## Tue Dec 16 10:34:28 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/WH1_bin.27.fa -m mmseqs --itype genome -o WH1_bin.27 --output_dir /data/result/bins/wyx/egg/WH1_bin.27 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
WH1_k127_10004652_1	7245.FBpp0260894	3.71e-31	125.0	2D82N@1|root,2T8G1@2759|Eukaryota,3930P@33154|Opisthokonta,3C8AX@33208|Metazoa,3DPBM@33213|Bilateria,425JT@6656|Arthropoda,3SV54@50557|Insecta,4587U@7147|Diptera,45Z7T@7214|Drosophilidae	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_10004652_0	926569.ANT_19610	1.631e-47	179.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
WH1_k127_10004652_2	867845.KI911784_gene2223	1.785e-16	82.0	COG0179@1|root,COG0179@2|Bacteria,2GAI8@200795|Chloroflexi,376AT@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
WH1_k127_10016729_3	485913.Krac_11193	1.601e-18	93.0	COG0460@1|root,COG0460@2|Bacteria,2G6PU@200795|Chloroflexi	200795|Chloroflexi	E	homoserine dehydrogenase	metM	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
WH1_k127_10016729_0	926569.ANT_27550	8.323e-82	282.0	COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi	200795|Chloroflexi	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
WH1_k127_10016729_2	926569.ANT_04570	5.519e-48	178.0	298YA@1|root,2ZW25@2|Bacteria,2G6UQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
WH1_k127_10016729_1	1128421.JAGA01000003_gene3534	2.864e-64	226.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.3,3.1.3.73,5.4.2.12	ko:K02226,ko:K15634,ko:K22305	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00122	R00582,R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
WH1_k127_10028508_0	28072.Nos7524_1360	5.495e-133	441.0	COG0764@1|root,COG3321@1|root,COG0764@2|Bacteria,COG3321@2|Bacteria,1G37Y@1117|Cyanobacteria,1HKND@1161|Nostocales	1117|Cyanobacteria	Q	Belongs to the beta-ketoacyl-ACP synthases family	-	-	-	-	-	-	-	-	-	-	-	-	FabA,Ketoacyl-synt_C,ketoacyl-synt
WH1_k127_10028508_1	28072.Nos7524_1360	6.26e-50	197.0	COG0764@1|root,COG3321@1|root,COG0764@2|Bacteria,COG3321@2|Bacteria,1G37Y@1117|Cyanobacteria,1HKND@1161|Nostocales	1117|Cyanobacteria	Q	Belongs to the beta-ketoacyl-ACP synthases family	-	-	-	-	-	-	-	-	-	-	-	-	FabA,Ketoacyl-synt_C,ketoacyl-synt
WH1_k127_10029698_0	671143.DAMO_2736	3.964e-92	314.0	2DBSW@1|root,2ZAU8@2|Bacteria	2|Bacteria	S	PFAM CRISPR-associated protein, GSU0054	-	-	-	ko:K19132	-	-	-	-	ko00000,ko02048	-	-	-	-
WH1_k127_10029698_1	671143.DAMO_2737	7.679e-79	269.0	28IJY@1|root,2Z8KS@2|Bacteria	2|Bacteria	S	CRISPR-associated protein GSU0053 (Cas_GSU0053)	-	-	-	ko:K19131	-	-	-	-	ko00000,ko02048	-	-	-	Cas_GSU0053
WH1_k127_10041273_0	215803.DB30_8096	1.063e-73	260.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,42NWG@68525|delta/epsilon subdivisions,2WKEU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
WH1_k127_10041273_2	383372.Rcas_2986	2.577e-45	173.0	COG1011@1|root,COG1011@2|Bacteria,2G979@200795|Chloroflexi,377GE@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WH1_k127_10041273_1	1487953.JMKF01000015_gene6221	2.098e-73	253.0	COG1940@1|root,COG1940@2|Bacteria,1G4PJ@1117|Cyanobacteria,1H8TR@1150|Oscillatoriales	1117|Cyanobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
WH1_k127_10055424_0	926550.CLDAP_35810	2.524e-65	241.0	COG3359@1|root,COG3359@2|Bacteria	2|Bacteria	L	RNase_H superfamily	yprB	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
WH1_k127_10057009_1	926550.CLDAP_01060	7.849e-79	268.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi	200795|Chloroflexi	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WH1_k127_10057009_0	926569.ANT_12000	1.806e-103	351.0	COG0006@1|root,COG0006@2|Bacteria,2G5J6@200795|Chloroflexi	200795|Chloroflexi	C	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WH1_k127_1006691_1	1128421.JAGA01000003_gene3354	3.608e-32	132.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	remC	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WH1_k127_1006691_2	926550.CLDAP_02020	2.892e-29	137.0	COG1520@1|root,COG1520@2|Bacteria,2G93W@200795|Chloroflexi	200795|Chloroflexi	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
WH1_k127_1006691_0	765420.OSCT_0859	2.935e-116	409.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
WH1_k127_10075214_1	926569.ANT_30270	5.703e-87	293.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,2G75J@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
WH1_k127_10075214_0	926569.ANT_01740	2.088e-156	512.0	COG5360@1|root,COG5360@2|Bacteria	2|Bacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
WH1_k127_10079859_2	926569.ANT_14720	8.56e-11	62.0	COG1109@1|root,COG1109@2|Bacteria,2G5Y4@200795|Chloroflexi	200795|Chloroflexi	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WH1_k127_10079859_1	644966.Tmar_0084	7.543e-69	242.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,3WD1R@538999|Clostridiales incertae sedis	186801|Clostridia	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
WH1_k127_10079859_0	926569.ANT_14700	1.032e-81	281.0	COG0142@1|root,COG0142@2|Bacteria,2G6IZ@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
WH1_k127_10095099_0	926569.ANT_13730	9.085e-80	273.0	COG0217@1|root,COG0217@2|Bacteria,2G6AI@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulatory protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
WH1_k127_10095099_1	926569.ANT_13740	1.981e-58	207.0	COG0817@1|root,COG0817@2|Bacteria,2G6MA@200795|Chloroflexi	200795|Chloroflexi	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
WH1_k127_10095099_2	926550.CLDAP_12580	1.704e-48	179.0	COG0632@1|root,COG0632@2|Bacteria,2G6V7@200795|Chloroflexi	200795|Chloroflexi	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
WH1_k127_10095099_3	926569.ANT_16300	3.507e-25	119.0	COG0345@1|root,COG0345@2|Bacteria,2G5QD@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
WH1_k127_10106839_2	644282.Deba_2981	1.978e-92	319.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
WH1_k127_10106839_0	525909.Afer_0719	1.126e-124	418.0	COG0320@1|root,COG0321@1|root,COG0320@2|Bacteria,COG0321@2|Bacteria,2GKD4@201174|Actinobacteria,4CMR4@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,LIAS_N,Radical_SAM
WH1_k127_10106839_1	1089553.Tph_c19590	1.233e-93	324.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD_binding_4
WH1_k127_10122436_0	1173028.ANKO01000008_gene2104	1.624e-184	617.0	COG0642@1|root,COG3829@1|root,COG4251@1|root,COG0642@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1GHC4@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS_2,PAS_3,PAS_9,PHY,Response_reg
WH1_k127_10136635_0	765420.OSCT_2114	1.342e-79	305.0	COG2931@1|root,COG2931@2|Bacteria,2GBI9@200795|Chloroflexi,377IY@32061|Chloroflexia	32061|Chloroflexia	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
WH1_k127_10136635_2	671143.DAMO_1627	1.227e-26	130.0	COG0823@1|root,COG1572@1|root,COG0823@2|Bacteria,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
WH1_k127_10136635_3	1227739.Hsw_1282	2.424e-17	99.0	COG1864@1|root,COG2353@1|root,COG2374@1|root,COG3391@1|root,COG3405@1|root,COG1864@2|Bacteria,COG2353@2|Bacteria,COG2374@2|Bacteria,COG3391@2|Bacteria,COG3405@2|Bacteria,4NURG@976|Bacteroidetes,47P25@768503|Cytophagia	976|Bacteroidetes	G	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
WH1_k127_10136635_1	1157640.AQWO01000007_gene3565	8.005e-75	289.0	COG3391@1|root,COG3391@2|Bacteria,2H4SV@201174|Actinobacteria	201174|Actinobacteria	MU	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5
WH1_k127_10142833_1	479434.Sthe_1850	3.107e-53	202.0	COG0419@1|root,COG0419@2|Bacteria,2G682@200795|Chloroflexi,27XPG@189775|Thermomicrobia	189775|Thermomicrobia	L	Rad50 zinc hook motif	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SbcCD_C
WH1_k127_10142833_0	324602.Caur_1629	2.896e-57	211.0	COG0420@1|root,COG0420@2|Bacteria,2G60M@200795|Chloroflexi,3757S@32061|Chloroflexia	32061|Chloroflexia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
WH1_k127_1014873_2	1121396.KB893086_gene307	6.194e-23	101.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42M6J@68525|delta/epsilon subdivisions,2WJZQ@28221|Deltaproteobacteria,2MJ1A@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM 3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WH1_k127_1014873_0	1118054.CAGW01000024_gene348	1.534e-78	271.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HB73@91061|Bacilli,271SW@186822|Paenibacillaceae	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	M00087	R03026,R04170,R04738,R04740,R04744,R04746	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WH1_k127_1014873_1	1002809.SSIL_3404	4.494e-64	231.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,26DW2@186818|Planococcaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, middle domain	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH1_k127_10156661_4	1122963.AUHB01000008_gene3413	1.045e-09	67.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,36XEB@31993|Methylocystaceae	28211|Alphaproteobacteria	T	Domain of unknown function (DUF4118)	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
WH1_k127_10156661_2	926550.CLDAP_11920	6.332e-65	253.0	COG2132@1|root,COG5617@1|root,COG2132@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K07233,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3,PTPS_related
WH1_k127_10156661_0	573413.Spirs_3288	1.118e-109	367.0	COG0075@1|root,COG0075@2|Bacteria,2J84T@203691|Spirochaetes	203691|Spirochaetes	E	PFAM aminotransferase class V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
WH1_k127_10156661_3	220668.lp_2806	6.516e-19	93.0	COG4720@1|root,COG4720@2|Bacteria,1VBBN@1239|Firmicutes,4HMK4@91061|Bacilli,3FBKC@33958|Lactobacillaceae	91061|Bacilli	S	Pfam:DUF3816	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
WH1_k127_10156661_1	33905.BTHE_0578	2.202e-104	355.0	COG1123@1|root,COG4172@2|Bacteria,2H2BQ@201174|Actinobacteria,4CZBA@85004|Bifidobacteriales	201174|Actinobacteria	P	AAA domain, putative AbiEii toxin, Type IV TA system	ykoD	-	-	ko:K16784,ko:K16786,ko:K16787	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
WH1_k127_10162066_1	926569.ANT_04510	8.496e-117	379.0	COG1013@1|root,COG1013@2|Bacteria,2G5VG@200795|Chloroflexi	200795|Chloroflexi	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WH1_k127_10162066_4	926569.ANT_04520	9.114e-73	249.0	COG1014@1|root,COG1014@2|Bacteria,2G6FV@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porG	-	1.2.7.1,1.2.7.3	ko:K00172,ko:K00177	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00307,M00374,M00620	R01196,R01197,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
WH1_k127_10162066_5	1713.JOFV01000007_gene3028	1.413e-18	90.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,4F2GA@85016|Cellulomonadaceae	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH1_k127_10162066_0	1128421.JAGA01000001_gene2386	2.334e-129	421.0	COG2132@1|root,COG2132@2|Bacteria,2NPD2@2323|unclassified Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1,DUF4396
WH1_k127_10162066_2	1128421.JAGA01000003_gene3536	9.11e-112	385.0	COG5002@1|root,COG5002@2|Bacteria,2NS5D@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WH1_k127_10162066_3	1128421.JAGA01000003_gene3537	3.179e-99	328.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WH1_k127_10178122_0	926569.ANT_14870	1.019e-269	849.0	COG0112@1|root,COG0404@1|root,COG0112@2|Bacteria,COG0404@2|Bacteria,2G624@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
WH1_k127_10178122_2	402777.KB235904_gene3543	2.081e-42	166.0	COG1357@1|root,COG1357@2|Bacteria,1G31P@1117|Cyanobacteria,1H7FG@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
WH1_k127_10178122_1	357808.RoseRS_0293	4.596e-72	264.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi,375Q4@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WH1_k127_10190030_1	926569.ANT_12630	1.366e-87	293.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
WH1_k127_10190030_0	926569.ANT_25290	0.0	1124.0	COG0653@1|root,COG0653@2|Bacteria,2G603@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WH1_k127_10192626_1	926569.ANT_09210	2.547e-73	258.0	COG0745@1|root,COG2114@1|root,COG5000@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP,dCache_1,dCache_3
WH1_k127_10192626_0	379066.GAU_1107	1.713e-156	513.0	COG0191@1|root,COG0191@2|Bacteria,1ZSZE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
WH1_k127_10192626_2	926569.ANT_20600	3.215e-38	150.0	arCOG05710@1|root,33AIT@2|Bacteria,2G9CR@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_10192626_3	926569.ANT_20590	9.182e-20	89.0	COG4260@1|root,COG4260@2|Bacteria,2G6J2@200795|Chloroflexi	200795|Chloroflexi	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17,zinc_ribbon_2
WH1_k127_1019742_2	886293.Sinac_4302	1.508e-28	130.0	COG3266@1|root,COG4655@1|root,COG4932@1|root,COG3266@2|Bacteria,COG4655@2|Bacteria,COG4932@2|Bacteria,2IZVN@203682|Planctomycetes	203682|Planctomycetes	M	Protein of unknown function (DUF3494)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DUF3494
WH1_k127_1019742_1	926550.CLDAP_06330	4.846e-40	161.0	COG2606@1|root,COG2606@2|Bacteria,2G931@200795|Chloroflexi	200795|Chloroflexi	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
WH1_k127_1019742_0	357808.RoseRS_2229	4.914e-67	252.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
WH1_k127_1019742_3	1353529.M899_2376	3.562e-06	59.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	ESPR,Peptidase_S74,YadA_anchor,YadA_head,YadA_stalk
WH1_k127_10199543_0	926569.ANT_16940	2.871e-82	300.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WH1_k127_10199543_1	926569.ANT_16900	2.39e-53	212.0	COG3852@1|root,COG3852@2|Bacteria,2G96T@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS
WH1_k127_10199543_2	926569.ANT_16890	6.92e-28	123.0	COG2204@1|root,COG2204@2|Bacteria,2G5ZP@200795|Chloroflexi	200795|Chloroflexi	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WH1_k127_10206266_1	742723.HMPREF9477_01408	1.88e-29	121.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,27IAJ@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WH1_k127_10206266_0	765869.BDW_03880	1.746e-52	194.0	COG2114@1|root,COG2770@1|root,COG2114@2|Bacteria,COG2770@2|Bacteria,1MV1V@1224|Proteobacteria,42SUQ@68525|delta/epsilon subdivisions,2MUNS@213481|Bdellovibrionales,2WPIY@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
WH1_k127_10208537_0	290315.Clim_1311	3.93e-57	207.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6,Hydrolase_4
WH1_k127_10208537_2	926550.CLDAP_28690	2.566e-06	51.0	COG3526@1|root,COG3526@2|Bacteria,2G7F3@200795|Chloroflexi	200795|Chloroflexi	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
WH1_k127_10208537_1	497965.Cyan7822_0874	1.188e-18	89.0	28HTA@1|root,2Z806@2|Bacteria,1G35E@1117|Cyanobacteria,3KJ5C@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_10210400_0	926569.ANT_11910	1.869e-69	243.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi	200795|Chloroflexi	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
WH1_k127_10210400_1	926569.ANT_31670	1.337e-42	163.0	COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi	200795|Chloroflexi	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
WH1_k127_10210400_2	926569.ANT_31660	5.492e-09	60.0	COG1214@1|root,COG1214@2|Bacteria,2G6VT@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M22 glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
WH1_k127_10254822_2	926569.ANT_03750	4.134e-42	161.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	ssuA	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
WH1_k127_10254822_1	926569.ANT_03740	1.718e-84	291.0	COG1116@1|root,COG1116@2|Bacteria,2G8SU@200795|Chloroflexi	200795|Chloroflexi	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
WH1_k127_10254822_0	926569.ANT_03730	2.208e-91	311.0	COG0600@1|root,COG0600@2|Bacteria,2G72A@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
WH1_k127_10257091_3	1282362.AEAC466_20715	1.235e-05	55.0	COG3794@1|root,COG3794@2|Bacteria,1RHQU@1224|Proteobacteria,2UBHY@28211|Alphaproteobacteria,2KGRB@204458|Caulobacterales	204458|Caulobacterales	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_10257091_1	1165841.SULAR_03003	1.706e-14	79.0	COG0674@1|root,COG1014@1|root,COG4892@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,COG4892@2|Bacteria,1NBSJ@1224|Proteobacteria,42MXV@68525|delta/epsilon subdivisions,2YRFR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Cyt-b5,POR,POR_N
WH1_k127_10257091_0	926569.ANT_18510	1.435e-97	331.0	COG2986@1|root,COG2986@2|Bacteria,2G66R@200795|Chloroflexi	200795|Chloroflexi	E	PFAM phenylalanine histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
WH1_k127_10257091_2	9713.XP_006740044.1	3.649e-12	78.0	COG0179@1|root,KOG2843@2759|Eukaryota,38HPV@33154|Opisthokonta,3BF5X@33208|Metazoa,3CT2E@33213|Bilateria,482BE@7711|Chordata,4937B@7742|Vertebrata,3JBCF@40674|Mammalia,3EN48@33554|Carnivora	33208|Metazoa	G	Fumarylacetoacetate hydrolase	FAH	GO:0003674,GO:0003824,GO:0004334,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006558,GO:0006559,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
WH1_k127_10269466_1	926550.CLDAP_22690	1.568e-24	104.0	COG1215@1|root,COG2148@1|root,COG1215@2|Bacteria,COG2148@2|Bacteria,2G866@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,Glycos_transf_2
WH1_k127_10269466_0	56110.Oscil6304_3528	2.165e-118	390.0	COG0451@1|root,COG0451@2|Bacteria,1G0QH@1117|Cyanobacteria,1H7R6@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM NAD dependent epimerase dehydratase family	-	-	4.1.1.35,5.1.3.2	ko:K01784,ko:K08678	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01384,R02984	RC00289,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WH1_k127_10269466_2	502025.Hoch_2199	5.574e-09	58.0	COG0463@1|root,COG0463@2|Bacteria,1QYVD@1224|Proteobacteria,43CR9@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH1_k127_10271595_1	1385520.N802_02155	7.506e-70	249.0	COG1486@1|root,COG1486@2|Bacteria,2GK80@201174|Actinobacteria,4FISU@85021|Intrasporangiaceae	201174|Actinobacteria	G	Family 4 glycosyl hydrolase	bglY	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
WH1_k127_10271595_0	477974.Daud_1728	1.343e-126	412.0	COG2202@1|root,COG2203@1|root,COG3437@1|root,COG3605@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3605@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,261WQ@186807|Peptococcaceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,HD,HD_5
WH1_k127_10280800_1	436229.JOEH01000029_gene4894	6.789e-05	49.0	COG3585@1|root,COG3585@2|Bacteria,2IKQV@201174|Actinobacteria,2NITC@228398|Streptacidiphilus	201174|Actinobacteria	H	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,MerR,TOBE
WH1_k127_10280800_0	1120945.ATUW01000003_gene169	4.201e-07	59.0	COG0526@1|root,COG0526@2|Bacteria,2I7I6@201174|Actinobacteria,4D8BZ@85005|Actinomycetales	201174|Actinobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WH1_k127_10281821_0	1463926.JOCA01000001_gene4754	4.134e-129	438.0	COG0764@1|root,COG3321@1|root,COG0764@2|Bacteria,COG3321@2|Bacteria,2GIVM@201174|Actinobacteria	201174|Actinobacteria	I	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA,KAsynt_C_assoc,Ketoacyl-synt_C,ketoacyl-synt
WH1_k127_10287787_0	926569.ANT_18400	1.185e-63	237.0	COG1287@1|root,COG1287@2|Bacteria,2G785@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_10287787_3	1033736.CAHK01000003_gene2567	9.032e-05	53.0	COG1579@1|root,COG1579@2|Bacteria,2HYSE@201174|Actinobacteria,4FAGV@85019|Brevibacteriaceae	201174|Actinobacteria	S	Zn-ribbon protein possibly nucleic acid-binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_10287787_1	926569.ANT_18420	7.269e-12	77.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	DNA_alkylation,GUN4,HEAT_2,Mrr_cat,NACHT
WH1_k127_10287787_2	338969.Rfer_0247	2.59e-05	51.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,4A9WN@80864|Comamonadaceae	28216|Betaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WH1_k127_10288383_1	926569.ANT_22920	1.202e-29	121.0	COG0759@1|root,COG0759@2|Bacteria,2G76Q@200795|Chloroflexi	200795|Chloroflexi	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
WH1_k127_10288383_0	926569.ANT_22910	3.078e-32	140.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_2,PQQ_3,Pkinase
WH1_k127_10288383_2	926569.ANT_22900	1.525e-08	57.0	COG0706@1|root,COG0706@2|Bacteria,2G6N0@200795|Chloroflexi	200795|Chloroflexi	U	PFAM 60 kDa inner membrane insertion protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
WH1_k127_1030879_2	292459.STH214	4.617e-90	305.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3	ko:K00074,ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R01976,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R05576,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N
WH1_k127_1030879_1	395494.Galf_1743	2.649e-99	327.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,2VHN3@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WH1_k127_1030879_3	479434.Sthe_2577	2.722e-73	255.0	COG1024@1|root,COG1024@2|Bacteria,2G6G6@200795|Chloroflexi	200795|Chloroflexi	I	PFAM Enoyl-CoA hydratase isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
WH1_k127_1030879_7	7245.FBpp0260894	8.603e-13	70.0	2D82N@1|root,2T8G1@2759|Eukaryota,3930P@33154|Opisthokonta,3C8AX@33208|Metazoa,3DPBM@33213|Bilateria,425JT@6656|Arthropoda,3SV54@50557|Insecta,4587U@7147|Diptera,45Z7T@7214|Drosophilidae	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_1030879_4	1157490.EL26_12265	1.049e-47	189.0	COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,279HE@186823|Alicyclobacillaceae	91061|Bacilli	F	5'-nucleotidase, C-terminal domain	yunD	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Metallophos
WH1_k127_1030879_0	316274.Haur_4751	3.249e-205	663.0	COG1164@1|root,COG1164@2|Bacteria,2G5UV@200795|Chloroflexi,376XT@32061|Chloroflexia	32061|Chloroflexia	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
WH1_k127_1030879_5	926569.ANT_10880	1.906e-31	134.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,DUF1906,PG_binding_1,Peptidase_M15_4
WH1_k127_10313129_2	477974.Daud_0731	3.151e-14	74.0	COG0823@1|root,COG0823@2|Bacteria,1V099@1239|Firmicutes,24FNQ@186801|Clostridia,260RC@186807|Peptococcaceae	186801|Clostridia	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
WH1_k127_10313129_1	1157637.KB892101_gene2502	8.039e-56	212.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WH1_k127_10313129_0	383372.Rcas_4420	1.167e-125	425.0	COG3039@1|root,COG3039@2|Bacteria,2G8AJ@200795|Chloroflexi,377UG@32061|Chloroflexia	32061|Chloroflexia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
WH1_k127_10313129_3	596323.HMPREF0554_1712	1.045e-08	59.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WH1_k127_10323760_2	316274.Haur_3307	4.908e-51	193.0	COG0002@1|root,COG0002@2|Bacteria,2G5W0@200795|Chloroflexi,374YZ@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde	lysY	-	-	ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh
WH1_k127_10323760_0	926569.ANT_12410	1.151e-132	428.0	COG0189@1|root,COG0189@2|Bacteria,2G5RN@200795|Chloroflexi	200795|Chloroflexi	HJ	Belongs to the RimK family	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
WH1_k127_10323760_3	867845.KI911784_gene2372	2.166e-14	82.0	2DRHT@1|root,33BTG@2|Bacteria,2G7I1@200795|Chloroflexi,37602@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM lysine biosynthesis protein LysW	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
WH1_k127_10323760_1	1128421.JAGA01000003_gene3441	5.65e-77	261.0	COG0137@1|root,COG0137@2|Bacteria,2NP01@2323|unclassified Bacteria	2|Bacteria	E	Arginosuccinate synthase	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.argG,iSB619.SA_RS04675	Arginosuc_synth
WH1_k127_10327385_1	314271.RB2654_20923	3.789e-93	317.0	COG1744@1|root,COG1744@2|Bacteria,1R7WA@1224|Proteobacteria,2U4T6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
WH1_k127_10327385_0	926569.ANT_27890	1.722e-178	567.0	COG3845@1|root,COG3845@2|Bacteria,2G625@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
WH1_k127_1034290_0	357808.RoseRS_2190	1.15e-215	691.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
WH1_k127_10365356_0	926550.CLDAP_23750	1.239e-134	439.0	COG0015@1|root,COG0015@2|Bacteria,2G607@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2,5.5.1.2	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	M00048,M00049	R01083,R03307,R04559	RC00379,RC00444,RC00445,RC00902	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
WH1_k127_10365356_3	383372.Rcas_1291	4.951e-92	313.0	COG1159@1|root,COG1159@2|Bacteria,2G69C@200795|Chloroflexi,3755E@32061|Chloroflexia	32061|Chloroflexia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
WH1_k127_10365356_2	926560.KE387027_gene362	1.712e-94	314.0	COG1738@1|root,COG1738@2|Bacteria,1WIRJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
WH1_k127_10365356_1	644966.Tmar_2076	5.135e-100	335.0	COG0037@1|root,COG0037@2|Bacteria,1UB13@1239|Firmicutes,249NH@186801|Clostridia	186801|Clostridia	H	Belongs to the TtcA family	-	-	2.8.1.15	ko:K21947	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
WH1_k127_10365356_4	771875.Ferpe_1606	6.473e-08	55.0	COG2104@1|root,COG2104@2|Bacteria,2GEBH@200918|Thermotogae	200918|Thermotogae	H	thiamine diphosphate biosynthetic process	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	-
WH1_k127_10376076_1	580327.Tthe_1660	1.08e-128	424.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42FF9@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase	bcd	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	1.3.1.108,1.3.8.1	ko:K00248,ko:K22430	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH1_k127_10376076_4	870187.Thini_1541	5.24e-07	63.0	COG2755@1|root,COG2885@1|root,COG2755@2|Bacteria,COG2885@2|Bacteria,1MX1F@1224|Proteobacteria,1RYU1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,OmpA
WH1_k127_10376076_2	1296415.JACC01000014_gene984	2.594e-54	215.0	COG0739@1|root,COG2273@1|root,COG3401@1|root,COG0739@2|Bacteria,COG2273@2|Bacteria,COG3401@2|Bacteria,4P1G2@976|Bacteroidetes,1I78P@117743|Flavobacteriia,2YKT3@290174|Aquimarina	976|Bacteroidetes	G	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_10376076_3	1111069.TCCBUS3UF1_3620	3.26e-54	205.0	COG2199@1|root,COG3706@2|Bacteria,1WIYY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
WH1_k127_10376076_0	477974.Daud_1728	7.26e-158	522.0	COG2202@1|root,COG2203@1|root,COG3437@1|root,COG3605@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3605@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,261WQ@186807|Peptococcaceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,HD,HD_5
WH1_k127_10376567_0	1128421.JAGA01000003_gene3084	1.234e-34	143.0	COG0619@1|root,COG0619@2|Bacteria,2NRVG@2323|unclassified Bacteria	2|Bacteria	P	PFAM Cobalt transport protein	cbiQ	GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02007,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
WH1_k127_10376567_1	926569.ANT_12690	1.271e-34	139.0	COG0310@1|root,COG0310@2|Bacteria,2G6ZN@200795|Chloroflexi	200795|Chloroflexi	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
WH1_k127_10381409_0	926569.ANT_11210	4.524e-177	569.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2G64T@200795|Chloroflexi	200795|Chloroflexi	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
WH1_k127_10388539_0	926569.ANT_05370	1.079e-85	291.0	COG2723@1|root,COG2723@2|Bacteria,2G5QE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
WH1_k127_10388539_1	1121877.JQKF01000014_gene40	1.156e-07	61.0	COG3393@1|root,COG3393@2|Bacteria,2IF2P@201174|Actinobacteria	201174|Actinobacteria	S	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
WH1_k127_10405701_1	1278078.G419_03043	5.756e-06	55.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria,4FWGA@85025|Nocardiaceae	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH1_k127_10405701_0	159749.K0R720	6.553e-10	71.0	KOG1192@1|root,KOG1192@2759|Eukaryota,2XE1V@2836|Bacillariophyta	2836|Bacillariophyta	CG	Glycosyltransferase family 28 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
WH1_k127_10419409_0	85643.Tmz1t_2959	0.0	1401.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VMWP@28216|Betaproteobacteria,2KVYZ@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.5.1,3.1.2.25	ko:K18361	ko00360,map00360	-	R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
WH1_k127_10419409_1	76114.ebA5395	1.151e-39	150.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria,2KVJP@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S binding domain	padC	-	-	ko:K18362	ko00360,map00360	-	R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001	-	-	-	Fer4_7
WH1_k127_10421576_0	1128421.JAGA01000004_gene2534	2.959e-16	87.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WH1_k127_10437191_2	926569.ANT_29070	3.682e-40	153.0	COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WH1_k127_10437191_1	1449069.JMLO01000016_gene3394	2.993e-45	169.0	COG0748@1|root,COG0748@2|Bacteria,2IFYD@201174|Actinobacteria,4G9EE@85025|Nocardiaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
WH1_k127_10437191_0	935948.KE386495_gene1891	3.013e-48	183.0	COG1807@1|root,COG1807@2|Bacteria,1TPGI@1239|Firmicutes,2483X@186801|Clostridia,42FZP@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WH1_k127_10441054_1	926550.CLDAP_30410	4.811e-06	54.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,2G8CU@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF348,G5
WH1_k127_10441054_0	565045.NOR51B_1838	1.113e-07	63.0	COG4942@1|root,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,1J66Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Lysin motif	nlpD	GO:0000920,GO:0001896,GO:0005575,GO:0005623,GO:0008150,GO:0008219,GO:0009279,GO:0009987,GO:0012501,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0043085,GO:0044093,GO:0044462,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071944	-	ko:K06194,ko:K12943	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
WH1_k127_10463972_4	880072.Desac_1289	9.839e-06	52.0	2EHRH@1|root,33BH9@2|Bacteria,1NNFQ@1224|Proteobacteria,432S0@68525|delta/epsilon subdivisions,2WY20@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4926)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4926
WH1_k127_10463972_5	1385935.N836_16850	3.744e-05	48.0	2E953@1|root,333DW@2|Bacteria,1G8VT@1117|Cyanobacteria,1HFXG@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_10463972_2	292459.STH2483	8.764e-50	182.0	COG2151@1|root,COG2151@2|Bacteria,1V3QG@1239|Firmicutes,2528Q@186801|Clostridia	186801|Clostridia	S	Pfam:DUF59	-	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
WH1_k127_10463972_1	1124780.ANNU01000021_gene3019	5.282e-73	260.0	COG3396@1|root,COG3396@2|Bacteria,4NFIT@976|Bacteroidetes,47VWV@768503|Cytophagia	976|Bacteroidetes	S	Phenylacetic acid catabolic protein	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
WH1_k127_10463972_3	485918.Cpin_0788	8.097e-24	103.0	COG3460@1|root,COG3460@2|Bacteria,4NQFV@976|Bacteroidetes	976|Bacteroidetes	Q	Phenylacetate-CoA oxygenase	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
WH1_k127_10463972_0	1237149.C900_04821	4.827e-138	442.0	COG3396@1|root,COG3396@2|Bacteria,4NFJN@976|Bacteroidetes,47TVD@768503|Cytophagia	976|Bacteroidetes	S	Phenylacetic acid catabolic protein	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
WH1_k127_10478628_1	479434.Sthe_2929	3.373e-32	128.0	COG0044@1|root,COG0044@2|Bacteria,2G5N4@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	3.5.2.2,3.5.2.5	ko:K01464,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00546	R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
WH1_k127_10478628_0	1121918.ARWE01000001_gene385	3.957e-207	657.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WTRK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
WH1_k127_10508311_1	215803.DB30_6260	3.949e-46	176.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria,1QX5Y@1224|Proteobacteria,42PKC@68525|delta/epsilon subdivisions,2WISI@28221|Deltaproteobacteria,2YYJ2@29|Myxococcales	28221|Deltaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA
WH1_k127_10508311_0	1499967.BAYZ01000076_gene800	1.76e-59	218.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K02012,ko:K07114	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	1.A.13.2.2,1.A.13.2.3,3.A.1.10	-	-	SBP_bac_11,VWA,VWA_2,VWA_3
WH1_k127_10514117_0	388413.ALPR1_05140	2.358e-97	325.0	COG1235@1|root,COG1235@2|Bacteria,4NM16@976|Bacteroidetes,47U32@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
WH1_k127_10514117_2	247490.KSU1_C1650	0.0002458	47.0	COG3350@1|root,COG3350@2|Bacteria	2|Bacteria	T	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	YHS
WH1_k127_10514117_1	1168034.FH5T_08655	1.103e-75	260.0	COG0434@1|root,COG0434@2|Bacteria,4P0R6@976|Bacteroidetes	976|Bacteroidetes	S	BtpA family	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
WH1_k127_1051855_1	1122223.KB890687_gene2522	2.63e-56	202.0	COG0656@1|root,COG0656@2|Bacteria,1WIXH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WH1_k127_1051855_0	765420.OSCT_2101	4.048e-230	723.0	COG2303@1|root,COG2303@2|Bacteria,2G7EB@200795|Chloroflexi	200795|Chloroflexi	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
WH1_k127_10519468_2	1303518.CCALI_00397	1.557e-30	124.0	COG2423@1|root,COG2423@2|Bacteria	2|Bacteria	E	ornithine cyclodeaminase activity	ocd	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
WH1_k127_10519468_0	926550.CLDAP_32690	3.294e-232	739.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,2G7SW@200795|Chloroflexi	200795|Chloroflexi	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
WH1_k127_10519468_1	1122135.KB893141_gene61	9.963e-88	294.0	COG5012@1|root,COG5012@2|Bacteria,1RDEU@1224|Proteobacteria,2TVXN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	cobalamin binding protein	mtbC	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
WH1_k127_1051950_3	324602.Caur_3251	8.359e-56	209.0	COG0500@1|root,COG2226@2|Bacteria,2G9F9@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_1051950_0	269797.Mbar_A0373	2.345e-85	308.0	COG0438@1|root,arCOG05174@2157|Archaea,2XX01@28890|Euryarchaeota,2N9IX@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
WH1_k127_1051950_2	211165.AJLN01000116_gene2993	2.627e-65	238.0	COG0438@1|root,COG0438@2|Bacteria,1G6YR@1117|Cyanobacteria,1JIY3@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
WH1_k127_1051950_1	246197.MXAN_5333	3.516e-68	246.0	COG0438@1|root,COG0438@2|Bacteria,1RM3H@1224|Proteobacteria,42WAY@68525|delta/epsilon subdivisions,2WRXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
WH1_k127_1051950_4	644282.Deba_0452	1.056e-24	106.0	COG0438@1|root,COG0438@2|Bacteria,1RM3H@1224|Proteobacteria,42WAY@68525|delta/epsilon subdivisions,2WRXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
WH1_k127_10555243_2	926550.CLDAP_17580	9.058e-72	257.0	COG0728@1|root,COG0728@2|Bacteria,2G5PF@200795|Chloroflexi	200795|Chloroflexi	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
WH1_k127_10555243_0	1254432.SCE1572_02095	8.521e-206	659.0	COG1226@1|root,COG1226@2|Bacteria,1MV0T@1224|Proteobacteria,43DUN@68525|delta/epsilon subdivisions,2WYXG@28221|Deltaproteobacteria,2Z0V5@29|Myxococcales	28221|Deltaproteobacteria	P	Castor and Pollux, part of voltage-gated ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Castor_Poll_mid
WH1_k127_10555243_3	105425.BBPL01000003_gene6797	3.016e-14	79.0	2E8T5@1|root,3333Y@2|Bacteria,2IS1D@201174|Actinobacteria,2NJJ6@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_10555243_1	646529.Desaci_2502	3.365e-107	352.0	COG0412@1|root,COG0412@2|Bacteria,1UZRU@1239|Firmicutes	1239|Firmicutes	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
WH1_k127_1056410_0	1341151.ASZU01000010_gene1938	1.511e-55	216.0	COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,1UWW7@1239|Firmicutes,4INA2@91061|Bacilli,27CJS@186824|Thermoactinomycetaceae	91061|Bacilli	Q	Polyketide synthase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KR,Ketoacyl-synt_C,PS-DH,ketoacyl-synt
WH1_k127_10571625_1	383372.Rcas_0732	2.076e-10	72.0	COG0793@1|root,COG4585@1|root,COG0793@2|Bacteria,COG4585@2|Bacteria,2GAQQ@200795|Chloroflexi,3772Z@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
WH1_k127_10571625_0	472759.Nhal_0228	1.393e-16	86.0	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,1RS0G@1236|Gammaproteobacteria,1WZSK@135613|Chromatiales	135613|Chromatiales	KT	PFAM PspA IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
WH1_k127_10575413_0	926569.ANT_31200	2.009e-48	197.0	COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
WH1_k127_10584357_0	926569.ANT_18310	4.333e-293	915.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi	200795|Chloroflexi	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WH1_k127_10584357_2	926569.ANT_18300	1.404e-22	104.0	COG0071@1|root,COG0071@2|Bacteria,2G7BB@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
WH1_k127_10584357_1	326427.Cagg_0772	3.584e-26	117.0	COG0664@1|root,COG0664@2|Bacteria,2GBTI@200795|Chloroflexi,375RB@32061|Chloroflexia	32061|Chloroflexia	T	PFAM cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
WH1_k127_10592949_0	525904.Tter_2275	9.404e-102	340.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WH1_k127_10592949_1	215803.DB30_4039	1.773e-13	73.0	COG2382@1|root,COG2382@2|Bacteria,1MXJN@1224|Proteobacteria,437I8@68525|delta/epsilon subdivisions,2X38I@28221|Deltaproteobacteria,2YVT6@29|Myxococcales	28221|Deltaproteobacteria	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
WH1_k127_1059790_0	357808.RoseRS_2190	4.523e-115	399.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
WH1_k127_10620076_0	765420.OSCT_0754	7.986e-134	437.0	COG1132@1|root,COG1132@2|Bacteria,2G7J5@200795|Chloroflexi,3758C@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WH1_k127_10622831_2	926550.CLDAP_26560	6.893e-51	184.0	COG0577@1|root,COG0577@2|Bacteria,2G5WX@200795|Chloroflexi	200795|Chloroflexi	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
WH1_k127_10622831_0	383372.Rcas_4355	6.708e-93	320.0	COG1136@1|root,COG1136@2|Bacteria,2G5S3@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WH1_k127_10622831_1	926550.CLDAP_26540	5.176e-72	250.0	COG1136@1|root,COG1136@2|Bacteria,2G6FP@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH1_k127_10622831_3	38727.Pavir.Ab00288.1.p	3.365e-17	87.0	COG1472@1|root,2QQ55@2759|Eukaryota,37HYI@33090|Viridiplantae,3G89A@35493|Streptophyta,3M4Y3@4447|Liliopsida,3IFRA@38820|Poales	35493|Streptophyta	G	Glycosyl hydrolase family 3 N terminal domain	-	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008422,GO:0009056,GO:0009057,GO:0009251,GO:0015926,GO:0016020,GO:0016052,GO:0016787,GO:0016798,GO:0042597,GO:0043170,GO:0044042,GO:0044238,GO:0044464,GO:0071704,GO:0071944,GO:1901575	3.2.1.21	ko:K01188,ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH1,GH3	-	Glyco_hydro_3,Glyco_hydro_3_C
WH1_k127_10637220_0	357808.RoseRS_1205	2.251e-75	268.0	COG1572@1|root,COG1572@2|Bacteria,2G7MU@200795|Chloroflexi,374XB@32061|Chloroflexia	32061|Chloroflexia	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
WH1_k127_10637220_1	713586.KB900536_gene2793	2.259e-36	148.0	COG1361@1|root,COG1361@2|Bacteria,1QVSF@1224|Proteobacteria,1T2IX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_10644335_1	868131.MSWAN_0159	1.63e-24	116.0	COG1807@1|root,arCOG00566@2157|Archaea	2157|Archaea	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT_2
WH1_k127_10644335_0	234267.Acid_5231	1.711e-64	227.0	COG0213@1|root,COG0213@2|Bacteria,3Y44B@57723|Acidobacteria	57723|Acidobacteria	F	PFAM Glycosyl transferase, family	-	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
WH1_k127_10653536_1	926569.ANT_18700	9.445e-85	291.0	COG0457@1|root,COG0457@2|Bacteria,2G70Z@200795|Chloroflexi	200795|Chloroflexi	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_1,TPR_16,TPR_19,TPR_8
WH1_k127_10653536_0	357808.RoseRS_3190	2.145e-87	297.0	COG0123@1|root,COG0123@2|Bacteria,2G5X3@200795|Chloroflexi,374Z1@32061|Chloroflexia	32061|Chloroflexia	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
WH1_k127_10656139_3	926554.KI912657_gene4393	1.08e-20	91.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WH1_k127_10656139_1	926550.CLDAP_05650	3.902e-54	196.0	COG0673@1|root,COG0673@2|Bacteria,2G5MT@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WH1_k127_10656139_2	1380346.JNIH01000006_gene3582	4.353e-50	190.0	COG1082@1|root,COG1082@2|Bacteria,2IH92@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
WH1_k127_10656139_0	383372.Rcas_2620	7.079e-104	342.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi,376Z5@32061|Chloroflexia	32061|Chloroflexia	H	PFAM carbohydrate kinase, FGGY	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
WH1_k127_10657707_1	926569.ANT_14490	2.31e-163	530.0	COG1319@1|root,COG2080@1|root,COG1319@2|Bacteria,COG2080@2|Bacteria,2G5XD@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
WH1_k127_10657707_4	926569.ANT_25970	5.659e-35	139.0	COG2050@1|root,COG2050@2|Bacteria,2G751@200795|Chloroflexi	200795|Chloroflexi	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WH1_k127_10657707_0	926569.ANT_14450	2.851e-165	524.0	COG2141@1|root,COG2141@2|Bacteria,2G727@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
WH1_k127_10657707_3	926569.ANT_14440	2.419e-35	142.0	COG1920@1|root,COG1920@2|Bacteria,2G76R@200795|Chloroflexi	200795|Chloroflexi	H	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
WH1_k127_10657707_2	450851.PHZ_c2538	1.055e-94	318.0	COG0391@1|root,COG0391@2|Bacteria,1NK78@1224|Proteobacteria,2TUUA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	LPPG Fo 2-phospho-L-lactate transferase	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
WH1_k127_10665178_2	926569.ANT_13860	1.607e-40	158.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
WH1_k127_10665178_3	926569.ANT_13850	1.307e-22	104.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_13850|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_10665178_1	479434.Sthe_1010	3.217e-52	201.0	COG0226@1|root,COG2843@1|root,COG0226@2|Bacteria,COG2843@2|Bacteria,2G78I@200795|Chloroflexi,27Z2P@189775|Thermomicrobia	189775|Thermomicrobia	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
WH1_k127_10665178_5	908339.HMPREF9265_0449	8.975e-13	77.0	COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,1UYRM@1239|Firmicutes,4HAU6@91061|Bacilli,3F4XJ@33958|Lactobacillaceae	91061|Bacilli	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	3.2.1.17	ko:K01185,ko:K02395,ko:K19223	-	-	-	-	ko00000,ko01000,ko01002,ko01011,ko02035	-	CBM50	-	Glucosaminidase,LysM
WH1_k127_10665178_4	869210.Marky_1036	4.335e-17	82.0	COG3350@1|root,COG3350@2|Bacteria,1WN5Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
WH1_k127_10665178_0	926569.ANT_29800	1.458e-173	552.0	COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
WH1_k127_10670859_0	926550.CLDAP_01930	2.926e-102	353.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
WH1_k127_10677653_0	926550.CLDAP_26330	0.0005102	53.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,PPC,Peptidase_M6
WH1_k127_10702869_1	357808.RoseRS_3117	5.806e-38	151.0	COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi,375N3@32061|Chloroflexia	32061|Chloroflexia	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
WH1_k127_10702869_0	926569.ANT_16100	2.386e-195	622.0	COG1418@1|root,COG4372@1|root,COG1418@2|Bacteria,COG4372@2|Bacteria,2G620@200795|Chloroflexi	200795|Chloroflexi	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
WH1_k127_10723096_0	56110.Oscil6304_4195	1.845e-24	119.0	COG1413@1|root,COG1413@2|Bacteria,1G233@1117|Cyanobacteria,1H7RE@1150|Oscillatoriales	1117|Cyanobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
WH1_k127_10723096_1	635013.TherJR_1499	9.657e-12	66.0	COG2199@1|root,COG3706@2|Bacteria,1UHZ8@1239|Firmicutes,25E7W@186801|Clostridia	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
WH1_k127_10732825_0	926569.ANT_16370	2.645e-40	155.0	COG0406@1|root,COG0406@2|Bacteria,2G7D2@200795|Chloroflexi	200795|Chloroflexi	G	Histidine phosphatase superfamily (branch 1)	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
WH1_k127_10742306_2	1121377.KB906409_gene857	7.331e-20	103.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
WH1_k127_10742306_3	1355368.JART01000012_gene513	1.919e-12	78.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2YMTD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WH1_k127_10742306_0	926569.ANT_13220	9.3e-181	584.0	COG0018@1|root,COG0018@2|Bacteria,2G6DK@200795|Chloroflexi	200795|Chloroflexi	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
WH1_k127_10742306_1	926569.ANT_13210	4.504e-166	528.0	COG2403@1|root,COG2403@2|Bacteria,2G7VS@200795|Chloroflexi	200795|Chloroflexi	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_10750049_2	926550.CLDAP_05920	1.365e-47	178.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
WH1_k127_10750049_0	926569.ANT_12730	9.931e-162	525.0	COG0520@1|root,COG0520@2|Bacteria,2G5W7@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WH1_k127_10750049_1	926569.ANT_01360	4.323e-76	262.0	COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi	200795|Chloroflexi	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
WH1_k127_10750049_4	401526.TcarDRAFT_2543	2.847e-11	69.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4H4S9@909932|Negativicutes	909932|Negativicutes	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
WH1_k127_10750049_3	926569.ANT_01340	1.276e-23	111.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
WH1_k127_10750936_0	469383.Cwoe_0425	2.363e-08	67.0	COG2815@1|root,COG3291@1|root,COG2815@2|Bacteria,COG3291@2|Bacteria,2I9UB@201174|Actinobacteria,4CTSN@84995|Rubrobacteria	84995|Rubrobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
WH1_k127_1078171_1	485915.Dret_0173	4.448e-08	58.0	COG1977@1|root,COG1977@2|Bacteria,1NH6M@1224|Proteobacteria,42X05@68525|delta/epsilon subdivisions,2WSK5@28221|Deltaproteobacteria,2MD55@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM ThiamineS	-	-	-	-	-	-	-	-	-	-	-	-	ThiS,Ub-Mut7C
WH1_k127_1078171_0	926569.ANT_16390	3.009e-35	139.0	2FJCP@1|root,34B2I@2|Bacteria,2G94J@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_10796798_1	1173027.Mic7113_0440	3.479e-70	242.0	COG1352@1|root,COG1352@2|Bacteria,1G1E5@1117|Cyanobacteria,1H94K@1150|Oscillatoriales	1117|Cyanobacteria	NT	PFAM CheR methyltransferase, SAM binding domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
WH1_k127_10796798_2	7245.FBpp0260894	7.831e-10	61.0	2D82N@1|root,2T8G1@2759|Eukaryota,3930P@33154|Opisthokonta,3C8AX@33208|Metazoa,3DPBM@33213|Bilateria,425JT@6656|Arthropoda,3SV54@50557|Insecta,4587U@7147|Diptera,45Z7T@7214|Drosophilidae	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_10796798_0	756067.MicvaDRAFT_0974	1.926e-277	871.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG1511@1|root,COG2770@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG1511@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,1G13T@1117|Cyanobacteria,1HI4W@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,Response_reg
WH1_k127_10810366_0	403833.Pmob_0722	1.448e-141	463.0	COG0383@1|root,COG0383@2|Bacteria,2GC0D@200918|Thermotogae	200918|Thermotogae	G	Glycoside hydrolase family 38 central region	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
WH1_k127_10821999_2	926550.CLDAP_07190	1.697e-07	60.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	nosY	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
WH1_k127_10821999_0	479434.Sthe_0737	2.097e-166	552.0	COG1131@1|root,COG3420@1|root,COG1131@2|Bacteria,COG3420@2|Bacteria,2G7PN@200795|Chloroflexi,27Z0E@189775|Thermomicrobia	189775|Thermomicrobia	P	Domain present in carbohydrate binding proteins and sugar hydrolses	-	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	ABC_tran,NosD
WH1_k127_10821999_1	926550.CLDAP_07160	1.36e-64	227.0	COG4314@1|root,COG4314@2|Bacteria	2|Bacteria	C	lipoprotein involved in nitrous oxide reduction	nosL	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
WH1_k127_10822939_0	1128421.JAGA01000003_gene3523	5.532e-17	92.0	COG0318@1|root,COG0318@2|Bacteria,2NR5F@2323|unclassified Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	MA20_41400	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
WH1_k127_10828320_1	479434.Sthe_1690	5.811e-44	164.0	COG1625@1|root,COG1625@2|Bacteria,2G5XW@200795|Chloroflexi	200795|Chloroflexi	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
WH1_k127_10828320_0	861299.J421_2390	6.934e-45	168.0	COG0604@1|root,COG0604@2|Bacteria,1ZT6R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
WH1_k127_10830605_1	45157.CME023CT	7.615e-24	108.0	COG0152@1|root,KOG2835@2759|Eukaryota	2759|Eukaryota	F	phosphoribosylaminoimidazole carboxylase activity	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009719,GO:0009725,GO:0009733,GO:0009987,GO:0010033,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
WH1_k127_10830605_0	243275.TDE_0686	1.182e-127	415.0	COG0152@1|root,COG0152@2|Bacteria,2J6XZ@203691|Spirochaetes	203691|Spirochaetes	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
WH1_k127_10842589_0	118161.KB235920_gene5993	3.67e-159	527.0	COG0464@1|root,COG0464@2|Bacteria,1G1YA@1117|Cyanobacteria,3VNFJ@52604|Pleurocapsales	1117|Cyanobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
WH1_k127_10842589_1	383372.Rcas_3701	1.514e-51	201.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GAAG@200795|Chloroflexi,374S4@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
WH1_k127_10880874_0	1245469.S58_56120	2.303e-25	114.0	2DPHF@1|root,33237@2|Bacteria,1R4GY@1224|Proteobacteria,2TUGA@28211|Alphaproteobacteria,3JSZU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase
WH1_k127_10880874_1	1144312.PMI09_01583	9.404e-13	76.0	COG2020@1|root,COG2020@2|Bacteria,1RECR@1224|Proteobacteria,2U6MH@28211|Alphaproteobacteria,4BA0U@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
WH1_k127_10896017_0	926569.ANT_20700	1.025e-95	325.0	COG4262@1|root,COG4262@2|Bacteria,2G5YS@200795|Chloroflexi	200795|Chloroflexi	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
WH1_k127_10900742_0	240015.ACP_3311	3.239e-117	389.0	COG3185@1|root,COG3185@2|Bacteria,3Y2ST@57723|Acidobacteria,2JISR@204432|Acidobacteriia	204432|Acidobacteriia	E	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
WH1_k127_10900742_2	316274.Haur_2760	6.152e-84	288.0	COG0834@1|root,COG0834@2|Bacteria,2G6HE@200795|Chloroflexi,376SS@32061|Chloroflexia	32061|Chloroflexia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
WH1_k127_10900742_3	926550.CLDAP_10830	9.904e-76	264.0	COG0765@1|root,COG0765@2|Bacteria,2G6IJ@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
WH1_k127_10900742_1	926569.ANT_12170	3.541e-98	327.0	COG1126@1|root,COG1126@2|Bacteria,2G5UB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	3.6.3.21	ko:K02028,ko:K09972	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
WH1_k127_10905890_0	926569.ANT_04510	4.593e-116	380.0	COG1013@1|root,COG1013@2|Bacteria,2G5VG@200795|Chloroflexi	200795|Chloroflexi	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WH1_k127_10905890_1	926569.ANT_04500	1.297e-19	89.0	COG0674@1|root,COG0674@2|Bacteria,2G5UG@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WH1_k127_1097456_2	926550.CLDAP_29450	1.341e-18	94.0	COG0508@1|root,COG0508@2|Bacteria,2G6A9@200795|Chloroflexi	200795|Chloroflexi	C	Catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WH1_k127_1097456_0	926550.CLDAP_29460	3.961e-133	436.0	COG0022@1|root,COG0022@2|Bacteria,2G60F@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Transketolase central region	-	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
WH1_k127_1097456_1	1128421.JAGA01000003_gene3315	2.522e-120	394.0	COG1071@1|root,COG1071@2|Bacteria,2NQNM@2323|unclassified Bacteria	2|Bacteria	C	Dehydrogenase E1 component	acoA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
WH1_k127_1114342_0	869210.Marky_0500	1.261e-138	452.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
WH1_k127_1114342_1	720554.Clocl_0789	8.204e-08	61.0	COG0407@1|root,COG0407@2|Bacteria,1V4WM@1239|Firmicutes,24IZV@186801|Clostridia,3WP8J@541000|Ruminococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
WH1_k127_1116443_0	572477.Alvin_0031	7.49e-193	624.0	COG0187@1|root,COG1372@1|root,COG0187@2|Bacteria,COG1372@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1WVZ4@135613|Chromatiales	135613|Chromatiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WH1_k127_1116443_1	1382306.JNIM01000001_gene2893	1.26e-82	282.0	COG4948@1|root,COG4948@2|Bacteria,2G8E6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Mandelate racemase muconate lactonizing protein	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
WH1_k127_1144495_0	926550.CLDAP_04460	3.403e-15	89.0	COG1807@1|root,COG1807@2|Bacteria,2G8YZ@200795|Chloroflexi	200795|Chloroflexi	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_1144495_1	1128421.JAGA01000002_gene1599	3.19e-07	63.0	COG1807@1|root,COG1807@2|Bacteria,2NRMD@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WH1_k127_1156461_1	926569.ANT_05270	1.434e-42	164.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi	200795|Chloroflexi	S	Electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
WH1_k127_1156461_0	926569.ANT_05280	1.133e-79	272.0	COG1845@1|root,COG1845@2|Bacteria,2G74U@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
WH1_k127_1156461_3	926550.CLDAP_10610	4.449e-10	60.0	COG0843@1|root,COG0843@2|Bacteria,2G5XS@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
WH1_k127_1170337_1	926569.ANT_06130	6.389e-72	257.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,LysM,YkuD
WH1_k127_1170337_2	926569.ANT_06130	2.304e-46	191.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,LysM,YkuD
WH1_k127_1170337_0	530564.Psta_1177	7.34e-74	259.0	COG2040@1|root,COG2040@2|Bacteria,2J3GR@203682|Planctomycetes	203682|Planctomycetes	H	Homocysteine S-methyltransferase	-	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
WH1_k127_117108_0	309801.trd_0440	1.852e-99	328.0	COG2006@1|root,COG2006@2|Bacteria,2GA2Y@200795|Chloroflexi,27YWH@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
WH1_k127_1186699_2	1547437.LL06_17650	6.426e-15	74.0	COG1176@1|root,COG1176@2|Bacteria,1NU6V@1224|Proteobacteria,2TU7Q@28211|Alphaproteobacteria,43ITE@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	ABC-type spermidine putrescine transport system, permease component I	ydcU	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
WH1_k127_1186699_1	1500259.JQLD01000002_gene3052	9.719e-113	370.0	COG1177@1|root,COG1177@2|Bacteria,1N3TB@1224|Proteobacteria,2U23R@28211|Alphaproteobacteria,4B8ND@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	ABC transporter permease	ydcV	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
WH1_k127_1186699_0	926550.CLDAP_05420	9.86e-142	458.0	COG0160@1|root,COG0160@2|Bacteria,2G5SK@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WH1_k127_1186943_2	383372.Rcas_2615	1e-65	233.0	COG1082@1|root,COG1082@2|Bacteria,2G5V7@200795|Chloroflexi	200795|Chloroflexi	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
WH1_k127_1186943_0	1128421.JAGA01000001_gene2205	1.121e-134	433.0	COG5564@1|root,COG5564@2|Bacteria	2|Bacteria	S	Phosphoenolpyruvate hydrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	PEP_hydrolase
WH1_k127_1186943_1	1341151.ASZU01000012_gene1683	4.031e-101	334.0	COG5441@1|root,COG5441@2|Bacteria,1TQ3W@1239|Firmicutes,4HATW@91061|Bacilli,27BD5@186824|Thermoactinomycetaceae	91061|Bacilli	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
WH1_k127_1187438_0	1191523.MROS_1372	1.564e-107	353.0	COG1866@1|root,COG1866@2|Bacteria	2|Bacteria	H	phosphoenolpyruvate carboxykinase (ATP) activity	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
WH1_k127_1192530_0	926569.ANT_10240	8.27e-80	271.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi	200795|Chloroflexi	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
WH1_k127_1192530_2	1430331.EP10_11660	8.455e-64	225.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,1WFU3@129337|Geobacillus	91061|Bacilli	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
WH1_k127_1192530_1	562970.Btus_0175	9.638e-77	273.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,277XD@186823|Alicyclobacillaceae	91061|Bacilli	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WH1_k127_1192530_3	926569.ANT_10270	2.308e-12	66.0	COG0257@1|root,COG0257@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
WH1_k127_1192530_4	43989.cce_4037	5.622e-08	55.0	COG0099@1|root,COG0099@2|Bacteria,1G5S9@1117|Cyanobacteria,3KI0R@43988|Cyanothece	1117|Cyanobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
WH1_k127_1207680_0	1128421.JAGA01000003_gene2779	4.765e-108	359.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
WH1_k127_1207680_1	289376.THEYE_A1214	5.674e-17	82.0	COG0382@1|root,COG0382@2|Bacteria,3J0TY@40117|Nitrospirae	40117|Nitrospirae	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
WH1_k127_1207710_1	926569.ANT_04690	3.812e-28	115.0	COG1079@1|root,COG1079@2|Bacteria,2G6CY@200795|Chloroflexi	200795|Chloroflexi	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WH1_k127_1207710_0	926569.ANT_04700	1.523e-133	431.0	COG4603@1|root,COG4603@2|Bacteria,2G686@200795|Chloroflexi	200795|Chloroflexi	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WH1_k127_1234394_0	1192034.CAP_7461	1.977e-112	376.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42NYJ@68525|delta/epsilon subdivisions,2WKWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
WH1_k127_1234766_1	1051632.TPY_2633	1.105e-15	79.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
WH1_k127_1234766_0	1051632.TPY_2632	1.004e-116	383.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1TRNK@1239|Firmicutes,24B7I@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
WH1_k127_1242261_2	290398.Csal_2767	1.351e-06	52.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,1XIN1@135619|Oceanospirillales	135619|Oceanospirillales	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
WH1_k127_1242261_0	326427.Cagg_3135	2.243e-76	264.0	COG1091@1|root,COG1091@2|Bacteria,2G6NS@200795|Chloroflexi,375G0@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
WH1_k127_1242261_1	926550.CLDAP_13110	1.388e-42	159.0	COG1216@1|root,COG1216@2|Bacteria,2G66T@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH1_k127_1242418_0	324602.Caur_1030	5.642e-107	355.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi,374SC@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH1_k127_1242418_1	699218.HMPREF0889_1129	3.24e-19	99.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,4H2QE@909932|Negativicutes	909932|Negativicutes	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
WH1_k127_1261689_0	926550.CLDAP_25240	2.486e-29	129.0	COG1547@1|root,COG3437@1|root,COG1547@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	ypuF	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309,HD
WH1_k127_1310571_0	867845.KI911784_gene1365	4.607e-67	246.0	COG0823@1|root,COG3693@1|root,COG0823@2|Bacteria,COG3693@2|Bacteria,2GA75@200795|Chloroflexi,37735@32061|Chloroflexia	32061|Chloroflexia	U	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_1310571_1	1521187.JPIM01000063_gene2484	5.115e-47	184.0	COG0823@1|root,COG3693@1|root,COG0823@2|Bacteria,COG3693@2|Bacteria,2GA75@200795|Chloroflexi,37735@32061|Chloroflexia	32061|Chloroflexia	U	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_1345743_0	1229203.KI301992_gene2724	1.754e-43	184.0	COG2114@1|root,COG2114@2|Bacteria,2GJRI@201174|Actinobacteria,3UX9H@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1319c	Guanylate_cyc,HAMP
WH1_k127_1345743_4	498211.CJA_1579	1.626e-07	53.0	COG1192@1|root,COG1192@2|Bacteria,1R6KZ@1224|Proteobacteria,1S9NU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
WH1_k127_1345743_3	1174528.JH992888_gene257	5.575e-10	66.0	COG1569@1|root,COG1569@2|Bacteria,1GKQR@1117|Cyanobacteria,1JMK8@1189|Stigonemataceae	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
WH1_k127_1345743_1	760568.Desku_3205	1.73e-25	110.0	COG1743@1|root,COG1743@2|Bacteria,1TRIT@1239|Firmicutes,24AVX@186801|Clostridia,262DB@186807|Peptococcaceae	186801|Clostridia	L	DNA methylase	-	-	-	ko:K07445	-	-	-	-	ko00000	-	-	-	DUF1156
WH1_k127_1345743_2	255470.cbdbA109	1.797e-17	85.0	COG0326@1|root,COG0326@2|Bacteria,2G9ND@200795|Chloroflexi	200795|Chloroflexi	O	Molecular chaperone. Has ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_1350104_1	525904.Tter_0834	2.414e-42	160.0	COG0019@1|root,COG0019@2|Bacteria,2NNQK@2323|unclassified Bacteria	2|Bacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.1.129,3.4.16.4,4.1.1.20	ko:K01586,ko:K05366	ko00300,ko00550,ko01100,ko01110,ko01120,ko01130,ko01230,ko01501,map00300,map00550,map01100,map01110,map01120,map01130,map01230,map01501	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000,ko01003,ko01011	-	GT51	iLJ478.TM1517	Orn_Arg_deC_N,Orn_DAP_Arg_deC
WH1_k127_1350104_3	6238.CBG08811	0.0002798	45.0	2EW74@1|root,2SY2K@2759|Eukaryota,3AVH6@33154|Opisthokonta,3C40D@33208|Metazoa,3DKPN@33213|Bilateria,40Q8N@6231|Nematoda,1M0JK@119089|Chromadorea,416DZ@6236|Rhabditida	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_1350104_0	926569.ANT_31280	1.669e-47	175.0	COG4087@1|root,COG4087@2|Bacteria,2G99M@200795|Chloroflexi	200795|Chloroflexi	S	Haloacid dehalogenase domain protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WH1_k127_1357071_0	926569.ANT_16400	4.631e-111	374.0	2EYH8@1|root,33RR4@2|Bacteria,2G7WE@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_1373805_1	926569.ANT_26470	5.294e-11	68.0	COG2848@1|root,COG2848@2|Bacteria,2G6HQ@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterised ACR (DUF711)	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
WH1_k127_1373805_0	930945.SiRe_0548	3.87e-67	237.0	COG1506@1|root,arCOG01646@2157|Archaea,2XQMK@28889|Crenarchaeota	28889|Crenarchaeota	E	Peptidase S9 prolyl oligopeptidase active site domain protein	apeH-1	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WH1_k127_1373853_0	1385935.N836_28980	3.064e-54	200.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WH1_k127_1383645_1	765420.OSCT_1520	2.452e-40	158.0	COG2025@1|root,COG2025@2|Bacteria,2G6PP@200795|Chloroflexi,376P0@32061|Chloroflexia	32061|Chloroflexia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
WH1_k127_1383645_0	909663.KI867150_gene2942	1.322e-62	226.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WM55@28221|Deltaproteobacteria,2MQDQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
WH1_k127_1383645_4	324602.Caur_0410	3.433e-17	86.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	DUF3404,HATPase_c,HisKA,PAS_8,Response_reg
WH1_k127_1383645_5	172088.AUGA01000039_gene4481	7.885e-11	74.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,3JRSC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
WH1_k127_1383645_2	498761.HM1_2442	1.457e-22	100.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia	186801|Clostridia	FG	PFAM Histidine triad (HIT) protein	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
WH1_k127_1388760_3	383372.Rcas_0376	3.714e-38	148.0	COG0463@1|root,COG0463@2|Bacteria,2G8J3@200795|Chloroflexi,375I8@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH1_k127_1388760_0	926569.ANT_09940	3.668e-72	246.0	COG1403@1|root,COG1403@2|Bacteria,2G6RY@200795|Chloroflexi	200795|Chloroflexi	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
WH1_k127_1388760_1	292459.STH124	5.821e-54	203.0	COG1920@1|root,COG1920@2|Bacteria,1V86Y@1239|Firmicutes,24K51@186801|Clostridia	186801|Clostridia	S	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_1388760_2	926569.ANT_20690	1.097e-47	177.0	COG1544@1|root,COG1544@2|Bacteria,2G6Z4@200795|Chloroflexi	200795|Chloroflexi	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
WH1_k127_1388760_4	926569.ANT_20680	4.714e-34	138.0	COG1040@1|root,COG1040@2|Bacteria,2G6WB@200795|Chloroflexi	200795|Chloroflexi	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
WH1_k127_1390791_0	1487921.DP68_15020	3.177e-132	433.0	COG1228@1|root,COG1228@2|Bacteria,1TVY2@1239|Firmicutes,24D7Q@186801|Clostridia,36H8R@31979|Clostridiaceae	186801|Clostridia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
WH1_k127_1391646_0	530564.Psta_3548	2.409e-46	172.0	COG2062@1|root,COG2062@2|Bacteria,2J0N8@203682|Planctomycetes	203682|Planctomycetes	T	phosphohistidine phosphatase, SixA	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
WH1_k127_1391646_1	926569.ANT_00140	9.368e-40	152.0	COG1959@1|root,COG1959@2|Bacteria,2G8ZH@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
WH1_k127_1391646_2	479434.Sthe_2035	7.578e-33	132.0	COG1651@1|root,COG1651@2|Bacteria,2G8TG@200795|Chloroflexi,27YB4@189775|Thermomicrobia	189775|Thermomicrobia	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
WH1_k127_1391646_3	1121468.AUBR01000001_gene581	6.35e-31	133.0	COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,2489D@186801|Clostridia,42EU4@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
WH1_k127_1425787_0	1121382.JQKG01000054_gene2127	1.21e-24	117.0	COG0823@1|root,COG1357@1|root,COG2374@1|root,COG3209@1|root,COG3210@1|root,COG5492@1|root,COG0823@2|Bacteria,COG1357@2|Bacteria,COG2374@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,1WM95@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	PFAM Endonuclease Exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD
WH1_k127_1425787_1	316274.Haur_1229	1.429e-11	76.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF1080,LVIVD,PKD
WH1_k127_1425787_2	857087.Metme_1782	2.121e-07	63.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,1QXQ3@1224|Proteobacteria,1T3FZ@1236|Gammaproteobacteria,1XFYB@135618|Methylococcales	135618|Methylococcales	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_143315_1	1121378.KB899720_gene234	9.199e-08	63.0	COG1361@1|root,COG4719@1|root,COG1361@2|Bacteria,COG4719@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,FTP,Peptidase_M36,SdrD_B
WH1_k127_143315_0	926569.ANT_12930	4.907e-79	276.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WH1_k127_143315_2	670487.Ocepr_0857	1.154e-05	57.0	COG3743@1|root,COG3743@2|Bacteria	2|Bacteria	S	rRNA binding	rplU	-	-	ko:K02879,ko:K02888,ko:K02890,ko:K02899,ko:K02967,ko:K04074	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03036	-	-	-	HHH_5,Ribosomal_L21p
WH1_k127_1451119_1	1499967.BAYZ01000076_gene800	1.93e-19	94.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K02012,ko:K07114	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	1.A.13.2.2,1.A.13.2.3,3.A.1.10	-	-	SBP_bac_11,VWA,VWA_2,VWA_3
WH1_k127_1451119_0	1499967.BAYZ01000076_gene800	1.599e-114	393.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K02012,ko:K07114	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	1.A.13.2.2,1.A.13.2.3,3.A.1.10	-	-	SBP_bac_11,VWA,VWA_2,VWA_3
WH1_k127_1484676_0	1297742.A176_02025	7.197e-80	274.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,42NCK@68525|delta/epsilon subdivisions,2WMCF@28221|Deltaproteobacteria,2YTU4@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
WH1_k127_1484676_1	1304284.L21TH_1185	9.88e-45	171.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24AFJ@186801|Clostridia,36WRK@31979|Clostridiaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K16210	-	-	-	-	ko00000,ko02000	2.A.2.5	-	-	MFS_2
WH1_k127_1488731_0	1121382.JQKG01000003_gene4233	2.007e-91	315.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM26
WH1_k127_1514242_0	926569.ANT_15210	2.835e-85	293.0	COG0515@1|root,COG0515@2|Bacteria,2G67H@200795|Chloroflexi	200795|Chloroflexi	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WH1_k127_1514242_1	926550.CLDAP_17040	1.864e-37	150.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
WH1_k127_1517340_1	525904.Tter_2774	1.121e-56	204.0	COG4894@1|root,COG4894@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K21429	-	-	-	-	ko00000,ko01002	-	-	-	-
WH1_k127_1517340_0	926569.ANT_16940	2.574e-61	235.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WH1_k127_1517340_2	111780.Sta7437_2496	8.29e-38	146.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,3VIWA@52604|Pleurocapsales	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
WH1_k127_1517852_1	1489678.RDMS_13135	2.486e-06	59.0	COG5658@1|root,COG5658@2|Bacteria	2|Bacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
WH1_k127_1517852_0	720554.Clocl_3342	1.594e-225	717.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3WGF7@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WH1_k127_1520587_3	670487.Ocepr_1935	2.062e-33	142.0	COG0433@1|root,COG1196@1|root,COG0433@2|Bacteria,COG1196@2|Bacteria,1WM64@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_1520587_0	926569.ANT_06210	6.079e-150	496.0	COG2720@1|root,COG2720@2|Bacteria,2G67R@200795|Chloroflexi	200795|Chloroflexi	V	PFAM VanW family protein	-	-	-	-	-	-	-	-	-	-	-	-	G5,PG_binding_4,VanW
WH1_k127_1520587_1	926550.CLDAP_34120	7.733e-57	216.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WH1_k127_1520587_2	1128421.JAGA01000002_gene1319	2.385e-43	180.0	COG1305@1|root,COG1305@2|Bacteria,2NQTS@2323|unclassified Bacteria	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
WH1_k127_1529756_0	1236976.JCM16418_3214	1.396e-45	173.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,26QTA@186822|Paenibacillaceae	91061|Bacilli	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
WH1_k127_1529756_1	365528.KB891208_gene3150	1.09e-06	53.0	COG3339@1|root,COG3339@2|Bacteria,2IMW8@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
WH1_k127_154312_1	485913.Krac_2215	4.907e-79	276.0	COG4552@1|root,COG4552@2|Bacteria,2G7MV@200795|Chloroflexi	200795|Chloroflexi	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
WH1_k127_154312_0	926550.CLDAP_26430	1.417e-85	291.0	COG0388@1|root,COG0388@2|Bacteria,2G6KM@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K11206,ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
WH1_k127_154312_2	1121875.KB907547_gene3443	9.869e-34	135.0	2BWYK@1|root,32R5D@2|Bacteria,4NS4D@976|Bacteroidetes	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4,PAS_8
WH1_k127_1550336_0	926569.ANT_19230	2.571e-33	142.0	COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi	200795|Chloroflexi	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
WH1_k127_1550336_1	405948.SACE_7324	4.526e-11	63.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria,4DZ0E@85010|Pseudonocardiales	201174|Actinobacteria	GT	pyruvate phosphate dikinase	-	-	2.7.9.2	ko:K01007,ko:K21787	ko00333,ko00620,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00333,map00620,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00374,M00837,M00838	R00199,R11662,R11673	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
WH1_k127_1552815_3	251221.35211576	2.485e-12	68.0	COG1178@1|root,COG1178@2|Bacteria,1G1J7@1117|Cyanobacteria	1117|Cyanobacteria	P	ABC-type Fe3 transport system permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
WH1_k127_1552815_1	926569.ANT_29690	1.061e-117	389.0	COG3842@1|root,COG3842@2|Bacteria,2G5P8@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
WH1_k127_1552815_2	926569.ANT_03520	1.473e-30	124.0	COG0640@1|root,COG0640@2|Bacteria,2G980@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WH1_k127_1552815_0	595494.Tola_1002	5.674e-200	631.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1S0YQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
WH1_k127_1561804_2	926569.ANT_17240	2.541e-51	193.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,LysM,PG_binding_1,SH3_3
WH1_k127_1561804_3	1521187.JPIM01000115_gene3357	2.115e-34	136.0	COG2924@1|root,COG2924@2|Bacteria,2G6XQ@200795|Chloroflexi,377PE@32061|Chloroflexia	32061|Chloroflexia	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
WH1_k127_1561804_0	326427.Cagg_2251	1.429e-135	443.0	COG0151@1|root,COG0151@2|Bacteria,2G7M4@200795|Chloroflexi,377MJ@32061|Chloroflexia	32061|Chloroflexia	F	ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
WH1_k127_1561804_1	926569.ANT_12990	1.046e-93	325.0	COG2367@1|root,COG2367@2|Bacteria,2G75H@200795|Chloroflexi	200795|Chloroflexi	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
WH1_k127_1575201_0	926569.ANT_14870	6.447e-156	502.0	COG0112@1|root,COG0404@1|root,COG0112@2|Bacteria,COG0404@2|Bacteria,2G624@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
WH1_k127_1575201_1	192952.MM_1377	3.825e-43	170.0	COG5607@1|root,arCOG05139@2157|Archaea,2Y7EP@28890|Euryarchaeota,2NA8G@224756|Methanomicrobia	224756|Methanomicrobia	F	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
WH1_k127_1598173_1	411489.CLOL250_00199	3.919e-16	87.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia,36I2X@31979|Clostridiaceae	186801|Clostridia	H	SMART Metal-dependent phosphohydrolase, HD region	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
WH1_k127_1598173_0	326427.Cagg_1901	3.631e-99	334.0	COG0624@1|root,COG0624@2|Bacteria,2G63E@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WH1_k127_1608757_1	326427.Cagg_3389	1.602e-21	95.0	COG2379@1|root,COG2379@2|Bacteria,2G5RZ@200795|Chloroflexi,374XG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM MOFRL domain protein	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
WH1_k127_1608757_0	926569.ANT_31260	3.74e-225	707.0	COG1109@1|root,COG1109@2|Bacteria,2G5PR@200795|Chloroflexi	200795|Chloroflexi	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WH1_k127_1615140_1	926569.ANT_17930	9.284e-51	182.0	COG0822@1|root,COG0822@2|Bacteria,2G71H@200795|Chloroflexi	200795|Chloroflexi	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
WH1_k127_1615140_2	926569.ANT_17920	7.974e-32	129.0	COG2146@1|root,COG2146@2|Bacteria,2G7AG@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
WH1_k127_1615140_0	518766.Rmar_1222	3.521e-203	653.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1FJ26@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WH1_k127_1615140_3	314230.DSM3645_13525	5.121e-22	100.0	COG0156@1|root,COG0318@1|root,COG0156@2|Bacteria,COG0318@2|Bacteria,2IXBN@203682|Planctomycetes	203682|Planctomycetes	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
WH1_k127_1616893_1	937777.Deipe_2178	2.032e-10	72.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771,ko:K08372	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,PG_binding_1,Trypsin_2
WH1_k127_1616893_0	661478.OP10G_1971	7.423e-62	237.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_161767_2	404589.Anae109_0136	4.913e-06	56.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MVME@1224|Proteobacteria,43AKG@68525|delta/epsilon subdivisions,2X60I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF
WH1_k127_161767_3	329726.AM1_2178	1.923e-05	57.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
WH1_k127_161767_0	1318628.MARLIPOL_09446	3.65e-35	136.0	COG4737@1|root,COG4737@2|Bacteria,1N7N5@1224|Proteobacteria,1S6BG@1236|Gammaproteobacteria,46BS7@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	RelE toxin of RelE / RelB toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
WH1_k127_161767_1	153948.NAL212_2452	1.351e-13	73.0	COG2944@1|root,COG2944@2|Bacteria,1N5H0@1224|Proteobacteria,2VW7F@28216|Betaproteobacteria,373DX@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Helix-turn-helix domain	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31,MqsA_antitoxin
WH1_k127_164428_1	765420.OSCT_1373	8.817e-25	109.0	COG2931@1|root,COG2931@2|Bacteria,2GBI9@200795|Chloroflexi,377IY@32061|Chloroflexia	32061|Chloroflexia	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
WH1_k127_164428_0	765420.OSCT_2114	4.019e-70	250.0	COG2931@1|root,COG2931@2|Bacteria,2GBI9@200795|Chloroflexi,377IY@32061|Chloroflexia	32061|Chloroflexia	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
WH1_k127_164872_2	383372.Rcas_0730	6.571e-08	61.0	COG5662@1|root,COG5662@2|Bacteria,2G9S9@200795|Chloroflexi,375WU@32061|Chloroflexia	32061|Chloroflexia	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_164872_0	765420.OSCT_2500	1.257e-57	210.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi,375K5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH1_k127_164872_1	7245.FBpp0260894	9.225e-09	57.0	2D82N@1|root,2T8G1@2759|Eukaryota,3930P@33154|Opisthokonta,3C8AX@33208|Metazoa,3DPBM@33213|Bilateria,425JT@6656|Arthropoda,3SV54@50557|Insecta,4587U@7147|Diptera,45Z7T@7214|Drosophilidae	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_1657557_2	1463895.JODA01000016_gene6427	1.335e-06	53.0	2EIY5@1|root,33CPB@2|Bacteria,2I391@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_1657557_1	1050202.KB913024_gene970	1.027e-22	106.0	COG3502@1|root,COG3542@1|root,COG3502@2|Bacteria,COG3542@2|Bacteria,2IFG5@201174|Actinobacteria,4080G@622450|Actinopolysporales	201174|Actinobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5,DUF952
WH1_k127_1657557_0	926569.ANT_15050	7.237e-28	116.0	COG0805@1|root,COG0805@2|Bacteria,2G6SP@200795|Chloroflexi	200795|Chloroflexi	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
WH1_k127_1665239_1	1128421.JAGA01000002_gene1941	3.358e-23	112.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
WH1_k127_1665239_0	926569.ANT_14320	1.761e-36	142.0	COG0818@1|root,COG0818@2|Bacteria,2G75I@200795|Chloroflexi	200795|Chloroflexi	M	PFAM diacylglycerol kinase	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
WH1_k127_1665239_2	867845.KI911784_gene317	1.379e-15	80.0	COG2267@1|root,COG2267@2|Bacteria,2GAN0@200795|Chloroflexi,376T9@32061|Chloroflexia	32061|Chloroflexia	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WH1_k127_1667914_2	926569.ANT_13160	3.77e-40	162.0	COG1664@1|root,COG1664@2|Bacteria,2G7EZ@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
WH1_k127_1667914_0	926550.CLDAP_19720	1.231e-180	576.0	COG0174@1|root,COG0174@2|Bacteria,2G5U2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM glutamine synthetase catalytic region	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
WH1_k127_1667914_1	1499967.BAYZ01000073_gene2042	2.172e-42	165.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,2NP16@2323|unclassified Bacteria	2|Bacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GAF,GAF_2,Guanylate_cyc,HATPase_c,HisKA,PAS,PAS_4,Response_reg,SpoIIE
WH1_k127_168492_2	765420.OSCT_1747	1.993e-12	73.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,376VY@32061|Chloroflexia	32061|Chloroflexia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
WH1_k127_168492_0	391625.PPSIR1_13410	9.184e-25	107.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,42V8V@68525|delta/epsilon subdivisions,2WRKG@28221|Deltaproteobacteria,2Z1JK@29|Myxococcales	28221|Deltaproteobacteria	C	acylphosphatase activity	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
WH1_k127_168492_1	926550.CLDAP_15770	2.183e-24	117.0	2EPQX@1|root,33HBF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_1703033_0	485913.Krac_2635	6.088e-136	449.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
WH1_k127_1703033_1	357808.RoseRS_4134	1.78e-83	287.0	COG1612@1|root,COG1612@2|Bacteria,2G75U@200795|Chloroflexi,376ZK@32061|Chloroflexia	32061|Chloroflexia	O	PFAM cytochrome oxidase assembly	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
WH1_k127_1712951_2	77635.BISU_1239	6.337e-46	177.0	COG0619@1|root,COG0619@2|Bacteria,2GM93@201174|Actinobacteria,4CZXW@85004|Bifidobacteriales	201174|Actinobacteria	P	Cobalt transport protein	cbiQ	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
WH1_k127_1712951_1	926550.CLDAP_23290	2.595e-201	645.0	COG1132@1|root,COG1132@2|Bacteria,2G7J5@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WH1_k127_1712951_0	926550.CLDAP_11260	3.678e-221	702.0	COG1132@1|root,COG1132@2|Bacteria,2G7QN@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
WH1_k127_1712951_3	1121861.KB899916_gene1696	5.548e-06	51.0	2DI7R@1|root,3029U@2|Bacteria,1NC8C@1224|Proteobacteria,2UHZR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_171305_2	370438.PTH_1451	3.277e-23	105.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,2612R@186807|Peptococcaceae	186801|Clostridia	U	type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
WH1_k127_171305_1	765420.OSCT_3196	3.248e-59	223.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
WH1_k127_171305_0	316274.Haur_3362	1.939e-105	349.0	COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi,37550@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WH1_k127_171469_0	1038858.AXBA01000030_gene2919	9.766e-15	89.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1RFJR@1224|Proteobacteria,2U8FI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Hint_2
WH1_k127_171596_0	469383.Cwoe_5282	1.977e-184	591.0	COG2317@1|root,COG2317@2|Bacteria,2IACE@201174|Actinobacteria,4CPDZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
WH1_k127_171596_1	1174528.JH992898_gene4277	7.452e-30	132.0	COG1262@1|root,COG1672@1|root,COG1262@2|Bacteria,COG1672@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	AAA_16,FGE-sulfatase,VPEP
WH1_k127_1738967_1	379066.GAU_2768	1.368e-61	218.0	COG0205@1|root,COG0205@2|Bacteria,1ZTAR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
WH1_k127_1738967_0	472759.Nhal_2967	4.187e-90	309.0	COG0309@1|root,COG0309@2|Bacteria,1N04A@1224|Proteobacteria,1SK12@1236|Gammaproteobacteria,1X0HN@135613|Chromatiales	135613|Chromatiales	O	PFAM AIR synthase related protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AIRS,AIRS_C
WH1_k127_1738967_2	926550.CLDAP_04710	2.46e-21	99.0	COG2182@1|root,COG2182@2|Bacteria,2G91A@200795|Chloroflexi	200795|Chloroflexi	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
WH1_k127_1741088_1	1144275.COCOR_02900	3.331e-14	80.0	COG3940@1|root,COG3940@2|Bacteria	2|Bacteria	G	arabinan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
WH1_k127_1741088_0	1134912.AJTV01000021_gene3004	2.267e-157	521.0	COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,2U2CB@28211|Alphaproteobacteria,36YRU@31993|Methylocystaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
WH1_k127_1749744_2	1500306.JQLA01000006_gene726	3.466e-29	126.0	COG4608@1|root,COG4608@2|Bacteria,1R3RB@1224|Proteobacteria,2TTSS@28211|Alphaproteobacteria,4B7J3@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
WH1_k127_1749744_1	1128421.JAGA01000002_gene1099	1.614e-42	165.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	M1-584	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
WH1_k127_1749744_0	926569.ANT_28060	7.231e-106	351.0	COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
WH1_k127_1769738_1	926569.ANT_26430	1.167e-31	143.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2G6IW@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH1_k127_1769738_0	765869.BDW_03880	5.279e-39	153.0	COG2114@1|root,COG2770@1|root,COG2114@2|Bacteria,COG2770@2|Bacteria,1MV1V@1224|Proteobacteria,42SUQ@68525|delta/epsilon subdivisions,2MUNS@213481|Bdellovibrionales,2WPIY@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
WH1_k127_1774013_1	521098.Aaci_0157	6.69e-43	167.0	COG1028@1|root,COG1028@2|Bacteria,1UETI@1239|Firmicutes,4HB6V@91061|Bacilli,279MG@186823|Alicyclobacillaceae	91061|Bacilli	IQ	PFAM short-chain dehydrogenase reductase SDR	fabG_4	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
WH1_k127_1774013_0	926569.ANT_27830	4.125e-90	315.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
WH1_k127_1774013_2	748658.KB907314_gene191	2.215e-20	93.0	COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,1S94C@1236|Gammaproteobacteria,1WYZS@135613|Chromatiales	135613|Chromatiales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WH1_k127_1806948_2	926569.ANT_03760	1.502e-14	73.0	COG2018@1|root,COG2018@2|Bacteria,2G8WW@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
WH1_k127_1806948_1	926569.ANT_03770	7.703e-90	300.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi	200795|Chloroflexi	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
WH1_k127_1806948_0	926550.CLDAP_11790	1.071e-116	400.0	COG2244@1|root,COG4485@1|root,COG2244@2|Bacteria,COG4485@2|Bacteria,2G6CM@200795|Chloroflexi	200795|Chloroflexi	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
WH1_k127_1809068_0	1487953.JMKF01000043_gene2591	7.143e-103	349.0	COG5542@1|root,COG5542@2|Bacteria	2|Bacteria	O	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2,PMT_2
WH1_k127_1815474_1	383372.Rcas_3770	6.627e-87	306.0	COG1819@1|root,COG1819@2|Bacteria,2G865@200795|Chloroflexi,375NW@32061|Chloroflexia	32061|Chloroflexia	CG	PFAM glycosyl transferase, family 28	-	-	2.4.1.173	ko:K05841	-	-	-	-	ko00000,ko01000,ko01003	-	GT1	-	Glyco_transf_28,UDPGT
WH1_k127_1815474_2	357808.RoseRS_4278	5.635e-52	199.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0044237,GO:0044249	2.1.1.254,2.1.1.295,2.1.1.79,2.7.11.1	ko:K00574,ko:K07154,ko:K14369,ko:K15257,ko:K18534	ko00130,ko00522,ko01100,ko01110,ko01130,map00130,map00522,map01100,map01110,map01130	M00112,M00774	R05520,R05532,R07501,R10709,R10710	RC00003,RC01324,RC01662	ko00000,ko00001,ko00002,ko01000,ko01001,ko01008,ko02048,ko03016	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
WH1_k127_1815474_4	1033810.HLPCO_002949	7.2e-07	59.0	COG2128@1|root,COG2128@2|Bacteria,2NS09@2323|unclassified Bacteria	2|Bacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WH1_k127_1815474_3	1293054.HSACCH_00450	6.607e-16	81.0	COG2128@1|root,COG2128@2|Bacteria,1UVG3@1239|Firmicutes	1239|Firmicutes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WH1_k127_1815474_0	926550.CLDAP_39030	1.962e-192	630.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
WH1_k127_1815474_5	269797.Mbar_A2106	0.000273	52.0	arCOG03606@1|root,arCOG03606@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Collagen,PKD,S_layer_C
WH1_k127_1848027_0	316274.Haur_1458	2.988e-120	401.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3766E@32061|Chloroflexia	32061|Chloroflexia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
WH1_k127_18605_0	756067.MicvaDRAFT_1840	3.01e-209	677.0	COG1672@1|root,COG1672@2|Bacteria,1G4AU@1117|Cyanobacteria,1HAF9@1150|Oscillatoriales	1117|Cyanobacteria	S	Pfam:Arch_ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
WH1_k127_1861587_2	1287116.X734_10275	7.439e-51	185.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TRRH@28211|Alphaproteobacteria,43JHB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	BQ	including yeast histone deacetylase and acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
WH1_k127_1861587_0	926550.CLDAP_36880	1.094e-129	424.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
WH1_k127_1861587_1	357808.RoseRS_1213	1.431e-107	353.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,2G5M1@200795|Chloroflexi,376VN@32061|Chloroflexia	32061|Chloroflexia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
WH1_k127_1872227_0	671143.DAMO_2345	3.442e-91	304.0	COG0451@1|root,COG0451@2|Bacteria,2NNT0@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	lspL	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
WH1_k127_1872227_1	383372.Rcas_4176	8.059e-57	202.0	COG0500@1|root,COG2226@2|Bacteria,2GBRI@200795|Chloroflexi,3769K@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WH1_k127_1908234_0	215803.DB30_8640	1.052e-175	565.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,43AER@68525|delta/epsilon subdivisions,2X5UG@28221|Deltaproteobacteria,2YUH1@29|Myxococcales	28221|Deltaproteobacteria	M	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,NHL,RHS_repeat
WH1_k127_1922532_1	926550.CLDAP_11310	3.781e-88	303.0	COG0559@1|root,COG0559@2|Bacteria,2G6FM@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WH1_k127_1922532_0	926550.CLDAP_11320	4.649e-151	488.0	COG0683@1|root,COG0683@2|Bacteria,2G6Q3@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WH1_k127_1933294_0	56110.Oscil6304_3528	2.28e-120	395.0	COG0451@1|root,COG0451@2|Bacteria,1G0QH@1117|Cyanobacteria,1H7R6@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM NAD dependent epimerase dehydratase family	-	-	4.1.1.35,5.1.3.2	ko:K01784,ko:K08678	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01384,R02984	RC00289,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WH1_k127_1933294_1	886293.Sinac_4732	7.448e-58	212.0	COG1215@1|root,COG1215@2|Bacteria,2J0E2@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH1_k127_1933294_2	1385519.N801_12865	7.758e-15	76.0	COG0451@1|root,COG0451@2|Bacteria,2GK8K@201174|Actinobacteria,4FGXM@85021|Intrasporangiaceae	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2,5.1.3.25	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	M00361,M00362,M00632	R00291,R02984,R10279	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
WH1_k127_1938014_3	1128421.JAGA01000002_gene1522	6.565e-76	256.0	COG0451@1|root,COG0451@2|Bacteria,2NQVT@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	-	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784,ko:K13318,ko:K13322,ko:K16439,ko:K19857	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793,M00798,M00799,M00800	R00291,R02984,R06436,R06513,R06629,R11042,R11047	RC00182,RC00261,RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
WH1_k127_1938014_4	1173023.KE650771_gene1099	2.13e-51	185.0	COG1403@1|root,COG1403@2|Bacteria,1G7ZB@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
WH1_k127_1938014_5	1173027.Mic7113_0165	5.544e-38	149.0	2E16Z@1|root,31VE4@2|Bacteria,1G7HJ@1117|Cyanobacteria,1HCJY@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_1938014_1	926569.ANT_07490	2.004e-81	279.0	COG0600@1|root,COG0600@2|Bacteria,2G6HW@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
WH1_k127_1938014_0	926569.ANT_07480	1.407e-94	323.0	COG0715@1|root,COG0715@2|Bacteria,2G6E9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
WH1_k127_1938014_2	926569.ANT_07470	1.038e-78	273.0	COG1116@1|root,COG1116@2|Bacteria,2G8C7@200795|Chloroflexi	200795|Chloroflexi	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
WH1_k127_1938014_6	585423.KR49_10375	4.443e-05	53.0	COG3307@1|root,COG3307@2|Bacteria,1G1ZH@1117|Cyanobacteria,1GZSF@1129|Synechococcus	1117|Cyanobacteria	M	COG3307 Lipid A core - O-antigen ligase and related enzymes	ictB	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
WH1_k127_1953007_0	926569.ANT_09410	1.204e-62	225.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WH1_k127_1953007_1	926569.ANT_09400	1.002e-19	94.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	-	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
WH1_k127_1954787_0	1007103.AFHW01000087_gene6320	3.72e-144	463.0	COG0179@1|root,COG0179@2|Bacteria,1VRIW@1239|Firmicutes,4HUFK@91061|Bacilli,26U89@186822|Paenibacillaceae	91061|Bacilli	Q	Fumarylacetoacetase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase,FAA_hydrolase_N
WH1_k127_1958710_0	926569.ANT_15910	5.426e-156	497.0	COG0481@1|root,COG0481@2|Bacteria,2G5K2@200795|Chloroflexi	200795|Chloroflexi	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
WH1_k127_1958710_1	1487953.JMKF01000005_gene598	1.094e-36	141.0	COG1232@1|root,COG1232@2|Bacteria,1G05M@1117|Cyanobacteria,1H8M6@1150|Oscillatoriales	1117|Cyanobacteria	H	Protoporphyrinogen oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
WH1_k127_1961635_3	926569.ANT_14810	9.446e-63	224.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
WH1_k127_1961635_0	5039.XP_002622471.1	1.192e-163	559.0	COG0520@1|root,KOG2142@2759|Eukaryota,38F30@33154|Opisthokonta,3NY5Z@4751|Fungi,3QREF@4890|Ascomycota,20FDX@147545|Eurotiomycetes,3B2AK@33183|Onygenales	4751|Fungi	H	Molybdenum cofactor sulfurase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WH1_k127_1961635_1	926569.ANT_14390	2.005e-152	525.0	COG0402@1|root,COG0402@2|Bacteria,2G7M9@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WH1_k127_1961635_2	926569.ANT_14400	8.523e-75	257.0	COG2085@1|root,COG2085@2|Bacteria,2G7DD@200795|Chloroflexi	200795|Chloroflexi	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
WH1_k127_1961635_4	502025.Hoch_0061	2.827e-38	148.0	COG1478@1|root,COG1478@2|Bacteria,1PQHN@1224|Proteobacteria,4324K@68525|delta/epsilon subdivisions,2WY50@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.12,6.3.2.17,6.3.2.31,6.3.2.34	ko:K12234,ko:K22099	ko00680,ko00790,ko01120,map00680,map00790,map01120	M00378,M00840	R00942,R02237,R04241,R09399,R09400	RC00064,RC00090,RC00141,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
WH1_k127_1965247_0	926550.CLDAP_06970	2.617e-93	308.0	COG0589@1|root,COG1215@1|root,COG0589@2|Bacteria,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266,2.4.1.268	ko:K09118,ko:K13693,ko:K21349	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2,Usp
WH1_k127_1965247_1	926550.CLDAP_06980	2.671e-53	201.0	COG0406@1|root,COG0406@2|Bacteria,2G731@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
WH1_k127_1965247_2	1246995.AFR_38645	5.511e-10	60.0	COG0122@1|root,COG0122@2|Bacteria,2IPPK@201174|Actinobacteria	201174|Actinobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
WH1_k127_19674_2	357808.RoseRS_0354	4.093e-12	72.0	COG0747@1|root,COG0747@2|Bacteria,2G5KD@200795|Chloroflexi,3768F@32061|Chloroflexia	2|Bacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	B_lectin,PA,SBP_bac_5
WH1_k127_19674_0	926550.CLDAP_33840	5.823e-115	380.0	COG1313@1|root,COG1313@2|Bacteria,2G65I@200795|Chloroflexi	200795|Chloroflexi	C	Radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WH1_k127_19674_1	1121430.JMLG01000001_gene2310	8.29e-57	209.0	COG3634@1|root,COG3634@2|Bacteria,1UIUB@1239|Firmicutes,25ES4@186801|Clostridia,267GT@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Glutaredoxin,Pyr_redox_2,Thioredoxin_3
WH1_k127_1974841_0	926569.ANT_08030	4.993e-18	99.0	COG1361@1|root,COG3764@1|root,COG1361@2|Bacteria,COG3764@2|Bacteria,2G854@200795|Chloroflexi	200795|Chloroflexi	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
WH1_k127_198076_2	926569.ANT_25090	1.408e-59	221.0	COG4942@1|root,COG4942@2|Bacteria,2G960@200795|Chloroflexi	200795|Chloroflexi	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_198076_0	926550.CLDAP_29930	1.907e-81	284.0	COG0438@1|root,COG0438@2|Bacteria,2G82Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH1_k127_198076_1	926550.CLDAP_29920	1.729e-67	243.0	COG0438@1|root,COG0438@2|Bacteria,2G6I1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
WH1_k127_1990827_1	489825.LYNGBM3L_30250	6.27e-40	153.0	COG0604@1|root,COG0604@2|Bacteria,1G0N4@1117|Cyanobacteria,1H9U9@1150|Oscillatoriales	1117|Cyanobacteria	C	NADPH quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
WH1_k127_1990827_0	926569.ANT_02540	5.942e-69	247.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
WH1_k127_1991905_0	926569.ANT_11300	2.295e-155	508.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WH1_k127_1991905_3	926569.ANT_11310	9.096e-18	85.0	COG1314@1|root,COG1314@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
WH1_k127_1991905_1	926569.ANT_15200	2.577e-126	413.0	COG0387@1|root,COG0387@2|Bacteria,2G6GE@200795|Chloroflexi	200795|Chloroflexi	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
WH1_k127_1991905_2	926550.CLDAP_17040	2.991e-24	109.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
WH1_k127_1993816_0	1121877.JQKF01000031_gene2060	1.298e-11	78.0	COG4932@1|root,COG4932@2|Bacteria,2HFKJ@201174|Actinobacteria,4CNFG@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
WH1_k127_1993816_1	1121378.KB899700_gene1980	4.722e-10	73.0	COG0515@1|root,COG1470@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	3.2.1.50	ko:K01205,ko:K07004	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078	R07816	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ChW,DUF916,NAGLU,NAGLU_C,NAGLU_N,Ricin_B_lectin
WH1_k127_2027015_0	324602.Caur_0080	1.613e-148	482.0	COG1345@1|root,COG1572@1|root,COG1345@2|Bacteria,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	ko:K02396,ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	-
WH1_k127_2027015_1	926550.CLDAP_38410	1.545e-47	181.0	COG2120@1|root,COG2120@2|Bacteria,2G6YU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WH1_k127_2027015_2	926569.ANT_29880	2.576e-46	180.0	COG0782@1|root,COG0782@2|Bacteria,2G6U9@200795|Chloroflexi	200795|Chloroflexi	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
WH1_k127_2027015_3	926569.ANT_29890	5.263e-27	115.0	COG1190@1|root,COG1190@2|Bacteria,2G65Z@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WH1_k127_2050549_0	926550.CLDAP_01030	4.766e-48	185.0	COG2068@1|root,COG2068@2|Bacteria,2G6W9@200795|Chloroflexi	200795|Chloroflexi	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
WH1_k127_2086144_0	926550.CLDAP_17660	3.528e-28	130.0	COG2308@1|root,COG2308@2|Bacteria,2G7ZB@200795|Chloroflexi	200795|Chloroflexi	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
WH1_k127_2086144_1	190650.CC_2824	4.968e-05	51.0	COG0312@1|root,COG0312@2|Bacteria,1QM7I@1224|Proteobacteria,2V4PD@28211|Alphaproteobacteria,2KG8P@204458|Caulobacterales	204458|Caulobacterales	L	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
WH1_k127_2087507_0	926569.ANT_28270	2.356e-17	83.0	2DFYG@1|root,2ZTRA@2|Bacteria,2G9KK@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
WH1_k127_2087507_1	43354.JOIJ01000002_gene4390	3.913e-11	71.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4E16P@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the peptidase M16 family	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WH1_k127_21193_1	1128421.JAGA01000003_gene3596	1.247e-32	127.0	COG0745@1|root,COG0745@2|Bacteria,2NR2D@2323|unclassified Bacteria	2|Bacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WH1_k127_21193_0	326427.Cagg_1372	1.875e-102	342.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,37579@32061|Chloroflexia	32061|Chloroflexia	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WH1_k127_2120889_1	926569.ANT_00170	1.695e-62	218.0	COG0177@1|root,COG0177@2|Bacteria,2G6QA@200795|Chloroflexi	200795|Chloroflexi	L	FES	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
WH1_k127_2120889_0	926569.ANT_25700	1.119e-117	399.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
WH1_k127_2148551_0	1174528.JH992890_gene467	1.48e-33	145.0	COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria	2|Bacteria	Q	synthase	-	-	-	ko:K15314	ko01059,ko01130,map01059,map01130	M00824,M00825	R11435	-	ko00000,ko00001,ko00002,ko01008	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
WH1_k127_2158572_0	926550.CLDAP_11300	8.506e-128	421.0	COG4177@1|root,COG4177@2|Bacteria,2G6D8@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WH1_k127_2158572_1	357808.RoseRS_2976	1.094e-31	125.0	COG0559@1|root,COG0559@2|Bacteria,2G6FM@200795|Chloroflexi,375K9@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WH1_k127_2166862_1	357808.RoseRS_1080	2.729e-83	284.0	COG2326@1|root,COG2326@2|Bacteria,2G5UP@200795|Chloroflexi,37688@32061|Chloroflexia	32061|Chloroflexia	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
WH1_k127_2166862_0	383372.Rcas_2786	9.967e-105	349.0	COG2326@1|root,COG2326@2|Bacteria,2G5UP@200795|Chloroflexi,37688@32061|Chloroflexia	32061|Chloroflexia	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
WH1_k127_2166862_3	378806.STAUR_3873	2.145e-51	201.0	COG2267@1|root,COG2267@2|Bacteria,1RFE1@1224|Proteobacteria,42UMK@68525|delta/epsilon subdivisions,2WQNF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
WH1_k127_2166862_2	926569.ANT_02010	3.645e-80	268.0	COG2057@1|root,COG2057@2|Bacteria,2G6MS@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WH1_k127_2177970_0	867845.KI911784_gene1111	1.783e-132	437.0	COG2211@1|root,COG2211@2|Bacteria,2G6RZ@200795|Chloroflexi	200795|Chloroflexi	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WH1_k127_2177970_1	324602.Caur_0433	3.28e-114	376.0	COG2141@1|root,COG2141@2|Bacteria,2G5MF@200795|Chloroflexi,376CU@32061|Chloroflexia	32061|Chloroflexia	C	PFAM luciferase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
WH1_k127_2177970_4	1121456.ATVA01000013_gene1125	3.335e-25	113.0	COG4392@1|root,COG4392@2|Bacteria,1NH6U@1224|Proteobacteria,437B5@68525|delta/epsilon subdivisions,2X2FW@28221|Deltaproteobacteria,2MDB6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
WH1_k127_2177970_2	485913.Krac_5262	2.007e-73	254.0	COG1296@1|root,COG1296@2|Bacteria,2G6SG@200795|Chloroflexi	200795|Chloroflexi	E	PFAM AzlC family protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
WH1_k127_2177970_3	370438.PTH_1451	5.788e-51	188.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,2612R@186807|Peptococcaceae	186801|Clostridia	U	type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
WH1_k127_2181576_1	404589.Anae109_0573	2.116e-129	418.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2WJG7@28221|Deltaproteobacteria,2YUAP@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
WH1_k127_2181576_0	926569.ANT_05830	1.132e-168	536.0	COG1883@1|root,COG1883@2|Bacteria	2|Bacteria	C	oxaloacetate decarboxylase activity	oadB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
WH1_k127_2181576_2	926569.ANT_05820	1.788e-30	125.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	gcdC	-	2.1.3.1,4.1.1.70,6.4.1.3	ko:K01615,ko:K01965,ko:K02160,ko:K17490	ko00061,ko00280,ko00362,ko00620,ko00630,ko00640,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00362,map00620,map00630,map00640,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00353,R00742,R01859,R03028	RC00040,RC00097,RC00367,RC00609,RC00832	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.3	-	-	Biotin_lipoyl
WH1_k127_2202503_1	765420.OSCT_1671	1.112e-08	60.0	COG0500@1|root,COG2226@2|Bacteria,2GB34@200795|Chloroflexi,3778K@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WH1_k127_2206014_0	997346.HMPREF9374_1437	6.592e-208	659.0	COG1506@1|root,COG1506@2|Bacteria,1TQ85@1239|Firmicutes,4HAC0@91061|Bacilli	91061|Bacilli	EU	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
WH1_k127_2211756_2	330214.NIDE0660	6.766e-45	166.0	COG1373@1|root,COG1373@2|Bacteria,3J14P@40117|Nitrospirae	40117|Nitrospirae	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WH1_k127_2211756_0	926569.ANT_10740	6.969e-204	660.0	COG2304@1|root,COG2304@2|Bacteria,2G7VX@200795|Chloroflexi	200795|Chloroflexi	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA
WH1_k127_2211756_1	1519464.HY22_13745	1.714e-94	318.0	COG0618@1|root,COG0618@2|Bacteria,1FEID@1090|Chlorobi	1090|Chlorobi	S	3'(2'),5'-bisphosphate nucleotidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_2218237_0	926569.ANT_28730	2.571e-68	239.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2G68T@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WH1_k127_2220603_1	926569.ANT_23420	1.428e-101	339.0	COG0812@1|root,COG0812@2|Bacteria,2G6H3@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
WH1_k127_2220603_0	383372.Rcas_1090	2.592e-120	397.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,3750N@32061|Chloroflexia	32061|Chloroflexia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
WH1_k127_2220603_3	479434.Sthe_1989	2.28e-09	68.0	COG1589@1|root,COG1589@2|Bacteria,2G7FV@200795|Chloroflexi,27YKW@189775|Thermomicrobia	189775|Thermomicrobia	D	POTRA domain, FtsQ-type	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
WH1_k127_2220603_2	926569.ANT_23450	7.155e-32	126.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
WH1_k127_2228216_0	1173028.ANKO01000042_gene858	9.628e-263	830.0	COG2366@1|root,COG2366@2|Bacteria,1G4M5@1117|Cyanobacteria	1117|Cyanobacteria	S	penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
WH1_k127_2240890_4	56107.Cylst_0166	8.566e-10	63.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G2R4@1117|Cyanobacteria,1HMFH@1161|Nostocales	1117|Cyanobacteria	CT	PBS lyase	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
WH1_k127_2240890_2	926569.ANT_23620	5.068e-20	98.0	COG2839@1|root,COG2839@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF456)	yqgC	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
WH1_k127_2240890_0	1128421.JAGA01000002_gene397	1.214e-170	547.0	COG0172@1|root,COG0172@2|Bacteria,2NNRH@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0000049,GO:0000166,GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016020,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046983,GO:0070905,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528,iSDY_1059.SDY_2368	Seryl_tRNA_N,tRNA-synt_2b
WH1_k127_2240890_1	926569.ANT_29890	1.241e-62	216.0	COG1190@1|root,COG1190@2|Bacteria,2G65Z@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WH1_k127_224317_0	926569.ANT_14840	2.513e-222	703.0	COG2414@1|root,COG2414@2|Bacteria	2|Bacteria	C	aldehyde ferredoxin oxidoreductase activity	-	-	1.2.7.5,1.2.7.6	ko:K03738,ko:K11389	ko00010,ko00030,ko01100,ko01120,ko01200,ko01230,map00010,map00030,map01100,map01120,map01200,map01230	M00001,M00002,M00309	R07159,R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WH1_k127_224317_1	580327.Tthe_0478	3.16e-21	105.0	COG1388@1|root,COG1388@2|Bacteria,1UHZC@1239|Firmicutes,25E80@186801|Clostridia,42FCR@68295|Thermoanaerobacterales	186801|Clostridia	M	Peptidoglycan-binding lysin domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1
WH1_k127_2251370_2	1382356.JQMP01000003_gene1592	1.093e-09	60.0	COG0714@1|root,COG0714@2|Bacteria,2G669@200795|Chloroflexi,27YUB@189775|Thermomicrobia	189775|Thermomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WH1_k127_2251370_0	357808.RoseRS_0586	1.844e-81	285.0	COG1721@1|root,COG1721@2|Bacteria,2G6Y7@200795|Chloroflexi,3773W@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WH1_k127_2251370_1	357808.RoseRS_0867	1.224e-23	118.0	2A4PD@1|root,30TAH@2|Bacteria,2GB7S@200795|Chloroflexi,377IM@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
WH1_k127_2255037_0	383372.Rcas_1589	2.847e-83	284.0	COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi,376AB@32061|Chloroflexia	32061|Chloroflexia	P	ABC-3 protein	-	-	-	ko:K09819	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
WH1_k127_2255037_2	383372.Rcas_1590	5.437e-68	248.0	COG1121@1|root,COG1121@2|Bacteria,2G7X2@200795|Chloroflexi,377ZC@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter related	-	-	-	ko:K09820	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
WH1_k127_2255037_1	765420.OSCT_1918	2.693e-74	267.0	COG0803@1|root,COG0803@2|Bacteria,2G8F6@200795|Chloroflexi,37738@32061|Chloroflexia	32061|Chloroflexia	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K02077,ko:K09818	-	M00243,M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
WH1_k127_2255037_3	926569.ANT_20950	4.482e-26	113.0	COG0735@1|root,COG0735@2|Bacteria,2G74Y@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
WH1_k127_226110_1	525904.Tter_0301	4.162e-45	176.0	COG2203@1|root,COG3284@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3284@2|Bacteria,COG4585@2|Bacteria,2NPMD@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07777,ko:K19661,ko:K21405	ko02020,map02020	M00478,M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,HATPase_c,HisKA,HisKA_3,Lactamase_B_2,PAS,PAS_4,PAS_9
WH1_k127_226110_0	926569.ANT_17720	7.301e-60	209.0	COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi	200795|Chloroflexi	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
WH1_k127_2271080_2	926569.ANT_22610	6.495e-59	208.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
WH1_k127_2271080_0	926569.ANT_22600	1.547e-120	397.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
WH1_k127_2271080_1	768671.ThimaDRAFT_1778	5.992e-100	336.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,1X0CX@135613|Chromatiales	135613|Chromatiales	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.25	ko:K17950	ko00270,map00270	-	R07634	RC01784	ko00000,ko00001,ko01000	-	-	-	PALP
WH1_k127_2276677_2	383372.Rcas_0848	7.265e-18	86.0	COG1752@1|root,COG1752@2|Bacteria,2GAAT@200795|Chloroflexi,374T8@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
WH1_k127_2276677_0	383372.Rcas_3773	6.13e-167	537.0	COG0427@1|root,COG0427@2|Bacteria,2G60V@200795|Chloroflexi,376DI@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acetyl-CoA hydrolase transferase	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
WH1_k127_2276677_1	1123368.AUIS01000007_gene2814	1.838e-58	209.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
WH1_k127_2278331_1	926550.CLDAP_27570	1.682e-21	94.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH1_k127_2278331_0	1382306.JNIM01000001_gene4027	1.749e-82	283.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WH1_k127_2301557_1	667014.Thein_1829	2.147e-05	56.0	COG0330@1|root,COG0330@2|Bacteria,2GHBQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WH1_k127_2306262_2	1128421.JAGA01000002_gene1845	2.265e-11	64.0	COG0623@1|root,COG0623@2|Bacteria	2|Bacteria	I	enoyl-[acyl-carrier-protein] reductase (NADH) activity	fabI	GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WH1_k127_2306262_1	926569.ANT_08510	1.743e-56	205.0	COG2094@1|root,COG2094@2|Bacteria,2G77D@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
WH1_k127_2306262_0	1128421.JAGA01000002_gene693	5.027e-82	280.0	COG0566@1|root,COG0566@2|Bacteria,2NR96@2323|unclassified Bacteria	2|Bacteria	J	SpoU rRNA Methylase family	spoU	-	2.1.1.185,2.1.1.208	ko:K03218,ko:K03437,ko:K21514	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
WH1_k127_2322513_0	264732.Moth_1918	6.988e-228	719.0	COG1061@1|root,COG1061@2|Bacteria,1TPDM@1239|Firmicutes,24CK8@186801|Clostridia	186801|Clostridia	KL	Helicase conserved C-terminal domain	-	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
WH1_k127_2322513_1	572477.Alvin_0269	0.0003084	50.0	COG4715@1|root,COG4715@2|Bacteria,1R60K@1224|Proteobacteria,1S0TU@1236|Gammaproteobacteria,1WXSB@135613|Chromatiales	135613|Chromatiales	S	Zinc finger, swim domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
WH1_k127_2325540_1	309801.trd_0544	1.065e-52	203.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
WH1_k127_2325540_0	926569.ANT_08920	3.484e-72	255.0	COG4974@1|root,COG4974@2|Bacteria,2G6QW@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WH1_k127_2335513_0	926569.ANT_11400	5.337e-46	181.0	COG0768@1|root,COG0772@1|root,COG0768@2|Bacteria,COG0772@2|Bacteria,2G6NR@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
WH1_k127_2335513_1	479434.Sthe_1162	7.613e-32	128.0	COG0772@1|root,COG0772@2|Bacteria,2G6NR@200795|Chloroflexi,27Y4C@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell cycle protein	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
WH1_k127_2339389_1	926569.ANT_11990	6.017e-144	470.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi	200795|Chloroflexi	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
WH1_k127_2339389_0	926569.ANT_00880	1.669e-198	649.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WH1_k127_2372242_0	251229.Chro_2922	3.735e-182	577.0	28IMC@1|root,2Z8MV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_2372242_2	1089553.Tph_c15480	1.777e-06	55.0	COG1150@1|root,COG1150@2|Bacteria,1V8UM@1239|Firmicutes,24J4U@186801|Clostridia,42GMS@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_9
WH1_k127_2372242_1	2325.TKV_c20090	6.68e-80	276.0	COG3640@1|root,COG3640@2|Bacteria,1TPCY@1239|Firmicutes,247JM@186801|Clostridia,42F6P@68295|Thermoanaerobacterales	186801|Clostridia	D	CO dehydrogenase	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
WH1_k127_237289_4	1128421.JAGA01000002_gene1417	1.257e-27	115.0	COG2178@1|root,COG2178@2|Bacteria,2NR1U@2323|unclassified Bacteria	2|Bacteria	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
WH1_k127_237289_2	179408.Osc7112_5435	1.076e-28	120.0	COG0614@1|root,COG0614@2|Bacteria,1G79B@1117|Cyanobacteria	1117|Cyanobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
WH1_k127_237289_5	1379698.RBG1_1C00001G1508	3.212e-22	100.0	2E4KV@1|root,32ZFU@2|Bacteria,2NQ0D@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
WH1_k127_237289_1	926569.ANT_06220	1.964e-39	151.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WH1_k127_237289_0	1192034.CAP_8803	5.955e-68	246.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,2Z0HP@29|Myxococcales	28221|Deltaproteobacteria	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
WH1_k127_237289_3	326427.Cagg_1165	2.332e-28	116.0	COG1977@1|root,COG1977@2|Bacteria,2G9DU@200795|Chloroflexi,377DC@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM MoaD family protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
WH1_k127_2388637_0	984262.SGRA_3214	2.522e-85	308.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,4NMVU@976|Bacteroidetes	976|Bacteroidetes	KT	Histidine kinase-like ATPase domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HATPase_c_2,SpoIIE
WH1_k127_2389966_1	357808.RoseRS_1951	2.685e-17	94.0	COG0457@1|root,COG0457@2|Bacteria,2G9Z0@200795|Chloroflexi,377FD@32061|Chloroflexia	32061|Chloroflexia	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_2389966_0	1128421.JAGA01000002_gene1436	6.832e-104	347.0	COG3552@1|root,COG3552@2|Bacteria	2|Bacteria	S	VWA domain containing CoxE-like protein	MA20_34745	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
WH1_k127_2396219_0	247490.KSU1_C0907	1.166e-47	186.0	COG0644@1|root,COG0644@2|Bacteria,2J1WS@203682|Planctomycetes	203682|Planctomycetes	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_2396219_1	237368.SCABRO_02137	7.563e-36	146.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	prnA	-	1.14.19.9	ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
WH1_k127_2397453_3	867903.ThesuDRAFT_01585	1.503e-08	62.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WCNE@538999|Clostridiales incertae sedis	186801|Clostridia	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
WH1_k127_2397453_2	272557.APE_0122.1	2.412e-51	189.0	COG0537@1|root,arCOG00419@2157|Archaea,2XQK8@28889|Crenarchaeota	28889|Crenarchaeota	F	PFAM histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
WH1_k127_2397453_0	1150626.PHAMO_50018	1.209e-120	399.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2JPAE@204441|Rhodospirillales	204441|Rhodospirillales	I	Belongs to the thiolase family	phbA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WH1_k127_2397453_1	235909.GK3395	8.843e-94	314.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,1WFG8@129337|Geobacillus	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WH1_k127_2400915_1	1479235.KK366039_gene2195	5.428e-60	220.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1XHK6@135619|Oceanospirillales	135619|Oceanospirillales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
WH1_k127_2400915_0	926569.ANT_31030	1.412e-104	352.0	COG0052@1|root,COG0052@2|Bacteria,2G5J2@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
WH1_k127_2400915_2	138119.DSY2545	9.594e-29	118.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,260PI@186807|Peptococcaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
WH1_k127_2405629_0	326427.Cagg_2982	4.787e-149	482.0	COG4962@1|root,COG4962@2|Bacteria,2G7K7@200795|Chloroflexi,3759Z@32061|Chloroflexia	32061|Chloroflexia	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
WH1_k127_2405629_1	867845.KI911784_gene3077	5.41e-61	219.0	COG5522@1|root,COG5522@2|Bacteria	2|Bacteria	S	Integral membrane protein (intg_mem_TP0381)	ywaF	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
WH1_k127_2405629_2	1288298.rosmuc_03344	1.023e-08	56.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,2TQSJ@28211|Alphaproteobacteria,46PIQ@74030|Roseovarius	28211|Alphaproteobacteria	O	AIR synthase related protein, C-terminal domain	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
WH1_k127_2426696_0	1128421.JAGA01000002_gene1941	6.502e-23	111.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
WH1_k127_2436403_3	190486.XAC3028	9.25e-17	91.0	COG0642@1|root,COG0784@1|root,COG3292@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1X4Y5@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
WH1_k127_2436403_0	926569.ANT_24980	1.784e-294	930.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G5QR@200795|Chloroflexi	200795|Chloroflexi	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
WH1_k127_2436403_1	765420.OSCT_2586	1.102e-106	359.0	COG0016@1|root,COG0016@2|Bacteria,2G5T1@200795|Chloroflexi,374ZM@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
WH1_k127_2451637_1	1123503.KB908060_gene8	2.373e-05	52.0	COG2234@1|root,COG2234@2|Bacteria,1NE83@1224|Proteobacteria,2TSF8@28211|Alphaproteobacteria,2KFZK@204458|Caulobacterales	204458|Caulobacterales	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WH1_k127_2451637_0	694430.Natoc_3739	8.338e-55	202.0	COG0508@1|root,arCOG01706@2157|Archaea,2XUGY@28890|Euryarchaeota,23V33@183963|Halobacteria	183963|Halobacteria	C	COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh
WH1_k127_2463335_1	1297865.APJD01000049_gene5535	8.405e-95	321.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria,3JRPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WH1_k127_2463335_0	926569.ANT_05230	6.027e-269	841.0	COG0322@1|root,COG0322@2|Bacteria,2G651@200795|Chloroflexi	200795|Chloroflexi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
WH1_k127_2483111_0	926569.ANT_31290	5.476e-11	74.0	COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.2.1.96	ko:K01227,ko:K03642	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,NLPC_P60,Peptidase_M23,SH3_3,SLH
WH1_k127_2490952_4	670487.Ocepr_2242	1.053e-05	55.0	COG1555@1|root,COG1555@2|Bacteria,1WK8Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	DNA uptake protein and related DNA-binding	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
WH1_k127_2490952_2	869210.Marky_0228	1.269e-75	274.0	COG0457@1|root,COG3271@1|root,COG0457@2|Bacteria,COG3271@2|Bacteria,1WKXF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_2,TPR_8
WH1_k127_2490952_0	926569.ANT_02790	6.166e-150	501.0	COG0768@1|root,COG0768@2|Bacteria,2G7WI@200795|Chloroflexi	200795|Chloroflexi	M	NTF2-like N-terminal transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
WH1_k127_2490952_3	1121472.AQWN01000001_gene58	4.024e-74	276.0	COG4816@1|root,COG4816@2|Bacteria,1TPAQ@1239|Firmicutes,248W6@186801|Clostridia,261BX@186807|Peptococcaceae	186801|Clostridia	E	PFAM BMC domain	eutL	-	-	ko:K04026	-	-	-	-	ko00000	-	-	-	BMC
WH1_k127_2490952_1	926569.ANT_31220	7.036e-114	376.0	COG3437@1|root,COG3437@2|Bacteria,2G6QF@200795|Chloroflexi	200795|Chloroflexi	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
WH1_k127_2490952_5	646529.Desaci_3076	6.146e-05	55.0	COG2234@1|root,COG2234@2|Bacteria,1VBQF@1239|Firmicutes,25B63@186801|Clostridia,264IR@186807|Peptococcaceae	186801|Clostridia	S	PFAM Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WH1_k127_2502448_2	1047013.AQSP01000077_gene2273	2.335e-06	49.0	COG2181@1|root,COG2181@2|Bacteria	2|Bacteria	C	nitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLAC1
WH1_k127_2502448_0	246194.CHY_2406	1.243e-114	385.0	COG0247@1|root,COG0247@2|Bacteria,1UZQ0@1239|Firmicutes,24E5H@186801|Clostridia,42F8Q@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17
WH1_k127_2502448_1	926569.ANT_15430	5.679e-71	245.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2G7GS@200795|Chloroflexi	200795|Chloroflexi	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
WH1_k127_2503872_1	765420.OSCT_2889	4.332e-106	361.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi,376FV@32061|Chloroflexia	32061|Chloroflexia	M	Penicillin-Binding Protein C-terminus Family	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
WH1_k127_2503872_2	926569.ANT_30070	2.125e-75	261.0	COG0357@1|root,COG0357@2|Bacteria,2G6HF@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
WH1_k127_2503872_3	1121033.AUCF01000006_gene4102	8.472e-52	192.0	COG2606@1|root,COG2606@2|Bacteria,1RD82@1224|Proteobacteria,2U7H0@28211|Alphaproteobacteria,2JSQY@204441|Rhodospirillales	204441|Rhodospirillales	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
WH1_k127_2503872_4	351607.Acel_0160	5.391e-20	94.0	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
WH1_k127_2503872_0	926569.ANT_14080	2.051e-204	646.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi	200795|Chloroflexi	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WH1_k127_2509074_0	62928.azo1484	9.113e-183	586.0	COG2132@1|root,COG2374@1|root,COG2132@2|Bacteria,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,2VK7U@28216|Betaproteobacteria,2KY0R@206389|Rhodocyclales	206389|Rhodocyclales	Q	Endonuclease/Exonuclease/phosphatase family	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos
WH1_k127_2540308_0	383372.Rcas_0458	2.061e-33	142.0	COG0438@1|root,COG0438@2|Bacteria,2G7Z3@200795|Chloroflexi,376IC@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WH1_k127_2562508_0	926569.ANT_04130	6.741e-114	393.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8F9@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
WH1_k127_2562508_1	357808.RoseRS_2549	2.158e-22	100.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi,376TA@32061|Chloroflexia	32061|Chloroflexia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WH1_k127_2570319_2	1128421.JAGA01000001_gene2223	1.725e-55	194.0	COG0673@1|root,COG0673@2|Bacteria,2NQJC@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WH1_k127_2570319_0	935948.KE386494_gene333	4.211e-159	513.0	COG4952@1|root,COG4952@2|Bacteria,1UD8H@1239|Firmicutes,24HDU@186801|Clostridia,42FRC@68295|Thermoanaerobacterales	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
WH1_k127_2570319_1	357808.RoseRS_2886	6.362e-108	353.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi,376Z5@32061|Chloroflexia	32061|Chloroflexia	H	PFAM carbohydrate kinase, FGGY	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
WH1_k127_2593973_4	479434.Sthe_3218	2.973e-21	100.0	COG2197@1|root,COG2197@2|Bacteria,2G73R@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
WH1_k127_2593973_1	926550.CLDAP_00060	1.411e-75	264.0	COG0265@1|root,COG0265@2|Bacteria,2G6I9@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
WH1_k127_2593973_5	1365176.N186_01360	2.217e-09	63.0	arCOG07442@1|root,arCOG07442@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_2593973_0	926569.ANT_04320	5.553e-89	302.0	COG0491@1|root,COG0491@2|Bacteria,2G8XN@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WH1_k127_2593973_3	479434.Sthe_0458	1.159e-29	125.0	COG0328@1|root,COG0328@2|Bacteria,2GB0N@200795|Chloroflexi,27YNH@189775|Thermomicrobia	189775|Thermomicrobia	L	Reverse transcriptase-like	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
WH1_k127_2593973_2	485913.Krac_8827	2.768e-69	241.0	COG2872@1|root,COG2872@2|Bacteria,2GA6P@200795|Chloroflexi	200795|Chloroflexi	S	Threonyl alanyl tRNA synthetase SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
WH1_k127_2597055_0	357808.RoseRS_4577	1.169e-137	440.0	COG0209@1|root,COG1327@1|root,COG0209@2|Bacteria,COG1327@2|Bacteria,2GAH4@200795|Chloroflexi,37643@32061|Chloroflexia	32061|Chloroflexia	F	ATP-cone domain protein	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC
WH1_k127_2597055_2	1122194.AUHU01000002_gene2646	6.149e-67	253.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1T4K6@1236|Gammaproteobacteria,46DC0@72275|Alteromonadaceae	1236|Gammaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	ppkA	-	2.7.11.1	ko:K11912	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	FGE-sulfatase,PEGA,Pkinase
WH1_k127_2597055_1	926569.ANT_13390	7.853e-83	287.0	COG1428@1|root,COG1428@2|Bacteria,2G8PM@200795|Chloroflexi	200795|Chloroflexi	F	PFAM deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
WH1_k127_2597055_3	469371.Tbis_0073	3.628e-21	102.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4E6UD@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM 'Cold-shock' DNA-binding domain	cspA_2	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WH1_k127_26033_0	926569.ANT_06600	1.297e-134	458.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
WH1_k127_2604196_0	525904.Tter_2548	3.75e-20	93.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,HATPase_c,HisKA_3,Response_reg
WH1_k127_2614131_4	218284.CCDN010000001_gene294	6.216e-15	79.0	COG1234@1|root,COG1234@2|Bacteria,1VDRF@1239|Firmicutes	1239|Firmicutes	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
WH1_k127_2614131_0	926569.ANT_09930	1.229e-111	387.0	COG1300@1|root,COG1668@1|root,COG1300@2|Bacteria,COG1668@2|Bacteria,2G8CN@200795|Chloroflexi	200795|Chloroflexi	CP	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC2_membrane_2,SpoIIM
WH1_k127_2614131_1	926569.ANT_09920	6.515e-103	345.0	COG1131@1|root,COG1131@2|Bacteria,2G890@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH1_k127_2614131_2	926569.ANT_09910	1.079e-77	269.0	COG0682@1|root,COG0682@2|Bacteria,2G6QJ@200795|Chloroflexi	200795|Chloroflexi	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WH1_k127_2614131_3	926569.ANT_09900	2.179e-21	95.0	COG0558@1|root,COG0558@2|Bacteria,2G6ZT@200795|Chloroflexi	200795|Chloroflexi	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WH1_k127_2617122_3	111781.Lepto7376_1993	2.156e-40	155.0	2DCT2@1|root,32U08@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
WH1_k127_2617122_1	926569.ANT_10890	8.566e-78	264.0	COG2316@1|root,COG2316@2|Bacteria,2G6T2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM metal dependent phophohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
WH1_k127_2617122_2	926569.ANT_10900	2.272e-54	199.0	COG2949@1|root,COG2949@2|Bacteria,2G6VI@200795|Chloroflexi	200795|Chloroflexi	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
WH1_k127_2617122_0	926569.ANT_27410	3.249e-280	878.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WH1_k127_2660701_1	1265310.CCBD010000007_gene3204	1.697e-24	111.0	COG2114@1|root,COG2114@2|Bacteria,2IC2V@201174|Actinobacteria,237XA@1762|Mycobacteriaceae	201174|Actinobacteria	T	guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
WH1_k127_2660701_2	1499967.BAYZ01000030_gene1177	5.587e-20	98.0	COG1309@1|root,COG1309@2|Bacteria,2NQ1X@2323|unclassified Bacteria	2|Bacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
WH1_k127_2660701_0	358681.BBR47_16650	1.777e-36	147.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,26RP3@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	thlA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WH1_k127_2661318_0	383372.Rcas_0155	1.321e-60	228.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,2GABQ@200795|Chloroflexi,3751C@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF,GAF_2,HATPase_c,HisKA,PAS_4
WH1_k127_2673972_2	420324.KI912065_gene6637	5.751e-40	153.0	COG2114@1|root,COG2114@2|Bacteria,1R51D@1224|Proteobacteria,2TT6W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
WH1_k127_2673972_1	1463845.JOIG01000005_gene3363	5.213e-66	241.0	COG5438@1|root,COG5438@2|Bacteria,2GKJ4@201174|Actinobacteria	201174|Actinobacteria	S	YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
WH1_k127_2673972_0	266117.Rxyl_0655	2.085e-108	358.0	COG0428@1|root,COG0428@2|Bacteria,2HEM8@201174|Actinobacteria	201174|Actinobacteria	P	Mediates zinc uptake. May also transport other divalent cations	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
WH1_k127_2674706_3	926569.ANT_16600	1.621e-66	244.0	COG0544@1|root,COG0544@2|Bacteria,2G6GA@200795|Chloroflexi	200795|Chloroflexi	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
WH1_k127_2674706_2	926569.ANT_16610	3.175e-78	266.0	COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi	200795|Chloroflexi	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
WH1_k127_2674706_1	697282.Mettu_1373	9.238e-100	331.0	COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,1RRS1@1236|Gammaproteobacteria,1XE4Z@135618|Methylococcales	135618|Methylococcales	G	Belongs to the HAD-like hydrolase superfamily	-	-	3.1.3.41	ko:K01101	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
WH1_k127_2674706_5	1382306.JNIM01000001_gene67	4.775e-09	68.0	COG0457@1|root,COG0457@2|Bacteria	1382306.JNIM01000001_gene67|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_2674706_0	926569.ANT_16630	3.117e-136	442.0	COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
WH1_k127_2674706_4	1459636.NTE_03212	2.245e-30	126.0	COG0516@1|root,arCOG00612@2157|Archaea,41S7R@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
WH1_k127_26767_1	1048834.TC41_0613	2.871e-20	95.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli	91061|Bacilli	K	Transcriptional	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
WH1_k127_2683083_1	1382306.JNIM01000001_gene3684	4.458e-09	62.0	COG0491@1|root,COG0491@2|Bacteria,2G846@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_2683083_0	562970.Btus_0840	2.292e-156	516.0	COG0553@1|root,COG0553@2|Bacteria,1TQ5E@1239|Firmicutes,4HTRG@91061|Bacilli	91061|Bacilli	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
WH1_k127_2691449_3	1210884.HG799463_gene9600	1.607e-09	69.0	COG0477@1|root,COG2814@2|Bacteria,2IZ7K@203682|Planctomycetes	203682|Planctomycetes	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH1_k127_2691449_2	926569.ANT_23660	1.818e-63	235.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
WH1_k127_2691449_0	458817.Shal_2499	1.939e-108	376.0	2EXHW@1|root,33QU3@2|Bacteria,1NT7W@1224|Proteobacteria,1SM5Y@1236|Gammaproteobacteria,2QDB4@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_2691449_1	926560.KE387023_gene1933	7.245e-98	340.0	COG5624@1|root,COG5624@2|Bacteria,1WJK4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_2695388_2	552811.Dehly_0781	9.094e-09	61.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
WH1_k127_2695388_0	485916.Dtox_2025	1.358e-119	390.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1TRNK@1239|Firmicutes,24B7I@186801|Clostridia,2601S@186807|Peptococcaceae	186801|Clostridia	L	PFAM Transposase IS3 IS911	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
WH1_k127_2695388_1	649638.Trad_0272	4.676e-76	260.0	COG2309@1|root,COG2309@2|Bacteria,1WI5P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Leucyl aminopeptidase (Aminopeptidase T)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
WH1_k127_2698537_0	926569.ANT_12650	5.237e-183	578.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi	200795|Chloroflexi	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
WH1_k127_2708026_1	926569.ANT_24820	7.715e-38	154.0	COG2265@1|root,COG2265@2|Bacteria,2G6IV@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
WH1_k127_2708026_0	926550.CLDAP_16140	2.625e-85	294.0	COG1215@1|root,COG1215@2|Bacteria,2G6E4@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
WH1_k127_2718415_1	926569.ANT_19530	8.569e-63	232.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_44,Glyco_hydro_cc,Laminin_G_3,PA14
WH1_k127_2718415_2	383372.Rcas_2867	9.449e-48	173.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
WH1_k127_2718415_0	926569.ANT_19510	3.097e-79	284.0	COG0451@1|root,COG0451@2|Bacteria,2G74B@200795|Chloroflexi	200795|Chloroflexi	GM	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
WH1_k127_2729449_0	1382306.JNIM01000001_gene810	3.584e-200	693.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria	2|Bacteria	L	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,Helicase_C,N6_Mtase,ResIII,SNF2_N
WH1_k127_273731_1	1120999.JONM01000011_gene1670	1.391e-40	156.0	COG2453@1|root,COG2453@2|Bacteria,1QZXA@1224|Proteobacteria	1224|Proteobacteria	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
WH1_k127_273731_0	1382306.JNIM01000001_gene527	1.682e-72	257.0	COG1051@1|root,COG1051@2|Bacteria,2G6QH@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
WH1_k127_273731_2	926566.Terro_1435	8.299e-06	59.0	28K04@1|root,2Z9Q3@2|Bacteria,3Y344@57723|Acidobacteria,2JHZP@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_2745694_1	357808.RoseRS_4472	2.652e-12	73.0	COG0626@1|root,COG0626@2|Bacteria,2G684@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Cys Met metabolism	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
WH1_k127_2745694_0	765420.OSCT_1383	2.603e-56	205.0	COG2353@1|root,COG2353@2|Bacteria,2G8UF@200795|Chloroflexi,3775M@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
WH1_k127_2760895_4	926569.ANT_30440	3.306e-54	203.0	COG1466@1|root,COG1466@2|Bacteria,2G6XX@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
WH1_k127_2760895_6	373994.Riv7116_3042	6.312e-33	131.0	COG0517@1|root,COG0517@2|Bacteria,1G08K@1117|Cyanobacteria,1HJEI@1161|Nostocales	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CP12
WH1_k127_2760895_8	471852.Tcur_1297	5.686e-06	53.0	2ERD0@1|root,33IYN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_2760895_2	926550.CLDAP_25450	6.597e-97	329.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	2|Bacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WH1_k127_2760895_5	479434.Sthe_1705	9.301e-44	167.0	COG1974@1|root,COG1974@2|Bacteria,2G6NC@200795|Chloroflexi,27Y6E@189775|Thermomicrobia	189775|Thermomicrobia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
WH1_k127_2760895_1	926550.CLDAP_18550	1.533e-207	662.0	COG1001@1|root,COG1001@2|Bacteria,2G64P@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
WH1_k127_2760895_3	926569.ANT_08620	8.455e-67	236.0	COG1381@1|root,COG1381@2|Bacteria,2G6N7@200795|Chloroflexi	200795|Chloroflexi	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
WH1_k127_2760895_0	926569.ANT_08730	1.053e-216	685.0	COG0751@1|root,COG0752@1|root,COG0751@2|Bacteria,COG0752@2|Bacteria,2G7V0@200795|Chloroflexi	200795|Chloroflexi	J	Glycyl-tRNA synthetase alpha subunit	glyQS	-	6.1.1.14	ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA-synt_2e,tRNA_synt_2f
WH1_k127_2761987_0	1121468.AUBR01000036_gene1308	6.466e-53	205.0	COG2203@1|root,COG3437@1|root,COG3605@1|root,COG4936@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3605@2|Bacteria,COG4936@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,42JGC@68295|Thermoanaerobacterales	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,PocR,SBP_bac_3
WH1_k127_2761987_2	63737.Npun_F3677	1.836e-34	149.0	COG0784@1|root,COG3920@1|root,COG0784@2|Bacteria,COG3920@2|Bacteria,1GPYK@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_2,PAS,PAS_3,PAS_9,Response_reg
WH1_k127_2761987_1	1173027.Mic7113_3006	1.23e-39	152.0	COG4113@1|root,COG4113@2|Bacteria,1G6BG@1117|Cyanobacteria	1117|Cyanobacteria	S	PIN domain	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
WH1_k127_2764028_0	926569.ANT_29200	5.298e-140	460.0	COG4412@1|root,COG4412@2|Bacteria,2G622@200795|Chloroflexi	200795|Chloroflexi	S	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
WH1_k127_2804202_1	926550.CLDAP_13110	5.247e-96	321.0	COG1216@1|root,COG1216@2|Bacteria,2G66T@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH1_k127_2804202_2	765420.OSCT_2350	1.094e-70	258.0	COG1091@1|root,COG1091@2|Bacteria,2G6NS@200795|Chloroflexi,375G0@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
WH1_k127_2804202_3	926569.ANT_14090	2.624e-20	107.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,RDD,Yop-YscD_cpl
WH1_k127_2804202_4	926550.CLDAP_18810	2.32e-07	53.0	2EVE4@1|root,33NUJ@2|Bacteria,2G98A@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_2804202_0	1385935.N836_09955	4.352e-122	400.0	COG0604@1|root,COG0604@2|Bacteria,1G0N4@1117|Cyanobacteria,1H9U9@1150|Oscillatoriales	1117|Cyanobacteria	C	NADPH quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
WH1_k127_2811464_0	926569.ANT_14730	9.472e-142	459.0	COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi	200795|Chloroflexi	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WH1_k127_2811464_1	326427.Cagg_2794	1.435e-106	356.0	COG0482@1|root,COG0482@2|Bacteria,2G64I@200795|Chloroflexi,3751A@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
WH1_k127_2811464_2	926569.ANT_20480	4.691e-28	119.0	2ESS5@1|root,33KAI@2|Bacteria,2G7C4@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_2811464_4	945713.IALB_1682	9.817e-08	57.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
WH1_k127_2841512_0	926569.ANT_12080	1.299e-100	338.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,OapA,OapA_N,Peptidase_M23
WH1_k127_2856530_2	867845.KI911784_gene3533	2.636e-07	57.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	2.5.1.39,2.5.1.42,2.5.1.74	ko:K02548,ko:K03179,ko:K17105	ko00130,ko00564,ko01100,ko01110,map00130,map00564,map01100,map01110	M00116,M00117	R04520,R05000,R05615,R05617,R06858,R10757	RC00209,RC01171,RC02895,RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	Flavodoxin_2,UbiA
WH1_k127_2856530_0	861299.J421_0507	4.363e-82	286.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
WH1_k127_2856530_1	56780.SYN_00266	1.092e-57	205.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42M5U@68525|delta/epsilon subdivisions,2WJ06@28221|Deltaproteobacteria,2MQ54@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	TIGRFAM molybdenum cofactor synthesis domain	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
WH1_k127_2860451_0	926569.ANT_16910	1.045e-100	346.0	COG1508@1|root,COG1508@2|Bacteria,2G5VM@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma-54 factor, RpoN	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
WH1_k127_2885688_3	1521187.JPIM01000023_gene775	2.862e-48	183.0	COG0500@1|root,COG2226@2|Bacteria,2G6N8@200795|Chloroflexi,375GC@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WH1_k127_2885688_5	765911.Thivi_0061	3.075e-13	79.0	COG0589@1|root,COG0730@1|root,COG0589@2|Bacteria,COG0730@2|Bacteria,1NBKV@1224|Proteobacteria,1SHMY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Universal stress protein family	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE,Usp
WH1_k127_2885688_1	765420.OSCT_0652	3.446e-95	323.0	COG1283@1|root,COG1283@2|Bacteria,2GABF@200795|Chloroflexi,374Y2@32061|Chloroflexia	32061|Chloroflexia	P	Na+/Pi-cotransporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_Pi_cotrans
WH1_k127_2885688_2	926569.ANT_24870	1.767e-73	254.0	COG1418@1|root,COG1418@2|Bacteria,2G77Y@200795|Chloroflexi	200795|Chloroflexi	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
WH1_k127_2885688_6	7245.FBpp0260894	6.82e-05	47.0	2D82N@1|root,2T8G1@2759|Eukaryota,3930P@33154|Opisthokonta,3C8AX@33208|Metazoa,3DPBM@33213|Bilateria,425JT@6656|Arthropoda,3SV54@50557|Insecta,4587U@7147|Diptera,45Z7T@7214|Drosophilidae	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_2885688_4	926569.ANT_25150	8.031e-30	125.0	COG0736@1|root,COG0736@2|Bacteria,2G73N@200795|Chloroflexi	200795|Chloroflexi	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
WH1_k127_2885688_0	926569.ANT_25160	1.308e-104	349.0	COG0612@1|root,COG0612@2|Bacteria,2G68H@200795|Chloroflexi	200795|Chloroflexi	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WH1_k127_2895563_0	926550.CLDAP_10360	1.477e-95	330.0	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria,2G81B@200795|Chloroflexi	200795|Chloroflexi	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,Wzy_C
WH1_k127_2900011_2	485913.Krac_2639	1.117e-06	52.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
WH1_k127_2900011_1	485913.Krac_2638	4.642e-29	119.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
WH1_k127_2900011_0	485913.Krac_2637	1.51e-40	156.0	COG2208@1|root,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
WH1_k127_2916683_2	1521187.JPIM01000019_gene367	7.365e-08	56.0	2CVPW@1|root,32SXZ@2|Bacteria,2G7DV@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_2916683_0	926569.ANT_16350	6.448e-255	800.0	COG0449@1|root,COG0449@2|Bacteria,2G5T5@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
WH1_k127_2916683_1	525904.Tter_0401	3.909e-95	333.0	COG1625@1|root,COG1625@2|Bacteria,2NNXX@2323|unclassified Bacteria	2|Bacteria	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512,PDZ
WH1_k127_2927427_0	926569.ANT_16950	2.112e-129	425.0	COG0436@1|root,COG0436@2|Bacteria,2G60K@200795|Chloroflexi	200795|Chloroflexi	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WH1_k127_293858_0	671143.DAMO_2330	7.077e-107	353.0	COG0286@1|root,COG2944@1|root,COG0286@2|Bacteria,COG2944@2|Bacteria,2NNMG@2323|unclassified Bacteria	2|Bacteria	V	HsdM N-terminal domain	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HTH_3,HTH_31,HsdM_N,N6_Mtase
WH1_k127_293858_1	671143.DAMO_2330	2.337e-10	62.0	COG0286@1|root,COG2944@1|root,COG0286@2|Bacteria,COG2944@2|Bacteria,2NNMG@2323|unclassified Bacteria	2|Bacteria	V	HsdM N-terminal domain	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HTH_3,HTH_31,HsdM_N,N6_Mtase
WH1_k127_2941841_2	479434.Sthe_3395	1.238e-39	153.0	COG2998@1|root,COG2998@2|Bacteria,2G7MD@200795|Chloroflexi,27Z56@189775|Thermomicrobia	189775|Thermomicrobia	H	PBP superfamily domain	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
WH1_k127_2941841_3	479434.Sthe_3394	1.335e-25	111.0	COG2005@1|root,COG2005@2|Bacteria	2|Bacteria	P	Transcriptional regulator	-	-	-	ko:K02019,ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000,ko03000	3.A.1.6.2,3.A.1.6.4	-	-	HTH_1,PBP_like_2
WH1_k127_2941841_1	926569.ANT_08910	3.404e-81	287.0	COG0037@1|root,COG0037@2|Bacteria,2G6AD@200795|Chloroflexi	200795|Chloroflexi	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,Pribosyltran,TilS,TilS_C
WH1_k127_2941841_0	926569.ANT_09690	2.872e-139	447.0	COG1077@1|root,COG1077@2|Bacteria,2G62K@200795|Chloroflexi	200795|Chloroflexi	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
WH1_k127_2963507_1	926569.ANT_27910	1.525e-85	292.0	COG1079@1|root,COG1079@2|Bacteria,2G6BT@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WH1_k127_2963507_0	926569.ANT_27900	1.466e-127	423.0	COG4603@1|root,COG4603@2|Bacteria,2G6MU@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WH1_k127_2963507_2	29073.XP_008702318.1	0.0009645	43.0	KOG1859@1|root,KOG1259@2759|Eukaryota,38VEQ@33154|Opisthokonta,3BG3G@33208|Metazoa,3CW3X@33213|Bilateria,48A8J@7711|Chordata,495NR@7742|Vertebrata,3J4M5@40674|Mammalia,3EGQR@33554|Carnivora	33208|Metazoa	TZ	Nischarin	NISCH	GO:0003008,GO:0003013,GO:0003674,GO:0005102,GO:0005178,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006810,GO:0006996,GO:0007010,GO:0007154,GO:0007165,GO:0007264,GO:0007265,GO:0008015,GO:0008150,GO:0008152,GO:0008217,GO:0009987,GO:0010646,GO:0012505,GO:0015844,GO:0015850,GO:0015874,GO:0016020,GO:0016043,GO:0016601,GO:0019318,GO:0023051,GO:0023052,GO:0030029,GO:0030036,GO:0030334,GO:0030336,GO:0031410,GO:0031982,GO:0032228,GO:0032501,GO:0032879,GO:0032940,GO:0035556,GO:0040012,GO:0040013,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046903,GO:0048243,GO:0048519,GO:0048523,GO:0050432,GO:0050789,GO:0050794,GO:0050804,GO:0050839,GO:0050896,GO:0051179,GO:0051234,GO:0051270,GO:0051271,GO:0051716,GO:0051937,GO:0055037,GO:0065007,GO:0065008,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097708,GO:0099177,GO:2000145,GO:2000146	-	-	-	-	-	-	-	-	-	-	LRR_4,LRR_8,PX
WH1_k127_2970724_2	926569.ANT_14370	9.375e-64	225.0	COG3872@1|root,COG3872@2|Bacteria,2G5XQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1385)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF1385
WH1_k127_2970724_0	926569.ANT_00060	5.844e-79	286.0	COG2202@1|root,COG2203@1|root,COG3437@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,2G7KX@200795|Chloroflexi	2|Bacteria	T	HD domain	rsbP	-	3.1.3.3	ko:K02660,ko:K07315,ko:K07814,ko:K17763	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko01000,ko02022,ko02035,ko02044,ko03021	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HD,HD_5,HWE_HK,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,STAS,SpoIIE
WH1_k127_2970724_3	1408254.T458_07095	1.777e-08	68.0	COG0537@1|root,COG0537@2|Bacteria,1V9QX@1239|Firmicutes,4HJD9@91061|Bacilli,26Y6U@186822|Paenibacillaceae	91061|Bacilli	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
WH1_k127_2970724_1	926569.ANT_07880	4.332e-68	241.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
WH1_k127_2977534_2	357808.RoseRS_0193	0.0008115	50.0	COG1418@1|root,COG1418@2|Bacteria,2G7CI@200795|Chloroflexi,375YJ@32061|Chloroflexia	32061|Chloroflexia	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_2977534_0	926569.ANT_00670	1.96e-51	195.0	COG1994@1|root,COG1994@2|Bacteria,2G6VM@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
WH1_k127_2977534_1	479434.Sthe_0412	8.727e-23	99.0	COG4481@1|root,COG4481@2|Bacteria,2G9W8@200795|Chloroflexi,27YMV@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
WH1_k127_2977938_2	926569.ANT_00050	4.35e-184	585.0	COG1249@1|root,COG1249@2|Bacteria,2G5MR@200795|Chloroflexi	200795|Chloroflexi	C	Pyridine nucleotide-disulphide oxidoreductase dimerisation region	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
WH1_k127_2977938_3	326427.Cagg_2097	6.779e-129	425.0	COG0508@1|root,COG0508@2|Bacteria,2G5TB@200795|Chloroflexi,3759C@32061|Chloroflexia	32061|Chloroflexia	C	catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WH1_k127_2977938_0	926550.CLDAP_35340	2.212e-309	968.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2G5JU@200795|Chloroflexi	2|Bacteria	C	PFAM Transketolase central region	pdhB	-	1.2.4.4,2.2.1.1	ko:K00615,ko:K11381	ko00030,ko00280,ko00640,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00280,map00640,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00036,M00165,M00167	R01067,R01641,R01830,R06590,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00032,RC00226,RC00571,RC00627,RC01560,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
WH1_k127_2977938_4	1499967.BAYZ01000141_gene6156	1.867e-37	148.0	COG4634@1|root,COG4634@2|Bacteria,2NRUB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
WH1_k127_2977938_5	1499967.BAYZ01000141_gene6155	2.688e-31	125.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
WH1_k127_2977938_1	926550.CLDAP_03390	7.43e-240	757.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,2G5X6@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
WH1_k127_2986853_0	926550.CLDAP_12670	4.109e-73	263.0	COG3307@1|root,COG3307@2|Bacteria,2G6B1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WH1_k127_2986853_1	926550.CLDAP_17520	4.965e-07	54.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WH1_k127_2992875_1	1120999.JONM01000021_gene113	5.155e-43	166.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2VJ4R@28216|Betaproteobacteria,2KPGG@206351|Neisseriales	28216|Betaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	atzB	-	3.5.4.32	ko:K18456	-	-	-	-	ko00000,ko01000	-	-	-	Amidohydro_1
WH1_k127_2992875_0	1223523.H340_30583	1.089e-47	173.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria	201174|Actinobacteria	Q	catechol 1,2-dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
WH1_k127_3024002_0	1267533.KB906737_gene1853	3.186e-172	550.0	COG0500@1|root,COG1215@1|root,COG1215@2|Bacteria,COG2226@2|Bacteria,3Y74D@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH1_k127_3036489_0	522306.CAP2UW1_3003	9.543e-204	643.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,2VJYR@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF5110,Glyco_hydro_31
WH1_k127_3045758_0	1340493.JNIF01000002_gene1221	7.401e-71	246.0	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
WH1_k127_3045758_1	1267535.KB906767_gene2188	5.871e-25	106.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WH1_k127_3047591_1	1036674.A28LD_0210	3.217e-06	55.0	2EKDF@1|root,33E3R@2|Bacteria,1P7IA@1224|Proteobacteria,1SVDW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3047591_0	1278073.MYSTI_03329	9.21e-64	238.0	COG0515@1|root,COG0515@2|Bacteria,1NCU2@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
WH1_k127_3049_2	926550.CLDAP_21800	1.229e-82	285.0	COG0524@1|root,COG0524@2|Bacteria,2G6QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
WH1_k127_3049_0	485913.Krac_7226	1.747e-104	350.0	COG2706@1|root,COG2706@2|Bacteria,2G8EQ@200795|Chloroflexi	200795|Chloroflexi	G	Lactonase, 7-bladed beta-propeller	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
WH1_k127_3049_1	1122132.AQYH01000006_gene3457	2.701e-97	326.0	COG0451@1|root,COG0451@2|Bacteria,1MXAX@1224|Proteobacteria,2TUHZ@28211|Alphaproteobacteria,4BCZI@82115|Rhizobiaceae	1224|Proteobacteria	M	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
WH1_k127_3049_3	1123023.JIAI01000001_gene6882	8.901e-27	111.0	COG0684@1|root,COG0684@2|Bacteria,2IJW8@201174|Actinobacteria	201174|Actinobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
WH1_k127_3052812_1	945713.IALB_1079	2.164e-144	468.0	COG1866@1|root,COG1866@2|Bacteria	2|Bacteria	H	phosphoenolpyruvate carboxykinase (ATP) activity	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
WH1_k127_3052812_0	945713.IALB_1080	2.835e-148	484.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WH1_k127_3054871_0	765420.OSCT_3202	2.584e-135	458.0	COG5617@1|root,COG5617@2|Bacteria,2GBIK@200795|Chloroflexi,3780M@32061|Chloroflexia	32061|Chloroflexia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3058762_1	1128421.JAGA01000001_gene2318	6.089e-133	427.0	COG0395@1|root,COG0395@2|Bacteria,2NPII@2323|unclassified Bacteria	2|Bacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WH1_k127_3058762_0	937777.Deipe_0040	1.386e-151	498.0	COG1501@1|root,COG1501@2|Bacteria,1WM0T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3058762_2	697281.Mahau_2035	1.166e-22	100.0	COG0796@1|root,COG0796@2|Bacteria	2|Bacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Glu_race
WH1_k127_3071763_0	383372.Rcas_4096	5.237e-110	376.0	COG0477@1|root,COG2814@2|Bacteria,2G6DM@200795|Chloroflexi,375GE@32061|Chloroflexia	32061|Chloroflexia	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH1_k127_3071763_2	1123504.JQKD01000008_gene5341	1.016e-68	243.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
WH1_k127_3071763_1	706587.Desti_2991	4.67e-86	297.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182,2.1.1.184	ko:K00561,ko:K02528	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	Methyltransf_11,RrnaAD
WH1_k127_3071763_3	222984.JNCS01000004_gene2547	4.861e-30	122.0	COG0438@1|root,arCOG01411@2157|Archaea,2XUFU@28890|Euryarchaeota,23U4A@183963|Halobacteria	183963|Halobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH1_k127_3081825_0	748247.AZKH_4186	3.816e-76	269.0	COG2199@1|root,COG3829@1|root,COG4585@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,1QWNG@1224|Proteobacteria	1224|Proteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Guanylate_cyc,HATPase_c,Response_reg
WH1_k127_3095425_1	926569.ANT_22700	5.012e-138	447.0	COG1132@1|root,COG1132@2|Bacteria,2G7KA@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WH1_k127_3095425_0	926569.ANT_22690	4.727e-233	739.0	COG1132@1|root,COG1132@2|Bacteria,2G7KM@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WH1_k127_310100_0	760568.Desku_0060	6.424e-50	184.0	COG0407@1|root,COG0407@2|Bacteria,1UYXW@1239|Firmicutes,25DH8@186801|Clostridia,264CR@186807|Peptococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	2.1.1.246	ko:K14080	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00356	R09098,R10000	RC00035,RC01144,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,URO-D
WH1_k127_310100_1	867903.ThesuDRAFT_00097	5.886e-27	117.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,3WCN0@538999|Clostridiales incertae sedis	186801|Clostridia	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
WH1_k127_3101621_3	926550.CLDAP_10900	6.885e-21	107.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,2G6ZY@200795|Chloroflexi	200795|Chloroflexi	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
WH1_k127_3101621_1	926550.CLDAP_35480	1.863e-29	134.0	COG3103@1|root,COG3693@1|root,COG3103@2|Bacteria,COG3693@2|Bacteria,COG4991@2|Bacteria,2GBGU@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_42
WH1_k127_3101621_0	926569.ANT_16050	3.905e-162	521.0	COG0541@1|root,COG0541@2|Bacteria,2G627@200795|Chloroflexi	200795|Chloroflexi	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
WH1_k127_3101621_2	926569.ANT_16040	1.006e-28	128.0	COG0228@1|root,COG0228@2|Bacteria,2G7A3@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
WH1_k127_3101621_4	632245.CLP_2533	1.567e-16	81.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,36KGX@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
WH1_k127_3113679_1	67332.FM21_36130	3.079e-19	102.0	2ES6T@1|root,33JRJ@2|Bacteria,2I9QF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3113679_0	861299.J421_0072	8.856e-58	207.0	COG0116@1|root,COG0116@2|Bacteria,1ZT80@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Putative RNA methylase family UPF0020	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	UPF0020
WH1_k127_3138177_6	1128421.JAGA01000002_gene528	3.186e-45	171.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WH1_k127_3138177_0	357808.RoseRS_2373	1.535e-140	459.0	COG1215@1|root,COG1215@2|Bacteria,2GAJA@200795|Chloroflexi,376HJ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
WH1_k127_3138177_2	1128421.JAGA01000002_gene527	1.61e-115	384.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.342	ko:K16148	ko00500,ko01100,map00500,map01100	-	R02421,R11530	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WH1_k127_3138177_4	1128421.JAGA01000002_gene526	2.823e-83	293.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WH1_k127_3138177_5	383372.Rcas_3100	2.411e-76	267.0	COG1216@1|root,COG1216@2|Bacteria,2G76E@200795|Chloroflexi,377ZP@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH1_k127_3138177_1	357808.RoseRS_2377	1.596e-133	443.0	COG2244@1|root,COG2244@2|Bacteria,2G7NK@200795|Chloroflexi,3761V@32061|Chloroflexia	32061|Chloroflexia	S	PFAM polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
WH1_k127_3138177_3	316274.Haur_3579	2.705e-88	304.0	COG3307@1|root,COG3307@2|Bacteria,2GB55@200795|Chloroflexi,377AJ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WH1_k127_3160840_2	525904.Tter_0123	1.426e-16	81.0	2DSH6@1|root,33G41@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3160840_0	926550.CLDAP_07270	2.447e-42	160.0	2DT85@1|root,33J4K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3160840_1	926550.CLDAP_07260	1.645e-33	132.0	2E3MN@1|root,32YJW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3172283_1	395493.BegalDRAFT_1833	1.478e-16	93.0	COG1572@1|root,COG1572@2|Bacteria,1N1AP@1224|Proteobacteria,1SQWS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
WH1_k127_3172283_2	1128421.JAGA01000002_gene802	6.927e-08	63.0	COG3764@1|root,COG3764@2|Bacteria	2|Bacteria	M	Sortase family	ylcC	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
WH1_k127_3172283_0	525897.Dbac_0080	7.154e-73	259.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,42QPT@68525|delta/epsilon subdivisions,2WN1M@28221|Deltaproteobacteria,2M987@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM RarD protein, DMT superfamily transporter	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
WH1_k127_3175116_0	37919.EP51_26405	4.403e-146	504.0	COG0515@1|root,COG2197@1|root,COG3903@1|root,COG0515@2|Bacteria,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FUTU@85025|Nocardiaceae	201174|Actinobacteria	K	activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,NB-ARC,Pkinase,TPR_12
WH1_k127_3178922_1	911239.CF149_16456	0.0008077	46.0	COG4454@1|root,COG4454@2|Bacteria,1RC48@1224|Proteobacteria,1T0G9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Copper-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
WH1_k127_3178922_0	479434.Sthe_1816	5.108e-134	446.0	COG2217@1|root,COG2217@2|Bacteria,2G5J7@200795|Chloroflexi,27Y1J@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WH1_k127_318733_0	926569.ANT_29710	7.699e-123	403.0	COG1840@1|root,COG1840@2|Bacteria,2G5QA@200795|Chloroflexi	200795|Chloroflexi	P	extracellular solute-binding protein, family 1	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
WH1_k127_3195725_1	357808.RoseRS_0410	9.615e-16	83.0	COG1807@1|root,COG1807@2|Bacteria,2GBKP@200795|Chloroflexi,377PV@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT
WH1_k127_3195725_0	1382356.JQMP01000003_gene1423	9.069e-49	189.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
WH1_k127_3196647_1	545243.BAEV01000010_gene1092	8.255e-05	53.0	29PH6@1|root,30AFB@2|Bacteria,1W26W@1239|Firmicutes,249DA@186801|Clostridia,36GEV@31979|Clostridiaceae	186801|Clostridia	S	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
WH1_k127_3196647_0	926569.ANT_05220	3.077e-191	614.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
WH1_k127_3201426_1	926569.ANT_00850	3.925e-60	213.0	COG1350@1|root,COG1350@2|Bacteria,2G5YY@200795|Chloroflexi	200795|Chloroflexi	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WH1_k127_3201426_0	886293.Sinac_7482	9.223e-83	279.0	COG0438@1|root,COG0438@2|Bacteria,2IY41@203682|Planctomycetes	203682|Planctomycetes	M	Gkycosyl transferase family 4 group	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_3,Glycos_transf_1
WH1_k127_3205091_0	479434.Sthe_1232	1.271e-48	188.0	COG0457@1|root,COG0457@2|Bacteria	479434.Sthe_1232|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3208781_0	479434.Sthe_0669	1.754e-213	679.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi,27XRG@189775|Thermomicrobia	189775|Thermomicrobia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WH1_k127_3212200_6	926550.CLDAP_11550	5.406e-09	57.0	COG0146@1|root,COG0146@2|Bacteria,2G644@200795|Chloroflexi	200795|Chloroflexi	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
WH1_k127_3212200_1	1033734.CAET01000065_gene2151	4.061e-47	178.0	COG0317@1|root,COG0317@2|Bacteria,1VAH0@1239|Firmicutes,4HIPC@91061|Bacilli,1ZG08@1386|Bacillus	91061|Bacilli	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
WH1_k127_3212200_5	926550.CLDAP_13520	4.552e-19	97.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WH1_k127_3212200_2	926550.CLDAP_13510	1.313e-30	124.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WH1_k127_3212200_3	1461580.CCAS010000047_gene3506	1.878e-23	107.0	COG0590@1|root,COG0590@2|Bacteria,1V5NR@1239|Firmicutes,4HH7Q@91061|Bacilli,1ZGB6@1386|Bacillus	91061|Bacilli	FJ	MafB19-like deaminase	-	-	-	-	-	-	-	-	-	-	-	-	MafB19-deam,dCMP_cyt_deam_1
WH1_k127_3212200_0	926569.ANT_10590	6.376e-55	196.0	COG1051@1|root,COG1051@2|Bacteria,2G7HA@200795|Chloroflexi	200795|Chloroflexi	F	PFAM NUDIX hydrolase	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
WH1_k127_3212200_4	1121479.AUBS01000001_gene3188	9.202e-20	97.0	2CA4Z@1|root,32W4Q@2|Bacteria,1N3RF@1224|Proteobacteria,2UDC8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3212200_7	768706.Desor_2402	5.359e-08	57.0	COG0526@1|root,COG4232@1|root,COG0526@2|Bacteria,COG4232@2|Bacteria,1V9UQ@1239|Firmicutes,24DK4@186801|Clostridia,262P8@186807|Peptococcaceae	186801|Clostridia	CO	cytochrome c biogenesis protein, transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD,Thioredoxin
WH1_k127_3215521_6	1121335.Clst_1093	2.08e-17	89.0	COG0762@1|root,COG0762@2|Bacteria,1VN1M@1239|Firmicutes,24X1E@186801|Clostridia	186801|Clostridia	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
WH1_k127_3215521_4	479434.Sthe_2550	4.163e-23	103.0	COG0762@1|root,COG0762@2|Bacteria,2G9JK@200795|Chloroflexi,27ZAJ@189775|Thermomicrobia	189775|Thermomicrobia	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3215521_9	66869.JNXG01000004_gene2738	1.377e-08	61.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,419TD@629295|Streptomyces griseus group	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH1_k127_3215521_3	1128421.JAGA01000002_gene949	6.507e-31	126.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	mltA	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
WH1_k127_3215521_8	1245471.PCA10_49040	3.866e-14	79.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,1SDHP@1236|Gammaproteobacteria,1YGXI@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	yjbJ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	CsbD
WH1_k127_3215521_7	1122947.FR7_0229	9.3e-16	84.0	COG3237@1|root,COG3237@2|Bacteria,1VFTC@1239|Firmicutes,4H8NW@909932|Negativicutes	1239|Firmicutes	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
WH1_k127_3215521_0	926550.CLDAP_21020	5.406e-72	252.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH1_k127_3215521_1	926550.CLDAP_21010	1.085e-65	244.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G6ZM@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
WH1_k127_3215521_2	525904.Tter_0583	5.554e-35	147.0	2AZDP@1|root,31RMA@2|Bacteria,2NRKB@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
WH1_k127_3215521_5	926569.ANT_22500	3.79e-21	96.0	COG1550@1|root,COG1550@2|Bacteria,2G765@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
WH1_k127_3215521_10	1242864.D187_006908	0.0004583	52.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
WH1_k127_3228868_1	525909.Afer_1639	1.483e-34	139.0	COG3340@1|root,COG3340@2|Bacteria,2HH0B@201174|Actinobacteria,4CP0Q@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
WH1_k127_3228868_0	1173022.Cri9333_0546	2.151e-92	319.0	COG3385@1|root,COG3385@2|Bacteria,1G27F@1117|Cyanobacteria,1HA3W@1150|Oscillatoriales	1117|Cyanobacteria	L	SPTR Transposase IS4 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WH1_k127_3235984_2	1502852.FG94_03454	3.327e-18	90.0	2CMMQ@1|root,32SF4@2|Bacteria,1N5EJ@1224|Proteobacteria,2VVB7@28216|Betaproteobacteria,477T8@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3235984_0	987059.RBXJA2T_15743	6.216e-151	481.0	COG0583@1|root,COG0583@2|Bacteria,1R4QT@1224|Proteobacteria,2VI4T@28216|Betaproteobacteria,1KJM1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K21645	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
WH1_k127_3235984_1	864051.BurJ1DRAFT_0867	8.567e-21	94.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2VHFS@28216|Betaproteobacteria,1KJ3F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	ET	Extracellular solute-binding protein family 3	gltI	-	-	ko:K10001	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	SBP_bac_3
WH1_k127_3241503_1	485913.Krac_2132	7.733e-38	147.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	abmE	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
WH1_k127_3241503_0	485913.Krac_2131	2.886e-133	434.0	COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH1_k127_3254952_1	357808.RoseRS_3898	1.618e-54	201.0	COG0673@1|root,COG0673@2|Bacteria,2G7R0@200795|Chloroflexi,377Y3@32061|Chloroflexia	32061|Chloroflexia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WH1_k127_3254952_0	1499967.BAYZ01000057_gene4680	1.311e-89	312.0	COG1070@1|root,COG1070@2|Bacteria	2|Bacteria	G	xylulokinase activity	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
WH1_k127_3261232_0	653733.Selin_0567	1.056e-70	258.0	COG0348@1|root,COG1622@1|root,COG0348@2|Bacteria,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	vnfA	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,Fer4_5,Sigma54_activat,cNMP_binding
WH1_k127_3261232_1	589924.Ferp_0127	0.0002429	45.0	COG1622@1|root,arCOG01236@2157|Archaea	2157|Archaea	C	Heme copper-type cytochrome quinol oxidases, subunit 2	soxA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.10.3.12,1.7.2.1,1.7.99.1,1.9.3.1	ko:K02275,ko:K02826,ko:K15864	ko00190,ko00910,ko01100,ko01120,map00190,map00910,map01100,map01120	M00155,M00416,M00529	R00081,R00143,R00783,R00785,R09492	RC00016,RC00086,RC00819,RC02797	ko00000,ko00001,ko00002,ko01000	3.D.4.1,3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cupredoxin_1,Cytochrom_D1,TAT_signal
WH1_k127_3302174_0	1300345.LF41_2251	6.205e-101	350.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RMP0@1236|Gammaproteobacteria,1X4KU@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WH1_k127_3302174_3	1254432.SCE1572_14980	4.967e-42	173.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,43506@68525|delta/epsilon subdivisions,2WZB1@28221|Deltaproteobacteria,2Z1R5@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WH1_k127_3302174_1	477974.Daud_0297	2.092e-61	225.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,260S2@186807|Peptococcaceae	186801|Clostridia	GK	pfam rok	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
WH1_k127_3302174_2	485916.Dtox_2074	2.768e-44	170.0	COG3580@1|root,COG3580@2|Bacteria,1TR03@1239|Firmicutes,24987@186801|Clostridia,26153@186807|Peptococcaceae	186801|Clostridia	I	PFAM CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2229
WH1_k127_3305095_0	1268237.G114_15806	9.166e-09	67.0	COG5617@1|root,COG5617@2|Bacteria,1RJY5@1224|Proteobacteria,1SE0V@1236|Gammaproteobacteria,1Y5JR@135624|Aeromonadales	135624|Aeromonadales	S	6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PTPS_related
WH1_k127_3308166_0	926569.ANT_18400	4.225e-22	109.0	COG1287@1|root,COG1287@2|Bacteria,2G785@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3348911_1	554065.XP_005847319.1	6.703e-16	86.0	KOG3762@1|root,KOG3762@2759|Eukaryota,37WK7@33090|Viridiplantae,34IB3@3041|Chlorophyta	3041|Chlorophyta	S	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1_like
WH1_k127_3348911_0	525904.Tter_1978	1.244e-33	134.0	COG1402@1|root,COG1402@2|Bacteria,2NRPM@2323|unclassified Bacteria	2|Bacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
WH1_k127_3348959_1	1077972.ARGLB_064_00320	1.843e-90	309.0	COG3591@1|root,COG3591@2|Bacteria,2I3KX@201174|Actinobacteria	201174|Actinobacteria	E	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
WH1_k127_3348959_0	383372.Rcas_0349	9.63e-133	428.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi,374UF@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
WH1_k127_3354226_0	1120973.AQXL01000117_gene375	7.475e-123	409.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,4HAY2@91061|Bacilli	91061|Bacilli	C	Fe-S oxidoreductases	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
WH1_k127_3354226_1	1521187.JPIM01000029_gene1550	2.508e-122	397.0	COG0113@1|root,COG0113@2|Bacteria,2G5QT@200795|Chloroflexi,3756C@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the ALAD family	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
WH1_k127_336417_0	1340493.JNIF01000003_gene3616	8.549e-106	366.0	COG0457@1|root,COG0457@2|Bacteria	1340493.JNIF01000003_gene3616|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_336417_3	985665.HPL003_03425	5.504e-06	54.0	COG3866@1|root,COG4677@1|root,COG3866@2|Bacteria,COG4677@2|Bacteria,1UYI6@1239|Firmicutes,4HHAB@91061|Bacilli,2773C@186822|Paenibacillaceae	91061|Bacilli	G	Pectinesterase	pel3	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Pectinesterase
WH1_k127_336417_1	143224.JQMD01000002_gene1596	7.296e-17	86.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,1HZA1@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
WH1_k127_3378740_0	926569.ANT_16770	1.235e-89	304.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WH1_k127_3378740_1	309801.trd_0650	2.731e-75	257.0	COG0342@1|root,COG0342@2|Bacteria,2G5K5@200795|Chloroflexi,27XK4@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
WH1_k127_3404796_1	357808.RoseRS_1575	5.94e-108	357.0	COG1640@1|root,COG1640@2|Bacteria,2G668@200795|Chloroflexi,376Q1@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase, family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
WH1_k127_3404796_0	1128421.JAGA01000003_gene2724	1.064e-130	429.0	COG0448@1|root,COG0448@2|Bacteria,2NPBS@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
WH1_k127_3405372_1	1128421.JAGA01000002_gene1035	1.834e-111	374.0	COG0303@1|root,COG0303@2|Bacteria,2NP4N@2323|unclassified Bacteria	2|Bacteria	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
WH1_k127_3405372_0	525904.Tter_0998	1.765e-226	722.0	COG0317@1|root,COG0317@2|Bacteria,2NNM0@2323|unclassified Bacteria	2|Bacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	iSFV_1184.SFV_2673	ACT_4,HD_4,RelA_SpoT,TGS
WH1_k127_340568_0	1242864.D187_005571	1.282e-133	443.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
WH1_k127_340568_1	1192034.CAP_8417	2.359e-56	201.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria	1224|Proteobacteria	I	Alpha beta hydrolase	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
WH1_k127_340568_2	1192034.CAP_8417	4.082e-24	104.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria	1224|Proteobacteria	I	Alpha beta hydrolase	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
WH1_k127_3416608_1	926569.ANT_28290	7.4e-137	456.0	COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,2G7T5@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
WH1_k127_3416608_0	926550.CLDAP_24610	4.262e-150	489.0	COG0343@1|root,COG0343@2|Bacteria,2G5RE@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
WH1_k127_3416608_3	7245.FBpp0260894	6.935e-05	45.0	2D82N@1|root,2T8G1@2759|Eukaryota,3930P@33154|Opisthokonta,3C8AX@33208|Metazoa,3DPBM@33213|Bilateria,425JT@6656|Arthropoda,3SV54@50557|Insecta,4587U@7147|Diptera,45Z7T@7214|Drosophilidae	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3416608_2	1167006.UWK_00832	1.36e-17	84.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WPKC@28221|Deltaproteobacteria,2MJE6@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
WH1_k127_3417720_0	926550.CLDAP_35910	5.5e-84	288.0	COG2521@1|root,COG2521@2|Bacteria,2G7RX@200795|Chloroflexi	200795|Chloroflexi	S	Methyltransferase domain	-	-	-	ko:K06983	-	-	-	-	ko00000	-	-	-	Methyltransf_11
WH1_k127_3420547_3	357808.RoseRS_1768	1.464e-51	183.0	COG0554@1|root,COG0554@2|Bacteria,2G5TV@200795|Chloroflexi,3751K@32061|Chloroflexia	32061|Chloroflexia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
WH1_k127_3420547_0	926569.ANT_27600	1.902e-122	406.0	COG0578@1|root,COG0578@2|Bacteria,2G63S@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
WH1_k127_3420547_4	926569.ANT_27590	2.109e-51	192.0	COG0479@1|root,COG0479@2|Bacteria,2G659@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
WH1_k127_3420547_5	273075.Ta1003	2.571e-12	73.0	COG2009@1|root,arCOG02244@2157|Archaea	2157|Archaea	C	COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit	sdhC	-	-	ko:K00241,ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
WH1_k127_3420547_2	42256.RradSPS_1185	4.833e-64	224.0	COG0693@1|root,COG0693@2|Bacteria,2GMMW@201174|Actinobacteria	201174|Actinobacteria	V	Intracellular protease	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
WH1_k127_3420547_1	1380390.JIAT01000010_gene4304	2.139e-107	367.0	COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4CPDV@84995|Rubrobacteria	84995|Rubrobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
WH1_k127_3428626_1	357808.RoseRS_1119	2.436e-72	260.0	COG0793@1|root,COG0793@2|Bacteria,2GAAX@200795|Chloroflexi,374TM@32061|Chloroflexia	32061|Chloroflexia	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_S41,Tricorn_C1
WH1_k127_3428626_0	926569.ANT_07850	1.649e-108	356.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WH1_k127_3428626_2	479434.Sthe_1955	1.347e-30	126.0	COG3191@1|root,COG3191@2|Bacteria,2G83F@200795|Chloroflexi,27YT6@189775|Thermomicrobia	189775|Thermomicrobia	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
WH1_k127_3431479_0	1297742.A176_01806	2.417e-25	119.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3431479_1	1121904.ARBP01000022_gene3520	3.213e-15	87.0	COG1621@1|root,COG1621@2|Bacteria,4PNCP@976|Bacteroidetes	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_343214_0	926569.ANT_16410	1.158e-88	309.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G901@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
WH1_k127_343214_2	926569.ANT_16420	2.538e-22	104.0	COG1430@1|root,COG1430@2|Bacteria	2|Bacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
WH1_k127_343214_1	926569.ANT_16430	1.089e-44	167.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_16430|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3438585_0	926550.CLDAP_33690	3.484e-67	247.0	COG3307@1|root,COG3307@2|Bacteria,2G6TE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WH1_k127_3460951_0	1249627.D779_3597	3.115e-05	55.0	COG0417@1|root,COG0417@2|Bacteria	2|Bacteria	L	DNA replication proofreading	polB	-	2.7.7.7	ko:K02336,ko:K06877,ko:K07501	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol_B,DNA_pol_B_exo1,DNA_pol_B_exo2,RNase_H_2
WH1_k127_3462310_0	937777.Deipe_0063	5.676e-76	266.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
WH1_k127_3465200_0	240292.Ava_2771	2.445e-36	152.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HKT0@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
WH1_k127_3465200_1	580332.Slit_0623	2.862e-14	85.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2VJV5@28216|Betaproteobacteria,44VNA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	histidine kinase dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_3,PAS_9,Response_reg
WH1_k127_3475632_0	926560.KE387023_gene3595	1.848e-138	479.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12
WH1_k127_3475632_1	326427.Cagg_1166	6.167e-107	349.0	COG2414@1|root,COG2414@2|Bacteria,2G5XP@200795|Chloroflexi,376PZ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WH1_k127_3478764_2	1117108.PAALTS15_28541	1.197e-22	102.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HJYK@91061|Bacilli,26TVZ@186822|Paenibacillaceae	91061|Bacilli	Q	O-methyltransferase	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25,Ubie_methyltran
WH1_k127_3478764_0	644966.Tmar_1561	0.0	1039.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3WCCN@538999|Clostridiales incertae sedis	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WH1_k127_3478764_1	1122939.ATUD01000002_gene1465	3.759e-51	196.0	COG0644@1|root,COG0644@2|Bacteria,2HQ8K@201174|Actinobacteria,4CRS9@84995|Rubrobacteria	84995|Rubrobacteria	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3483089_2	357808.RoseRS_2858	4.761e-58	210.0	COG3375@1|root,COG3375@2|Bacteria,2G8MH@200795|Chloroflexi,37765@32061|Chloroflexia	32061|Chloroflexia	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3483089_3	326427.Cagg_0827	2.6e-54	198.0	COG0279@1|root,COG0279@2|Bacteria,2G6QD@200795|Chloroflexi,3773E@32061|Chloroflexia	32061|Chloroflexia	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
WH1_k127_3483089_0	945713.IALB_2901	5.486e-131	429.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	menC	GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C,MR_MLE_C,MR_MLE_N
WH1_k127_3483089_1	357808.RoseRS_2891	5.588e-82	276.0	COG1486@1|root,COG1486@2|Bacteria,2G5M6@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
WH1_k127_3497628_1	398767.Glov_0388	4.603e-38	155.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
WH1_k127_3497628_2	1322246.BN4_12682	6.31e-19	97.0	COG0500@1|root,COG2226@2|Bacteria,1QXUA@1224|Proteobacteria,42QNQ@68525|delta/epsilon subdivisions,2WMN4@28221|Deltaproteobacteria,2MDRV@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
WH1_k127_3497628_0	926569.ANT_25410	7.654e-269	837.0	COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
WH1_k127_3498788_2	1449044.JMLE01000002_gene4297	1.453e-15	82.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria,1W9JV@1268|Micrococcaceae	201174|Actinobacteria	G	pyruvate phosphate dikinase, PEP	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
WH1_k127_3498788_1	926550.CLDAP_26340	7.37e-19	100.0	COG1572@1|root,COG3292@1|root,COG1572@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Beta_helix,CARDB,Cleaved_Adhesin,DUF4465,Glyco_tran_WbsX,fn3
WH1_k127_3498788_0	649638.Trad_0671	2.095e-21	94.0	COG0609@1|root,COG0609@2|Bacteria,1WIRB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	fecD	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
WH1_k127_3501508_0	926569.ANT_02040	1.013e-240	754.0	COG1012@1|root,COG1012@2|Bacteria,2G61H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
WH1_k127_3506244_0	756272.Plabr_4000	2.041e-08	57.0	2ADBE@1|root,3130V@2|Bacteria,2IZYT@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_351590_0	926569.ANT_31760	5.071e-82	278.0	COG1428@1|root,COG1428@2|Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
WH1_k127_3556364_1	880073.Calab_0920	5.123e-62	232.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	-	-	-	-	-	-	-	-	-	SSF
WH1_k127_3556364_0	160799.PBOR_30720	8.332e-81	276.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HF4F@91061|Bacilli,26VTM@186822|Paenibacillaceae	91061|Bacilli	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
WH1_k127_356252_0	926569.ANT_21660	3.467e-13	74.0	COG4974@1|root,COG4974@2|Bacteria,2G6CI@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WH1_k127_3567581_0	555088.DealDRAFT_1874	1.085e-99	340.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,42KC5@68298|Syntrophomonadaceae	186801|Clostridia	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
WH1_k127_3567581_2	926569.ANT_04330	1.889e-51	192.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WH1_k127_3567581_3	644966.Tmar_1104	6.64e-22	101.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
WH1_k127_3567581_1	383372.Rcas_3322	5.162e-66	233.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,375K6@32061|Chloroflexia	32061|Chloroflexia	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
WH1_k127_3567581_4	1157637.KB892135_gene3384	1.288e-05	48.0	COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter	iolTC	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
WH1_k127_3567742_1	1160137.KB907307_gene3883	1.963e-05	47.0	COG1376@1|root,COG1376@2|Bacteria,2GJBA@201174|Actinobacteria,4FVQS@85025|Nocardiaceae	201174|Actinobacteria	S	L,D-transpeptidase catalytic domain	lppS	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016787,GO:0017171,GO:0019538,GO:0030203,GO:0030312,GO:0042546,GO:0043170,GO:0044085,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0140096,GO:1901135,GO:1901564	-	-	-	-	-	-	-	-	-	-	YkuD
WH1_k127_3567742_0	530564.Psta_1177	2.127e-73	257.0	COG2040@1|root,COG2040@2|Bacteria,2J3GR@203682|Planctomycetes	203682|Planctomycetes	H	Homocysteine S-methyltransferase	-	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
WH1_k127_3568787_0	926569.ANT_09210	2.446e-205	664.0	COG0745@1|root,COG2114@1|root,COG5000@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP,dCache_1,dCache_3
WH1_k127_3573939_0	1121396.KB893068_gene1412	1.048e-53	203.0	COG0535@1|root,COG0535@2|Bacteria,1MYFX@1224|Proteobacteria,42SB0@68525|delta/epsilon subdivisions,2WPF4@28221|Deltaproteobacteria,2MMXH@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
WH1_k127_3573939_3	335543.Sfum_3987	2.284e-06	57.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
WH1_k127_3573939_1	1265505.ATUG01000001_gene4122	5.138e-21	101.0	2AGE3@1|root,316JX@2|Bacteria,1NHX8@1224|Proteobacteria,42X67@68525|delta/epsilon subdivisions,2WT7A@28221|Deltaproteobacteria,2MM7G@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
WH1_k127_3573939_2	1121396.KB893068_gene1412	5.19e-15	84.0	COG0535@1|root,COG0535@2|Bacteria,1MYFX@1224|Proteobacteria,42SB0@68525|delta/epsilon subdivisions,2WPF4@28221|Deltaproteobacteria,2MMXH@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
WH1_k127_3579492_2	926550.CLDAP_37580	2.758e-118	391.0	COG0001@1|root,COG0001@2|Bacteria,2G7SS@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WH1_k127_3579492_6	395961.Cyan7425_4822	2.566e-29	130.0	COG1562@1|root,COG1562@2|Bacteria,1G0U6@1117|Cyanobacteria,3KFRW@43988|Cyanothece	1117|Cyanobacteria	I	PFAM Squalene phytoene synthase	-	-	2.5.1.21	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R00702,R02872,R06223	RC00362,RC00796,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	SQS_PSY
WH1_k127_3579492_5	1382356.JQMP01000004_gene517	9.811e-54	204.0	COG2234@1|root,COG2234@2|Bacteria,2G8I9@200795|Chloroflexi,27Z9R@189775|Thermomicrobia	189775|Thermomicrobia	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WH1_k127_3579492_0	592015.HMPREF1705_01067	9.527e-186	600.0	COG2414@1|root,COG2414@2|Bacteria	2|Bacteria	C	aldehyde ferredoxin oxidoreductase activity	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WH1_k127_3579492_3	926569.ANT_11190	2.308e-100	330.0	COG0717@1|root,COG0717@2|Bacteria,2G7HJ@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
WH1_k127_3579492_4	926569.ANT_13710	4.91e-80	277.0	COG0179@1|root,COG0179@2|Bacteria,2G6H8@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
WH1_k127_3579492_1	886293.Sinac_3058	6.763e-141	468.0	COG1249@1|root,COG1249@2|Bacteria,2IY39@203682|Planctomycetes	203682|Planctomycetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	sthA	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
WH1_k127_3579492_7	207559.Dde_0429	4.199e-08	57.0	COG0500@1|root,COG1216@1|root,COG4627@1|root,COG1216@2|Bacteria,COG2226@2|Bacteria,COG4627@2|Bacteria,1N73D@1224|Proteobacteria,42XDU@68525|delta/epsilon subdivisions,2WRMM@28221|Deltaproteobacteria,2MD77@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WH1_k127_3610888_0	340.xcc-b100_1196	7.517e-41	157.0	COG0454@1|root,COG0454@2|Bacteria,1RIFC@1224|Proteobacteria,1S6DF@1236|Gammaproteobacteria,1X6KK@135614|Xanthomonadales	135614|Xanthomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
WH1_k127_3610888_1	204669.Acid345_3980	9.389e-26	110.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_8
WH1_k127_3624780_3	926569.ANT_25840	7.215e-65	229.0	COG0484@1|root,COG0484@2|Bacteria,2G61V@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock protein DnaJ domain protein	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
WH1_k127_3624780_4	1541065.JRFE01000006_gene4631	6.769e-18	85.0	COG0484@1|root,COG0484@2|Bacteria,1FZXU@1117|Cyanobacteria,3VIBF@52604|Pleurocapsales	1117|Cyanobacteria	O	DnaJ-class molecular chaperone with C-terminal Zn finger domain	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
WH1_k127_3624780_1	926569.ANT_27990	1.842e-101	351.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria	926569.ANT_27990|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3624780_0	926569.ANT_28000	9.091e-187	603.0	COG2203@1|root,COG2204@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria,2GBJN@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,Response_reg
WH1_k127_3624780_2	926550.CLDAP_29080	1.151e-71	251.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
WH1_k127_3627177_0	926569.ANT_30210	3.76e-21	96.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	salK	-	2.7.13.3	ko:K07680,ko:K07778,ko:K11617,ko:K14988	ko02020,ko02024,map02020,map02024	M00476,M00479,M00481,M00522,M00754	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
WH1_k127_3628266_1	300852.55772835	2.813e-81	282.0	COG0479@1|root,COG0479@2|Bacteria,1WIEW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
WH1_k127_3628266_0	309801.trd_0331	6.413e-241	760.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,27XUB@189775|Thermomicrobia	189775|Thermomicrobia	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
WH1_k127_3628266_2	926569.ANT_22160	9.9e-18	85.0	COG2142@1|root,COG2142@2|Bacteria,2G7EN@200795|Chloroflexi	200795|Chloroflexi	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
WH1_k127_3633354_1	926569.ANT_04640	9e-51	184.0	COG2852@1|root,COG2852@2|Bacteria,2G78G@200795|Chloroflexi	200795|Chloroflexi	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3633354_0	1304874.JAFY01000007_gene2147	1.058e-189	606.0	COG0031@1|root,COG0031@2|Bacteria,3T9XD@508458|Synergistetes	508458|Synergistetes	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	PALP
WH1_k127_3633354_2	215803.DB30_8110	4.895e-30	132.0	COG0673@1|root,COG0673@2|Bacteria,1N0VK@1224|Proteobacteria,43C12@68525|delta/epsilon subdivisions,2WXMX@28221|Deltaproteobacteria,2Z37R@29|Myxococcales	28221|Deltaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WH1_k127_3633354_3	370438.PTH_1019	1.123e-05	50.0	COG2362@1|root,COG2362@2|Bacteria,1TSUZ@1239|Firmicutes,24CY1@186801|Clostridia,26655@186807|Peptococcaceae	186801|Clostridia	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
WH1_k127_3634391_0	926569.ANT_11350	1.924e-93	309.0	COG1690@1|root,COG1690@2|Bacteria,2G5NT@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
WH1_k127_3634391_1	886293.Sinac_5188	2.108e-29	125.0	COG0388@1|root,COG0388@2|Bacteria,2J21T@203682|Planctomycetes	203682|Planctomycetes	S	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
WH1_k127_3637346_0	926569.ANT_03860	4.599e-202	641.0	COG0621@1|root,COG0621@2|Bacteria,2G5ZJ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
WH1_k127_3637346_1	646529.Desaci_3227	1.257e-14	84.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,24M2Q@186801|Clostridia,261QR@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
WH1_k127_3649928_1	323098.Nwi_0773	3.326e-62	224.0	COG2010@1|root,COG2010@2|Bacteria,1MYNE@1224|Proteobacteria,2V9Z1@28211|Alphaproteobacteria,3K5DU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
WH1_k127_3649928_0	671143.DAMO_0778	1.395e-151	480.0	COG5013@1|root,COG5013@2|Bacteria	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	narG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00370,ko:K17050	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685	Molybdopterin,Molydop_binding,Nitr_red_alph_N
WH1_k127_3661249_0	485913.Krac_12092	1.727e-253	789.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WH1_k127_3663242_2	1120966.AUBU01000017_gene703	0.0003133	43.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KU8@768503|Cytophagia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
WH1_k127_3663242_0	926569.ANT_09770	1.991e-199	633.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WH1_k127_3663242_1	926569.ANT_09760	5.797e-82	282.0	COG0772@1|root,COG0772@2|Bacteria,2G6GW@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
WH1_k127_3678441_0	1244869.H261_12211	2.182e-176	559.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,2JP9C@204441|Rhodospirillales	204441|Rhodospirillales	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	-	-	-	-	-	-	-	-	-	-	ArgK,B12-binding,MM_CoA_mutase
WH1_k127_3690287_2	1449080.JQMV01000003_gene322	0.00038	51.0	COG2244@1|root,COG2244@2|Bacteria,1WIZQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_C
WH1_k127_3690287_1	324602.Caur_1371	5.448e-07	62.0	2AQIF@1|root,31FR6@2|Bacteria,2GB3Q@200795|Chloroflexi,377V2@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3690287_0	926569.ANT_30200	1.113e-96	331.0	COG2197@1|root,COG3055@1|root,COG2197@2|Bacteria,COG3055@2|Bacteria,2G6NU@200795|Chloroflexi	200795|Chloroflexi	KT	Kelch repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Kelch_1,Kelch_4
WH1_k127_3705426_0	383372.Rcas_3701	2.931e-68	247.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GAAG@200795|Chloroflexi,374S4@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
WH1_k127_3705833_1	926569.ANT_00900	7.697e-59	209.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi	200795|Chloroflexi	L	PFAM AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
WH1_k127_3705833_0	324602.Caur_2175	4.729e-98	336.0	2BEFV@1|root,32CHX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3708744_3	926550.CLDAP_23690	0.0001546	46.0	COG1765@1|root,COG1765@2|Bacteria,2G6Y1@200795|Chloroflexi	200795|Chloroflexi	O	PFAM OsmC family protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
WH1_k127_3708744_2	1552123.EP57_08345	9.541e-15	80.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,4HKJV@91061|Bacilli,26N3P@186820|Listeriaceae	91061|Bacilli	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
WH1_k127_3708744_0	316274.Haur_0038	5.2e-143	461.0	COG1013@1|root,COG1013@2|Bacteria,2G679@200795|Chloroflexi,374ZH@32061|Chloroflexia	32061|Chloroflexia	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
WH1_k127_3708744_1	504728.K649_05290	2.394e-104	344.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1WIAF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COGs COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase alpha subunit	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
WH1_k127_3722959_3	926569.ANT_18650	4.643e-47	174.0	COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WH1_k127_3722959_2	926569.ANT_18660	2.007e-73	254.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
WH1_k127_3722959_1	926569.ANT_18670	1.892e-103	364.0	COG3225@1|root,COG3225@2|Bacteria	2|Bacteria	-	-	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
WH1_k127_3722959_6	1117379.BABA_21266	0.0006055	49.0	2BT98@1|root,32NEM@2|Bacteria,1U25D@1239|Firmicutes,4INJ8@91061|Bacilli,1ZNJT@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
WH1_k127_3722959_0	926569.ANT_18690	3.336e-166	534.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WH1_k127_3722959_4	926560.KE387027_gene896	1.419e-10	72.0	COG4758@1|root,COG4758@2|Bacteria,1WKNW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
WH1_k127_3722959_5	710421.Mycch_3687	1.104e-06	50.0	COG1053@1|root,COG1053@2|Bacteria,2GIXG@201174|Actinobacteria,233J3@1762|Mycobacteriaceae	201174|Actinobacteria	C	Succinate dehydrogenase fumarate reductase flavoprotein subunit	-	-	1.3.99.4	ko:K05898	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R09884	RC00991	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
WH1_k127_3724415_0	926569.ANT_31100	1.971e-87	305.0	COG0747@1|root,COG0747@2|Bacteria,2G7MC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WH1_k127_3724415_1	1128421.JAGA01000002_gene272	3.829e-33	135.0	COG0340@1|root,COG0340@2|Bacteria,2NPG2@2323|unclassified Bacteria	2|Bacteria	H	biotin acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
WH1_k127_3733961_2	926550.CLDAP_11930	8.067e-09	68.0	COG2132@1|root,COG5617@1|root,COG2132@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3,PTPS_related
WH1_k127_3733961_0	926569.ANT_20570	1.519e-136	444.0	COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi	200795|Chloroflexi	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
WH1_k127_3733961_1	926550.CLDAP_18010	9.363e-19	87.0	COG0045@1|root,COG0045@2|Bacteria,2G68A@200795|Chloroflexi	200795|Chloroflexi	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
WH1_k127_3738410_2	1121335.Clst_0501	1.222e-13	72.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WGEA@541000|Ruminococcaceae	186801|Clostridia	C	glutamate synthase	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
WH1_k127_3738410_0	383372.Rcas_4032	4.04e-61	223.0	COG0492@1|root,COG0492@2|Bacteria,2GANS@200795|Chloroflexi,37736@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
WH1_k127_3738410_3	1340493.JNIF01000003_gene1690	5.491e-05	54.0	2DMGW@1|root,32REM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-B_box
WH1_k127_3739404_0	383372.Rcas_2745	3.909e-62	226.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2G8PX@200795|Chloroflexi,376RK@32061|Chloroflexia	32061|Chloroflexia	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_2
WH1_k127_3750922_2	926569.ANT_31060	3.455e-37	148.0	COG1011@1|root,COG1011@2|Bacteria,2G787@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
WH1_k127_3750922_1	1304865.JAGF01000001_gene3051	1.208e-54	206.0	COG0454@1|root,COG0456@2|Bacteria,2I0BQ@201174|Actinobacteria,4F17M@85016|Cellulomonadaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WH1_k127_3750922_3	99598.Cal7507_0942	5.493e-37	153.0	COG1670@1|root,COG1670@2|Bacteria,1GK85@1117|Cyanobacteria,1HTG0@1161|Nostocales	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WH1_k127_3750922_4	1294265.JCM21738_3766	2.67e-31	133.0	COG1670@1|root,COG1670@2|Bacteria,1V3Q8@1239|Firmicutes,4HH72@91061|Bacilli,1ZQWD@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WH1_k127_3750922_0	204669.Acid345_4165	7.989e-113	373.0	COG0460@1|root,COG0460@2|Bacteria,3Y2VY@57723|Acidobacteria,2JHYQ@204432|Acidobacteriia	2|Bacteria	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
WH1_k127_3750922_5	324602.Caur_1656	1.872e-06	49.0	COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi,375HF@32061|Chloroflexia	32061|Chloroflexia	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
WH1_k127_3753674_0	63737.Npun_R1294	1.295e-118	405.0	COG0236@1|root,COG1028@1|root,COG3321@1|root,COG4221@1|root,COG0236@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,1G1IB@1117|Cyanobacteria,1HJKD@1161|Nostocales	1117|Cyanobacteria	IQ	TIGRFAM Polyketide-type polyunsaturated fatty acid synthase, PfaA	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
WH1_k127_3753674_1	211165.AJLN01000037_gene2022	2.962e-106	360.0	COG0236@1|root,COG3321@1|root,COG4221@1|root,COG0236@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,1G1IB@1117|Cyanobacteria,1JKE5@1189|Stigonemataceae	1117|Cyanobacteria	IQ	Polyketide synthase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
WH1_k127_3815369_0	926550.CLDAP_21850	2.703e-30	132.0	COG1651@1|root,COG1651@2|Bacteria,2G8TG@200795|Chloroflexi	200795|Chloroflexi	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
WH1_k127_3815369_1	1051632.TPY_1590	1.998e-09	67.0	COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,2489D@186801|Clostridia,3WCT6@538999|Clostridiales incertae sedis	186801|Clostridia	C	Alanine dehydrogenase/PNT, N-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
WH1_k127_3816232_2	410359.Pcal_1384	1.816e-05	55.0	COG1145@1|root,arCOG02187@2157|Archaea	2157|Archaea	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
WH1_k127_3816232_0	357808.RoseRS_2505	6.76e-68	235.0	COG4636@1|root,COG4636@2|Bacteria,2G90F@200795|Chloroflexi,377N7@32061|Chloroflexia	32061|Chloroflexia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
WH1_k127_3816232_1	1123252.ATZF01000001_gene1449	3.117e-57	203.0	COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,1UWW7@1239|Firmicutes,4INA2@91061|Bacilli,27CJS@186824|Thermoactinomycetaceae	91061|Bacilli	Q	Polyketide synthase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KR,Ketoacyl-synt_C,PS-DH,ketoacyl-synt
WH1_k127_3820067_2	926569.ANT_29670	9.142e-57	200.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WH1_k127_3820067_0	926569.ANT_29680	1.474e-230	729.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WH1_k127_3820067_3	1121123.AUAO01000001_gene1562	3.22e-30	131.0	2D8TI@1|root,32TRX@2|Bacteria,1N5N2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3820067_1	357808.RoseRS_0796	4.074e-69	237.0	COG3458@1|root,COG3458@2|Bacteria,2G5R9@200795|Chloroflexi,376UE@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM Acetyl xylan esterase	-	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
WH1_k127_382899_0	1128421.JAGA01000003_gene3642	2.729e-89	303.0	COG0294@1|root,COG0294@2|Bacteria,2NNN7@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
WH1_k127_382899_1	479434.Sthe_1922	1.235e-10	63.0	COG0801@1|root,COG0801@2|Bacteria,2G6YT@200795|Chloroflexi,27YCY@189775|Thermomicrobia	189775|Thermomicrobia	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
WH1_k127_3829693_4	1035308.AQYY01000001_gene1406	7.462e-13	70.0	COG0524@1|root,COG0524@2|Bacteria,1UW7Z@1239|Firmicutes,25MKR@186801|Clostridia,2660K@186807|Peptococcaceae	186801|Clostridia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
WH1_k127_3829693_1	926569.ANT_19370	2.114e-80	282.0	COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi	200795|Chloroflexi	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
WH1_k127_3829693_3	35754.JNYJ01000017_gene6263	7.478e-15	80.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4D9TH@85008|Micromonosporales	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
WH1_k127_3829693_0	926569.ANT_24710	1.003e-99	334.0	COG2041@1|root,COG2041@2|Bacteria,2G6ES@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
WH1_k127_3829693_2	926569.ANT_00640	9.119e-21	92.0	COG0503@1|root,COG0503@2|Bacteria,2G8J8@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
WH1_k127_3837729_4	926569.ANT_05360	3.548e-39	152.0	COG1243@1|root,COG1243@2|Bacteria,2G5ZZ@200795|Chloroflexi	200795|Chloroflexi	BK	Radical_SAM C-terminal domain	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
WH1_k127_3837729_6	395961.Cyan7425_3371	7.041e-16	80.0	2E4DR@1|root,32Z92@2|Bacteria,1G9TM@1117|Cyanobacteria,3KJ2M@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3837729_5	1173026.Glo7428_2619	3.328e-29	118.0	2E46S@1|root,32Z2Q@2|Bacteria,1G7MJ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3837729_1	1117647.M5M_07610	1.969e-107	361.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,1RQT8@1236|Gammaproteobacteria,1J6J9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Microcin C7 resistance	ldcA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009050,GO:0009056,GO:0009254,GO:0009987,GO:0016787,GO:0019538,GO:0030203,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	iAPECO1_1312.APECO1_304,iECABU_c1320.ECABU_c14580,iECED1_1282.ECED1_1334,iECOK1_1307.ECOK1_1338,iECS88_1305.ECS88_1255,iLF82_1304.LF82_1171,iNRG857_1313.NRG857_06085,iSFV_1184.SFV_1201,iSFxv_1172.SFxv_1357,iS_1188.S1271,iUMN146_1321.UM146_11125,iUTI89_1310.UTI89_C1378,ic_1306.c1641	Peptidase_S66
WH1_k127_3837729_2	309801.trd_1860	9.609e-103	341.0	COG1173@1|root,COG1173@2|Bacteria,2G6HB@200795|Chloroflexi,27XKI@189775|Thermomicrobia	189775|Thermomicrobia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
WH1_k127_3837729_0	1382356.JQMP01000004_gene623	9.849e-121	399.0	COG0601@1|root,COG0601@2|Bacteria,2G7SK@200795|Chloroflexi,27XXY@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WH1_k127_3837729_3	1382356.JQMP01000004_gene624	3.262e-101	348.0	COG0747@1|root,COG0747@2|Bacteria,2G860@200795|Chloroflexi,27XM9@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WH1_k127_3856646_0	383372.Rcas_2749	7.298e-34	145.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3864098_0	926569.ANT_08350	4.922e-51	191.0	COG0243@1|root,COG1034@1|root,COG0243@2|Bacteria,COG1034@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WH1_k127_3864098_1	926569.ANT_08360	1.744e-26	115.0	COG1005@1|root,COG1005@2|Bacteria,2G62Y@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
WH1_k127_3948691_0	926569.ANT_14300	2.91e-86	290.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH1_k127_3948691_1	1089548.KI783301_gene2272	1.697e-30	130.0	COG1814@1|root,COG1814@2|Bacteria,1V011@1239|Firmicutes,4HWJY@91061|Bacilli	91061|Bacilli	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
WH1_k127_3948691_2	639282.DEFDS_1260	4.474e-18	85.0	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	fdhA	-	1.17.1.10,1.17.1.11,1.17.1.9	ko:K00123,ko:K05299,ko:K22341	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WH1_k127_3949809_2	330214.NIDE3489	3.88e-99	338.0	COG4243@1|root,COG4243@2|Bacteria	2|Bacteria	S	quinone binding	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	-
WH1_k127_3949809_3	383372.Rcas_0816	2.473e-27	114.0	COG1917@1|root,COG1917@2|Bacteria,2G7C7@200795|Chloroflexi,377HW@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_3949809_0	370438.PTH_2455	7.269e-139	451.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,261M6@186807|Peptococcaceae	186801|Clostridia	S	PFAM Fic DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
WH1_k127_3949809_1	926569.ANT_14860	2.429e-114	375.0	COG1167@1|root,COG1167@2|Bacteria,2G61E@200795|Chloroflexi	200795|Chloroflexi	EK	PFAM Aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
WH1_k127_3952567_0	439235.Dalk_3399	1.095e-70	257.0	COG0715@1|root,COG0715@2|Bacteria,1QVUU@1224|Proteobacteria,43CS5@68525|delta/epsilon subdivisions,2X5E2@28221|Deltaproteobacteria,2MQ33@213118|Desulfobacterales	28221|Deltaproteobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
WH1_k127_3952567_1	1000565.METUNv1_01055	3.222e-16	86.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,2VS1F@28216|Betaproteobacteria,2KZRB@206389|Rhodocyclales	206389|Rhodocyclales	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH1_k127_3957136_1	443143.GM18_1345	1.472e-78	271.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,43SF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
WH1_k127_3957136_0	357808.RoseRS_2549	9.066e-127	415.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi,376TA@32061|Chloroflexia	32061|Chloroflexia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WH1_k127_3979810_0	204669.Acid345_3113	1.981e-125	409.0	COG0665@1|root,COG0665@2|Bacteria,3Y8UA@57723|Acidobacteria	57723|Acidobacteria	E	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO
WH1_k127_3992152_3	697284.ERIC2_c10030	2.612e-46	171.0	COG1250@1|root,COG1250@2|Bacteria,1TSZI@1239|Firmicutes,4HBK3@91061|Bacilli,26UKH@186822|Paenibacillaceae	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WH1_k127_3992152_0	1122221.JHVI01000007_gene2245	8.717e-85	287.0	COG0739@1|root,COG0739@2|Bacteria,1WM9M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WH1_k127_3992152_2	1122221.JHVI01000007_gene2245	3.487e-51	202.0	COG0739@1|root,COG0739@2|Bacteria,1WM9M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WH1_k127_3992152_4	926550.CLDAP_10230	3.091e-39	158.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	ratA	-	3.5.1.104	ko:K21449,ko:K22278	-	-	-	-	ko00000,ko01000,ko02000	1.B.40.2	-	-	LysM,PG_binding_1,PG_binding_4,YkuD
WH1_k127_3992152_1	926554.KI912664_gene1585	2.946e-64	228.0	COG0183@1|root,COG0183@2|Bacteria,1WIPU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WH1_k127_399535_0	926550.CLDAP_31360	8.137e-89	308.0	2DZNW@1|root,32VEY@2|Bacteria,2G8XI@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_399535_1	309801.trd_1592	2.955e-32	132.0	COG1216@1|root,COG1216@2|Bacteria,2G8DR@200795|Chloroflexi,27XHV@189775|Thermomicrobia	189775|Thermomicrobia	S	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
WH1_k127_4005372_2	883.DvMF_2767	7.866e-15	78.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,2M9KC@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	hemD	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
WH1_k127_4005372_0	338963.Pcar_3063	5.355e-85	291.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria,43T66@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
WH1_k127_4005372_1	644966.Tmar_1263	6.529e-84	291.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WDC1@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
WH1_k127_4036553_3	383372.Rcas_2042	2.63e-88	300.0	COG3284@1|root,COG3284@2|Bacteria,2GA8J@200795|Chloroflexi,375R4@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
WH1_k127_4036553_2	1521187.JPIM01000055_gene3652	5.871e-106	350.0	COG0580@1|root,COG0580@2|Bacteria,2G813@200795|Chloroflexi,376PT@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
WH1_k127_4036553_0	383372.Rcas_2044	1.676e-177	560.0	COG2376@1|root,COG2376@2|Bacteria,2G80E@200795|Chloroflexi,376JR@32061|Chloroflexia	32061|Chloroflexia	G	TIGRFAM dihydroxyacetone kinase, DhaK subunit	-	-	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
WH1_k127_4036553_4	383372.Rcas_2045	1.085e-77	266.0	COG1461@1|root,COG1461@2|Bacteria,2G8FK@200795|Chloroflexi,377ZB@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM dihydroxyacetone kinase, L subunit	-	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
WH1_k127_4036553_1	357808.RoseRS_1768	5.04e-165	522.0	COG0554@1|root,COG0554@2|Bacteria,2G5TV@200795|Chloroflexi,3751K@32061|Chloroflexia	32061|Chloroflexia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
WH1_k127_4040567_1	880072.Desac_1035	2.068e-105	348.0	COG0067@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0070@2|Bacteria,1NZ4D@1224|Proteobacteria,43B3T@68525|delta/epsilon subdivisions,2X6HR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	GXGXG motif	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6,GXGXG
WH1_k127_4040567_0	926569.ANT_08730	7.044e-140	458.0	COG0751@1|root,COG0752@1|root,COG0751@2|Bacteria,COG0752@2|Bacteria,2G7V0@200795|Chloroflexi	200795|Chloroflexi	J	Glycyl-tRNA synthetase alpha subunit	glyQS	-	6.1.1.14	ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA-synt_2e,tRNA_synt_2f
WH1_k127_4070963_0	926550.CLDAP_40550	2.2e-96	337.0	COG0652@1|root,COG0652@2|Bacteria,2G8IA@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase,Thioredoxin_4
WH1_k127_4070963_1	1321778.HMPREF1982_02132	2.118e-09	61.0	2AFI1@1|root,315IM@2|Bacteria,1UUJJ@1239|Firmicutes,256YF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4072122_0	1038860.AXAP01000027_gene1889	0.0	1190.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JSZE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
WH1_k127_4072122_1	1382356.JQMP01000003_gene1475	4.789e-83	278.0	COG1878@1|root,COG1878@2|Bacteria,2GBDZ@200795|Chloroflexi,27Z1S@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
WH1_k127_4075761_0	383372.Rcas_0864	1.029e-61	230.0	COG0318@1|root,COG0318@2|Bacteria,2GBKJ@200795|Chloroflexi,3781K@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4081226_1	926569.ANT_26470	5.726e-84	288.0	COG2848@1|root,COG2848@2|Bacteria,2G6HQ@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterised ACR (DUF711)	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
WH1_k127_4081226_0	518766.Rmar_1548	1.349e-189	625.0	COG1086@1|root,COG1086@2|Bacteria	2|Bacteria	GM	Polysaccharide biosynthesis protein	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Bac_transf,CoA_binding_3,Glycos_transf_4,HTH_45,LicD
WH1_k127_4088053_0	926550.CLDAP_06400	0.0	1256.0	COG3383@1|root,COG3383@2|Bacteria,2GBH3@200795|Chloroflexi	200795|Chloroflexi	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WH1_k127_4114312_2	479434.Sthe_0669	1.41e-92	308.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi,27XRG@189775|Thermomicrobia	189775|Thermomicrobia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WH1_k127_4114312_1	292564.Cyagr_2551	2.129e-107	353.0	COG0730@1|root,COG0730@2|Bacteria,1G5ZV@1117|Cyanobacteria,22TPE@167375|Cyanobium	1117|Cyanobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WH1_k127_4114312_0	926569.ANT_21050	7.013e-116	381.0	COG0402@1|root,COG1437@1|root,COG0402@2|Bacteria,COG1437@2|Bacteria,2G6DG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,CYTH
WH1_k127_4127134_1	485913.Krac_2174	1.416e-19	91.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
WH1_k127_4127134_0	926569.ANT_07850	8.44e-68	240.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WH1_k127_4161246_0	572547.Amico_0354	8.036e-66	244.0	COG0697@1|root,COG0697@2|Bacteria,3TB45@508458|Synergistetes	508458|Synergistetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WH1_k127_4162336_0	926569.ANT_13340	1.173e-109	376.0	COG1472@1|root,COG1472@2|Bacteria,2G7PD@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
WH1_k127_4168530_1	926569.ANT_01910	7.952e-88	294.0	COG0082@1|root,COG0082@2|Bacteria,2G645@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
WH1_k127_4168530_0	926569.ANT_01920	9.229e-164	533.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2G5K8@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
WH1_k127_4168530_2	926569.ANT_29460	1.739e-57	208.0	COG0757@1|root,COG0757@2|Bacteria,2G70K@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
WH1_k127_4168530_3	926550.CLDAP_15410	2.667e-41	153.0	COG2025@1|root,COG2025@2|Bacteria,2G6PP@200795|Chloroflexi	200795|Chloroflexi	C	electron transfer flavoprotein, alpha subunit	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
WH1_k127_4171333_0	926569.ANT_09490	7.867e-07	57.0	COG3296@1|root,COG3296@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
WH1_k127_4173377_1	926569.ANT_29550	3.117e-51	196.0	COG0631@1|root,COG0631@2|Bacteria,2G6R4@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
WH1_k127_4173377_0	1382306.JNIM01000001_gene2376	1.71e-162	524.0	COG0146@1|root,COG0146@2|Bacteria,2G644@200795|Chloroflexi	200795|Chloroflexi	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
WH1_k127_4188470_0	604354.TSIB_1211	5.735e-40	162.0	arCOG09492@1|root,arCOG09492@2157|Archaea,2Y3AH@28890|Euryarchaeota,244X9@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4193584_1	321327.CYA_0685	9.238e-57	210.0	COG0834@1|root,COG0834@2|Bacteria,1GJVF@1117|Cyanobacteria,1H1U5@1129|Synechococcus	1117|Cyanobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
WH1_k127_4193584_0	1183438.GKIL_0689	2.436e-84	291.0	COG0206@1|root,COG0206@2|Bacteria,1G0AN@1117|Cyanobacteria	1117|Cyanobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000910,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0032153,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
WH1_k127_4197263_0	479434.Sthe_3242	1.641e-29	131.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
WH1_k127_4197833_1	765420.OSCT_1373	9.017e-46	177.0	COG2931@1|root,COG2931@2|Bacteria,2GBI9@200795|Chloroflexi,377IY@32061|Chloroflexia	32061|Chloroflexia	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
WH1_k127_4197833_0	1242864.D187_006755	2.327e-145	485.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,42NCK@68525|delta/epsilon subdivisions,2WMCF@28221|Deltaproteobacteria,2YTU4@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
WH1_k127_4197833_2	243231.GSU0137	1.317e-08	64.0	COG2199@1|root,COG3706@2|Bacteria,1NFQH@1224|Proteobacteria,42S2B@68525|delta/epsilon subdivisions,2WX0B@28221|Deltaproteobacteria,43VG9@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM type IV pilus assembly PilZ	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
WH1_k127_4215270_0	926550.CLDAP_18940	4.374e-59	214.0	COG0472@1|root,COG0472@2|Bacteria,2G6H5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
WH1_k127_4215270_1	1128421.JAGA01000002_gene405	8.227e-07	55.0	2EV3Q@1|root,33NIR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4235070_3	639283.Snov_1730	9.788e-40	148.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2TRNJ@28211|Alphaproteobacteria,3F100@335928|Xanthobacteraceae	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WH1_k127_4235070_1	296591.Bpro_0731	5.634e-123	397.0	COG0684@1|root,COG0684@2|Bacteria,1MUWV@1224|Proteobacteria,2VIJI@28216|Betaproteobacteria,4ACBZ@80864|Comamonadaceae	28216|Betaproteobacteria	H	Pfam:Methyltransf_6	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
WH1_k127_4235070_0	762376.AXYL_02027	6.889e-136	437.0	COG0451@1|root,COG0451@2|Bacteria,1MWVE@1224|Proteobacteria,2VZBS@28216|Betaproteobacteria,3T8SH@506|Alcaligenaceae	28216|Betaproteobacteria	M	NAD(P)H-binding	-	-	1.1.1.203	ko:K18981	ko00053,map00053	-	R10841	RC00066	ko00000,ko00001,ko01000	-	-	-	Epimerase
WH1_k127_4235070_2	639283.Snov_1909	4.461e-96	325.0	COG3386@1|root,COG3386@2|Bacteria,1MXVD@1224|Proteobacteria,2TVCW@28211|Alphaproteobacteria,3F0T7@335928|Xanthobacteraceae	28211|Alphaproteobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053,ko:K02352	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
WH1_k127_4237123_0	1121405.dsmv_3084	2.971e-78	274.0	COG0477@1|root,COG2814@2|Bacteria,1R842@1224|Proteobacteria,42QBY@68525|delta/epsilon subdivisions,2WKB6@28221|Deltaproteobacteria,2MHNH@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH1_k127_4243281_1	316274.Haur_0045	1.4e-22	115.0	COG1572@1|root,COG1572@2|Bacteria,2GAID@200795|Chloroflexi,376C4@32061|Chloroflexia	32061|Chloroflexia	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4243281_0	1379698.RBG1_1C00001G1428	1.218e-29	139.0	COG2911@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NS5I@2323|unclassified Bacteria	2|Bacteria	U	FlgD Ig-like domain	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Cytochrome_C554,DUF11,FlgD_ig,PKD,SLH
WH1_k127_4243281_2	324602.Caur_3820	0.0004185	47.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
WH1_k127_4243544_1	357808.RoseRS_3479	7.484e-56	204.0	COG2353@1|root,COG2353@2|Bacteria,2G8UF@200795|Chloroflexi,3775M@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
WH1_k127_4243544_0	1120953.AUBH01000004_gene3096	1.837e-67	245.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,1RRQE@1236|Gammaproteobacteria,466I8@72275|Alteromonadaceae	1236|Gammaproteobacteria	EH	COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases	ghrA	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C
WH1_k127_4247291_2	383372.Rcas_2308	2.838e-39	149.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2G69H@200795|Chloroflexi,37507@32061|Chloroflexia	32061|Chloroflexia	C	pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
WH1_k127_4247291_0	316274.Haur_0680	1.152e-63	228.0	COG0697@1|root,COG0697@2|Bacteria,2G8KQ@200795|Chloroflexi,377W3@32061|Chloroflexia	32061|Chloroflexia	EG	EamA-like transporter family	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
WH1_k127_4247291_1	926569.ANT_18510	1.898e-49	181.0	COG2986@1|root,COG2986@2|Bacteria,2G66R@200795|Chloroflexi	200795|Chloroflexi	E	PFAM phenylalanine histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
WH1_k127_4249332_0	1476583.DEIPH_ctg103orf0062	2.88e-33	140.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
WH1_k127_4267001_0	926550.CLDAP_20090	2.144e-129	424.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_3585	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_B
WH1_k127_4267001_2	926550.CLDAP_20100	1.224e-32	135.0	COG0723@1|root,COG0723@2|Bacteria,2G7BG@200795|Chloroflexi	200795|Chloroflexi	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
WH1_k127_4267001_1	926569.ANT_02860	2.147e-54	198.0	COG0349@1|root,COG0349@2|Bacteria,2G74K@200795|Chloroflexi	200795|Chloroflexi	L	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
WH1_k127_4268469_2	264732.Moth_2011	3.337e-40	153.0	COG5573@1|root,COG5573@2|Bacteria,1V7GS@1239|Firmicutes	1239|Firmicutes	S	PFAM PilT protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WH1_k127_4268469_3	324602.Caur_1907	0.0008285	47.0	2BQFZ@1|root,32JBD@2|Bacteria,2G9Y6@200795|Chloroflexi,377WA@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4268469_1	1382306.JNIM01000001_gene1216	3.121e-42	158.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Ribonuc_L-PSP
WH1_k127_4268469_0	926550.CLDAP_27570	8.073e-150	482.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH1_k127_4270283_0	926569.ANT_31720	4.568e-311	959.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
WH1_k127_4270283_1	926569.ANT_31220	1.304e-66	239.0	COG3437@1|root,COG3437@2|Bacteria,2G6QF@200795|Chloroflexi	200795|Chloroflexi	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
WH1_k127_4314857_2	1210884.HG799466_gene12816	1.653e-38	166.0	COG2203@1|root,COG3852@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WH1_k127_4314857_1	926569.ANT_11630	5.599e-118	387.0	COG0407@1|root,COG0407@2|Bacteria,2G6BE@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
WH1_k127_4314857_0	1304874.JAFY01000002_gene661	6.154e-156	501.0	COG0477@1|root,COG2814@2|Bacteria,3TACG@508458|Synergistetes	508458|Synergistetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH1_k127_4322682_2	765420.OSCT_3068	1.391e-57	211.0	COG2339@1|root,COG2339@2|Bacteria,2G946@200795|Chloroflexi,375Y0@32061|Chloroflexia	32061|Chloroflexia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
WH1_k127_4322682_3	1009370.ALO_05268	1.803e-32	144.0	COG0613@1|root,COG0613@2|Bacteria,1VCKE@1239|Firmicutes,4H57V@909932|Negativicutes	909932|Negativicutes	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
WH1_k127_4322682_1	926569.ANT_22570	1.48e-93	319.0	COG0392@1|root,COG0392@2|Bacteria,2G6EN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
WH1_k127_4322682_0	309801.trd_0440	1.901e-110	390.0	COG2006@1|root,COG2006@2|Bacteria,2GA2Y@200795|Chloroflexi,27YWH@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
WH1_k127_4322682_4	926550.CLDAP_06980	0.0002003	45.0	COG0406@1|root,COG0406@2|Bacteria,2G731@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
WH1_k127_4326798_0	888727.HMPREF9092_0137	2.336e-12	79.0	COG3210@1|root,COG3210@2|Bacteria,1VP3A@1239|Firmicutes,24UCN@186801|Clostridia,3WDPR@538999|Clostridiales incertae sedis	186801|Clostridia	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4326798_1	382464.ABSI01000010_gene3728	5.473e-08	53.0	COG4799@1|root,COG4799@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	pccB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0031974,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0070013,GO:0071704,GO:0072329,GO:1901575	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WH1_k127_4337364_0	1108045.GORHZ_040_00160	1.281e-21	104.0	COG1309@1|root,COG1309@2|Bacteria,2IN1Z@201174|Actinobacteria,4GEX4@85026|Gordoniaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WH1_k127_4337364_1	1828.JOKB01000007_gene2607	2.414e-15	80.0	2A651@1|root,30UXH@2|Bacteria,2IERM@201174|Actinobacteria,4G38Y@85025|Nocardiaceae	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
WH1_k127_4353397_0	760568.Desku_0188	5.822e-150	492.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K16885,ko:K16886	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_4,Fer4_7,FlpD,Pyr_redox_2
WH1_k127_4370415_1	383372.Rcas_1313	4.191e-59	210.0	28JE3@1|root,2Z98B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
WH1_k127_4370415_0	1304865.JAGF01000001_gene124	1.132e-86	293.0	28I7A@1|root,2Z8A6@2|Bacteria,2IF3R@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4370672_2	1121405.dsmv_0891	2.617e-23	104.0	2E0F6@1|root,32W1G@2|Bacteria,1N6I3@1224|Proteobacteria,42V01@68525|delta/epsilon subdivisions,2WQWS@28221|Deltaproteobacteria,2MMAB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4370672_0	555779.Dthio_PD0052	5.788e-176	569.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42MF0@68525|delta/epsilon subdivisions,2WMC1@28221|Deltaproteobacteria,2MGHZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
WH1_k127_4370672_1	1121405.dsmv_0889	1.314e-102	339.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42NRE@68525|delta/epsilon subdivisions,2WM0E@28221|Deltaproteobacteria,2MJFH@213118|Desulfobacterales	28221|Deltaproteobacteria	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
WH1_k127_4376214_0	1122182.KB903825_gene750	3.367e-212	681.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8,SLH,fn3
WH1_k127_4376214_1	1232410.KI421413_gene574	2.138e-09	71.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,1MU3S@1224|Proteobacteria,42SPI@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	COG1404 Subtilisin-like serine proteases	-	-	3.4.21.111	ko:K12685,ko:K20754	-	-	-	-	ko00000,ko01000,ko01002,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	-	-	Inhibitor_I9,Peptidase_S8
WH1_k127_4378186_1	1385514.N782_17565	1.7e-06	50.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4I33T@91061|Bacilli,2YA43@289201|Pontibacillus	91061|Bacilli	EG	Multidrug transporter	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WH1_k127_4378186_0	1123320.KB889689_gene484	1.522e-26	120.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_2,Pkinase
WH1_k127_4381197_0	926569.ANT_02540	1.33e-73	260.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
WH1_k127_4401493_0	926569.ANT_08950	1.792e-44	186.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
WH1_k127_4403694_3	926569.ANT_01380	4.482e-24	101.0	COG0601@1|root,COG0601@2|Bacteria,2G68Q@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WH1_k127_4403694_2	926569.ANT_01390	1.376e-139	450.0	COG1173@1|root,COG1173@2|Bacteria,2G5PJ@200795|Chloroflexi	200795|Chloroflexi	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
WH1_k127_4403694_1	926569.ANT_01400	1.493e-154	495.0	COG0444@1|root,COG0444@2|Bacteria,2G5PT@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
WH1_k127_4403694_0	926569.ANT_01410	9.988e-159	505.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WH1_k127_4411516_1	1144343.PMI41_04074	1.386e-17	89.0	COG0524@1|root,COG0524@2|Bacteria,1MYB5@1224|Proteobacteria,2U1N7@28211|Alphaproteobacteria,43PA2@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
WH1_k127_4411516_0	1122611.KB903944_gene1223	1.706e-48	183.0	COG1486@1|root,COG1486@2|Bacteria,2GK80@201174|Actinobacteria,4EIA4@85012|Streptosporangiales	201174|Actinobacteria	G	Family 4 glycosyl hydrolase	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
WH1_k127_4441403_0	402777.KB235903_gene853	2.692e-156	503.0	COG1232@1|root,COG1232@2|Bacteria,1G05M@1117|Cyanobacteria,1H8M6@1150|Oscillatoriales	1117|Cyanobacteria	H	Protoporphyrinogen oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
WH1_k127_4441403_1	203124.Tery_4497	4.277e-23	115.0	COG3391@1|root,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria,1H803@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
WH1_k127_4446438_2	118166.JH976538_gene5065	1.381e-22	113.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9,Response_reg
WH1_k127_4446438_3	926569.ANT_28890	1.27e-05	51.0	COG0697@1|root,COG0697@2|Bacteria,2G6ZR@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WH1_k127_4446438_0	926569.ANT_25670	1.001e-97	339.0	2EDFC@1|root,3366P@2|Bacteria,2G7IW@200795|Chloroflexi	200795|Chloroflexi	S	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
WH1_k127_4446438_1	926569.ANT_25680	8.566e-62	221.0	COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi	200795|Chloroflexi	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
WH1_k127_4461734_0	1089550.ATTH01000001_gene787	5.548e-251	814.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1FIKI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Bacterial DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
WH1_k127_4470160_6	596152.DesU5LDRAFT_2913	6.944e-09	59.0	COG0500@1|root,COG2226@2|Bacteria,1RFBE@1224|Proteobacteria,42VEH@68525|delta/epsilon subdivisions,2WVST@28221|Deltaproteobacteria,2MA0A@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
WH1_k127_4470160_7	1123024.AUII01000008_gene1834	7.138e-05	47.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4DXGV@85010|Pseudonocardiales	201174|Actinobacteria	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
WH1_k127_4470160_0	1410624.JNKK01000002_gene931	1.686e-169	543.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,27IPA@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
WH1_k127_4470160_1	765420.OSCT_2914	1.55e-125	420.0	COG1233@1|root,COG3349@1|root,COG1233@2|Bacteria,COG3349@2|Bacteria	2|Bacteria	CH	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'	pds	-	1.17.8.1,1.3.3.15,1.3.3.4,1.3.5.5,1.3.5.6	ko:K00231,ko:K00514,ko:K02293,ko:K09879,ko:K21677	ko00860,ko00906,ko01100,ko01110,map00860,map00906,map01100,map01110	M00097,M00121	R03222,R04178,R04786,R04787,R04798,R04800,R07510,R07511,R07541,R07560,R07857,R07858,R09652,R09653,R09654,R09656,R09658	RC00885,RC01214,RC01901,RC01958,RC01959,RC01965,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
WH1_k127_4470160_5	1521187.JPIM01000022_gene633	6.79e-25	108.0	COG0296@1|root,COG0296@2|Bacteria,2G9SJ@200795|Chloroflexi,377QN@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase family 13 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,CBM_48
WH1_k127_4470160_4	867845.KI911784_gene3573	4.435e-31	124.0	COG1694@1|root,COG1694@2|Bacteria,2G9Y9@200795|Chloroflexi,377WH@32061|Chloroflexia	32061|Chloroflexia	F	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
WH1_k127_4470160_3	926550.CLDAP_16790	1.157e-54	205.0	COG2129@1|root,COG2129@2|Bacteria,2G8MC@200795|Chloroflexi	200795|Chloroflexi	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
WH1_k127_4470160_2	649638.Trad_1708	2.27e-74	259.0	COG1475@1|root,COG1475@2|Bacteria,1WIS1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Domain of unknown function (DUF4032)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,ParBc
WH1_k127_4477890_0	1448860.BBJO01000014_gene1409	5.244e-59	225.0	COG1501@1|root,arCOG03663@2157|Archaea,2XVVM@28890|Euryarchaeota,23UPD@183963|Halobacteria	183963|Halobacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
WH1_k127_4477890_1	1379698.RBG1_1C00001G1066	3.601e-10	61.0	COG0260@1|root,COG0260@2|Bacteria,2NNKH@2323|unclassified Bacteria	2|Bacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141	3.4.11.1,3.4.11.5	ko:K01255,ko:K01259	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00135,R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
WH1_k127_4481165_2	269799.Gmet_2618	1.102e-23	106.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42UV6@68525|delta/epsilon subdivisions,2WP1R@28221|Deltaproteobacteria,43TFM@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
WH1_k127_4481165_0	84531.JMTZ01000030_gene152	6.396e-123	400.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,1X4EG@135614|Xanthomonadales	135614|Xanthomonadales	G	6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
WH1_k127_4481165_1	326427.Cagg_3190	4.768e-47	177.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,374UD@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
WH1_k127_4486221_0	316274.Haur_4998	1.49e-75	286.0	COG3210@1|root,COG3391@1|root,COG5184@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Autotransporter,Beta_helix,CHU_C,Calx-beta,DUF4347,FG-GAP,HYR,VCBS
WH1_k127_4486221_2	663278.Ethha_0791	1.919e-08	59.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,3WGDE@541000|Ruminococcaceae	186801|Clostridia	NU	type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
WH1_k127_4486221_1	1128427.KB904821_gene3767	1.249e-14	80.0	COG0443@1|root,COG0443@2|Bacteria,1G0XC@1117|Cyanobacteria,1H8M1@1150|Oscillatoriales	1117|Cyanobacteria	O	Heat shock 70 kDa protein	dnaK1	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WH1_k127_4486657_1	926550.CLDAP_06980	3.192e-32	133.0	COG0406@1|root,COG0406@2|Bacteria,2G731@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
WH1_k127_4486657_0	765420.OSCT_0044	1.78e-126	415.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi,37723@32061|Chloroflexia	32061|Chloroflexia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WH1_k127_4486657_2	926550.CLDAP_07710	3.742e-08	61.0	COG0845@1|root,COG0845@2|Bacteria,2G93B@200795|Chloroflexi	200795|Chloroflexi	MV	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
WH1_k127_4491670_1	377629.TERTU_2831	4.862e-05	52.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,2PNV7@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	M	Peptidase family M23	nlpD	GO:0000920,GO:0001896,GO:0005575,GO:0005623,GO:0008150,GO:0008219,GO:0009279,GO:0009987,GO:0012501,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0043085,GO:0044093,GO:0044462,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071944	-	ko:K06194,ko:K12943	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
WH1_k127_4491670_0	96561.Dole_0034	9.243e-70	266.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2MHQU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
WH1_k127_4497505_0	926560.KE387023_gene2443	3.692e-181	576.0	COG3408@1|root,COG3408@2|Bacteria,1WM3Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Alkaline and neutral invertase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_100
WH1_k127_4497505_1	697281.Mahau_2034	1.599e-94	317.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,42EMP@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM ketose-bisphosphate aldolase, class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
WH1_k127_449819_1	926569.ANT_00380	3.162e-28	124.0	2ANS9@1|root,31DS7@2|Bacteria,2G7CA@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_449819_0	926569.ANT_00390	8.318e-75	265.0	COG1070@1|root,COG1070@2|Bacteria,2G6JV@200795|Chloroflexi	200795|Chloroflexi	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	MutL
WH1_k127_4509041_1	765420.OSCT_1944	2.771e-61	214.0	COG0330@1|root,COG0330@2|Bacteria,2GAMW@200795|Chloroflexi,3772P@32061|Chloroflexia	32061|Chloroflexia	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WH1_k127_4509041_0	497964.CfE428DRAFT_0142	1.665e-131	430.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WH1_k127_4509041_2	1470593.BW43_05219	1.168e-05	51.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG2303 Choline dehydrogenase and related flavoproteins	-	-	1.1.5.9	ko:K19813	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R00305	RC00066	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
WH1_k127_4521502_2	1128421.JAGA01000003_gene3738	7.237e-09	67.0	COG4745@1|root,COG4745@2|Bacteria	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WH1_k127_4521502_1	926569.ANT_28020	1.163e-26	126.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M15_4
WH1_k127_4521502_3	1036674.A28LD_0291	7.645e-09	68.0	COG2199@1|root,COG3447@1|root,COG3447@2|Bacteria,COG3706@2|Bacteria,1R7GZ@1224|Proteobacteria,1RZEZ@1236|Gammaproteobacteria,2QGNZ@267893|Idiomarinaceae	1236|Gammaproteobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,MASE1
WH1_k127_4521502_0	765420.OSCT_2604	7.172e-33	144.0	COG3437@1|root,COG3437@2|Bacteria,2GBI7@200795|Chloroflexi,376P2@32061|Chloroflexia	32061|Chloroflexia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5,PAS,PAS_9,Response_reg
WH1_k127_4524111_1	32057.KB217478_gene361	1.12e-19	89.0	COG3201@1|root,COG3201@2|Bacteria,1GAIX@1117|Cyanobacteria	1117|Cyanobacteria	H	nicotinamide mononucleotide transporter	-	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
WH1_k127_4524111_2	292459.STH235	1.875e-11	76.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia	186801|Clostridia	P	phosphate binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
WH1_k127_4524111_0	1167006.UWK_00832	1.937e-55	201.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WPKC@28221|Deltaproteobacteria,2MJE6@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
WH1_k127_4525620_0	926550.CLDAP_36400	1.282e-107	359.0	COG3250@1|root,COG3250@2|Bacteria,2G6ZW@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glyco_hydro_2_N
WH1_k127_4525620_1	1499967.BAYZ01000076_gene800	1.256e-86	302.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K02012,ko:K07114	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	1.A.13.2.2,1.A.13.2.3,3.A.1.10	-	-	SBP_bac_11,VWA,VWA_2,VWA_3
WH1_k127_4541906_0	926550.CLDAP_09690	1.906e-14	85.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
WH1_k127_4547005_1	1123288.SOV_3c02640	2.262e-08	55.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H2UN@909932|Negativicutes	909932|Negativicutes	S	ABC transporter, ATP-binding protein	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WH1_k127_4547005_0	1479237.JMLY01000001_gene898	7.068e-16	82.0	COG5450@1|root,COG5450@2|Bacteria,1N76R@1224|Proteobacteria,1SD4N@1236|Gammaproteobacteria,46CAJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
WH1_k127_4547005_3	1056820.KB900630_gene1406	0.0005913	44.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,2PP0F@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WH1_k127_4547005_2	1123242.JH636434_gene3495	0.0001577	53.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
WH1_k127_4567880_0	379066.GAU_2166	2.72e-219	694.0	COG1866@1|root,COG1866@2|Bacteria,1ZSTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
WH1_k127_4567880_1	765420.OSCT_2981	8.286e-113	372.0	COG0039@1|root,COG0039@2|Bacteria,2G61S@200795|Chloroflexi,374VR@32061|Chloroflexia	32061|Chloroflexia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
WH1_k127_4567880_2	316274.Haur_0844	3.168e-21	96.0	COG3872@1|root,COG3872@2|Bacteria,2G5XQ@200795|Chloroflexi,375GD@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
WH1_k127_4598449_2	1122217.KB899616_gene1297	5.799e-32	131.0	COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4H3ZP@909932|Negativicutes	909932|Negativicutes	S	Serine aminopeptidase, S33	est	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
WH1_k127_4598449_1	926569.ANT_16070	1.426e-97	338.0	COG0006@1|root,COG0006@2|Bacteria,2G6AH@200795|Chloroflexi	200795|Chloroflexi	E	peptidase M24	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Peptidase_M24
WH1_k127_4598449_4	926569.ANT_23670	0.0004016	49.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
WH1_k127_4598449_3	1397696.KK211189_gene2556	6.527e-12	69.0	2DR03@1|root,339MB@2|Bacteria,1VK6Y@1239|Firmicutes,4HR34@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4598449_0	1458427.BAWN01000013_gene920	4.125e-142	463.0	COG1373@1|root,COG1373@2|Bacteria,1R3UA@1224|Proteobacteria,2VQ1T@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
WH1_k127_4605636_0	479434.Sthe_0337	0.0	1203.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi,27XEH@189775|Thermomicrobia	189775|Thermomicrobia	J	Anticodon-binding domain of tRNA	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
WH1_k127_4605636_1	536227.CcarbDRAFT_4777	6.169e-37	141.0	COG2872@1|root,COG2872@2|Bacteria,1UHS6@1239|Firmicutes,24AK0@186801|Clostridia,36GRN@31979|Clostridiaceae	186801|Clostridia	S	Threonyl alanyl tRNA synthetase SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
WH1_k127_4608519_1	671143.DAMO_2739	1.239e-99	339.0	COG1203@1|root,COG1203@2|Bacteria	2|Bacteria	L	DNA/RNA hybrid annealing activity	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C
WH1_k127_4608519_0	671143.DAMO_2738	2.485e-174	570.0	28JGZ@1|root,2Z9AI@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K19136	-	-	-	-	ko00000,ko02048	-	-	-	-
WH1_k127_4608519_2	671143.DAMO_2737	3.132e-30	128.0	28IJY@1|root,2Z8KS@2|Bacteria	2|Bacteria	S	CRISPR-associated protein GSU0053 (Cas_GSU0053)	-	-	-	ko:K19131	-	-	-	-	ko00000,ko02048	-	-	-	Cas_GSU0053
WH1_k127_4623662_2	379066.GAU_0128	0.0002451	48.0	COG0812@1|root,COG0812@2|Bacteria,1ZSMJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
WH1_k127_4623662_0	926569.ANT_23400	1.804e-125	416.0	COG0773@1|root,COG0773@2|Bacteria,2G5J4@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WH1_k127_4624788_0	765420.OSCT_3176	1.77e-112	366.0	COG2317@1|root,COG2317@2|Bacteria,2G7UQ@200795|Chloroflexi,37518@32061|Chloroflexia	32061|Chloroflexia	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
WH1_k127_4624788_1	298654.FraEuI1c_2978	1.077e-69	259.0	COG1432@1|root,COG1432@2|Bacteria,2I9HK@201174|Actinobacteria	201174|Actinobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
WH1_k127_4627229_0	448385.sce5107	1.254e-25	113.0	COG0745@1|root,COG1511@1|root,COG2203@1|root,COG5002@1|root,COG0745@2|Bacteria,COG1511@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CVG@68525|delta/epsilon subdivisions,2X83E@28221|Deltaproteobacteria,2Z3K4@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
WH1_k127_4627229_3	1123368.AUIS01000006_gene676	4.719e-15	79.0	2C12A@1|root,33B7C@2|Bacteria,1NMUW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4627229_2	1242864.D187_006920	1.362e-16	84.0	COG3682@1|root,COG3682@2|Bacteria,1N6UP@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4639941_0	926569.ANT_11800	6.192e-74	273.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
WH1_k127_4639941_1	756067.MicvaDRAFT_4728	1.689e-12	77.0	COG2208@1|root,COG4191@1|root,COG2208@2|Bacteria,COG4191@2|Bacteria,1G160@1117|Cyanobacteria,1H75U@1150|Oscillatoriales	1117|Cyanobacteria	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	CHASE2,HAMP,SpoIIE,dCache_1
WH1_k127_4643352_0	383372.Rcas_2542	7.944e-64	223.0	2F76J@1|root,33ZMZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4643352_3	643473.KB235930_gene2748	5.12e-25	110.0	COG2405@1|root,COG2405@2|Bacteria,1G52J@1117|Cyanobacteria,1HPZ5@1161|Nostocales	1117|Cyanobacteria	S	Domain of unknown function (DUF3368)	-	-	-	ko:K07066	-	-	-	-	ko00000	-	-	-	DUF3368
WH1_k127_4643352_1	1541065.JRFE01000025_gene1986	1.421e-42	160.0	COG1487@1|root,COG1487@2|Bacteria,1G6X0@1117|Cyanobacteria,3VNGY@52604|Pleurocapsales	1117|Cyanobacteria	S	PIN domain	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
WH1_k127_4643352_2	102129.Lepto7375DRAFT_6474	2.679e-25	109.0	COG4456@1|root,COG4456@2|Bacteria,1G95Y@1117|Cyanobacteria,1HDTI@1150|Oscillatoriales	1117|Cyanobacteria	S	Virulence associated protein B	vapB	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
WH1_k127_4645435_0	63737.Npun_F1103	1.525e-27	124.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	BON,DUF4157,OmpA,PA14
WH1_k127_4648343_0	1394178.AWOO02000080_gene2095	1.767e-18	99.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4EG0F@85012|Streptosporangiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH1_k127_4653105_0	926569.ANT_12100	1.098e-124	411.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,OapA,OapA_N,Peptidase_M23
WH1_k127_4653105_3	552811.Dehly_1563	1.508e-25	111.0	COG2336@1|root,COG2336@2|Bacteria,2G9F5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM SpoVT AbrB domain protein	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
WH1_k127_4653105_1	324925.Ppha_0265	2.97e-43	163.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	chpA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
WH1_k127_4653105_2	926569.ANT_10880	1.368e-37	158.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,DUF1906,PG_binding_1,Peptidase_M15_4
WH1_k127_4653892_1	483219.LILAB_23265	2.996e-15	82.0	COG0457@1|root,COG1716@1|root,COG0457@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
WH1_k127_4653892_0	926569.ANT_15080	4.96e-22	104.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
WH1_k127_4653892_2	1089547.KB913013_gene3209	1.141e-14	81.0	2DMXT@1|root,32UAK@2|Bacteria,4NUIY@976|Bacteroidetes,47RHK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4653892_3	1463856.JOHY01000100_gene5867	0.0001944	45.0	COG4385@1|root,COG4385@2|Bacteria,2HG1T@201174|Actinobacteria	201174|Actinobacteria	S	TIGRFAM phage tail protein	-	-	-	-	-	-	-	-	-	-	-	-	Tail_P2_I
WH1_k127_4660341_1	926569.ANT_15670	5.547e-75	273.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_15670|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4660341_0	926550.CLDAP_32590	2.475e-75	256.0	COG1349@1|root,COG2865@1|root,COG1349@2|Bacteria,COG2865@2|Bacteria,2G7JP@200795|Chloroflexi	2|Bacteria	K	PFAM AAA-4 family protein	-	-	3.6.4.12	ko:K02444,ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	AlbA_2,DUF1670,DeoRC,HATPase_c_4,HTH_DeoR
WH1_k127_4673365_5	926569.ANT_10060	1.166e-22	100.0	COG0089@1|root,COG0089@2|Bacteria,2G73T@200795|Chloroflexi	200795|Chloroflexi	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
WH1_k127_4673365_0	926569.ANT_10070	7.951e-136	440.0	COG0090@1|root,COG0090@2|Bacteria,2G65E@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
WH1_k127_4673365_3	926569.ANT_10080	6.963e-45	164.0	COG0185@1|root,COG0185@2|Bacteria,2G6US@200795|Chloroflexi	200795|Chloroflexi	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
WH1_k127_4673365_4	926569.ANT_10090	4.048e-37	142.0	COG0091@1|root,COG0091@2|Bacteria,2G6ZQ@200795|Chloroflexi	200795|Chloroflexi	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
WH1_k127_4673365_1	926569.ANT_10100	1.586e-83	282.0	COG0092@1|root,COG0092@2|Bacteria,2G691@200795|Chloroflexi	200795|Chloroflexi	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
WH1_k127_4673365_2	926569.ANT_10110	1.459e-58	206.0	COG0197@1|root,COG0197@2|Bacteria,2G6NA@200795|Chloroflexi	200795|Chloroflexi	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
WH1_k127_4673365_6	926569.ANT_10120	5.512e-13	71.0	COG0255@1|root,COG0255@2|Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
WH1_k127_4673735_1	485913.Krac_6355	1.484e-50	187.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
WH1_k127_4673735_0	1382304.JNIL01000001_gene1268	2.065e-59	221.0	COG0675@1|root,COG0675@2|Bacteria,1UZNC@1239|Firmicutes,4HF5F@91061|Bacilli	91061|Bacilli	L	TIGRFAM transposase, IS605 OrfB	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
WH1_k127_4673735_2	1437608.BBIA_2445	6.245e-46	175.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4D00I@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234,HTH_IclR
WH1_k127_4678497_0	926569.ANT_09640	2.558e-149	479.0	COG0216@1|root,COG0216@2|Bacteria,2G5UD@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WH1_k127_4678497_1	1128421.JAGA01000002_gene196	2.104e-52	200.0	COG2890@1|root,COG2890@2|Bacteria,2NPDN@2323|unclassified Bacteria	2|Bacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
WH1_k127_4678497_2	1121405.dsmv_1567	2.189e-05	53.0	2BWVJ@1|root,33YN1@2|Bacteria,1NXTC@1224|Proteobacteria,430BZ@68525|delta/epsilon subdivisions,2WVZK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_46972_4	926550.CLDAP_01430	2.181e-10	63.0	COG2010@1|root,COG2010@2|Bacteria,2G9TS@200795|Chloroflexi	2|Bacteria	C	Cytochrome c	soxX	-	1.9.3.1	ko:K02275,ko:K17223	ko00190,ko00920,ko01100,ko01120,map00190,map00920,map01100,map01120	M00155,M00595	R00081,R10151	RC00016,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cytochrom_C
WH1_k127_46972_1	489825.LYNGBM3L_30140	4.249e-31	125.0	COG2442@1|root,COG2442@2|Bacteria,1G6VW@1117|Cyanobacteria,1HBPI@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
WH1_k127_46972_2	111780.Sta7437_0016	8.695e-25	107.0	COG4634@1|root,COG4634@2|Bacteria,1G84D@1117|Cyanobacteria,3VKI2@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
WH1_k127_46972_3	485913.Krac_5906	1.714e-12	74.0	COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
WH1_k127_46972_0	326427.Cagg_1254	3.843e-59	216.0	COG0354@1|root,COG0354@2|Bacteria,2G8ZM@200795|Chloroflexi,375KW@32061|Chloroflexia	32061|Chloroflexia	S	Aminomethyltransferase folate-binding domain	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
WH1_k127_4700940_0	1123255.JHYS01000002_gene2570	4.172e-157	501.0	COG1672@1|root,COG1672@2|Bacteria,1R8WG@1224|Proteobacteria,2VQHA@28216|Betaproteobacteria,4AJB5@80864|Comamonadaceae	28216|Betaproteobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4716575_1	118161.KB235922_gene4761	2.374e-26	114.0	COG0454@1|root,COG0456@2|Bacteria,1G7ME@1117|Cyanobacteria,3VK6H@52604|Pleurocapsales	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
WH1_k127_4716575_0	926550.CLDAP_00560	6.27e-86	288.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
WH1_k127_4723774_0	278957.ABEA03000151_gene4127	4.235e-91	319.0	COG2352@1|root,COG2352@2|Bacteria,46SIN@74201|Verrucomicrobia,3K7TR@414999|Opitutae	414999|Opitutae	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	-	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
WH1_k127_4723774_1	1396.DJ87_5114	1.555e-10	70.0	COG0477@1|root,COG2814@2|Bacteria,1V0M2@1239|Firmicutes,4HCQZ@91061|Bacilli,1ZQZS@1386|Bacillus	91061|Bacilli	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,MFS_2,MFS_3,Sugar_tr
WH1_k127_4725673_0	926569.ANT_25840	2.164e-86	295.0	COG0484@1|root,COG0484@2|Bacteria,2G61V@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock protein DnaJ domain protein	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
WH1_k127_4729679_0	1158756.AQXQ01000011_gene892	1.043e-05	49.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1WWQE@135613|Chromatiales	135613|Chromatiales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
WH1_k127_4729679_1	314254.OA2633_12345	0.0001986	52.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WH1_k127_4737370_1	1536773.R70331_30280	6.911e-12	67.0	COG1028@1|root,COG1028@2|Bacteria,1U2GS@1239|Firmicutes,4H9R9@91061|Bacilli,26QGX@186822|Paenibacillaceae	91061|Bacilli	IQ	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG1	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WH1_k127_4737370_0	1128421.JAGA01000002_gene855	1.415e-163	527.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
WH1_k127_4744290_1	1304874.JAFY01000002_gene574	1.048e-53	197.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
WH1_k127_4744290_0	1047013.AQSP01000134_gene1338	3.233e-103	353.0	COG5598@1|root,COG5598@2|Bacteria,2NQTC@2323|unclassified Bacteria	2|Bacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
WH1_k127_4744290_2	316274.Haur_1215	5.587e-40	151.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K02030,ko:K03407,ko:K07679,ko:K11443,ko:K13924	ko02020,ko02030,ko04112,ko05133,map02020,map02030,map04112,map05133	M00236,M00477,M00506,M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035	3.A.1.3	-	-	CHASE3,HATPase_c,HisKA,NMT1,PAS_3,PAS_9,Response_reg,SBP_bac_3
WH1_k127_475829_3	644968.DFW101_1421	3.872e-05	54.0	COG0500@1|root,COG2226@2|Bacteria,1RKJ7@1224|Proteobacteria,42T77@68525|delta/epsilon subdivisions,2WT2E@28221|Deltaproteobacteria,2M8S2@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WH1_k127_475829_0	575540.Isop_3294	1.734e-127	413.0	COG2189@1|root,COG2189@2|Bacteria,2J0J2@203682|Planctomycetes	203682|Planctomycetes	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
WH1_k127_475829_1	926569.ANT_17850	9.563e-24	104.0	COG0378@1|root,COG0378@2|Bacteria,2G6EP@200795|Chloroflexi	200795|Chloroflexi	KO	Hydrogenase accessory protein HypB	hypB	-	-	ko:K03189,ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
WH1_k127_4758953_1	926569.ANT_25850	3.63e-24	106.0	COG0265@1|root,COG0265@2|Bacteria,2G6KG@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WH1_k127_4758953_0	1128421.JAGA01000003_gene2824	1.192e-74	256.0	COG1488@1|root,COG1488@2|Bacteria,2NNUE@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	iYO844.BSU31750	NAPRTase
WH1_k127_4762890_0	1128421.JAGA01000002_gene1152	2.629e-37	157.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2NR6B@2323|unclassified Bacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH1_k127_476323_1	1255043.TVNIR_2894	2.485e-44	167.0	COG0500@1|root,COG2226@2|Bacteria,1MYPU@1224|Proteobacteria,1SZ13@1236|Gammaproteobacteria,1X22Q@135613|Chromatiales	135613|Chromatiales	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WH1_k127_476323_0	765420.OSCT_3118	1.316e-115	382.0	COG0215@1|root,COG4242@1|root,COG0215@2|Bacteria,COG4242@2|Bacteria,2G6C3@200795|Chloroflexi	200795|Chloroflexi	PQ	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4763773_0	1121930.AQXG01000002_gene1952	5.628e-138	460.0	COG1042@1|root,COG1042@2|Bacteria,4NFTI@976|Bacteroidetes,1IVTU@117747|Sphingobacteriia	976|Bacteroidetes	C	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
WH1_k127_4763773_1	756499.Desde_2250	1.899e-52	195.0	COG1410@1|root,COG1410@2|Bacteria,1VRVS@1239|Firmicutes,25EJA@186801|Clostridia,26050@186807|Peptococcaceae	186801|Clostridia	E	PFAM Pterin binding enzyme	acsE	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
WH1_k127_477282_1	502025.Hoch_4798	5.217e-09	64.0	28PPK@1|root,2ZCC0@2|Bacteria,1RBNQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_477282_0	864702.OsccyDRAFT_2878	1.872e-57	220.0	COG2114@1|root,COG2114@2|Bacteria,1G53R@1117|Cyanobacteria,1HFDP@1150|Oscillatoriales	1117|Cyanobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
WH1_k127_4776819_0	765420.OSCT_2987	2.157e-75	276.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,376QI@32061|Chloroflexia	32061|Chloroflexia	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc
WH1_k127_4805531_0	926569.ANT_16300	4.866e-95	319.0	COG0345@1|root,COG0345@2|Bacteria,2G5QD@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
WH1_k127_4805531_1	926569.ANT_13770	1.429e-94	314.0	COG0056@1|root,COG0056@2|Bacteria,2G5YQ@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
WH1_k127_4824721_5	1192034.CAP_3742	1.693e-10	61.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,42M56@68525|delta/epsilon subdivisions,2WJ8W@28221|Deltaproteobacteria,2YYDJ@29|Myxococcales	28221|Deltaproteobacteria	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WH1_k127_4824721_1	1128421.JAGA01000002_gene1517	4.96e-171	545.0	COG3844@1|root,COG3844@2|Bacteria,2NS52@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class-V	kynU	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
WH1_k127_4824721_2	203124.Tery_2811	3.051e-25	118.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria,1H84Z@1150|Oscillatoriales	1117|Cyanobacteria	U	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
WH1_k127_4824721_3	1163617.SCD_n02965	6.446e-17	92.0	COG0223@1|root,COG0223@2|Bacteria,1PHQ5@1224|Proteobacteria,2W46P@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Formyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_N
WH1_k127_4824721_0	926569.ANT_00850	3.108e-212	670.0	COG1350@1|root,COG1350@2|Bacteria,2G5YY@200795|Chloroflexi	200795|Chloroflexi	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WH1_k127_4824721_4	554065.XP_005849811.1	1.682e-15	77.0	COG1932@1|root,KOG2790@2759|Eukaryota,37IGE@33090|Viridiplantae,34JBS@3041|Chlorophyta	3041|Chlorophyta	E	Aminotransferase class-V	-	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
WH1_k127_4836692_4	340177.Cag_0267	2.158e-22	100.0	COG4226@1|root,COG4226@2|Bacteria	2|Bacteria	K	protein encoded in hypervariable junctions of pilus gene clusters	-	-	-	-	-	-	-	-	-	-	-	-	HicB
WH1_k127_4836692_3	395961.Cyan7425_4601	4.05e-45	168.0	COG1569@1|root,COG1569@2|Bacteria,1G7HY@1117|Cyanobacteria,3KKCM@43988|Cyanothece	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
WH1_k127_4836692_1	926569.ANT_10540	6.017e-67	239.0	COG0711@1|root,COG0712@1|root,COG0711@2|Bacteria,COG0712@2|Bacteria,2G76T@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
WH1_k127_4836692_5	926569.ANT_10530	4.929e-13	73.0	COG0636@1|root,COG0636@2|Bacteria,2G72D@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
WH1_k127_4836692_2	926569.ANT_10520	5.688e-66	239.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi	200795|Chloroflexi	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
WH1_k127_4836692_0	926569.ANT_10480	2.163e-124	411.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
WH1_k127_4872448_1	420324.KI912055_gene5732	4.644e-05	54.0	COG3712@1|root,COG3712@2|Bacteria,1R05P@1224|Proteobacteria,2TYK5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
WH1_k127_4872448_0	635013.TherJR_2805	3.481e-49	199.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1TQIK@1239|Firmicutes,249Y6@186801|Clostridia,267E8@186807|Peptococcaceae	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
WH1_k127_4873617_1	926569.ANT_28690	3.351e-20	94.0	COG3868@1|root,COG3868@2|Bacteria,2G983@200795|Chloroflexi	200795|Chloroflexi	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
WH1_k127_4873617_0	926569.ANT_10870	3.125e-225	723.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WH1_k127_4897152_1	926550.CLDAP_11290	3.688e-103	341.0	COG0411@1|root,COG0411@2|Bacteria,2G5W6@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WH1_k127_4897152_0	1449080.JQMV01000003_gene508	9.273e-104	341.0	COG0410@1|root,COG0410@2|Bacteria,1WJM5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type branched-chain amino acid transport systems ATPase component	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
WH1_k127_4897152_2	316274.Haur_0690	2.749e-23	112.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,Rhomboid,TPR_16,TPR_19,TPR_8
WH1_k127_4899675_1	926569.ANT_18490	8.799e-21	93.0	COG0785@1|root,COG0785@2|Bacteria,2G6V3@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
WH1_k127_4899675_0	926569.ANT_18500	5.308e-65	235.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
WH1_k127_4907648_2	1121468.AUBR01000012_gene2571	9.234e-34	140.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,24PNN@186801|Clostridia,42JDW@68295|Thermoanaerobacterales	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WH1_k127_4907648_0	518766.Rmar_1588	4.789e-47	177.0	COG0009@1|root,COG0009@2|Bacteria,4NF5U@976|Bacteroidetes,1FIY9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua5	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
WH1_k127_4907648_3	1385513.N780_01300	6.622e-06	55.0	2DPKD@1|root,332HI@2|Bacteria,1VHUB@1239|Firmicutes,4IS0F@91061|Bacilli,2YAPK@289201|Pontibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4907648_1	1382356.JQMP01000003_gene2174	1.612e-36	144.0	COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi,27XSF@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH1_k127_4923440_1	1408422.JHYF01000016_gene32	5.421e-43	164.0	COG0454@1|root,COG0456@2|Bacteria,1V2CK@1239|Firmicutes,24KFX@186801|Clostridia,36MGM@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WH1_k127_4923440_0	926569.ANT_25930	5.202e-49	195.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,VanY,YkuD
WH1_k127_4924756_0	926569.ANT_11780	9.297e-28	130.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WH1_k127_4925742_2	926569.ANT_29900	5.466e-74	256.0	COG4012@1|root,COG4012@2|Bacteria,2G6IF@200795|Chloroflexi	200795|Chloroflexi	S	Putative pyruvate format-lyase activating enzyme (DUF1786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1786
WH1_k127_4925742_0	316274.Haur_3267	6.889e-201	646.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi,374Z6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
WH1_k127_4925742_3	316274.Haur_3268	8.35e-30	133.0	COG0517@1|root,COG0517@2|Bacteria,2G9A7@200795|Chloroflexi	200795|Chloroflexi	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WH1_k127_4925742_1	1382306.JNIM01000001_gene3438	3.727e-90	309.0	COG2355@1|root,COG2355@2|Bacteria,2G6FQ@200795|Chloroflexi	200795|Chloroflexi	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
WH1_k127_4934811_2	926569.ANT_09910	1.069e-23	104.0	COG0682@1|root,COG0682@2|Bacteria,2G6QJ@200795|Chloroflexi	200795|Chloroflexi	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WH1_k127_4934811_1	926569.ANT_09900	8.901e-57	204.0	COG0558@1|root,COG0558@2|Bacteria,2G6ZT@200795|Chloroflexi	200795|Chloroflexi	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WH1_k127_4934811_0	316274.Haur_3367	9.84e-66	225.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,374ZW@32061|Chloroflexia	32061|Chloroflexia	I	Myo-inositol-1-phosphate synthase, GAPDH domain protein	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
WH1_k127_4940230_0	1173028.ANKO01000155_gene4502	8.031e-10	70.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7DY@1150|Oscillatoriales	1117|Cyanobacteria	A	Wd40 repeat-containing protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_35,Peptidase_C14,TIR_2,TPR_8,WD40
WH1_k127_4946899_1	926550.CLDAP_14270	1.865e-88	297.0	COG0410@1|root,COG0410@2|Bacteria,2G654@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
WH1_k127_4946899_2	926550.CLDAP_14280	1.236e-72	263.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WH1_k127_4946899_0	926550.CLDAP_14290	1.816e-122	402.0	COG4177@1|root,COG4177@2|Bacteria,2G6HP@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WH1_k127_4946899_3	926550.CLDAP_14300	6.344e-26	109.0	COG0559@1|root,COG0559@2|Bacteria,2G6M5@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WH1_k127_4951205_3	796945.HMPREF1145_1503	6.027e-13	71.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,2PRF1@265975|Oribacterium	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
WH1_k127_4951205_0	383372.Rcas_3193	9.8e-150	481.0	COG0667@1|root,COG0667@2|Bacteria,2G6BF@200795|Chloroflexi,377XY@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WH1_k127_4951205_2	1122927.KB895415_gene4390	1.275e-25	118.0	COG1051@1|root,COG3981@1|root,COG1051@2|Bacteria,COG3981@2|Bacteria,1V1C4@1239|Firmicutes,4HG6C@91061|Bacilli,26XIE@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
WH1_k127_4951205_4	1297865.APJD01000001_gene5819	1.641e-10	75.0	COG3391@1|root,COG3391@2|Bacteria,1MXJJ@1224|Proteobacteria,2TTH6@28211|Alphaproteobacteria,3JUP4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Cytochrome D1 heme domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase,NHL
WH1_k127_4951205_1	247490.KSU1_B0116	1.926e-28	134.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4964265_1	926550.CLDAP_04490	0.0002104	54.0	COG0823@1|root,COG3103@1|root,COG0823@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	NLPC_P60,Rick_17kDa_Anti,SH3_3
WH1_k127_4964265_0	926550.CLDAP_35480	5.193e-15	89.0	COG3103@1|root,COG3693@1|root,COG3103@2|Bacteria,COG3693@2|Bacteria,COG4991@2|Bacteria,2GBGU@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_42
WH1_k127_4968289_0	720554.Clocl_3341	4.64e-200	630.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGVP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WH1_k127_4968289_2	1198452.Jab_2c08630	6.086e-62	238.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,2VNBH@28216|Betaproteobacteria,476U3@75682|Oxalobacteraceae	1224|Proteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
WH1_k127_4968289_3	1521187.JPIM01000026_gene1160	2.176e-24	120.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WH1_k127_4968289_5	1123013.AUIC01000005_gene1377	4.497e-12	70.0	COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria,4FPR4@85023|Microbacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
WH1_k127_4968289_4	926569.ANT_19040	2.45e-16	82.0	2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4968289_1	926569.ANT_29620	2.193e-162	518.0	COG1180@1|root,COG1180@2|Bacteria,2G6B2@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WH1_k127_4976864_0	326427.Cagg_0338	4.271e-131	429.0	COG0834@1|root,COG0834@2|Bacteria,2G7RH@200795|Chloroflexi,376Y9@32061|Chloroflexia	32061|Chloroflexia	ET	extracellular solute-binding protein, family 3	-	-	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
WH1_k127_4976864_2	926550.CLDAP_08220	1.35e-83	297.0	COG4597@1|root,COG4597@2|Bacteria	2|Bacteria	P	amino acid transport	bgtB	-	-	ko:K09970,ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
WH1_k127_4976864_3	1121441.AUCX01000025_gene1670	2.547e-71	259.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,42PDT@68525|delta/epsilon subdivisions,2WKER@28221|Deltaproteobacteria,2MAP8@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
WH1_k127_4976864_1	1128421.JAGA01000002_gene1955	6.313e-119	387.0	COG1126@1|root,COG1126@2|Bacteria,2NPH5@2323|unclassified Bacteria	2|Bacteria	E	ATPases associated with a variety of cellular activities	aapP	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.6.3.21	ko:K02028,ko:K02030,ko:K09972	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	iJN746.PP_1300,iJN746.PP_3597	ABC_tran
WH1_k127_497841_0	497964.CfE428DRAFT_0194	5.968e-210	661.0	COG4284@1|root,COG4284@2|Bacteria,46SCH@74201|Verrucomicrobia	74201|Verrucomicrobia	H	UTP--glucose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGP
WH1_k127_497841_1	497964.CfE428DRAFT_0193	2.028e-78	266.0	COG1210@1|root,COG1210@2|Bacteria,46S5P@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Utp--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WH1_k127_4979997_0	368408.Tpen_1400	4.575e-79	275.0	COG1131@1|root,arCOG00194@2157|Archaea,2XPS7@28889|Crenarchaeota	28889|Crenarchaeota	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WH1_k127_4979997_1	1006006.Mcup_1340	6.479e-06	57.0	COG0842@1|root,arCOG01465@2157|Archaea,2XQB0@28889|Crenarchaeota	28889|Crenarchaeota	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
WH1_k127_4982876_0	2002.JOEQ01000017_gene7796	4.475e-26	126.0	COG1404@1|root,COG1404@2|Bacteria,2HEJ5@201174|Actinobacteria,4EHUI@85012|Streptosporangiales	201174|Actinobacteria	O	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Malectin,Peptidase_S8
WH1_k127_4982876_1	309798.COPRO5265_1583	4.22e-09	70.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,42G7V@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	ko:K13274,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,CW_binding_2,Peptidase_S8,SLH
WH1_k127_4987031_1	504728.K649_13530	2.342e-123	402.0	COG0215@1|root,COG0215@2|Bacteria,1WIEP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
WH1_k127_4987031_0	926569.ANT_30570	1.708e-125	411.0	COG4956@1|root,COG4956@2|Bacteria,2G5YK@200795|Chloroflexi	200795|Chloroflexi	S	SMART Nucleotide binding protein, PINc	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
WH1_k127_4987031_2	926569.ANT_00970	3.201e-62	218.0	COG1066@1|root,COG1066@2|Bacteria,2G5TE@200795|Chloroflexi	200795|Chloroflexi	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
WH1_k127_4997398_0	926569.ANT_19070	4.376e-194	612.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi	200795|Chloroflexi	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
WH1_k127_4997398_1	255470.cbdbA1740	6.661e-54	199.0	COG1974@1|root,COG1974@2|Bacteria,2G6NC@200795|Chloroflexi,34CY4@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
WH1_k127_4997398_3	926569.ANT_03880	2.362e-39	152.0	COG5615@1|root,COG5615@2|Bacteria	2|Bacteria	L	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CopD
WH1_k127_4997398_5	867845.KI911784_gene1066	4.73e-09	68.0	COG0457@1|root,COG0457@2|Bacteria,2GA74@200795|Chloroflexi,375MU@32061|Chloroflexia	32061|Chloroflexia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_4997398_4	1033806.HTIA_1300	5.506e-16	84.0	COG0456@1|root,arCOG00833@2157|Archaea,2Y0G0@28890|Euryarchaeota,23WBW@183963|Halobacteria	183963|Halobacteria	K	COG0456 Acetyltransferases	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
WH1_k127_4997398_2	926569.ANT_03840	1.337e-50	194.0	COG0359@1|root,COG0359@2|Bacteria,2G6V2@200795|Chloroflexi	200795|Chloroflexi	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
WH1_k127_5009658_5	864051.BurJ1DRAFT_0558	4.72e-16	83.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,1KKP8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
WH1_k127_5009658_2	1120746.CCNL01000017_gene2423	1.107e-90	310.0	COG1597@1|root,COG1597@2|Bacteria	2|Bacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
WH1_k127_5009658_3	1120746.CCNL01000017_gene2422	4.282e-65	231.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	pgpB1	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
WH1_k127_5009658_4	1121472.AQWN01000005_gene2522	1.093e-16	91.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,261TC@186807|Peptococcaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WH1_k127_5009658_0	926569.ANT_07760	1.42e-128	424.0	COG0388@1|root,COG0388@2|Bacteria,2G8XD@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
WH1_k127_5009658_1	926569.ANT_07770	2.813e-120	392.0	COG0171@1|root,COG0171@2|Bacteria,2G6X3@200795|Chloroflexi	200795|Chloroflexi	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
WH1_k127_5017348_0	1128421.JAGA01000002_gene455	4.906e-76	271.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
WH1_k127_5017348_2	926569.ANT_28280	2.357e-30	121.0	COG0361@1|root,COG0361@2|Bacteria,2G7AQ@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
WH1_k127_5017348_1	324602.Caur_1839	2.412e-53	194.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi,374X2@32061|Chloroflexia	32061|Chloroflexia	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
WH1_k127_5022095_0	926569.ANT_00970	4.103e-83	289.0	COG1066@1|root,COG1066@2|Bacteria,2G5TE@200795|Chloroflexi	200795|Chloroflexi	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
WH1_k127_5022095_1	765910.MARPU_16705	2.875e-21	100.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,1S61Y@1236|Gammaproteobacteria,1WZ34@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0250 family	-	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
WH1_k127_5024757_0	316274.Haur_3042	2.1e-128	421.0	COG1600@1|root,COG1600@2|Bacteria,2G6A0@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S double cluster binding domain	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Dehalogenase,Fer4_16,HEAT_2
WH1_k127_5024757_1	380703.AHA_3814	3.865e-126	409.0	COG0687@1|root,COG0687@2|Bacteria,1NKD7@1224|Proteobacteria,1RQPF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Spermidine putrescine ABC transporter substrate-binding protein	ydcS	GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	iECNA114_1301.ECNA114_1576,iECSF_1327.ECSF_1364,iEcHS_1320.EcHS_A1524	SBP_bac_8
WH1_k127_5032272_4	324602.Caur_0107	5.33e-10	64.0	COG3944@1|root,COG3944@2|Bacteria,2G9GX@200795|Chloroflexi,375NI@32061|Chloroflexia	32061|Chloroflexia	M	PFAM lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
WH1_k127_5032272_2	357808.RoseRS_4042	9.909e-63	224.0	COG0489@1|root,COG0489@2|Bacteria,2G5WM@200795|Chloroflexi,375EN@32061|Chloroflexia	32061|Chloroflexia	D	TIGRFAM capsular exopolysaccharide family	-	-	2.7.10.2	ko:K08253	-	-	-	-	ko00000,ko01000	-	-	-	CbiA,ParA
WH1_k127_5032272_0	926550.CLDAP_01250	8.276e-161	523.0	COG1209@1|root,COG1209@2|Bacteria,2G6MR@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WH1_k127_5032272_1	324602.Caur_2312	5.507e-140	452.0	COG1088@1|root,COG1088@2|Bacteria,2G5KR@200795|Chloroflexi,375GP@32061|Chloroflexia	32061|Chloroflexia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WH1_k127_5032272_3	926550.CLDAP_17030	8.849e-35	150.0	COG0823@1|root,COG0823@2|Bacteria,2G8W2@200795|Chloroflexi	200795|Chloroflexi	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Big_5,PD40
WH1_k127_5034931_3	926550.CLDAP_07710	8.528e-30	120.0	COG0845@1|root,COG0845@2|Bacteria,2G93B@200795|Chloroflexi	200795|Chloroflexi	MV	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
WH1_k127_5034931_0	926550.CLDAP_07700	2.297e-103	344.0	COG1131@1|root,COG1131@2|Bacteria,2G7Q5@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH1_k127_5034931_1	264732.Moth_1900	2.714e-90	308.0	COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,25B35@186801|Clostridia,42FFN@68295|Thermoanaerobacterales	186801|Clostridia	V	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH1_k127_5034931_2	671143.DAMO_2937	4.397e-62	226.0	COG0784@1|root,COG3290@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,2NS4C@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SPOB_a
WH1_k127_5048572_2	926569.ANT_15290	4.563e-26	108.0	COG0711@1|root,COG0711@2|Bacteria,2G79J@200795|Chloroflexi	200795|Chloroflexi	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_5048572_1	926569.ANT_15280	1.179e-61	216.0	COG0669@1|root,COG0669@2|Bacteria,2G6NZ@200795|Chloroflexi	200795|Chloroflexi	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WH1_k127_5048572_0	309801.trd_0084	8.123e-219	704.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi,27XT4@189775|Thermomicrobia	189775|Thermomicrobia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WH1_k127_5051362_0	383372.Rcas_2574	1.915e-25	123.0	COG1572@1|root,COG3386@1|root,COG1572@2|Bacteria,COG3386@2|Bacteria,2G9CG@200795|Chloroflexi,374U7@32061|Chloroflexia	32061|Chloroflexia	G	LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,Laminin_G_3
WH1_k127_5077828_0	926569.ANT_10570	3.999e-135	441.0	COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi	200795|Chloroflexi	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WH1_k127_5077828_1	1122927.KB895418_gene2753	2.451e-27	115.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli,26Y58@186822|Paenibacillaceae	91061|Bacilli	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
WH1_k127_509116_1	234267.Acid_7895	2.753e-58	211.0	28MCK@1|root,2ZAQP@2|Bacteria,3Y41I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_509116_0	234267.Acid_7894	6.715e-99	334.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
WH1_k127_509116_2	234267.Acid_0431	1.312e-53	194.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	57723|Acidobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
WH1_k127_5101664_0	762903.Pedsa_1184	1.403e-07	58.0	28IIY@1|root,2Z8JY@2|Bacteria,4NHQ5@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_5104840_0	926569.ANT_30000	2.861e-194	621.0	COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V,Smr
WH1_k127_5114636_0	309799.DICTH_1684	1.868e-58	224.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
WH1_k127_5115215_2	1382356.JQMP01000003_gene2195	2.927e-86	296.0	COG1116@1|root,COG1116@2|Bacteria,2G6BU@200795|Chloroflexi,27YRQ@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WH1_k127_5115215_1	357808.RoseRS_0670	7.385e-89	315.0	COG0715@1|root,COG0715@2|Bacteria,2G71V@200795|Chloroflexi,376VQ@32061|Chloroflexia	32061|Chloroflexia	P	PFAM NMT1 THI5 like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
WH1_k127_5115215_3	2074.JNYD01000023_gene1321	9.255e-70	245.0	COG0600@1|root,COG0600@2|Bacteria,2HMR9@201174|Actinobacteria,4EENW@85010|Pseudonocardiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15599	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	BPD_transp_1
WH1_k127_5115215_5	1499967.BAYZ01000184_gene4564	1.088e-43	166.0	COG1564@1|root,COG1564@2|Bacteria,2NPUG@2323|unclassified Bacteria	2|Bacteria	H	Thiamin pyrophosphokinase, vitamin B1 binding domain	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
WH1_k127_5115215_4	1254432.SCE1572_15570	6.23e-67	254.0	COG0664@1|root,COG3264@1|root,COG0664@2|Bacteria,COG3264@2|Bacteria,1QX62@1224|Proteobacteria,42S57@68525|delta/epsilon subdivisions,2WNY0@28221|Deltaproteobacteria,2YVPP@29|Myxococcales	28221|Deltaproteobacteria	MT	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
WH1_k127_5115215_0	926569.ANT_20890	8.701e-95	315.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
WH1_k127_5115621_5	935948.KE386494_gene656	3.514e-06	54.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes,25BB9@186801|Clostridia,42G9S@68295|Thermoanaerobacterales	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
WH1_k127_5115621_1	316274.Haur_4686	3.076e-20	96.0	COG3688@1|root,COG3688@2|Bacteria,2G95S@200795|Chloroflexi,375WR@32061|Chloroflexia	32061|Chloroflexia	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
WH1_k127_5115621_6	1449338.JQLU01000005_gene3631	0.0001254	53.0	COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,1VG53@1239|Firmicutes,4HNHM@91061|Bacilli	91061|Bacilli	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	3.2.1.17	ko:K01185	-	-	-	-	ko00000,ko01000	-	-	-	CHAP,Glucosaminidase,LysM,SH3_5
WH1_k127_5115621_2	926569.ANT_01330	3.167e-19	99.0	COG2333@1|root,COG2333@2|Bacteria	2|Bacteria	N	competence protein COMEC	ycaI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
WH1_k127_5115621_3	1382306.JNIM01000001_gene1055	5.109e-14	78.0	2DRW3@1|root,33DCW@2|Bacteria,2G7E0@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF1992)	-	-	-	ko:K19373	-	-	-	-	ko00000,ko03110	-	-	-	DUF1992
WH1_k127_5115621_0	926569.ANT_01340	4.422e-95	315.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
WH1_k127_5130313_4	926569.ANT_30110	2.48e-56	201.0	COG0860@1|root,COG0860@2|Bacteria,2G7IE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
WH1_k127_5130313_8	489825.LYNGBM3L_44580	1.13e-08	59.0	COG1376@1|root,COG1376@2|Bacteria,1G4ZS@1117|Cyanobacteria,1HAVT@1150|Oscillatoriales	1117|Cyanobacteria	S	ErfK YbiS YcfS YnhG	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
WH1_k127_5130313_1	1173026.Glo7428_2203	1.782e-72	279.0	COG0642@1|root,COG2197@1|root,COG2203@1|root,COG2197@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07716	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_4,Response_reg
WH1_k127_5130313_5	867845.KI911784_gene1764	7.072e-50	189.0	COG0745@1|root,COG0745@2|Bacteria,2G8W7@200795|Chloroflexi,375AC@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WH1_k127_5130313_0	316274.Haur_3458	3.797e-104	372.0	COG2203@1|root,COG2204@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	phoR	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K02484,ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
WH1_k127_5130313_7	1201288.M900_0660	3.424e-10	73.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MZX@68525|delta/epsilon subdivisions,2WMCT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
WH1_k127_5130313_3	316274.Haur_1217	5.629e-62	237.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WH1_k127_5130313_2	163908.KB235896_gene4212	1.266e-68	246.0	COG0715@1|root,COG0715@2|Bacteria,1G4RQ@1117|Cyanobacteria	1117|Cyanobacteria	P	COGs COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
WH1_k127_5130313_6	756067.MicvaDRAFT_4728	8.195e-32	138.0	COG2208@1|root,COG4191@1|root,COG2208@2|Bacteria,COG4191@2|Bacteria,1G160@1117|Cyanobacteria,1H75U@1150|Oscillatoriales	1117|Cyanobacteria	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	CHASE2,HAMP,SpoIIE,dCache_1
WH1_k127_5137780_2	1045855.DSC_11355	2.715e-13	74.0	2EGCD@1|root,33A46@2|Bacteria,1NMIX@1224|Proteobacteria,1SIUN@1236|Gammaproteobacteria,1X8EM@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
WH1_k127_5137780_0	926569.ANT_23560	3.19e-64	225.0	2DM5T@1|root,31U0Y@2|Bacteria,2G78W@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
WH1_k127_5137780_1	326427.Cagg_1509	7.457e-31	129.0	2E3IJ@1|root,32YH0@2|Bacteria,2G7AM@200795|Chloroflexi,375QX@32061|Chloroflexia	32061|Chloroflexia	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
WH1_k127_5149629_0	926569.ANT_15990	4.233e-132	430.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi	200795|Chloroflexi	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
WH1_k127_5170072_0	909663.KI867150_gene97	1.329e-138	453.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MQ8Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
WH1_k127_5170072_2	1000565.METUNv1_01804	6.237e-07	60.0	COG0664@1|root,COG2146@1|root,COG0664@2|Bacteria,COG2146@2|Bacteria,1R7VX@1224|Proteobacteria,2WF8C@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
WH1_k127_5170072_1	868131.MSWAN_1393	1.878e-24	108.0	COG1245@1|root,COG1810@1|root,arCOG00187@2157|Archaea,arCOG02468@2157|Archaea,2XU42@28890|Euryarchaeota	28890|Euryarchaeota	S	Domain of unknown function	-	GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046073,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF166,Fer4
WH1_k127_5175483_0	316274.Haur_1217	1.723e-147	476.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WH1_k127_5175483_1	316274.Haur_1218	9.556e-95	317.0	COG0498@1|root,COG0784@1|root,COG0498@2|Bacteria,COG0784@2|Bacteria,2G66Y@200795|Chloroflexi,375PP@32061|Chloroflexia	2|Bacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733,ko:K22010	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018,M00839	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	HATPase_c,HisKA,PALP,Response_reg
WH1_k127_5190746_1	522306.CAP2UW1_1434	1.796e-18	99.0	COG0500@1|root,COG2226@2|Bacteria,1QXSJ@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WH1_k127_5190746_0	709986.Deima_0817	5.305e-45	171.0	COG1307@1|root,COG1307@2|Bacteria,1WIY0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WH1_k127_5191093_0	331678.Cphamn1_1346	1.524e-182	580.0	COG0433@1|root,COG0433@2|Bacteria,1FEIF@1090|Chlorobi	1090|Chlorobi	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
WH1_k127_5191093_1	765420.OSCT_2724	1.131e-70	257.0	COG1502@1|root,COG1502@2|Bacteria,2G8RC@200795|Chloroflexi,37519@32061|Chloroflexia	32061|Chloroflexia	I	PFAM phospholipase D Transphosphatidylase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
WH1_k127_5191093_2	649638.Trad_2759	1.715e-17	84.0	COG0483@1|root,COG0483@2|Bacteria,1WIZ7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
WH1_k127_5213898_2	326427.Cagg_3761	1.96e-06	59.0	COG1744@1|root,COG1744@2|Bacteria,2G6UB@200795|Chloroflexi,375H7@32061|Chloroflexia	32061|Chloroflexia	M	PFAM basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
WH1_k127_5213898_1	1121468.AUBR01000103_gene3098	1.906e-07	63.0	COG1669@1|root,COG1669@2|Bacteria,1VDI2@1239|Firmicutes,24P07@186801|Clostridia,42IJR@68295|Thermoanaerobacterales	186801|Clostridia	L	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
WH1_k127_5213898_0	357808.RoseRS_4092	1.236e-41	158.0	2EC5H@1|root,33648@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_5232441_1	1040986.ATYO01000001_gene1714	5.17e-11	75.0	COG0845@1|root,COG0845@2|Bacteria,1NJDF@1224|Proteobacteria,2TSZA@28211|Alphaproteobacteria,43JAU@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WH1_k127_5232441_0	1094508.Tsac_0333	1.433e-12	72.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,42FTY@68295|Thermoanaerobacterales	186801|Clostridia	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH1_k127_5238525_0	593907.Celgi_1447	7.328e-38	153.0	COG0454@1|root,COG0456@2|Bacteria,2I0BQ@201174|Actinobacteria,4F17M@85016|Cellulomonadaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WH1_k127_5238525_1	485913.Krac_9585	8.206e-21	101.0	COG0454@1|root,COG1246@1|root,COG0456@2|Bacteria,COG1246@2|Bacteria,2G8UQ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WH1_k127_5256757_0	1128421.JAGA01000002_gene372	4.519e-54	209.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,PTPS_related
WH1_k127_5256757_1	926550.CLDAP_01930	3.731e-41	174.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
WH1_k127_5256849_0	926569.ANT_23020	4.664e-109	378.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
WH1_k127_5256849_1	926569.ANT_23030	6.169e-74	271.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
WH1_k127_5256849_2	926569.ANT_30410	2.103e-19	91.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi	200795|Chloroflexi	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
WH1_k127_526_0	926554.KI912671_gene483	4.823e-114	379.0	COG2723@1|root,COG2723@2|Bacteria,1WIBW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glycosyl hydrolase family 1	-	-	3.2.1.21,3.2.1.86	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	-	R00026,R00839,R02558,R02887,R02985,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
WH1_k127_5262352_2	234267.Acid_6209	2.009e-23	104.0	COG0723@1|root,COG0723@2|Bacteria,3Y7YJ@57723|Acidobacteria	57723|Acidobacteria	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
WH1_k127_5262352_0	330214.NIDE3889	1.508e-69	248.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3J0Q6@40117|Nitrospirae	2|Bacteria	C	Cytochrome b/b6/petB	qcrC	-	-	ko:K00412,ko:K03888	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B,Cytochrome_CBB3
WH1_k127_5262352_1	929712.KI912613_gene1096	1.874e-28	123.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,2HDYV@201174|Actinobacteria,4CQSB@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b subunit of the bc	-	-	-	ko:K03888	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_C,Cytochrom_C,Cytochrome_CBB3
WH1_k127_5269923_0	479434.Sthe_2282	1.187e-123	417.0	COG2217@1|root,COG2217@2|Bacteria,2G5QF@200795|Chloroflexi,27YTH@189775|Thermomicrobia	189775|Thermomicrobia	P	E1-E2 ATPase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
WH1_k127_5269923_2	926569.ANT_25300	7.767e-72	252.0	COG2888@1|root,COG2888@2|Bacteria	2|Bacteria	J	peptidyl-tyrosine sulfation	ybeL	-	1.17.4.1,4.6.1.1	ko:K00525,ko:K01768	ko00230,ko00240,ko01100,ko02025,ko04113,ko04213,map00230,map00240,map01100,map02025,map04113,map04213	M00053,M00695	R00089,R00434,R02017,R02018,R02019,R02024	RC00295,RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	DUF1451
WH1_k127_5269923_1	926569.ANT_25310	3.292e-85	292.0	COG1996@1|root,COG1996@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4379
WH1_k127_528253_0	525904.Tter_2236	6.577e-87	299.0	COG1975@1|root,COG1975@2|Bacteria,2NPTS@2323|unclassified Bacteria	2|Bacteria	O	XdhC and CoxI family	pucA	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
WH1_k127_5284413_3	195105.CN97_02510	0.0009923	43.0	COG1253@1|root,COG1253@2|Bacteria,1QTUN@1224|Proteobacteria,2TX1H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Membrane protein TerC, possibly involved in tellurium resistance	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,TerC
WH1_k127_5284413_2	926569.ANT_08630	2.101e-48	179.0	COG0295@1|root,COG0295@2|Bacteria,2G7AW@200795|Chloroflexi	200795|Chloroflexi	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
WH1_k127_5284413_1	926569.ANT_31560	2.807e-112	376.0	COG1195@1|root,COG1195@2|Bacteria,2G60N@200795|Chloroflexi	200795|Chloroflexi	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
WH1_k127_5284413_0	926569.ANT_25850	5.48e-113	372.0	COG0265@1|root,COG0265@2|Bacteria,2G6KG@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WH1_k127_5317417_1	102129.Lepto7375DRAFT_6490	7.94e-22	99.0	28I2M@1|root,2Z85A@2|Bacteria,1G2QZ@1117|Cyanobacteria,1H8P5@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF4058)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4058
WH1_k127_5317417_0	926569.ANT_10630	1.201e-29	124.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
WH1_k127_5324693_1	383372.Rcas_1858	6.576e-63	222.0	COG0577@1|root,COG0577@2|Bacteria,2G6IW@200795|Chloroflexi,374ZQ@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH1_k127_5324693_2	671143.DAMO_2920	2.706e-60	217.0	2DRSH@1|root,33CVS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_5324693_0	383372.Rcas_0002	7.543e-119	393.0	COG5621@1|root,COG5621@2|Bacteria,2G6EI@200795|Chloroflexi,374YJ@32061|Chloroflexia	32061|Chloroflexia	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
WH1_k127_5324693_3	398767.Glov_2744	4.696e-16	91.0	COG5617@1|root,COG5617@2|Bacteria,1QXN8@1224|Proteobacteria,431TV@68525|delta/epsilon subdivisions,2WWBH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_5340469_1	926569.ANT_15150	9.49e-57	209.0	COG0631@1|root,COG0631@2|Bacteria,2G8RD@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
WH1_k127_5340469_0	926569.ANT_15160	1.046e-230	732.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
WH1_k127_5340469_2	1128421.JAGA01000003_gene3390	5.592e-14	73.0	COG2353@1|root,COG2353@2|Bacteria,2NPJW@2323|unclassified Bacteria	2|Bacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
WH1_k127_5362494_0	313612.L8106_13405	4.871e-56	200.0	COG1878@1|root,COG1878@2|Bacteria,1G60Q@1117|Cyanobacteria,1HHEV@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
WH1_k127_5362494_1	329726.AM1_0090	6.011e-47	174.0	COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria	1117|Cyanobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
WH1_k127_5372757_3	926569.ANT_13230	2.056e-14	76.0	COG0268@1|root,COG0268@2|Bacteria,2G7AK@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
WH1_k127_5372757_2	443218.AS9A_2944	4.803e-24	113.0	COG3502@1|root,COG3502@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF952)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5,DUF952
WH1_k127_5372757_0	926569.ANT_15050	1.283e-50	194.0	COG0805@1|root,COG0805@2|Bacteria,2G6SP@200795|Chloroflexi	200795|Chloroflexi	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
WH1_k127_5372757_5	926569.ANT_15060	3.03e-07	57.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
WH1_k127_5372757_1	926569.ANT_14610	1.287e-44	172.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi	200795|Chloroflexi	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
WH1_k127_5372757_4	926569.ANT_14620	1.831e-07	55.0	COG1302@1|root,COG1302@2|Bacteria,2G7GB@200795|Chloroflexi	200795|Chloroflexi	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
WH1_k127_5373196_0	1521187.JPIM01000015_gene3769	2.776e-152	493.0	COG0664@1|root,COG2267@1|root,COG0664@2|Bacteria,COG2267@2|Bacteria,2GACD@200795|Chloroflexi,37584@32061|Chloroflexia	32061|Chloroflexia	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,cNMP_binding
WH1_k127_5373196_1	163908.KB235896_gene3556	2.431e-25	123.0	COG0515@1|root,COG3899@1|root,COG4251@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4251@2|Bacteria,1GQ9E@1117|Cyanobacteria,1HIP0@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
WH1_k127_5414456_0	485913.Krac_0170	2.732e-47	184.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WH1_k127_543784_1	1173025.GEI7407_2686	1.179e-16	81.0	COG0463@1|root,COG0463@2|Bacteria,1G03Y@1117|Cyanobacteria,1H789@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
WH1_k127_543784_0	926569.ANT_16640	1.842e-100	336.0	COG0552@1|root,COG0552@2|Bacteria,2G63M@200795|Chloroflexi	200795|Chloroflexi	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
WH1_k127_543784_2	926569.ANT_16650	2.791e-09	69.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WH1_k127_5439442_0	926569.ANT_29920	0.0	1058.0	COG3383@1|root,COG3383@2|Bacteria,2GBH3@200795|Chloroflexi	200795|Chloroflexi	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WH1_k127_5443797_0	926560.KE387023_gene2443	5.222e-98	337.0	COG3408@1|root,COG3408@2|Bacteria,1WM3Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Alkaline and neutral invertase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_100
WH1_k127_5447132_1	926569.ANT_06270	5.507e-114	373.0	COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WH1_k127_5447132_0	926569.ANT_24690	1.67e-160	520.0	COG0064@1|root,COG0064@2|Bacteria,2G62Q@200795|Chloroflexi	200795|Chloroflexi	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
WH1_k127_5447132_3	6238.CBG08811	3.223e-06	51.0	2EW74@1|root,2SY2K@2759|Eukaryota,3AVH6@33154|Opisthokonta,3C40D@33208|Metazoa,3DKPN@33213|Bilateria,40Q8N@6231|Nematoda,1M0JK@119089|Chromadorea,416DZ@6236|Rhabditida	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_5447132_2	926569.ANT_03130	9.261e-47	171.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi	200795|Chloroflexi	E	aminotransferase class I and II	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
WH1_k127_5451754_3	926550.CLDAP_04280	4.713e-33	134.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
WH1_k127_5451754_1	926569.ANT_13990	3.63e-66	235.0	COG0524@1|root,COG0524@2|Bacteria,2G6PQ@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
WH1_k127_5451754_0	926569.ANT_13980	1.853e-101	336.0	COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
WH1_k127_5451754_2	926569.ANT_13970	1.058e-56	206.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
WH1_k127_5453353_1	479434.Sthe_2046	5.323e-10	64.0	29U2R@1|root,30FC1@2|Bacteria,2G9M3@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_5453353_0	478741.JAFS01000002_gene60	1.153e-71	257.0	COG0587@1|root,COG0587@2|Bacteria,46SG0@74201|Verrucomicrobia,37G41@326457|unclassified Verrucomicrobia	2|Bacteria	L	Bacterial DNA polymerase III alpha subunit	dnaE2	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WH1_k127_5469937_2	1278073.MYSTI_00712	1.756e-06	53.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1R4N9@1224|Proteobacteria,43C3R@68525|delta/epsilon subdivisions,2WK5M@28221|Deltaproteobacteria,2Z3AM@29|Myxococcales	2|Bacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_4,PAS_9
WH1_k127_5469937_0	485913.Krac_2351	1.643e-29	124.0	COG0053@1|root,COG0053@2|Bacteria,2G5MK@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WH1_k127_5469937_1	357808.RoseRS_3486	4.797e-13	76.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi,3752Y@32061|Chloroflexia	32061|Chloroflexia	T	Integral membrane sensor signal transduction histidine kinase	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WH1_k127_5474698_0	357808.RoseRS_3820	1.104e-95	336.0	28HGC@1|root,30IRW@2|Bacteria,2GA7N@200795|Chloroflexi,376R6@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial cellulose synthase subunit	-	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB
WH1_k127_5474698_1	1128421.JAGA01000002_gene528	2.99e-59	210.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WH1_k127_5491292_0	926569.ANT_12380	1.434e-141	458.0	COG4992@1|root,COG4992@2|Bacteria,2G5SG@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine	lysJ	-	-	ko:K05830	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00031,M00763	R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,Peptidase_M20
WH1_k127_5492207_0	1121422.AUMW01000005_gene665	4.673e-84	284.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,261BM@186807|Peptococcaceae	186801|Clostridia	E	ABC transporter	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
WH1_k127_5492207_1	1089551.KE386572_gene1700	4.36e-59	214.0	COG0765@1|root,COG0765@2|Bacteria,1QN80@1224|Proteobacteria,2U1R2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0765 ABC-type amino acid transport system permease component	-	-	-	ko:K02029,ko:K10009,ko:K16962	ko02010,map02010	M00234,M00236,M00586	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.10,3.A.1.3.14	-	-	BPD_transp_1
WH1_k127_5493449_1	357808.RoseRS_2505	2.487e-48	179.0	COG4636@1|root,COG4636@2|Bacteria,2G90F@200795|Chloroflexi,377N7@32061|Chloroflexia	32061|Chloroflexia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
WH1_k127_5493449_0	357808.RoseRS_3469	2.274e-81	280.0	COG0331@1|root,COG0331@2|Bacteria,2G61W@200795|Chloroflexi,375EH@32061|Chloroflexia	32061|Chloroflexia	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
WH1_k127_5498339_1	1274374.CBLK010000059_gene467	7.02e-22	99.0	COG1397@1|root,COG1397@2|Bacteria,1TSD8@1239|Firmicutes,4HA33@91061|Bacilli,276T0@186822|Paenibacillaceae	91061|Bacilli	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
WH1_k127_5498339_0	748247.AZKH_4272	1.781e-78	269.0	COG3568@1|root,COG3568@2|Bacteria,1PPNP@1224|Proteobacteria	1224|Proteobacteria	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
WH1_k127_5508008_1	1122223.KB890700_gene2058	3.386e-28	116.0	COG0477@1|root,COG2814@2|Bacteria,1WJGK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH1_k127_5508008_0	926569.ANT_04160	2.499e-28	118.0	COG1950@1|root,COG1950@2|Bacteria,2G7E6@200795|Chloroflexi	200795|Chloroflexi	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
WH1_k127_5510821_1	1245475.ANAE01000125_gene440	8.58e-06	54.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4EFKZ@85012|Streptosporangiales	201174|Actinobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
WH1_k127_5510821_0	926550.CLDAP_29950	4.764e-175	566.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi	200795|Chloroflexi	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
WH1_k127_5520570_0	395494.Galf_1567	4.777e-26	115.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	PFAM Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	SPOR,Sel1
WH1_k127_5520570_1	452637.Oter_1010	4.824e-18	86.0	COG0810@1|root,COG0810@2|Bacteria,46WU9@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
WH1_k127_5525229_0	1961.JOAK01000001_gene3224	1.563e-06	53.0	COG0160@1|root,COG3629@1|root,COG3903@1|root,COG0160@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2GP5Z@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase class-III	-	-	2.6.1.55	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
WH1_k127_5531821_1	926569.ANT_14010	2.035e-81	278.0	COG2003@1|root,COG2003@2|Bacteria,2G6BK@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the UPF0758 family	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
WH1_k127_5531821_2	926569.ANT_14000	3.236e-48	177.0	COG1933@1|root,COG1933@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease I activity	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,PLDc_N,zf-ribbon_3,zinc_ribbon_2
WH1_k127_5531821_0	357808.RoseRS_2162	1.572e-91	318.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,3750C@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,SpoIIE
WH1_k127_554060_1	525904.Tter_2549	3.79e-39	162.0	COG3850@1|root,COG3850@2|Bacteria,2NS42@2323|unclassified Bacteria	2|Bacteria	T	histidine kinase dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K03406,ko:K07673,ko:K07675	ko02020,ko02030,map02020,map02030	M00471,M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,LapD_MoxY_N
WH1_k127_554060_0	479434.Sthe_0243	2.027e-59	227.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH1_k127_554060_2	760117.JN27_15495	0.0001978	49.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,2VQAN@28216|Betaproteobacteria,472ZU@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH1_k127_5541933_0	309801.trd_1313	3.513e-57	220.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WH1_k127_5541933_1	710696.Intca_3060	2.063e-32	139.0	COG0350@1|root,COG1357@1|root,COG0350@2|Bacteria,COG1357@2|Bacteria,2GKA9@201174|Actinobacteria,4FGDJ@85021|Intrasporangiaceae	201174|Actinobacteria	L	Methyltransferase	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
WH1_k127_5541933_2	479434.Sthe_2174	5.412e-29	122.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH1_k127_5547603_1	670292.JH26_24920	9.184e-24	119.0	COG0745@1|root,COG0745@2|Bacteria,1RD6H@1224|Proteobacteria,2UCJ0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WH1_k127_5547603_0	477974.Daud_1728	1.132e-110	392.0	COG2202@1|root,COG2203@1|root,COG3437@1|root,COG3605@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3605@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,261WQ@186807|Peptococcaceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,HD,HD_5
WH1_k127_5559894_0	926560.KE387023_gene2446	9.482e-279	869.0	COG1472@1|root,COG1472@2|Bacteria,1WKZQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Fibronectin type III-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
WH1_k127_5559894_1	1131730.BAVI_16837	6.128e-122	399.0	COG1940@1|root,COG1940@2|Bacteria,1TRGJ@1239|Firmicutes,4IMXV@91061|Bacilli,1ZM5R@1386|Bacillus	91061|Bacilli	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
WH1_k127_5559894_2	1124780.ANNU01000062_gene572	5.516e-71	248.0	COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,47KZ6@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
WH1_k127_5559894_3	1304880.JAGB01000003_gene1255	1.078e-43	161.0	COG0407@1|root,COG0407@2|Bacteria,1V3M9@1239|Firmicutes,25AY7@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
WH1_k127_5561531_0	926569.ANT_28210	1.623e-143	469.0	COG0366@1|root,COG0366@2|Bacteria,2G5NW@200795|Chloroflexi	200795|Chloroflexi	G	SMART alpha amylase catalytic sub domain	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459,Malt_amylase_C
WH1_k127_5561531_2	756067.MicvaDRAFT_5408	2.496e-106	354.0	COG1716@1|root,COG1716@2|Bacteria,1G09Z@1117|Cyanobacteria,1H7K7@1150|Oscillatoriales	1117|Cyanobacteria	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_5561531_1	472759.Nhal_3067	2.767e-108	363.0	COG0707@1|root,COG0707@2|Bacteria,1QW3F@1224|Proteobacteria,1T2RC@1236|Gammaproteobacteria,1X2NR@135613|Chromatiales	135613|Chromatiales	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_5569845_1	1122182.KB903826_gene953	3.117e-10	68.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria,4D8TF@85008|Micromonosporales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH1_k127_5569845_0	1283299.AUKG01000003_gene608	1.293e-48	184.0	COG2114@1|root,COG2770@1|root,COG2114@2|Bacteria,COG2770@2|Bacteria,2IANW@201174|Actinobacteria,4CP68@84995|Rubrobacteria	84995|Rubrobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HAMP
WH1_k127_5577003_0	266117.Rxyl_1300	3.44e-168	536.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4CPK9@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
WH1_k127_5578299_1	926550.CLDAP_35790	1.313e-08	57.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi	200795|Chloroflexi	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WH1_k127_5578299_0	926550.CLDAP_09690	6.548e-68	252.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
WH1_k127_5580398_0	926550.CLDAP_06100	6.098e-106	351.0	COG0463@1|root,COG0463@2|Bacteria,2GA7J@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH1_k127_5605790_2	293826.Amet_0335	1.27e-09	64.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,36EMG@31979|Clostridiaceae	186801|Clostridia	M	Penicillin-binding Protein	pbpA2	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
WH1_k127_5605790_1	926550.CLDAP_22390	1.23e-131	433.0	COG0162@1|root,COG0162@2|Bacteria,2G64J@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
WH1_k127_5605790_0	926569.ANT_16840	1.68e-271	847.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WH1_k127_5612273_1	1121430.JMLG01000009_gene482	6.466e-07	55.0	COG1520@1|root,COG5492@1|root,COG1520@2|Bacteria,COG5492@2|Bacteria,1UJJG@1239|Firmicutes,25F4J@186801|Clostridia,267DY@186807|Peptococcaceae	186801|Clostridia	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
WH1_k127_5612273_0	443143.GM18_4316	2.811e-74	265.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2WJPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Big_2,CUB,He_PIG,Peptidase_S8
WH1_k127_5612386_1	1121430.JMLG01000009_gene482	3.783e-08	59.0	COG1520@1|root,COG5492@1|root,COG1520@2|Bacteria,COG5492@2|Bacteria,1UJJG@1239|Firmicutes,25F4J@186801|Clostridia,267DY@186807|Peptococcaceae	186801|Clostridia	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
WH1_k127_5612386_0	304371.MCP_0966	6.194e-63	226.0	COG0863@1|root,arCOG00115@2157|Archaea,2Y8E2@28890|Euryarchaeota	28890|Euryarchaeota	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
WH1_k127_5615041_0	926569.ANT_10330	8.153e-63	226.0	COG0101@1|root,COG0101@2|Bacteria,2G6PE@200795|Chloroflexi	200795|Chloroflexi	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
WH1_k127_5615041_1	1410631.JHWZ01000014_gene821	2.85e-56	200.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,27M8F@186928|unclassified Lachnospiraceae	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
WH1_k127_5615041_2	926569.ANT_10350	3.401e-16	80.0	COG0103@1|root,COG0103@2|Bacteria,2G6UZ@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
WH1_k127_5631871_0	335541.Swol_1723	1.424e-87	296.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WH1_k127_5631871_1	357808.RoseRS_2418	1.206e-42	173.0	COG1277@1|root,COG1277@2|Bacteria,2GBME@200795|Chloroflexi,3782B@32061|Chloroflexia	32061|Chloroflexia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_5631871_2	765420.OSCT_1965	6.221e-21	106.0	COG5022@1|root,COG5022@2|Bacteria,2GBHX@200795|Chloroflexi,37800@32061|Chloroflexia	32061|Chloroflexia	Z	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_5634494_0	1128421.JAGA01000003_gene3188	5.46e-89	303.0	COG1283@1|root,COG1283@2|Bacteria	2|Bacteria	P	sodium-dependent phosphate transmembrane transporter activity	-	-	-	ko:K03324,ko:K03466	-	-	-	-	ko00000,ko02000,ko03036	2.A.58.2,3.A.12	-	-	Na_Pi_cotrans,PHO4,PhoU
WH1_k127_5651483_2	945713.IALB_2676	1.754e-84	284.0	COG4947@1|root,COG4947@2|Bacteria	2|Bacteria	P	esterase	XK27_05675	-	-	-	-	-	-	-	-	-	-	-	Esterase
WH1_k127_5651483_0	1210884.HG799465_gene12056	8.198e-139	449.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_5651483_3	7245.FBpp0260894	6.707e-10	70.0	2D82N@1|root,2T8G1@2759|Eukaryota,3930P@33154|Opisthokonta,3C8AX@33208|Metazoa,3DPBM@33213|Bilateria,425JT@6656|Arthropoda,3SV54@50557|Insecta,4587U@7147|Diptera,45Z7T@7214|Drosophilidae	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_5651483_1	1210884.HG799465_gene12055	4.739e-127	417.0	COG2308@1|root,COG2308@2|Bacteria	2|Bacteria	S	glutamate-cysteine ligase activity	-	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	CP_ATPgrasp_2,GSP_synth
WH1_k127_5658239_0	926550.CLDAP_19690	3.072e-271	846.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi	200795|Chloroflexi	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WH1_k127_5658239_1	926550.CLDAP_12950	2.578e-27	115.0	COG3695@1|root,COG3695@2|Bacteria,2G7CY@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
WH1_k127_5663160_0	909663.KI867150_gene72	1.143e-56	200.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2MRD6@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	helicase superfamily c-terminal domain	rhlE-2	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
WH1_k127_5663160_1	1298858.AUEL01000019_gene3260	2.626e-12	75.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
WH1_k127_5671247_1	357808.RoseRS_0905	4.5e-62	233.0	COG0419@1|root,COG0419@2|Bacteria,2G682@200795|Chloroflexi,375BN@32061|Chloroflexia	32061|Chloroflexia	L	PFAM SMC domain protein	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SbcCD_C
WH1_k127_5671247_2	1254432.SCE1572_40715	3.814e-54	209.0	COG4325@1|root,COG4325@2|Bacteria,1QKIM@1224|Proteobacteria,43411@68525|delta/epsilon subdivisions,2X4JG@28221|Deltaproteobacteria,2YZ4U@29|Myxococcales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
WH1_k127_5671247_3	525904.Tter_2599	5.244e-39	160.0	COG0451@1|root,COG0451@2|Bacteria,2NPZU@2323|unclassified Bacteria	2|Bacteria	M	Male sterility protein	-	-	1.1.1.219,5.1.3.26	ko:K00091,ko:K19997	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
WH1_k127_5671247_5	85643.Tmz1t_0744	0.0002709	51.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Lectin_legB,NB-ARC,WD40
WH1_k127_5671247_0	326427.Cagg_1927	8.891e-70	245.0	COG1836@1|root,COG1836@2|Bacteria,2G6N3@200795|Chloroflexi,375N7@32061|Chloroflexia	32061|Chloroflexia	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
WH1_k127_5671247_4	292459.STH1623	3.529e-05	49.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,1TSPA@1239|Firmicutes	1239|Firmicutes	L	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine	yprA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
WH1_k127_5703450_1	526227.Mesil_0835	2.053e-49	184.0	COG0366@1|root,COG0366@2|Bacteria,1WI07@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM alpha amylase, catalytic	-	-	3.2.1.1,3.2.1.20	ko:K01176,ko:K01187	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00028,R00801,R00802,R02108,R02112,R06087,R06088,R11262	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459
WH1_k127_5703450_0	1499967.BAYZ01000171_gene5534	1.135e-125	421.0	COG0589@1|root,COG1475@1|root,COG0589@2|Bacteria,COG1475@2|Bacteria,2NS1X@2323|unclassified Bacteria	2|Bacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,ParBc,Usp
WH1_k127_5708140_0	1268622.AVS7_02036	1.125e-10	76.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1MVB8@1224|Proteobacteria,2VHKT@28216|Betaproteobacteria,4A9QG@80864|Comamonadaceae	28216|Betaproteobacteria	D	Cellulose synthase operon protein C C-terminus (BCSC_C)	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	BCSC_C,TPR_16,TPR_19,TPR_8
WH1_k127_5708140_1	861299.J421_3057	0.0001549	52.0	COG0457@1|root,COG0457@2|Bacteria,1ZSS6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
WH1_k127_5717528_0	33876.JNXY01000040_gene6765	4.927e-114	377.0	COG0715@1|root,COG0715@2|Bacteria,2HU64@201174|Actinobacteria,4DBYJ@85008|Micromonosporales	201174|Actinobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
WH1_k127_5717528_1	1463855.JOHV01000020_gene3022	1.554e-58	216.0	COG0600@1|root,COG0600@2|Bacteria,2IFIB@201174|Actinobacteria	201174|Actinobacteria	P	inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
WH1_k127_5717528_2	1121382.JQKG01000004_gene3928	1.225e-21	95.0	COG1116@1|root,COG1116@2|Bacteria,1WM71@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
WH1_k127_5720358_1	309807.SRU_0860	5.22e-25	114.0	COG0631@1|root,COG0631@2|Bacteria,4P5NB@976|Bacteroidetes,1FJHA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Protein phosphatase 2C	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2,SpoIIE
WH1_k127_5720358_0	497964.CfE428DRAFT_0448	6.105e-86	293.0	COG2304@1|root,COG2304@2|Bacteria,46VUT@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_5720358_2	1499967.BAYZ01000076_gene800	2.299e-19	94.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K02012,ko:K07114	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	1.A.13.2.2,1.A.13.2.3,3.A.1.10	-	-	SBP_bac_11,VWA,VWA_2,VWA_3
WH1_k127_5722276_0	871963.Desdi_1115	3.597e-174	568.0	COG1138@1|root,COG1138@2|Bacteria,1UH6S@1239|Firmicutes,24BV3@186801|Clostridia,26427@186807|Peptococcaceae	186801|Clostridia	O	PFAM Cytochrome C assembly protein	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
WH1_k127_5722276_1	926569.ANT_19460	3.321e-34	139.0	COG3088@1|root,COG3088@2|Bacteria,2G72W@200795|Chloroflexi	200795|Chloroflexi	O	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
WH1_k127_5724098_0	383372.Rcas_2888	2.407e-25	110.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi,374YS@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WH1_k127_5724098_1	203124.Tery_2811	3.063e-19	101.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria,1H84Z@1150|Oscillatoriales	1117|Cyanobacteria	U	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
WH1_k127_5730631_1	398767.Glov_2401	6.361e-55	199.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria,43V0Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
WH1_k127_5730631_0	1379698.RBG1_1C00001G0907	3.381e-143	462.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	bamA	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788	3.7.1.21	ko:K07539,ko:K18570	ko00332,ko00362,ko01100,ko01120,ko01130,ko01220,map00332,map00362,map01100,map01120,map01130,map01220	M00541	R05593,R05594,R10696,R10750	RC01430,RC01431,RC03237,RC03270	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WH1_k127_5730631_2	379066.GAU_3677	2.979e-45	173.0	COG4832@1|root,COG4832@2|Bacteria	2|Bacteria	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
WH1_k127_5737867_0	1382306.JNIM01000001_gene1603	1.549e-72	259.0	COG1159@1|root,COG3597@1|root,COG1159@2|Bacteria,COG3597@2|Bacteria,2G9CM@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	-	-	-	-	-	-	-	-	-	-	-	-	DUF697,MMR_HSR1
WH1_k127_5737867_1	316274.Haur_4656	8.457e-41	173.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2GBIX@200795|Chloroflexi,3759D@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4
WH1_k127_5740520_2	926569.ANT_02240	2.71e-25	111.0	COG0858@1|root,COG0858@2|Bacteria,2G73E@200795|Chloroflexi	200795|Chloroflexi	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
WH1_k127_5740520_0	926569.ANT_02250	4.645e-232	733.0	COG0532@1|root,COG0532@2|Bacteria,2G5UR@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
WH1_k127_5740520_3	1128421.JAGA01000004_gene2588	6.552e-21	96.0	COG2740@1|root,COG2740@2|Bacteria,2NRZC@2323|unclassified Bacteria	2|Bacteria	K	Protein of unknown function (DUF448)	ylxR	-	-	ko:K02600,ko:K07742	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	DUF448
WH1_k127_5740520_1	926569.ANT_02270	3.853e-55	206.0	COG0195@1|root,COG0195@2|Bacteria,2G5M5@200795|Chloroflexi	200795|Chloroflexi	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
WH1_k127_5754330_1	324602.Caur_0168	1.478e-93	310.0	COG0065@1|root,COG0065@2|Bacteria,2G68G@200795|Chloroflexi,3753P@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
WH1_k127_5754330_2	926569.ANT_03320	5.003e-74	254.0	COG0066@1|root,COG0066@2|Bacteria,2G6JE@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
WH1_k127_5754330_0	1242864.D187_003310	1.157e-137	445.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2YV73@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WH1_k127_5755868_1	926569.ANT_04000	4.412e-69	243.0	COG3868@1|root,COG3868@2|Bacteria	2|Bacteria	S	Glycoside-hydrolase family GH114	-	-	-	ko:K21006	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	Glyco_hydro_114
WH1_k127_5755868_0	429009.Adeg_0970	2.74e-81	278.0	COG2378@1|root,COG2378@2|Bacteria,1TT23@1239|Firmicutes,248A8@186801|Clostridia,42FKV@68295|Thermoanaerobacterales	186801|Clostridia	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
WH1_k127_576181_1	1123368.AUIS01000006_gene571	2.182e-59	210.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,1T2K7@1236|Gammaproteobacteria,2NDJ6@225057|Acidithiobacillales	1236|Gammaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Phosphonate-bd
WH1_k127_576181_2	251229.Chro_2414	5.26e-32	143.0	COG0745@1|root,COG2202@1|root,COG2204@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,3VHZD@52604|Pleurocapsales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
WH1_k127_576181_3	7245.FBpp0260894	9.202e-05	45.0	2D82N@1|root,2T8G1@2759|Eukaryota,3930P@33154|Opisthokonta,3C8AX@33208|Metazoa,3DPBM@33213|Bilateria,425JT@6656|Arthropoda,3SV54@50557|Insecta,4587U@7147|Diptera,45Z7T@7214|Drosophilidae	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_576181_0	671143.DAMO_3139	8.415e-124	426.0	COG0784@1|root,COG2199@1|root,COG2203@1|root,COG3850@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3850@2|Bacteria,2NQK2@2323|unclassified Bacteria	2|Bacteria	T	diguanylate cyclase	-	-	2.7.13.3	ko:K07678,ko:K07679	ko02020,ko02025,ko02026,ko05111,ko05133,map02020,map02025,map02026,map05111,map05133	M00475,M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE3,GAF,GAF_2,GGDEF,HAMP,PAS_3,PAS_9,Response_reg
WH1_k127_5766133_2	765420.OSCT_2127	2.926e-29	121.0	2CVPW@1|root,32SXZ@2|Bacteria,2G7DV@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_5766133_1	765420.OSCT_2126	7.857e-34	138.0	2A540@1|root,30TSN@2|Bacteria,2G9TT@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_5766133_0	525904.Tter_1019	1.165e-74	260.0	COG4962@1|root,COG4962@2|Bacteria	2|Bacteria	U	Type ii secretion system protein e	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
WH1_k127_5771558_1	479434.Sthe_2752	1.008e-18	91.0	COG0489@1|root,COG3206@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,COG3944@2|Bacteria,2G5WM@200795|Chloroflexi,27Y7Y@189775|Thermomicrobia	200795|Chloroflexi	DM	Capsular exopolysaccharide family	-	-	2.7.10.2	ko:K08253	-	-	-	-	ko00000,ko01000	-	-	-	CbiA,GNVR,Wzz
WH1_k127_5771558_0	632518.Calow_1970	1.947e-58	213.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,42EZ1@68295|Thermoanaerobacterales	186801|Clostridia	D	Capsular exopolysaccharide family	ywqD	-	-	-	-	-	-	-	-	-	-	-	AAA_31,ParA,Wzz
WH1_k127_5772696_0	404589.Anae109_2250	1.242e-170	551.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42PVA@68525|delta/epsilon subdivisions,2WJ10@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB-1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
WH1_k127_5783814_2	635013.TherJR_0982	2.397e-05	49.0	COG0407@1|root,COG0407@2|Bacteria,1UYXW@1239|Firmicutes,25DH8@186801|Clostridia,264CR@186807|Peptococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	2.1.1.246	ko:K14080	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00356	R09098,R10000	RC00035,RC01144,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,URO-D
WH1_k127_5783814_1	317619.ANKN01000044_gene1970	4.456e-26	112.0	COG2703@1|root,COG2703@2|Bacteria,1G85F@1117|Cyanobacteria	1117|Cyanobacteria	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
WH1_k127_5783814_0	357808.RoseRS_0056	3.046e-125	412.0	COG1061@1|root,COG1112@1|root,COG1061@2|Bacteria,COG1112@2|Bacteria,2GB6S@200795|Chloroflexi,377GI@32061|Chloroflexia	32061|Chloroflexia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
WH1_k127_5785989_0	479434.Sthe_0657	2.174e-40	166.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CHAT,PD40
WH1_k127_5785989_1	1294142.CINTURNW_2335	3.721e-07	61.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,36EWT@31979|Clostridiaceae	186801|Clostridia	O	SPFH domain Band 7 family	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
WH1_k127_5789119_1	1499967.BAYZ01000076_gene800	5.684e-125	420.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K02012,ko:K07114	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	1.A.13.2.2,1.A.13.2.3,3.A.1.10	-	-	SBP_bac_11,VWA,VWA_2,VWA_3
WH1_k127_5789119_2	67315.JOBD01000050_gene4940	5.981e-31	132.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria	201174|Actinobacteria	KLT	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase
WH1_k127_5789119_0	1403819.BATR01000040_gene1195	6.089e-222	697.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3,AAA_5
WH1_k127_5793310_1	309807.SRU_2743	2.559e-76	263.0	COG0366@1|root,COG0366@2|Bacteria,4PIQU@976|Bacteroidetes,1FJWV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Alpha-amylase domain	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
WH1_k127_5793310_0	1128421.JAGA01000001_gene2073	2.107e-92	328.0	COG0366@1|root,COG0366@2|Bacteria,2NR0V@2323|unclassified Bacteria	2|Bacteria	G	Alpha-amylase domain	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
WH1_k127_5795733_4	926550.CLDAP_03580	1.54e-68	250.0	COG0477@1|root,COG2814@2|Bacteria,2GA7I@200795|Chloroflexi	200795|Chloroflexi	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH1_k127_5795733_5	1128421.JAGA01000002_gene101	3.002e-39	156.0	COG0584@1|root,COG0584@2|Bacteria,2NPNS@2323|unclassified Bacteria	2|Bacteria	C	PFAM Glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
WH1_k127_5795733_0	926569.ANT_28910	4.251e-181	576.0	COG0104@1|root,COG0104@2|Bacteria,2G602@200795|Chloroflexi	200795|Chloroflexi	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
WH1_k127_5795733_1	926550.CLDAP_04540	4.831e-132	448.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
WH1_k127_5795733_2	479434.Sthe_0904	6.902e-90	309.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH1_k127_5795733_3	326427.Cagg_2445	2.187e-78	269.0	COG0438@1|root,COG0438@2|Bacteria,2G5QJ@200795|Chloroflexi,3756M@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH1_k127_5804225_0	1121405.dsmv_1613	1.208e-138	451.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria	1224|Proteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
WH1_k127_580580_0	635013.TherJR_1461	1.741e-96	329.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,260BK@186807|Peptococcaceae	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
WH1_k127_580580_1	305700.B447_20945	1.246e-67	240.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria,2KV2M@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
WH1_k127_5816055_1	926550.CLDAP_23270	2.834e-68	237.0	COG0463@1|root,COG0463@2|Bacteria,2GBP0@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WH1_k127_5816055_0	479434.Sthe_1590	4.484e-135	437.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi,27XT7@189775|Thermomicrobia	189775|Thermomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WH1_k127_5816055_2	1521187.JPIM01000009_gene2196	1.245e-20	97.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi,374YS@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WH1_k127_5840750_0	9361.ENSDNOP00000026180	3.533e-128	419.0	COG0458@1|root,KOG0370@2759|Eukaryota,38CAC@33154|Opisthokonta,3B9FF@33208|Metazoa,3CS9A@33213|Bilateria,4804V@7711|Chordata,490QX@7742|Vertebrata,3J7SX@40674|Mammalia	33208|Metazoa	F	aspartate binding	CAD	GO:0000050,GO:0000052,GO:0000166,GO:0001882,GO:0001884,GO:0002119,GO:0002134,GO:0002164,GO:0003674,GO:0003824,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004672,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006228,GO:0006464,GO:0006468,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009605,GO:0009653,GO:0009719,GO:0009725,GO:0009791,GO:0009887,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0016053,GO:0016301,GO:0016310,GO:0016363,GO:0016597,GO:0016740,GO:0016741,GO:0016743,GO:0016772,GO:0016773,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0017144,GO:0018107,GO:0018130,GO:0018193,GO:0018210,GO:0019103,GO:0019240,GO:0019438,GO:0019538,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0019899,GO:0022612,GO:0030424,GO:0030554,GO:0031406,GO:0031667,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0032868,GO:0032991,GO:0033267,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0035295,GO:0035639,GO:0036094,GO:0036211,GO:0036477,GO:0042221,GO:0042455,GO:0042594,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043195,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043434,GO:0043436,GO:0043603,GO:0043604,GO:0043679,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0045202,GO:0046051,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046394,GO:0046483,GO:0046777,GO:0046872,GO:0046914,GO:0048513,GO:0048565,GO:0048731,GO:0048732,GO:0048856,GO:0050896,GO:0055086,GO:0055123,GO:0060465,GO:0070013,GO:0070335,GO:0070406,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:0097458,GO:0098793,GO:0120025,GO:0120038,GO:0140096,GO:0150034,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901652,GO:1901657,GO:1901659,GO:1901698,GO:1901700,GO:1905905	2.1.3.2,3.5.2.3,6.3.5.5	ko:K11540	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R01397,R01993,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00632,RC02750,RC02798,RC02850,RC03314	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Amidohydro_1,CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,GATase,MGS,OTCace,OTCace_N
WH1_k127_5846264_3	1502851.FG93_02677	0.0004857	43.0	COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,2TVMU@28211|Alphaproteobacteria,3JRR4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Coenzyme A transferase	catI	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WH1_k127_5846264_1	324602.Caur_1277	2.184e-23	104.0	2E65M@1|root,330UB@2|Bacteria,2G8DC@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WH1_k127_5846264_2	1123389.ATXJ01000032_gene1671	2.151e-16	82.0	COG4118@1|root,COG4118@2|Bacteria,1WKUE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
WH1_k127_5846264_0	671143.DAMO_2720	5.929e-33	133.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
WH1_k127_584969_0	926569.ANT_11850	2.366e-37	143.0	COG0784@1|root,COG0784@2|Bacteria,2GBNB@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WH1_k127_584969_1	926569.ANT_11840	0.0002896	45.0	COG0784@1|root,COG0784@2|Bacteria,2G9B3@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WH1_k127_5856353_1	926569.ANT_02780	3.133e-48	177.0	COG0424@1|root,COG0424@2|Bacteria,2G6U2@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Maf family protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
WH1_k127_5856353_0	926569.ANT_02790	6.536e-155	523.0	COG0768@1|root,COG0768@2|Bacteria,2G7WI@200795|Chloroflexi	200795|Chloroflexi	M	NTF2-like N-terminal transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
WH1_k127_5860300_0	522306.CAP2UW1_3003	3.396e-87	295.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,2VJYR@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF5110,Glyco_hydro_31
WH1_k127_5868858_0	485913.Krac_8496	1.93e-55	205.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
WH1_k127_5878785_2	1449355.JQNR01000005_gene5969	8.057e-09	58.0	COG2971@1|root,COG2971@2|Bacteria	2|Bacteria	G	N-acetylglucosamine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
WH1_k127_5878785_1	525904.Tter_2131	1.59e-74	258.0	COG0363@1|root,COG0363@2|Bacteria,2NPPJ@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.1.1.31,3.5.99.6	ko:K01057,ko:K02564	ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
WH1_k127_5878785_0	525904.Tter_2132	1.434e-101	335.0	COG1486@1|root,COG1486@2|Bacteria,2NPAR@2323|unclassified Bacteria	2|Bacteria	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22,3.2.1.86	ko:K01222,ko:K07406	ko00010,ko00052,ko00500,ko00561,ko00600,ko00603,map00010,map00052,map00500,map00561,map00600,map00603	-	R00839,R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05133,R05134,R05549,R05961,R06091	RC00049,RC00059,RC00171,RC00451,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
WH1_k127_589371_1	383372.Rcas_1058	4.433e-14	77.0	COG0747@1|root,COG0747@2|Bacteria,2G5KD@200795|Chloroflexi,3768F@32061|Chloroflexia	32061|Chloroflexia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
WH1_k127_589371_0	926550.CLDAP_00560	2.005e-38	154.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
WH1_k127_5908308_0	215803.DB30_2248	2.147e-15	80.0	COG4576@1|root,COG4576@2|Bacteria,1Q8QH@1224|Proteobacteria,4354D@68525|delta/epsilon subdivisions,2WZFG@28221|Deltaproteobacteria,2Z20V@29|Myxococcales	28221|Deltaproteobacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
WH1_k127_5915087_0	760568.Desku_0307	1.495e-120	410.0	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,260RA@186807|Peptococcaceae	186801|Clostridia	KL	DNA RNA helicase, superfamily II, SNF2 family	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	DUF3670,Helicase_C,SNF2_N,SWIM
WH1_k127_5947672_1	926569.ANT_10880	1.66e-14	76.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,DUF1906,PG_binding_1,Peptidase_M15_4
WH1_k127_5947672_0	234267.Acid_0350	2.179e-119	396.0	COG2723@1|root,COG2723@2|Bacteria,3Y5XS@57723|Acidobacteria	57723|Acidobacteria	G	6-phospho-beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_5948522_1	1123060.JONP01000003_gene238	9.45e-49	183.0	COG1014@1|root,COG1014@2|Bacteria,1MV7Q@1224|Proteobacteria,2TTHE@28211|Alphaproteobacteria,2JQ2E@204441|Rhodospirillales	204441|Rhodospirillales	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	POR
WH1_k127_5948522_0	1123504.JQKD01000007_gene3331	1.404e-99	333.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VK1K@28216|Betaproteobacteria,4AASY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Indolepyruvate ferredoxin oxidoreductase	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	TPP_enzyme_C
WH1_k127_595087_1	443143.GM18_4316	1.696e-68	259.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2WJPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Big_2,CUB,He_PIG,Peptidase_S8
WH1_k127_595087_0	883.DvMF_2252	2.461e-183	585.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42Q0K@68525|delta/epsilon subdivisions,2WJUW@28221|Deltaproteobacteria,2M8AC@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Belongs to the DEAD box helicase family	dedA	-	3.6.4.13	ko:K03732,ko:K05592	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
WH1_k127_595087_2	313612.L8106_14590	5.456e-30	133.0	COG2730@1|root,COG2931@1|root,COG3386@1|root,COG2730@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,1G3DW@1117|Cyanobacteria,1HAZM@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,DUF4347,HemolysinCabind
WH1_k127_5965230_1	926569.ANT_06880	3.209e-94	334.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	devS	GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K07682	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HisKA_3
WH1_k127_5965230_3	926569.ANT_03110	6.52e-46	181.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WH1_k127_5965230_0	926569.ANT_03120	9.415e-102	350.0	COG4448@1|root,COG4448@2|Bacteria	2|Bacteria	E	L-asparaginase II	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase_II
WH1_k127_5965230_2	926569.ANT_02480	1.113e-65	230.0	COG0290@1|root,COG0290@2|Bacteria,2G6N2@200795|Chloroflexi	200795|Chloroflexi	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
WH1_k127_5965230_5	926569.ANT_00600	2.013e-21	96.0	COG0291@1|root,COG0291@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
WH1_k127_5965230_4	926569.ANT_00590	1.579e-40	153.0	COG0292@1|root,COG0292@2|Bacteria,2G6V4@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
WH1_k127_5965230_6	316274.Haur_4637	0.0007801	47.0	COG0566@1|root,COG0566@2|Bacteria,2G6MC@200795|Chloroflexi,376U0@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
WH1_k127_5969266_1	926569.ANT_28790	1.101e-57	205.0	COG1545@1|root,COG1545@2|Bacteria,2G73Z@200795|Chloroflexi	200795|Chloroflexi	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
WH1_k127_5969266_0	926569.ANT_28810	1.305e-136	439.0	COG3425@1|root,COG3425@2|Bacteria,2G606@200795|Chloroflexi	200795|Chloroflexi	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C
WH1_k127_5974463_1	926550.CLDAP_19380	1.876e-62	233.0	COG0845@1|root,COG0845@2|Bacteria,2G6RK@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WH1_k127_5974463_0	926569.ANT_13820	2.259e-72	250.0	COG2344@1|root,COG2344@2|Bacteria,2G6EJ@200795|Chloroflexi	200795|Chloroflexi	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
WH1_k127_5974463_2	926550.CLDAP_05030	1.433e-39	149.0	COG1077@1|root,COG1077@2|Bacteria,2G5KV@200795|Chloroflexi	200795|Chloroflexi	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
WH1_k127_5993921_2	926550.CLDAP_11170	4.196e-80	272.0	COG0154@1|root,COG0154@2|Bacteria,2G5T0@200795|Chloroflexi	200795|Chloroflexi	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WH1_k127_5993921_1	926569.ANT_03150	1.981e-107	357.0	COG1208@1|root,COG1208@2|Bacteria,2G5KH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WH1_k127_5993921_0	1128421.JAGA01000002_gene1310	1.013e-110	363.0	COG0436@1|root,COG0436@2|Bacteria,2NP1C@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase	yugH	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WH1_k127_6004727_0	926550.CLDAP_28180	3.817e-56	208.0	COG0642@1|root,COG0784@1|root,COG2204@1|root,COG0784@2|Bacteria,COG2204@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WH1_k127_6006198_1	1121472.AQWN01000003_gene1516	1.825e-42	157.0	COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,24HAR@186801|Clostridia,26296@186807|Peptococcaceae	186801|Clostridia	I	methylmalonyl-CoA mutase C-terminal	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
WH1_k127_6006198_0	1380394.JADL01000003_gene4842	6.779e-123	402.0	COG0183@1|root,COG0183@2|Bacteria,1MXYM@1224|Proteobacteria,2TUBT@28211|Alphaproteobacteria,2JV5N@204441|Rhodospirillales	204441|Rhodospirillales	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
WH1_k127_6009809_0	211114.JOEF01000001_gene7240	1.657e-67	234.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4E068@85010|Pseudonocardiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH1_k127_6009809_1	543632.JOJL01000004_gene4132	2.542e-37	145.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4DB80@85008|Micromonosporales	201174|Actinobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	degS	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
WH1_k127_601254_2	1122138.AQUZ01000040_gene6209	7.057e-11	68.0	COG0346@1|root,COG0346@2|Bacteria,2IS4J@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WH1_k127_601254_0	926550.CLDAP_05540	1.112e-53	200.0	COG0726@1|root,COG0726@2|Bacteria,2G6VJ@200795|Chloroflexi	200795|Chloroflexi	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
WH1_k127_601254_1	926550.CLDAP_01930	2.971e-49	192.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
WH1_k127_6013471_0	357808.RoseRS_2190	4.352e-54	199.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
WH1_k127_6017208_1	1382356.JQMP01000001_gene1050	1.373e-50	188.0	COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi,27XIQ@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WH1_k127_6017208_0	2074.JNYD01000030_gene6611	4.58e-52	194.0	COG1173@1|root,COG1173@2|Bacteria,2GN0C@201174|Actinobacteria,4E13D@85010|Pseudonocardiales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WH1_k127_6017208_2	765912.Thimo_2070	2.679e-48	184.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1WW7F@135613|Chromatiales	135613|Chromatiales	EP	PFAM Binding-protein-dependent transport	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WH1_k127_6019603_0	1140.Synpcc7942_0357	0.0003443	53.0	COG3307@1|root,COG3307@2|Bacteria,1G1ZH@1117|Cyanobacteria,1GZSF@1129|Synechococcus	1117|Cyanobacteria	M	COG3307 Lipid A core - O-antigen ligase and related enzymes	ictB	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
WH1_k127_6023375_0	765420.OSCT_2813	9.025e-53	194.0	COG1719@1|root,COG1719@2|Bacteria	2|Bacteria	KT	4-vinyl reductase, 4VR	-	-	-	ko:K07013,ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	V4R
WH1_k127_6023375_1	926550.CLDAP_00660	3.443e-24	109.0	COG1319@1|root,COG1319@2|Bacteria,2G9PS@200795|Chloroflexi	200795|Chloroflexi	C	FAD binding domain in molybdopterin dehydrogenase	-	-	1.2.5.3	ko:K03519,ko:K12529	ko00450,map00450	-	R07229,R11168	RC02420,RC02800	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
WH1_k127_6037929_0	1444309.JAQG01000011_gene2244	4.679e-39	153.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,26T63@186822|Paenibacillaceae	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
WH1_k127_6037929_1	443143.GM18_3607	4.774e-13	75.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,42ZZE@68525|delta/epsilon subdivisions,2X61B@28221|Deltaproteobacteria,43W38@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WH1_k127_6039853_1	28072.Nos7524_1356	1.596e-81	273.0	COG3321@1|root,COG3321@2|Bacteria,1G1IB@1117|Cyanobacteria,1HJKD@1161|Nostocales	1117|Cyanobacteria	IQ	TIGRFAM Polyketide-type polyunsaturated fatty acid synthase, PfaA	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
WH1_k127_6039853_2	28072.Nos7524_1356	2.911e-71	245.0	COG3321@1|root,COG3321@2|Bacteria,1G1IB@1117|Cyanobacteria,1HJKD@1161|Nostocales	1117|Cyanobacteria	IQ	TIGRFAM Polyketide-type polyunsaturated fatty acid synthase, PfaA	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
WH1_k127_6039853_0	1242864.D187_000739	3.412e-100	329.0	COG1940@1|root,COG1940@2|Bacteria,1R7YN@1224|Proteobacteria,42QSZ@68525|delta/epsilon subdivisions,2WN50@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GK	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
WH1_k127_6045207_2	379066.GAU_1245	2.553e-09	63.0	COG0392@1|root,COG0392@2|Bacteria,1ZT5W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WH1_k127_6045207_4	7245.FBpp0260894	0.0007768	49.0	2D82N@1|root,2T8G1@2759|Eukaryota,3930P@33154|Opisthokonta,3C8AX@33208|Metazoa,3DPBM@33213|Bilateria,425JT@6656|Arthropoda,3SV54@50557|Insecta,4587U@7147|Diptera,45Z7T@7214|Drosophilidae	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6045207_0	324602.Caur_3475	1.229e-140	458.0	COG0438@1|root,COG0438@2|Bacteria,2G84C@200795|Chloroflexi,375HH@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11
WH1_k127_6045207_1	926569.ANT_15880	1.287e-17	96.0	COG0500@1|root,COG2226@2|Bacteria,2G8SE@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WH1_k127_606245_0	926569.ANT_12750	1.181e-123	408.0	COG4277@1|root,COG4277@2|Bacteria,2G5JR@200795|Chloroflexi	200795|Chloroflexi	S	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
WH1_k127_6064976_0	926569.ANT_22870	8.825e-68	237.0	COG0213@1|root,COG0213@2|Bacteria,2G64G@200795|Chloroflexi	200795|Chloroflexi	F	PFAM glycosyl transferase family 3	pdp	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
WH1_k127_6113192_0	1430440.MGMSRv2_1025	2.442e-48	188.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TRHH@28211|Alphaproteobacteria,2JZBD@204441|Rhodospirillales	204441|Rhodospirillales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WH1_k127_6113192_2	153948.NAL212_2815	2.029e-07	63.0	COG2197@1|root,COG2197@2|Bacteria,1PE8K@1224|Proteobacteria,2WBIW@28216|Betaproteobacteria,3745X@32003|Nitrosomonadales	28216|Betaproteobacteria	K	SMART Signal transduction response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH1_k127_6113192_1	926569.ANT_13880	1.353e-19	91.0	2EU69@1|root,33MNV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_612460_0	316274.Haur_0606	1.456e-76	273.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,2GBI0@200795|Chloroflexi,3766M@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
WH1_k127_612460_1	316274.Haur_1591	1.027e-16	87.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH1_k127_6127163_0	266117.Rxyl_2774	4.311e-31	137.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria	201174|Actinobacteria	J	protein some members contain a von Willebrand factor type A vWA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WH1_k127_6128505_2	1206732.BAGD01000065_gene2481	1.749e-05	48.0	COG1853@1|root,COG1853@2|Bacteria,2GPJS@201174|Actinobacteria,4G0R9@85025|Nocardiaceae	201174|Actinobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,HMGL-like
WH1_k127_6128505_1	926569.ANT_04450	4.882e-48	179.0	COG2078@1|root,COG2078@2|Bacteria	2|Bacteria	S	ferrous iron binding	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
WH1_k127_6128505_0	316274.Haur_3042	9.723e-98	324.0	COG1600@1|root,COG1600@2|Bacteria,2G6A0@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S double cluster binding domain	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Dehalogenase,Fer4_16,HEAT_2
WH1_k127_6145833_0	671143.DAMO_0407	5.276e-255	799.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	AA_permease_2
WH1_k127_6145833_1	1206733.BAGC01000042_gene2191	5.995e-68	250.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4FUQS@85025|Nocardiaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	kdpE	GO:0008150,GO:0040007	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WH1_k127_6145833_2	485913.Krac_9793	2.777e-65	232.0	COG0642@1|root,COG2205@2|Bacteria,2G6KS@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF,HATPase_c,HisKA
WH1_k127_6154845_0	926569.ANT_09030	1.726e-46	169.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2G6K4@200795|Chloroflexi	200795|Chloroflexi	H	phosphoenolpyruvate synthase	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WH1_k127_6154845_1	1313172.YM304_04440	1.208e-22	103.0	2AAWD@1|root,3109H@2|Bacteria,2IG0D@201174|Actinobacteria	201174|Actinobacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
WH1_k127_6154845_2	82508.K1VDK6	3.775e-07	54.0	2AAWD@1|root,2SAUR@2759|Eukaryota,39YPR@33154|Opisthokonta,3NYJM@4751|Fungi	4751|Fungi	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
WH1_k127_6156799_3	383372.Rcas_2773	3.921e-13	75.0	COG1404@1|root,COG1404@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Peptidase_S8
WH1_k127_6156799_2	485916.Dtox_3658	4.336e-22	100.0	COG1724@1|root,COG1724@2|Bacteria,1VKIY@1239|Firmicutes,24UGP@186801|Clostridia	186801|Clostridia	N	periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
WH1_k127_6156799_1	269797.Mbar_A2369	1.042e-26	111.0	COG1598@1|root,arCOG02411@2157|Archaea,2Y4NR@28890|Euryarchaeota,2NB66@224756|Methanomicrobia	224756|Methanomicrobia	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
WH1_k127_6156799_0	926569.ANT_02930	4.23e-54	194.0	COG1284@1|root,COG1284@2|Bacteria,2G6SY@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
WH1_k127_6159689_0	1210884.HG799467_gene13174	4.614e-27	127.0	COG1807@1|root,COG1807@2|Bacteria,2IZFZ@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WH1_k127_6165129_1	926569.ANT_00470	1.866e-85	289.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WH1_k127_6165129_2	926569.ANT_23190	3.773e-80	283.0	COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
WH1_k127_6165129_0	926569.ANT_28150	7.781e-96	325.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	200795|Chloroflexi	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
WH1_k127_6168979_0	1120950.KB892823_gene549	1.507e-171	548.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
WH1_k127_618273_1	926550.CLDAP_09050	2.337e-73	259.0	COG0619@1|root,COG0619@2|Bacteria,2G6TZ@200795|Chloroflexi	200795|Chloroflexi	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
WH1_k127_618273_0	926550.CLDAP_09040	2.175e-219	702.0	COG1122@1|root,COG1122@2|Bacteria,2G5RY@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	ecfA	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
WH1_k127_618273_2	1122221.JHVI01000016_gene1609	2.941e-67	231.0	COG1028@1|root,COG1028@2|Bacteria,1WIMS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH1_k127_6206665_0	926550.CLDAP_18870	4.106e-106	374.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2G6G7@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
WH1_k127_6206665_1	290317.Cpha266_1585	3.988e-75	265.0	COG3621@1|root,COG3621@2|Bacteria	2|Bacteria	AT	Patatin-like phospholipase	-	-	-	ko:K06900	-	-	-	-	ko00000	-	-	-	DUF1735,Laminin_G_3,Patatin
WH1_k127_6229691_3	1480694.DC28_09230	1.164e-10	64.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,2J5CT@203691|Spirochaetes	203691|Spirochaetes	T	HD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD
WH1_k127_6229691_1	926550.CLDAP_24330	4.36e-59	214.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	2.1.1.6	ko:K00545	ko00140,ko00350,ko00965,ko01100,ko04728,map00140,map00350,map00965,map01100,map04728	-	R02534,R02920,R03304,R04301,R04762,R04764,R04881,R04887	RC00003,RC00392	ko00000,ko00001,ko01000,ko04147	-	-	-	Methyltransf_3
WH1_k127_6229691_0	187272.Mlg_2259	1.957e-98	329.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,1RPYA@1236|Gammaproteobacteria,1X0WW@135613|Chromatiales	135613|Chromatiales	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
WH1_k127_6229691_2	706587.Desti_5213	8.631e-21	93.0	COG1598@1|root,COG1598@2|Bacteria,1NDHG@1224|Proteobacteria,432RS@68525|delta/epsilon subdivisions,2WXV3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6235817_0	1521187.JPIM01000067_gene1074	1.247e-161	539.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2GBRR@200795|Chloroflexi,376B2@32061|Chloroflexia	32061|Chloroflexia	D	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like,VWA,VWA_2
WH1_k127_6235817_1	357808.RoseRS_1890	2.149e-60	226.0	COG2304@1|root,COG2304@2|Bacteria,2GABP@200795|Chloroflexi,37510@32061|Chloroflexia	32061|Chloroflexia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
WH1_k127_6237720_2	926569.ANT_18430	3.969e-17	86.0	COG1872@1|root,COG1872@2|Bacteria,2G7H4@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
WH1_k127_6237720_3	1150474.JQJI01000005_gene294	6.486e-08	58.0	COG0762@1|root,COG0762@2|Bacteria,2GDIQ@200918|Thermotogae	200918|Thermotogae	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
WH1_k127_6237720_0	326427.Cagg_1865	2.42e-63	226.0	COG0325@1|root,COG0325@2|Bacteria,2G6F1@200795|Chloroflexi,375I2@32061|Chloroflexia	32061|Chloroflexia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
WH1_k127_6237720_1	926569.ANT_18460	1.491e-53	194.0	COG1496@1|root,COG1496@2|Bacteria,2G6N5@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
WH1_k127_6267619_0	471853.Bcav_1908	4.102e-57	210.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WH1_k127_6267619_1	880073.Calab_1330	5.079e-54	197.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	plsC2	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
WH1_k127_6267619_2	357808.RoseRS_4016	1.219e-50	188.0	COG1266@1|root,COG1266@2|Bacteria,2GBWM@200795|Chloroflexi,37745@32061|Chloroflexia	32061|Chloroflexia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WH1_k127_6271642_0	479434.Sthe_3156	1.038e-75	259.0	COG0803@1|root,COG0803@2|Bacteria,2G8F6@200795|Chloroflexi,27XHP@189775|Thermomicrobia	200795|Chloroflexi	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09818,ko:K11707	ko02010,map02010	M00243,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ZnuA
WH1_k127_6271642_1	383372.Rcas_3322	1.701e-51	186.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,375K6@32061|Chloroflexia	32061|Chloroflexia	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
WH1_k127_627344_3	926569.ANT_25450	1.034e-39	149.0	COG2896@1|root,COG2896@2|Bacteria,2G5JT@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
WH1_k127_627344_2	926569.ANT_03650	1.46e-50	184.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	-	R02029,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
WH1_k127_627344_1	926569.ANT_03640	1.382e-67	238.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
WH1_k127_627344_0	926569.ANT_03630	8.367e-92	311.0	COG5322@1|root,COG5322@2|Bacteria,2G8N0@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Shikimate quinate 5-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_DH
WH1_k127_627344_4	525904.Tter_0098	7.566e-29	117.0	COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	entS	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
WH1_k127_6277002_1	926569.ANT_30540	1.256e-109	369.0	2EZVX@1|root,33T0B@2|Bacteria,2G87X@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6277002_0	926569.ANT_08530	1.163e-125	409.0	COG1087@1|root,COG1087@2|Bacteria,2G8A8@200795|Chloroflexi	200795|Chloroflexi	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WH1_k127_6277002_2	926569.ANT_13190	1.471e-42	169.0	COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WH1_k127_6278408_0	324602.Caur_1651	1.077e-80	304.0	COG0642@1|root,COG2203@1|root,COG3920@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3920@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,GGDEF,HATPase_c,HisKA,HisKA_3,HisKA_7TM,PAS_4,PAS_8,PAS_9,Response_reg
WH1_k127_6278408_2	1449351.RISW2_12610	1.599e-08	69.0	COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,2U595@28211|Alphaproteobacteria,4KMIY@93682|Roseivivax	28211|Alphaproteobacteria	T	GAF domain	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
WH1_k127_6278408_1	926569.ANT_09170	1.234e-43	184.0	COG1956@1|root,COG2202@1|root,COG2203@1|root,COG2770@1|root,COG3437@1|root,COG1956@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2770@2|Bacteria,COG3437@2|Bacteria,2G7KX@200795|Chloroflexi	2|Bacteria	T	HD domain	yebR	-	1.8.4.14,3.1.3.3,4.6.1.1	ko:K01768,ko:K02584,ko:K02660,ko:K07315,ko:K08968,ko:K17763	ko00230,ko00270,ko02020,ko02025,ko04113,ko04213,map00230,map00270,map02020,map02025,map04113,map04213	M00695	R00089,R00434,R02025	RC00295,RC00639	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044,ko03000,ko03021	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HD_5,HisKA,PAS,PAS_3,PAS_4,PAS_9,STAS,SpoIIE,dCache_1
WH1_k127_6278900_6	864051.BurJ1DRAFT_3963	1.554e-05	50.0	COG0642@1|root,COG2204@1|root,COG0642@2|Bacteria,COG2204@2|Bacteria,1NXDJ@1224|Proteobacteria,2W1GY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CHASE,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_7,PAS_8,Response_reg
WH1_k127_6278900_1	1128421.JAGA01000002_gene254	2.642e-90	318.0	COG0534@1|root,COG0534@2|Bacteria,2NPBA@2323|unclassified Bacteria	2|Bacteria	V	MATE efflux family protein	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
WH1_k127_6278900_3	1356852.N008_01905	2.84e-32	135.0	COG0494@1|root,COG0494@2|Bacteria,4NNGW@976|Bacteroidetes,47PNR@768503|Cytophagia	976|Bacteroidetes	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WH1_k127_6278900_2	1173029.JH980292_gene1965	1.962e-36	141.0	COG1832@1|root,COG1832@2|Bacteria,1G704@1117|Cyanobacteria,1HBUX@1150|Oscillatoriales	1117|Cyanobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
WH1_k127_6278900_0	44060.JODL01000002_gene2325	7.925e-147	476.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
WH1_k127_6278900_4	926550.CLDAP_17520	6.095e-14	84.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WH1_k127_6283041_1	926550.CLDAP_15350	6.076e-98	334.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
WH1_k127_6283041_0	880073.Calab_0989	8.237e-159	507.0	COG0667@1|root,COG0667@2|Bacteria,2NP23@2323|unclassified Bacteria	2|Bacteria	C	Aldo/keto reductase family	yghZ	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
WH1_k127_6283041_2	868131.MSWAN_0806	1.292e-89	303.0	COG1741@1|root,arCOG02935@2157|Archaea,2XU8Z@28890|Euryarchaeota	28890|Euryarchaeota	S	Belongs to the Pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
WH1_k127_6283041_3	192952.MM_1264	1.055e-21	102.0	COG5513@1|root,arCOG03547@2157|Archaea,2Y4G7@28890|Euryarchaeota,2NB6K@224756|Methanomicrobia	224756|Methanomicrobia	G	serine-type aminopeptidase activity	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	-
WH1_k127_6295528_1	570268.ANBB01000035_gene2393	3.834e-11	74.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4EIZZ@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH1_k127_6295528_2	381666.PHG265	1.427e-09	72.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,1K2VF@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	narX	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA_3,PilJ
WH1_k127_6295528_0	379066.GAU_3352	6.662e-32	128.0	COG1528@1|root,COG1528@2|Bacteria,1ZUFX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Rubrerythrin	-	-	1.16.3.1	ko:K22336	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
WH1_k127_6295773_4	1114959.SZMC14600_13684	0.0008715	51.0	COG3170@1|root,COG3170@2|Bacteria,2GJWK@201174|Actinobacteria,4E2YJ@85010|Pseudonocardiales	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6295773_0	526225.Gobs_3437	5.628e-41	160.0	COG2197@1|root,COG2197@2|Bacteria,2IG2E@201174|Actinobacteria,4EVZB@85013|Frankiales	201174|Actinobacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH1_k127_6295773_2	1009370.ALO_09524	2.477e-13	78.0	COG4242@1|root,COG4242@2|Bacteria,1TSFA@1239|Firmicutes,4H3KH@909932|Negativicutes	909932|Negativicutes	PQ	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
WH1_k127_6295773_1	179408.Osc7112_1843	7.201e-35	135.0	2DNRM@1|root,32YT2@2|Bacteria,1G8FD@1117|Cyanobacteria,1HD5I@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
WH1_k127_6295773_3	671143.DAMO_1089	6.638e-12	69.0	2C5EY@1|root,32YQJ@2|Bacteria,2NREI@2323|unclassified Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
WH1_k127_6298478_0	926550.CLDAP_09690	2.991e-53	203.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
WH1_k127_6298738_1	649747.HMPREF0083_00332	2.807e-08	57.0	COG0824@1|root,COG0824@2|Bacteria,1V6GS@1239|Firmicutes,4HJ05@91061|Bacilli,26XZV@186822|Paenibacillaceae	91061|Bacilli	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
WH1_k127_6298738_0	706587.Desti_1835	2.226e-232	731.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,43CGH@68525|delta/epsilon subdivisions,2WJ3J@28221|Deltaproteobacteria,2MS4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	EQ	Hydantoinase B/oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
WH1_k127_6299611_0	1089550.ATTH01000001_gene925	6.8e-79	274.0	COG0491@1|root,COG0491@2|Bacteria,4NHXR@976|Bacteroidetes,1FJDJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
WH1_k127_6299611_1	287.DR97_678	3.178e-13	79.0	COG1679@1|root,COG1786@1|root,COG1679@2|Bacteria,COG1786@2|Bacteria,1NFH4@1224|Proteobacteria,1S4TW@1236|Gammaproteobacteria,1YCQX@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF126,DUF521
WH1_k127_6301703_0	926569.ANT_28330	1.721e-147	487.0	COG0608@1|root,COG0608@2|Bacteria,2G7JK@200795|Chloroflexi	200795|Chloroflexi	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WH1_k127_6319794_0	604331.AUHY01000023_gene1652	4.8e-76	269.0	COG1922@1|root,COG1922@2|Bacteria,1WJJ7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Glycosyl transferase WecB/TagA/CpsF family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
WH1_k127_6319794_1	926569.ANT_11900	4.7e-58	217.0	COG5662@1|root,COG5662@2|Bacteria,2GBKH@200795|Chloroflexi	200795|Chloroflexi	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
WH1_k127_6345101_1	926569.ANT_09720	1.651e-11	66.0	COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
WH1_k127_6345101_2	484770.UFO1_2942	1.563e-06	54.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,4H4Q7@909932|Negativicutes	909932|Negativicutes	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
WH1_k127_6345101_0	926569.ANT_09720	6.644e-31	128.0	COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
WH1_k127_6350572_1	926560.KE387023_gene1976	8.773e-66	239.0	COG3940@1|root,COG3940@2|Bacteria,1WM1C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
WH1_k127_6350572_2	926569.ANT_00140	6.728e-46	170.0	COG1959@1|root,COG1959@2|Bacteria,2G8ZH@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
WH1_k127_6350572_0	926569.ANT_24720	8.138e-81	282.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
WH1_k127_6355985_0	326427.Cagg_2827	8.8e-14	84.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi,375E4@32061|Chloroflexia	32061|Chloroflexia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
WH1_k127_635749_1	1501230.ET33_29530	2.374e-72	266.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,26RMX@186822|Paenibacillaceae	91061|Bacilli	G	Glycoside hydrolase family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
WH1_k127_635749_0	926569.ANT_13830	6.961e-77	264.0	COG2738@1|root,COG2738@2|Bacteria,2G6KQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
WH1_k127_6369659_0	1150864.MILUP08_42652	1.325e-19	104.0	COG0433@1|root,COG0433@2|Bacteria,2H4H2@201174|Actinobacteria,4D9D6@85008|Micromonosporales	201174|Actinobacteria	S	Type IV secretion-system coupling protein DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,TraG-D_C,TrwB_AAD_bind
WH1_k127_6371679_1	926569.ANT_11830	1.989e-49	194.0	COG2203@1|root,COG3605@1|root,COG3829@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	virA	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K02482,ko:K02584,ko:K07673,ko:K10819	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00471,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,SpoIIE,dCache_1
WH1_k127_6371679_0	926569.ANT_11830	4.917e-80	299.0	COG2203@1|root,COG3605@1|root,COG3829@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	virA	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K02482,ko:K02584,ko:K07673,ko:K10819	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00471,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,SpoIIE,dCache_1
WH1_k127_638774_1	1292035.H476_2154	0.0002006	48.0	COG0860@1|root,COG5492@1|root,COG0860@2|Bacteria,COG5492@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,25TIH@186804|Peptostreptococcaceae	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,Big_2,CW_binding_2,SH3_3
WH1_k127_638774_0	926569.ANT_23770	5.685e-48	179.0	COG4990@1|root,COG4990@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872,LysM,Peptidase_C39,Peptidase_C39_2,Peptidase_C70
WH1_k127_6389941_1	926569.ANT_09800	4.49e-70	244.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil	-	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WH1_k127_6389941_2	926569.ANT_09790	4.651e-31	136.0	COG0597@1|root,COG0597@2|Bacteria,2G740@200795|Chloroflexi	200795|Chloroflexi	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
WH1_k127_6389941_0	635013.TherJR_2465	1.37e-90	307.0	COG0531@1|root,COG0531@2|Bacteria,1TQE1@1239|Firmicutes,249N1@186801|Clostridia,260S4@186807|Peptococcaceae	186801|Clostridia	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
WH1_k127_6390161_0	180332.JTGN01000016_gene988	2.084e-53	204.0	COG0407@1|root,COG0407@2|Bacteria,1VSZ6@1239|Firmicutes,24F3A@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
WH1_k127_6390161_1	641107.CDLVIII_2646	9.812e-49	178.0	COG2206@1|root,COG2206@2|Bacteria,1UZ46@1239|Firmicutes,25FEK@186801|Clostridia,36WIY@31979|Clostridiaceae	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HDOD
WH1_k127_6393554_3	316274.Haur_2376	8.149e-25	108.0	2EM6G@1|root,33EVQ@2|Bacteria,2G9RV@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6393554_1	1128421.JAGA01000003_gene3666	5.985e-163	519.0	COG0473@1|root,COG0473@2|Bacteria	2|Bacteria	CE	3-isopropylmalate dehydrogenase activity	icd	-	1.1.1.41,1.1.1.85	ko:K00030,ko:K00052	ko00020,ko00290,ko00660,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00290,map00660,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00432,M00535	R00709,R00994,R04426,R10052	RC00084,RC00114,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WH1_k127_6393554_0	926569.ANT_25010	1.234e-222	697.0	COG1509@1|root,COG1509@2|Bacteria,2G7ZT@200795|Chloroflexi	200795|Chloroflexi	H	Lysine-2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,LAM_C,Radical_SAM
WH1_k127_6393554_2	926569.ANT_06070	1.073e-64	240.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
WH1_k127_6393554_4	926569.ANT_06070	4.572e-22	102.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
WH1_k127_6398802_0	316274.Haur_0812	9.747e-204	642.0	COG1690@1|root,COG1690@2|Bacteria,2G5NT@200795|Chloroflexi,376I0@32061|Chloroflexia	32061|Chloroflexia	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
WH1_k127_6398802_1	272569.rrnAC0669	2.217e-09	63.0	COG1796@1|root,arCOG00305@2157|Archaea,2XT14@28890|Euryarchaeota,23SYU@183963|Halobacteria	183963|Halobacteria	L	DNA polymerase IV (family X)	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
WH1_k127_6413592_2	485913.Krac_3237	1.724e-18	99.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
WH1_k127_6413592_1	1382306.JNIM01000001_gene2489	7.104e-39	154.0	2C5C8@1|root,345UA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6413592_0	926550.CLDAP_13490	4.799e-219	703.0	COG1205@1|root,COG1403@1|root,COG1205@2|Bacteria,COG1403@2|Bacteria,2G605@200795|Chloroflexi	200795|Chloroflexi	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,HNH,Helicase_C
WH1_k127_6418036_0	926569.ANT_04770	2.528e-81	303.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2G6RU@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
WH1_k127_6436562_0	706587.Desti_0944	2.624e-108	367.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria,2MRYR@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Undecaprenyl-phosphate galactose phosphotransferase	epsL	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
WH1_k127_6439951_2	358220.C380_16230	2.296e-09	62.0	COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,2VNYF@28216|Betaproteobacteria,4AAHI@80864|Comamonadaceae	28216|Betaproteobacteria	E	Extracellular liganD-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WH1_k127_6439951_0	926569.ANT_22320	2.557e-69	252.0	COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi	200795|Chloroflexi	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
WH1_k127_6439951_1	926569.ANT_22310	4.749e-28	125.0	COG0816@1|root,COG0816@2|Bacteria,2G74F@200795|Chloroflexi	200795|Chloroflexi	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
WH1_k127_6439951_3	926569.ANT_22300	2.129e-05	53.0	COG3299@1|root,COG3299@2|Bacteria	2|Bacteria	S	Baseplate J-like protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Baseplate_J,PA14,fn3
WH1_k127_6445614_0	926569.ANT_11950	6.391e-267	834.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi	200795|Chloroflexi	H	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
WH1_k127_6445614_2	1365176.N186_02495	2.182e-13	73.0	COG2442@1|root,arCOG07520@2157|Archaea,2XRG3@28889|Crenarchaeota	28889|Crenarchaeota	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
WH1_k127_6445614_1	1499967.BAYZ01000036_gene2419	9.31e-15	74.0	COG2152@1|root,COG2152@2|Bacteria,2NPB8@2323|unclassified Bacteria	2|Bacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
WH1_k127_6466733_2	604331.AUHY01000011_gene222	3.839e-21	93.0	COG1521@1|root,COG1521@2|Bacteria,1WI0G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
WH1_k127_6466733_0	1128421.JAGA01000002_gene351	5.01e-109	361.0	COG0414@1|root,COG0414@2|Bacteria,2NP0J@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
WH1_k127_6466733_1	324602.Caur_2859	5.62e-47	178.0	COG1893@1|root,COG1893@2|Bacteria	2|Bacteria	H	2-dehydropantoate 2-reductase activity	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
WH1_k127_6473306_0	1298863.AUEP01000007_gene280	3.493e-46	193.0	COG2114@1|root,COG2770@1|root,COG2114@2|Bacteria,COG2770@2|Bacteria,2GJRI@201174|Actinobacteria,4DNYW@85009|Propionibacteriales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1319c	Guanylate_cyc,HAMP
WH1_k127_6490615_0	383372.Rcas_0650	2.598e-116	387.0	COG1134@1|root,COG1134@2|Bacteria,2G6D9@200795|Chloroflexi,37500@32061|Chloroflexia	32061|Chloroflexia	GM	PFAM ABC transporter related	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
WH1_k127_6490615_1	926550.CLDAP_02140	6.689e-63	226.0	COG1682@1|root,COG1682@2|Bacteria,2G6QU@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
WH1_k127_6490615_2	1128421.JAGA01000002_gene1117	1.605e-61	220.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2NPYM@2323|unclassified Bacteria	2|Bacteria	L	Glycosyltransferase like family 2	gumK	-	2.4.1.264	ko:K07011,ko:K13659	-	-	R09732	RC00005,RC00049	ko00000,ko01000,ko01003	-	GT70	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
WH1_k127_649674_0	357808.RoseRS_2842	1.053e-20	106.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,2G8CK@200795|Chloroflexi,3776C@32061|Chloroflexia	32061|Chloroflexia	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
WH1_k127_649674_1	1220534.B655_2427	3.347e-16	91.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,arCOG04001@1|root,arCOG02361@2157|Archaea,arCOG04001@2157|Archaea,arCOG06537@2157|Archaea,arCOG06918@2157|Archaea	2157|Archaea	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	BAT,GAF_2,GAF_3,HATPase_c,HTH_10,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_8,PAS_9,PocR,Response_reg
WH1_k127_6497477_0	1521187.JPIM01000003_gene3024	1.692e-96	328.0	COG1609@1|root,COG1609@2|Bacteria,2G6DT@200795|Chloroflexi,376ZH@32061|Chloroflexia	32061|Chloroflexia	K	periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WH1_k127_65023_0	1122622.ATWJ01000007_gene1753	1.642e-11	78.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4FFAH@85021|Intrasporangiaceae	201174|Actinobacteria	Q	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WH1_k127_6502596_0	1121430.JMLG01000030_gene1612	2.673e-110	372.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,260G0@186807|Peptococcaceae	186801|Clostridia	E	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
WH1_k127_6502596_1	1000565.METUNv1_01440	7.632e-39	155.0	COG0560@1|root,COG0560@2|Bacteria	2|Bacteria	E	Phosphoserine phosphatase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase
WH1_k127_6502596_2	324602.Caur_2175	2.591e-06	56.0	2BEFV@1|root,32CHX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_650639_2	644282.Deba_2698	1.635e-17	85.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase	manAC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
WH1_k127_650639_0	1128421.JAGA01000003_gene3142	6.044e-118	389.0	COG0758@1|root,COG0758@2|Bacteria,2NP2V@2323|unclassified Bacteria	2|Bacteria	LU	DNA recombination-mediator protein A	dprA	-	5.99.1.2	ko:K03168,ko:K04096	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_processg_A
WH1_k127_650639_1	926569.ANT_16020	1.491e-27	116.0	COG0806@1|root,COG0806@2|Bacteria,2G707@200795|Chloroflexi	200795|Chloroflexi	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
WH1_k127_6507132_0	1254432.SCE1572_36630	5.905e-145	465.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,42MKW@68525|delta/epsilon subdivisions,2WKFI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the arginase family	-	-	3.5.3.11,3.5.3.17	ko:K01480,ko:K18459	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
WH1_k127_6510250_2	287.DR97_1873	1.229e-06	52.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1YCX6@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	iYL1228.KPN_03597,ic_1306.c3945	polyprenyl_synt
WH1_k127_6510250_0	1382356.JQMP01000003_gene2210	3.656e-82	286.0	COG0463@1|root,COG1216@1|root,COG0463@2|Bacteria,COG1216@2|Bacteria,2G6JZ@200795|Chloroflexi,27XJJ@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
WH1_k127_6510250_1	1382356.JQMP01000003_gene2211	8.22e-25	109.0	COG0438@1|root,COG0438@2|Bacteria,2G6AR@200795|Chloroflexi,27Y71@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
WH1_k127_6512163_0	10224.XP_002735311.2	2.597e-45	172.0	COG0329@1|root,2QWNS@2759|Eukaryota,399HY@33154|Opisthokonta,3BGNT@33208|Metazoa,3CUM9@33213|Bilateria	33208|Metazoa	E	4-hydroxy-2-oxoglutarate aldolase activity	HOGA1	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006081,GO:0006082,GO:0006090,GO:0006520,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008700,GO:0009056,GO:0009058,GO:0009063,GO:0009436,GO:0009987,GO:0016053,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0016833,GO:0019470,GO:0019471,GO:0019752,GO:0031974,GO:0032787,GO:0033609,GO:0042219,GO:0042802,GO:0042803,GO:0042866,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046185,GO:0046394,GO:0046395,GO:0046487,GO:0046983,GO:0070013,GO:0071704,GO:0072329,GO:0072330,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606	4.1.3.16	ko:K18123	ko00330,ko00630,ko01100,map00330,map00630,map01100	-	R00470,R00471	RC00307,RC00308	ko00000,ko00001,ko01000	-	-	-	DHDPS
WH1_k127_6512163_1	1463934.JOCF01000069_gene5092	4.508e-24	110.0	COG0501@1|root,COG0501@2|Bacteria,2GKJQ@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
WH1_k127_6536559_0	1382356.JQMP01000003_gene1464	4.31e-40	165.0	COG2730@1|root,COG2730@2|Bacteria,2GBH8@200795|Chloroflexi,27Y4J@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
WH1_k127_6541693_1	448385.sce1866	8.392e-56	201.0	COG1819@1|root,COG1819@2|Bacteria,1MVI7@1224|Proteobacteria,42UK8@68525|delta/epsilon subdivisions,2WQG7@28221|Deltaproteobacteria,2YXKW@29|Myxococcales	28221|Deltaproteobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_transf_28,UDPGT
WH1_k127_6541693_0	926569.ANT_02850	3.266e-169	543.0	COG1236@1|root,COG1236@2|Bacteria,2G62G@200795|Chloroflexi	200795|Chloroflexi	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
WH1_k127_6543946_2	926569.ANT_25030	2.414e-20	94.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
WH1_k127_6543946_0	926569.ANT_25040	2.136e-132	433.0	COG0484@1|root,COG0484@2|Bacteria,2G5NV@200795|Chloroflexi	200795|Chloroflexi	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WH1_k127_6543946_1	926569.ANT_25050	2.007e-126	411.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WH1_k127_6544972_2	706587.Desti_2949	3.441e-169	541.0	COG0069@1|root,COG1145@1|root,COG0069@2|Bacteria,COG1145@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Glu_synthase
WH1_k127_6544972_7	706587.Desti_2948	3.08e-75	271.0	COG0069@1|root,COG0069@2|Bacteria	2|Bacteria	E	glutamate synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Glu_synthase
WH1_k127_6544972_3	926569.ANT_08710	1.833e-167	548.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi	200795|Chloroflexi	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
WH1_k127_6544972_4	926569.ANT_09200	9.541e-152	497.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WH1_k127_6544972_10	926569.ANT_08290	1.303e-38	151.0	COG0838@1|root,COG0838@2|Bacteria,2G78Y@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
WH1_k127_6544972_6	926569.ANT_08300	6.349e-87	289.0	COG0377@1|root,COG0377@2|Bacteria,2G6GB@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB1	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
WH1_k127_6544972_9	926569.ANT_08310	3.142e-47	176.0	COG0852@1|root,COG0852@2|Bacteria,2G6WD@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
WH1_k127_6544972_1	926569.ANT_08320	5.217e-178	567.0	COG0649@1|root,COG0649@2|Bacteria,2G5MM@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
WH1_k127_6544972_8	926569.ANT_08330	3.73e-48	177.0	COG1905@1|root,COG1905@2|Bacteria,2G70Y@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
WH1_k127_6544972_0	926569.ANT_08340	1.252e-179	571.0	COG1894@1|root,COG1894@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
WH1_k127_6544972_5	926569.ANT_08350	7.014e-97	320.0	COG0243@1|root,COG1034@1|root,COG0243@2|Bacteria,COG1034@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WH1_k127_6556862_0	1000565.METUNv1_02915	4.248e-66	235.0	COG2304@1|root,COG2374@1|root,COG2304@2|Bacteria,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,2VK7U@28216|Betaproteobacteria,2KY0R@206389|Rhodocyclales	206389|Rhodocyclales	Q	Endonuclease/Exonuclease/phosphatase family	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos
WH1_k127_6556862_2	68570.DC74_4613	2.144e-21	101.0	COG3787@1|root,COG3787@2|Bacteria,2IHVY@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0306 family	-	-	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
WH1_k127_6556862_1	76114.ebA5680	7.247e-65	228.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	-	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
WH1_k127_6562055_1	479434.Sthe_1787	6.603e-09	68.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,27XT2@189775|Thermomicrobia	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
WH1_k127_6562055_0	509191.AEDB02000002_gene1241	3.292e-20	101.0	2EXYB@1|root,33R7F@2|Bacteria,1VRIG@1239|Firmicutes,24D3X@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
WH1_k127_6575872_0	68170.KL590499_gene4927	7.482e-157	559.0	COG2931@1|root,COG2931@2|Bacteria,2GR03@201174|Actinobacteria,4E8ZQ@85010|Pseudonocardiales	201174|Actinobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,HemolysinCabind,Peptidase_M91,fn3
WH1_k127_6577055_0	926569.ANT_11500	1.016e-106	362.0	COG1807@1|root,COG1807@2|Bacteria,2G991@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6577055_1	926569.ANT_26880	9.786e-67	248.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6577055_3	926569.ANT_11570	1.475e-42	175.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
WH1_k127_6587808_1	357808.RoseRS_1504	1.329e-53	197.0	COG2717@1|root,COG2717@2|Bacteria,2G6WP@200795|Chloroflexi,375NC@32061|Chloroflexia	32061|Chloroflexia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
WH1_k127_6587808_0	357808.RoseRS_1505	4.731e-133	432.0	COG2041@1|root,COG2041@2|Bacteria,2G618@200795|Chloroflexi,375BB@32061|Chloroflexia	32061|Chloroflexia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
WH1_k127_6587808_3	1128421.JAGA01000001_gene2214	8.825e-08	55.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
WH1_k127_6587808_2	926569.ANT_11110	3.805e-40	156.0	COG1082@1|root,COG1082@2|Bacteria,2G5V7@200795|Chloroflexi	200795|Chloroflexi	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
WH1_k127_6590073_1	1210884.HG799465_gene11655	1.116e-14	76.0	COG3635@1|root,COG3635@2|Bacteria,2IY5S@203682|Planctomycetes	203682|Planctomycetes	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
WH1_k127_6590073_0	926569.ANT_13260	1.825e-105	354.0	COG0391@1|root,COG0391@2|Bacteria,2G5MJ@200795|Chloroflexi	200795|Chloroflexi	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
WH1_k127_6590846_0	309799.DICTH_0428	7.452e-214	696.0	COG0677@1|root,COG1372@1|root,COG0677@2|Bacteria,COG1372@2|Bacteria	2|Bacteria	L	intein-mediated protein splicing	wbpA1	-	1.1.1.136,1.1.98.6,1.17.4.1,3.5.4.13,6.5.1.3	ko:K00526,ko:K01494,ko:K02474,ko:K13015,ko:K14415,ko:K21636	ko00230,ko00240,ko00520,ko01100,map00230,map00240,map00520,map01100	M00053	R00421,R00568,R02017,R02018,R02019,R02024,R02325,R06894,R11633,R11634,R11635,R11636	RC00074,RC00291,RC00613	ko00000,ko00001,ko00002,ko01000,ko01005,ko03016,ko03400	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WH1_k127_6596884_0	240292.Ava_2971	0.0006856	52.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HKN5@1161|Nostocales	1117|Cyanobacteria	S	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,WD40
WH1_k127_6607969_0	926550.CLDAP_03240	2.799e-24	114.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	-
WH1_k127_6641099_1	926569.ANT_01110	1.258e-77	275.0	COG0845@1|root,COG0845@2|Bacteria,2G8X1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
WH1_k127_6641099_0	926550.CLDAP_00330	8.02e-110	358.0	COG2723@1|root,COG2723@2|Bacteria,2G67P@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
WH1_k127_6665989_0	926569.ANT_17250	2.022e-107	357.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi	200795|Chloroflexi	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WH1_k127_6665989_2	926569.ANT_04120	2.402e-28	119.0	COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi	200795|Chloroflexi	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
WH1_k127_6665989_1	671143.DAMO_1522	4.944e-38	149.0	COG2267@1|root,COG2267@2|Bacteria,2NPTF@2323|unclassified Bacteria	2|Bacteria	I	Alpha/beta hydrolase family	mhpC	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
WH1_k127_6674106_2	1121377.KB906400_gene1221	7.223e-15	80.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4111,NTP_transf_2
WH1_k127_6674106_0	1122611.KB903946_gene864	3.493e-55	205.0	COG0454@1|root,COG0456@2|Bacteria,2INZ5@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WH1_k127_6674106_1	357808.RoseRS_3986	1.114e-21	96.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,375K6@32061|Chloroflexia	32061|Chloroflexia	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
WH1_k127_6690518_1	765910.MARPU_00280	9.842e-112	374.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,1RMAV@1236|Gammaproteobacteria,1WZAK@135613|Chromatiales	135613|Chromatiales	U	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
WH1_k127_6690518_2	378806.STAUR_7280	1.03e-102	353.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,42M9Y@68525|delta/epsilon subdivisions,2WTUE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
WH1_k127_6690518_3	1392487.JIAD01000001_gene1661	5.189e-07	53.0	COG0038@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0569@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,25VA0@186806|Eubacteriaceae	186801|Clostridia	P	Chloride transporter, ClC family	clcA	-	-	-	-	-	-	-	-	-	-	-	TrkA_C,Voltage_CLC
WH1_k127_6690518_0	926550.CLDAP_09870	2.615e-190	612.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	ycjM	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
WH1_k127_6694924_5	66875.JODY01000034_gene2947	4.28e-16	80.0	COG0793@1|root,COG0793@2|Bacteria,2GKRP@201174|Actinobacteria	201174|Actinobacteria	M	Peptidase, S41	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
WH1_k127_6694924_2	292459.STH340	3.158e-48	179.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
WH1_k127_6694924_1	243231.GSU1223	3.883e-59	214.0	29FVD@1|root,302T2@2|Bacteria,1RKWC@1224|Proteobacteria,42TAZ@68525|delta/epsilon subdivisions,2WP8E@28221|Deltaproteobacteria,43T6K@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6694924_4	314230.DSM3645_05470	3.503e-29	125.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
WH1_k127_6694924_3	1173028.ANKO01000042_gene839	1.436e-31	126.0	COG2442@1|root,COG2442@2|Bacteria,1G7PT@1117|Cyanobacteria,1HC98@1150|Oscillatoriales	1117|Cyanobacteria	K	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
WH1_k127_6694924_0	1521187.JPIM01000019_gene393	2.576e-114	378.0	COG2352@1|root,COG2352@2|Bacteria,2G62H@200795|Chloroflexi,3755U@32061|Chloroflexia	32061|Chloroflexia	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
WH1_k127_6705677_1	926569.ANT_22300	4.6e-29	133.0	COG3299@1|root,COG3299@2|Bacteria	2|Bacteria	S	Baseplate J-like protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Baseplate_J,PA14,fn3
WH1_k127_6705677_0	926550.CLDAP_11380	2.952e-65	230.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WH1_k127_6730255_1	926569.ANT_16180	2.807e-92	313.0	COG0524@1|root,COG0524@2|Bacteria,2G7YR@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	adoK	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
WH1_k127_6730255_0	926550.CLDAP_17710	1.223e-123	407.0	COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
WH1_k127_6730671_2	324602.Caur_1111	6.961e-32	127.0	COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi,375EF@32061|Chloroflexia	32061|Chloroflexia	H	PFAM sugar isomerase (SIS)	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
WH1_k127_6730671_0	1380390.JIAT01000010_gene4906	7.727e-57	210.0	COG0491@1|root,COG0491@2|Bacteria,2HGYI@201174|Actinobacteria,4CQY2@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WH1_k127_6730671_1	926569.ANT_13410	1.967e-47	179.0	COG0477@1|root,COG2814@2|Bacteria,2GBP2@200795|Chloroflexi	200795|Chloroflexi	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH1_k127_6737158_0	477974.Daud_0668	2.293e-97	331.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,24CIR@186801|Clostridia,2606N@186807|Peptococcaceae	186801|Clostridia	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WH1_k127_6737158_1	479434.Sthe_2799	2.67e-83	287.0	COG0559@1|root,COG0559@2|Bacteria,2G6M5@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WH1_k127_6737158_2	235909.GK3024	2.534e-74	265.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HE1X@91061|Bacilli,1WEEP@129337|Geobacillus	91061|Bacilli	P	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WH1_k127_6737158_3	667014.Thein_2213	4.045e-31	124.0	COG1541@1|root,COG1541@2|Bacteria,2GH71@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	AMP-binding enzyme C-terminal domain	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
WH1_k127_6737245_0	1206732.BAGD01000103_gene4559	6.906e-20	105.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4FTZW@85025|Nocardiaceae	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH1_k127_6737245_1	1121472.AQWN01000004_gene708	5.086e-12	79.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,2644X@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA_3,sCache_3_2
WH1_k127_6737433_0	47839.CCAU010000009_gene1461	1.567e-90	323.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,23407@1762|Mycobacteriaceae	201174|Actinobacteria	O	assembly protein SufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
WH1_k127_6737433_1	744872.Spica_0323	7.876e-18	93.0	COG0719@1|root,COG0719@2|Bacteria,2J5T1@203691|Spirochaetes	203691|Spirochaetes	O	assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
WH1_k127_6760273_1	1128421.JAGA01000002_gene1381	4.582e-75	276.0	COG0624@1|root,COG0624@2|Bacteria,2NQ4M@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M20/M25/M40	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28,Peptidase_M42
WH1_k127_6760273_2	1121430.JMLG01000003_gene597	4.306e-46	178.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,260MY@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
WH1_k127_6760273_0	926550.CLDAP_12360	1.927e-136	455.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	-	-	3.2.1.21	ko:K05350,ko:K21000	ko00460,ko00500,ko00940,ko01100,ko01110,ko02025,map00460,map00500,map00940,map01100,map01110,map02025	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH39	-	Cellulase,Glyco_hydro_1
WH1_k127_6762979_0	1128421.JAGA01000001_gene2038	1.409e-54	209.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria	2|Bacteria	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,GGDEF,SpoIIE
WH1_k127_6765257_2	926569.ANT_11700	1.338e-48	188.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
WH1_k127_6765257_1	326427.Cagg_0328	4.407e-71	256.0	COG1187@1|root,COG1187@2|Bacteria,2G6HU@200795|Chloroflexi,375DQ@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WH1_k127_6765257_0	926569.ANT_12980	1.955e-138	472.0	COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2
WH1_k127_6777805_0	404589.Anae109_0573	2.85e-144	486.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2WJG7@28221|Deltaproteobacteria,2YUAP@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
WH1_k127_6777805_1	326427.Cagg_1880	2.862e-12	76.0	COG1361@1|root,COG1361@2|Bacteria,2GA09@200795|Chloroflexi,377KM@32061|Chloroflexia	32061|Chloroflexia	M	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
WH1_k127_6777805_2	880073.Calab_2326	0.000151	53.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin-like,SLH,TSP_3
WH1_k127_6777805_3	1123277.KB893206_gene3391	0.000151	53.0	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,4PKCH@976|Bacteroidetes	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SdrD_B
WH1_k127_6788915_4	867845.KI911784_gene3614	2.791e-20	105.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	AAA_16,AAA_22,AAA_35
WH1_k127_6788915_5	525309.HMPREF0494_1506	1.972e-06	60.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,4HUBD@91061|Bacilli,3FC94@33958|Lactobacillaceae	91061|Bacilli	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WH1_k127_6788915_6	263358.VAB18032_23510	4.545e-05	56.0	COG3087@1|root,COG3087@2|Bacteria,2IS4S@201174|Actinobacteria,4DEVE@85008|Micromonosporales	201174|Actinobacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6788915_3	42256.RradSPS_2809	4.583e-34	146.0	2E64T@1|root,330TJ@2|Bacteria,2H60Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6788915_2	485913.Krac_6992	7.911e-37	162.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
WH1_k127_6788915_1	1521187.JPIM01000050_gene3440	4.597e-43	183.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,CHAT,NB-ARC,Pkinase,TPR_12,TPR_7,TPR_8
WH1_k127_6788915_0	926569.ANT_25370	1.11e-56	215.0	COG1664@1|root,COG1664@2|Bacteria,2G79N@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6796664_0	1521187.JPIM01000020_gene234	2.966e-82	278.0	COG0410@1|root,COG0410@2|Bacteria,2G69M@200795|Chloroflexi,374V9@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
WH1_k127_6796664_1	1128421.JAGA01000001_gene2258	6.513e-72	254.0	COG0559@1|root,COG0559@2|Bacteria	2|Bacteria	E	leucine import across plasma membrane	MA20_23490	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WH1_k127_6798102_0	1499967.BAYZ01000161_gene390	8.897e-87	295.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,2NNXD@2323|unclassified Bacteria	2|Bacteria	LV	Eco57I restriction-modification methylase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,HSDR_N,N6_Mtase,TaqI_C
WH1_k127_6821299_0	1385519.N801_12865	1.234e-113	377.0	COG0451@1|root,COG0451@2|Bacteria,2GK8K@201174|Actinobacteria,4FGXM@85021|Intrasporangiaceae	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2,5.1.3.25	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	M00361,M00362,M00632	R00291,R02984,R10279	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
WH1_k127_6821299_1	926550.CLDAP_36320	2.657e-51	187.0	COG0241@1|root,COG0241@2|Bacteria,2G6V8@200795|Chloroflexi	200795|Chloroflexi	E	Histidinol-phosphate phosphatase family protein	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Glycos_transf_2,Hydrolase_like
WH1_k127_6835926_0	926569.ANT_15860	6.443e-290	955.0	COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi	200795|Chloroflexi	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
WH1_k127_6835926_1	926569.ANT_15870	3.116e-45	174.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	PMT_2
WH1_k127_6844716_0	926569.ANT_11700	5.097e-55	199.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
WH1_k127_6844716_1	1273125.Rrhod_2471	4.63e-19	94.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria,4FXX7@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH1_k127_6844896_1	926569.ANT_12000	3.71e-83	283.0	COG0006@1|root,COG0006@2|Bacteria,2G5J6@200795|Chloroflexi	200795|Chloroflexi	C	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WH1_k127_6844896_0	926569.ANT_12010	1.259e-124	407.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi	200795|Chloroflexi	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WH1_k127_6848672_1	604331.AUHY01000011_gene222	1.86e-124	403.0	COG1521@1|root,COG1521@2|Bacteria,1WI0G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
WH1_k127_6848672_0	1122223.KB890700_gene1977	1.08e-170	552.0	COG0452@1|root,COG0452@2|Bacteria,1WIH0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
WH1_k127_6848672_4	1122223.KB890696_gene280	4.097e-09	69.0	2BN1I@1|root,32GMQ@2|Bacteria,1WN4C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6848672_3	926569.ANT_08490	2.819e-26	115.0	COG1664@1|root,COG1664@2|Bacteria,2G7DZ@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
WH1_k127_6848672_2	357808.RoseRS_2190	1.735e-56	203.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
WH1_k127_6861750_0	1128421.JAGA01000002_gene1973	1.142e-317	992.0	COG3250@1|root,COG3250@2|Bacteria,2NNR1@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolases family 2	manB2	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
WH1_k127_6869257_1	104623.Ser39006_04099	1.216e-33	134.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,1RMZB@1236|Gammaproteobacteria,3ZZKJ@613|Serratia	1236|Gammaproteobacteria	IQ	Catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
WH1_k127_6869257_2	43989.cce_1065	9.125e-07	58.0	2E3YV@1|root,32YVT@2|Bacteria,1GA8Z@1117|Cyanobacteria,3KKK5@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6869257_0	706587.Desti_0324	5.834e-205	644.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2WJMB@28221|Deltaproteobacteria,2MQ8V@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
WH1_k127_6869891_2	926569.ANT_30160	1.576e-23	100.0	COG0156@1|root,COG0156@2|Bacteria,2G65Q@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WH1_k127_6869891_1	926569.ANT_27700	5.109e-98	326.0	COG2220@1|root,COG2220@2|Bacteria,2G6KN@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
WH1_k127_6869891_0	1122994.AUFR01000022_gene333	2.136e-154	505.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4DQX3@85009|Propionibacteriales	201174|Actinobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
WH1_k127_6869891_3	926550.CLDAP_11930	4.188e-13	79.0	COG2132@1|root,COG5617@1|root,COG2132@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3,PTPS_related
WH1_k127_6875389_0	1121015.N789_11825	5.061e-74	264.0	COG1571@1|root,COG1571@2|Bacteria,1QVS8@1224|Proteobacteria,1T2IQ@1236|Gammaproteobacteria,1X9DX@135614|Xanthomonadales	135614|Xanthomonadales	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6878160_1	1128421.JAGA01000002_gene1413	2.869e-44	171.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	N6_N4_Mtase,ParBc
WH1_k127_6878160_0	1128421.JAGA01000004_gene2611	2.1e-161	523.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
WH1_k127_6878160_2	767817.Desgi_2396	8.741e-06	49.0	COG0791@1|root,COG0791@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia,2674H@186807|Peptococcaceae	186801|Clostridia	M	Cell wall-associated hydrolase (invasion-associated protein)	spr	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	G5,LysM,NLPC_P60,PG_binding_1
WH1_k127_6892240_1	316274.Haur_4101	5.084e-62	226.0	COG5530@1|root,COG5530@2|Bacteria	2|Bacteria	S	Predicted integral membrane protein (DUF2270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2270
WH1_k127_6892240_3	1121472.AQWN01000008_gene2036	1.769e-16	91.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,24BGW@186801|Clostridia,266TM@186807|Peptococcaceae	186801|Clostridia	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
WH1_k127_6892240_0	926569.ANT_14480	1.559e-93	330.0	COG1975@1|root,COG1975@2|Bacteria,2G6H0@200795|Chloroflexi	200795|Chloroflexi	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
WH1_k127_6892240_4	697281.Mahau_0989	0.0003978	48.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WH1_k127_6892240_2	1002340.AFCF01000031_gene4101	3.937e-23	103.0	COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria,2U51W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Protein of unknown function (DUF2652)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652,Polyketide_cyc2
WH1_k127_6892668_1	926569.ANT_18470	1.139e-52	195.0	COG0625@1|root,COG3815@1|root,COG0625@2|Bacteria,COG3815@2|Bacteria,2G73B@200795|Chloroflexi	200795|Chloroflexi	O	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
WH1_k127_6892668_0	926569.ANT_13960	5.117e-161	523.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WH1_k127_6897315_0	335541.Swol_1646	1.517e-67	242.0	COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,247ZC@186801|Clostridia,42KBW@68298|Syntrophomonadaceae	186801|Clostridia	P	Phosphate transporter family	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
WH1_k127_6897315_1	926569.ANT_30340	2.113e-57	209.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi	200795|Chloroflexi	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WH1_k127_6917995_0	479434.Sthe_3301	4.291e-107	359.0	COG1804@1|root,COG1804@2|Bacteria,2G7MX@200795|Chloroflexi,27YZQ@189775|Thermomicrobia	189775|Thermomicrobia	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
WH1_k127_6917995_1	264732.Moth_1999	5.896e-64	229.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,42J1J@68295|Thermoanaerobacterales	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.1.4,1.17.1.5	ko:K00087,ko:K20447	ko00230,ko00760,ko01100,ko01120,map00230,map00760,map01100,map01120	M00546	R01720,R01768,R02103	RC00143,RC00589	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
WH1_k127_6920634_0	926569.ANT_16740	2.579e-73	259.0	COG1226@1|root,COG1226@2|Bacteria,2G7EI@200795|Chloroflexi	200795|Chloroflexi	P	PFAM TrkA-N domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_C,TrkA_N
WH1_k127_6920634_1	926569.ANT_16760	3.184e-53	197.0	COG0342@1|root,COG0342@2|Bacteria,2G5K5@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WH1_k127_6921490_1	1303518.CCALI_02660	4.986e-67	258.0	COG0457@1|root,COG0457@2|Bacteria	1303518.CCALI_02660|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6921490_0	323261.Noc_0114	4.785e-87	320.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1WX09@135613|Chromatiales	135613|Chromatiales	P	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
WH1_k127_692660_0	1128421.JAGA01000003_gene2987	2.68e-132	430.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2NQG9@2323|unclassified Bacteria	2|Bacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12,Trans_reg_C
WH1_k127_6931618_1	203119.Cthe_0638	6.543e-22	109.0	COG1674@1|root,COG1674@2|Bacteria,1TRA4@1239|Firmicutes,249Z1@186801|Clostridia,3WGYE@541000|Ruminococcaceae	186801|Clostridia	D	FtsK/SpoIIIE family	essC	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FHA,FtsK_SpoIIIE
WH1_k127_6931618_0	324602.Caur_0299	2.049e-22	111.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
WH1_k127_6953650_2	926569.ANT_01830	2.413e-09	61.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WH1_k127_6953650_0	926569.ANT_01840	4.517e-116	387.0	COG0205@1|root,COG0205@2|Bacteria,2G62R@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
WH1_k127_6953650_1	1232410.KI421413_gene773	1.081e-50	188.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
WH1_k127_6958328_0	439235.Dalk_3255	2.268e-49	188.0	COG1807@1|root,COG1807@2|Bacteria,1NIRX@1224|Proteobacteria,4337W@68525|delta/epsilon subdivisions,2WY1C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6962135_0	926569.ANT_05010	3.612e-89	314.0	COG1234@1|root,COG1234@2|Bacteria,2G6YW@200795|Chloroflexi	200795|Chloroflexi	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
WH1_k127_6962135_1	1122222.AXWR01000006_gene2727	5.193e-87	300.0	COG3294@1|root,COG3294@2|Bacteria,1WJ8W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
WH1_k127_6962135_3	926550.CLDAP_23390	5.258e-18	100.0	COG1807@1|root,COG1807@2|Bacteria,2G9BJ@200795|Chloroflexi	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
WH1_k127_6962135_2	1128421.JAGA01000002_gene287	1.027e-78	280.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WH1_k127_6972982_0	1128421.JAGA01000002_gene1392	1.694e-44	175.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9
WH1_k127_6972982_1	1122917.KB899662_gene2386	7.152e-08	59.0	COG0491@1|root,COG0491@2|Bacteria,1V0A9@1239|Firmicutes,4HCJI@91061|Bacilli,26V6H@186822|Paenibacillaceae	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WH1_k127_6981219_2	926569.ANT_01520	8.62e-88	295.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi	200795|Chloroflexi	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
WH1_k127_6981219_0	383372.Rcas_1420	4.73e-120	397.0	COG1239@1|root,COG1239@2|Bacteria,2G5WJ@200795|Chloroflexi,375B3@32061|Chloroflexia	32061|Chloroflexia	H	PFAM magnesium chelatase ChlI subunit	-	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Mg_chelatase,VWA_2
WH1_k127_6981219_1	926569.ANT_05390	5.054e-111	377.0	COG1240@1|root,COG1240@2|Bacteria,2G7UF@200795|Chloroflexi	200795|Chloroflexi	H	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
WH1_k127_6983621_0	926569.ANT_00870	3.902e-60	224.0	COG0457@1|root,COG0457@2|Bacteria,2G94P@200795|Chloroflexi	200795|Chloroflexi	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
WH1_k127_6983621_1	926569.ANT_03890	1.987e-39	161.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_03890|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_6983621_2	926550.CLDAP_35470	2.066e-22	111.0	COG3103@1|root,COG3858@1|root,COG3858@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	MA20_15015	-	-	-	-	-	-	-	-	-	-	-	DUF1236,SH3_3
WH1_k127_6987882_1	666685.R2APBS1_3911	3.537e-104	346.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1SJQ1@1236|Gammaproteobacteria,1X5IA@135614|Xanthomonadales	135614|Xanthomonadales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
WH1_k127_6987882_2	926569.ANT_18070	3.534e-64	223.0	COG0698@1|root,COG0698@2|Bacteria,2G6SM@200795|Chloroflexi	200795|Chloroflexi	G	Ribose/Galactose Isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
WH1_k127_6987882_0	926569.ANT_18060	4.586e-264	842.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,2G67J@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
WH1_k127_7000601_1	1123508.JH636449_gene7420	1.665e-67	234.0	COG2202@1|root,COG4191@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,2IZ70@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
WH1_k127_7000601_0	1123508.JH636449_gene7420	4.881e-81	295.0	COG2202@1|root,COG4191@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,2IZ70@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
WH1_k127_7000601_2	1173026.Glo7428_2204	2.16e-56	201.0	COG0784@1|root,COG0784@2|Bacteria,1GQ4W@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM response regulator receiveR	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WH1_k127_7000601_3	1173026.Glo7428_2204	1.906e-44	165.0	COG0784@1|root,COG0784@2|Bacteria,1GQ4W@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM response regulator receiveR	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WH1_k127_7000601_4	1318628.MARLIPOL_02845	1.867e-35	146.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WH1_k127_7030821_0	926569.ANT_05240	1.606e-111	372.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi	200795|Chloroflexi	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
WH1_k127_7045761_1	1304874.JAFY01000007_gene1752	1.731e-54	207.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GAF,HATPase_c,HisKA,Response_reg
WH1_k127_7045761_0	926550.CLDAP_16480	3.517e-65	241.0	COG0745@1|root,COG1672@1|root,COG0745@2|Bacteria,COG1672@2|Bacteria,2G778@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
WH1_k127_7046035_0	880073.Calab_3450	7.541e-58	222.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE-2	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
WH1_k127_7046035_1	82654.Pse7367_2380	4.008e-35	136.0	COG0618@1|root,COG0618@2|Bacteria,1G3B4@1117|Cyanobacteria,1HA20@1150|Oscillatoriales	1117|Cyanobacteria	S	COGs COG0618 Exopolyphosphatase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_7060730_0	575540.Isop_3152	3.298e-313	981.0	COG0296@1|root,COG0296@2|Bacteria,2IXS1@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
WH1_k127_7060730_1	402777.KB235903_gene1674	3.466e-53	213.0	COG3322@1|root,COG5002@1|root,COG3322@2|Bacteria,COG5002@2|Bacteria,1GQB3@1117|Cyanobacteria,1H7YF@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HATPase_c,HisKA,PAS_9
WH1_k127_7060730_3	65393.PCC7424_4455	0.0002768	48.0	290VB@1|root,2ZNHB@2|Bacteria,1GGNX@1117|Cyanobacteria,3KINJ@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_7060730_2	1499967.BAYZ01000080_gene935	2.494e-49	183.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3
WH1_k127_7065530_0	326427.Cagg_2762	4.884e-115	376.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
WH1_k127_7072095_1	937777.Deipe_0063	4.924e-57	204.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
WH1_k127_7072095_0	1131730.BAVI_16847	2.39e-191	612.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HF4F@91061|Bacilli,1ZQWV@1386|Bacillus	91061|Bacilli	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
WH1_k127_7085067_1	926569.ANT_11790	8.383e-67	236.0	COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
WH1_k127_7085067_0	316274.Haur_1217	1.8e-86	301.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WH1_k127_708993_1	864051.BurJ1DRAFT_2687	1.886e-36	141.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,2VWMP@28216|Betaproteobacteria,1KNZM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WH1_k127_708993_0	926569.ANT_10380	1.437e-154	502.0	COG1694@1|root,COG3956@2|Bacteria,2G5WH@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM MazG family protein	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG,TP_methylase
WH1_k127_708993_2	1122143.AUEG01000010_gene1091	9.264e-18	83.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli,27GAG@186828|Carnobacteriaceae	91061|Bacilli	J	Ribosomal protein S9/S16	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
WH1_k127_7099106_0	378806.STAUR_1535	9.528e-32	134.0	COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,43BJ4@68525|delta/epsilon subdivisions,2WMCV@28221|Deltaproteobacteria,2YXIN@29|Myxococcales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
WH1_k127_7099106_1	502025.Hoch_4690	2.485e-24	109.0	292W5@1|root,2ZQDN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_7101611_3	477974.Daud_0607	1.542e-60	213.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,260PI@186807|Peptococcaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
WH1_k127_7101611_0	926569.ANT_31010	4.965e-99	330.0	COG0528@1|root,COG0528@2|Bacteria,2G5RG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WH1_k127_7101611_2	926569.ANT_03510	2.583e-76	261.0	COG0233@1|root,COG0233@2|Bacteria,2G6FY@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
WH1_k127_7101611_1	926569.ANT_03500	2.992e-90	318.0	COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
WH1_k127_7101611_4	926569.ANT_03490	7.082e-38	152.0	COG4589@1|root,COG4589@2|Bacteria,2G6QV@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
WH1_k127_7139629_0	1128421.JAGA01000002_gene1152	1.286e-34	155.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2NR6B@2323|unclassified Bacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH1_k127_7177882_1	5693.XP_811898.1	3.745e-67	235.0	COG0461@1|root,KOG1377@2759|Eukaryota,3XSWC@5653|Kinetoplastida	5653|Kinetoplastida	F	Orotidine-5-phosphate decarboxylase orotate phosphoribosyltransferase	-	-	2.4.2.10,4.1.1.23	ko:K01591,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
WH1_k127_7177882_0	1356852.N008_10810	4.913e-101	338.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,47KYQ@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
WH1_k127_7177885_1	1445613.JALM01000013_gene1948	7.264e-06	52.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4DXK5@85010|Pseudonocardiales	201174|Actinobacteria	M	glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
WH1_k127_7177885_0	926550.CLDAP_02080	5.003e-84	298.0	COG1216@1|root,COG1216@2|Bacteria,2G8PX@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_2
WH1_k127_7190725_0	1128421.JAGA01000003_gene2987	1.823e-13	77.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2NQG9@2323|unclassified Bacteria	2|Bacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12,Trans_reg_C
WH1_k127_7202500_1	682795.AciX8_4439	5.742e-17	80.0	COG0537@1|root,COG0537@2|Bacteria,3Y542@57723|Acidobacteria,2JJT8@204432|Acidobacteriia	204432|Acidobacteriia	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
WH1_k127_7202500_0	756499.Desde_3657	2.075e-28	123.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,24JB0@186801|Clostridia,261VR@186807|Peptococcaceae	186801|Clostridia	S	PFAM Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
WH1_k127_7202500_2	926569.ANT_14340	3.503e-11	70.0	COG1480@1|root,COG1480@2|Bacteria,2G5WC@200795|Chloroflexi	200795|Chloroflexi	S	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
WH1_k127_7210570_0	1303518.CCALI_00534	4.666e-46	168.0	COG0031@1|root,COG0031@2|Bacteria	2|Bacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113,2.5.1.47	ko:K12339,ko:K21148	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021	R00897,R03132,R03601,R04859,R10610	RC00020,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WH1_k127_7210570_1	1225785.CM001983_gene1886	3.001e-32	134.0	COG1310@1|root,COG1310@2|Bacteria,1QRZQ@1224|Proteobacteria,1S558@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	JAB1/Mov34/MPN/PAD-1 ubiquitin protease	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
WH1_k127_7210570_2	518766.Rmar_1679	3.228e-25	108.0	COG1977@1|root,COG1977@2|Bacteria,4NVU9@976|Bacteroidetes,1FJK9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
WH1_k127_7210570_3	926569.ANT_22750	6.321e-11	67.0	2DMUR@1|root,32TTD@2|Bacteria,2G72Z@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
WH1_k127_7212884_1	383372.Rcas_4163	3.941e-69	243.0	COG0846@1|root,COG0846@2|Bacteria,2G6QQ@200795|Chloroflexi,375GJ@32061|Chloroflexia	32061|Chloroflexia	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
WH1_k127_7212884_2	1172188.KB911822_gene707	2.92e-49	192.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
WH1_k127_7212884_0	1173028.ANKO01000116_gene5719	2.604e-76	264.0	COG2114@1|root,COG2114@2|Bacteria,1G6D6@1117|Cyanobacteria,1HB2S@1150|Oscillatoriales	1117|Cyanobacteria	T	COGs COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
WH1_k127_7212884_4	1128421.JAGA01000003_gene2909	1.276e-22	100.0	COG1225@1|root,COG1225@2|Bacteria,2NS47@2323|unclassified Bacteria	2|Bacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
WH1_k127_7212884_6	1229172.JQFA01000002_gene2947	0.000729	44.0	COG1225@1|root,COG1225@2|Bacteria,1G2SK@1117|Cyanobacteria,1H9D2@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM AhpC TSA family	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
WH1_k127_7212884_5	316274.Haur_4148	5.304e-10	61.0	COG3393@1|root,COG3393@2|Bacteria,2G8JB@200795|Chloroflexi	200795|Chloroflexi	S	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FR47
WH1_k127_7212884_3	926550.CLDAP_11130	5.076e-42	156.0	COG0165@1|root,COG0165@2|Bacteria,2G616@200795|Chloroflexi	200795|Chloroflexi	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
WH1_k127_7213987_0	926569.ANT_12370	2.365e-97	328.0	COG0624@1|root,COG0624@2|Bacteria,2G61X@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the release of L-lysine from LysW -gamma-L- lysine	lysK	-	-	ko:K05831	ko00220,ko00300,ko01100,ko01210,ko01230,map00220,map00300,map01100,map01210,map01230	M00031,M00763	R09779,R10933	RC00064,RC00090	ko00000,ko00001,ko00002	-	-	-	Peptidase_M20
WH1_k127_7213987_2	331678.Cphamn1_0814	6.377e-31	127.0	2E3B5@1|root,32YAP@2|Bacteria,1FE8N@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
WH1_k127_7213987_1	926569.ANT_16530	9.754e-50	185.0	COG2211@1|root,COG2211@2|Bacteria,2GA8Z@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH1_k127_7220453_2	195253.Syn6312_0565	0.0008754	49.0	COG1922@1|root,COG1922@2|Bacteria,1G9UY@1117|Cyanobacteria	1117|Cyanobacteria	M	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_7220453_1	316274.Haur_1125	3.397e-08	63.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_2,TPR_8
WH1_k127_7220453_0	309801.trd_0889	9.586e-38	145.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27YWR@189775|Thermomicrobia	189775|Thermomicrobia	E	NAD(P)-binding Rossmann-like domain	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
WH1_k127_7232172_0	926569.ANT_15140	1.882e-76	270.0	COG0484@1|root,COG2304@1|root,COG0484@2|Bacteria,COG2304@2|Bacteria,2G8H5@200795|Chloroflexi	200795|Chloroflexi	O	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
WH1_k127_7232172_2	926569.ANT_15130	2.769e-29	123.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
WH1_k127_7232172_3	926569.ANT_15120	6.699e-24	111.0	2EMHG@1|root,33F64@2|Bacteria,2G7IC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_7232172_1	926569.ANT_15110	5.86e-56	199.0	COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07667,ko:K07668	ko02020,ko02024,map02020,map02024	M00454,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WH1_k127_723785_0	1392489.JPOL01000001_gene3434	2.103e-09	70.0	COG3210@1|root,COG3210@2|Bacteria,4NGEX@976|Bacteroidetes,1HZV9@117743|Flavobacteriia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_7238106_0	1408438.JADD01000008_gene1487	1.123e-16	87.0	COG1388@1|root,COG1388@2|Bacteria,1UPFG@1239|Firmicutes,4IV66@91061|Bacilli	1239|Firmicutes	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
WH1_k127_7238106_1	1121865.OMW_01515	3.902e-07	61.0	COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,1UYRM@1239|Firmicutes,4HAU6@91061|Bacilli,4AZE2@81852|Enterococcaceae	91061|Bacilli	MNU	defense response to other organism	acmA	GO:0005575,GO:0005576	-	ko:K02395,ko:K19220,ko:K19223	-	-	-	-	ko00000,ko01000,ko01002,ko01011,ko02035	-	CBM50	-	Glucosaminidase,LysM
WH1_k127_7244845_0	485913.Krac_11734	2.896e-132	439.0	COG0488@1|root,COG0488@2|Bacteria	2|Bacteria	L	(ABC) transporter	yjjK	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WH1_k127_7244845_1	926550.CLDAP_07100	1.864e-101	336.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WH1_k127_7244845_4	485913.Krac_2843	2.09e-09	69.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WH1_k127_7244845_6	715226.ABI_14880	4.291e-05	52.0	COG1011@1|root,COG1011@2|Bacteria,1RA0T@1224|Proteobacteria	1224|Proteobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WH1_k127_7244845_3	497964.CfE428DRAFT_0440	5.478e-43	183.0	COG1361@1|root,COG1404@1|root,COG1520@1|root,COG3055@1|root,COG5184@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG1520@2|Bacteria,COG3055@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	DUF11,Kelch_4,SLH,SdrD_B
WH1_k127_7244845_5	370438.PTH_1102	8.814e-08	66.0	COG5434@1|root,COG5434@2|Bacteria,1UJS5@1239|Firmicutes,24VP2@186801|Clostridia,266SC@186807|Peptococcaceae	186801|Clostridia	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
WH1_k127_7244845_2	1499967.BAYZ01000090_gene4936	7.902e-44	185.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
WH1_k127_7254563_1	324602.Caur_2861	2.579e-69	244.0	COG0477@1|root,COG0477@2|Bacteria,2GA8H@200795|Chloroflexi,375E8@32061|Chloroflexia	32061|Chloroflexia	EGP	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WH1_k127_7254563_2	479434.Sthe_1683	3.521e-20	99.0	2DHVB@1|root,3012B@2|Bacteria,2GB5E@200795|Chloroflexi,27ZBK@189775|Thermomicrobia	189775|Thermomicrobia	S	LppX_LprAFG lipoprotein	-	-	-	ko:K14954	ko05152,map05152	-	-	-	ko00000,ko00001	-	-	-	LppX_LprAFG
WH1_k127_7254563_0	1128421.JAGA01000002_gene1395	1.134e-81	280.0	COG1453@1|root,COG1453@2|Bacteria	2|Bacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WH1_k127_7254563_3	760568.Desku_0139	0.0004775	50.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
WH1_k127_7277891_0	864051.BurJ1DRAFT_2685	8.635e-222	704.0	COG4117@1|root,COG4117@2|Bacteria,1R4HB@1224|Proteobacteria,2WFJG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
WH1_k127_7277891_1	864051.BurJ1DRAFT_2686	1.431e-68	238.0	COG2391@1|root,COG2391@2|Bacteria,1N3PQ@1224|Proteobacteria,2VXAQ@28216|Betaproteobacteria,1KP4P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WH1_k127_7277891_2	864051.BurJ1DRAFT_2687	3.341e-16	85.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,2VWMP@28216|Betaproteobacteria,1KNZM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WH1_k127_7278818_2	926550.CLDAP_10780	1.942e-18	95.0	COG1716@1|root,COG1716@2|Bacteria,2G8A1@200795|Chloroflexi	200795|Chloroflexi	T	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
WH1_k127_7278818_0	926550.CLDAP_10780	1.236e-219	709.0	COG1716@1|root,COG1716@2|Bacteria,2G8A1@200795|Chloroflexi	200795|Chloroflexi	T	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
WH1_k127_7278818_1	215803.DB30_3560	5.302e-33	132.0	COG2940@1|root,COG2940@2|Bacteria,1MWFB@1224|Proteobacteria,438IX@68525|delta/epsilon subdivisions,2X3TU@28221|Deltaproteobacteria,2YX3A@29|Myxococcales	28221|Deltaproteobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
WH1_k127_7297614_0	926569.ANT_13500	1.302e-79	275.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,2G6R8@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, MerR	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
WH1_k127_7297614_2	1303518.CCALI_00071	1.216e-10	69.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WH1_k127_7297614_1	926550.CLDAP_29030	3.4e-13	73.0	COG4276@1|root,COG4276@2|Bacteria,2G9EV@200795|Chloroflexi	200795|Chloroflexi	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_7298097_0	926550.CLDAP_21880	3.544e-42	169.0	COG3206@1|root,COG3206@2|Bacteria,2G9NW@200795|Chloroflexi	200795|Chloroflexi	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
WH1_k127_7335365_0	1313172.YM304_27660	2.176e-11	75.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
WH1_k127_7338977_1	926550.CLDAP_07480	1.797e-43	170.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WH1_k127_7338977_0	926569.ANT_20650	1.947e-111	372.0	COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi	200795|Chloroflexi	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
WH1_k127_7338977_2	1120950.KB892764_gene5624	1.376e-15	79.0	COG2197@1|root,COG2197@2|Bacteria,2GJKM@201174|Actinobacteria,4DQZM@85009|Propionibacteriales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH1_k127_7388832_0	926569.ANT_04530	0.0	1023.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi	200795|Chloroflexi	O	ATPase AAA-2 domain protein	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,HTH_17,UVR
WH1_k127_7408169_1	926550.CLDAP_39150	2.02e-16	83.0	COG3944@1|root,COG3944@2|Bacteria,2G7A7@200795|Chloroflexi	200795|Chloroflexi	M	Lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
WH1_k127_7408169_0	1382356.JQMP01000001_gene1021	1.024e-87	297.0	COG0438@1|root,COG0438@2|Bacteria,2G683@200795|Chloroflexi,27XEV@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH1_k127_7428691_3	429009.Adeg_2014	5.048e-62	220.0	COG1941@1|root,COG1941@2|Bacteria,1V21E@1239|Firmicutes,24GWD@186801|Clostridia,42HGR@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
WH1_k127_7428691_0	909663.KI867150_gene1871	1.062e-224	717.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,42N63@68525|delta/epsilon subdivisions,2WJPA@28221|Deltaproteobacteria,2MQRM@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM nickel-dependent hydrogenase, large subunit	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
WH1_k127_7428691_5	7245.FBpp0260894	0.0001095	50.0	2D82N@1|root,2T8G1@2759|Eukaryota,3930P@33154|Opisthokonta,3C8AX@33208|Metazoa,3DPBM@33213|Bilateria,425JT@6656|Arthropoda,3SV54@50557|Insecta,4587U@7147|Diptera,45Z7T@7214|Drosophilidae	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_7428691_4	1449126.JQKL01000002_gene1553	7.165e-22	105.0	COG0680@1|root,COG0680@2|Bacteria	2|Bacteria	C	spore germination	hybD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
WH1_k127_7428691_1	926569.ANT_17860	6.288e-120	406.0	COG0068@1|root,COG0068@2|Bacteria,2G5QN@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
WH1_k127_7428691_2	1463920.JOGB01000040_gene4130	5.33e-86	299.0	COG0068@1|root,COG0068@2|Bacteria,2GJYF@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
WH1_k127_7463585_1	926569.ANT_09240	1.45e-95	326.0	COG0534@1|root,COG0534@2|Bacteria	2|Bacteria	V	drug transmembrane transporter activity	norM	-	-	-	-	-	-	-	-	-	-	-	MatE
WH1_k127_7463585_0	765420.OSCT_2528	8.631e-143	464.0	COG0513@1|root,COG0513@2|Bacteria,2G5VR@200795|Chloroflexi,376J4@32061|Chloroflexia	200795|Chloroflexi	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
WH1_k127_7463585_2	404589.Anae109_0713	1.815e-05	49.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,2YZGM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
WH1_k127_7465723_1	926550.CLDAP_02910	6.476e-80	273.0	COG2270@1|root,COG2270@2|Bacteria,2G633@200795|Chloroflexi	200795|Chloroflexi	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
WH1_k127_7465723_0	926569.ANT_22580	5.069e-82	287.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,2G8F8@200795|Chloroflexi	200795|Chloroflexi	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
WH1_k127_7475086_0	1173026.Glo7428_3203	9.569e-56	198.0	COG4608@1|root,COG4608@2|Bacteria,1G1Q0@1117|Cyanobacteria	1117|Cyanobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WH1_k127_7475086_1	398767.Glov_0894	1.126e-10	69.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WKTU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH1_k127_7483019_0	338969.Rfer_0471	9.258e-122	395.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria,4ABQJ@80864|Comamonadaceae	28216|Betaproteobacteria	O	Mg chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WH1_k127_7483019_1	365046.Rta_01430	1.959e-28	118.0	2DQY9@1|root,339CR@2|Bacteria,1NR8Y@1224|Proteobacteria,2VSAP@28216|Betaproteobacteria,4AJC5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
WH1_k127_7500747_1	926569.ANT_02520	3.417e-64	229.0	COG0609@1|root,COG0609@2|Bacteria,2G6E8@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
WH1_k127_7500747_0	926569.ANT_02530	1.06e-81	285.0	COG0614@1|root,COG0614@2|Bacteria,2G6TS@200795|Chloroflexi	200795|Chloroflexi	P	periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
WH1_k127_7500747_3	926569.ANT_27460	5.505e-11	70.0	COG2919@1|root,COG2919@2|Bacteria,2G9Q3@200795|Chloroflexi	200795|Chloroflexi	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
WH1_k127_7500747_2	926569.ANT_08950	7.035e-15	83.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
WH1_k127_7514054_1	926569.ANT_07260	9.15e-27	113.0	COG4820@1|root,COG4820@2|Bacteria	2|Bacteria	E	ethanolamine catabolic process	eutJ	-	-	ko:K04024	-	-	-	-	ko00000	-	-	-	FtsA,HSP70,MreB_Mbl,PilM_2
WH1_k127_7514054_0	324602.Caur_1591	1.736e-74	269.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	ydeG	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WH1_k127_7514054_2	1458275.AZ34_13690	0.000376	50.0	COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2VKPZ@28216|Betaproteobacteria,4AB3E@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WH1_k127_7514698_0	102125.Xen7305DRAFT_00034880	5.473e-143	472.0	COG5421@1|root,COG5421@2|Bacteria,1G4EU@1117|Cyanobacteria,3VKV9@52604|Pleurocapsales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WH1_k127_7524353_1	1120949.KB903294_gene3937	4.534e-07	62.0	COG4675@1|root,COG4675@2|Bacteria	2|Bacteria	M	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF859,Laminin_G_3
WH1_k127_7524353_0	357808.RoseRS_1668	1.308e-131	441.0	COG2518@1|root,COG4797@1|root,COG2518@2|Bacteria,COG4797@2|Bacteria	2|Bacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259	2.1.1.163,2.1.1.201,2.1.1.77	ko:K00573,ko:K03183,ko:K07003	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3560,MethyTransf_Reg,Methyltransf_12,Methyltransf_25,Methyltransf_31
WH1_k127_7531853_2	926550.CLDAP_39150	3.218e-32	134.0	COG3944@1|root,COG3944@2|Bacteria,2G7A7@200795|Chloroflexi	200795|Chloroflexi	M	Lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
WH1_k127_7531853_0	926550.CLDAP_39140	2.692e-125	412.0	COG0438@1|root,COG0438@2|Bacteria,2G683@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH1_k127_7531853_1	1128421.JAGA01000002_gene1699	3.729e-51	188.0	COG0164@1|root,COG0164@2|Bacteria,2NPD1@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
WH1_k127_7535879_1	926550.CLDAP_07270	2.087e-43	162.0	2DT85@1|root,33J4K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_7535879_0	1128421.JAGA01000002_gene1308	5.853e-64	229.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH1_k127_7535879_3	255470.cbdbA646	8.498e-39	164.0	COG4585@1|root,COG4585@2|Bacteria,2G8PE@200795|Chloroflexi,34CQA@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
WH1_k127_7535879_6	877455.Metbo_0010	1.871e-14	77.0	COG3350@1|root,arCOG04507@2157|Archaea,2Y15C@28890|Euryarchaeota	28890|Euryarchaeota	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
WH1_k127_7535879_2	926550.CLDAP_14450	2.262e-42	172.0	COG3815@1|root,COG3815@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
WH1_k127_7535879_5	644966.Tmar_1592	3.307e-24	115.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069,Lactamase_B,Rhodanese
WH1_k127_7535879_4	479434.Sthe_0358	2.407e-26	115.0	2E3IJ@1|root,32YH0@2|Bacteria,2G7AM@200795|Chloroflexi,27Z7F@189775|Thermomicrobia	189775|Thermomicrobia	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
WH1_k127_7551461_1	383372.Rcas_1839	1.095e-30	124.0	COG0438@1|root,COG0438@2|Bacteria,2G7TE@200795|Chloroflexi,3750Z@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	2.4.1.348	ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
WH1_k127_7551461_0	926550.CLDAP_10360	5.793e-120	400.0	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria,2G81B@200795|Chloroflexi	200795|Chloroflexi	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,Wzy_C
WH1_k127_7569174_0	926550.CLDAP_18560	5.332e-154	491.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
WH1_k127_7591578_0	263358.VAB18032_02245	6.888e-155	502.0	COG1404@1|root,COG1404@2|Bacteria,2I8MD@201174|Actinobacteria,4DBMJ@85008|Micromonosporales	201174|Actinobacteria	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,SLH
WH1_k127_7591578_1	867845.KI911784_gene1357	6.578e-36	140.0	COG1071@1|root,COG1071@2|Bacteria,2G6HY@200795|Chloroflexi,3754C@32061|Chloroflexia	32061|Chloroflexia	C	PFAM dehydrogenase, E1 component	-	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
WH1_k127_7593613_2	398767.Glov_2398	6.826e-44	166.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42R04@68525|delta/epsilon subdivisions,2WMZ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM ATPase, BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
WH1_k127_7593613_1	76114.ebA5296	2.812e-60	217.0	COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,2VUI3@28216|Betaproteobacteria,2KWVM@206389|Rhodocyclales	206389|Rhodocyclales	I	Enoyl-CoA hydratase/isomerase	dch	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WH1_k127_7593613_0	1379698.RBG1_1C00001G0892	8.524e-95	318.0	COG1062@1|root,COG1062@2|Bacteria	2|Bacteria	C	S-(hydroxymethyl)glutathione dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N
WH1_k127_760246_0	926569.ANT_03460	5.958e-221	700.0	COG1164@1|root,COG1164@2|Bacteria,2G5JB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
WH1_k127_760246_1	926569.ANT_24700	2.595e-66	229.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi	200795|Chloroflexi	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
WH1_k127_7614509_0	765420.OSCT_0268	2.127e-78	268.0	COG0313@1|root,COG0313@2|Bacteria,2G6E3@200795|Chloroflexi,375JE@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
WH1_k127_7614509_1	926569.ANT_26490	4.685e-37	152.0	COG0760@1|root,COG0760@2|Bacteria,2G9A4@200795|Chloroflexi	200795|Chloroflexi	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
WH1_k127_7614509_2	324602.Caur_0989	4.797e-24	105.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi,374ZT@32061|Chloroflexia	32061|Chloroflexia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
WH1_k127_7616033_0	526227.Mesil_0789	4.531e-80	274.0	COG1131@1|root,COG1131@2|Bacteria,1WJ0H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH1_k127_7616033_2	357808.RoseRS_3279	8.545e-67	245.0	COG1277@1|root,COG1277@2|Bacteria,2G79P@200795|Chloroflexi	200795|Chloroflexi	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
WH1_k127_7616033_4	1115632.JAFW01000001_gene1286	0.0006506	52.0	COG0642@1|root,COG0642@2|Bacteria,2I58H@201174|Actinobacteria	201174|Actinobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
WH1_k127_7616033_1	477974.Daud_1846	2.234e-78	277.0	COG2199@1|root,COG3706@2|Bacteria,1TSW8@1239|Firmicutes,249J7@186801|Clostridia,261UM@186807|Peptococcaceae	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	GGDEF,PAS_9,Response_reg
WH1_k127_7616033_3	448385.sce7696	1.992e-61	228.0	COG1404@1|root,COG1404@2|Bacteria,1PEJJ@1224|Proteobacteria,438RE@68525|delta/epsilon subdivisions,2X3YD@28221|Deltaproteobacteria,2YXKA@29|Myxococcales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WH1_k127_7629114_0	1125863.JAFN01000001_gene1552	2.218e-216	686.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	2|Bacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_4,Fer4_7,NAD_binding_8,Pyr_redox_2
WH1_k127_7629114_3	429009.Adeg_0343	3.774e-44	183.0	COG1908@1|root,COG1908@2|Bacteria,1V638@1239|Firmicutes,24J0E@186801|Clostridia,42IDY@68295|Thermoanaerobacterales	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
WH1_k127_7629114_2	1125863.JAFN01000001_gene1549	4.825e-88	295.0	COG4656@1|root,COG4656@2|Bacteria,1MWAX@1224|Proteobacteria,42NJM@68525|delta/epsilon subdivisions,2WJJB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
WH1_k127_7629114_1	1125863.JAFN01000001_gene1548	9.197e-136	442.0	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
WH1_k127_7646049_1	402777.KB235898_gene5022	2.808e-52	198.0	COG3409@1|root,COG3757@1|root,COG3409@2|Bacteria,COG3757@2|Bacteria,1G3TT@1117|Cyanobacteria,1H8M4@1150|Oscillatoriales	1117|Cyanobacteria	M	SMART Glycoside hydrolase, family 25 subgroup	-	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25,PG_binding_1
WH1_k127_7646049_0	926550.CLDAP_36010	1.592e-67	243.0	COG3103@1|root,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	-	-	3.5.1.28	ko:K01448,ko:K07448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko02048,ko03036	-	-	-	Muraidase,SH3_3,SLH
WH1_k127_7646049_2	1121935.AQXX01000123_gene248	1.64e-51	190.0	COG3103@1|root,COG3103@2|Bacteria,1R8YR@1224|Proteobacteria,1S0Q4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Pfam:DUF3380	-	-	-	-	-	-	-	-	-	-	-	-	Muraidase,SH3_3
WH1_k127_7650078_2	1121422.AUMW01000002_gene2260	0.0001799	49.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia,26015@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
WH1_k127_7650078_0	926569.ANT_11390	4.39e-125	406.0	COG0005@1|root,COG0005@2|Bacteria,2G5JP@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
WH1_k127_7650078_1	867845.KI911784_gene1882	1.04e-19	94.0	COG1716@1|root,COG1716@2|Bacteria,2G759@200795|Chloroflexi,375UJ@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
WH1_k127_7670442_0	1210884.HG799466_gene12656	9.686e-65	230.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	2.1.1.242,2.1.1.303,2.1.1.319	ko:K11434,ko:K15984,ko:K20421	ko01059,ko01130,ko04068,ko04922,map01059,map01130,map04068,map04922	M00830	R10963,R11216,R11217,R11219	RC00003,RC00392,RC02120,RC03388,RC03390	ko00000,ko00001,ko00002,ko01000,ko03009,ko03036	-	-	-	DOT1,Methyltransf_21,Methyltransf_25
WH1_k127_7672367_1	383372.Rcas_0802	3.734e-41	158.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi,375HS@32061|Chloroflexia	32061|Chloroflexia	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
WH1_k127_7672367_2	867845.KI911784_gene600	1.849e-29	126.0	COG1556@1|root,COG1556@2|Bacteria,2G7BK@200795|Chloroflexi,37778@32061|Chloroflexia	32061|Chloroflexia	S	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
WH1_k127_7672367_0	1521187.JPIM01000077_gene1101	7.508e-144	471.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,2G665@200795|Chloroflexi,37659@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM iron-sulfur cluster binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_7,Fer4_8,LUD_dom
WH1_k127_7682806_0	926569.ANT_09360	1.108e-194	619.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi	200795|Chloroflexi	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
WH1_k127_7682806_1	1223545.GS4_35_00640	2.16e-132	430.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4GBQE@85026|Gordoniaceae	201174|Actinobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
WH1_k127_7682806_2	1125718.HMPREF1318_2611	1.11e-23	103.0	COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria,4D37N@85005|Actinomycetales	201174|Actinobacteria	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
WH1_k127_7706579_0	383372.Rcas_1439	8.054e-35	150.0	COG1928@1|root,COG1928@2|Bacteria,2G8YA@200795|Chloroflexi,375IA@32061|Chloroflexia	32061|Chloroflexia	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_7708084_0	926550.CLDAP_37400	1.795e-120	398.0	COG0577@1|root,COG0577@2|Bacteria,2G6IW@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH1_k127_7708084_1	316274.Haur_1468	4.045e-81	276.0	COG1136@1|root,COG1136@2|Bacteria,2G8HT@200795|Chloroflexi,375FM@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH1_k127_7708084_2	794903.OPIT5_25520	0.0005741	52.0	COG4254@1|root,COG4254@2|Bacteria,46XWE@74201|Verrucomicrobia,3K8GN@414999|Opitutae	414999|Opitutae	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
WH1_k127_7711685_1	537013.CLOSTMETH_01139	2.565e-07	58.0	COG0347@1|root,COG0347@2|Bacteria,1UJDU@1239|Firmicutes	1239|Firmicutes	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_7711685_0	316274.Haur_3439	1.704e-110	370.0	COG0475@1|root,COG0475@2|Bacteria,2G6B0@200795|Chloroflexi,375SB@32061|Chloroflexia	32061|Chloroflexia	P	PFAM sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
WH1_k127_7737444_1	1089550.ATTH01000001_gene2414	2.479e-92	324.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,1FJQP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyl transferase family 21	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3
WH1_k127_7737444_0	926569.ANT_23640	1.114e-151	497.0	COG2114@1|root,COG2203@1|root,COG5002@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2G6X8@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,GAF_3,Guanylate_cyc,PAS
WH1_k127_7752795_1	1173024.KI912151_gene1817	8.743e-46	170.0	COG0221@1|root,COG0221@2|Bacteria,1GKG1@1117|Cyanobacteria,1JM4R@1189|Stigonemataceae	1117|Cyanobacteria	C	Inorganic pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Pyrophosphatase
WH1_k127_7752795_0	926569.ANT_15750	1.383e-96	329.0	COG0635@1|root,COG0635@2|Bacteria,2G5NK@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
WH1_k127_7755190_0	1131730.BAVI_16832	3.493e-154	502.0	COG0644@1|root,COG0644@2|Bacteria,1TR0D@1239|Firmicutes,4HBWH@91061|Bacilli,1ZDCV@1386|Bacillus	91061|Bacilli	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
WH1_k127_7764980_1	926569.ANT_29560	2.153e-25	120.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	CP_0034	-	-	-	-	-	-	-	-	-	-	-	BON,FHA,FTSW_RODA_SPOVE,Yop-YscD_cpl
WH1_k127_7764980_2	1248760.ANFZ01000018_gene518	3.312e-13	75.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2K20D@204457|Sphingomonadales	204457|Sphingomonadales	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
WH1_k127_7764980_0	582744.Msip34_1226	3.55e-33	135.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria,2KKEQ@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
WH1_k127_7778490_0	243164.DET1196	8.813e-204	658.0	COG0210@1|root,COG0210@2|Bacteria,2G5XF@200795|Chloroflexi,34D7Z@301297|Dehalococcoidia	301297|Dehalococcoidia	L	UvrD/REP helicase N-terminal domain	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WH1_k127_7778490_2	246969.TAM4_1780	1.209e-08	64.0	COG2306@1|root,arCOG05760@2157|Archaea,2XX0W@28890|Euryarchaeota,243ZF@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF402)	-	-	-	ko:K09145	-	-	-	-	ko00000	-	-	-	DUF402
WH1_k127_7778490_1	240015.ACP_3478	7.941e-113	372.0	COG1087@1|root,COG1087@2|Bacteria,3Y3FK@57723|Acidobacteria,2JI2G@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WH1_k127_7778490_3	1236501.BAJU01000011_gene1493	1.92e-07	63.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,2TR01@28211|Alphaproteobacteria,2JQKE@204441|Rhodospirillales	204441|Rhodospirillales	O	Molecular chaperone	cbpA	-	-	-	-	-	-	-	-	-	-	-	DnaJ,DnaJ_C
WH1_k127_7780108_1	926554.KI912620_gene1119	6.75e-38	149.0	COG3694@1|root,COG3694@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WH1_k127_7780108_0	1121377.KB906398_gene2455	1.04e-73	257.0	COG4587@1|root,COG4587@2|Bacteria	2|Bacteria	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WH1_k127_7780108_2	357808.RoseRS_2829	1.687e-23	109.0	COG1404@1|root,COG1404@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Peptidase_S8
WH1_k127_7805283_0	926569.ANT_09210	6.789e-110	366.0	COG0745@1|root,COG2114@1|root,COG5000@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP,dCache_1,dCache_3
WH1_k127_7807208_2	926550.CLDAP_01220	1.561e-21	99.0	COG3944@1|root,COG3944@2|Bacteria,2G9GX@200795|Chloroflexi	200795|Chloroflexi	M	PFAM lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
WH1_k127_7807208_1	926550.CLDAP_39150	8.618e-35	142.0	COG3944@1|root,COG3944@2|Bacteria,2G7A7@200795|Chloroflexi	200795|Chloroflexi	M	Lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
WH1_k127_7807208_0	926550.CLDAP_39140	8.277e-75	258.0	COG0438@1|root,COG0438@2|Bacteria,2G683@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH1_k127_7816789_1	926569.ANT_18000	1.14e-08	57.0	COG2151@1|root,COG2151@2|Bacteria,2G9UF@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
WH1_k127_7816789_0	479434.Sthe_2607	6.815e-159	513.0	COG1032@1|root,COG1032@2|Bacteria,2G7MA@200795|Chloroflexi,27Y05@189775|Thermomicrobia	189775|Thermomicrobia	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
WH1_k127_7829540_2	593750.Metfor_2256	1.49e-20	95.0	COG1366@1|root,arCOG06891@2157|Archaea,2Y5F7@28890|Euryarchaeota	28890|Euryarchaeota	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
WH1_k127_7829540_1	1128421.JAGA01000001_gene2037	3.954e-28	118.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2NRQE@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS,STAS_2
WH1_k127_7829540_0	926569.ANT_05800	3.205e-119	391.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WH1_k127_7840934_7	1122915.AUGY01000102_gene4728	5.309e-13	81.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,26QWH@186822|Paenibacillaceae	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,LytTR,PAS,PAS_3,PAS_9,Peripla_BP_3,Response_reg
WH1_k127_7840934_5	335543.Sfum_3567	4.807e-40	166.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria,2MSID@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
WH1_k127_7840934_2	926550.CLDAP_01880	1.45e-122	403.0	COG3664@1|root,COG3664@2|Bacteria,2G82D@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_7840934_6	326427.Cagg_0513	1.663e-22	107.0	COG0834@1|root,COG0834@2|Bacteria,2G8WT@200795|Chloroflexi,375S2@32061|Chloroflexia	32061|Chloroflexia	ET	extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
WH1_k127_7840934_8	926569.ANT_30350	1.939e-05	57.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_30350|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_7840934_0	500637.PROVRUST_05668	3.753e-222	721.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,3Z7RA@586|Providencia	1236|Gammaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WH1_k127_7840934_4	105559.Nwat_2927	7.374e-71	251.0	COG4823@1|root,COG4823@2|Bacteria,1NJIX@1224|Proteobacteria,1RSPZ@1236|Gammaproteobacteria,1X0TA@135613|Chromatiales	135613|Chromatiales	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
WH1_k127_7840934_1	926569.ANT_30330	1.054e-133	454.0	COG0457@1|root,COG0457@2|Bacteria,2G73P@200795|Chloroflexi	200795|Chloroflexi	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
WH1_k127_7840934_3	926569.ANT_09470	4.94e-89	302.0	COG1624@1|root,COG1624@2|Bacteria,2G6J7@200795|Chloroflexi	200795|Chloroflexi	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
WH1_k127_7848734_1	926569.ANT_19800	6.486e-154	501.0	COG0210@1|root,COG0210@2|Bacteria,2G7VU@200795|Chloroflexi	200795|Chloroflexi	F	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_7848734_0	926569.ANT_19790	6.491e-219	704.0	COG0210@1|root,COG0210@2|Bacteria,2G86J@200795|Chloroflexi	200795|Chloroflexi	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WH1_k127_7848734_2	926569.ANT_19780	6.658e-06	50.0	COG2887@1|root,COG2887@2|Bacteria,2G8SQ@200795|Chloroflexi	200795|Chloroflexi	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
WH1_k127_7855045_0	383372.Rcas_1231	1.401e-77	263.0	COG3458@1|root,COG3458@2|Bacteria,2G5R9@200795|Chloroflexi,376UE@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM Acetyl xylan esterase	-	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
WH1_k127_7855045_1	448385.sce6677	4.963e-43	164.0	COG0738@1|root,COG0738@2|Bacteria	2|Bacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH1_k127_785538_0	56110.Oscil6304_4147	1.921e-48	190.0	COG1305@1|root,COG1305@2|Bacteria,1FZW2@1117|Cyanobacteria,1H7X1@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Transglutaminase-like superfamily	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
WH1_k127_7861636_0	246194.CHY_1224	2.939e-125	419.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,42F3G@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
WH1_k127_7862761_1	321327.CYA_2362	7.638e-21	104.0	COG0601@1|root,COG0601@2|Bacteria,1G23K@1117|Cyanobacteria,1H47A@1129|Synechococcus	1117|Cyanobacteria	P	ABC-type dipeptide oligopeptide nickel transport	-	-	2.4.2.7	ko:K00759,ko:K02033	ko00230,ko01100,ko02024,map00230,map01100,map02024	M00239	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko00002,ko01000,ko02000,ko04147	3.A.1.5	-	-	BPD_transp_1
WH1_k127_7862761_0	316274.Haur_4601	9.991e-46	181.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	MA20_13270	-	-	ko:K02034,ko:K13891,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00348,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.11,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
WH1_k127_7864962_0	278957.ABEA03000080_gene3201	7.239e-89	303.0	COG3547@1|root,COG3547@2|Bacteria,46SUI@74201|Verrucomicrobia,3K9PW@414999|Opitutae	414999|Opitutae	L	transposase IS116 IS110 IS902 family protein	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
WH1_k127_7912997_0	1394178.AWOO02000002_gene1841	8.171e-146	481.0	COG3333@1|root,COG3333@2|Bacteria,2GJB2@201174|Actinobacteria,4EI7P@85012|Streptosporangiales	201174|Actinobacteria	S	PFAM Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
WH1_k127_7934704_1	926569.ANT_00170	1.738e-69	241.0	COG0177@1|root,COG0177@2|Bacteria,2G6QA@200795|Chloroflexi	200795|Chloroflexi	L	FES	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
WH1_k127_7934704_0	1128421.JAGA01000002_gene163	3.686e-120	398.0	COG1063@1|root,COG1063@2|Bacteria,2NPK3@2323|unclassified Bacteria	2|Bacteria	E	Zinc-binding dehydrogenase	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
WH1_k127_7934704_2	1382306.JNIM01000001_gene847	1.002e-10	72.0	COG0515@1|root,COG0515@2|Bacteria	1382306.JNIM01000001_gene847|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_795683_0	1449126.JQKL01000004_gene620	3.612e-136	451.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,2689E@186813|unclassified Clostridiales	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
WH1_k127_795683_1	309801.trd_0578	2.028e-78	266.0	COG2080@1|root,COG2080@2|Bacteria,2GBQV@200795|Chloroflexi,27Y9S@189775|Thermomicrobia	189775|Thermomicrobia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
WH1_k127_795683_2	1123072.AUDH01000027_gene1856	1.589e-14	76.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	carbon monoxide dehydrogenase	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
WH1_k127_7960279_0	926550.CLDAP_23150	1.691e-67	242.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WH1_k127_7964826_1	324602.Caur_3056	4.459e-24	107.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH1_k127_7964826_0	324602.Caur_3056	3.897e-58	210.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH1_k127_7979591_0	368408.Tpen_0832	4.324e-96	327.0	COG0330@1|root,arCOG01915@2157|Archaea,2XPQN@28889|Crenarchaeota	28889|Crenarchaeota	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WH1_k127_7979591_1	1123376.AUIU01000012_gene1446	2.56e-87	308.0	COG1030@1|root,COG1030@2|Bacteria,3J0WF@40117|Nitrospirae	40117|Nitrospirae	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
WH1_k127_7979591_10	383372.Rcas_4227	4.053e-12	68.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi,376HK@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH1_k127_7979591_6	383372.Rcas_4228	1.222e-34	139.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,Response_reg
WH1_k127_7979591_5	1210908.HSB1_09510	2.127e-40	166.0	COG3358@1|root,arCOG04570@2157|Archaea,2XX3J@28890|Euryarchaeota,23VM5@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
WH1_k127_7979591_4	926569.ANT_31550	1.882e-44	182.0	COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi	200795|Chloroflexi	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
WH1_k127_7979591_2	926569.ANT_30100	1.807e-77	282.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Lactamase_B,Lactamase_B_2,cNMP_binding
WH1_k127_7979591_3	485913.Krac_10314	1.52e-64	235.0	COG1718@1|root,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	IV02_22125	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
WH1_k127_7979591_12	1499967.BAYZ01000188_gene3886	2.726e-05	49.0	COG0553@1|root,COG3886@1|root,COG0553@2|Bacteria,COG3886@2|Bacteria,2NQHS@2323|unclassified Bacteria	2|Bacteria	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII,SNF2_N
WH1_k127_7979591_8	1122962.AULH01000004_gene2360	3.711e-27	119.0	COG0664@1|root,COG0664@2|Bacteria,1NPY0@1224|Proteobacteria,2TT13@28211|Alphaproteobacteria,371AU@31993|Methylocystaceae	28211|Alphaproteobacteria	T	helix_turn_helix, cAMP Regulatory protein	nnrR	-	-	ko:K21564	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WH1_k127_7979591_7	926550.CLDAP_07210	2.217e-31	127.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	cycA	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	Cytochrom_C,Cytochrome_CBB3
WH1_k127_7979667_1	309801.trd_0521	1.925e-80	279.0	COG1177@1|root,COG1177@2|Bacteria,2G6DH@200795|Chloroflexi,27Y3I@189775|Thermomicrobia	189775|Thermomicrobia	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
WH1_k127_7979667_0	479434.Sthe_1279	1.86e-114	384.0	COG0687@1|root,COG0687@2|Bacteria,2G6U4@200795|Chloroflexi,27XZQ@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
WH1_k127_7979667_3	1380390.JIAT01000009_gene799	7.687e-67	235.0	COG3467@1|root,COG3467@2|Bacteria,2GJ76@201174|Actinobacteria,4CRWG@84995|Rubrobacteria	84995|Rubrobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
WH1_k127_7979667_2	357808.RoseRS_4538	1.595e-73	254.0	COG0667@1|root,COG0667@2|Bacteria,2G5V3@200795|Chloroflexi,377XZ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WH1_k127_802774_1	357808.RoseRS_1890	7.973e-25	107.0	COG2304@1|root,COG2304@2|Bacteria,2GABP@200795|Chloroflexi,37510@32061|Chloroflexia	32061|Chloroflexia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
WH1_k127_802774_0	1128421.JAGA01000003_gene3249	6.053e-74	258.0	COG1721@1|root,COG1721@2|Bacteria,2NP6B@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WH1_k127_802774_2	1303518.CCALI_00831	5.198e-14	73.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WH1_k127_8029802_0	33876.JNXY01000006_gene1028	3.249e-05	57.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria,4DM47@85008|Micromonosporales	201174|Actinobacteria	U	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8041092_0	1521187.JPIM01000229_gene2475	8.209e-41	161.0	COG5421@1|root,COG5421@2|Bacteria,2G7SD@200795|Chloroflexi,376XS@32061|Chloroflexia	32061|Chloroflexia	L	COGs COG5421 Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8042761_1	1384054.N790_14835	1.391e-114	370.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1X497@135614|Xanthomonadales	135614|Xanthomonadales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
WH1_k127_8042761_0	1384054.N790_14830	3.85e-238	741.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1X3DW@135614|Xanthomonadales	135614|Xanthomonadales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
WH1_k127_8042761_2	1384054.N790_14825	1.084e-80	284.0	COG0810@1|root,COG0810@2|Bacteria,1NH16@1224|Proteobacteria,1TDHV@1236|Gammaproteobacteria,1XAT0@135614|Xanthomonadales	135614|Xanthomonadales	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_804367_0	1128421.JAGA01000002_gene1417	5.199e-62	218.0	COG2178@1|root,COG2178@2|Bacteria,2NR1U@2323|unclassified Bacteria	2|Bacteria	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
WH1_k127_804367_3	1128421.JAGA01000003_gene3288	2.713e-08	57.0	2EI16@1|root,33BSP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_804367_1	1128421.JAGA01000003_gene3289	1.294e-38	152.0	COG1468@1|root,COG1468@2|Bacteria	2|Bacteria	L	DNA catabolic process, exonucleolytic	-	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4,DUF2779,PDDEXK_1
WH1_k127_804367_2	926569.ANT_00510	2.988e-20	95.0	COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
WH1_k127_8054982_0	926550.CLDAP_30390	1.511e-63	236.0	COG5427@1|root,COG5427@2|Bacteria,2G6AA@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
WH1_k127_805840_0	1125863.JAFN01000001_gene1552	6.414e-203	645.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	2|Bacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_4,Fer4_7,NAD_binding_8,Pyr_redox_2
WH1_k127_805840_1	264732.Moth_1193	1.859e-47	177.0	COG1908@1|root,COG1908@2|Bacteria,1V638@1239|Firmicutes,24J0E@186801|Clostridia,42IDY@68295|Thermoanaerobacterales	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
WH1_k127_805840_2	1125863.JAFN01000001_gene1552	7.779e-12	66.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	2|Bacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_4,Fer4_7,NAD_binding_8,Pyr_redox_2
WH1_k127_8059139_0	926550.CLDAP_11790	3.137e-97	333.0	COG2244@1|root,COG4485@1|root,COG2244@2|Bacteria,COG4485@2|Bacteria,2G6CM@200795|Chloroflexi	200795|Chloroflexi	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
WH1_k127_8077680_1	682795.AciX8_0137	1.214e-62	229.0	COG0697@1|root,COG0697@2|Bacteria,3Y4NT@57723|Acidobacteria,2JJ8M@204432|Acidobacteriia	204432|Acidobacteriia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WH1_k127_8077680_2	45351.EDO47632	1.116e-11	78.0	KOG4351@1|root,KOG4351@2759|Eukaryota,38HHX@33154|Opisthokonta,3B9X5@33208|Metazoa	33208|Metazoa	S	ubiquitin binding	C6orf106	GO:0000407,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005776,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016236,GO:0032182,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0061919	-	-	-	-	-	-	-	-	-	-	N_BRCA1_IG,UBA_4
WH1_k127_8077680_0	926550.CLDAP_34880	7.752e-64	239.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	MA20_15015	-	-	-	-	-	-	-	-	-	-	-	DUF1236,SH3_3
WH1_k127_8079291_0	1128421.JAGA01000002_gene1307	1.469e-42	177.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA_3,PAS,PAS_4,PAS_8
WH1_k127_8079291_1	1128421.JAGA01000002_gene1308	4.057e-31	125.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH1_k127_8111339_5	264732.Moth_0570	1.42e-18	94.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,42GEY@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM competence protein ComEA helix-hairpin-helix	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
WH1_k127_8111339_0	926569.ANT_11270	3.364e-82	282.0	COG1811@1|root,COG1811@2|Bacteria,2G6S2@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
WH1_k127_8111339_1	926569.ANT_14980	2.437e-67	243.0	COG3268@1|root,COG3268@2|Bacteria,2G93K@200795|Chloroflexi	200795|Chloroflexi	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
WH1_k127_8111339_3	926569.ANT_03770	1.107e-20	100.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi	200795|Chloroflexi	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
WH1_k127_8111339_2	926569.ANT_13840	2.329e-48	184.0	COG0454@1|root,COG0456@2|Bacteria,2G7CX@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WH1_k127_8111339_4	926569.ANT_01520	1.362e-18	88.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi	200795|Chloroflexi	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
WH1_k127_8120487_1	194439.CT0795	5.802e-06	53.0	COG1030@1|root,COG1030@2|Bacteria,1FEQ2@1090|Chlorobi	1090|Chlorobi	O	PFAM peptidase S14 ClpP	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
WH1_k127_8120487_0	926569.ANT_29010	3.84e-125	409.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	200795|Chloroflexi	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WH1_k127_8123007_0	991905.SL003B_1325	1.497e-05	57.0	COG5305@1|root,COG5305@2|Bacteria,1R9UF@1224|Proteobacteria	1224|Proteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WH1_k127_8127773_1	1121920.AUAU01000021_gene2530	4.303e-23	111.0	COG0823@1|root,COG0823@2|Bacteria,3Y2RC@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
WH1_k127_8127773_0	926550.CLDAP_35810	1.67e-64	232.0	COG3359@1|root,COG3359@2|Bacteria	2|Bacteria	L	RNase_H superfamily	yprB	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
WH1_k127_8132079_0	926569.ANT_25290	5.068e-115	391.0	COG0653@1|root,COG0653@2|Bacteria,2G603@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WH1_k127_814096_2	1124780.ANNU01000021_gene3017	5.93e-69	237.0	COG3396@1|root,COG3396@2|Bacteria,4NFJN@976|Bacteroidetes,47TVD@768503|Cytophagia	976|Bacteroidetes	S	Phenylacetic acid catabolic protein	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
WH1_k127_814096_1	926569.ANT_13170	4.671e-72	254.0	COG4758@1|root,COG4758@2|Bacteria,2G93M@200795|Chloroflexi	200795|Chloroflexi	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_814096_0	926569.ANT_25960	2.293e-152	488.0	COG0320@1|root,COG0320@2|Bacteria,2G5MH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
WH1_k127_814096_3	316274.Haur_0454	1.403e-50	190.0	COG0321@1|root,COG0321@2|Bacteria,2G8KT@200795|Chloroflexi,375KR@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
WH1_k127_814096_4	293826.Amet_3545	2.068e-11	67.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,36FRF@31979|Clostridiaceae	186801|Clostridia	E	Histidinol phosphate phosphatase, HisJ family	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
WH1_k127_8166529_0	926550.CLDAP_12670	3.941e-88	302.0	COG3307@1|root,COG3307@2|Bacteria,2G6B1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WH1_k127_8187077_1	1165096.ARWF01000001_gene1946	2.39e-11	74.0	2EKS4@1|root,33EFW@2|Bacteria,1NNJB@1224|Proteobacteria,2VYYD@28216|Betaproteobacteria,2KN2B@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
WH1_k127_8187077_0	290398.Csal_2594	9.188e-26	118.0	COG1651@1|root,COG1651@2|Bacteria,1NEFD@1224|Proteobacteria,1RQAW@1236|Gammaproteobacteria,1XMWA@135619|Oceanospirillales	135619|Oceanospirillales	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbG	-	-	ko:K03805	-	-	-	-	ko00000,ko03110	-	-	-	Thioredoxin_2
WH1_k127_8196921_0	635013.TherJR_0027	9.118e-61	216.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,261KZ@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
WH1_k127_8196921_1	485913.Krac_9833	3.664e-19	89.0	COG1080@1|root,COG1080@2|Bacteria,2G806@200795|Chloroflexi	200795|Chloroflexi	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
WH1_k127_8199461_0	215803.DB30_8813	8.035e-06	57.0	COG3409@1|root,COG3409@2|Bacteria,1N9AN@1224|Proteobacteria,42XYC@68525|delta/epsilon subdivisions,2WSN6@28221|Deltaproteobacteria,2YZQ1@29|Myxococcales	28221|Deltaproteobacteria	M	Putative peptidoglycan binding domain	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,VanY
WH1_k127_8209117_0	357808.RoseRS_4452	2.375e-33	146.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi,374TJ@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS
WH1_k127_8217544_0	326427.Cagg_1751	2.506e-76	267.0	COG0444@1|root,COG4608@1|root,COG0444@2|Bacteria,COG4608@2|Bacteria,2GBKB@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
WH1_k127_8217544_1	324602.Caur_1365	2.318e-15	80.0	COG0601@1|root,COG0601@2|Bacteria,2G8K4@200795|Chloroflexi	200795|Chloroflexi	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WH1_k127_8218889_0	1128421.JAGA01000002_gene867	1.454e-42	170.0	COG1316@1|root,COG1316@2|Bacteria,2NR49@2323|unclassified Bacteria	2|Bacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
WH1_k127_8222517_1	926569.ANT_16790	7.694e-98	325.0	COG0403@1|root,COG0403@2|Bacteria,2G5NI@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
WH1_k127_8222517_0	926569.ANT_16800	2.092e-228	716.0	COG1003@1|root,COG1003@2|Bacteria,2G5MU@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
WH1_k127_8222517_2	1294143.H681_01230	3.242e-36	143.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	VP0394	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
WH1_k127_8225640_1	644282.Deba_2986	1.429e-63	225.0	COG0095@1|root,COG0095@2|Bacteria,1RDZE@1224|Proteobacteria	1224|Proteobacteria	H	PFAM biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
WH1_k127_8225640_2	525909.Afer_0973	8.589e-33	132.0	COG0509@1|root,COG0509@2|Bacteria,2HGPW@201174|Actinobacteria,4CNSC@84992|Acidimicrobiia	84992|Acidimicrobiia	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	-	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
WH1_k127_8225640_0	1123288.SOV_7c00310	2.367e-88	302.0	COG0247@1|root,COG0247@2|Bacteria,1TPG1@1239|Firmicutes,4H3AP@909932|Negativicutes	909932|Negativicutes	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
WH1_k127_8228437_0	926550.CLDAP_01180	1.035e-87	295.0	COG1574@1|root,COG1574@2|Bacteria	2|Bacteria	G	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WH1_k127_8230971_1	525904.Tter_0065	6.547e-204	642.0	COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
WH1_k127_8230971_2	926569.ANT_13780	3.349e-84	290.0	COG0224@1|root,COG0224@2|Bacteria,2G69I@200795|Chloroflexi	200795|Chloroflexi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
WH1_k127_8230971_0	926569.ANT_13790	5.327e-234	730.0	COG0055@1|root,COG0055@2|Bacteria,2G5JI@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
WH1_k127_8230971_3	926569.ANT_13800	1.454e-44	166.0	COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi	200795|Chloroflexi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
WH1_k127_8230971_4	926569.ANT_13810	5.845e-39	149.0	COG1077@1|root,COG1077@2|Bacteria,2G5KV@200795|Chloroflexi	200795|Chloroflexi	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
WH1_k127_8239754_1	926569.ANT_23360	4.382e-80	278.0	COG0771@1|root,COG0771@2|Bacteria,2G5VE@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WH1_k127_8239754_0	926569.ANT_23350	4.178e-124	406.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi	200795|Chloroflexi	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
WH1_k127_8239754_3	926569.ANT_23340	8.825e-08	55.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi	200795|Chloroflexi	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WH1_k127_8241140_1	1128421.JAGA01000001_gene2364	2.257e-11	68.0	COG0366@1|root,COG4733@1|root,COG0366@2|Bacteria,COG4733@2|Bacteria,2NP2D@2323|unclassified Bacteria	2|Bacteria	G	Alpha amylase, catalytic domain	apu	-	3.2.1.133,3.2.1.135,3.2.1.54,3.2.1.78	ko:K01208,ko:K01218	ko00051,ko00500,ko01100,ko02024,map00051,map00500,map01100,map02024	-	R01332,R02112,R03122,R11262	RC00467	ko00000,ko00001,ko01000	-	GH13,GH26	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_N,Big_5,CBM_20,Malt_amylase_C,SLH,fn3
WH1_k127_8241140_0	383372.Rcas_4246	1.744e-102	347.0	COG0366@1|root,COG0366@2|Bacteria,2G5NW@200795|Chloroflexi,376G5@32061|Chloroflexia	32061|Chloroflexia	G	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
WH1_k127_8256766_6	398512.JQKC01000027_gene3929	5.737e-15	79.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3WJG0@541000|Ruminococcaceae	186801|Clostridia	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
WH1_k127_8256766_4	926569.ANT_29050	4.948e-70	240.0	COG3005@1|root,COG3005@2|Bacteria,2G748@200795|Chloroflexi	200795|Chloroflexi	C	NapC/NirT cytochrome c family, N-terminal region	nrfH	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
WH1_k127_8256766_0	926569.ANT_29060	7.246e-186	594.0	COG3303@1|root,COG3303@2|Bacteria,2G5UX@200795|Chloroflexi	200795|Chloroflexi	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
WH1_k127_8256766_2	926554.KI912633_gene3916	4.162e-78	276.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
WH1_k127_8256766_5	1379698.RBG1_1C00001G1071	5.349e-47	173.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WH1_k127_8256766_1	926560.KE387023_gene2131	1.528e-110	362.0	COG3694@1|root,COG3694@2|Bacteria,1WM9D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_6
WH1_k127_8256766_3	926560.KE387023_gene2132	1.245e-70	250.0	COG4587@1|root,COG4587@2|Bacteria,1WMG7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_6
WH1_k127_8271982_1	867845.KI911784_gene1086	6.357e-81	273.0	COG1132@1|root,COG1132@2|Bacteria,2G7J5@200795|Chloroflexi,3758C@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WH1_k127_8271982_0	765420.OSCT_0755	3.263e-175	568.0	COG1132@1|root,COG1132@2|Bacteria,2G7QN@200795|Chloroflexi,374U2@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
WH1_k127_8273207_1	926550.CLDAP_09060	1.155e-89	299.0	COG0624@1|root,COG0624@2|Bacteria,2G8FI@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WH1_k127_8273207_0	1408254.T458_01170	3.095e-107	359.0	COG3191@1|root,COG3191@2|Bacteria,1TP60@1239|Firmicutes,4HD7F@91061|Bacilli,26V5I@186822|Paenibacillaceae	91061|Bacilli	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
WH1_k127_8273207_2	1111479.AXAR01000001_gene131	7.571e-13	71.0	COG4684@1|root,COG4684@2|Bacteria,1V7R3@1239|Firmicutes,4HGA5@91061|Bacilli,279TW@186823|Alicyclobacillaceae	91061|Bacilli	S	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
WH1_k127_8285015_0	383372.Rcas_0999	7.836e-57	213.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.217	ko:K05947	ko00051,map00051	-	R05768	RC00005,RC00397,RC02748	ko00000,ko00001,ko01000,ko01003	-	-	-	Osmo_MPGsynth
WH1_k127_8285015_1	1128421.JAGA01000002_gene528	1.45e-24	105.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WH1_k127_8305115_0	926569.ANT_18970	1.179e-94	313.0	COG0081@1|root,COG0081@2|Bacteria,2G6AW@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
WH1_k127_8305115_3	926569.ANT_18960	2.923e-39	153.0	COG0244@1|root,COG0244@2|Bacteria,2G6XJ@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
WH1_k127_8305115_2	926569.ANT_18950	8.09e-41	163.0	COG0222@1|root,COG0222@2|Bacteria,2G700@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
WH1_k127_8305115_1	926569.ANT_28720	3.728e-47	178.0	COG0745@1|root,COG0745@2|Bacteria,2G5TG@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WH1_k127_8309226_1	926569.ANT_20860	1.563e-52	189.0	COG0231@1|root,COG0231@2|Bacteria,2G6PY@200795|Chloroflexi	200795|Chloroflexi	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
WH1_k127_8309226_0	909663.KI867150_gene1918	1.192e-55	218.0	2FGUR@1|root,348Q2@2|Bacteria,1NZR2@1224|Proteobacteria,4322N@68525|delta/epsilon subdivisions,2WX4D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8309226_2	316274.Haur_3224	2.83e-29	118.0	COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,2G5P4@200795|Chloroflexi,374UA@32061|Chloroflexia	32061|Chloroflexia	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD_2,Helicase_C_2,RNase_T
WH1_k127_8321410_0	937777.Deipe_0063	4.082e-156	509.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
WH1_k127_8326052_1	926569.ANT_16140	4.112e-75	264.0	COG0524@1|root,COG0524@2|Bacteria,2G9QW@200795|Chloroflexi	200795|Chloroflexi	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
WH1_k127_8326052_2	926569.ANT_06810	1.349e-48	182.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_06810|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8326052_0	926569.ANT_18100	5.769e-83	278.0	COG4992@1|root,COG4992@2|Bacteria	2|Bacteria	E	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iYO844.BSU40340	Aminotran_3
WH1_k127_8327033_0	886293.Sinac_6174	3.413e-91	309.0	COG0598@1|root,COG0598@2|Bacteria,2IX61@203682|Planctomycetes	203682|Planctomycetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
WH1_k127_8327033_1	1200557.JHWV01000001_gene418	2.479e-86	291.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4H2JC@909932|Negativicutes	909932|Negativicutes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WH1_k127_8327033_2	926569.ANT_14620	5.876e-05	49.0	COG1302@1|root,COG1302@2|Bacteria,2G7GB@200795|Chloroflexi	200795|Chloroflexi	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
WH1_k127_8335519_0	926550.CLDAP_07190	3.332e-70	246.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	nosY	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
WH1_k127_8335519_1	518766.Rmar_2018	4.025e-09	60.0	COG4314@1|root,COG4314@2|Bacteria	2|Bacteria	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
WH1_k127_8348121_0	765420.OSCT_2127	5.769e-76	267.0	2CVPW@1|root,32SXZ@2|Bacteria,2G7DV@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8352295_0	926569.ANT_23380	7.397e-108	362.0	COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
WH1_k127_8352295_1	999411.HMPREF1092_01184	2.529e-31	128.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,36EE6@31979|Clostridiaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
WH1_k127_836515_0	926569.ANT_27420	8.59e-102	341.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WH1_k127_836515_1	926569.ANT_00090	2.554e-38	144.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	2|Bacteria	O	PFAM band 7 protein	hflC	-	-	-	-	-	-	-	-	-	-	-	Band_7
WH1_k127_837535_2	926550.CLDAP_40260	6.547e-14	76.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K13009,ko:K18814	-	-	-	-	ko00000,ko01000,ko01005,ko02000	9.B.67.1	-	-	Wzy_C
WH1_k127_837535_1	926569.ANT_09970	1.433e-28	120.0	COG0394@1|root,COG0394@2|Bacteria,2G7C2@200795|Chloroflexi	200795|Chloroflexi	T	PFAM low molecular weight phosphotyrosine protein phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
WH1_k127_837535_0	1173024.KI912152_gene623	1.727e-40	156.0	COG1403@1|root,COG1403@2|Bacteria,1G6DP@1117|Cyanobacteria,1JMG9@1189|Stigonemataceae	1117|Cyanobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
WH1_k127_839041_1	96561.Dole_2627	5.324e-22	107.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_2,Methyltransf_23
WH1_k127_839041_0	479434.Sthe_0858	1.003e-53	201.0	COG0500@1|root,COG2226@2|Bacteria,2G8WR@200795|Chloroflexi,27YA7@189775|Thermomicrobia	189775|Thermomicrobia	Q	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
WH1_k127_8390641_1	926550.CLDAP_39300	3.232e-80	294.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
WH1_k127_8390641_0	926569.ANT_05520	2.493e-96	327.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
WH1_k127_8390641_2	926569.ANT_05530	8.9e-07	51.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
WH1_k127_8396263_0	485916.Dtox_0803	1.103e-40	154.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,24N7A@186801|Clostridia,262C9@186807|Peptococcaceae	186801|Clostridia	S	PFAM CoA-binding domain protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
WH1_k127_841391_1	926550.CLDAP_19050	1.082e-106	349.0	COG0160@1|root,COG0160@2|Bacteria,2G5KN@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WH1_k127_841391_0	765420.OSCT_0624	7.607e-269	846.0	COG0664@1|root,COG1234@1|root,COG0664@2|Bacteria,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	MA20_22080	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Lactamase_B_2,TIR-like,cNMP_binding
WH1_k127_841391_2	329726.AM1_2452	1.788e-74	261.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1G335@1117|Cyanobacteria	1117|Cyanobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
WH1_k127_8416748_1	497964.CfE428DRAFT_1788	3.48e-12	79.0	COG1011@1|root,COG1011@2|Bacteria,46T57@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WH1_k127_8416748_0	926569.ANT_25450	6.484e-134	432.0	COG2896@1|root,COG2896@2|Bacteria,2G5JT@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
WH1_k127_8426084_2	234267.Acid_2204	6.544e-51	187.0	COG0698@1|root,COG0698@2|Bacteria	2|Bacteria	G	galactose-6-phosphate isomerase activity	upp	-	2.4.2.9,5.3.1.6	ko:K00761,ko:K01808	ko00030,ko00051,ko00240,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00240,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R00966,R01056,R09030	RC00063,RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB,UPRTase
WH1_k127_8426084_3	926569.ANT_19230	7.24e-47	177.0	COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi	200795|Chloroflexi	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
WH1_k127_8426084_0	926569.ANT_03560	5.402e-184	585.0	COG1160@1|root,COG1160@2|Bacteria,2G5M0@200795|Chloroflexi	200795|Chloroflexi	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
WH1_k127_8426084_1	926569.ANT_09460	1.815e-77	276.0	COG4856@1|root,COG4856@2|Bacteria,2G75D@200795|Chloroflexi	200795|Chloroflexi	S	PFAM YbbR family protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
WH1_k127_8427443_2	926550.CLDAP_31480	6.148e-25	112.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
WH1_k127_8427443_1	926569.ANT_10410	1.315e-39	150.0	COG0838@1|root,COG0838@2|Bacteria,2G71E@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
WH1_k127_8427443_0	926569.ANT_10420	7.785e-80	276.0	COG1005@1|root,COG1005@2|Bacteria,2G60S@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
WH1_k127_8429420_3	1396418.BATQ01000008_gene1493	7.244e-05	48.0	2CX9T@1|root,32T1J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8429420_0	1396418.BATQ01000008_gene1492	7.796e-226	717.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8429420_2	1396418.BATQ01000008_gene1490	1.358e-47	178.0	2BIYM@1|root,32D6Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8429420_1	1396418.BATQ01000008_gene1489	7.244e-132	434.0	COG1541@1|root,COG1541@2|Bacteria	2|Bacteria	H	phenylacetate-CoA ligase activity	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
WH1_k127_8467502_0	926569.ANT_09480	3.983e-75	259.0	COG0237@1|root,COG0237@2|Bacteria,2G6RQ@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
WH1_k127_8471951_0	1128421.JAGA01000003_gene3738	3.092e-46	186.0	COG4745@1|root,COG4745@2|Bacteria	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WH1_k127_8475711_0	111780.Sta7437_4018	9.551e-41	154.0	COG2337@1|root,COG2337@2|Bacteria,1GA9Y@1117|Cyanobacteria	1117|Cyanobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
WH1_k127_8475711_1	616991.JPOO01000001_gene2766	1.97e-30	123.0	COG0328@1|root,COG0328@2|Bacteria,4NNQX@976|Bacteroidetes,1I1AV@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
WH1_k127_8477357_0	926550.CLDAP_00560	0.0	1289.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
WH1_k127_8481169_0	926550.CLDAP_37530	9.254e-129	417.0	COG3842@1|root,COG3842@2|Bacteria,2G62V@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
WH1_k127_8486321_0	767817.Desgi_3960	2.763e-211	675.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,260S3@186807|Peptococcaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WH1_k127_8486321_1	1457250.BBMO01000001_gene1471	0.0008684	44.0	COG1977@1|root,arCOG00536@2157|Archaea,2XYN8@28890|Euryarchaeota,23WSK@183963|Halobacteria	183963|Halobacteria	H	COG1977 Molybdopterin converting factor, small subunit	samp1	GO:0003674,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0031386,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070647,GO:0071704,GO:1901564	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
WH1_k127_8491149_4	926569.ANT_29900	1.897e-42	159.0	COG4012@1|root,COG4012@2|Bacteria,2G6IF@200795|Chloroflexi	200795|Chloroflexi	S	Putative pyruvate format-lyase activating enzyme (DUF1786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1786
WH1_k127_8491149_1	1121377.KB906409_gene857	1.712e-116	404.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
WH1_k127_8491149_5	240015.ACP_2393	1.123e-13	74.0	COG2331@1|root,COG2331@2|Bacteria,3Y5KN@57723|Acidobacteria,2JJW0@204432|Acidobacteriia	204432|Acidobacteriia	S	Regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WH1_k127_8491149_6	1123258.AQXZ01000018_gene1035	3.411e-12	72.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
WH1_k127_8491149_2	519989.ECTPHS_02044	8.824e-71	248.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,1WWMM@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
WH1_k127_8491149_0	1499967.BAYZ01000036_gene2418	0.0	1199.0	COG0438@1|root,COG0438@2|Bacteria,2NNZH@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WH1_k127_8491149_3	1499967.BAYZ01000036_gene2419	2.816e-56	205.0	COG2152@1|root,COG2152@2|Bacteria,2NPB8@2323|unclassified Bacteria	2|Bacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
WH1_k127_8497488_0	926569.ANT_00350	3.142e-35	145.0	28MEN@1|root,2ZASA@2|Bacteria,2G97S@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8497488_2	926569.ANT_00360	1.826e-26	119.0	2EA58@1|root,334A5@2|Bacteria,2G7FD@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8497488_1	926569.ANT_00370	3.523e-27	128.0	COG1187@1|root,COG1187@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rluB	-	5.4.99.19,5.4.99.20,5.4.99.22	ko:K06178,ko:K06181,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WH1_k127_8502253_1	926550.CLDAP_01210	6.589e-29	127.0	2ETJ3@1|root,33M2W@2|Bacteria,2G7IK@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8502253_0	926569.ANT_30920	1.131e-107	361.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	dppA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WH1_k127_8505929_0	926569.ANT_10660	0.0	1038.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
WH1_k127_8505929_1	926560.KE387023_gene2133	1.093e-125	407.0	COG4586@1|root,COG4586@2|Bacteria,1WM9A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WH1_k127_8509146_0	926560.KE387023_gene3183	2.716e-254	795.0	COG1523@1|root,COG1523@2|Bacteria,1WJPP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	AMPK1_CBM,CBM_48,DUF3372,PUD
WH1_k127_8517121_1	1265505.ATUG01000001_gene4482	2.552e-39	151.0	COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,43AQ5@68525|delta/epsilon subdivisions,2X63Y@28221|Deltaproteobacteria,2MPHJ@213118|Desulfobacterales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
WH1_k127_8517121_0	1125863.JAFN01000001_gene1862	2.606e-85	293.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,42P18@68525|delta/epsilon subdivisions,2WKFV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033,ko:K12369,ko:K13890	ko02010,ko02024,map02010,map02024	M00239,M00324,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	BPD_transp_1
WH1_k127_8517121_2	1265505.ATUG01000001_gene4486	5.03e-19	89.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42N74@68525|delta/epsilon subdivisions,2WKUN@28221|Deltaproteobacteria,2MNFJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
WH1_k127_8519366_2	1288826.MSNKSG1_07243	6.215e-10	63.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,464M5@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
WH1_k127_8519366_1	582402.Hbal_1186	3.415e-11	66.0	COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria,43YKN@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
WH1_k127_8519366_0	926569.ANT_26250	2.89e-40	156.0	COG1963@1|root,COG1963@2|Bacteria,2G6XC@200795|Chloroflexi	200795|Chloroflexi	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
WH1_k127_8527894_3	401053.AciPR4_0568	4.317e-09	61.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31
WH1_k127_8527894_0	479434.Sthe_0827	1.656e-195	627.0	COG0613@1|root,COG2865@1|root,COG0613@2|Bacteria,COG2865@2|Bacteria,2G5UU@200795|Chloroflexi	200795|Chloroflexi	K	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,PHP
WH1_k127_8527894_2	926569.ANT_18320	2.243e-24	106.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K03413,ko:K07719	ko02020,ko02030,map02020,map02030	M00506,M00518	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HATPase_c,Response_reg,YcbB
WH1_k127_8527894_1	1230343.CANP01000028_gene2120	2.796e-30	121.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1S0BH@1236|Gammaproteobacteria,1JDXK@118969|Legionellales	118969|Legionellales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WH1_k127_8547415_0	926569.ANT_22460	4.422e-61	216.0	COG0571@1|root,COG0571@2|Bacteria,2G6PD@200795|Chloroflexi	200795|Chloroflexi	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
WH1_k127_8547415_1	604331.AUHY01000008_gene465	2.167e-49	188.0	COG1091@1|root,COG1091@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose reductase activity	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
WH1_k127_8547415_2	861299.J421_0072	9.258e-43	165.0	COG0116@1|root,COG0116@2|Bacteria,1ZT80@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Putative RNA methylase family UPF0020	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	UPF0020
WH1_k127_8549754_0	84531.JMTZ01000136_gene2443	1.291e-227	715.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria,1X4B6@135614|Xanthomonadales	1236|Gammaproteobacteria	O	peptidase	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
WH1_k127_8554183_0	926569.ANT_17020	3.22e-237	752.0	COG1874@1|root,COG1874@2|Bacteria,2G604@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Glycoside hydrolase family 42 domain protein	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
WH1_k127_8555024_0	768706.Desor_3513	7.968e-73	254.0	COG1410@1|root,COG1410@2|Bacteria,1VRVS@1239|Firmicutes,25EJA@186801|Clostridia,267HQ@186807|Peptococcaceae	186801|Clostridia	E	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind
WH1_k127_8555024_1	573413.Spirs_2747	1.594e-45	170.0	COG5012@1|root,COG5012@2|Bacteria,2JBHI@203691|Spirochaetes	203691|Spirochaetes	S	Dimethylamine corrinoid protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
WH1_k127_855868_4	671143.DAMO_1519	1.272e-16	79.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	AA_permease_2
WH1_k127_855868_5	926569.ANT_19170	5.126e-06	59.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	ko:K04066,ko:K07037,ko:K17266	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400,ko04147	-	-	-	Band_7
WH1_k127_855868_0	1122135.KB893134_gene3535	1.49e-97	331.0	COG2313@1|root,COG2313@2|Bacteria,1MUQU@1224|Proteobacteria,2TUKT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
WH1_k127_855868_1	1382306.JNIM01000001_gene1397	1.147e-45	169.0	COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi	200795|Chloroflexi	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
WH1_k127_8563818_0	316274.Haur_2169	1.155e-43	182.0	COG0028@1|root,COG2911@1|root,COG2931@1|root,COG3055@1|root,COG3266@1|root,COG3386@1|root,COG3409@1|root,COG0028@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3266@2|Bacteria,COG3386@2|Bacteria,COG3409@2|Bacteria,2G9CG@200795|Chloroflexi,374U7@32061|Chloroflexia	32061|Chloroflexia	G	LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,Laminin_G_3
WH1_k127_8565753_0	316274.Haur_3991	3.162e-117	398.0	COG0542@1|root,COG1186@1|root,COG0542@2|Bacteria,COG1186@2|Bacteria,2G62D@200795|Chloroflexi,3753A@32061|Chloroflexia	200795|Chloroflexi	O	ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
WH1_k127_8570512_0	926569.ANT_31200	3.133e-49	187.0	COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
WH1_k127_8570512_1	1089550.ATTH01000001_gene2112	3.52e-05	53.0	COG1074@1|root,COG1074@2|Bacteria,4PF12@976|Bacteroidetes,1FJZ4@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
WH1_k127_8609417_0	926569.ANT_01870	2.472e-81	274.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi	200795|Chloroflexi	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
WH1_k127_8609417_1	926550.CLDAP_21740	1.19e-57	216.0	COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi	200795|Chloroflexi	E	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
WH1_k127_8609417_2	1382356.JQMP01000004_gene301	9.405e-40	156.0	COG0128@1|root,COG0128@2|Bacteria,2G6S6@200795|Chloroflexi,27Y0N@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
WH1_k127_8610276_0	526227.Mesil_0256	5.388e-159	538.0	COG0457@1|root,COG1672@1|root,COG2114@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,CHAT,Guanylate_cyc,TPR_10,TPR_12,TPR_8
WH1_k127_8610276_2	326427.Cagg_2419	2.551e-62	232.0	COG0664@1|root,COG2172@1|root,COG2208@1|root,COG0664@2|Bacteria,COG2172@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,376A8@32061|Chloroflexia	32061|Chloroflexia	KT	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,SpoIIE,cNMP_binding
WH1_k127_8610276_4	926569.ANT_15190	7.474e-10	66.0	2DTJR@1|root,33KPB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8610276_3	926569.ANT_15180	3.211e-31	126.0	COG3536@1|root,COG3536@2|Bacteria,2G7H1@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
WH1_k127_8610276_1	867845.KI911784_gene1030	5.292e-88	307.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,37579@32061|Chloroflexia	32061|Chloroflexia	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WH1_k127_8617576_0	926569.ANT_14290	6.379e-108	369.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,2G6NM@200795|Chloroflexi	200795|Chloroflexi	M	Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6
WH1_k127_8617576_1	926569.ANT_09370	3.398e-06	59.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
WH1_k127_8630395_2	518766.Rmar_2438	8.939e-42	168.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria,4NG0M@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	narQ	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,PilJ
WH1_k127_8630395_1	926569.ANT_09390	7.883e-50	184.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi	200795|Chloroflexi	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
WH1_k127_8630395_3	926569.ANT_09400	2.541e-22	114.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	-	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
WH1_k127_8630395_4	864073.HFRIS_003603	9.714e-06	56.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,2VPED@28216|Betaproteobacteria	28216|Betaproteobacteria	C	electron transfer subunit	-	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind
WH1_k127_8630395_0	926569.ANT_18920	3.676e-107	360.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WH1_k127_8647761_0	926569.ANT_29930	2.495e-126	411.0	COG2116@1|root,COG2116@2|Bacteria,2G967@200795|Chloroflexi	200795|Chloroflexi	P	Formate/nitrite transporter	-	-	-	ko:K06212	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	Form_Nir_trans
WH1_k127_8647761_1	926569.ANT_02710	1.134e-13	74.0	COG1526@1|root,COG1526@2|Bacteria,2G74E@200795|Chloroflexi	200795|Chloroflexi	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
WH1_k127_8658217_1	1341151.ASZU01000025_gene3004	3.749e-10	65.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,27BHU@186824|Thermoactinomycetaceae	91061|Bacilli	S	DHH family	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WH1_k127_8658217_0	1382306.JNIM01000001_gene2748	9.154e-66	233.0	COG0130@1|root,COG0130@2|Bacteria,2G6F4@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
WH1_k127_866086_0	1396418.BATQ01000008_gene1491	1.297e-63	231.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
WH1_k127_8664309_0	926569.ANT_25700	1.101e-312	990.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
WH1_k127_8664309_1	926569.ANT_16940	2.155e-58	221.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WH1_k127_8664309_2	555079.Toce_0060	1.195e-32	132.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,42GS3@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WH1_k127_8666627_1	1463845.JOIG01000001_gene1774	4.065e-05	56.0	COG3386@1|root,COG3386@2|Bacteria,2GNV1@201174|Actinobacteria	201174|Actinobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
WH1_k127_8666627_0	1094980.Mpsy_0846	5.074e-85	289.0	COG0708@1|root,arCOG02207@2157|Archaea,2XVJ5@28890|Euryarchaeota,2N97G@224756|Methanomicrobia	224756|Methanomicrobia	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
WH1_k127_8671229_7	926569.ANT_01680	7.439e-47	174.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
WH1_k127_8671229_4	926569.ANT_01690	2.198e-70	244.0	COG0125@1|root,COG0125@2|Bacteria,2G6G2@200795|Chloroflexi	200795|Chloroflexi	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
WH1_k127_8671229_8	926569.ANT_30190	6.336e-37	143.0	COG5319@1|root,COG5319@2|Bacteria,2GA9G@200795|Chloroflexi	200795|Chloroflexi	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WH1_k127_8671229_2	926550.CLDAP_06860	1.288e-74	256.0	COG0194@1|root,COG0194@2|Bacteria,2G6EW@200795|Chloroflexi	200795|Chloroflexi	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
WH1_k127_8671229_6	765420.OSCT_2779	9.34e-48	185.0	COG0705@1|root,COG0705@2|Bacteria,2G7BZ@200795|Chloroflexi,375SV@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Rhomboid family protein	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
WH1_k127_8671229_3	926569.ANT_07440	7.504e-73	260.0	COG1355@1|root,COG1355@2|Bacteria,2G6V0@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
WH1_k127_8671229_1	479434.Sthe_1848	9.747e-103	351.0	COG1253@1|root,COG1253@2|Bacteria,2G6DE@200795|Chloroflexi,27YYU@189775|Thermomicrobia	189775|Thermomicrobia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
WH1_k127_8671229_0	1449063.JMLS01000018_gene5814	8.853e-159	531.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,26R54@186822|Paenibacillaceae	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
WH1_k127_8671229_9	1382306.JNIM01000001_gene144	3.779e-34	141.0	COG2452@1|root,COG2452@2|Bacteria,2G789@200795|Chloroflexi	200795|Chloroflexi	L	PFAM regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
WH1_k127_8671229_5	926569.ANT_02430	4.499e-59	214.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8671229_10	926569.ANT_30450	3.859e-30	127.0	28NSZ@1|root,337UE@2|Bacteria,2GA9H@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8682086_4	316274.Haur_4951	9.782e-12	80.0	COG0823@1|root,COG2373@1|root,COG3420@1|root,COG4932@1|root,COG0823@2|Bacteria,COG2373@2|Bacteria,COG3420@2|Bacteria,COG4932@2|Bacteria,2GB15@200795|Chloroflexi,377Q0@32061|Chloroflexia	32061|Chloroflexia	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8682086_0	316274.Haur_0045	1.007e-78	301.0	COG1572@1|root,COG1572@2|Bacteria,2GAID@200795|Chloroflexi,376C4@32061|Chloroflexia	32061|Chloroflexia	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8682086_2	357808.RoseRS_4292	8.547e-35	156.0	COG1572@1|root,COG4932@1|root,COG1572@2|Bacteria,COG4932@2|Bacteria,2GBU0@200795|Chloroflexi,376QE@32061|Chloroflexia	32061|Chloroflexia	M	Cna B domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
WH1_k127_8682086_1	326427.Cagg_2692	4.157e-68	241.0	COG0566@1|root,COG0566@2|Bacteria,2G6FR@200795|Chloroflexi,375AH@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
WH1_k127_8682086_3	290318.Cvib_0277	1.508e-25	111.0	COG0215@1|root,COG0215@2|Bacteria,1FDEC@1090|Chlorobi	1090|Chlorobi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
WH1_k127_8696122_1	357808.RoseRS_0733	6.113e-56	201.0	COG1943@1|root,COG1943@2|Bacteria,2G968@200795|Chloroflexi	200795|Chloroflexi	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WH1_k127_8696122_0	926569.ANT_17320	2.984e-59	216.0	29XJU@1|root,30JAW@2|Bacteria,2G9DS@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8696122_4	479434.Sthe_0925	1.501e-09	65.0	COG3870@1|root,COG3870@2|Bacteria,2GBAM@200795|Chloroflexi,27YIR@189775|Thermomicrobia	189775|Thermomicrobia	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
WH1_k127_8696122_3	926569.ANT_04430	6.869e-20	92.0	COG3870@1|root,COG3870@2|Bacteria,2G736@200795|Chloroflexi	200795|Chloroflexi	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
WH1_k127_8696122_2	926569.ANT_13410	2.924e-51	188.0	COG0477@1|root,COG2814@2|Bacteria,2GBP2@200795|Chloroflexi	200795|Chloroflexi	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH1_k127_8712983_3	1254432.SCE1572_20250	1.938e-09	59.0	COG0559@1|root,COG0683@1|root,COG0559@2|Bacteria,COG0683@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria,2Z0ZI@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WH1_k127_8712983_0	1254432.SCE1572_20250	3.692e-166	542.0	COG0559@1|root,COG0683@1|root,COG0559@2|Bacteria,COG0683@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria,2Z0ZI@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WH1_k127_8712983_2	316274.Haur_2262	3.771e-74	259.0	COG0745@1|root,COG0745@2|Bacteria,2G81R@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WH1_k127_8712983_1	1382306.JNIM01000001_gene2044	6.703e-130	445.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,2G7JR@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
WH1_k127_871555_1	709986.Deima_0860	1.857e-75	264.0	COG0584@1|root,COG0584@2|Bacteria,1WKK6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
WH1_k127_871555_0	926550.CLDAP_38670	0.0	1039.0	COG0542@1|root,COG0542@2|Bacteria,2G62D@200795|Chloroflexi	200795|Chloroflexi	O	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WH1_k127_871555_2	1137269.AZWL01000018_gene3882	4.861e-17	83.0	COG3576@1|root,COG3576@2|Bacteria,2IKU6@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
WH1_k127_8716209_0	926569.ANT_06840	3.172e-117	389.0	COG0305@1|root,COG0305@2|Bacteria,2G64D@200795|Chloroflexi	200795|Chloroflexi	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
WH1_k127_8724425_0	525904.Tter_2278	1.129e-73	260.0	COG0366@1|root,COG3280@1|root,COG4733@1|root,COG0366@2|Bacteria,COG3280@2|Bacteria,COG4733@2|Bacteria,2NP2D@2323|unclassified Bacteria	2|Bacteria	G	Alpha amylase, catalytic domain	malQ	-	2.4.1.25,3.2.1.133,3.2.1.135,3.2.1.54,3.2.1.78	ko:K00705,ko:K01208,ko:K01218	ko00051,ko00500,ko01100,ko02024,map00051,map00500,map01100,map02024	-	R01332,R02112,R03122,R05196,R11262	RC00049,RC00467	ko00000,ko00001,ko01000	-	GH13,GH26,GH77	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_N,CBM_20,Glyco_hydro_77,Malt_amylase_C,SLH,fn3
WH1_k127_8729084_0	926550.CLDAP_38260	3.139e-151	490.0	COG0507@1|root,COG0632@1|root,COG0507@2|Bacteria,COG0632@2|Bacteria,2G626@200795|Chloroflexi	200795|Chloroflexi	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
WH1_k127_8729084_4	479434.Sthe_3422	9.719e-27	122.0	COG2367@1|root,COG2367@2|Bacteria,2G7GF@200795|Chloroflexi	200795|Chloroflexi	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
WH1_k127_8729084_2	1382356.JQMP01000003_gene2466	4.338e-101	338.0	COG1173@1|root,COG1173@2|Bacteria,2G85N@200795|Chloroflexi,27YWV@189775|Thermomicrobia	189775|Thermomicrobia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
WH1_k127_8729084_3	1521187.JPIM01000070_gene652	1.446e-97	329.0	COG0601@1|root,COG0601@2|Bacteria,2G61A@200795|Chloroflexi,376I9@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
WH1_k127_8729084_1	309801.trd_0394	5.37e-142	471.0	COG4166@1|root,COG4166@2|Bacteria,2GBUU@200795|Chloroflexi,27YZK@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
WH1_k127_8731713_1	1121430.JMLG01000014_gene1967	8.375e-13	69.0	COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia,2673V@186807|Peptococcaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,Pyr_redox_2
WH1_k127_8731713_0	880073.Calab_3047	8.79e-66	233.0	COG2048@1|root,COG2048@2|Bacteria,2NQP7@2323|unclassified Bacteria	2|Bacteria	C	Heterodisulfide reductase subunit B	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
WH1_k127_8743508_0	263358.VAB18032_27136	1.249e-60	216.0	COG2890@1|root,COG2890@2|Bacteria,2GITA@201174|Actinobacteria,4DBD3@85008|Micromonosporales	201174|Actinobacteria	J	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
WH1_k127_8743508_1	1173264.KI913949_gene2383	1.397e-39	169.0	COG0784@1|root,COG2202@1|root,COG3829@1|root,COG4251@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1GPYK@1117|Cyanobacteria,1HHZI@1150|Oscillatoriales	1117|Cyanobacteria	T	COG0642 Signal transduction histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_2,PAS_3,PAS_4,PAS_9,PHY,Response_reg,dCache_1
WH1_k127_8783005_0	671143.DAMO_2604	4.029e-170	558.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
WH1_k127_8784441_0	479434.Sthe_2091	3.288e-12	79.0	COG3857@1|root,COG3857@2|Bacteria	2|Bacteria	L	exonuclease activity	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
WH1_k127_8787255_0	926569.ANT_11770	1.957e-166	534.0	COG0498@1|root,COG0784@1|root,COG0498@2|Bacteria,COG0784@2|Bacteria,2G5RK@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WH1_k127_8787255_2	926569.ANT_11760	4.901e-66	237.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WH1_k127_8787255_1	485913.Krac_1373	3.032e-148	486.0	COG0469@1|root,COG0469@2|Bacteria,2G5YE@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
WH1_k127_8807388_1	926569.ANT_28820	1.971e-159	511.0	COG1257@1|root,COG1257@2|Bacteria,2G5QV@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
WH1_k127_8807388_0	926569.ANT_09210	7.094e-176	571.0	COG0745@1|root,COG2114@1|root,COG5000@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP,dCache_1,dCache_3
WH1_k127_8823016_1	926569.ANT_15980	2.76e-61	225.0	28T1C@1|root,2ZFAN@2|Bacteria,2G9NB@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8823016_2	1123252.ATZF01000003_gene3615	7.489e-42	158.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,27BZH@186824|Thermoactinomycetaceae	91061|Bacilli	K	Transcription elongation factor, N-terminal	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
WH1_k127_8823016_0	926569.ANT_15960	7.392e-162	522.0	COG0232@1|root,COG0232@2|Bacteria,2G5VZ@200795|Chloroflexi	200795|Chloroflexi	F	PFAM metal-dependent phosphohydrolase, HD sub domain	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
WH1_k127_8829332_0	326427.Cagg_1771	4.345e-111	396.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia	32061|Chloroflexia	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_2
WH1_k127_8829332_1	1123248.KB893338_gene2319	3.825e-06	58.0	COG1404@1|root,COG2353@1|root,COG2911@1|root,COG3291@1|root,COG3342@1|root,COG1404@2|Bacteria,COG2353@2|Bacteria,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3342@2|Bacteria,4PN0F@976|Bacteroidetes,1IWTM@117747|Sphingobacteriia	976|Bacteroidetes	P	major pilin protein fima	-	-	-	-	-	-	-	-	-	-	-	-	LTD,Laminin_G_3
WH1_k127_8830531_0	926569.ANT_06590	5.494e-128	423.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	200795|Chloroflexi	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
WH1_k127_8830531_2	926569.ANT_06590	1.908e-81	280.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	200795|Chloroflexi	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
WH1_k127_8830531_1	429009.Adeg_1649	1.553e-116	385.0	COG5322@1|root,COG5322@2|Bacteria,1TSXZ@1239|Firmicutes,24992@186801|Clostridia,42EPQ@68295|Thermoanaerobacterales	186801|Clostridia	S	Shikimate quinate 5-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_DH
WH1_k127_8830531_4	7245.FBpp0260894	0.0006157	48.0	2D82N@1|root,2T8G1@2759|Eukaryota,3930P@33154|Opisthokonta,3C8AX@33208|Metazoa,3DPBM@33213|Bilateria,425JT@6656|Arthropoda,3SV54@50557|Insecta,4587U@7147|Diptera,45Z7T@7214|Drosophilidae	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8830531_3	7245.FBpp0260894	3.087e-05	48.0	2D82N@1|root,2T8G1@2759|Eukaryota,3930P@33154|Opisthokonta,3C8AX@33208|Metazoa,3DPBM@33213|Bilateria,425JT@6656|Arthropoda,3SV54@50557|Insecta,4587U@7147|Diptera,45Z7T@7214|Drosophilidae	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8834396_2	215803.DB30_2247	8.302e-18	91.0	COG4576@1|root,COG4576@2|Bacteria,1Q0YX@1224|Proteobacteria,434YC@68525|delta/epsilon subdivisions,2WZ99@28221|Deltaproteobacteria,2Z1MJ@29|Myxococcales	28221|Deltaproteobacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
WH1_k127_8834396_4	926569.ANT_07280	1.095e-08	61.0	2DCDY@1|root,2ZDSU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8834396_1	926569.ANT_07270	3.202e-92	321.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BMC
WH1_k127_8834396_0	926569.ANT_07260	4.724e-111	364.0	COG4820@1|root,COG4820@2|Bacteria	2|Bacteria	E	ethanolamine catabolic process	eutJ	-	-	ko:K04024	-	-	-	-	ko00000	-	-	-	FtsA,HSP70,MreB_Mbl,PilM_2
WH1_k127_8834396_3	926550.CLDAP_16250	7.036e-16	79.0	COG0477@1|root,COG2814@2|Bacteria,2G7NY@200795|Chloroflexi	200795|Chloroflexi	EGP	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WH1_k127_8836258_3	316274.Haur_1905	9.057e-15	82.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,376VY@32061|Chloroflexia	32061|Chloroflexia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
WH1_k127_8836258_2	1455608.JDTH01000001_gene3366	1.182e-33	148.0	COG0679@1|root,arCOG04756@2157|Archaea,2XU4B@28890|Euryarchaeota,23TA3@183963|Halobacteria	183963|Halobacteria	S	permeases	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
WH1_k127_8836258_1	926569.ANT_19930	2.942e-59	217.0	COG1413@1|root,COG1413@2|Bacteria,2G6MW@200795|Chloroflexi	200795|Chloroflexi	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
WH1_k127_8836258_0	926569.ANT_19920	4.408e-62	230.0	COG0750@1|root,COG0750@2|Bacteria,2G6GY@200795|Chloroflexi	200795|Chloroflexi	M	SMART PDZ DHR GLGF domain protein	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
WH1_k127_8838286_0	926569.ANT_15870	1.067e-28	128.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	PMT_2
WH1_k127_8851153_0	395495.Lcho_2419	1.331e-17	98.0	COG4585@1|root,COG4585@2|Bacteria,1R43J@1224|Proteobacteria,2VPEB@28216|Betaproteobacteria,1KMD2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	histidine kinase dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K02486	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CHASE5,HAMP,HATPase_c,HisKA_3,PAS,PAS_4,PAS_8,PAS_9,Response_reg
WH1_k127_8878139_2	485913.Krac_11460	1.734e-11	74.0	2CHUW@1|root,2ZECY@2|Bacteria,2G9K0@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WH1_k127_8878139_0	1089548.KI783301_gene230	4.492e-90	314.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HJPK@91061|Bacilli	91061|Bacilli	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WH1_k127_8878139_1	926569.ANT_18330	1.895e-36	139.0	COG0521@1|root,COG0521@2|Bacteria,2G7HV@200795|Chloroflexi	200795|Chloroflexi	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
WH1_k127_8887075_1	653045.Strvi_4257	2.021e-06	60.0	COG3307@1|root,COG3307@2|Bacteria,2IBT0@201174|Actinobacteria	201174|Actinobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WH1_k127_8887075_2	3075.A0A087SPS6	0.0001259	47.0	COG0201@1|root,KOG1373@2759|Eukaryota,37QKK@33090|Viridiplantae,34GR6@3041|Chlorophyta	3041|Chlorophyta	OU	Belongs to the SecY SEC61-alpha family	-	-	-	ko:K10956	ko03060,ko04141,ko04145,ko05110,map03060,map04141,map04145,map05110	M00401	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.4,3.A.5.8,3.A.5.9	-	-	Plug_translocon,SecY
WH1_k127_8887075_0	744980.TRICHSKD4_1308	5.085e-14	72.0	COG0500@1|root,COG1215@1|root,COG1215@2|Bacteria,COG2226@2|Bacteria,1QU2F@1224|Proteobacteria,2U13V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	MQ	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23,Methyltransf_25,Methyltransf_31
WH1_k127_8890437_0	926569.ANT_14670	4.076e-111	370.0	COG2414@1|root,COG2414@2|Bacteria,2G5XP@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WH1_k127_8890437_2	926550.CLDAP_35820	7.295e-30	124.0	COG3255@1|root,COG3255@2|Bacteria,2G95B@200795|Chloroflexi	200795|Chloroflexi	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
WH1_k127_8890437_3	882.DVU_1083	5.499e-19	91.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2M7S0@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WH1_k127_8890437_1	1128421.JAGA01000003_gene3510	1.364e-77	265.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WH1_k127_8899967_0	1519464.HY22_13745	7.156e-90	305.0	COG0618@1|root,COG0618@2|Bacteria,1FEID@1090|Chlorobi	1090|Chlorobi	S	3'(2'),5'-bisphosphate nucleotidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8899967_1	926569.ANT_13120	1.736e-61	219.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi	200795|Chloroflexi	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WH1_k127_8903116_0	926569.ANT_00370	3.398e-17	88.0	COG1187@1|root,COG1187@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rluB	-	5.4.99.19,5.4.99.20,5.4.99.22	ko:K06178,ko:K06181,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WH1_k127_8903116_1	926569.ANT_00380	6.596e-12	71.0	2ANS9@1|root,31DS7@2|Bacteria,2G7CA@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8916825_0	1191523.MROS_1056	2.687e-72	259.0	COG4225@1|root,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase,Glyco_hydro_88
WH1_k127_892226_0	926569.ANT_20420	2.857e-239	751.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi	200795|Chloroflexi	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WH1_k127_892226_1	1121468.AUBR01000006_gene387	2.382e-46	191.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,42F3M@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM ATP-binding region, ATPase domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
WH1_k127_8927737_1	483219.LILAB_22120	4.682e-72	249.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,42Q1B@68525|delta/epsilon subdivisions,2WKJH@28221|Deltaproteobacteria,2Z0QK@29|Myxococcales	28221|Deltaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
WH1_k127_8927737_0	112098.XP_008612065.1	4.611e-122	404.0	COG0076@1|root,KOG1383@2759|Eukaryota	2759|Eukaryota	E	sphinganine-1-phosphate aldolase activity	SGPL1	GO:0000003,GO:0001501,GO:0001553,GO:0001568,GO:0001570,GO:0001655,GO:0001667,GO:0001822,GO:0001944,GO:0002376,GO:0002520,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005938,GO:0006082,GO:0006629,GO:0006631,GO:0006643,GO:0006665,GO:0006672,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006915,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0006996,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007276,GO:0007283,GO:0007525,GO:0007527,GO:0007548,GO:0008064,GO:0008117,GO:0008150,GO:0008152,GO:0008202,GO:0008209,GO:0008210,GO:0008219,GO:0008406,GO:0008584,GO:0008585,GO:0008610,GO:0009056,GO:0009058,GO:0009267,GO:0009314,GO:0009416,GO:0009453,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009653,GO:0009791,GO:0009887,GO:0009987,GO:0009991,GO:0010171,GO:0010646,GO:0010761,GO:0010817,GO:0012501,GO:0012505,GO:0016020,GO:0016021,GO:0016042,GO:0016043,GO:0016477,GO:0016829,GO:0016830,GO:0016832,GO:0019722,GO:0019725,GO:0019752,GO:0019932,GO:0019953,GO:0022414,GO:0022602,GO:0023052,GO:0030003,GO:0030029,GO:0030036,GO:0030097,GO:0030148,GO:0030149,GO:0030154,GO:0030176,GO:0030435,GO:0030587,GO:0030832,GO:0030833,GO:0031156,GO:0031157,GO:0031158,GO:0031224,GO:0031227,GO:0031272,GO:0031273,GO:0031275,GO:0031276,GO:0031344,GO:0031345,GO:0031667,GO:0031668,GO:0031669,GO:0031984,GO:0032101,GO:0032104,GO:0032107,GO:0032271,GO:0032501,GO:0032502,GO:0032504,GO:0032535,GO:0032541,GO:0032787,GO:0032956,GO:0032970,GO:0033043,GO:0033327,GO:0033554,GO:0034641,GO:0034754,GO:0035239,GO:0035295,GO:0035556,GO:0040008,GO:0040011,GO:0040014,GO:0042175,GO:0042221,GO:0042330,GO:0042331,GO:0042445,GO:0042592,GO:0042594,GO:0042698,GO:0042742,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043254,GO:0043436,GO:0043603,GO:0043900,GO:0043934,GO:0044087,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0044703,GO:0045137,GO:0046466,GO:0046467,GO:0046545,GO:0046546,GO:0046660,GO:0046661,GO:0046956,GO:0048008,GO:0048232,GO:0048471,GO:0048511,GO:0048513,GO:0048514,GO:0048519,GO:0048523,GO:0048534,GO:0048583,GO:0048608,GO:0048609,GO:0048638,GO:0048646,GO:0048705,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0048878,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050830,GO:0050896,GO:0051128,GO:0051129,GO:0051179,GO:0051239,GO:0051493,GO:0051674,GO:0051703,GO:0051704,GO:0051707,GO:0051716,GO:0052128,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0060021,GO:0060176,GO:0060322,GO:0060323,GO:0060324,GO:0060325,GO:0060491,GO:0061061,GO:0061458,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071782,GO:0071840,GO:0071944,GO:0072001,GO:0072358,GO:0072359,GO:0072503,GO:0072507,GO:0080134,GO:0080135,GO:0090066,GO:0090702,GO:0097038,GO:0097190,GO:0098542,GO:0098771,GO:0098827,GO:0099120,GO:0099568,GO:0110053,GO:0120032,GO:0120033,GO:0120035,GO:1901360,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1902903	4.1.2.27	ko:K01634,ko:K20704	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	Pyridoxal_deC
WH1_k127_8927867_1	497321.C664_15618	7.402e-93	310.0	COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,2VH48@28216|Betaproteobacteria,2KVKA@206389|Rhodocyclales	206389|Rhodocyclales	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
WH1_k127_8927867_0	1265502.KB905936_gene2710	3.748e-138	450.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2VHCU@28216|Betaproteobacteria,4AAR9@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH1_k127_8927867_3	1216966.BAUC01000023_gene1613	0.0001568	48.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	belongs to the aldehyde dehydrogenase family	gabD	GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006105,GO:0006520,GO:0006536,GO:0006538,GO:0006540,GO:0006553,GO:0006554,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009448,GO:0009450,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0019477,GO:0019752,GO:0032787,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046440,GO:0047949,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_2847,iYL1228.KPN_00256	Aldedh
WH1_k127_8927867_2	1122931.AUAE01000011_gene1723	3.625e-07	52.0	2DR8D@1|root,33ANQ@2|Bacteria,4NYGG@976|Bacteroidetes,2FVPJ@200643|Bacteroidia,22YX8@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8930639_0	926560.KE387027_gene263	9.842e-97	324.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
WH1_k127_8940266_2	1521187.JPIM01000063_gene2483	8.156e-20	98.0	COG1807@1|root,COG1807@2|Bacteria,2G9HX@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_8940266_3	1457250.BBMO01000002_gene2593	1.304e-16	93.0	arCOG00567@1|root,arCOG00567@2157|Archaea,2XVU1@28890|Euryarchaeota,23UZV@183963|Halobacteria	183963|Halobacteria	M	glycosyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WH1_k127_8940266_0	324602.Caur_3572	1.689e-212	692.0	COG3408@1|root,COG3408@2|Bacteria,2G8ZU@200795|Chloroflexi	200795|Chloroflexi	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H
WH1_k127_8940266_1	326427.Cagg_0533	7.924e-94	325.0	COG3693@1|root,COG3693@2|Bacteria	2|Bacteria	G	endo-1,4-beta-xylanase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_35,Glyco_hydro_39,Glyco_hydro_42
WH1_k127_8940266_4	357808.RoseRS_0399	4.674e-06	53.0	COG3693@1|root,COG3693@2|Bacteria,2GBKN@200795|Chloroflexi,3781P@32061|Chloroflexia	2|Bacteria	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_35,Glyco_hydro_39,Glyco_hydro_42
WH1_k127_8943026_1	765420.OSCT_2243	4.699e-45	173.0	COG0697@1|root,COG0697@2|Bacteria,2G8KQ@200795|Chloroflexi,377W3@32061|Chloroflexia	32061|Chloroflexia	EG	EamA-like transporter family	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
WH1_k127_8943026_0	926550.CLDAP_11790	1.507e-59	218.0	COG2244@1|root,COG4485@1|root,COG2244@2|Bacteria,COG4485@2|Bacteria,2G6CM@200795|Chloroflexi	200795|Chloroflexi	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
WH1_k127_8961462_0	357808.RoseRS_0819	3.573e-95	323.0	COG0248@1|root,COG0248@2|Bacteria,2G776@200795|Chloroflexi,375D9@32061|Chloroflexia	32061|Chloroflexia	FP	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
WH1_k127_8977399_0	926550.CLDAP_19790	1.309e-114	375.0	COG1410@1|root,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi	200795|Chloroflexi	H	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
WH1_k127_8977399_1	926550.CLDAP_34010	3.729e-73	259.0	COG0524@1|root,COG0524@2|Bacteria,2G9QW@200795|Chloroflexi	200795|Chloroflexi	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
WH1_k127_8977399_2	300852.55772390	2.454e-29	119.0	COG0577@1|root,COG0577@2|Bacteria,1WIU1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH1_k127_9014141_1	316274.Haur_2849	1.753e-76	276.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2G88G@200795|Chloroflexi,37686@32061|Chloroflexia	2|Bacteria	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Laminin_G_3,Metallophos,Metallophos_C,PA,PKD,Peptidase_S8,Reprolysin_4
WH1_k127_9014141_4	113355.CM001775_gene1335	2.831e-23	101.0	2C5EY@1|root,32YQJ@2|Bacteria,1G8TB@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
WH1_k127_9014141_2	671143.DAMO_2172	1.002e-55	198.0	2DNRM@1|root,32YT2@2|Bacteria,2NQ4W@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
WH1_k127_9014141_3	926569.ANT_29030	2.182e-24	105.0	2EAGR@1|root,334K0@2|Bacteria,2G730@200795|Chloroflexi	200795|Chloroflexi	S	PFAM zinc finger, SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
WH1_k127_9014141_0	234267.Acid_1970	1.709e-89	310.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,DUF2048,Peptidase_S9
WH1_k127_9014141_5	926569.ANT_19100	1.138e-13	72.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WH1_k127_9014222_1	926569.ANT_01370	1.131e-84	287.0	COG0747@1|root,COG0747@2|Bacteria,2G5KD@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
WH1_k127_9014222_0	926569.ANT_31100	6.454e-119	402.0	COG0747@1|root,COG0747@2|Bacteria,2G7MC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WH1_k127_9016512_1	1121875.KB907547_gene2908	2.637e-27	117.0	COG0834@1|root,COG2172@1|root,COG2208@1|root,COG3829@1|root,COG0834@2|Bacteria,COG2172@2|Bacteria,COG2208@2|Bacteria,COG3829@2|Bacteria,4PPGD@976|Bacteroidetes	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9016512_3	765913.ThidrDRAFT_3584	2.211e-16	82.0	COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,1SHX0@1236|Gammaproteobacteria,1WZKQ@135613|Chromatiales	135613|Chromatiales	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS
WH1_k127_9016512_2	1229172.JQFA01000004_gene525	2.441e-22	101.0	COG0745@1|root,COG2199@1|root,COG2202@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3706@2|Bacteria,1G6W5@1117|Cyanobacteria,1HBXB@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WH1_k127_9016512_0	926569.ANT_06590	1.744e-57	212.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	200795|Chloroflexi	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
WH1_k127_9049240_3	926569.ANT_10550	4.812e-47	171.0	COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WH1_k127_9049240_1	1521187.JPIM01000006_gene1736	8.467e-105	347.0	COG1216@1|root,COG1216@2|Bacteria,2G5U8@200795|Chloroflexi,374YQ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3
WH1_k127_9049240_0	926550.CLDAP_31450	4.194e-143	468.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G5Y5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
WH1_k127_9049240_2	324602.Caur_1147	4.469e-91	305.0	COG1216@1|root,COG1216@2|Bacteria,2GBIQ@200795|Chloroflexi,374ZU@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH1_k127_9049240_4	401053.AciPR4_2842	1.013e-10	76.0	COG1807@1|root,COG1807@2|Bacteria,3Y2T0@57723|Acidobacteria,2JIGT@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9060064_0	926569.ANT_15870	6.547e-171	561.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	PMT_2
WH1_k127_9070233_2	316274.Haur_0363	1.224e-48	184.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi,3776W@32061|Chloroflexia	32061|Chloroflexia	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WH1_k127_9070233_1	316274.Haur_0364	1.634e-50	200.0	COG1307@1|root,COG1307@2|Bacteria,2G6P2@200795|Chloroflexi,374VJ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WH1_k127_9070233_0	926569.ANT_15250	8.501e-173	558.0	COG1461@1|root,COG1461@2|Bacteria,2G61Z@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Dak phosphatase	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
WH1_k127_9070233_3	926569.ANT_15240	1.853e-14	73.0	COG1302@1|root,COG1302@2|Bacteria,2G76I@200795|Chloroflexi	200795|Chloroflexi	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
WH1_k127_9074548_0	926569.ANT_23520	1.21e-57	210.0	2E3IJ@1|root,32YH0@2|Bacteria,2G7AM@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
WH1_k127_9074548_1	926569.ANT_23560	3.492e-57	204.0	2DM5T@1|root,31U0Y@2|Bacteria,2G78W@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
WH1_k127_9074548_2	1045855.DSC_11355	3.157e-17	85.0	2EGCD@1|root,33A46@2|Bacteria,1NMIX@1224|Proteobacteria,1SIUN@1236|Gammaproteobacteria,1X8EM@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
WH1_k127_9095578_3	82654.Pse7367_1552	4.158e-24	113.0	2E363@1|root,32Y5Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9095578_2	1229172.JQFA01000002_gene4445	1.256e-36	150.0	COG4430@1|root,COG4430@2|Bacteria,1GGVW@1117|Cyanobacteria	1117|Cyanobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9095578_6	760568.Desku_1263	1.6e-06	53.0	COG1149@1|root,COG1149@2|Bacteria,1VUEG@1239|Firmicutes,2503A@186801|Clostridia,267CF@186807|Peptococcaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_21,Fer4_6
WH1_k127_9095578_1	1123368.AUIS01000006_gene492	4.564e-66	232.0	COG5340@1|root,COG5340@2|Bacteria,1P6MT@1224|Proteobacteria,1RN7A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
WH1_k127_9095578_4	324925.Ppha_0825	4.052e-09	59.0	292Y4@1|root,2ZQFK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9095578_5	1458275.AZ34_02715	1.373e-06	50.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2VIY1@28216|Betaproteobacteria,4AB58@80864|Comamonadaceae	28216|Betaproteobacteria	K	Fic/DOC family N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N,HTH_13,HTH_24
WH1_k127_9095578_8	1125863.JAFN01000001_gene824	0.0002688	44.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,42MWV@68525|delta/epsilon subdivisions,2WJJZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	filamentation induced by cAMP protein Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N,HTH_24
WH1_k127_9095578_7	1345023.M467_00830	1.971e-06	57.0	2BIVC@1|root,32D3E@2|Bacteria,1VN3B@1239|Firmicutes,4I7VC@91061|Bacilli,3WFSW@539002|Bacillales incertae sedis	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9095578_0	696747.NIES39_D01320	3.893e-66	243.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria,1H919@1150|Oscillatoriales	1117|Cyanobacteria	V	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
WH1_k127_9100686_0	118173.KB235914_gene2890	1.364e-73	250.0	COG0021@1|root,COG0021@2|Bacteria,1G0GC@1117|Cyanobacteria,1H7T2@1150|Oscillatoriales	1117|Cyanobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
WH1_k127_9102596_0	326427.Cagg_0877	2.072e-47	190.0	COG1572@1|root,COG3386@1|root,COG1572@2|Bacteria,COG3386@2|Bacteria,2G9CG@200795|Chloroflexi,374U7@32061|Chloroflexia	32061|Chloroflexia	G	LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,Laminin_G_3
WH1_k127_9111017_0	926569.ANT_22490	2.689e-56	211.0	COG1354@1|root,COG1354@2|Bacteria,2G6WU@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
WH1_k127_9111017_2	469383.Cwoe_3602	7.859e-10	65.0	COG5652@1|root,COG5652@2|Bacteria,2HRVU@201174|Actinobacteria,4CTZB@84995|Rubrobacteria	84995|Rubrobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
WH1_k127_9111017_1	290397.Adeh_3396	1.105e-21	94.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WIQG@28221|Deltaproteobacteria,2YUFQ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
WH1_k127_9113848_0	1051632.TPY_3386	8.857e-55	200.0	COG1898@1|root,COG1898@2|Bacteria,1V4G5@1239|Firmicutes,24IZ8@186801|Clostridia	186801|Clostridia	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
WH1_k127_9113848_2	485913.Krac_9379	0.0009509	49.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WH1_k127_9113848_1	671143.DAMO_0882	2.367e-36	143.0	COG1028@1|root,COG1028@2|Bacteria,2NQVU@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
WH1_k127_9116491_0	1382358.JHVN01000003_gene2716	5.779e-16	83.0	COG0454@1|root,COG0454@2|Bacteria,1UJQZ@1239|Firmicutes,4ITDK@91061|Bacilli	91061|Bacilli	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
WH1_k127_9116491_1	997346.HMPREF9374_2188	2.314e-08	63.0	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,4HBZE@91061|Bacilli,27BMG@186824|Thermoactinomycetaceae	91061|Bacilli	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-TG,RHS_repeat
WH1_k127_9116621_0	926569.ANT_25910	8.887e-84	288.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	2|Bacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
WH1_k127_912662_0	926569.ANT_06600	3.159e-165	541.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
WH1_k127_912662_2	926569.ANT_06610	1.674e-47	173.0	COG0745@1|root,COG0745@2|Bacteria,2G986@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WH1_k127_912662_1	926569.ANT_06620	9.883e-80	273.0	COG0596@1|root,COG0596@2|Bacteria,2G8RI@200795|Chloroflexi	200795|Chloroflexi	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WH1_k127_9130275_1	1347369.CCAD010000081_gene2577	1.867e-22	102.0	COG1874@1|root,COG1874@2|Bacteria,1TSHK@1239|Firmicutes,4HBAR@91061|Bacilli,1ZEHU@1386|Bacillus	91061|Bacilli	G	Glycosyl hydrolases family 35	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_35
WH1_k127_9130275_0	266117.Rxyl_2989	3.656e-35	149.0	COG3395@1|root,COG3395@2|Bacteria,2HRX3@201174|Actinobacteria,4CU08@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative nucleotide-binding of sugar-metabolising enzyme	-	-	2.7.1.219,2.7.1.220	ko:K22129	-	-	-	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
WH1_k127_9140236_2	926569.ANT_08350	2.113e-54	203.0	COG0243@1|root,COG1034@1|root,COG0243@2|Bacteria,COG1034@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WH1_k127_9140236_0	247490.KSU1_D0321	1.919e-100	340.0	COG1005@1|root,COG1005@2|Bacteria,2IXH1@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
WH1_k127_9140236_1	926569.ANT_08370	7.634e-77	259.0	COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
WH1_k127_9140236_3	1128421.JAGA01000002_gene147	2.135e-39	153.0	COG0839@1|root,COG0839@2|Bacteria,2NPUC@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	nuoJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
WH1_k127_9140236_4	357808.RoseRS_2233	3.237e-34	134.0	COG0713@1|root,COG0713@2|Bacteria,2G6TP@200795|Chloroflexi,375TW@32061|Chloroflexia	32061|Chloroflexia	F	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
WH1_k127_9145472_0	1236959.BAMT01000001_gene1669	2.814e-24	119.0	COG1449@1|root,COG1449@2|Bacteria,1Q9WP@1224|Proteobacteria,2VN9S@28216|Betaproteobacteria,2KNF1@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Domain of unknown function (DUF1926)	-	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
WH1_k127_9145884_5	435591.BDI_0474	0.0007594	51.0	COG3250@1|root,COG3250@2|Bacteria,4NFPC@976|Bacteroidetes,2FPUZ@200643|Bacteroidia,22WX3@171551|Porphyromonadaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
WH1_k127_9145884_3	765420.OSCT_0417	1.718e-21	95.0	COG0642@1|root,COG2205@2|Bacteria,2G9UM@200795|Chloroflexi,3775W@32061|Chloroflexia	32061|Chloroflexia	T	Domain of unknown function (DUF4118)	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
WH1_k127_9145884_4	765420.OSCT_0966	1.737e-18	89.0	COG2331@1|root,COG2331@2|Bacteria,2G752@200795|Chloroflexi,375YG@32061|Chloroflexia	32061|Chloroflexia	S	regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WH1_k127_9145884_2	926569.ANT_19040	3.705e-33	131.0	2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9145884_0	926569.ANT_19030	2.312e-83	283.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
WH1_k127_9145884_1	485913.Krac_1351	2.005e-48	186.0	2BBY6@1|root,325GN@2|Bacteria,2G746@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9150096_0	926569.ANT_04710	7.094e-141	456.0	COG3845@1|root,COG3845@2|Bacteria,2G68B@200795|Chloroflexi	200795|Chloroflexi	S	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
WH1_k127_9150096_1	926569.ANT_04700	1.527e-81	277.0	COG4603@1|root,COG4603@2|Bacteria,2G686@200795|Chloroflexi	200795|Chloroflexi	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WH1_k127_9164983_2	497964.CfE428DRAFT_0662	1.569e-32	130.0	2EAUB@1|root,334VZ@2|Bacteria,46VV5@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9164983_0	452637.Oter_3634	1.29e-61	225.0	COG0644@1|root,COG0644@2|Bacteria,46THB@74201|Verrucomicrobia,3K8FT@414999|Opitutae	414999|Opitutae	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9164983_1	1504672.669787262	6.909e-36	137.0	COG3424@1|root,COG3424@2|Bacteria,1MUDX@1224|Proteobacteria	1224|Proteobacteria	Q	synthase	phlD	-	2.3.1.233,2.3.1.246,2.3.1.253	ko:K15431,ko:K16167,ko:K16424,ko:K19580	ko01055,ko01130,map01055,map01130	-	R06625,R10965,R10967	RC00004,RC02933,RC03463	ko00000,ko00001,ko01000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N,FAE1_CUT1_RppA
WH1_k127_9173616_0	926569.ANT_11040	5.19e-115	379.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria,2G9NH@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
WH1_k127_91763_2	926569.ANT_31440	1.045e-59	212.0	COG0064@1|root,COG0064@2|Bacteria,2G62Q@200795|Chloroflexi	200795|Chloroflexi	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
WH1_k127_91763_3	1082933.MEA186_23816	7.053e-16	86.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	ywlB	-	1.20.4.1,2.1.1.137,2.3.1.1	ko:K00537,ko:K00619,ko:K07755	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,C_GCAxxG_C_C
WH1_k127_91763_1	1304885.AUEY01000104_gene2548	1.357e-122	400.0	COG0702@1|root,COG0702@2|Bacteria,1Q438@1224|Proteobacteria,439WM@68525|delta/epsilon subdivisions,2X29K@28221|Deltaproteobacteria,2MPBK@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
WH1_k127_91763_0	448385.sce7793	7.621e-126	433.0	COG0827@1|root,COG0827@2|Bacteria,1N2RX@1224|Proteobacteria,42MGV@68525|delta/epsilon subdivisions,2WKRH@28221|Deltaproteobacteria,2Z2AU@29|Myxococcales	28221|Deltaproteobacteria	L	Eco57I restriction-modification methylase	hsdBM	-	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I
WH1_k127_9179080_0	671143.DAMO_2739	1.697e-108	362.0	COG1203@1|root,COG1203@2|Bacteria	2|Bacteria	L	DNA/RNA hybrid annealing activity	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C
WH1_k127_920318_2	1128421.JAGA01000004_gene2674	2.981e-109	358.0	COG0366@1|root,COG0366@2|Bacteria,2NQND@2323|unclassified Bacteria	2|Bacteria	G	Maltogenic Amylase, C-terminal domain	treS	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
WH1_k127_920318_0	1274374.CBLK010000003_gene3218	2.623e-133	436.0	COG0395@1|root,COG0395@2|Bacteria,1V1TN@1239|Firmicutes,4HU3Z@91061|Bacilli,26RTQ@186822|Paenibacillaceae	91061|Bacilli	G	Sugar ABC transporter permease	-	-	-	ko:K10234	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
WH1_k127_920318_1	1521187.JPIM01000001_gene890	1.498e-128	420.0	COG1175@1|root,COG1175@2|Bacteria,2GAHR@200795|Chloroflexi,37678@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10233	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
WH1_k127_9205102_1	926550.CLDAP_03240	1.967e-29	136.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	-
WH1_k127_9205102_0	449447.MAE_32140	1.39e-34	142.0	COG0863@1|root,COG1743@1|root,COG0863@2|Bacteria,COG1743@2|Bacteria,1G4WF@1117|Cyanobacteria	1117|Cyanobacteria	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
WH1_k127_9207388_1	926550.CLDAP_03010	7.902e-08	63.0	COG1388@1|root,COG1388@2|Bacteria,2G9RQ@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
WH1_k127_9207388_0	926569.ANT_03580	1.043e-44	183.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_03580|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9218591_0	926550.CLDAP_01930	5.437e-60	226.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
WH1_k127_9219292_1	926569.ANT_26970	2.333e-109	362.0	COG2010@1|root,COG2864@1|root,COG2010@2|Bacteria,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,PSCyt1
WH1_k127_9219292_3	234267.Acid_6209	4.328e-28	119.0	COG0723@1|root,COG0723@2|Bacteria,3Y7YJ@57723|Acidobacteria	57723|Acidobacteria	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
WH1_k127_9219292_2	330214.NIDE3889	1.198e-71	251.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3J0Q6@40117|Nitrospirae	2|Bacteria	C	Cytochrome b/b6/petB	qcrC	-	-	ko:K00412,ko:K03888	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B,Cytochrome_CBB3
WH1_k127_9219292_4	929712.KI912613_gene1096	8.057e-28	131.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,2HDYV@201174|Actinobacteria,4CQSB@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b subunit of the bc	-	-	-	ko:K03888	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_C,Cytochrom_C,Cytochrome_CBB3
WH1_k127_9219292_7	517722.AEUE01000002_gene2368	2.421e-05	57.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2TQW1@28211|Alphaproteobacteria,2K23A@204457|Sphingomonadales	204457|Sphingomonadales	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrom_C,Cytochrome_CBB3,FixP_N
WH1_k127_9219292_5	760192.Halhy_4417	4.43e-12	79.0	COG0607@1|root,COG2010@1|root,COG3185@1|root,COG0607@2|Bacteria,COG2010@2|Bacteria,COG3185@2|Bacteria	2|Bacteria	E	4-Hydroxyphenylpyruvate dioxygenase	-	-	5.1.99.1	ko:K00406,ko:K05606,ko:K17315	ko00190,ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,ko02010,ko02020,map00190,map00280,map00630,map00640,map00720,map01100,map01120,map01200,map02010,map02020	M00156,M00373,M00375,M00376,M00605,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1.24,3.A.1.1.30,3.D.4.3	-	-	Cytochrome_CBB3,Glyoxalase_3,Glyoxalase_4,Rhodanese
WH1_k127_9219292_6	1123508.JH636447_gene7962	3.742e-10	73.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PSCyt1
WH1_k127_9219292_0	926569.ANT_21940	5.613e-123	407.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
WH1_k127_9262183_0	937777.Deipe_0063	1.139e-86	295.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
WH1_k127_9262183_1	211114.JOEF01000025_gene191	1.168e-20	93.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,4DYF8@85010|Pseudonocardiales	201174|Actinobacteria	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
WH1_k127_9270711_3	937777.Deipe_1364	1.01e-82	279.0	COG0673@1|root,COG0673@2|Bacteria,1WM7A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WH1_k127_9270711_0	1122223.KB890696_gene268	8.514e-160	514.0	COG1063@1|root,COG1063@2|Bacteria,1WM0J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
WH1_k127_9270711_2	926550.CLDAP_36410	2.696e-99	338.0	COG3507@1|root,COG3507@2|Bacteria,2G7I9@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolases family 43	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
WH1_k127_9270711_1	1128421.JAGA01000003_gene2757	6.083e-102	335.0	COG0395@1|root,COG0395@2|Bacteria,2NQT0@2323|unclassified Bacteria	2|Bacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WH1_k127_9271072_4	926569.ANT_15240	2.307e-14	75.0	COG1302@1|root,COG1302@2|Bacteria,2G76I@200795|Chloroflexi	200795|Chloroflexi	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
WH1_k127_9271072_5	926569.ANT_15230	4.577e-11	64.0	COG0227@1|root,COG0227@2|Bacteria,2G7E5@200795|Chloroflexi	200795|Chloroflexi	J	ribosomal protein L28	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
WH1_k127_9271072_2	1033743.CAES01000011_gene4445	1.156e-68	239.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,26Q92@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WH1_k127_9271072_3	671143.DAMO_0654	1.466e-57	207.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
WH1_k127_9271072_0	671143.DAMO_0652	1.117e-171	544.0	COG0183@1|root,COG0183@2|Bacteria,2NP9T@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WH1_k127_9272126_0	1144275.COCOR_03949	1.004e-16	88.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,42MYQ@68525|delta/epsilon subdivisions,2WJM2@28221|Deltaproteobacteria,2YTST@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WH1_k127_9303524_0	926569.ANT_02630	1.414e-109	361.0	COG0226@1|root,COG0226@2|Bacteria,2G7T2@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
WH1_k127_9303524_1	926569.ANT_02640	1.622e-103	343.0	COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi	200795|Chloroflexi	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WH1_k127_9316268_0	861299.J421_4465	4.284e-138	448.0	COG1085@1|root,COG1085@2|Bacteria	2|Bacteria	C	galactose-1-phosphate uridylyltransferase	galT	GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_0842,iYL1228.KPN_00772	GalP_UDP_tr_C,GalP_UDP_transf
WH1_k127_9316268_1	1144275.COCOR_02904	2.86e-130	425.0	COG0153@1|root,COG0153@2|Bacteria,1MVQD@1224|Proteobacteria,42Y39@68525|delta/epsilon subdivisions,2WSYZ@28221|Deltaproteobacteria,2YV2T@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
WH1_k127_9339719_0	670487.Ocepr_0909	7.091e-136	439.0	COG1048@1|root,COG1048@2|Bacteria,1WIMG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acn	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
WH1_k127_9339719_1	1499967.BAYZ01000027_gene1768	1.726e-44	177.0	COG1262@1|root,COG5635@1|root,COG1262@2|Bacteria,COG5635@2|Bacteria,2NR8B@2323|unclassified Bacteria	2|Bacteria	T	NACHT domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,NACHT,NPCBM,PEGA,Pkinase
WH1_k127_9339719_2	926550.CLDAP_02480	2.404e-19	98.0	COG3209@1|root,COG3209@2|Bacteria,2G6KZ@200795|Chloroflexi	200795|Chloroflexi	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
WH1_k127_9359150_0	1128421.JAGA01000003_gene2759	1.222e-148	481.0	COG1653@1|root,COG1653@2|Bacteria,2NQZ1@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
WH1_k127_9359150_1	1128421.JAGA01000003_gene2758	7.243e-72	250.0	COG1175@1|root,COG1175@2|Bacteria,2NPDA@2323|unclassified Bacteria	2|Bacteria	G	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
WH1_k127_9400938_5	344747.PM8797T_32100	2.452e-10	69.0	COG1716@1|root,COG1716@2|Bacteria,2J45D@203682|Planctomycetes	203682|Planctomycetes	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
WH1_k127_9400938_3	1128421.JAGA01000002_gene1244	1.579e-59	215.0	COG0725@1|root,COG0725@2|Bacteria,2NQT8@2323|unclassified Bacteria	2|Bacteria	P	Bacterial extracellular solute-binding protein	modA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
WH1_k127_9400938_2	1128421.JAGA01000002_gene1243	1.111e-75	263.0	COG0555@1|root,COG0555@2|Bacteria,2NPSC@2323|unclassified Bacteria	2|Bacteria	O	Binding-protein-dependent transport system inner membrane component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
WH1_k127_9400938_0	926569.ANT_30210	8.433e-128	424.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	salK	-	2.7.13.3	ko:K07680,ko:K07778,ko:K11617,ko:K14988	ko02020,ko02024,map02020,map02024	M00476,M00479,M00481,M00522,M00754	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
WH1_k127_9400938_1	926569.ANT_30220	1.946e-80	273.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	devR	GO:0001666,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009405,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0018995,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030312,GO:0030430,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032502,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0036293,GO:0043656,GO:0043657,GO:0044174,GO:0044215,GO:0044216,GO:0044217,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070482,GO:0071944,GO:0072493,GO:0080090,GO:0080134,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1902882,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K02479,ko:K07695	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
WH1_k127_9400938_4	864051.BurJ1DRAFT_3878	1.584e-54	199.0	COG3218@1|root,COG3218@2|Bacteria,1QWQA@1224|Proteobacteria	1224|Proteobacteria	S	Ethylbenzene dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh
WH1_k127_9404199_0	926569.ANT_30500	7.606e-132	437.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
WH1_k127_9404199_1	479437.Elen_1752	2.598e-59	223.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4CUBW@84998|Coriobacteriia	84998|Coriobacteriia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WH1_k127_9430762_1	455632.SGR_6934	2.407e-178	566.0	COG1748@1|root,COG1748@2|Bacteria,2GMQ1@201174|Actinobacteria,41C3I@629295|Streptomyces griseus group	201174|Actinobacteria	E	Saccharopine dehydrogenase C-terminal domain	lys1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
WH1_k127_9430762_0	926550.CLDAP_14400	2.023e-284	892.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,2G65R@200795|Chloroflexi	200795|Chloroflexi	C	malic protein domain protein	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,Malic_M,malic
WH1_k127_9431283_0	926550.CLDAP_29060	6.602e-115	380.0	COG1562@1|root,COG1562@2|Bacteria,2G6KD@200795|Chloroflexi	200795|Chloroflexi	I	PFAM Squalene phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
WH1_k127_9435412_0	926550.CLDAP_40520	1.855e-189	602.0	COG0161@1|root,COG0161@2|Bacteria,2G62N@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
WH1_k127_9435412_1	926569.ANT_05310	1.178e-115	383.0	COG1622@1|root,COG2010@1|root,COG2197@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,COG2197@2|Bacteria,2G6C0@200795|Chloroflexi	200795|Chloroflexi	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
WH1_k127_9443266_2	671143.DAMO_0439	1.395e-05	56.0	COG4634@1|root,COG4634@2|Bacteria,2NRUB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
WH1_k127_9443266_1	402777.KB235903_gene2028	4.483e-07	61.0	COG2442@1|root,COG2442@2|Bacteria,1G8BK@1117|Cyanobacteria,1HCMT@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
WH1_k127_9443266_0	313596.RB2501_14619	4.442e-38	146.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1HXIK@117743|Flavobacteriia	976|Bacteroidetes	C	FAD linked	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
WH1_k127_944403_0	518766.Rmar_1384	7.54e-132	427.0	COG0346@1|root,COG0346@2|Bacteria,4NGE0@976|Bacteroidetes,1FJ8Q@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
WH1_k127_944403_1	867845.KI911784_gene997	3.495e-11	65.0	COG0517@1|root,COG0517@2|Bacteria,2G6TI@200795|Chloroflexi,376YQ@32061|Chloroflexia	32061|Chloroflexia	S	amino acid-binding ACT domain protein	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
WH1_k127_9455836_0	485913.Krac_0278	9.868e-51	187.0	COG0604@1|root,COG0604@2|Bacteria,2G84Q@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
WH1_k127_9455836_1	326427.Cagg_3261	3.516e-10	72.0	295YQ@1|root,2ZT9I@2|Bacteria,2G9P7@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9491135_0	864702.OsccyDRAFT_4498	3.22e-278	869.0	COG1523@1|root,COG1523@2|Bacteria,1G0PW@1117|Cyanobacteria,1H8QW@1150|Oscillatoriales	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
WH1_k127_9494909_0	1295642.H839_06519	2.328e-19	100.0	COG1525@1|root,COG3204@1|root,COG1525@2|Bacteria,COG3204@2|Bacteria,1V7X8@1239|Firmicutes,4HJJI@91061|Bacilli,1WH7K@129337|Geobacillus	91061|Bacilli	L	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD,SNase
WH1_k127_9494909_1	926550.CLDAP_11180	1.838e-12	78.0	COG0721@1|root,COG0721@2|Bacteria,2G763@200795|Chloroflexi	200795|Chloroflexi	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
WH1_k127_9496355_4	926569.ANT_25160	1.718e-18	95.0	COG0612@1|root,COG0612@2|Bacteria,2G68H@200795|Chloroflexi	200795|Chloroflexi	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WH1_k127_9496355_1	926569.ANT_25170	3.505e-131	433.0	COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WH1_k127_9496355_0	419665.Maeo_0414	1.44e-167	561.0	COG1004@1|root,COG1933@1|root,arCOG00253@2157|Archaea,arCOG03147@2157|Archaea,2XTQY@28890|Euryarchaeota,23QE5@183939|Methanococci	183939|Methanococci	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	Intein_splicing,LAGLIDADG_3,UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WH1_k127_9496355_3	1121385.AQXW01000004_gene1333	6.831e-21	96.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,1ZW7H@145357|Dermacoccaceae	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
WH1_k127_9496355_2	1128421.JAGA01000003_gene2987	1.519e-103	374.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2NQG9@2323|unclassified Bacteria	2|Bacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12,Trans_reg_C
WH1_k127_9497799_0	926569.ANT_19100	3.191e-70	244.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WH1_k127_9497799_1	926569.ANT_19090	3.966e-37	144.0	COG1232@1|root,COG1232@2|Bacteria,2G5VN@200795|Chloroflexi	200795|Chloroflexi	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
WH1_k127_9517125_0	1382356.JQMP01000004_gene667	9.073e-55	199.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi,27XYG@189775|Thermomicrobia	189775|Thermomicrobia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
WH1_k127_9517125_1	426117.M446_4350	1.338e-13	74.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,1JSU6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
WH1_k127_9529825_1	429009.Adeg_1147	4.802e-23	105.0	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,25B02@186801|Clostridia,42GFG@68295|Thermoanaerobacterales	186801|Clostridia	I	PFAM Phospholipid glycerol acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WH1_k127_9529825_0	926569.ANT_10810	1.409e-68	256.0	COG0283@1|root,COG0283@2|Bacteria,2G6I5@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
WH1_k127_9534007_0	926569.ANT_03800	7.357e-76	263.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi	200795|Chloroflexi	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
WH1_k127_9553101_2	1382356.JQMP01000003_gene2449	4.463e-14	76.0	COG4454@1|root,COG4454@2|Bacteria,2GA6H@200795|Chloroflexi,27YMB@189775|Thermomicrobia	189775|Thermomicrobia	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
WH1_k127_9553101_0	479434.Sthe_1667	2.531e-177	566.0	COG0148@1|root,COG0148@2|Bacteria,2G5VB@200795|Chloroflexi,27Y41@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
WH1_k127_9553101_1	926569.ANT_01240	1.177e-162	522.0	COG0624@1|root,COG0624@2|Bacteria,2G8AH@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WH1_k127_9555454_0	926569.ANT_11820	1.043e-32	147.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,SpoIIE
WH1_k127_9558780_1	1121448.DGI_2947	1.788e-12	79.0	COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,42PK1@68525|delta/epsilon subdivisions,2WJ65@28221|Deltaproteobacteria,2M83T@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
WH1_k127_9558780_0	1173026.Glo7428_1104	1.964e-43	163.0	COG1136@1|root,COG1136@2|Bacteria,1G17D@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC transporter	lolD	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH1_k127_956192_0	357808.RoseRS_2597	2.667e-34	132.0	COG0076@1|root,COG0076@2|Bacteria,2G76V@200795|Chloroflexi	200795|Chloroflexi	H	COGs COG0076 Glutamate decarboxylase and related PLP-dependent protein	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
WH1_k127_956192_1	32057.KB217478_gene917	3.857e-19	94.0	2DR0E@1|root,339NH@2|Bacteria	2|Bacteria	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
WH1_k127_9567297_1	112098.XP_008618512.1	3.247e-21	109.0	COG0457@1|root,KOG1124@2759|Eukaryota	2759|Eukaryota	O	cellular component assembly	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_16,TPR_8
WH1_k127_9567297_0	243090.RB6730	3.577e-27	128.0	COG0457@1|root,COG0457@2|Bacteria,2IXJ9@203682|Planctomycetes	203682|Planctomycetes	E	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9577945_3	298653.Franean1_3995	6.477e-23	100.0	COG1131@1|root,COG1131@2|Bacteria,2GNQJ@201174|Actinobacteria,4ET0F@85013|Frankiales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH1_k127_9577945_1	926569.ANT_07430	1.078e-82	289.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
WH1_k127_9577945_0	926569.ANT_07430	2.46e-87	301.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
WH1_k127_9577945_2	292459.STH2398	1.321e-47	184.0	COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
WH1_k127_9577945_4	1192034.CAP_6812	1.322e-15	85.0	2CH9R@1|root,33MNW@2|Bacteria,1QX99@1224|Proteobacteria,43C2G@68525|delta/epsilon subdivisions,2X7D2@28221|Deltaproteobacteria,2Z0BI@29|Myxococcales	28221|Deltaproteobacteria	M	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
WH1_k127_9582004_1	926569.ANT_23340	3.905e-126	412.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi	200795|Chloroflexi	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WH1_k127_9582004_0	926569.ANT_23330	7.875e-133	443.0	COG0768@1|root,COG0768@2|Bacteria,2G66C@200795|Chloroflexi	200795|Chloroflexi	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
WH1_k127_9582004_2	926569.ANT_23310	1.2e-96	326.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
WH1_k127_9582004_4	1444309.JAQG01000057_gene4902	1.196e-34	143.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,26WUX@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
WH1_k127_9582004_3	1382306.JNIM01000001_gene1621	1.079e-49	184.0	COG0515@1|root,COG0515@2|Bacteria	1382306.JNIM01000001_gene1621|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9587797_0	926550.CLDAP_00350	2.528e-61	217.0	COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi	200795|Chloroflexi	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
WH1_k127_9587797_2	926569.ANT_00520	2.149e-33	135.0	COG3063@1|root,COG3063@2|Bacteria,2G79Z@200795|Chloroflexi	200795|Chloroflexi	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	zf-B_box
WH1_k127_9587797_1	926569.ANT_00510	1.338e-47	175.0	COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
WH1_k127_9591702_1	604331.AUHY01000042_gene2025	9.652e-44	163.0	COG0406@1|root,COG0406@2|Bacteria,1WMWI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Phosphoglycerate mutase family	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
WH1_k127_9591702_0	1035308.AQYY01000002_gene390	1.554e-55	208.0	COG1893@1|root,COG1893@2|Bacteria,1UM1M@1239|Firmicutes,249J4@186801|Clostridia,264FI@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
WH1_k127_9593566_0	926569.ANT_22700	6.431e-67	231.0	COG1132@1|root,COG1132@2|Bacteria,2G7KA@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WH1_k127_9593566_1	926550.CLDAP_19600	2.523e-62	222.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WH1_k127_960723_0	926550.CLDAP_04870	1.504e-112	381.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
WH1_k127_960786_1	1125863.JAFN01000001_gene141	1.179e-07	63.0	COG0840@1|root,COG0840@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal
WH1_k127_960786_0	926550.CLDAP_25310	3.674e-12	70.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	yliI	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363	1.1.5.2	ko:K00117,ko:K21430	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	iSbBS512_1146.SbBS512_E2507	GSDH
WH1_k127_9632944_0	472759.Nhal_0228	2.67e-43	165.0	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,1RS0G@1236|Gammaproteobacteria,1WZSK@135613|Chromatiales	135613|Chromatiales	KT	PFAM PspA IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
WH1_k127_963838_0	1449126.JQKL01000014_gene3030	6.985e-145	480.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,26A1J@186813|unclassified Clostridiales	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WH1_k127_963838_1	926560.KE387023_gene3595	3.379e-134	457.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12
WH1_k127_9638458_0	926569.ANT_16960	2.528e-95	319.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi	200795|Chloroflexi	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
WH1_k127_9638458_2	1122214.AQWH01000014_gene3592	1.98e-40	161.0	COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,2TT4Y@28211|Alphaproteobacteria,2PJ8K@255475|Aurantimonadaceae	28211|Alphaproteobacteria	J	RNA 2'-O ribose methyltransferase substrate binding	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
WH1_k127_9638458_1	479434.Sthe_2294	8.919e-81	278.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi,27XZV@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
WH1_k127_964304_2	443144.GM21_0120	1.519e-13	71.0	COG0300@1|root,COG0300@2|Bacteria,1R5VP@1224|Proteobacteria,43AHS@68525|delta/epsilon subdivisions,2WTYK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WH1_k127_964304_0	649638.Trad_0723	4.935e-82	279.0	COG0300@1|root,COG0300@2|Bacteria,1WNHG@1297|Deinococcus-Thermus	2|Bacteria	S	COGs COG0300 Short-chain dehydrogenase of various substrate specificities	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WH1_k127_964304_1	1128421.JAGA01000003_gene2819	7.353e-45	167.0	COG5637@1|root,COG5637@2|Bacteria,2NRUC@2323|unclassified Bacteria	2|Bacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Polyketide_cyc
WH1_k127_964304_3	479433.Caci_6540	1.158e-07	55.0	COG5592@1|root,COG5637@1|root,COG5592@2|Bacteria,COG5637@2|Bacteria,2GMK7@201174|Actinobacteria	201174|Actinobacteria	D	cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
WH1_k127_9663640_1	1128421.JAGA01000002_gene191	6.496e-14	85.0	2EDFC@1|root,3366P@2|Bacteria	2|Bacteria	S	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
WH1_k127_9663997_3	69042.WH5701_04920	6.226e-10	62.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1G107@1117|Cyanobacteria,1GZ97@1129|Synechococcus	1117|Cyanobacteria	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
WH1_k127_9663997_0	926550.CLDAP_22690	2.174e-160	521.0	COG1215@1|root,COG2148@1|root,COG1215@2|Bacteria,COG2148@2|Bacteria,2G866@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,Glycos_transf_2
WH1_k127_9663997_1	926569.ANT_19570	4.157e-86	306.0	COG1807@1|root,COG1807@2|Bacteria,2G79E@200795|Chloroflexi	200795|Chloroflexi	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
WH1_k127_9663997_2	926569.ANT_14960	1.822e-80	284.0	COG3534@1|root,COG3534@2|Bacteria,2G8IC@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolase catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_cc
WH1_k127_9663997_4	2045.KR76_25255	3.865e-07	62.0	COG4932@1|root,COG4932@2|Bacteria,2GXWA@201174|Actinobacteria,4DUCA@85009|Propionibacteriales	201174|Actinobacteria	M	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	B_lectin,CarboxypepD_reg,Peptidase_M23,SASA
WH1_k127_9666900_2	1382304.JNIL01000001_gene290	4.653e-24	111.0	COG0596@1|root,COG0596@2|Bacteria,1VRHA@1239|Firmicutes,4IQ6T@91061|Bacilli,278RD@186823|Alicyclobacillaceae	91061|Bacilli	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
WH1_k127_9666900_0	926569.ANT_08670	3.19e-38	151.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi	200795|Chloroflexi	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
WH1_k127_9666900_1	926569.ANT_08660	8.327e-25	107.0	COG0799@1|root,COG0799@2|Bacteria,2G77A@200795|Chloroflexi	200795|Chloroflexi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
WH1_k127_9693428_2	1185876.BN8_04389	3.155e-17	89.0	COG5617@1|root,COG5617@2|Bacteria,4NFUV@976|Bacteroidetes,47NE1@768503|Cytophagia	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9693428_0	1122221.JHVI01000021_gene2457	2.349e-55	208.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WH1_k127_9693428_1	317013.NY99_14360	1.074e-28	119.0	COG0500@1|root,COG2226@2|Bacteria,1NNRW@1224|Proteobacteria,1T8Z5@1236|Gammaproteobacteria,1XBFC@135614|Xanthomonadales	135614|Xanthomonadales	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
WH1_k127_9728834_0	926550.CLDAP_07940	8.322e-78	282.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
WH1_k127_9728834_1	1128421.JAGA01000002_gene1894	1.125e-43	164.0	COG1546@1|root,COG1546@2|Bacteria,2NRMP@2323|unclassified Bacteria	2|Bacteria	S	Competence-damaged protein	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
WH1_k127_9733088_0	926569.ANT_18920	9.298e-27	113.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WH1_k127_9733088_1	864073.HFRIS_003603	8.37e-06	55.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,2VPED@28216|Betaproteobacteria	28216|Betaproteobacteria	C	electron transfer subunit	-	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind
WH1_k127_9733824_2	765420.OSCT_1792	1.02e-53	196.0	COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi,374TG@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM riboflavin biosynthesis protein RibF	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
WH1_k127_9733824_0	926569.ANT_02910	3.049e-150	490.0	COG1351@1|root,COG1351@2|Bacteria,2G8EZ@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
WH1_k127_9733824_1	485913.Krac_12542	2.34e-55	202.0	COG1063@1|root,COG1063@2|Bacteria,2G7NV@200795|Chloroflexi	200795|Chloroflexi	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
WH1_k127_974675_2	671143.DAMO_2345	1.053e-19	93.0	COG0451@1|root,COG0451@2|Bacteria,2NNT0@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	lspL	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
WH1_k127_974675_1	211165.AJLN01000084_gene1744	2.076e-29	126.0	2DDZV@1|root,32U2A@2|Bacteria,1G7V6@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_975178_0	794903.OPIT5_02790	3e-17	93.0	COG3664@1|root,COG3664@2|Bacteria,46YDP@74201|Verrucomicrobia,3K9DA@414999|Opitutae	414999|Opitutae	G	Glycosyl hydrolases family 39	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_39
WH1_k127_9759326_2	1123274.KB899416_gene2635	4.108e-24	104.0	COG3201@1|root,COG3201@2|Bacteria	2|Bacteria	H	nicotinamide mononucleotide transporter	pnuC	GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0034257,GO:0034258,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	iSDY_1059.SDY_0695	NMN_transporter
WH1_k127_9759326_0	1501230.ET33_29635	1.581e-140	455.0	COG3172@1|root,COG3172@2|Bacteria,1TQ29@1239|Firmicutes,4HBZT@91061|Bacilli,26SKF@186822|Paenibacillaceae	91061|Bacilli	H	Cytidyltransferase	-	-	2.7.1.22,2.7.7.1	ko:K06211	ko00760,ko01100,map00760,map01100	-	R00137,R02324,R03005	RC00002,RC00017	ko00000,ko00001,ko01000,ko03000	-	-	-	AAA_28,CTP_transf_like
WH1_k127_9759326_1	649638.Trad_0407	3.871e-34	134.0	COG0491@1|root,COG0491@2|Bacteria,1WIMP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WH1_k127_9759639_2	1499967.BAYZ01000103_gene3780	5.054e-25	116.0	COG0457@1|root,COG0457@2|Bacteria	1499967.BAYZ01000103_gene3780|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9759639_0	402777.KB235903_gene852	2.55e-77	272.0	COG1216@1|root,COG1216@2|Bacteria,1G0PG@1117|Cyanobacteria,1H8A8@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH1_k127_9759639_1	351607.Acel_0635	2.408e-31	135.0	COG1215@1|root,COG1215@2|Bacteria,2GJCE@201174|Actinobacteria,4EUYK@85013|Frankiales	201174|Actinobacteria	M	Glycosyl transferase family group 2	-	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
WH1_k127_9787320_5	383372.Rcas_2764	6.31e-10	64.0	2EV6B@1|root,33NM4@2|Bacteria,2G7I5@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9787320_1	1123228.AUIH01000017_gene3646	2.199e-77	263.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria,1XI3J@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
WH1_k127_9787320_3	926550.CLDAP_31590	1.317e-53	196.0	COG0807@1|root,COG1985@1|root,COG0807@2|Bacteria,COG1985@2|Bacteria,2G63D@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K01497,ko:K14652	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
WH1_k127_9787320_0	406552.NJ7G_0631	3.046e-109	364.0	COG1063@1|root,arCOG01621@2157|Archaea,2XTZT@28890|Euryarchaeota,23SIP@183963|Halobacteria	183963|Halobacteria	E	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
WH1_k127_9787320_2	706587.Desti_2993	4.852e-54	194.0	COG0720@1|root,COG0720@2|Bacteria	2|Bacteria	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
WH1_k127_9787320_4	926550.CLDAP_31620	4.234e-40	160.0	COG0438@1|root,COG0438@2|Bacteria,2G75E@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
WH1_k127_9800618_0	208439.AJAP_19850	5.644e-40	155.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria,4E21D@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Peptidase family M20 M25 M40	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WH1_k127_9809692_1	926569.ANT_27900	5.376e-21	101.0	COG4603@1|root,COG4603@2|Bacteria,2G6MU@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WH1_k127_9809692_0	926569.ANT_27890	2.497e-75	257.0	COG3845@1|root,COG3845@2|Bacteria,2G625@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
WH1_k127_9823075_0	706587.Desti_1075	2.515e-278	869.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
WH1_k127_9847178_0	771875.Ferpe_0714	2.088e-75	286.0	COG1520@1|root,COG1520@2|Bacteria,2GCVR@200918|Thermotogae	200918|Thermotogae	F	PFAM PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
WH1_k127_9847178_2	926550.CLDAP_34880	4.988e-55	221.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	MA20_15015	-	-	-	-	-	-	-	-	-	-	-	DUF1236,SH3_3
WH1_k127_9847178_1	926550.CLDAP_38700	9.3e-62	243.0	COG4447@1|root,COG4447@2|Bacteria,2G7EF@200795|Chloroflexi	200795|Chloroflexi	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9853426_0	1123368.AUIS01000020_gene1109	6.263e-107	364.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1RMUV@1236|Gammaproteobacteria,2NE6V@225057|Acidithiobacillales	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE5,CHASE8,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
WH1_k127_9853426_1	1173026.Glo7428_2204	1.127e-58	220.0	COG0784@1|root,COG0784@2|Bacteria,1GQ4W@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM response regulator receiveR	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WH1_k127_9853426_2	1318628.MARLIPOL_02845	3.498e-21	94.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WH1_k127_9853441_0	926569.ANT_21050	6.039e-176	559.0	COG0402@1|root,COG1437@1|root,COG0402@2|Bacteria,COG1437@2|Bacteria,2G6DG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,CYTH
WH1_k127_986152_0	478749.BRYFOR_08394	1.722e-67	244.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
WH1_k127_986152_1	1286171.EAL2_c08210	2.104e-25	116.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,25UTQ@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
WH1_k127_9862066_2	926569.ANT_16530	3.114e-73	254.0	COG2211@1|root,COG2211@2|Bacteria,2GA8Z@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH1_k127_9862066_3	8479.XP_005280887.1	1.924e-10	68.0	COG0666@1|root,KOG4369@1|root,KOG0504@2759|Eukaryota,KOG4369@2759|Eukaryota,38I05@33154|Opisthokonta,3BHRH@33208|Metazoa,3CU4I@33213|Bilateria,484TK@7711|Chordata,48VFT@7742|Vertebrata,4C9WP@8459|Testudines	33208|Metazoa	T	Ankyrin repeat and KH domain-containing protein 1	ANKHD1	GO:0001654,GO:0001745,GO:0001751,GO:0001754,GO:0002376,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007399,GO:0007423,GO:0008150,GO:0009605,GO:0009607,GO:0009653,GO:0009887,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010506,GO:0010507,GO:0010639,GO:0010821,GO:0010823,GO:0010927,GO:0010941,GO:0016043,GO:0019222,GO:0019730,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030182,GO:0030239,GO:0031032,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031430,GO:0031672,GO:0031674,GO:0032501,GO:0032502,GO:0032989,GO:0033043,GO:0040011,GO:0042692,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043207,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0044085,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0045087,GO:0045214,GO:0046530,GO:0048468,GO:0048513,GO:0048519,GO:0048523,GO:0048592,GO:0048646,GO:0048699,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051146,GO:0051704,GO:0051707,GO:0051716,GO:0055001,GO:0055002,GO:0060361,GO:0060548,GO:0061061,GO:0065007,GO:0070925,GO:0071840,GO:0090596,GO:0097435,GO:0099080,GO:0099081,GO:0099512,GO:1903146,GO:1903147	-	ko:K16726	-	-	-	-	ko00000,ko03036	-	-	-	Ank_2,Ank_4,KH_1
WH1_k127_9862066_1	1122223.KB890699_gene606	3.001e-83	289.0	COG0491@1|root,COG0491@2|Bacteria,1WJ5P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WH1_k127_9862066_0	926560.KE387027_gene540	4.437e-108	354.0	COG2939@1|root,COG2939@2|Bacteria,1WJMU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
WH1_k127_9869780_0	926550.CLDAP_15350	1.469e-151	492.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
WH1_k127_9875911_0	926569.ANT_12080	2.184e-123	412.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,OapA,OapA_N,Peptidase_M23
WH1_k127_989832_0	926550.CLDAP_00560	2.372e-138	445.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
WH1_k127_9901545_1	926550.CLDAP_09010	2.193e-41	158.0	COG0005@1|root,COG0005@2|Bacteria,2G5KQ@200795|Chloroflexi	200795|Chloroflexi	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
WH1_k127_9901545_0	552811.Dehly_0977	9.787e-73	255.0	COG4974@1|root,COG4974@2|Bacteria,2G6CI@200795|Chloroflexi,34D04@301297|Dehalococcoidia	301297|Dehalococcoidia	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WH1_k127_9901545_2	857293.CAAU_2345	1.102e-05	49.0	COG3847@1|root,COG3847@2|Bacteria	2|Bacteria	U	Flp Fap pilin component	pilA	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Class_IIIsignal,Flp_Fap
WH1_k127_9909080_1	525904.Tter_0276	5.753e-18	92.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH1_k127_9909080_0	869210.Marky_0686	2.939e-34	132.0	COG3358@1|root,COG3358@2|Bacteria,1WKRG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
WH1_k127_9909177_0	926569.ANT_28050	4.04e-181	578.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH1_k127_9909177_1	443144.GM21_2364	0.0005	48.0	COG2804@1|root,COG3437@1|root,COG2804@2|Bacteria,COG3437@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WKXB@28221|Deltaproteobacteria,43W1A@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM type II secretion system protein E	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,T2SSE,T2SSE_N
WH1_k127_9950866_0	266117.Rxyl_1005	3.687e-224	710.0	28HJF@1|root,2Z7UK@2|Bacteria,2ICK7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9955824_2	880073.Calab_1252	7.043e-08	56.0	COG2931@1|root,COG4677@1|root,COG2931@2|Bacteria,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	fitD	-	3.2.1.51,4.2.2.23	ko:K10297,ko:K15923,ko:K18197,ko:K19615	ko00511,ko02020,map00511,map02020	-	-	-	ko00000,ko00001,ko01000,ko02042,ko04121	-	GH95,PL11	-	Beta_helix,DUF1080,TcdA_TcdB_pore
WH1_k127_9955824_0	82654.Pse7367_1858	1.021e-82	301.0	COG2931@1|root,COG2931@2|Bacteria,1G3DW@1117|Cyanobacteria,1HAZM@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,DUF4347,HemolysinCabind
WH1_k127_9955824_1	1121920.AUAU01000011_gene193	8.735e-20	105.0	COG1572@1|root,COG3468@1|root,COG4412@1|root,COG1572@2|Bacteria,COG3468@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF2637,He_PIG,Peptidase_C2,TIG
WH1_k127_9957022_0	926550.CLDAP_05850	8.675e-123	396.0	COG1089@1|root,COG1089@2|Bacteria,2G5P2@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
WH1_k127_9957022_1	1128421.JAGA01000004_gene2626	6.776e-96	324.0	COG1089@1|root,COG1089@2|Bacteria,2NP6U@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
WH1_k127_9957022_2	926569.ANT_25400	1.468e-37	151.0	COG0539@1|root,COG0539@2|Bacteria,2G90B@200795|Chloroflexi	200795|Chloroflexi	J	PFAM RNA binding S1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S1
WH1_k127_9957022_3	479434.Sthe_2034	2.106e-22	105.0	COG4243@1|root,COG4243@2|Bacteria,2G9QC@200795|Chloroflexi,27YHV@189775|Thermomicrobia	189775|Thermomicrobia	S	VKc	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
WH1_k127_9957022_4	1173263.Syn7502_01511	2.095e-20	95.0	COG0515@1|root,COG0515@2|Bacteria,1GA6I@1117|Cyanobacteria	1117|Cyanobacteria	KLT	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
WH1_k127_9967341_0	234267.Acid_6667	7.27e-54	200.0	COG0583@1|root,COG0583@2|Bacteria,3Y4AE@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
WH1_k127_9967341_1	941639.BCO26_1454	7.625e-26	108.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,4HB6P@91061|Bacilli,1ZCAH@1386|Bacillus	91061|Bacilli	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
WH1_k127_9967495_0	1382306.JNIM01000001_gene4009	2.32e-96	339.0	COG1449@1|root,COG1449@2|Bacteria,2G5XB@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
WH1_k127_9967495_1	926692.AZYG01000072_gene2731	9.314e-60	211.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
WH1_k127_9970477_1	1121920.AUAU01000012_gene2648	1.64e-24	107.0	COG5557@1|root,COG5557@2|Bacteria,3Y3RF@57723|Acidobacteria	57723|Acidobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
WH1_k127_9970477_0	1244869.H261_18000	5.007e-59	211.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2TTE2@28211|Alphaproteobacteria,2JRY6@204441|Rhodospirillales	204441|Rhodospirillales	C	COG0437 Fe-S-cluster-containing hydrogenase components 1	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,Fer4_7
WH1_k127_9971257_3	326427.Cagg_0366	2.788e-35	136.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2GADX@200795|Chloroflexi,375PB@32061|Chloroflexia	32061|Chloroflexia	K	PFAM transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
WH1_k127_9971257_4	324602.Caur_3619	4.95e-31	126.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12,Trans_reg_C
WH1_k127_9971257_0	926550.CLDAP_25150	3.416e-140	455.0	COG0332@1|root,COG0332@2|Bacteria,2G630@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WH1_k127_9971257_1	518766.Rmar_2447	1.294e-121	410.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,1FJTQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
WH1_k127_9971257_2	1128421.JAGA01000001_gene2269	3.083e-90	304.0	COG1028@1|root,COG1028@2|Bacteria,2NQB4@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WH1_k127_9972183_1	398767.Glov_3427	8.143e-09	64.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,42RXF@68525|delta/epsilon subdivisions,2WNF1@28221|Deltaproteobacteria,43TBY@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 39	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
WH1_k127_9972183_0	926569.ANT_13130	1.625e-95	318.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH1_k127_997806_0	926569.ANT_18420	8.037e-39	157.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	DNA_alkylation,GUN4,HEAT_2,Mrr_cat,NACHT
WH1_k127_997806_1	443254.Marpi_1139	8.869e-16	88.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,2GCTB@200918|Thermotogae	200918|Thermotogae	NT	Type IV pili methyl-accepting chemotaxis transducer N-term	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PilJ
WH1_k127_9978711_0	926550.CLDAP_01930	1.158e-53	203.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
WH1_k127_9978711_1	383372.Rcas_2749	8.385e-06	50.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH1_k127_9991715_0	1123230.ARQJ01000024_gene725	1.3e-22	109.0	COG4447@1|root,COG4447@2|Bacteria,1UU3Y@1239|Firmicutes,4HCEG@91061|Bacilli,4GZH8@90964|Staphylococcaceae	91061|Bacilli	S	cellulose binding	hcf136	-	-	-	-	-	-	-	-	-	-	-	BNR
## 2812 queries scanned
## Total time (seconds): 17.07747721672058
## Rate: 164.66 q/s