|Pseudonocardiales	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	GO:0002682,GO:0002683,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0015698,GO:0016020,GO:0016036,GO:0030312,GO:0031347,GO:0031348,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035821,GO:0040007,GO:0042594,GO:0043207,GO:0044003,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0044464,GO:0045088,GO:0045824,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0071496,GO:0071944,GO:0075136,GO:0080134	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
TLS3_k127_3847585_6	2074.JNYD01000052_gene1562	1.459e-89	306.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4DZ4E@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
TLS3_k127_3847585_3	1068978.AMETH_2250	2.679e-157	504.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4DXUF@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone	fgd	-	1.1.98.2	ko:K15510	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
TLS3_k127_3847585_5	1120948.KB903245_gene3600	7.788e-96	323.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4E0B2@85010|Pseudonocardiales	201174|Actinobacteria	F	nucleoside hydrolase	rihA	-	-	ko:K01250	-	-	-	-	ko00000,ko01000	-	-	-	IU_nuc_hydro
TLS3_k127_3847585_4	1120948.KB903222_gene572	1.338e-108	353.0	COG0328@1|root,COG0328@2|Bacteria,2GK53@201174|Actinobacteria,4E30W@85010|Pseudonocardiales	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF4440,RNase_H
TLS3_k127_3847585_2	1120948.KB903218_gene2051	2.559e-158	509.0	COG0477@1|root,COG0477@2|Bacteria,2GKVX@201174|Actinobacteria,4EA2J@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_3847585_15	1211815.CBYP010000050_gene545	1.349e-30	130.0	COG2172@1|root,COG2172@2|Bacteria,2GPWS@201174|Actinobacteria,4EWC8@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
TLS3_k127_3847585_0	1120948.KB903217_gene1250	1.315e-208	651.0	COG1063@1|root,COG1063@2|Bacteria,2IA6Q@201174|Actinobacteria,4E40G@85010|Pseudonocardiales	201174|Actinobacteria	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_3847585_1	1120948.KB903217_gene1677	1.146e-195	617.0	COG2141@1|root,COG2141@2|Bacteria,2IC36@201174|Actinobacteria,4DZRA@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_3847585_7	2074.JNYD01000011_gene149	1.979e-86	294.0	COG0596@1|root,COG0596@2|Bacteria,2GNIR@201174|Actinobacteria,4E3CJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
TLS3_k127_3847585_14	1120948.KB903218_gene2155	3.191e-42	166.0	COG0454@1|root,COG0456@2|Bacteria,2IMKB@201174|Actinobacteria,4E6GP@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03827	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
TLS3_k127_3847585_12	1120948.KB903218_gene2158	1.583e-54	202.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	pimE	GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.7.53,3.6.1.13,3.6.1.55	ko:K01515,ko:K03574,ko:K13669,ko:K19710	ko00230,map00230	-	R00126,R01054,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000,ko01003,ko03400	-	GT87	-	GT87,NUDIX
TLS3_k127_3847585_18	196162.Noca_1532	0.0005231	44.0	COG2059@1|root,COG2059@2|Bacteria,2IB69@201174|Actinobacteria,4DNBH@85009|Propionibacteriales	201174|Actinobacteria	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
TLS3_k127_3847585_10	1068978.AMETH_1719	5.363e-71	258.0	COG0515@1|root,COG0515@2|Bacteria,2IAZC@201174|Actinobacteria,4DXAZ@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TLS3_k127_3847585_17	1306174.JODP01000020_gene434	0.000179	52.0	COG2346@1|root,COG2346@2|Bacteria,2GMG5@201174|Actinobacteria	201174|Actinobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	ABM,Bac_globin
TLS3_k127_3847585_16	710685.MycrhN_5902	1.488e-28	132.0	2DMMA@1|root,32SDH@2|Bacteria,2IM8C@201174|Actinobacteria,23AE5@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
TLS3_k127_3847585_8	103733.JNYO01000057_gene963	1.364e-73	250.0	COG1846@1|root,COG1846@2|Bacteria,2IJ3N@201174|Actinobacteria,4DZ0V@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
TLS3_k127_3847585_11	479435.Kfla_4476	3.839e-60	213.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4DTDV@85009|Propionibacteriales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
TLS3_k127_3854212_4	66377.JOBH01000006_gene229	9.673e-50	182.0	COG1024@1|root,COG1024@2|Bacteria,2GKC4@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
TLS3_k127_3854212_0	1394178.AWOO02000021_gene7271	2.466e-246	763.0	COG1960@1|root,COG1960@2|Bacteria,2GJX5@201174|Actinobacteria,4EQRU@85012|Streptosporangiales	201174|Actinobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	fadE12_3	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_3854212_1	28042.GU90_03955	8.349e-178	595.0	COG3173@1|root,COG3173@2|Bacteria,2HU7E@201174|Actinobacteria,4DYKS@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
TLS3_k127_3854212_2	1123024.AUII01000006_gene4554	6.595e-83	290.0	COG1309@1|root,COG1309@2|Bacteria,2GMNZ@201174|Actinobacteria,4E3N6@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_3854212_3	1123023.JIAI01000001_gene6398	3.979e-77	286.0	COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria,4DY55@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
TLS3_k127_3859235_1	1169161.KB897731_gene335	1.896e-58	207.0	COG0492@1|root,COG0492@2|Bacteria,2GIXN@201174|Actinobacteria	201174|Actinobacteria	O	pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
TLS3_k127_3859235_2	512565.AMIS_56350	1.798e-48	189.0	COG0492@1|root,COG2227@1|root,COG0492@2|Bacteria,COG2227@2|Bacteria,2GIXN@201174|Actinobacteria,4DAND@85008|Micromonosporales	201174|Actinobacteria	O	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25,Pyr_redox_2
TLS3_k127_3859235_0	1120948.KB903229_gene5300	9.568e-154	490.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZBV@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	fadD36	-	-	ko:K12429,ko:K18662	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_3860693_3	593907.Celgi_2305	2.042e-18	84.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4F29M@85016|Cellulomonadaceae	201174|Actinobacteria	L	ATP dependent DNA ligase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
TLS3_k127_3860693_0	1120948.KB903244_gene2805	1.638e-80	281.0	2F1BY@1|root,33UCU@2|Bacteria,2H92I@201174|Actinobacteria,4E4PN@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3860693_1	1120948.KB903244_gene2804	4.638e-73	250.0	2DV89@1|root,33UM5@2|Bacteria,2GQ03@201174|Actinobacteria,4EF3U@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3860693_2	1120948.KB903244_gene2803	3.801e-38	151.0	COG1302@1|root,COG1302@2|Bacteria,2GU1H@201174|Actinobacteria,4E76A@85010|Pseudonocardiales	201174|Actinobacteria	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
TLS3_k127_3860693_5	247156.NFA_23400	0.0001765	46.0	2EGEG@1|root,33A6G@2|Bacteria,2HIGE@201174|Actinobacteria,4G40G@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3866097_0	1120948.KB903218_gene1995	7.053e-226	715.0	COG0439@1|root,COG4799@1|root,COG0439@2|Bacteria,COG4799@2|Bacteria,2I2S0@201174|Actinobacteria,4DZ0F@85010|Pseudonocardiales	201174|Actinobacteria	I	Biotin carboxylase C-terminal domain	accA3_1	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
TLS3_k127_3866097_2	323848.Nmul_A2249	1.53e-21	96.0	COG3360@1|root,COG3360@2|Bacteria,1PW6C@1224|Proteobacteria,2VXDE@28216|Betaproteobacteria,373H6@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
TLS3_k127_3866097_1	2074.JNYD01000030_gene6655	3.965e-86	308.0	COG1289@1|root,COG1289@2|Bacteria,2GN9U@201174|Actinobacteria,4E642@85010|Pseudonocardiales	201174|Actinobacteria	S	Fusaric acid resistance protein-like	yccS_1	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
TLS3_k127_3867365_0	1120948.KB903218_gene2085	0.0	1039.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4E0F3@85010|Pseudonocardiales	201174|Actinobacteria	G	PEP-utilising enzyme, mobile domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
TLS3_k127_3867365_1	1120948.KB903229_gene5146	1.134e-114	380.0	COG2114@1|root,COG2114@2|Bacteria,2GJRI@201174|Actinobacteria,4DZBF@85010|Pseudonocardiales	201174|Actinobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
TLS3_k127_3869497_2	1449976.KALB_2116	7.434e-06	53.0	COG2375@1|root,COG2375@2|Bacteria,2GK5X@201174|Actinobacteria,4DX60@85010|Pseudonocardiales	201174|Actinobacteria	P	Siderophore-interacting protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_9,SIP
TLS3_k127_3869497_0	1120948.KB903246_gene3249	6.762e-153	503.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4DXUB@85010|Pseudonocardiales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
TLS3_k127_3869497_1	994479.GL877881_gene6501	8.832e-15	74.0	COG0019@1|root,COG0019@2|Bacteria,2GIT5@201174|Actinobacteria,4E43V@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS3_k127_3870905_1	1120948.KB903217_gene1699	8.844e-118	387.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4DX9A@85010|Pseudonocardiales	201174|Actinobacteria	L	Hydrolase, TatD family	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
TLS3_k127_3870905_0	1120948.KB903217_gene1698	1.046e-227	707.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4E07J@85010|Pseudonocardiales	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
TLS3_k127_3875696_8	1120948.KB903217_gene1623	1.053e-75	257.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,4DZ1S@85010|Pseudonocardiales	201174|Actinobacteria	S	TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
TLS3_k127_3875696_4	2074.JNYD01000001_gene5943	4.88e-111	366.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4DYJ0@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_3875696_2	1120948.KB903217_gene1622	7.705e-191	601.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4DXE7@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Aminotransferase class I and II	dapC	-	2.6.1.1,2.6.1.17	ko:K00812,ko:K14267	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016	R00355,R00694,R00734,R00896,R02433,R02619,R04475,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_3875696_0	1120948.KB903217_gene1617	2.194e-305	943.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4DXUU@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
TLS3_k127_3875696_5	1120948.KB903217_gene1616	1.048e-84	286.0	COG1695@1|root,COG1695@2|Bacteria,2IJQK@201174|Actinobacteria,4E561@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_3875696_1	1120948.KB903217_gene1615	8.115e-214	681.0	COG0654@1|root,COG0654@2|Bacteria,2GJS5@201174|Actinobacteria,4E1VQ@85010|Pseudonocardiales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,NAD_binding_8
TLS3_k127_3875696_6	1206725.BAFU01000232_gene3073	4.542e-84	302.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4FY2Z@85025|Nocardiaceae	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
TLS3_k127_3875696_9	1120950.KB892775_gene1205	7.374e-62	218.0	COG1309@1|root,COG1309@2|Bacteria,2GKHT@201174|Actinobacteria,4DWUC@85009|Propionibacteriales	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
TLS3_k127_3875696_7	1206725.BAFU01000039_gene1940	3.344e-83	282.0	2AEJC@1|root,314EV@2|Bacteria,2GMTI@201174|Actinobacteria,4FWKX@85025|Nocardiaceae	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
TLS3_k127_3875696_3	1380393.JHVP01000004_gene750	4.441e-134	445.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4ETWT@85013|Frankiales	201174|Actinobacteria	C	Iron-containing alcohol dehydrogenase	-	-	1.3.1.32	ko:K00217	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	-	R02988,R02989,R05355,R06848,R07781,R09137,R09138,R09223,R09224	RC00107,RC01335,RC01689,RC02442	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
TLS3_k127_3875696_10	1463825.JNXC01000007_gene1008	1.522e-57	204.0	COG1690@1|root,COG1690@2|Bacteria,2GIUP@201174|Actinobacteria,4E0F5@85010|Pseudonocardiales	201174|Actinobacteria	L	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
TLS3_k127_3879730_2	1120948.KB903229_gene5378	1.879e-101	344.0	COG4977@1|root,COG4977@2|Bacteria,2GIRA@201174|Actinobacteria,4DXBW@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
TLS3_k127_3879730_0	1120948.KB903229_gene5379	9.124e-210	671.0	COG2271@1|root,COG2271@2|Bacteria,2GVNB@201174|Actinobacteria,4DXI6@85010|Pseudonocardiales	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_3879730_4	634956.Geoth_1638	4.038e-34	141.0	COG1414@1|root,COG1414@2|Bacteria,1W784@1239|Firmicutes,4ICFU@91061|Bacilli,1WE99@129337|Geobacillus	91061|Bacilli	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
TLS3_k127_3879730_1	1120948.KB903217_gene1271	7.016e-162	520.0	COG0477@1|root,COG2814@2|Bacteria,2I2P6@201174|Actinobacteria,4EF5Z@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	mdfA	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_3879730_3	1120948.KB903240_gene4144	9.84e-56	196.0	COG0574@1|root,COG0574@2|Bacteria,2HEK7@201174|Actinobacteria,4E852@85010|Pseudonocardiales	201174|Actinobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N
TLS3_k127_3887108_3	1120948.KB903243_gene2534	9.694e-142	451.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4DYQ2@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
TLS3_k127_3887108_1	675635.Psed_0614	4.729e-204	643.0	COG0415@1|root,COG0415@2|Bacteria,2GJXU@201174|Actinobacteria,4DZI6@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
TLS3_k127_3887108_2	1120948.KB903219_gene633	1.065e-142	460.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4DXIG@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
TLS3_k127_3887108_4	1120948.KB903243_gene2532	8.927e-125	415.0	COG1668@1|root,COG1668@2|Bacteria,2I9MY@201174|Actinobacteria,4DYBQ@85010|Pseudonocardiales	201174|Actinobacteria	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
TLS3_k127_3887108_5	1120948.KB903243_gene2531	1.749e-122	412.0	COG4152@1|root,COG4152@2|Bacteria,2I2DK@201174|Actinobacteria,4DX3X@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
TLS3_k127_3887108_7	1449976.KALB_653	1.71e-101	352.0	COG2105@1|root,COG2105@2|Bacteria,2HVR7@201174|Actinobacteria,4DYPG@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
TLS3_k127_3887108_6	1120948.KB903243_gene2528	1.373e-102	337.0	COG0491@1|root,COG0491@2|Bacteria,2GJ7I@201174|Actinobacteria,4E2F5@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_3887108_0	1120948.KB903243_gene2527	7.86e-224	695.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4DZ8N@85010|Pseudonocardiales	201174|Actinobacteria	C	formaldehyde dehydrogenase	adhC	-	1.1.1.306	ko:K00153	-	-	R09129,R10301	RC00069,RC01715	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_3906396_2	1123023.JIAI01000001_gene6414	1.548e-78	273.0	COG2508@1|root,COG2508@2|Bacteria,2I8HD@201174|Actinobacteria,4E4XX@85010|Pseudonocardiales	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
TLS3_k127_3906396_1	1211815.CBYP010000073_gene3633	3.044e-99	332.0	COG2301@1|root,COG2301@2|Bacteria,2H1SS@201174|Actinobacteria	201174|Actinobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
TLS3_k127_3906396_0	1146883.BLASA_3383	8.37e-127	429.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	5.1.3.2	ko:K01784,ko:K20534	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Epimerase,Glycos_transf_2
TLS3_k127_3906396_4	526225.Gobs_3645	1.15e-68	259.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_3906396_3	526225.Gobs_3642	4.056e-76	281.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_3921145_0	1120948.KB903246_gene3340	4.6e-228	727.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria,4DY50@85010|Pseudonocardiales	201174|Actinobacteria	E	ABC-type dipeptide transport system	lpqW	GO:0005575,GO:0005576,GO:0005623,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0040007,GO:0042597,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
TLS3_k127_3921145_1	446462.Amir_0755	1.59e-23	102.0	COG0494@1|root,COG0494@2|Bacteria,2I2GY@201174|Actinobacteria,4E317@85010|Pseudonocardiales	201174|Actinobacteria	L	pfam nudix	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
TLS3_k127_3940948_0	1120948.KB903223_gene198	0.0	1240.0	COG0768@1|root,COG0772@1|root,COG0768@2|Bacteria,COG0772@2|Bacteria,2GJ61@201174|Actinobacteria,4E550@85010|Pseudonocardiales	201174|Actinobacteria	DM	PFAM penicillin-binding protein transpeptidase	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	FTSW_RODA_SPOVE,PBP_dimer,Transpeptidase
TLS3_k127_3940948_1	1120948.KB903217_gene1382	1.397e-139	454.0	COG0812@1|root,COG0812@2|Bacteria,2GIV2@201174|Actinobacteria,4DYMR@85010|Pseudonocardiales	201174|Actinobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
TLS3_k127_3940948_7	1463825.JNXC01000001_gene5996	1.71e-38	155.0	2DQ4E@1|root,334PH@2|Bacteria,2I51N@201174|Actinobacteria,4EDSU@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2505)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2505
TLS3_k127_3940948_2	675635.Psed_0593	1.445e-116	391.0	COG0788@1|root,COG0788@2|Bacteria,2GM0G@201174|Actinobacteria,4E14G@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
TLS3_k127_3940948_4	1120948.KB903217_gene1379	1.079e-74	262.0	COG2606@1|root,COG2606@2|Bacteria,2GKUX@201174|Actinobacteria,4E2QX@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM YbaK prolyl-tRNA synthetases associated domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
TLS3_k127_3940948_10	1120948.KB903217_gene1378	1.046e-31	135.0	2EHMU@1|root,33BDI@2|Bacteria,2HM2X@201174|Actinobacteria,4E6QM@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2516)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2516
TLS3_k127_3940948_3	1120948.KB903217_gene1377	8.557e-89	308.0	2EBKM@1|root,335M1@2|Bacteria,2I5HJ@201174|Actinobacteria,4E38F@85010|Pseudonocardiales	201174|Actinobacteria	S	Heparin-binding hemagglutinin	hbhA	GO:0003674,GO:0005488,GO:0005515,GO:0005539,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0007155,GO:0007157,GO:0008150,GO:0008201,GO:0009986,GO:0016020,GO:0022610,GO:0030100,GO:0030312,GO:0032879,GO:0035821,GO:0042802,GO:0043167,GO:0043168,GO:0044003,GO:0044068,GO:0044077,GO:0044078,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045807,GO:0048259,GO:0048260,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051701,GO:0051704,GO:0051817,GO:0060627,GO:0065007,GO:0071944,GO:0097367,GO:0098609,GO:0098742,GO:1901681	-	ko:K16645	-	-	-	-	ko00000,ko00536	-	-	-	-
TLS3_k127_3940948_6	1120948.KB903217_gene1376	2.047e-53	192.0	COG1396@1|root,COG1396@2|Bacteria,2IKVI@201174|Actinobacteria,4E4CI@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Helix-turn-helix	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
TLS3_k127_3940948_8	2074.JNYD01000029_gene7175	2.938e-36	141.0	COG0239@1|root,COG0239@2|Bacteria,2IKM1@201174|Actinobacteria,4E6R9@85010|Pseudonocardiales	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
TLS3_k127_3940948_9	675635.Psed_0586	6.211e-32	134.0	COG0239@1|root,COG0239@2|Bacteria,2IKWG@201174|Actinobacteria,4E5N2@85010|Pseudonocardiales	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB1	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
TLS3_k127_3940948_5	1120948.KB903217_gene1373	6.536e-61	211.0	COG2733@1|root,COG2733@2|Bacteria,2GKGM@201174|Actinobacteria,4DYTZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
TLS3_k127_3944763_11	1120948.KB903247_gene4645	3.872e-22	97.0	COG1576@1|root,COG1576@2|Bacteria,2IGAN@201174|Actinobacteria,4E2Y6@85010|Pseudonocardiales	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
TLS3_k127_3944763_9	1240349.ANGC01000024_gene3562	1.761e-40	158.0	COG3832@1|root,COG3832@2|Bacteria,2IKZ7@201174|Actinobacteria,4G29U@85025|Nocardiaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_3944763_4	1120948.KB903220_gene128	7.724e-106	362.0	COG1024@1|root,COG1024@2|Bacteria,2I9BK@201174|Actinobacteria,4DXNQ@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
TLS3_k127_3944763_12	44060.JODL01000020_gene4887	5.697e-20	91.0	2E388@1|root,32Y7X@2|Bacteria,2GQYZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3944763_7	1120948.KB903243_gene2371	2.53e-87	294.0	COG0726@1|root,COG0726@2|Bacteria,2IH37@201174|Actinobacteria	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
TLS3_k127_3944763_10	1120948.KB903229_gene5063	3.723e-35	139.0	2E6NT@1|root,33198@2|Bacteria,2IFTP@201174|Actinobacteria,4E75D@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_3944763_8	1120948.KB903246_gene3248	9.401e-63	222.0	2DNP7@1|root,32YDT@2|Bacteria,2GR8Q@201174|Actinobacteria,4E79A@85010|Pseudonocardiales	201174|Actinobacteria	S	Family of unknown function (DUF5313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5313
TLS3_k127_3944763_5	2074.JNYD01000016_gene4197	1.818e-99	341.0	COG2186@1|root,COG2186@2|Bacteria,2INJC@201174|Actinobacteria,4EB0H@85010|Pseudonocardiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
TLS3_k127_3944763_6	2074.JNYD01000016_gene4200	2.561e-92	305.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,4DZ99@85010|Pseudonocardiales	201174|Actinobacteria	I	MaoC like domain	-	-	4.2.1.56	ko:K18290	ko00660,map00660	-	R02491	RC00730	ko00000,ko00001,ko01000	-	-	-	MaoC_dehydratas
TLS3_k127_3944763_0	675635.Psed_6733	1.761e-215	683.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4E8WS@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
TLS3_k127_3944763_1	2074.JNYD01000016_gene4202	1.781e-213	669.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4EA75@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_3944763_3	675635.Psed_6205	5.644e-177	579.0	COG0154@1|root,COG0154@2|Bacteria,2H36F@201174|Actinobacteria	201174|Actinobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
TLS3_k127_3944763_2	675635.Psed_6202	8.455e-202	635.0	COG2141@1|root,COG2141@2|Bacteria,2I9ZP@201174|Actinobacteria,4E2Z9@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	rutA	-	1.14.99.46	ko:K09018	ko00240,ko01100,map00240,map01100	-	R09936	RC02732	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
TLS3_k127_3947563_4	1123023.JIAI01000003_gene3042	2.475e-34	138.0	COG0790@1|root,COG0790@2|Bacteria,2GKCE@201174|Actinobacteria,4E7DX@85010|Pseudonocardiales	201174|Actinobacteria	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1,TPR_10,TPR_16,TPR_4
TLS3_k127_3947563_1	1120948.KB903243_gene2299	2.424e-105	366.0	COG1091@1|root,COG1091@2|Bacteria,2GNY8@201174|Actinobacteria,4DXT0@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rmlD	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
TLS3_k127_3947563_0	1120948.KB903243_gene2300	7.035e-177	574.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4DYHE@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
TLS3_k127_3947563_2	1123024.AUII01000005_gene2260	1.189e-71	265.0	COG0318@1|root,COG0318@2|Bacteria,2GIX4@201174|Actinobacteria,4EF7W@85010|Pseudonocardiales	201174|Actinobacteria	IQ	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
TLS3_k127_3947563_3	570268.ANBB01000008_gene4662	4.709e-48	192.0	COG2755@1|root,COG2755@2|Bacteria,2GM52@201174|Actinobacteria,4EQ41@85012|Streptosporangiales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_3
TLS3_k127_3951835_0	1120948.KB903219_gene736	0.0	1015.0	COG1216@1|root,COG1216@2|Bacteria,2GM9N@201174|Actinobacteria,4DXNF@85010|Pseudonocardiales	201174|Actinobacteria	NU	PFAM Glycosyl transferase family 2	glfT	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0008610,GO:0008653,GO:0008921,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009273,GO:0009987,GO:0010383,GO:0016020,GO:0016043,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0022607,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0035250,GO:0035496,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0046483,GO:0052573,GO:0055086,GO:0070589,GO:0070592,GO:0071554,GO:0071555,GO:0071704,GO:0071766,GO:0071769,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901576,GO:1903509	2.4.1.288	ko:K16650	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	iNJ661.Rv3808c	Glyco_tranf_2_3
TLS3_k127_3974963_3	1120948.KB903219_gene673	7.958e-88	294.0	COG1528@1|root,COG1528@2|Bacteria,2IG5S@201174|Actinobacteria,4E2T6@85010|Pseudonocardiales	201174|Actinobacteria	P	Iron-storage protein	bfrB	GO:0001666,GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0030312,GO:0033212,GO:0033214,GO:0036293,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051235,GO:0051238,GO:0051409,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070482,GO:0071944,GO:0097577,GO:0098771	1.16.3.1	ko:K22336	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
TLS3_k127_3974963_0	1120948.KB903219_gene675	2e-180	575.0	COG4097@1|root,COG4097@2|Bacteria,2H9AX@201174|Actinobacteria,4EAJ7@85010|Pseudonocardiales	201174|Actinobacteria	P	FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
TLS3_k127_3974963_2	1120948.KB903219_gene676	2.515e-105	362.0	COG0500@1|root,COG2226@2|Bacteria,2HFM8@201174|Actinobacteria,4DYRC@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	crtT	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
TLS3_k127_3974963_1	1120948.KB903219_gene677	1.925e-131	422.0	COG4638@1|root,COG4638@2|Bacteria,2I2DT@201174|Actinobacteria,4DYBY@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM Rieske 2Fe-2S domain	crtV	-	-	-	-	-	-	-	-	-	-	-	Rieske
TLS3_k127_4011704_4	1089545.KB913037_gene533	3.12e-74	270.0	COG1672@1|root,COG2197@1|root,COG1672@2|Bacteria,COG2197@2|Bacteria,2I3QJ@201174|Actinobacteria,4EF66@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_4011704_3	101510.RHA1_ro03479	3.412e-122	398.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4FZ2U@85025|Nocardiaceae	201174|Actinobacteria	C	Cysteine-rich domain	lutA	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
TLS3_k127_4011704_0	1120948.KB903229_gene5121	3.479e-251	797.0	COG1139@1|root,COG1139@2|Bacteria,2GJDR@201174|Actinobacteria,4DZA8@85010|Pseudonocardiales	201174|Actinobacteria	C	(4Fe-4S) cluster-containing protein	lutB	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
TLS3_k127_4011704_5	1120948.KB903229_gene5122	1.014e-72	273.0	COG1556@1|root,COG1556@2|Bacteria,2GNUJ@201174|Actinobacteria,4E2R1@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Uncharacterised ACR, YkgG family COG1556	lutC	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
TLS3_k127_4011704_1	1123024.AUII01000011_gene4432	5.978e-216	702.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD13_1	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_4011704_2	1123024.AUII01000011_gene4433	5.253e-163	522.0	COG1735@1|root,COG1735@2|Bacteria,2GMZ6@201174|Actinobacteria,4DYB9@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotriesterase family	php	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
TLS3_k127_4011704_8	1125971.ASJB01000015_gene5575	2.37e-24	108.0	COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria,4E5CC@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
TLS3_k127_4011704_9	593907.Celgi_0200	5.587e-21	103.0	COG3832@1|root,COG3832@2|Bacteria,2H898@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_4011704_6	1123319.AUBE01000011_gene4536	3.627e-34	138.0	COG4106@1|root,COG4106@2|Bacteria,2I3M6@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_4011704_7	2074.JNYD01000001_gene5907	8.924e-27	124.0	COG1533@1|root,COG1533@2|Bacteria,2GJ2F@201174|Actinobacteria,4DYVS@85010|Pseudonocardiales	201174|Actinobacteria	L	Radical SAM	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
TLS3_k127_4018018_0	1120948.KB903231_gene4730	1.584e-72	256.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4E0UI@85010|Pseudonocardiales	201174|Actinobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
TLS3_k127_4018018_1	1120948.KB903231_gene4731	1.376e-15	79.0	COG1040@1|root,COG1040@2|Bacteria,2I9PA@201174|Actinobacteria,4E5ME@85010|Pseudonocardiales	201174|Actinobacteria	S	phosphoribosyltransferase	pyrE_1	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
TLS3_k127_4019174_5	1236902.ANAS01000031_gene2789	1.074e-17	84.0	2C6FT@1|root,334HA@2|Bacteria,2HCTI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4019174_3	1120948.KB903217_gene819	9.709e-54	197.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4E2NI@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS3_k127_4019174_0	1289387.AUKW01000023_gene2965	5.617e-228	715.0	COG0591@1|root,COG0591@2|Bacteria,2GJ5E@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
TLS3_k127_4019174_4	1121385.AQXW01000004_gene3271	9.398e-19	96.0	2DRIG@1|root,33BY1@2|Bacteria,2GZU5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4019174_2	1289387.AUKW01000023_gene2962	3.617e-66	233.0	COG1802@1|root,COG1802@2|Bacteria,2GMI2@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
TLS3_k127_4019174_1	1120948.KB903246_gene3263	9.383e-121	404.0	COG0726@1|root,COG1215@1|root,COG1835@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,COG1835@2|Bacteria,2GJCE@201174|Actinobacteria,4DZV9@85010|Pseudonocardiales	201174|Actinobacteria	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3,Glyco_tranf_2_3,Polysacc_deac_1
TLS3_k127_4026487_1	1120948.KB903245_gene3621	3.759e-202	642.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4DZRD@85010|Pseudonocardiales	201174|Actinobacteria	C	Cytochrome bd-type quinol oxidase, subunit 1	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
TLS3_k127_4026487_6	1120948.KB903245_gene3622	2.353e-53	191.0	COG3682@1|root,COG3682@2|Bacteria,2IIIT@201174|Actinobacteria,4E5H4@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Penicillinase repressor	blaI	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
TLS3_k127_4026487_3	1120948.KB903245_gene3623	7.682e-109	359.0	COG0501@1|root,COG0501@2|Bacteria,2GM27@201174|Actinobacteria,4E49H@85010|Pseudonocardiales	201174|Actinobacteria	O	Zn-dependent protease with chaperone function	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
TLS3_k127_4026487_2	1179773.BN6_73080	2.487e-136	450.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4DZZ0@85010|Pseudonocardiales	201174|Actinobacteria	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
TLS3_k127_4026487_4	1123023.JIAI01000013_gene3948	1.9e-68	235.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,4E3HX@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
TLS3_k127_4026487_0	1120948.KB903245_gene3626	6.613e-262	838.0	COG0604@1|root,COG0604@2|Bacteria,2GKFF@201174|Actinobacteria,4DZDX@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.3.1.86	ko:K17829	ko00650,ko01120,ko01130,ko01200,map00650,map01120,map01130,map01200	-	R09738	RC00076	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_4026487_5	1120948.KB903245_gene3627	1.495e-53	199.0	COG1196@1|root,COG1196@2|Bacteria,2IIMZ@201174|Actinobacteria,4DYDX@85010|Pseudonocardiales	201174|Actinobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DivIVA
TLS3_k127_4029666_2	675635.Psed_2366	1.35e-57	217.0	COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria,4DYPU@85010|Pseudonocardiales	201174|Actinobacteria	S	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine	egtD	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
TLS3_k127_4029666_1	66377.JOBH01000002_gene732	2.875e-73	260.0	COG4340@1|root,COG4340@2|Bacteria,2I90Z@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	2OG-Fe_Oxy_2
TLS3_k127_4029666_0	1150864.MILUP08_43964	4.705e-94	310.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4D9JQ@85008|Micromonosporales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS3_k127_4032647_2	350058.Mvan_1929	4.952e-195	631.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,235YH@1762|Mycobacteriaceae	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_4032647_4	745014.OMB55_00002960	3.672e-36	146.0	COG1296@1|root,COG1296@2|Bacteria	2|Bacteria	E	L-valine transmembrane transporter activity	azlC	-	-	-	-	-	-	-	-	-	-	-	AzlC
TLS3_k127_4032647_3	2074.JNYD01000023_gene1340	6.209e-58	217.0	COG2120@1|root,COG2120@2|Bacteria,2IDT2@201174|Actinobacteria,4EBAF@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
TLS3_k127_4032647_1	1120948.KB903224_gene321	3.181e-208	654.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4DYFG@85010|Pseudonocardiales	201174|Actinobacteria	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.202	ko:K00086,ko:K11440	ko00260,ko00561,ko00640,ko01100,map00260,map00561,map00640,map01100	M00555	R02377,R03119,R08557,R08558	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Fe-ADH
TLS3_k127_4032647_0	1120948.KB903224_gene320	2.929e-217	683.0	COG4585@1|root,COG4585@2|Bacteria,2I8I8@201174|Actinobacteria,4E17E@85010|Pseudonocardiales	201174|Actinobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TLS3_k127_4045772_0	1120948.KB903224_gene356	1.246e-189	596.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4DYGS@85010|Pseudonocardiales	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
TLS3_k127_4045772_4	1120948.KB903224_gene357	2.628e-60	211.0	COG3832@1|root,COG3832@2|Bacteria,2IFJT@201174|Actinobacteria,4E4TI@85010|Pseudonocardiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_4045772_2	1120948.KB903224_gene359	4.522e-129	421.0	COG2022@1|root,COG2022@2|Bacteria,2GM62@201174|Actinobacteria,4DY5Y@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0008150,GO:0040007	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
TLS3_k127_4045772_6	28042.GU90_17450	1.106e-14	76.0	COG2104@1|root,COG2104@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiS	-	-	ko:K03154,ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
TLS3_k127_4045772_1	1120948.KB903224_gene361	1.251e-144	471.0	COG0665@1|root,COG0665@2|Bacteria,2GJVR@201174|Actinobacteria,4DZAH@85010|Pseudonocardiales	201174|Actinobacteria	E	TIGRFAM glycine oxidase ThiO	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
TLS3_k127_4045772_3	1120948.KB903224_gene362	8.657e-96	321.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria,4DY75@85010|Pseudonocardiales	201174|Actinobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0414c	TMP-TENI
TLS3_k127_4045772_5	405948.SACE_6506	2.344e-54	201.0	COG3064@1|root,COG3064@2|Bacteria,2I349@201174|Actinobacteria,4EF7A@85010|Pseudonocardiales	201174|Actinobacteria	M	Alpha-lytic protease prodomain	-	-	-	ko:K18546	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Pro_Al_protease,Trypsin,fn3
TLS3_k127_4046032_4	1120948.KB903243_gene2596	4.704e-31	123.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4DZE6@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
TLS3_k127_4046032_3	1120949.KB903295_gene2171	4.205e-34	139.0	COG5637@1|root,COG5637@2|Bacteria,2IN7X@201174|Actinobacteria,4DFFH@85008|Micromonosporales	201174|Actinobacteria	S	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_4046032_0	1343740.M271_34785	3.246e-141	456.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria	201174|Actinobacteria	S	alcohol dehydrogenase	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_4046032_1	1120948.KB903231_gene4714	2.642e-77	263.0	COG1309@1|root,COG1309@2|Bacteria,2H47F@201174|Actinobacteria,4E29X@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_4046032_2	1120948.KB903244_gene2895	1.041e-43	168.0	COG3021@1|root,COG3021@2|Bacteria,2GKXC@201174|Actinobacteria,4DZ69@85010|Pseudonocardiales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_4048209_2	675635.Psed_5489	1.377e-55	198.0	COG3193@1|root,COG3193@2|Bacteria,2IK20@201174|Actinobacteria,4E7NC@85010|Pseudonocardiales	201174|Actinobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
TLS3_k127_4048209_0	1120948.KB903218_gene1878	6.452e-138	462.0	COG2208@1|root,COG2208@2|Bacteria,2GKN8@201174|Actinobacteria,4DZ1T@85010|Pseudonocardiales	201174|Actinobacteria	KT	Serine phosphatase RsbU, regulator of sigma subunit	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
TLS3_k127_4048209_1	1120948.KB903218_gene1879	7.462e-90	326.0	COG5012@1|root,COG5012@2|Bacteria,2GKAY@201174|Actinobacteria,4DXWT@85010|Pseudonocardiales	201174|Actinobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
TLS3_k127_4055716_2	1120948.KB903244_gene3167	1.011e-133	427.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria,4DYGQ@85010|Pseudonocardiales	201174|Actinobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
TLS3_k127_4055716_1	1120948.KB903244_gene3165	1.434e-135	449.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,4DXA9@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Acetyltransferase (GNAT) family	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
TLS3_k127_4055716_3	1120948.KB903244_gene3164	2.885e-29	125.0	2E6D0@1|root,3310N@2|Bacteria,2GQP8@201174|Actinobacteria,4E6Z2@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3054)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3054
TLS3_k127_4055716_0	1120948.KB903244_gene3163	2.978e-167	533.0	COG0024@1|root,COG0024@2|Bacteria,2GKIZ@201174|Actinobacteria,4E03C@85010|Pseudonocardiales	201174|Actinobacteria	E	Methionine aminopeptidase	map	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
TLS3_k127_4058869_4	1120948.KB903240_gene3736	2.265e-66	231.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria,4E0MV@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
TLS3_k127_4058869_0	1120948.KB903226_gene5450	7.419e-248	768.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4DX7K@85010|Pseudonocardiales	201174|Actinobacteria	E	Alanine dehydrogenase/PNT, C-terminal domain	fdhA	-	1.2.1.46	ko:K00148	ko00625,ko00680,ko01100,ko01120,ko01200,map00625,map00680,map01100,map01120,map01200	-	R00604	RC00188	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N,AlaDh_PNT_C
TLS3_k127_4058869_3	1120948.KB903217_gene1038	4.269e-96	349.0	2DBB1@1|root,2Z854@2|Bacteria,2GNBN@201174|Actinobacteria,4E2J6@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
TLS3_k127_4058869_1	1120948.KB903217_gene1039	1.984e-237	755.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,4DZ9B@85010|Pseudonocardiales	201174|Actinobacteria	V	VanW like protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
TLS3_k127_4058869_5	1123023.JIAI01000005_gene645	4.241e-40	154.0	COG0234@1|root,COG0234@2|Bacteria,2IHRC@201174|Actinobacteria,4E4DG@85010|Pseudonocardiales	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groES2	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
TLS3_k127_4058869_2	1120948.KB903217_gene1041	2.529e-234	728.0	COG1672@1|root,COG1672@2|Bacteria,2GWBV@201174|Actinobacteria,4DX9M@85010|Pseudonocardiales	201174|Actinobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
TLS3_k127_4058869_6	1127134.NOCYR_2070	2.988e-20	95.0	COG0786@1|root,COG0786@2|Bacteria,2I9AV@201174|Actinobacteria,4FYWF@85025|Nocardiaceae	201174|Actinobacteria	E	Sodium glutamate symporter	-	-	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	-	Glt_symporter
TLS3_k127_4070127_1	1120948.KB903244_gene2929	2.196e-68	236.0	COG0454@1|root,COG1042@1|root,COG0456@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4DYY0@85010|Pseudonocardiales	201174|Actinobacteria	CK	Acyl-CoA synthetase (NDP forming)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
TLS3_k127_4070127_2	1120948.KB903244_gene2928	3.416e-36	144.0	2F8ES@1|root,340TH@2|Bacteria,2GVJ6@201174|Actinobacteria,4E6KD@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4070127_0	1120948.KB903244_gene2927	5.322e-111	359.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4DY5T@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigB	GO:0000988,GO:0000990,GO:0001666,GO:0002791,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009410,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS3_k127_4098759_0	1120948.KB903245_gene3564	2.336e-308	954.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4E0P6@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
TLS3_k127_4098759_4	2074.JNYD01000017_gene4294	1.388e-62	239.0	2F92T@1|root,341EE@2|Bacteria,2GPMN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4098759_3	1120948.KB903248_gene4300	8.694e-101	349.0	COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,4DZ4C@85010|Pseudonocardiales	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
TLS3_k127_4098759_1	1120948.KB903245_gene3565	3.009e-150	483.0	COG0620@1|root,COG0620@2|Bacteria,2GMPS@201174|Actinobacteria,4DYCR@85010|Pseudonocardiales	201174|Actinobacteria	E	Methionine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
TLS3_k127_4098759_2	1120948.KB903245_gene3567	3.081e-121	403.0	2BYH3@1|root,2Z7SZ@2|Bacteria,2GMTF@201174|Actinobacteria,4DZHX@85010|Pseudonocardiales	201174|Actinobacteria	S	3-methyladenine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4098759_5	1048339.KB913029_gene780	3.068e-06	51.0	28Q5A@1|root,2ZCNA@2|Bacteria,2GVQM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4101935_4	1120948.KB903247_gene4414	2.781e-82	289.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4E158@85010|Pseudonocardiales	201174|Actinobacteria	J	Amidase	amiB	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
TLS3_k127_4101935_3	1120948.KB903247_gene4413	4.061e-104	352.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria,4DXRY@85010|Pseudonocardiales	201174|Actinobacteria	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
TLS3_k127_4101935_1	1120948.KB903247_gene4412	2.184e-144	474.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria,4DXH4@85010|Pseudonocardiales	201174|Actinobacteria	M	Mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
TLS3_k127_4101935_5	1120948.KB903247_gene4411	2.734e-67	232.0	COG2346@1|root,COG2346@2|Bacteria,2IKPF@201174|Actinobacteria,4E3HV@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Bacterial-like globin	glbO	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
TLS3_k127_4101935_2	1120948.KB903247_gene4410	1.453e-124	401.0	COG0412@1|root,COG0412@2|Bacteria,2IG4Y@201174|Actinobacteria,4E2ZB@85010|Pseudonocardiales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
TLS3_k127_4101935_7	1120948.KB903247_gene4409	5.433e-36	150.0	2DQ1M@1|root,32UNB@2|Bacteria,2GJD1@201174|Actinobacteria,4E2JU@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4101935_6	1120948.KB903247_gene4408	4.758e-48	178.0	COG0824@1|root,COG0824@2|Bacteria,2IFAK@201174|Actinobacteria,4E5TH@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
TLS3_k127_4101935_0	103733.JNYO01000002_gene666	0.0	1794.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,4DY95@85010|Pseudonocardiales	201174|Actinobacteria	E	Dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
TLS3_k127_4120506_1	2074.JNYD01000003_gene3393	2.539e-25	118.0	COG0346@1|root,COG0346@2|Bacteria,2GQZ9@201174|Actinobacteria,4E6S1@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS3_k127_4120506_0	1957.JODX01000003_gene4847	7.448e-75	264.0	COG2197@1|root,COG2197@2|Bacteria,2IC7E@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_4120781_9	426716.JOAJ01000003_gene3787	3.93e-49	180.0	COG1309@1|root,COG1309@2|Bacteria,2ICWK@201174|Actinobacteria,4FYCD@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_4120781_2	1120948.KB903229_gene5226	3.368e-181	583.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4DXRB@85010|Pseudonocardiales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
TLS3_k127_4120781_16	1504822.CCNO01000015_gene899	8.278e-09	65.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
TLS3_k127_4120781_10	1120948.KB903244_gene2834	1.872e-45	182.0	COG0558@1|root,COG0558@2|Bacteria,2I5BP@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf,Sulfatase
TLS3_k127_4120781_6	1123024.AUII01000028_gene2520	1.651e-101	337.0	COG2265@1|root,COG2265@2|Bacteria,2I3SH@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
TLS3_k127_4120781_14	1120948.KB903229_gene5224	2.205e-29	119.0	2DETY@1|root,2ZP91@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
TLS3_k127_4120781_8	1120948.KB903229_gene5221	4.723e-89	301.0	COG4976@1|root,COG4976@2|Bacteria,2IGUS@201174|Actinobacteria,4E3AJ@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4120781_1	1120948.KB903229_gene5219	6.13e-196	624.0	COG0493@1|root,COG0493@2|Bacteria,2GJ4A@201174|Actinobacteria,4E1TE@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridine nucleotide-disulphide oxidoreductase	fprA	GO:0000166,GO:0003674,GO:0003824,GO:0004324,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008860,GO:0016491,GO:0016730,GO:0016731,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0055114,GO:0070401,GO:0071944,GO:0097159,GO:1901265,GO:1901363	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_4120781_11	1120948.KB903229_gene5217	2.021e-35	147.0	2AQDJ@1|root,32JWI@2|Bacteria,2HS8D@201174|Actinobacteria,4ECVJ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4120781_12	1120948.KB903229_gene5216	3.337e-35	141.0	COG2072@1|root,COG2072@2|Bacteria,2GR91@201174|Actinobacteria,4E5JK@85010|Pseudonocardiales	201174|Actinobacteria	P	Domain of unknown function (DUF4873)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4873
TLS3_k127_4120781_5	1120948.KB903229_gene5215	1.813e-105	348.0	COG1309@1|root,COG1309@2|Bacteria,2GN0W@201174|Actinobacteria,4E048@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_4120781_4	1120948.KB903229_gene5214	9.854e-153	489.0	COG3396@1|root,COG3396@2|Bacteria,2GMBI@201174|Actinobacteria,4DYYP@85010|Pseudonocardiales	201174|Actinobacteria	S	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
TLS3_k127_4120781_7	1120948.KB903229_gene5213	1.797e-101	355.0	COG2267@1|root,COG2267@2|Bacteria,2IFZ5@201174|Actinobacteria,4E0JD@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
TLS3_k127_4120781_0	1068980.ARVW01000001_gene4818	6.706e-204	646.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria,4E05U@85010|Pseudonocardiales	201174|Actinobacteria	P	flavoprotein involved in K transport	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,Pyr_redox_3
TLS3_k127_4120781_3	1120948.KB903229_gene5211	9.726e-164	518.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,4DX4D@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA thioesterase	-	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
TLS3_k127_4134154_1	1120948.KB903244_gene3118	9.947e-53	190.0	COG1492@1|root,COG1492@2|Bacteria,2GJ1W@201174|Actinobacteria,4DYZN@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA,GATase_3
TLS3_k127_4134154_0	1120948.KB903244_gene3115	1.598e-206	648.0	COG3268@1|root,COG3268@2|Bacteria,2GNGH@201174|Actinobacteria,4E2CJ@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Saccharopine dehydrogenase	LYS1	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0022607,GO:0030312,GO:0042546,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K12445	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	Sacchrp_dh_NADP
TLS3_k127_4142566_0	1120948.KB903247_gene4478	2.006e-199	639.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4DXRM@85010|Pseudonocardiales	201174|Actinobacteria	J	ribonuclease, Rne Rng family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
TLS3_k127_4145872_1	1120948.KB903240_gene4061	4.421e-121	412.0	COG1247@1|root,COG1247@2|Bacteria,2I49I@201174|Actinobacteria,4E02X@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
TLS3_k127_4145872_0	1123023.JIAI01000020_gene2154	9.861e-131	428.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria,4DX8P@85010|Pseudonocardiales	201174|Actinobacteria	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
TLS3_k127_4145872_2	1120948.KB903240_gene4059	1.724e-83	299.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4DYWG@85010|Pseudonocardiales	201174|Actinobacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
TLS3_k127_4162208_2	1120948.KB903231_gene4744	6.269e-58	207.0	COG3824@1|root,COG3824@2|Bacteria,2IS6W@201174|Actinobacteria,4E3AC@85010|Pseudonocardiales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
TLS3_k127_4162208_3	1179773.BN6_76200	4.412e-43	171.0	2C7XW@1|root,32RR4@2|Bacteria,2IQ5R@201174|Actinobacteria,4E4AT@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3499
TLS3_k127_4162208_0	1120948.KB903231_gene4742	5.629e-231	722.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4DXQW@85010|Pseudonocardiales	201174|Actinobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	manB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TLS3_k127_4162208_4	1120948.KB903231_gene4741	3.594e-24	108.0	COG2835@1|root,COG2835@2|Bacteria,2HUT5@201174|Actinobacteria,4E6TY@85010|Pseudonocardiales	201174|Actinobacteria	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
TLS3_k127_4162208_1	1120948.KB903231_gene4740	2.181e-88	299.0	COG1737@1|root,COG1737@2|Bacteria,2GMG0@201174|Actinobacteria,4DXU4@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	bact-PGI_C
TLS3_k127_4187208_0	1120948.KB903238_gene165	2.477e-36	137.0	COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,4DXYM@85010|Pseudonocardiales	201174|Actinobacteria	S	ABC transporter	yjjK	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
TLS3_k127_4195676_0	1120948.KB903229_gene5396	1.128e-129	419.0	COG0846@1|root,COG0846@2|Bacteria,2IAS0@201174|Actinobacteria,4DYXE@85010|Pseudonocardiales	201174|Actinobacteria	K	NAD-dependent protein deacetylase, SIR2 family	-	-	-	-	-	-	-	-	-	-	-	-	SIR2
TLS3_k127_4195676_1	1089545.KB913037_gene5590	2.837e-63	226.0	COG3416@1|root,COG3416@2|Bacteria,2HVVA@201174|Actinobacteria,4E318@85010|Pseudonocardiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
TLS3_k127_4196137_4	1120948.KB903229_gene5180	3.296e-34	133.0	COG3963@1|root,COG3963@2|Bacteria,2I93P@201174|Actinobacteria,4E3Y8@85010|Pseudonocardiales	201174|Actinobacteria	I	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,RrnaAD
TLS3_k127_4196137_3	1120948.KB903229_gene5182	2.418e-49	181.0	COG0266@1|root,COG0266@2|Bacteria,2IM40@201174|Actinobacteria,4E5KR@85010|Pseudonocardiales	201174|Actinobacteria	L	class I DNA-(apurinic or apyrimidinic site) endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4196137_2	1120948.KB903229_gene5184	1.114e-85	310.0	COG3576@1|root,COG3576@2|Bacteria,2GP9M@201174|Actinobacteria,4E330@85010|Pseudonocardiales	201174|Actinobacteria	C	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
TLS3_k127_4196137_1	1120948.KB903229_gene5185	8.635e-116	398.0	COG0491@1|root,COG0491@2|Bacteria,2GMDD@201174|Actinobacteria,4DX45@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_4196137_0	65497.JODV01000017_gene2982	2.663e-179	587.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4DYSY@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2,Viral_helicase1
TLS3_k127_4199502_12	2074.JNYD01000007_gene2085	1.171e-06	54.0	COG2258@1|root,COG2258@2|Bacteria,2IH5Z@201174|Actinobacteria,4E3XC@85010|Pseudonocardiales	201174|Actinobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4199502_0	1120948.KB903217_gene863	9.169e-113	376.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4E0PH@85010|Pseudonocardiales	201174|Actinobacteria	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_4199502_2	313589.JNB_13688	3.156e-96	331.0	COG1215@1|root,COG1215@2|Bacteria,2HEX7@201174|Actinobacteria,4FI6G@85021|Intrasporangiaceae	201174|Actinobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4199502_5	452863.Achl_3411	8.768e-68	240.0	COG0726@1|root,COG0726@2|Bacteria,2HEQK@201174|Actinobacteria	201174|Actinobacteria	G	polysaccharide deacetylase	xynD	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	CBM_2,Polysacc_deac_1
TLS3_k127_4199502_10	1157632.AQWQ01000010_gene583	7.453e-14	85.0	COG0515@1|root,COG4403@1|root,COG0515@2|Bacteria,COG4403@2|Bacteria,2GMRN@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like,Pkinase
TLS3_k127_4199502_7	1120948.KB903217_gene842	7.361e-58	214.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	FHA,HTH_8,Sigma54_activat,Yop-YscD_cpl
TLS3_k127_4199502_4	2074.JNYD01000004_gene4896	3.533e-88	295.0	COG0644@1|root,COG0644@2|Bacteria,2HRCE@201174|Actinobacteria,4EAHQ@85010|Pseudonocardiales	201174|Actinobacteria	C	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
TLS3_k127_4199502_8	1120948.KB903217_gene840	1.118e-43	166.0	COG1846@1|root,COG1846@2|Bacteria,2IB1S@201174|Actinobacteria,4E63B@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
TLS3_k127_4199502_6	709986.Deima_0891	2.512e-63	224.0	COG0346@1|root,COG0346@2|Bacteria,1WMMN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
TLS3_k127_4199502_3	1120948.KB903220_gene132	3.589e-91	308.0	COG3707@1|root,COG3707@2|Bacteria,2I2Q0@201174|Actinobacteria,4E63F@85010|Pseudonocardiales	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
TLS3_k127_4199502_9	1120948.KB903218_gene2072	6.816e-16	78.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4E32T@85010|Pseudonocardiales	201174|Actinobacteria	L	HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH
TLS3_k127_4219842_0	1120948.KB903217_gene1034	3.678e-179	572.0	COG0277@1|root,COG0277@2|Bacteria,2H3QX@201174|Actinobacteria,4EA7Y@85010|Pseudonocardiales	201174|Actinobacteria	C	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
TLS3_k127_4219842_1	1120948.KB903217_gene1035	1.146e-27	130.0	COG1289@1|root,COG1289@2|Bacteria,2GMS1@201174|Actinobacteria,4E1U9@85010|Pseudonocardiales	201174|Actinobacteria	M	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC,FUSC_2
TLS3_k127_4222302_0	1120948.KB903221_gene429	5.334e-133	439.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE,Trans_reg_C
TLS3_k127_4223724_0	1120948.KB903229_gene5231	1.954e-145	468.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DYWA@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_4223724_1	1120948.KB903229_gene5232	9.326e-127	427.0	COG0842@1|root,COG0842@2|Bacteria,2GP9E@201174|Actinobacteria,4E0GK@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
TLS3_k127_4223724_4	58123.JOFJ01000003_gene2132	6.055e-06	58.0	2DRBI@1|root,33B4D@2|Bacteria,2I13H@201174|Actinobacteria,4EKM4@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4223724_2	1120948.KB903245_gene3516	3.382e-43	166.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	dddL	-	1.13.11.6,4.4.1.3	ko:K00452,ko:K11312,ko:K16953	ko00380,ko00920,ko01100,map00380,map00920,map01100	M00038	R02574,R02665	RC00387,RC00747,RC00748	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,DMSP_lyase
TLS3_k127_4223724_3	1120948.KB903240_gene3947	1.664e-16	80.0	COG2154@1|root,COG2154@2|Bacteria,2GW4N@201174|Actinobacteria,4E718@85010|Pseudonocardiales	201174|Actinobacteria	H	Uncharacterized conserved protein (DUF2267)	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	DUF2267,Pterin_4a
TLS3_k127_4229645_5	448385.sce6417	1.823e-43	162.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,437V1@68525|delta/epsilon subdivisions,2X34I@28221|Deltaproteobacteria,2YU7X@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_4229645_1	1120948.KB903240_gene3985	1e-125	410.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4DZTD@85010|Pseudonocardiales	201174|Actinobacteria	E	imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16,5.3.1.24	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	M00023,M00026	R03509,R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
TLS3_k127_4229645_0	1120948.KB903240_gene3984	1.978e-145	464.0	COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria,4DZBH@85010|Pseudonocardiales	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007	4.1.3.27	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023,M00026	R00985,R00986,R04558	RC00010,RC01190,RC01943,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
TLS3_k127_4229645_4	994479.GL877878_gene650	1.519e-47	185.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4E4DQ@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	GO:0008150,GO:0040007	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1606	PRA-CH
TLS3_k127_4229645_8	797515.HMPREF9103_00686	1.536e-16	87.0	COG0454@1|root,COG0456@2|Bacteria,1V562@1239|Firmicutes,4HMAE@91061|Bacilli,3F9ST@33958|Lactobacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
TLS3_k127_4229645_7	479432.Sros_5540	5.598e-30	135.0	COG0477@1|root,COG2814@2|Bacteria,2I2ID@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
TLS3_k127_4229645_3	1463936.JOJI01000058_gene6134	1.405e-71	272.0	COG3899@1|root,COG3903@1|root,COG3899@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
TLS3_k127_4229645_6	483219.LILAB_21960	1.107e-39	160.0	COG1247@1|root,COG1247@2|Bacteria,1R9WS@1224|Proteobacteria,42RZM@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_4229645_2	1120948.KB903240_gene3982	2.703e-120	394.0	COG0583@1|root,COG0583@2|Bacteria,2GM99@201174|Actinobacteria,4E13Q@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS3_k127_4241_1	1120948.KB903229_gene5397	1.006e-43	167.0	COG2329@1|root,COG2329@2|Bacteria,2IM1Q@201174|Actinobacteria,4E4RW@85010|Pseudonocardiales	201174|Actinobacteria	S	enzyme involved in biosynthesis of extracellular polysaccharides	-	-	1.14.99.57	ko:K21481	-	-	-	-	ko00000,ko01000	-	-	-	ABM
TLS3_k127_4241_0	1120948.KB903229_gene5398	6.936e-145	466.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,4DXH2@85010|Pseudonocardiales	201174|Actinobacteria	L	A G-specific DNA glycosylase	mutY	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
TLS3_k127_4241_2	1120948.KB903229_gene5399	3.166e-26	117.0	COG1572@1|root,COG1572@2|Bacteria,2I2R9@201174|Actinobacteria,4E4VU@85010|Pseudonocardiales	201174|Actinobacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	DUF4232
TLS3_k127_4248788_0	1120948.KB903218_gene1879	2.198e-120	393.0	COG5012@1|root,COG5012@2|Bacteria,2GKAY@201174|Actinobacteria,4DXWT@85010|Pseudonocardiales	201174|Actinobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
TLS3_k127_4248788_2	1120948.KB903218_gene1880	8.321e-20	102.0	COG1366@1|root,COG1366@2|Bacteria,2HNP8@201174|Actinobacteria,4E80D@85010|Pseudonocardiales	201174|Actinobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS_2
TLS3_k127_4248788_1	1120948.KB903218_gene1884	1.111e-80	271.0	COG0596@1|root,COG0596@2|Bacteria,2H4IZ@201174|Actinobacteria,4DYNZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
TLS3_k127_4265218_0	2074.JNYD01000019_gene2465	4.221e-139	452.0	COG0318@1|root,COG0318@2|Bacteria,2IA5S@201174|Actinobacteria,4E8RA@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_4265218_1	2074.JNYD01000019_gene2440	1.138e-61	233.0	COG1309@1|root,COG1309@2|Bacteria,2GKE2@201174|Actinobacteria,4E2WY@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
TLS3_k127_4268467_0	1123023.JIAI01000014_gene3646	6.458e-118	387.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4DZQT@85010|Pseudonocardiales	201174|Actinobacteria	L	ATP-dependent DNA helicase	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
TLS3_k127_4268467_1	1120948.KB903217_gene1643	2.421e-88	300.0	COG0739@1|root,COG0739@2|Bacteria,2GM7Q@201174|Actinobacteria,4EEDG@85010|Pseudonocardiales	201174|Actinobacteria	M	Peptidase family M23	mepA	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
TLS3_k127_4283569_0	1120948.KB903247_gene4476	0.0	1116.0	COG1032@1|root,COG1032@2|Bacteria,2GJY1@201174|Actinobacteria,4DXFP@85010|Pseudonocardiales	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TLS3_k127_4283569_1	675635.Psed_1985	3.059e-32	146.0	COG1247@1|root,COG1247@2|Bacteria,2IM56@201174|Actinobacteria,4E62E@85010|Pseudonocardiales	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
TLS3_k127_4293555_2	1120948.KB903218_gene1861	5.013e-24	113.0	COG2124@1|root,COG2124@2|Bacteria,2GNJI@201174|Actinobacteria,4DXRC@85010|Pseudonocardiales	201174|Actinobacteria	Q	cytochrome P450	eryK	GO:0000166,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0019748,GO:0020037,GO:0030638,GO:0030639,GO:0033067,GO:0033068,GO:0036094,GO:0044237,GO:0044249,GO:0044550,GO:0046483,GO:0046906,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901363,GO:1901576	1.14.13.154	ko:K14370	ko00522,ko01052,ko01130,map00522,map01052,map01130	M00774	R05521,R05522	RC01892	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	-	-	-	p450
TLS3_k127_4293555_1	345341.KUTG_07840	2.86e-51	190.0	COG1309@1|root,COG1309@2|Bacteria,2IMCP@201174|Actinobacteria,4E5M1@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_4293555_0	1120948.KB903218_gene1859	2.488e-152	490.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria,4E2YU@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
TLS3_k127_4298627_1	1120948.KB903247_gene4479	2.178e-46	169.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4E4K1@85010|Pseudonocardiales	201174|Actinobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
TLS3_k127_4298627_2	1120948.KB903247_gene4480	6.072e-44	161.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4E5NQ@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
TLS3_k127_4298627_0	1120948.KB903247_gene4481	1.078e-232	736.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4DXZ0@85010|Pseudonocardiales	201174|Actinobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
TLS3_k127_4299020_0	1120948.KB903217_gene1362	2.229e-187	605.0	COG1680@1|root,COG1680@2|Bacteria,2H2SY@201174|Actinobacteria,4DXGA@85010|Pseudonocardiales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_4299020_1	287986.DV20_39150	2.41e-134	433.0	COG0596@1|root,COG0596@2|Bacteria,2GJCT@201174|Actinobacteria,4DZI3@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	3.8.1.3	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
TLS3_k127_4299020_3	1120948.KB903217_gene1361	6.595e-83	290.0	COG0654@1|root,COG0654@2|Bacteria,2GIZU@201174|Actinobacteria,4DXIV@85010|Pseudonocardiales	201174|Actinobacteria	CH	FAD binding domain	-	-	1.14.13.218,1.14.13.24	ko:K20940,ko:K22270	ko00362,ko00405,ko01120,ko01130,map00362,map00405,map01120,map01130	M00835	R02589	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
TLS3_k127_4299020_4	675635.Psed_2018	3.919e-25	120.0	COG0671@1|root,COG0671@2|Bacteria,2I9FB@201174|Actinobacteria,4E7YS@85010|Pseudonocardiales	201174|Actinobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
TLS3_k127_4299020_2	1120948.KB903217_gene1359	4.365e-100	345.0	COG0697@1|root,COG0697@2|Bacteria,2H9P8@201174|Actinobacteria,4EBMC@85010|Pseudonocardiales	201174|Actinobacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4299884_1	405948.SACE_5736	8.303e-108	365.0	COG1807@1|root,COG1807@2|Bacteria,2GKH9@201174|Actinobacteria,4DXMQ@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Mycobacterial cell wall arabinan synthesis protein	-	-	-	ko:K11385,ko:K11386,ko:K11387	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Arabino_trans_C,Arabinose_trans
TLS3_k127_4299884_0	1120948.KB903219_gene746	1.104e-212	672.0	COG1807@1|root,COG1807@2|Bacteria,2GKH9@201174|Actinobacteria,4DYSK@85010|Pseudonocardiales	201174|Actinobacteria	M	Mycobacterial cell wall arabinan synthesis protein	-	-	-	ko:K11386	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Arabino_trans_C,Arabinose_trans
TLS3_k127_4322386_5	1120948.KB903217_gene1390	2.857e-41	153.0	COG5470@1|root,COG5470@2|Bacteria,2IKVB@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
TLS3_k127_4322386_3	526225.Gobs_4536	1.877e-53	191.0	COG0789@1|root,COG0789@2|Bacteria,2INKP@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind
TLS3_k127_4322386_2	1120948.KB903217_gene1367	1.576e-65	228.0	2C75R@1|root,2ZCK5@2|Bacteria,2IBVD@201174|Actinobacteria,4E8JR@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4322386_0	1120948.KB903217_gene1368	6.51e-136	436.0	COG1028@1|root,COG1028@2|Bacteria,2I8GX@201174|Actinobacteria,4DX51@85010|Pseudonocardiales	201174|Actinobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
TLS3_k127_4322386_4	215803.DB30_4561	7.317e-42	175.0	COG0451@1|root,COG0451@2|Bacteria,1RBSM@1224|Proteobacteria,42XUG@68525|delta/epsilon subdivisions,2WTSY@28221|Deltaproteobacteria,2YX8Q@29|Myxococcales	28221|Deltaproteobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	1.3.1.45	ko:K05281	ko00943,ko01110,map00943,map01110	-	R06562,R06563,R07747,R07751	RC00805	ko00000,ko00001,ko01000	-	-	-	Epimerase
TLS3_k127_4322386_1	1160718.SU9_26119	1.561e-76	266.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria	201174|Actinobacteria	J	Phenazine biosynthesis protein PhzF	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
TLS3_k127_4339057_0	1120948.KB903240_gene3986	3.03e-164	544.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DXRK@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_4339057_2	1120948.KB903240_gene3987	8.788e-56	199.0	COG3795@1|root,COG3795@2|Bacteria,2IHYC@201174|Actinobacteria,4E5IG@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
TLS3_k127_4339057_3	1120948.KB903240_gene3988	7.156e-49	190.0	COG3795@1|root,COG3795@2|Bacteria,2IHYC@201174|Actinobacteria,4E3IE@85010|Pseudonocardiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
TLS3_k127_4339057_1	1120948.KB903240_gene3989	1.653e-104	357.0	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4E01N@85010|Pseudonocardiales	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
TLS3_k127_4339057_4	1120948.KB903240_gene3990	1.564e-41	163.0	COG4976@1|root,COG4976@2|Bacteria	2|Bacteria	O	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
TLS3_k127_4360359_1	1120948.KB903240_gene3772	7.449e-138	448.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4DX5D@85010|Pseudonocardiales	201174|Actinobacteria	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TLS3_k127_4360359_0	1120948.KB903240_gene3773	7.77e-165	519.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4DXKZ@85010|Pseudonocardiales	201174|Actinobacteria	O	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
TLS3_k127_4368913_2	1120948.KB903244_gene3138	1.34e-42	163.0	COG1018@1|root,COG3239@1|root,COG1018@2|Bacteria,COG3239@2|Bacteria,2GKGS@201174|Actinobacteria,4E9EK@85010|Pseudonocardiales	201174|Actinobacteria	C	Fatty acid desaturase	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,FA_desaturase,Fer2,NAD_binding_1
TLS3_k127_4368913_1	1463900.JOIX01000019_gene63	6.625e-73	256.0	COG2207@1|root,COG2207@2|Bacteria,2GK7C@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_4368913_3	1120948.KB903243_gene2507	5.208e-40	164.0	COG2764@1|root,COG2764@2|Bacteria,2IFK2@201174|Actinobacteria,4E5GK@85010|Pseudonocardiales	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_4368913_0	68199.JNZO01000008_gene7696	1.126e-113	381.0	COG0654@1|root,COG0654@2|Bacteria,2I2TH@201174|Actinobacteria	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
TLS3_k127_4395162_4	1120948.KB903224_gene313	4.267e-173	558.0	COG0543@1|root,COG1017@1|root,COG0543@2|Bacteria,COG1017@2|Bacteria,2GKXT@201174|Actinobacteria,4DXMR@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the globin family	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Globin,NAD_binding_1
TLS3_k127_4395162_3	1120948.KB903224_gene311	3.06e-211	667.0	COG4362@1|root,COG4362@2|Bacteria,2GZ16@201174|Actinobacteria,4E0P8@85010|Pseudonocardiales	201174|Actinobacteria	EP	Belongs to the NOS family. Bacterial NOS oxygenase subfamily	nos	-	1.14.14.47	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	-	R11711,R11712,R11713	RC00177,RC00330,RC01044	ko00000,ko00001,ko01000	-	-	-	NO_synthase
TLS3_k127_4395162_5	1120948.KB903224_gene310	4.589e-123	402.0	COG0500@1|root,COG2226@2|Bacteria,2GMZW@201174|Actinobacteria,4E5AC@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
TLS3_k127_4395162_0	1120948.KB903224_gene309	4.846e-306	941.0	COG3552@1|root,COG3552@2|Bacteria,2I020@201174|Actinobacteria,4DZJE@85010|Pseudonocardiales	201174|Actinobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
TLS3_k127_4395162_2	1120948.KB903224_gene308	9.554e-215	674.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4E1M8@85010|Pseudonocardiales	201174|Actinobacteria	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
TLS3_k127_4395162_1	1120948.KB903224_gene307	7.552e-279	857.0	COG1454@1|root,COG1454@2|Bacteria,2GNHQ@201174|Actinobacteria,4DZ4Z@85010|Pseudonocardiales	201174|Actinobacteria	C	Iron-containing alcohol dehydrogenase	-	-	1.1.99.37,1.2.98.1	ko:K17067	ko00625,ko00680,ko01120,ko01200,map00625,map00680,map01120,map01200	-	R00614	RC00034,RC00188	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
TLS3_k127_4402960_6	1120948.KB903223_gene183	3.681e-46	174.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4DZBG@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TLS3_k127_4402960_2	1120948.KB903218_gene2246	6.909e-100	341.0	COG0739@1|root,COG0739@2|Bacteria,2GKXN@201174|Actinobacteria,4E2QB@85010|Pseudonocardiales	201174|Actinobacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4402960_8	2074.JNYD01000027_gene7366	1.185e-34	151.0	COG1846@1|root,COG1846@2|Bacteria,2IHQU@201174|Actinobacteria,4E51R@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
TLS3_k127_4402960_4	1120948.KB903218_gene2247	2.126e-57	218.0	COG1030@1|root,COG1030@2|Bacteria,2IIZ2@201174|Actinobacteria,4E595@85010|Pseudonocardiales	201174|Actinobacteria	-	-	wcoO	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
TLS3_k127_4402960_9	1120948.KB903218_gene2249	1.858e-06	51.0	COG0657@1|root,COG0657@2|Bacteria,2GTEV@201174|Actinobacteria,4E4UB@85010|Pseudonocardiales	201174|Actinobacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
TLS3_k127_4402960_3	1380393.JHVP01000008_gene4658	4.058e-74	258.0	COG0491@1|root,COG0491@2|Bacteria,2H8JM@201174|Actinobacteria,4EWUJ@85013|Frankiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_4402960_5	67281.JNZZ01000028_gene3053	1.835e-49	181.0	COG1914@1|root,COG1914@2|Bacteria,2IBKH@201174|Actinobacteria,418F3@629295|Streptomyces griseus group	201174|Actinobacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
TLS3_k127_4402960_1	1463854.JOHT01000030_gene6919	2.794e-113	394.0	COG1914@1|root,COG1914@2|Bacteria,2IBKH@201174|Actinobacteria	201174|Actinobacteria	P	Mn2 and Fe2 transporters of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
TLS3_k127_4402960_0	2074.JNYD01000014_gene7030	7.786e-135	435.0	COG0604@1|root,COG0604@2|Bacteria,2GRJM@201174|Actinobacteria,4DZWE@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
TLS3_k127_4402960_7	67257.JODR01000014_gene5693	3.945e-38	154.0	COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
TLS3_k127_4408262_0	1157638.KB892162_gene2358	0.0	1062.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
TLS3_k127_4408262_1	1179773.BN6_26920	2.8e-117	394.0	COG0477@1|root,COG2814@2|Bacteria,2I2IS@201174|Actinobacteria,4EE8E@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
TLS3_k127_4408262_7	1448389.BAVQ01000043_gene1737	1.025e-06	55.0	COG3237@1|root,COG3237@2|Bacteria	2|Bacteria	K	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
TLS3_k127_4408262_3	471852.Tcur_2353	1.018e-45	169.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_4408262_2	1179773.BN6_26900	2.312e-79	278.0	COG2375@1|root,COG2375@2|Bacteria,2GK5X@201174|Actinobacteria,4DZNX@85010|Pseudonocardiales	201174|Actinobacteria	P	Siderophore-interacting protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_9,SIP
TLS3_k127_4408262_5	1449069.JMLO01000008_gene3556	3.414e-28	120.0	COG3251@1|root,COG3251@2|Bacteria,2GQFU@201174|Actinobacteria,4G2YD@85025|Nocardiaceae	201174|Actinobacteria	S	MbtH-like protein	-	-	-	ko:K05375	ko00261,ko01130,map00261,map01130	M00736	R10880	RC00064,RC00141,RC03296,RC03297,RC03298	ko00000,ko00001,ko00002	-	-	-	MbtH
TLS3_k127_4408262_6	502025.Hoch_2020	8.783e-21	95.0	COG1535@1|root,COG3433@1|root,COG1535@2|Bacteria,COG3433@2|Bacteria,1MW2U@1224|Proteobacteria,437X4@68525|delta/epsilon subdivisions,2X9QG@28221|Deltaproteobacteria,2YUKW@29|Myxococcales	28221|Deltaproteobacteria	Q	Isochorismatase family	mxcF	-	3.3.2.1,6.3.2.14	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R03037,R07644	RC00162,RC00350,RC02148,RC03046	ko00000,ko00001,ko01000,ko01008	-	-	-	Isochorismatase,PP-binding
TLS3_k127_4408262_4	469383.Cwoe_2691	5.097e-44	162.0	COG1120@1|root,COG1120@2|Bacteria,2GJ49@201174|Actinobacteria,4CP89@84995|Rubrobacteria	84995|Rubrobacteria	HP	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
TLS3_k127_4409574_4	1120948.KB903245_gene3614	1.897e-150	490.0	COG2321@1|root,COG2321@2|Bacteria,2HBKZ@201174|Actinobacteria,4E0JE@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zn_peptidase
TLS3_k127_4409574_1	1828.JOKB01000012_gene5404	0.0	1022.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4FTY8@85025|Nocardiaceae	201174|Actinobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
TLS3_k127_4409574_3	1120948.KB903245_gene3612	3.989e-187	621.0	COG3281@1|root,COG3281@2|Bacteria,2GKAP@201174|Actinobacteria,4E0QY@85010|Pseudonocardiales	201174|Actinobacteria	G	protein, probably involved in trehalose biosynthesis	mak	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576	2.7.1.175	ko:K16146	ko00500,ko01100,map00500,map01100	-	R09945	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
TLS3_k127_4409574_0	1120948.KB903245_gene3611	0.0	1139.0	COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,4DXQ2@85010|Pseudonocardiales	201174|Actinobacteria	G	Alpha amylase, catalytic domain	treS	GO:0000023,GO:0000271,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016160,GO:0016161,GO:0016787,GO:0016798,GO:0016853,GO:0016866,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0047471,GO:0055114,GO:0071704,GO:0071944,GO:1901576	3.2.1.1,3.2.1.20,5.4.99.16	ko:K01187,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01557,R02108,R02112,R06087,R06088,R11262	RC00028,RC00049,RC00077,RC01816	ko00000,ko00001,ko01000	-	GH13,GH31	iNJ661.Rv0126	Alpha-amylase,Malt_amylase_C
TLS3_k127_4409574_6	1120948.KB903245_gene3610	2.658e-43	163.0	COG3030@1|root,COG3030@2|Bacteria,2IA8V@201174|Actinobacteria,4E4VS@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein affecting phage T7 exclusion by the F plasmid	-	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
TLS3_k127_4409574_7	105420.BBPO01000034_gene902	3.509e-20	105.0	COG1846@1|root,COG1846@2|Bacteria,2GUZX@201174|Actinobacteria,2NIWN@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
TLS3_k127_4409574_5	1121946.AUAX01000007_gene2854	1.315e-83	289.0	COG4638@1|root,COG4638@2|Bacteria,2GKMV@201174|Actinobacteria,4D9AM@85008|Micromonosporales	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	-	ko:K19982	ko00404,ko01130,map00404,map01130	M00790	R11107	RC01333	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
TLS3_k127_4409574_2	1033730.CAHG01000010_gene2510	2.145e-300	947.0	COG0366@1|root,COG0366@2|Bacteria,2GJKR@201174|Actinobacteria,4DMZD@85009|Propionibacteriales	201174|Actinobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
TLS3_k127_441050_5	1120948.KB903218_gene2259	1.179e-13	71.0	COG0477@1|root,COG2814@2|Bacteria,2GK8C@201174|Actinobacteria,4DZMT@85010|Pseudonocardiales	201174|Actinobacteria	EGP	arabinose efflux permease	-	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1
TLS3_k127_441050_3	2074.JNYD01000005_gene3174	2.888e-105	350.0	COG0679@1|root,COG0679@2|Bacteria,2GNIA@201174|Actinobacteria,4E3VW@85010|Pseudonocardiales	201174|Actinobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
TLS3_k127_441050_1	1120948.KB903218_gene2264	6.065e-124	406.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4DYZY@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
TLS3_k127_441050_4	263358.VAB18032_23500	7.091e-37	147.0	COG0177@1|root,COG0177@2|Bacteria,2IDQ2@201174|Actinobacteria,4D9JW@85008|Micromonosporales	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_441050_2	2074.JNYD01000003_gene3415	7.084e-118	385.0	COG0614@1|root,COG0614@2|Bacteria,2GYJE@201174|Actinobacteria,4DZ75@85010|Pseudonocardiales	201174|Actinobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
TLS3_k127_441050_0	1120948.KB903218_gene2267	5.406e-134	439.0	COG1020@1|root,COG1020@2|Bacteria,2IGNH@201174|Actinobacteria,4EC1T@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
TLS3_k127_4426051_2	211114.JOEF01000007_gene862	3.315e-12	79.0	COG1302@1|root,COG1302@2|Bacteria,2GS9V@201174|Actinobacteria,4E6FC@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4426051_1	1120948.KB903244_gene2799	1.175e-69	240.0	COG1302@1|root,COG1302@2|Bacteria,2IMA3@201174|Actinobacteria,4E4MA@85010|Pseudonocardiales	201174|Actinobacteria	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
TLS3_k127_4426051_0	1120948.KB903244_gene2798	3.82e-73	256.0	COG1985@1|root,COG1985@2|Bacteria,2GN2P@201174|Actinobacteria,4E0B0@85010|Pseudonocardiales	201174|Actinobacteria	H	Pyrimidine reductase, riboflavin biosynthesis	-	-	1.1.1.193	ko:K00082	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R03458	RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
TLS3_k127_4426051_3	1120948.KB903244_gene2797	4.511e-11	64.0	2E301@1|root,32Y0K@2|Bacteria,2GQTM@201174|Actinobacteria,4E6G2@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3072)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3072
TLS3_k127_4426419_1	1120948.KB903223_gene268	3.732e-127	412.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4E14W@85010|Pseudonocardiales	201174|Actinobacteria	S	overlaps another CDS with the same product name	tlyC	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
TLS3_k127_4426419_0	1120948.KB903223_gene267	9.606e-174	553.0	COG1253@1|root,COG1253@2|Bacteria,2GJ8X@201174|Actinobacteria,4DZW2@85010|Pseudonocardiales	201174|Actinobacteria	S	overlaps another CDS with the same product name	ytfL	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
TLS3_k127_4426419_2	1123024.AUII01000009_gene1986	1.395e-98	349.0	COG3380@1|root,COG3380@2|Bacteria,2IA89@201174|Actinobacteria,4DY1S@85010|Pseudonocardiales	201174|Actinobacteria	S	Flavin containing amine oxidoreductase	-	-	-	ko:K06955	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
TLS3_k127_4436739_2	2074.JNYD01000015_gene4440	5.625e-134	433.0	COG1846@1|root,COG1846@2|Bacteria,2IJJ9@201174|Actinobacteria,4EBKI@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4436739_3	1120948.KB903226_gene5482	1.434e-22	107.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4E1SB@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_4436739_0	675635.Psed_1491	2.662e-221	700.0	COG0365@1|root,COG0365@2|Bacteria,2GJVK@201174|Actinobacteria,4E0VD@85010|Pseudonocardiales	201174|Actinobacteria	I	AMP-binding enzyme C-terminal domain	badA	-	6.2.1.25,6.2.1.50	ko:K04110,ko:K12424	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422,R11608,R11872,R11873	RC00004,RC00174	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_4436739_1	1120948.KB903218_gene1854	1.663e-196	614.0	COG3396@1|root,COG3396@2|Bacteria,2GK2T@201174|Actinobacteria,4DXFS@85010|Pseudonocardiales	201174|Actinobacteria	S	Phenylacetate-CoA oxygenase	boxB	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
TLS3_k127_443688_15	105420.BBPO01000012_gene2077	1.348e-06	61.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,2NI1Q@228398|Streptacidiphilus	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_443688_0	1120948.KB903243_gene2400	0.0	1198.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4E2BB@85010|Pseudonocardiales	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	cutL	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
TLS3_k127_443688_6	1120948.KB903245_gene3473	1.439e-106	353.0	COG3777@1|root,COG3777@2|Bacteria,2HF9K@201174|Actinobacteria,4E3AM@85010|Pseudonocardiales	201174|Actinobacteria	S	3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity	-	-	4.2.1.153	ko:K09709	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00376	R09282	RC02479	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
TLS3_k127_443688_7	1120948.KB903217_gene936	6.791e-80	282.0	COG1846@1|root,COG1846@2|Bacteria,2IJJ9@201174|Actinobacteria,4EBKI@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_443688_1	1120948.KB903247_gene4461	0.0	1073.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4DXIH@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
TLS3_k127_443688_14	1273125.Rrhod_0615	1.059e-11	70.0	COG1983@1|root,COG1983@2|Bacteria,2GQG0@201174|Actinobacteria,4G3X8@85025|Nocardiaceae	201174|Actinobacteria	KT	PspC domain	pspC1	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
TLS3_k127_443688_11	1206731.BAGB01000041_gene8963	2.287e-23	109.0	COG1309@1|root,COG1309@2|Bacteria,2IA5P@201174|Actinobacteria,4G0R1@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_443688_10	1206737.BAGF01000035_gene1940	3.497e-33	140.0	COG1028@1|root,COG1028@2|Bacteria,2GM7N@201174|Actinobacteria,4FZJP@85025|Nocardiaceae	201174|Actinobacteria	IQ	short chain dehydrogenase	-	-	1.3.1.33	ko:K00218	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03845,R06286	RC01008	ko00000,ko00001,ko01000	-	-	-	adh_short
TLS3_k127_443688_12	1120948.KB903218_gene1834	2.412e-21	96.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4DZRP@85010|Pseudonocardiales	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
TLS3_k127_443688_8	65497.JODV01000014_gene3242	5.59e-66	244.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4E2P2@85010|Pseudonocardiales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TLS3_k127_443688_3	1120948.KB903217_gene845	2.135e-189	598.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria,4E0Y5@85010|Pseudonocardiales	201174|Actinobacteria	I	Fatty acid desaturase	desA3	GO:0001676,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016053,GO:0016213,GO:0016215,GO:0016491,GO:0016705,GO:0016717,GO:0019752,GO:0032787,GO:0042759,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:0072330,GO:1901576	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_443688_5	28444.JODQ01000004_gene6186	3.714e-124	417.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4EG8V@85012|Streptosporangiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_443688_13	1283299.AUKG01000002_gene3925	5.877e-15	83.0	COG3685@1|root,COG3685@2|Bacteria,2II1C@201174|Actinobacteria,4CSVV@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
TLS3_k127_443688_9	675635.Psed_3298	3.283e-35	135.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4DZUH@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdnG	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
TLS3_k127_443688_2	675635.Psed_3298	0.0	1011.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4DZUH@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdnG	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
TLS3_k127_443688_4	675635.Psed_3297	1.645e-180	572.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,2GMMC@201174|Actinobacteria,4E076@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.17.1.9,1.6.5.3	ko:K00122,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
TLS3_k127_4441918_12	1120948.KB903217_gene1417	1.145e-24	111.0	COG0695@1|root,COG0695@2|Bacteria,2IR0P@201174|Actinobacteria,4E5DS@85010|Pseudonocardiales	201174|Actinobacteria	O	PFAM Glutaredoxin-like domain (DUF836)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF836
TLS3_k127_4441918_9	1120948.KB903217_gene1418	8.3e-53	196.0	COG1633@1|root,COG1633@2|Bacteria,2I9BU@201174|Actinobacteria	201174|Actinobacteria	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2
TLS3_k127_4441918_10	1120948.KB903217_gene1419	7.324e-35	147.0	2EF56@1|root,338YA@2|Bacteria	2|Bacteria	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2
TLS3_k127_4441918_6	1120948.KB903217_gene1421	1.212e-87	314.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,4DY6U@85010|Pseudonocardiales	201174|Actinobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
TLS3_k127_4441918_2	1120948.KB903217_gene1422	7.624e-176	574.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4DZMU@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	GO:0008150,GO:0040007	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
TLS3_k127_4441918_4	1120948.KB903217_gene1423	9.997e-122	423.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,4DYAU@85010|Pseudonocardiales	201174|Actinobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0510	Porphobil_deam,Porphobil_deamC
TLS3_k127_4441918_0	1120948.KB903217_gene1424	5.047e-250	812.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4E0QT@85010|Pseudonocardiales	201174|Actinobacteria	H	Uroporphyrinogen-III synthase	hemD	-	2.1.1.107,4.2.1.75	ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
TLS3_k127_4441918_3	1120948.KB903217_gene1425	1.022e-166	529.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,4DX6K@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
TLS3_k127_4441918_13	103733.JNYO01000004_gene7846	1.427e-22	109.0	2F3K6@1|root,33WDH@2|Bacteria,2IQI5@201174|Actinobacteria,4E5H1@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3093
TLS3_k127_4441918_7	1380356.JNIK01000001_gene2254	4.66e-87	314.0	COG0515@1|root,COG0515@2|Bacteria,2I6W6@201174|Actinobacteria,4EXHA@85013|Frankiales	1380356.JNIK01000001_gene2254|-	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4441918_1	1120948.KB903217_gene1430	2.224e-226	743.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4DXFR@85010|Pseudonocardiales	201174|Actinobacteria	H	PFAM aminotransferase class-III	hemL	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS3_k127_4441918_5	1120948.KB903217_gene1431	1.819e-99	353.0	COG0406@1|root,COG0406@2|Bacteria,2GMXF@201174|Actinobacteria,4DY1C@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Phosphoglycerate mutase	-	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	His_Phos_1
TLS3_k127_4441918_8	1120948.KB903217_gene1432	1.464e-69	252.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria,4E3DR@85010|Pseudonocardiales	201174|Actinobacteria	CO	Thiol-disulfide isomerase-like thioredoxin	ccsX	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
TLS3_k127_4441918_14	1157632.AQWQ01000004_gene1538	1.265e-16	91.0	2ED40@1|root,3370T@2|Bacteria,2IKRT@201174|Actinobacteria	201174|Actinobacteria	S	zinc-ribbon family	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_15
TLS3_k127_4445786_1	1120948.KB903231_gene4730	3.119e-16	78.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4E0UI@85010|Pseudonocardiales	201174|Actinobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
TLS3_k127_4445786_0	1120948.KB903231_gene4729	0.0	1645.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4DXEF@85010|Pseudonocardiales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
TLS3_k127_4453810_1	1120948.KB903229_gene5235	1.062e-90	311.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2IB2S@201174|Actinobacteria,4E20B@85010|Pseudonocardiales	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
TLS3_k127_4453810_2	1120948.KB903229_gene5248	1.662e-51	192.0	COG2365@1|root,COG2365@2|Bacteria,2GK28@201174|Actinobacteria,4E6B2@85010|Pseudonocardiales	201174|Actinobacteria	T	Tyrosine phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
TLS3_k127_4453810_0	1240349.ANGC01000001_gene2492	3.15e-96	326.0	COG0542@1|root,COG0542@2|Bacteria,2GKKF@201174|Actinobacteria,4FWE1@85025|Nocardiaceae	201174|Actinobacteria	O	Clp amino terminal domain, pathogenicity island component	clpC2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Clp_N
TLS3_k127_4453810_3	675635.Psed_5520	1.373e-40	157.0	2EUDF@1|root,33MVU@2|Bacteria,2IQFI@201174|Actinobacteria,4E7DJ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4454486_0	1120948.KB903223_gene200	1.748e-106	354.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4E5QE@85010|Pseudonocardiales	201174|Actinobacteria	D	PFAM Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
TLS3_k127_4454486_1	1120948.KB903223_gene199	1.105e-43	172.0	2F9CF@1|root,341PC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4463429_5	1120948.KB903217_gene1407	1.313e-34	139.0	2DY9N@1|root,348T2@2|Bacteria,2GKWP@201174|Actinobacteria,4E6SD@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4463429_3	1120948.KB903217_gene1408	7.326e-139	445.0	COG1082@1|root,COG1082@2|Bacteria,2GJ6E@201174|Actinobacteria,4DX95@85010|Pseudonocardiales	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
TLS3_k127_4463429_4	1120948.KB903217_gene1409	8.409e-89	314.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4DZE4@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
TLS3_k127_4463429_6	1120948.KB903217_gene1410	9.053e-27	113.0	COG3311@1|root,COG3311@2|Bacteria,2GQGV@201174|Actinobacteria,4E6MN@85010|Pseudonocardiales	201174|Actinobacteria	K	TIGRFAM DNA binding domain, excisionase family	xis	-	-	-	-	-	-	-	-	-	-	-	HTH_17
TLS3_k127_4463429_0	1120948.KB903217_gene1412	3.194e-180	574.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4DYKD@85010|Pseudonocardiales	201174|Actinobacteria	GM	epimerase dehydratase	galE2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0501	Epimerase
TLS3_k127_4463429_1	1120948.KB903217_gene1413	8.163e-162	518.0	COG0204@1|root,COG0204@2|Bacteria,2GJKH@201174|Actinobacteria,4E0YI@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyltransferase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyltransferase
TLS3_k127_4463429_2	1120948.KB903217_gene1414	1.086e-147	471.0	COG0560@1|root,COG0560@2|Bacteria,2GJW9@201174|Actinobacteria,4E0EC@85010|Pseudonocardiales	201174|Actinobacteria	E	TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490	serB1	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	HAD
TLS3_k127_446796_1	1120948.KB903244_gene2929	3.436e-189	599.0	COG0454@1|root,COG1042@1|root,COG0456@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4DYY0@85010|Pseudonocardiales	201174|Actinobacteria	CK	Acyl-CoA synthetase (NDP forming)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
TLS3_k127_446796_0	1120948.KB903244_gene2930	7.611e-212	682.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4DZBB@85010|Pseudonocardiales	201174|Actinobacteria	BQ	Deacetylase, histone deacetylase acetoin utilization protein	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
TLS3_k127_446796_2	1120948.KB903244_gene2931	5.279e-101	339.0	COG2897@1|root,COG2897@2|Bacteria,2GMDR@201174|Actinobacteria,4DYEN@85010|Pseudonocardiales	201174|Actinobacteria	P	Rhodanese-related sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
TLS3_k127_446796_3	1120948.KB903244_gene2932	1.725e-13	84.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria,4DXCH@85010|Pseudonocardiales	201174|Actinobacteria	K	iron dependent repressor	ideR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
TLS3_k127_4478556_1	1120948.KB903229_gene5230	1.695e-159	517.0	COG0028@1|root,COG0028@2|Bacteria,2GN3X@201174|Actinobacteria,4DXG7@85010|Pseudonocardiales	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	mdlC	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TLS3_k127_4478556_4	1120948.KB903229_gene5229	3.615e-33	139.0	2A3MT@1|root,30S54@2|Bacteria,2HC1I@201174|Actinobacteria,4ED25@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4478556_0	1120948.KB903229_gene5228	1.164e-166	533.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4DXSS@85010|Pseudonocardiales	201174|Actinobacteria	S	hydrolase or acyltransferase of alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EHN
TLS3_k127_4478556_2	1120948.KB903217_gene1635	6.167e-148	476.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4E0DU@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_4478556_3	500153.JOEK01000020_gene2727	7.847e-52	195.0	COG1309@1|root,COG1309@2|Bacteria,2ICWK@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_4490062_3	1120948.KB903218_gene2000	9.58e-44	164.0	COG0155@1|root,COG0155@2|Bacteria,2GNUG@201174|Actinobacteria,4E275@85010|Pseudonocardiales	201174|Actinobacteria	P	Sulfite reductase, beta subunit (Hemoprotein)	cobG	-	1.14.13.83	ko:K02229	ko00860,ko01100,map00860,map01100	-	R05217	RC01979	ko00000,ko00001,ko01000	-	-	-	NIR_SIR_ferr
TLS3_k127_4490062_2	1120948.KB903218_gene1999	1.298e-104	351.0	COG2082@1|root,COG2082@2|Bacteria,2GK0B@201174|Actinobacteria,4DYTD@85010|Pseudonocardiales	201174|Actinobacteria	H	Precorrin-8X methylmutase	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
TLS3_k127_4490062_0	1120948.KB903218_gene1998	4.985e-236	750.0	COG1010@1|root,COG2243@1|root,COG1010@2|Bacteria,COG2243@2|Bacteria,2GMIR@201174|Actinobacteria,4DXB4@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the precorrin methyltransferase family	cobIJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.1.1.130,2.1.1.131	ko:K05934,ko:K13540	ko00860,ko01100,map00860,map01100	-	R03948,R05180,R05808,R05809	RC00003,RC01035,RC01293,RC01662,RC03471	ko00000,ko00001,ko01000	-	-	-	TP_methylase
TLS3_k127_4490062_5	512565.AMIS_45180	1.545e-22	111.0	2FHD0@1|root,34978@2|Bacteria,2H0SA@201174|Actinobacteria,4DK1C@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4490062_4	1068978.AMETH_4719	7.006e-39	148.0	COG3324@1|root,COG3324@2|Bacteria,2HNR6@201174|Actinobacteria,4E769@85010|Pseudonocardiales	201174|Actinobacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS3_k127_4490062_1	1172185.KB911513_gene4767	3.145e-125	422.0	COG0488@1|root,COG0619@1|root,COG0488@2|Bacteria,COG0619@2|Bacteria,2I2G4@201174|Actinobacteria	201174|Actinobacteria	P	Cobalt transport protein	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,CbiQ
TLS3_k127_4495790_2	675635.Psed_1119	5.733e-43	172.0	COG0476@1|root,COG0476@2|Bacteria,2GMJI@201174|Actinobacteria,4E1XH@85010|Pseudonocardiales	201174|Actinobacteria	H	Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
TLS3_k127_4495790_0	1120948.KB903246_gene3202	8.824e-256	792.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4DXYF@85010|Pseudonocardiales	201174|Actinobacteria	S	unusual protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
TLS3_k127_4495790_3	1120948.KB903246_gene3203	5.552e-40	151.0	2DMIS@1|root,32RVG@2|Bacteria,2IQ99@201174|Actinobacteria,4E5D2@85010|Pseudonocardiales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB7	GO:0001101,GO:0008150,GO:0010033,GO:0033993,GO:0042221,GO:0046677,GO:0050896,GO:0070542,GO:1901700	-	ko:K18958	-	-	-	-	ko00000,ko03000	-	-	-	AT_hook,Whib
TLS3_k127_4495790_1	1120948.KB903246_gene3205	3.398e-154	492.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,4DXMZ@85010|Pseudonocardiales	201174|Actinobacteria	L	helicase	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
TLS3_k127_451224_2	1120948.KB903246_gene3395	1.98e-57	204.0	COG2919@1|root,COG2919@2|Bacteria,2GQH7@201174|Actinobacteria,4E5EA@85010|Pseudonocardiales	201174|Actinobacteria	D	Septum formation initiator	divIC	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
TLS3_k127_451224_1	1120948.KB903246_gene3394	1.088e-73	260.0	COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria,4E2S8@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF501)	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
TLS3_k127_451224_0	1120948.KB903246_gene3393	1.539e-150	500.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4E04G@85010|Pseudonocardiales	201174|Actinobacteria	FP	PFAM Ppx GppA phosphatase	ppx2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
TLS3_k127_451224_3	2074.JNYD01000037_gene5110	8.907e-09	68.0	COG0053@1|root,COG0053@2|Bacteria,2GQJJ@201174|Actinobacteria,4E1ZP@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM Cation efflux	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
TLS3_k127_4518527_0	1120948.KB903243_gene2535	6.319e-109	374.0	COG0524@1|root,COG0524@2|Bacteria,2GYHF@201174|Actinobacteria,4DYH7@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM pfkB family carbohydrate kinase	scrK	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
TLS3_k127_4518527_1	1120948.KB903243_gene2536	1.628e-100	334.0	COG2017@1|root,COG2017@2|Bacteria,2GJ0H@201174|Actinobacteria,4DZ64@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Aldose 1-epimerase	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
TLS3_k127_4524603_2	1120948.KB903218_gene1847	4.958e-49	184.0	COG1309@1|root,COG1309@2|Bacteria,2GKE2@201174|Actinobacteria,4E2RY@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_4524603_1	1120948.KB903218_gene1846	1.058e-183	584.0	COG1960@1|root,COG1960@2|Bacteria,2IDR4@201174|Actinobacteria,4E8N6@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_4524603_0	1120948.KB903218_gene1845	4.367e-184	609.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4DZT6@85010|Pseudonocardiales	201174|Actinobacteria	I	Carboxyl transferase domain	yngE	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
TLS3_k127_4532512_2	1050202.KB913024_gene448	1.073e-77	263.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,408Z4@622450|Actinopolysporales	201174|Actinobacteria	EP	Oligopeptide/dipeptide transporter, C-terminal region	dppD	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
TLS3_k127_4532512_0	405948.SACE_0848	3.391e-166	537.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4DXRP@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
TLS3_k127_4532512_1	1120948.KB903246_gene3331	2.949e-104	345.0	COG2120@1|root,COG2120@2|Bacteria,2GKUM@201174|Actinobacteria,4E0WC@85010|Pseudonocardiales	201174|Actinobacteria	S	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway	mshB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016137,GO:0016138,GO:0016787,GO:0016810,GO:0016811,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	3.5.1.103	ko:K15525	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
TLS3_k127_4552159_5	1120948.KB903217_gene1373	8.276e-160	512.0	COG2733@1|root,COG2733@2|Bacteria,2GKGM@201174|Actinobacteria,4DYTZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
TLS3_k127_4552159_1	675635.Psed_6436	1.043e-269	873.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4EF7J@85010|Pseudonocardiales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
TLS3_k127_4552159_4	675635.Psed_6435	8.636e-201	643.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
TLS3_k127_4552159_3	981369.JQMJ01000004_gene4964	1.18e-201	640.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,2NKD9@228398|Streptacidiphilus	201174|Actinobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD_5
TLS3_k127_4552159_9	1122611.KB903940_gene1936	7.935e-35	138.0	COG0662@1|root,COG0662@2|Bacteria,2I36W@201174|Actinobacteria,4ER7R@85012|Streptosporangiales	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4552159_2	1120948.KB903217_gene1372	1.82e-223	702.0	COG3852@1|root,COG3852@2|Bacteria,2I3H8@201174|Actinobacteria,4EDWI@85010|Pseudonocardiales	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
TLS3_k127_4552159_0	1120948.KB903217_gene1371	9.384e-272	846.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,2GK62@201174|Actinobacteria,4E11F@85010|Pseudonocardiales	201174|Actinobacteria	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,Response_reg
TLS3_k127_4552159_7	1123023.JIAI01000015_gene3232	4.802e-78	281.0	COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria,4E0EP@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the peptidase S8 family	mycP4	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009405,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0031224,GO:0031226,GO:0032879,GO:0040007,GO:0043170,GO:0044238,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0051046,GO:0051049,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	-	ko:K14743	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
TLS3_k127_4552159_6	1123024.AUII01000025_gene2108	2.492e-114	376.0	COG0388@1|root,COG0388@2|Bacteria,2GMSD@201174|Actinobacteria,4E2I6@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
TLS3_k127_4552159_8	1463900.JOIX01000035_gene3758	1.983e-40	153.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria	201174|Actinobacteria	J	Phenazine biosynthesis protein PhzF	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
TLS3_k127_4557871_9	391612.CY0110_03479	3.516e-37	145.0	COG4829@1|root,COG4829@2|Bacteria,1G8MH@1117|Cyanobacteria,3KJYU@43988|Cyanothece	1117|Cyanobacteria	Q	Muconolactone delta-isomerase	-	-	5.3.3.4	ko:K03464	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R06990	RC01109	ko00000,ko00001,ko00002,ko01000	-	-	-	MIase
TLS3_k127_4557871_7	1120948.KB903217_gene1636	8.006e-57	199.0	2F96G@1|root,341HX@2|Bacteria,2IT8Z@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4557871_0	1120948.KB903246_gene3357	4.615e-199	625.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4DYTA@85010|Pseudonocardiales	201174|Actinobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
TLS3_k127_4557871_8	1206732.BAGD01000106_gene4725	8.79e-48	178.0	COG0350@1|root,COG0350@2|Bacteria,2IHP1@201174|Actinobacteria,4G0JF@85025|Nocardiaceae	201174|Actinobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ada	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
TLS3_k127_4557871_3	2074.JNYD01000005_gene3252	3.477e-119	406.0	COG1322@1|root,COG1322@2|Bacteria,2GP4U@201174|Actinobacteria,4DZEY@85010|Pseudonocardiales	201174|Actinobacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
TLS3_k127_4557871_11	1120948.KB903246_gene3360	9.255e-33	138.0	2FH0D@1|root,348VF@2|Bacteria,2I8QN@201174|Actinobacteria,4E3NY@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4557871_10	103733.JNYO01000008_gene5487	8.614e-34	137.0	2E5KE@1|root,330BK@2|Bacteria,2IKV9@201174|Actinobacteria,4E4BN@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4557871_5	211114.JOEF01000001_gene7246	8.77e-97	339.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4DYVZ@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_4557871_2	103733.JNYO01000008_gene5482	1.908e-127	433.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4DYCS@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TLS3_k127_4557871_1	1120948.KB903246_gene3361	3.875e-182	572.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4DX3Z@85010|Pseudonocardiales	201174|Actinobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
TLS3_k127_4557871_6	1120948.KB903246_gene3362	7.89e-65	228.0	2EATU@1|root,334VK@2|Bacteria,2IKQC@201174|Actinobacteria,4E3S6@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4557871_4	1120948.KB903246_gene3363	1.859e-101	346.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,4DXSV@85010|Pseudonocardiales	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
TLS3_k127_4558146_5	1120948.KB903229_gene4960	9.748e-35	134.0	COG1793@1|root,COG3275@1|root,COG1793@2|Bacteria,COG3275@2|Bacteria,2IKE5@201174|Actinobacteria,4E2E9@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,His_kinase,LigD_N
TLS3_k127_4558146_1	1120948.KB903229_gene4962	7.476e-76	268.0	2CF7S@1|root,2ZB6P@2|Bacteria,2H77W@201174|Actinobacteria,4ECRE@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4558146_3	1068980.ARVW01000001_gene7015	7.201e-60	233.0	COG1522@1|root,COG1940@1|root,COG1522@2|Bacteria,COG1940@2|Bacteria,2GJ3W@201174|Actinobacteria,4E4PX@85010|Pseudonocardiales	201174|Actinobacteria	K	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
TLS3_k127_4558146_0	1120948.KB903229_gene4963	4.883e-154	498.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,4E33B@85010|Pseudonocardiales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_4558146_2	1120948.KB903229_gene4964	2.904e-71	249.0	2DR5D@1|root,33A8R@2|Bacteria,2H3Y4@201174|Actinobacteria,4E41S@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2993)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2993
TLS3_k127_4558146_4	1120948.KB903229_gene4967	1.817e-42	155.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4DY91@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
TLS3_k127_4566495_2	1120948.KB903231_gene4727	1.317e-106	372.0	COG0566@1|root,COG0566@2|Bacteria,2GNJK@201174|Actinobacteria,4DYV5@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
TLS3_k127_4566495_0	1120948.KB903231_gene4726	5.559e-267	827.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4DZCT@85010|Pseudonocardiales	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	tgs3	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
TLS3_k127_4566495_1	1120948.KB903231_gene4725	3.73e-118	389.0	COG1752@1|root,COG1752@2|Bacteria,2IB0F@201174|Actinobacteria,4E2Z4@85010|Pseudonocardiales	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
TLS3_k127_4566495_3	1120948.KB903231_gene4724	1.012e-36	149.0	2DRWJ@1|root,32URV@2|Bacteria,2IFAY@201174|Actinobacteria,4E3JI@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4572285_15	1120948.KB903245_gene3668	8.442e-54	190.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,4DX4E@85010|Pseudonocardiales	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
TLS3_k127_4572285_8	926564.KI911710_gene2831	1.731e-128	420.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	moeY	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,ThiF
TLS3_k127_4572285_3	926564.KI911710_gene2832	2.752e-185	610.0	COG1541@1|root,COG1541@2|Bacteria	2|Bacteria	H	phenylacetate-CoA ligase activity	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
TLS3_k127_4572285_19	1120948.KB903245_gene3665	5.525e-34	133.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4E5FG@85010|Pseudonocardiales	201174|Actinobacteria	J	Binds the 23S rRNA	rpmE	GO:0008150,GO:0040007	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
TLS3_k127_4572285_6	1120948.KB903245_gene3664	1.975e-175	556.0	COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria,4DXDH@85010|Pseudonocardiales	201174|Actinobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0008150,GO:0040007	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
TLS3_k127_4572285_13	1120948.KB903245_gene3663	5.328e-89	317.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4DXKY@85010|Pseudonocardiales	201174|Actinobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
TLS3_k127_4572285_17	2074.JNYD01000031_gene6580	3.846e-48	190.0	COG0454@1|root,COG0456@2|Bacteria,2I9Y3@201174|Actinobacteria,4E6FQ@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
TLS3_k127_4572285_10	58123.JOFJ01000014_gene5158	3.257e-112	398.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EH80@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
TLS3_k127_4572285_12	1123023.JIAI01000013_gene3990	1.247e-94	314.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,4DY0G@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the SUA5 family	ywlC	GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
TLS3_k127_4572285_2	1120948.KB903245_gene3658	7.419e-248	768.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4DZ2J@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
TLS3_k127_4572285_4	1120948.KB903245_gene3657	1.521e-181	574.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4DZ4G@85010|Pseudonocardiales	201174|Actinobacteria	M	UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase	rfe	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
TLS3_k127_4572285_9	1120948.KB903245_gene3655	9.572e-119	392.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4DYUM@85010|Pseudonocardiales	201174|Actinobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
TLS3_k127_4572285_20	1120948.KB903245_gene3654	3.881e-28	117.0	COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria,4E6GB@85010|Pseudonocardiales	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
TLS3_k127_4572285_16	1120948.KB903245_gene3653	3.424e-48	179.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4E2Q8@85010|Pseudonocardiales	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
TLS3_k127_4572285_11	1120948.KB903245_gene3652	2.799e-102	349.0	COG0712@1|root,COG0712@2|Bacteria,2GMJ5@201174|Actinobacteria,4DXBG@85010|Pseudonocardiales	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
TLS3_k127_4572285_0	1120948.KB903245_gene3651	7.488e-311	959.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4E0X3@85010|Pseudonocardiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
TLS3_k127_4572285_7	1120948.KB903245_gene3650	8.611e-134	434.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4DXM0@85010|Pseudonocardiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
TLS3_k127_4572285_1	1120948.KB903245_gene3649	1.243e-280	880.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4DX8E@85010|Pseudonocardiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
TLS3_k127_4572285_18	1120948.KB903245_gene3648	1.329e-41	168.0	COG0355@1|root,COG0355@2|Bacteria,2IHNZ@201174|Actinobacteria,4E4C5@85010|Pseudonocardiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
TLS3_k127_4572285_14	1120948.KB903245_gene3647	2.08e-54	197.0	2E6YX@1|root,331I5@2|Bacteria,2IFIG@201174|Actinobacteria,4E3TM@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2550)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2550
TLS3_k127_4572285_5	1445613.JALM01000070_gene6519	9.784e-178	566.0	COG0277@1|root,COG0277@2|Bacteria,2GJ33@201174|Actinobacteria,4DXE5@85010|Pseudonocardiales	201174|Actinobacteria	C	FAD-linked oxidoreductase	gulo	-	1.1.3.8	ko:K00103	ko00053,ko01100,map00053,map01100	M00129	R00647,R03184,R10053	RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
TLS3_k127_458895_1	1120948.KB903248_gene4304	3.488e-93	310.0	COG1647@1|root,COG1647@2|Bacteria,2GM1Y@201174|Actinobacteria,4DZX1@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM alpha beta hydrolase fold	yvaK	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
TLS3_k127_458895_0	1120948.KB903248_gene4306	1.901e-131	428.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4DYXS@85010|Pseudonocardiales	201174|Actinobacteria	GK	glucokinase	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
TLS3_k127_46132_3	391037.Sare_4669	9.567e-35	136.0	COG0398@1|root,COG0398@2|Bacteria,2GN68@201174|Actinobacteria,4DEI2@85008|Micromonosporales	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
TLS3_k127_46132_0	1288083.AUKR01000007_gene3353	6.487e-198	639.0	COG0535@1|root,COG0535@2|Bacteria,2HP1A@201174|Actinobacteria	201174|Actinobacteria	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_46132_2	67267.JNXT01000017_gene7224	3.54e-70	263.0	COG1215@1|root,COG1215@2|Bacteria,2I9RN@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_46132_1	67267.JNXT01000017_gene7225	8.392e-90	302.0	COG0535@1|root,COG0639@1|root,COG0535@2|Bacteria,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	4.3.1.30	ko:K13309	ko00523,ko01130,map00523,map01130	M00797	R08583	RC02360	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_14,Metallophos_2,Radical_SAM,SPASM
TLS3_k127_46252_1	1169161.KB897733_gene600	5.462e-55	198.0	COG0500@1|root,COG2226@2|Bacteria,2I36Q@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_46252_2	1449353.JQMQ01000005_gene1312	2.589e-39	160.0	COG4635@1|root,COG4635@2|Bacteria,2IQCQ@201174|Actinobacteria,2NMMB@228398|Streptacidiphilus	201174|Actinobacteria	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
TLS3_k127_46252_0	1160137.KB907307_gene1494	1.61e-203	663.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4FU7Y@85025|Nocardiaceae	201174|Actinobacteria	P	PFAM E1-E2 ATPase-associated domain protein, Haloacid dehalogenase domain protein hydrolase, cation transporting ATPase domain protein	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
TLS3_k127_46252_4	1172188.KB911824_gene3347	1.795e-21	102.0	2EC60@1|root,3364M@2|Bacteria,2GR61@201174|Actinobacteria,4FK1U@85021|Intrasporangiaceae	201174|Actinobacteria	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
TLS3_k127_46252_7	457425.XNR_0116	0.0003135	50.0	2FKX7@1|root,34CHF@2|Bacteria,2GSNQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_46252_6	1068978.AMETH_3660	8.589e-07	60.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria,4E6RZ@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_46252_3	1137268.AZXF01000005_gene3065	7.023e-26	120.0	2DNU1@1|root,32Z4S@2|Bacteria,2I3QM@201174|Actinobacteria	201174|Actinobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
TLS3_k127_46252_5	1123023.JIAI01000047_gene9260	3.541e-17	87.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria,4E1FZ@85010|Pseudonocardiales	201174|Actinobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppsA	-	2.7.9.2	ko:K01007,ko:K21787	ko00333,ko00620,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00333,map00620,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00374,M00837,M00838	R00199,R11662,R11673	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
TLS3_k127_4633171_3	1121272.KB903254_gene6710	5.809e-22	101.0	COG1403@1|root,COG1403@2|Bacteria,2INVR@201174|Actinobacteria	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
TLS3_k127_4633171_4	1120948.KB903244_gene3066	1.614e-10	72.0	2C038@1|root,347CF@2|Bacteria,2GWPX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4633171_0	1120948.KB903244_gene3081	5.825e-219	692.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,4E9P5@85010|Pseudonocardiales	201174|Actinobacteria	C	FAD binding domain	menJ	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016491,GO:0016627,GO:0030312,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
TLS3_k127_4633171_1	1120948.KB903244_gene3065	7.834e-136	438.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4DZ6C@85010|Pseudonocardiales	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
TLS3_k127_4633171_2	1123024.AUII01000001_gene2869	4.361e-74	251.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4DZQA@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
TLS3_k127_4653704_6	1120948.KB903224_gene329	1.155e-20	92.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4DXG2@85010|Pseudonocardiales	201174|Actinobacteria	C	Malic enzyme	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
TLS3_k127_4653704_3	1123024.AUII01000005_gene2387	8.069e-47	185.0	COG2068@1|root,COG2068@2|Bacteria,2GK5R@201174|Actinobacteria,4E42U@85010|Pseudonocardiales	201174|Actinobacteria	S	MobA-like NTP transferase domain	nboR	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
TLS3_k127_4653704_4	1120948.KB903224_gene331	3.698e-26	109.0	2C7NN@1|root,33FDU@2|Bacteria,2GR44@201174|Actinobacteria,4E7E5@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4653704_0	1179773.BN6_05050	1.531e-214	707.0	COG2378@1|root,COG2378@2|Bacteria,2GURQ@201174|Actinobacteria,4DYGK@85010|Pseudonocardiales	201174|Actinobacteria	K	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
TLS3_k127_4653704_1	1120948.KB903224_gene333	1.225e-111	362.0	COG2229@1|root,COG2229@2|Bacteria,2GJIT@201174|Actinobacteria,4DXCN@85010|Pseudonocardiales	201174|Actinobacteria	S	ATP binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
TLS3_k127_4653704_5	1463864.JOGO01000010_gene3314	7.05e-22	104.0	COG1846@1|root,COG1846@2|Bacteria,2II46@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function (DUF742)	-	-	-	-	-	-	-	-	-	-	-	-	DUF742
TLS3_k127_4653704_2	1120948.KB903224_gene335	4.13e-77	263.0	COG2018@1|root,COG2018@2|Bacteria,2IFB7@201174|Actinobacteria,4E2K7@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Roadblock LC7	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
TLS3_k127_4653704_7	1120948.KB903224_gene336	8.23e-12	67.0	COG4251@1|root,COG5263@1|root,COG4251@2|Bacteria,COG5263@2|Bacteria,2GK6E@201174|Actinobacteria,4DX42@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
TLS3_k127_4732038_4	29306.JOBE01000008_gene4679	3.873e-08	55.0	COG0790@1|root,COG0790@2|Bacteria,2GKCE@201174|Actinobacteria	201174|Actinobacteria	KLT	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Sel1,TPR_10,TPR_16,TPR_4
TLS3_k127_4732038_0	1120948.KB903246_gene3197	0.0	1178.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4E04T@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Uncharacterised protein family UPF0182	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
TLS3_k127_4732038_2	1120948.KB903246_gene3198	4.508e-140	458.0	COG3480@1|root,COG3480@2|Bacteria,2GJDD@201174|Actinobacteria,4DYAZ@85010|Pseudonocardiales	201174|Actinobacteria	T	Belongs to the peptidase S16 family	lon	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
TLS3_k127_4732038_1	1120948.KB903246_gene3199	5.854e-213	681.0	COG5282@1|root,COG5282@2|Bacteria,2GJ9K@201174|Actinobacteria,4E0U4@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Uncharacterised conserved protein (DUF2342)	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
TLS3_k127_4732038_3	1120948.KB903246_gene3200	1.424e-80	275.0	COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria,4E307@85010|Pseudonocardiales	201174|Actinobacteria	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
TLS3_k127_4739181_0	1155714.KB891993_gene5747	5.405e-162	537.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_11,Methyltransf_12,Methyltransf_25,PP-binding
TLS3_k127_4761104_8	1120948.KB903243_gene2566	1.117e-19	92.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4EAYA@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TLS3_k127_4761104_7	1120948.KB903243_gene2565	3.992e-31	126.0	COG2197@1|root,COG2197@2|Bacteria,2GM61@201174|Actinobacteria,4EBPI@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_4761104_3	1120948.KB903218_gene1980	3.217e-84	291.0	COG1075@1|root,COG1075@2|Bacteria,2GJGC@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,PGAP1
TLS3_k127_4761104_1	1120948.KB903218_gene1981	2.317e-133	435.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4E12C@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.33	ko:K00218	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03845,R06286	RC01008	ko00000,ko00001,ko01000	-	-	-	adh_short
TLS3_k127_4761104_0	1120948.KB903218_gene1986	2.008e-161	517.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,2GM8G@201174|Actinobacteria,4DXTS@85010|Pseudonocardiales	201174|Actinobacteria	H	Precorrin-6Y C5,15-methyltransferase (Decarboxylating)	cobL	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.1.1.132	ko:K00595	ko00860,ko01100,map00860,map01100	-	R05149	RC00003,RC01279	ko00000,ko00001,ko01000	-	-	iNJ661.Rv2072c	PCMT,TP_methylase
TLS3_k127_4761104_2	1120948.KB903218_gene1987	4.44e-123	411.0	COG2875@1|root,COG2875@2|Bacteria,2GJ97@201174|Actinobacteria,4DXAP@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the precorrin methyltransferase family	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
TLS3_k127_4761104_4	526225.Gobs_0566	1.772e-68	251.0	COG2099@1|root,COG2099@2|Bacteria,2GMYZ@201174|Actinobacteria,4ESJP@85013|Frankiales	201174|Actinobacteria	H	PFAM Precorrin-6x reductase CbiJ CobK	cobK	-	1.3.1.106,1.3.1.54	ko:K05895	ko00860,ko01100,map00860,map01100	-	R05150,R05812	RC01280	ko00000,ko00001,ko01000	-	-	-	CbiJ
TLS3_k127_4761104_5	1151061.CAJY01000040_gene4066	2.225e-54	205.0	COG0488@1|root,COG0619@1|root,COG4241@1|root,COG0488@2|Bacteria,COG0619@2|Bacteria,COG4241@2|Bacteria,2I2G4@201174|Actinobacteria	201174|Actinobacteria	P	Cobalt transport protein	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,CbiQ
TLS3_k127_4790703_0	1120948.KB903217_gene1169	2.233e-228	722.0	COG0053@1|root,COG0053@2|Bacteria,2GYZA@201174|Actinobacteria,4DZGW@85010|Pseudonocardiales	201174|Actinobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4796348_5	1120948.KB903217_gene1233	1.126e-135	437.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria,4DYW2@85010|Pseudonocardiales	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
TLS3_k127_4796348_6	1120948.KB903217_gene1234	7.076e-127	427.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4DYCB@85010|Pseudonocardiales	201174|Actinobacteria	P	transport system	pstA	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
TLS3_k127_4796348_4	1120948.KB903217_gene1235	1.802e-149	491.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4DY3N@85010|Pseudonocardiales	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
TLS3_k127_4796348_7	1120948.KB903217_gene1236	5.384e-117	379.0	COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,4DYKU@85010|Pseudonocardiales	201174|Actinobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0016020,GO:0019220,GO:0019222,GO:0022611,GO:0031323,GO:0031324,GO:0032502,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042221,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044444,GO:0044464,GO:0045936,GO:0046677,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:0071944,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
TLS3_k127_4796348_3	1120948.KB903217_gene1237	7.979e-167	553.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4E00G@85010|Pseudonocardiales	201174|Actinobacteria	K	TIGRFAM cell envelope-related function transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
TLS3_k127_4796348_8	1120948.KB903217_gene1239	1.89e-95	330.0	COG2199@1|root,COG2199@2|Bacteria,2I5FH@201174|Actinobacteria,4EDYW@85010|Pseudonocardiales	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
TLS3_k127_4796348_1	1120948.KB903217_gene1241	8.342e-210	671.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4DZKY@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090	-	-	-	-	-	-	-	-	-	-	Dus
TLS3_k127_4796348_0	1120948.KB903217_gene1242	2.901e-320	986.0	COG2146@1|root,COG2220@1|root,COG2146@2|Bacteria,COG2220@2|Bacteria,2GP4N@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	ko:K14952	ko05152,map05152	-	-	-	ko00000,ko00001	-	-	-	Lactamase_B_3,Rieske
TLS3_k127_4796348_2	1120948.KB903217_gene1243	3.799e-189	598.0	COG1387@1|root,COG1387@2|Bacteria,2GMFH@201174|Actinobacteria,4DYHB@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM PHP domain	polX	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	HHH_8,PHP
TLS3_k127_4796348_9	1120948.KB903224_gene298	1.23e-92	308.0	COG0640@1|root,COG3832@1|root,COG0640@2|Bacteria,COG3832@2|Bacteria,2GNW2@201174|Actinobacteria,4E1UR@85010|Pseudonocardiales	201174|Actinobacteria	K	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20
TLS3_k127_4797961_1	1120948.KB903248_gene4339	6.203e-194	613.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4DXZ6@85010|Pseudonocardiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
TLS3_k127_4797961_5	1120948.KB903248_gene4338	9.76e-66	245.0	COG1917@1|root,COG1917@2|Bacteria,2IIQD@201174|Actinobacteria,4E5D9@85010|Pseudonocardiales	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_4797961_6	2074.JNYD01000013_gene6970	1.283e-64	226.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,VCBS
TLS3_k127_4797961_4	1120948.KB903229_gene5053	5.659e-100	332.0	COG5587@1|root,COG5587@2|Bacteria,2IJG5@201174|Actinobacteria,4E0G4@85010|Pseudonocardiales	201174|Actinobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
TLS3_k127_4797961_2	134676.ACPL_4764	4.29e-148	482.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4DAXK@85008|Micromonosporales	201174|Actinobacteria	EK	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_4797961_0	1120948.KB903248_gene4337	5.014e-204	639.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4DXKG@85010|Pseudonocardiales	201174|Actinobacteria	E	Branched-chain amino acid aminotransferase	ilvE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0006082,GO:0006464,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018065,GO:0018193,GO:0018205,GO:0018272,GO:0018352,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0036211,GO:0040007,GO:0043094,GO:0043102,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071265,GO:0071267,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
TLS3_k127_4797961_7	675635.Psed_4560	6.218e-57	212.0	COG0368@1|root,COG0368@2|Bacteria,2GKM4@201174|Actinobacteria,4E2M6@85010|Pseudonocardiales	201174|Actinobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
TLS3_k127_4797961_3	1120948.KB903248_gene4335	7.159e-102	341.0	COG2038@1|root,COG2038@2|Bacteria,2GJ16@201174|Actinobacteria,4DX78@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2207	CobU,DBI_PRT
TLS3_k127_4801192_1	2074.JNYD01000019_gene2436	3.256e-87	294.0	2BGH6@1|root,32AF9@2|Bacteria,2IR8N@201174|Actinobacteria,4EBCX@85010|Pseudonocardiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
TLS3_k127_4801192_2	1323361.JPOC01000048_gene409	7.116e-77	269.0	COG2141@1|root,COG2141@2|Bacteria,2GMUP@201174|Actinobacteria,4G2UX@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_4801192_0	2074.JNYD01000019_gene2435	2.05e-154	501.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4DZQQ@85010|Pseudonocardiales	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
TLS3_k127_4801192_3	43354.JOIJ01000002_gene4497	2.513e-61	216.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,4E2K4@85010|Pseudonocardiales	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
TLS3_k127_4801227_2	222534.KB893750_gene4365	3.244e-36	147.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_4801227_0	1380356.JNIK01000001_gene2071	1.137e-89	305.0	COG0426@1|root,COG0426@2|Bacteria,2GKJ9@201174|Actinobacteria,4ESHY@85013|Frankiales	201174|Actinobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4801227_1	1246448.ANAZ01000002_gene3798	8.958e-69	242.0	2A651@1|root,30UXH@2|Bacteria,2IERM@201174|Actinobacteria	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
TLS3_k127_4801227_3	1254432.SCE1572_29915	6.195e-32	132.0	COG2259@1|root,31BQE@2|Bacteria,1P7BF@1224|Proteobacteria,4355C@68525|delta/epsilon subdivisions,2WZG9@28221|Deltaproteobacteria,2Z22W@29|Myxococcales	28221|Deltaproteobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
TLS3_k127_4813342_1	42256.RradSPS_1883	2.242e-84	292.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4CSXQ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
TLS3_k127_4813342_0	1120948.KB903229_gene4960	3.042e-220	716.0	COG1793@1|root,COG3275@1|root,COG1793@2|Bacteria,COG3275@2|Bacteria,2IKE5@201174|Actinobacteria,4E2E9@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,His_kinase,LigD_N
TLS3_k127_4815084_11	1120948.KB903244_gene2898	2.431e-27	113.0	COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,4DXNM@85010|Pseudonocardiales	201174|Actinobacteria	L	Type III restriction enzyme, res subunit	sdrA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ResIII
TLS3_k127_4815084_12	675635.Psed_2993	7.075e-27	114.0	2E39Y@1|root,32Y9G@2|Bacteria,2GQJA@201174|Actinobacteria,4E6PA@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4815084_2	1120948.KB903244_gene2896	1.76e-205	648.0	COG0174@1|root,COG0174@2|Bacteria,2GJ83@201174|Actinobacteria,4DXQ7@85010|Pseudonocardiales	201174|Actinobacteria	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N_2
TLS3_k127_4815084_5	1120948.KB903244_gene2892	7.839e-99	329.0	COG1218@1|root,COG1218@2|Bacteria,2GMW7@201174|Actinobacteria,4E1CV@85010|Pseudonocardiales	201174|Actinobacteria	P	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
TLS3_k127_4815084_8	1120948.KB903245_gene3555	1.982e-42	158.0	arCOG03092@1|root,32YMQ@2|Bacteria,2I3JS@201174|Actinobacteria,4E63Y@85010|Pseudonocardiales	201174|Actinobacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure	gvpA	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
TLS3_k127_4815084_1	405948.SACE_1932	1.543e-250	775.0	COG2421@1|root,COG2421@2|Bacteria,2HQSF@201174|Actinobacteria,4DZKN@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Acetamidase Formamidase	-	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
TLS3_k127_4815084_6	882082.SaccyDRAFT_0430	1.306e-75	262.0	29DTM@1|root,300RH@2|Bacteria,2HYGI@201174|Actinobacteria,4EAT4@85010|Pseudonocardiales	201174|Actinobacteria	S	AmiS/UreI family transporter	amiS	-	-	ko:K22112	-	-	-	-	ko00000,ko02000	1.A.29.1.1,1.A.29.1.2,1.A.29.1.6	-	-	AmiS_UreI
TLS3_k127_4815084_13	882082.SaccyDRAFT_2640	2.359e-12	74.0	COG2331@1|root,COG2331@2|Bacteria,2HNXF@201174|Actinobacteria,4E7E4@85010|Pseudonocardiales	201174|Actinobacteria	S	Regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
TLS3_k127_4815084_0	2074.JNYD01000017_gene4296	0.0	1230.0	COG2909@1|root,COG2909@2|Bacteria,2I999@201174|Actinobacteria,4EEDN@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_4815084_3	2074.JNYD01000017_gene4294	9.597e-139	457.0	2F92T@1|root,341EE@2|Bacteria,2GPMN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4815084_4	1120948.KB903244_gene2885	5.103e-101	329.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4DYGX@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS3_k127_4832713_0	1120948.KB903229_gene5274	8.157e-229	719.0	COG1012@1|root,COG1012@2|Bacteria,2H5M9@201174|Actinobacteria,4DY5D@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.39,1.2.1.79	ko:K00135,ko:K00146	ko00250,ko00310,ko00350,ko00360,ko00643,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00360,map00643,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401,R02536	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_4832713_1	1120948.KB903229_gene5273	7.579e-89	304.0	COG4221@1|root,COG4221@2|Bacteria,2GP05@201174|Actinobacteria,4E41N@85010|Pseudonocardiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_4832908_1	1120948.KB903246_gene3255	1.486e-141	454.0	COG2334@1|root,COG2334@2|Bacteria,2HCIQ@201174|Actinobacteria,4DZ7Q@85010|Pseudonocardiales	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4832908_5	1120948.KB903243_gene2509	1.34e-64	226.0	COG1513@1|root,COG1513@2|Bacteria,2GVEH@201174|Actinobacteria,4E514@85010|Pseudonocardiales	201174|Actinobacteria	P	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide	cynS	-	4.2.1.104	ko:K01725	ko00910,map00910	-	R03546,R10079	RC00952	ko00000,ko00001,ko01000	-	-	-	Cyanate_lyase
TLS3_k127_4832908_3	1120948.KB903246_gene3256	6.43e-127	413.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4DYA4@85010|Pseudonocardiales	201174|Actinobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0008150,GO:0040007	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0553	MR_MLE_C
TLS3_k127_4832908_2	1120948.KB903246_gene3257	3.462e-127	418.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4DYFK@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	menE	GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007	4.2.1.113,6.2.1.26	ko:K01911,ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030,R04031	RC00004,RC00014,RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_4832908_6	1236902.ANAS01000047_gene2277	1.136e-13	83.0	COG3070@1|root,COG3070@2|Bacteria,2IKKV@201174|Actinobacteria	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
TLS3_k127_4832908_0	1120948.KB903246_gene3259	1.899e-167	552.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4E09A@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily	menB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576,GO:1901661,GO:1901663	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
TLS3_k127_4832908_4	208439.AJAP_38045	5.038e-94	313.0	COG0053@1|root,COG0053@2|Bacteria,2GQJJ@201174|Actinobacteria,4E1ZP@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM Cation efflux	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
TLS3_k127_4843784_1	330084.JNYZ01000012_gene7963	4.456e-34	141.0	COG2197@1|root,COG2197@2|Bacteria,2GN46@201174|Actinobacteria,4DXJI@85010|Pseudonocardiales	201174|Actinobacteria	K	Response regulator receiver domain	bldM	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_4843784_2	1380393.JHVP01000004_gene401	2.058e-27	115.0	COG5416@1|root,COG5416@2|Bacteria,2HD5K@201174|Actinobacteria	201174|Actinobacteria	S	Lipopolysaccharide assembly protein A domain	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
TLS3_k127_4843784_0	2074.JNYD01000015_gene4543	2.536e-220	708.0	COG2909@1|root,COG2909@2|Bacteria,2HEKA@201174|Actinobacteria,4EAS6@85010|Pseudonocardiales	201174|Actinobacteria	K	ATP-dependent transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
TLS3_k127_4869239_0	1120948.KB903217_gene1168	2.258e-315	980.0	COG0433@1|root,COG0433@2|Bacteria,2GMYE@201174|Actinobacteria,4DZQ7@85010|Pseudonocardiales	201174|Actinobacteria	L	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
TLS3_k127_4904381_1	1120948.KB903246_gene3418	2.555e-41	169.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
TLS3_k127_4904381_0	1120948.KB903246_gene3419	5.469e-134	448.0	COG3103@1|root,COG4991@2|Bacteria,2IA2V@201174|Actinobacteria,4DZ1K@85010|Pseudonocardiales	201174|Actinobacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4904381_2	1120948.KB903246_gene3420	1.668e-28	127.0	2EI5Z@1|root,33BXC@2|Bacteria	2|Bacteria	S	Polysaccharide lyase	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4,Polysacc_lyase
TLS3_k127_4910562_2	1120948.KB903218_gene1871	6.765e-84	282.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4DY68@85010|Pseudonocardiales	201174|Actinobacteria	C	FAD linked	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
TLS3_k127_4910562_4	1120948.KB903218_gene1873	1.159e-45	168.0	COG3411@1|root,COG3411@2|Bacteria,2IM8K@201174|Actinobacteria,4E5KP@85010|Pseudonocardiales	201174|Actinobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4910562_0	1120948.KB903218_gene1874	2.121e-152	488.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4E10J@85010|Pseudonocardiales	201174|Actinobacteria	E	Glucose dehydrogenase C-terminus	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_4910562_3	1120948.KB903218_gene2135	2.1e-74	269.0	2C7GR@1|root,32H51@2|Bacteria,2IPDA@201174|Actinobacteria,4E65R@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4910562_1	1120948.KB903229_gene5067	9.904e-87	291.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4DYEF@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_4919156_3	1120948.KB903224_gene348	3.73e-24	108.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4E0VT@85010|Pseudonocardiales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0035601,GO:0036211,GO:0040007,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0098732,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
TLS3_k127_4919156_2	1120948.KB903224_gene347	1.378e-43	161.0	2CUM0@1|root,32SVJ@2|Bacteria,2IQG7@201174|Actinobacteria,4E5G8@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3263
TLS3_k127_4919156_1	1120948.KB903224_gene346	1.644e-53	199.0	2DP6P@1|root,330SA@2|Bacteria,2IIM6@201174|Actinobacteria,4E53H@85010|Pseudonocardiales	201174|Actinobacteria	S	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C
TLS3_k127_4919156_0	882083.SacmaDRAFT_4809	1.8e-247	781.0	COG0464@1|root,COG1222@1|root,COG0464@2|Bacteria,COG1222@2|Bacteria,2GJNW@201174|Actinobacteria,4DX64@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the AAA ATPase family	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_N
TLS3_k127_49213_6	1120948.KB903217_gene1186	7.424e-98	323.0	COG1595@1|root,COG1595@2|Bacteria,2GKFQ@201174|Actinobacteria,4DXVP@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS3_k127_49213_2	1120948.KB903217_gene1187	1.438e-201	640.0	COG0191@1|root,COG0191@2|Bacteria,2GM5P@201174|Actinobacteria,4DZK9@85010|Pseudonocardiales	201174|Actinobacteria	G	fructose-bisphosphate aldolase, class II, yeast E. coli subtype	fba	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
TLS3_k127_49213_10	1120948.KB903217_gene1188	1.474e-61	215.0	2BG1F@1|root,329XM@2|Bacteria,2I8BC@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3151)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3151
TLS3_k127_49213_7	2074.JNYD01000004_gene4698	1.049e-86	299.0	COG4129@1|root,COG4129@2|Bacteria,2GIR7@201174|Actinobacteria,4DYDP@85010|Pseudonocardiales	201174|Actinobacteria	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
TLS3_k127_49213_12	1120948.KB903217_gene1190	3.858e-56	205.0	COG1597@1|root,COG1597@2|Bacteria,2IFXY@201174|Actinobacteria,4E2PN@85010|Pseudonocardiales	201174|Actinobacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_49213_0	1120948.KB903217_gene1191	3.025e-240	767.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4DZBP@85010|Pseudonocardiales	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
TLS3_k127_49213_14	1120948.KB903217_gene1192	4.737e-30	125.0	COG5207@1|root,COG5207@2|Bacteria,2IKW9@201174|Actinobacteria,4E5S8@85010|Pseudonocardiales	201174|Actinobacteria	O	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
TLS3_k127_49213_5	211114.JOEF01000009_gene1686	2.178e-120	400.0	COG0584@1|root,COG0584@2|Bacteria,2GM8K@201174|Actinobacteria,4DX6D@85010|Pseudonocardiales	201174|Actinobacteria	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
TLS3_k127_49213_3	1120948.KB903217_gene1194	9.542e-200	629.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4DX77@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the GARS family	purD	GO:0008150,GO:0040007	6.3.3.1,6.3.4.13	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
TLS3_k127_49213_11	1120948.KB903217_gene1196	4.661e-60	232.0	COG3953@1|root,COG3953@2|Bacteria,2HBQA@201174|Actinobacteria,4DYK3@85010|Pseudonocardiales	201174|Actinobacteria	N	Belongs to the WXG100 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4226,SLT,WXG100
TLS3_k127_49213_13	1120948.KB903217_gene1196	9.183e-49	188.0	COG3953@1|root,COG3953@2|Bacteria,2HBQA@201174|Actinobacteria,4DYK3@85010|Pseudonocardiales	201174|Actinobacteria	N	Belongs to the WXG100 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4226,SLT,WXG100
TLS3_k127_49213_1	1120948.KB903217_gene1197	6.06e-215	671.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4DY9I@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Aminotransferase class I and II	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_49213_9	2074.JNYD01000020_gene2642	1.908e-65	237.0	COG1226@1|root,COG1226@2|Bacteria,2GKNF@201174|Actinobacteria,4E03Y@85010|Pseudonocardiales	201174|Actinobacteria	P	Ion transport protein	kcsA	GO:0003674,GO:0005215,GO:0005216,GO:0005244,GO:0005249,GO:0005261,GO:0005267,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022832,GO:0022836,GO:0022838,GO:0022839,GO:0022843,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2
TLS3_k127_49213_4	1120948.KB903217_gene1200	2.373e-157	507.0	COG2008@1|root,COG2008@2|Bacteria,2GMNV@201174|Actinobacteria,4DZFR@85010|Pseudonocardiales	201174|Actinobacteria	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
TLS3_k127_49213_8	1120948.KB903227_gene4840	1.322e-74	252.0	COG0745@1|root,COG0745@2|Bacteria,2I2VM@201174|Actinobacteria,4E2UJ@85010|Pseudonocardiales	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
TLS3_k127_4922514_0	1120948.KB903243_gene2568	9.355e-85	295.0	COG3021@1|root,COG3021@2|Bacteria,2GKXC@201174|Actinobacteria,4DZ69@85010|Pseudonocardiales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_4922514_2	1120948.KB903243_gene2572	4.36e-58	218.0	COG0394@1|root,COG0394@2|Bacteria,2GMPR@201174|Actinobacteria,4E6UA@85010|Pseudonocardiales	201174|Actinobacteria	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
TLS3_k127_4922514_1	1120948.KB903243_gene2575	4.607e-63	220.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4E2Q8@85010|Pseudonocardiales	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
TLS3_k127_4928603_3	1120948.KB903243_gene2469	1.79e-40	162.0	COG1960@1|root,COG1960@2|Bacteria,2I5JQ@201174|Actinobacteria,4E1PG@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_4928603_2	35754.JNYJ01000003_gene6594	4.248e-47	177.0	COG1802@1|root,COG1802@2|Bacteria,2I8SM@201174|Actinobacteria,4DD6Y@85008|Micromonosporales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
TLS3_k127_4928603_0	330084.JNYZ01000038_gene4153	1.002e-112	382.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4DZ5U@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_4928603_1	405948.SACE_2823	3.096e-58	207.0	COG1414@1|root,COG1414@2|Bacteria,2I9CD@201174|Actinobacteria,4DZGH@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
TLS3_k127_4954156_6	479431.Namu_5243	8.87e-130	428.0	COG0476@1|root,COG0476@2|Bacteria,2HQ2F@201174|Actinobacteria	201174|Actinobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	moeY	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0061503,GO:0061504,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	-	-	-	-	-	-	-	-	-	Nitroreductase,ThiF
TLS3_k127_4954156_12	479431.Namu_5242	1.139e-47	196.0	2C4J7@1|root,33WAI@2|Bacteria,2HB21@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_4954156_1	1120948.KB903240_gene4104	6.287e-239	751.0	COG0246@1|root,COG0246@2|Bacteria,2GJ4F@201174|Actinobacteria,4DZNZ@85010|Pseudonocardiales	201174|Actinobacteria	G	Mannitol dehydrogenase	mtlK	-	1.1.1.67	ko:K00045	ko00051,map00051	-	R00868	RC00085	ko00000,ko00001,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
TLS3_k127_4954156_11	685727.REQ_01300	7.435e-51	186.0	2DMA2@1|root,32B92@2|Bacteria,2IMA7@201174|Actinobacteria,4G17H@85025|Nocardiaceae	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
TLS3_k127_4954156_0	1120948.KB903222_gene592	1.234e-251	781.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4DXAN@85010|Pseudonocardiales	201174|Actinobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
TLS3_k127_4954156_9	1120948.KB903222_gene593	3.118e-87	309.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4E2KR@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
TLS3_k127_4954156_7	1120948.KB903222_gene594	3.925e-129	426.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4DXJJ@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS3_k127_4954156_5	67257.JODR01000030_gene2431	2.984e-143	469.0	COG2272@1|root,COG2272@2|Bacteria,2GJCN@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	-	-	-	-	-	-	-	-	-	COesterase
TLS3_k127_4954156_10	65497.JODV01000014_gene3392	1.27e-70	244.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4DZVG@85010|Pseudonocardiales	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
TLS3_k127_4954156_8	1120948.KB903222_gene598	2.772e-126	412.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,4DXFN@85010|Pseudonocardiales	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
TLS3_k127_4954156_4	1120948.KB903222_gene599	6.28e-152	485.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4DXSW@85010|Pseudonocardiales	201174|Actinobacteria	D	involved in chromosome partitioning	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
TLS3_k127_4954156_3	2074.JNYD01000013_gene6818	3.057e-161	517.0	COG0477@1|root,COG2814@2|Bacteria,2GM2G@201174|Actinobacteria,4DYSB@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Uncharacterised MFS-type transporter YbfB	pcaK	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_4,Sugar_tr
TLS3_k127_4954156_13	2074.JNYD01000023_gene1273	1.79e-44	169.0	COG1309@1|root,COG1309@2|Bacteria,2GMDA@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_4954156_2	2074.JNYD01000023_gene1272	1.167e-192	612.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,4DX3J@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
TLS3_k127_4973701_0	1120948.KB903229_gene5109	2.49e-123	406.0	COG0392@1|root,COG0392@2|Bacteria,2HN6N@201174|Actinobacteria,4E5QS@85010|Pseudonocardiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2.4.1	-	-	LPG_synthase_TM
TLS3_k127_4988312_0	1120948.KB903219_gene690	5.444e-84	279.0	COG0754@1|root,COG0754@2|Bacteria,2GMQ5@201174|Actinobacteria,4DXNW@85010|Pseudonocardiales	201174|Actinobacteria	E	Glutathionylspermidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	GSP_synth
TLS3_k127_4988312_1	1120948.KB903219_gene692	6.131e-56	199.0	COG3766@1|root,COG3766@2|Bacteria,2IFF9@201174|Actinobacteria,4E3RE@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
TLS3_k127_4988312_2	1120948.KB903219_gene693	5.523e-44	168.0	COG1807@1|root,COG1807@2|Bacteria,2GKH9@201174|Actinobacteria,4DYSK@85010|Pseudonocardiales	201174|Actinobacteria	M	Mycobacterial cell wall arabinan synthesis protein	-	-	-	ko:K11386	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Arabino_trans_C,Arabinose_trans
TLS3_k127_5026869_8	675635.Psed_0291	6.547e-28	128.0	COG1595@1|root,COG1595@2|Bacteria,2HGII@201174|Actinobacteria,4E4BW@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_5026869_7	1120948.KB903223_gene247	5.097e-37	143.0	COG0346@1|root,COG0346@2|Bacteria,2IKRS@201174|Actinobacteria,4E6US@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_5026869_1	1120948.KB903223_gene248	4.396e-95	317.0	COG4221@1|root,COG4221@2|Bacteria,2I461@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_5026869_4	1120948.KB903223_gene250	2.047e-53	192.0	COG1610@1|root,COG1610@2|Bacteria,2IFFJ@201174|Actinobacteria,4E44H@85010|Pseudonocardiales	201174|Actinobacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
TLS3_k127_5026869_3	1120948.KB903223_gene186	4.233e-84	290.0	COG1028@1|root,COG1028@2|Bacteria,2I95F@201174|Actinobacteria,4E4QR@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K14633	ko01057,ko01130,map01057,map01130	-	R09309,R09310	RC02484	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
TLS3_k127_5026869_2	1120948.KB903223_gene251	1.069e-90	305.0	COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria,4E2N3@85010|Pseudonocardiales	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_5026869_9	446462.Amir_1729	2.088e-15	89.0	COG2501@1|root,COG2501@2|Bacteria,2GQG8@201174|Actinobacteria,4E6Y0@85010|Pseudonocardiales	201174|Actinobacteria	S	S4 domain	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
TLS3_k127_5026869_5	1120948.KB903223_gene253	2.672e-50	186.0	2DYQK@1|root,34APV@2|Bacteria,2GTT2@201174|Actinobacteria,4E6M8@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF742)	-	-	-	-	-	-	-	-	-	-	-	-	DUF742
TLS3_k127_5026869_0	1120948.KB903223_gene254	7.263e-171	544.0	COG0709@1|root,COG0709@2|Bacteria,2GNP4@201174|Actinobacteria,4DYK1@85010|Pseudonocardiales	201174|Actinobacteria	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
TLS3_k127_5026869_6	1120948.KB903223_gene255	1.041e-45	165.0	COG0859@1|root,COG0859@2|Bacteria,2GMWP@201174|Actinobacteria,4E1C2@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
TLS3_k127_502819_2	526225.Gobs_2537	3.034e-09	64.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4EVDF@85013|Frankiales	201174|Actinobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
TLS3_k127_502819_3	390989.JOEG01000021_gene2652	3.004e-08	65.0	COG0664@1|root,COG0664@2|Bacteria,2I7B7@201174|Actinobacteria,4DAN8@85008|Micromonosporales	201174|Actinobacteria	K	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
TLS3_k127_502819_0	1120948.KB903218_gene1885	8.971e-261	816.0	COG1960@1|root,COG1960@2|Bacteria,2GJHM@201174|Actinobacteria,4DY8C@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
TLS3_k127_502819_1	1120948.KB903218_gene1884	2.402e-174	561.0	COG0596@1|root,COG0596@2|Bacteria,2H4IZ@201174|Actinobacteria,4DYNZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
TLS3_k127_5033166_2	1120948.KB903217_gene1215	2.562e-88	294.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4DYYV@85010|Pseudonocardiales	201174|Actinobacteria	F	PFAM AIR synthase related protein	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016882,GO:0044424,GO:0044444,GO:0044464	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
TLS3_k127_5033166_1	1127134.NOCYR_0592	2.457e-244	766.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4FU3Z@85025|Nocardiaceae	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
TLS3_k127_5033166_0	1120948.KB903217_gene1213	5.364e-312	972.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DYN9@85010|Pseudonocardiales	201174|Actinobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9
TLS3_k127_5033166_3	1463934.JOCF01000009_gene4704	1.039e-76	263.0	COG2890@1|root,COG2890@2|Bacteria,2GITA@201174|Actinobacteria	201174|Actinobacteria	J	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
TLS3_k127_5036582_1	2074.JNYD01000035_gene6749	7.09e-93	317.0	COG2353@1|root,COG2353@2|Bacteria,2GJFT@201174|Actinobacteria,4E2Y9@85010|Pseudonocardiales	201174|Actinobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,YceI
TLS3_k127_5036582_5	1120948.KB903243_gene2319	1.72e-20	99.0	2DSSU@1|root,33HAR@2|Bacteria,2GWP2@201174|Actinobacteria,4E7H7@85010|Pseudonocardiales	201174|Actinobacteria	S	Acyl-CoA carboxylase epsilon subunit	-	-	-	-	-	-	-	-	-	-	-	-	ACC_epsilon
TLS3_k127_5036582_0	1120948.KB903243_gene2318	4.4e-323	993.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4DZVN@85010|Pseudonocardiales	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	GO:0003674,GO:0003824,GO:0003989,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009317,GO:0009987,GO:0015977,GO:0016020,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0030312,GO:0032787,GO:0032991,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:1901575,GO:1902494	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
TLS3_k127_5036582_2	1120948.KB903243_gene2317	1.82e-86	294.0	COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,4E356@85010|Pseudonocardiales	201174|Actinobacteria	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
TLS3_k127_5036582_3	1120948.KB903243_gene2316	3.19e-40	163.0	COG3428@1|root,COG3428@2|Bacteria,2GK6Y@201174|Actinobacteria,4E2TI@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Bacterial membrane flanked domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
TLS3_k127_5036582_4	2074.JNYD01000012_gene446	3.716e-40	151.0	COG2030@1|root,COG2030@2|Bacteria,2HFAT@201174|Actinobacteria,4E46R@85010|Pseudonocardiales	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
TLS3_k127_5037450_5	675635.Psed_2298	5.52e-20	100.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4E2RP@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_5037450_4	1120948.KB903223_gene203	8.046e-63	230.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_5037450_1	1125971.ASJB01000031_gene1261	7.45e-121	429.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,4E2VY@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
TLS3_k127_5037450_3	675635.Psed_0714	4.318e-74	261.0	COG0778@1|root,COG0778@2|Bacteria,2I8P3@201174|Actinobacteria,4DYU0@85010|Pseudonocardiales	201174|Actinobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
TLS3_k127_5037450_0	1120948.KB903223_gene207	7.253e-194	643.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,4E0TS@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	devS	-	2.7.13.3	ko:K07682	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA_3
TLS3_k127_5037450_2	1120948.KB903223_gene206	8.942e-109	383.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,4E0TS@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
TLS3_k127_5037450_6	1122611.KB904007_gene7932	6.289e-18	93.0	2E3P4@1|root,32YM7@2|Bacteria,2HNF6@201174|Actinobacteria,4EKT9@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5037450_7	330084.JNYZ01000017_gene5225	6.486e-05	53.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4DZRD@85010|Pseudonocardiales	201174|Actinobacteria	C	Cytochrome bd-type quinol oxidase, subunit 1	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
TLS3_k127_5037923_3	1120948.KB903243_gene2524	4.319e-88	293.0	COG1028@1|root,COG1028@2|Bacteria,2GMWG@201174|Actinobacteria,4E2QJ@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	fabG	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_5037923_1	1120948.KB903243_gene2523	3.296e-139	457.0	COG0657@1|root,COG0657@2|Bacteria,2GJYR@201174|Actinobacteria,4EEQM@85010|Pseudonocardiales	201174|Actinobacteria	I	Carboxylesterase family	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
TLS3_k127_5037923_4	1120948.KB903243_gene2522	1.206e-84	292.0	COG2119@1|root,COG2119@2|Bacteria,2GNR0@201174|Actinobacteria,4E1CT@85010|Pseudonocardiales	201174|Actinobacteria	O	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
TLS3_k127_5037923_5	446470.Snas_6224	2.458e-52	208.0	COG0741@1|root,COG0741@2|Bacteria,2I2XS@201174|Actinobacteria,4EYPM@85014|Glycomycetales	201174|Actinobacteria	M	Membrane-bound lytic murein transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SLT_2
TLS3_k127_5037923_6	649831.L083_6333	6.34e-39	156.0	COG3861@1|root,COG3861@2|Bacteria,2IKWD@201174|Actinobacteria,4DKKR@85008|Micromonosporales	201174|Actinobacteria	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
TLS3_k127_5037923_2	1120948.KB903243_gene2519	3.715e-96	343.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4DX58@85010|Pseudonocardiales	201174|Actinobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
TLS3_k127_5037923_0	1120948.KB903243_gene2518	1.086e-163	529.0	COG3320@1|root,COG3320@2|Bacteria,2GKZY@201174|Actinobacteria,4E2RN@85010|Pseudonocardiales	201174|Actinobacteria	Q	Male sterility protein	acrA1_1	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
TLS3_k127_5037923_7	1120948.KB903243_gene2517	3.787e-27	112.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4DXY1@85010|Pseudonocardiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_5046811_0	1120948.KB903243_gene2640	7.725e-206	653.0	COG0001@1|root,COG0001@2|Bacteria,2GKJV@201174|Actinobacteria,4DYF7@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,Methyltransf_13,Methyltransf_14
TLS3_k127_5046811_1	1380356.JNIK01000004_gene169	8.052e-56	220.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,4ERZS@85013|Frankiales	201174|Actinobacteria	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
TLS3_k127_5048861_0	1206741.BAFX01000183_gene7621	1.589e-96	340.0	COG0438@1|root,COG0438@2|Bacteria,2HFN4@201174|Actinobacteria,4G7AY@85025|Nocardiaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_5048861_2	1157943.KB892705_gene489	8.593e-82	302.0	COG0438@1|root,COG0438@2|Bacteria,2IDYW@201174|Actinobacteria,236IE@1762|Mycobacteriaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_5048861_1	1206741.BAFX01000183_gene7619	1.309e-92	324.0	COG3307@1|root,COG3307@2|Bacteria,2H0EI@201174|Actinobacteria	201174|Actinobacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
TLS3_k127_5056003_2	1120948.KB903240_gene3752	4.075e-116	381.0	COG0584@1|root,COG0584@2|Bacteria,2GJ5W@201174|Actinobacteria,4DZWJ@85010|Pseudonocardiales	201174|Actinobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ2	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
TLS3_k127_5056003_4	1120948.KB903240_gene3753	4.517e-61	215.0	2CNY9@1|root,31DSU@2|Bacteria,2I80U@201174|Actinobacteria,4E3N8@85010|Pseudonocardiales	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	RbpA
TLS3_k127_5056003_3	1120934.KB894404_gene720	2.149e-75	286.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria,4DYYD@85010|Pseudonocardiales	201174|Actinobacteria	S	Glycosyltransferase like family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
TLS3_k127_5056003_0	1120948.KB903240_gene3755	4.265e-214	685.0	COG0815@1|root,COG0815@2|Bacteria,2GJ9F@201174|Actinobacteria,4DXYD@85010|Pseudonocardiales	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	GO:0000030,GO:0003674,GO:0003824,GO:0004582,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070085,GO:0071704,GO:0071944,GO:0075136,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	iNJ661.Rv2051c	CN_hydrolase
TLS3_k127_5056003_1	1120948.KB903240_gene3756	2.209e-119	386.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4DXYB@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the peptidase M24B family	pepE	-	3.4.13.9	ko:K01271,ko:K01274	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
TLS3_k127_506180_1	66429.JOFL01000020_gene5564	1.338e-49	181.0	COG3305@1|root,COG3305@2|Bacteria,2GNU5@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2127
TLS3_k127_506180_0	258052.JNYV01000003_gene4928	5.987e-69	246.0	COG1295@1|root,COG1295@2|Bacteria,2ICUY@201174|Actinobacteria	201174|Actinobacteria	I	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
TLS3_k127_506348_1	405948.SACE_1349	1.507e-52	187.0	COG0698@1|root,COG0698@2|Bacteria,2GKJG@201174|Actinobacteria,4E2S1@85010|Pseudonocardiales	201174|Actinobacteria	G	Ribose 5-phosphate isomerase	rpiB	GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005576,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2465c	LacAB_rpiB
TLS3_k127_506348_0	1123023.JIAI01000012_gene9075	4.158e-112	367.0	COG0266@1|root,COG0266@2|Bacteria,2GKUI@201174|Actinobacteria,4E0QZ@85010|Pseudonocardiales	201174|Actinobacteria	L	Belongs to the FPG family	nei1	GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0003906,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0090304,GO:0097159,GO:0097506,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K05522,ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
TLS3_k127_5073258_6	479431.Namu_4245	2.615e-13	80.0	COG2314@1|root,COG2314@2|Bacteria,2GSEK@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707
TLS3_k127_5073258_2	931627.MycrhDRAFT_0843	5.165e-87	302.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,2366U@1762|Mycobacteriaceae	201174|Actinobacteria	S	membrane	pcl	-	-	-	-	-	-	-	-	-	-	-	VIT1
TLS3_k127_5073258_0	1120948.KB903243_gene2512	8.739e-129	420.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria,4E1PX@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
TLS3_k127_5073258_4	395495.Lcho_1122	5.673e-45	175.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2VN7W@28216|Betaproteobacteria,1KIZJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
TLS3_k127_5073258_1	103733.JNYO01000003_gene8225	2.781e-115	383.0	COG1073@1|root,COG1073@2|Bacteria,2GJE5@201174|Actinobacteria,4DZUS@85010|Pseudonocardiales	201174|Actinobacteria	S	Secretory lipase	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	LIP
TLS3_k127_5073258_3	1120948.KB903243_gene2514	4.162e-59	206.0	COG2197@1|root,COG2197@2|Bacteria,2GN46@201174|Actinobacteria,4DXJI@85010|Pseudonocardiales	201174|Actinobacteria	K	Response regulator receiver domain	bldM	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_5093328_2	1120948.KB903217_gene1335	5.688e-36	137.0	COG1960@1|root,COG1960@2|Bacteria,2GVSU@201174|Actinobacteria,4DYFB@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_5093328_1	1246445.ANAY01000002_gene3514	1.571e-64	234.0	28HG7@1|root,2Z7S3@2|Bacteria,2GMJK@201174|Actinobacteria,4EIKX@85012|Streptosporangiales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N,Wyosine_form
TLS3_k127_5093328_0	1429046.RR21198_5875	5.211e-181	587.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4FV31@85025|Nocardiaceae	201174|Actinobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
TLS3_k127_5117866_0	1120948.KB903221_gene417	7.269e-59	216.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,2GKEU@201174|Actinobacteria,4E2GT@85010|Pseudonocardiales	201174|Actinobacteria	V	Forkhead associated domain	-	-	-	ko:K01990,ko:K21397	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA
TLS3_k127_5117866_1	1123023.JIAI01000003_gene3121	3.437e-30	139.0	COG0515@1|root,COG0515@2|Bacteria,2HN7A@201174|Actinobacteria,4DYIY@85010|Pseudonocardiales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF3558,Pkinase
TLS3_k127_5157236_3	1120948.KB903229_gene5270	7.25e-56	205.0	COG4572@1|root,COG4572@2|Bacteria,2IMHQ@201174|Actinobacteria,4E4T3@85010|Pseudonocardiales	201174|Actinobacteria	S	ChaB	chaB	-	-	-	-	-	-	-	-	-	-	-	ChaB,Rho_N
TLS3_k127_5157236_0	1120948.KB903229_gene5269	4.761e-138	454.0	COG0647@1|root,COG0647@2|Bacteria,2GJG6@201174|Actinobacteria,4DY2U@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the HAD-like hydrolase superfamily	nagD	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
TLS3_k127_5157236_2	1120948.KB903229_gene5268	3.093e-102	338.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4DZTQ@85010|Pseudonocardiales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
TLS3_k127_5157236_4	2074.JNYD01000016_gene4145	2.114e-48	177.0	COG1764@1|root,COG1764@2|Bacteria,2IID0@201174|Actinobacteria,4E3PB@85010|Pseudonocardiales	201174|Actinobacteria	O	OsmC-like protein	ohr	-	-	-	-	-	-	-	-	-	-	-	OsmC
TLS3_k127_5157236_1	1120948.KB903229_gene5266	6.408e-123	408.0	COG0657@1|root,COG0657@2|Bacteria,2GJYR@201174|Actinobacteria,4E9IF@85010|Pseudonocardiales	201174|Actinobacteria	I	Carboxylesterase family	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
TLS3_k127_5165159_2	1120948.KB903217_gene944	1.274e-44	163.0	COG2303@1|root,COG2303@2|Bacteria,2GJ3J@201174|Actinobacteria,4DYHW@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the oxidation and isomerization of cholesterol to cholestenone (4-cholesten-3-one), which is an initial step in the cholesterol degradation process. Required for virulence	choD	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_binding_2,GMC_oxred_C,GMC_oxred_N
TLS3_k127_5165159_1	1120948.KB903217_gene945	2.244e-85	290.0	COG3340@1|root,COG3340@2|Bacteria,2GN35@201174|Actinobacteria,4E2VT@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the peptidase S51 family	pepE	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
TLS3_k127_5165159_0	1120948.KB903217_gene947	2.065e-215	697.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria,4DY70@85010|Pseudonocardiales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
TLS3_k127_5165356_0	1123023.JIAI01000020_gene2082	4.16e-221	698.0	COG0072@1|root,COG0072@2|Bacteria,2GMFD@201174|Actinobacteria,4DYCC@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
TLS3_k127_5169286_0	1120948.KB903217_gene1209	0.0	1046.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4DXHH@85010|Pseudonocardiales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
TLS3_k127_5174906_3	1120948.KB903244_gene3109	3.167e-86	296.0	COG5640@1|root,COG5640@2|Bacteria,2GN18@201174|Actinobacteria,4DZTJ@85010|Pseudonocardiales	201174|Actinobacteria	O	Secreted trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
TLS3_k127_5174906_0	1120948.KB903244_gene3110	2.439e-217	684.0	COG1249@1|root,COG1249@2|Bacteria,2GNSR@201174|Actinobacteria,4DZ6N@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	mtr	-	1.8.1.15	ko:K17883	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_5174906_2	882083.SacmaDRAFT_5231	1.779e-98	332.0	COG0842@1|root,COG0842@2|Bacteria,2GJGH@201174|Actinobacteria,4E037@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
TLS3_k127_5174906_1	469383.Cwoe_4032	9.993e-133	431.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
TLS3_k127_5174906_5	1380393.JHVP01000018_gene132	2.067e-45	171.0	COG1309@1|root,COG1309@2|Bacteria,2HAGC@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K18476	-	M00668	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C,TetR_N
TLS3_k127_5174906_4	1120948.KB903244_gene3113	1.062e-68	251.0	COG1309@1|root,COG1309@2|Bacteria,2GMCG@201174|Actinobacteria,4E2RD@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_5174906_6	1120948.KB903244_gene3114	6.287e-36	149.0	2BVHN@1|root,32QW3@2|Bacteria,2IKWS@201174|Actinobacteria,4E3RM@85010|Pseudonocardiales	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
TLS3_k127_5182860_1	1120948.KB903244_gene2751	2.231e-40	161.0	COG1335@1|root,COG1335@2|Bacteria,2GPXN@201174|Actinobacteria,4EEW7@85010|Pseudonocardiales	201174|Actinobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
TLS3_k127_5182860_0	675635.Psed_6293	1.435e-204	642.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4E9VP@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	caiA	-	1.3.8.13	ko:K08297,ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_5186074_4	1415166.NONO_c43980	1.802e-126	408.0	COG1028@1|root,COG1028@2|Bacteria,2GNM4@201174|Actinobacteria,4G8QX@85025|Nocardiaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_5186074_6	1003195.SCAT_4014	1.708e-67	239.0	COG0697@1|root,COG0697@2|Bacteria,2I198@201174|Actinobacteria	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_5186074_0	1120948.KB903218_gene1836	1.238e-302	936.0	COG2072@1|root,COG2072@2|Bacteria,2GK95@201174|Actinobacteria,4DYPV@85010|Pseudonocardiales	201174|Actinobacteria	P	Flavin-binding monooxygenase-like	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	FMO-like,Pyr_redox_3
TLS3_k127_5186074_2	1120948.KB903218_gene1835	4.8e-211	671.0	COG0477@1|root,COG0477@2|Bacteria,2IBIG@201174|Actinobacteria,4DYA6@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_5186074_3	1120948.KB903218_gene1837	1.686e-167	565.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DZXZ@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
TLS3_k127_5186074_11	1445613.JALM01000100_gene6224	8.617e-08	57.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZWD@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_5186074_9	287986.DV20_42890	4.216e-18	87.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZWD@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_5186074_10	1068978.AMETH_4001	1.013e-16	83.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZWD@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_5186074_8	2074.JNYD01000021_gene829	4.809e-35	141.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZWD@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_5186074_5	675635.Psed_3898	6.658e-117	391.0	COG1028@1|root,COG1028@2|Bacteria,2I48H@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_5186074_7	2074.JNYD01000003_gene3951	2.796e-51	185.0	COG0454@1|root,COG0456@2|Bacteria,2GVA0@201174|Actinobacteria,4EBXK@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_5186074_1	675635.Psed_1490	1.297e-226	717.0	COG1024@1|root,COG1024@2|Bacteria,2GMNR@201174|Actinobacteria,4E08J@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	boxC	-	4.1.2.44	ko:K15513	ko00362,map00362	-	R09556	RC03426	ko00000,ko00001,ko01000	-	-	-	ECH_1
TLS3_k127_5198599_13	1120948.KB903229_gene5318	1.006e-22	99.0	COG2130@1|root,COG2130@2|Bacteria,2GKR8@201174|Actinobacteria,4DXUY@85010|Pseudonocardiales	201174|Actinobacteria	S	NADP-dependent oxidoreductase	yfmJ	-	1.6.5.5	ko:K00344,ko:K07119	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N_2,ADH_zinc_N
TLS3_k127_5198599_1	526225.Gobs_2062	0.0	1113.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4EX4J@85013|Frankiales	201174|Actinobacteria	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
TLS3_k127_5198599_9	1120948.KB903243_gene2307	4.562e-61	221.0	COG4758@1|root,COG4758@2|Bacteria,2I8FE@201174|Actinobacteria,4E31D@85010|Pseudonocardiales	201174|Actinobacteria	S	Cell wall-active antibiotics response 4TMS YvqF	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
TLS3_k127_5198599_4	1120948.KB903229_gene5315	1.852e-170	562.0	COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4E01U@85010|Pseudonocardiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_5198599_5	1120948.KB903229_gene5314	7.899e-138	441.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4DY4M@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	tcrX	GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0098771	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_5198599_16	1236902.ANAS01000004_gene3534	1.171e-14	79.0	COG3540@1|root,COG3540@2|Bacteria,2GJCI@201174|Actinobacteria,4EFNV@85012|Streptosporangiales	201174|Actinobacteria	P	PhoD-like phosphatase, N-terminal domain	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
TLS3_k127_5198599_7	1120948.KB903229_gene5068	9.233e-74	259.0	COG0702@1|root,COG0702@2|Bacteria,2I234@201174|Actinobacteria,4E63K@85010|Pseudonocardiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
TLS3_k127_5198599_15	1380347.JNII01000005_gene3423	1.791e-16	84.0	2CC94@1|root,2ZI02@2|Bacteria,2HCEG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5198599_6	479432.Sros_4195	5.248e-77	268.0	COG3832@1|root,COG3832@2|Bacteria,2IE7C@201174|Actinobacteria,4EJ4Q@85012|Streptosporangiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_5198599_3	1120948.KB903229_gene5309	4.005e-174	550.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4DYP5@85010|Pseudonocardiales	201174|Actinobacteria	E	LAO AO transport system ATPase	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
TLS3_k127_5198599_12	1123024.AUII01000001_gene3028	2.778e-29	126.0	COG3744@1|root,COG3744@2|Bacteria,2GSS6@201174|Actinobacteria	201174|Actinobacteria	S	PilT protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN
TLS3_k127_5198599_14	1123024.AUII01000001_gene3027	2.65e-20	93.0	COG4118@1|root,COG4118@2|Bacteria,2IQGB@201174|Actinobacteria	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
TLS3_k127_5198599_0	1120948.KB903229_gene5307	0.0	1277.0	COG2185@1|root,COG2185@2|Bacteria,2I2N3@201174|Actinobacteria,4EF65@85010|Pseudonocardiales	201174|Actinobacteria	I	B12 binding domain	mutB	GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016999,GO:0017144,GO:0019541,GO:0019678,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044464,GO:0046459,GO:0071704,GO:0071944	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
TLS3_k127_5198599_2	1068980.ARVW01000001_gene2278	2.584e-177	590.0	COG1884@1|root,COG1884@2|Bacteria,2GNBQ@201174|Actinobacteria,4DYG1@85010|Pseudonocardiales	201174|Actinobacteria	I	Methylmalonyl-CoA mutase	mutA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016999,GO:0017144,GO:0019541,GO:0019678,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046459,GO:0071704,GO:0071944	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
TLS3_k127_5198599_10	1122182.KB903825_gene249	2.675e-52	194.0	COG1396@1|root,COG1396@2|Bacteria,2GPWH@201174|Actinobacteria,4D8N2@85008|Micromonosporales	201174|Actinobacteria	K	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
TLS3_k127_5198599_8	1206739.BAGJ01000037_gene2718	9.931e-68	242.0	COG0492@1|root,COG0492@2|Bacteria,2GIXN@201174|Actinobacteria,4FYCP@85025|Nocardiaceae	201174|Actinobacteria	O	pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
TLS3_k127_5212460_1	1120948.KB903246_gene3399	3.106e-195	614.0	COG2837@1|root,COG2837@2|Bacteria,2GIUB@201174|Actinobacteria,4DXQP@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM Dyp-type peroxidase	efeN	-	-	ko:K16301	-	-	-	-	ko00000,ko01000,ko02000	2.A.108.2.3	-	-	Dyp_perox
TLS3_k127_5212460_2	1120948.KB903246_gene3398	8.495e-105	351.0	COG2951@1|root,COG2951@2|Bacteria,2GX49@201174|Actinobacteria,4E173@85010|Pseudonocardiales	201174|Actinobacteria	M	Membrane-bound lytic murein transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	SLT_2
TLS3_k127_5212460_3	1120948.KB903246_gene3397	9.174e-51	186.0	COG0457@1|root,COG0457@2|Bacteria,2I3MN@201174|Actinobacteria,4E4BA@85010|Pseudonocardiales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
TLS3_k127_5212460_0	1120948.KB903246_gene3396	4.041e-248	773.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4DXDR@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
TLS3_k127_5212460_4	1120948.KB903246_gene3395	2.437e-32	135.0	COG2919@1|root,COG2919@2|Bacteria,2GQH7@201174|Actinobacteria,4E5EA@85010|Pseudonocardiales	201174|Actinobacteria	D	Septum formation initiator	divIC	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
TLS3_k127_5214571_0	1120948.KB903219_gene649	7.924e-224	701.0	COG1457@1|root,COG1457@2|Bacteria,2I0NE@201174|Actinobacteria,4E273@85010|Pseudonocardiales	201174|Actinobacteria	F	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
TLS3_k127_5214571_1	1123024.AUII01000006_gene4596	5.89e-150	489.0	COG2755@1|root,COG2755@2|Bacteria,2HWFS@201174|Actinobacteria	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS3_k127_5214571_2	1120948.KB903219_gene650	8.554e-71	242.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4E1EE@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Alcohol dehydrogenase GroES-like domain	fdhA	-	1.2.1.46	ko:K00148	ko00625,ko00680,ko01100,ko01120,ko01200,map00625,map00680,map01100,map01120,map01200	-	R00604	RC00188	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
TLS3_k127_5215646_2	405948.SACE_1304	1.877e-53	194.0	COG1670@1|root,COG1670@2|Bacteria,2H866@201174|Actinobacteria,4E4QF@85010|Pseudonocardiales	201174|Actinobacteria	J	Siderophore biosynthesis protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_8
TLS3_k127_5215646_1	1120948.KB903243_gene2508	1.927e-77	263.0	COG1443@1|root,COG1443@2|Bacteria,2GM26@201174|Actinobacteria,4E32X@85010|Pseudonocardiales	201174|Actinobacteria	I	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)	idi	GO:0003674,GO:0003824,GO:0004452,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046490,GO:0071704,GO:0090407,GO:1901576	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1745c	NUDIX
TLS3_k127_5215646_0	1133849.O3I_007615	2.251e-90	304.0	COG4319@1|root,COG4319@2|Bacteria,2II1S@201174|Actinobacteria,4G18S@85025|Nocardiaceae	201174|Actinobacteria	E	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
TLS3_k127_5216729_1	1137271.AZUM01000002_gene2832	1.867e-07	63.0	COG4977@1|root,COG4977@2|Bacteria,2I2KX@201174|Actinobacteria,4E4P6@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
TLS3_k127_5216729_0	1123024.AUII01000007_gene4822	2.035e-86	292.0	COG2060@1|root,COG2060@2|Bacteria,2GK51@201174|Actinobacteria,4DXMS@85010|Pseudonocardiales	201174|Actinobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
TLS3_k127_5219845_8	1394178.AWOO02000069_gene296	2.656e-66	231.0	COG0604@1|root,COG0604@2|Bacteria,2GMA2@201174|Actinobacteria,4EISC@85012|Streptosporangiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
TLS3_k127_5219845_3	287986.DV20_29795	7.27e-148	473.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria,4E29Q@85010|Pseudonocardiales	201174|Actinobacteria	Q	Catechol dioxygenase N terminus	-	-	1.13.11.1,1.13.11.37	ko:K03381,ko:K04098	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R03891,R04061,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01016,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
TLS3_k127_5219845_4	1380393.JHVP01000003_gene922	1.19e-143	458.0	COG0372@1|root,COG0372@2|Bacteria,2H9YP@201174|Actinobacteria,4ESVG@85013|Frankiales	201174|Actinobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
TLS3_k127_5219845_2	1122611.KB903985_gene3715	2.999e-197	622.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4EHCR@85012|Streptosporangiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
TLS3_k127_5219845_5	1120948.KB903243_gene2412	6.04e-137	441.0	COG1414@1|root,COG1414@2|Bacteria,2GNHA@201174|Actinobacteria,4DZJ6@85010|Pseudonocardiales	201174|Actinobacteria	K	TIGRFAM beta-ketoadipate pathway transcriptional regulators, PcaR PcaU PobR family	-	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
TLS3_k127_5219845_0	1120948.KB903243_gene2413	3.231e-257	799.0	COG0402@1|root,COG0402@2|Bacteria,2GNUN@201174|Actinobacteria,4E02S@85010|Pseudonocardiales	201174|Actinobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
TLS3_k127_5219845_6	1120948.KB903243_gene2411	5.344e-123	414.0	COG0654@1|root,COG0654@2|Bacteria,2GM48@201174|Actinobacteria,4DY2I@85010|Pseudonocardiales	201174|Actinobacteria	CH	4-hydroxybenzoate 3-monooxygenase	-	-	1.14.13.2	ko:K00481	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R01298	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
TLS3_k127_5219845_10	68170.KL590493_gene6389	5.999e-28	128.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4E3IX@85010|Pseudonocardiales	201174|Actinobacteria	V	Domain of unknown function (DUF222)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
TLS3_k127_5219845_7	101510.RHA1_ro00742	1.704e-79	269.0	COG0346@1|root,COG0346@2|Bacteria,2IFKS@201174|Actinobacteria,4G0G1@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
TLS3_k127_5219845_1	1120948.KB903246_gene3237	1.055e-241	762.0	COG2072@1|root,COG2072@2|Bacteria,2GM3S@201174|Actinobacteria,4E08C@85010|Pseudonocardiales	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
TLS3_k127_5219845_9	1120948.KB903229_gene5145	7.958e-56	198.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria,4E0Y5@85010|Pseudonocardiales	201174|Actinobacteria	I	Fatty acid desaturase	desA3	GO:0001676,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016053,GO:0016213,GO:0016215,GO:0016491,GO:0016705,GO:0016717,GO:0019752,GO:0032787,GO:0042759,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:0072330,GO:1901576	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_5224553_0	1120948.KB903217_gene1384	1.158e-170	541.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4DX7I@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway	mshA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_5224553_2	1120948.KB903217_gene1383	4.923e-122	396.0	COG4221@1|root,COG4221@2|Bacteria,2GMGQ@201174|Actinobacteria,4DYP8@85010|Pseudonocardiales	201174|Actinobacteria	S	Short-chain alcohol dehydrogenase	sdh	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.381	ko:K16066	ko00240,ko00260,ko01100,map00240,map00260,map01100	-	R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000	-	-	-	adh_short
TLS3_k127_5224553_1	675635.Psed_0597	6.663e-126	407.0	COG1376@1|root,COG1376@2|Bacteria,2GJBA@201174|Actinobacteria,4DZ3S@85010|Pseudonocardiales	201174|Actinobacteria	S	L,D-transpeptidase catalytic domain	lprQ	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	YkuD
TLS3_k127_5229127_9	349521.HCH_06817	2.951e-12	72.0	COG0524@1|root,COG0524@2|Bacteria,1QTMT@1224|Proteobacteria,1S1JQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
TLS3_k127_5229127_5	65497.JODV01000009_gene2818	8.73e-70	258.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4DXNB@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
TLS3_k127_5229127_10	1169161.KB897719_gene3481	0.0001499	45.0	COG3290@1|root,COG3850@1|root,COG3290@2|Bacteria,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA_3,PAS_4
TLS3_k127_5229127_4	1120948.KB903223_gene212	7.346e-97	337.0	COG4585@1|root,COG5278@1|root,COG4585@2|Bacteria,COG5278@2|Bacteria,2I8IA@201174|Actinobacteria,4EC0W@85010|Pseudonocardiales	201174|Actinobacteria	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HisKA_3
TLS3_k127_5229127_6	640132.Srot_0389	7.224e-27	120.0	291ZT@1|root,2ZPJ4@2|Bacteria,2GR7R@201174|Actinobacteria	201174|Actinobacteria	S	regulation of cellular protein catabolic process	bpa	GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369	-	-	-	-	-	-	-	-	-	-	DUF2587
TLS3_k127_5229127_8	405948.SACE_2404	2.705e-12	81.0	COG0236@1|root,COG0236@2|Bacteria,2GRZ8@201174|Actinobacteria,4E7Z1@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
TLS3_k127_5229127_3	405948.SACE_2405	4.694e-130	428.0	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria,4E8QP@85010|Pseudonocardiales	201174|Actinobacteria	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS3_k127_5229127_1	1957.JODX01000030_gene6042	9.618e-148	493.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
TLS3_k127_5229127_2	1206732.BAGD01000277_gene6276	2.102e-144	474.0	COG1071@1|root,COG1071@2|Bacteria,2IBRC@201174|Actinobacteria,4FUP9@85025|Nocardiaceae	201174|Actinobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
TLS3_k127_5229127_0	1089544.KB912942_gene2768	4.157e-258	811.0	COG0365@1|root,COG0365@2|Bacteria,2GNE8@201174|Actinobacteria,4E1U5@85010|Pseudonocardiales	201174|Actinobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_5229127_7	1123023.JIAI01000030_gene4390	2.885e-24	103.0	COG0071@1|root,COG0071@2|Bacteria,2GQGQ@201174|Actinobacteria,4E6NB@85010|Pseudonocardiales	201174|Actinobacteria	O	Hsp20/alpha crystallin family	hspX	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
TLS3_k127_5277586_0	1120948.KB903229_gene5365	6.167e-183	575.0	COG0433@1|root,COG0433@2|Bacteria,2GM12@201174|Actinobacteria,4DXWC@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
TLS3_k127_5277586_1	1120948.KB903229_gene5362	2.244e-65	226.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4E178@85010|Pseudonocardiales	201174|Actinobacteria	V	MacB-like periplasmic core domain	yknZ	-	-	ko:K02004,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	FtsX,MacB_PCD
TLS3_k127_5285928_1	1210046.B277_07810	1.299e-107	357.0	COG2610@1|root,COG2610@2|Bacteria,2GITQ@201174|Actinobacteria,4FG23@85021|Intrasporangiaceae	201174|Actinobacteria	EG	GntP family permease	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
TLS3_k127_5285928_3	479433.Caci_0872	1.081e-36	150.0	COG1309@1|root,COG1309@2|Bacteria,2I9IJ@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
TLS3_k127_5285928_2	1123024.AUII01000011_gene4454	1.042e-64	232.0	COG4583@1|root,COG4583@2|Bacteria,2IFA6@201174|Actinobacteria	201174|Actinobacteria	E	Sarcosine oxidase, gamma subunit family	-	-	1.5.3.1	ko:K00305	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2,SoxG
TLS3_k127_5285928_0	1123024.AUII01000011_gene4455	0.0	1412.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,2GMBK@201174|Actinobacteria,4E081@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the GcvT family	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
TLS3_k127_5285928_4	1123024.AUII01000011_gene4456	1.747e-08	56.0	COG4311@1|root,COG4311@2|Bacteria,2GVD9@201174|Actinobacteria	201174|Actinobacteria	E	Sarcosine oxidase, delta subunit family	-	-	1.5.3.1	ko:K00304	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxD
TLS3_k127_5293434_1	1120948.KB903219_gene647	1.038e-117	380.0	COG0745@1|root,COG0745@2|Bacteria,2H5RN@201174|Actinobacteria,4EBFS@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_5293434_0	1120948.KB903219_gene694	2.543e-173	557.0	COG4346@1|root,COG4346@2|Bacteria,2GJXE@201174|Actinobacteria,4DX7T@85010|Pseudonocardiales	201174|Actinobacteria	O	Dolichyl-phosphate-mannose--protein O-mannosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5298134_0	1120948.KB903217_gene947	5.597e-256	799.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria,4DY70@85010|Pseudonocardiales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
TLS3_k127_5298134_2	1120948.KB903217_gene948	3.089e-41	168.0	2BQBU@1|root,32J6Y@2|Bacteria,2GXAW@201174|Actinobacteria,4ED86@85010|Pseudonocardiales	201174|Actinobacteria	S	Family of unknown function (DUF5313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5313
TLS3_k127_5298134_1	1120948.KB903217_gene954	8.285e-137	448.0	COG1807@1|root,COG1807@2|Bacteria,2GK3Q@201174|Actinobacteria,4DZ07@85010|Pseudonocardiales	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_5309219_0	1120948.KB903229_gene5340	4.734e-98	325.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4DXY1@85010|Pseudonocardiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_5309219_3	2002.JOEQ01000002_gene4544	6.108e-10	70.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4EGP6@85012|Streptosporangiales	201174|Actinobacteria	O	Clp amino terminal domain, pathogenicity island component	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,Clp_N,Peptidase_C14,TIR_2
TLS3_k127_5309219_1	35754.JNYJ01000036_gene3612	3.53e-53	191.0	COG1247@1|root,COG1247@2|Bacteria,2ISV7@201174|Actinobacteria,4DFXW@85008|Micromonosporales	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_5309219_2	1123023.JIAI01000011_gene8825	7.267e-43	158.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4DZY6@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the peptidase M48B family	htpX	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
TLS3_k127_5312766_0	1120948.KB903231_gene4710	1.184e-217	691.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4DX7X@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	pdtaS	GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2,PAS_4
TLS3_k127_5312766_6	1120948.KB903231_gene4711	2.091e-52	192.0	COG5662@1|root,COG5662@2|Bacteria,2IM2X@201174|Actinobacteria,4E6KJ@85010|Pseudonocardiales	201174|Actinobacteria	K	anti-sigma factor	rsrA	GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	-	-	-	-	-	-	-	-	-	-	zf-HC2
TLS3_k127_5312766_3	1120948.KB903231_gene4712	3.991e-101	338.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4DXKC@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_5312766_5	1120948.KB903231_gene4713	4.896e-59	211.0	COG2606@1|root,COG2606@2|Bacteria,2IHS8@201174|Actinobacteria,4E2M0@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
TLS3_k127_5312766_4	1120948.KB903231_gene4716	2.049e-83	302.0	COG3571@1|root,COG3571@2|Bacteria,2GKKE@201174|Actinobacteria,4E16F@85010|Pseudonocardiales	201174|Actinobacteria	S	Hydrolase of the alpha beta-hydrolase	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	DLH
TLS3_k127_5312766_2	1120948.KB903231_gene4717	1.943e-106	354.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,4E13E@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the SOS response-associated peptidase family	yedK	-	-	-	-	-	-	-	-	-	-	-	SRAP
TLS3_k127_5312766_1	1120948.KB903231_gene4718	2.191e-114	382.0	COG0128@1|root,COG0128@2|Bacteria,2GJKX@201174|Actinobacteria,4DZN4@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
TLS3_k127_5320239_4	479431.Namu_0254	6.939e-11	69.0	COG2755@1|root,COG2755@2|Bacteria,2GNBP@201174|Actinobacteria,4ESPP@85013|Frankiales	201174|Actinobacteria	E	PFAM lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS3_k127_5320239_2	2074.JNYD01000001_gene6173	1.119e-36	149.0	2FGAK@1|root,3486Y@2|Bacteria,2IQYK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5320239_0	479435.Kfla_1667	4.043e-127	435.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria,4DPZI@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
TLS3_k127_5320239_1	68199.JNZO01000027_gene6161	1.094e-68	251.0	COG1252@1|root,COG1252@2|Bacteria,2GKC0@201174|Actinobacteria	201174|Actinobacteria	C	pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
TLS3_k127_5320239_5	1068978.AMETH_5603	1.709e-10	68.0	COG1366@1|root,COG1366@2|Bacteria,2GVQ6@201174|Actinobacteria,4E731@85010|Pseudonocardiales	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
TLS3_k127_5320239_3	1120948.KB903240_gene3894	1.046e-12	68.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4DXR6@85010|Pseudonocardiales	201174|Actinobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
TLS3_k127_532210_0	1120948.KB903217_gene1033	3.222e-60	227.0	COG2259@1|root,COG2259@2|Bacteria,2HD6Y@201174|Actinobacteria,4E4RT@85010|Pseudonocardiales	201174|Actinobacteria	S	DoxX	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
TLS3_k127_532210_1	1120948.KB903217_gene1031	7.302e-28	116.0	COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria,4DX7H@85010|Pseudonocardiales	201174|Actinobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,TspO_MBR
TLS3_k127_5346218_2	1120948.KB903243_gene2631	7.66e-47	176.0	COG1131@1|root,COG1131@2|Bacteria,2HCMG@201174|Actinobacteria	201174|Actinobacteria	V	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5346218_1	1120948.KB903243_gene2632	9.189e-51	198.0	29AYA@1|root,2ZXXD@2|Bacteria,2HA6M@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5346218_0	1120948.KB903243_gene2633	7.416e-108	379.0	2FGEN@1|root,348AP@2|Bacteria,2GRWX@201174|Actinobacteria,4E7Z9@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_536644_3	164757.Mjls_1133	5.526e-21	106.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,2343K@1762|Mycobacteriaceae	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_536644_1	479431.Namu_2452	5.461e-37	145.0	COG1983@1|root,COG1983@2|Bacteria,2GWIA@201174|Actinobacteria	201174|Actinobacteria	KT	Phage shock protein C (PspC)	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
TLS3_k127_536644_5	1896.JOAU01000005_gene5067	0.0001392	53.0	COG1983@1|root,COG1983@2|Bacteria,2GIVS@201174|Actinobacteria	201174|Actinobacteria	KT	PspC domain protein	pspC	-	-	-	-	-	-	-	-	-	-	-	DUF2154,PspC
TLS3_k127_536644_0	1123024.AUII01000001_gene3105	0.0	1182.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,4E01Z@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 65, N-terminal domain	otsB1	GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0030312,GO:0044464,GO:0071944	3.1.3.12,3.2.1.28	ko:K01087,ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010,R02778	RC00017,RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Hydrolase,Trehalose_PPase
TLS3_k127_536644_4	1122611.KB904007_gene7932	2.061e-15	85.0	2E3P4@1|root,32YM7@2|Bacteria,2HNF6@201174|Actinobacteria,4EKT9@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_536644_2	1449976.KALB_3570	3.059e-31	127.0	COG0045@1|root,COG0454@1|root,COG1042@1|root,COG0045@2|Bacteria,COG0456@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4DZ1D@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
TLS3_k127_5372812_0	1120948.KB903244_gene3037	1.096e-303	937.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4DXB7@85010|Pseudonocardiales	201174|Actinobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
TLS3_k127_5372812_1	1120948.KB903244_gene3038	5.405e-91	303.0	COG0243@1|root,COG0243@2|Bacteria,2GJ62@201174|Actinobacteria,4E2T0@85010|Pseudonocardiales	201174|Actinobacteria	C	molybdopterin cofactor binding	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
TLS3_k127_5375058_2	1120948.KB903225_gene5576	9.394e-131	430.0	COG0019@1|root,COG0019@2|Bacteria,2HIAB@201174|Actinobacteria,4DXEU@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the Orn Lys Arg decarboxylase class-II family	-	-	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc,Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS3_k127_5375058_1	1120948.KB903225_gene5577	2.145e-197	644.0	COG0421@1|root,COG1586@1|root,COG0421@2|Bacteria,COG1586@2|Bacteria,2HIHC@201174|Actinobacteria,4DY0Q@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc,Spermine_synth
TLS3_k127_5375058_4	164757.Mjls_2763	1.293e-45	190.0	COG0824@1|root,COG0824@2|Bacteria,2IINH@201174|Actinobacteria,239K7@1762|Mycobacteriaceae	201174|Actinobacteria	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
TLS3_k127_5375058_0	1120948.KB903225_gene5581	5.841e-291	902.0	COG0365@1|root,COG0365@2|Bacteria,2GJSQ@201174|Actinobacteria,4DZ57@85010|Pseudonocardiales	201174|Actinobacteria	I	synthetase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_5375058_5	1120948.KB903225_gene5582	3.077e-27	113.0	2EUTX@1|root,33N9F@2|Bacteria,2GRIM@201174|Actinobacteria,4E6HF@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
TLS3_k127_5375058_3	2074.JNYD01000022_gene1508	4.824e-66	245.0	COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,4E2TH@85010|Pseudonocardiales	201174|Actinobacteria	O	PFAM AhpC TSA family	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
TLS3_k127_5385314_2	1120948.KB903217_gene1301	3.068e-31	131.0	COG1734@1|root,COG1734@2|Bacteria,2I16A@201174|Actinobacteria,4E6FX@85010|Pseudonocardiales	201174|Actinobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
TLS3_k127_5385314_0	2074.JNYD01000066_gene6458	4.142e-96	326.0	COG1597@1|root,COG1597@2|Bacteria,2HQQU@201174|Actinobacteria,4E9MR@85010|Pseudonocardiales	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
TLS3_k127_5385314_1	1306406.ASHX01000001_gene2455	1.604e-36	149.0	COG0546@1|root,COG0546@2|Bacteria,2GNCU@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,HAD_2,Hydrolase_like
TLS3_k127_5385314_3	1120948.KB903244_gene3112	1.201e-08	57.0	COG1546@1|root,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4E4GS@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
TLS3_k127_54002_2	1120948.KB903229_gene4957	1.359e-219	689.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4DXT3@85010|Pseudonocardiales	201174|Actinobacteria	C	Conserved region in glutamate synthase	lldD1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.2.3,1.1.3.15	ko:K00101,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00196,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0694	FMN_dh
TLS3_k127_54002_16	405948.SACE_2151	2.512e-80	273.0	COG0569@1|root,COG0569@2|Bacteria,2IA09@201174|Actinobacteria,4E0A6@85010|Pseudonocardiales	201174|Actinobacteria	P	K transport system, NAD-binding component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
TLS3_k127_54002_7	1137271.AZUM01000002_gene2968	8.854e-154	507.0	COG0168@1|root,COG0168@2|Bacteria,2GKKS@201174|Actinobacteria,4E16U@85010|Pseudonocardiales	201174|Actinobacteria	P	Trk-type K transport	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
TLS3_k127_54002_19	1137271.AZUM01000002_gene2992	5.934e-62	224.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4E3MF@85010|Pseudonocardiales	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
TLS3_k127_54002_17	1120948.KB903229_gene4955	7.903e-80	290.0	2BM8T@1|root,32FSI@2|Bacteria,2IG06@201174|Actinobacteria,4E3AU@85010|Pseudonocardiales	201174|Actinobacteria	S	tRNA adenosine	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_54002_4	1120948.KB903229_gene4954	2.808e-183	631.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4E039@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Peptidase family M20 M25 M40	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_54002_6	1120948.KB903229_gene4953	3.513e-154	494.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4DYDR@85010|Pseudonocardiales	201174|Actinobacteria	E	Prephenate dehydrogenase	tyrA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
TLS3_k127_54002_22	996637.SGM_2310	6.997e-22	112.0	COG5485@1|root,COG5485@2|Bacteria,2IKXY@201174|Actinobacteria	201174|Actinobacteria	S	Ester cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
TLS3_k127_54002_18	1120948.KB903229_gene4952	1.646e-75	263.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria,4EBG8@85010|Pseudonocardiales	201174|Actinobacteria	L	ATP dependent DNA ligase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
TLS3_k127_54002_9	1120948.KB903229_gene4951	9.217e-138	446.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria,4E10U@85010|Pseudonocardiales	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
TLS3_k127_54002_23	1120948.KB903229_gene4950	1.423e-17	96.0	COG2608@1|root,COG2608@2|Bacteria,2GXF6@201174|Actinobacteria,4EDAJ@85010|Pseudonocardiales	201174|Actinobacteria	P	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
TLS3_k127_54002_14	1120948.KB903229_gene4949	2.106e-90	312.0	COG0693@1|root,COG0693@2|Bacteria,2GMMW@201174|Actinobacteria,4E2ZX@85010|Pseudonocardiales	201174|Actinobacteria	S	Intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
TLS3_k127_54002_5	1120948.KB903229_gene4948	1.535e-156	519.0	COG3391@1|root,COG3391@2|Bacteria,2GMR0@201174|Actinobacteria,4DY0Z@85010|Pseudonocardiales	201174|Actinobacteria	S	amine dehydrogenase activity	lppL	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_54002_13	675635.Psed_0326	3.014e-107	366.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4DXB2@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Cell envelope-related transcriptional attenuator	lytR2	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
TLS3_k127_54002_21	1120948.KB903229_gene4942	1.487e-42	169.0	COG1309@1|root,COG1309@2|Bacteria,2IKGF@201174|Actinobacteria,4E76N@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_54002_1	1120948.KB903229_gene4941	2.435e-265	823.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria,4E05U@85010|Pseudonocardiales	201174|Actinobacteria	P	flavoprotein involved in K transport	-	GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0016491,GO:0016705,GO:0016709,GO:0055114	1.14.13.22	ko:K03379	ko00930,ko01120,ko01220,map00930,map01120,map01220	-	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko01000	-	-	-	FMO-like,K_oxygenase,Pyr_redox_3
TLS3_k127_54002_10	1120948.KB903229_gene4940	5.114e-131	449.0	COG4221@1|root,COG4221@2|Bacteria,2GKJ8@201174|Actinobacteria,4E08I@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_54002_8	1120948.KB903229_gene4939	1.522e-148	497.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4DZKK@85010|Pseudonocardiales	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
TLS3_k127_54002_12	1120948.KB903229_gene4938	4.769e-112	374.0	COG0443@1|root,COG0443@2|Bacteria	2|Bacteria	O	unfolded protein binding	-	-	-	ko:K18481	-	M00670	-	-	ko00000,ko00002,ko02000	3.A.1.27.4,3.A.1.27.5	-	-	HSP70
TLS3_k127_54002_11	1120948.KB903229_gene4937	1.674e-128	416.0	COG0266@1|root,COG0266@2|Bacteria,2GKCW@201174|Actinobacteria,4EANJ@85010|Pseudonocardiales	201174|Actinobacteria	L	Formamidopyrimidine-DNA glycosylase N-terminal domain	nei	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
TLS3_k127_54002_15	1120948.KB903240_gene4151	8.309e-89	313.0	COG3568@1|root,COG3568@2|Bacteria,2HEP6@201174|Actinobacteria,4E819@85010|Pseudonocardiales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_54002_3	1120948.KB903219_gene805	7.08e-188	628.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,2GK3B@201174|Actinobacteria,4DYZE@85010|Pseudonocardiales	201174|Actinobacteria	H	Uroporphyrin-III C-methyltransferase	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,TP_methylase
TLS3_k127_54002_0	1120948.KB903219_gene804	2.269e-273	859.0	COG0778@1|root,COG2038@1|root,COG0778@2|Bacteria,COG2038@2|Bacteria,2GJ16@201174|Actinobacteria,4E2AX@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT,Nitroreductase
TLS3_k127_54002_20	1120948.KB903219_gene803	3.749e-57	202.0	COG0079@1|root,COG0079@2|Bacteria,2I2ND@201174|Actinobacteria,4DYDQ@85010|Pseudonocardiales	201174|Actinobacteria	E	Aminotransferase class I and II	cobC	GO:0008150,GO:0040007	2.6.1.9,4.1.1.81	ko:K00817,ko:K04720	ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243,R06530	RC00006,RC00517,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,CbiG_C
TLS3_k127_5436966_2	710111.FraQA3DRAFT_2979	5.987e-83	299.0	COG2197@1|root,COG2197@2|Bacteria,2IC7E@201174|Actinobacteria,4EXDN@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_5436966_4	1237500.ANBA01000007_gene2757	6.021e-05	54.0	COG1840@1|root,COG1840@2|Bacteria,2I21F@201174|Actinobacteria,4EQAC@85012|Streptosporangiales	201174|Actinobacteria	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5436966_1	1445613.JALM01000005_gene1195	3.441e-104	343.0	COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria,4DYGM@85010|Pseudonocardiales	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
TLS3_k127_5436966_0	1120948.KB903244_gene3122	4.305e-216	676.0	COG2021@1|root,COG2021@2|Bacteria,2GKNJ@201174|Actinobacteria,4E0GU@85010|Pseudonocardiales	201174|Actinobacteria	E	alpha/beta hydrolase fold	-	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
TLS3_k127_5436966_3	1120948.KB903218_gene2074	7.888e-11	75.0	2B9SP@1|root,3235E@2|Bacteria,2H7R1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5441529_5	1120948.KB903217_gene1322	1.421e-84	286.0	COG1414@1|root,COG1414@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
TLS3_k127_5441529_0	1120948.KB903244_gene3049	1.767e-179	588.0	COG1944@1|root,COG1944@2|Bacteria	2|Bacteria	S	ATP diphosphatase activity	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
TLS3_k127_5441529_1	1120948.KB903244_gene3050	7.188e-157	503.0	COG0491@1|root,COG0491@2|Bacteria,2HP5U@201174|Actinobacteria,4DYA9@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_5441529_4	1380393.JHVP01000012_gene2827	1.363e-96	345.0	COG0673@1|root,COG0673@2|Bacteria,2IAXV@201174|Actinobacteria	201174|Actinobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
TLS3_k127_5441529_2	1120948.KB903244_gene3052	7.382e-138	462.0	COG0500@1|root,COG0500@2|Bacteria,2INXQ@201174|Actinobacteria,4EDFK@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
TLS3_k127_5441529_3	1120948.KB903244_gene3053	3.388e-110	372.0	COG1896@1|root,COG1896@2|Bacteria,2IGNT@201174|Actinobacteria	201174|Actinobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5441529_6	1120948.KB903244_gene3054	2.754e-78	263.0	COG1260@1|root,COG1260@2|Bacteria,2GJVN@201174|Actinobacteria,4DY1V@85010|Pseudonocardiales	201174|Actinobacteria	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
TLS3_k127_5455712_3	1120948.KB903232_gene4672	4.467e-60	226.0	COG2120@1|root,COG2120@2|Bacteria,2IA7G@201174|Actinobacteria,4E4UW@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TLS3_k127_5455712_1	298654.FraEuI1c_6537	1.645e-80	279.0	COG1960@1|root,COG1960@2|Bacteria,2GKK2@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
TLS3_k127_5455712_2	526225.Gobs_4916	1.703e-73	252.0	COG1309@1|root,COG1309@2|Bacteria,2IA4D@201174|Actinobacteria,4EW3S@85013|Frankiales	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	WHG
TLS3_k127_5455712_5	1380356.JNIK01000014_gene3193	6.559e-50	181.0	COG0251@1|root,COG0251@2|Bacteria,2IHQ7@201174|Actinobacteria,4EWM8@85013|Frankiales	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
TLS3_k127_5455712_0	1122921.KB898187_gene4522	1.894e-137	451.0	COG2267@1|root,COG2267@2|Bacteria,1TPI0@1239|Firmicutes,4HCKX@91061|Bacilli,26VII@186822|Paenibacillaceae	91061|Bacilli	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
TLS3_k127_5455712_4	1246474.ANBE01000011_gene3632	6.57e-55	197.0	COG0702@1|root,COG0702@2|Bacteria,2GK71@201174|Actinobacteria,4EN23@85012|Streptosporangiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
TLS3_k127_5455712_6	1120948.KB903229_gene5024	5.936e-20	93.0	COG1525@1|root,COG1525@2|Bacteria,2I38W@201174|Actinobacteria,4E45P@85010|Pseudonocardiales	201174|Actinobacteria	L	Excalibur calcium-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Excalibur,SNase
TLS3_k127_5486388_0	1120948.KB903217_gene1147	1.987e-170	540.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,2GJB4@201174|Actinobacteria,4E215@85010|Pseudonocardiales	201174|Actinobacteria	CE	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
TLS3_k127_5486388_1	1120948.KB903229_gene5289	2.371e-39	156.0	2CIBE@1|root,32S7P@2|Bacteria,2IRU5@201174|Actinobacteria,4E735@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5487751_0	1120948.KB903220_gene71	7.293e-89	308.0	COG1253@1|root,COG1253@2|Bacteria,2GIWR@201174|Actinobacteria,4DYNC@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM CBS domain	corC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
TLS3_k127_5487751_2	1120948.KB903220_gene70	2.977e-83	281.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4DXPA@85010|Pseudonocardiales	201174|Actinobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
TLS3_k127_5487751_1	675635.Psed_4487	7.375e-86	286.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4DY9G@85010|Pseudonocardiales	201174|Actinobacteria	T	Phosphate starvation-inducible protein PhoH	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
TLS3_k127_5491797_11	1120948.KB903243_gene2334	2.064e-76	279.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4E080@85010|Pseudonocardiales	201174|Actinobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
TLS3_k127_5491797_3	1120948.KB903243_gene2335	2.69e-126	412.0	COG0005@1|root,COG0005@2|Bacteria,2GKEI@201174|Actinobacteria,4DXJF@85010|Pseudonocardiales	201174|Actinobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009120,GO:0009164,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046121,GO:0046122,GO:0046124,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
TLS3_k127_5491797_13	1120948.KB903243_gene2336	2.569e-59	222.0	COG0655@1|root,COG0655@2|Bacteria,2II43@201174|Actinobacteria,4E3RY@85010|Pseudonocardiales	201174|Actinobacteria	S	Multimeric flavodoxin WrbA	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
TLS3_k127_5491797_6	1120948.KB903243_gene2337	8.62e-101	338.0	COG0604@1|root,COG0604@2|Bacteria,2GIWC@201174|Actinobacteria,4E35P@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
TLS3_k127_5491797_5	1449976.KALB_4205	1.77e-113	369.0	COG2207@1|root,COG2207@2|Bacteria,2GNRP@201174|Actinobacteria,4E4MV@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_5491797_9	1449976.KALB_4204	8.271e-93	311.0	COG0262@1|root,COG0262@2|Bacteria,2IGE7@201174|Actinobacteria,4EAHS@85010|Pseudonocardiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
TLS3_k127_5491797_14	1068980.ARVW01000001_gene4974	1.462e-51	183.0	2C6FT@1|root,334HA@2|Bacteria,2HCTI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5491797_4	1120948.KB903243_gene2338	1.34e-116	385.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4DXGC@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
TLS3_k127_5491797_0	1120948.KB903243_gene2339	1.464e-267	834.0	COG4346@1|root,COG4346@2|Bacteria,2GITT@201174|Actinobacteria,4DZAS@85010|Pseudonocardiales	201174|Actinobacteria	O	Dolichyl-phosphate-mannose--protein O-mannosyl transferase	pmt	GO:0000030,GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
TLS3_k127_5491797_1	405948.SACE_2647	3.013e-228	715.0	COG0160@1|root,COG0160@2|Bacteria,2I2F3@201174|Actinobacteria,4DX9J@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,4.1.1.64	ko:K00596,ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS3_k127_5491797_10	1961.JOAK01000016_gene5357	2.221e-89	303.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	2.1.1.288	ko:K15942	ko01057,ko01130,map01057,map01130	M00781	R06675,R06680	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
TLS3_k127_5491797_7	512565.AMIS_32760	1.273e-99	327.0	COG1695@1|root,COG1695@2|Bacteria,2IHK3@201174|Actinobacteria,4DJBT@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
TLS3_k127_5491797_15	675635.Psed_0802	0.0001298	49.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,4E8W0@85010|Pseudonocardiales	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TLS3_k127_5491797_12	1120948.KB903243_gene2344	2.306e-64	235.0	2EA6G@1|root,334B8@2|Bacteria,2GNTV@201174|Actinobacteria,4E3XM@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5491797_8	1120948.KB903243_gene2345	9.429e-94	321.0	COG1670@1|root,COG1670@2|Bacteria,2HAFI@201174|Actinobacteria,4DY57@85010|Pseudonocardiales	201174|Actinobacteria	J	PFAM Acetyltransferase (GNAT) family	rimJ	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
TLS3_k127_5491797_2	1120948.KB903243_gene2346	3.232e-159	508.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4E0D5@85010|Pseudonocardiales	201174|Actinobacteria	H	molybdopterin	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1,2.7.7.9	ko:K00963,ko:K03750	ko00040,ko00052,ko00500,ko00520,ko00790,ko01100,ko01130,map00040,map00052,map00500,map00520,map00790,map01100,map01130	M00129,M00361,M00362,M00549	R00289,R09735	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
TLS3_k127_5499844_0	1120948.KB903245_gene3477	0.0	1512.0	COG1038@1|root,COG1038@2|Bacteria,2H238@201174|Actinobacteria,4DYS5@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
TLS3_k127_5499844_1	1120948.KB903245_gene3478	1.064e-25	111.0	2ERCX@1|root,33IYJ@2|Bacteria,2ID8P@201174|Actinobacteria,4E7QH@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5505654_13	1298864.AUEQ01000001_gene4390	1.688e-36	155.0	COG0789@1|root,COG0789@2|Bacteria,2GNID@201174|Actinobacteria,23447@1762|Mycobacteriaceae	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
TLS3_k127_5505654_8	1380393.JHVP01000001_gene2095	1.617e-103	345.0	COG0702@1|root,COG0702@2|Bacteria,2GJB8@201174|Actinobacteria,4ES2V@85013|Frankiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
TLS3_k127_5505654_16	2074.JNYD01000026_gene666	3.636e-20	100.0	2AI15@1|root,318ES@2|Bacteria,2HE6F@201174|Actinobacteria,4ECZK@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5505654_2	1123320.KB889719_gene7354	3.847e-191	609.0	COG3211@1|root,COG3211@2|Bacteria,2GJKE@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
TLS3_k127_5505654_4	1120948.KB903243_gene2484	2.711e-184	589.0	COG0477@1|root,COG2814@2|Bacteria,2H4H5@201174|Actinobacteria,4E8H1@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_5505654_19	1265310.CCBD010000082_gene4932	3.768e-19	97.0	COG0664@1|root,COG1670@1|root,COG0664@2|Bacteria,COG1670@2|Bacteria,2HNCU@201174|Actinobacteria,234EN@1762|Mycobacteriaceae	201174|Actinobacteria	JT	cyclic nucleotide-binding	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,cNMP_binding
TLS3_k127_5505654_6	1068980.ARVW01000001_gene5636	2.996e-153	494.0	COG0208@1|root,COG0208@2|Bacteria,2GKGZ@201174|Actinobacteria	201174|Actinobacteria	F	PFAM Fatty acid desaturase, type 2	-	-	1.14.19.11,1.14.19.2,1.14.19.26	ko:K03921	ko00061,ko01040,ko01212,map00061,map01040,map01212	-	R03370,R08161,R11108,R11109	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase_2
TLS3_k127_5505654_10	1108045.GORHZ_145_00140	6.938e-62	226.0	2DBV7@1|root,2ZB9P@2|Bacteria,2IGRZ@201174|Actinobacteria,4GGB6@85026|Gordoniaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
TLS3_k127_5505654_15	1304865.JAGF01000001_gene432	1.812e-23	102.0	2DBV7@1|root,2ZB9P@2|Bacteria,2IGRZ@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
TLS3_k127_5505654_0	1380347.JNII01000008_gene4407	1.381e-298	940.0	COG2909@1|root,COG2909@2|Bacteria,2IBFJ@201174|Actinobacteria,4EX5E@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE,Pkinase
TLS3_k127_5505654_9	1120948.KB903243_gene2516	1.127e-63	231.0	COG2267@1|root,COG2267@2|Bacteria,2I9N6@201174|Actinobacteria	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_5505654_11	1463855.JOHV01000090_gene3405	3.452e-53	200.0	2CH5R@1|root,32S5B@2|Bacteria,2IQUR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
TLS3_k127_5505654_5	1123023.JIAI01000001_gene6256	5.405e-169	550.0	COG0028@1|root,COG0028@2|Bacteria,2GN3X@201174|Actinobacteria,4DZWK@85010|Pseudonocardiales	201174|Actinobacteria	EH	PFAM Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	ilvX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0030312,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
TLS3_k127_5505654_12	1120948.KB903222_gene575	2.844e-52	208.0	COG3012@1|root,COG3012@2|Bacteria,2IQEM@201174|Actinobacteria,4E5TY@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the UPF0225 family	ychJ	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
TLS3_k127_5505654_14	1114959.SZMC14600_20244	3.044e-36	144.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
TLS3_k127_5505654_7	2074.JNYD01000019_gene2459	8.594e-107	370.0	COG2141@1|root,COG2141@2|Bacteria,2GN4N@201174|Actinobacteria,4E0Y2@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_5505654_3	2074.JNYD01000019_gene2461	1.527e-185	610.0	COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria,4E5I7@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	ko:K14728	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
TLS3_k127_5505654_1	2074.JNYD01000019_gene2462	1.818e-244	760.0	COG1233@1|root,COG1233@2|Bacteria	2|Bacteria	Q	all-trans-retinol 13,14-reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
TLS3_k127_5505654_18	1120948.KB903221_gene507	2.035e-19	90.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria,4E45S@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_5522053_3	1429046.RR21198_3571	2.159e-68	244.0	COG4122@1|root,COG4122@2|Bacteria,2GP7A@201174|Actinobacteria,4FVJ3@85025|Nocardiaceae	201174|Actinobacteria	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
TLS3_k127_5522053_0	477641.MODMU_4613	2.84e-83	285.0	COG0346@1|root,COG0346@2|Bacteria,2HKRN@201174|Actinobacteria,4EV2A@85013|Frankiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS3_k127_5522053_2	1380356.JNIK01000014_gene3242	1.245e-76	267.0	COG0431@1|root,COG0431@2|Bacteria,2IHWU@201174|Actinobacteria,4ESVD@85013|Frankiales	201174|Actinobacteria	S	NADPH-dependent FMN reductase	ssuE	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
TLS3_k127_5522053_1	526225.Gobs_2154	1.166e-81	272.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,4ES7Y@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_5525241_1	1120948.KB903218_gene2177	1.137e-99	332.0	COG0342@1|root,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4DYZP@85010|Pseudonocardiales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
TLS3_k127_5525241_3	1120948.KB903218_gene2176	1.176e-34	150.0	COG1862@1|root,COG1862@2|Bacteria,2IQSP@201174|Actinobacteria,4E5KG@85010|Pseudonocardiales	201174|Actinobacteria	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
TLS3_k127_5525241_0	1120948.KB903218_gene2175	2.16e-188	599.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4DZHQ@85010|Pseudonocardiales	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
TLS3_k127_5525241_2	1120948.KB903218_gene2174	1.045e-39	150.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4E2QQ@85010|Pseudonocardiales	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
TLS3_k127_5542421_0	1120948.KB903243_gene2537	6.809e-204	642.0	COG2274@1|root,COG2274@2|Bacteria,2I2QC@201174|Actinobacteria,4EF8D@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
TLS3_k127_5542421_7	1120948.KB903243_gene2538	5.713e-50	182.0	COG1846@1|root,COG1846@2|Bacteria,2IHP0@201174|Actinobacteria,4E7D4@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
TLS3_k127_5542421_3	2074.JNYD01000020_gene2708	2.87e-97	326.0	arCOG06227@1|root,2ZCRG@2|Bacteria,2I96P@201174|Actinobacteria,4E3V0@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
TLS3_k127_5542421_8	2074.JNYD01000020_gene2707	4.534e-42	167.0	COG3764@1|root,COG3764@2|Bacteria,2IR30@201174|Actinobacteria,4E69E@85010|Pseudonocardiales	201174|Actinobacteria	M	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
TLS3_k127_5542421_6	2074.JNYD01000020_gene2706	7.122e-53	197.0	COG1595@1|root,COG1595@2|Bacteria,2IKQ7@201174|Actinobacteria,4E5VH@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	litS	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS3_k127_5542421_9	1449058.JQKT01000007_gene1080	6.414e-15	85.0	COG5343@1|root,COG5343@2|Bacteria,2IM7X@201174|Actinobacteria,4FPW6@85023|Microbacteriaceae	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
TLS3_k127_5542421_5	219305.MCAG_05073	7.897e-77	269.0	COG2172@1|root,COG2172@2|Bacteria,2GKU6@201174|Actinobacteria,4DBFR@85008|Micromonosporales	201174|Actinobacteria	T	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	prsR	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MEDS
TLS3_k127_5542421_2	390989.JOEG01000034_gene1667	1.897e-128	417.0	COG0596@1|root,COG0596@2|Bacteria,2GKT5@201174|Actinobacteria,4D95B@85008|Micromonosporales	201174|Actinobacteria	S	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
TLS3_k127_5542421_1	675635.Psed_6203	2.344e-161	522.0	COG2141@1|root,COG2141@2|Bacteria,2GMUP@201174|Actinobacteria,4EBZH@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_5542421_4	47716.JOFH01000019_gene4946	1.322e-93	313.0	COG2079@1|root,COG2079@2|Bacteria,2GKUR@201174|Actinobacteria	201174|Actinobacteria	S	MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
TLS3_k127_5544836_2	1120948.KB903218_gene1891	4.356e-65	222.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4E06H@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
TLS3_k127_5544836_6	1120948.KB903218_gene1894	1.036e-33	141.0	COG3544@1|root,COG3544@2|Bacteria,2IKUE@201174|Actinobacteria,4E4DB@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
TLS3_k127_5544836_3	1120948.KB903218_gene1899	8.408e-54	201.0	COG0241@1|root,COG0241@2|Bacteria,2H99P@201174|Actinobacteria	201174|Actinobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5544836_0	1120948.KB903218_gene1895	4.302e-122	415.0	COG2513@1|root,COG2513@2|Bacteria,2GJZZ@201174|Actinobacteria,4E0PY@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	4.1.3.32	ko:K20454	ko00760,ko01120,map00760,map01120	-	R01355	RC00286,RC01810	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
TLS3_k127_5544836_1	1120948.KB903218_gene1896	5.686e-82	278.0	COG1802@1|root,COG1802@2|Bacteria,2H1S8@201174|Actinobacteria,4E2XW@85010|Pseudonocardiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
TLS3_k127_5544836_5	1120948.KB903218_gene1897	1.031e-38	157.0	COG1335@1|root,COG1335@2|Bacteria,2I73B@201174|Actinobacteria,4E47F@85010|Pseudonocardiales	201174|Actinobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
TLS3_k127_5547030_4	1120948.KB903217_gene1159	1.112e-22	98.0	COG4221@1|root,COG4221@2|Bacteria,2GRRV@201174|Actinobacteria,4DXWQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_5547030_0	1120948.KB903217_gene1158	0.0	1145.0	COG0365@1|root,COG0365@2|Bacteria,2GP7N@201174|Actinobacteria,4DXMV@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA synthetase AMP-acid ligase	prpE	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
TLS3_k127_5547030_3	67352.JODS01000008_gene7269	1.113e-31	129.0	COG1846@1|root,COG1846@2|Bacteria,2IFW0@201174|Actinobacteria	201174|Actinobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
TLS3_k127_5547030_1	1110697.NCAST_05_04400	4.538e-115	386.0	COG0477@1|root,COG0477@2|Bacteria,2ID82@201174|Actinobacteria,4G8KH@85025|Nocardiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_5547030_2	1120948.KB903217_gene1157	2.662e-93	310.0	COG0402@1|root,COG0402@2|Bacteria,2GM63@201174|Actinobacteria,4E0CV@85010|Pseudonocardiales	201174|Actinobacteria	F	Amidohydrolase family	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
TLS3_k127_5547540_1	1120948.KB903222_gene610	1.037e-128	424.0	COG4825@1|root,COG4825@2|Bacteria,2GPAA@201174|Actinobacteria,4DZQ9@85010|Pseudonocardiales	201174|Actinobacteria	S	Thiamine pyrophosphokinase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TPPK_C
TLS3_k127_5547540_0	1120948.KB903222_gene611	4.641e-239	753.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4DZRF@85010|Pseudonocardiales	201174|Actinobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
TLS3_k127_5549960_3	1123023.JIAI01000006_gene56	5.147e-21	106.0	COG0425@1|root,COG0425@2|Bacteria,2I4E3@201174|Actinobacteria,4E932@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5549960_1	1123023.JIAI01000006_gene55	1.917e-119	414.0	COG3221@1|root,COG3221@2|Bacteria,2GK9B@201174|Actinobacteria,4E44Y@85010|Pseudonocardiales	201174|Actinobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
TLS3_k127_5549960_0	1123023.JIAI01000006_gene54	2.015e-145	473.0	COG1960@1|root,COG1960@2|Bacteria,2GZNN@201174|Actinobacteria,4DZP3@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_5549960_2	1123024.AUII01000059_gene540	9.818e-66	232.0	COG2208@1|root,COG2208@2|Bacteria,2GNG4@201174|Actinobacteria,4E0KW@85010|Pseudonocardiales	201174|Actinobacteria	KT	PFAM Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
TLS3_k127_55677_0	1120948.KB903244_gene3102	5.798e-280	877.0	COG1239@1|root,COG1240@1|root,COG1239@2|Bacteria,COG1240@2|Bacteria,2GN3S@201174|Actinobacteria,4DYER@85010|Pseudonocardiales	201174|Actinobacteria	H	von Willebrand factor, type A	chlI	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase,VWA_2
TLS3_k127_55677_2	1120948.KB903244_gene3101	8.354e-123	396.0	COG2109@1|root,COG2109@2|Bacteria,2GNJQ@201174|Actinobacteria,4DXWU@85010|Pseudonocardiales	201174|Actinobacteria	H	ATP corrinoid adenosyltransferase	cobO	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2849c	CobA_CobO_BtuR
TLS3_k127_55677_1	1120948.KB903244_gene3100	5.468e-191	613.0	COG1797@1|root,COG1797@2|Bacteria,2GJ3R@201174|Actinobacteria,4DXUP@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source	cobB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2,CbiA,GATase_3
TLS3_k127_55677_5	1292020.H483_0109425	1.079e-38	166.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_55677_4	1120948.KB903244_gene3092	1.395e-39	158.0	COG5416@1|root,COG5416@2|Bacteria,2GQTQ@201174|Actinobacteria,4E6KF@85010|Pseudonocardiales	201174|Actinobacteria	S	Lipopolysaccharide assembly protein A domain	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
TLS3_k127_55677_3	1120948.KB903244_gene3091	1.967e-56	206.0	COG0215@1|root,COG0215@2|Bacteria,2GJ4W@201174|Actinobacteria,4E1NY@85010|Pseudonocardiales	201174|Actinobacteria	J	PFAM tRNA synthetases class I (C) catalytic domain	-	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
TLS3_k127_5570395_4	1120948.KB903219_gene658	1.37e-105	349.0	COG2267@1|root,COG2267@2|Bacteria,2GUBM@201174|Actinobacteria,4E4XS@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	phaB	-	3.1.1.76	ko:K22250	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
TLS3_k127_5570395_1	1120948.KB903248_gene4202	4.188e-193	617.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DYYC@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
TLS3_k127_5570395_5	1123024.AUII01000002_gene942	8.399e-44	164.0	2F5EW@1|root,33Y0M@2|Bacteria,2IIHG@201174|Actinobacteria,4E3JJ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5570395_2	1120948.KB903219_gene660	9.975e-163	514.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria,4DZFF@85010|Pseudonocardiales	201174|Actinobacteria	L	Belongs to the FPG family	mutM1	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
TLS3_k127_5570395_0	1120948.KB903219_gene661	9.568e-215	686.0	COG3275@1|root,COG3275@2|Bacteria,2GJD4@201174|Actinobacteria,4DY27@85010|Pseudonocardiales	201174|Actinobacteria	T	PFAM histidine kinase	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
TLS3_k127_5570395_3	1120948.KB903219_gene662	5.848e-134	433.0	COG0616@1|root,COG0616@2|Bacteria,2HQDG@201174|Actinobacteria,4DXA5@85010|Pseudonocardiales	201174|Actinobacteria	OU	TIGRFAM signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773,ko:K04774	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
TLS3_k127_5585081_1	749927.AMED_4116	1.806e-42	161.0	COG1414@1|root,COG1414@2|Bacteria,2I9CD@201174|Actinobacteria,4DZGH@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
TLS3_k127_5585081_0	189753.AXAS01000003_gene4830	1.698e-111	370.0	COG2124@1|root,COG2124@2|Bacteria,1MY2E@1224|Proteobacteria,2TTFN@28211|Alphaproteobacteria,3JSSY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Cytochrome P450	MA20_22650	GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005506,GO:0006805,GO:0008150,GO:0008152,GO:0009410,GO:0009987,GO:0016491,GO:0016705,GO:0018690,GO:0020037,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071466,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	p450
TLS3_k127_5588833_10	330084.JNYZ01000016_gene5332	4.405e-30	134.0	COG0809@1|root,COG0809@2|Bacteria,2GN51@201174|Actinobacteria,4E2HP@85010|Pseudonocardiales	201174|Actinobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
TLS3_k127_5588833_7	266117.Rxyl_2616	2.441e-83	282.0	COG0346@1|root,COG1028@1|root,COG0346@2|Bacteria,COG1028@2|Bacteria,2HGA2@201174|Actinobacteria,4CSAC@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_5588833_6	675635.Psed_2507	1.563e-102	341.0	COG0583@1|root,COG0583@2|Bacteria,2IJ6X@201174|Actinobacteria,4E8AI@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS3_k127_5588833_2	675635.Psed_2508	7.077e-139	451.0	COG0620@1|root,COG0620@2|Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	2.1.1.14,4.4.1.23	ko:K00549,ko:K22363	ko00270,ko00450,ko00625,ko01100,ko01110,ko01230,map00270,map00450,map00625,map01100,map01110,map01230	M00017	R04405,R09365,R11897,R11899	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
TLS3_k127_5588833_3	1463854.JOHT01000001_gene2767	2.287e-135	437.0	COG0179@1|root,COG0179@2|Bacteria,2GMSJ@201174|Actinobacteria	201174|Actinobacteria	Q	fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
TLS3_k127_5588833_1	2074.JNYD01000026_gene669	9.185e-167	531.0	COG0491@1|root,COG0491@2|Bacteria,2HFVZ@201174|Actinobacteria,4DY1J@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	ko:K05555	ko01057,ko01130,map01057,map01130	M00778	R09305	-	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	Lactamase_B
TLS3_k127_5588833_0	1120948.KB903220_gene146	2.621e-180	573.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4E3A8@85010|Pseudonocardiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_5588833_5	1120948.KB903218_gene2157	2.286e-125	411.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,2I2RA@201174|Actinobacteria,4E9MN@85010|Pseudonocardiales	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
TLS3_k127_5588833_4	477641.MODMU_5139	2.444e-132	428.0	COG0451@1|root,COG0451@2|Bacteria,2GJ23@201174|Actinobacteria,4ETRF@85013|Frankiales	201174|Actinobacteria	GM	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
TLS3_k127_5588833_9	477641.MODMU_5140	5.251e-64	224.0	COG1309@1|root,COG1309@2|Bacteria,2GNHX@201174|Actinobacteria,4EVRA@85013|Frankiales	201174|Actinobacteria	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_5588833_8	330084.JNYZ01000011_gene7294	9.127e-67	230.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4DYU2@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
TLS3_k127_5615868_0	1123023.JIAI01000002_gene5639	1.256e-23	116.0	COG1403@1|root,COG1403@2|Bacteria,2INVR@201174|Actinobacteria	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
TLS3_k127_5638753_2	1120948.KB903244_gene2978	1.81e-187	593.0	COG1196@1|root,COG1196@2|Bacteria,2GJBD@201174|Actinobacteria,4DXH7@85010|Pseudonocardiales	201174|Actinobacteria	D	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
TLS3_k127_5638753_4	1120948.KB903244_gene2991	1.881e-41	168.0	2F4G5@1|root,33X67@2|Bacteria,2IRZ3@201174|Actinobacteria,4E5KT@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5638753_0	1120948.KB903244_gene2992	4.861e-267	829.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4DXJ9@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
TLS3_k127_5638753_3	1123024.AUII01000006_gene4693	3.703e-69	248.0	COG2358@1|root,COG2358@2|Bacteria,2GKQJ@201174|Actinobacteria,4E1MT@85010|Pseudonocardiales	201174|Actinobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
TLS3_k127_5638753_1	882082.SaccyDRAFT_5054	4.633e-228	719.0	COG1115@1|root,COG1115@2|Bacteria,2GIU2@201174|Actinobacteria,4DZWP@85010|Pseudonocardiales	201174|Actinobacteria	E	TIGRFAM amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
TLS3_k127_5644769_0	1120948.KB903240_gene4175	8.021e-181	572.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4E04A@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.8.12	ko:K00248,ko:K14448	ko00071,ko00280,ko00630,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00630,map00650,map01100,map01110,map01120,map01200,map01212	M00373	R01175,R01178,R02661,R03172,R04751,R09293	RC00052,RC00068,RC00076,RC00120,RC00148,RC02483	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_5644769_2	1120948.KB903244_gene2808	2.324e-132	455.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4E0AR@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_5644769_1	1120948.KB903244_gene2807	2.308e-142	471.0	COG0596@1|root,COG0596@2|Bacteria,2HCC5@201174|Actinobacteria,4DXCR@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
TLS3_k127_5645811_0	1120948.KB903217_gene871	1.276e-155	509.0	COG4948@1|root,COG4948@2|Bacteria,2IBIE@201174|Actinobacteria,4EENZ@85010|Pseudonocardiales	201174|Actinobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.5.1.27	ko:K18983	ko00053,map00053	-	R10847	RC03287	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
TLS3_k127_5645811_2	1120948.KB903217_gene869	1.56e-44	182.0	2B5Y2@1|root,31YU2@2|Bacteria,2H193@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5645811_1	1120948.KB903217_gene870	3.641e-65	238.0	COG1414@1|root,COG1414@2|Bacteria,2IC69@201174|Actinobacteria,4E4VN@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
TLS3_k127_5645811_3	1380356.JNIK01000019_gene403	7.286e-25	109.0	COG2258@1|root,COG2258@2|Bacteria,2IH5Z@201174|Actinobacteria,4EWDR@85013|Frankiales	201174|Actinobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5645811_4	1120948.KB903217_gene863	1.642e-12	75.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4E0PH@85010|Pseudonocardiales	201174|Actinobacteria	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_5651393_2	1120948.KB903219_gene798	0.000307	45.0	COG2759@1|root,COG2759@2|Bacteria,2GT0X@201174|Actinobacteria,4DXJB@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
TLS3_k127_5651393_0	1077974.GOEFS_119_00120	7.259e-23	110.0	2DJNQ@1|root,306RM@2|Bacteria,2H36W@201174|Actinobacteria,4GDU4@85026|Gordoniaceae	201174|Actinobacteria	S	Cutinase	-	-	-	-	-	-	-	-	-	-	-	-	Cutinase
TLS3_k127_5651393_3	1120948.KB903219_gene797	0.0008264	43.0	COG0679@1|root,COG0679@2|Bacteria,2GNIA@201174|Actinobacteria,4E3VW@85010|Pseudonocardiales	201174|Actinobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
TLS3_k127_5655972_1	1120948.KB903229_gene5136	1.974e-83	299.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4DXQ1@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
TLS3_k127_5655972_0	1120948.KB903229_gene5047	3.575e-88	310.0	COG1295@1|root,COG1295@2|Bacteria,2HMYQ@201174|Actinobacteria,4E4Y5@85010|Pseudonocardiales	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
TLS3_k127_5655972_3	593907.Celgi_2296	1.104e-06	61.0	COG0515@1|root,COG0515@2|Bacteria,2IAZC@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,Pkinase
TLS3_k127_5655972_2	1120948.KB903229_gene5138	9.924e-51	181.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4E2XM@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
TLS3_k127_5669501_1	1120948.KB903229_gene5362	3.633e-106	353.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4E178@85010|Pseudonocardiales	201174|Actinobacteria	V	MacB-like periplasmic core domain	yknZ	-	-	ko:K02004,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	FtsX,MacB_PCD
TLS3_k127_5669501_0	1120948.KB903229_gene5361	6.209e-108	364.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4DXK6@85010|Pseudonocardiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_5669501_2	1120948.KB903229_gene5360	3.55e-56	203.0	COG0845@1|root,COG0845@2|Bacteria,2H154@201174|Actinobacteria,4DZ36@85010|Pseudonocardiales	201174|Actinobacteria	M	HlyD family secretion protein	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
TLS3_k127_5689743_1	1246995.AFR_39230	2.298e-73	258.0	COG3238@1|root,COG3238@2|Bacteria,2IB1U@201174|Actinobacteria,4DBCE@85008|Micromonosporales	201174|Actinobacteria	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
TLS3_k127_5689743_0	1120948.KB903217_gene1659	1.042e-147	473.0	COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4DYIH@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0040007,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
TLS3_k127_5692530_5	1120948.KB903248_gene4293	4.242e-34	134.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4DXA2@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	crtE	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
TLS3_k127_5692530_0	1120948.KB903248_gene4294	7.773e-228	716.0	COG1233@1|root,COG1233@2|Bacteria,2GJAV@201174|Actinobacteria,4DXS1@85010|Pseudonocardiales	201174|Actinobacteria	Q	phytoene	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
TLS3_k127_5692530_1	1120948.KB903248_gene4295	8.153e-137	462.0	COG1562@1|root,COG1562@2|Bacteria,2GJN2@201174|Actinobacteria,4DY9Y@85010|Pseudonocardiales	201174|Actinobacteria	I	phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
TLS3_k127_5692530_7	566461.SSFG_07583	4.136e-07	63.0	COG3200@1|root,COG3200@2|Bacteria,2IJ8X@201174|Actinobacteria	201174|Actinobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5692530_4	1120948.KB903248_gene4297	1.086e-49	182.0	2E0H9@1|root,32W34@2|Bacteria,2IHPW@201174|Actinobacteria,4E56C@85010|Pseudonocardiales	201174|Actinobacteria	S	transcriptional regulator	-	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010565,GO:0016310,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5692530_3	365528.KB891262_gene5085	3.002e-75	259.0	COG2267@1|root,COG2267@2|Bacteria,2I1RU@201174|Actinobacteria,4EV6M@85013|Frankiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
TLS3_k127_5692530_2	1120948.KB903248_gene4298	1.404e-132	437.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4DXBC@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
TLS3_k127_5692530_6	1194972.MVAC_13191	4.442e-29	115.0	COG3200@1|root,COG3200@2|Bacteria,2GJBX@201174|Actinobacteria,233JQ@1762|Mycobacteriaceae	201174|Actinobacteria	E	Belongs to the class-II DAHP synthase family	aroG	GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016043,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0022607,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2178c	DAHP_synth_2
TLS3_k127_5698203_1	1120948.KB903245_gene3476	1.806e-65	228.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4E45R@85010|Pseudonocardiales	201174|Actinobacteria	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
TLS3_k127_5698203_0	1120948.KB903245_gene3477	4.89e-111	361.0	COG1038@1|root,COG1038@2|Bacteria,2H238@201174|Actinobacteria,4DYS5@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
TLS3_k127_5698741_1	1120948.KB903240_gene3995	9.877e-163	541.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4E00M@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
TLS3_k127_5698741_0	1120948.KB903240_gene3996	6.64e-228	724.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,4DYUR@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1599	Histidinol_dh
TLS3_k127_5698741_2	1120948.KB903240_gene3998	2.287e-72	250.0	COG5297@1|root,COG5297@2|Bacteria,2HDPZ@201174|Actinobacteria,4E329@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 12	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_12,RicinB_lectin_2,Ricin_B_lectin
TLS3_k127_5711095_0	675635.Psed_1172	6.208e-177	572.0	COG1835@1|root,COG1835@2|Bacteria,2GKI5@201174|Actinobacteria,4DYJ7@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS3_k127_5711095_1	1120948.KB903243_gene2600	7.986e-152	502.0	COG3673@1|root,COG3673@2|Bacteria,2ID7N@201174|Actinobacteria,4E6DP@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
TLS3_k127_5711095_2	1463857.JOFZ01000012_gene1777	4.172e-18	93.0	2DPU0@1|root,333DA@2|Bacteria,2IARZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5714661_2	43354.JOIJ01000006_gene1852	2.266e-115	372.0	COG2309@1|root,COG2309@2|Bacteria,2I8N4@201174|Actinobacteria,4DZ0T@85010|Pseudonocardiales	201174|Actinobacteria	E	aminopeptidase activity	nicX	-	1.13.11.9	ko:K18028	ko00760,ko01120,map00760,map01120	M00622	R09125	RC02430	ko00000,ko00001,ko00002,ko01000	-	-	-	-
TLS3_k127_5714661_1	43354.JOIJ01000006_gene1851	1.143e-125	406.0	COG3473@1|root,COG3473@2|Bacteria,2HRMA@201174|Actinobacteria,4E1YT@85010|Pseudonocardiales	201174|Actinobacteria	Q	Catalyzes the conversion of maleate to fumarate	maiA	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Glu_race
TLS3_k127_5714661_0	1068978.AMETH_3942	2.945e-128	417.0	COG0596@1|root,COG0596@2|Bacteria,2H5NQ@201174|Actinobacteria,4E28U@85010|Pseudonocardiales	201174|Actinobacteria	Q	Serine aminopeptidase, S33	-	-	3.5.1.106	ko:K15357	ko00760,ko01120,map00760,map01120	M00622	R09126	RC00323,RC02431	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,Isochorismatase
TLS3_k127_5714661_3	1068978.AMETH_3943	1.099e-91	311.0	COG1335@1|root,COG1335@2|Bacteria,2HKSW@201174|Actinobacteria,4E2X7@85010|Pseudonocardiales	201174|Actinobacteria	Q	Isochorismatase family	-	-	3.5.1.107	ko:K13995	ko00760,ko01120,map00760,map01120	M00622	R03540	RC00950	ko00000,ko00001,ko00002,ko01000	-	-	-	Isochorismatase
TLS3_k127_5714661_4	1089544.KB912942_gene1441	1.482e-12	70.0	COG3427@1|root,COG3427@2|Bacteria,2IBJB@201174|Actinobacteria,4E4WB@85010|Pseudonocardiales	201174|Actinobacteria	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
TLS3_k127_5730140_3	43354.JOIJ01000002_gene4200	1.025e-23	102.0	COG0679@1|root,COG0679@2|Bacteria,2GNIA@201174|Actinobacteria,4E3VW@85010|Pseudonocardiales	201174|Actinobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
TLS3_k127_5730140_0	1120948.KB903218_gene2259	1.228e-163	524.0	COG0477@1|root,COG2814@2|Bacteria,2GK8C@201174|Actinobacteria,4DZMT@85010|Pseudonocardiales	201174|Actinobacteria	EGP	arabinose efflux permease	-	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1
TLS3_k127_5730140_2	1120948.KB903218_gene2258	3.132e-111	367.0	COG0583@1|root,COG0583@2|Bacteria,2HMI8@201174|Actinobacteria,4E021@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS3_k127_5730140_1	1120948.KB903218_gene2073	1.389e-117	384.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4E0AX@85010|Pseudonocardiales	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
TLS3_k127_5733746_2	1120948.KB903228_gene4822	3.71e-88	292.0	COG0318@1|root,COG0318@2|Bacteria,2GKDF@201174|Actinobacteria,4DYWP@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	fadD9	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C,Polyketide_cyc2
TLS3_k127_5733746_3	1463825.JNXC01000005_gene2389	2.217e-46	173.0	COG3402@1|root,COG3402@2|Bacteria,2IQFA@201174|Actinobacteria,4E4IJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	ko:K09167	-	-	-	-	ko00000	-	-	-	bPH_2
TLS3_k127_5733746_0	1123023.JIAI01000006_gene129	3.769e-109	378.0	COG3428@1|root,COG3428@2|Bacteria,2GJCD@201174|Actinobacteria,4DXCP@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Bacterial membrane flanked domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
TLS3_k127_5733746_1	1120948.KB903228_gene4824	2.631e-101	336.0	COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,4DYV4@85010|Pseudonocardiales	201174|Actinobacteria	A	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
TLS3_k127_5733746_5	1120948.KB903228_gene4825	3.91e-27	123.0	COG0662@1|root,COG0662@2|Bacteria,2GTM8@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_5733746_4	1123024.AUII01000012_gene4211	2.567e-34	139.0	COG0582@1|root,COG0582@2|Bacteria,2GTYQ@201174|Actinobacteria,4DXK2@85010|Pseudonocardiales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
TLS3_k127_5740138_11	1120948.KB903243_gene2669	3.199e-76	291.0	COG2199@1|root,COG3706@2|Bacteria,2I8IE@201174|Actinobacteria,4DZS3@85010|Pseudonocardiales	201174|Actinobacteria	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
TLS3_k127_5740138_15	1120948.KB903243_gene2668	2.996e-43	181.0	COG0671@1|root,COG0671@2|Bacteria,2HNCK@201174|Actinobacteria,4E7S1@85010|Pseudonocardiales	201174|Actinobacteria	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
TLS3_k127_5740138_4	858619.CVAR_1657	1.335e-154	506.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,22M2Q@1653|Corynebacteriaceae	201174|Actinobacteria	EGP	Permeases of the major facilitator superfamily	-	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
TLS3_k127_5740138_10	335543.Sfum_0958	9.993e-84	293.0	COG3919@1|root,COG3919@2|Bacteria,1R94Z@1224|Proteobacteria,42U1R@68525|delta/epsilon subdivisions,2X2JR@28221|Deltaproteobacteria,2MS8F@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5740138_8	886293.Sinac_3905	7.318e-91	309.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_5740138_17	1120948.KB903219_gene709	6.578e-37	156.0	2EI5Z@1|root,33BXC@2|Bacteria	2|Bacteria	S	Polysaccharide lyase	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4,Polysacc_lyase
TLS3_k127_5740138_6	675635.Psed_1882	3e-127	432.0	COG2244@1|root,COG2244@2|Bacteria,2H55P@201174|Actinobacteria,4DY6N@85010|Pseudonocardiales	201174|Actinobacteria	S	Polysaccharide biosynthesis protein	-	-	-	ko:K03328,ko:K16695	-	-	-	-	ko00000,ko02000	2.A.66.2,2.A.66.2.7	-	-	Polysacc_synt_3,Polysacc_synt_C
TLS3_k127_5740138_16	1120948.KB903243_gene2521	1.342e-40	166.0	2EI5Z@1|root,33BXC@2|Bacteria	2|Bacteria	S	Polysaccharide lyase	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4,Polysacc_lyase
TLS3_k127_5740138_2	1123024.AUII01000022_gene99	8.783e-173	561.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4E1HD@85010|Pseudonocardiales	201174|Actinobacteria	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	rfbP	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
TLS3_k127_5740138_0	1120948.KB903243_gene2661	7.206e-238	740.0	COG0500@1|root,COG0500@2|Bacteria,2GMXG@201174|Actinobacteria,4DX79@85010|Pseudonocardiales	201174|Actinobacteria	Q	C-methyltransferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
TLS3_k127_5740138_5	1120948.KB903243_gene2660	2.516e-144	472.0	COG1208@1|root,COG1208@2|Bacteria,2GKHA@201174|Actinobacteria,4DZ7Z@85010|Pseudonocardiales	201174|Actinobacteria	JM	Glucose-1-phosphate cytidylyltransferase	rfbF	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
TLS3_k127_5740138_7	1120948.KB903243_gene2659	5.043e-114	371.0	COG2120@1|root,COG2120@2|Bacteria,2GMXC@201174|Actinobacteria,4E34R@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TLS3_k127_5740138_1	1120948.KB903243_gene2658	2.707e-179	582.0	COG0451@1|root,COG0451@2|Bacteria,2GNYX@201174|Actinobacteria,4E1KX@85010|Pseudonocardiales	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS3_k127_5740138_9	675635.Psed_1893	2.159e-85	294.0	COG1898@1|root,COG1898@2|Bacteria,2GMW4@201174|Actinobacteria,4E2K9@85010|Pseudonocardiales	201174|Actinobacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
TLS3_k127_5740138_3	1120948.KB903243_gene2656	2.552e-170	544.0	COG0001@1|root,COG0001@2|Bacteria,2GKJV@201174|Actinobacteria,4E1SS@85010|Pseudonocardiales	201174|Actinobacteria	H	Putative zinc binding domain	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,Methyltransf_13,Methyltransf_14,Methyltransf_23
TLS3_k127_5740138_14	1230476.C207_02144	2.209e-65	250.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2TR88@28211|Alphaproteobacteria,3K0MM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_2
TLS3_k127_5740138_12	1206741.BAFX01000183_gene7614	3.065e-70	253.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,Sulfotransfer_3
TLS3_k127_5740138_13	675635.Psed_6073	4.039e-69	246.0	COG5492@1|root,COG5492@2|Bacteria,2IFQX@201174|Actinobacteria	201174|Actinobacteria	N	Polysaccharide lyase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_lyase
TLS3_k127_5740138_18	329726.AM1_5712	3.691e-34	146.0	COG2931@1|root,COG2931@2|Bacteria,1G0Z8@1117|Cyanobacteria	1117|Cyanobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5758533_0	298655.KI912266_gene2838	9.26e-300	949.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4ERMH@85013|Frankiales	201174|Actinobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
TLS3_k127_5758533_1	1123024.AUII01000021_gene64	5.976e-13	77.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria,4E6H3@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
TLS3_k127_5758533_2	1123024.AUII01000010_gene749	2.42e-10	71.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
TLS3_k127_5758533_3	1123023.JIAI01000006_gene269	1.025e-09	71.0	COG1403@1|root,COG1403@2|Bacteria,2INVR@201174|Actinobacteria	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
TLS3_k127_57706_4	471857.Svir_19070	1.657e-67	234.0	COG3327@1|root,COG3327@2|Bacteria,2GNME@201174|Actinobacteria,4DXAA@85010|Pseudonocardiales	201174|Actinobacteria	K	Phenylacetic acid-responsive transcriptional repressor	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
TLS3_k127_57706_5	1123320.KB889664_gene1334	1.493e-40	154.0	COG1846@1|root,COG1846@2|Bacteria,2IFEY@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
TLS3_k127_57706_2	2074.JNYD01000026_gene654	1.326e-111	366.0	COG1024@1|root,COG1024@2|Bacteria,2ICPU@201174|Actinobacteria,4EAJG@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.155	ko:K20036	ko00920,map00920	-	R10936	RC00004,RC03306,RC03307	ko00000,ko00001,ko01000	-	-	-	ECH_1
TLS3_k127_57706_0	1123320.KB889664_gene1331	3.029e-266	859.0	COG0365@1|root,COG0365@2|Bacteria,2GM20@201174|Actinobacteria	201174|Actinobacteria	I	TIGRFAM Acetoacetyl-CoA synthase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
TLS3_k127_57706_3	2074.JNYD01000026_gene652	1.139e-107	383.0	COG1250@1|root,COG1250@2|Bacteria,2GNXI@201174|Actinobacteria,4DYQR@85010|Pseudonocardiales	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.108	ko:K17735	-	-	-	-	ko00000,ko01000	-	-	-	3HCDH,3HCDH_N
TLS3_k127_57706_1	2074.JNYD01000022_gene1433	1.037e-150	486.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria,4DZEJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
TLS3_k127_57706_6	1288083.AUKR01000007_gene3220	2.76e-16	83.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_5781698_13	28444.JODQ01000014_gene6934	3.784e-24	109.0	COG3619@1|root,COG3619@2|Bacteria,2I155@201174|Actinobacteria,4EKYU@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF1275)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
TLS3_k127_5781698_0	2074.JNYD01000005_gene3198	7.807e-165	535.0	COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria,4DYSX@85010|Pseudonocardiales	201174|Actinobacteria	E	succinyl-diaminopimelate desuccinylase	dapE	GO:0008150,GO:0040007	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
TLS3_k127_5781698_5	1120948.KB903246_gene3309	8.078e-97	327.0	COG0655@1|root,COG0655@2|Bacteria,2GTN2@201174|Actinobacteria,4E28Q@85010|Pseudonocardiales	201174|Actinobacteria	S	NADPH-dependent FMN reductase	wrbA	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
TLS3_k127_5781698_3	1120948.KB903246_gene3308	5.132e-133	428.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4DYE4@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
TLS3_k127_5781698_9	1120948.KB903246_gene3307	4.132e-61	225.0	COG1611@1|root,COG1611@2|Bacteria,2GMM1@201174|Actinobacteria,4E2JN@85010|Pseudonocardiales	201174|Actinobacteria	S	Cytokinin riboside 5'-monophosphate phosphoribohydrolase	-	GO:0003674,GO:0003824,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009690,GO:0009691,GO:0009987,GO:0010817,GO:0016787,GO:0016798,GO:0016799,GO:0034754,GO:0042445,GO:0042446,GO:0044237,GO:0044249,GO:0046483,GO:0065007,GO:0065008,GO:0071704,GO:1901564	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
TLS3_k127_5781698_4	1123024.AUII01000003_gene3353	1.964e-118	400.0	COG0294@1|root,COG0294@2|Bacteria,2GJNI@201174|Actinobacteria,4DXUC@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
TLS3_k127_5781698_2	1120948.KB903246_gene3306	6.714e-139	454.0	COG0463@1|root,COG0463@2|Bacteria,2I2NK@201174|Actinobacteria,4E09C@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	gpgS	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006011,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009225,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0034641,GO:0040007,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046983,GO:0055086,GO:0071704,GO:1901135,GO:1901360	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2
TLS3_k127_5781698_11	1120948.KB903246_gene3305	3.998e-30	136.0	COG3599@1|root,COG3599@2|Bacteria,2I1AP@201174|Actinobacteria,4E5E2@85010|Pseudonocardiales	201174|Actinobacteria	D	regulation of cell shape	-	-	-	-	-	-	-	-	-	-	-	-	DivIVA
TLS3_k127_5781698_10	65497.JODV01000001_gene3755	2.314e-40	162.0	COG3427@1|root,COG3427@2|Bacteria,2II8Y@201174|Actinobacteria,4E5GT@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_5781698_7	1120948.KB903246_gene3303	3.586e-76	266.0	COG2818@1|root,COG2818@2|Bacteria,2IFH0@201174|Actinobacteria,4E2RI@85010|Pseudonocardiales	201174|Actinobacteria	L	TIGRFAM DNA-3-methyladenine glycosylase I	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
TLS3_k127_5781698_14	1120948.KB903246_gene3302	6.912e-24	102.0	2E39N@1|root,32Y97@2|Bacteria,2GQFF@201174|Actinobacteria,4E6N0@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3117
TLS3_k127_5781698_1	994479.GL877878_gene1936	4.999e-140	467.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,4DYF9@85010|Pseudonocardiales	201174|Actinobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
TLS3_k127_5781698_8	1120948.KB903246_gene3300	2.173e-74	258.0	COG4122@1|root,COG4122@2|Bacteria,2GPEV@201174|Actinobacteria,4E04Q@85010|Pseudonocardiales	201174|Actinobacteria	S	O-methyltransferase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
TLS3_k127_5781698_6	1120948.KB903246_gene3299	4.721e-88	311.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria,4DYCJ@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_5781698_12	1120948.KB903246_gene3298	7.538e-30	124.0	COG5662@1|root,COG5662@2|Bacteria,2HMM4@201174|Actinobacteria,4E4FI@85010|Pseudonocardiales	201174|Actinobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
TLS3_k127_5791229_0	1120948.KB903244_gene2929	4.121e-222	699.0	COG0454@1|root,COG1042@1|root,COG0456@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4DYY0@85010|Pseudonocardiales	201174|Actinobacteria	CK	Acyl-CoA synthetase (NDP forming)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
TLS3_k127_5791642_2	1120948.KB903240_gene3801	5.103e-118	397.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4E1PW@85010|Pseudonocardiales	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	GO:0006950,GO:0008150,GO:0050896,GO:0051409	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
TLS3_k127_5791642_1	1120948.KB903240_gene3802	1.524e-151	488.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4E0H4@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_5791642_4	1120948.KB903240_gene3803	5.464e-23	113.0	2EGVE@1|root,33AMN@2|Bacteria,2GRZT@201174|Actinobacteria,4E6KC@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5791642_6	1120948.KB903240_gene3804	1.069e-13	71.0	COG0604@1|root,COG0604@2|Bacteria,2GK7Y@201174|Actinobacteria,4DZMC@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_5791642_3	1120948.KB903240_gene3804	8.823e-110	383.0	COG0604@1|root,COG0604@2|Bacteria,2GK7Y@201174|Actinobacteria,4DZMC@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_5791642_0	1120948.KB903240_gene3806	1.067e-256	795.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria,4DXH1@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Peptidase family M20 M25 M40	dapE2	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
TLS3_k127_5791642_5	65497.JODV01000018_gene3035	3.071e-21	97.0	COG1506@1|root,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4E0AD@85010|Pseudonocardiales	201174|Actinobacteria	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
TLS3_k127_5802819_3	1120948.KB903217_gene1682	1.261e-89	299.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria,4E05U@85010|Pseudonocardiales	201174|Actinobacteria	P	flavoprotein involved in K transport	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,K_oxygenase,Pyr_redox_2,Pyr_redox_3
TLS3_k127_5802819_1	1120948.KB903217_gene1683	4.872e-152	488.0	COG1295@1|root,COG1295@2|Bacteria,2GN79@201174|Actinobacteria,4DZYZ@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM YihY family protein (not ribonuclease BN)	yhjD	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
TLS3_k127_5802819_0	1120948.KB903218_gene2096	4.865e-154	497.0	COG2508@1|root,COG2508@2|Bacteria,2GP6C@201174|Actinobacteria,4E1GM@85010|Pseudonocardiales	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
TLS3_k127_5802819_2	2074.JNYD01000012_gene192	1.773e-126	414.0	COG0657@1|root,COG0657@2|Bacteria,2GJYR@201174|Actinobacteria,4EEQM@85010|Pseudonocardiales	201174|Actinobacteria	I	Carboxylesterase family	lipI	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009056,GO:0016787,GO:0016788,GO:0034338,GO:0052689	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
TLS3_k127_5802819_4	1120948.KB903218_gene2098	1.137e-43	176.0	COG2072@1|root,COG2072@2|Bacteria,2H38Q@201174|Actinobacteria,4EA65@85010|Pseudonocardiales	201174|Actinobacteria	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,NAD_binding_8,Pyr_redox_2
TLS3_k127_5844431_3	1120948.KB903217_gene1322	2.368e-52	190.0	COG1414@1|root,COG1414@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
TLS3_k127_5844431_0	1120948.KB903217_gene1321	4.908e-227	721.0	COG3284@1|root,COG3284@2|Bacteria,2IANR@201174|Actinobacteria,4DZMK@85010|Pseudonocardiales	201174|Actinobacteria	KQ	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HTH_8
TLS3_k127_5844431_4	1120948.KB903217_gene1319	1.121e-40	161.0	COG1259@1|root,COG1259@2|Bacteria,2H80K@201174|Actinobacteria,4ECEW@85010|Pseudonocardiales	201174|Actinobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
TLS3_k127_5844431_6	1123024.AUII01000035_gene1214	1.532e-15	88.0	28YMP@1|root,2ZKFB@2|Bacteria,2GZDU@201174|Actinobacteria,4E7TC@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5844431_1	1120948.KB903217_gene1317	4.043e-76	275.0	2F8IB@1|root,340X4@2|Bacteria,2INMP@201174|Actinobacteria,4E51Z@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5844431_2	1120948.KB903217_gene1316	1.476e-62	216.0	COG2151@1|root,COG2151@2|Bacteria,2IAEQ@201174|Actinobacteria,4E453@85010|Pseudonocardiales	201174|Actinobacteria	S	metal-sulfur cluster biosynthetic enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
TLS3_k127_5856564_5	1120948.KB903245_gene3705	3.267e-24	119.0	COG0515@1|root,COG0515@2|Bacteria	1120948.KB903245_gene3705|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5856564_0	1120948.KB903245_gene3707	1.064e-310	957.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DXDJ@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_5856564_2	1120948.KB903245_gene3710	6.292e-57	209.0	COG0607@1|root,COG0607@2|Bacteria,2IKTC@201174|Actinobacteria,4E4YE@85010|Pseudonocardiales	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
TLS3_k127_5856564_1	1120948.KB903245_gene3711	7.392e-75	258.0	COG5553@1|root,COG5553@2|Bacteria,2I2T6@201174|Actinobacteria,4E3IC@85010|Pseudonocardiales	201174|Actinobacteria	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	CDO_I
TLS3_k127_5856564_4	1068980.ARVW01000001_gene4627	2.838e-25	117.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4DXBD@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS3_k127_5864741_0	1120948.KB903240_gene4172	3.989e-188	592.0	COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria,4E8PX@85010|Pseudonocardiales	201174|Actinobacteria	E	Methionine synthase	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	-
TLS3_k127_5864741_1	1123023.JIAI01000002_gene4571	5.047e-79	280.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4EF7B@85010|Pseudonocardiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE
TLS3_k127_5871541_0	1120948.KB903229_gene5187	1.293e-152	498.0	COG0515@1|root,COG0515@2|Bacteria,2IAZC@201174|Actinobacteria,4DXAZ@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TLS3_k127_5871541_1	1278078.G419_09936	9.028e-28	124.0	COG3266@1|root,COG3266@2|Bacteria,2GP1Z@201174|Actinobacteria,4FVEE@85025|Nocardiaceae	201174|Actinobacteria	S	Type VII secretion system ESX-1, transport TM domain B	eccB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	T7SS_ESX1_EccB
TLS3_k127_5878994_6	1120948.KB903240_gene3857	3.751e-82	282.0	COG0791@1|root,COG0791@2|Bacteria,2GKHE@201174|Actinobacteria,4DYBK@85010|Pseudonocardiales	201174|Actinobacteria	M	NlpC/P60 family	rpfI	GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0008150,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030312,GO:0040007,GO:0044464,GO:0061783,GO:0071944	-	ko:K21473,ko:K21474	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
TLS3_k127_5878994_0	1120948.KB903240_gene3856	1.027e-192	607.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4DXJG@85010|Pseudonocardiales	201174|Actinobacteria	S	associated with various cellular activities	moxR1	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
TLS3_k127_5878994_2	1120948.KB903240_gene3855	8.172e-138	463.0	COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4E03G@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
TLS3_k127_5878994_5	1120948.KB903240_gene3854	4.219e-117	395.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4DYPB@85010|Pseudonocardiales	201174|Actinobacteria	S	von Willebrand factor, type A	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
TLS3_k127_5878994_4	1120948.KB903240_gene3853	2.695e-126	407.0	COG1028@1|root,COG1028@2|Bacteria,2GK6C@201174|Actinobacteria,4DY8Q@85010|Pseudonocardiales	201174|Actinobacteria	IQ	reductase	fabG1	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0018454,GO:0019752,GO:0030497,GO:0032787,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046459,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070402,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059,ko:K11610	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_5878994_3	1120948.KB903240_gene3852	1.233e-135	436.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria,4DZIM@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	inhA	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_5878994_7	1206735.BAGG01000061_gene2557	5.063e-81	299.0	COG0657@1|root,COG0657@2|Bacteria,2I3E3@201174|Actinobacteria,4G87Z@85025|Nocardiaceae	201174|Actinobacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5878994_1	1120948.KB903240_gene3850	3.619e-192	605.0	COG0276@1|root,COG0276@2|Bacteria,2GJTQ@201174|Actinobacteria,4DZFZ@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
TLS3_k127_5878994_8	469371.Tbis_2162	8.488e-07	61.0	COG0491@1|root,COG0491@2|Bacteria,2IB2K@201174|Actinobacteria,4DZDI@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
TLS3_k127_588192_3	1035195.HMPREF9997_01194	1.516e-05	49.0	COG2145@1|root,COG2145@2|Bacteria,2IC73@201174|Actinobacteria,22KQU@1653|Corynebacteriaceae	201174|Actinobacteria	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
TLS3_k127_588192_1	266940.Krad_0853	7.308e-46	176.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria	201174|Actinobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
TLS3_k127_588192_0	1120948.KB903224_gene289	1.315e-129	427.0	COG3191@1|root,COG3191@2|Bacteria,2GJKQ@201174|Actinobacteria,4DY61@85010|Pseudonocardiales	201174|Actinobacteria	EQ	PFAM Peptidase family S58	dmpA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
TLS3_k127_588192_2	1210045.ALNP01000002_gene4138	2.516e-23	104.0	COG2207@1|root,COG2207@2|Bacteria,2GWDZ@201174|Actinobacteria	201174|Actinobacteria	K	Arac family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_5883591_0	1120948.KB903245_gene3453	0.0	1259.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria,4DXG4@85010|Pseudonocardiales	201174|Actinobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
TLS3_k127_5883591_1	1298880.AUEV01000004_gene1973	8.921e-52	196.0	COG1309@1|root,COG1309@2|Bacteria,2IP3P@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_5883591_2	1298880.AUEV01000004_gene1972	1.686e-25	110.0	COG0654@1|root,COG0654@2|Bacteria,2GK88@201174|Actinobacteria	201174|Actinobacteria	CH	PFAM monooxygenase FAD-binding	-	-	-	ko:K16037	ko01051,ko01052,ko01130,map01051,map01052,map01130	-	R09855	RC02841	ko00000,ko00001	-	-	-	FAD_binding_3
TLS3_k127_5885988_8	1120948.KB903240_gene3914	1.418e-57	231.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4DZM2@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TLS3_k127_5885988_3	1120948.KB903240_gene3915	5.686e-107	354.0	COG4279@1|root,COG4279@2|Bacteria,2GIYW@201174|Actinobacteria,4E233@85010|Pseudonocardiales	201174|Actinobacteria	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
TLS3_k127_5885988_0	1120948.KB903240_gene3916	0.0	1162.0	COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,4DX3H@85010|Pseudonocardiales	201174|Actinobacteria	L	SNF2 family N-terminal domain	helZ	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
TLS3_k127_5885988_9	1120948.KB903240_gene3917	5.907e-42	164.0	COG2146@1|root,COG2146@2|Bacteria,2IKSY@201174|Actinobacteria,4E5GP@85010|Pseudonocardiales	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	Rieske
TLS3_k127_5885988_4	1120948.KB903240_gene3918	7.238e-104	359.0	COG1011@1|root,COG1011@2|Bacteria,2IJA3@201174|Actinobacteria,4E48T@85010|Pseudonocardiales	201174|Actinobacteria	S	Hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	-
TLS3_k127_5885988_2	1120948.KB903240_gene3919	1.131e-143	472.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4DXYI@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
TLS3_k127_5885988_7	1120948.KB903240_gene3920	3.601e-63	233.0	2E71H@1|root,331K6@2|Bacteria,2IR72@201174|Actinobacteria,4E58E@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial PH domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	bPH_6
TLS3_k127_5885988_6	1120948.KB903240_gene3921	3.01e-69	239.0	COG0054@1|root,COG0054@2|Bacteria,2II1Z@201174|Actinobacteria,4E30Z@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0040007,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
TLS3_k127_5885988_1	1120948.KB903240_gene3922	1.509e-236	747.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,4DXCJ@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	GO:0005575,GO:0005576,GO:0008150,GO:0040007	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1415	DHBP_synthase,GTP_cyclohydro2
TLS3_k127_5885988_5	1120948.KB903240_gene3923	2.468e-88	295.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4E2BN@85010|Pseudonocardiales	201174|Actinobacteria	H	Riboflavin synthase	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
TLS3_k127_5889308_7	1120934.KB894425_gene1194	2.169e-26	111.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4DX5K@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
TLS3_k127_5889308_0	1120948.KB903228_gene4796	1.027e-133	437.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4DYMB@85010|Pseudonocardiales	201174|Actinobacteria	K	RNA polymerase sigma factor, sigma-70 family	sigF	GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS3_k127_5889308_4	1120948.KB903228_gene4797	1.039e-54	198.0	COG2172@1|root,COG2172@2|Bacteria,2IFG9@201174|Actinobacteria,4E67J@85010|Pseudonocardiales	201174|Actinobacteria	T	anti-sigma regulatory factor	rsbW	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
TLS3_k127_5889308_6	1120948.KB903228_gene4798	1.172e-48	178.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria,4E6KB@85010|Pseudonocardiales	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
TLS3_k127_5889308_5	1120948.KB903228_gene4799	3.465e-52	191.0	2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria,4E5Y7@85010|Pseudonocardiales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB3	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
TLS3_k127_5889308_3	1120948.KB903228_gene4800	3.212e-64	232.0	291ZT@1|root,2ZPJ4@2|Bacteria,2GR7R@201174|Actinobacteria,4E2RM@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2587)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2587
TLS3_k127_5889308_2	1120948.KB903228_gene4801	2.216e-64	229.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
TLS3_k127_5889308_1	1120948.KB903228_gene4802	6.802e-94	314.0	COG3569@1|root,COG3569@2|Bacteria,2GJTH@201174|Actinobacteria,4E1SD@85010|Pseudonocardiales	201174|Actinobacteria	G	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
TLS3_k127_5894026_2	2074.JNYD01000001_gene5985	5.25e-51	197.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4DXU0@85010|Pseudonocardiales	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
TLS3_k127_5894026_0	1120948.KB903240_gene3912	0.0	1142.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4DZ3F@85010|Pseudonocardiales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
TLS3_k127_5894026_1	1120948.KB903240_gene3914	2.636e-54	192.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4DZM2@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TLS3_k127_5932158_5	1120948.KB903217_gene1007	5.422e-21	91.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria	201174|Actinobacteria	IQ	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
TLS3_k127_5932158_4	1120948.KB903217_gene1008	1.892e-30	132.0	COG5658@1|root,COG5658@2|Bacteria	2|Bacteria	S	integral membrane protein	sdpI	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
TLS3_k127_5932158_0	1120948.KB903217_gene1009	0.0	1646.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4DYSA@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
TLS3_k127_5932158_1	1120948.KB903217_gene1011	2.091e-206	664.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4DYY3@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Myo-inositol-1-phosphate synthase	ino1	GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
TLS3_k127_5932158_2	1120948.KB903217_gene1012	7.008e-85	287.0	COG1695@1|root,COG1695@2|Bacteria,2GMJM@201174|Actinobacteria,4E1NG@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
TLS3_k127_5932158_3	1120948.KB903217_gene1013	2.564e-56	199.0	2CQNK@1|root,32SMG@2|Bacteria,2IIJ7@201174|Actinobacteria,4E3ED@85010|Pseudonocardiales	201174|Actinobacteria	S	Family of unknown function (DUF5318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5318
TLS3_k127_5938968_2	1120948.KB903219_gene679	3.065e-109	363.0	COG1266@1|root,COG1266@2|Bacteria,2GK11@201174|Actinobacteria,4DY1I@85010|Pseudonocardiales	201174|Actinobacteria	S	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
TLS3_k127_5938968_1	675635.Psed_0160	5.711e-132	441.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4E319@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
TLS3_k127_5938968_0	1120948.KB903219_gene678	7.602e-170	549.0	COG2235@1|root,COG2235@2|Bacteria,2GJTR@201174|Actinobacteria,4DYHX@85010|Pseudonocardiales	201174|Actinobacteria	E	Arginine deiminase	arcA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
TLS3_k127_5939392_0	1120948.KB903247_gene4500	5.837e-77	263.0	COG2755@1|root,COG2755@2|Bacteria,2GR6W@201174|Actinobacteria,4DZQ1@85010|Pseudonocardiales	201174|Actinobacteria	E	O-octanoyltransferase activity	octT	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008374,GO:0009987,GO:0016020,GO:0016043,GO:0016414,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0022607,GO:0040007,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051262,GO:0065003,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS3_k127_5939392_3	1123024.AUII01000008_gene1833	5.326e-11	73.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4E4AU@85010|Pseudonocardiales	201174|Actinobacteria	L	Competence protein ComEA	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
TLS3_k127_5939392_2	2074.JNYD01000006_gene1703	3.764e-45	167.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4E4AU@85010|Pseudonocardiales	201174|Actinobacteria	L	Competence protein ComEA	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
TLS3_k127_5939392_1	1120948.KB903247_gene4502	2.45e-66	241.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4DXGV@85010|Pseudonocardiales	201174|Actinobacteria	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
TLS3_k127_5942341_0	1120948.KB903232_gene4674	1.933e-50	188.0	COG1215@1|root,COG1215@2|Bacteria,2IHNF@201174|Actinobacteria,4E60K@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
TLS3_k127_5942341_1	1123024.AUII01000010_gene691	2.069e-39	156.0	COG0590@1|root,COG0590@2|Bacteria,2II3Z@201174|Actinobacteria,4E48Z@85010|Pseudonocardiales	201174|Actinobacteria	FJ	PFAM Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	-	-	-	-	-	-	-	-	-	-	MafB19-deam,dCMP_cyt_deam_1
TLS3_k127_5942433_6	266940.Krad_3085	3.349e-22	96.0	COG4329@1|root,COG4329@2|Bacteria,2IIU1@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2243
TLS3_k127_5942433_5	266940.Krad_3086	8.364e-44	173.0	COG3336@1|root,COG3336@2|Bacteria,2GVIH@201174|Actinobacteria	201174|Actinobacteria	S	Cytochrome C oxidase caa3-type, assembly factor CtaG-related	-	-	-	ko:K02351	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
TLS3_k127_5942433_0	479431.Namu_4795	2.838e-244	770.0	COG3961@1|root,COG3961@2|Bacteria,2GWS8@201174|Actinobacteria,4EU8V@85013|Frankiales	201174|Actinobacteria	C	Belongs to the TPP enzyme family	pdc	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0044464,GO:0071944	4.1.1.74	ko:K04103,ko:K21431	ko00380,ko01100,map00380,map01100	-	R01974	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TLS3_k127_5942433_1	2074.JNYD01000026_gene632	8.245e-166	545.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZWD@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_5942433_2	1120948.KB903222_gene570	2.076e-117	389.0	COG2313@1|root,COG2313@2|Bacteria,2GK19@201174|Actinobacteria,4DZU4@85010|Pseudonocardiales	201174|Actinobacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
TLS3_k127_5942433_4	1120948.KB903217_gene875	1.344e-68	249.0	COG3707@1|root,COG3707@2|Bacteria,2IISX@201174|Actinobacteria,4EERV@85010|Pseudonocardiales	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
TLS3_k127_5942433_7	1120948.KB903243_gene2615	3.762e-18	88.0	COG2114@1|root,COG2114@2|Bacteria,2I900@201174|Actinobacteria,4E4WE@85010|Pseudonocardiales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1647	Guanylate_cyc
TLS3_k127_5942433_3	1120948.KB903243_gene2615	2.99e-83	281.0	COG2114@1|root,COG2114@2|Bacteria,2I900@201174|Actinobacteria,4E4WE@85010|Pseudonocardiales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1647	Guanylate_cyc
TLS3_k127_5946155_0	1120948.KB903217_gene1496	1.132e-163	529.0	COG3243@1|root,COG3243@2|Bacteria,2GP7I@201174|Actinobacteria,4DY42@85010|Pseudonocardiales	201174|Actinobacteria	I	synthetase	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,PHB_depo_C
TLS3_k127_5963388_9	1120948.KB903224_gene293	8.294e-08	59.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4DZTZ@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
TLS3_k127_5963388_3	1120948.KB903224_gene294	9.749e-101	329.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4E1KZ@85010|Pseudonocardiales	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
TLS3_k127_5963388_6	1120948.KB903224_gene295	2.381e-78	273.0	COG2258@1|root,COG2258@2|Bacteria,2INTD@201174|Actinobacteria,4E1JX@85010|Pseudonocardiales	201174|Actinobacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,FAD_binding_6,Fer2,MOSC,NAD_binding_1
TLS3_k127_5963388_1	1120948.KB903224_gene296	3.794e-199	635.0	COG1216@1|root,COG1216@2|Bacteria,2I3S5@201174|Actinobacteria,4DZIU@85010|Pseudonocardiales	201174|Actinobacteria	S	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_5963388_7	1120949.KB903295_gene2178	5.88e-42	171.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria,4DE3N@85008|Micromonosporales	201174|Actinobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
TLS3_k127_5963388_4	1120948.KB903224_gene297	1.564e-86	297.0	COG1402@1|root,COG1402@2|Bacteria,2HCRK@201174|Actinobacteria,4E4MF@85010|Pseudonocardiales	201174|Actinobacteria	S	Creatinine amidohydrolase	mftE	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
TLS3_k127_5963388_0	1120948.KB903224_gene299	3.828e-204	661.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4E0V1@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	FAD_oxidored,Oxidored_FMN,Pyr_redox_2
TLS3_k127_5963388_2	1120948.KB903224_gene300	1.283e-158	520.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GMB6@201174|Actinobacteria,4E27M@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	NAD_binding_8,Oxidored_FMN,Pyr_redox,Pyr_redox_2
TLS3_k127_5963388_8	443218.AS9A_1540	3.651e-38	153.0	COG4758@1|root,COG4758@2|Bacteria,2I8FE@201174|Actinobacteria,232FC@1762|Mycobacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
TLS3_k127_5963388_5	2074.JNYD01000037_gene5089	5.165e-79	274.0	COG3918@1|root,COG3918@2|Bacteria,2I80W@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_5980624_3	1120948.KB903246_gene3402	4.271e-06	59.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,4DZKD@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM MazG family protein	mazG	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
TLS3_k127_5980624_2	1120948.KB903246_gene3403	1.747e-68	246.0	2F0CU@1|root,33TFY@2|Bacteria,2II7K@201174|Actinobacteria,4E40X@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3
TLS3_k127_5980624_0	345341.KUTG_04399	0.0	1325.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4DXZU@85010|Pseudonocardiales	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
TLS3_k127_5980624_1	1120948.KB903243_gene2567	9.325e-172	560.0	COG2133@1|root,COG2133@2|Bacteria,2GISM@201174|Actinobacteria,4DXUN@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Glucose Sorbosone dehydrogenase	gcd	-	-	-	-	-	-	-	-	-	-	-	GSDH
TLS3_k127_6016964_3	208439.AJAP_15780	2.941e-31	141.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4E2ZP@85010|Pseudonocardiales	201174|Actinobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3,1.5.99.4	ko:K03519,ko:K19818	ko00760,ko01120,map00760,map01120	M00810	R02860,R07946,R11168	RC00589,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
TLS3_k127_6016964_1	994479.GL877881_gene6631	4.897e-244	783.0	COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria,4E1X3@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	MFS_1,MFS_2,MFS_4,Sugar_tr
TLS3_k127_6016964_0	1068978.AMETH_3949	7.085e-248	775.0	COG0654@1|root,COG0654@2|Bacteria,2GIZU@201174|Actinobacteria,4E1JY@85010|Pseudonocardiales	201174|Actinobacteria	CH	FAD binding domain	-	-	1.14.13.1,1.14.13.24	ko:K00480,ko:K22270	ko00362,ko00621,ko00624,ko00626,ko01100,ko01120,ko01220,map00362,map00621,map00624,map00626,map01100,map01120,map01220	-	R00818,R02589,R05632,R06915,R06936,R06939	RC00046,RC00389	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
TLS3_k127_6016964_2	591158.SSMG_03084	1.443e-65	228.0	COG1846@1|root,COG1846@2|Bacteria,2IB1S@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
TLS3_k127_6017402_4	1120948.KB903240_gene3894	6.684e-20	90.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4DXR6@85010|Pseudonocardiales	201174|Actinobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
TLS3_k127_6017402_1	1120948.KB903240_gene3895	5.089e-243	766.0	COG0166@1|root,COG0166@2|Bacteria,2HIP2@201174|Actinobacteria,4DYDN@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
TLS3_k127_6017402_0	1120948.KB903240_gene3896	1.005e-319	989.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4DY1R@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
TLS3_k127_6017402_2	1120948.KB903240_gene3897	1.714e-141	457.0	COG3429@1|root,COG3429@2|Bacteria,2GJ1H@201174|Actinobacteria,4E0XZ@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Glucose-6-phosphate dehydrogenase subunit	opcA	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
TLS3_k127_6017402_3	1120948.KB903240_gene3898	4.232e-98	341.0	COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria,4DXRG@85010|Pseudonocardiales	201174|Actinobacteria	G	6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
TLS3_k127_6036332_1	1957.JODX01000006_gene3836	2.451e-177	564.0	COG0438@1|root,COG0438@2|Bacteria,2GSQI@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
TLS3_k127_6036332_0	208439.AJAP_36870	9.389e-197	625.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,4E15T@85010|Pseudonocardiales	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	algD	-	1.1.1.132	ko:K00066	ko00051,ko00520,ko02020,map00051,map00520,map02020	-	R00880	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
TLS3_k127_6036332_3	290397.Adeh_2643	4.933e-44	175.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
TLS3_k127_6036332_2	1120948.KB903243_gene2637	3.555e-88	309.0	COG0726@1|root,COG0726@2|Bacteria,2I8IQ@201174|Actinobacteria,4EAMN@85010|Pseudonocardiales	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
TLS3_k127_6036332_4	1463934.JOCF01000001_gene6956	1.256e-35	138.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
TLS3_k127_6039387_2	1120948.KB903248_gene4340	1.439e-202	641.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,4E0F7@85010|Pseudonocardiales	201174|Actinobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
TLS3_k127_6039387_1	1120948.KB903248_gene4341	5.046e-267	826.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4DZEU@85010|Pseudonocardiales	201174|Actinobacteria	C	TIGRFAM Dihydrolipoamide dehydrogenase	pdhD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_6039387_0	1120948.KB903248_gene4342	9.617e-276	863.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4E04X@85010|Pseudonocardiales	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	sucB	GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008289,GO:0009405,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0030312,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0043177,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050662,GO:0050789,GO:0050794,GO:0051704,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
TLS3_k127_6039387_6	1120948.KB903248_gene4343	3.473e-146	469.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4DYE7@85010|Pseudonocardiales	201174|Actinobacteria	S	NAD- dependent epimerase dehydratase	-	GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0030312,GO:0031073,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0046906,GO:0048037,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901615,GO:1901616,GO:1902652	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
TLS3_k127_6039387_5	1120948.KB903248_gene4344	4.239e-170	561.0	COG1232@1|root,COG1232@2|Bacteria,2I3QR@201174|Actinobacteria,4DZ1J@85010|Pseudonocardiales	201174|Actinobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
TLS3_k127_6039387_8	1120948.KB903248_gene4345	8.299e-103	347.0	COG0321@1|root,COG0321@2|Bacteria,2GJIX@201174|Actinobacteria,4DXWW@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
TLS3_k127_6039387_4	1298880.AUEV01000010_gene2815	3.172e-173	562.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_6039387_7	1120948.KB903248_gene4348	1.595e-139	449.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4DXNN@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
TLS3_k127_6039387_3	1120948.KB903248_gene4349	2.796e-180	567.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4DZPM@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
TLS3_k127_6039564_2	1120948.KB903218_gene2085	9.894e-168	537.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4E0F3@85010|Pseudonocardiales	201174|Actinobacteria	G	PEP-utilising enzyme, mobile domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
TLS3_k127_6039564_1	1120948.KB903243_gene2383	0.0	1323.0	COG0376@1|root,COG0376@2|Bacteria,2GJFP@201174|Actinobacteria,4DYF0@85010|Pseudonocardiales	201174|Actinobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
TLS3_k127_6039564_7	479431.Namu_2946	5.728e-21	97.0	COG3670@1|root,COG3670@2|Bacteria,2GK7D@201174|Actinobacteria,4ESPY@85013|Frankiales	201174|Actinobacteria	C	dioxygenase	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
TLS3_k127_6039564_4	1120948.KB903225_gene5574	2.793e-114	377.0	COG0300@1|root,COG0300@2|Bacteria,2HFIR@201174|Actinobacteria,4ECGJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_6039564_0	1120948.KB903220_gene57	0.0	1337.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4E1QR@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
TLS3_k127_6039564_3	1120950.KB892758_gene6311	2.764e-124	404.0	COG0596@1|root,COG0596@2|Bacteria,2I97G@201174|Actinobacteria,4DWNP@85009|Propionibacteriales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
TLS3_k127_6039564_5	675635.Psed_1170	1.432e-90	306.0	COG3629@1|root,COG3629@2|Bacteria,2IBMM@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
TLS3_k127_6039564_8	675635.Psed_1169	8.26e-18	92.0	2ECI1@1|root,336G9@2|Bacteria,2GTD0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
TLS3_k127_6039564_9	1120948.KB903220_gene4	1.305e-13	71.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4DY4S@85010|Pseudonocardiales	201174|Actinobacteria	EQ	PFAM Hydantoinase oxoprolinase	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
TLS3_k127_6042842_0	446462.Amir_6071	0.0	1187.0	COG0058@1|root,COG0058@2|Bacteria,2GIVZ@201174|Actinobacteria,4DXQ9@85010|Pseudonocardiales	201174|Actinobacteria	G	phosphorylase	glgP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
TLS3_k127_6055664_2	1120948.KB903229_gene5300	1.496e-80	273.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZBV@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	fadD36	-	-	ko:K12429,ko:K18662	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_6055664_1	1120948.KB903244_gene2965	3.422e-106	366.0	COG1277@1|root,COG1277@2|Bacteria,2GP6D@201174|Actinobacteria,4E258@85010|Pseudonocardiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
TLS3_k127_6055664_0	1120948.KB903244_gene2964	2.407e-134	433.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria,4DZGR@85010|Pseudonocardiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
TLS3_k127_6057955_0	1120948.KB903219_gene732	2.697e-244	758.0	COG0562@1|root,COG0562@2|Bacteria,2GK2Z@201174|Actinobacteria,4DYDZ@85010|Pseudonocardiales	201174|Actinobacteria	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
TLS3_k127_6057955_1	2074.JNYD01000015_gene4575	4.592e-232	745.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4DY9E@85010|Pseudonocardiales	201174|Actinobacteria	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
TLS3_k127_6057955_2	2074.JNYD01000015_gene4576	9.411e-112	369.0	COG2197@1|root,COG2197@2|Bacteria,2IP1K@201174|Actinobacteria,4EF2M@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
TLS3_k127_6057955_3	1120948.KB903219_gene734	1.509e-25	107.0	COG0627@1|root,COG0627@2|Bacteria,2GP6Q@201174|Actinobacteria,4E0VI@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
TLS3_k127_6071098_7	1120948.KB903218_gene2171	1.667e-17	90.0	COG3145@1|root,COG3145@2|Bacteria,2GNBD@201174|Actinobacteria,4E0FZ@85010|Pseudonocardiales	201174|Actinobacteria	L	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
TLS3_k127_6071098_8	448385.sce7933	4.667e-16	81.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,42V8V@68525|delta/epsilon subdivisions,2WRKG@28221|Deltaproteobacteria,2Z0Y9@29|Myxococcales	28221|Deltaproteobacteria	C	acylphosphatase activity	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
TLS3_k127_6071098_2	1206744.BAGL01000050_gene966	7.641e-102	350.0	COG3214@1|root,COG3214@2|Bacteria,2I5MD@201174|Actinobacteria,4FW8Z@85025|Nocardiaceae	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
TLS3_k127_6071098_5	446462.Amir_0337	4.048e-42	173.0	COG3021@1|root,COG3021@2|Bacteria,2GKXC@201174|Actinobacteria,4DZ69@85010|Pseudonocardiales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_6071098_6	1120948.KB903248_gene4404	9.01e-29	130.0	COG0454@1|root,COG0456@2|Bacteria,2GK6K@201174|Actinobacteria,4E68V@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
TLS3_k127_6071098_1	1120948.KB903248_gene4405	2.226e-142	458.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4DZF4@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
TLS3_k127_6071098_4	1120948.KB903217_gene915	1.303e-59	213.0	COG2050@1|root,COG2050@2|Bacteria,2IJ48@201174|Actinobacteria,4E5BE@85010|Pseudonocardiales	201174|Actinobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
TLS3_k127_6071098_0	222534.KB893716_gene1844	2.54e-177	568.0	COG2133@1|root,COG2133@2|Bacteria,2GP8F@201174|Actinobacteria	201174|Actinobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
TLS3_k127_6071098_3	1120948.KB903244_gene3117	1.26e-65	228.0	COG3832@1|root,COG3832@2|Bacteria,2IQVQ@201174|Actinobacteria,4ECP8@85010|Pseudonocardiales	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_6073267_7	1089545.KB913037_gene6038	2.673e-58	203.0	COG3460@1|root,COG3460@2|Bacteria,2IKMJ@201174|Actinobacteria,4E4A8@85010|Pseudonocardiales	201174|Actinobacteria	Q	PFAM Phenylacetic acid degradation B	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
TLS3_k127_6073267_2	1120948.KB903218_gene2068	9.075e-137	441.0	COG3396@1|root,COG3396@2|Bacteria,2GJIU@201174|Actinobacteria,4DX3W@85010|Pseudonocardiales	201174|Actinobacteria	S	Phenylacetate-CoA oxygenase, PaaI subunit	paaI	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
TLS3_k127_6073267_5	994479.GL877878_gene1108	5.263e-63	234.0	COG2151@1|root,COG2151@2|Bacteria,2II4H@201174|Actinobacteria,4E3Q4@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
TLS3_k127_6073267_1	1120948.KB903218_gene2066	3.522e-164	532.0	COG1018@1|root,COG1018@2|Bacteria,2GKGS@201174|Actinobacteria,4DZF7@85010|Pseudonocardiales	201174|Actinobacteria	C	Phenylacetate-CoA oxygenase reductase, PaaK subunit	paaK	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
TLS3_k127_6073267_0	1120948.KB903218_gene2065	0.0	1147.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,2GMEG@201174|Actinobacteria,4E1I4@85010|Pseudonocardiales	201174|Actinobacteria	CI	TIGRFAM phenylacetic acid degradation protein paaN	paaZ	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,MaoC_dehydratas
TLS3_k127_6073267_8	1120948.KB903218_gene2064	6.555e-53	212.0	COG2050@1|root,COG2050@2|Bacteria,2IKWI@201174|Actinobacteria,4E4N0@85010|Pseudonocardiales	201174|Actinobacteria	Q	phenylacetic acid degradation protein PaaD	paaI	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
TLS3_k127_6073267_6	1323361.JPOC01000008_gene3448	3.397e-59	218.0	COG0346@1|root,COG0346@2|Bacteria,2IHQQ@201174|Actinobacteria,4G2SZ@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_6073267_10	1323361.JPOC01000008_gene3447	2.535e-40	151.0	COG0640@1|root,COG0640@2|Bacteria,2GNW2@201174|Actinobacteria,4G39U@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
TLS3_k127_6073267_9	1120948.KB903246_gene3244	5.183e-45	176.0	COG1917@1|root,COG1917@2|Bacteria,2I3J0@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_6073267_3	1120948.KB903225_gene5508	9.776e-106	350.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4E8M8@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.149	ko:K08299	-	-	R10675	RC01095	ko00000,ko01000	-	-	-	ECH_1
TLS3_k127_6073267_4	1283287.KB822577_gene3345	1.374e-73	262.0	COG2860@1|root,COG2860@2|Bacteria,2GMI4@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0126
TLS3_k127_6073267_11	258052.JNYV01000002_gene1107	8.236e-18	94.0	COG1846@1|root,COG1846@2|Bacteria,2IIP0@201174|Actinobacteria	201174|Actinobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
TLS3_k127_6073267_12	543632.JOJL01000022_gene856	0.0002084	52.0	2E5PW@1|root,330EJ@2|Bacteria,2GRTF@201174|Actinobacteria,4DGJX@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3817
TLS3_k127_6075074_1	1120948.KB903229_gene5208	1.365e-70	266.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria,4E796@85010|Pseudonocardiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
TLS3_k127_6075074_0	1120948.KB903229_gene5209	1.283e-205	651.0	COG1020@1|root,COG1020@2|Bacteria,2GKGU@201174|Actinobacteria,4E2Q6@85010|Pseudonocardiales	201174|Actinobacteria	Q	Wax ester synthase-like Acyl-CoA acyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
TLS3_k127_6077212_12	33876.JNXY01000060_gene9504	4.671e-17	82.0	COG0212@1|root,COG0212@2|Bacteria,2GM4X@201174|Actinobacteria,4DET6@85008|Micromonosporales	201174|Actinobacteria	H	5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
TLS3_k127_6077212_10	1120948.KB903240_gene3729	9.458e-24	113.0	2DFGR@1|root,2ZRSG@2|Bacteria,2GX9P@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6077212_6	1032480.MLP_47110	1.725e-63	224.0	COG1309@1|root,COG1309@2|Bacteria,2IJP2@201174|Actinobacteria,4DSE4@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_6077212_5	710686.Mycsm_01123	7.308e-66	233.0	COG1595@1|root,COG1595@2|Bacteria,2GM8T@201174|Actinobacteria,2336F@1762|Mycobacteriaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigD	GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS3_k127_6077212_3	1120948.KB903240_gene3748	2.441e-212	678.0	COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria,4DXZT@85010|Pseudonocardiales	201174|Actinobacteria	M	Cyclopropane-fatty-acyl-phospholipid synthase	cfa	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
TLS3_k127_6077212_0	1120948.KB903240_gene3749	6.01e-220	691.0	COG0277@1|root,COG0277@2|Bacteria,2GKQR@201174|Actinobacteria,4DYBE@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
TLS3_k127_6077212_11	2074.JNYD01000003_gene3586	6.194e-21	94.0	2DS3D@1|root,33EC4@2|Bacteria,2GXNR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6077212_9	2074.JNYD01000003_gene3585	1.891e-32	127.0	2E6FA@1|root,3312Q@2|Bacteria,2GUWJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6077212_2	1123024.AUII01000006_gene4729	1.319e-212	669.0	COG0526@1|root,COG0526@2|Bacteria,2IET9@201174|Actinobacteria,4EASN@85010|Pseudonocardiales	201174|Actinobacteria	CO	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6077212_7	1120948.KB903229_gene5045	5.363e-57	204.0	COG3609@1|root,COG3609@2|Bacteria,2INEB@201174|Actinobacteria,4EB94@85010|Pseudonocardiales	201174|Actinobacteria	K	addiction module antidote protein, CC2985 family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6077212_4	1120948.KB903229_gene5044	2.315e-75	290.0	COG3509@1|root,COG3509@2|Bacteria,2GMTA@201174|Actinobacteria,4DZE7@85010|Pseudonocardiales	201174|Actinobacteria	Q	Esterase PHB depolymerase	phaZ1	-	3.1.1.72	ko:K05972	-	-	-	-	ko00000,ko01000	-	-	-	CBM_2,Esterase_phd,RicinB_lectin_2,Ricin_B_lectin
TLS3_k127_6077212_1	1120948.KB903240_gene3750	1.513e-216	680.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4DXSI@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase LigD, polymerase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
TLS3_k127_6089305_5	1003195.SCAT_5701	2.412e-13	77.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_6089305_0	543632.JOJL01000046_gene3405	1.526e-32	138.0	COG1714@1|root,COG1714@2|Bacteria,2HWNZ@201174|Actinobacteria,4DJRD@85008|Micromonosporales	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
TLS3_k127_6089305_2	1123024.AUII01000004_gene1528	1.402e-25	117.0	COG2524@1|root,COG2524@2|Bacteria,2I73D@201174|Actinobacteria,4EE6Y@85010|Pseudonocardiales	201174|Actinobacteria	K	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
TLS3_k127_6089305_3	1123023.JIAI01000033_gene4193	2.103e-25	112.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria,4E7CJ@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_6089305_6	2002.JOEQ01000013_gene5486	0.0001006	53.0	COG0517@1|root,COG0517@2|Bacteria,2GQ8D@201174|Actinobacteria,4EKSV@85012|Streptosporangiales	201174|Actinobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
TLS3_k127_6089305_1	675635.Psed_4841	1.394e-27	128.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4E2RP@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_6089305_4	1123023.JIAI01000028_gene4525	1.077e-19	96.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria,4E6RZ@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_6089842_0	1120948.KB903246_gene3193	2.915e-133	434.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4E2IJ@85010|Pseudonocardiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
TLS3_k127_6089842_1	1120948.KB903246_gene3194	4.837e-75	264.0	COG3963@1|root,COG3963@2|Bacteria,2I93P@201174|Actinobacteria,4E3IH@85010|Pseudonocardiales	201174|Actinobacteria	I	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_6089842_2	1120948.KB903246_gene3195	7.182e-33	137.0	COG0762@1|root,COG0762@2|Bacteria,2GQI1@201174|Actinobacteria,4E5G2@85010|Pseudonocardiales	201174|Actinobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
TLS3_k127_6089842_4	234267.Acid_6657	9.607e-11	71.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TLS3_k127_6089842_3	471857.Svir_00940	6.429e-31	136.0	COG3502@1|root,COG3502@2|Bacteria,2GQK6@201174|Actinobacteria,4E5Y3@85010|Pseudonocardiales	201174|Actinobacteria	K	Protein of unknown function (DUF952)	-	-	-	-	-	-	-	-	-	-	-	-	DUF952
TLS3_k127_6089842_5	1121106.JQKB01000007_gene962	2.032e-05	55.0	COG1893@1|root,COG1893@2|Bacteria,1MVZ1@1224|Proteobacteria,2TRJN@28211|Alphaproteobacteria,2JR4P@204441|Rhodospirillales	204441|Rhodospirillales	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	-	-	-	-	-	-	-	-	-	-	ApbA,ApbA_C
TLS3_k127_6095078_0	1120948.KB903244_gene3071	1.269e-263	814.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4DXNY@85010|Pseudonocardiales	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
TLS3_k127_6095078_4	1120948.KB903244_gene3070	7.97e-47	170.0	COG1550@1|root,COG1550@2|Bacteria,2IQW4@201174|Actinobacteria,4E5G9@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
TLS3_k127_6095078_3	1120948.KB903244_gene3069	5.657e-57	210.0	COG0858@1|root,COG0858@2|Bacteria,2IKXP@201174|Actinobacteria,4E3NQ@85010|Pseudonocardiales	201174|Actinobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
TLS3_k127_6095078_2	405948.SACE_5923	1.879e-113	382.0	COG0618@1|root,COG0618@2|Bacteria,2GN9Z@201174|Actinobacteria,4DZJ8@85010|Pseudonocardiales	201174|Actinobacteria	S	DHH family	nrnA	GO:0008150,GO:0040007	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
TLS3_k127_6095078_1	1120948.KB903244_gene3068	1.268e-150	502.0	COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria,4DZN6@85010|Pseudonocardiales	201174|Actinobacteria	V	efflux protein, MATE family	dinF	-	-	-	-	-	-	-	-	-	-	-	MatE
TLS3_k127_6116666_12	1120948.KB903243_gene2540	5.512e-32	138.0	COG0477@1|root,COG0477@2|Bacteria,2GKFJ@201174|Actinobacteria,4DY6H@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	entS_1	-	-	-	-	-	-	-	-	-	-	-	MFS_3
TLS3_k127_6116666_6	1120948.KB903243_gene2542	7.012e-93	316.0	COG0259@1|root,COG0259@2|Bacteria,2GJCR@201174|Actinobacteria,4DZ7E@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0010181,GO:0016491,GO:0016614,GO:0016899,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032553,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2607	PNP_phzG_C,Putative_PNPOx
TLS3_k127_6116666_4	1137271.AZUM01000002_gene2657	2.608e-160	515.0	COG0372@1|root,COG0372@2|Bacteria,2GKST@201174|Actinobacteria,4DYMH@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the citrate synthase family	citA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
TLS3_k127_6116666_9	1120948.KB903240_gene3783	1.17e-69	264.0	COG2852@1|root,COG2852@2|Bacteria,2GKCY@201174|Actinobacteria,4EB4D@85010|Pseudonocardiales	201174|Actinobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4,DUF559
TLS3_k127_6116666_2	1268303.RHODMAR_4349	1.893e-183	601.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4FY3I@85025|Nocardiaceae	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
TLS3_k127_6116666_7	1120948.KB903243_gene2544	3.049e-88	306.0	28PUQ@1|root,2ZCFK@2|Bacteria,2GNQM@201174|Actinobacteria,4E0Q6@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3071)	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	DUF3071
TLS3_k127_6116666_10	1120948.KB903243_gene2545	1e-43	178.0	2EVP5@1|root,33P34@2|Bacteria,2IQ93@201174|Actinobacteria,4E3V7@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2537)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2537
TLS3_k127_6116666_5	1120948.KB903243_gene2546	1.272e-108	365.0	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,4DXY0@85010|Pseudonocardiales	201174|Actinobacteria	J	PFAM SpoU rRNA Methylase family	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
TLS3_k127_6116666_8	1120948.KB903243_gene2547	1.21e-83	282.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4DXJH@85010|Pseudonocardiales	201174|Actinobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
TLS3_k127_6116666_0	1120948.KB903243_gene2548	8.532e-227	715.0	COG2170@1|root,COG2170@2|Bacteria,2GKCT@201174|Actinobacteria,4E10A@85010|Pseudonocardiales	201174|Actinobacteria	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
TLS3_k127_6116666_3	1120948.KB903243_gene2549	3.245e-179	570.0	COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria,4EF9U@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
TLS3_k127_6116666_14	1120948.KB903243_gene2550	7.774e-30	119.0	COG3360@1|root,COG3360@2|Bacteria,2IQ6Z@201174|Actinobacteria,4E6TZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
TLS3_k127_6116666_1	1120948.KB903243_gene2551	2.562e-223	706.0	COG2041@1|root,COG2041@2|Bacteria,2GIZH@201174|Actinobacteria,4DZWR@85010|Pseudonocardiales	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
TLS3_k127_6116666_13	330084.JNYZ01000003_gene2090	1.095e-31	143.0	2E339@1|root,32Y3E@2|Bacteria,2IJ6D@201174|Actinobacteria,4E6QD@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6116666_11	222534.KB893772_gene4541	1.525e-42	161.0	COG0500@1|root,COG2226@2|Bacteria,2IHWE@201174|Actinobacteria	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_6125795_2	1120948.KB903229_gene5010	5.029e-46	172.0	COG1192@1|root,COG1192@2|Bacteria,2I44R@201174|Actinobacteria,4EFCD@85010|Pseudonocardiales	201174|Actinobacteria	D	Involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
TLS3_k127_6125795_0	1120948.KB903229_gene5009	1.648e-93	317.0	COG3177@1|root,COG3177@2|Bacteria,2GIT8@201174|Actinobacteria,4E0E2@85010|Pseudonocardiales	201174|Actinobacteria	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
TLS3_k127_6125795_1	1120948.KB903220_gene148	5.877e-82	284.0	COG1584@1|root,COG1584@2|Bacteria,2IIIX@201174|Actinobacteria,4E5A7@85010|Pseudonocardiales	201174|Actinobacteria	S	GPR1/FUN34/yaaH family	-	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
TLS3_k127_6131865_0	1120948.KB903240_gene3781	1.01e-180	571.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4DZ1H@85010|Pseudonocardiales	201174|Actinobacteria	O	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
TLS3_k127_6131865_1	1120948.KB903240_gene3782	1.396e-150	480.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,4DX8Q@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	trmI	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
TLS3_k127_6131865_2	1429046.RR21198_4704	3.204e-73	255.0	COG2887@1|root,COG2887@2|Bacteria,2GJC5@201174|Actinobacteria,4FV95@85025|Nocardiaceae	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	recB	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
TLS3_k127_6132408_3	1120948.KB903224_gene371	1.099e-37	145.0	COG3396@1|root,COG3396@2|Bacteria,2GMBI@201174|Actinobacteria,4DYYP@85010|Pseudonocardiales	201174|Actinobacteria	S	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
TLS3_k127_6132408_1	1120948.KB903224_gene370	1.309e-82	280.0	COG1309@1|root,COG1309@2|Bacteria,2IIZX@201174|Actinobacteria,4E5QV@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_6132408_2	1120948.KB903224_gene369	1.555e-60	217.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
TLS3_k127_6132408_0	1120948.KB903224_gene368	3.479e-86	293.0	2AVV0@1|root,31MNQ@2|Bacteria,2GJKP@201174|Actinobacteria,4E2PK@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3159
TLS3_k127_6132408_4	1120948.KB903224_gene364	1.512e-23	108.0	2E39G@1|root,32Y91@2|Bacteria,2GQNT@201174|Actinobacteria,4E705@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6138853_1	2074.JNYD01000009_gene5321	1.098e-41	156.0	COG4803@1|root,COG4803@2|Bacteria,2IHYU@201174|Actinobacteria,4E3RP@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
TLS3_k127_6138853_2	675635.Psed_4255	5.729e-15	83.0	28WQQ@1|root,2ZIQE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6138853_0	1380356.JNIK01000015_gene2375	1.506e-56	206.0	COG2909@1|root,COG2909@2|Bacteria,2IDM6@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_22,GerE
TLS3_k127_6151252_4	1449976.KALB_5708	1.372e-37	161.0	COG1309@1|root,COG1309@2|Bacteria,2IPVA@201174|Actinobacteria,4EEZ0@85010|Pseudonocardiales	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
TLS3_k127_6151252_3	1449976.KALB_5709	4.611e-60	227.0	COG0596@1|root,COG0596@2|Bacteria,2GK43@201174|Actinobacteria,4DYFZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
TLS3_k127_6151252_6	405948.SACE_1411	2.248e-26	124.0	2DHBJ@1|root,32U91@2|Bacteria,2GPPB@201174|Actinobacteria,4E75A@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6151252_0	1120948.KB903243_gene2295	6.135e-166	550.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4E058@85010|Pseudonocardiales	201174|Actinobacteria	JM	PFAM Nucleotidyl transferase	manC	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
TLS3_k127_6151252_1	1120948.KB903243_gene2294	1.196e-144	468.0	COG0122@1|root,COG0122@2|Bacteria,2GP69@201174|Actinobacteria,4DXEY@85010|Pseudonocardiales	201174|Actinobacteria	L	3-methyladenine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6151252_2	1120948.KB903243_gene2291	1.207e-69	244.0	COG1051@1|root,COG1051@2|Bacteria,2I2SX@201174|Actinobacteria,4EFF3@85010|Pseudonocardiales	201174|Actinobacteria	F	PFAM NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_6151252_5	1463825.JNXC01000035_gene2595	3.447e-35	135.0	COG0778@1|root,COG1478@1|root,COG0778@2|Bacteria,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,4DX67@85010|Pseudonocardiales	201174|Actinobacteria	C	F420-0 Gamma-glutamyl ligase	fbiB	GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase,Nitroreductase
TLS3_k127_6151733_6	1120948.KB903240_gene4075	5.694e-45	176.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4E1CX@85010|Pseudonocardiales	201174|Actinobacteria	E	ABC-type branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
TLS3_k127_6151733_1	1120948.KB903240_gene4076	1.575e-95	317.0	COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,4DYAM@85010|Pseudonocardiales	201174|Actinobacteria	T	Response regulator receiver	pdtaR	GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
TLS3_k127_6151733_4	1120949.KB903328_gene8978	1.006e-51	188.0	COG1902@1|root,COG1902@2|Bacteria,2IHUT@201174|Actinobacteria	201174|Actinobacteria	C	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
TLS3_k127_6151733_12	40571.JOEA01000008_gene2697	7.975e-05	52.0	COG1961@1|root,COG1961@2|Bacteria,2GNGI@201174|Actinobacteria,4E13I@85010|Pseudonocardiales	201174|Actinobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
TLS3_k127_6151733_2	67267.JNXT01000018_gene7879	1.776e-93	323.0	COG0477@1|root,COG2814@2|Bacteria,2HBIW@201174|Actinobacteria	201174|Actinobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_6151733_8	935839.JAGJ01000024_gene2472	3.715e-29	119.0	2E35Q@1|root,32Y5M@2|Bacteria,2GS2Q@201174|Actinobacteria,4F5YC@85017|Promicromonosporaceae	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
TLS3_k127_6151733_5	1172181.KB911703_gene187	1.081e-51	187.0	COG4803@1|root,COG4803@2|Bacteria,2IIN1@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6151733_0	1120948.KB903222_gene556	3.801e-124	413.0	COG0628@1|root,COG0628@2|Bacteria,2GM01@201174|Actinobacteria,4DXSF@85010|Pseudonocardiales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS3_k127_6151733_3	675635.Psed_5992	1.266e-83	291.0	COG1295@1|root,COG1295@2|Bacteria,2HQRK@201174|Actinobacteria,4EBVK@85010|Pseudonocardiales	201174|Actinobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	-
TLS3_k127_6151733_7	710111.FraQA3DRAFT_4078	3.121e-42	163.0	2CK3K@1|root,32SBH@2|Bacteria,2IQJH@201174|Actinobacteria,4EW1Y@85013|Frankiales	201174|Actinobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
TLS3_k127_6151733_11	1150398.JIBJ01000005_gene3112	1.304e-05	49.0	COG0038@1|root,COG0038@2|Bacteria,2GJHP@201174|Actinobacteria	201174|Actinobacteria	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
TLS3_k127_6152413_6	1120948.KB903245_gene3722	6.356e-57	204.0	COG1898@1|root,COG1898@2|Bacteria,2GMW4@201174|Actinobacteria,4E0M8@85010|Pseudonocardiales	201174|Actinobacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase	rmlC	-	5.1.3.13	ko:K01790,ko:K16438	ko00404,ko00521,ko00523,ko01055,ko01130,map00404,map00521,map00523,map01055,map01130	M00793,M00798,M00799,M00800	R06433,R06514,R06628,R08934,R11046,R11138	RC01518,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
TLS3_k127_6152413_1	1120948.KB903245_gene3721	3.006e-202	639.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4DYNM@85010|Pseudonocardiales	201174|Actinobacteria	C	Malic enzyme	mez_1	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
TLS3_k127_6152413_0	345341.KUTG_06224	1.055e-203	667.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DXTJ@85010|Pseudonocardiales	201174|Actinobacteria	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
TLS3_k127_6152413_2	103733.JNYO01000006_gene1797	2.689e-141	458.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,4DYF4@85010|Pseudonocardiales	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
TLS3_k127_6152413_5	1120948.KB903245_gene3718	2.106e-67	252.0	COG1174@1|root,COG1174@2|Bacteria,2GMU0@201174|Actinobacteria,4DYJM@85010|Pseudonocardiales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	proW	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
TLS3_k127_6152413_4	1120948.KB903245_gene3717	4.62e-75	269.0	COG1174@1|root,COG1174@2|Bacteria,2GYTC@201174|Actinobacteria,4E1XU@85010|Pseudonocardiales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	proZ	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
TLS3_k127_6152413_3	1120948.KB903245_gene3716	2.156e-118	399.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4DZK6@85010|Pseudonocardiales	201174|Actinobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
TLS3_k127_6165452_1	1120948.KB903245_gene3538	3.126e-83	281.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4DYSM@85010|Pseudonocardiales	201174|Actinobacteria	E	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	ilvB	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030312,GO:0030976,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3003c	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TLS3_k127_6165452_2	1120948.KB903245_gene3539	9.152e-48	178.0	2EKMU@1|root,33EBJ@2|Bacteria,2GR8C@201174|Actinobacteria,4E5ZT@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial PH domain	cfp6	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	bPH_6
TLS3_k127_6165452_0	1120948.KB903245_gene3540	0.0	1106.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4DX86@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
TLS3_k127_6165452_3	653045.Strvi_1127	7.453e-47	172.0	COG1309@1|root,COG1309@2|Bacteria,2IBKZ@201174|Actinobacteria	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
TLS3_k127_6193342_0	1120948.KB903244_gene2936	1.719e-264	818.0	COG1249@1|root,COG1249@2|Bacteria,2GPG1@201174|Actinobacteria,4DXK3@85010|Pseudonocardiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	sthA	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_6193342_3	1003195.SCAT_3326	2.069e-110	369.0	COG3844@1|root,COG3844@2|Bacteria,2GMJQ@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
TLS3_k127_6193342_1	1120948.KB903244_gene2940	9.304e-144	482.0	COG1503@1|root,COG1503@2|Bacteria,2GNN3@201174|Actinobacteria,4E1R4@85010|Pseudonocardiales	201174|Actinobacteria	J	translation release factor activity	-	GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	-
TLS3_k127_6193342_2	1120948.KB903244_gene2948	1.342e-121	429.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4E29J@85010|Pseudonocardiales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
TLS3_k127_6193342_5	2074.JNYD01000001_gene5940	5.704e-42	159.0	2E8T5@1|root,3333Y@2|Bacteria,2IS1D@201174|Actinobacteria,4E7K2@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6193342_4	1120948.KB903244_gene2950	1.138e-62	226.0	COG1695@1|root,COG1695@2|Bacteria,2IFDN@201174|Actinobacteria,4E4AX@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_6193592_3	1120948.KB903243_gene2352	5.814e-49	175.0	COG0521@1|root,COG0521@2|Bacteria,2IACJ@201174|Actinobacteria,4E2MX@85010|Pseudonocardiales	201174|Actinobacteria	H	molybdenum cofactor	moaB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	MoCF_biosynth
TLS3_k127_6193592_4	1123024.AUII01000020_gene3194	1.315e-42	164.0	COG3745@1|root,COG3745@2|Bacteria,2GQJH@201174|Actinobacteria,4E5T3@85010|Pseudonocardiales	201174|Actinobacteria	U	PFAM SAF domain	-	-	-	-	-	-	-	-	-	-	-	-	ChapFlgA,RcpC,SAF
TLS3_k127_6193592_1	1120948.KB903243_gene2350	5.398e-105	364.0	COG0697@1|root,COG0697@2|Bacteria,2GRXH@201174|Actinobacteria,4E5AF@85010|Pseudonocardiales	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6193592_5	675635.Psed_0796	2.281e-24	108.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,4E5CR@85010|Pseudonocardiales	201174|Actinobacteria	S	regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
TLS3_k127_6193592_2	1120948.KB903243_gene2348	3.523e-65	232.0	COG0212@1|root,COG0212@2|Bacteria,2IKWR@201174|Actinobacteria,4E4KF@85010|Pseudonocardiales	201174|Actinobacteria	H	5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
TLS3_k127_6193592_0	1120948.KB903243_gene2347	2.794e-177	564.0	COG4284@1|root,COG4284@2|Bacteria,2I2G3@201174|Actinobacteria,4E9WY@85010|Pseudonocardiales	201174|Actinobacteria	G	UTP--glucose-1-phosphate uridylyltransferase	ugpA	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
TLS3_k127_6199639_4	1229780.BN381_140029	3.597e-07	53.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,3UWFT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_6199639_0	675635.Psed_5542	3.019e-196	651.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,2IEEA@201174|Actinobacteria,4E8EQ@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
TLS3_k127_6199639_1	1120948.KB903218_gene1991	5.315e-166	529.0	COG0500@1|root,COG0500@2|Bacteria,2I3GX@201174|Actinobacteria,4EE6R@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
TLS3_k127_6199639_2	512565.AMIS_18590	1.53e-125	426.0	COG0500@1|root,COG2226@2|Bacteria,2I3SA@201174|Actinobacteria,4DMSZ@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
TLS3_k127_6199639_3	512565.AMIS_18580	5.946e-100	344.0	COG3903@1|root,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
TLS3_k127_6199834_3	234621.RER_43620	6.727e-06	48.0	COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,4FU6Q@85025|Nocardiaceae	201174|Actinobacteria	S	G5	rpfB	-	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
TLS3_k127_6199834_1	1380393.JHVP01000001_gene2255	9.014e-51	190.0	COG3707@1|root,COG3707@2|Bacteria,2I2Q0@201174|Actinobacteria,4EVVD@85013|Frankiales	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
TLS3_k127_6199834_2	526226.Gbro_2564	1.845e-07	61.0	293KS@1|root,2ZR2R@2|Bacteria,2GRFJ@201174|Actinobacteria,4GFEV@85026|Gordoniaceae	201174|Actinobacteria	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
TLS3_k127_6199834_0	1120948.KB903243_gene2463	1.055e-78	271.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DXGB@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpA3	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
TLS3_k127_6200491_0	675635.Psed_3297	2.117e-198	622.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,2GMMC@201174|Actinobacteria,4E076@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.17.1.9,1.6.5.3	ko:K00122,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
TLS3_k127_6200491_1	675635.Psed_3296	6.298e-145	468.0	COG3383@1|root,COG3383@2|Bacteria,2GKBP@201174|Actinobacteria,4DXFK@85010|Pseudonocardiales	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,NADH-G_4Fe-4S_3
TLS3_k127_620241_2	1120948.KB903217_gene1284	1.797e-167	534.0	COG0309@1|root,COG0309@2|Bacteria,2GJ7N@201174|Actinobacteria,4DXSM@85010|Pseudonocardiales	201174|Actinobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
TLS3_k127_620241_1	1120948.KB903217_gene1287	0.0	1019.0	COG0068@1|root,COG0068@2|Bacteria,2GJYF@201174|Actinobacteria,4DYVA@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
TLS3_k127_620241_7	414996.IL38_15100	6.459e-15	84.0	COG0298@1|root,COG0298@2|Bacteria,2GXP3@201174|Actinobacteria	201174|Actinobacteria	O	HupF/HypC family	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
TLS3_k127_620241_5	1120948.KB903217_gene1289	1.774e-51	185.0	COG1695@1|root,COG1695@2|Bacteria,2HRHM@201174|Actinobacteria,4E6XM@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
TLS3_k127_620241_3	1120948.KB903240_gene3962	2.146e-142	464.0	COG0510@1|root,COG0510@2|Bacteria,2I2KR@201174|Actinobacteria,4DZ0D@85010|Pseudonocardiales	201174|Actinobacteria	M	thiamine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
TLS3_k127_620241_0	1120948.KB903240_gene3963	0.0	1050.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4E0SI@85010|Pseudonocardiales	201174|Actinobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
TLS3_k127_620241_4	1120948.KB903240_gene3964	1.031e-61	216.0	COG5015@1|root,COG5015@2|Bacteria,2I3I5@201174|Actinobacteria,4EFCG@85010|Pseudonocardiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
TLS3_k127_6204643_1	1120948.KB903229_gene5134	1.61e-148	488.0	COG2272@1|root,COG2272@2|Bacteria,2GJCN@201174|Actinobacteria,4E1K3@85010|Pseudonocardiales	201174|Actinobacteria	I	Carboxylesterase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
TLS3_k127_6204643_0	1120948.KB903246_gene3188	2.996e-202	641.0	COG0715@1|root,COG0715@2|Bacteria,2GN9B@201174|Actinobacteria,4E0T9@85010|Pseudonocardiales	201174|Actinobacteria	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
TLS3_k127_6204643_2	1120948.KB903246_gene3189	1.313e-40	153.0	COG1359@1|root,COG1359@2|Bacteria,2IM0B@201174|Actinobacteria,4E7ZN@85010|Pseudonocardiales	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
TLS3_k127_6204643_3	1120948.KB903229_gene5136	5.854e-22	95.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4DXQ1@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
TLS3_k127_6206303_4	1120948.KB903217_gene1336	6.598e-46	173.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZX5@85010|Pseudonocardiales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_6206303_3	1380347.JNII01000007_gene212	6.831e-70	248.0	COG1309@1|root,COG1309@2|Bacteria,2IIYZ@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K22108	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
TLS3_k127_6206303_2	469383.Cwoe_2385	1.69e-74	256.0	COG0262@1|root,COG0262@2|Bacteria,2GJJD@201174|Actinobacteria,4CQQ9@84995|Rubrobacteria	84995|Rubrobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
TLS3_k127_6206303_5	2002.JOEQ01000008_gene968	6.085e-07	55.0	2EFYZ@1|root,320WU@2|Bacteria,2I1ZY@201174|Actinobacteria,4EQ7N@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6206303_1	1120948.KB903217_gene1339	5.707e-75	254.0	COG0590@1|root,COG0590@2|Bacteria,2IFH2@201174|Actinobacteria,4E41P@85010|Pseudonocardiales	201174|Actinobacteria	FJ	MafB19-like deaminase	codA	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
TLS3_k127_6206303_0	1120948.KB903217_gene1342	3.045e-129	424.0	COG0266@1|root,COG0266@2|Bacteria,2H39J@201174|Actinobacteria,4DZYU@85010|Pseudonocardiales	201174|Actinobacteria	L	Formamidopyrimidine-DNA glycosylase N-terminal domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
TLS3_k127_6217873_3	1120948.KB903240_gene4051	1.128e-79	269.0	COG3284@1|root,COG3284@2|Bacteria,2GJV4@201174|Actinobacteria,4DYHT@85010|Pseudonocardiales	201174|Actinobacteria	KQ	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF
TLS3_k127_6217873_0	1120948.KB903240_gene4050	3.694e-200	627.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4E362@85010|Pseudonocardiales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.303,1.1.1.4	ko:K00004	ko00650,map00650	-	R02855,R02946,R10504	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_6217873_2	1123023.JIAI01000020_gene2136	4.852e-94	327.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4E4PW@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	butA	-	1.1.1.100,1.1.1.304,1.1.1.76	ko:K00059,ko:K03366	ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R02855,R02946,R03707,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R09078,R10116,R10120,R10505,R11671	RC00029,RC00117,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
TLS3_k127_6217873_4	1120948.KB903240_gene4049	5.433e-30	123.0	2BCCE@1|root,325XT@2|Bacteria,2HB8E@201174|Actinobacteria,4ED3J@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6217873_1	1089455.MOPEL_017_00030	2.468e-141	462.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4F7C9@85018|Dermatophilaceae	201174|Actinobacteria	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
TLS3_k127_6219057_5	994479.GL877878_gene1054	5.106e-98	327.0	COG1398@1|root,COG1398@2|Bacteria,2GJJF@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
TLS3_k127_6219057_2	1120948.KB903232_gene4689	1.849e-124	406.0	COG2146@1|root,COG2146@2|Bacteria,2I1BQ@201174|Actinobacteria,4EDP1@85010|Pseudonocardiales	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231,Rieske
TLS3_k127_6219057_9	471857.Svir_15360	4.654e-25	113.0	2EFXK@1|root,339PU@2|Bacteria,2GTIE@201174|Actinobacteria,4E6WJ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6219057_10	1211815.CBYP010000016_gene2642	2.717e-16	93.0	2E4PM@1|root,32P93@2|Bacteria,2I85P@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6219057_4	1120948.KB903229_gene5291	2.19e-108	363.0	COG1414@1|root,COG1414@2|Bacteria,2I9CD@201174|Actinobacteria,4DYZZ@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
TLS3_k127_6219057_3	1120948.KB903229_gene5292	3.643e-122	399.0	COG3485@1|root,COG3485@2|Bacteria,2GMGM@201174|Actinobacteria,4DZ5N@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protocatechuate 3,4-dioxygenase, beta	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
TLS3_k127_6219057_6	1120948.KB903229_gene5293	7.888e-87	308.0	COG3485@1|root,COG3485@2|Bacteria,2GZGT@201174|Actinobacteria,4E3M4@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protocatechuate 3,4-dioxygenase alpha subunit	pcaG	-	1.13.11.3	ko:K00448	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
TLS3_k127_6219057_1	1120948.KB903229_gene5294	3.71e-180	584.0	COG0654@1|root,COG0654@2|Bacteria,2GM48@201174|Actinobacteria,4DY2I@85010|Pseudonocardiales	201174|Actinobacteria	CH	4-hydroxybenzoate 3-monooxygenase	pobA	-	1.14.13.2	ko:K00481	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R01298	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
TLS3_k127_6219057_0	1120948.KB903245_gene3676	3.239e-208	656.0	COG0297@1|root,COG0297@2|Bacteria	2|Bacteria	G	glycogen (starch) synthase activity	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glyco_transf_5,Glycos_transf_1,Glycos_transf_2
TLS3_k127_6219057_7	1120948.KB903229_gene5295	1.374e-62	227.0	COG1522@1|root,COG1522@2|Bacteria,2IG2K@201174|Actinobacteria,4E52Q@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
TLS3_k127_6219057_8	1120948.KB903229_gene5296	7.693e-48	181.0	COG0697@1|root,COG0697@2|Bacteria,2IPHX@201174|Actinobacteria,4E7TM@85010|Pseudonocardiales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_6230508_0	1120948.KB903223_gene274	1.182e-93	312.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4E0S7@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
TLS3_k127_6230508_9	1449068.JMLQ01000001_gene616	4.857e-05	56.0	2AD8S@1|root,312XT@2|Bacteria,2I87J@201174|Actinobacteria,4FWTX@85025|Nocardiaceae	201174|Actinobacteria	S	Golgi phosphoprotein 3 (GPP34)	-	-	-	-	-	-	-	-	-	-	-	-	GPP34
TLS3_k127_6230508_1	1120948.KB903223_gene276	4.502e-91	311.0	COG3361@1|root,COG3361@2|Bacteria,2I6N0@201174|Actinobacteria,4E5GD@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterized conserved protein (COG2071)	wcoQ	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
TLS3_k127_6230508_7	1122132.AQYH01000018_gene1149	5.234e-15	81.0	2BW2J@1|root,331CU@2|Bacteria,1N7GK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6230508_2	1380393.JHVP01000003_gene815	1.487e-83	285.0	COG1396@1|root,COG1396@2|Bacteria,2GK1R@201174|Actinobacteria,4EV5Y@85013|Frankiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
TLS3_k127_6230508_3	1120948.KB903223_gene275	1.683e-82	299.0	COG0500@1|root,COG2226@2|Bacteria,2II6G@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_6230508_4	1120948.KB903240_gene3730	3.992e-80	276.0	COG0824@1|root,COG0824@2|Bacteria,2GNDK@201174|Actinobacteria,4E5IQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
TLS3_k127_6230508_5	675635.Psed_5592	3.386e-55	203.0	2F76M@1|root,33ZN1@2|Bacteria,2IMIT@201174|Actinobacteria,4E58I@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
TLS3_k127_6230508_6	2074.JNYD01000022_gene1488	6.362e-51	194.0	COG0500@1|root,COG2226@2|Bacteria,2IDNA@201174|Actinobacteria,4E5M5@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_6230508_8	675635.Psed_4426	4.481e-13	74.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,2I3SB@201174|Actinobacteria,4E0KR@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
TLS3_k127_6234814_2	1120948.KB903240_gene3763	5.846e-47	182.0	COG5373@1|root,COG5373@2|Bacteria,2GJII@201174|Actinobacteria,4DYXP@85010|Pseudonocardiales	201174|Actinobacteria	D	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
TLS3_k127_6234814_0	1120948.KB903240_gene3764	4.796e-159	510.0	COG0258@1|root,COG0258@2|Bacteria,2GKTZ@201174|Actinobacteria,4DZJM@85010|Pseudonocardiales	201174|Actinobacteria	L	5'-3' exonuclease	polA_1	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
TLS3_k127_6234814_1	298653.Franean1_6405	2.511e-47	182.0	COG3801@1|root,COG3801@2|Bacteria,2IR6E@201174|Actinobacteria,4EW16@85013|Frankiales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
TLS3_k127_6234814_3	1120948.KB903240_gene3766	1.361e-32	133.0	2BYFJ@1|root,33240@2|Bacteria,2I8PS@201174|Actinobacteria,4E3VC@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4333)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF4333
TLS3_k127_6238553_5	1214101.BN159_8299	4.704e-31	123.0	COG3547@1|root,COG3547@2|Bacteria,2HASG@201174|Actinobacteria	201174|Actinobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
TLS3_k127_6238553_0	1120948.KB903219_gene723	1.353e-295	946.0	COG1216@1|root,COG1216@2|Bacteria,2GM9N@201174|Actinobacteria,4DXNF@85010|Pseudonocardiales	201174|Actinobacteria	NU	PFAM Glycosyl transferase family 2	-	-	2.4.1.288	ko:K16650	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glyco_tranf_2_3
TLS3_k127_6238553_1	1120948.KB903219_gene725	3.125e-247	782.0	COG1835@1|root,COG1835@2|Bacteria,2GKI5@201174|Actinobacteria,4DYJ7@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS3_k127_6238553_3	1120948.KB903219_gene724	6.248e-102	343.0	COG4122@1|root,COG4122@2|Bacteria,2IA2G@201174|Actinobacteria,4E0GD@85010|Pseudonocardiales	201174|Actinobacteria	S	Macrocin-O-methyltransferase (TylF)	-	-	-	ko:K19856,ko:K21325	ko00523,ko01130,map00523,map01130	M00799	R11041,R11469	RC00003,RC00466	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_24,TylF
TLS3_k127_6238553_4	1120948.KB903219_gene727	8.156e-60	222.0	2DZNB@1|root,32VEG@2|Bacteria,2GPZ9@201174|Actinobacteria,4E6YU@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6238553_2	1120948.KB903219_gene725	1.295e-207	666.0	COG1835@1|root,COG1835@2|Bacteria,2GKI5@201174|Actinobacteria,4DYJ7@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
TLS3_k127_6238553_6	1120948.KB903219_gene733	4.866e-28	115.0	COG0697@1|root,COG0697@2|Bacteria,2GRXH@201174|Actinobacteria,4E5V7@85010|Pseudonocardiales	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6247554_1	1120948.KB903244_gene2951	1.592e-160	510.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4E0RB@85010|Pseudonocardiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_6247554_0	1120948.KB903244_gene2952	0.0	1068.0	COG1505@1|root,COG1505@2|Bacteria,2IRXB@201174|Actinobacteria,4E1D1@85010|Pseudonocardiales	201174|Actinobacteria	E	Prolyl oligopeptidase	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
TLS3_k127_6247554_2	73044.JNXP01000003_gene4140	5.831e-13	69.0	COG0454@1|root,COG0456@2|Bacteria,2IFK3@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_6257197_8	1415166.NONO_c32370	1.134e-07	64.0	COG4779@1|root,COG4779@2|Bacteria,2GJ7A@201174|Actinobacteria,4FXCT@85025|Nocardiaceae	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	fepG	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
TLS3_k127_6257197_3	1445613.JALM01000043_gene1622	5.077e-102	354.0	COG0609@1|root,COG0609@2|Bacteria,2GJB9@201174|Actinobacteria,4DXV0@85010|Pseudonocardiales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
TLS3_k127_6257197_5	1123023.JIAI01000001_gene6720	1.581e-75	280.0	COG1535@1|root,COG1535@2|Bacteria,2GK5M@201174|Actinobacteria,4E3AG@85010|Pseudonocardiales	201174|Actinobacteria	Q	Isochorismatase family	-	-	3.3.2.1,6.3.2.14	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R03037,R07644	RC00162,RC00350,RC02148,RC03046	ko00000,ko00001,ko01000,ko01008	-	-	-	Isochorismatase,PP-binding
TLS3_k127_6257197_0	1123023.JIAI01000001_gene6719	6.098e-216	704.0	COG1021@1|root,COG1021@2|Bacteria,2I2IR@201174|Actinobacteria,4DYSN@85010|Pseudonocardiales	201174|Actinobacteria	Q	2,3-dihydroxybenzoate-AMP ligase	dhbE	-	2.7.7.58,6.3.2.14	ko:K02363,ko:K12238	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R07644	RC00162,RC03046	ko00000,ko00001,ko01000,ko01008	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_6257197_4	58123.JOFJ01000027_gene2794	2.725e-98	337.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4EGMX@85012|Streptosporangiales	201174|Actinobacteria	HQ	chorismate binding enzyme	dhbC	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
TLS3_k127_6257197_6	1169154.KB897787_gene709	6.799e-72	255.0	COG1028@1|root,COG1028@2|Bacteria,2GP5U@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	1.3.1.28	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R01505	RC00534	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
TLS3_k127_6257197_1	471852.Tcur_2654	1.279e-150	491.0	COG3486@1|root,COG3486@2|Bacteria,2GKTG@201174|Actinobacteria,4EH54@85012|Streptosporangiales	201174|Actinobacteria	Q	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	1.14.13.195,1.14.13.196	ko:K10531	-	-	-	-	ko00000,ko01000	-	-	-	K_oxygenase
TLS3_k127_6257197_7	1120948.KB903229_gene5080	9.118e-54	193.0	COG2200@1|root,COG2200@2|Bacteria	2|Bacteria	T	EAL domain	-	-	-	ko:K21973	-	-	-	-	ko00000	-	-	-	BLUF
TLS3_k127_6257197_2	1283283.ATXA01000001_gene1214	4.928e-125	413.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4EUDP@85013|Frankiales	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
TLS3_k127_6270191_4	1120948.KB903217_gene1118	1.059e-70	261.0	COG2912@1|root,COG2912@2|Bacteria,2GMER@201174|Actinobacteria,4EARR@85010|Pseudonocardiales	201174|Actinobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
TLS3_k127_6270191_2	1120948.KB903217_gene1117	8.084e-166	539.0	COG5479@1|root,COG5479@2|Bacteria,2GNDB@201174|Actinobacteria,4E40A@85010|Pseudonocardiales	201174|Actinobacteria	M	N-acetylmuramoyl-L-alanine amidase	csp	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,LGFP
TLS3_k127_6270191_6	1120948.KB903217_gene1116	6.334e-68	244.0	28MIG@1|root,2ZAV8@2|Bacteria,2IJSH@201174|Actinobacteria,4E37T@85010|Pseudonocardiales	201174|Actinobacteria	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
TLS3_k127_6270191_5	1120948.KB903217_gene1113	2.464e-70	244.0	2BJDF@1|root,32DPN@2|Bacteria,2GUQ6@201174|Actinobacteria,4EC86@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6270191_1	1120948.KB903217_gene1112	6.426e-217	683.0	COG2272@1|root,COG2272@2|Bacteria,2GJCN@201174|Actinobacteria,4E1UE@85010|Pseudonocardiales	201174|Actinobacteria	I	Carboxylesterase family	lipT	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
TLS3_k127_6270191_0	1123024.AUII01000016_gene1309	8.162e-223	706.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4DXGE@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
TLS3_k127_6270191_3	1120948.KB903217_gene1108	1.162e-136	445.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria,4EA4P@85010|Pseudonocardiales	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	recB	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
TLS3_k127_6286278_3	1121019.AUMN01000008_gene3109	2.486e-16	81.0	COG3629@1|root,COG3629@2|Bacteria,2GM4U@201174|Actinobacteria	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
TLS3_k127_6286278_2	1121019.AUMN01000008_gene3110	9.33e-35	141.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1,4.6.1.2	ko:K01768,ko:K01769	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
TLS3_k127_6286278_1	1173024.KI912148_gene4265	6.895e-81	294.0	COG1752@1|root,COG1752@2|Bacteria,1G2F8@1117|Cyanobacteria,1JKGP@1189|Stigonemataceae	1117|Cyanobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
TLS3_k127_6286278_0	861299.J421_2864	4.095e-110	367.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
TLS3_k127_6291385_2	1120948.KB903228_gene4794	3.137e-178	566.0	COG1921@1|root,COG1921@2|Bacteria,2HFGK@201174|Actinobacteria,4DY7G@85010|Pseudonocardiales	201174|Actinobacteria	E	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
TLS3_k127_6291385_3	1120948.KB903228_gene4792	1.867e-145	482.0	COG3301@1|root,COG3301@2|Bacteria,2GJ4S@201174|Actinobacteria,4DXUA@85010|Pseudonocardiales	201174|Actinobacteria	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
TLS3_k127_6291385_1	1120948.KB903228_gene4791	1.33e-210	676.0	COG0437@1|root,COG0437@2|Bacteria,2I2DV@201174|Actinobacteria,4E0GZ@85010|Pseudonocardiales	201174|Actinobacteria	C	formate dehydrogenase, beta subunit	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3,Fer4_4,Fer4_7
TLS3_k127_6291385_0	1120948.KB903228_gene4790	0.0	1642.0	COG0243@1|root,COG0243@2|Bacteria,2GJCK@201174|Actinobacteria,4DZEM@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
TLS3_k127_6291385_4	1120948.KB903228_gene4789	3.58e-11	63.0	COG0243@1|root,COG0243@2|Bacteria,2GJ7X@201174|Actinobacteria,4E328@85010|Pseudonocardiales	201174|Actinobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	fdhA	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4
TLS3_k127_6346020_3	1120948.KB903243_gene2700	2e-143	468.0	COG2080@1|root,COG3427@1|root,COG2080@2|Bacteria,COG3427@2|Bacteria,2ICYT@201174|Actinobacteria,4E20M@85010|Pseudonocardiales	201174|Actinobacteria	C	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	1.2.5.3,1.5.99.14	ko:K03518,ko:K19186	ko00760,ko01120,map00760,map01120	M00810	R07514,R11168	RC01860,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	COXG,Fer2,Fer2_2
TLS3_k127_6346020_5	675635.Psed_5931	1.512e-94	321.0	COG1319@1|root,COG1319@2|Bacteria,2GP37@201174|Actinobacteria,4E1TC@85010|Pseudonocardiales	201174|Actinobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
TLS3_k127_6346020_4	675635.Psed_5932	6.007e-130	419.0	COG1024@1|root,COG1024@2|Bacteria,2IAHI@201174|Actinobacteria,4E1CE@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	ko:K16880	ko00365,ko01120,map00365,map01120	-	R10210	RC00004,RC01903	ko00000,ko00001	-	-	-	ECH_1
TLS3_k127_6346020_0	675635.Psed_5933	0.0	1180.0	COG1529@1|root,COG1529@2|Bacteria,2I8D1@201174|Actinobacteria,4E1G3@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.8	ko:K16877	ko00365,ko01120,map00365,map01120	-	R02987	RC01856	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
TLS3_k127_6346020_2	1120948.KB903243_gene2696	5.534e-201	639.0	COG0318@1|root,COG0318@2|Bacteria,2HDUJ@201174|Actinobacteria,4DZUM@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.31	ko:K16876	ko00365,ko01120,map00365,map01120	-	R02986	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_6346020_7	675635.Psed_3779	9.991e-65	238.0	COG1695@1|root,COG1695@2|Bacteria,2ISJ2@201174|Actinobacteria,4E5H5@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
TLS3_k127_6346020_1	2074.JNYD01000005_gene3067	2.462e-202	653.0	COG1960@1|root,COG1960@2|Bacteria,2ICBP@201174|Actinobacteria,4E9VT@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
TLS3_k127_6346020_6	2074.JNYD01000005_gene3066	1.107e-90	310.0	COG2207@1|root,COG2207@2|Bacteria,2IRN1@201174|Actinobacteria,4E8E5@85010|Pseudonocardiales	201174|Actinobacteria	K	AraC-binding-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
TLS3_k127_6347086_1	1120948.KB903240_gene3877	1.952e-119	397.0	COG0644@1|root,COG0644@2|Bacteria,2GNH7@201174|Actinobacteria,4DYNV@85010|Pseudonocardiales	201174|Actinobacteria	C	Lycopene cyclase protein	crtL	-	5.5.1.19	ko:K06443	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R03824,R04801,R05341,R06962,R07856	RC01004,RC01964	ko00000,ko00001,ko00002,ko01000	-	-	-	Lycopene_cycl
TLS3_k127_6347086_4	1120948.KB903240_gene3878	5.567e-66	228.0	COG0589@1|root,COG0589@2|Bacteria,2IMMM@201174|Actinobacteria,4E4GY@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein	uspA3	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_6347086_0	1120948.KB903240_gene3879	5.532e-123	404.0	COG2114@1|root,COG2114@2|Bacteria,2GN02@201174|Actinobacteria,4E1TB@85010|Pseudonocardiales	201174|Actinobacteria	T	Adenylate cyclase regulatory domain	cya	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Ad_Cy_reg,Guanylate_cyc
TLS3_k127_6347086_3	1120948.KB903240_gene3880	2.739e-67	237.0	COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,4E4JE@85010|Pseudonocardiales	201174|Actinobacteria	S	metal-sulfur cluster biosynthetic enzyme	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
TLS3_k127_6347086_2	1120948.KB903240_gene3881	2.207e-78	267.0	COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,4E2WE@85010|Pseudonocardiales	201174|Actinobacteria	C	SUF system FeS assembly protein, NifU family	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
TLS3_k127_6347086_5	1120948.KB903240_gene3882	9.177e-23	97.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4DYBX@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
TLS3_k127_6386279_2	1123023.JIAI01000007_gene1826	7.435e-60	228.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4E3IX@85010|Pseudonocardiales	201174|Actinobacteria	V	Domain of unknown function (DUF222)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
TLS3_k127_6386279_1	1120948.KB903217_gene913	9.572e-105	355.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4DXHN@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
TLS3_k127_6386279_4	330084.JNYZ01000030_gene249	2.732e-54	197.0	COG3832@1|root,COG3832@2|Bacteria,2IFZV@201174|Actinobacteria,4E6C5@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Polyketide cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_6386279_0	1156844.KB891831_gene4784	2.457e-154	496.0	COG2141@1|root,COG2141@2|Bacteria,2GNQ1@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_6386279_3	1120948.KB903217_gene914	2.926e-55	213.0	COG1733@1|root,COG1733@2|Bacteria,2IK2D@201174|Actinobacteria,4EB95@85010|Pseudonocardiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
TLS3_k127_6387142_2	1120948.KB903246_gene3222	2.659e-122	399.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GM2E@201174|Actinobacteria,4DY3C@85010|Pseudonocardiales	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD2	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
TLS3_k127_6387142_1	1120948.KB903246_gene3220	3.686e-145	483.0	COG1741@1|root,COG1741@2|Bacteria,2GM9P@201174|Actinobacteria,4E2B4@85010|Pseudonocardiales	201174|Actinobacteria	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
TLS3_k127_6387142_0	1120948.KB903246_gene3219	6.194e-154	499.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4DZPV@85010|Pseudonocardiales	201174|Actinobacteria	C	pfam fad	mcrA	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
TLS3_k127_6387142_3	1120948.KB903246_gene3216	1.268e-16	79.0	COG4270@1|root,COG4270@2|Bacteria,2IQJ5@201174|Actinobacteria,4E5T6@85010|Pseudonocardiales	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
TLS3_k127_6390161_2	1120948.KB903224_gene345	1.704e-20	102.0	COG0464@1|root,COG1222@1|root,COG0464@2|Bacteria,COG1222@2|Bacteria,2GJNW@201174|Actinobacteria,4DX64@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the AAA ATPase family	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_N
TLS3_k127_6390161_0	1120948.KB903224_gene344	2.863e-127	418.0	COG1183@1|root,COG1183@2|Bacteria,2I3MV@201174|Actinobacteria,4DXQ0@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	GO:0003674,GO:0003824,GO:0003882,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_tran_2,CDP-OH_P_transf
TLS3_k127_6390161_1	1120948.KB903224_gene343	4.319e-36	138.0	COG0688@1|root,COG0688@2|Bacteria,2GMMF@201174|Actinobacteria,4DZG8@85010|Pseudonocardiales	201174|Actinobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
TLS3_k127_6401072_2	1120948.KB903229_gene5175	4.458e-40	156.0	COG3583@1|root,COG3583@2|Bacteria,2I5N9@201174|Actinobacteria	201174|Actinobacteria	S	Transglycosylase-like domain	-	-	-	ko:K21687	-	-	-	-	ko00000	-	GH23	-	Transglycosylas
TLS3_k127_6401072_1	1120948.KB903229_gene5176	5.08e-72	253.0	COG2265@1|root,COG2265@2|Bacteria,2H4HE@201174|Actinobacteria,4EE3J@85010|Pseudonocardiales	201174|Actinobacteria	J	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
TLS3_k127_6401072_0	1120948.KB903229_gene5177	1.149e-171	548.0	COG0438@1|root,COG0438@2|Bacteria,2GIZG@201174|Actinobacteria,4DYB5@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyltransferase Family 4	mgtA	GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K12583	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
TLS3_k127_6419951_1	1286093.C266_09242	1.733e-117	394.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2VIGQ@28216|Betaproteobacteria,1K395@119060|Burkholderiaceae	28216|Betaproteobacteria	EH	Belongs to the TPP enzyme family	mdlC	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TLS3_k127_6419951_3	1134445.AJJM01000117_gene1989	2.827e-55	201.0	COG5483@1|root,COG5483@2|Bacteria,2IHSH@201174|Actinobacteria	201174|Actinobacteria	L	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
TLS3_k127_6419951_0	1120948.KB903240_gene3902	5.235e-261	806.0	COG1350@1|root,COG1350@2|Bacteria,2GP7D@201174|Actinobacteria,4DZNN@85010|Pseudonocardiales	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_6419951_2	1120948.KB903240_gene3903	2.439e-63	218.0	2CNY9@1|root,31GEE@2|Bacteria,2IKKZ@201174|Actinobacteria,4E4N7@85010|Pseudonocardiales	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	-	-	-	-	-	-	-	-	-	-	-	RbpA
TLS3_k127_6419951_4	1120948.KB903240_gene3904	4.041e-36	138.0	COG1314@1|root,COG1314@2|Bacteria,2GR31@201174|Actinobacteria,4E5MY@85010|Pseudonocardiales	201174|Actinobacteria	U	PFAM Preprotein translocase SecG subunit	secG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
TLS3_k127_6423858_5	653045.Strvi_6193	4.662e-34	131.0	COG0702@1|root,COG0702@2|Bacteria,2GKXI@201174|Actinobacteria	201174|Actinobacteria	GM	PFAM NmrA family protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
TLS3_k127_6423858_3	1137269.AZWL01000015_gene639	2.942e-65	229.0	COG5015@1|root,COG5015@2|Bacteria,2IMRG@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
TLS3_k127_6423858_1	1120948.KB903220_gene64	2.624e-166	529.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4DZU7@85010|Pseudonocardiales	201174|Actinobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA
TLS3_k127_6423858_0	1120948.KB903220_gene65	4.533e-197	620.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4DZJH@85010|Pseudonocardiales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
TLS3_k127_6423858_2	1120948.KB903220_gene66	2.158e-94	316.0	COG1385@1|root,COG1385@2|Bacteria,2GTKX@201174|Actinobacteria,4DY8U@85010|Pseudonocardiales	201174|Actinobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
TLS3_k127_6423858_4	1120948.KB903220_gene67	1.1e-35	149.0	COG1506@1|root,COG1506@2|Bacteria,2I3Z4@201174|Actinobacteria,4E53V@85010|Pseudonocardiales	201174|Actinobacteria	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Abhydrolase_6,Peptidase_S9
TLS3_k127_6430384_3	543632.JOJL01000027_gene2898	3.409e-41	166.0	COG0589@1|root,COG4978@1|root,COG0589@2|Bacteria,COG4978@2|Bacteria,2ICPM@201174|Actinobacteria,4DCQW@85008|Micromonosporales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_6430384_2	1120948.KB903217_gene1509	1.163e-57	207.0	COG1309@1|root,COG1309@2|Bacteria,2IIZR@201174|Actinobacteria,4EEXV@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_6430384_0	1206743.BAGM01000056_gene5328	3.132e-233	731.0	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria,4FUI3@85025|Nocardiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_6430384_1	1120948.KB903217_gene1514	2.184e-88	304.0	COG0596@1|root,COG0596@2|Bacteria,2GJDM@201174|Actinobacteria,4DYHZ@85010|Pseudonocardiales	201174|Actinobacteria	CH	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
TLS3_k127_6440495_4	1123023.JIAI01000011_gene8808	3.503e-227	722.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4E01D@85010|Pseudonocardiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
TLS3_k127_6440495_12	1120948.KB903217_gene1459	4.588e-113	370.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4DXA3@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit	nuoE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
TLS3_k127_6440495_2	1120948.KB903217_gene1458	1.66e-258	802.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4DZ6H@85010|Pseudonocardiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
TLS3_k127_6440495_11	1120948.KB903217_gene1457	3.413e-127	412.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,4DY4U@85010|Pseudonocardiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
TLS3_k127_6440495_13	1120948.KB903217_gene1456	1.432e-110	368.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4DYGD@85010|Pseudonocardiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
TLS3_k127_6440495_16	1179773.BN6_80340	1.654e-57	203.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria,4E3G5@85010|Pseudonocardiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
TLS3_k127_6440495_6	1120948.KB903217_gene1454	1.332e-183	602.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,4DYSG@85010|Pseudonocardiales	201174|Actinobacteria	C	TIGRFAM geranylgeranyl reductase	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
TLS3_k127_6440495_14	1380356.JNIK01000018_gene712	2.628e-93	321.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4ERZ2@85013|Frankiales	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
TLS3_k127_6440495_19	1120948.KB903217_gene1452	1.636e-49	190.0	2EDS1@1|root,337MI@2|Bacteria,2IQ90@201174|Actinobacteria,4E5HZ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
TLS3_k127_6440495_17	656024.FsymDg_2715	5.229e-53	207.0	COG1503@1|root,COG1503@2|Bacteria,2GNN3@201174|Actinobacteria,4EVI4@85013|Frankiales	201174|Actinobacteria	J	translation release factor activity	-	GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	-
TLS3_k127_6440495_34	1045855.DSC_10030	1.641e-07	56.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RRVF@1236|Gammaproteobacteria,1X5F1@135614|Xanthomonadales	135614|Xanthomonadales	V	COG0286 Type I restriction-modification system methyltransferase subunit	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
TLS3_k127_6440495_27	65497.JODV01000006_gene956	2.792e-17	92.0	COG1320@1|root,COG1320@2|Bacteria,2GRNP@201174|Actinobacteria	201174|Actinobacteria	P	monovalent cation proton antiporter, MnhG PhaG subunit	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
TLS3_k127_6440495_31	65497.JODV01000006_gene955	2.233e-16	85.0	COG2212@1|root,COG2212@2|Bacteria,2GT6H@201174|Actinobacteria	201174|Actinobacteria	P	Multisubunit Na H antiporter, MnhF subunit	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
TLS3_k127_6440495_35	1489678.RDMS_06675	4.147e-07	56.0	COG1863@1|root,COG1863@2|Bacteria,1WKP6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Multisubunit Na H antiporter MnhE subunit	-	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
TLS3_k127_6440495_7	446469.Sked_26950	8.569e-162	533.0	COG0651@1|root,COG0651@2|Bacteria,2HAC7@201174|Actinobacteria	201174|Actinobacteria	CP	Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	mnhD	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
TLS3_k127_6440495_22	1292020.H483_0101785	2.257e-33	132.0	COG1006@1|root,COG1006@2|Bacteria,2IR2B@201174|Actinobacteria	201174|Actinobacteria	P	Multisubunit Na H antiporter MnhC subunit	mnhC	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
TLS3_k127_6440495_1	136273.GY22_04605	1.812e-277	884.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,2GIT4@201174|Actinobacteria,1W7KW@1268|Micrococcaceae	201174|Actinobacteria	CP	Domain related to MnhB subunit of Na+/H+ antiporter	mnhB	-	-	ko:K05565,ko:K14086	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB,NADHdh,Proton_antipo_M,Proton_antipo_N
TLS3_k127_6440495_25	1122611.KB903939_gene527	8.4e-20	97.0	2E7YB@1|root,332CR@2|Bacteria,2IRTP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
TLS3_k127_6440495_26	479431.Namu_4632	5.068e-18	93.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4ES3E@85013|Frankiales	201174|Actinobacteria	L	PFAM transposase IS204 IS1001 IS1096 IS1165 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
TLS3_k127_6440495_23	1120948.KB903217_gene1451	7.452e-30	130.0	COG1320@1|root,COG1320@2|Bacteria,2IQXD@201174|Actinobacteria,4E5R1@85010|Pseudonocardiales	201174|Actinobacteria	P	monovalent cation proton antiporter, MnhG PhaG subunit	mrpG	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
TLS3_k127_6440495_28	1120948.KB903217_gene1450	3.709e-17	85.0	COG2212@1|root,COG2212@2|Bacteria	2|Bacteria	P	antiporter activity	mrpF	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
TLS3_k127_6440495_20	1120948.KB903217_gene1449	7.021e-41	174.0	COG1863@1|root,COG1863@2|Bacteria,2IQD6@201174|Actinobacteria,4E5KJ@85010|Pseudonocardiales	201174|Actinobacteria	P	Multisubunit Na H antiporter, MnhE subunit	mrpE	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
TLS3_k127_6440495_3	1120948.KB903217_gene1448	4.212e-228	732.0	COG0651@1|root,COG0651@2|Bacteria,2HAC7@201174|Actinobacteria,4DXG9@85010|Pseudonocardiales	201174|Actinobacteria	CP	Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	mrpD	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
TLS3_k127_6440495_18	1120948.KB903217_gene1447	4.63e-50	186.0	COG1006@1|root,COG1006@2|Bacteria,2ISBC@201174|Actinobacteria,4E4NP@85010|Pseudonocardiales	201174|Actinobacteria	P	Multisubunit Na H antiporter, MnhC subunit	mrpC	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
TLS3_k127_6440495_0	1120948.KB903217_gene1446	0.0	1158.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,2GIT4@201174|Actinobacteria,4DZ06@85010|Pseudonocardiales	201174|Actinobacteria	CP	NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	mrpA/mrpB	-	-	ko:K05565,ko:K14086	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
TLS3_k127_6440495_5	1120948.KB903217_gene1445	3.346e-204	653.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,4DYET@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
TLS3_k127_6440495_9	1120948.KB903217_gene1444	9.675e-139	454.0	COG3103@1|root,COG4991@2|Bacteria,2IA2V@201174|Actinobacteria,4DZ1K@85010|Pseudonocardiales	201174|Actinobacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6440495_10	1120948.KB903217_gene1443	1.512e-127	413.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4DX8T@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
TLS3_k127_6440495_15	1160137.KB907308_gene6634	8.155e-61	228.0	COG3832@1|root,COG3832@2|Bacteria,2IHY4@201174|Actinobacteria,4G1HM@85025|Nocardiaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_6440495_33	288705.RSal33209_0564	1.708e-10	67.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,1W7HH@1268|Micrococcaceae	201174|Actinobacteria	V	HNH nucleases	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH
TLS3_k127_6440495_21	1120948.KB903218_gene2072	4.357e-37	157.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4E32T@85010|Pseudonocardiales	201174|Actinobacteria	L	HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH
TLS3_k127_6440495_30	1041522.MCOL_V207490	2.012e-16	87.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,232NV@1762|Mycobacteriaceae	201174|Actinobacteria	V	Domain of unknown function (DUF222)	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
TLS3_k127_6440495_24	1120948.KB903217_gene1441	3.158e-28	114.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4E6G1@85010|Pseudonocardiales	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
TLS3_k127_6440495_8	1120948.KB903217_gene1436	2.422e-158	512.0	COG0455@1|root,COG0455@2|Bacteria,2GMK0@201174|Actinobacteria,4DXEP@85010|Pseudonocardiales	201174|Actinobacteria	D	ATPase involved in chromosome	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
TLS3_k127_6454611_10	1120948.KB903244_gene2958	3.743e-34	136.0	COG0454@1|root,COG0456@2|Bacteria,2IFK3@201174|Actinobacteria,4E5CQ@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_6454611_8	326424.FRAAL1468	8.235e-54	207.0	COG0346@1|root,COG0346@2|Bacteria,2IKP7@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_6454611_4	1123023.JIAI01000016_gene3357	5.52e-83	289.0	COG1309@1|root,COG1309@2|Bacteria,2GQBQ@201174|Actinobacteria,4DYX0@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
TLS3_k127_6454611_12	33898.JRHJ01000078_gene970	1.808e-16	94.0	COG0596@1|root,COG0596@2|Bacteria,2HEMJ@201174|Actinobacteria	201174|Actinobacteria	E	hydrolases or acyltransferases alpha beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
TLS3_k127_6454611_13	1463879.JOHP01000070_gene3006	2.457e-08	66.0	COG2267@1|root,COG2267@2|Bacteria,2I3Z6@201174|Actinobacteria	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
TLS3_k127_6454611_1	1120948.KB903229_gene5319	4.532e-132	432.0	COG2807@1|root,COG2807@2|Bacteria,2GP5W@201174|Actinobacteria,4E0SN@85010|Pseudonocardiales	201174|Actinobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K03449	-	-	-	-	ko00000,ko02000	2.A.1.17	-	-	MFS_1
TLS3_k127_6454611_6	298655.KI912267_gene7929	8.207e-60	230.0	COG1752@1|root,COG1752@2|Bacteria,2IB0F@201174|Actinobacteria	201174|Actinobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
TLS3_k127_6454611_0	1120948.KB903240_gene4084	0.0	1222.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria,4E1FZ@85010|Pseudonocardiales	201174|Actinobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppsA	-	2.7.9.2	ko:K01007,ko:K21787	ko00333,ko00620,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00333,map00620,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00374,M00837,M00838	R00199,R11662,R11673	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
TLS3_k127_6454611_9	1464048.JNZS01000003_gene1200	8.915e-40	164.0	2CP0Z@1|root,32SI8@2|Bacteria,2IHXV@201174|Actinobacteria,4DF6N@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF3037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3037
TLS3_k127_6454611_2	1120948.KB903244_gene2957	1.515e-115	376.0	COG1718@1|root,COG1718@2|Bacteria,2GKX1@201174|Actinobacteria,4E1RE@85010|Pseudonocardiales	201174|Actinobacteria	DT	Serine threonine protein kinase involved in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6454611_7	1122609.AUGT01000012_gene4276	1.866e-54	205.0	2DM23@1|root,31DUR@2|Bacteria,2GIYZ@201174|Actinobacteria,4DS07@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BON,DUF2204,NTP_transf_5
TLS3_k127_6454611_5	446466.Cfla_2832	2.12e-68	241.0	COG3568@1|root,COG3568@2|Bacteria,2GP3V@201174|Actinobacteria,4F2KM@85016|Cellulomonadaceae	201174|Actinobacteria	L	PFAM Endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_6454611_11	2055.JNXA01000011_gene3070	3.091e-27	120.0	2CCA5@1|root,34A9Y@2|Bacteria,2GQ4A@201174|Actinobacteria,4GD1R@85026|Gordoniaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6454611_3	1464048.JNZS01000003_gene1166	1.446e-114	400.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2GJAR@201174|Actinobacteria,4DMFR@85008|Micromonosporales	201174|Actinobacteria	KT	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
TLS3_k127_6469880_2	675635.Psed_1648	1.264e-32	136.0	COG1388@1|root,COG1388@2|Bacteria,2I3RK@201174|Actinobacteria,4E5WX@85010|Pseudonocardiales	201174|Actinobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6469880_1	68260.JOAY01000045_gene1311	1.497e-41	159.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	rocE	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
TLS3_k127_6469880_3	590998.Celf_1765	5.386e-23	114.0	COG0589@1|root,COG0589@2|Bacteria,2I8XM@201174|Actinobacteria	201174|Actinobacteria	T	universal stress protein	uspA4	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_6469880_0	1120948.KB903223_gene263	4.452e-178	558.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,4DXCZ@85010|Pseudonocardiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
TLS3_k127_6478762_1	1120948.KB903223_gene270	1.04e-80	275.0	COG4221@1|root,COG4221@2|Bacteria,2GP05@201174|Actinobacteria,4EB9D@85010|Pseudonocardiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_6478762_0	1120948.KB903223_gene271	1.669e-177	559.0	COG1072@1|root,COG1072@2|Bacteria,2GIRR@201174|Actinobacteria,4DXVW@85010|Pseudonocardiales	201174|Actinobacteria	H	Pantothenic acid kinase	coaA	GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.33	ko:K00867	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
TLS3_k127_6478762_3	1120948.KB903223_gene272	4.676e-56	199.0	COG1846@1|root,COG1846@2|Bacteria,2IH3H@201174|Actinobacteria,4E4SB@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
TLS3_k127_6478762_2	1120948.KB903223_gene273	8.971e-70	240.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB
TLS3_k127_6499483_0	1120948.KB903218_gene2107	0.0	1084.0	COG0642@1|root,COG2205@2|Bacteria,2GJKC@201174|Actinobacteria,4E0PS@85010|Pseudonocardiales	201174|Actinobacteria	T	Osmosensitive K+ channel His kinase sensor domain	kdpD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
TLS3_k127_6499483_1	1120948.KB903218_gene2108	1.136e-115	382.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4DZ76@85010|Pseudonocardiales	201174|Actinobacteria	T	Member of the two-component regulatory system kdpD kdpE involved in the regulation of the kdp operon	kdpE	GO:0008150,GO:0040007	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_6499483_2	1120948.KB903218_gene2129	1.106e-94	323.0	COG0477@1|root,COG2814@2|Bacteria,2GN6N@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_4
TLS3_k127_6503879_1	1120948.KB903246_gene3190	1.205e-67	233.0	COG1960@1|root,COG1960@2|Bacteria,2IEV9@201174|Actinobacteria,4E89V@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
TLS3_k127_6503879_0	102129.Lepto7375DRAFT_3732	2.134e-120	399.0	COG0654@1|root,COG0654@2|Bacteria,1G27G@1117|Cyanobacteria,1HA6Z@1150|Oscillatoriales	1117|Cyanobacteria	CH	PFAM FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
TLS3_k127_6521903_2	1120948.KB903244_gene2993	8.582e-71	262.0	COG1020@1|root,COG1020@2|Bacteria,2GKU0@201174|Actinobacteria,4E3DM@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
TLS3_k127_6521903_1	1120948.KB903229_gene5090	8.144e-95	338.0	COG0204@1|root,COG0560@1|root,COG0204@2|Bacteria,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria	201174|Actinobacteria	E	HAD-superfamily subfamily IB hydrolase, TIGR01490	-	-	2.3.1.51,3.1.3.3	ko:K15781	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,HAD
TLS3_k127_6521903_0	1120948.KB903229_gene5089	2.226e-129	428.0	COG2937@1|root,COG2937@2|Bacteria,2GMQF@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the GPAT DAPAT family	plsB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
TLS3_k127_6522075_2	675635.Psed_6100	2.111e-71	253.0	COG0245@1|root,COG0245@2|Bacteria,2II8H@201174|Actinobacteria,4E2MV@85010|Pseudonocardiales	201174|Actinobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0051483,GO:0071704,GO:1901576	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3581c	YgbB
TLS3_k127_6522075_3	1120948.KB903229_gene5403	3.466e-60	218.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,4DXFF@85010|Pseudonocardiales	201174|Actinobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
TLS3_k127_6522075_1	1120948.KB903229_gene5402	1.755e-95	313.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4DXYN@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	carD	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
TLS3_k127_6522075_5	1120948.KB903229_gene5401	1.52e-35	145.0	COG2847@1|root,COG2847@2|Bacteria,2H1IZ@201174|Actinobacteria	201174|Actinobacteria	S	Copper chaperone PCu(A)C	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6522075_0	1120948.KB903229_gene5400	5.628e-199	630.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4DZGZ@85010|Pseudonocardiales	201174|Actinobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
TLS3_k127_6522075_4	1120948.KB903229_gene5399	3.839e-39	148.0	COG1572@1|root,COG1572@2|Bacteria,2I2R9@201174|Actinobacteria,4E4VU@85010|Pseudonocardiales	201174|Actinobacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	DUF4232
TLS3_k127_6526312_1	1123024.AUII01000037_gene4384	4.412e-119	392.0	COG0464@1|root,COG0464@2|Bacteria,2GJWA@201174|Actinobacteria,4E0IY@85010|Pseudonocardiales	201174|Actinobacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
TLS3_k127_6526312_2	1123024.AUII01000014_gene4278	1.405e-110	372.0	COG0583@1|root,COG0583@2|Bacteria,2GMES@201174|Actinobacteria,4E9PT@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
TLS3_k127_6526312_4	675635.Psed_6248	6.171e-92	319.0	COG3588@1|root,COG3588@2|Bacteria,2GJ0D@201174|Actinobacteria,4E286@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Fructose-bisphosphate aldolase, class-I	-	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
TLS3_k127_6526312_0	1120948.KB903224_gene301	4.393e-253	789.0	COG0535@1|root,COG0535@2|Bacteria,2GNSY@201174|Actinobacteria,4DZNS@85010|Pseudonocardiales	201174|Actinobacteria	C	Radical SAM	pqqE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
TLS3_k127_6526312_6	1120948.KB903224_gene302	1.568e-38	148.0	COG0535@1|root,COG0535@2|Bacteria,2GQQT@201174|Actinobacteria,4E725@85010|Pseudonocardiales	201174|Actinobacteria	S	Mycofactocin system	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6526312_5	1120948.KB903224_gene304	4.925e-53	198.0	COG1309@1|root,COG1309@2|Bacteria,2HFWX@201174|Actinobacteria,4E3JF@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	mftR	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_6526312_7	1120948.KB903224_gene305	8.9e-34	142.0	COG1725@1|root,COG1725@2|Bacteria,2IQEW@201174|Actinobacteria,4E5BM@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GntR
TLS3_k127_6526312_3	1120948.KB903224_gene306	1.289e-100	333.0	COG1028@1|root,COG1028@2|Bacteria,2GKVM@201174|Actinobacteria,4E3Y7@85010|Pseudonocardiales	201174|Actinobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_6535819_1	1120948.KB903217_gene1157	1.194e-107	353.0	COG0402@1|root,COG0402@2|Bacteria,2GM63@201174|Actinobacteria,4E0CV@85010|Pseudonocardiales	201174|Actinobacteria	F	Amidohydrolase family	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
TLS3_k127_6535819_2	1120948.KB903217_gene1155	2.803e-105	359.0	COG1432@1|root,COG1432@2|Bacteria,2GMV5@201174|Actinobacteria,4E9GP@85010|Pseudonocardiales	201174|Actinobacteria	S	NYN domain	-	-	-	ko:K06860	-	-	-	-	ko00000	-	-	-	NYN
TLS3_k127_6535819_0	1120948.KB903217_gene1154	1.069e-111	366.0	COG0220@1|root,COG0220@2|Bacteria,2GJ8R@201174|Actinobacteria,4DY5Q@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
TLS3_k127_6535819_4	1120948.KB903217_gene1153	5.227e-27	119.0	2F1A3@1|root,33UB3@2|Bacteria,2IPJY@201174|Actinobacteria,4E646@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6535819_3	1120948.KB903217_gene1152	7.414e-78	268.0	COG0699@1|root,COG0699@2|Bacteria,2GK6T@201174|Actinobacteria,4DYJX@85010|Pseudonocardiales	201174|Actinobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
TLS3_k127_6555503_0	1463858.JOHR01000001_gene6539	0.0	1214.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	-	ko:K12955	-	-	-	-	ko00000,ko01000	3.A.3.24	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
TLS3_k127_6555503_2	1120948.KB903218_gene2025	1.746e-142	474.0	COG0654@1|root,COG0654@2|Bacteria,2GIWF@201174|Actinobacteria,4E490@85010|Pseudonocardiales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
TLS3_k127_6555503_11	1120948.KB903218_gene2023	2.366e-45	170.0	COG0789@1|root,COG0789@2|Bacteria,2IKRM@201174|Actinobacteria,4E4DY@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM MerR family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
TLS3_k127_6555503_4	1120948.KB903218_gene2022	1.792e-88	314.0	COG0515@1|root,COG0515@2|Bacteria,2IAZC@201174|Actinobacteria,4DXAZ@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TLS3_k127_6555503_7	1120948.KB903218_gene2017	6.018e-59	230.0	COG2337@1|root,COG2337@2|Bacteria,2GM10@201174|Actinobacteria,4E4W4@85010|Pseudonocardiales	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
TLS3_k127_6555503_13	1120948.KB903218_gene2012	2.215e-24	117.0	2EBHT@1|root,335I8@2|Bacteria,2GMT9@201174|Actinobacteria,4E76H@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6555503_8	1120948.KB903218_gene2010	4.369e-57	217.0	COG0631@1|root,COG0631@2|Bacteria,2GKDM@201174|Actinobacteria,4E20G@85010|Pseudonocardiales	201174|Actinobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	prpB10	-	-	-	-	-	-	-	-	-	-	-	DZR,PP2C_2
TLS3_k127_6555503_1	1122182.KB903839_gene962	7.288e-160	518.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4D9ZK@85008|Micromonosporales	201174|Actinobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
TLS3_k127_6555503_3	36809.MAB_4711	8.002e-97	342.0	COG0451@1|root,COG0451@2|Bacteria,2GNH5@201174|Actinobacteria	201174|Actinobacteria	GM	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS3_k127_6555503_6	43354.JOIJ01000001_gene228	2.471e-78	275.0	COG0654@1|root,COG0654@2|Bacteria,2GIZU@201174|Actinobacteria,4E1PV@85010|Pseudonocardiales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,NAD_binding_8
TLS3_k127_6555503_12	1303692.SFUL_740	1.765e-32	143.0	COG3226@1|root,COG3226@2|Bacteria,2IQ9B@201174|Actinobacteria	201174|Actinobacteria	K	TetR Family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
TLS3_k127_6555503_5	675635.Psed_4453	3.703e-88	312.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria,4E3CN@85010|Pseudonocardiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
TLS3_k127_6555503_10	1120948.KB903218_gene2005	4.213e-50	196.0	COG0789@1|root,COG0789@2|Bacteria,2IFX0@201174|Actinobacteria,4E6WK@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
TLS3_k127_6555503_9	1440774.Y900_007655	2.023e-50	186.0	COG0697@1|root,COG0697@2|Bacteria,2GKVT@201174|Actinobacteria,2331W@1762|Mycobacteriaceae	201174|Actinobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	ydeD	-	-	-	-	-	-	-	-	-	-	-	EamA
TLS3_k127_6591472_1	1120948.KB903244_gene2807	4.301e-11	76.0	COG0596@1|root,COG0596@2|Bacteria,2HCC5@201174|Actinobacteria,4DXCR@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
TLS3_k127_6591472_0	1120948.KB903244_gene2806	4.427e-175	556.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4DX83@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA ligase	ligC	GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
TLS3_k127_6596196_2	1120948.KB903245_gene3425	2.748e-24	103.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria,4DXVI@85010|Pseudonocardiales	201174|Actinobacteria	S	Sterol carrier protein domain	eis	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
TLS3_k127_6596196_0	1120948.KB903244_gene3173	8.517e-177	559.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4DY4T@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA primase, small subunit	ligD	-	-	-	-	-	-	-	-	-	-	-	DNA_primase_S
TLS3_k127_6596196_1	1120948.KB903244_gene3172	1.637e-78	269.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4EBET@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_6596836_14	1157634.KB912966_gene2193	2.633e-13	70.0	COG1917@1|root,COG1917@2|Bacteria,2IQI4@201174|Actinobacteria	201174|Actinobacteria	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_6596836_7	1120948.KB903247_gene4588	9.507e-166	542.0	COG1960@1|root,COG1960@2|Bacteria,2H7DI@201174|Actinobacteria,4DXXD@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_6596836_1	1120948.KB903243_gene2492	4.636e-213	671.0	COG2141@1|root,COG2141@2|Bacteria,2GJAN@201174|Actinobacteria,4E0ES@85010|Pseudonocardiales	201174|Actinobacteria	C	FMN-dependent oxidoreductase (Nitrilotriacetate monooxygenase family)	-	-	1.14.14.28	ko:K20938	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
TLS3_k127_6596836_5	1120948.KB903247_gene4589	5.068e-189	603.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4DZVP@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_6596836_11	1120948.KB903247_gene4590	7.96e-93	306.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria,4E0ZX@85010|Pseudonocardiales	201174|Actinobacteria	P	Reversible hydration of carbon dioxide	mtcA1	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008270,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
TLS3_k127_6596836_8	1120948.KB903247_gene4548	1.633e-127	427.0	COG4424@1|root,COG4424@2|Bacteria	2|Bacteria	S	carbohydrate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
TLS3_k127_6596836_10	1120948.KB903247_gene4547	1.549e-119	396.0	COG1621@1|root,COG1621@2|Bacteria,2GKT1@201174|Actinobacteria	201174|Actinobacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6596836_12	1120948.KB903247_gene4546	2.843e-79	274.0	COG0529@1|root,COG0529@2|Bacteria,2GMUK@201174|Actinobacteria,4E3VP@85010|Pseudonocardiales	201174|Actinobacteria	P	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25,2.7.7.4	ko:K00860,ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
TLS3_k127_6596836_4	1120948.KB903247_gene4591	5.774e-199	641.0	COG2895@1|root,COG2895@2|Bacteria,2GJDX@201174|Actinobacteria,4DYZW@85010|Pseudonocardiales	201174|Actinobacteria	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
TLS3_k127_6596836_6	1120948.KB903247_gene4592	9.376e-168	545.0	COG0175@1|root,COG0175@2|Bacteria,2GN85@201174|Actinobacteria,4DXTN@85010|Pseudonocardiales	201174|Actinobacteria	EH	TIGRFAM sulfate adenylyltransferase, small subunit	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
TLS3_k127_6596836_9	1120948.KB903247_gene4593	5.765e-121	402.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria,4DZCB@85010|Pseudonocardiales	201174|Actinobacteria	EH	Reduction of activated sulfate into sulfite	cysH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004604,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016667,GO:0016671,GO:0019344,GO:0019752,GO:0040007,GO:0043436,GO:0043866,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2392	PAPS_reduct
TLS3_k127_6596836_17	1123023.JIAI01000012_gene9213	1.385e-06	60.0	COG3677@1|root,COG3677@2|Bacteria,2GQKE@201174|Actinobacteria,4EEAU@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6596836_0	1120948.KB903247_gene4594	0.0	1031.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4DZSG@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	sir	-	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
TLS3_k127_6596836_3	1120948.KB903247_gene4583	5.16e-199	647.0	COG2141@1|root,COG2141@2|Bacteria,2GJ0S@201174|Actinobacteria,4DZHY@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	ssuD	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
TLS3_k127_6596836_2	1120948.KB903247_gene4582	1.225e-210	665.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4E0CD@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_6596836_15	710685.MycrhN_1388	4.425e-07	61.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,23296@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Guanylate_cyc,Pkinase
TLS3_k127_6596836_16	1265310.CCBD010000005_gene2687	1.304e-06	58.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,23296@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknJ	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,VCBS
TLS3_k127_6596836_13	1120948.KB903247_gene4595	7.497e-45	163.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4DXMC@85010|Pseudonocardiales	201174|Actinobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
TLS3_k127_6620392_3	1120948.KB903248_gene4366	6.069e-65	231.0	COG3243@1|root,COG3243@2|Bacteria,2GP7I@201174|Actinobacteria,4DY42@85010|Pseudonocardiales	201174|Actinobacteria	I	synthetase	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,PHB_depo_C
TLS3_k127_6620392_1	1120948.KB903248_gene4362	1.476e-106	354.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,4EAXI@85010|Pseudonocardiales	201174|Actinobacteria	I	Carboxylesterase family	lip	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
TLS3_k127_6620392_0	2074.JNYD01000007_gene2189	1.133e-205	685.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4E1HN@85010|Pseudonocardiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_6620392_2	2074.JNYD01000007_gene2188	1.295e-82	284.0	COG0596@1|root,COG0596@2|Bacteria,2HAZ1@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6632070_1	1120948.KB903225_gene5553	2.999e-81	288.0	COG5297@1|root,COG5297@2|Bacteria,2HDPZ@201174|Actinobacteria,4E329@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 12	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_12,RicinB_lectin_2,Ricin_B_lectin
TLS3_k127_6632070_0	1120948.KB903225_gene5554	1.653e-291	914.0	COG1506@1|root,COG1506@2|Bacteria,2GJ6A@201174|Actinobacteria,4DZ08@85010|Pseudonocardiales	201174|Actinobacteria	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	pepX	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
TLS3_k127_6632070_2	1298608.JCM18900_12655	2.346e-17	93.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,3NIKH@468|Moraxellaceae	1236|Gammaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
TLS3_k127_664036_10	1120948.KB903240_gene3942	1.361e-72	245.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4DYGN@85010|Pseudonocardiales	201174|Actinobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
TLS3_k127_664036_11	1120948.KB903240_gene3941	2.872e-55	199.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,4E3S8@85010|Pseudonocardiales	201174|Actinobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0008150,GO:0040007	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
TLS3_k127_664036_7	1120948.KB903240_gene3940	2.871e-93	308.0	COG1395@1|root,COG1395@2|Bacteria,2GVFR@201174|Actinobacteria,4DZHC@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	bldD	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
TLS3_k127_664036_9	1120948.KB903240_gene3939	5.143e-83	280.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,4DZ0J@85010|Pseudonocardiales	201174|Actinobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
TLS3_k127_664036_5	1120948.KB903240_gene3938	5.983e-170	545.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4E04H@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
TLS3_k127_664036_1	1120948.KB903240_gene3937	1.095e-229	715.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4DXZ8@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
TLS3_k127_664036_3	1120948.KB903240_gene3936	3.079e-189	596.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4DYFR@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1383	CPSase_sm_chain,GATase
TLS3_k127_664036_0	1120934.KB894439_gene5785	0.0	1713.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4E0DG@85010|Pseudonocardiales	201174|Actinobacteria	EF	Belongs to the CarB family	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
TLS3_k127_664036_6	1120948.KB903240_gene3934	3.951e-98	355.0	COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4DXGR@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
TLS3_k127_664036_12	1120948.KB903240_gene3933	1.918e-47	174.0	COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria,4E4HM@85010|Pseudonocardiales	201174|Actinobacteria	J	integration host factor	mihF	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_664036_8	1120948.KB903240_gene3932	6.821e-86	289.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4E1VY@85010|Pseudonocardiales	201174|Actinobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
TLS3_k127_664036_13	1123023.JIAI01000002_gene5433	6.503e-41	163.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4E5KY@85010|Pseudonocardiales	201174|Actinobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
TLS3_k127_664036_4	1120948.KB903240_gene3930	2.351e-187	597.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,4DYU5@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
TLS3_k127_664036_2	1120948.KB903240_gene3929	5.695e-225	700.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4DXAM@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
TLS3_k127_6643436_1	1157634.KB912952_gene6133	1.323e-47	191.0	COG0346@1|root,COG0346@2|Bacteria,2IKKR@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_6643436_0	1120948.KB903224_gene285	8.185e-133	439.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,2GITG@201174|Actinobacteria,4DZSQ@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix proteins, AraC family	alkA	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
TLS3_k127_6643436_2	675635.Psed_4298	1.541e-32	128.0	COG1877@1|root,COG1877@2|Bacteria,2H9EY@201174|Actinobacteria,4ECE1@85010|Pseudonocardiales	201174|Actinobacteria	G	trehalose-phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6655911_6	2074.JNYD01000028_gene7258	4.151e-12	68.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4DY23@85010|Pseudonocardiales	201174|Actinobacteria	L	PFAM Transposase, mutator type	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
TLS3_k127_6655911_5	1121372.AULK01000016_gene475	1.149e-13	75.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4FM91@85023|Microbacteriaceae	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
TLS3_k127_6655911_3	309801.trd_A0333	6.812e-45	177.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	-	GO:0003674,GO:0003824,GO:0004300,GO:0016829,GO:0016835,GO:0016836	-	ko:K16425	ko01055,ko01130,map01055,map01130	-	R06625	RC00004,RC02933	ko00000,ko00001	-	-	-	ECH_1
TLS3_k127_6655911_0	1282876.BAOK01000001_gene1391	1.195e-111	379.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_6655911_4	1120949.KB903294_gene3842	2.972e-42	165.0	COG3467@1|root,COG3467@2|Bacteria,2IR80@201174|Actinobacteria,4DMRQ@85008|Micromonosporales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K05558	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
TLS3_k127_6655911_1	1123023.JIAI01000002_gene5488	1.047e-52	198.0	COG0251@1|root,COG0251@2|Bacteria,2IHP3@201174|Actinobacteria,4E5PH@85010|Pseudonocardiales	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
TLS3_k127_6655911_2	105425.BBPL01000034_gene4197	3.279e-45	166.0	COG2318@1|root,COG2318@2|Bacteria,2IGJQ@201174|Actinobacteria	201174|Actinobacteria	H	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
TLS3_k127_6672754_3	710421.Mycch_0153	8.084e-08	56.0	COG1309@1|root,COG1309@2|Bacteria,2IFEN@201174|Actinobacteria,23C63@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
TLS3_k127_6672754_1	1463920.JOGB01000004_gene4706	5.2e-55	207.0	COG0122@1|root,COG0122@2|Bacteria,2GP69@201174|Actinobacteria	201174|Actinobacteria	L	3-methyladenine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6672754_0	2074.JNYD01000001_gene6245	2.411e-173	551.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4DXPJ@85010|Pseudonocardiales	201174|Actinobacteria	GM	PFAM NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS3_k127_6672754_2	2074.JNYD01000001_gene6244	1.256e-25	124.0	COG0382@1|root,COG0382@2|Bacteria,2GJT3@201174|Actinobacteria,4E3NH@85010|Pseudonocardiales	201174|Actinobacteria	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
TLS3_k127_6673270_2	1429046.RR21198_4073	1.128e-82	280.0	COG1595@1|root,COG1595@2|Bacteria,2GN4D@201174|Actinobacteria,4FYW0@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_6673270_1	675635.Psed_6090	2.942e-91	321.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,2GJMC@201174|Actinobacteria,4DZ2V@85010|Pseudonocardiales	201174|Actinobacteria	S	Threonine/Serine exporter, ThrE	thrE	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
TLS3_k127_6673270_0	164757.Mjls_4992	1.039e-186	595.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,2332Q@1762|Mycobacteriaceae	201174|Actinobacteria	G	Probably involved in the osmoprotection via the biosynthesis of trehalose and in the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P). Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Probably also able to use ADP-Glc, CDP-Glc, GDP-Glc and TDP-Glc as glucosyl donors	otsA	GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
TLS3_k127_6674132_0	1120948.KB903217_gene922	1.136e-156	508.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4DZBG@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
TLS3_k127_6674132_1	1120948.KB903217_gene923	8.085e-103	341.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4E04P@85010|Pseudonocardiales	201174|Actinobacteria	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
TLS3_k127_6674132_7	1120948.KB903217_gene924	8.954e-33	132.0	2E4NY@1|root,32ZHR@2|Bacteria,2GQPW@201174|Actinobacteria,4E5D0@85010|Pseudonocardiales	201174|Actinobacteria	D	involved in cell division	crgA	-	-	-	-	-	-	-	-	-	-	-	CrgA
TLS3_k127_6674132_6	1120948.KB903217_gene925	8.107e-36	143.0	2ESQF@1|root,33K8W@2|Bacteria,2GRJ0@201174|Actinobacteria,4E6FA@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_6
TLS3_k127_6674132_3	1123024.AUII01000002_gene905	2.818e-79	274.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4E02H@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TLS3_k127_6674132_2	1120948.KB903217_gene927	3.444e-89	310.0	COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4DX47@85010|Pseudonocardiales	201174|Actinobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
TLS3_k127_6674132_4	1120948.KB903217_gene929	9.401e-79	279.0	COG4099@1|root,COG4099@2|Bacteria,2GJDU@201174|Actinobacteria,4E4H6@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Alpha beta hydrolase of	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_8
TLS3_k127_6681459_1	1120948.KB903243_gene2562	3.154e-105	353.0	28NWB@1|root,2ZBU7@2|Bacteria,2GJ74@201174|Actinobacteria,4DZWY@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3027)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3027
TLS3_k127_6681459_0	1120948.KB903243_gene2561	5.017e-271	868.0	COG3225@1|root,COG3225@2|Bacteria,2GMTX@201174|Actinobacteria,4DY63@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6681459_3	1229205.BUPH_08527	2.44e-07	60.0	COG5659@1|root,COG5659@2|Bacteria,1MWAV@1224|Proteobacteria,2W56T@28216|Betaproteobacteria,1KIBA@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
TLS3_k127_6681459_2	1435356.Y013_13195	1.439e-65	230.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria,4FYPK@85025|Nocardiaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
TLS3_k127_668649_3	909613.UO65_4508	8.093e-08	62.0	COG4585@1|root,COG4585@2|Bacteria,2GUXI@201174|Actinobacteria,4E6TH@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
TLS3_k127_668649_2	1123023.JIAI01000003_gene3010	1.56e-102	349.0	COG2197@1|root,COG2197@2|Bacteria,2GYMP@201174|Actinobacteria,4E2HE@85010|Pseudonocardiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_668649_1	1123023.JIAI01000003_gene3011	3.205e-107	379.0	COG2203@1|root,COG2203@2|Bacteria,2I3SD@201174|Actinobacteria,4E6YQ@85010|Pseudonocardiales	201174|Actinobacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_668649_0	1123023.JIAI01000003_gene3012	4.867e-189	635.0	COG0699@1|root,COG4585@1|root,COG0699@2|Bacteria,COG4585@2|Bacteria,2GSBK@201174|Actinobacteria,4E183@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TLS3_k127_6707951_0	1394178.AWOO02000024_gene5600	1.528e-182	583.0	COG1960@1|root,COG1960@2|Bacteria,2HEJ2@201174|Actinobacteria,4EG2T@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_6707951_1	40571.JOEA01000034_gene873	1.754e-114	398.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4DZ01@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
TLS3_k127_6707951_2	1120948.KB903247_gene4629	5.72e-77	272.0	COG3012@1|root,COG3012@2|Bacteria,2GV65@201174|Actinobacteria,4E7DR@85010|Pseudonocardiales	201174|Actinobacteria	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
TLS3_k127_6707951_3	543632.JOJL01000027_gene2623	1.456e-34	137.0	COG1289@1|root,COG1289@2|Bacteria,2GN9U@201174|Actinobacteria,4DCD6@85008|Micromonosporales	201174|Actinobacteria	S	Fusaric acid resistance protein-like	yccS_1	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
TLS3_k127_6726428_1	1120948.KB903218_gene2033	1.347e-140	452.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4DXMM@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_6726428_4	1120948.KB903218_gene2032	5.983e-61	214.0	COG0494@1|root,COG0494@2|Bacteria,2II4D@201174|Actinobacteria,4EF9E@85010|Pseudonocardiales	201174|Actinobacteria	L	NUDIX domain	mutT3	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
TLS3_k127_6726428_2	1120948.KB903218_gene2031	3.867e-115	382.0	COG2170@1|root,COG2170@2|Bacteria,2GKAA@201174|Actinobacteria,4DXHV@85010|Pseudonocardiales	201174|Actinobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
TLS3_k127_6726428_0	1120948.KB903218_gene2030	2.448e-173	560.0	COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria,4DX7H@85010|Pseudonocardiales	201174|Actinobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
TLS3_k127_6726428_5	1120948.KB903218_gene2028	1.287e-31	132.0	2CC1Y@1|root,34BAK@2|Bacteria,2IM7Z@201174|Actinobacteria	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
TLS3_k127_6726428_3	1120948.KB903218_gene2027	3.967e-81	280.0	2DND7@1|root,32WWM@2|Bacteria,2GXXS@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2188
TLS3_k127_6726428_6	1120948.KB903218_gene2026	2.634e-07	53.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4DZN7@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	ko:K12955	-	-	-	-	ko00000,ko01000	3.A.3.24	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
TLS3_k127_6766567_2	1120948.KB903248_gene4385	2.562e-115	382.0	COG1055@1|root,COG1055@2|Bacteria,2GMQJ@201174|Actinobacteria,4DXTC@85010|Pseudonocardiales	201174|Actinobacteria	P	Arsenical pump membrane protein	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
TLS3_k127_6766567_4	675635.Psed_2027	1.543e-103	349.0	COG4427@1|root,COG4427@2|Bacteria,2HVQW@201174|Actinobacteria,4DX9D@85010|Pseudonocardiales	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
TLS3_k127_6766567_10	1120948.KB903248_gene4387	1.237e-83	294.0	COG0406@1|root,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,4E04U@85010|Pseudonocardiales	201174|Actinobacteria	GL	phosphoglycerate mutase	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
TLS3_k127_6766567_9	1120948.KB903248_gene4388	2.068e-84	304.0	COG1579@1|root,COG1579@2|Bacteria,2GP84@201174|Actinobacteria,4DZFM@85010|Pseudonocardiales	201174|Actinobacteria	S	Zn-ribbon protein	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
TLS3_k127_6766567_3	1120948.KB903248_gene4389	3.136e-105	368.0	COG0327@1|root,COG0327@2|Bacteria,2GKHZ@201174|Actinobacteria,4DXZJ@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM NIF3 (NGG1p interacting factor 3)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	NIF3
TLS3_k127_6766567_14	1120948.KB903229_gene5271	9.101e-26	124.0	COG1266@1|root,COG1266@2|Bacteria,2HZR1@201174|Actinobacteria,4EDD8@85010|Pseudonocardiales	2|Bacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
TLS3_k127_6766567_12	1120948.KB903248_gene4392	2.872e-55	199.0	COG0394@1|root,COG0394@2|Bacteria,2IM0Q@201174|Actinobacteria,4E4IK@85010|Pseudonocardiales	201174|Actinobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	ptpA	GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0035335,GO:0035821,GO:0036211,GO:0042578,GO:0043170,GO:0043207,GO:0043412,GO:0044003,GO:0044046,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052046,GO:0052047,GO:0052048,GO:0052083,GO:0052155,GO:0052173,GO:0052200,GO:0052212,GO:0052255,GO:0052278,GO:0052294,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:0140096,GO:1901564	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
TLS3_k127_6766567_5	1120948.KB903248_gene4393	4.321e-101	341.0	COG3001@1|root,COG3001@2|Bacteria,2GW7W@201174|Actinobacteria,4DZV2@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
TLS3_k127_6766567_7	1120948.KB903248_gene4394	9.993e-97	323.0	COG3346@1|root,COG3346@2|Bacteria,2GR90@201174|Actinobacteria,4DYT0@85010|Pseudonocardiales	201174|Actinobacteria	S	SURF1-like protein	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	SURF1
TLS3_k127_6766567_1	2074.JNYD01000016_gene4220	3.453e-120	394.0	COG1270@1|root,COG1270@2|Bacteria,2GMB8@201174|Actinobacteria,4E06P@85010|Pseudonocardiales	201174|Actinobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
TLS3_k127_6766567_8	1120948.KB903248_gene4396	2.048e-94	324.0	COG0819@1|root,COG0819@2|Bacteria,2IA0S@201174|Actinobacteria,4E3B5@85010|Pseudonocardiales	201174|Actinobacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	-	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
TLS3_k127_6766567_11	1120948.KB903248_gene4401	1.721e-62	224.0	COG1247@1|root,COG1247@2|Bacteria,2IHSY@201174|Actinobacteria,4E4T5@85010|Pseudonocardiales	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
TLS3_k127_6766567_0	1120948.KB903218_gene2221	1.083e-209	662.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4DZE6@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
TLS3_k127_67781_1	1120948.KB903229_gene5357	1.353e-125	410.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4DYX6@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Uncharacterised conserved protein (DUF2342)	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
TLS3_k127_67781_0	1120948.KB903229_gene5356	1.384e-153	499.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4DY9B@85010|Pseudonocardiales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
TLS3_k127_67781_2	40571.JOEA01000010_gene2853	1.343e-76	284.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4DXQ1@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
TLS3_k127_678469_1	526225.Gobs_3190	3.144e-10	63.0	COG1403@1|root,COG1403@2|Bacteria,2IRX4@201174|Actinobacteria,4EW07@85013|Frankiales	201174|Actinobacteria	V	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
TLS3_k127_678469_0	1120948.KB903217_gene1069	1.11e-208	663.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4DX7R@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Alpha amylase, catalytic	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
TLS3_k127_6837863_2	1123023.JIAI01000006_gene56	2.498e-151	481.0	COG0425@1|root,COG0425@2|Bacteria,2I4E3@201174|Actinobacteria,4E932@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6837863_4	1120948.KB903224_gene288	3.049e-88	306.0	COG3568@1|root,COG3568@2|Bacteria,2GNF9@201174|Actinobacteria,4E7GN@85010|Pseudonocardiales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
TLS3_k127_6837863_6	426355.Mrad2831_0633	1.104e-10	74.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	1.13.11.24	ko:K07155	-	-	-	-	ko00000,ko01000	-	-	-	Cupin_2
TLS3_k127_6837863_3	1120948.KB903218_gene1838	1.22e-108	361.0	COG0332@1|root,COG0332@2|Bacteria,2GJP8@201174|Actinobacteria,4DZJP@85010|Pseudonocardiales	201174|Actinobacteria	I	catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
TLS3_k127_6837863_5	1236902.ANAS01000004_gene3733	1.932e-50	182.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
TLS3_k127_6837863_0	1120948.KB903244_gene2815	3.384e-229	717.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4DXKQ@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
TLS3_k127_6837863_1	1120948.KB903244_gene2816	2.959e-159	512.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria,4DX7B@85010|Pseudonocardiales	201174|Actinobacteria	S	Reductase C-terminal	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
TLS3_k127_6843496_4	1120948.KB903248_gene4317	1.163e-15	77.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,2GMC0@201174|Actinobacteria,4E0J9@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase III, epsilon subunit	dnaQ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
TLS3_k127_6843496_2	1120948.KB903248_gene4318	1.405e-36	143.0	COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria,4E5G7@85010|Pseudonocardiales	201174|Actinobacteria	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
TLS3_k127_6843496_0	1120948.KB903248_gene4320	8.944e-152	494.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4DYFX@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
TLS3_k127_6843496_1	1120948.KB903248_gene4321	3.016e-60	211.0	COG0784@1|root,COG0784@2|Bacteria,2II71@201174|Actinobacteria,4E3K9@85010|Pseudonocardiales	201174|Actinobacteria	T	response regulator	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_6843496_3	1120948.KB903248_gene4322	1.19e-27	114.0	COG1845@1|root,COG1845@2|Bacteria,2GKK8@201174|Actinobacteria,4DYVY@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM cytochrome c oxidase subunit III	ctaE	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
TLS3_k127_6862518_3	1120948.KB903219_gene625	3.506e-28	120.0	COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4E1GK@85010|Pseudonocardiales	201174|Actinobacteria	E	Methionine synthase	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
TLS3_k127_6862518_1	1120948.KB903219_gene624	2.983e-105	349.0	COG1414@1|root,COG1414@2|Bacteria,2GP0G@201174|Actinobacteria,4E3ZA@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
TLS3_k127_6862518_0	1123023.JIAI01000010_gene8505	4.715e-124	410.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4E0C3@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
TLS3_k127_6862518_2	1120948.KB903219_gene623	9.107e-35	133.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,4DXVG@85010|Pseudonocardiales	201174|Actinobacteria	G	hydrolase, family 65, central catalytic	-	-	2.4.1.64	ko:K05342	ko00500,ko01100,map00500,map01100	-	R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
TLS3_k127_6866469_7	58344.JOEL01000121_gene3245	2.42e-33	130.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
TLS3_k127_6866469_8	1229205.BUPH_08527	8.048e-08	57.0	COG5659@1|root,COG5659@2|Bacteria,1MWAV@1224|Proteobacteria,2W56T@28216|Betaproteobacteria,1KIBA@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
TLS3_k127_6866469_0	405948.SACE_1758	1.211e-249	775.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4E9CU@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase	tnp3508a	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
TLS3_k127_6866469_6	591167.Sfla_4116	2.188e-82	287.0	COG2207@1|root,COG2207@2|Bacteria,2GITD@201174|Actinobacteria	201174|Actinobacteria	K	Arac family	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
TLS3_k127_6866469_1	208444.JNYY01000008_gene8525	2.743e-170	555.0	COG2986@1|root,COG2986@2|Bacteria,2GK17@201174|Actinobacteria,4DZ91@85010|Pseudonocardiales	201174|Actinobacteria	E	Aromatic amino acid lyase	hutH_1	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
TLS3_k127_6866469_4	1068978.AMETH_1156	6.688e-141	478.0	COG1228@1|root,COG1228@2|Bacteria,2GJH4@201174|Actinobacteria,4DXEX@85010|Pseudonocardiales	201174|Actinobacteria	Q	TIGRFAM imidazolonepropionase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
TLS3_k127_6866469_3	1068978.AMETH_1155	1.541e-147	490.0	COG0402@1|root,COG0402@2|Bacteria,2GZ2Q@201174|Actinobacteria,4DXKJ@85010|Pseudonocardiales	201174|Actinobacteria	F	Formiminoglutamate deiminase	hutF	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
TLS3_k127_6866469_2	43354.JOIJ01000004_gene3777	2.605e-148	489.0	COG0624@1|root,COG0624@2|Bacteria,2GJDE@201174|Actinobacteria,4DXJV@85010|Pseudonocardiales	201174|Actinobacteria	E	Peptidase family M28	amaB	-	3.5.1.6,3.5.1.87,3.5.3.9	ko:K02083,ko:K06016	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00046	R00905,R02423,R04666	RC00064,RC00096	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_6866469_5	1068978.AMETH_1153	1.528e-111	361.0	COG2987@1|root,COG2987@2|Bacteria,2GP10@201174|Actinobacteria,4DXID@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
TLS3_k127_6867804_4	1380393.JHVP01000002_gene1891	2.805e-10	62.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4ETBC@85013|Frankiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
TLS3_k127_6867804_2	1120948.KB903217_gene1517	3.541e-169	545.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4E0N9@85010|Pseudonocardiales	201174|Actinobacteria	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF
TLS3_k127_6867804_1	1120948.KB903217_gene1516	3.388e-202	638.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4E4GS@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the CinA family	cinA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
TLS3_k127_6867804_3	1172181.KB911712_gene2222	3.525e-90	310.0	COG2267@1|root,COG2267@2|Bacteria,2GPA8@201174|Actinobacteria	201174|Actinobacteria	I	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
TLS3_k127_6867804_5	1120948.KB903217_gene1512	3.241e-10	73.0	COG0596@1|root,COG0596@2|Bacteria,2HFDT@201174|Actinobacteria,4E74H@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
TLS3_k127_6867804_0	1120948.KB903244_gene2993	5.588e-239	745.0	COG1020@1|root,COG1020@2|Bacteria,2GKU0@201174|Actinobacteria,4E3DM@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
TLS3_k127_6882907_0	1120948.KB903244_gene3047	2.756e-172	544.0	COG0438@1|root,COG0438@2|Bacteria,2GIZG@201174|Actinobacteria,4DYB5@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_6882907_1	1120948.KB903244_gene3048	2.738e-128	419.0	COG1082@1|root,COG1082@2|Bacteria,2GK34@201174|Actinobacteria,4E0J6@85010|Pseudonocardiales	201174|Actinobacteria	G	Sugar phosphate isomerase epimerase	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	AP_endonuc_2
TLS3_k127_6882907_2	1120948.KB903217_gene1308	1.837e-102	342.0	COG1414@1|root,COG1414@2|Bacteria,2ISM5@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator (IclR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
TLS3_k127_6908866_0	1120948.KB903240_gene3974	0.0	2560.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,2GN09@201174|Actinobacteria,4DX9H@85010|Pseudonocardiales	201174|Actinobacteria	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
TLS3_k127_6908866_2	1068980.ARVW01000001_gene5618	1.541e-221	696.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4DYTC@85010|Pseudonocardiales	201174|Actinobacteria	E	NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
TLS3_k127_6908866_6	66874.JOFS01000009_gene2770	4.884e-39	149.0	COG4319@1|root,COG4319@2|Bacteria,2IMG5@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
TLS3_k127_6908866_5	1160137.KB907308_gene7439	1.37e-54	202.0	COG2267@1|root,COG2267@2|Bacteria,2GK6S@201174|Actinobacteria,4G3AV@85025|Nocardiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
TLS3_k127_6908866_4	1120948.KB903240_gene3972	1.818e-93	314.0	COG0652@1|root,COG0652@2|Bacteria,2GN8G@201174|Actinobacteria,4DY7N@85010|Pseudonocardiales	201174|Actinobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
TLS3_k127_6908866_3	1120948.KB903240_gene3971	2.315e-124	402.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,4E019@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
TLS3_k127_6908866_1	1120948.KB903240_gene3970	2.066e-224	713.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4DYW0@85010|Pseudonocardiales	201174|Actinobacteria	J	histidyl-tRNA synthetase	hisS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
TLS3_k127_6923398_14	318424.EU78_26685	2.832e-06	49.0	COG1024@1|root,COG1024@2|Bacteria,2I9DY@201174|Actinobacteria,234K7@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
TLS3_k127_6923398_6	1120948.KB903219_gene748	1.846e-85	294.0	COG5340@1|root,COG5340@2|Bacteria,2ICBY@201174|Actinobacteria,4E4UK@85010|Pseudonocardiales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
TLS3_k127_6923398_0	1120948.KB903229_gene5351	1.656e-205	644.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4DYCP@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the thiolase family	pcaF	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
TLS3_k127_6923398_5	1120948.KB903229_gene5350	1.19e-87	293.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria,4E3KT@85010|Pseudonocardiales	201174|Actinobacteria	I	dehydratase	-	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
TLS3_k127_6923398_2	1120948.KB903229_gene5349	1.34e-182	575.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4DXE3@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_6923398_10	1120948.KB903229_gene5348	3.374e-44	165.0	COG0824@1|root,COG0824@2|Bacteria,2GTT4@201174|Actinobacteria,4E777@85010|Pseudonocardiales	201174|Actinobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
TLS3_k127_6923398_7	1120948.KB903229_gene5347	3.15e-84	284.0	COG1853@1|root,COG1853@2|Bacteria,2GK9V@201174|Actinobacteria,4E32B@85010|Pseudonocardiales	201174|Actinobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
TLS3_k127_6923398_13	1120948.KB903229_gene5346	4.327e-22	110.0	2E39G@1|root,32Y91@2|Bacteria,2GQNT@201174|Actinobacteria,4E5VN@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6923398_3	1120948.KB903229_gene5345	1.263e-136	445.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4E55Q@85010|Pseudonocardiales	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	1.8.3.1	ko:K00387	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00533	RC00168	ko00000,ko00001,ko01000	-	-	-	Mo-co_dimer,Oxidored_molyb
TLS3_k127_6923398_11	1120948.KB903229_gene5343	2.38e-42	159.0	COG2149@1|root,COG2149@2|Bacteria,2GQU9@201174|Actinobacteria,4E6UJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF202)	yidH	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
TLS3_k127_6923398_12	1120948.KB903229_gene5342	1.159e-23	112.0	2AXTU@1|root,31PUT@2|Bacteria,2I1IA@201174|Actinobacteria,4EDA0@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF202
TLS3_k127_6923398_8	1120948.KB903229_gene5344	9.014e-78	271.0	COG0438@1|root,COG0438@2|Bacteria,2I3HH@201174|Actinobacteria,4EE7Z@85010|Pseudonocardiales	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Mg_trans_NIPA
TLS3_k127_6923398_1	1120948.KB903229_gene5339	1.291e-190	612.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4E02E@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_6923398_4	1120948.KB903229_gene5338	1.049e-106	356.0	COG4932@1|root,COG4932@2|Bacteria,2I3FW@201174|Actinobacteria,4EC3P@85010|Pseudonocardiales	201174|Actinobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1
TLS3_k127_6923398_9	1120948.KB903240_gene3783	4.261e-55	206.0	COG2852@1|root,COG2852@2|Bacteria,2GKCY@201174|Actinobacteria,4EB4D@85010|Pseudonocardiales	201174|Actinobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4,DUF559
TLS3_k127_6925302_0	1120948.KB903240_gene4021	1.201e-171	546.0	COG5502@1|root,COG5502@2|Bacteria,2I9TQ@201174|Actinobacteria,4E0PF@85010|Pseudonocardiales	201174|Actinobacteria	S	conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6925302_13	1197706.AKKK01000062_gene1708	1.253e-27	118.0	2BKAB@1|root,32EQK@2|Bacteria,2GXJB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6925302_8	1120948.KB903217_gene821	1.564e-45	175.0	2E4Q9@1|root,32ZIV@2|Bacteria,2II59@201174|Actinobacteria,4E3H2@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative transmembrane protein (PGPGW)	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
TLS3_k127_6925302_6	1120948.KB903217_gene820	5.454e-51	195.0	COG5343@1|root,COG5343@2|Bacteria,2HM9H@201174|Actinobacteria,4E3TB@85010|Pseudonocardiales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
TLS3_k127_6925302_4	675635.Psed_2039	5.871e-77	264.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4E2NI@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
TLS3_k127_6925302_5	1120948.KB903217_gene818	8.997e-74	250.0	arCOG03175@1|root,32RFA@2|Bacteria,2IFE3@201174|Actinobacteria,4E2JR@85010|Pseudonocardiales	201174|Actinobacteria	S	sporulation and cell division protein, SsgA	-	-	-	-	-	-	-	-	-	-	-	-	SsgA
TLS3_k127_6925302_14	1120948.KB903217_gene814	3.494e-21	99.0	2EHMB@1|root,33BD3@2|Bacteria,2I3SC@201174|Actinobacteria,4EF8N@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6925302_7	65497.JODV01000002_gene4200	5.164e-50	190.0	COG4639@1|root,COG4639@2|Bacteria,2I9VQ@201174|Actinobacteria,4E756@85010|Pseudonocardiales	201174|Actinobacteria	S	AAA domain	pseT	-	6.5.1.3	ko:K14680	-	-	-	-	ko00000,ko01000	-	-	-	AAA_33,RNA_lig_T4_1
TLS3_k127_6925302_2	1120948.KB903217_gene813	1.028e-98	329.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4E55M@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
TLS3_k127_6925302_1	1120948.KB903217_gene812	6.806e-151	482.0	COG0604@1|root,COG0604@2|Bacteria,2GK7Y@201174|Actinobacteria,4DXY4@85010|Pseudonocardiales	201174|Actinobacteria	C	NADPH quinone reductase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_6925302_3	1120948.KB903244_gene2762	4.359e-80	272.0	COG3897@1|root,COG3897@2|Bacteria,2II39@201174|Actinobacteria,4E3UH@85010|Pseudonocardiales	201174|Actinobacteria	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PrmA
TLS3_k127_6925302_11	1120948.KB903244_gene2763	1.045e-29	123.0	2FIGG@1|root,34A8J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6925302_9	1120948.KB903244_gene2764	5.95e-39	150.0	2CH6Y@1|root,2ZPPZ@2|Bacteria,2IQJM@201174|Actinobacteria,4E6G9@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6925302_10	1120948.KB903247_gene4452	7.121e-34	142.0	COG1309@1|root,COG1309@2|Bacteria,2GP2Z@201174|Actinobacteria,4E6W0@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
TLS3_k127_6925302_12	1120948.KB903244_gene2765	3.515e-28	115.0	COG4581@1|root,COG4581@2|Bacteria,2GJSV@201174|Actinobacteria,4DXMY@85010|Pseudonocardiales	201174|Actinobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
TLS3_k127_6936397_13	1385520.N802_18795	1.582e-06	49.0	COG4101@1|root,COG4101@2|Bacteria,2II42@201174|Actinobacteria,4FGN5@85021|Intrasporangiaceae	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_6936397_7	1380390.JIAT01000010_gene4823	5.205e-129	417.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4CPRX@84995|Rubrobacteria	84995|Rubrobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
TLS3_k127_6936397_0	1120948.KB903248_gene4255	0.0	2123.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4DZKF@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase III alpha subunit	dnaE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
TLS3_k127_6936397_11	1240349.ANGC01000038_gene3211	6.588e-51	184.0	COG3324@1|root,COG3324@2|Bacteria,2IRXF@201174|Actinobacteria,4G1IK@85025|Nocardiaceae	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS3_k127_6936397_4	1120948.KB903248_gene4251	1.13e-168	531.0	COG0235@1|root,COG0235@2|Bacteria,2GJ8W@201174|Actinobacteria,4E37X@85010|Pseudonocardiales	201174|Actinobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
TLS3_k127_6936397_6	1120948.KB903248_gene4250	2.095e-146	477.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria,4DZEJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
TLS3_k127_6936397_10	1120948.KB903243_gene2467	7.901e-64	231.0	COG1309@1|root,COG1309@2|Bacteria,2INTE@201174|Actinobacteria,4E5Z1@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_6936397_1	1120948.KB903243_gene2466	1.774e-201	643.0	COG0477@1|root,COG0477@2|Bacteria,2GMEJ@201174|Actinobacteria,4E2CH@85010|Pseudonocardiales	201174|Actinobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_6936397_3	2074.JNYD01000007_gene1980	2.313e-185	614.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DYZ8@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_6936397_8	1120948.KB903248_gene4235	2.054e-110	366.0	COG3327@1|root,COG3327@2|Bacteria,2GNME@201174|Actinobacteria,4E1NE@85010|Pseudonocardiales	201174|Actinobacteria	K	PaaX-like protein	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
TLS3_k127_6936397_2	1169154.KB897791_gene249	2.12e-187	602.0	COG0161@1|root,COG0161@2|Bacteria,2I2DN@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	GO:0003674,GO:0003824,GO:0004015,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
TLS3_k127_6936397_5	1120948.KB903248_gene4232	4.332e-157	525.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,4DXXC@85010|Pseudonocardiales	201174|Actinobacteria	E	8-amino-7-oxononanoate synthase	bioF	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.3.1.47,6.2.1.14	ko:K00652,ko:K01906	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03209,R03210,R10124	RC00004,RC00014,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iNJ661.Rv1569	Aminotran_1_2,BioW
TLS3_k127_6936397_9	1120948.KB903218_gene1804	2.366e-83	288.0	2BSCK@1|root,32MEH@2|Bacteria,2HDAB@201174|Actinobacteria,4EDJN@85010|Pseudonocardiales	1120948.KB903218_gene1804|-	S	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6936397_12	526225.Gobs_2553	5.311e-07	61.0	COG2172@1|root,COG2172@2|Bacteria,2GKU6@201174|Actinobacteria,4EWI3@85013|Frankiales	201174|Actinobacteria	T	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MEDS
TLS3_k127_6971805_2	1125971.ASJB01000017_gene6087	2.013e-27	112.0	COG1119@1|root,COG1119@2|Bacteria,2GIXX@201174|Actinobacteria,4DY0S@85010|Pseudonocardiales	201174|Actinobacteria	P	ABC-type molybdenum transport system, ATPase component photorepair protein PhrA	ylmA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
TLS3_k127_6971805_0	1120948.KB903245_gene3606	1.689e-294	922.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4DZ0M@85010|Pseudonocardiales	201174|Actinobacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	glgX	-	3.2.1.196,3.2.1.68	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
TLS3_k127_6971805_1	1120948.KB903240_gene3783	2.262e-53	193.0	COG2852@1|root,COG2852@2|Bacteria,2GKCY@201174|Actinobacteria,4EB4D@85010|Pseudonocardiales	201174|Actinobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4,DUF559
TLS3_k127_6985858_8	105420.BBPO01000049_gene1765	8.74e-26	124.0	COG0451@1|root,COG0451@2|Bacteria,2GP24@201174|Actinobacteria,2NEQC@228398|Streptacidiphilus	201174|Actinobacteria	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS3_k127_6985858_4	1370121.AUWS01000022_gene6352	3.26e-79	304.0	COG0477@1|root,COG0477@2|Bacteria,2IAI1@201174|Actinobacteria,2370X@1762|Mycobacteriaceae	201174|Actinobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_6985858_0	1120948.KB903221_gene527	6.425e-271	847.0	COG4178@1|root,COG4178@2|Bacteria,2IAEM@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	bacA	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0043207,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071944,GO:0075136	-	ko:K02471	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.203.11,3.A.1.203.4	-	-	ABC_membrane_2,ABC_tran
TLS3_k127_6985858_5	1120948.KB903217_gene1653	1.108e-76	270.0	COG4544@1|root,COG4544@2|Bacteria,2IIXE@201174|Actinobacteria,4E4BH@85010|Pseudonocardiales	201174|Actinobacteria	S	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division	-	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6985858_1	1120948.KB903217_gene1654	7.718e-266	833.0	COG0389@1|root,COG0389@2|Bacteria,2GMZ3@201174|Actinobacteria,4DZGC@85010|Pseudonocardiales	201174|Actinobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	dinB_2	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
TLS3_k127_6985858_2	526225.Gobs_2857	3.589e-155	495.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria,4ETNA@85013|Frankiales	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
TLS3_k127_6985858_3	526225.Gobs_2858	1.853e-145	478.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria,4ESG6@85013|Frankiales	201174|Actinobacteria	K	Sigma-70, region 4 type 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
TLS3_k127_6985858_6	1298880.AUEV01000003_gene3323	9.622e-48	182.0	2CRSQ@1|root,32SEJ@2|Bacteria,2I336@201174|Actinobacteria	201174|Actinobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
TLS3_k127_6985858_7	1120948.KB903217_gene1655	1.937e-36	153.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4DYKC@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
TLS3_k127_6987599_1	1120948.KB903219_gene698	1.531e-96	322.0	COG0561@1|root,COG0561@2|Bacteria,2GP42@201174|Actinobacteria,4DXB6@85010|Pseudonocardiales	201174|Actinobacteria	S	HAD-superfamily hydrolase, subfamily IIB	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
TLS3_k127_6987599_2	1120948.KB903219_gene697	9.703e-56	213.0	COG0177@1|root,COG0177@2|Bacteria,2GNYB@201174|Actinobacteria,4E30T@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_6987599_0	1120948.KB903219_gene693	0.0	1118.0	COG1807@1|root,COG1807@2|Bacteria,2GKH9@201174|Actinobacteria,4DYSK@85010|Pseudonocardiales	201174|Actinobacteria	M	Mycobacterial cell wall arabinan synthesis protein	-	-	-	ko:K11386	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Arabino_trans_C,Arabinose_trans
TLS3_k127_6991346_6	1120948.KB903223_gene256	7.45e-64	220.0	COG1028@1|root,COG1028@2|Bacteria,2GJIH@201174|Actinobacteria,4DXXW@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_6991346_2	1120948.KB903223_gene257	9.691e-99	325.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4E1RM@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA2	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
TLS3_k127_6991346_7	1120948.KB903223_gene258	3.863e-53	190.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4E4H7@85010|Pseudonocardiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iNJ661.Rv1826	GCV_H
TLS3_k127_6991346_5	1120948.KB903223_gene259	4.357e-77	267.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4E2ZJ@85010|Pseudonocardiales	201174|Actinobacteria	T	(FHA) domain	garA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
TLS3_k127_6991346_3	1120948.KB903223_gene260	8.168e-96	321.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4DY01@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM MerR family regulatory protein	merR1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
TLS3_k127_6991346_4	446462.Amir_5354	7.387e-87	289.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4DXJH@85010|Pseudonocardiales	201174|Actinobacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
TLS3_k127_6991346_1	1120948.KB903223_gene262	9.485e-101	333.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,4DZP8@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR2	-	-	-	-	-	-	-	-	-	-	-	MerR_1
TLS3_k127_6991346_0	1120948.KB903223_gene263	6.97e-322	993.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,4DXCZ@85010|Pseudonocardiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
TLS3_k127_6992468_4	356851.JOAN01000001_gene3537	7.139e-24	106.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4D8SX@85008|Micromonosporales	201174|Actinobacteria	V	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
TLS3_k127_6992468_2	1120948.KB903217_gene964	9.306e-46	168.0	COG3011@1|root,COG3011@2|Bacteria,2IMHW@201174|Actinobacteria,4E7H4@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
TLS3_k127_6992468_3	1120950.KB892708_gene4181	2.599e-28	129.0	COG2764@1|root,COG2764@2|Bacteria,2IFK2@201174|Actinobacteria,4DS2F@85009|Propionibacteriales	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_6992468_1	2074.JNYD01000007_gene2046	4.625e-66	237.0	COG2207@1|root,COG2207@2|Bacteria,2GK7C@201174|Actinobacteria,4E6XU@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
TLS3_k127_6992468_0	1120948.KB903217_gene963	3.339e-169	544.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria,4DXWP@85010|Pseudonocardiales	201174|Actinobacteria	P	flavoprotein involved in K transport	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,K_oxygenase,NAD_binding_8,Pyr_redox_2,Pyr_redox_3
TLS3_k127_6993293_0	1120948.KB903217_gene1001	5.11e-259	811.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4DXGQ@85010|Pseudonocardiales	201174|Actinobacteria	D	membrane	mviN	GO:0003674,GO:0005215,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
TLS3_k127_6993293_1	1120948.KB903217_gene1000	4.51e-202	647.0	COG0515@1|root,COG0515@2|Bacteria,2GM4A@201174|Actinobacteria,4DZGX@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
TLS3_k127_6993293_2	1121946.AUAX01000006_gene3373	3.081e-59	212.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4DD37@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
TLS3_k127_6993293_4	1120948.KB903217_gene997	1.988e-15	81.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4DZ54@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_6998414_0	1120948.KB903217_gene1030	1.751e-151	482.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,4DXUK@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
TLS3_k127_6998414_1	1123023.JIAI01000005_gene911	4.054e-90	310.0	COG0451@1|root,COG0451@2|Bacteria,2GMHH@201174|Actinobacteria,4E213@85010|Pseudonocardiales	201174|Actinobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	GO:0000166,GO:0003674,GO:0003824,GO:0003854,GO:0004769,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016020,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016853,GO:0016860,GO:0016863,GO:0030283,GO:0033764,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901360,GO:1901363	1.1.1.145,1.1.1.412,5.3.3.1	ko:K16045,ko:K22320	ko00984,ko01120,map00984,map01120	-	R09920	RC00146	ko00000,ko00001,ko01000	-	-	-	3Beta_HSD,Epimerase
TLS3_k127_6998414_3	1463825.JNXC01000022_gene603	8.162e-31	132.0	COG1324@1|root,COG1324@2|Bacteria,2IQF1@201174|Actinobacteria,4E5E3@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
TLS3_k127_6998414_2	1120948.KB903217_gene1026	1.349e-63	227.0	COG0477@1|root,COG2814@2|Bacteria,2GMWE@201174|Actinobacteria,4E0VX@85010|Pseudonocardiales	201174|Actinobacteria	EGP	PFAM Major Facilitator Superfamily	ynfM	-	-	ko:K08224	-	-	-	-	ko00000,ko02000	2.A.1.36	-	-	MFS_1,Sugar_tr
TLS3_k127_7001001_10	1828.JOKB01000009_gene5356	1.002e-34	147.0	COG3271@1|root,COG3271@2|Bacteria,2IQM7@201174|Actinobacteria,4G7A9@85025|Nocardiaceae	201174|Actinobacteria	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
TLS3_k127_7001001_9	909613.UO65_6412	1.27e-43	162.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria,4E5FV@85010|Pseudonocardiales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_7001001_7	1120948.KB903220_gene150	1.637e-66	254.0	COG2318@1|root,COG2318@2|Bacteria,2II1I@201174|Actinobacteria,4E426@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
TLS3_k127_7001001_1	1120948.KB903234_gene4750	6.427e-145	479.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria,4E51P@85010|Pseudonocardiales	201174|Actinobacteria	M	Sortase (surface protein transpeptidase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
TLS3_k127_7001001_0	1120948.KB903244_gene2834	3.999e-197	640.0	COG0558@1|root,COG0558@2|Bacteria,2I5BP@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf,Sulfatase
TLS3_k127_7001001_2	358823.DF19_06535	2.3e-123	411.0	COG1063@1|root,COG1063@2|Bacteria,2GKU2@201174|Actinobacteria	201174|Actinobacteria	E	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH_N
TLS3_k127_7001001_11	2074.JNYD01000008_gene1136	7.016e-27	112.0	COG2331@1|root,COG2331@2|Bacteria,2GR6C@201174|Actinobacteria,4E6SR@85010|Pseudonocardiales	201174|Actinobacteria	S	regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
TLS3_k127_7001001_8	208439.AJAP_32970	3.067e-53	197.0	COG0720@1|root,COG0720@2|Bacteria,2II5D@201174|Actinobacteria,4E3F7@85010|Pseudonocardiales	201174|Actinobacteria	H	6-pyruvoyl tetrahydropterin synthase	ptpS	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
TLS3_k127_7001001_12	2074.JNYD01000031_gene6550	2.173e-26	124.0	COG1376@1|root,COG1376@2|Bacteria,2IQZG@201174|Actinobacteria,4EF0S@85010|Pseudonocardiales	201174|Actinobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
TLS3_k127_7001001_3	1123024.AUII01000028_gene2515	3.933e-105	361.0	COG0438@1|root,COG0438@2|Bacteria,2GYA2@201174|Actinobacteria,4DYVK@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_7001001_4	1123024.AUII01000028_gene2516	5.359e-88	301.0	COG4106@1|root,COG4106@2|Bacteria,2I37U@201174|Actinobacteria,4E30P@85010|Pseudonocardiales	201174|Actinobacteria	S	trans-aconitate 2-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_7001001_6	1157637.KB892111_gene4236	8.277e-67	246.0	COG0392@1|root,COG0392@2|Bacteria,2GP8H@201174|Actinobacteria	201174|Actinobacteria	H	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
TLS3_k127_7001001_5	1123024.AUII01000028_gene2518	1.551e-68	252.0	COG0406@1|root,COG0406@2|Bacteria,2HRP2@201174|Actinobacteria,4EAZ6@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
TLS3_k127_7009526_0	1123023.JIAI01000009_gene1059	3.419e-147	473.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4DXVK@85010|Pseudonocardiales	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
TLS3_k127_7009526_1	1120948.KB903248_gene4268	9.364e-113	370.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4DZFD@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
TLS3_k127_7009526_2	1123023.JIAI01000009_gene1061	1.939e-64	238.0	COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4DXWG@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
TLS3_k127_7016954_4	1120948.KB903217_gene1124	1.534e-10	61.0	COG0316@1|root,COG0316@2|Bacteria,2GR0Z@201174|Actinobacteria,4E7G9@85010|Pseudonocardiales	201174|Actinobacteria	S	HesB YadR YfhF-family protein	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
TLS3_k127_7016954_2	1037409.BJ6T_49510	5.437e-66	246.0	COG3313@1|root,COG3313@2|Bacteria,1N66E@1224|Proteobacteria,2U1CQ@28211|Alphaproteobacteria,3JW6K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Fe-S protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1289
TLS3_k127_7016954_0	1120948.KB903217_gene1125	0.0	1510.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4DXKT@85010|Pseudonocardiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
TLS3_k127_7016954_1	235985.BBPN01000006_gene3641	8.463e-98	330.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,2NFVT@228398|Streptacidiphilus	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
TLS3_k127_7016954_3	1172188.KB911822_gene967	1.741e-15	78.0	COG0346@1|root,COG0346@2|Bacteria,2IMGZ@201174|Actinobacteria,4FH1I@85021|Intrasporangiaceae	201174|Actinobacteria	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_7017319_3	1120948.KB903217_gene910	1.325e-91	314.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4DXUJ@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
TLS3_k127_7017319_4	1137269.AZWL01000006_gene6833	8.749e-56	201.0	COG1309@1|root,COG1309@2|Bacteria,2GNR9@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_7017319_9	1463821.JOGR01000005_gene2947	5.313e-07	61.0	COG0346@1|root,COG0346@2|Bacteria,2HZ2X@201174|Actinobacteria,4F00K@85014|Glycomycetales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_7017319_7	426716.JOAJ01000005_gene2881	1.303e-27	115.0	COG0346@1|root,COG0346@2|Bacteria,2HGU6@201174|Actinobacteria,4G19V@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_7017319_5	298654.FraEuI1c_3997	2.049e-34	141.0	COG1670@1|root,COG1670@2|Bacteria,2I3SF@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_7017319_2	749927.AMED_3774	2.731e-95	329.0	COG2021@1|root,COG2197@1|root,COG2021@2|Bacteria,COG2197@2|Bacteria,2GN4Z@201174|Actinobacteria,4EBFJ@85010|Pseudonocardiales	201174|Actinobacteria	K	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,GerE
TLS3_k127_7017319_6	710696.Intca_0369	2.172e-32	132.0	COG0596@1|root,COG1506@1|root,COG3710@1|root,COG0596@2|Bacteria,COG1506@2|Bacteria,COG3710@2|Bacteria,2HASC@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
TLS3_k127_7017319_8	1238182.C882_0312	6.509e-08	60.0	COG1765@1|root,COG1765@2|Bacteria,1RBJN@1224|Proteobacteria,2VF54@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
TLS3_k127_7017319_10	189753.AXAS01000078_gene6581	1.179e-06	61.0	COG0654@1|root,COG0654@2|Bacteria,1QWT3@1224|Proteobacteria,2U2GE@28211|Alphaproteobacteria,3JZXS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
TLS3_k127_7017319_1	1120948.KB903217_gene909	5.73e-111	378.0	COG0494@1|root,COG0494@2|Bacteria,2I2N6@201174|Actinobacteria,4DZ6J@85010|Pseudonocardiales	201174|Actinobacteria	L	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_7017319_0	1120948.KB903217_gene908	7.162e-153	492.0	COG0438@1|root,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4DYH4@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferases group 1	pimA	GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
TLS3_k127_7019297_3	2074.JNYD01000008_gene1171	7.341e-238	748.0	COG0318@1|root,COG0318@2|Bacteria,2I9YS@201174|Actinobacteria,4DYNR@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_7019297_4	1499967.BAYZ01000103_gene3792	1.351e-80	280.0	COG1063@1|root,COG1063@2|Bacteria,2NQEY@2323|unclassified Bacteria	2|Bacteria	C	Zinc-binding dehydrogenase	yphC	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	iECW_1372.ECW_m2771,iWFL_1372.ECW_m2771	ADH_N,ADH_zinc_N
TLS3_k127_7019297_6	1184609.KILIM_005_01310	3.004e-40	156.0	COG1063@1|root,COG1063@2|Bacteria,2IA26@201174|Actinobacteria	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
TLS3_k127_7019297_2	1120948.KB903224_gene339	1.824e-245	762.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4DZXH@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K03761	-	-	-	-	ko00000,ko02000	2.A.1.6.2	-	-	MFS_1,Sugar_tr
TLS3_k127_7019297_5	1120948.KB903224_gene338	9.668e-71	241.0	COG3304@1|root,COG3304@2|Bacteria,2IKS5@201174|Actinobacteria,4E4CS@85010|Pseudonocardiales	201174|Actinobacteria	S	Inner membrane component domain	yccF	-	-	-	-	-	-	-	-	-	-	-	YccF
TLS3_k127_7019297_0	1120948.KB903224_gene337	9e-323	998.0	COG1061@1|root,COG1061@2|Bacteria,2GIR9@201174|Actinobacteria,4DZPK@85010|Pseudonocardiales	201174|Actinobacteria	L	Type III restriction enzyme, res subunit	ercc3	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
TLS3_k127_7019297_1	1120948.KB903224_gene336	1.093e-294	955.0	COG4251@1|root,COG5263@1|root,COG4251@2|Bacteria,COG5263@2|Bacteria,2GK6E@201174|Actinobacteria,4DX42@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
TLS3_k127_7023359_1	405948.SACE_2437	6.952e-15	88.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4DXNB@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
TLS3_k127_7023359_0	349521.HCH_06817	5.891e-26	122.0	COG0524@1|root,COG0524@2|Bacteria,1QTMT@1224|Proteobacteria,1S1JQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
TLS3_k127_7023359_2	1157638.KB892209_gene971	2.93e-06	54.0	COG0778@1|root,COG3467@1|root,COG0778@2|Bacteria,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria	201174|Actinobacteria	K	pyridoxamine 5-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	DUF1918,HTH_3,HTH_31,Pyridox_ox_2
TLS3_k127_7038830_7	1120948.KB903244_gene3058	1.063e-29	123.0	COG0454@1|root,COG0454@2|Bacteria,2I4CB@201174|Actinobacteria,4E3NG@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
TLS3_k127_7038830_3	1120948.KB903244_gene3057	1.964e-81	276.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria,4E2VK@85010|Pseudonocardiales	201174|Actinobacteria	P	Reversible hydration of carbon dioxide	can	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
TLS3_k127_7038830_5	1048339.KB913029_gene1805	2.485e-48	193.0	COG0685@1|root,COG0685@2|Bacteria,2IAS3@201174|Actinobacteria,4EUX3@85013|Frankiales	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR
TLS3_k127_7038830_6	1120948.KB903244_gene3056	1.74e-45	165.0	2BZ6B@1|root,336KR@2|Bacteria,2IQEV@201174|Actinobacteria,4E7D3@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7038830_0	1120948.KB903244_gene3055	1.464e-181	583.0	COG3214@1|root,COG3214@2|Bacteria,2GJM7@201174|Actinobacteria,4E01A@85010|Pseudonocardiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
TLS3_k127_7038830_1	1120948.KB903244_gene3045	1.824e-113	374.0	COG0583@1|root,COG0583@2|Bacteria,2GK13@201174|Actinobacteria,4DZR9@85010|Pseudonocardiales	201174|Actinobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS3_k127_7038830_2	1120948.KB903244_gene3044	4.608e-102	338.0	28HIR@1|root,2Z7U4@2|Bacteria,2GN2S@201174|Actinobacteria,4E2KI@85010|Pseudonocardiales	201174|Actinobacteria	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
TLS3_k127_7038830_4	1120948.KB903244_gene3043	6.586e-81	274.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4DZFB@85010|Pseudonocardiales	201174|Actinobacteria	C	Fumarate reductase flavoprotein C-term	sdhA	-	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
TLS3_k127_7044782_0	1120948.KB903244_gene2898	1.158e-309	954.0	COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,4DXNM@85010|Pseudonocardiales	201174|Actinobacteria	L	Type III restriction enzyme, res subunit	sdrA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ResIII
TLS3_k127_7044782_1	1120948.KB903244_gene2899	2.357e-41	153.0	2CAFG@1|root,32RRB@2|Bacteria,2IQ98@201174|Actinobacteria,4EEBC@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3039)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3039
TLS3_k127_7047407_2	1463825.JNXC01000017_gene6978	2.021e-175	572.0	COG1384@1|root,COG1384@2|Bacteria,2GJP1@201174|Actinobacteria,4DYDA@85010|Pseudonocardiales	201174|Actinobacteria	J	tRNA synthetases class I (K)	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
TLS3_k127_7047407_3	28042.GU90_18065	5.309e-122	403.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,4E0EH@85010|Pseudonocardiales	201174|Actinobacteria	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	odx	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
TLS3_k127_7047407_0	1120948.KB903245_gene3533	1.268e-206	654.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4DXBP@85010|Pseudonocardiales	201174|Actinobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
TLS3_k127_7047407_1	1120948.KB903245_gene3534	5.621e-176	556.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4DZG5@85010|Pseudonocardiales	201174|Actinobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase	serA	GO:0003674,GO:0003824,GO:0004617,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
TLS3_k127_7048791_0	1120948.KB903229_gene5280	9.852e-140	453.0	COG0438@1|root,COG0438@2|Bacteria,2I8FJ@201174|Actinobacteria,4EF27@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
TLS3_k127_7048791_2	1120948.KB903217_gene960	2.054e-110	366.0	COG0491@1|root,COG0491@2|Bacteria,2HYI4@201174|Actinobacteria,4ECH0@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_7048791_1	1120948.KB903229_gene5278	8.434e-118	388.0	COG0859@1|root,COG0859@2|Bacteria,2I90V@201174|Actinobacteria,4E85H@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
TLS3_k127_7064994_2	2074.JNYD01000003_gene3583	9.851e-28	124.0	COG2755@1|root,COG2755@2|Bacteria,2GRDF@201174|Actinobacteria,4E0R4@85010|Pseudonocardiales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase	-	GO:0003674,GO:0003824,GO:0004806,GO:0005575,GO:0005576,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0019433,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046461,GO:0046464,GO:0046486,GO:0046503,GO:0052689,GO:0071704,GO:1901575	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS3_k127_7064994_0	994479.GL877878_gene2908	1.61e-88	298.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4DZM2@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TLS3_k127_7064994_1	2074.JNYD01000007_gene2044	1.652e-42	160.0	COG3801@1|root,COG3801@2|Bacteria,2IQGZ@201174|Actinobacteria,4E52D@85010|Pseudonocardiales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
TLS3_k127_7065178_0	1120948.KB903240_gene4162	1.27e-200	627.0	COG0346@1|root,COG0346@2|Bacteria,2GKY9@201174|Actinobacteria,4E5XW@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K00446	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
TLS3_k127_7065178_1	1120948.KB903240_gene4163	1.2e-183	592.0	COG0406@1|root,COG0406@2|Bacteria,2IB0T@201174|Actinobacteria,4E956@85010|Pseudonocardiales	201174|Actinobacteria	G	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
TLS3_k127_7065178_2	1120948.KB903240_gene4164	1.123e-107	375.0	COG1414@1|root,COG1414@2|Bacteria,2GJAZ@201174|Actinobacteria,4E8Z7@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
TLS3_k127_7065178_3	1206731.BAGB01000041_gene8642	9.051e-63	220.0	COG1846@1|root,COG1846@2|Bacteria,2I3KG@201174|Actinobacteria,4G9RD@85025|Nocardiaceae	201174|Actinobacteria	K	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,MarR
TLS3_k127_7065178_4	1120948.KB903240_gene4172	6.251e-17	89.0	COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria,4E8PX@85010|Pseudonocardiales	201174|Actinobacteria	E	Methionine synthase	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	-
TLS3_k127_7097137_0	1120948.KB903247_gene4606	4.998e-119	396.0	COG2718@1|root,COG2718@2|Bacteria,2I2WH@201174|Actinobacteria,4EDNP@85010|Pseudonocardiales	201174|Actinobacteria	S	Iron-containing redox enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
TLS3_k127_7097137_2	1120948.KB903247_gene4605	2.824e-76	273.0	COG2890@1|root,COG2890@2|Bacteria,2IIBT@201174|Actinobacteria,4E3YE@85010|Pseudonocardiales	201174|Actinobacteria	J	PFAM methyltransferase small	prmC_1	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
TLS3_k127_7097137_1	1120948.KB903240_gene4189	1.204e-118	388.0	COG1808@1|root,COG1808@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
TLS3_k127_7103956_3	1120948.KB903244_gene3172	1.653e-143	460.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4EBET@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_7103956_5	1120948.KB903244_gene3171	4.019e-42	156.0	2CAUA@1|root,33DTE@2|Bacteria,2GSGF@201174|Actinobacteria,4E6HR@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2631
TLS3_k127_7103956_2	1120948.KB903244_gene3170	1.424e-170	543.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4DY4I@85010|Pseudonocardiales	201174|Actinobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2870c	DXPR_C,DXP_redisom_C,DXP_reductoisom
TLS3_k127_7103956_1	1120948.KB903244_gene3169	6.281e-189	599.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4DXAV@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Peptidase family M50	rip1	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
TLS3_k127_7103956_0	1120948.KB903244_gene3168	2.528e-230	730.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4DZX0@85010|Pseudonocardiales	201174|Actinobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
TLS3_k127_7103956_4	1120948.KB903244_gene3167	1.097e-129	424.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria,4DYGQ@85010|Pseudonocardiales	201174|Actinobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
TLS3_k127_7117780_4	2074.JNYD01000035_gene6692	1.514e-53	201.0	COG3885@1|root,COG3885@2|Bacteria,2GN3T@201174|Actinobacteria,4E3SC@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7117780_1	1120948.KB903244_gene2977	2.763e-130	430.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4DX5R@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
TLS3_k127_7117780_2	1120948.KB903244_gene2976	4.238e-97	325.0	COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria,4E06A@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
TLS3_k127_7117780_0	1120948.KB903244_gene2975	1.113e-235	739.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4DXMT@85010|Pseudonocardiales	201174|Actinobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
TLS3_k127_7117780_3	330084.JNYZ01000024_gene2444	3.673e-59	228.0	COG3386@1|root,COG3386@2|Bacteria,2GNAZ@201174|Actinobacteria,4DZHG@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7126488_3	1120948.KB903217_gene1481	1.34e-63	224.0	COG1859@1|root,COG1859@2|Bacteria,2HVJW@201174|Actinobacteria,4E3M5@85010|Pseudonocardiales	201174|Actinobacteria	J	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase	kptA	-	-	ko:K07559	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PTS_2-RNA
TLS3_k127_7126488_1	1278078.G419_15958	9.147e-101	348.0	COG0842@1|root,COG0842@2|Bacteria,2GJGH@201174|Actinobacteria,4FZWI@85025|Nocardiaceae	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
TLS3_k127_7126488_0	471853.Bcav_3883	5.772e-105	363.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
TLS3_k127_7126488_4	1713.JOFV01000003_gene1485	6.755e-47	178.0	COG1309@1|root,COG1309@2|Bacteria,2GQBQ@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
TLS3_k127_7126488_2	2074.JNYD01000013_gene6823	1.354e-91	322.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4DYU2@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	ko:K21035	-	-	-	-	ko00000,ko00199	-	-	-	p450
TLS3_k127_7130601_3	1120948.KB903240_gene3871	7.126e-137	442.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4DZXW@85010|Pseudonocardiales	201174|Actinobacteria	S	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	egtB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
TLS3_k127_7130601_2	1120948.KB903240_gene3872	2.004e-156	509.0	COG3572@1|root,COG3572@2|Bacteria,2GJPI@201174|Actinobacteria,4DZ5S@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine	egtA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
TLS3_k127_7130601_0	1120948.KB903240_gene3873	1.382e-290	903.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4E01V@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS3_k127_7130601_6	1120948.KB903240_gene3874	1.312e-30	128.0	2E4I7@1|root,32ZDA@2|Bacteria,2IQBB@201174|Actinobacteria,4E5H2@85010|Pseudonocardiales	201174|Actinobacteria	S	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7130601_1	1120948.KB903240_gene3875	5.651e-284	907.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4E0E8@85010|Pseudonocardiales	201174|Actinobacteria	S	of ABC transporters with duplicated ATPase	ybiT	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn,DLIC
TLS3_k127_7130601_4	2074.JNYD01000001_gene6025	2.324e-106	350.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,4DY07@85010|Pseudonocardiales	201174|Actinobacteria	IQ	PFAM short chain dehydrogenase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_7130601_5	1120948.KB903240_gene3876	5.43e-48	176.0	2E6TR@1|root,331DK@2|Bacteria,2IQF8@201174|Actinobacteria,4E5HD@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7130601_7	2074.JNYD01000001_gene6024	1.76e-23	108.0	COG0644@1|root,COG0644@2|Bacteria,2GNH7@201174|Actinobacteria,4DYNV@85010|Pseudonocardiales	201174|Actinobacteria	C	Lycopene cyclase protein	crtL	-	5.5.1.19	ko:K06443	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R03824,R04801,R05341,R06962,R07856	RC01004,RC01964	ko00000,ko00001,ko00002,ko01000	-	-	-	Lycopene_cycl
TLS3_k127_7158718_0	1123023.JIAI01000002_gene5224	8.098e-136	458.0	COG0642@1|root,COG2205@2|Bacteria,2GK7K@201174|Actinobacteria,4DY4A@85010|Pseudonocardiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_7158718_3	345341.KUTG_07275	2.781e-90	303.0	COG0745@1|root,COG0745@2|Bacteria,2GKJK@201174|Actinobacteria,4DXGP@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_7158718_2	882086.SacxiDRAFT_3437	2.081e-121	394.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4DZ9D@85010|Pseudonocardiales	201174|Actinobacteria	E	ABC-type polar amino acid transport system, ATPase component	gluA	-	-	ko:K10008	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.9	-	-	ABC_tran
TLS3_k127_7158718_1	2074.JNYD01000035_gene6705	4.416e-126	409.0	COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,4DY03@85010|Pseudonocardiales	201174|Actinobacteria	ET	PFAM Bacterial extracellular solute-binding proteins, family 3	gluB1	-	-	ko:K10005	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	SBP_bac_3
TLS3_k127_7166225_7	1120948.KB903247_gene4476	2.064e-30	123.0	COG1032@1|root,COG1032@2|Bacteria,2GJY1@201174|Actinobacteria,4DXFP@85010|Pseudonocardiales	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
TLS3_k127_7166225_9	285535.JOEY01000043_gene1250	1.889e-08	67.0	COG0156@1|root,COG5001@1|root,COG0156@2|Bacteria,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,EAL,GGDEF,PAS,PAS_4,PAS_8,PAS_9
TLS3_k127_7166225_5	1120948.KB903247_gene4474	5.68e-65	228.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4E3I2@85010|Pseudonocardiales	201174|Actinobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	iNJ661.Rv2445c	NDK
TLS3_k127_7166225_6	1120948.KB903247_gene4472	9.035e-32	140.0	2DAVQ@1|root,32TW9@2|Bacteria,2GR36@201174|Actinobacteria,4E4S5@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF4233)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4233
TLS3_k127_7166225_0	1120948.KB903247_gene4471	1.636e-233	736.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4DXFC@85010|Pseudonocardiales	201174|Actinobacteria	H	PFAM Mur ligase family, glutamate ligase domain	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2447c	Mur_ligase_C,Mur_ligase_M
TLS3_k127_7166225_8	1123024.AUII01000008_gene1795	1.373e-13	74.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
TLS3_k127_7166225_1	1120948.KB903247_gene4469	9.937e-216	678.0	COG2223@1|root,COG2223@2|Bacteria,2I2RR@201174|Actinobacteria,4DZGQ@85010|Pseudonocardiales	201174|Actinobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
TLS3_k127_7166225_2	1120948.KB903247_gene4468	1.007e-132	428.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4DXH8@85010|Pseudonocardiales	201174|Actinobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
TLS3_k127_7166225_3	1120948.KB903247_gene4467	4.305e-105	349.0	COG0627@1|root,COG0627@2|Bacteria,2GKNS@201174|Actinobacteria,4E1YR@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
TLS3_k127_7166225_4	1120948.KB903247_gene4466	3.661e-103	336.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4DYXZ@85010|Pseudonocardiales	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
TLS3_k127_7166414_2	1120948.KB903217_gene893	1.362e-76	262.0	COG1940@1|root,COG1940@2|Bacteria,2GJ2S@201174|Actinobacteria,4E1VA@85010|Pseudonocardiales	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
TLS3_k127_7166414_1	1120948.KB903217_gene894	1.155e-99	332.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria,4EAVY@85010|Pseudonocardiales	201174|Actinobacteria	G	Trehalose-phosphatase	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
TLS3_k127_7166414_0	1120948.KB903217_gene895	9.17e-122	396.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,4E01Z@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
TLS3_k127_7182356_12	1120948.KB903229_gene5157	4.258e-09	59.0	COG0596@1|root,COG0596@2|Bacteria,2I3PB@201174|Actinobacteria,4EF6P@85010|Pseudonocardiales	201174|Actinobacteria	S	Serine aminopeptidase, S33	pcaD	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
TLS3_k127_7182356_8	1120948.KB903229_gene5158	1.274e-50	181.0	COG4829@1|root,COG4829@2|Bacteria,2IQZJ@201174|Actinobacteria,4E5DX@85010|Pseudonocardiales	201174|Actinobacteria	Q	muconolactone delta-isomerase	catC	-	5.3.3.4	ko:K03464	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R06990	RC01109	ko00000,ko00001,ko00002,ko01000	-	-	-	MIase
TLS3_k127_7182356_2	1120948.KB903229_gene5159	1.152e-189	615.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4E1HK@85010|Pseudonocardiales	201174|Actinobacteria	M	Mandelate racemase muconate lactonizing enzyme	catB	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
TLS3_k127_7182356_5	1120948.KB903229_gene5160	2.412e-119	391.0	COG0583@1|root,COG0583@2|Bacteria,2GK13@201174|Actinobacteria,4E2GN@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS3_k127_7182356_3	1120948.KB903229_gene5161	1.849e-165	539.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria,4DY31@85010|Pseudonocardiales	201174|Actinobacteria	Q	PFAM Intradiol ring-cleavage dioxygenase, C-terminal	-	-	1.13.11.1	ko:K03381	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
TLS3_k127_7182356_7	1120948.KB903229_gene5162	5.288e-69	256.0	COG0654@1|root,COG0654@2|Bacteria,2GIZU@201174|Actinobacteria,4E1JY@85010|Pseudonocardiales	201174|Actinobacteria	CH	FAD binding domain	-	-	1.14.13.1	ko:K00480	ko00621,ko00624,ko00626,ko01100,ko01120,ko01220,map00621,map00624,map00626,map01100,map01120,map01220	-	R00818,R05632,R06915,R06936,R06939	RC00389	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
TLS3_k127_7182356_6	1120948.KB903229_gene5166	4.74e-70	249.0	COG1853@1|root,COG1853@2|Bacteria,2GPJS@201174|Actinobacteria,4E4JG@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM flavin reductase	hsaB	-	-	ko:K16048	ko00984,ko01100,map00984,map01100	-	R09819	RC00236	ko00000,ko00001,ko01000	-	-	-	Flavin_Reduct
TLS3_k127_7182356_1	2074.JNYD01000025_gene576	9.724e-209	665.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4DZ1Z@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
TLS3_k127_7182356_9	1120948.KB903229_gene5173	3.846e-43	168.0	COG2867@1|root,COG2867@2|Bacteria	2|Bacteria	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2,START
TLS3_k127_7182356_10	1380393.JHVP01000010_gene3017	1.393e-25	112.0	COG4338@1|root,COG4338@2|Bacteria,2GQT9@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3253)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2256,DUF3253
TLS3_k127_7182356_4	1120948.KB903229_gene5172	1.152e-146	472.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,4DYGY@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
TLS3_k127_7182356_13	1449976.KALB_7981	3.487e-05	52.0	2AE55@1|root,313YJ@2|Bacteria,2HDK6@201174|Actinobacteria,4ED1Z@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7182356_0	1120948.KB903217_gene1706	2.855e-272	848.0	COG3573@1|root,COG3573@2|Bacteria,2GIYM@201174|Actinobacteria,4DYE0@85010|Pseudonocardiales	201174|Actinobacteria	S	FAD binding domain	-	-	-	ko:K07077	-	-	-	-	ko00000	-	-	-	FAD_binding_2
TLS3_k127_7182356_11	1120948.KB903229_gene5175	1.549e-13	70.0	COG3583@1|root,COG3583@2|Bacteria,2I5N9@201174|Actinobacteria	201174|Actinobacteria	S	Transglycosylase-like domain	-	-	-	ko:K21687	-	-	-	-	ko00000	-	GH23	-	Transglycosylas
TLS3_k127_7195230_3	1120948.KB903217_gene1138	6.682e-39	146.0	COG0666@1|root,COG0666@2|Bacteria,2IIAC@201174|Actinobacteria,4E4DI@85010|Pseudonocardiales	201174|Actinobacteria	S	Ankyrin repeat-containing protein	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4,Ank_5
TLS3_k127_7195230_0	1120948.KB903217_gene1133	4.215e-256	803.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4DX5F@85010|Pseudonocardiales	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
TLS3_k127_7195230_1	1120948.KB903217_gene1132	4.694e-225	707.0	COG3288@1|root,COG3288@2|Bacteria,2I2FZ@201174|Actinobacteria,4DX8X@85010|Pseudonocardiales	201174|Actinobacteria	C	NAD NADP transhydrogenase alpha subunit	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
TLS3_k127_7195230_2	479435.Kfla_6934	5.746e-126	422.0	COG2141@1|root,COG2141@2|Bacteria,2GJ66@201174|Actinobacteria,4DPN9@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_7195230_4	457425.XNR_1191	1.174e-07	57.0	COG3154@1|root,COG3154@2|Bacteria,2I3CY@201174|Actinobacteria	201174|Actinobacteria	I	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
TLS3_k127_7230105_0	1206741.BAFX01000183_gene7611	6.377e-217	696.0	COG5360@1|root,COG5360@2|Bacteria,2GX24@201174|Actinobacteria	201174|Actinobacteria	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
TLS3_k127_7235126_0	1120948.KB903217_gene1149	2.722e-168	537.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,4DZB3@85010|Pseudonocardiales	201174|Actinobacteria	S	peptidase U62 modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
TLS3_k127_7235126_1	1120948.KB903217_gene1151	9.203e-65	232.0	COG0699@1|root,COG0699@2|Bacteria,2GNGP@201174|Actinobacteria,4DYJS@85010|Pseudonocardiales	201174|Actinobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
TLS3_k127_7240961_0	1120948.KB903247_gene4463	1.743e-204	649.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4DXJ2@85010|Pseudonocardiales	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
TLS3_k127_7240961_3	1380347.JNII01000005_gene3016	5.727e-71	252.0	COG1357@1|root,COG1357@2|Bacteria,2GM3W@201174|Actinobacteria,4EUFF@85013|Frankiales	201174|Actinobacteria	S	Pentapeptide repeats (8 copies)	yybG	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
TLS3_k127_7240961_4	1197706.AKKK01000003_gene38	7.431e-51	183.0	COG1742@1|root,COG1742@2|Bacteria,2IKM8@201174|Actinobacteria	201174|Actinobacteria	K	UPF0060 membrane protein	-	-	-	ko:K09771	-	-	-	-	ko00000,ko02000	2.A.7.26	-	-	UPF0060
TLS3_k127_7240961_7	1968.JOEV01000025_gene5318	6.107e-27	114.0	2E49F@1|root,32Z57@2|Bacteria,2IKMB@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4180)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4180
TLS3_k127_7240961_5	1125971.ASJB01000030_gene1056	4.511e-39	152.0	COG2261@1|root,COG2261@2|Bacteria,2GS37@201174|Actinobacteria,4ECPS@85010|Pseudonocardiales	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
TLS3_k127_7240961_6	1120948.KB903247_gene4631	1.67e-28	132.0	COG1426@1|root,COG1426@2|Bacteria,2IQH6@201174|Actinobacteria,4E6H9@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
TLS3_k127_7240961_1	1120948.KB903247_gene4632	6.653e-112	372.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4DY9S@85010|Pseudonocardiales	201174|Actinobacteria	E	methionine	map_2	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
TLS3_k127_7240961_2	2074.JNYD01000015_gene4478	2.203e-93	333.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2GKEF@201174|Actinobacteria,4E9SI@85010|Pseudonocardiales	201174|Actinobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,SpoIIE
TLS3_k127_7264361_1	1713.JOFV01000021_gene1290	0.0	1180.0	COG3119@1|root,COG3119@2|Bacteria,2HEHP@201174|Actinobacteria,4F2XG@85016|Cellulomonadaceae	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
TLS3_k127_7264361_15	675635.Psed_4258	1.154e-09	62.0	291WA@1|root,2ZPG1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7264361_13	1463825.JNXC01000007_gene917	7.534e-33	136.0	COG1573@1|root,COG1573@2|Bacteria,2IN4U@201174|Actinobacteria,4EF09@85010|Pseudonocardiales	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
TLS3_k127_7264361_2	1120948.KB903223_gene177	2.706e-268	835.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DX8B@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_7264361_16	67352.JODS01000005_gene6152	3.515e-06	57.0	COG1765@1|root,COG1765@2|Bacteria,2IIKU@201174|Actinobacteria	201174|Actinobacteria	O	OsmC-like protein	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
TLS3_k127_7264361_14	1219581.HMPREF1628_01165	3.367e-29	119.0	2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria,4D61Z@85005|Actinomycetales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB3	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
TLS3_k127_7264361_8	258052.JNYV01000009_gene3428	1.11e-65	241.0	COG1075@1|root,COG1075@2|Bacteria,2GJGC@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_7264361_17	1090318.ATTI01000001_gene3285	2.26e-05	53.0	COG2388@1|root,COG2388@2|Bacteria,1N8AQ@1224|Proteobacteria,2UFVS@28211|Alphaproteobacteria,2K5XE@204457|Sphingomonadales	204457|Sphingomonadales	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
TLS3_k127_7264361_9	1206731.BAGB01000166_gene846	1.652e-54	209.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria,4G0SU@85025|Nocardiaceae	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
TLS3_k127_7264361_3	1120948.KB903221_gene515	6.54e-136	441.0	COG0702@1|root,COG0702@2|Bacteria,2GJB8@201174|Actinobacteria,4DZ9W@85010|Pseudonocardiales	201174|Actinobacteria	GM	NmrA-like family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10,NmrA
TLS3_k127_7264361_5	1343740.M271_00515	4.531e-95	321.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
TLS3_k127_7264361_4	1123023.JIAI01000008_gene1401	3.229e-101	338.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4E1AV@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.149,4.2.1.17	ko:K01692,ko:K08299	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093,R10675	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
TLS3_k127_7264361_6	1120948.KB903243_gene2475	3.367e-82	278.0	COG0346@1|root,COG0346@2|Bacteria,2HKRN@201174|Actinobacteria,4E2WG@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
TLS3_k127_7264361_11	1120948.KB903240_gene4077	1.172e-40	157.0	COG0640@1|root,COG0640@2|Bacteria,2IM0G@201174|Actinobacteria,4E4U4@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K22298	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
TLS3_k127_7264361_7	1120948.KB903240_gene4078	1.189e-79	280.0	COG1063@1|root,COG1063@2|Bacteria,2GPPT@201174|Actinobacteria	201174|Actinobacteria	E	Nicotianamine synthase protein	-	-	-	-	-	-	-	-	-	-	-	-	NAS
TLS3_k127_7264361_12	1120948.KB903240_gene4128	3.289e-39	163.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	AhpC-TSA,CarboxypepD_reg,Plug,TonB_dep_Rec
TLS3_k127_7264361_0	675635.Psed_1573	0.0	1241.0	COG0845@1|root,COG4770@1|root,COG4799@1|root,COG0845@2|Bacteria,COG4770@2|Bacteria,COG4799@2|Bacteria,2GIZP@201174|Actinobacteria,4DZJ9@85010|Pseudonocardiales	201174|Actinobacteria	I	Acetyl propionyl-CoA carboxylase, alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	ACC_central,Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
TLS3_k127_7265609_12	1123320.KB889749_gene4533	7.436e-43	167.0	2CT9V@1|root,32SSX@2|Bacteria,2GKR6@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
TLS3_k127_7265609_7	1120948.KB903240_gene3834	2.967e-72	268.0	COG5180@1|root,COG5180@2|Bacteria,2GKJ7@201174|Actinobacteria,4E186@85010|Pseudonocardiales	201174|Actinobacteria	A	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
TLS3_k127_7265609_10	1120948.KB903240_gene3835	5.896e-64	229.0	COG3554@1|root,COG3554@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09957	-	-	-	-	ko00000	-	-	-	Glycolipid_bind
TLS3_k127_7265609_9	1120948.KB903240_gene3836	1.209e-65	248.0	COG0398@1|root,COG0398@2|Bacteria,2GN68@201174|Actinobacteria,4E3CB@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM SNARE associated Golgi protein	ydjZ	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
TLS3_k127_7265609_6	1121019.AUMN01000002_gene145	1.717e-94	316.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_7265609_2	1120948.KB903240_gene3838	1.555e-227	716.0	COG1233@1|root,COG3349@1|root,COG1233@2|Bacteria,COG3349@2|Bacteria,2GITE@201174|Actinobacteria,4DX5N@85010|Pseudonocardiales	201174|Actinobacteria	Q	PFAM Flavin containing amine oxidoreductase	crtU	-	-	ko:K09879	ko00906,map00906	-	R07541,R07560,R07857,R07858	RC01901,RC01965	ko00000,ko00001	-	-	-	Amino_oxidase
TLS3_k127_7265609_1	1120948.KB903240_gene3840	1.293e-279	865.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DYJK@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_7265609_8	1122611.KB903968_gene2311	4.314e-67	246.0	COG0454@1|root,COG0454@2|Bacteria,2HX8M@201174|Actinobacteria,4EI16@85012|Streptosporangiales	201174|Actinobacteria	K	Protein of unknown function (DUF3616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616
TLS3_k127_7265609_11	1211815.CBYP010000024_gene1522	3.214e-61	243.0	COG1073@1|root,COG1073@2|Bacteria,2I364@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
TLS3_k127_7265609_0	1120948.KB903240_gene3845	1.245e-284	882.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4E0NK@85010|Pseudonocardiales	201174|Actinobacteria	J	tRNA synthetases class I (E and Q), catalytic domain	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
TLS3_k127_7265609_3	1120948.KB903240_gene3846	1.751e-185	588.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4DY3Q@85010|Pseudonocardiales	201174|Actinobacteria	O	SPFH domain Band 7 family	hflK	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
TLS3_k127_7265609_13	1120948.KB903240_gene3847	1.688e-36	155.0	COG1585@1|root,COG1585@2|Bacteria,2IHZU@201174|Actinobacteria,4E5GI@85010|Pseudonocardiales	201174|Actinobacteria	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
TLS3_k127_7265609_4	1120948.KB903240_gene3848	2.942e-142	475.0	COG0613@1|root,COG0613@2|Bacteria,2GIZ5@201174|Actinobacteria,4DYF1@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3097)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3097
TLS3_k127_7265609_5	1120948.KB903240_gene3849	5.685e-107	370.0	2BK9Y@1|root,32EQ4@2|Bacteria,2GMZH@201174|Actinobacteria,4E2SM@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7277817_0	1123024.AUII01000046_gene3919	3.5e-284	880.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4E00A@85010|Pseudonocardiales	201174|Actinobacteria	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
TLS3_k127_7277817_2	43354.JOIJ01000012_gene950	2.356e-104	352.0	COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria,4DYVV@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
TLS3_k127_7277817_1	1380393.JHVP01000005_gene3667	5.443e-118	393.0	COG4987@1|root,COG4988@1|root,COG4987@2|Bacteria,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria,4ES5G@85013|Frankiales	201174|Actinobacteria	V	TIGRFAM ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein	cydD	-	-	ko:K16013,ko:K16014	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
TLS3_k127_7327637_2	1392838.AWNM01000019_gene4059	1.438e-15	83.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	ko:K05555	ko01057,ko01130,map01057,map01130	M00778	R09305	-	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	Lactamase_B
TLS3_k127_7327637_1	479431.Namu_2007	3.57e-23	107.0	2DPV0@1|root,333GV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7327637_0	1429046.RR21198_4923	9.321e-42	164.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4G1Y6@85025|Nocardiaceae	201174|Actinobacteria	I	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,PAP2_3,WES_acyltransf
TLS3_k127_7354494_1	1172185.KB911509_gene275	2.826e-16	81.0	arCOG10154@1|root,3068I@2|Bacteria,2IKV1@201174|Actinobacteria,4G1MR@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7354494_2	1385518.N798_00660	8.209e-13	72.0	arCOG10154@1|root,3068I@2|Bacteria,2IKV1@201174|Actinobacteria,4FH7P@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7354494_0	1120948.KB903218_gene1871	4.527e-184	578.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4DY68@85010|Pseudonocardiales	201174|Actinobacteria	C	FAD linked	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
TLS3_k127_7371859_0	1123024.AUII01000027_gene2616	2.942e-135	460.0	COG0477@1|root,COG0477@2|Bacteria,2GKVX@201174|Actinobacteria,4EAZV@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_7371859_1	1120948.KB903240_gene3790	1.295e-95	325.0	COG3266@1|root,COG3266@2|Bacteria,2GP1Z@201174|Actinobacteria,4DZQN@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM type VII secretion protein EccB, Actinobacterial	eccB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	T7SS_ESX1_EccB
TLS3_k127_7374678_2	1386089.N865_11170	3.886e-56	199.0	COG2197@1|root,COG2197@2|Bacteria,2IFE7@201174|Actinobacteria,4FJ1Z@85021|Intrasporangiaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_7374678_0	526225.Gobs_0116	0.0	1664.0	COG0642@1|root,COG0745@1|root,COG1366@1|root,COG2172@1|root,COG2203@1|root,COG2208@1|root,COG0745@2|Bacteria,COG1366@2|Bacteria,COG2172@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria,4ERBM@85013|Frankiales	201174|Actinobacteria	T	protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA,PAS_3,PAS_4,Response_reg,STAS_2,SpoIIE
TLS3_k127_7374678_1	1120948.KB903218_gene2193	4.888e-275	887.0	COG0296@1|root,COG0296@2|Bacteria,2GMIS@201174|Actinobacteria,4DXQU@85010|Pseudonocardiales	201174|Actinobacteria	G	Domain of unknown function (DUF3459)	treZ	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016787,GO:0016798,GO:0030978,GO:0030980,GO:0033942,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0071704,GO:1901575,GO:1901576	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
TLS3_k127_7374678_3	1120948.KB903232_gene4668	4.519e-54	199.0	COG2518@1|root,COG2518@2|Bacteria,2GJ3I@201174|Actinobacteria,4E63Q@85010|Pseudonocardiales	201174|Actinobacteria	O	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
TLS3_k127_7374678_5	744872.Spica_2820	1.796e-11	74.0	2C6Z5@1|root,32RI1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7374678_4	266940.Krad_3363	2.342e-15	79.0	COG1832@1|root,COG1832@2|Bacteria,2IHSP@201174|Actinobacteria	201174|Actinobacteria	S	CoA-binding	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
TLS3_k127_7380765_5	2074.JNYD01000003_gene3923	4.152e-55	195.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,4DYKX@85010|Pseudonocardiales	201174|Actinobacteria	C	luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_7380765_4	2074.JNYD01000003_gene3922	1.287e-60	213.0	COG1846@1|root,COG1846@2|Bacteria,2GP6A@201174|Actinobacteria,4E4U7@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
TLS3_k127_7380765_0	1120948.KB903243_gene2716	1.714e-255	797.0	COG0654@1|root,COG0654@2|Bacteria,2GN2W@201174|Actinobacteria,4E0C5@85010|Pseudonocardiales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ABM,FAD_binding_3
TLS3_k127_7380765_1	2074.JNYD01000046_gene7306	1.017e-203	647.0	COG0397@1|root,COG0397@2|Bacteria,2GNRX@201174|Actinobacteria,4E0WE@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
TLS3_k127_7380765_3	2074.JNYD01000030_gene6598	7.408e-91	302.0	2A4DI@1|root,30SZC@2|Bacteria,2GJJM@201174|Actinobacteria,4EAHG@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7380765_2	1120948.KB903217_gene890	6.181e-93	321.0	COG0657@1|root,COG0657@2|Bacteria,2GTEV@201174|Actinobacteria,4E518@85010|Pseudonocardiales	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
TLS3_k127_7383707_7	1169161.KB897737_gene2401	1.573e-98	324.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
TLS3_k127_7383707_3	1120948.KB903217_gene1163	2.524e-295	917.0	COG2199@1|root,COG3706@2|Bacteria,2I412@201174|Actinobacteria,4EDSF@85010|Pseudonocardiales	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
TLS3_k127_7383707_15	1120948.KB903217_gene1162	1.645e-26	117.0	COG0381@1|root,COG0381@2|Bacteria,2GJWS@201174|Actinobacteria,4E7ZX@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
TLS3_k127_7383707_12	675635.Psed_2531	2.595e-35	151.0	COG3945@1|root,COG3945@2|Bacteria,2I6SN@201174|Actinobacteria	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
TLS3_k127_7383707_13	1440774.Y900_021360	4.007e-30	135.0	COG3945@1|root,COG3945@2|Bacteria,2IC3R@201174|Actinobacteria,2341U@1762|Mycobacteriaceae	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
TLS3_k127_7383707_6	1120948.KB903220_gene91	1.362e-98	333.0	COG1802@1|root,COG1802@2|Bacteria,2H1S8@201174|Actinobacteria,4E6KA@85010|Pseudonocardiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
TLS3_k127_7383707_2	1120948.KB903220_gene92	5.901e-301	931.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4DXB8@85010|Pseudonocardiales	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TLS3_k127_7383707_5	1120948.KB903220_gene93	5.934e-274	868.0	COG1541@1|root,COG1541@2|Bacteria,2GJC7@201174|Actinobacteria,4E0UM@85010|Pseudonocardiales	201174|Actinobacteria	H	AMP-binding enzyme C-terminal domain	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
TLS3_k127_7383707_4	1120948.KB903220_gene94	8.421e-282	871.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DX8B@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.98	ko:K20928	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
TLS3_k127_7383707_9	1120948.KB903220_gene95	9.975e-95	314.0	2A7QB@1|root,30WP1@2|Bacteria,2IJVB@201174|Actinobacteria,4ECSD@85010|Pseudonocardiales	201174|Actinobacteria	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
TLS3_k127_7383707_0	1120948.KB903220_gene96	0.0	1055.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria,4E1GQ@85010|Pseudonocardiales	201174|Actinobacteria	E	GMC oxidoreductase	-	-	1.1.1.400	ko:K20927	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
TLS3_k127_7383707_11	235985.BBPN01000009_gene3710	3.17e-36	143.0	COG5496@1|root,COG5496@2|Bacteria,2IKZP@201174|Actinobacteria,2NMSU@228398|Streptacidiphilus	201174|Actinobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
TLS3_k127_7383707_1	1120948.KB903220_gene100	0.0	1009.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4DXHS@85010|Pseudonocardiales	201174|Actinobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
TLS3_k127_7383707_10	1120948.KB903220_gene101	7.227e-51	202.0	COG0776@1|root,COG0776@2|Bacteria,2IKW5@201174|Actinobacteria,4E50H@85010|Pseudonocardiales	201174|Actinobacteria	L	regulation of translation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7383707_8	1089545.KB913037_gene7765	6.944e-96	323.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria,4DX9S@85010|Pseudonocardiales	201174|Actinobacteria	S	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate	tam	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0051704	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25
TLS3_k127_7383707_16	1120948.KB903220_gene105	4.72e-23	104.0	2DRKZ@1|root,33C8D@2|Bacteria,2I1C6@201174|Actinobacteria,4E73U@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7383707_14	208444.JNYY01000001_gene5505	3.311e-27	122.0	2EF7F@1|root,3390F@2|Bacteria,2GR4B@201174|Actinobacteria,4ECKF@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7383707_18	749927.AMED_4457	9.202e-05	45.0	2DT0R@1|root,33I6N@2|Bacteria,2H0DK@201174|Actinobacteria,4EB99@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7393730_3	1120948.KB903218_gene2072	5.634e-21	102.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4E32T@85010|Pseudonocardiales	201174|Actinobacteria	L	HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH
TLS3_k127_7393730_6	596319.STAWA0001_2387	3.393e-10	66.0	COG1846@1|root,COG1846@2|Bacteria,1V8TC@1239|Firmicutes,4HK9G@91061|Bacilli	91061|Bacilli	K	MarR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
TLS3_k127_7393730_0	1120948.KB903246_gene3344	2.218e-85	303.0	COG0477@1|root,COG2814@2|Bacteria,2HRV9@201174|Actinobacteria,4E1KT@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Arabinose efflux permease family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_7393730_2	1120948.KB903246_gene3343	4.133e-30	124.0	COG2154@1|root,COG2154@2|Bacteria,2IKXR@201174|Actinobacteria,4E5XU@85010|Pseudonocardiales	201174|Actinobacteria	H	PFAM Pterin 4 alpha carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
TLS3_k127_7393730_5	1122609.AUGT01000006_gene1486	4.818e-13	70.0	COG1051@1|root,COG1051@2|Bacteria,2IQEA@201174|Actinobacteria,4DSDJ@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	mutT2	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
TLS3_k127_7413846_15	298655.KI912267_gene7025	6.912e-09	59.0	2EUDF@1|root,33MVU@2|Bacteria,2IQFI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7413846_3	1177594.MIC448_1110022	2.985e-132	432.0	COG1253@1|root,COG1253@2|Bacteria,2GJ8X@201174|Actinobacteria,4FQZ9@85023|Microbacteriaceae	201174|Actinobacteria	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
TLS3_k127_7413846_0	1177594.MIC448_1110021	5.879e-194	615.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4FMPE@85023|Microbacteriaceae	201174|Actinobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
TLS3_k127_7413846_7	1123024.AUII01000052_gene3914	4.394e-87	291.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4EEKA@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
TLS3_k127_7413846_8	1120948.KB903243_gene2450	2.311e-56	202.0	COG3467@1|root,COG3467@2|Bacteria,2IG17@201174|Actinobacteria,4E5M4@85010|Pseudonocardiales	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
TLS3_k127_7413846_4	1120948.KB903229_gene5249	1.219e-128	428.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4DYPQ@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	cbiO	-	-	ko:K02006,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
TLS3_k127_7413846_5	1120948.KB903229_gene5250	4.576e-104	351.0	COG0619@1|root,COG0619@2|Bacteria,2GKQ7@201174|Actinobacteria,4E0T6@85010|Pseudonocardiales	201174|Actinobacteria	P	Cobalt transport protein	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
TLS3_k127_7413846_12	1120948.KB903229_gene5251	9.118e-27	127.0	COG0310@1|root,COG0310@2|Bacteria,2IS99@201174|Actinobacteria,4E702@85010|Pseudonocardiales	201174|Actinobacteria	P	PDGLE domain	-	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	PDGLE
TLS3_k127_7413846_6	1120948.KB903229_gene5252	1.103e-102	338.0	COG0310@1|root,COG0310@2|Bacteria,2GK2U@201174|Actinobacteria,4DZUB@85010|Pseudonocardiales	201174|Actinobacteria	P	Cobalt uptake substrate-specific transmembrane region	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
TLS3_k127_7413846_11	1463857.JOFZ01000001_gene5501	7.377e-43	165.0	COG1309@1|root,COG1309@2|Bacteria,2IIM0@201174|Actinobacteria	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
TLS3_k127_7413846_1	1120948.KB903229_gene5254	2.344e-156	505.0	COG0654@1|root,COG0654@2|Bacteria,2GXK6@201174|Actinobacteria,4DYEH@85010|Pseudonocardiales	201174|Actinobacteria	CH	PFAM FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
TLS3_k127_7413846_9	1120948.KB903229_gene5255	3.792e-50	183.0	COG0346@1|root,COG0346@2|Bacteria,2GQZ9@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_7413846_10	1120948.KB903229_gene5256	7.723e-44	161.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4DX5K@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
TLS3_k127_7413846_2	1120948.KB903229_gene5256	5.036e-135	447.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4DX5K@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
TLS3_k127_7413846_13	1120948.KB903229_gene5257	6.968e-13	76.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4DZYY@85010|Pseudonocardiales	201174|Actinobacteria	HQ	isochorismate	-	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
TLS3_k127_7419791_2	1120948.KB903244_gene3006	7.976e-28	116.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,4E0VJ@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	allR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
TLS3_k127_7419791_1	2074.JNYD01000012_gene376	9.083e-143	487.0	COG2234@1|root,COG2234@2|Bacteria,2IDP0@201174|Actinobacteria,4DZ4R@85010|Pseudonocardiales	201174|Actinobacteria	E	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
TLS3_k127_7419791_0	1120948.KB903244_gene3009	9.57e-160	513.0	COG0477@1|root,COG2814@2|Bacteria,2H8UD@201174|Actinobacteria,4DXSZ@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
TLS3_k127_7423797_3	1120948.KB903217_gene922	1.153e-118	383.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4DZBG@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
TLS3_k127_7423797_2	1120948.KB903217_gene921	2.146e-212	685.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4DY16@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknA	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0040007,GO:0042304,GO:0043085,GO:0043086,GO:0043170,GO:0043388,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051055,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
TLS3_k127_7423797_0	1120948.KB903217_gene920	3.074e-228	742.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4DYBM@85010|Pseudonocardiales	201174|Actinobacteria	M	Cell division protein FtsI penicillin-binding protein 2	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
TLS3_k127_7423797_1	1120948.KB903217_gene919	8.175e-224	714.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4DZX9@85010|Pseudonocardiales	201174|Actinobacteria	D	Belongs to the SEDS family	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
TLS3_k127_7423797_4	1120948.KB903217_gene918	8.559e-38	148.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4DX84@85010|Pseudonocardiales	201174|Actinobacteria	T	PFAM Protein phosphatase	pstP	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
TLS3_k127_7448629_0	1429046.RR21198_4365	7.525e-201	636.0	COG1249@1|root,COG1249@2|Bacteria,2GMP7@201174|Actinobacteria,4FVA3@85025|Nocardiaceae	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
TLS3_k127_7448629_1	1120948.KB903243_gene2331	7.386e-91	302.0	COG3703@1|root,COG3703@2|Bacteria,2GJM9@201174|Actinobacteria,4E2N8@85010|Pseudonocardiales	201174|Actinobacteria	P	AIG2-like family	-	-	-	-	-	-	-	-	-	-	-	-	AIG2_2
TLS3_k127_7448629_2	356851.JOAN01000011_gene5448	0.0004237	48.0	COG2183@1|root,COG2183@2|Bacteria,2GKCI@201174|Actinobacteria,4D9CE@85008|Micromonosporales	201174|Actinobacteria	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
TLS3_k127_7466963_3	405948.SACE_5253	2.552e-81	293.0	COG0457@1|root,COG0457@2|Bacteria,2GKX5@201174|Actinobacteria,4E0J1@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the DEAD box helicase family	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
TLS3_k127_7466963_1	1120948.KB903222_gene615	3.24e-115	391.0	COG0647@1|root,COG0647@2|Bacteria,2GK7V@201174|Actinobacteria,4DYNW@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM Haloacid Dehalogenase Superfamily Class (subfamily) IIA	yutF	GO:0000121,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030145,GO:0042578,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0046475,GO:0046486,GO:0046503,GO:0046872,GO:0046914,GO:0046983,GO:0050897,GO:0071704,GO:1901575	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
TLS3_k127_7466963_2	1120948.KB903222_gene613	5.678e-114	378.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,4DY8F@85010|Pseudonocardiales	201174|Actinobacteria	J	TIGRFAM hemolysin TlyA family protein	tlyA	GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
TLS3_k127_7466963_0	1120948.KB903222_gene612	9.828e-153	492.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4DYJH@85010|Pseudonocardiales	201174|Actinobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
TLS3_k127_7466963_4	1120948.KB903222_gene611	9.858e-71	243.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4DZRF@85010|Pseudonocardiales	201174|Actinobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
TLS3_k127_7474973_1	446462.Amir_5408	1.412e-89	306.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,4E11Q@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Lactonase,Pkinase
TLS3_k127_7474973_0	1120948.KB903221_gene417	8.741e-122	400.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,2GKEU@201174|Actinobacteria,4E2GT@85010|Pseudonocardiales	201174|Actinobacteria	V	Forkhead associated domain	-	-	-	ko:K01990,ko:K21397	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA
TLS3_k127_7477247_0	1223543.GP2_013_00860	3.421e-273	852.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4GAZX@85026|Gordoniaceae	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
TLS3_k127_7477247_3	1120948.KB903245_gene3503	2.277e-93	318.0	COG0406@1|root,COG1051@1|root,COG0406@2|Bacteria,COG1051@2|Bacteria,2I2N2@201174|Actinobacteria,4DZW1@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
TLS3_k127_7477247_7	1121087.AUCK01000010_gene3118	1.187e-28	126.0	COG2273@1|root,COG2273@2|Bacteria,1V29X@1239|Firmicutes,4HU56@91061|Bacilli,1ZF0E@1386|Bacillus	91061|Bacilli	G	Glycosyl hydrolases family 16	exoK	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_16
TLS3_k127_7477247_2	35754.JNYJ01000043_gene4605	6.32e-99	337.0	COG0642@1|root,COG2205@2|Bacteria,2I44X@201174|Actinobacteria,4DHGS@85008|Micromonosporales	201174|Actinobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA
TLS3_k127_7477247_1	35754.JNYJ01000043_gene4598	3.665e-171	563.0	COG1215@1|root,COG1215@2|Bacteria,2GJCE@201174|Actinobacteria,4DC5P@85008|Micromonosporales	201174|Actinobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
TLS3_k127_7477247_4	35754.JNYJ01000043_gene4597	1.126e-67	248.0	COG1413@1|root,COG1413@2|Bacteria,2INKI@201174|Actinobacteria,4DHQ2@85008|Micromonosporales	201174|Actinobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
TLS3_k127_7477247_5	196162.Noca_1748	1.216e-44	166.0	COG0745@1|root,COG0745@2|Bacteria,2IQWH@201174|Actinobacteria,4DUUQ@85009|Propionibacteriales	201174|Actinobacteria	T	cheY-homologous receiver domain	ompR	-	-	-	-	-	-	-	-	-	-	-	Response_reg
TLS3_k127_7477247_6	1120948.KB903245_gene3510	2.305e-41	153.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4DXND@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2987c	Aconitase_C
TLS3_k127_7478113_0	1120948.KB903240_gene3774	2.142e-143	461.0	COG0671@1|root,COG1597@1|root,COG0671@2|Bacteria,COG1597@2|Bacteria,2GM2U@201174|Actinobacteria,4DXZQ@85010|Pseudonocardiales	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain	bmrU	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DAGK_cat,PAP2
TLS3_k127_7478113_2	211114.JOEF01000006_gene2460	6.022e-119	413.0	COG0671@1|root,COG1597@1|root,COG0671@2|Bacteria,COG1597@2|Bacteria,2GM2U@201174|Actinobacteria,4DXZQ@85010|Pseudonocardiales	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain	bmrU	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DAGK_cat,PAP2
TLS3_k127_7478113_1	1120948.KB903240_gene3775	2.205e-121	396.0	COG0638@1|root,COG0638@2|Bacteria,2GKZ1@201174|Actinobacteria,4E0RK@85010|Pseudonocardiales	201174|Actinobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcA	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0030312,GO:0032991,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
TLS3_k127_7478113_3	1120948.KB903240_gene3776	2.583e-115	377.0	COG0638@1|root,COG0638@2|Bacteria,2GJ60@201174|Actinobacteria,4DY60@85010|Pseudonocardiales	201174|Actinobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcB	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
TLS3_k127_7480531_8	1120948.KB903225_gene5553	5.707e-45	181.0	COG5297@1|root,COG5297@2|Bacteria,2HDPZ@201174|Actinobacteria,4E329@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 12	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_12,RicinB_lectin_2,Ricin_B_lectin
TLS3_k127_7480531_0	1120948.KB903225_gene5552	0.0	1022.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4E1U7@85010|Pseudonocardiales	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	2.2.1.6,2.5.1.66	ko:K01652,ko:K12673	ko00290,ko00331,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00331,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570,M00674	R00006,R00014,R00226,R03050,R04672,R04673,R05465,R08648	RC00027,RC00106,RC00215,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TLS3_k127_7480531_6	1120948.KB903240_gene3738	1.881e-61	220.0	COG3707@1|root,COG3707@2|Bacteria,2IISX@201174|Actinobacteria,4EERV@85010|Pseudonocardiales	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
TLS3_k127_7480531_10	345341.KUTG_08061	9.681e-20	92.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4DX69@85010|Pseudonocardiales	201174|Actinobacteria	Q	cytochrome P450	-	-	1.14.19.8	ko:K17476	ko01130,map01130	M00819	R10162	RC03132	ko00000,ko00001,ko00002,ko00199,ko01000	-	-	-	p450
TLS3_k127_7480531_4	1120948.KB903217_gene962	4.647e-122	398.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4E0HI@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.304,1.1.1.76	ko:K00059,ko:K18009	ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R03707,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R09078,R10116,R10120,R10505,R11671	RC00029,RC00117,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_7480531_11	1120948.KB903218_gene1831	6.698e-18	98.0	2E7QZ@1|root,32C42@2|Bacteria,2ITFA@201174|Actinobacteria,4ED1V@85010|Pseudonocardiales	201174|Actinobacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
TLS3_k127_7480531_5	882083.SacmaDRAFT_4870	1.761e-100	347.0	COG4264@1|root,COG4264@2|Bacteria,2GKU8@201174|Actinobacteria,4E33D@85010|Pseudonocardiales	201174|Actinobacteria	Q	IucA / IucC family	-	-	-	-	-	-	-	-	-	-	-	-	FhuF,IucA_IucC
TLS3_k127_7480531_3	1120948.KB903218_gene1806	6.467e-151	487.0	COG1752@1|root,COG1752@2|Bacteria,2IA6V@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
TLS3_k127_7480531_12	367299.JOEE01000005_gene3606	9.981e-15	78.0	COG3871@1|root,COG3871@2|Bacteria,2IQDD@201174|Actinobacteria,4FHGQ@85021|Intrasporangiaceae	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
TLS3_k127_7480531_9	2074.JNYD01000014_gene7079	5.552e-27	115.0	COG0789@1|root,COG0789@2|Bacteria,2IKRM@201174|Actinobacteria,4E4DY@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM MerR family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
TLS3_k127_7480531_7	1120948.KB903248_gene4378	7.082e-59	207.0	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria,4E3CV@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
TLS3_k127_7480531_2	1120950.KB892776_gene796	2.764e-165	531.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4DP99@85009|Propionibacteriales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
TLS3_k127_7480531_1	1120948.KB903243_gene2596	9.501e-193	602.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4DZE6@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
TLS3_k127_7490698_10	1089544.KB912942_gene575	1.509e-16	80.0	COG0393@1|root,COG0393@2|Bacteria,2IHTU@201174|Actinobacteria,4E69Y@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
TLS3_k127_7490698_6	1120948.KB903217_gene1348	3.076e-62	240.0	COG1309@1|root,COG1309@2|Bacteria,2GIUW@201174|Actinobacteria,4E1BY@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_7490698_0	1120948.KB903217_gene1349	6.444e-297	915.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4E0IR@85010|Pseudonocardiales	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	accD1	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
TLS3_k127_7490698_1	1120948.KB903217_gene1350	5.165e-284	912.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4DZPP@85010|Pseudonocardiales	201174|Actinobacteria	I	Acetyl propionyl-CoA carboxylase, alpha subunit	accA1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2501c	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
TLS3_k127_7490698_3	1120948.KB903217_gene1351	7.946e-199	648.0	COG1960@1|root,COG1960@2|Bacteria,2GMEM@201174|Actinobacteria,4DXNR@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE19	GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681	1.3.8.1,1.3.99.12	ko:K00248,ko:K11410	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
TLS3_k127_7490698_9	1120948.KB903217_gene1353	8.802e-24	116.0	2EHE1@1|root,33B5X@2|Bacteria	2|Bacteria	S	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	DUF2834
TLS3_k127_7490698_5	1120948.KB903217_gene1354	5.107e-104	347.0	28PB4@1|root,2ZC42@2|Bacteria,2GP5R@201174|Actinobacteria,4E1BG@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7490698_7	1120948.KB903217_gene1355	3.486e-54	198.0	COG0789@1|root,COG0789@2|Bacteria,2I9B3@201174|Actinobacteria,4E4RJ@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
TLS3_k127_7490698_4	547163.BN979_04427	6.039e-146	473.0	COG2141@1|root,COG2141@2|Bacteria,2GJTP@201174|Actinobacteria,2385I@1762|Mycobacteriaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_7490698_8	1120948.KB903217_gene1357	5.204e-38	164.0	COG0346@1|root,COG0346@2|Bacteria,2IHZH@201174|Actinobacteria,4E4CC@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	gloA	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_7490698_2	1120948.KB903217_gene1358	1.307e-219	698.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DXTD@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1,Sugar_tr
TLS3_k127_7490698_11	35754.JNYJ01000020_gene234	2.118e-13	73.0	COG3237@1|root,COG3237@2|Bacteria,2GQQ4@201174|Actinobacteria,4DFT3@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
TLS3_k127_7496158_2	1120948.KB903219_gene788	8.909e-117	380.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4E2CC@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
TLS3_k127_7496158_1	1120948.KB903219_gene787	1.895e-182	574.0	COG2421@1|root,COG2421@2|Bacteria,2HQSF@201174|Actinobacteria,4E0X2@85010|Pseudonocardiales	201174|Actinobacteria	C	Acetamidase/Formamidase family	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
TLS3_k127_7496158_7	1120948.KB903219_gene785	2.04e-52	210.0	2BR83@1|root,32K6E@2|Bacteria,2IN4J@201174|Actinobacteria,4E559@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7496158_0	1120948.KB903219_gene784	7.364e-227	718.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4DXHY@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
TLS3_k127_7496158_4	1120948.KB903219_gene783	1.421e-74	260.0	COG4758@1|root,COG4758@2|Bacteria,2IB37@201174|Actinobacteria,4EEWF@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707
TLS3_k127_7496158_3	44060.JODL01000007_gene1270	5.681e-77	268.0	COG1470@1|root,COG1470@2|Bacteria,2GP8D@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
TLS3_k127_7496158_11	1120948.KB903219_gene781	2.438e-14	74.0	COG3237@1|root,COG3237@2|Bacteria,2GQQ4@201174|Actinobacteria,4E7NI@85010|Pseudonocardiales	201174|Actinobacteria	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
TLS3_k127_7496158_10	105420.BBPO01000002_gene7506	1.223e-17	96.0	COG0346@1|root,COG0346@2|Bacteria,2IKNC@201174|Actinobacteria,2NJGI@228398|Streptacidiphilus	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
TLS3_k127_7496158_8	644283.Micau_3323	7.551e-41	160.0	COG1309@1|root,COG1309@2|Bacteria,2IQAR@201174|Actinobacteria,4DF41@85008|Micromonosporales	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
TLS3_k127_7496158_5	1136417.AZWE01000006_gene4271	6.427e-59	210.0	28NRE@1|root,30A1Y@2|Bacteria,2IM0Z@201174|Actinobacteria,4DE4G@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7496158_6	1457250.BBMO01000001_gene1688	1.307e-58	229.0	COG0702@1|root,arCOG03015@2157|Archaea,2Y1X3@28890|Euryarchaeota,23YEJ@183963|Halobacteria	183963|Halobacteria	M	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
TLS3_k127_7497495_0	1120948.KB903246_gene3273	2.998e-241	760.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4E04K@85010|Pseudonocardiales	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
TLS3_k127_7497495_1	1120948.KB903246_gene3274	3.162e-102	347.0	COG1520@1|root,COG1520@2|Bacteria,2GJM4@201174|Actinobacteria,4EFAN@85010|Pseudonocardiales	201174|Actinobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TLS3_k127_7497495_2	103733.JNYO01000012_gene2660	2.995e-45	180.0	COG2267@1|root,COG2267@2|Bacteria,2GKPK@201174|Actinobacteria,4DYYA@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
TLS3_k127_7502728_2	1120948.KB903244_gene3000	3.103e-29	119.0	2EFU9@1|root,339KE@2|Bacteria,2GQJW@201174|Actinobacteria,4E6KE@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3046)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3046
TLS3_k127_7502728_0	1206744.BAGL01000033_gene167	1.262e-156	511.0	COG1807@1|root,COG1807@2|Bacteria,2GK3Q@201174|Actinobacteria,4G4PQ@85025|Nocardiaceae	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
TLS3_k127_7502728_1	1246995.AFR_21930	7.182e-40	165.0	COG4585@1|root,COG4585@2|Bacteria,2GNBG@201174|Actinobacteria,4DBDK@85008|Micromonosporales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
TLS3_k127_7516027_0	675635.Psed_6113	7.102e-232	719.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4DXTY@85010|Pseudonocardiales	201174|Actinobacteria	O	with chaperone activity, ATP-binding subunit	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
TLS3_k127_7516027_1	1209984.BN978_03232	1.716e-115	387.0	COG0739@1|root,COG0739@2|Bacteria,2I9IY@201174|Actinobacteria,234ZC@1762|Mycobacteriaceae	201174|Actinobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_7516027_4	1123251.ATWM01000007_gene2345	2.095e-12	76.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4FFBU@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TLS3_k127_7516027_3	1120948.KB903229_gene5384	8.34e-43	161.0	2C4MW@1|root,32RKK@2|Bacteria,2IQ6A@201174|Actinobacteria,4E4CX@85010|Pseudonocardiales	201174|Actinobacteria	S	Lsr2	lsr2	GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009628,GO:0009636,GO:0009889,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031668,GO:0033554,GO:0034641,GO:0040007,GO:0042221,GO:0042262,GO:0042493,GO:0042542,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071496,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	Lsr2
TLS3_k127_7516027_2	1120948.KB903229_gene5383	9.473e-67	229.0	COG1335@1|root,COG1335@2|Bacteria,2GPE0@201174|Actinobacteria,4E5AM@85010|Pseudonocardiales	201174|Actinobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
TLS3_k127_7529250_0	1120948.KB903217_gene1655	0.0	1721.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4DYKC@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
TLS3_k127_7535259_5	313589.JNB_18968	9.746e-14	84.0	COG1652@1|root,COG1652@2|Bacteria,2GQMU@201174|Actinobacteria,4FH7Q@85021|Intrasporangiaceae	201174|Actinobacteria	S	PFAM Peptidoglycan-binding lysin domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
TLS3_k127_7535259_3	1385519.N801_02015	4.373e-52	190.0	2E4C6@1|root,32Z7Q@2|Bacteria,2GRH1@201174|Actinobacteria,4FGSQ@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7535259_4	1385518.N798_16940	2.039e-28	115.0	COG3311@1|root,COG3311@2|Bacteria,2GR98@201174|Actinobacteria,4FHBW@85021|Intrasporangiaceae	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
TLS3_k127_7535259_2	367299.JOEE01000003_gene2930	3.324e-52	199.0	COG1261@1|root,COG1261@2|Bacteria,2GR8T@201174|Actinobacteria,4FGD8@85021|Intrasporangiaceae	201174|Actinobacteria	NO	SAF	-	-	-	-	-	-	-	-	-	-	-	-	ChapFlgA,SAF
TLS3_k127_7535259_1	710696.Intca_2495	8.331e-109	378.0	COG0455@1|root,COG0455@2|Bacteria,2IARP@201174|Actinobacteria,4FFKI@85021|Intrasporangiaceae	201174|Actinobacteria	D	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
TLS3_k127_7535259_0	1385520.N802_18330	8.252e-109	378.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4FEF5@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	tgs3	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
TLS3_k127_7614113_0	994479.GL877884_gene7681	1.988e-111	374.0	COG0523@1|root,COG0523@2|Bacteria,2GKDR@201174|Actinobacteria,4DYCM@85010|Pseudonocardiales	201174|Actinobacteria	S	Cobalamin synthesis protein cobW C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
TLS3_k127_7624702_1	136273.GY22_11475	5.382e-97	321.0	COG0028@1|root,COG0028@2|Bacteria,2GKGX@201174|Actinobacteria,1W8A4@1268|Micrococcaceae	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TLS3_k127_7624702_3	2074.JNYD01000047_gene7424	2.825e-73	251.0	COG0778@1|root,COG0778@2|Bacteria,2IEFM@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase family	-	-	1.3.3.13	ko:K21375	-	-	-	-	ko00000,ko01000	-	-	-	Nitroreductase
TLS3_k127_7624702_8	2074.JNYD01000047_gene7423	3.688e-31	124.0	2F798@1|root,33ZQF@2|Bacteria,2H703@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7624702_7	2074.JNYD01000003_gene3918	4.209e-36	141.0	COG2329@1|root,COG2329@2|Bacteria,2H1KI@201174|Actinobacteria	201174|Actinobacteria	S	antibiotic biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ABM
TLS3_k127_7624702_4	590998.Celf_3572	2.333e-66	233.0	COG4430@1|root,COG4430@2|Bacteria,2II0D@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
TLS3_k127_7624702_6	882083.SacmaDRAFT_4483	5.595e-41	168.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria,4E6WF@85010|Pseudonocardiales	201174|Actinobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
TLS3_k127_7624702_2	1120948.KB903229_gene5058	3.867e-90	313.0	COG1881@1|root,COG1881@2|Bacteria,2GMIG@201174|Actinobacteria,4DYXA@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM Raf kinase inhibitor-like protein, YbhB YbcL family	ybhB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
TLS3_k127_7624702_5	1122247.C731_2012	1.374e-54	201.0	2AW9K@1|root,31N50@2|Bacteria,2IP39@201174|Actinobacteria,23AHF@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7624702_0	408672.NBCG_04420	1.3e-197	618.0	COG2515@1|root,COG2515@2|Bacteria,2GIV5@201174|Actinobacteria,4DPG5@85009|Propionibacteriales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	acdS	-	3.5.99.7,4.4.1.15	ko:K01505,ko:K05396	ko00270,map00270	-	R00997,R01874	RC00382,RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
TLS3_k127_7624702_9	1306174.JODP01000006_gene2850	3.224e-27	113.0	COG1802@1|root,COG1802@2|Bacteria,2I8SM@201174|Actinobacteria	201174|Actinobacteria	K	gntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
TLS3_k127_7653566_1	1120948.KB903245_gene3481	8.059e-147	479.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4DX3U@85010|Pseudonocardiales	201174|Actinobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon
TLS3_k127_7653566_2	1120948.KB903245_gene3482	4.721e-26	124.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4E758@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
TLS3_k127_7653566_3	1289387.AUKW01000002_gene195	1.503e-15	83.0	2E6IT@1|root,3315W@2|Bacteria,2GR2R@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF397
TLS3_k127_7653566_0	675635.Psed_3090	2.463e-165	523.0	COG3039@1|root,COG3039@2|Bacteria,2GJQM@201174|Actinobacteria,4DZWS@85010|Pseudonocardiales	201174|Actinobacteria	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_3
TLS3_k127_7653566_4	1120948.KB903223_gene269	1.873e-08	66.0	COG3871@1|root,COG3871@2|Bacteria,2I2S9@201174|Actinobacteria,4E3EK@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
TLS3_k127_7679041_1	1120948.KB903248_gene4308	2.478e-195	615.0	COG0003@1|root,COG0003@2|Bacteria,2GISZ@201174|Actinobacteria,4DYJQ@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM Anion-transporting ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
TLS3_k127_7679041_3	1120948.KB903248_gene4309	8.372e-67	232.0	COG2867@1|root,COG2867@2|Bacteria,2IFH4@201174|Actinobacteria,4E3HW@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
TLS3_k127_7679041_4	2074.JNYD01000003_gene3993	1.509e-44	166.0	COG2867@1|root,COG2867@2|Bacteria,2IIBS@201174|Actinobacteria,4E607@85010|Pseudonocardiales	201174|Actinobacteria	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7679041_0	1120948.KB903248_gene4312	1.647e-296	931.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DY3I@85010|Pseudonocardiales	201174|Actinobacteria	I	AMP-forming long-chain acyl-CoA synthetase	fadD15	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
TLS3_k127_7679041_2	31964.CMS0578	5.645e-127	413.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,4FKT9@85023|Microbacteriaceae	201174|Actinobacteria	L	insertion element IS1121 transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,LZ_Tnp_IS481,rve,rve_3
TLS3_k127_7679041_6	1120948.KB903217_gene1181	1.032e-05	50.0	COG1215@1|root,COG1215@2|Bacteria,2I2NS@201174|Actinobacteria,4E3D6@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
TLS3_k127_7722287_1	1123024.AUII01000038_gene4082	2.179e-180	575.0	COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4E235@85010|Pseudonocardiales	201174|Actinobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
TLS3_k127_7722287_10	1283299.AUKG01000002_gene4742	1.224e-23	116.0	COG0454@1|root,COG0456@2|Bacteria,2GNNG@201174|Actinobacteria,4CQUQ@84995|Rubrobacteria	84995|Rubrobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_7722287_9	438753.AZC_4699	1.467e-29	124.0	COG1309@1|root,COG1309@2|Bacteria,1N7CN@1224|Proteobacteria	1224|Proteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_7722287_0	2074.JNYD01000015_gene4537	2.346e-234	736.0	COG0654@1|root,COG0654@2|Bacteria,2GN2W@201174|Actinobacteria,4DXWE@85010|Pseudonocardiales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
TLS3_k127_7722287_7	1306174.JODP01000008_gene2677	4.289e-50	191.0	COG3629@1|root,COG3629@2|Bacteria,2IC17@201174|Actinobacteria	201174|Actinobacteria	T	DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
TLS3_k127_7722287_13	1120948.KB903227_gene4897	0.0008741	42.0	COG3546@1|root,COG3546@2|Bacteria,2GKIM@201174|Actinobacteria,4E01C@85010|Pseudonocardiales	201174|Actinobacteria	P	Catalase	-	-	-	ko:K07217	-	-	-	-	ko00000	-	-	-	Mn_catalase
TLS3_k127_7722287_11	1120948.KB903218_gene1832	1.086e-13	81.0	2BDAW@1|root,327FH@2|Bacteria,2HD47@201174|Actinobacteria,4EDCX@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7722287_2	1001240.GY21_12035	6.49e-121	402.0	COG1680@1|root,COG1680@2|Bacteria,2H2SY@201174|Actinobacteria,4FSC1@85023|Microbacteriaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
TLS3_k127_7722287_5	1123024.AUII01000002_gene1006	3.631e-66	235.0	COG1670@1|root,COG1670@2|Bacteria,2IQW2@201174|Actinobacteria,4E2W3@85010|Pseudonocardiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006104,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TLS3_k127_7722287_3	929712.KI912613_gene2307	2.39e-86	293.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4CRZR@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
TLS3_k127_7722287_4	1120948.KB903227_gene4887	3.85e-73	254.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4E3X3@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
TLS3_k127_7722287_6	1120948.KB903243_gene2477	2.542e-55	209.0	COG1302@1|root,COG1302@2|Bacteria,2IR3R@201174|Actinobacteria	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
TLS3_k127_7722287_8	1120948.KB903229_gene5312	6.705e-34	140.0	COG1309@1|root,COG1309@2|Bacteria,2I0IN@201174|Actinobacteria,4E5GE@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_7762839_1	208444.JNYY01000025_gene5964	5.188e-49	194.0	COG1672@1|root,COG2197@1|root,COG1672@2|Bacteria,COG2197@2|Bacteria,2I3QJ@201174|Actinobacteria,4EF66@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_7762839_0	1089545.KB913037_gene529	2.249e-152	505.0	COG0443@1|root,COG0443@2|Bacteria,2GNTE@201174|Actinobacteria,4E043@85010|Pseudonocardiales	201174|Actinobacteria	O	Hsp70 protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
TLS3_k127_7764775_4	1306174.JODP01000008_gene2686	7.995e-89	297.0	COG2175@1|root,COG2175@2|Bacteria,2GNUC@201174|Actinobacteria	201174|Actinobacteria	Q	taurine catabolism dioxygenase	-	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
TLS3_k127_7764775_3	1370125.AUWT01000051_gene794	1.903e-94	325.0	COG4122@1|root,COG4122@2|Bacteria,2GP7A@201174|Actinobacteria,2387S@1762|Mycobacteriaceae	201174|Actinobacteria	S	O-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
TLS3_k127_7764775_2	1120948.KB903244_gene2985	3.572e-179	569.0	COG0337@1|root,COG0337@2|Bacteria,2H9BI@201174|Actinobacteria,4E38S@85010|Pseudonocardiales	201174|Actinobacteria	E	3-dehydroquinate synthase	-	-	4.2.3.152,4.2.3.154,4.2.3.4	ko:K01735,ko:K19969,ko:K21342	ko00400,ko00525,ko01100,ko01110,ko01130,ko01230,map00400,map00525,map01100,map01110,map01130,map01230	M00022,M00814,M00815	R03083,R10937	RC00847,RC03308	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
TLS3_k127_7764775_5	1370125.AUWT01000051_gene796	1.429e-68	241.0	COG0637@1|root,COG0637@2|Bacteria,2HEXC@201174|Actinobacteria,238NK@1762|Mycobacteriaceae	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
TLS3_k127_7764775_0	2074.JNYD01000003_gene3644	6.183e-264	858.0	COG0726@1|root,COG1215@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,2GJCE@201174|Actinobacteria,4DZV9@85010|Pseudonocardiales	201174|Actinobacteria	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2,Polysacc_deac_1
TLS3_k127_7764775_6	1146883.BLASA_4176	3.097e-43	163.0	COG1670@1|root,COG1670@2|Bacteria,2GMDB@201174|Actinobacteria,4ETAW@85013|Frankiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
TLS3_k127_7764775_1	566461.SSFG_01440	3.795e-233	725.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	yfbQ	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2,HTH_3
TLS3_k127_7766551_1	1120948.KB903218_gene2000	2.556e-50	186.0	COG0155@1|root,COG0155@2|Bacteria,2GNUG@201174|Actinobacteria,4E275@85010|Pseudonocardiales	201174|Actinobacteria	P	Sulfite reductase, beta subunit (Hemoprotein)	cobG	-	1.14.13.83	ko:K02229	ko00860,ko01100,map00860,map01100	-	R05217	RC01979	ko00000,ko00001,ko01000	-	-	-	NIR_SIR_ferr
TLS3_k127_7766551_0	58344.JOEL01000060_gene4276	3.174e-303	944.0	COG1429@1|root,COG1429@2|Bacteria,2GK0U@201174|Actinobacteria	201174|Actinobacteria	H	cobaltochelatase CobN subunit	cobN	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	iNJ661.Rv2062c	CobN-Mg_chel
TLS3_k127_7790501_5	1120948.KB903217_gene978	2.386e-57	203.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4DXBM@85010|Pseudonocardiales	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
TLS3_k127_7790501_4	1120948.KB903217_gene979	3.956e-71	248.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4E3Q7@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the UPF0232 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
TLS3_k127_7790501_1	1120948.KB903217_gene980	1.147e-176	563.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4DYPY@85010|Pseudonocardiales	201174|Actinobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
TLS3_k127_7790501_2	1120948.KB903217_gene981	8.754e-170	539.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,4DYVC@85010|Pseudonocardiales	201174|Actinobacteria	G	6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
TLS3_k127_7790501_0	1120948.KB903217_gene982	3.735e-213	676.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4E16V@85010|Pseudonocardiales	201174|Actinobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
TLS3_k127_7790501_3	1120948.KB903217_gene983	1.312e-146	465.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4E04J@85010|Pseudonocardiales	201174|Actinobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
TLS3_k127_7791756_6	1120948.KB903240_gene3923	2.496e-05	49.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4E2BN@85010|Pseudonocardiales	201174|Actinobacteria	H	Riboflavin synthase	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
TLS3_k127_7791756_3	1120948.KB903240_gene3924	3.158e-114	379.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4DY90@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
TLS3_k127_7791756_1	1120948.KB903240_gene3925	2.76e-235	743.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2GM21@201174|Actinobacteria,4DZAD@85010|Pseudonocardiales	201174|Actinobacteria	JK	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	fmu	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
TLS3_k127_7791756_2	1120948.KB903240_gene3926	6.524e-138	455.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4E0PB@85010|Pseudonocardiales	201174|Actinobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
TLS3_k127_7791756_4	1120948.KB903240_gene3927	2.3e-84	288.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4DZRR@85010|Pseudonocardiales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
TLS3_k127_7791756_5	543632.JOJL01000073_gene4866	3.377e-75	283.0	COG1576@1|root,COG1576@2|Bacteria,2IAXN@201174|Actinobacteria,4DDAA@85008|Micromonosporales	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
TLS3_k127_7791756_0	1120948.KB903240_gene3928	1.332e-306	955.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4E00W@85010|Pseudonocardiales	201174|Actinobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
TLS3_k127_7805149_3	1120948.KB903244_gene2851	1.166e-131	459.0	COG1232@1|root,COG1232@2|Bacteria,2GMMA@201174|Actinobacteria,4E014@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
TLS3_k127_7805149_0	1120948.KB903244_gene2852	2.103e-170	557.0	COG0407@1|root,COG0407@2|Bacteria,2GMY6@201174|Actinobacteria,4DYZ3@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
TLS3_k127_7805149_7	1120948.KB903244_gene2853	3.495e-83	288.0	2AIF4@1|root,318WM@2|Bacteria,2GK8R@201174|Actinobacteria,4E2AK@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3000)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3000
TLS3_k127_7805149_4	1120948.KB903244_gene2854	1.387e-121	395.0	COG2197@1|root,COG2197@2|Bacteria,2GIXT@201174|Actinobacteria,4DXKI@85010|Pseudonocardiales	201174|Actinobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_7805149_1	103733.JNYO01000027_gene2411	2.892e-159	518.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4E0Q2@85010|Pseudonocardiales	201174|Actinobacteria	J	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
TLS3_k127_7805149_2	1120948.KB903244_gene2856	2.166e-147	476.0	COG0642@1|root,COG2205@2|Bacteria,2GJMV@201174|Actinobacteria,4DXSD@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	cutS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
TLS3_k127_7805149_5	1120948.KB903244_gene2860	3.256e-116	377.0	COG0745@1|root,COG0745@2|Bacteria,2GKYV@201174|Actinobacteria,4DXF4@85010|Pseudonocardiales	201174|Actinobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_7805149_6	1120948.KB903244_gene2861	1.576e-113	373.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4DXY8@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
TLS3_k127_7805149_8	645465.ACUR01000433_gene2078	1.257e-43	163.0	COG0388@1|root,COG0388@2|Bacteria,2GKRJ@201174|Actinobacteria	201174|Actinobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
TLS3_k127_7810317_2	1120948.KB903244_gene2919	3.479e-112	366.0	COG3752@1|root,COG3752@2|Bacteria,2GNX1@201174|Actinobacteria,4E05A@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
TLS3_k127_7810317_7	1120948.KB903244_gene2917	9.047e-66	232.0	COG1225@1|root,COG1225@2|Bacteria,2IFB1@201174|Actinobacteria,4E31I@85010|Pseudonocardiales	201174|Actinobacteria	O	Redoxin	bcpB	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
TLS3_k127_7810317_4	1120948.KB903244_gene2916	3.556e-94	315.0	COG2267@1|root,COG2267@2|Bacteria,2I3AW@201174|Actinobacteria,4E38K@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4,Peptidase_S9
TLS3_k127_7810317_0	1120948.KB903244_gene2915	8.598e-201	637.0	COG2907@1|root,COG2907@2|Bacteria,2GJMW@201174|Actinobacteria,4E03X@85010|Pseudonocardiales	201174|Actinobacteria	S	amine oxidase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase,DUF1365
TLS3_k127_7810317_3	1120948.KB903244_gene2914	2.217e-94	330.0	COG3496@1|root,COG3496@2|Bacteria,2HBH1@201174|Actinobacteria,4DXS8@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
TLS3_k127_7810317_8	1120948.KB903244_gene2913	1.875e-65	240.0	COG0454@1|root,COG0456@2|Bacteria,2GJJZ@201174|Actinobacteria,4ECJX@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
TLS3_k127_7810317_6	1120948.KB903244_gene2912	2.856e-78	281.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria,4E2UK@85010|Pseudonocardiales	201174|Actinobacteria	L	HhH-GPD superfamily base excision DNA repair protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
TLS3_k127_7810317_9	1120948.KB903244_gene2900	2.143e-56	201.0	2EGIC@1|root,33AAH@2|Bacteria,2GTD1@201174|Actinobacteria,4EF14@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3099)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3099
TLS3_k127_7810317_1	1120948.KB903247_gene4423	8.26e-138	475.0	28I5U@1|root,2Z890@2|Bacteria,2GKEB@201174|Actinobacteria,4DZIG@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF1996)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1996
TLS3_k127_7810317_5	1120948.KB903243_gene2603	4.464e-81	289.0	2F02G@1|root,33T66@2|Bacteria,2IGPI@201174|Actinobacteria,4EASH@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7810317_10	1120948.KB903244_gene2899	3.807e-11	72.0	2CAFG@1|root,32RRB@2|Bacteria,2IQ98@201174|Actinobacteria,4EEBC@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3039)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3039
TLS3_k127_7810628_6	1120948.KB903217_gene1606	5.085e-14	72.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4DY36@85010|Pseudonocardiales	201174|Actinobacteria	F	IMP dehydrogenase GMP reductase	guaB3	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
TLS3_k127_7810628_1	1120948.KB903217_gene1618	5.397e-207	676.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria,4DXV4@85010|Pseudonocardiales	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_7810628_3	1120948.KB903217_gene1620	1.678e-64	237.0	29VND@1|root,33797@2|Bacteria,2HQHY@201174|Actinobacteria,4E9B9@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7810628_0	2074.JNYD01000011_gene167	0.0	1753.0	COG0369@1|root,COG2124@1|root,COG0369@2|Bacteria,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,4E0KA@85010|Pseudonocardiales	201174|Actinobacteria	Q	The reductase domain is required for electron transfer from NADP to cytochrome P450	cypD	-	1.14.14.1,1.6.2.4	ko:K00493,ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	-	R03629,R04121,R05259	RC00046,RC01311	ko00000,ko00001,ko00199,ko01000	-	-	-	FAD_binding_1,Flavodoxin_1,NAD_binding_1,p450
TLS3_k127_7810628_4	1120948.KB903217_gene1607	1.203e-16	82.0	COG1925@1|root,COG1925@2|Bacteria,2GQX6@201174|Actinobacteria,4E63H@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM Phosphotransferase System HPr (HPr) Family	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
TLS3_k127_7810628_2	935866.JAER01000005_gene85	1.093e-125	407.0	COG1690@1|root,COG1690@2|Bacteria,2GIUP@201174|Actinobacteria,4DPPZ@85009|Propionibacteriales	201174|Actinobacteria	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
TLS3_k127_7813033_4	43759.JNWK01000005_gene710	1.001e-58	209.0	COG4779@1|root,COG4779@2|Bacteria,2GJ7A@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
TLS3_k127_7813033_3	1896.JOAU01000012_gene706	1.827e-112	379.0	COG1120@1|root,COG1120@2|Bacteria,2GJ49@201174|Actinobacteria	201174|Actinobacteria	HP	abc transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
TLS3_k127_7813033_0	2074.JNYD01000008_gene1091	1.899e-220	689.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4DXVB@85010|Pseudonocardiales	201174|Actinobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	GO:0008150,GO:0040007	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
TLS3_k127_7813033_2	2074.JNYD01000003_gene3389	1.821e-128	432.0	COG2124@1|root,COG2124@2|Bacteria,2I9EA@201174|Actinobacteria,4E0TF@85010|Pseudonocardiales	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
TLS3_k127_7813033_5	1120948.KB903245_gene3644	7.849e-38	146.0	2BITH@1|root,32D19@2|Bacteria,2GTJR@201174|Actinobacteria,4E6IQ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7813033_1	1120948.KB903245_gene3643	2.485e-193	606.0	COG2185@1|root,COG2185@2|Bacteria,2I2N3@201174|Actinobacteria,4DZXB@85010|Pseudonocardiales	201174|Actinobacteria	I	Methylmalonyl-CoA mutase	meaA	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
TLS3_k127_7813276_3	1068980.ARVW01000001_gene2942	2.231e-95	331.0	COG1960@1|root,COG1960@2|Bacteria,2GKD9@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_N
TLS3_k127_7813276_5	1370121.AUWS01000006_gene5186	1.549e-79	274.0	COG3315@1|root,COG3315@2|Bacteria,2GP52@201174|Actinobacteria,232TD@1762|Mycobacteriaceae	201174|Actinobacteria	Q	O-Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
TLS3_k127_7813276_6	1120948.KB903229_gene5057	2.801e-68	244.0	COG1321@1|root,COG1321@2|Bacteria,2GK7P@201174|Actinobacteria,4DYN2@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	sirR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
TLS3_k127_7813276_11	414996.IL38_10645	9.368e-17	86.0	COG1918@1|root,COG1918@2|Bacteria,2GX6H@201174|Actinobacteria,409J4@622450|Actinopolysporales	201174|Actinobacteria	P	FeoA	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
TLS3_k127_7813276_2	1050202.KB913024_gene1688	5.308e-100	339.0	COG0370@1|root,COG0370@2|Bacteria,2GTV2@201174|Actinobacteria,40A3S@622450|Actinopolysporales	201174|Actinobacteria	P	Ferrous iron transport protein B	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
TLS3_k127_7813276_0	414996.IL38_10655	7.379e-210	661.0	COG0370@1|root,COG0370@2|Bacteria,2GTV2@201174|Actinobacteria,408YF@622450|Actinopolysporales	201174|Actinobacteria	P	Ferrous iron transport protein B C terminus	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
TLS3_k127_7813276_1	1120948.KB903240_gene4121	4.969e-100	333.0	COG5446@1|root,COG5446@2|Bacteria,2H6Y9@201174|Actinobacteria,4E3NJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Probable cobalt transporter subunit (CbtA)	-	-	-	-	-	-	-	-	-	-	-	-	CbtA
TLS3_k127_7813276_8	1429046.RR21198_5124	1.926e-38	150.0	COG0406@1|root,COG0406@2|Bacteria,2GMX5@201174|Actinobacteria,4FXPR@85025|Nocardiaceae	201174|Actinobacteria	G	Histidine phosphatase superfamily (branch 1)	gpmB	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
TLS3_k127_7813276_12	1079986.JH164838_gene4303	5.184e-14	76.0	COG0666@1|root,COG0666@2|Bacteria,2I9A2@201174|Actinobacteria	201174|Actinobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
TLS3_k127_7813276_4	1120948.KB903244_gene2911	8.821e-93	310.0	COG2243@1|root,COG2243@2|Bacteria,2GJFA@201174|Actinobacteria,4DZTS@85010|Pseudonocardiales	201174|Actinobacteria	H	precorrin-6A synthase (deacetylating)	cobF	-	2.1.1.152	ko:K02228	ko00860,ko01100,map00860,map01100	-	R05219	RC00003,RC00923,RC02890	ko00000,ko00001,ko01000	-	-	-	TP_methylase
TLS3_k127_7813276_7	298655.KI912266_gene3007	1.277e-59	212.0	COG4276@1|root,COG4276@2|Bacteria,2IIFF@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7813276_9	909613.UO65_4688	1.676e-30	127.0	COG2217@1|root,COG2217@2|Bacteria,2HNWX@201174|Actinobacteria,4DYTI@85010|Pseudonocardiales	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7815390_0	1120948.KB903229_gene5005	4.031e-165	526.0	COG0265@1|root,COG0265@2|Bacteria,2GJ92@201174|Actinobacteria,4DYKB@85010|Pseudonocardiales	201174|Actinobacteria	O	Trypsin-like serine protease with C-terminal PDZ domain	cvpA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
TLS3_k127_7815390_4	1120948.KB903229_gene5004	5.006e-80	286.0	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,4E0DD@85010|Pseudonocardiales	201174|Actinobacteria	L	pfam nudix	nudL	-	-	ko:K18568	ko00332,ko01130,map00332,map01130	-	R10747	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
TLS3_k127_7815390_5	1120948.KB903229_gene5003	5.441e-70	254.0	COG0526@1|root,COG0526@2|Bacteria,2IMNX@201174|Actinobacteria,4E4HZ@85010|Pseudonocardiales	201174|Actinobacteria	CO	Thiol-disulfide isomerase-like thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
TLS3_k127_7815390_1	1120948.KB903229_gene5002	4.365e-128	419.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4DXYV@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
TLS3_k127_7815390_8	1120948.KB903229_gene5001	3.774e-30	136.0	2ERSB@1|root,33JBI@2|Bacteria,2IQ49@201174|Actinobacteria,4E610@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7815390_2	1120948.KB903229_gene5000	6.558e-124	401.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4DYBS@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, crp family	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TLS3_k127_7815390_3	1120948.KB903229_gene4999	1.436e-116	397.0	COG0491@1|root,COG0491@2|Bacteria,2GKP9@201174|Actinobacteria,4DY1P@85010|Pseudonocardiales	201174|Actinobacteria	L	Metallo-beta-lactamase superfamily	pksB_1	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_7815390_6	1463825.JNXC01000026_gene3133	1.315e-49	186.0	COG0494@1|root,COG0494@2|Bacteria,2GN6D@201174|Actinobacteria,4DXPE@85010|Pseudonocardiales	201174|Actinobacteria	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
TLS3_k127_7815390_7	1174684.EBMC1_09609	7.724e-41	156.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,2TR1F@28211|Alphaproteobacteria,2K06J@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_7826235_11	1120792.JAFV01000001_gene2679	6.238e-08	55.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
TLS3_k127_7826235_1	266117.Rxyl_1558	5.864e-161	518.0	COG0665@1|root,COG0665@2|Bacteria,2I9WR@201174|Actinobacteria,4CSWG@84995|Rubrobacteria	84995|Rubrobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
TLS3_k127_7826235_2	1120948.KB903247_gene4446	1.594e-144	463.0	COG0583@1|root,COG0583@2|Bacteria,2GK13@201174|Actinobacteria,4E4XF@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
TLS3_k127_7826235_6	1120948.KB903247_gene4447	3.531e-74	265.0	COG1028@1|root,COG1028@2|Bacteria,2GKVM@201174|Actinobacteria,4E3Y7@85010|Pseudonocardiales	201174|Actinobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_7826235_10	1045009.AFXQ01000033_gene2610	1.841e-13	72.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,1W9Q8@1268|Micrococcaceae	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
TLS3_k127_7826235_9	1120948.KB903247_gene4449	5.562e-16	91.0	COG1141@1|root,COG1141@2|Bacteria,2GQHB@201174|Actinobacteria,4E7KX@85010|Pseudonocardiales	201174|Actinobacteria	C	Divergent 4Fe-4S mono-cluster	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15,Fer4_19
TLS3_k127_7826235_7	1120948.KB903247_gene4450	5.942e-45	179.0	COG1309@1|root,COG1309@2|Bacteria,2GIVD@201174|Actinobacteria,4E673@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_7826235_0	1120948.KB903247_gene4451	4.805e-233	739.0	COG2233@1|root,COG2233@2|Bacteria,2GMH6@201174|Actinobacteria,4DXV6@85010|Pseudonocardiales	201174|Actinobacteria	F	Permease family	rutG	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
TLS3_k127_7826235_3	2074.JNYD01000001_gene5909	1.441e-122	399.0	COG0604@1|root,COG0604@2|Bacteria,2GIWC@201174|Actinobacteria,4DYQQ@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
TLS3_k127_7826235_8	208444.JNYY01000009_gene3321	1.586e-32	132.0	2CGGQ@1|root,32S3Z@2|Bacteria,2IQ59@201174|Actinobacteria,4E5FI@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3140)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3140
TLS3_k127_7826235_4	675635.Psed_5174	3.396e-96	334.0	2AQY0@1|root,31G6M@2|Bacteria,2IEYJ@201174|Actinobacteria,4DY1Q@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7826235_5	37919.EP51_07175	6.266e-75	254.0	COG0174@1|root,COG0174@2|Bacteria,2IFHQ@201174|Actinobacteria,4FVI6@85025|Nocardiaceae	201174|Actinobacteria	E	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
TLS3_k127_7831177_1	1120948.KB903217_gene1007	5.422e-21	91.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria	201174|Actinobacteria	IQ	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
TLS3_k127_7831177_0	710421.Mycch_1471	5.124e-116	391.0	COG1541@1|root,COG1541@2|Bacteria,2HQVJ@201174|Actinobacteria,23A9G@1762|Mycobacteriaceae	201174|Actinobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
TLS3_k127_7831177_2	1120948.KB903217_gene1008	0.0001843	46.0	COG5658@1|root,COG5658@2|Bacteria	2|Bacteria	S	integral membrane protein	sdpI	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
TLS3_k127_7831503_1	1120948.KB903217_gene1640	7.295e-37	145.0	COG1605@1|root,COG1605@2|Bacteria,2IQ8K@201174|Actinobacteria,4E5DT@85010|Pseudonocardiales	201174|Actinobacteria	E	chorismate mutase	csm	GO:0003674,GO:0003824,GO:0004106,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016866,GO:0019438,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.99.5	ko:K04093	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
TLS3_k127_7831503_0	1120948.KB903217_gene1641	1.214e-118	388.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4DZQT@85010|Pseudonocardiales	201174|Actinobacteria	L	ATP-dependent DNA helicase	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
TLS3_k127_7832898_2	1120948.KB903217_gene1642	6.649e-126	407.0	COG3662@1|root,COG3662@2|Bacteria,2GJD2@201174|Actinobacteria,4DYDV@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
TLS3_k127_7832898_0	1120948.KB903243_gene2446	1.804e-216	675.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4DZ8P@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
TLS3_k127_7832898_5	1240349.ANGC01000017_gene4767	1.915e-78	282.0	COG4221@1|root,COG4221@2|Bacteria,2I2DY@201174|Actinobacteria,4FV05@85025|Nocardiaceae	201174|Actinobacteria	S	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
TLS3_k127_7832898_7	28444.JODQ01000002_gene4029	2.294e-31	130.0	COG5637@1|root,COG5637@2|Bacteria,2I3U7@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
TLS3_k127_7832898_6	675635.Psed_3135	3.528e-63	229.0	2AEJC@1|root,314EV@2|Bacteria,2GMTI@201174|Actinobacteria,4E3QP@85010|Pseudonocardiales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
TLS3_k127_7832898_3	1120948.KB903246_gene3228	2.631e-111	365.0	COG3917@1|root,COG3917@2|Bacteria,2I8XT@201174|Actinobacteria,4DZI0@85010|Pseudonocardiales	201174|Actinobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7832898_8	1120948.KB903218_gene1769	6.143e-21	103.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Beta_helix,Cellulose_synt,DUF3131,Glycos_transf_2
TLS3_k127_7832898_1	1123023.JIAI01000003_gene2568	2.188e-160	525.0	COG1432@1|root,COG1432@2|Bacteria,2HB6H@201174|Actinobacteria,4E62H@85010|Pseudonocardiales	201174|Actinobacteria	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
TLS3_k127_7832898_4	994479.GL877881_gene6634	2.571e-108	374.0	COG2309@1|root,COG2309@2|Bacteria,2I8N4@201174|Actinobacteria,4DZ0T@85010|Pseudonocardiales	201174|Actinobacteria	E	aminopeptidase activity	nicX	-	1.13.11.9	ko:K18028	ko00760,ko01120,map00760,map01120	M00622	R09125	RC02430	ko00000,ko00001,ko00002,ko01000	-	-	-	-
TLS3_k127_7852006_5	1194165.CAJF01000018_gene3577	7.115e-49	181.0	COG1266@1|root,COG1266@2|Bacteria,2I8AH@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi
TLS3_k127_7852006_4	526225.Gobs_3702	2.864e-50	183.0	COG1917@1|root,COG1917@2|Bacteria,2IIQY@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_7852006_2	2074.JNYD01000003_gene4094	2.091e-79	287.0	COG2311@1|root,COG2311@2|Bacteria,2I73Z@201174|Actinobacteria,4E3SK@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF418)	-	-	-	-	-	-	-	-	-	-	-	-	DUF418
TLS3_k127_7852006_6	1120948.KB903218_gene1979	3.565e-40	152.0	COG0640@1|root,COG0640@2|Bacteria,2GR57@201174|Actinobacteria,4E6WN@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5,MarR_2
TLS3_k127_7852006_1	1120948.KB903218_gene1978	5.626e-202	636.0	COG2021@1|root,COG2021@2|Bacteria,2GKNJ@201174|Actinobacteria,4E0SD@85010|Pseudonocardiales	201174|Actinobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
TLS3_k127_7852006_0	208444.JNYY01000004_gene2319	3.227e-238	743.0	COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4DZZ2@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Cys Met metabolism	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
TLS3_k127_7852006_3	1120948.KB903218_gene1933	4.609e-65	227.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4DZJ7@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	cyp	-	1.14.15.14	ko:K20497	-	-	-	-	ko00000,ko00199,ko01000	-	-	-	p450
TLS3_k127_7854848_1	1304275.C41B8_12424	2.013e-109	368.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the class I fructose-bisphosphate aldolase family	alf1	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
TLS3_k127_7854848_2	1380356.JNIK01000004_gene118	4.418e-69	242.0	COG0546@1|root,COG0546@2|Bacteria,2GIU8@201174|Actinobacteria,4EUIW@85013|Frankiales	201174|Actinobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
TLS3_k127_7854848_0	1120948.KB903240_gene3861	1.42e-285	881.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria,4DX8R@85010|Pseudonocardiales	201174|Actinobacteria	E	GMC oxidoreductase	betA	-	1.1.3.17,1.1.99.1	ko:K00108,ko:K17755	ko00260,ko01100,map00260,map01100	M00555	R01022,R01025,R08211,R08212	RC00080,RC00087,RC00651	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
TLS3_k127_787370_2	1123024.AUII01000010_gene668	5.294e-11	68.0	COG3284@1|root,COG3284@2|Bacteria,2H1NQ@201174|Actinobacteria,4E94H@85010|Pseudonocardiales	201174|Actinobacteria	KQ	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HTH_8
TLS3_k127_787370_0	1120948.KB903227_gene4899	1.167e-28	130.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009165,GO:0009166,GO:0009187,GO:0009190,GO:0009214,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0052621,GO:0055086,GO:0071111,GO:0071704,GO:0071944,GO:0090407,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,HWE_HK,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SpoIIE
TLS3_k127_787370_1	33876.JNXY01000004_gene1589	1.952e-24	103.0	COG2207@1|root,COG2207@2|Bacteria,2IBP1@201174|Actinobacteria,4DDGQ@85008|Micromonosporales	201174|Actinobacteria	K	AraC-binding-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
TLS3_k127_7880053_0	1120948.KB903243_gene2579	1.273e-78	275.0	COG1520@1|root,COG1520@2|Bacteria,2IIKH@201174|Actinobacteria,4E6ZD@85010|Pseudonocardiales	201174|Actinobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
TLS3_k127_7880053_2	1120948.KB903243_gene2576	8.379e-15	74.0	COG0589@1|root,COG0589@2|Bacteria,2IMMM@201174|Actinobacteria,4E4GY@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein	uspA3	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_7895054_6	1246448.ANAZ01000019_gene931	3.921e-10	63.0	COG1479@1|root,COG3472@1|root,COG1479@2|Bacteria,COG3472@2|Bacteria,2IF65@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
TLS3_k127_7895054_0	1120948.KB903217_gene1094	3.153e-111	378.0	2CA0C@1|root,30S8C@2|Bacteria,2IE01@201174|Actinobacteria,4EB38@85010|Pseudonocardiales	201174|Actinobacteria	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
TLS3_k127_7895054_2	1120948.KB903218_gene2167	4.031e-76	266.0	COG1573@1|root,COG1573@2|Bacteria	2|Bacteria	L	deaminated base DNA N-glycosylase activity	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
TLS3_k127_7895054_3	1120948.KB903217_gene1104	4.989e-63	219.0	COG3945@1|root,COG3945@2|Bacteria,2I92G@201174|Actinobacteria,4E60Z@85010|Pseudonocardiales	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
TLS3_k127_7895054_1	1380356.JNIK01000001_gene2254	1.042e-86	309.0	COG0515@1|root,COG0515@2|Bacteria,2I6W6@201174|Actinobacteria,4EXHA@85013|Frankiales	1380356.JNIK01000001_gene2254|-	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7895054_4	1120948.KB903218_gene2162	9.958e-33	132.0	2A1S7@1|root,30Q0V@2|Bacteria,2GTY5@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3293
TLS3_k127_7895054_7	1203605.HMPREF1531_00321	1.832e-07	57.0	2B2MF@1|root,31V6W@2|Bacteria,2GV3E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7895054_5	1449346.JQMO01000003_gene4017	9.474e-27	123.0	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,2GMBB@201174|Actinobacteria,2M644@2063|Kitasatospora	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7914864_2	1120948.KB903231_gene4710	1.654e-11	64.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4DX7X@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	pdtaS	GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2,PAS_4
TLS3_k127_7914864_1	1120948.KB903231_gene4709	1.354e-40	156.0	2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,4E5DV@85010|Pseudonocardiales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
TLS3_k127_7914864_0	1120948.KB903231_gene4708	1.676e-156	497.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4DX5P@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Diacylglycerol kinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
TLS3_k127_792034_2	1136417.AZWE01000013_gene2378	1.424e-77	265.0	COG1309@1|root,COG1309@2|Bacteria,2GMDF@201174|Actinobacteria,4DAN4@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_792034_0	103733.JNYO01000008_gene5444	1.945e-183	578.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DYUI@85010|Pseudonocardiales	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
TLS3_k127_792034_1	1089545.KB913037_gene2639	1.037e-152	488.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4E0CH@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_792034_4	1120948.KB903229_gene5332	2.599e-56	199.0	COG0599@1|root,COG0599@2|Bacteria,2GITB@201174|Actinobacteria,4E4J2@85010|Pseudonocardiales	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	pcaC	-	3.1.1.24,4.1.1.44	ko:K01607,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,CMD
TLS3_k127_792034_5	1120948.KB903229_gene5331	1.153e-48	179.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4DZ4W@85010|Pseudonocardiales	201174|Actinobacteria	F	3-carboxy-cis,cis-muconate cycloisomerase	pcaB	-	5.5.1.2	ko:K01857	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03307	RC00902	ko00000,ko00001,ko01000	-	-	-	ADSL_C,Lyase_1
TLS3_k127_7922318_1	1120948.KB903223_gene217	1.283e-61	232.0	COG2207@1|root,COG2207@2|Bacteria,2IBP1@201174|Actinobacteria,4E4FU@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
TLS3_k127_7922318_4	1237500.ANBA01000011_gene3449	8.341e-35	136.0	COG2076@1|root,COG2076@2|Bacteria,2IKQZ@201174|Actinobacteria,4EKHS@85012|Streptosporangiales	201174|Actinobacteria	P	Small Multidrug Resistance protein	-	-	-	ko:K03297	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
TLS3_k127_7922318_3	1246448.ANAZ01000002_gene4063	1.101e-37	150.0	COG3226@1|root,COG3226@2|Bacteria,2HUE7@201174|Actinobacteria	201174|Actinobacteria	K	TetR Family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_7922318_2	1120948.KB903243_gene2604	4.172e-44	171.0	COG3025@1|root,COG3025@2|Bacteria,2IN8R@201174|Actinobacteria	201174|Actinobacteria	S	triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
TLS3_k127_7922318_0	1121017.AUFG01000003_gene3343	2.884e-79	270.0	COG0491@1|root,COG0491@2|Bacteria,2H8JM@201174|Actinobacteria,4FG88@85021|Intrasporangiaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Lactamase_B
TLS3_k127_7929534_0	1120948.KB903229_gene4994	6.397e-160	508.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,4DYGT@85010|Pseudonocardiales	201174|Actinobacteria	D	PFAM Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
TLS3_k127_7929534_1	1120948.KB903229_gene4993	6.705e-79	282.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria,4E064@85010|Pseudonocardiales	201174|Actinobacteria	D	PFAM Anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
TLS3_k127_7945116_1	1120948.KB903243_gene2670	3.817e-157	500.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4DZZ7@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
TLS3_k127_7945116_0	1120948.KB903243_gene2671	2.966e-191	616.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4E05M@85010|Pseudonocardiales	201174|Actinobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
TLS3_k127_7945116_4	1268303.RHODMAR_4065	7.817e-62	219.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4FUPK@85025|Nocardiaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
TLS3_k127_7945116_3	1120948.KB903243_gene2679	3.947e-90	316.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4E1FI@85010|Pseudonocardiales	201174|Actinobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
TLS3_k127_7945116_2	1120948.KB903243_gene2680	3.427e-99	329.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4E0P0@85010|Pseudonocardiales	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
TLS3_k127_7945116_5	882082.SaccyDRAFT_4318	1.446e-11	66.0	COG0488@1|root,COG0488@2|Bacteria,2GJ5M@201174|Actinobacteria,4DY6K@85010|Pseudonocardiales	201174|Actinobacteria	S	of ABC transporters with duplicated ATPase	yjjK	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
TLS3_k127_7946008_0	1121946.AUAX01000002_gene300	0.0	1214.0	COG0110@1|root,COG1020@1|root,COG0110@2|Bacteria,COG1020@2|Bacteria,2I8TI@201174|Actinobacteria,4DBKJ@85008|Micromonosporales	201174|Actinobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Hexapep,Hexapep_2,PP-binding
TLS3_k127_7953001_0	1120948.KB903240_gene3956	3.175e-268	838.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4DXVE@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
TLS3_k127_7953001_3	1120948.KB903240_gene3957	3.727e-44	162.0	2EGGE@1|root,33A8E@2|Bacteria,2I1AG@201174|Actinobacteria,4E6FE@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7953001_2	1120948.KB903240_gene3958	9.408e-51	184.0	COG4768@1|root,COG4768@2|Bacteria,2II1J@201174|Actinobacteria,4E3ET@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF948)	-	-	-	-	-	-	-	-	-	-	-	-	DUF948
TLS3_k127_7953001_1	1120948.KB903240_gene3959	8.972e-124	400.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4DYAB@85010|Pseudonocardiales	201174|Actinobacteria	L	ATPase family associated with various cellular activities (AAA)	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
TLS3_k127_7975399_7	1157634.KB912966_gene2193	3.655e-36	141.0	COG1917@1|root,COG1917@2|Bacteria,2IQI4@201174|Actinobacteria	201174|Actinobacteria	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_7975399_8	1352941.M877_01005	1.242e-35	138.0	2D2PF@1|root,32TD7@2|Bacteria,2IIE0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_7975399_5	1449347.JQLN01000004_gene7247	7.351e-74	258.0	COG3393@1|root,COG3393@2|Bacteria,2GMQC@201174|Actinobacteria,2M2WW@2063|Kitasatospora	201174|Actinobacteria	S	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FR47
TLS3_k127_7975399_3	2074.JNYD01000024_gene2839	2.901e-158	508.0	COG2141@1|root,COG2141@2|Bacteria,2GJN5@201174|Actinobacteria,4E140@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_7975399_0	1120948.KB903247_gene4562	1.631e-241	756.0	COG2141@1|root,COG2141@2|Bacteria,2GJAN@201174|Actinobacteria,4E08X@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_7975399_2	1120948.KB903247_gene4560	5.831e-197	634.0	COG0626@1|root,COG0626@2|Bacteria,2GNZH@201174|Actinobacteria,4E1YC@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Cys Met metabolism	megL	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
TLS3_k127_7975399_6	1120948.KB903247_gene4556	3.501e-71	244.0	COG1765@1|root,COG1765@2|Bacteria,2IJNX@201174|Actinobacteria	201174|Actinobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
TLS3_k127_7975399_4	43354.JOIJ01000005_gene2144	2.204e-121	399.0	COG2175@1|root,COG2175@2|Bacteria,2GNUC@201174|Actinobacteria,4DZPU@85010|Pseudonocardiales	201174|Actinobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	ko:K22303	-	-	-	-	ko00000,ko01000	-	-	-	TauD
TLS3_k127_7975399_9	1452536.JARE01000047_gene2436	5.458e-05	49.0	COG3491@1|root,COG3491@2|Bacteria,2GT52@201174|Actinobacteria,4FKDK@85023|Microbacteriaceae	201174|Actinobacteria	C	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
TLS3_k127_7975399_1	2074.JNYD01000003_gene3949	8.654e-234	731.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4DZVP@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
TLS3_k127_7979808_0	1123024.AUII01000022_gene129	3.592e-135	465.0	COG2197@1|root,COG2197@2|Bacteria,2I321@201174|Actinobacteria,4EF7G@85010|Pseudonocardiales	201174|Actinobacteria	KT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_7980449_11	1146883.BLASA_4233	7.741e-08	57.0	COG0530@1|root,COG0530@2|Bacteria	2|Bacteria	P	calcium, potassium:sodium antiporter activity	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
TLS3_k127_7980449_7	1146883.BLASA_4233	4.649e-40	151.0	COG0530@1|root,COG0530@2|Bacteria	2|Bacteria	P	calcium, potassium:sodium antiporter activity	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
TLS3_k127_7980449_4	675635.Psed_2972	2.467e-166	530.0	COG2376@1|root,COG2376@2|Bacteria,2GJV9@201174|Actinobacteria,4DYRQ@85010|Pseudonocardiales	201174|Actinobacteria	G	Dihydroxyacetone kinase DhaK, subunit	dhaK	-	2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15	ko:K00863,ko:K05878	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	M00344	R01011,R01012,R01059	RC00002,RC00015,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Dak1
TLS3_k127_7980449_6	675635.Psed_2973	3.217e-74	271.0	COG1461@1|root,COG1461@2|Bacteria,2HEQ9@201174|Actinobacteria,4E2P5@85010|Pseudonocardiales	201174|Actinobacteria	S	Dihydroxyacetone kinase	dhaL	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
TLS3_k127_7980449_3	1123023.JIAI01000002_gene4894	5.39e-241	771.0	COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4DXBS@85010|Pseudonocardiales	201174|Actinobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N,PTS-HPr
TLS3_k127_7980449_5	2074.JNYD01000003_gene3446	7.268e-144	459.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,4E1IY@85010|Pseudonocardiales	201174|Actinobacteria	S	Polyphosphate kinase 2 (PPK2)	ppk2	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005525,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006183,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030808,GO:0031323,GO:0031326,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046777,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051704,GO:0055086,GO:0062012,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0080090,GO:0090407,GO:0097159,GO:0097367,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
TLS3_k127_7980449_12	1206730.BAGA01000093_gene454	0.0003521	45.0	COG1544@1|root,COG1544@2|Bacteria,2IB6N@201174|Actinobacteria,4FXI0@85025|Nocardiaceae	201174|Actinobacteria	J	Sigma 54 modulation/S30EA ribosomal protein C terminus	-	-	-	-	-	-	-	-	-	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
TLS3_k127_7980449_9	405948.SACE_2426	2.754e-25	113.0	2EH65@1|root,3351X@2|Bacteria,2GQUG@201174|Actinobacteria,4E74D@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF1876)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1876
TLS3_k127_7980449_0	1120948.KB903246_gene3242	0.0	1158.0	COG1643@1|root,COG1643@2|Bacteria,2GMAW@201174|Actinobacteria,4DYCE@85010|Pseudonocardiales	201174|Actinobacteria	L	ATP-dependent helicase HrpB	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
TLS3_k127_7980449_8	1120948.KB903218_gene2058	1.292e-32	147.0	COG3431@1|root,COG3431@2|Bacteria,2GQM3@201174|Actinobacteria	201174|Actinobacteria	S	Sensors of blue-light using FAD	-	-	-	-	-	-	-	-	-	-	-	-	BLUF
TLS3_k127_7980449_1	1123023.JIAI01000001_gene6229	1.055e-269	842.0	COG0365@1|root,COG0365@2|Bacteria,2GJSQ@201174|Actinobacteria	201174|Actinobacteria	I	AMP-dependent synthetase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_7980449_2	263358.VAB18032_21090	8.466e-259	804.0	COG0069@1|root,COG0069@2|Bacteria,2GME2@201174|Actinobacteria,4DC09@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the glutamate synthase family	gltB_1	-	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	Glu_synthase
TLS3_k127_7980449_10	1048339.KB913029_gene2397	6.031e-12	66.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4ETX4@85013|Frankiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
TLS3_k127_8002027_1	1120948.KB903218_gene1862	7.68e-18	89.0	COG1525@1|root,COG1525@2|Bacteria,2I7I9@201174|Actinobacteria	201174|Actinobacteria	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8002027_0	1120948.KB903218_gene1861	2.715e-122	400.0	COG2124@1|root,COG2124@2|Bacteria,2GNJI@201174|Actinobacteria,4DXRC@85010|Pseudonocardiales	201174|Actinobacteria	Q	cytochrome P450	eryK	GO:0000166,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0019748,GO:0020037,GO:0030638,GO:0030639,GO:0033067,GO:0033068,GO:0036094,GO:0044237,GO:0044249,GO:0044550,GO:0046483,GO:0046906,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901363,GO:1901576	1.14.13.154	ko:K14370	ko00522,ko01052,ko01130,map00522,map01052,map01130	M00774	R05521,R05522	RC01892	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	-	-	-	p450
TLS3_k127_8024918_2	1120948.KB903218_gene2177	1.397e-154	496.0	COG0342@1|root,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4DYZP@85010|Pseudonocardiales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
TLS3_k127_8024918_1	1120948.KB903218_gene2178	2.653e-169	544.0	COG0341@1|root,COG0341@2|Bacteria,2GJRS@201174|Actinobacteria,4E10T@85010|Pseudonocardiales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
TLS3_k127_8024918_3	1120948.KB903218_gene2179	2.971e-60	234.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4E3Z9@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
TLS3_k127_8024918_0	1120948.KB903218_gene2181	0.0	1079.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4E0NQ@85010|Pseudonocardiales	201174|Actinobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
TLS3_k127_8025537_2	1120948.KB903217_gene1122	1.733e-07	57.0	COG3945@1|root,COG3945@2|Bacteria,2IDKN@201174|Actinobacteria,4E58X@85010|Pseudonocardiales	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
TLS3_k127_8025537_1	1120948.KB903217_gene1123	1.649e-46	184.0	2EEQX@1|root,338IM@2|Bacteria,2IFKH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8025537_0	1120948.KB903217_gene1124	3.134e-50	179.0	COG0316@1|root,COG0316@2|Bacteria,2GR0Z@201174|Actinobacteria,4E7G9@85010|Pseudonocardiales	201174|Actinobacteria	S	HesB YadR YfhF-family protein	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
TLS3_k127_8036469_9	1120948.KB903247_gene4481	1.548e-70	242.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4DXZ0@85010|Pseudonocardiales	201174|Actinobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
TLS3_k127_8036469_4	1120948.KB903247_gene4482	2.064e-173	560.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,4DX9V@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
TLS3_k127_8036469_3	1120948.KB903247_gene4483	5.427e-183	603.0	COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4DZ1E@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
TLS3_k127_8036469_1	1120948.KB903247_gene4486	2.07e-257	804.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4E0VC@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	fadD5	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_8036469_8	1123023.JIAI01000020_gene2126	7.919e-87	305.0	COG3217@1|root,COG3217@2|Bacteria,2GND9@201174|Actinobacteria,4E4QC@85010|Pseudonocardiales	201174|Actinobacteria	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
TLS3_k127_8036469_5	1120948.KB903247_gene4489	1.894e-143	500.0	2AQY0@1|root,31G6M@2|Bacteria,2IEYJ@201174|Actinobacteria,4DY1Q@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8036469_0	1120948.KB903247_gene4488	0.0	1260.0	COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,4DXPF@85010|Pseudonocardiales	201174|Actinobacteria	L	Type III restriction enzyme, res subunit	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
TLS3_k127_8036469_10	1209984.BN978_06689	2.621e-68	235.0	2DK0G@1|root,30823@2|Bacteria,2IJ7K@201174|Actinobacteria,238KB@1762|Mycobacteriaceae	201174|Actinobacteria	S	Rifampin ADP-ribosyl transferase	arr	-	-	ko:K19062	-	-	-	-	ko00000,ko01504	-	-	-	Arr-ms
TLS3_k127_8036469_6	1435356.Y013_06615	7.816e-134	434.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4FXXE@85025|Nocardiaceae	201174|Actinobacteria	S	AAA domain (Cdc48 subfamily)	clpL	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
TLS3_k127_8036469_2	1120948.KB903247_gene4494	3.056e-206	681.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,4DYBU@85010|Pseudonocardiales	201174|Actinobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
TLS3_k127_8036469_7	1120948.KB903247_gene4495	6.629e-103	337.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4E0CB@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
TLS3_k127_8036469_11	1120948.KB903244_gene2918	3.413e-38	148.0	COG3576@1|root,COG3576@2|Bacteria,2II3S@201174|Actinobacteria,4E4Q4@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
TLS3_k127_8036469_12	1120948.KB903247_gene4497	1.487e-11	64.0	COG4398@1|root,COG4398@2|Bacteria,2I3VH@201174|Actinobacteria,4E1JP@85010|Pseudonocardiales	201174|Actinobacteria	S	FIST N domain	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
TLS3_k127_8058541_2	1120948.KB903224_gene329	2.465e-164	521.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4DXG2@85010|Pseudonocardiales	201174|Actinobacteria	C	Malic enzyme	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
TLS3_k127_8058541_6	1120948.KB903224_gene328	5.098e-77	270.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4E2K3@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
TLS3_k127_8058541_7	1120948.KB903224_gene327	1.381e-74	255.0	COG0521@1|root,COG0521@2|Bacteria,2II28@201174|Actinobacteria,4DZNU@85010|Pseudonocardiales	201174|Actinobacteria	H	TIGRFAM molybdenum cofactor synthesis	mog	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaE
TLS3_k127_8058541_8	1120948.KB903224_gene326	1.388e-62	223.0	COG0314@1|root,COG0314@2|Bacteria,2IQ9F@201174|Actinobacteria,4E4U8@85010|Pseudonocardiales	201174|Actinobacteria	H	MoaE protein	moaE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
TLS3_k127_8058541_10	1120948.KB903224_gene325	4.203e-43	169.0	COG1388@1|root,COG1388@2|Bacteria,2GQ1M@201174|Actinobacteria,4E2JD@85010|Pseudonocardiales	201174|Actinobacteria	M	Lysin motif	rpfA	-	-	ko:K21687,ko:K21691	-	-	-	-	ko00000	-	GH23	-	DUF3235,LysM,NLPC_P60,Transglycosylas
TLS3_k127_8058541_9	1120948.KB903224_gene325	1.218e-59	214.0	COG1388@1|root,COG1388@2|Bacteria,2GQ1M@201174|Actinobacteria,4E2JD@85010|Pseudonocardiales	201174|Actinobacteria	M	Lysin motif	rpfA	-	-	ko:K21687,ko:K21691	-	-	-	-	ko00000	-	GH23	-	DUF3235,LysM,NLPC_P60,Transglycosylas
TLS3_k127_8058541_3	1120948.KB903224_gene324	1.875e-153	490.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4DX6A@85010|Pseudonocardiales	201174|Actinobacteria	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
TLS3_k127_8058541_1	1120948.KB903224_gene323	4.627e-183	607.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,4DZRT@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein containing von Willebrand factor type A (VWA) domain	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
TLS3_k127_8058541_0	1123023.JIAI01000008_gene1347	1.144e-189	598.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria,4E0N1@85010|Pseudonocardiales	201174|Actinobacteria	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
TLS3_k127_8058541_4	680198.SCAB_88131	1.384e-125	409.0	COG0500@1|root,COG2226@2|Bacteria,2GM2N@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
TLS3_k127_8058541_5	1150599.MPHLEI_22739	2.612e-117	388.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,235YH@1762|Mycobacteriaceae	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
TLS3_k127_8060442_4	1120948.KB903219_gene733	1.692e-77	265.0	COG0697@1|root,COG0697@2|Bacteria,2GRXH@201174|Actinobacteria,4E5V7@85010|Pseudonocardiales	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8060442_3	1120948.KB903240_gene4002	5.46e-79	282.0	COG4325@1|root,COG4325@2|Bacteria,2GM70@201174|Actinobacteria,4E3UX@85010|Pseudonocardiales	201174|Actinobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8060442_0	526225.Gobs_2319	0.0	1480.0	COG1190@1|root,COG2898@1|root,COG1190@2|Bacteria,COG2898@2|Bacteria,2GKE0@201174|Actinobacteria,4ERF1@85013|Frankiales	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	-	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF2156,tRNA-synt_2,tRNA_anti-codon
TLS3_k127_8060442_1	1283283.ATXA01000012_gene4781	9.243e-209	667.0	COG0531@1|root,COG0531@2|Bacteria,2HMMA@201174|Actinobacteria,4EU95@85013|Frankiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	ko:K20265	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.3.7.1,2.A.3.7.3	-	-	AA_permease_2
TLS3_k127_8060442_2	1120948.KB903219_gene734	4.615e-134	437.0	COG0627@1|root,COG0627@2|Bacteria,2GP6Q@201174|Actinobacteria,4E0VI@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
TLS3_k127_8060442_5	2074.JNYD01000015_gene4576	1.988e-37	146.0	COG2197@1|root,COG2197@2|Bacteria,2IP1K@201174|Actinobacteria,4EF2M@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
TLS3_k127_8062839_5	350058.Mvan_0163	2.29e-60	216.0	COG0346@1|root,COG0346@2|Bacteria,2IFUM@201174|Actinobacteria,238NS@1762|Mycobacteriaceae	2|Bacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	cadI	GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
TLS3_k127_8062839_1	1429046.RR21198_4075	8.007e-108	357.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4FYX8@85025|Nocardiaceae	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
TLS3_k127_8062839_3	1150864.MILUP08_43047	3.52e-92	314.0	COG0604@1|root,COG0604@2|Bacteria,2GRJM@201174|Actinobacteria,4DDVM@85008|Micromonosporales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
TLS3_k127_8062839_8	1150864.MILUP08_43046	3.305e-34	139.0	COG1733@1|root,COG1733@2|Bacteria,2IQNN@201174|Actinobacteria,4DEK2@85008|Micromonosporales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
TLS3_k127_8062839_6	1127134.NOCYR_0220	8.765e-45	169.0	COG1309@1|root,COG1309@2|Bacteria,2GPBQ@201174|Actinobacteria,4FZ9T@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_8062839_4	1078020.KEK_01905	2.023e-60	228.0	COG1073@1|root,COG1073@2|Bacteria,2GNB6@201174|Actinobacteria,2366C@1762|Mycobacteriaceae	201174|Actinobacteria	S	Alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
TLS3_k127_8062839_7	1120960.ATXG01000003_gene1823	2.144e-36	144.0	2E1QD@1|root,32X0Q@2|Bacteria,2IRI9@201174|Actinobacteria,4FT2X@85023|Microbacteriaceae	201174|Actinobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
TLS3_k127_8062839_9	1120948.KB903247_gene4457	1.962e-25	120.0	COG2020@1|root,COG2020@2|Bacteria,2HPCN@201174|Actinobacteria,4E7YM@85010|Pseudonocardiales	201174|Actinobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
TLS3_k127_8062839_10	1341157.RF007C_10740	1.402e-11	76.0	COG1605@1|root,COG1605@2|Bacteria,1VHNI@1239|Firmicutes,24RYK@186801|Clostridia,3WQ6Z@541000|Ruminococcaceae	186801|Clostridia	E	Chorismate mutase type II	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	CM_2
TLS3_k127_8062839_0	1120948.KB903244_gene3082	8.068e-206	646.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4DX6Q@85010|Pseudonocardiales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	adh	-	1.1.1.1	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10703	RC00050,RC00087,RC00088,RC00099,RC00116,RC00545,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
TLS3_k127_8062839_2	867903.ThesuDRAFT_01341	1.117e-104	356.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
TLS3_k127_8066732_0	1120948.KB903243_gene2286	1.069e-196	629.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,4DZV0@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
TLS3_k127_8066732_4	1120948.KB903243_gene2287	2.286e-50	181.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4E5EK@85010|Pseudonocardiales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB2	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
TLS3_k127_8066732_3	1120948.KB903243_gene2288	1.115e-70	248.0	COG1994@1|root,COG1994@2|Bacteria,2GM8E@201174|Actinobacteria,4E07G@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Peptidase family M50	rip2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
TLS3_k127_8066732_2	1120948.KB903243_gene2289	1.179e-150	496.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria,4DZIQ@85010|Pseudonocardiales	201174|Actinobacteria	S	LPPG Fo 2-phospho-L-lactate transferase	cofD	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0043743,GO:0044237,GO:0044249,GO:0051186,GO:0051188	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
TLS3_k127_8066732_1	1120948.KB903243_gene2290	1.726e-189	602.0	COG0778@1|root,COG1478@1|root,COG0778@2|Bacteria,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,4DX67@85010|Pseudonocardiales	201174|Actinobacteria	C	F420-0 Gamma-glutamyl ligase	fbiB	GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase,Nitroreductase
TLS3_k127_8071198_0	258052.JNYV01000003_gene5104	3.774e-296	920.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,2M113@2063|Kitasatospora	201174|Actinobacteria	M	SIS domain	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
TLS3_k127_8071198_2	1120948.KB903217_gene1592	1.305e-120	395.0	COG0412@1|root,COG0412@2|Bacteria,2GKWS@201174|Actinobacteria,4E05E@85010|Pseudonocardiales	201174|Actinobacteria	Q	Chlorophyllase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase,Chlorophyllase2,DLH
TLS3_k127_8071198_1	1268303.RHODMAR_3879	3.406e-146	473.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4FVR3@85025|Nocardiaceae	201174|Actinobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	GO:0008150,GO:0040007	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
TLS3_k127_8076813_3	1120948.KB903217_gene1503	1.711e-125	406.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4DXE3@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_8076813_4	1120948.KB903217_gene1500	9.105e-96	319.0	COG1309@1|root,COG1309@2|Bacteria,2GMVQ@201174|Actinobacteria,4E3GK@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_8076813_5	1120948.KB903218_gene1934	2.662e-59	224.0	COG1309@1|root,COG1309@2|Bacteria,2IGE6@201174|Actinobacteria,4E4C6@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_8076813_6	1869.MB27_15545	4.168e-44	184.0	COG4689@1|root,COG4689@2|Bacteria,2IRMQ@201174|Actinobacteria,4DEBD@85008|Micromonosporales	201174|Actinobacteria	Q	Acetoacetate decarboxylase (ADC)	-	-	4.1.1.4	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	M00088	R01366	RC00040	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC
TLS3_k127_8076813_0	1120948.KB903218_gene1935	3.508e-253	794.0	COG2303@1|root,COG2303@2|Bacteria,2GJ3J@201174|Actinobacteria,4E1WB@85010|Pseudonocardiales	201174|Actinobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
TLS3_k127_8076813_1	1120948.KB903217_gene1499	2.215e-232	726.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4DXDP@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the thiolase family	fadA1	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
TLS3_k127_8076813_2	1120948.KB903217_gene1498	1.386e-201	637.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2GJ50@201174|Actinobacteria,4E0TU@85010|Pseudonocardiales	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	fadB	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
TLS3_k127_8088113_5	1172188.KB911820_gene2418	3.316e-45	169.0	COG4101@1|root,COG4101@2|Bacteria,2II42@201174|Actinobacteria,4FGN5@85021|Intrasporangiaceae	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
TLS3_k127_8088113_1	1120948.KB903248_gene4257	1.338e-168	537.0	COG0039@1|root,COG0039@2|Bacteria,2GJHS@201174|Actinobacteria,4DYMT@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
TLS3_k127_8088113_0	1120948.KB903248_gene4258	7.443e-184	597.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4E2D5@85010|Pseudonocardiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
TLS3_k127_8088113_6	1120948.KB903248_gene4259	1.026e-33	149.0	2FHDP@1|root,3497V@2|Bacteria,2GRCC@201174|Actinobacteria,4ECGZ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8088113_2	1179773.BN6_68860	9.028e-146	477.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4DZW0@85010|Pseudonocardiales	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
TLS3_k127_8088113_4	1120948.KB903248_gene4261	1.469e-59	225.0	COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,4E3F6@85010|Pseudonocardiales	201174|Actinobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
TLS3_k127_8088113_3	1120948.KB903248_gene4262	1.765e-100	336.0	COG3263@1|root,COG3263@2|Bacteria,2GJ9B@201174|Actinobacteria,4E1CC@85010|Pseudonocardiales	201174|Actinobacteria	P	NhaP-type Na (K ) H antiporter	cvrA	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
TLS3_k127_8091547_0	1120948.KB903217_gene1168	3.724e-313	966.0	COG0433@1|root,COG0433@2|Bacteria,2GMYE@201174|Actinobacteria,4DZQ7@85010|Pseudonocardiales	201174|Actinobacteria	L	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
TLS3_k127_8094198_0	1445613.JALM01000036_gene2875	3.604e-95	335.0	COG2025@1|root,COG2025@2|Bacteria,2I9CI@201174|Actinobacteria,4E0Z1@85010|Pseudonocardiales	201174|Actinobacteria	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ETF,ETF_alpha
TLS3_k127_8094198_1	1445613.JALM01000036_gene2874	3.142e-93	312.0	COG2086@1|root,COG2086@2|Bacteria,2IB9F@201174|Actinobacteria,4E43Q@85010|Pseudonocardiales	201174|Actinobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
TLS3_k127_8094198_3	1114959.SZMC14600_09728	5.224e-24	101.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4E1F5@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the GcvT family	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
TLS3_k127_8124233_3	675635.Psed_4730	1.301e-16	80.0	COG0739@1|root,COG0739@2|Bacteria,2IQ64@201174|Actinobacteria,4E5H3@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
TLS3_k127_8124233_1	1120948.KB903245_gene3435	3.591e-125	412.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4DZK1@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	whiG	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
TLS3_k127_8124233_0	1120948.KB903245_gene3436	4.52e-137	447.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4DYRU@85010|Pseudonocardiales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
TLS3_k127_8124233_2	1120948.KB903245_gene3437	9.161e-90	305.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,4DYR3@85010|Pseudonocardiales	201174|Actinobacteria	LU	PFAM DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
TLS3_k127_8129085_0	710687.KI912270_gene1766	0.0	1194.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,233DM@1762|Mycobacteriaceae	201174|Actinobacteria	K	involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,Trans_reg_C
TLS3_k127_8129085_18	247639.MGP2080_06792	1.636e-20	101.0	COG1296@1|root,COG1296@2|Bacteria	2|Bacteria	E	L-valine transmembrane transporter activity	azlC	-	-	-	-	-	-	-	-	-	-	-	AzlC
TLS3_k127_8129085_19	1828.JOKB01000028_gene2296	4.639e-16	91.0	COG3631@1|root,COG3631@2|Bacteria,2GQJQ@201174|Actinobacteria,4G54I@85025|Nocardiaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
TLS3_k127_8129085_7	1283283.ATXA01000016_gene52	4.258e-91	313.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,2GMG7@201174|Actinobacteria,4ERWU@85013|Frankiales	201174|Actinobacteria	KT	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
TLS3_k127_8129085_1	1120948.KB903225_gene5602	0.0	1144.0	COG1199@1|root,COG1199@2|Bacteria,2GKT8@201174|Actinobacteria,4E0JP@85010|Pseudonocardiales	201174|Actinobacteria	KL	helicase	dinG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
TLS3_k127_8129085_11	1120948.KB903225_gene5598	2.57e-80	271.0	COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,4E2XZ@85010|Pseudonocardiales	201174|Actinobacteria	Q	PFAM Isochorismatase	pncA	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
TLS3_k127_8129085_2	1120948.KB903225_gene5596	7.448e-212	664.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4DXVH@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034355,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C
TLS3_k127_8129085_17	1120948.KB903225_gene5595	5.005e-43	164.0	COG2127@1|root,COG2127@2|Bacteria,2IQ3Z@201174|Actinobacteria,4E4YJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
TLS3_k127_8129085_12	1120948.KB903225_gene5594	1.747e-76	259.0	2E4AX@1|root,32Z6K@2|Bacteria,2GW4T@201174|Actinobacteria,4E31H@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF2017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2017
TLS3_k127_8129085_13	103733.JNYO01000033_gene7263	8.59e-76	256.0	COG1310@1|root,COG1310@2|Bacteria,2IFB5@201174|Actinobacteria,4E2VD@85010|Pseudonocardiales	201174|Actinobacteria	S	metal-dependent protease of the PAD1 JAB1 superfamily	mec	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
TLS3_k127_8129085_16	1120948.KB903225_gene5592	6.585e-46	177.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4E5BP@85010|Pseudonocardiales	201174|Actinobacteria	H	TIGRFAM MoaD family protein	cysO	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
TLS3_k127_8129085_3	1120948.KB903225_gene5591	1.272e-191	602.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4DX6P@85010|Pseudonocardiales	201174|Actinobacteria	E	Cysteine synthase	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113	ko:K21148	ko04122,map04122	-	R10610	RC03225	ko00000,ko00001,ko01000	-	-	-	PALP
TLS3_k127_8129085_14	1120948.KB903225_gene5590	4.921e-67	247.0	COG0705@1|root,COG0705@2|Bacteria,2HCGE@201174|Actinobacteria,4E3EV@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
TLS3_k127_8129085_6	1120948.KB903225_gene5589	5.295e-120	389.0	COG1234@1|root,COG1234@2|Bacteria,2GMEX@201174|Actinobacteria,4DYEQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Beta-lactamase	yhfI	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
TLS3_k127_8129085_4	1120948.KB903225_gene5588	4.478e-168	541.0	COG0477@1|root,COG0477@2|Bacteria,2I31V@201174|Actinobacteria,4E1WF@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_8129085_5	1120948.KB903225_gene5587	1.574e-140	449.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4DYGI@85010|Pseudonocardiales	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
TLS3_k127_8129085_8	1120948.KB903225_gene5586	4.895e-88	308.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4E0TE@85010|Pseudonocardiales	201174|Actinobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
TLS3_k127_8129085_9	1120948.KB903225_gene5585	4.536e-85	286.0	COG2813@1|root,COG2813@2|Bacteria,2IFG7@201174|Actinobacteria,4E5AG@85010|Pseudonocardiales	201174|Actinobacteria	J	Methyltransferase small domain	rsmC	-	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS
TLS3_k127_8129085_10	1120948.KB903225_gene5584	8.964e-83	293.0	COG0596@1|root,COG0596@2|Bacteria,2GNBJ@201174|Actinobacteria,4EB41@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
TLS3_k127_8129085_15	2074.JNYD01000022_gene1507	1.924e-57	211.0	COG1403@1|root,COG1403@2|Bacteria,2GYWG@201174|Actinobacteria	201174|Actinobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_3
TLS3_k127_8132439_4	1179773.BN6_00010	1.369e-121	420.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4E04J@85010|Pseudonocardiales	201174|Actinobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
TLS3_k127_8132439_11	1123023.JIAI01000005_gene532	1.785e-16	82.0	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria,4E6S5@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
TLS3_k127_8132439_9	1120948.KB903217_gene985	2.948e-32	131.0	COG0594@1|root,COG0594@2|Bacteria,2GR42@201174|Actinobacteria,4E5FQ@85010|Pseudonocardiales	201174|Actinobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0008150,GO:0040007	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
TLS3_k127_8132439_8	570268.ANBB01000058_gene4267	1.064e-60	226.0	COG2242@1|root,COG2242@2|Bacteria,2GMWW@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
TLS3_k127_8132439_10	675635.Psed_6690	1.939e-27	129.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4E5Q0@85010|Pseudonocardiales	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
TLS3_k127_8132439_2	1120948.KB903217_gene987	1.996e-140	457.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,4DXNV@85010|Pseudonocardiales	201174|Actinobacteria	U	Preprotein translocase subunit YidC	yidC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
TLS3_k127_8132439_7	1120948.KB903217_gene988	1.539e-72	258.0	COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,4E2XI@85010|Pseudonocardiales	201174|Actinobacteria	S	RNA-binding protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	KH_4,R3H
TLS3_k127_8132439_6	1120948.KB903217_gene989	3.737e-89	303.0	COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,4E30C@85010|Pseudonocardiales	201174|Actinobacteria	M	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
TLS3_k127_8132439_1	1120948.KB903217_gene990	1.528e-167	533.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4DXU2@85010|Pseudonocardiales	201174|Actinobacteria	D	chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
TLS3_k127_8132439_3	1179773.BN6_85390	8.521e-130	425.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4DXY2@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the ParB family	parB	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
TLS3_k127_8132439_5	1120948.KB903217_gene994	1.217e-114	376.0	COG3153@1|root,COG3153@2|Bacteria,2GNNB@201174|Actinobacteria,4DXW4@85010|Pseudonocardiales	201174|Actinobacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
TLS3_k127_8132439_0	1120948.KB903217_gene995	1.231e-202	636.0	COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria,2GPA9@201174|Actinobacteria,4E10H@85010|Pseudonocardiales	201174|Actinobacteria	M	N-acetylmuramoyl-L-alanine amidase	cwlM	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,PG_binding_1
TLS3_k127_813575_2	1032480.MLP_34790	4.135e-70	242.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4DNW9@85009|Propionibacteriales	201174|Actinobacteria	P	Ammonium Transporter Family	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	iNJ661.Rv2920c	Ammonium_transp
TLS3_k127_813575_0	1120948.KB903245_gene3456	2.603e-180	596.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4DZIT@85010|Pseudonocardiales	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
TLS3_k127_813575_3	1120948.KB903245_gene3457	1.56e-29	124.0	2C2H6@1|root,337ZN@2|Bacteria,2GS3J@201174|Actinobacteria,4ED4M@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_813575_1	1120948.KB903245_gene3458	2.058e-174	552.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4DYMX@85010|Pseudonocardiales	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
TLS3_k127_8181598_2	1120948.KB903217_gene1433	3.357e-113	377.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,4E0ID@85010|Pseudonocardiales	201174|Actinobacteria	O	PFAM Cytochrome C biogenesis protein transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
TLS3_k127_8181598_0	1120948.KB903217_gene1434	9.389e-236	751.0	COG1333@1|root,COG1333@2|Bacteria,2GMGH@201174|Actinobacteria,4DZH2@85010|Pseudonocardiales	201174|Actinobacteria	O	ResB protein required for cytochrome c biosynthesis	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
TLS3_k127_8181598_1	1120948.KB903217_gene1435	7.586e-160	511.0	COG0755@1|root,COG0755@2|Bacteria,2GJR1@201174|Actinobacteria,4DXN9@85010|Pseudonocardiales	201174|Actinobacteria	O	Cytochrome c assembly protein	ccsB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
TLS3_k127_8203125_3	928724.SacglDRAFT_00661	3.568e-13	70.0	2FA44@1|root,342CZ@2|Bacteria,2IRUK@201174|Actinobacteria,4E5S9@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8203125_2	1120948.KB903243_gene2314	9.945e-101	362.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,4DY3G@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM histidinol-phosphate phosphatase HisN, inositol monophosphatase family	hisN	-	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
TLS3_k127_8203125_1	1120948.KB903243_gene2313	5.695e-122	393.0	COG0745@1|root,COG0745@2|Bacteria,2GP1I@201174|Actinobacteria,4E1R6@85010|Pseudonocardiales	201174|Actinobacteria	T	Response regulator receiver	vicR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
TLS3_k127_8203125_0	1120948.KB903243_gene2312	1.162e-192	608.0	COG0642@1|root,COG2205@2|Bacteria,2I3HN@201174|Actinobacteria,4DY7C@85010|Pseudonocardiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
TLS3_k127_8220512_2	1120948.KB903217_gene1084	3.089e-114	372.0	2CC51@1|root,2Z7IU@2|Bacteria,2GM14@201174|Actinobacteria,4E0QQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2397
TLS3_k127_8220512_1	1120948.KB903217_gene1085	1.713e-189	598.0	28HUD@1|root,2Z813@2|Bacteria,2ICFF@201174|Actinobacteria,4DZKZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2398)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2397,DUF2398
TLS3_k127_8220512_9	2074.JNYD01000009_gene5300	6.684e-38	145.0	COG0640@1|root,COG0640@2|Bacteria,2ISNZ@201174|Actinobacteria,4E5EH@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
TLS3_k127_8220512_7	675635.Psed_2043	1.25e-49	187.0	COG3832@1|root,COG3832@2|Bacteria,2IFFI@201174|Actinobacteria,4ECQX@85010|Pseudonocardiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
TLS3_k127_8220512_11	675635.Psed_6483	0.0002881	46.0	COG4924@1|root,COG4924@2|Bacteria,2GNHY@201174|Actinobacteria,4E5MA@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function N-terminus (DUF3323)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2399,DUF3323
TLS3_k127_8220512_5	1120948.KB903217_gene1087	5.215e-74	257.0	COG2981@1|root,COG2981@2|Bacteria,2GJZ4@201174|Actinobacteria,4E0AM@85010|Pseudonocardiales	201174|Actinobacteria	E	protein involved in cysteine biosynthesis	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
TLS3_k127_8220512_4	675635.Psed_3104	1.208e-82	282.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria,4E656@85010|Pseudonocardiales	201174|Actinobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
TLS3_k127_8220512_10	2074.JNYD01000007_gene2167	2.394e-23	110.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria,4E656@85010|Pseudonocardiales	201174|Actinobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
TLS3_k127_8220512_6	1120948.KB903217_gene1089	7.656e-68	238.0	COG0789@1|root,COG0789@2|Bacteria,2GKTU@201174|Actinobacteria,4E4BB@85010|Pseudonocardiales	201174|Actinobacteria	K	MerR, DNA binding	-	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
TLS3_k127_8220512_8	1172179.AUKV01000032_gene5194	6.744e-49	200.0	COG0431@1|root,COG0431@2|Bacteria,2GNFR@201174|Actinobacteria	201174|Actinobacteria	K	NAD(P)H-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
TLS3_k127_8220512_3	1120948.KB903217_gene1091	3.472e-101	345.0	2AUNZ@1|root,31KBW@2|Bacteria,2GP4I@201174|Actinobacteria,4E15W@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2786
TLS3_k127_8220512_0	1123024.AUII01000004_gene1503	0.0	1074.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,2HI92@201174|Actinobacteria,4DXAQ@85010|Pseudonocardiales	201174|Actinobacteria	L	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
TLS3_k127_822438_1	1120948.KB903217_gene1462	5.814e-187	631.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,4DYNI@85010|Pseudonocardiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
TLS3_k127_822438_0	1120948.KB903217_gene1461	0.0	1165.0	COG1034@1|root,COG1034@2|Bacteria,2GJGX@201174|Actinobacteria,4E093@85010|Pseudonocardiales	201174|Actinobacteria	C	TIGRFAM NADH-quinone oxidoreductase, chain G	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
TLS3_k127_822438_2	1068980.ARVW01000001_gene2641	1.54e-27	112.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4E01D@85010|Pseudonocardiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
TLS3_k127_824873_7	1120948.KB903219_gene658	7.008e-12	77.0	COG2267@1|root,COG2267@2|Bacteria,2GUBM@201174|Actinobacteria,4E4XS@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	phaB	-	3.1.1.76	ko:K22250	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
TLS3_k127_824873_5	1120948.KB903219_gene657	3.296e-47	172.0	COG1396@1|root,COG1396@2|Bacteria,2GPQW@201174|Actinobacteria,4EC3K@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
TLS3_k127_824873_0	1120948.KB903219_gene654	2.396e-271	845.0	COG3243@1|root,COG3243@2|Bacteria,2GNYP@201174|Actinobacteria,4E13S@85010|Pseudonocardiales	201174|Actinobacteria	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
TLS3_k127_824873_2	1120948.KB903219_gene653	1.06e-115	380.0	COG4976@1|root,COG4976@2|Bacteria,2IGUS@201174|Actinobacteria,4E3AJ@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
TLS3_k127_824873_3	1120948.KB903219_gene652	1.114e-71	254.0	2CCJS@1|root,32RVX@2|Bacteria,2IR2M@201174|Actinobacteria,4E6UM@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_824873_1	1385519.N801_14535	4.377e-172	552.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4FFAY@85021|Intrasporangiaceae	201174|Actinobacteria	C	COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid	lldD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	1.1.2.3,1.1.3.15	ko:K00101,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00196,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	iNJ661.Rv1872c	FMN_dh
TLS3_k127_824873_4	1120948.KB903245_gene3521	8.881e-61	224.0	COG0748@1|root,COG0748@2|Bacteria,2IIRE@201174|Actinobacteria,4E5TA@85010|Pseudonocardiales	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
TLS3_k127_824873_6	1120948.KB903243_gene2403	4.281e-17	94.0	COG0508@1|root,COG0508@2|Bacteria,2GQQK@201174|Actinobacteria,4EFB2@85010|Pseudonocardiales	201174|Actinobacteria	C	dehydrogenase complex catalyzes the overall conversion of	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_824873_9	1120948.KB903243_gene2404	4.475e-09	63.0	2ADQJ@1|root,313FX@2|Bacteria,2H0DG@201174|Actinobacteria,4E2J8@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8250422_5	345341.KUTG_02525	1.048e-21	98.0	COG0500@1|root,COG2226@2|Bacteria,2IDNA@201174|Actinobacteria,4E5M5@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_8250422_2	2074.JNYD01000022_gene1489	1.806e-93	316.0	COG2207@1|root,COG2207@2|Bacteria,2I3SB@201174|Actinobacteria,4E0KR@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
TLS3_k127_8250422_0	1120950.KB892774_gene1221	3.722e-119	409.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DPZV@85009|Propionibacteriales	201174|Actinobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08167	-	M00713,M00714	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3	-	-	MFS_1
TLS3_k127_8250422_4	1445613.JALM01000073_gene6865	4.989e-55	203.0	COG3832@1|root,COG3832@2|Bacteria,2HQ66@201174|Actinobacteria,4E35N@85010|Pseudonocardiales	201174|Actinobacteria	S	Pfam Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
TLS3_k127_8250422_3	469383.Cwoe_0328	3.94e-64	232.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
TLS3_k127_8250422_1	1120948.KB903218_gene1889	1.188e-94	315.0	COG0212@1|root,COG0212@2|Bacteria,2GM4X@201174|Actinobacteria,4E2I3@85010|Pseudonocardiales	201174|Actinobacteria	H	PFAM 5-formyltetrahydrofolate cyclo-ligase	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
TLS3_k127_8262715_6	298654.FraEuI1c_1372	8.292e-18	85.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
TLS3_k127_8262715_3	1122138.AQUZ01000065_gene4256	2.165e-75	263.0	COG2197@1|root,COG2197@2|Bacteria,2IFE7@201174|Actinobacteria,4DQ78@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_8262715_1	675635.Psed_1011	9.564e-115	389.0	COG2807@1|root,COG2807@2|Bacteria,2GP5W@201174|Actinobacteria,4EAH8@85010|Pseudonocardiales	201174|Actinobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K03449	-	-	-	-	ko00000,ko02000	2.A.1.17	-	-	MFS_1
TLS3_k127_8262715_0	1120948.KB903246_gene3325	6.324e-142	466.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4E0RW@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Aminotransferase class I and II	dapC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
TLS3_k127_8262715_4	1089546.AQUI01000002_gene3968	7.873e-62	216.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4098C@622450|Actinopolysporales	201174|Actinobacteria	C	4Fe-4S binding domain	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4
TLS3_k127_8262715_2	1120948.KB903246_gene3327	4.935e-110	369.0	2CEIX@1|root,32V0H@2|Bacteria,2IAXA@201174|Actinobacteria,4E22P@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8262715_7	1120948.KB903246_gene3331	0.000408	43.0	COG2120@1|root,COG2120@2|Bacteria,2GKUM@201174|Actinobacteria,4E0WC@85010|Pseudonocardiales	201174|Actinobacteria	S	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway	mshB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016137,GO:0016138,GO:0016787,GO:0016810,GO:0016811,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	3.5.1.103	ko:K15525	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
TLS3_k127_8268025_1	208439.AJAP_15780	1.248e-123	403.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4E2ZP@85010|Pseudonocardiales	201174|Actinobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3,1.5.99.4	ko:K03519,ko:K19818	ko00760,ko01120,map00760,map01120	M00810	R02860,R07946,R11168	RC00589,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
TLS3_k127_8268025_0	1089544.KB912942_gene1439	1.411e-182	580.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4DXI1@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
TLS3_k127_8269970_3	1120948.KB903229_gene5352	4.584e-24	106.0	COG1024@1|root,COG1024@2|Bacteria,2I9DY@201174|Actinobacteria,4EA4D@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
TLS3_k127_8269970_1	1120948.KB903229_gene5353	4.02e-58	209.0	COG1846@1|root,COG1846@2|Bacteria,2HGXY@201174|Actinobacteria,4E4EP@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
TLS3_k127_8269970_0	1120948.KB903229_gene5354	0.0	1068.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,4DZEW@85010|Pseudonocardiales	201174|Actinobacteria	EGP	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1
TLS3_k127_8269970_2	935866.JAER01000013_gene1057	5.847e-26	107.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4DPIQ@85009|Propionibacteriales	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
TLS3_k127_8273874_0	1120948.KB903246_gene3222	0.0	1230.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GM2E@201174|Actinobacteria,4DY3C@85010|Pseudonocardiales	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD2	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
TLS3_k127_8273874_1	1288079.AUKN01000001_gene4442	5.802e-44	175.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD3	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
TLS3_k127_8311773_5	1382306.JNIM01000001_gene1536	1.095e-74	264.0	COG0620@1|root,COG0620@2|Bacteria,2G7J6@200795|Chloroflexi	200795|Chloroflexi	E	Methionine synthase vitamin-B12 independent	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
TLS3_k127_8311773_6	383372.Rcas_2758	3.898e-62	234.0	COG0620@1|root,COG0620@2|Bacteria,2G7J6@200795|Chloroflexi,377RE@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Methionine synthase, vitamin-B12 independent	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
TLS3_k127_8311773_8	684949.ATTJ01000001_gene457	3.654e-46	177.0	COG0483@1|root,COG0483@2|Bacteria,1WIZ7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
TLS3_k127_8311773_2	675635.Psed_2514	3.356e-132	445.0	COG3848@1|root,COG3848@2|Bacteria,2I3FP@201174|Actinobacteria,4E9TT@85010|Pseudonocardiales	201174|Actinobacteria	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
TLS3_k127_8311773_7	1463909.KL585951_gene2349	2.142e-46	181.0	COG4977@1|root,COG4977@2|Bacteria,2I3RG@201174|Actinobacteria	201174|Actinobacteria	K	AraC-binding-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
TLS3_k127_8311773_4	1120948.KB903217_gene1482	6.023e-98	337.0	COG3371@1|root,COG3371@2|Bacteria,2ISXM@201174|Actinobacteria,4ECYP@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
TLS3_k127_8311773_3	479432.Sros_4460	2.576e-131	447.0	COG2234@1|root,COG2234@2|Bacteria,2I9BM@201174|Actinobacteria,4EMQR@85012|Streptosporangiales	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
TLS3_k127_8311773_1	1120948.KB903218_gene2114	3.516e-134	437.0	COG1878@1|root,COG1878@2|Bacteria,2GNFV@201174|Actinobacteria,4DZFT@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
TLS3_k127_8311773_0	675635.Psed_4489	1.329e-180	592.0	COG0028@1|root,COG0028@2|Bacteria,2GKGX@201174|Actinobacteria,4DZZ5@85010|Pseudonocardiales	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
TLS3_k127_8328896_1	1120948.KB903245_gene3425	1.037e-51	196.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria,4DXVI@85010|Pseudonocardiales	201174|Actinobacteria	S	Sterol carrier protein domain	eis	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
TLS3_k127_8328896_0	1120948.KB903245_gene3426	4.437e-200	630.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4DXDS@85010|Pseudonocardiales	201174|Actinobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
TLS3_k127_8334315_0	1120948.KB903243_gene2332	0.0	1113.0	COG2183@1|root,COG2183@2|Bacteria,2GKCI@201174|Actinobacteria,4E0C9@85010|Pseudonocardiales	201174|Actinobacteria	K	accessory protein	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
TLS3_k127_8334315_1	1120948.KB903243_gene2333	2.422e-218	685.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4DXFT@85010|Pseudonocardiales	201174|Actinobacteria	M	amidohydrolase	amiA	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
TLS3_k127_8334315_2	1120948.KB903243_gene2334	4.972e-161	517.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4E080@85010|Pseudonocardiales	201174|Actinobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
TLS3_k127_8371933_4	1120948.KB903218_gene1910	5.476e-25	106.0	COG2453@1|root,COG2453@2|Bacteria,2IFIW@201174|Actinobacteria,4E7QT@85010|Pseudonocardiales	201174|Actinobacteria	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
TLS3_k127_8371933_2	1120948.KB903218_gene1901	5.972e-42	172.0	COG1309@1|root,COG1309@2|Bacteria,2IIZR@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_8371933_1	1380347.JNII01000009_gene2089	1.003e-82	294.0	COG3662@1|root,COG3662@2|Bacteria,2GMUA@201174|Actinobacteria,4ESRM@85013|Frankiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
TLS3_k127_8371933_0	1120948.KB903218_gene1897	1.23e-85	288.0	COG1335@1|root,COG1335@2|Bacteria,2I73B@201174|Actinobacteria,4E47F@85010|Pseudonocardiales	201174|Actinobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
TLS3_k127_8394251_0	1120948.KB903243_gene2375	6.176e-157	502.0	COG1482@1|root,COG1482@2|Bacteria,2I8X4@201174|Actinobacteria,4DZK8@85010|Pseudonocardiales	201174|Actinobacteria	G	mannose-6-phosphate isomerase	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
TLS3_k127_8394251_1	1120948.KB903243_gene2374	1.035e-133	433.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4DXEI@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
TLS3_k127_8394251_3	1120948.KB903217_gene911	7.495e-49	182.0	2DDN7@1|root,2ZIN3@2|Bacteria,2IPRD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8394251_2	1120948.KB903217_gene910	2.544e-88	292.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4DXUJ@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
TLS3_k127_8400863_3	1120948.KB903229_gene4967	2.733e-18	85.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4DY91@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
TLS3_k127_8400863_0	1120948.KB903229_gene4968	1.562e-284	885.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4E0AD@85010|Pseudonocardiales	201174|Actinobacteria	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
TLS3_k127_8400863_2	1120948.KB903229_gene4969	7.294e-42	156.0	COG0718@1|root,COG0718@2|Bacteria,2IRC4@201174|Actinobacteria,4E4G9@85010|Pseudonocardiales	201174|Actinobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
TLS3_k127_8400863_1	1120948.KB903229_gene4970	2.926e-98	356.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4DZAV@85010|Pseudonocardiales	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
TLS3_k127_8403525_2	36809.MAB_1957	3.719e-57	203.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria,2398Y@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the HesB IscA family	iscA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
TLS3_k127_8403525_0	675635.Psed_4556	9.492e-106	370.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,4E07Z@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycerate kinase family	glxK	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
TLS3_k127_8403525_1	1120948.KB903248_gene4333	1.633e-75	277.0	2AN86@1|root,31D67@2|Bacteria,2HWWU@201174|Actinobacteria,4DXR9@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3043)	-	GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	-	-	-	-	-	-	-	-	-	DUF3043
TLS3_k127_8403525_3	1120948.KB903248_gene4334	1.883e-52	203.0	COG2087@1|root,COG2087@2|Bacteria,2GM8Q@201174|Actinobacteria,4E5NE@85010|Pseudonocardiales	201174|Actinobacteria	H	PFAM Cobinamide kinase cobinamide phosphate guanyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU,DBI_PRT
TLS3_k127_8407065_0	1120948.KB903245_gene3712	9.418e-308	957.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4DXBD@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
TLS3_k127_8434114_2	1120948.KB903217_gene1681	8.984e-103	347.0	COG1060@1|root,COG1060@2|Bacteria,2GK83@201174|Actinobacteria,4DX6M@85010|Pseudonocardiales	201174|Actinobacteria	H	Elongator protein 3, MiaB family, Radical SAM	fbiC	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
TLS3_k127_8434114_0	1120948.KB903217_gene1680	4.952e-174	557.0	COG1060@1|root,COG1060@2|Bacteria,2GK83@201174|Actinobacteria,4DX6M@85010|Pseudonocardiales	201174|Actinobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
TLS3_k127_8434114_3	105422.BBPM01000021_gene2803	2.35e-65	237.0	COG1309@1|root,COG1309@2|Bacteria,2I9F9@201174|Actinobacteria,2NJRM@228398|Streptacidiphilus	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_8434114_4	105422.BBPM01000021_gene2804	1.81e-56	201.0	COG0454@1|root,COG0456@2|Bacteria,2GNNG@201174|Actinobacteria,2NJ3S@228398|Streptacidiphilus	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	yjgM	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,MarR_2
TLS3_k127_8434114_6	42256.RradSPS_2858	4.509e-13	76.0	COG4270@1|root,COG4270@2|Bacteria,2GQJP@201174|Actinobacteria	201174|Actinobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
TLS3_k127_8434114_1	1120948.KB903217_gene1662	5.836e-125	414.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,4E0NV@85010|Pseudonocardiales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
TLS3_k127_8434114_5	1120948.KB903217_gene1661	2.434e-33	129.0	COG0538@1|root,COG0538@2|Bacteria,2GM3D@201174|Actinobacteria,4E07K@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
TLS3_k127_8458004_1	1123023.JIAI01000002_gene4571	1.596e-148	495.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4EF7B@85010|Pseudonocardiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE
TLS3_k127_8458004_2	1415166.NONO_c08600	2.414e-137	445.0	COG0564@1|root,COG0564@2|Bacteria,2GJ2Z@201174|Actinobacteria,4FW1J@85025|Nocardiaceae	201174|Actinobacteria	J	Pseudouridine synthase	rluA	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
TLS3_k127_8458004_5	1120948.KB903240_gene4177	2.563e-40	167.0	COG1514@1|root,COG1514@2|Bacteria,2IS3S@201174|Actinobacteria,4E6BP@85010|Pseudonocardiales	201174|Actinobacteria	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
TLS3_k127_8458004_3	1449347.JQLN01000007_gene1135	1.786e-89	312.0	COG2070@1|root,COG2070@2|Bacteria,2GKV4@201174|Actinobacteria,2M2F3@2063|Kitasatospora	201174|Actinobacteria	S	Nitronate monooxygenase	yrpB	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
TLS3_k127_8458004_7	1265310.CCBD010000077_gene5438	4.68e-11	64.0	2EK8X@1|root,33DZ6@2|Bacteria,2GWJW@201174|Actinobacteria,23BX0@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_8458004_4	1120948.KB903240_gene4184	2.544e-49	187.0	COG0494@1|root,COG0494@2|Bacteria,2GKUV@201174|Actinobacteria,4EDNA@85010|Pseudonocardiales	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	GntR,NUDIX
TLS3_k127_8458004_8	326442.PSHAb0200	5.537e-10	70.0	COG1404@1|root,COG3291@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,1MU3S@1224|Proteobacteria,1RSP9@1236|Gammaproteobacteria,2Q10K@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PKD,P_proprotein,Peptidase_S8
TLS3_k127_8458004_0	1120948.KB903240_gene4185	0.0	1038.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,2GM65@201174|Actinobacteria,4E0CI@85010|Pseudonocardiales	201174|Actinobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0047727,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	5.4.99.13,5.4.99.2	ko:K01848,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
TLS3_k127_846049_2	1120948.KB903248_gene4315	2.352e-24	104.0	2EGHN@1|root,33A9R@2|Bacteria,2GSZ1@201174|Actinobacteria,4E7HS@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_846049_1	1120948.KB903248_gene4316	1.532e-173	556.0	COG3688@1|root,COG3688@2|Bacteria,2GR19@201174|Actinobacteria,4DZ65@85010|Pseudonocardiales	201174|Actinobacteria	S	RNA-binding protein containing a PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN_YacP
TLS3_k127_846049_0	1120948.KB903248_gene4317	5.238e-289	896.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,2GMC0@201174|Actinobacteria,4E0J9@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase III, epsilon subunit	dnaQ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
TLS3_k127_8461113_2	1077144.AGFF01000014_gene3032	7.595e-82	275.0	COG0461@1|root,COG0461@2|Bacteria,2GKUQ@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
TLS3_k127_8461113_1	1120948.KB903217_gene1183	2.887e-107	357.0	COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,4DXQX@85010|Pseudonocardiales	201174|Actinobacteria	J	PFAM SpoU rRNA Methylase family	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
TLS3_k127_8461113_0	1120948.KB903217_gene1184	1.277e-116	380.0	COG0586@1|root,COG0586@2|Bacteria,2GKGR@201174|Actinobacteria,4DX3S@85010|Pseudonocardiales	201174|Actinobacteria	S	SNARE associated Golgi protein	yqjA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
TLS3_k127_8483301_2	1123024.AUII01000002_gene978	7.021e-111	383.0	COG1807@1|root,COG1807@2|Bacteria,2GKH9@201174|Actinobacteria,4DXMQ@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Mycobacterial cell wall arabinan synthesis protein	-	-	-	ko:K11385,ko:K11386,ko:K11387	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Arabino_trans_C,Arabinose_trans
TLS3_k127_8483301_0	1120948.KB903219_gene744	1.543e-250	808.0	COG0277@1|root,COG0277@2|Bacteria,2HJEG@201174|Actinobacteria,4E0HR@85010|Pseudonocardiales	201174|Actinobacteria	C	FAD binding domain	-	-	1.1.98.3	ko:K16653	-	-	-	-	ko00000,ko01000	-	-	-	ALO,FAD_binding_4
TLS3_k127_8483301_1	1120948.KB903219_gene743	1.286e-135	435.0	COG1028@1|root,COG1028@2|Bacteria,2I2RJ@201174|Actinobacteria,4E134@85010|Pseudonocardiales	201174|Actinobacteria	IQ	PFAM short chain dehydrogenase	dprE2	GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576	1.1.1.333	ko:K16652	-	-	-	-	ko00000,ko01000	-	-	iNJ661.Rv3791	adh_short
TLS3_k127_8483301_3	1120948.KB903220_gene118	2.12e-90	304.0	COG0235@1|root,COG0235@2|Bacteria,2GNI6@201174|Actinobacteria,4E429@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Class II Aldolase and Adducin N-terminal domain	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
TLS3_k127_8483301_4	66377.JOBH01000015_gene4095	6.783e-61	216.0	COG0406@1|root,COG0406@2|Bacteria,2I9GN@201174|Actinobacteria	201174|Actinobacteria	G	phosphoglycerate mutase	-	-	3.1.3.85,5.4.2.12	ko:K15634,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
TLS3_k127_850334_1	1120948.KB903217_gene1507	1.31e-138	470.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4DZJ7@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	1.14.15.14	ko:K20497	-	-	-	-	ko00000,ko00199,ko01000	-	-	-	p450
TLS3_k127_850334_0	1120948.KB903243_gene2488	5.417e-149	488.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria,4E0QR@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C
TLS3_k127_850334_4	1120948.KB903217_gene1506	1.93e-20	93.0	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
TLS3_k127_850334_2	2074.JNYD01000017_gene4288	8.548e-92	317.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria,4E086@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase carnithine racemase	echA21	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
TLS3_k127_850334_3	1122611.KB903940_gene2058	3.159e-43	164.0	COG0589@1|root,COG0589@2|Bacteria,2ICPM@201174|Actinobacteria	201174|Actinobacteria	T	universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_8517320_0	1120948.KB903217_gene879	0.0	1047.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4E0NF@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
TLS3_k127_8517320_4	675635.Psed_3612	1.222e-74	264.0	COG0537@1|root,COG0537@2|Bacteria,2GJT5@201174|Actinobacteria,4DYSQ@85010|Pseudonocardiales	201174|Actinobacteria	FG	HIT family hydrolase, diadenosine tetraphosphate hydrolase	-	GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
TLS3_k127_8517320_3	1120948.KB903217_gene881	6.522e-79	280.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4E1BR@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.11,2.7.8.5	ko:K00995,ko:K00999	ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070	-	R01801,R01802	RC00002,RC00017,RC00078,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
TLS3_k127_8517320_1	1120948.KB903217_gene882	4.83e-124	418.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria,4E0NM@85010|Pseudonocardiales	201174|Actinobacteria	M	lipid A biosynthesis acyltransferase	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
TLS3_k127_8517320_2	1120948.KB903217_gene893	6.004e-92	312.0	COG1940@1|root,COG1940@2|Bacteria,2GJ2S@201174|Actinobacteria,4E1VA@85010|Pseudonocardiales	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
TLS3_k127_8519852_1	1120948.KB903240_gene4135	6.436e-117	394.0	COG0119@1|root,COG0119@2|Bacteria,2GJBI@201174|Actinobacteria,4DXVR@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds	mhpE	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DmpG_comm,HMGL-like
TLS3_k127_8519852_0	1120948.KB903240_gene4134	4.016e-147	471.0	COG4569@1|root,COG4569@2|Bacteria,2GKBZ@201174|Actinobacteria,4DY19@85010|Pseudonocardiales	201174|Actinobacteria	Q	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds	mhpF	-	1.2.1.10	ko:K04073	ko00360,ko00362,ko00620,ko00621,ko00622,ko00650,ko01100,ko01120,ko01220,map00360,map00362,map00620,map00621,map00622,map00650,map01100,map01120,map01220	M00545,M00569	R00228,R01172	RC00004,RC00184,RC01195	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	AcetDehyd-dimer,Semialdhyde_dh
TLS3_k127_8537327_1	1054860.KB913030_gene5473	3.108e-74	265.0	COG1020@1|root,COG1020@2|Bacteria	2|Bacteria	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_11,Methyltransf_12,Methyltransf_25,PP-binding
TLS3_k127_8537327_0	455632.SGR_448	0.0	1437.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,417CI@629295|Streptomyces griseus group	201174|Actinobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
TLS3_k127_8540759_7	443218.AS9A_3076	2.26e-27	117.0	COG1018@1|root,COG3239@1|root,COG1018@2|Bacteria,COG3239@2|Bacteria,2GKGS@201174|Actinobacteria,235X3@1762|Mycobacteriaceae	201174|Actinobacteria	C	Oxidoreductase FAD-binding domain	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,FA_desaturase,Fer2,NAD_binding_1
TLS3_k127_8540759_6	1120948.KB903243_gene2505	9.168e-51	182.0	COG1359@1|root,COG1359@2|Bacteria,2IQ6Y@201174|Actinobacteria,4E4NZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
TLS3_k127_8540759_1	1068980.ARVW01000001_gene3421	1.155e-166	538.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DX6S@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08167	-	M00713,M00714	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3	-	-	MFS_1
TLS3_k127_8540759_5	1120948.KB903243_gene2501	8.593e-53	193.0	COG1309@1|root,COG1309@2|Bacteria,2IQNP@201174|Actinobacteria,4E5K8@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_8540759_3	2074.JNYD01000025_gene605	2.502e-59	213.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	ftrB	-	-	ko:K01420,ko:K13642,ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
TLS3_k127_8540759_0	2074.JNYD01000025_gene599	9.263e-176	561.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4E87E@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
TLS3_k127_8540759_8	405948.SACE_2903	8.777e-24	108.0	COG0589@1|root,COG0589@2|Bacteria,2GT7T@201174|Actinobacteria,4E7WR@85010|Pseudonocardiales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
TLS3_k127_8540759_4	1120948.KB903225_gene5546	1.782e-54	208.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria,4E4HH@85010|Pseudonocardiales	201174|Actinobacteria	M	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
TLS3_k127_8540759_2	1120948.KB903225_gene5544	3.211e-76	279.0	COG3011@1|root,COG3011@2|Bacteria,2GN4W@201174|Actinobacteria	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
TLS3_k127_8554348_1	1120948.KB903248_gene4223	7.89e-155	500.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4E18N@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	GO:0008150,GO:0040007	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1595	FAD_binding_2,Succ_DH_flav_C
TLS3_k127_8554348_4	1120948.KB903248_gene4222	8.045e-137	449.0	COG0157@1|root,COG0157@2|Bacteria,2I2IP@201174|Actinobacteria,4DX6B@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the NadC ModD family	nadC	GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0030312,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
TLS3_k127_8554348_3	1120948.KB903248_gene4220	9.541e-144	468.0	COG0665@1|root,COG0665@2|Bacteria,2HNJI@201174|Actinobacteria,4E26Y@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
TLS3_k127_8554348_16	1120948.KB903248_gene4219	5.224e-14	76.0	COG5297@1|root,COG5297@2|Bacteria,2HDPZ@201174|Actinobacteria,4E329@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 12	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_12,RicinB_lectin_2,Ricin_B_lectin
TLS3_k127_8554348_8	1120948.KB903248_gene4218	5.638e-99	329.0	COG5297@1|root,COG5297@2|Bacteria,2HDPZ@201174|Actinobacteria,4E329@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 12	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_12,RicinB_lectin_2,Ricin_B_lectin
TLS3_k127_8554348_0	42256.RradSPS_0709	2.295e-155	508.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4CRFF@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_8554348_13	42256.RradSPS_0708	2.363e-45	174.0	COG1309@1|root,COG1309@2|Bacteria,2IKQ8@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_8554348_11	1120948.KB903248_gene4217	7.777e-48	191.0	COG1188@1|root,COG1188@2|Bacteria,2IQ6F@201174|Actinobacteria,4E4HE@85010|Pseudonocardiales	201174|Actinobacteria	J	S4 RNA-binding domain	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
TLS3_k127_8554348_2	1120948.KB903218_gene2262	7.245e-150	486.0	COG2141@1|root,COG2141@2|Bacteria,2GMMJ@201174|Actinobacteria,4E2MJ@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
TLS3_k127_8554348_10	1120948.KB903218_gene2261	7.327e-49	190.0	COG3467@1|root,COG3467@2|Bacteria,2IQIK@201174|Actinobacteria,4E5TC@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
TLS3_k127_8554348_6	1123023.JIAI01000032_gene4165	7.966e-114	380.0	COG2239@1|root,COG2239@2|Bacteria,2I9TV@201174|Actinobacteria,4EEP1@85010|Pseudonocardiales	201174|Actinobacteria	P	Divalent cation transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE
TLS3_k127_8554348_15	479432.Sros_4835	2.898e-26	114.0	COG3467@1|root,COG3467@2|Bacteria,2GQIA@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
TLS3_k127_8554348_5	101510.RHA1_ro02711	3.68e-117	402.0	COG1073@1|root,COG1073@2|Bacteria,2GNB6@201174|Actinobacteria,4FXHV@85025|Nocardiaceae	201174|Actinobacteria	S	Protein involved in hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	AXE1,Abhydrolase_1,Abhydrolase_6,Peptidase_S15
TLS3_k127_8554348_12	1194165.CAJF01000001_gene1845	1.041e-46	181.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix HxlR type	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
TLS3_k127_8554348_9	749414.SBI_00456	4.244e-66	235.0	COG2227@1|root,COG2227@2|Bacteria,2ICS8@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
TLS3_k127_8554348_17	1121946.AUAX01000008_gene7160	3.885e-10	64.0	COG2267@1|root,COG2267@2|Bacteria,2GJUE@201174|Actinobacteria,4DMC4@85008|Micromonosporales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	ko:K21209	ko01059,map01059	-	-	-	ko00000,ko00001	-	-	-	Abhydrolase_6
TLS3_k127_8554348_19	1157640.AQWO01000010_gene2778	0.0008741	42.0	COG1846@1|root,COG1846@2|Bacteria,2ISSY@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
TLS3_k127_8554348_7	1120948.KB903248_gene4214	1.233e-108	359.0	COG0491@1|root,COG0491@2|Bacteria,2GKJA@201174|Actinobacteria,4DY0X@85010|Pseudonocardiales	201174|Actinobacteria	S	Zn-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
TLS3_k127_8554348_14	882083.SacmaDRAFT_4968	3.389e-30	123.0	2DMA2@1|root,32B92@2|Bacteria,2IMA7@201174|Actinobacteria,4EFEV@85010|Pseudonocardiales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
TLS3_k127_864317_0	1120948.KB903247_gene4497	1.882e-152	497.0	COG4398@1|root,COG4398@2|Bacteria,2I3VH@201174|Actinobacteria,4E1JP@85010|Pseudonocardiales	201174|Actinobacteria	S	FIST N domain	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
TLS3_k127_864317_3	1120948.KB903247_gene4498	2.166e-57	202.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4E3PI@85010|Pseudonocardiales	201174|Actinobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
TLS3_k127_864317_2	1120948.KB903247_gene4499	1.477e-66	232.0	COG0406@1|root,COG0406@2|Bacteria,2GJYU@201174|Actinobacteria,4E1T2@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the phosphoglycerate mutase family	gpmB	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237	3.1.3.85,5.4.2.11	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
TLS3_k127_864317_1	1123024.AUII01000008_gene1831	7.677e-67	248.0	COG2755@1|root,COG2755@2|Bacteria,2GR6W@201174|Actinobacteria,4DZQ1@85010|Pseudonocardiales	201174|Actinobacteria	E	O-octanoyltransferase activity	octT	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008374,GO:0009987,GO:0016020,GO:0016043,GO:0016414,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0022607,GO:0040007,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051262,GO:0065003,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS3_k127_870322_2	1120948.KB903217_gene1623	3.455e-144	482.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,4DZ1S@85010|Pseudonocardiales	201174|Actinobacteria	S	TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
TLS3_k127_870322_0	1123023.JIAI01000003_gene2788	9.316e-285	893.0	COG0804@1|root,COG0804@2|Bacteria,2GM7X@201174|Actinobacteria,4E07M@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
TLS3_k127_870322_6	1123023.JIAI01000003_gene2787	2.246e-71	248.0	COG0831@1|root,COG0832@1|root,COG0831@2|Bacteria,COG0832@2|Bacteria,2IKNA@201174|Actinobacteria,4E4YV@85010|Pseudonocardiales	201174|Actinobacteria	E	Urease beta subunit	-	-	3.5.1.5	ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
TLS3_k127_870322_3	446462.Amir_3972	5.725e-120	401.0	COG0654@1|root,COG0654@2|Bacteria,2GXK6@201174|Actinobacteria,4DZD1@85010|Pseudonocardiales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
TLS3_k127_870322_5	1068978.AMETH_2727	8.78e-77	286.0	COG1414@1|root,COG1414@2|Bacteria,2GP0G@201174|Actinobacteria,4E9YK@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
TLS3_k127_870322_4	1068978.AMETH_2728	2.478e-96	336.0	COG0531@1|root,COG0531@2|Bacteria,2ID3V@201174|Actinobacteria,4EAAP@85010|Pseudonocardiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
TLS3_k127_870322_1	675635.Psed_3748	4.598e-145	494.0	COG0531@1|root,COG0531@2|Bacteria,2GJ1D@201174|Actinobacteria,4DXME@85010|Pseudonocardiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
TLS3_k127_876985_4	1120948.KB903218_gene1910	4.474e-18	85.0	COG2453@1|root,COG2453@2|Bacteria,2IFIW@201174|Actinobacteria,4E7QT@85010|Pseudonocardiales	201174|Actinobacteria	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
TLS3_k127_876985_1	1120948.KB903246_gene3247	2.064e-55	197.0	COG2146@1|root,COG2146@2|Bacteria,2IFRC@201174|Actinobacteria,4E71A@85010|Pseudonocardiales	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
TLS3_k127_876985_3	1120948.KB903246_gene3246	6.349e-28	116.0	29J49@1|root,3061Q@2|Bacteria,2HS8F@201174|Actinobacteria,4ECVS@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_876985_0	1120948.KB903246_gene3245	7.047e-235	732.0	COG2159@1|root,COG2159@2|Bacteria,2GNF3@201174|Actinobacteria,4E1ZJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
TLS3_k127_876985_2	1283299.AUKG01000005_gene100	1.148e-39	157.0	COG2375@1|root,COG2375@2|Bacteria,2GN5R@201174|Actinobacteria,4CPJS@84995|Rubrobacteria	84995|Rubrobacteria	P	Siderophore-interacting protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_9,SIP
TLS3_k127_877414_3	1120948.KB903217_gene1209	6.155e-07	51.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4DXHH@85010|Pseudonocardiales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
TLS3_k127_877414_0	1120948.KB903217_gene1210	1.318e-69	246.0	COG2755@1|root,COG2755@2|Bacteria,2HP4Y@201174|Actinobacteria,4E7QP@85010|Pseudonocardiales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
TLS3_k127_877414_1	685727.REQ_08390	5.687e-43	163.0	COG3255@1|root,COG3255@2|Bacteria,2IQBF@201174|Actinobacteria,4G262@85025|Nocardiaceae	201174|Actinobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
TLS3_k127_877414_2	1120948.KB903217_gene1212	4.154e-37	141.0	COG2890@1|root,COG2890@2|Bacteria,2GITA@201174|Actinobacteria,4E0ST@85010|Pseudonocardiales	201174|Actinobacteria	J	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
TLS3_k127_883266_0	1120948.KB903243_gene2324	0.0	1013.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4DZ8S@85010|Pseudonocardiales	201174|Actinobacteria	I	Biotin carboxylase	accBC	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3285	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
TLS3_k127_883266_3	1120948.KB903243_gene2322	5.03e-73	254.0	COG0424@1|root,COG0424@2|Bacteria,2GNI0@201174|Actinobacteria,4E2ME@85010|Pseudonocardiales	201174|Actinobacteria	D	Maf-like protein	maf	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf,NUDIX
TLS3_k127_883266_1	2074.JNYD01000055_gene2332	3.641e-129	420.0	COG4312@1|root,COG4312@2|Bacteria,2GIVC@201174|Actinobacteria,4E2Q4@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
TLS3_k127_883266_4	1151119.KB895497_gene3304	6.127e-44	164.0	COG4319@1|root,COG4319@2|Bacteria,2H1H4@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
TLS3_k127_883266_2	208444.JNYY01000001_gene4757	1.878e-81	276.0	COG1309@1|root,COG1309@2|Bacteria,2IKG3@201174|Actinobacteria,4EEZ7@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_883362_0	1120948.KB903228_gene4813	1.737e-137	453.0	COG0859@1|root,COG0859@2|Bacteria,2GSTW@201174|Actinobacteria,4DYGA@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,Hydrolase_like
TLS3_k127_883362_1	1120948.KB903228_gene4814	3.193e-59	221.0	COG0241@1|root,COG0241@2|Bacteria,2GK77@201174|Actinobacteria,4E3VS@85010|Pseudonocardiales	201174|Actinobacteria	E	HAD-hyrolase-like	gmhB	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Hydrolase_like
TLS3_k127_883362_2	1120948.KB903228_gene4815	1.186e-38	162.0	COG2172@1|root,COG2172@2|Bacteria,2IFG9@201174|Actinobacteria,4E6WZ@85010|Pseudonocardiales	201174|Actinobacteria	T	anti-sigma regulatory factor	rsbW	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
TLS3_k127_884134_1	1120948.KB903244_gene2795	3.092e-46	168.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4DYTC@85010|Pseudonocardiales	201174|Actinobacteria	E	NADH NADPH, small subunit	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3858c	Fer4_20,Pyr_redox_2
TLS3_k127_884134_2	1120948.KB903244_gene2794	1.258e-19	96.0	2BEMC@1|root,328CT@2|Bacteria,2HE5B@201174|Actinobacteria,4EDEY@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_884134_0	1120948.KB903244_gene2793	1.046e-74	258.0	COG0500@1|root,COG2226@2|Bacteria,2GJAI@201174|Actinobacteria,4EBU5@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
TLS3_k127_885058_3	330084.JNYZ01000024_gene2400	1.943e-55	195.0	COG0393@1|root,COG0393@2|Bacteria,2IHTU@201174|Actinobacteria,4E69Y@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
TLS3_k127_885058_0	1120948.KB903217_gene1343	3.72e-265	828.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DXDJ@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
TLS3_k127_885058_1	749414.SBI_00098	4.856e-157	508.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
TLS3_k127_885058_2	1120948.KB903217_gene1342	9.535e-80	267.0	COG0266@1|root,COG0266@2|Bacteria,2H39J@201174|Actinobacteria,4DZYU@85010|Pseudonocardiales	201174|Actinobacteria	L	Formamidopyrimidine-DNA glycosylase N-terminal domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
TLS3_k127_886949_0	1120948.KB903248_gene4192	7.76e-244	765.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4DZ5Y@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
TLS3_k127_886949_1	1120948.KB903248_gene4193	2.247e-108	356.0	COG2094@1|root,COG2094@2|Bacteria,2GNW1@201174|Actinobacteria,4DZG7@85010|Pseudonocardiales	201174|Actinobacteria	L	Belongs to the DNA glycosylase MPG family	mpg	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
TLS3_k127_886949_3	1123023.JIAI01000011_gene8974	9.782e-72	262.0	COG0741@1|root,COG0741@2|Bacteria,2IBCH@201174|Actinobacteria	201174|Actinobacteria	M	Transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1460,NLPC_P60,SLT,SLT_2
TLS3_k127_886949_2	1120948.KB903248_gene4194	1.736e-90	299.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4DZSC@85010|Pseudonocardiales	201174|Actinobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
TLS3_k127_889609_2	675635.Psed_5343	5.609e-48	197.0	COG1983@1|root,COG1983@2|Bacteria,2GIVS@201174|Actinobacteria,4E1BF@85010|Pseudonocardiales	201174|Actinobacteria	KT	PFAM PspC domain	pspC	-	-	-	-	-	-	-	-	-	-	-	DUF2154,PspC
TLS3_k127_889609_0	1120948.KB903217_gene1626	3.787e-143	469.0	COG4585@1|root,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4DXQC@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	tcsS3	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,PspC
TLS3_k127_889609_1	1120948.KB903217_gene1627	2.62e-106	370.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4DZWV@85010|Pseudonocardiales	201174|Actinobacteria	T	Response regulator receiver	tcsR3	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
TLS3_k127_889609_3	1120948.KB903217_gene1637	9.965e-07	56.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4DX5D@85010|Pseudonocardiales	201174|Actinobacteria	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
TLS3_k127_899207_8	321846.PS417_16120	0.0003446	50.0	COG3710@1|root,COG3903@1|root,COG3710@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,NACHT,NB-ARC,Trans_reg_C
TLS3_k127_899207_4	512565.AMIS_18580	4.163e-57	211.0	COG3903@1|root,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
TLS3_k127_899207_3	1169161.KB897733_gene568	3.729e-62	224.0	COG1309@1|root,COG1309@2|Bacteria,2HMJ5@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
TLS3_k127_899207_1	67267.JNXT01000014_gene269	4.155e-82	292.0	COG2041@1|root,COG2041@2|Bacteria	2|Bacteria	V	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
TLS3_k127_899207_7	1120948.KB903225_gene5550	0.000255	47.0	28Z7S@1|root,2ZKZX@2|Bacteria,2GX1K@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
TLS3_k127_899207_2	1120948.KB903229_gene5393	1.232e-81	280.0	COG0586@1|root,COG0586@2|Bacteria,2IP88@201174|Actinobacteria	201174|Actinobacteria	S	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
TLS3_k127_899207_0	446468.Ndas_2172	5.295e-132	435.0	COG2271@1|root,COG2271@2|Bacteria,2HB3P@201174|Actinobacteria,4EP3Q@85012|Streptosporangiales	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
TLS3_k127_899207_6	1236902.ANAS01000004_gene3627	6.293e-11	64.0	2A30V@1|root,30RFJ@2|Bacteria,2H1ZY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_907582_3	1120948.KB903245_gene3673	3.297e-167	527.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4E06T@85010|Pseudonocardiales	201174|Actinobacteria	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
TLS3_k127_907582_0	1120948.KB903245_gene3672	7.44e-241	751.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4DYFS@85010|Pseudonocardiales	201174|Actinobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
TLS3_k127_907582_2	2074.JNYD01000008_gene1067	4.213e-184	606.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4E08Y@85010|Pseudonocardiales	201174|Actinobacteria	E	homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
TLS3_k127_907582_1	1120948.KB903245_gene3670	2.434e-188	594.0	COG0498@1|root,COG0498@2|Bacteria,2GJ5F@201174|Actinobacteria,4DYEK@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
TLS3_k127_907582_4	1120948.KB903245_gene3669	8.053e-113	393.0	COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,4DZTR@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
TLS3_k127_907582_5	1089544.KB912942_gene20	7.95e-12	74.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,4DX4E@85010|Pseudonocardiales	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
TLS3_k127_913873_0	1120948.KB903244_gene2878	2.013e-108	353.0	28J4D@1|root,2Z90C@2|Bacteria,2GJYC@201174|Actinobacteria,4E2HQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3710)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3710
TLS3_k127_913873_3	1120948.KB903244_gene2877	1.228e-53	203.0	COG1200@1|root,COG1200@2|Bacteria,2IHRX@201174|Actinobacteria,4E4G1@85010|Pseudonocardiales	201174|Actinobacteria	KL	Nucleic acid binding, OB-fold, tRNA	-	-	-	-	-	-	-	-	-	-	-	-	-
TLS3_k127_913873_2	1120948.KB903244_gene2876	9.337e-95	319.0	2AVV0@1|root,31MNQ@2|Bacteria,2GJKP@201174|Actinobacteria,4E1F2@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3159
TLS3_k127_913873_1	1120948.KB903244_gene2868	5.763e-98	322.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4DY80@85010|Pseudonocardiales	201174|Actinobacteria	P	overlaps another CDS with the same product name	ceoC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
TLS3_k127_920342_2	1120948.KB903245_gene3492	2.108e-156	498.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,4DY1U@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0008150,GO:0040007	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2977c	AIRS,AIRS_C
TLS3_k127_920342_1	1120948.KB903245_gene3491	4.921e-247	775.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4DYFJ@85010|Pseudonocardiales	201174|Actinobacteria	C	Fe-S oxidoreductase	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
TLS3_k127_920342_3	1120948.KB903245_gene3490	1.841e-123	413.0	COG0277@1|root,COG0277@2|Bacteria,2H3K3@201174|Actinobacteria,4E18A@85010|Pseudonocardiales	201174|Actinobacteria	C	overlaps another CDS with the same product name	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
TLS3_k127_920342_0	1120948.KB903245_gene3489	2.736e-257	809.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4E05Y@85010|Pseudonocardiales	201174|Actinobacteria	C	Glycolate oxidase subunit GlcD	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
TLS3_k127_920342_6	1120948.KB903245_gene3488	1.065e-60	225.0	COG0546@1|root,COG0546@2|Bacteria,2IKNN@201174|Actinobacteria,4E2RT@85010|Pseudonocardiales	201174|Actinobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
TLS3_k127_920342_5	1120950.KB892774_gene1232	7.251e-75	261.0	COG1414@1|root,COG1414@2|Bacteria,2GJUA@201174|Actinobacteria,4DNQB@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	iclR	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
TLS3_k127_920342_4	1120948.KB903245_gene3485	2.808e-120	389.0	COG0692@1|root,COG0692@2|Bacteria,2GJ9Z@201174|Actinobacteria,4DYR2@85010|Pseudonocardiales	201174|Actinobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
TLS3_k127_924015_1	208444.JNYY01000025_gene5959	8.059e-09	60.0	COG0443@1|root,COG0443@2|Bacteria,2GNTE@201174|Actinobacteria,4E043@85010|Pseudonocardiales	201174|Actinobacteria	O	Hsp70 protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
TLS3_k127_924015_0	749927.AMED_5170	1.28e-163	529.0	COG0699@1|root,COG0699@2|Bacteria,2GK6T@201174|Actinobacteria,4DYHH@85010|Pseudonocardiales	201174|Actinobacteria	T	GTPases (dynamin-related)	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N,MMR_HSR1
TLS3_k127_986927_1	1123024.AUII01000059_gene540	5.846e-73	266.0	COG2208@1|root,COG2208@2|Bacteria,2GNG4@201174|Actinobacteria,4E0KW@85010|Pseudonocardiales	201174|Actinobacteria	KT	PFAM Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
TLS3_k127_986927_0	1206731.BAGB01000041_gene8339	1.747e-90	308.0	COG1878@1|root,COG1878@2|Bacteria,2GJ59@201174|Actinobacteria,4FWUB@85025|Nocardiaceae	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
## 4371 queries scanned
## Total time (seconds): 66.01251149177551
## Rate: 66.21 q/s