## Thu Feb 19 21:24:22 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/WH2_bin.3.fa -m mmseqs --output WH2_bin.3 --output_dir /data/result/bins/wyx/eggqs50+/WH2_bin.3 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
WH2_k127_10000612_1	1408433.JHXV01000004_gene3393	7.132e-33	138.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NUDC@976|Bacteroidetes,1I7JN@117743|Flavobacteriia,2PA5J@246874|Cryomorphaceae	976|Bacteroidetes	Q	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
WH2_k127_10000612_0	1120951.AUBG01000007_gene261	3.265e-110	364.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,1HWYC@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
WH2_k127_10000671_0	1506583.JQJY01000004_gene2921	4.168e-190	609.0	COG1506@1|root,COG1506@2|Bacteria,4NFBK@976|Bacteroidetes,1HY8A@117743|Flavobacteriia,2NTHN@237|Flavobacterium	976|Bacteroidetes	E	Peptidase S9	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
WH2_k127_10003795_1	211165.AJLN01000045_gene263	3.356e-39	155.0	COG0438@1|root,COG0438@2|Bacteria,1G1SZ@1117|Cyanobacteria,1JKQS@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
WH2_k127_10003795_0	1123234.AUKI01000001_gene1884	4.888e-130	428.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,1HYC0@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
WH2_k127_10006096_0	886379.AEWI01000013_gene2187	7.467e-163	533.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,2FMY5@200643|Bacteroidia,3XJA4@558415|Marinilabiliaceae	976|Bacteroidetes	S	ABC transporter	yheS_3	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WH2_k127_10006096_2	319225.Plut_1185	0.0001125	48.0	COG3876@1|root,COG3876@2|Bacteria,1FDF0@1090|Chlorobi	1090|Chlorobi	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
WH2_k127_10006096_1	1223410.KN050846_gene2457	6.433e-59	211.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1HX06@117743|Flavobacteriia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
WH2_k127_10006111_0	643867.Ftrac_1656	2.075e-167	535.0	COG0473@1|root,COG0473@2|Bacteria,4NGUA@976|Bacteroidetes,47KD2@768503|Cytophagia	976|Bacteroidetes	CE	Isocitrate dehydrogenase	-	-	1.1.1.42,1.1.1.85	ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00432,M00535,M00740	R00267,R00268,R00994,R01899,R04426,R10052	RC00001,RC00084,RC00114,RC00417,RC00626,RC02801,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WH2_k127_10006111_2	1267211.KI669560_gene370	7.879e-100	330.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,1IQ7Q@117747|Sphingobacteriia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
WH2_k127_10006111_1	926562.Oweho_0570	8.749e-119	394.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1HYXB@117743|Flavobacteriia,2PAJA@246874|Cryomorphaceae	976|Bacteroidetes	P	PFAM Sulfate transporter family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
WH2_k127_10007261_0	1499967.BAYZ01000104_gene3690	1.722e-243	759.0	COG0286@1|root,COG0286@2|Bacteria	2|Bacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
WH2_k127_10007261_2	886377.Murru_0796	2.585e-14	79.0	29ZD6@1|root,30MBZ@2|Bacteria,4NNZI@976|Bacteroidetes,1I1X8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10007261_1	926562.Oweho_0543	4.447e-17	82.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia,2PBN1@246874|Cryomorphaceae	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HNOBA,Reg_prop,Response_reg,TPR_12,Y_Y_Y
WH2_k127_10018250_1	1313421.JHBV01000014_gene3816	6.558e-30	134.0	COG3291@1|root,COG5306@1|root,COG3291@2|Bacteria,COG5306@2|Bacteria,4NRAB@976|Bacteroidetes	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Calycin_like,PCMD
WH2_k127_10018250_0	649349.Lbys_2610	4.024e-54	194.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,47KCT@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
WH2_k127_10057168_0	595460.RRSWK_02087	5.985e-59	213.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	ydjA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WH2_k127_10057168_1	1124780.ANNU01000002_gene1618	5.538e-48	190.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,47KFS@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	mepM_1	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
WH2_k127_10057168_2	1408433.JHXV01000001_gene1029	1.619e-22	107.0	2BPRN@1|root,32IIX@2|Bacteria,4PEDZ@976|Bacteroidetes,1ICSQ@117743|Flavobacteriia,2PC0H@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10061710_2	515635.Dtur_1289	7.624e-23	113.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
WH2_k127_10061710_1	1408433.JHXV01000030_gene1408	2.891e-23	111.0	2DX5Q@1|root,343H0@2|Bacteria,4P5PC@976|Bacteroidetes,1IA62@117743|Flavobacteriia,2PB79@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10061710_0	1122176.KB903551_gene4248	6.194e-35	141.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1J098@117747|Sphingobacteriia	976|Bacteroidetes	P	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
WH2_k127_10067692_0	755732.Fluta_0377	7.565e-115	387.0	COG4191@1|root,COG4191@2|Bacteria,4NEMP@976|Bacteroidetes,1HY7G@117743|Flavobacteriia,2PAKB@246874|Cryomorphaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	vicK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
WH2_k127_10087610_2	316055.RPE_4382	3.488e-26	112.0	COG1672@1|root,COG1672@2|Bacteria,1MWQD@1224|Proteobacteria,2U2IU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	ATPase (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
WH2_k127_10087610_1	81824.XP_001749811.1	6.658e-41	174.0	2ECT2@1|root,2SIJX@2759|Eukaryota,3A4NN@33154|Opisthokonta	33154|Opisthokonta	S	Carbohydrate esterase family 3 protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,VCBS
WH2_k127_10087610_0	1288963.ADIS_1163	9.273e-84	281.0	COG0446@1|root,COG0446@2|Bacteria,4NEK6@976|Bacteroidetes,47N6I@768503|Cytophagia	976|Bacteroidetes	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WH2_k127_10145803_4	1089552.KI911559_gene2663	4.214e-10	66.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2TSCR@28211|Alphaproteobacteria,2JPN8@204441|Rhodospirillales	204441|Rhodospirillales	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
WH2_k127_10145803_2	1349785.BAUG01000037_gene2029	2.862e-34	139.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,1I1AK@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
WH2_k127_10145803_0	1121895.Q765_03380	7.244e-41	168.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1HXXP@117743|Flavobacteriia,2NS6K@237|Flavobacterium	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10145803_3	269798.CHU_3270	6.872e-12	78.0	COG3117@1|root,COG3117@2|Bacteria,4NRIN@976|Bacteroidetes,47R6J@768503|Cytophagia	976|Bacteroidetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
WH2_k127_10145803_1	1189612.A33Q_4255	2.11e-35	140.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,47KQX@768503|Cytophagia	976|Bacteroidetes	S	CBS domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
WH2_k127_10150686_1	1042376.AFPK01000040_gene2098	4.428e-83	297.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,1HWM5@117743|Flavobacteriia,406MN@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
WH2_k127_10150686_0	1296415.JACC01000036_gene1181	1.194e-117	387.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,1HWPZ@117743|Flavobacteriia,2YI2C@290174|Aquimarina	976|Bacteroidetes	T	PhoH-like protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
WH2_k127_10150686_2	743722.Sph21_2529	1.883e-65	233.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1IQEU@117747|Sphingobacteriia	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	fjo14	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
WH2_k127_10150686_3	504487.JCM19302_3319	4.219e-19	100.0	COG1359@1|root,COG1359@2|Bacteria,4NSV0@976|Bacteroidetes,1I40Y@117743|Flavobacteriia	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
WH2_k127_10150686_4	111780.Sta7437_2551	3.106e-14	85.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,3VJQ2@52604|Pleurocapsales	1117|Cyanobacteria	O	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
WH2_k127_10173782_3	1121904.ARBP01000007_gene2984	1.418e-05	55.0	COG4775@1|root,COG4775@2|Bacteria,4NF9Y@976|Bacteroidetes,47KUK@768503|Cytophagia	976|Bacteroidetes	M	PFAM surface antigen variable number repeat	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
WH2_k127_10173782_2	755732.Fluta_0111	9.216e-55	200.0	COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,1HXW4@117743|Flavobacteriia,2PAZY@246874|Cryomorphaceae	976|Bacteroidetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WH2_k127_10173782_0	1122973.KB904311_gene817	2.089e-94	316.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,2FM21@200643|Bacteroidia,22WZG@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
WH2_k127_10173782_1	1408433.JHXV01000007_gene2956	1.221e-68	246.0	COG0596@1|root,COG0596@2|Bacteria,4NDZI@976|Bacteroidetes,1HXF6@117743|Flavobacteriia,2PAPJ@246874|Cryomorphaceae	976|Bacteroidetes	S	Serine aminopeptidase, S33	ybfF	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WH2_k127_10179686_0	1233950.IW22_15425	3.393e-10	72.0	COG3509@1|root,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,CBM_2,CBM_4_9,Esterase_phd,Glyco_hydro_16,RicinB_lectin_2,SLH
WH2_k127_10179686_1	1356852.N008_05060	9.197e-06	57.0	COG3509@1|root,COG3509@2|Bacteria,4NHFS@976|Bacteroidetes,47RR1@768503|Cytophagia	976|Bacteroidetes	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase_phd
WH2_k127_10180811_1	313590.MED134_09161	2.097e-54	199.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1HYBR@117743|Flavobacteriia,37DT6@326319|Dokdonia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WH2_k127_10180811_2	1120966.AUBU01000001_gene740	1.987e-33	135.0	COG3437@1|root,COG3437@2|Bacteria,4NP14@976|Bacteroidetes,47Q84@768503|Cytophagia	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,SpoIIE
WH2_k127_10180811_0	448385.sce6403	9.279e-187	612.0	COG0476@1|root,COG0778@1|root,COG0476@2|Bacteria,COG0778@2|Bacteria,1QUMS@1224|Proteobacteria,42P3N@68525|delta/epsilon subdivisions,2WKH0@28221|Deltaproteobacteria,2YZ4H@29|Myxococcales	28221|Deltaproteobacteria	CH	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
WH2_k127_10180811_3	1120968.AUBX01000010_gene1121	3.355e-20	102.0	28IFK@1|root,2Z8HB@2|Bacteria,4NH1P@976|Bacteroidetes,47NVI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10181536_0	983917.RGE_21830	1.012e-215	675.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2W18C@28216|Betaproteobacteria,1KP96@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WH2_k127_10181536_3	866536.Belba_0662	1.506e-05	49.0	COG1729@1|root,COG1729@2|Bacteria,4PKGA@976|Bacteroidetes,47Y51@768503|Cytophagia	976|Bacteroidetes	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
WH2_k127_10181536_2	926562.Oweho_3113	3.242e-59	223.0	COG1807@1|root,COG1807@2|Bacteria,4P3XI@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WH2_k127_10181536_1	926562.Oweho_2361	2.126e-68	248.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,1HXBC@117743|Flavobacteriia,2PBQF@246874|Cryomorphaceae	976|Bacteroidetes	M	Peptidase family M23	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WH2_k127_1018700_1	929556.Solca_0931	2.866e-25	109.0	COG1572@1|root,COG1572@2|Bacteria,4PM6M@976|Bacteroidetes,1J0JA@117747|Sphingobacteriia	976|Bacteroidetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB
WH2_k127_1018700_0	529818.AMSG_12243T0	2.257e-50	200.0	2D5D4@1|root,2SY53@2759|Eukaryota	529818.AMSG_12243T0|-	S	Thecamonas trahens ATCC 50062	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10194699_1	1408433.JHXV01000022_gene3142	9.01e-119	396.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10194699_0	1408433.JHXV01000020_gene3544	3.747e-215	683.0	COG1629@1|root,COG4771@2|Bacteria,4NTQD@976|Bacteroidetes,1IKD4@117743|Flavobacteriia,2PA9C@246874|Cryomorphaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
WH2_k127_10203959_0	929556.Solca_2664	5.629e-164	552.0	COG2374@1|root,COG3209@1|root,COG3210@1|root,COG3391@1|root,COG4886@1|root,COG4932@1|root,COG5492@1|root,COG2374@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
WH2_k127_10218766_0	755732.Fluta_2160	4.848e-317	978.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1HXXA@117743|Flavobacteriia,2PAEA@246874|Cryomorphaceae	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
WH2_k127_10218766_5	504487.JCM19302_3270	1.063e-47	173.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,1I1Y0@117743|Flavobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
WH2_k127_10218766_4	867902.Ornrh_1550	2.117e-57	205.0	COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,1HXJG@117743|Flavobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
WH2_k127_10218766_1	1433126.BN938_1292	1.951e-100	332.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,2FNKI@200643|Bacteroidia,22UY1@171550|Rikenellaceae	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
WH2_k127_10218766_3	1406840.Q763_14610	7.128e-74	250.0	COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,1I18G@117743|Flavobacteriia,2NSUS@237|Flavobacterium	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
WH2_k127_10218766_2	1168034.FH5T_04200	5.466e-82	280.0	COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,2FNJ6@200643|Bacteroidia	976|Bacteroidetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
WH2_k127_10218766_7	1408433.JHXV01000007_gene2900	2.937e-18	87.0	COG0690@1|root,COG0690@2|Bacteria,4PFHS@976|Bacteroidetes,1IC4N@117743|Flavobacteriia,2PB91@246874|Cryomorphaceae	976|Bacteroidetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
WH2_k127_10218766_6	755732.Fluta_2153	1.693e-21	93.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,1HWMU@117743|Flavobacteriia,2PA6H@246874|Cryomorphaceae	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
WH2_k127_10233583_2	349521.HCH_04832	4.377e-48	180.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,1RR92@1236|Gammaproteobacteria,1XKPB@135619|Oceanospirillales	135619|Oceanospirillales	M	CMP-N-acetylneuraminic acid synthetase	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3
WH2_k127_10233583_0	349521.HCH_04831	1.685e-162	526.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1XII2@135619|Oceanospirillales	1236|Gammaproteobacteria	H	Glutamate-1-semialdehyde aminotransferase	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,CTP_transf_3
WH2_k127_10233583_1	1144319.PMI16_04699	4.66e-85	289.0	COG1028@1|root,COG1028@2|Bacteria,1R5GA@1224|Proteobacteria,2WC56@28216|Betaproteobacteria,4770J@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH2_k127_10239707_1	1094466.KQS_02945	1.371e-48	179.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,1I1B5@117743|Flavobacteriia,2NS85@237|Flavobacterium	976|Bacteroidetes	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
WH2_k127_10239707_0	1121904.ARBP01000001_gene5388	7.182e-79	290.0	COG2133@1|root,COG5276@1|root,COG5492@1|root,COG2133@2|Bacteria,COG5276@2|Bacteria,COG5492@2|Bacteria,4PPMR@976|Bacteroidetes,47YPB@768503|Cytophagia	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHU_C,DUF4347,GSDH,He_PIG,LVIVD,Laminin_G_3,PKD,Reprolysin_4,SLH,TSP_3
WH2_k127_10239707_2	1122176.KB903602_gene5067	1.038e-29	137.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IXJP@117747|Sphingobacteriia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB,TIG
WH2_k127_10239935_0	755732.Fluta_1812	1.062e-155	521.0	COG3536@1|root,COG3536@2|Bacteria,4PKQ9@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10245360_2	927658.AJUM01000037_gene1874	2.243e-08	66.0	2DP4F@1|root,330H1@2|Bacteria,4NX9Z@976|Bacteroidetes,2FVZZ@200643|Bacteroidia,3XKEM@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10245360_0	1168289.AJKI01000002_gene2553	1.581e-39	169.0	COG1595@1|root,COG1595@2|Bacteria,4NQ7S@976|Bacteroidetes,2FTDI@200643|Bacteroidia,3XK6J@558415|Marinilabiliaceae	976|Bacteroidetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH2_k127_10245360_1	526225.Gobs_4095	1.19e-10	74.0	2DR33@1|root,339YQ@2|Bacteria,2GZJE@201174|Actinobacteria,4EV5M@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10245360_3	391603.FBALC1_04492	0.0001117	55.0	COG2706@1|root,COG2706@2|Bacteria,4NMAT@976|Bacteroidetes	976|Bacteroidetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
WH2_k127_10245992_0	1120965.AUBV01000006_gene2375	9.595e-214	676.0	COG3256@1|root,COG3256@2|Bacteria,4NG9H@976|Bacteroidetes,47K63@768503|Cytophagia	976|Bacteroidetes	P	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
WH2_k127_10245992_1	1048339.KB913029_gene2289	1.917e-102	353.0	COG0029@1|root,COG0157@1|root,COG0029@2|Bacteria,COG0157@2|Bacteria,2I2IJ@201174|Actinobacteria,4ERDS@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
WH2_k127_10245992_2	1434325.AZQN01000003_gene2783	4.673e-06	49.0	COG0379@1|root,COG0379@2|Bacteria,4NDVX@976|Bacteroidetes,47MXK@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
WH2_k127_10253752_2	760192.Halhy_0935	2.318e-51	201.0	COG2304@1|root,COG2304@2|Bacteria,4NFQQ@976|Bacteroidetes,1IQP4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM N-terminal double-transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA
WH2_k127_10253752_0	929556.Solca_0932	4.431e-112	380.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,1IRB4@117747|Sphingobacteriia	976|Bacteroidetes	F	Dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
WH2_k127_10253752_4	1408433.JHXV01000001_gene927	5.788e-17	89.0	COG1729@1|root,COG1729@2|Bacteria,4P7J6@976|Bacteroidetes,1IBBB@117743|Flavobacteriia,2PC55@246874|Cryomorphaceae	976|Bacteroidetes	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10253752_1	1408433.JHXV01000001_gene928	3.99e-76	261.0	COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,1HX7M@117743|Flavobacteriia,2PAPD@246874|Cryomorphaceae	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
WH2_k127_10253752_3	1121481.AUAS01000003_gene3868	1.121e-34	138.0	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,47QCM@768503|Cytophagia	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
WH2_k127_10274597_0	1227739.Hsw_2817	1.632e-54	204.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,47RJR@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
WH2_k127_10274597_1	1279009.ADICEAN_03140	0.0007563	48.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,47MR6@768503|Cytophagia	976|Bacteroidetes	G	PFAM Alpha amylase, catalytic	-	GO:0000272,GO:0000287,GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0016020,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0019867,GO:0030246,GO:0030247,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046872,GO:0071704,GO:1901575,GO:2001070	3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54	ko:K01176,ko:K01208	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,BACON
WH2_k127_10279489_0	927658.AJUM01000017_gene3135	1.909e-173	559.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,2FNMG@200643|Bacteroidia,3XJ19@558415|Marinilabiliaceae	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WH2_k127_10279489_1	1123234.AUKI01000011_gene1385	1.206e-94	323.0	COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,1HXX8@117743|Flavobacteriia	976|Bacteroidetes	M	Murein transglycosylase	mltD_2	-	-	-	-	-	-	-	-	-	-	-	SLT
WH2_k127_10279489_2	755732.Fluta_2051	2.849e-70	251.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1HZEV@117743|Flavobacteriia,2PBMM@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
WH2_k127_10279489_3	1005048.CFU_0808	5.658e-12	66.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,2VQ02@28216|Betaproteobacteria,472YX@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
WH2_k127_10301046_4	926562.Oweho_2549	1.261e-45	171.0	COG2972@1|root,COG2972@2|Bacteria,4PI9T@976|Bacteroidetes,1ICCN@117743|Flavobacteriia,2PBQV@246874|Cryomorphaceae	976|Bacteroidetes	T	regulator of cell autolysis	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
WH2_k127_10301046_0	1408433.JHXV01000038_gene2216	8.441e-167	539.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1HYIP@117743|Flavobacteriia,2PBI8@246874|Cryomorphaceae	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10301046_1	926562.Oweho_1031	1.964e-132	452.0	COG0308@1|root,COG0308@2|Bacteria,4NGTZ@976|Bacteroidetes,1HY7M@117743|Flavobacteriia	976|Bacteroidetes	E	Aminopeptidase N	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
WH2_k127_10301046_3	1235803.C825_01515	1.066e-47	184.0	COG3177@1|root,COG3177@2|Bacteria,4NHPW@976|Bacteroidetes,2FQXS@200643|Bacteroidia,22YA0@171551|Porphyromonadaceae	976|Bacteroidetes	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
WH2_k127_10301046_2	1453500.AT05_10425	1.32e-62	217.0	COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,1I18N@117743|Flavobacteriia	976|Bacteroidetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
WH2_k127_10301046_5	471854.Dfer_4340	1.492e-41	155.0	COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,47P7P@768503|Cytophagia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
WH2_k127_10313867_0	485917.Phep_3722	4.752e-255	799.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,1IPBZ@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH2_k127_10313867_2	675806.VII_000721	1.372e-05	55.0	2AXJ2@1|root,31PJ0@2|Bacteria,1QM8P@1224|Proteobacteria,1TJGN@1236|Gammaproteobacteria,1Y17I@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10313867_1	1124780.ANNU01000013_gene3794	8.784e-85	289.0	COG2220@1|root,COG2220@2|Bacteria,4NENZ@976|Bacteroidetes,47JT5@768503|Cytophagia	976|Bacteroidetes	S	COGs COG2220 Zn-dependent hydrolase of the beta-lactamase fold	romA	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
WH2_k127_10316111_2	153721.MYP_3989	2.509e-33	142.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,47MGN@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
WH2_k127_10316111_1	1121288.AULL01000011_gene1101	2.444e-48	188.0	COG1503@1|root,COG1503@2|Bacteria,4NHF3@976|Bacteroidetes,1I0UG@117743|Flavobacteriia,3ZSH3@59732|Chryseobacterium	976|Bacteroidetes	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10316111_0	313596.RB2501_15504	1.758e-206	653.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,1HXI7@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
WH2_k127_10326455_0	1090319.KE386571_gene2976	4.109e-96	337.0	COG0223@1|root,COG0223@2|Bacteria,1NN5V@1224|Proteobacteria,2TTHZ@28211|Alphaproteobacteria,2K41C@204457|Sphingomonadales	204457|Sphingomonadales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10326455_1	1089550.ATTH01000001_gene670	3.426e-28	118.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes	976|Bacteroidetes	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WH2_k127_10329568_1	517418.Ctha_2624	6.057e-113	383.0	COG4166@1|root,COG4166@2|Bacteria	2|Bacteria	E	transmembrane transport	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
WH2_k127_10329568_4	1124780.ANNU01000023_gene3189	9.214e-33	144.0	28KKN@1|root,2ZA5E@2|Bacteria,4NMKH@976|Bacteroidetes,47PT5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10329568_2	755732.Fluta_0921	5.558e-60	219.0	COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,1HXG8@117743|Flavobacteriia,2PAWA@246874|Cryomorphaceae	976|Bacteroidetes	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
WH2_k127_10329568_0	929562.Emtol_3294	5.136e-115	387.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,47K32@768503|Cytophagia	976|Bacteroidetes	E	chorismate mutase	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
WH2_k127_10329568_3	391603.FBALC1_07508	3.702e-44	169.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,4NUCQ@976|Bacteroidetes	976|Bacteroidetes	C	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
WH2_k127_1034204_1	700598.Niako_6767	1.277e-53	201.0	COG0726@1|root,COG0726@2|Bacteria,4NQKC@976|Bacteroidetes	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1034204_3	666685.R2APBS1_3072	1.559e-28	132.0	COG3533@1|root,COG3533@2|Bacteria,1QZ4E@1224|Proteobacteria,1S48V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1034204_2	886379.AEWI01000052_gene2669	1.85e-39	161.0	COG0297@1|root,COG0297@2|Bacteria,4PP8M@976|Bacteroidetes,2G144@200643|Bacteroidia,3XJT9@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH2_k127_1034204_0	329726.AM1_3609	3.094e-54	194.0	COG1087@1|root,COG1087@2|Bacteria,1GDSP@1117|Cyanobacteria	1117|Cyanobacteria	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	-
WH2_k127_10350952_0	1453500.AT05_07745	1.054e-162	514.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1HWM2@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
WH2_k127_10350952_2	1288963.ADIS_0660	2.046e-18	87.0	COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,47S1U@768503|Cytophagia	976|Bacteroidetes	C	PFAM ATP synthase, Delta Epsilon chain, beta-sandwich domain	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
WH2_k127_10350952_1	1123400.KB904752_gene837	6.572e-26	123.0	COG0823@1|root,COG2304@1|root,COG2931@1|root,COG4932@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,1S1HJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cadherin_3,DUF4214,DUF4347,He_PIG,HemolysinCabind,PATR,VCBS
WH2_k127_10354179_0	1237149.C900_04332	6.639e-32	138.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,47M95@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
WH2_k127_10354179_1	1408433.JHXV01000001_gene651	7.858e-23	103.0	COG2885@1|root,COG2885@2|Bacteria,4PISD@976|Bacteroidetes,1ICSE@117743|Flavobacteriia,2PBZT@246874|Cryomorphaceae	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10368395_1	927658.AJUM01000040_gene920	1.618e-51	185.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,2FMPT@200643|Bacteroidia,3XJGJ@558415|Marinilabiliaceae	976|Bacteroidetes	M	MraW methylase family	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
WH2_k127_10368395_2	867902.Ornrh_0576	7.583e-41	156.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,1I198@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
WH2_k127_10368395_0	760192.Halhy_0634	5.805e-52	199.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1IW1C@117747|Sphingobacteriia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
WH2_k127_10396957_0	880070.Cycma_1057	2.837e-143	479.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,47JP2@768503|Cytophagia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
WH2_k127_10396957_1	926562.Oweho_3551	5.957e-21	97.0	COG0239@1|root,COG0239@2|Bacteria,4P9SD@976|Bacteroidetes,1IEE9@117743|Flavobacteriia,2PBA2@246874|Cryomorphaceae	976|Bacteroidetes	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
WH2_k127_10403499_0	1408433.JHXV01000029_gene3104	4.743e-128	430.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia,2PA6D@246874|Cryomorphaceae	976|Bacteroidetes	DM	Chain length determinant protein	wzc	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
WH2_k127_10433601_2	1157637.KB892135_gene3612	1.793e-55	207.0	COG3509@1|root,COG3509@2|Bacteria,2GMTA@201174|Actinobacteria	201174|Actinobacteria	Q	Esterase, phb depolymerase family	phaZ1	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
WH2_k127_10433601_3	742817.HMPREF9449_01309	7.657e-45	178.0	COG0300@1|root,COG0300@2|Bacteria,4NIAI@976|Bacteroidetes,2FRZY@200643|Bacteroidia,22XM7@171551|Porphyromonadaceae	976|Bacteroidetes	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
WH2_k127_10433601_0	742725.HMPREF9450_01501	5.613e-130	425.0	COG1902@1|root,COG1902@2|Bacteria,4NF98@976|Bacteroidetes,2FNNA@200643|Bacteroidia,22VH1@171550|Rikenellaceae	976|Bacteroidetes	C	NADH:flavin oxidoreductase / NADH oxidase family	namA	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
WH2_k127_10433601_1	1223410.KN050846_gene1923	3.384e-126	407.0	COG0189@1|root,COG0189@2|Bacteria,4NED4@976|Bacteroidetes,1HZ04@117743|Flavobacteriia	976|Bacteroidetes	HJ	Ribosomal protein S6 modification	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
WH2_k127_10463466_2	763034.HMPREF9446_01851	1.344e-77	263.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
WH2_k127_10463466_3	1408813.AYMG01000010_gene623	1.054e-40	153.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,1ISVX@117747|Sphingobacteriia	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
WH2_k127_10463466_0	1408433.JHXV01000005_gene2228	1.156e-163	544.0	COG1752@1|root,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,1HWZP@117743|Flavobacteriia,2PBJS@246874|Cryomorphaceae	976|Bacteroidetes	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	POTRA,Patatin
WH2_k127_10463466_1	1313421.JHBV01000029_gene1942	2.341e-85	290.0	COG0614@1|root,COG0614@2|Bacteria,4NI2Y@976|Bacteroidetes,1IPYQ@117747|Sphingobacteriia	976|Bacteroidetes	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	fecB	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
WH2_k127_10474422_0	313606.M23134_00148	3.247e-50	205.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,4NDZQ@976|Bacteroidetes,47MGN@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
WH2_k127_10478623_0	929556.Solca_2664	5.912e-219	729.0	COG2374@1|root,COG3209@1|root,COG3210@1|root,COG3391@1|root,COG4886@1|root,COG4932@1|root,COG5492@1|root,COG2374@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
WH2_k127_10495367_1	143224.JQMD01000002_gene1540	4.418e-20	95.0	COG0457@1|root,COG3920@1|root,COG0457@2|Bacteria,COG3920@2|Bacteria,4NINT@976|Bacteroidetes,1HWYS@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,TPR_12,TPR_8
WH2_k127_10495367_0	1237149.C900_04348	9.165e-137	449.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47M80@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
WH2_k127_10558359_1	1408433.JHXV01000012_gene3977	3.334e-135	462.0	COG1404@1|root,COG1404@2|Bacteria,4NTWX@976|Bacteroidetes,1I4GV@117743|Flavobacteriia,2PBAJ@246874|Cryomorphaceae	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WH2_k127_10558359_4	504472.Slin_0367	4.718e-38	149.0	COG4096@1|root,COG4096@2|Bacteria,4NNKI@976|Bacteroidetes,47QPJ@768503|Cytophagia	976|Bacteroidetes	V	Type I restriction enzyme R Protein	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
WH2_k127_10558359_2	1123253.AUBD01000010_gene2155	1.887e-120	391.0	COG2820@1|root,COG2820@2|Bacteria,1QVR4@1224|Proteobacteria,1T2HJ@1236|Gammaproteobacteria,1X3C6@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile	-	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
WH2_k127_10558359_3	926559.JoomaDRAFT_3262	3.665e-79	286.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1HXIE@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
WH2_k127_10558359_0	926562.Oweho_1295	8.999e-225	721.0	COG1629@1|root,COG4771@2|Bacteria,4PPAD@976|Bacteroidetes	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
WH2_k127_10570200_2	755732.Fluta_2365	1.034e-21	100.0	2C52N@1|root,315JU@2|Bacteria,4PJRQ@976|Bacteroidetes,1IE9T@117743|Flavobacteriia,2PB34@246874|Cryomorphaceae	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
WH2_k127_10570200_0	518766.Rmar_2332	2.524e-69	247.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,1FJ8B@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
WH2_k127_10570200_1	1279009.ADICEAN_01994	5.053e-57	203.0	COG2870@1|root,COG2870@2|Bacteria,4NHUV@976|Bacteroidetes,47K45@768503|Cytophagia	976|Bacteroidetes	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
WH2_k127_10580017_2	760192.Halhy_2539	3.512e-31	128.0	COG1416@1|root,COG1416@2|Bacteria,4NUNC@976|Bacteroidetes,1IUMY@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM DsrE DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
WH2_k127_10580017_0	616991.JPOO01000001_gene4608	1.725e-174	564.0	COG0659@1|root,COG0659@2|Bacteria,4NF1C@976|Bacteroidetes,1HX8C@117743|Flavobacteriia,23H4P@178469|Arenibacter	976|Bacteroidetes	P	STAS domain	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
WH2_k127_10580017_1	468059.AUHA01000005_gene2435	4.118e-36	138.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,1IVAT@117747|Sphingobacteriia	976|Bacteroidetes	F	COGs COG0737 5'-nucleotidase 2' 3'-cyclic phosphodiesterase and related esterase	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
WH2_k127_10589515_0	929556.Solca_4126	2.987e-191	601.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WH2_k127_10589515_1	1356852.N008_16760	2.031e-36	142.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,47QCW@768503|Cytophagia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
WH2_k127_10590570_0	1121898.Q766_17210	2.602e-193	616.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1HX3Y@117743|Flavobacteriia,2NUC3@237|Flavobacterium	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
WH2_k127_10590570_2	1218108.KB908297_gene2973	9.916e-42	167.0	COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,1I1Y4@117743|Flavobacteriia	976|Bacteroidetes	T	Molecular chaperone DnaK	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
WH2_k127_10590570_1	869213.JCM21142_1647	6.389e-66	232.0	COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,47MEJ@768503|Cytophagia	976|Bacteroidetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
WH2_k127_10607329_0	1123277.KB893184_gene4194	4.75e-127	416.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,47PB1@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
WH2_k127_10607329_1	883096.HMPREF9699_00621	2.228e-72	247.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1I29E@117743|Flavobacteriia	976|Bacteroidetes	S	transporter	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WH2_k127_10607329_2	1288963.ADIS_3392	5.68e-40	150.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,47NY1@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WH2_k127_10649767_1	861299.J421_6004	3.909e-16	88.0	COG3279@1|root,COG3279@2|Bacteria,1ZUUN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
WH2_k127_10649767_0	385682.AFSL01000105_gene92	2.64e-34	153.0	COG0457@1|root,COG2972@1|root,COG0457@2|Bacteria,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,2G0ER@200643|Bacteroidia,3XIJ8@558415|Marinilabiliaceae	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,TPR_12,TPR_7,TPR_8
WH2_k127_10649767_2	1961.JOAK01000014_gene5630	0.0009616	50.0	COG0631@1|root,COG0631@2|Bacteria,2GJSB@201174|Actinobacteria	201174|Actinobacteria	T	Protein phosphatase 2C	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
WH2_k127_10654777_3	926550.CLDAP_00380	1.28e-14	74.0	COG0427@1|root,COG0427@2|Bacteria,2G60V@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Acetyl-CoA hydrolase transferase	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
WH2_k127_10654777_0	929556.Solca_4330	3.964e-319	990.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,1INUN@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
WH2_k127_10654777_2	1304883.KI912532_gene1340	1.11e-18	87.0	COG4185@1|root,COG4185@2|Bacteria,1RFDC@1224|Proteobacteria,2VQ41@28216|Betaproteobacteria,2KY6V@206389|Rhodocyclales	206389|Rhodocyclales	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
WH2_k127_10654777_4	398767.Glov_2141	3.484e-12	67.0	COG4185@1|root,COG4185@2|Bacteria,1RFDC@1224|Proteobacteria,42TT0@68525|delta/epsilon subdivisions,2WQEY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
WH2_k127_10654777_5	1492737.FEM08_11500	0.0007487	45.0	2EJQ9@1|root,33DF2@2|Bacteria,4NXTT@976|Bacteroidetes,1I6T9@117743|Flavobacteriia,2NXVU@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10654777_1	886377.Murru_1766	9.872e-39	151.0	COG4914@1|root,COG4914@2|Bacteria,4NPKP@976|Bacteroidetes,1I26C@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
WH2_k127_10676705_3	1185876.BN8_03577	1.294e-16	85.0	COG3291@1|root,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes,47KMB@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
WH2_k127_10676705_2	1122176.KB903556_gene4076	2.071e-51	189.0	29WC5@1|root,30HXS@2|Bacteria,4NNWN@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10676705_1	926562.Oweho_1079	2.76e-70	247.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,1HX9E@117743|Flavobacteriia,2PAUH@246874|Cryomorphaceae	976|Bacteroidetes	M	NlpC/P60 family	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
WH2_k127_10676705_0	700598.Niako_1583	7.941e-108	353.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1IP5F@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	phbA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WH2_k127_10678535_0	1123248.KB893321_gene544	8.229e-148	480.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IW7P@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WH2_k127_10698501_1	1349785.BAUG01000047_gene2323	4.195e-40	153.0	COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,1I2ZX@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
WH2_k127_10698501_0	929556.Solca_0518	2.524e-100	340.0	COG3278@1|root,COG3278@2|Bacteria,4NIGA@976|Bacteroidetes,1IP1A@117747|Sphingobacteriia	976|Bacteroidetes	O	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
WH2_k127_10712633_0	886379.AEWI01000013_gene2163	2.397e-47	171.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,2FMMT@200643|Bacteroidia,3XJPA@558415|Marinilabiliaceae	976|Bacteroidetes	U	SRP54-type protein, helical bundle domain	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
WH2_k127_10712633_1	1519464.HY22_06230	1.489e-17	87.0	2AD7J@1|root,312WH@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
WH2_k127_10712633_3	768706.Desor_5373	2.726e-06	56.0	2DBYH@1|root,2ZBV5@2|Bacteria,1V7E7@1239|Firmicutes,24KWV@186801|Clostridia,2650X@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10712633_2	1121271.AUCM01000001_gene3450	3.827e-10	66.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TYSQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4,PAS_8
WH2_k127_10713215_2	398720.MED217_11419	4.01e-72	244.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1HWTI@117743|Flavobacteriia,2XJ5F@283735|Leeuwenhoekiella	976|Bacteroidetes	E	Tetrahydrodipicolinate N-succinyltransferase N-terminal	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
WH2_k127_10713215_0	929556.Solca_1830	2.938e-128	422.0	COG1253@1|root,COG1253@2|Bacteria,4NE9R@976|Bacteroidetes,1IP76@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	corC_1	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
WH2_k127_10713215_1	925409.KI911562_gene1788	1.788e-100	360.0	COG0859@1|root,COG0859@2|Bacteria,4PKBY@976|Bacteroidetes,1IWTZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WH2_k127_10722250_0	1124780.ANNU01000018_gene1648	1.358e-171	557.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,47JPG@768503|Cytophagia	976|Bacteroidetes	F	TIGRFAM dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
WH2_k127_10722250_2	760192.Halhy_6187	3.735e-97	323.0	COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes,1IRP1@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WH2_k127_10722250_1	1392490.JHZX01000001_gene869	1.15e-100	355.0	COG1361@1|root,COG4886@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,4NG93@976|Bacteroidetes,1HXFW@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
WH2_k127_1072530_1	1304883.KI912532_gene3058	7.281e-12	78.0	28PES@1|root,2ZC68@2|Bacteria,1RBB8@1224|Proteobacteria,2VQV5@28216|Betaproteobacteria,2KWA0@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1072530_0	1358423.N180_05230	2.902e-32	127.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,1INS0@117747|Sphingobacteriia	976|Bacteroidetes	S	of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
WH2_k127_10740542_0	1168034.FH5T_04745	8.603e-175	559.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,2FN63@200643|Bacteroidia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
WH2_k127_10740542_1	1033732.CAHI01000009_gene1690	6.66e-78	267.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,2FN64@200643|Bacteroidia,22U2W@171550|Rikenellaceae	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
WH2_k127_10773730_0	395495.Lcho_4290	1.627e-14	83.0	COG4733@1|root,COG4733@2|Bacteria,1P9NV@1224|Proteobacteria	1224|Proteobacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10774029_1	1356852.N008_08405	4.432e-35	136.0	COG0500@1|root,COG0500@2|Bacteria,4PP98@976|Bacteroidetes,47PJZ@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_31
WH2_k127_10774029_2	742817.HMPREF9449_02791	1.045e-29	123.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,2FT27@200643|Bacteroidia,22YGP@171551|Porphyromonadaceae	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
WH2_k127_10774029_0	1250278.JQNQ01000001_gene474	1.499e-65	237.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1HWWR@117743|Flavobacteriia	976|Bacteroidetes	V	abc transporter (atp-binding protein)	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
WH2_k127_10774461_2	1538644.KO02_19130	3.249e-06	55.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,1IQVN@117747|Sphingobacteriia	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
WH2_k127_10774461_0	886377.Murru_1741	3.097e-26	118.0	28JKT@1|root,2Z9DG@2|Bacteria,4NJJK@976|Bacteroidetes,1HYPI@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
WH2_k127_10774461_1	1408433.JHXV01000022_gene3142	8.34e-26	113.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10782125_0	153721.MYP_17	3.728e-98	328.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,47MN7@768503|Cytophagia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
WH2_k127_10782125_1	984262.SGRA_1047	1.164e-73	257.0	COG0438@1|root,COG0438@2|Bacteria,4NJ6W@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
WH2_k127_10783458_1	1385517.N800_13735	9.631e-57	202.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1X3EG@135614|Xanthomonadales	135614|Xanthomonadales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
WH2_k127_10783458_0	743721.Psesu_0799	2.656e-112	366.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,1X4P6@135614|Xanthomonadales	135614|Xanthomonadales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
WH2_k127_10783458_2	1385517.N800_13725	1.817e-41	158.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,1X7GX@135614|Xanthomonadales	135614|Xanthomonadales	J	RNA-binding protein	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
WH2_k127_10783458_3	1442599.JAAN01000031_gene1346	9.133e-18	89.0	COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,1SD91@1236|Gammaproteobacteria,1X7EH@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
WH2_k127_10787289_0	1123278.KB893554_gene3955	5.815e-57	203.0	COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,47PCM@768503|Cytophagia	976|Bacteroidetes	T	GAF domain-containing protein	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
WH2_k127_10787289_1	1004149.AFOE01000003_gene2235	1.52e-41	174.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1HWU2@117743|Flavobacteriia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
WH2_k127_10796419_4	153721.MYP_3858	1.449e-14	79.0	COG4733@1|root,COG4733@2|Bacteria,4NY26@976|Bacteroidetes	976|Bacteroidetes	S	SPTR Putative	-	-	-	-	-	-	-	-	-	-	-	-	fn3
WH2_k127_10796419_1	266762.HQ36_07885	2.092e-70	256.0	28MU3@1|root,2ZB22@2|Bacteria,4NF8V@976|Bacteroidetes,2FR6Q@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10796419_3	742725.HMPREF9450_00198	9.475e-32	141.0	COG0720@1|root,COG0720@2|Bacteria,4NM8H@976|Bacteroidetes,2FU4Q@200643|Bacteroidia,22UI1@171550|Rikenellaceae	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
WH2_k127_10796419_2	1121957.ATVL01000008_gene4538	5.009e-36	154.0	COG2067@1|root,COG2067@2|Bacteria,4NJB3@976|Bacteroidetes,47JGU@768503|Cytophagia	976|Bacteroidetes	I	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
WH2_k127_10796419_0	1122621.ATZA01000028_gene2581	1.146e-72	255.0	COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,1IRH3@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
WH2_k127_10796419_5	1535422.ND16A_1233	1.464e-13	77.0	2B7EF@1|root,320I7@2|Bacteria,1NDV8@1224|Proteobacteria,1SG78@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_10809736_2	1500281.JQKZ01000004_gene3514	2.069e-28	119.0	COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes,1HYH0@117743|Flavobacteriia,3ZQQT@59732|Chryseobacterium	976|Bacteroidetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WH2_k127_10809736_1	866536.Belba_0630	2.183e-51	192.0	COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes,47P8Z@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
WH2_k127_10809736_0	746697.Aeqsu_0515	2.247e-68	246.0	COG4935@1|root,COG4935@2|Bacteria,4NF3C@976|Bacteroidetes,1HWT9@117743|Flavobacteriia	976|Bacteroidetes	O	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Omp28
WH2_k127_1081402_0	926562.Oweho_1232	2.125e-129	427.0	COG3049@1|root,COG3049@2|Bacteria,4PKMY@976|Bacteroidetes,1IKDD@117743|Flavobacteriia,2PAAJ@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
WH2_k127_1081402_1	1313421.JHBV01000138_gene1212	5.075e-118	401.0	COG1541@1|root,COG1541@2|Bacteria,4NGRR@976|Bacteroidetes,1IP0X@117747|Sphingobacteriia	976|Bacteroidetes	H	AMP-binding enzyme	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
WH2_k127_1081402_3	471854.Dfer_5792	1.425e-23	109.0	2E7GE@1|root,331Z7@2|Bacteria,4NWN3@976|Bacteroidetes,47RY7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1081402_2	926562.Oweho_1781	1.256e-109	369.0	COG0500@1|root,COG2226@2|Bacteria,4NGN8@976|Bacteroidetes,1IK35@117743|Flavobacteriia,2PAH3@246874|Cryomorphaceae	976|Bacteroidetes	H	O-methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
WH2_k127_1081946_1	319795.Dgeo_1637	3.024e-47	173.0	COG0205@1|root,COG0205@2|Bacteria,1WINW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
WH2_k127_1081946_0	700598.Niako_1029	1.891e-186	601.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1IWD6@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WH2_k127_10829648_0	111105.HR09_08950	4.236e-120	401.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,2FN92@200643|Bacteroidia,22WG2@171551|Porphyromonadaceae	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WH2_k127_10829648_1	755732.Fluta_2548	8.472e-07	51.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1HXGH@117743|Flavobacteriia,2PA9N@246874|Cryomorphaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
WH2_k127_1089932_1	471854.Dfer_2171	8.511e-118	400.0	COG2989@1|root,COG2989@2|Bacteria,4NH3J@976|Bacteroidetes,47MU1@768503|Cytophagia	976|Bacteroidetes	T	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
WH2_k127_1089932_3	929562.Emtol_2837	4.99e-45	172.0	COG1376@1|root,COG1376@2|Bacteria,4NNX7@976|Bacteroidetes,47NYB@768503|Cytophagia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
WH2_k127_1089932_0	1519464.HY22_06375	1.712e-123	406.0	COG0438@1|root,COG0438@2|Bacteria,1FDVR@1090|Chlorobi	1090|Chlorobi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH2_k127_1089932_2	1519464.HY22_06390	7.116e-111	363.0	COG0859@1|root,COG0859@2|Bacteria,1FF11@1090|Chlorobi	1090|Chlorobi	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WH2_k127_1094041_4	435591.BDI_0799	1.181e-28	117.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,2FKZZ@200643|Bacteroidia,22WHC@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WH2_k127_1094041_1	385682.AFSL01000056_gene1967	1.554e-58	216.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,2FM3H@200643|Bacteroidia,3XIW8@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase (PrmA)	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
WH2_k127_1094041_0	880074.BARVI_10965	6.107e-90	310.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,2FM4R@200643|Bacteroidia,22WQZ@171551|Porphyromonadaceae	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
WH2_k127_1094041_2	1168034.FH5T_00010	3.731e-37	153.0	COG0697@1|root,COG0697@2|Bacteria,4NGWA@976|Bacteroidetes,2FYPK@200643|Bacteroidia	976|Bacteroidetes	EG	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WH2_k127_1094041_3	1408473.JHXO01000009_gene3357	2.084e-29	132.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,2FQHX@200643|Bacteroidia	976|Bacteroidetes	S	YigZ family	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
WH2_k127_1113453_0	1408433.JHXV01000033_gene1155	2.399e-25	124.0	COG0419@1|root,COG1196@1|root,COG3391@1|root,COG0419@2|Bacteria,COG1196@2|Bacteria,COG3391@2|Bacteria,4PP0U@976|Bacteroidetes,1ICPT@117743|Flavobacteriia,2PBJT@246874|Cryomorphaceae	976|Bacteroidetes	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1134519_1	1124780.ANNU01000028_gene1013	2.376e-11	66.0	COG0491@1|root,COG0491@2|Bacteria,4NE2Y@976|Bacteroidetes,47PA3@768503|Cytophagia	976|Bacteroidetes	P	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WH2_k127_1134519_0	1408433.JHXV01000010_gene496	1.007e-109	370.0	COG4775@1|root,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1I8E9@117743|Flavobacteriia,2PBCC@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM WD40-like beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
WH2_k127_1137359_0	1313421.JHBV01000041_gene3547	2.558e-278	887.0	COG0612@1|root,COG0612@2|Bacteria,4NDXM@976|Bacteroidetes,1IQ0D@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WH2_k127_1141985_3	243233.MCA0713	1.328e-18	100.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,1SCPF@1236|Gammaproteobacteria,1XFSQ@135618|Methylococcales	135618|Methylococcales	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
WH2_k127_1141985_0	1123248.KB893321_gene465	7.365e-223	736.0	COG2133@1|root,COG3291@1|root,COG3391@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,4NF7B@976|Bacteroidetes,1IWJV@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PKD
WH2_k127_1141985_5	159749.K0REE3	5.623e-17	97.0	2E0FN@1|root,2S7W7@2759|Eukaryota,2XFAD@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1141985_1	1123277.KB893191_gene2897	1.567e-44	188.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Peptidase_S74,SprB
WH2_k127_1141985_4	593117.TGAM_0969	2.476e-18	97.0	arCOG02559@1|root,arCOG02559@2157|Archaea,2Y0CM@28890|Euryarchaeota,245E0@183968|Thermococci	183968|Thermococci	S	by modhmm	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PEGA
WH2_k127_1141985_2	1313301.AUGC01000006_gene17	2.027e-22	104.0	COG0671@1|root,COG0671@2|Bacteria,4NV5Q@976|Bacteroidetes	976|Bacteroidetes	I	Pfam PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
WH2_k127_1144657_1	927658.AJUM01000017_gene3118	1.954e-40	157.0	COG1595@1|root,COG1595@2|Bacteria,4NMM3@976|Bacteroidetes,2FNH5@200643|Bacteroidia,3XJ3Z@558415|Marinilabiliaceae	976|Bacteroidetes	K	ECF sigma factor	sigR_3	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH2_k127_1144657_0	1356852.N008_02205	5.096e-141	458.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,47JMY@768503|Cytophagia	976|Bacteroidetes	Q	TIGRFAM phytoene desaturase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
WH2_k127_1144692_0	616991.JPOO01000001_gene4139	1.363e-66	236.0	COG1018@1|root,COG1018@2|Bacteria,4NM4J@976|Bacteroidetes,1I1RH@117743|Flavobacteriia,23HFY@178469|Arenibacter	976|Bacteroidetes	C	FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,FAD_binding_8,NAD_binding_1
WH2_k127_1144692_1	755732.Fluta_1372	9.6e-56	210.0	COG3291@1|root,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes,1IE9N@117743|Flavobacteriia,2PB1T@246874|Cryomorphaceae	976|Bacteroidetes	J	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS,fn3
WH2_k127_1157379_0	984262.SGRA_1328	2.994e-69	248.0	COG2132@1|root,COG3209@1|root,COG2132@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	CHU_C,Copper-bind,Cu-oxidase_3,PKD,SprB
WH2_k127_1158282_1	266748.HY04_11265	3.392e-72	252.0	COG0589@1|root,COG0589@2|Bacteria,4PM0T@976|Bacteroidetes,1IJIJ@117743|Flavobacteriia	976|Bacteroidetes	T	response to stress	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WH2_k127_1158282_0	760192.Halhy_4982	3.402e-244	766.0	COG3263@1|root,COG3263@2|Bacteria,4NFNS@976|Bacteroidetes,1IX7C@117747|Sphingobacteriia	976|Bacteroidetes	P	TrkA-C domain	cvrA	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
WH2_k127_1164046_0	1237149.C900_00766	7.716e-59	222.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
WH2_k127_1165745_0	1237149.C900_03366	6.751e-240	748.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,47MI5@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
WH2_k127_1165745_2	1279009.ADICEAN_00450	5.887e-11	65.0	COG3197@1|root,COG3197@2|Bacteria,4NUR7@976|Bacteroidetes,47SPA@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM cytochrome oxidase maturation protein, cbb3-type	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
WH2_k127_1165745_1	1124780.ANNU01000013_gene3847	4.649e-30	122.0	COG2217@1|root,COG2217@2|Bacteria,4NEI1@976|Bacteroidetes,47N4X@768503|Cytophagia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
WH2_k127_116833_1	1463920.JOGB01000021_gene2053	5.46e-06	48.0	COG4912@1|root,COG4912@2|Bacteria,2GNQD@201174|Actinobacteria	201174|Actinobacteria	L	DNA alkylation repair	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
WH2_k127_116833_0	762903.Pedsa_2481	7.515e-147	479.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1IQEP@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
WH2_k127_1169318_2	1131553.JIBI01000032_gene2295	3.017e-42	168.0	29QU6@1|root,30BU6@2|Bacteria,1NKTK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1169318_0	1189620.AJXL01000043_gene623	6.897e-60	215.0	COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,1HX2T@117743|Flavobacteriia,2NTWM@237|Flavobacterium	976|Bacteroidetes	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
WH2_k127_1169318_3	595537.Varpa_1002	6.153e-40	158.0	COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,2VTR4@28216|Betaproteobacteria,4AEDJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
WH2_k127_1169318_4	1318628.MARLIPOL_13149	5.027e-38	147.0	COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria,467AU@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Zn-ribbon-containing protein involved in phosphonate metabolism	phnA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
WH2_k127_1169318_1	1122176.KB903542_gene405	4.922e-46	171.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WH2_k127_1169318_5	1197477.IA57_02120	5.468e-33	133.0	2DM8U@1|root,3273Z@2|Bacteria,4NQC2@976|Bacteroidetes,1I2Y5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1172055_1	1237149.C900_05934	8.479e-19	89.0	COG3209@1|root,COG3291@1|root,COG3405@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3405@2|Bacteria,4NDZC@976|Bacteroidetes,47MNQ@768503|Cytophagia	976|Bacteroidetes	O	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
WH2_k127_1172055_0	1120999.JONM01000016_gene202	5.386e-36	146.0	COG2153@1|root,COG2153@2|Bacteria,1MZHA@1224|Proteobacteria,2VTYH@28216|Betaproteobacteria,2KRIJ@206351|Neisseriales	206351|Neisseriales	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
WH2_k127_1172055_2	1123234.AUKI01000002_gene1801	5.308e-16	88.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
WH2_k127_1187814_2	700598.Niako_2936	6.681e-33	135.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	Methyltransf_23,Methyltransf_25
WH2_k127_1187814_0	153721.MYP_1005	1.23e-117	383.0	COG3751@1|root,COG3751@2|Bacteria,4NI8F@976|Bacteroidetes,47QQK@768503|Cytophagia	976|Bacteroidetes	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
WH2_k127_1187814_1	1453500.AT05_04790	3.878e-33	131.0	COG4122@1|root,COG4122@2|Bacteria,4NZ83@976|Bacteroidetes,1IB7E@117743|Flavobacteriia	976|Bacteroidetes	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
WH2_k127_1187814_3	1322246.BN4_20260	1.922e-07	56.0	COG0457@1|root,COG0457@2|Bacteria,1R1BU@1224|Proteobacteria,43D8I@68525|delta/epsilon subdivisions,2X8F5@28221|Deltaproteobacteria,2MB0J@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
WH2_k127_1201165_0	1191523.MROS_1166	2.164e-91	322.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
WH2_k127_1201165_1	195250.CM001776_gene2903	5.786e-09	59.0	COG0729@1|root,COG0729@2|Bacteria,1GDRV@1117|Cyanobacteria	1117|Cyanobacteria	M	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1228394_0	313596.RB2501_02575	1.111e-190	611.0	COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,1HWJU@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
WH2_k127_1228394_2	1123248.KB893348_gene266	7.215e-46	185.0	COG0642@1|root,COG2205@2|Bacteria,4NK58@976|Bacteroidetes,1IPNM@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WH2_k127_1228394_1	760192.Halhy_3315	3.651e-49	196.0	COG1418@1|root,COG1418@2|Bacteria,4NFAG@976|Bacteroidetes,1ISTR@117747|Sphingobacteriia	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HD
WH2_k127_1228394_3	745718.JADT01000002_gene2430	1.14e-07	55.0	2DR32@1|root,339YJ@2|Bacteria,4NYM3@976|Bacteroidetes,1I6CH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1246766_2	679937.Bcop_2418	1.432e-53	192.0	COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes,2G0DF@200643|Bacteroidia,4AVEK@815|Bacteroidaceae	976|Bacteroidetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
WH2_k127_1246766_1	1286632.P278_10940	1.11e-144	467.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,1HXZY@117743|Flavobacteriia	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WH2_k127_1246766_0	755732.Fluta_0180	2.109e-186	596.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1HWJC@117743|Flavobacteriia,2PAHS@246874|Cryomorphaceae	976|Bacteroidetes	J	Ribonuclease E/G family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
WH2_k127_1260605_1	1408433.JHXV01000008_gene221	7.993e-22	103.0	COG1807@1|root,COG1807@2|Bacteria,4NXNF@976|Bacteroidetes,1IMQ5@117743|Flavobacteriia,2PB6F@246874|Cryomorphaceae	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1260605_0	1122176.KB903565_gene3367	2.302e-117	381.0	COG1788@1|root,COG1788@2|Bacteria,4NF3T@976|Bacteroidetes,1IQP0@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoA	-	2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01031,ko:K01034	ko00072,ko00280,ko00310,ko00362,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00362,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R02990,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WH2_k127_1260605_2	755732.Fluta_1343	4.202e-09	59.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HXWX@117743|Flavobacteriia,2PAGV@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Penicillin binding protein transpeptidase domain	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
WH2_k127_127311_3	1408433.JHXV01000039_gene2184	1.805e-26	111.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,1HYTK@117743|Flavobacteriia,2PB8R@246874|Cryomorphaceae	976|Bacteroidetes	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
WH2_k127_127311_4	1124780.ANNU01000055_gene3444	7.407e-18	91.0	COG3209@1|root,COG3209@2|Bacteria,4NF0G@976|Bacteroidetes,47XBH@768503|Cytophagia	976|Bacteroidetes	M	Salmonella virulence plasmid 65kDa B protein	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN
WH2_k127_127311_6	1123035.ARLA01000025_gene1327	1.449e-05	54.0	2A3X0@1|root,30SFB@2|Bacteria,4PHBC@976|Bacteroidetes,1IFUU@117743|Flavobacteriia,4C4GG@83612|Psychroflexus	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_127311_1	1210884.HG799474_gene15174	2.218e-63	226.0	COG0730@1|root,COG0730@2|Bacteria,2J37C@203682|Planctomycetes	203682|Planctomycetes	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
WH2_k127_127311_0	1313301.AUGC01000001_gene1411	5.23e-256	797.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WH2_k127_127311_2	700598.Niako_2735	2.038e-29	134.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG3850@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3850@2|Bacteria,4NFBM@976|Bacteroidetes,1IQZ6@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,Response_reg
WH2_k127_127311_5	1047013.AQSP01000070_gene34	3.116e-11	76.0	COG3292@1|root,COG3920@1|root,COG3292@2|Bacteria,COG3920@2|Bacteria,2NNZT@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	pdtaS	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2,Reg_prop,Y_Y_Y
WH2_k127_1293294_2	714943.Mucpa_2855	2.524e-28	128.0	COG0670@1|root,COG0670@2|Bacteria,4NR2U@976|Bacteroidetes,1ISUF@117747|Sphingobacteriia	976|Bacteroidetes	S	Inhibitor of apoptosis-promoting Bax1	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
WH2_k127_1293294_0	1358423.N180_16765	2.72e-96	319.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1IPBD@117747|Sphingobacteriia	976|Bacteroidetes	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
WH2_k127_1293294_1	1408813.AYMG01000001_gene3724	7.899e-53	189.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1IXEM@117747|Sphingobacteriia	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
WH2_k127_1300957_0	700598.Niako_5661	1.32e-69	255.0	2DBC9@1|root,2Z8CA@2|Bacteria,4NJS4@976|Bacteroidetes,1IPPV@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173
WH2_k127_1300957_1	66897.DJ64_13370	1.345e-39	153.0	2AQME@1|root,31FUG@2|Bacteria,2GJ2E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1300957_2	1279009.ADICEAN_03422	9.439e-20	101.0	COG3021@1|root,COG3021@2|Bacteria,4NGD4@976|Bacteroidetes,47PAD@768503|Cytophagia	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
WH2_k127_1327661_0	1121889.AUDM01000014_gene1970	3.167e-100	368.0	COG3227@1|root,COG3291@1|root,COG3391@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,4NJHV@976|Bacteroidetes,1IMXD@117743|Flavobacteriia,2NV4Y@237|Flavobacterium	976|Bacteroidetes	O	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
WH2_k127_1327661_3	485918.Cpin_1738	1.502e-06	63.0	COG3291@1|root,COG3291@2|Bacteria,4NJQN@976|Bacteroidetes,1IXWG@117747|Sphingobacteriia	976|Bacteroidetes	M	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,IgGFc_binding,PKD,SprB,fn3
WH2_k127_1327661_2	1121896.JMLU01000003_gene2194	2.574e-14	88.0	COG1357@1|root,COG3291@1|root,COG4935@1|root,COG1357@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZC@976|Bacteroidetes,1I0G4@117743|Flavobacteriia,2NT7Y@237|Flavobacterium	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CHU_C,He_PIG,fn3
WH2_k127_1327661_4	1120951.AUBG01000022_gene1739	1.355e-05	59.0	COG3227@1|root,COG4733@1|root,COG3227@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,NPCBM,Phage-tail_3,Trypsin_2,fn3
WH2_k127_1348841_3	1237149.C900_04062	4.362e-06	57.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes	976|Bacteroidetes	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WH2_k127_1348841_0	984262.SGRA_3844	1.401e-98	327.0	COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,1IPQ0@117747|Sphingobacteriia	976|Bacteroidetes	O	AhpC TSA family	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
WH2_k127_1348841_1	755732.Fluta_1672	1.874e-12	74.0	COG2885@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,4NKCW@976|Bacteroidetes,1HXSH@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM Outer membrane protein, OmpA MotB, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
WH2_k127_1356626_0	926569.ANT_06550	1.386e-29	135.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
WH2_k127_1436406_1	1379270.AUXF01000001_gene2228	6.178e-58	207.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
WH2_k127_1436406_2	1166018.FAES_3690	6.889e-46	171.0	COG2128@1|root,COG2128@2|Bacteria,4NHD5@976|Bacteroidetes,47M83@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
WH2_k127_1436406_3	706587.Desti_4837	0.0004873	52.0	COG2755@1|root,COG2755@2|Bacteria,1R1JV@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1436406_0	388413.ALPR1_03795	9.212e-86	289.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,47K3J@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WH2_k127_1471559_2	1123248.KB893386_gene1850	1.054e-41	156.0	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,1IT8P@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
WH2_k127_1471559_0	997829.HMPREF1121_00758	2.749e-73	254.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,2FN8Z@200643|Bacteroidia,22WBB@171551|Porphyromonadaceae	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
WH2_k127_1471559_1	485918.Cpin_0710	8.306e-68	244.0	COG0707@1|root,COG0707@2|Bacteria,4NFRJ@976|Bacteroidetes,1IX57@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
WH2_k127_1477981_1	742817.HMPREF9449_01584	1.21e-35	146.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,2FN2K@200643|Bacteroidia,22W1X@171551|Porphyromonadaceae	976|Bacteroidetes	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
WH2_k127_1477981_2	485918.Cpin_1516	2.33e-06	58.0	COG3827@1|root,COG3827@2|Bacteria,4PKT6@976|Bacteroidetes,1J0M3@117747|Sphingobacteriia	976|Bacteroidetes	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1477981_0	1124780.ANNU01000056_gene3468	2.646e-71	256.0	COG2234@1|root,COG2234@2|Bacteria,4NGPJ@976|Bacteroidetes,47NIK@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WH2_k127_1480175_3	1121889.AUDM01000003_gene2250	1.933e-20	90.0	COG0428@1|root,COG0428@2|Bacteria,4NGQ8@976|Bacteroidetes,1HXM3@117743|Flavobacteriia,2NV5S@237|Flavobacterium	976|Bacteroidetes	P	ZIP Zinc transporter	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
WH2_k127_1480175_0	935863.AWZR01000001_gene1706	2.566e-63	233.0	COG1819@1|root,COG1819@2|Bacteria,1MVI7@1224|Proteobacteria,1S57B@1236|Gammaproteobacteria,1X5IY@135614|Xanthomonadales	135614|Xanthomonadales	CG	Glycosyl transferases, related to UDP-glucuronosyltransferase	ugt	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
WH2_k127_1480175_4	1216967.L100_02537	8.146e-15	81.0	2C56J@1|root,31HT2@2|Bacteria,4NQZE@976|Bacteroidetes,1IGSV@117743|Flavobacteriia,34S9R@308865|Elizabethkingia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1480175_1	1056512.D515_04505	5.951e-39	156.0	2DMF7@1|root,32R46@2|Bacteria,1RJFH@1224|Proteobacteria,1S8DC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative papain-like cysteine peptidase (DUF1796)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1796
WH2_k127_1480175_2	1123248.KB893359_gene2046	1.306e-34	141.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,1IPK5@117747|Sphingobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
WH2_k127_1496242_0	1107311.Q767_01615	1.752e-79	293.0	COG1520@1|root,COG3291@1|root,COG3386@1|root,COG5306@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5306@2|Bacteria,4NNUN@976|Bacteroidetes,1IKME@117743|Flavobacteriia,2NXAD@237|Flavobacterium	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,SBBP
WH2_k127_1496242_1	866536.Belba_0485	2.966e-40	161.0	COG3279@1|root,COG3279@2|Bacteria,4NF8A@976|Bacteroidetes,47QFV@768503|Cytophagia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
WH2_k127_1496242_3	1122179.KB890480_gene3139	1.266e-21	100.0	COG3920@1|root,COG3920@2|Bacteria,4NINT@976|Bacteroidetes	976|Bacteroidetes	T	Pfam Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,HisKA_2,TPR_12
WH2_k127_150333_3	755732.Fluta_2550	1.151e-17	83.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1HYJD@117743|Flavobacteriia,2PAHV@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
WH2_k127_150333_0	468059.AUHA01000002_gene1106	4.23e-115	384.0	COG2067@1|root,COG2067@2|Bacteria,4NDZW@976|Bacteroidetes,1IPX7@117747|Sphingobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	porV	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_150333_1	153721.MYP_1243	3.552e-60	222.0	COG0245@1|root,COG0245@2|Bacteria,4NP0N@976|Bacteroidetes,47PDR@768503|Cytophagia	976|Bacteroidetes	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
WH2_k127_150333_2	1313421.JHBV01000020_gene5204	1.477e-24	107.0	arCOG14808@1|root,308PC@2|Bacteria,4NR4D@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
WH2_k127_1516248_0	1408433.JHXV01000015_gene1790	2.432e-17	96.0	28NPZ@1|root,2ZBPQ@2|Bacteria,4PFIJ@976|Bacteroidetes,1IB9Q@117743|Flavobacteriia,2PBWA@246874|Cryomorphaceae	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
WH2_k127_1522402_0	1237149.C900_05190	6.606e-216	691.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,47JNI@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
WH2_k127_1535846_0	1121957.ATVL01000007_gene1966	7.365e-190	619.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,47KXK@768503|Cytophagia	976|Bacteroidetes	G	PFAM GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WH2_k127_1539080_2	714943.Mucpa_5342	1.604e-33	131.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1IQ4U@117747|Sphingobacteriia	976|Bacteroidetes	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
WH2_k127_1539080_1	553175.POREN0001_1794	2.753e-90	314.0	COG0438@1|root,COG0438@2|Bacteria,4NFMB@976|Bacteroidetes,2FMJE@200643|Bacteroidia,22XBH@171551|Porphyromonadaceae	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
WH2_k127_1539080_0	694427.Palpr_1191	9.743e-107	360.0	COG0438@1|root,COG0438@2|Bacteria,4NH7K@976|Bacteroidetes,2FSCQ@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WH2_k127_1545265_0	1120965.AUBV01000014_gene1159	1.074e-156	503.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
WH2_k127_1545265_3	1237149.C900_03250	1.931e-25	113.0	2CKAK@1|root,32SBZ@2|Bacteria,4NSJ2@976|Bacteroidetes,47RYW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1545265_2	1118060.CAGZ01000005_gene1638	2.136e-41	158.0	COG1051@1|root,COG3727@1|root,COG1051@2|Bacteria,COG3727@2|Bacteria,2IKPY@201174|Actinobacteria,4CV6Q@84998|Coriobacteriia	84998|Coriobacteriia	L	DNA mismatch endonuclease vsr	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,Vsr
WH2_k127_1545265_1	1313421.JHBV01000014_gene3970	2.962e-127	421.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
WH2_k127_1546986_0	926562.Oweho_0625	1.497e-118	396.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1HY9Q@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WH2_k127_1546986_1	926562.Oweho_0624	1.532e-27	119.0	COG2272@1|root,COG2272@2|Bacteria,4PI06@976|Bacteroidetes,1IG13@117743|Flavobacteriia,2PB7F@246874|Cryomorphaceae	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	COesterase
WH2_k127_1554032_2	870187.Thini_1169	2.357e-27	128.0	COG0589@1|root,COG0589@2|Bacteria,1N5Z8@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WH2_k127_1554032_3	700598.Niako_5416	1.872e-06	49.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IW8Y@117747|Sphingobacteriia	976|Bacteroidetes	L	resolvase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WH2_k127_1554032_0	1279009.ADICEAN_01262	1.393e-76	266.0	COG3001@1|root,COG3001@2|Bacteria,4NEQY@976|Bacteroidetes,47K5K@768503|Cytophagia	976|Bacteroidetes	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
WH2_k127_1554032_1	1122176.KB903587_gene4492	1.288e-64	243.0	COG1520@1|root,COG1520@2|Bacteria,4NMP7@976|Bacteroidetes	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
WH2_k127_1562255_0	1121106.JQKB01000002_gene3407	1.085e-108	362.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,2U0DX@28211|Alphaproteobacteria,2JV97@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH2_k127_1562255_1	1382356.JQMP01000003_gene2572	1.275e-26	116.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi,27Y1R@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH2_k127_1582989_1	1392490.JHZX01000001_gene1039	2.288e-15	78.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	-	-	3.1.21.3	ko:K01154,ko:K07461	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	GIY-YIG
WH2_k127_1582989_0	1279009.ADICEAN_03460	1.058e-58	217.0	COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,47KRS@768503|Cytophagia	976|Bacteroidetes	E	Alanine dehydrogenase PNT, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
WH2_k127_1593169_1	761193.Runsl_1176	2.649e-70	244.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,47K9F@768503|Cytophagia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
WH2_k127_1593169_3	760192.Halhy_4506	8.42e-11	72.0	2ETUA@1|root,33MBM@2|Bacteria,4PJ6R@976|Bacteroidetes,1IZNY@117747|Sphingobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
WH2_k127_1593169_2	388413.ALPR1_12565	4.579e-22	105.0	2EUZ3@1|root,33NEA@2|Bacteria,4NYVA@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1593169_0	700598.Niako_6871	9.681e-114	378.0	COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,1IVXW@117747|Sphingobacteriia	976|Bacteroidetes	E	Tryptophan 2,3-dioxygenase	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
WH2_k127_1600850_2	1121899.Q764_07530	3.542e-51	188.0	COG2335@1|root,COG2335@2|Bacteria,4NMPI@976|Bacteroidetes,1I1DK@117743|Flavobacteriia,2P06C@237|Flavobacterium	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
WH2_k127_1600850_4	1268622.AVS7_04003	5.901e-33	143.0	arCOG14922@1|root,32SW8@2|Bacteria,1N0NY@1224|Proteobacteria,2VV7B@28216|Betaproteobacteria,4AF7R@80864|Comamonadaceae	28216|Betaproteobacteria	S	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
WH2_k127_1600850_1	1089547.KB913013_gene4638	1.088e-53	203.0	COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,47KSX@768503|Cytophagia	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_5
WH2_k127_1600850_0	468059.AUHA01000007_gene2675	1.843e-58	211.0	COG1131@1|root,COG1131@2|Bacteria,4NG9T@976|Bacteroidetes,1IPBT@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K19340	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC_tran
WH2_k127_1600850_3	471854.Dfer_0695	2.971e-39	149.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,47KEF@768503|Cytophagia	976|Bacteroidetes	P	Periplasmic copper-binding protein (NosD)	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
WH2_k127_1614156_1	926550.CLDAP_06400	1.01e-10	65.0	COG3383@1|root,COG3383@2|Bacteria,2GBH3@200795|Chloroflexi	200795|Chloroflexi	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WH2_k127_1614156_2	314230.DSM3645_05735	1.636e-08	67.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,2IY4U@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
WH2_k127_1614156_0	1341155.FSS13T_13880	2.391e-16	92.0	COG1361@1|root,COG3291@1|root,COG3391@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,fn3
WH2_k127_1629730_1	143224.JQMD01000002_gene2008	3.978e-53	197.0	COG0457@1|root,COG2972@1|root,COG0457@2|Bacteria,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,1HXAW@117743|Flavobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,TPR_12,TPR_7,TPR_8
WH2_k127_1629730_0	1121899.Q764_08240	3.53e-57	208.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1HXX5@117743|Flavobacteriia,2NS90@237|Flavobacterium	976|Bacteroidetes	T	Two-component system response regulatory protein, LytTR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
WH2_k127_1631120_2	1267005.KB911255_gene2481	1.782e-31	124.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,3N8FK@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WH2_k127_1631120_0	485917.Phep_0752	4.728e-62	222.0	28K10@1|root,2Z9QW@2|Bacteria,4NF8J@976|Bacteroidetes,1ISKT@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4918
WH2_k127_1631120_1	643867.Ftrac_1341	7.583e-60	213.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,47KD4@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
WH2_k127_1633710_3	743722.Sph21_1608	1.259e-14	78.0	COG0532@1|root,COG3115@1|root,COG0532@2|Bacteria,COG3115@2|Bacteria,4NGP3@976|Bacteroidetes,1IQ0V@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
WH2_k127_1633710_0	1408433.JHXV01000014_gene3647	1.917e-192	607.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,1HY37@117743|Flavobacteriia,2PAGI@246874|Cryomorphaceae	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
WH2_k127_1633710_2	742767.HMPREF9456_02020	3.547e-22	102.0	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,2FSM9@200643|Bacteroidia,22Y41@171551|Porphyromonadaceae	976|Bacteroidetes	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
WH2_k127_1633710_1	926562.Oweho_2096	1.221e-107	355.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1HWWR@117743|Flavobacteriia,2PAGR@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase and permease	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
WH2_k127_1642037_0	1089547.KB913013_gene4561	4.051e-43	173.0	COG1404@1|root,COG3209@1|root,COG3391@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,4NPFV@976|Bacteroidetes	976|Bacteroidetes	MO	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1642037_1	1107311.Q767_14160	1.007e-11	72.0	COG3386@1|root,COG5492@1|root,COG3386@2|Bacteria,COG5492@2|Bacteria,4PPH0@976|Bacteroidetes,1IKMS@117743|Flavobacteriia,2P0SH@237|Flavobacterium	976|Bacteroidetes	G	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
WH2_k127_164724_2	926562.Oweho_1029	6.931e-51	192.0	28H6U@1|root,2Z7J5@2|Bacteria,4NHUU@976|Bacteroidetes,1I8FZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_164724_0	1127696.HMPREF9134_01626	5.349e-67	241.0	COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,2FMSI@200643|Bacteroidia,22X8Y@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
WH2_k127_164724_1	1313421.JHBV01000039_gene2729	5.993e-65	241.0	COG3209@1|root,COG3291@1|root,COG4935@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NHWG@976|Bacteroidetes,1IRF4@117747|Sphingobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
WH2_k127_1664606_0	1408433.JHXV01000029_gene3073	4.422e-285	932.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IMQK@117743|Flavobacteriia,2PBES@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
WH2_k127_1678867_2	1408433.JHXV01000008_gene113	5.308e-57	209.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWWK@117743|Flavobacteriia,2PA7T@246874|Cryomorphaceae	976|Bacteroidetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WH2_k127_1678867_0	1408433.JHXV01000008_gene114	2.444e-82	287.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1HXCA@117743|Flavobacteriia,2PAN8@246874|Cryomorphaceae	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Y_Y_Y
WH2_k127_1678867_3	1137281.D778_00609	6.595e-34	137.0	COG5592@1|root,COG5592@2|Bacteria,4NP8M@976|Bacteroidetes,1I24Y@117743|Flavobacteriia	976|Bacteroidetes	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
WH2_k127_1678867_1	1416760.AYMS01000014_gene453	2.613e-67	232.0	COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,1HXS5@117743|Flavobacteriia,47H9Z@76831|Myroides	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	ric	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
WH2_k127_1707170_1	697282.Mettu_4065	4.758e-20	103.0	2E373@1|root,32ZYW@2|Bacteria,1P98F@1224|Proteobacteria,1SW8T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1707170_0	760192.Halhy_1414	1.11e-65	241.0	COG2114@1|root,COG2114@2|Bacteria,4NG5A@976|Bacteroidetes,1IT6K@117747|Sphingobacteriia	976|Bacteroidetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
WH2_k127_1737423_0	1408473.JHXO01000001_gene2295	1.016e-217	694.0	COG4797@1|root,COG4797@2|Bacteria,4PKQS@976|Bacteroidetes,2FP69@200643|Bacteroidia	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
WH2_k127_1738707_1	746697.Aeqsu_1674	2.596e-27	114.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,1HXNK@117743|Flavobacteriia	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_8
WH2_k127_1738707_2	1123276.KB893279_gene2061	6.695e-20	91.0	COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,47S1U@768503|Cytophagia	976|Bacteroidetes	C	PFAM ATP synthase, Delta Epsilon chain, beta-sandwich domain	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
WH2_k127_1738707_0	1453500.AT05_07745	6.074e-192	602.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1HWM2@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
WH2_k127_1747852_1	1150600.ADIARSV_1842	8.181e-94	317.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1IQCR@117747|Sphingobacteriia	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
WH2_k127_1747852_2	926562.Oweho_2093	5.734e-07	61.0	COG3291@1|root,COG3291@2|Bacteria,4NI4A@976|Bacteroidetes,1I0P7@117743|Flavobacteriia,2PBKJ@246874|Cryomorphaceae	976|Bacteroidetes	O	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Cleaved_Adhesin,MAM,PKD,fn3
WH2_k127_1747852_0	525257.HMPREF0204_14584	6.992e-104	347.0	COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,1HXFB@117743|Flavobacteriia,3ZP3J@59732|Chryseobacterium	976|Bacteroidetes	E	Glycosylasparaginase	aspG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
WH2_k127_1764585_1	1121904.ARBP01000003_gene6407	2.803e-07	58.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
WH2_k127_1764585_0	869213.JCM21142_41900	2.445e-36	153.0	COG0823@1|root,COG2885@1|root,COG3291@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,COG3291@2|Bacteria,4NE6G@976|Bacteroidetes,47K1N@768503|Cytophagia	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,PKD
WH2_k127_1767663_2	1386089.N865_10580	1.205e-10	74.0	COG3227@1|root,COG3227@2|Bacteria,2GN0P@201174|Actinobacteria,4FEV0@85021|Intrasporangiaceae	201174|Actinobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M36,Peptidase_M4_C
WH2_k127_1767663_3	35754.JNYJ01000002_gene6759	0.0009129	52.0	COG2866@1|root,COG2866@2|Bacteria,2GN49@201174|Actinobacteria,4DAA1@85008|Micromonosporales	201174|Actinobacteria	M	Peptidase M14, carboxypeptidase A	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Peptidase_M14
WH2_k127_1767663_0	1137281.D778_02491	1.797e-51	198.0	COG3931@1|root,COG3931@2|Bacteria,4NMA3@976|Bacteroidetes,1I1FX@117743|Flavobacteriia	976|Bacteroidetes	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
WH2_k127_1767663_1	1124780.ANNU01000002_gene1604	2.372e-42	160.0	COG2170@1|root,COG2170@2|Bacteria,4NGA3@976|Bacteroidetes,47U1A@768503|Cytophagia	976|Bacteroidetes	S	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
WH2_k127_180764_1	886379.AEWI01000016_gene1520	4.901e-106	355.0	COG2374@1|root,COG2374@2|Bacteria,4NEHG@976|Bacteroidetes,2FNH4@200643|Bacteroidia,3XINX@558415|Marinilabiliaceae	976|Bacteroidetes	S	Endonuclease exonuclease phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
WH2_k127_180764_4	880073.Calab_3627	1.661e-40	170.0	COG2374@1|root,COG2911@1|root,COG3386@1|root,COG2374@2|Bacteria,COG2911@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	gnl	GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689	1.15.1.1,2.7.11.1,3.1.1.17,3.1.1.2,3.1.3.8,3.1.8.1,3.2.1.4,4.3.3.2	ko:K01045,ko:K01053,ko:K01083,ko:K01179,ko:K01757,ko:K02057,ko:K04565,ko:K08884,ko:K13735	ko00030,ko00053,ko00500,ko00562,ko00901,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko04146,ko04213,ko05014,ko05016,ko05020,ko05100,map00030,map00053,map00500,map00562,map00901,map00930,map01100,map01110,map01120,map01130,map01200,map01220,map04146,map04213,map05014,map05016,map05020,map05100	M00129,M00221	R01519,R02933,R03371,R03738,R03751,R06200,R11307,R11308	RC00078,RC00537,RC00983,RC01072,RC01568	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko04147	3.A.1.2	GH5,GH9	-	SGL,Str_synth
WH2_k127_180764_3	925409.KI911562_gene1557	2.007e-43	179.0	COG2374@1|root,COG4085@1|root,COG2374@2|Bacteria,COG4085@2|Bacteria,4NIB0@976|Bacteroidetes	976|Bacteroidetes	F	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5017,LTD
WH2_k127_180764_0	760192.Halhy_5161	2.33e-222	719.0	COG1629@1|root,COG1629@2|Bacteria,4NFW1@976|Bacteroidetes,1IQ77@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
WH2_k127_180764_2	1313421.JHBV01000019_gene5329	5.831e-64	242.0	COG2132@1|root,COG4935@1|root,COG2132@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	CHU_C,Copper-bind,Cu-oxidase_3,SprB
WH2_k127_1813356_0	391596.PBAL39_08135	1.785e-107	355.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1IQFU@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
WH2_k127_1813356_1	1211115.ALIQ01000183_gene2930	6.691e-15	87.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2TTXG@28211|Alphaproteobacteria,3NAG3@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
WH2_k127_1825841_2	1313301.AUGC01000010_gene982	1.29e-72	255.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes	976|Bacteroidetes	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	LAB_N,PMT,PMT_2
WH2_k127_1825841_0	755732.Fluta_0821	3.9e-108	365.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,1HZ71@117743|Flavobacteriia,2PBGE@246874|Cryomorphaceae	976|Bacteroidetes	T	GHKL domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
WH2_k127_1825841_1	313606.M23134_03355	1.115e-75	264.0	COG0745@1|root,COG0745@2|Bacteria,4NM5Q@976|Bacteroidetes,47PED@768503|Cytophagia	976|Bacteroidetes	K	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WH2_k127_1836207_3	1123257.AUFV01000002_gene2572	4.721e-15	77.0	COG1853@1|root,COG1853@2|Bacteria,1NB1B@1224|Proteobacteria,1S55P@1236|Gammaproteobacteria,1X6AK@135614|Xanthomonadales	135614|Xanthomonadales	S	flavin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
WH2_k127_1836207_4	376686.Fjoh_1339	8.347e-13	74.0	2CJ7C@1|root,32ZYU@2|Bacteria,4NUT6@976|Bacteroidetes,1I538@117743|Flavobacteriia,2NV0V@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1836207_1	315730.BcerKBAB4_4752	7.797e-19	94.0	COG1683@1|root,COG1683@2|Bacteria,1V700@1239|Firmicutes,4HJH0@91061|Bacilli,1ZGEW@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF523)	-	-	-	-	-	-	-	-	-	-	-	-	DUF523
WH2_k127_1836207_2	1208323.B30_15696	1.471e-16	81.0	2EJ6Q@1|root,33CXX@2|Bacteria,1NGPE@1224|Proteobacteria,2UJNQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1836207_0	1121926.AXWO01000001_gene3728	3.839e-32	126.0	COG1193@1|root,COG1193@2|Bacteria,2I4QA@201174|Actinobacteria,4EYUQ@85014|Glycomycetales	201174|Actinobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
WH2_k127_1836207_5	1121381.JNIV01000119_gene3684	1.7e-06	50.0	COG2521@1|root,COG2521@2|Bacteria	2|Bacteria	AJ	methyltransferase	-	-	2.1.1.113,2.1.1.72	ko:K00590,ko:K07319	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methyltransf_11,N6_N4_Mtase
WH2_k127_1837889_1	1538644.KO02_05685	8.598e-108	355.0	COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,1IQ7C@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
WH2_k127_1837889_3	1453500.AT05_05540	3.136e-62	230.0	COG0647@1|root,COG0647@2|Bacteria,4NNYH@976|Bacteroidetes,1I2FP@117743|Flavobacteriia	976|Bacteroidetes	G	Phosphoheptose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_1837889_0	1121898.Q766_00095	1.119e-134	433.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,1HXAY@117743|Flavobacteriia,2NTES@237|Flavobacterium	976|Bacteroidetes	C	CoB--CoM heterodisulfide reductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG
WH2_k127_1837889_4	926550.CLDAP_20200	6.054e-31	131.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WH2_k127_1837889_2	980584.AFPB01000062_gene3316	1.673e-81	273.0	COG0793@1|root,COG0793@2|Bacteria,4PMDZ@976|Bacteroidetes,1IK9R@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
WH2_k127_1850041_0	269798.CHU_2494	1.409e-93	331.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47MEM@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
WH2_k127_1865844_1	592029.DDD_0045	6.493e-41	169.0	COG4886@1|root,COG4935@1|root,COG4886@2|Bacteria,COG4935@2|Bacteria,4NIM6@976|Bacteroidetes,1HX50@117743|Flavobacteriia,3HJ95@363408|Nonlabens	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	fn3
WH2_k127_1865844_2	700598.Niako_1469	3.64e-06	58.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IUVN@117747|Sphingobacteriia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WH2_k127_1865844_0	1279009.ADICEAN_01296	2.104e-132	431.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,47JHX@768503|Cytophagia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WH2_k127_187395_5	1237149.C900_00151	2.406e-12	75.0	COG0642@1|root,COG2205@2|Bacteria	1237149.C900_00151|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_187395_0	1185876.BN8_05365	1.968e-118	398.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47NBF@768503|Cytophagia	976|Bacteroidetes	S	PFAM peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
WH2_k127_187395_2	313596.RB2501_05165	5.329e-65	226.0	COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,1HY16@117743|Flavobacteriia	976|Bacteroidetes	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
WH2_k127_187395_1	742725.HMPREF9450_01042	8.494e-71	244.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,2FN36@200643|Bacteroidia,22UDM@171550|Rikenellaceae	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
WH2_k127_187395_3	1168034.FH5T_14160	1.928e-41	160.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,2FN3J@200643|Bacteroidia	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
WH2_k127_187395_4	411154.GFO_3498	6.473e-19	88.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1HXYP@117743|Flavobacteriia	976|Bacteroidetes	EF	ribose-phosphate pyrophosphokinase	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
WH2_k127_1887518_0	1123248.KB893348_gene195	5.511e-54	197.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,1ISF2@117747|Sphingobacteriia	976|Bacteroidetes	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
WH2_k127_1887518_2	1123257.AUFV01000007_gene351	7.831e-16	90.0	COG4447@1|root,COG4447@2|Bacteria,1RCNG@1224|Proteobacteria,1S4IP@1236|Gammaproteobacteria,1X9CQ@135614|Xanthomonadales	135614|Xanthomonadales	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
WH2_k127_1887518_1	1122176.KB903561_gene3589	4.444e-17	89.0	COG2010@1|root,COG2010@2|Bacteria,4PEWN@976|Bacteroidetes,1IXW6@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
WH2_k127_1910413_0	1408433.JHXV01000010_gene537	1.186e-269	859.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1HX49@117743|Flavobacteriia,2PA7Q@246874|Cryomorphaceae	976|Bacteroidetes	GV	PFAM Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3
WH2_k127_1910413_2	929703.KE386491_gene2810	9.612e-90	313.0	COG1136@1|root,COG1136@2|Bacteria,4NFCG@976|Bacteroidetes,47KXC@768503|Cytophagia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	-	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
WH2_k127_1910413_1	929703.KE386491_gene2811	1.305e-157	507.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,47MB4@768503|Cytophagia	976|Bacteroidetes	M	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
WH2_k127_1923557_1	385682.AFSL01000064_gene1724	8.368e-10	65.0	COG0810@1|root,COG0810@2|Bacteria,4NG4I@976|Bacteroidetes,2FM9A@200643|Bacteroidia,3XJ6S@558415|Marinilabiliaceae	976|Bacteroidetes	M	TonB family domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
WH2_k127_1923557_0	714943.Mucpa_1462	1.182e-127	420.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1IQU2@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
WH2_k127_1935820_1	755732.Fluta_2899	8.455e-33	133.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2PBEH@246874|Cryomorphaceae	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
WH2_k127_1935820_0	755732.Fluta_1778	1.404e-66	237.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4PI0B@976|Bacteroidetes,1IG7A@117743|Flavobacteriia,2PBJ3@246874|Cryomorphaceae	976|Bacteroidetes	O	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
WH2_k127_1942912_3	526222.Desal_3616	1.418e-05	50.0	COG0110@1|root,COG0110@2|Bacteria,1MZ7U@1224|Proteobacteria,42RVS@68525|delta/epsilon subdivisions,2WQYB@28221|Deltaproteobacteria,2M93C@213115|Desulfovibrionales	28221|Deltaproteobacteria	GM	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
WH2_k127_1942912_2	66377.JOBH01000001_gene1686	2.65e-06	59.0	COG5305@1|root,COG5305@2|Bacteria,2GN7C@201174|Actinobacteria	201174|Actinobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
WH2_k127_1942912_1	543632.JOJL01000047_gene3367	1.818e-10	70.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WH2_k127_1942912_0	862908.BMS_1252	3.255e-36	142.0	COG0454@1|root,COG0456@2|Bacteria,1N9KA@1224|Proteobacteria,431PF@68525|delta/epsilon subdivisions,2MTBE@213481|Bdellovibrionales,2WW76@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
WH2_k127_1946001_0	755732.Fluta_3528	2.604e-194	626.0	COG1233@1|root,COG1233@2|Bacteria,4P24Z@976|Bacteroidetes,1IITR@117743|Flavobacteriia	976|Bacteroidetes	C	COGs COG1233 Phytoene dehydrogenase and related protein	-	-	5.2.1.13	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R07512	RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_8
WH2_k127_1946001_1	1120965.AUBV01000005_gene1578	8.989e-27	116.0	COG4067@1|root,COG4067@2|Bacteria,4NS86@976|Bacteroidetes,47RH0@768503|Cytophagia	976|Bacteroidetes	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
WH2_k127_1950234_1	1408473.JHXO01000001_gene2073	1.1e-108	356.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,2FMX9@200643|Bacteroidia	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
WH2_k127_1950234_3	470145.BACCOP_00829	4.817e-11	74.0	COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,2FUKM@200643|Bacteroidia,4AQZF@815|Bacteroidaceae	976|Bacteroidetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
WH2_k127_1950234_2	509635.N824_03010	8.269e-31	122.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,1ITUQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
WH2_k127_1950234_0	1408473.JHXO01000001_gene2068	1.576e-163	535.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,2FM0W@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
WH2_k127_1965877_0	1124780.ANNU01000005_gene2467	4.403e-158	513.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
WH2_k127_1965877_1	616991.JPOO01000001_gene3753	8.823e-22	96.0	COG0644@1|root,COG0644@2|Bacteria,4NEI6@976|Bacteroidetes,1HYZB@117743|Flavobacteriia	976|Bacteroidetes	C	pyridine nucleotide-disulfide oxidoreductase	fixC	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
WH2_k127_1972227_1	1249997.JHZW01000002_gene1086	3.262e-92	312.0	COG0270@1|root,COG0270@2|Bacteria,4NG9A@976|Bacteroidetes,1HZAK@117743|Flavobacteriia,2PGUF@252356|Maribacter	976|Bacteroidetes	L	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
WH2_k127_1972227_2	1158318.ATXC01000001_gene948	0.0005638	48.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_2,TonB_C
WH2_k127_1972227_0	1453500.AT05_06150	1.543e-93	312.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WH2_k127_1974227_0	269798.CHU_0094	2.305e-306	947.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,47K9H@768503|Cytophagia	976|Bacteroidetes	L	DNA-directed DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
WH2_k127_1987715_0	946077.W5A_07717	1.911e-215	680.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1HX1Z@117743|Flavobacteriia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WH2_k127_1987715_1	1288963.ADIS_4297	2.301e-13	72.0	COG3714@1|root,COG3714@2|Bacteria,4NMZ9@976|Bacteroidetes,47RZ2@768503|Cytophagia	976|Bacteroidetes	S	PFAM YhhN-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
WH2_k127_2011737_2	1215092.PA6_021_01060	5.27e-42	160.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,1RPU9@1236|Gammaproteobacteria,1YDVI@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
WH2_k127_2011737_1	313596.RB2501_03445	7.921e-73	250.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,1HYG2@117743|Flavobacteriia	976|Bacteroidetes	S	isoleucine patch superfamily	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
WH2_k127_2011737_3	649349.Lbys_0867	5.641e-17	86.0	COG2608@1|root,COG2608@2|Bacteria,4NUTQ@976|Bacteroidetes,47S0M@768503|Cytophagia	976|Bacteroidetes	P	PFAM Heavy metal transport detoxification protein	-	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA
WH2_k127_2011737_0	1122605.KB893631_gene3942	2.713e-146	490.0	COG1629@1|root,COG2608@1|root,COG2608@2|Bacteria,COG4771@2|Bacteria,4NE7A@976|Bacteroidetes,1IP85@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,HMA,Plug,TonB_dep_Rec
WH2_k127_2020348_0	1453500.AT05_00420	1.525e-135	449.0	2CIBF@1|root,2Z85N@2|Bacteria,4NF0J@976|Bacteroidetes,1HYX2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2020348_1	1453500.AT05_05495	1.711e-18	100.0	2DMY7@1|root,32UCK@2|Bacteria,4NSK3@976|Bacteroidetes	976|Bacteroidetes	S	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Omp28
WH2_k127_2047258_0	886379.AEWI01000010_gene614	9.852e-56	204.0	COG5316@1|root,COG5316@2|Bacteria,4NGER@976|Bacteroidetes,2G3FN@200643|Bacteroidia,3XJXY@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
WH2_k127_2047258_3	926562.Oweho_0188	4.209e-10	69.0	COG2220@1|root,COG2220@2|Bacteria,4P2PR@976|Bacteroidetes,1I8QJ@117743|Flavobacteriia,2PAVG@246874|Cryomorphaceae	976|Bacteroidetes	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2047258_1	761193.Runsl_4449	2.782e-42	161.0	COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes,47QN1@768503|Cytophagia	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
WH2_k127_2047258_2	313606.M23134_05102	4.452e-27	113.0	COG2085@1|root,COG2085@2|Bacteria,4NEC7@976|Bacteroidetes,47QJ7@768503|Cytophagia	976|Bacteroidetes	S	Rossmann-like domain	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
WH2_k127_2069637_0	1408433.JHXV01000011_gene2096	1.142e-65	248.0	COG2706@1|root,COG3291@1|root,COG3292@1|root,COG4733@1|root,COG2706@2|Bacteria,COG3291@2|Bacteria,COG3292@2|Bacteria,COG4733@2|Bacteria,4PMMT@976|Bacteroidetes,1IJV8@117743|Flavobacteriia,2PBPE@246874|Cryomorphaceae	976|Bacteroidetes	GT	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
WH2_k127_2069637_1	1131814.JAFO01000001_gene4623	3.854e-38	143.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,3EYVH@335928|Xanthobacteraceae	28211|Alphaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
WH2_k127_2071056_0	755732.Fluta_2021	1.677e-79	287.0	COG3291@1|root,COG3291@2|Bacteria,4PFQY@976|Bacteroidetes,1ICPB@117743|Flavobacteriia,2PBH6@246874|Cryomorphaceae	976|Bacteroidetes	S	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta
WH2_k127_2071056_1	927658.AJUM01000037_gene2175	5.717e-28	119.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,2FN6Z@200643|Bacteroidia,3XJEX@558415|Marinilabiliaceae	976|Bacteroidetes	L	helicase superfamily c-terminal domain	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
WH2_k127_207732_1	1237149.C900_00337	1.13e-52	193.0	28MJC@1|root,2ZAVX@2|Bacteria,4NP81@976|Bacteroidetes,47Q3J@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_207732_0	1392498.JQLH01000001_gene571	1.261e-75	273.0	COG1216@1|root,COG1216@2|Bacteria,4NK0K@976|Bacteroidetes,1I0UB@117743|Flavobacteriia,2PHZ2@252356|Maribacter	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2082718_3	755732.Fluta_1481	1.378e-11	67.0	COG0604@1|root,COG0604@2|Bacteria,4NEYW@976|Bacteroidetes,1HYX1@117743|Flavobacteriia,2PBCQ@246874|Cryomorphaceae	976|Bacteroidetes	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,MaoC_dehydratas
WH2_k127_2082718_0	1094466.KQS_12610	6.796e-177	567.0	COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,1HY3T@117743|Flavobacteriia,2NT19@237|Flavobacterium	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
WH2_k127_2082718_2	1121459.AQXE01000005_gene1524	5.277e-54	194.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria,2MBFN@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
WH2_k127_2082718_1	1408433.JHXV01000001_gene715	1.914e-76	266.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1HXYD@117743|Flavobacteriia,2PB24@246874|Cryomorphaceae	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WH2_k127_2088814_2	1313301.AUGC01000006_gene181	5.741e-17	95.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
WH2_k127_2088814_0	1168034.FH5T_06740	6.944e-114	379.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,2FPWJ@200643|Bacteroidia	976|Bacteroidetes	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH2_k127_2088814_1	926562.Oweho_1848	3.402e-51	192.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,1HWSB@117743|Flavobacteriia,2PASI@246874|Cryomorphaceae	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
WH2_k127_2093648_0	1121889.AUDM01000004_gene2494	4.022e-123	406.0	COG3004@1|root,COG3004@2|Bacteria,4NFC4@976|Bacteroidetes,1HXXZ@117743|Flavobacteriia,2NS9U@237|Flavobacterium	976|Bacteroidetes	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
WH2_k127_2093648_1	1237149.C900_04326	8.352e-49	180.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia	976|Bacteroidetes	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
WH2_k127_2095320_0	1408433.JHXV01000015_gene1787	9.82e-112	369.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,1HWZA@117743|Flavobacteriia,2PA79@246874|Cryomorphaceae	976|Bacteroidetes	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
WH2_k127_2095320_1	926562.Oweho_2902	2.045e-24	110.0	COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,1I1XK@117743|Flavobacteriia,2PB63@246874|Cryomorphaceae	976|Bacteroidetes	L	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
WH2_k127_2099861_2	743722.Sph21_4357	1.287e-26	124.0	2CWCM@1|root,32SZF@2|Bacteria,4NSAZ@976|Bacteroidetes,1IT8H@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4260)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4260
WH2_k127_2099861_0	1121923.GPUN_2416	1.11e-91	309.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,464CC@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Exodeoxyribonuclease III	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
WH2_k127_2099861_1	269798.CHU_2920	2.686e-37	160.0	COG1361@1|root,COG4886@1|root,COG1361@2|Bacteria,COG4886@2|Bacteria,4NIM6@976|Bacteroidetes	976|Bacteroidetes	DZ	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
WH2_k127_2104276_0	1313421.JHBV01000003_gene659	3.138e-272	857.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IRKC@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
WH2_k127_214281_0	926562.Oweho_1808	2.629e-153	497.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,1HXAE@117743|Flavobacteriia,2PA4J@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid	kmo	-	1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
WH2_k127_214281_1	755732.Fluta_1605	2.07e-39	149.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1HWY8@117743|Flavobacteriia,2PAF8@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
WH2_k127_214281_2	78579.XP_003662530.1	5.643e-08	58.0	COG3844@1|root,KOG3846@2759|Eukaryota,38BHE@33154|Opisthokonta,3NUB7@4751|Fungi,3QJD4@4890|Ascomycota,216GT@147550|Sordariomycetes,3U6DJ@5139|Sordariales,3HEM6@35718|Chaetomiaceae	4751|Fungi	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	BNA5	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0030429,GO:0032787,GO:0034354,GO:0034627,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0051188,GO:0055086,GO:0070189,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
WH2_k127_2169525_1	391598.FBBAL38_06505	3.208e-94	314.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,1HXAU@117743|Flavobacteriia	976|Bacteroidetes	S	zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
WH2_k127_2169525_0	1239962.C943_01661	8.898e-208	657.0	COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,47M2I@768503|Cytophagia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
WH2_k127_2190662_0	1356852.N008_13565	2.459e-10	62.0	COG2057@1|root,COG2057@2|Bacteria,4NG9J@976|Bacteroidetes,47K21@768503|Cytophagia	976|Bacteroidetes	I	TIGRFAM 3-oxoacid CoA-transferase, B subunit	scoB	-	2.8.3.5,2.8.3.6	ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WH2_k127_2191062_3	760192.Halhy_1685	8.695e-58	206.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1ISH7@117747|Sphingobacteriia	976|Bacteroidetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH2_k127_2191062_4	313603.FB2170_04360	3.131e-37	147.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I2UG@117743|Flavobacteriia,2PHET@252356|Maribacter	976|Bacteroidetes	L	Single-strand binding protein family	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WH2_k127_2191062_5	926562.Oweho_0234	4.851e-35	137.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I2UG@117743|Flavobacteriia,2PB27@246874|Cryomorphaceae	976|Bacteroidetes	L	TIGRFAM single stranded DNA-binding protein (ssb)	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WH2_k127_2191062_8	709991.Odosp_2293	5.224e-06	55.0	COG0457@1|root,COG0457@2|Bacteria,4P45T@976|Bacteroidetes,2FYEG@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2191062_0	1122176.KB903544_gene726	8.902e-130	421.0	COG0524@1|root,COG0524@2|Bacteria,4NFJ9@976|Bacteroidetes,1INMS@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM pfkB family carbohydrate kinase	ydjH	-	-	-	-	-	-	-	-	-	-	-	PfkB
WH2_k127_2191062_1	1121481.AUAS01000001_gene4621	4.047e-77	266.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,47JBF@768503|Cytophagia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
WH2_k127_2191062_6	926562.Oweho_2398	1.467e-29	124.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,1I30B@117743|Flavobacteriia,2PB9N@246874|Cryomorphaceae	976|Bacteroidetes	I	Biotin-requiring enzyme	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
WH2_k127_2191062_2	1406840.Q763_08820	2.417e-62	220.0	COG0328@1|root,COG0328@2|Bacteria,4NNQX@976|Bacteroidetes,1I1AV@117743|Flavobacteriia,2NSXK@237|Flavobacterium	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
WH2_k127_2191062_7	667015.Bacsa_0099	5.295e-12	67.0	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,2FNCS@200643|Bacteroidia,4AMNR@815|Bacteroidaceae	976|Bacteroidetes	U	UPF0056 membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
WH2_k127_2196997_2	391596.PBAL39_13377	9.765e-11	74.0	COG3209@1|root,COG4447@1|root,COG3209@2|Bacteria,COG4447@2|Bacteria,4NE5D@976|Bacteroidetes,1IP6I@117747|Sphingobacteriia	976|Bacteroidetes	M	YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,TSP_3
WH2_k127_2196997_0	926562.Oweho_2144	3.107e-53	202.0	COG1225@1|root,COG1225@2|Bacteria,4NMEK@976|Bacteroidetes,1HYRW@117743|Flavobacteriia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WH2_k127_2196997_1	1235815.BAIX01000035_gene2010	3.513e-32	130.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,2FN59@200643|Bacteroidia	976|Bacteroidetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
WH2_k127_2198292_3	1370120.AUWR01000027_gene2504	2.338e-32	138.0	COG0614@1|root,COG0614@2|Bacteria,2IAFC@201174|Actinobacteria,23BFM@1762|Mycobacteriaceae	201174|Actinobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
WH2_k127_2198292_1	1177179.A11A3_02607	7.38e-46	175.0	COG4539@1|root,COG4539@2|Bacteria,1N1G8@1224|Proteobacteria,1S9FD@1236|Gammaproteobacteria,1XKKP@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
WH2_k127_2198292_2	1121920.AUAU01000004_gene618	2.691e-41	160.0	COG2318@1|root,COG2318@2|Bacteria,3Y53M@57723|Acidobacteria	57723|Acidobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WH2_k127_2198292_0	755732.Fluta_2588	1.656e-65	243.0	COG2374@1|root,COG2374@2|Bacteria,4NJUY@976|Bacteroidetes,1HXYB@117743|Flavobacteriia,2PBQS@246874|Cryomorphaceae	976|Bacteroidetes	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2198292_4	335543.Sfum_0955	8.567e-08	58.0	COG1434@1|root,COG1434@2|Bacteria,1NVJ0@1224|Proteobacteria	1224|Proteobacteria	S	Gram-negative-bacterium-type cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
WH2_k127_221102_0	643867.Ftrac_0939	1.817e-124	408.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,47M72@768503|Cytophagia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WH2_k127_221102_1	984262.SGRA_3632	5.093e-65	229.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,1IPAP@117747|Sphingobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
WH2_k127_2223089_0	984262.SGRA_1027	6.297e-102	343.0	COG1864@1|root,COG4085@1|root,COG1864@2|Bacteria,COG4085@2|Bacteria,4NFYJ@976|Bacteroidetes,1IY0Z@117747|Sphingobacteriia	976|Bacteroidetes	F	DNA/RNA non-specific endonuclease	nucA_1	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
WH2_k127_2223089_1	1506583.JQJY01000010_gene1173	2.791e-60	218.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia,2NUUX@237|Flavobacterium	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
WH2_k127_2223899_0	1137281.D778_00749	3.43e-237	746.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1HXCU@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
WH2_k127_2242270_0	1408433.JHXV01000006_gene2788	1.894e-127	437.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1HYBR@117743|Flavobacteriia,2PAP0@246874|Cryomorphaceae	976|Bacteroidetes	E	peptidase M1	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
WH2_k127_2242270_1	926562.Oweho_2422	3.902e-98	330.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1HWZZ@117743|Flavobacteriia,2PADT@246874|Cryomorphaceae	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
WH2_k127_2288521_0	860228.Ccan_02180	4.96e-182	574.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1HXDC@117743|Flavobacteriia,1EQ6S@1016|Capnocytophaga	976|Bacteroidetes	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
WH2_k127_2288521_4	1550091.JROE01000005_gene2007	2.718e-54	196.0	COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,1ISET@117747|Sphingobacteriia	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
WH2_k127_2288521_1	929556.Solca_3251	5.16e-156	511.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1IPRR@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WH2_k127_2288521_2	929556.Solca_3252	6.755e-111	367.0	COG0416@1|root,COG0416@2|Bacteria,4NHEX@976|Bacteroidetes,1IPMW@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
WH2_k127_2288521_6	867902.Ornrh_1369	1.949e-13	71.0	COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,1I53M@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
WH2_k127_2288521_5	28115.HR11_09680	1.638e-19	98.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,2FPCJ@200643|Bacteroidia,22XVX@171551|Porphyromonadaceae	976|Bacteroidetes	S	Uncharacterized ACR, COG1399	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
WH2_k127_2288521_3	1408433.JHXV01000007_gene2833	2.604e-66	230.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1HXBS@117743|Flavobacteriia,2PA8A@246874|Cryomorphaceae	976|Bacteroidetes	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WH2_k127_2301030_0	269798.CHU_2809	4.271e-154	495.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47K19@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
WH2_k127_2301030_1	1408433.JHXV01000002_gene334	4.955e-20	104.0	COG2374@1|root,COG4935@1|root,COG2374@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,LTD,SLH
WH2_k127_2301854_0	886379.AEWI01000146_gene3235	6.043e-97	342.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,2FM1J@200643|Bacteroidia,3XJIH@558415|Marinilabiliaceae	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
WH2_k127_2327985_0	1341155.FSS13T_00630	5.768e-123	404.0	COG2010@1|root,COG2010@2|Bacteria,4PMQB@976|Bacteroidetes,1IJZB@117743|Flavobacteriia,2NU2Y@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2327985_1	216432.CA2559_00200	1.834e-94	320.0	COG3291@1|root,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes,1IJEU@117743|Flavobacteriia	976|Bacteroidetes	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,MAM,UnbV_ASPIC,VCBS,fn3
WH2_k127_2352714_1	1356852.N008_11000	3.099e-48	177.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia	976|Bacteroidetes	DM	TIGRFAM capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
WH2_k127_2352714_2	1227739.Hsw_3674	6.599e-38	146.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia	976|Bacteroidetes	DM	TIGRFAM capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
WH2_k127_2352714_0	926549.KI421517_gene591	1.439e-50	191.0	COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,47PQR@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
WH2_k127_2365910_1	1122225.AULQ01000001_gene1525	2.03e-11	72.0	COG3391@1|root,COG3391@2|Bacteria,4PKUJ@976|Bacteroidetes,1IJFM@117743|Flavobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
WH2_k127_2365910_0	1356852.N008_13335	4.056e-49	184.0	COG0809@1|root,COG0809@2|Bacteria,4NDZ5@976|Bacteroidetes,47KMT@768503|Cytophagia	976|Bacteroidetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
WH2_k127_2372994_0	1408473.JHXO01000006_gene1161	2.288e-64	231.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,2FMTF@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
WH2_k127_2372994_2	1484460.JSWG01000009_gene275	4.35e-34	144.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	-
WH2_k127_2372994_3	1121861.KB899947_gene2415	6.293e-34	136.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2U9JM@28211|Alphaproteobacteria,2JSX8@204441|Rhodospirillales	204441|Rhodospirillales	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
WH2_k127_2372994_1	1121904.ARBP01000006_gene3731	2.295e-46	170.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,47MPC@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0659 Sulfate permease and related transporter (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
WH2_k127_2386552_0	204669.Acid345_2670	2.36e-92	331.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHB_HEX_C_1,PIG-L,VCBS,WxL
WH2_k127_2386552_1	945713.IALB_0051	1.89e-32	146.0	2C945@1|root,32W5M@2|Bacteria	2|Bacteria	-	-	-	-	5.4.4.1	ko:K01865	ko00627,ko01120,map00627,map01120	-	-	-	ko00000,ko00001,ko01000	-	-	-	-
WH2_k127_2389480_0	929556.Solca_3034	0.0	1081.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1INUJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WH2_k127_2389480_1	927658.AJUM01000040_gene839	4.331e-14	72.0	COG0051@1|root,COG0051@2|Bacteria,4NQ65@976|Bacteroidetes,2FT32@200643|Bacteroidia,3XK7T@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal protein S10p/S20e	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
WH2_k127_2392639_1	1250232.JQNJ01000001_gene1080	8.48e-75	258.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1HXMS@117743|Flavobacteriia	976|Bacteroidetes	C	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
WH2_k127_2392639_0	926562.Oweho_2547	4.77e-129	429.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1HXXH@117743|Flavobacteriia,2PBDE@246874|Cryomorphaceae	976|Bacteroidetes	O	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
WH2_k127_2393679_0	471854.Dfer_1247	2.674e-90	307.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,47JNP@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
WH2_k127_2393679_2	1453500.AT05_00970	1.178e-17	98.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
WH2_k127_2393679_1	1121957.ATVL01000014_gene1459	5.493e-39	163.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2450511_3	111780.Sta7437_0989	6.623e-34	135.0	COG0438@1|root,COG0438@2|Bacteria,1G1SZ@1117|Cyanobacteria,3VM1I@52604|Pleurocapsales	1117|Cyanobacteria	M	SPTR Glycosyl transferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
WH2_k127_2450511_0	1313421.JHBV01000042_gene3290	2.17e-157	513.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,1IVHN@117747|Sphingobacteriia	976|Bacteroidetes	P	COG1055 Na H antiporter NhaD and related arsenite	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
WH2_k127_2450511_4	760192.Halhy_1935	2.46e-19	94.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1IZFK@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
WH2_k127_2450511_2	643867.Ftrac_2338	3.292e-42	175.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,47M33@768503|Cytophagia	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, crp family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WH2_k127_2450511_1	760192.Halhy_6224	2.555e-105	351.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,1IP0G@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WH2_k127_2450511_5	938709.AUSH02000051_gene233	5.229e-10	69.0	COG3210@1|root,COG3210@2|Bacteria,4PPCP@976|Bacteroidetes	976|Bacteroidetes	U	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
WH2_k127_2458874_2	983544.Lacal_0194	3.398e-14	79.0	COG2225@1|root,COG2225@2|Bacteria,4NF5H@976|Bacteroidetes,1HXIY@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the malate synthase family	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
WH2_k127_2458874_1	761193.Runsl_2947	2.463e-57	207.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,47K8M@768503|Cytophagia	976|Bacteroidetes	O	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
WH2_k127_2458874_0	926549.KI421517_gene2586	8.287e-61	220.0	COG1073@1|root,COG1073@2|Bacteria,4NGCE@976|Bacteroidetes,47PN6@768503|Cytophagia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
WH2_k127_2469937_0	760192.Halhy_3824	4.8e-197	635.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
WH2_k127_2469937_2	485918.Cpin_0478	1.595e-13	83.0	COG2318@1|root,COG2318@2|Bacteria,4NP2C@976|Bacteroidetes,1ITXI@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WH2_k127_2469937_1	313606.M23134_01922	1.594e-47	178.0	COG0664@1|root,COG0664@2|Bacteria,4NN09@976|Bacteroidetes,47XMK@768503|Cytophagia	976|Bacteroidetes	T	Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
WH2_k127_247246_1	1279009.ADICEAN_01375	1.836e-30	122.0	2CEJ5@1|root,2Z7RK@2|Bacteria,4NGWQ@976|Bacteroidetes,47N0C@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
WH2_k127_247246_0	1123234.AUKI01000011_gene1016	3.937e-110	365.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes,1HWQR@117743|Flavobacteriia	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	wbpP	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
WH2_k127_2484663_1	929556.Solca_2741	5.132e-68	232.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1IQU9@117747|Sphingobacteriia	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
WH2_k127_2484663_0	509635.N824_17285	6.927e-162	523.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1INPJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WH2_k127_2484663_2	1122176.KB903576_gene4958	1.357e-07	57.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1INPJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WH2_k127_2487287_6	1121904.ARBP01000002_gene7150	1.521e-21	97.0	COG3291@1|root,COG3291@2|Bacteria,4NJ9V@976|Bacteroidetes,47N8F@768503|Cytophagia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
WH2_k127_2487287_3	316067.Geob_3308	2.301e-50	208.0	COG2373@1|root,COG3291@1|root,COG5276@1|root,COG2373@2|Bacteria,COG3291@2|Bacteria,COG5276@2|Bacteria,1R7A1@1224|Proteobacteria,42Y4U@68525|delta/epsilon subdivisions,2WU72@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,IgGFc_binding
WH2_k127_2487287_4	582515.KR51_00000010	2.548e-24	122.0	COG1572@1|root,COG2304@1|root,COG2931@1|root,COG3210@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1G39H@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Calx-beta,HemolysinCabind,RHS_repeat
WH2_k127_2487287_2	153721.MYP_3989	2.974e-61	244.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,47MGN@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
WH2_k127_2487287_1	84531.JMTZ01000011_gene3075	4.098e-86	292.0	COG0388@1|root,COG0388@2|Bacteria,1MXBR@1224|Proteobacteria,1RQ4Z@1236|Gammaproteobacteria,1X4JY@135614|Xanthomonadales	135614|Xanthomonadales	S	carbon-nitrogen hydrolase	-	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
WH2_k127_2487287_0	1211114.ALIP01000042_gene487	4.365e-151	486.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1X49S@135614|Xanthomonadales	135614|Xanthomonadales	E	aminotransferase	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
WH2_k127_2487287_5	1120965.AUBV01000008_gene2109	6.318e-22	100.0	COG2361@1|root,COG2361@2|Bacteria,4NV8D@976|Bacteroidetes,47W04@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
WH2_k127_2487287_7	765914.ThisiDRAFT_0906	4.949e-07	53.0	COG1669@1|root,COG1669@2|Bacteria,1N9G2@1224|Proteobacteria,1SZEB@1236|Gammaproteobacteria,1X2JZ@135613|Chromatiales	135613|Chromatiales	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
WH2_k127_2494549_1	1250232.JQNJ01000001_gene1252	4.05e-30	123.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,1HXGK@117743|Flavobacteriia	976|Bacteroidetes	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
WH2_k127_2494549_0	1123248.KB893326_gene1472	2.963e-138	445.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1INP0@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WH2_k127_2496335_2	700598.Niako_2258	1.545e-64	227.0	COG1814@1|root,COG1814@2|Bacteria,4NE6W@976|Bacteroidetes,1IRNA@117747|Sphingobacteriia	976|Bacteroidetes	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
WH2_k127_2496335_1	1120966.AUBU01000014_gene583	7.063e-74	258.0	COG3217@1|root,COG3217@2|Bacteria,4NG33@976|Bacteroidetes,47PMH@768503|Cytophagia	976|Bacteroidetes	S	beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
WH2_k127_2496335_0	1122176.KB903546_gene1028	2.115e-152	509.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	manA5	-	3.2.1.51,3.2.1.78	ko:K01206,ko:K01218	ko00051,ko00511,ko02024,map00051,map00511,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko04147	-	GH26,GH29	-	Alpha_L_fucos,Cytochrome_C554,Glyco_hydro_26,PA14,RsgI_N
WH2_k127_2496335_3	1408433.JHXV01000028_gene2125	1.079e-13	76.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia,2PBC5@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TPR_16,TPR_8
WH2_k127_2497194_3	1230341.MJ3_09608	3.162e-13	79.0	COG2244@1|root,COG2244@2|Bacteria,1UXZ7@1239|Firmicutes,4HGGI@91061|Bacilli	91061|Bacilli	S	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
WH2_k127_2497194_1	313596.RB2501_00121	4.722e-64	225.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,1I1CS@117743|Flavobacteriia	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
WH2_k127_2497194_0	1349822.NSB1T_01555	1.07e-67	243.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,2FNMC@200643|Bacteroidia,22WV1@171551|Porphyromonadaceae	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
WH2_k127_2497194_2	1033732.CAHI01000030_gene1191	6.007e-26	119.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,2FPS4@200643|Bacteroidia,22UHM@171550|Rikenellaceae	976|Bacteroidetes	S	PASTA domain	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
WH2_k127_2515074_0	1121373.KB903621_gene1813	1.708e-42	170.0	COG3531@1|root,COG3531@2|Bacteria,4NQKI@976|Bacteroidetes,47QFT@768503|Cytophagia	976|Bacteroidetes	O	DSBA-like thioredoxin domain	dsbC	-	-	ko:K07396	-	-	-	-	ko00000	-	-	-	DSBA,Thioredoxin_5
WH2_k127_2515074_1	1500257.JQNM01000013_gene2829	3.417e-42	158.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,2U960@28211|Alphaproteobacteria,4BFSX@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
WH2_k127_2522040_2	1121887.AUDK01000010_gene1416	2.209e-37	149.0	COG0346@1|root,COG0346@2|Bacteria,4NQRN@976|Bacteroidetes,1I2S1@117743|Flavobacteriia,2NWXQ@237|Flavobacterium	976|Bacteroidetes	E	bleomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
WH2_k127_2522040_0	1034347.CAHJ01000066_gene2946	2.826e-66	241.0	COG4430@1|root,COG4430@2|Bacteria,1UYP9@1239|Firmicutes,4HDZD@91061|Bacilli,1ZDB7@1386|Bacillus	91061|Bacilli	S	Bacteriocin-protection, YdeI or OmpD-Associated	ydeI	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
WH2_k127_2522040_1	388051.AUFE01000021_gene89	6.836e-54	204.0	COG5649@1|root,COG5649@2|Bacteria,1RDDG@1224|Proteobacteria,2W0C7@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WH2_k127_2539532_2	755732.Fluta_1203	2.345e-16	83.0	COG2385@1|root,COG2385@2|Bacteria,4NG21@976|Bacteroidetes,1I7GW@117743|Flavobacteriia,2PAW4@246874|Cryomorphaceae	976|Bacteroidetes	D	Stage II sporulation protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	DUF4922,Glycos_transf_2,SpoIID
WH2_k127_2539532_3	391596.PBAL39_09891	2.201e-05	57.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1IPFX@117747|Sphingobacteriia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
WH2_k127_2539532_1	269798.CHU_1051	3.382e-22	111.0	COG5276@1|root,COG5276@2|Bacteria,4PKN2@976|Bacteroidetes,47S6E@768503|Cytophagia	976|Bacteroidetes	G	NPCBM/NEW2 domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CBM_6,LVIVD,NPCBM
WH2_k127_2556258_3	1304877.KI519400_gene1660	1.365e-05	53.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TQKF@28211|Alphaproteobacteria,3JT38@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
WH2_k127_2556258_1	485918.Cpin_1189	1.339e-65	229.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1IPP6@117747|Sphingobacteriia	976|Bacteroidetes	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
WH2_k127_2556258_2	755732.Fluta_2422	3.631e-19	98.0	29BEQ@1|root,2ZYD2@2|Bacteria,4PD0R@976|Bacteroidetes,1ICRX@117743|Flavobacteriia,2PBXT@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2556258_0	1313421.JHBV01000043_gene3177	2.794e-102	345.0	COG1804@1|root,COG1804@2|Bacteria,4NEA8@976|Bacteroidetes,1IQ7F@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
WH2_k127_2559272_1	1313421.JHBV01000047_gene140	2.813e-101	334.0	COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,1IP3D@117747|Sphingobacteriia	976|Bacteroidetes	M	Sugar nucleotidyl transferase	glmU	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
WH2_k127_2559272_0	1380384.JADN01000007_gene1690	8.55e-201	638.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WH2_k127_259252_0	869213.JCM21142_93644	3.735e-22	100.0	COG0438@1|root,COG0438@2|Bacteria,4NMHA@976|Bacteroidetes,47XDA@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
WH2_k127_2606711_1	936455.KI421499_gene6339	1.151e-21	94.0	COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,2TTR0@28211|Alphaproteobacteria,3JRTX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
WH2_k127_2606711_0	999419.HMPREF1077_02017	1.8e-93	318.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,2FM5V@200643|Bacteroidia,22VZV@171551|Porphyromonadaceae	976|Bacteroidetes	M	transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
WH2_k127_2609572_0	755732.Fluta_0943	1.487e-98	323.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,1HWYC@117743|Flavobacteriia,2PAB5@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
WH2_k127_2609572_1	1121859.KB890739_gene2271	8.167e-30	132.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,47Q9A@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH2_k127_2609572_2	883158.HMPREF9140_01693	4.329e-06	51.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,2FNS9@200643|Bacteroidia	976|Bacteroidetes	M	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
WH2_k127_2614120_0	755732.Fluta_3528	2.078e-191	613.0	COG1233@1|root,COG1233@2|Bacteria,4P24Z@976|Bacteroidetes,1IITR@117743|Flavobacteriia	976|Bacteroidetes	C	COGs COG1233 Phytoene dehydrogenase and related protein	-	-	5.2.1.13	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R07512	RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_8
WH2_k127_2614120_1	1348583.ATLH01000005_gene902	3.322e-16	85.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes,1HXSH@117743|Flavobacteriia,1F8CE@104264|Cellulophaga	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
WH2_k127_2620309_0	755732.Fluta_2550	1.862e-230	754.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1HYJD@117743|Flavobacteriia,2PAHV@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
WH2_k127_2640297_1	742766.HMPREF9455_01526	8.689e-37	147.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,2FME2@200643|Bacteroidia,22XZ6@171551|Porphyromonadaceae	976|Bacteroidetes	M	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
WH2_k127_2640297_0	1408433.JHXV01000032_gene1130	2.097e-150	481.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1HY6Y@117743|Flavobacteriia,2PA5T@246874|Cryomorphaceae	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
WH2_k127_2653051_1	452471.Aasi_0331	1.552e-08	59.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,47KSQ@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
WH2_k127_2653051_0	927658.AJUM01000047_gene2949	1.08e-222	696.0	COG0538@1|root,COG0538@2|Bacteria,4NDY2@976|Bacteroidetes,2FQZ2@200643|Bacteroidia,3XJJG@558415|Marinilabiliaceae	976|Bacteroidetes	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WH2_k127_2654897_4	984262.SGRA_0761	3.914e-16	79.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,1IPMS@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
WH2_k127_2654897_1	1150600.ADIARSV_1265	2.463e-93	318.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,1IPDJ@117747|Sphingobacteriia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
WH2_k127_2654897_3	742725.HMPREF9450_01149	2.798e-19	96.0	2E6VD@1|root,331EZ@2|Bacteria,4NUSW@976|Bacteroidetes,2FTVZ@200643|Bacteroidia,22UKM@171550|Rikenellaceae	976|Bacteroidetes	S	Protein of unknown function (DUF3098)	fjo13	-	-	-	-	-	-	-	-	-	-	-	DUF3098
WH2_k127_2654897_2	743722.Sph21_0547	9.556e-65	232.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,1INNN@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
WH2_k127_2654897_0	926562.Oweho_2745	3.382e-126	409.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1HY4A@117743|Flavobacteriia,2PAA7@246874|Cryomorphaceae	976|Bacteroidetes	J	PFAM tRNA synthetases class I (I, L, M and V)	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
WH2_k127_2661555_2	1121904.ARBP01000021_gene3540	1.515e-32	131.0	COG0492@1|root,COG0492@2|Bacteria,4NEC8@976|Bacteroidetes,47MC4@768503|Cytophagia	976|Bacteroidetes	O	Pyridine nucleotide-disulphide oxidoreductase	ahpF	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
WH2_k127_2661555_3	485918.Cpin_5627	6.185e-21	97.0	COG3224@1|root,COG3224@2|Bacteria,4P7R6@976|Bacteroidetes,1IZSY@117747|Sphingobacteriia	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2661555_1	1121007.AUML01000008_gene1038	1.882e-67	248.0	COG2207@1|root,COG2207@2|Bacteria,4NMQR@976|Bacteroidetes,1I1QC@117743|Flavobacteriia,2YITV@290174|Aquimarina	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
WH2_k127_2661555_4	468059.AUHA01000002_gene249	5.776e-13	74.0	2FAA5@1|root,342IS@2|Bacteria,4P4T1@976|Bacteroidetes	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
WH2_k127_2661555_0	760192.Halhy_5751	6.543e-143	462.0	2CK59@1|root,335GM@2|Bacteria,4NYUR@976|Bacteroidetes,1IWCN@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2669323_0	1223410.KN050846_gene1904	2.097e-129	424.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,1HWX0@117743|Flavobacteriia	976|Bacteroidetes	M	NAD-dependent epimerase	ltd	-	-	-	-	-	-	-	-	-	-	-	Epimerase
WH2_k127_2669323_1	869213.JCM21142_41872	5.068e-52	190.0	COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,47JH6@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0176 family	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
WH2_k127_2675646_1	1349767.GJA_3704	1.43e-19	89.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,476EK@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9
WH2_k127_2675646_0	204669.Acid345_1812	3.742e-54	210.0	COG0745@1|root,COG2202@1|root,COG4251@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG4251@2|Bacteria,3Y4QP@57723|Acidobacteria,2JP3I@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WH2_k127_2676026_1	1121899.Q764_10825	1.439e-10	63.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,1HWR8@117743|Flavobacteriia,2NSFJ@237|Flavobacterium	976|Bacteroidetes	E	Oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
WH2_k127_2676026_0	700598.Niako_0136	5.866e-89	321.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,1IQPG@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2373 Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
WH2_k127_268562_1	1121889.AUDM01000008_gene785	2.358e-23	106.0	2AMB7@1|root,31C6A@2|Bacteria,4NQ8I@976|Bacteroidetes,1I345@117743|Flavobacteriia,2NWUI@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_268562_0	694427.Palpr_0940	4.845e-82	284.0	COG1230@1|root,COG1230@2|Bacteria,4NIHB@976|Bacteroidetes,2FNQ7@200643|Bacteroidia,22W19@171551|Porphyromonadaceae	976|Bacteroidetes	P	Transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
WH2_k127_2696751_1	314256.OG2516_01796	1.421e-42	160.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2U59K@28211|Alphaproteobacteria,2PCW7@252301|Oceanicola	28211|Alphaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
WH2_k127_2696751_2	414684.RC1_2049	8.095e-13	76.0	COG4704@1|root,COG4704@2|Bacteria,1N6RE@1224|Proteobacteria,2UFAH@28211|Alphaproteobacteria,2JUF3@204441|Rhodospirillales	204441|Rhodospirillales	S	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
WH2_k127_2696751_0	1185876.BN8_01308	2.162e-48	181.0	COG1778@1|root,COG1778@2|Bacteria,4NMFZ@976|Bacteroidetes,47PAE@768503|Cytophagia	976|Bacteroidetes	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	-
WH2_k127_2706241_0	313596.RB2501_03025	2.417e-55	199.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1I1XN@117743|Flavobacteriia	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
WH2_k127_2706241_1	755732.Fluta_0748	2.919e-26	120.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
WH2_k127_2730395_2	103690.17132052	3.519e-22	97.0	COG2442@1|root,COG2442@2|Bacteria,1G7V4@1117|Cyanobacteria,1HP8S@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
WH2_k127_2730395_0	755732.Fluta_1356	6.028e-121	412.0	COG3975@1|root,COG3975@2|Bacteria,4NE4D@976|Bacteroidetes,1HXD0@117743|Flavobacteriia,2PAUW@246874|Cryomorphaceae	976|Bacteroidetes	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
WH2_k127_2730395_1	1121098.HMPREF1534_00173	4.997e-56	198.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,2FMM2@200643|Bacteroidia,4AM39@815|Bacteroidaceae	976|Bacteroidetes	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
WH2_k127_274389_1	929556.Solca_0519	1.515e-32	131.0	COG2010@1|root,COG2010@2|Bacteria,4NQE3@976|Bacteroidetes,1IU8D@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrome_CBB3
WH2_k127_274389_0	1484460.JSWG01000008_gene1892	1.601e-105	357.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HZIA@117743|Flavobacteriia	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
WH2_k127_2745910_0	1278073.MYSTI_00938	1.619e-64	229.0	COG0251@1|root,COG0251@2|Bacteria,1MYEM@1224|Proteobacteria,438KW@68525|delta/epsilon subdivisions,2X3V9@28221|Deltaproteobacteria,2YX7P@29|Myxococcales	28221|Deltaproteobacteria	J	Endoribonuclease L-PSP	-	-	3.5.99.5	ko:K15067	ko00380,map00380	-	R03887	RC01015	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
WH2_k127_2745910_1	1144275.COCOR_06850	3.727e-28	118.0	COG2311@1|root,COG2311@2|Bacteria,1RI24@1224|Proteobacteria,42ZYC@68525|delta/epsilon subdivisions,2X468@28221|Deltaproteobacteria,2YYC6@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
WH2_k127_2748134_0	1121875.KB907550_gene717	4.519e-114	393.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_12,TPR_8
WH2_k127_2748134_1	1122179.KB890425_gene3428	8.001e-06	58.0	COG1404@1|root,COG2356@1|root,COG3291@1|root,COG1404@2|Bacteria,COG2356@2|Bacteria,COG3291@2|Bacteria,4PPF8@976|Bacteroidetes	976|Bacteroidetes	O	Reprolysin (M12B) family zinc metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_5
WH2_k127_27528_2	1122176.KB903546_gene971	0.0002285	50.0	2EFNW@1|root,339EZ@2|Bacteria,4NV29@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_27528_0	755732.Fluta_0880	1.621e-101	340.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1HXNN@117743|Flavobacteriia,2PAAD@246874|Cryomorphaceae	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
WH2_k127_27528_1	1453500.AT05_11130	3.106e-24	103.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,1HXMK@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
WH2_k127_2753705_0	1121007.AUML01000055_gene2942	4.846e-153	519.0	COG2931@1|root,COG4733@1|root,COG2931@2|Bacteria,COG4733@2|Bacteria,4PP90@976|Bacteroidetes,1IKGM@117743|Flavobacteriia,2YHK4@290174|Aquimarina	976|Bacteroidetes	Q	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,MAM,Peptidase_M36
WH2_k127_2753705_3	391587.KAOT1_09064	8.294e-35	155.0	2DBH5@1|root,2Z97Q@2|Bacteria,4NK7F@976|Bacteroidetes,1I14F@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2753705_2	714943.Mucpa_1621	2.824e-53	189.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1ISZS@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WH2_k127_2753705_1	760192.Halhy_5231	1.108e-54	198.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1INY3@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS,Response_reg
WH2_k127_2801206_1	926549.KI421517_gene2262	1.453e-13	80.0	COG0382@1|root,COG0382@2|Bacteria,4P9RC@976|Bacteroidetes,47RXG@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
WH2_k127_2801206_0	755732.Fluta_1605	9.166e-133	431.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1HWY8@117743|Flavobacteriia,2PAF8@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
WH2_k127_2842593_2	1288963.ADIS_2231	9.85e-25	104.0	COG0798@1|root,COG0798@2|Bacteria,4NFG7@976|Bacteroidetes,47M0B@768503|Cytophagia	976|Bacteroidetes	P	PFAM Sodium Bile acid symporter family	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
WH2_k127_2842593_1	1239962.C943_03663	1.777e-51	190.0	COG2318@1|root,COG2318@2|Bacteria,4NNJ3@976|Bacteroidetes,47RJ8@768503|Cytophagia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB,DinB_2
WH2_k127_2842593_0	616991.JPOO01000001_gene3356	1.476e-174	560.0	COG0477@1|root,COG0607@1|root,COG0607@2|Bacteria,COG2814@2|Bacteria,4NEN9@976|Bacteroidetes,1HZ4T@117743|Flavobacteriia	976|Bacteroidetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH2_k127_2842627_0	1137281.D778_01484	2.149e-43	172.0	2DBH5@1|root,2Z97Q@2|Bacteria,4NK7F@976|Bacteroidetes,1I14F@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2842627_1	938709.AUSH02000020_gene1990	8.213e-13	78.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Fib_succ_major
WH2_k127_2842627_2	1174528.JH992898_gene4644	2.716e-12	76.0	COG1572@1|root,COG4675@1|root,COG1572@2|Bacteria,COG4675@2|Bacteria,1G8V2@1117|Cyanobacteria	1117|Cyanobacteria	S	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
WH2_k127_2844450_1	929703.KE386491_gene3466	1.383e-195	615.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,47JN6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WH2_k127_2844450_0	929556.Solca_1191	1.156e-225	720.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1IQ72@117747|Sphingobacteriia	976|Bacteroidetes	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
WH2_k127_2844450_2	1406840.Q763_10825	1.232e-36	147.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,1HYB1@117743|Flavobacteriia,2NTJ7@237|Flavobacterium	976|Bacteroidetes	O	Peptidase, M22	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
WH2_k127_2844450_3	880070.Cycma_4912	5.088e-21	97.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,47M95@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
WH2_k127_2852408_0	504472.Slin_4957	2.605e-93	316.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47KGA@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	amaA	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WH2_k127_2852408_2	1121896.JMLU01000003_gene2078	4.06e-34	134.0	COG0730@1|root,COG0730@2|Bacteria,4NTZ8@976|Bacteroidetes,1I2UM@117743|Flavobacteriia,2NWMD@237|Flavobacterium	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WH2_k127_2852408_1	926562.Oweho_1807	3.473e-48	176.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1I8E9@117743|Flavobacteriia,2PBCC@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM WD40-like beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
WH2_k127_2857170_1	755732.Fluta_2606	4.466e-31	126.0	28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,1I8RM@117743|Flavobacteriia	976|Bacteroidetes	S	S1 P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease,Zn_dep_PLPC
WH2_k127_2857170_2	1396141.BATP01000047_gene3931	1.609e-11	71.0	2EHW5@1|root,33BMQ@2|Bacteria,46WAC@74201|Verrucomicrobia,2IWH5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2857170_0	1122176.KB903587_gene4484	6.994e-114	384.0	COG2234@1|root,COG2234@2|Bacteria,4NENF@976|Bacteroidetes,1IPRF@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WH2_k127_2879195_1	96561.Dole_3112	1.971e-53	205.0	2DM58@1|root,31S4C@2|Bacteria,1RGAH@1224|Proteobacteria,431QP@68525|delta/epsilon subdivisions,2WWXE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2879195_2	1121957.ATVL01000009_gene1252	6.81e-43	179.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,47PRE@768503|Cytophagia	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
WH2_k127_2879195_0	760192.Halhy_0269	7.324e-96	317.0	COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,1IQFD@117747|Sphingobacteriia	976|Bacteroidetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
WH2_k127_2896151_3	1122179.KB890491_gene4529	7.976e-06	48.0	2EN2B@1|root,33FQI@2|Bacteria,4NY51@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2896151_1	1349785.BAUG01000054_gene2431	1.169e-39	155.0	28H8R@1|root,2Z7KJ@2|Bacteria,4NGZN@976|Bacteroidetes,1I08A@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2896151_0	485918.Cpin_6932	2.01e-76	262.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1IQ8P@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
WH2_k127_2896151_2	714943.Mucpa_0218	2.158e-14	83.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
WH2_k127_2909845_0	63737.Npun_R6588	2.639e-309	979.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HQV2@1161|Nostocales	1117|Cyanobacteria	Q	Pfam:HxxPF_rpt	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
WH2_k127_2909845_1	1297742.A176_00772	5.642e-12	70.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WN7A@28221|Deltaproteobacteria,2YTZA@29|Myxococcales	28221|Deltaproteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
WH2_k127_2911782_1	1122179.KB890469_gene619	3.245e-240	769.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
WH2_k127_2911782_0	1122179.KB890469_gene619	2.626e-261	837.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
WH2_k127_2916624_1	755732.Fluta_1182	4.102e-124	400.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia,2PABZ@246874|Cryomorphaceae	976|Bacteroidetes	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
WH2_k127_2916624_2	755732.Fluta_1181	5.776e-72	247.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1HXN6@117743|Flavobacteriia,2PAX8@246874|Cryomorphaceae	976|Bacteroidetes	C	Protein of unknown function (DUF3341)	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
WH2_k127_2916624_3	929556.Solca_3365	5.962e-45	171.0	COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,1IRVN@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome C	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
WH2_k127_2916624_0	755732.Fluta_1179	9.523e-129	429.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,1HY1X@117743|Flavobacteriia,2PAAV@246874|Cryomorphaceae	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2923050_0	269798.CHU_2552	4.063e-10	69.0	COG2885@1|root,COG5184@1|root,COG2885@2|Bacteria,COG5184@2|Bacteria,4PM26@976|Bacteroidetes,47Y04@768503|Cytophagia	976|Bacteroidetes	GM	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2923050_1	755732.Fluta_1673	1.938e-07	63.0	COG2911@1|root,COG3266@1|root,COG2911@2|Bacteria,COG3266@2|Bacteria,4PKFD@976|Bacteroidetes,1IKC5@117743|Flavobacteriia	976|Bacteroidetes	S	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
WH2_k127_2946426_1	1408433.JHXV01000005_gene2262	4.145e-19	97.0	2CA1R@1|root,32FVT@2|Bacteria,4PBTZ@976|Bacteroidetes,1I9V5@117743|Flavobacteriia,2PBA8@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
WH2_k127_2946426_0	1453500.AT05_03350	7.423e-114	369.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,1HWQ0@117743|Flavobacteriia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WH2_k127_2950857_1	742817.HMPREF9449_02620	1.448e-18	92.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,2FMV3@200643|Bacteroidia,22W54@171551|Porphyromonadaceae	976|Bacteroidetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
WH2_k127_2950857_3	755732.Fluta_1909	8.792e-14	76.0	2DNED@1|root,30W9S@2|Bacteria,4P9NX@976|Bacteroidetes,1IE9S@117743|Flavobacteriia,2PBY6@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2950857_0	755732.Fluta_1910	4.157e-172	556.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1HX84@117743|Flavobacteriia,2PAH6@246874|Cryomorphaceae	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
WH2_k127_2950857_2	755732.Fluta_1273	1.692e-16	85.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1HYN2@117743|Flavobacteriia,2PC2Y@246874|Cryomorphaceae	976|Bacteroidetes	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
WH2_k127_2953517_2	1089547.KB913013_gene4641	2.031e-18	94.0	COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,47NSZ@768503|Cytophagia	976|Bacteroidetes	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
WH2_k127_2953517_1	761193.Runsl_0112	4.592e-53	198.0	COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,47NSZ@768503|Cytophagia	976|Bacteroidetes	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
WH2_k127_2953517_0	761193.Runsl_0111	1.333e-235	734.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,47KTB@768503|Cytophagia	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
WH2_k127_2969782_1	755732.Fluta_1586	1.366e-21	104.0	COG4773@1|root,COG4773@2|Bacteria,4PKTX@976|Bacteroidetes,1HXIR@117743|Flavobacteriia,2PB19@246874|Cryomorphaceae	976|Bacteroidetes	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
WH2_k127_2969782_0	1168289.AJKI01000056_gene3050	2.092e-70	256.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,2FM3C@200643|Bacteroidia,3XJUZ@558415|Marinilabiliaceae	976|Bacteroidetes	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
WH2_k127_2976177_0	655815.ZPR_3056	2.417e-65	225.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HY0V@117743|Flavobacteriia	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
WH2_k127_2976177_1	379066.GAU_1241	2.956e-24	106.0	COG2267@1|root,COG2267@2|Bacteria,1ZUJI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Alpha/beta hydrolase family	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
WH2_k127_2977381_2	1237149.C900_00118	8.733e-12	70.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,47JC4@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
WH2_k127_2977381_1	1121285.AUFK01000017_gene3099	1.19e-86	303.0	COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,1HXZJ@117743|Flavobacteriia,3ZQ9C@59732|Chryseobacterium	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
WH2_k127_2977381_0	925409.KI911562_gene1745	4.698e-103	342.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1IPUI@117747|Sphingobacteriia	976|Bacteroidetes	P	Metal ABC transporter ATPase	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
WH2_k127_2979332_1	1122182.KB903814_gene3299	8.056e-09	69.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4D9K4@85008|Micromonosporales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_10,TPR_12,TPR_7,TPR_8,Trans_reg_C
WH2_k127_2979332_0	1123248.KB893325_gene1164	2.573e-84	289.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,1IPC6@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
WH2_k127_2979332_2	1244528.CFT03427_1518	2.076e-07	56.0	COG1846@1|root,COG1846@2|Bacteria,1RM3A@1224|Proteobacteria,42SQ5@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
WH2_k127_2991225_3	755732.Fluta_2914	8.885e-21	104.0	2A94Q@1|root,30Y8X@2|Bacteria,4PC05@976|Bacteroidetes,1ICS0@117743|Flavobacteriia,2PBYD@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2991225_2	1121373.KB903641_gene3706	4.84e-41	170.0	2C4MF@1|root,300D5@2|Bacteria,4NPEA@976|Bacteroidetes,47RYT@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_2991225_0	1250006.JHZZ01000001_gene226	7.808e-173	551.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1HXHG@117743|Flavobacteriia,3VV2G@52959|Polaribacter	976|Bacteroidetes	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
WH2_k127_2991225_1	1131812.JQMS01000001_gene2726	8.552e-48	183.0	COG1470@1|root,COG2304@1|root,COG3209@1|root,COG3391@1|root,COG1470@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia,2P0VG@237|Flavobacterium	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF5011,HYR,SprB
WH2_k127_2996925_1	504472.Slin_0183	0.0001428	50.0	COG0729@1|root,COG5295@1|root,COG0729@2|Bacteria,COG5295@2|Bacteria,4NVBC@976|Bacteroidetes,47Y1F@768503|Cytophagia	976|Bacteroidetes	M	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
WH2_k127_2996925_0	269798.CHU_2552	4.043e-17	92.0	COG2885@1|root,COG5184@1|root,COG2885@2|Bacteria,COG5184@2|Bacteria,4PM26@976|Bacteroidetes,47Y04@768503|Cytophagia	976|Bacteroidetes	GM	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3008792_0	307480.IW16_20090	2.764e-47	173.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1HWYW@117743|Flavobacteriia,3ZNTT@59732|Chryseobacterium	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WH2_k127_3008792_1	889378.Spiaf_0605	0.00011	53.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
WH2_k127_3043427_1	56780.SYN_00823	3.422e-50	191.0	COG0438@1|root,COG0438@2|Bacteria,1PDZU@1224|Proteobacteria,42WD7@68525|delta/epsilon subdivisions,2WV5B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
WH2_k127_3043427_0	1121459.AQXE01000004_gene1766	2.4e-50	185.0	COG0438@1|root,COG0438@2|Bacteria,1PGDM@1224|Proteobacteria,4363T@68525|delta/epsilon subdivisions,2X9FF@28221|Deltaproteobacteria,2MCV1@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH2_k127_3050411_2	247490.KSU1_C1631	8.31e-13	78.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,2IX8E@203682|Planctomycetes	203682|Planctomycetes	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
WH2_k127_3050411_1	1356852.N008_04025	2.685e-73	271.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,4PM5K@976|Bacteroidetes,47MDR@768503|Cytophagia	976|Bacteroidetes	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT,HEAT_2,Pro_isomerase
WH2_k127_3050411_0	926562.Oweho_2220	2.229e-141	453.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1HXY4@117743|Flavobacteriia,2PABR@246874|Cryomorphaceae	976|Bacteroidetes	J	PFAM tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
WH2_k127_3088237_3	1550091.JROE01000004_gene1306	1.209e-18	90.0	COG0073@1|root,COG0073@2|Bacteria,4NQ9I@976|Bacteroidetes,1ISRQ@117747|Sphingobacteriia	976|Bacteroidetes	J	Export-related chaperone CsaA	csaA	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
WH2_k127_3088237_0	755732.Fluta_1927	1.45e-105	351.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
WH2_k127_3088237_1	509635.N824_17220	5.649e-48	174.0	COG0346@1|root,COG0346@2|Bacteria,4NNNG@976|Bacteroidetes	976|Bacteroidetes	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WH2_k127_3090759_1	627192.SLG_30810	3.18e-13	73.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,2TRU4@28211|Alphaproteobacteria,2K02W@204457|Sphingomonadales	204457|Sphingomonadales	O	peptidase M13	-	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
WH2_k127_3090759_0	391587.KAOT1_12767	1.265e-36	156.0	COG1345@1|root,COG3291@1|root,COG1345@2|Bacteria,COG3291@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia	976|Bacteroidetes	N	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	CUB,LTD,fn3
WH2_k127_3125037_0	866536.Belba_3226	2.48e-186	586.0	COG3278@1|root,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,47JV6@768503|Cytophagia	976|Bacteroidetes	C	PFAM Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
WH2_k127_3125037_1	746697.Aeqsu_0131	7.827e-113	374.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,4NEM7@976|Bacteroidetes,1HWV2@117743|Flavobacteriia	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit II	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrom_C,Cytochrome_CBB3,FixO
WH2_k127_3125037_5	929713.NIASO_20605	1.614e-19	93.0	2E58U@1|root,33018@2|Bacteria,4NVWZ@976|Bacteroidetes,1IZ66@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3125037_2	886377.Murru_2639	2.19e-58	206.0	COG2010@1|root,COG2010@2|Bacteria,4NQNG@976|Bacteroidetes,1I3H8@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3125037_3	1313301.AUGC01000013_gene1255	3.295e-39	153.0	COG2346@1|root,COG2346@2|Bacteria,4NQCV@976|Bacteroidetes	976|Bacteroidetes	S	Pfam Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
WH2_k127_3125037_4	649349.Lbys_0337	1.106e-37	146.0	2E3RQ@1|root,32YPC@2|Bacteria,4NRGB@976|Bacteroidetes,47RQ7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3125037_6	521097.Coch_1338	2.508e-15	77.0	COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,1HXS5@117743|Flavobacteriia,1EQQF@1016|Capnocytophaga	976|Bacteroidetes	C	Di-iron-containing protein involved in the repair of iron-sulfur clusters	ric	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
WH2_k127_3142839_3	880526.KE386488_gene86	4.299e-54	204.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,2FP2A@200643|Bacteroidia,22UBX@171550|Rikenellaceae	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
WH2_k127_3142839_6	745718.JADT01000013_gene1273	2.16e-16	83.0	2E46C@1|root,32Z2A@2|Bacteria,4NV81@976|Bacteroidetes,1I537@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3142839_4	1453500.AT05_05045	1.167e-21	102.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1HX34@117743|Flavobacteriia	976|Bacteroidetes	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
WH2_k127_3142839_0	760192.Halhy_4320	5.937e-234	752.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1IQXN@117747|Sphingobacteriia	976|Bacteroidetes	CO	Cytochrome c biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
WH2_k127_3142839_2	1121957.ATVL01000010_gene576	3.575e-77	263.0	COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,47KZ6@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
WH2_k127_3142839_1	929556.Solca_3990	2.94e-231	725.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1INNX@117747|Sphingobacteriia	976|Bacteroidetes	O	chelatase, subunit chli	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WH2_k127_3142839_8	926556.Echvi_3891	0.0007138	50.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
WH2_k127_3142839_5	1122931.AUAE01000005_gene3236	3.846e-17	90.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,2FPKW@200643|Bacteroidia,22XTD@171551|Porphyromonadaceae	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WH2_k127_3142839_7	203275.BFO_3042	4.961e-12	69.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,2FMVF@200643|Bacteroidia,22WWV@171551|Porphyromonadaceae	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WH2_k127_31729_2	1288963.ADIS_0868	6.021e-05	54.0	COG1575@1|root,COG1575@2|Bacteria,4NGCJ@976|Bacteroidetes,47JDA@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
WH2_k127_31729_0	1121129.KB903360_gene3345	2.954e-149	479.0	COG0447@1|root,COG0447@2|Bacteria,4NDXT@976|Bacteroidetes,2FMME@200643|Bacteroidia,22VYD@171551|Porphyromonadaceae	976|Bacteroidetes	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WH2_k127_31729_1	1168289.AJKI01000018_gene2003	1.66e-57	208.0	COG1165@1|root,COG1165@2|Bacteria,4NETZ@976|Bacteroidetes,2FMSK@200643|Bacteroidia,3XISC@558415|Marinilabiliaceae	976|Bacteroidetes	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
WH2_k127_3181776_0	869213.JCM21142_31266	1.759e-139	451.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,47JRD@768503|Cytophagia	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
WH2_k127_3181776_1	485917.Phep_0623	1.69e-102	340.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,1IP59@117747|Sphingobacteriia	976|Bacteroidetes	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WH2_k127_3181776_2	509635.N824_07265	1.685e-17	82.0	COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,1IT95@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
WH2_k127_3182332_3	357808.RoseRS_2786	4.407e-39	159.0	COG1520@1|root,COG1520@2|Bacteria,2G9GE@200795|Chloroflexi,3774I@32061|Chloroflexia	32061|Chloroflexia	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3182332_4	1123368.AUIS01000011_gene1139	7.698e-25	122.0	COG1404@1|root,COG1404@2|Bacteria,1R90Q@1224|Proteobacteria,1S01H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
WH2_k127_3182332_0	1305737.JAFX01000001_gene3553	1.336e-184	588.0	COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,47JY2@768503|Cytophagia	976|Bacteroidetes	E	PFAM Cys Met metabolism PLP-dependent enzyme	metC	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
WH2_k127_3182332_1	1408433.JHXV01000016_gene1824	6.813e-153	508.0	COG3291@1|root,COG3291@2|Bacteria,4NJK3@976|Bacteroidetes,1I16K@117743|Flavobacteriia,2PC6D@246874|Cryomorphaceae	976|Bacteroidetes	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43
WH2_k127_3182332_6	869213.JCM21142_3965	3.381e-12	73.0	2DXS6@1|root,34692@2|Bacteria,4P5EX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3182332_2	927658.AJUM01000047_gene2831	6.458e-52	196.0	29N3N@1|root,32D2M@2|Bacteria,4NRTM@976|Bacteroidetes,2G223@200643|Bacteroidia,3XJ24@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3182332_5	1123035.ARLA01000028_gene2386	4.696e-20	90.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia,4C37M@83612|Psychroflexus	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WH2_k127_3183731_1	1122176.KB903576_gene5010	1.027e-22	103.0	COG2133@1|root,COG4886@1|root,COG2133@2|Bacteria,COG4886@2|Bacteria,4NF0B@976|Bacteroidetes,1IVY8@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
WH2_k127_3183731_0	755732.Fluta_0526	1.196e-231	728.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,1HY71@117743|Flavobacteriia,2PAMI@246874|Cryomorphaceae	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
WH2_k127_3186764_0	1166018.FAES_5299	2.673e-231	738.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,4NF3R@976|Bacteroidetes,47N7W@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4,Peptidase_M1
WH2_k127_3194817_0	1453500.AT05_00665	3.204e-163	518.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1HWSA@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
WH2_k127_3194817_1	1408433.JHXV01000004_gene3388	8.777e-150	502.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,1I54C@117743|Flavobacteriia,2PAIC@246874|Cryomorphaceae	976|Bacteroidetes	Q	PFAM FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
WH2_k127_3194817_2	1408473.JHXO01000010_gene3507	4.611e-78	285.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WH2_k127_3196870_0	1122176.KB903546_gene1027	1.281e-43	176.0	COG0265@1|root,COG3291@1|root,COG0265@2|Bacteria,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes	976|Bacteroidetes	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,MAM,UnbV_ASPIC,VCBS,fn3
WH2_k127_3196870_2	675812.VHA_002952	1.061e-19	98.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,1XTIB@135623|Vibrionales	135623|Vibrionales	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
WH2_k127_3196870_1	1089547.KB913013_gene3832	4.118e-41	162.0	COG0730@1|root,COG0730@2|Bacteria,4NIJ9@976|Bacteroidetes,47P8A@768503|Cytophagia	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WH2_k127_3200889_0	743722.Sph21_2092	6.628e-53	197.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPAI@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,CarboxypepD_reg,OmpA,PD40
WH2_k127_3200889_2	553171.HMPREF0648_1422	1.895e-05	57.0	28IAZ@1|root,2Z8DG@2|Bacteria,4NH0A@976|Bacteroidetes,2FWGK@200643|Bacteroidia	976|Bacteroidetes	S	DNA-sulfur modification-associated	-	-	-	-	-	-	-	-	-	-	-	-	DndB
WH2_k127_3200889_1	1121904.ARBP01000006_gene3848	2.743e-13	79.0	2EMGK@1|root,33F59@2|Bacteria,4NYBS@976|Bacteroidetes,47T7T@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3200889_3	374847.Kcr_0638	0.0001824	51.0	arCOG02559@1|root,arCOG02559@2157|Archaea	2157|Archaea	P	by modhmm	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
WH2_k127_3202626_1	643867.Ftrac_3154	8.619e-26	110.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,47MUX@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
WH2_k127_3202626_0	755732.Fluta_2899	2.249e-51	205.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2PBEH@246874|Cryomorphaceae	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
WH2_k127_3202980_0	1121898.Q766_05980	2.489e-113	385.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,2NSCF@237|Flavobacterium	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,SprB
WH2_k127_3207065_0	1317122.ATO12_01065	0.0	1066.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia,2YGYJ@290174|Aquimarina	976|Bacteroidetes	L	DNA Topoisomerase IV	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
WH2_k127_3227928_2	700598.Niako_3009	1.801e-30	136.0	COG0454@1|root,COG0456@2|Bacteria,4NQVT@976|Bacteroidetes,1ISRI@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	paiA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
WH2_k127_3227928_0	1120965.AUBV01000007_gene2564	2.21e-136	446.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,47NRU@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WH2_k127_3227928_1	1121957.ATVL01000009_gene1378	4.831e-53	188.0	COG2148@1|root,COG2148@2|Bacteria,4NFIA@976|Bacteroidetes,47XQ7@768503|Cytophagia	976|Bacteroidetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
WH2_k127_3237219_1	1123276.KB893290_gene5205	2.733e-30	138.0	COG1577@1|root,COG1874@1|root,COG2374@1|root,COG2706@1|root,COG4625@1|root,COG4886@1|root,COG1577@2|Bacteria,COG1874@2|Bacteria,COG2374@2|Bacteria,COG2706@2|Bacteria,COG4625@2|Bacteria,COG4886@2|Bacteria,4NI5S@976|Bacteroidetes,47THH@768503|Cytophagia	976|Bacteroidetes	G	Dystroglycan-type cadherin-like domains.	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_5,Calx-beta,Exo_endo_phos,He_PIG,LTD,VCBS
WH2_k127_3237219_2	1089547.KB913013_gene2083	6.509e-25	108.0	COG3118@1|root,COG3118@2|Bacteria,4NSE6@976|Bacteroidetes,47R3Q@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM bacillithiol system protein YtxJ	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
WH2_k127_3237219_0	926562.Oweho_1440	2.938e-106	353.0	COG0507@1|root,COG0507@2|Bacteria,4NF6J@976|Bacteroidetes,1HZ14@117743|Flavobacteriia,2PAXQ@246874|Cryomorphaceae	976|Bacteroidetes	L	COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	HTH_40,Herpes_Helicase,PIF1,UvrD_C_2
WH2_k127_3275044_1	1267534.KB906757_gene1105	1.737e-06	56.0	COG1629@1|root,COG1629@2|Bacteria,3Y2N1@57723|Acidobacteria,2JIIP@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
WH2_k127_3275044_0	755732.Fluta_1579	2.967e-40	154.0	COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,1HWQF@117743|Flavobacteriia,2PADY@246874|Cryomorphaceae	976|Bacteroidetes	S	Membrane protein involved in the export of O-antigen and teichoic acid	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
WH2_k127_3283100_2	1300345.LF41_2471	1.286e-20	94.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,1X6UH@135614|Xanthomonadales	135614|Xanthomonadales	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK2	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
WH2_k127_3283100_0	313594.PI23P_02642	4.991e-50	189.0	COG0801@1|root,COG1428@1|root,COG0801@2|Bacteria,COG1428@2|Bacteria,4NGE8@976|Bacteroidetes,1HWTH@117743|Flavobacteriia,3VWA9@52959|Polaribacter	976|Bacteroidetes	FH	Thymidylate kinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
WH2_k127_3283100_1	886379.AEWI01000122_gene1857	2.362e-32	139.0	COG5010@1|root,COG5010@2|Bacteria,4PMJW@976|Bacteroidetes,2G0E2@200643|Bacteroidia,3XJQR@558415|Marinilabiliaceae	976|Bacteroidetes	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
WH2_k127_3288090_0	269798.CHU_2796	9.16e-140	465.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47NFW@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	pgtB	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA
WH2_k127_3289106_1	926562.Oweho_1212	9.722e-70	244.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1HX2V@117743|Flavobacteriia,2PABS@246874|Cryomorphaceae	976|Bacteroidetes	E	Aromatic amino acid lyase	hutH	-	4.3.1.23,4.3.1.3	ko:K01745,ko:K10774	ko00340,ko00350,ko01100,map00340,map00350,map01100	M00045	R00737,R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
WH2_k127_3289106_0	269798.CHU_2108	2.318e-87	317.0	COG4106@1|root,COG4258@1|root,COG4106@2|Bacteria,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,47P2T@768503|Cytophagia	976|Bacteroidetes	I	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
WH2_k127_3334115_3	1121939.L861_13870	1.144e-32	129.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XH3S@135619|Oceanospirillales	135619|Oceanospirillales	G	TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
WH2_k127_3334115_1	1270196.JCKI01000001_gene3847	4.415e-62	219.0	COG0306@1|root,COG0306@2|Bacteria,4NE7J@976|Bacteroidetes,1IPR3@117747|Sphingobacteriia	976|Bacteroidetes	P	phosphate transporter	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
WH2_k127_3334115_2	700598.Niako_6887	2.547e-54	198.0	COG1392@1|root,COG1392@2|Bacteria,4NI25@976|Bacteroidetes,1INNB@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1392 Phosphate transport regulator (distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
WH2_k127_3334115_0	1122176.KB903539_gene1393	2.717e-89	299.0	COG0663@1|root,COG0663@2|Bacteria,4NG5P@976|Bacteroidetes,1IVF8@117747|Sphingobacteriia	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	paaY	-	-	ko:K02617,ko:K08279	-	-	-	-	ko00000	-	-	-	Hexapep
WH2_k127_3334115_5	1123242.JH636436_gene553	1.591e-26	116.0	2E3V1@1|root,32YSA@2|Bacteria,2J1BP@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3334115_4	1239962.C943_00200	5.215e-30	124.0	COG3169@1|root,COG3169@2|Bacteria,4NQH4@976|Bacteroidetes,47QJ9@768503|Cytophagia	976|Bacteroidetes	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
WH2_k127_3339063_2	1121920.AUAU01000004_gene583	7.461e-22	102.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,3Y3YU@57723|Acidobacteria	57723|Acidobacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,Y_Y_Y
WH2_k127_3339063_1	755732.Fluta_1076	4.05e-48	182.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1ICNV@117743|Flavobacteriia,2PBDQ@246874|Cryomorphaceae	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
WH2_k127_3339063_0	755732.Fluta_1076	6.151e-77	268.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1ICNV@117743|Flavobacteriia,2PBDQ@246874|Cryomorphaceae	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
WH2_k127_3343911_0	760192.Halhy_5400	3.113e-221	702.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1IQQY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S9, prolyl oligopeptidase, catalytic domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
WH2_k127_3364500_0	1122973.KB904239_gene495	1.148e-236	749.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,22W1K@171551|Porphyromonadaceae	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WH2_k127_3374453_0	1408433.JHXV01000019_gene1924	5.985e-100	331.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1HWQN@117743|Flavobacteriia,2PAIQ@246874|Cryomorphaceae	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
WH2_k127_3374453_2	933262.AXAM01000018_gene985	4.518e-12	76.0	2E6MH@1|root,33183@2|Bacteria,1NDAB@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
WH2_k127_3374453_3	933262.AXAM01000018_gene986	1.145e-09	64.0	2EIHU@1|root,33C96@2|Bacteria,1NJTC@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
WH2_k127_3374453_1	518766.Rmar_0903	5.169e-27	117.0	COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,1FIV8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	Outer membrane efflux protein	tolC	-	-	-	-	-	-	-	-	-	-	-	OEP
WH2_k127_3391812_0	1122176.KB903551_gene4274	7.369e-142	468.0	COG3227@1|root,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	3.2.1.14	ko:K01183,ko:K20274	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000,ko01002	-	GH18	-	Big_3,ChW,DUF5011,Flg_new,PCMD,Peptidase_M43
WH2_k127_3402761_0	761193.Runsl_1396	3.632e-142	460.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,47MVE@768503|Cytophagia	976|Bacteroidetes	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
WH2_k127_3402761_1	1121373.KB903630_gene306	4.098e-36	141.0	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,47QN0@768503|Cytophagia	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
WH2_k127_3405692_0	1408433.JHXV01000010_gene528	3.613e-39	147.0	COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,1I1YF@117743|Flavobacteriia,2PB2E@246874|Cryomorphaceae	976|Bacteroidetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
WH2_k127_3405692_1	439235.Dalk_2897	1.447e-15	90.0	COG5184@1|root,COG5276@1|root,COG5184@2|Bacteria,COG5276@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
WH2_k127_3406433_1	755732.Fluta_1314	4.8e-42	169.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
WH2_k127_3406433_0	1250006.JHZZ01000001_gene238	2.854e-63	239.0	COG2133@1|root,COG3568@1|root,COG5492@1|root,COG2133@2|Bacteria,COG3568@2|Bacteria,COG5492@2|Bacteria,4NPDY@976|Bacteroidetes,1I1DH@117743|Flavobacteriia,3VXGV@52959|Polaribacter	976|Bacteroidetes	GN	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3406666_0	1288963.ADIS_4600	2.561e-110	364.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47K19@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
WH2_k127_3406666_2	1239962.C943_03895	8.997e-55	216.0	COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes,47NYC@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
WH2_k127_3406666_1	1267211.KI669560_gene840	1.256e-78	280.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1INS3@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WH2_k127_3406666_3	1341155.FSS13T_01680	3.781e-06	49.0	2BFVS@1|root,329R5@2|Bacteria,4NSXJ@976|Bacteroidetes,1I43Y@117743|Flavobacteriia,2NXPZ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3417369_3	1537915.JU57_09430	5.123e-16	80.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,42MYK@68525|delta/epsilon subdivisions,2YMMB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WH2_k127_3417369_1	1356852.N008_09910	6.709e-40	154.0	COG1765@1|root,COG1765@2|Bacteria,4NQ66@976|Bacteroidetes,47QCI@768503|Cytophagia	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	osmC	-	-	-	-	-	-	-	-	-	-	-	OsmC
WH2_k127_3417369_2	1313301.AUGC01000005_gene307	3.39e-30	130.0	28MPU@1|root,2ZAYW@2|Bacteria,4NRQD@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3417369_0	755732.Fluta_2251	3.794e-123	399.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,1HXXW@117743|Flavobacteriia,2PADK@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
WH2_k127_3434441_2	1168034.FH5T_01405	1.328e-31	124.0	COG2184@1|root,COG2184@2|Bacteria,4NID4@976|Bacteroidetes,2FQ83@200643|Bacteroidia	976|Bacteroidetes	D	FIC family	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Bro-N,Fic
WH2_k127_3434441_0	1453500.AT05_04485	1.556e-41	167.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,fn3
WH2_k127_3434441_1	398720.MED217_02450	6.159e-38	151.0	COG1327@1|root,COG1327@2|Bacteria,4NHXI@976|Bacteroidetes,1HYJ8@117743|Flavobacteriia	976|Bacteroidetes	K	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	ATP-cone,Mrr_cat
WH2_k127_3451918_3	1408433.JHXV01000005_gene2237	1.969e-33	132.0	2ENP2@1|root,33GAE@2|Bacteria,4NZIT@976|Bacteroidetes,1I8VS@117743|Flavobacteriia,2PB29@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3451918_0	1408433.JHXV01000005_gene2236	3.188e-103	347.0	COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,1HXBB@117743|Flavobacteriia,2PADX@246874|Cryomorphaceae	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
WH2_k127_3451918_2	1203611.KB894541_gene1581	1.231e-42	161.0	COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,2FR57@200643|Bacteroidia,22UHI@171550|Rikenellaceae	976|Bacteroidetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
WH2_k127_3451918_1	926562.Oweho_1099	2.185e-96	325.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1HYPM@117743|Flavobacteriia,2PABU@246874|Cryomorphaceae	976|Bacteroidetes	D	PFAM Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WH2_k127_3451918_4	709991.Odosp_2293	1.032e-07	61.0	COG0457@1|root,COG0457@2|Bacteria,4P45T@976|Bacteroidetes,2FYEG@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3460162_0	91464.S7335_4589	1.477e-114	382.0	COG0415@1|root,COG0415@2|Bacteria,1G1HV@1117|Cyanobacteria,1H01F@1129|Synechococcus	1117|Cyanobacteria	L	Belongs to the DNA photolyase family	cry	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
WH2_k127_3460162_1	1305737.JAFX01000001_gene2866	3.304e-92	306.0	COG3046@1|root,COG3046@2|Bacteria,4NECD@976|Bacteroidetes,47N6N@768503|Cytophagia	976|Bacteroidetes	S	Deoxyribodipyrimidine photo-lyase-related protein	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP,FAD_binding_7
WH2_k127_3466672_1	1296416.JACB01000054_gene3780	2.048e-69	241.0	COG1225@1|root,COG1225@2|Bacteria,4NEEA@976|Bacteroidetes,1HY6E@117743|Flavobacteriia,2YJAQ@290174|Aquimarina	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
WH2_k127_3466672_0	926549.KI421517_gene2227	5.508e-104	346.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47M5P@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
WH2_k127_3498121_3	1550091.JROE01000005_gene2132	1.829e-08	67.0	COG2834@1|root,COG2834@2|Bacteria,4NFYQ@976|Bacteroidetes,1ISUD@117747|Sphingobacteriia	976|Bacteroidetes	M	Domain of unknown function (DUF4292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
WH2_k127_3498121_1	468059.AUHA01000002_gene1188	6.991e-100	349.0	COG0457@1|root,COG0457@2|Bacteria,4NDVW@976|Bacteroidetes,1IR0N@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
WH2_k127_3498121_0	1227739.Hsw_3730	1.506e-122	402.0	COG1208@1|root,COG1208@2|Bacteria,4NE97@976|Bacteroidetes,47ND5@768503|Cytophagia	976|Bacteroidetes	JM	Nucleotidyl transferase	rffH	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
WH2_k127_3498121_2	1349822.NSB1T_03830	2.729e-58	205.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,2FR7A@200643|Bacteroidia,22XVH@171551|Porphyromonadaceae	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
WH2_k127_3503689_0	984262.SGRA_3409	5.798e-60	222.0	COG0657@1|root,COG0657@2|Bacteria,4NNWF@976|Bacteroidetes,1ITB7@117747|Sphingobacteriia	976|Bacteroidetes	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase,Lipase_GDSL_2,Peptidase_S9
WH2_k127_3507589_1	313606.M23134_02261	3.692e-39	153.0	COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,47Q99@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
WH2_k127_3507589_0	755732.Fluta_0001	5.927e-255	791.0	COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,1HX45@117743|Flavobacteriia,2PAFX@246874|Cryomorphaceae	976|Bacteroidetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
WH2_k127_3520028_3	1296416.JACB01000029_gene4180	9.749e-21	98.0	COG0265@1|root,COG0265@2|Bacteria,4PKT1@976|Bacteroidetes,1I89F@117743|Flavobacteriia,2YGTW@290174|Aquimarina	976|Bacteroidetes	O	Trypsin-like peptidase domain	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2,fn3
WH2_k127_3520028_1	1356852.N008_11205	6.471e-63	225.0	COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,47XHY@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
WH2_k127_3520028_0	1227739.Hsw_3630	3.539e-82	284.0	COG0859@1|root,COG0859@2|Bacteria,4NMIH@976|Bacteroidetes,47MIW@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
WH2_k127_3520028_2	1408433.JHXV01000040_gene1522	5.88e-37	154.0	COG3307@1|root,COG3307@2|Bacteria,4PBYP@976|Bacteroidetes,1IMS1@117743|Flavobacteriia,2PBUF@246874|Cryomorphaceae	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WH2_k127_3531428_0	504472.Slin_0829	1.607e-111	365.0	COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,47KN6@768503|Cytophagia	976|Bacteroidetes	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WH2_k127_3531428_1	1515615.HQ41_03165	2.088e-59	210.0	2CJ2T@1|root,32S93@2|Bacteria,4NXHM@976|Bacteroidetes,2FZ2F@200643|Bacteroidia,230Y3@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3531428_3	338963.Pcar_0670	7.45e-06	54.0	COG0551@1|root,COG0551@2|Bacteria,1RCA8@1224|Proteobacteria,42R20@68525|delta/epsilon subdivisions,2WN67@28221|Deltaproteobacteria,43SKQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WH2_k127_3531428_2	1123400.KB904765_gene1396	2.189e-41	164.0	COG0823@1|root,COG1361@1|root,COG2706@1|root,COG2834@1|root,COG3291@1|root,COG5384@1|root,COG0823@2|Bacteria,COG1361@2|Bacteria,COG2706@2|Bacteria,COG2834@2|Bacteria,COG3291@2|Bacteria,COG5384@2|Bacteria,1QUSE@1224|Proteobacteria	1224|Proteobacteria	G	PFAM FecR protein	-	-	3.2.1.4	ko:K01179,ko:K03933	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	AA10,CBM73,GH5,GH9	-	CBM_2,Calx-beta,Cellulase,PKD
WH2_k127_3564236_1	1408433.JHXV01000026_gene3026	1.625e-132	440.0	COG0419@1|root,COG0823@1|root,COG0419@2|Bacteria,COG0823@2|Bacteria,4P15I@976|Bacteroidetes,1IE72@117743|Flavobacteriia,2PBDD@246874|Cryomorphaceae	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
WH2_k127_3564236_0	926562.Oweho_0996	5.177e-164	527.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1HWW8@117743|Flavobacteriia,2PA51@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM 2-oxoacid dehydrogenases acyltransferase (catalytic domain)	bfmBB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WH2_k127_3564236_2	1122176.KB903538_gene1506	2.672e-34	143.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,1IV9F@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2
WH2_k127_3568279_3	1211115.ALIQ01000164_gene3404	3.728e-09	63.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,3NA7M@45404|Beijerinckiaceae	28211|Alphaproteobacteria	L	helicase superfamily c-terminal domain	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
WH2_k127_3568279_0	1515615.HQ41_06750	2.371e-135	439.0	COG0330@1|root,COG0330@2|Bacteria,4NH8V@976|Bacteroidetes,2FQPC@200643|Bacteroidia,22Z0Q@171551|Porphyromonadaceae	976|Bacteroidetes	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WH2_k127_3568279_2	879243.Poras_0910	2.022e-20	100.0	COG1585@1|root,COG1585@2|Bacteria,4NY97@976|Bacteroidetes,2FZWH@200643|Bacteroidia	976|Bacteroidetes	OU	Membrane protein implicated in regulation of membrane protease activity	nfeD	-	-	-	-	-	-	-	-	-	-	-	NfeD
WH2_k127_3568279_4	158189.SpiBuddy_0375	1.421e-08	68.0	2FCS9@1|root,344VD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
WH2_k127_3568279_1	1121438.JNJA01000011_gene1834	1.055e-108	380.0	COG0463@1|root,COG0463@2|Bacteria,1QTWH@1224|Proteobacteria,43CTF@68525|delta/epsilon subdivisions,2X80Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH2_k127_3575579_0	755732.Fluta_0797	2.966e-75	273.0	COG2208@1|root,COG2208@2|Bacteria,4NHV8@976|Bacteroidetes	976|Bacteroidetes	KT	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,SpoIIE
WH2_k127_3575579_1	925409.KI911562_gene1048	5.534e-30	121.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,1IZ5W@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase beta subunit	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WH2_k127_3576077_0	1123277.KB893173_gene1655	9.535e-46	170.0	COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,47N4G@768503|Cytophagia	976|Bacteroidetes	H	PFAM Tetrapyrrole (Corrin Porphyrin) Methylases	rsmI_1	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
WH2_k127_3576077_1	761193.Runsl_0219	1.111e-26	125.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,47K12@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
WH2_k127_3576077_2	84751.XP_007876561.1	4.47e-09	64.0	COG0545@1|root,KOG0544@2759|Eukaryota,3A3EV@33154|Opisthokonta,3P4BA@4751|Fungi,3V1MQ@5204|Basidiomycota,3N1EU@452284|Ustilaginomycotina	4751|Fungi	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005527,GO:0005528,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0023052,GO:0031929,GO:0035556,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0061077,GO:0065007,GO:0071704,GO:0097159,GO:0140096,GO:1901363,GO:1901564	5.2.1.8	ko:K09568	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
WH2_k127_3576329_2	1155718.KB891855_gene39	0.0003596	53.0	COG0457@1|root,COG0457@2|Bacteria,2GK6N@201174|Actinobacteria	201174|Actinobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_12,TPR_7
WH2_k127_3576329_1	1444770.AF72_04165	2.861e-36	155.0	COG3142@1|root,COG3142@2|Bacteria,1MV5W@1224|Proteobacteria,1RMC1@1236|Gammaproteobacteria,1XCQ4@135614|Xanthomonadales	135614|Xanthomonadales	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
WH2_k127_3576329_0	1506583.JQJY01000008_gene4049	3.07e-68	244.0	COG3250@1|root,COG3250@2|Bacteria,4NE7H@976|Bacteroidetes,1HX95@117743|Flavobacteriia,2NTHP@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
WH2_k127_3580772_0	742817.HMPREF9449_01458	5.001e-06	59.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,2FQU9@200643|Bacteroidia,22W8U@171551|Porphyromonadaceae	976|Bacteroidetes	G	Domain of unknown function (DUF5110)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,F5_F8_type_C,Gal_mutarotas_2,Glyco_hydro_31,fn3
WH2_k127_3584929_0	1278073.MYSTI_05798	2.557e-61	231.0	2DBDJ@1|root,2Z8ME@2|Bacteria	2|Bacteria	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
WH2_k127_3605884_0	1089547.KB913013_gene319	7.702e-60	212.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,47KCT@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
WH2_k127_3605884_1	694427.Palpr_2753	1.736e-19	94.0	COG1238@1|root,COG1238@2|Bacteria,4NQAX@976|Bacteroidetes,2FRY9@200643|Bacteroidia,22Y6T@171551|Porphyromonadaceae	976|Bacteroidetes	S	membrane	yqaA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
WH2_k127_3605884_2	1283299.AUKG01000006_gene774	5.443e-10	70.0	COG3693@1|root,COG3693@2|Bacteria	2|Bacteria	G	endo-1,4-beta-xylanase activity	abfB	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_62,RicinB_lectin_2,Ricin_B_lectin
WH2_k127_3606575_4	1341181.FLJC2902T_18190	3.228e-25	108.0	COG0346@1|root,COG0346@2|Bacteria,4NQK6@976|Bacteroidetes,1I4MY@117743|Flavobacteriia,2NWKI@237|Flavobacterium	976|Bacteroidetes	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_2
WH2_k127_3606575_3	572480.Arnit_1986	1.697e-33	138.0	COG1917@1|root,COG1917@2|Bacteria,1RGXQ@1224|Proteobacteria,42TGE@68525|delta/epsilon subdivisions,2YSAD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3606575_0	1313301.AUGC01000005_gene273	1.607e-148	479.0	COG1454@1|root,COG1454@2|Bacteria,4PKHV@976|Bacteroidetes	976|Bacteroidetes	C	alcohol dehydrogenase	-	-	1.1.3.48	ko:K19714	-	-	R11394	RC03427	ko00000,ko01000,ko01005	-	-	-	Fe-ADH
WH2_k127_3606575_2	1313301.AUGC01000006_gene129	1.964e-39	151.0	2CNQU@1|root,32SHJ@2|Bacteria,4NSMZ@976|Bacteroidetes	976|Bacteroidetes	S	DoxX family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
WH2_k127_3606575_1	1403819.BATR01000066_gene1947	6.758e-50	182.0	COG1943@1|root,COG1943@2|Bacteria,46VP6@74201|Verrucomicrobia,2IVSQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WH2_k127_3608879_1	313596.RB2501_11852	3.844e-44	169.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,4NERC@976|Bacteroidetes,1HWT4@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,MerR_1
WH2_k127_3608879_2	709991.Odosp_1463	1.042e-12	80.0	COG2849@1|root,COG2849@2|Bacteria,4NJB4@976|Bacteroidetes,2FPI4@200643|Bacteroidia,22Z5V@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function (DUF3352)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352,MORN_2
WH2_k127_3608879_0	1121898.Q766_13060	2.049e-73	250.0	COG0277@1|root,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1HXIK@117743|Flavobacteriia,2NSEK@237|Flavobacterium	976|Bacteroidetes	C	Dehydrogenase	glcD	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
WH2_k127_361490_1	1379270.AUXF01000002_gene1561	7.111e-49	177.0	COG0393@1|root,COG0393@2|Bacteria,1ZU21@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
WH2_k127_361490_0	379066.GAU_1081	5.104e-192	607.0	COG0673@1|root,COG0673@2|Bacteria,1ZSVT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WH2_k127_361490_2	379066.GAU_1078	2.753e-07	52.0	2CISN@1|root,2Z7MB@2|Bacteria,1ZU2Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
WH2_k127_3627474_0	398579.Spea_4149	0.0008917	49.0	COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,1P5IH@1224|Proteobacteria,1RPYC@1236|Gammaproteobacteria,2Q8XN@267890|Shewanellaceae	1236|Gammaproteobacteria	O	peptidase M6 immune inhibitor A	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PKD,Peptidase_M6
WH2_k127_3658357_3	1313421.JHBV01000027_gene1790	1.749e-09	66.0	2CGN1@1|root,3348T@2|Bacteria,4NX4E@976|Bacteroidetes,1IUF2@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3658357_0	468059.AUHA01000002_gene248	2.389e-209	661.0	COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,1INYG@117747|Sphingobacteriia	976|Bacteroidetes	IQ	PFAM GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
WH2_k127_3658357_2	1408473.JHXO01000001_gene1998	1.309e-69	244.0	2BVTQ@1|root,2Z7J9@2|Bacteria,4NGSY@976|Bacteroidetes,2FWJ5@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF2797)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2797
WH2_k127_3658357_1	1122621.ATZA01000037_gene3506	1.253e-109	367.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,1IP6H@117747|Sphingobacteriia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
WH2_k127_3671236_0	1279009.ADICEAN_00356	2.07e-154	502.0	COG0189@1|root,COG0189@2|Bacteria,4NF2R@976|Bacteroidetes,47P1C@768503|Cytophagia	976|Bacteroidetes	HJ	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
WH2_k127_3671236_1	886379.AEWI01000139_gene2240	4.948e-22	98.0	COG3271@1|root,COG3271@2|Bacteria,4NN8E@976|Bacteroidetes,2G23E@200643|Bacteroidia,3XJE1@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
WH2_k127_3672936_4	1121403.AUCV01000005_gene232	5.611e-11	74.0	COG0655@1|root,COG0655@2|Bacteria,1RD5X@1224|Proteobacteria,42T3S@68525|delta/epsilon subdivisions,2WN9W@28221|Deltaproteobacteria,2MPTA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
WH2_k127_3672936_1	649349.Lbys_2286	6.602e-66	244.0	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,47MWN@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
WH2_k127_3672936_2	1121898.Q766_20605	5.874e-49	187.0	COG4589@1|root,COG4589@2|Bacteria,4NIPM@976|Bacteroidetes,1HXPT@117743|Flavobacteriia,2NS7C@237|Flavobacterium	976|Bacteroidetes	S	Phosphatidate cytidylyltransferase	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
WH2_k127_3672936_5	866536.Belba_1246	0.0009538	45.0	2EGF5@1|root,33A75@2|Bacteria,4NY8Y@976|Bacteroidetes,47SZX@768503|Cytophagia	976|Bacteroidetes	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
WH2_k127_3672936_0	926562.Oweho_1567	1.106e-266	836.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1HXSC@117743|Flavobacteriia,2PA4Q@246874|Cryomorphaceae	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
WH2_k127_3672936_3	1550091.JROE01000004_gene1693	6.976e-36	139.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,1ISS0@117747|Sphingobacteriia	976|Bacteroidetes	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
WH2_k127_3678408_1	945713.IALB_0147	8.9e-42	163.0	COG2234@1|root,COG4412@1|root,COG2234@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.11.10,3.4.21.50	ko:K01337,ko:K05994,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF4968,DUF5110,F5_F8_type_C,Glyco_hydro_31,PA,Peptidase_M28,Peptidase_M6,Peptidase_S8,W_rich_C
WH2_k127_3678408_2	755732.Fluta_0626	5.56e-14	80.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460,F5_F8_type_C,Glyco_hydro_98C,Glyco_hydro_98M
WH2_k127_3678408_0	883096.HMPREF9699_00741	1.937e-99	328.0	COG1506@1|root,COG1506@2|Bacteria,4NF7I@976|Bacteroidetes,1HXW2@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase	ptpA	-	3.4.14.12,3.4.14.5	ko:K01278,ko:K18574	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
WH2_k127_3688338_2	502025.Hoch_3520	4.951e-64	227.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2YWC8@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH2_k127_3688338_0	1408473.JHXO01000010_gene3698	9.97e-126	422.0	COG0577@1|root,COG0577@2|Bacteria,4NFUG@976|Bacteroidetes,2FM5B@200643|Bacteroidia	976|Bacteroidetes	V	Efflux ABC transporter, permease protein	macB_3	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH2_k127_3688338_1	926562.Oweho_3327	8.634e-103	343.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1HXN4@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
WH2_k127_3696893_2	929703.KE386491_gene1798	1.034e-39	157.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,47MQZ@768503|Cytophagia	976|Bacteroidetes	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WH2_k127_3696893_3	649638.Trad_2729	0.0006907	48.0	COG0457@1|root,COG0457@2|Bacteria,1WJ9W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8
WH2_k127_3696893_1	742725.HMPREF9450_02169	4.294e-40	161.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,2FNMS@200643|Bacteroidia,22US3@171550|Rikenellaceae	976|Bacteroidetes	U	Signal peptidase I	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
WH2_k127_3696893_0	706436.HMPREF9074_09183	1.395e-51	184.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1HY4X@117743|Flavobacteriia,1ERC3@1016|Capnocytophaga	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
WH2_k127_3698890_0	1089547.KB913013_gene2913	3.33e-61	215.0	28NIX@1|root,2ZBK6@2|Bacteria,4NMEI@976|Bacteroidetes,47MBS@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2480)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2480
WH2_k127_3698890_1	1127673.GLIP_0370	1.693e-09	66.0	COG2911@1|root,COG4733@1|root,COG2911@2|Bacteria,COG4733@2|Bacteria,1P8N9@1224|Proteobacteria,1SCTK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,DUF5122,He_PIG,OmpA_membrane
WH2_k127_3709885_1	1197477.IA57_11060	2.095e-13	78.0	COG2706@1|root,COG3386@1|root,COG2706@2|Bacteria,COG3386@2|Bacteria,4NK33@976|Bacteroidetes,1I2XS@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
WH2_k127_3709885_0	929556.Solca_0403	3.781e-70	251.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,4NF25@976|Bacteroidetes,1INUG@117747|Sphingobacteriia	976|Bacteroidetes	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
WH2_k127_3736011_0	1408433.JHXV01000033_gene1154	3.759e-106	367.0	28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,1I791@117743|Flavobacteriia,2PA5S@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3736011_2	762903.Pedsa_2033	6.577e-59	211.0	COG0344@1|root,COG0344@2|Bacteria,4NMU3@976|Bacteroidetes,1IPFE@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WH2_k127_3736011_1	1408433.JHXV01000033_gene1155	6.249e-94	340.0	COG0419@1|root,COG1196@1|root,COG3391@1|root,COG0419@2|Bacteria,COG1196@2|Bacteria,COG3391@2|Bacteria,4PP0U@976|Bacteroidetes,1ICPT@117743|Flavobacteriia,2PBJT@246874|Cryomorphaceae	976|Bacteroidetes	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_374779_0	1313421.JHBV01000015_gene5797	5.325e-38	161.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
WH2_k127_3757275_0	471854.Dfer_0995	0.0	1386.0	COG1538@1|root,COG3696@1|root,COG1538@2|Bacteria,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,47JC4@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
WH2_k127_3760511_0	1121895.Q765_17125	3.217e-72	247.0	COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,1HXXU@117743|Flavobacteriia,2NS8P@237|Flavobacterium	976|Bacteroidetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10,4.1.1.23	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
WH2_k127_3760511_3	929562.Emtol_0347	1.507e-31	133.0	COG0494@1|root,COG0494@2|Bacteria,4PKI3@976|Bacteroidetes,47Y1R@768503|Cytophagia	976|Bacteroidetes	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WH2_k127_3760511_4	1168289.AJKI01000011_gene605	2.99e-06	61.0	COG0526@1|root,COG0526@2|Bacteria,4NNSW@976|Bacteroidetes,2FXHS@200643|Bacteroidia,3XJPK@558415|Marinilabiliaceae	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_8
WH2_k127_3760511_2	1122176.KB903609_gene5132	1.289e-45	170.0	COG0669@1|root,COG0669@2|Bacteria,4NM84@976|Bacteroidetes,1ISUA@117747|Sphingobacteriia	976|Bacteroidetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WH2_k127_3760511_1	1127696.HMPREF9134_00769	1.936e-46	180.0	COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,2FSR0@200643|Bacteroidia,22XZ4@171551|Porphyromonadaceae	976|Bacteroidetes	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
WH2_k127_3762584_0	374847.Kcr_0638	1.332e-40	168.0	arCOG02559@1|root,arCOG02559@2157|Archaea	2157|Archaea	P	by modhmm	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
WH2_k127_3762584_3	1121895.Q765_18135	1.294e-16	85.0	COG3668@1|root,COG3668@2|Bacteria,4NX3F@976|Bacteroidetes	976|Bacteroidetes	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
WH2_k127_3762584_1	926559.JoomaDRAFT_3357	4.68e-22	97.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HY0V@117743|Flavobacteriia	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	accD5	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
WH2_k127_3762584_2	1121895.Q765_18135	9.354e-20	94.0	COG3668@1|root,COG3668@2|Bacteria,4NX3F@976|Bacteroidetes	976|Bacteroidetes	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
WH2_k127_3762584_4	1492737.FEM08_12290	3.196e-07	57.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HY0V@117743|Flavobacteriia,2NU4U@237|Flavobacterium	976|Bacteroidetes	I	Methylcrotonoyl-CoA carboxylase	accD5	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
WH2_k127_3762584_5	880072.Desac_2173	6.938e-07	56.0	COG1943@1|root,COG1943@2|Bacteria,1RIWM@1224|Proteobacteria,42SBY@68525|delta/epsilon subdivisions,2WPSK@28221|Deltaproteobacteria,2MS0M@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WH2_k127_3768906_2	880073.Calab_1716	6.093e-08	64.0	COG0737@1|root,COG2866@1|root,COG4412@1|root,COG0737@2|Bacteria,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	cpt	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14,Peptidase_M6,SBP_bac_8,SLH
WH2_k127_3768906_1	313594.PI23P_09560	1.113e-46	188.0	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,1HXIU@117743|Flavobacteriia,3VUZY@52959|Polaribacter	976|Bacteroidetes	S	Domain of unknown function (DUF4290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
WH2_k127_3768906_0	926562.Oweho_3050	6.405e-201	632.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,1HWNU@117743|Flavobacteriia,2PAEM@246874|Cryomorphaceae	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
WH2_k127_3775142_0	1408433.JHXV01000010_gene583	6.512e-36	153.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	2.1.1.72,3.1.4.46,3.2.1.1	ko:K00571,ko:K01126,ko:K01176	ko00500,ko00564,ko01100,ko04973,map00500,map00564,map01100,map04973	-	R01030,R01470,R02108,R02112,R11262	RC00017,RC00425	ko00000,ko00001,ko01000,ko02048	-	GH13	-	CHU_C,PKD
WH2_k127_3775142_1	906888.JCM19314_87	2.455e-07	57.0	COG4935@1|root,COG4935@2|Bacteria,4P0CG@976|Bacteroidetes,1I7QI@117743|Flavobacteriia,3HJAI@363408|Nonlabens	976|Bacteroidetes	O	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CUB,PKD,P_proprotein
WH2_k127_3791607_0	1122176.KB903550_gene4281	1.32e-233	764.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1J0XD@117747|Sphingobacteriia	976|Bacteroidetes	D	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
WH2_k127_3792539_0	1121904.ARBP01000016_gene5289	6.242e-165	532.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,47M2N@768503|Cytophagia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
WH2_k127_3792539_2	1122621.ATZA01000054_gene60	5.174e-26	115.0	COG2332@1|root,COG2332@2|Bacteria,4NN85@976|Bacteroidetes,1IT63@117747|Sphingobacteriia	976|Bacteroidetes	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
WH2_k127_3792539_3	1121957.ATVL01000008_gene4697	1.566e-05	52.0	2BZQ6@1|root,339SI@2|Bacteria,4NXJG@976|Bacteroidetes,47SN2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3792539_1	926562.Oweho_0195	3.797e-53	189.0	COG0755@1|root,COG0755@2|Bacteria,4NFUS@976|Bacteroidetes	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
WH2_k127_3794829_0	755732.Fluta_2012	1.043e-269	866.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1IG7B@117743|Flavobacteriia,2PBE8@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
WH2_k127_3794829_1	1453500.AT05_00675	6.69e-151	484.0	COG2159@1|root,COG2159@2|Bacteria,4NIGJ@976|Bacteroidetes,1HZPW@117743|Flavobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
WH2_k127_3794829_2	755732.Fluta_2018	4.443e-83	278.0	COG1917@1|root,COG1917@2|Bacteria,4PKJ0@976|Bacteroidetes,1IJAI@117743|Flavobacteriia,2PAU2@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
WH2_k127_3794829_4	1111730.ATTM01000013_gene2470	0.0005698	51.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CUB,Cleaved_Adhesin,MAM,fn3
WH2_k127_3794829_3	1121957.ATVL01000006_gene2766	3.862e-21	106.0	COG3291@1|root,COG3291@2|Bacteria,4NJHV@976|Bacteroidetes,47R0V@768503|Cytophagia	976|Bacteroidetes	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
WH2_k127_3795867_0	1144275.COCOR_02593	1.096e-186	616.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WN7A@28221|Deltaproteobacteria,2YTZA@29|Myxococcales	28221|Deltaproteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	ko:K16416	ko01052,map01052	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
WH2_k127_3844117_1	485918.Cpin_1652	1.534e-171	548.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1INWV@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
WH2_k127_3844117_0	1341155.FSS13T_16120	7.636e-235	751.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1HZCT@117743|Flavobacteriia,2NTX8@237|Flavobacterium	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
WH2_k127_3844117_2	547042.BACCOPRO_02509	4.047e-14	73.0	COG0529@1|root,COG0529@2|Bacteria,4NGCU@976|Bacteroidetes,2FMA4@200643|Bacteroidia,4ANMW@815|Bacteroidaceae	976|Bacteroidetes	F	Catalyzes the synthesis of activated sulfate	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
WH2_k127_3882763_1	1168034.FH5T_17700	1.68e-77	271.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,2FN98@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
WH2_k127_3882763_2	1223410.KN050846_gene1057	3.75e-06	57.0	COG2849@1|root,COG2849@2|Bacteria,4NP2Z@976|Bacteroidetes,1I22V@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
WH2_k127_3882763_0	929556.Solca_1206	1.741e-96	329.0	COG4953@1|root,COG4953@2|Bacteria,4NEG5@976|Bacteroidetes,1IP6N@117747|Sphingobacteriia	976|Bacteroidetes	M	Penicillin-binding Protein	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
WH2_k127_389208_1	755732.Fluta_0667	3.531e-06	57.0	28ZU6@1|root,2ZMIV@2|Bacteria,4P83G@976|Bacteroidetes,1IMR8@117743|Flavobacteriia,2PBNF@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_389208_0	1408813.AYMG01000023_gene2183	2.021e-163	541.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1IPIC@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WH2_k127_389208_2	1200792.AKYF01000018_gene5821	0.0009151	50.0	COG0726@1|root,COG0726@2|Bacteria,1TQYJ@1239|Firmicutes,4HE94@91061|Bacilli,26X61@186822|Paenibacillaceae	91061|Bacilli	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
WH2_k127_3896135_0	742767.HMPREF9456_03246	8.913e-12	75.0	COG4695@1|root,COG4695@2|Bacteria,4NW2N@976|Bacteroidetes,2FQR7@200643|Bacteroidia	976|Bacteroidetes	S	Phage portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
WH2_k127_3918542_0	1279009.ADICEAN_01577	4.989e-113	370.0	COG2141@1|root,COG2141@2|Bacteria,4NHGI@976|Bacteroidetes,47MJ4@768503|Cytophagia	976|Bacteroidetes	C	Luciferase-like monooxygenase	yhbW	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
WH2_k127_3962179_1	760192.Halhy_5043	1.661e-122	420.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1IPGC@117747|Sphingobacteriia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
WH2_k127_3962179_6	1408433.JHXV01000009_gene1220	2.939e-13	82.0	2AAU0@1|root,33Z6J@2|Bacteria,4P4NV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_3962179_0	378806.STAUR_2723	4.872e-196	629.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2X1X6@28221|Deltaproteobacteria,2YWKW@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.32,1.2.1.85	ko:K10217	ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220	M00038,M00569	R02762,R03889,R05353	RC00218,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WH2_k127_3962179_3	1185876.BN8_05716	1.381e-79	282.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,47MII@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	rprX3	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
WH2_k127_3962179_2	1121129.KB903371_gene166	7.293e-84	286.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia,22WBV@171551|Porphyromonadaceae	976|Bacteroidetes	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WH2_k127_3962179_4	1385517.N800_01540	1.175e-78	273.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,1S2WT@1236|Gammaproteobacteria,1XCC7@135614|Xanthomonadales	135614|Xanthomonadales	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH2_k127_3962179_7	1122179.KB890416_gene2670	0.0005308	53.0	COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	CHU_C,Haemagg_act,HemolysinCabind,PKD,SprB
WH2_k127_3962179_5	391587.KAOT1_12767	4.739e-23	108.0	COG1345@1|root,COG3291@1|root,COG1345@2|Bacteria,COG3291@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia	976|Bacteroidetes	N	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	CUB,LTD,fn3
WH2_k127_40339_1	385682.AFSL01000035_gene2905	4.11e-86	287.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,2FNVQ@200643|Bacteroidia,3XJ1K@558415|Marinilabiliaceae	976|Bacteroidetes	K	Sigma-70 region 3	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WH2_k127_40339_0	1122226.AUHX01000001_gene637	4.116e-176	565.0	COG0057@1|root,COG0057@2|Bacteria,4NG5C@976|Bacteroidetes,1HXX7@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA2	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
WH2_k127_40339_2	926562.Oweho_2612	1.66e-05	49.0	COG3291@1|root,COG3291@2|Bacteria,4NI4A@976|Bacteroidetes,1I0P7@117743|Flavobacteriia,2PBKJ@246874|Cryomorphaceae	976|Bacteroidetes	O	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Cleaved_Adhesin,MAM,PKD,fn3
WH2_k127_4050244_2	240015.ACP_0438	2.018e-55	201.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WH2_k127_4050244_0	1237149.C900_03832	2.437e-104	347.0	COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,47K33@768503|Cytophagia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
WH2_k127_4050244_1	1227739.Hsw_1926	1.778e-86	304.0	COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,47NIJ@768503|Cytophagia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
WH2_k127_4050244_3	391603.FBALC1_06778	1.049e-36	141.0	COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,1HWJW@117743|Flavobacteriia	976|Bacteroidetes	Q	COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
WH2_k127_4063832_0	1229276.DI53_0576	3.305e-134	440.0	COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,1INRF@117747|Sphingobacteriia	976|Bacteroidetes	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WH2_k127_4063832_2	1121931.AUHG01000018_gene1380	6.378e-63	229.0	COG3000@1|root,COG3000@2|Bacteria,4NMV7@976|Bacteroidetes,1I0S1@117743|Flavobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
WH2_k127_4063832_1	215803.DB30_5176	2.812e-63	218.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42UDS@68525|delta/epsilon subdivisions,2WPGE@28221|Deltaproteobacteria,2YV4M@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
WH2_k127_4077992_2	755732.Fluta_0703	1.138e-26	110.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4077992_0	1408433.JHXV01000020_gene3546	3.701e-96	327.0	COG2067@1|root,COG2067@2|Bacteria,4NWE8@976|Bacteroidetes,1I8GR@117743|Flavobacteriia,2PAP2@246874|Cryomorphaceae	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
WH2_k127_4077992_1	1450525.JATV01000003_gene1763	1.443e-56	201.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,1I18I@117743|Flavobacteriia,2NS6N@237|Flavobacterium	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
WH2_k127_4077992_3	742725.HMPREF9450_02184	3.182e-09	58.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,2FSRY@200643|Bacteroidia,22UGW@171550|Rikenellaceae	976|Bacteroidetes	FG	HIT domain	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
WH2_k127_4078771_0	926562.Oweho_0901	3.624e-110	367.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1HXSP@117743|Flavobacteriia,2PA4G@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WH2_k127_4078771_2	1408433.JHXV01000036_gene268	4.205e-33	143.0	2FG80@1|root,3484C@2|Bacteria,4P5E2@976|Bacteroidetes,1IAKI@117743|Flavobacteriia,2PB7R@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4078771_1	755732.Fluta_0259	2.392e-108	362.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,4NFIA@976|Bacteroidetes,1HXE1@117743|Flavobacteriia,2PAGQ@246874|Cryomorphaceae	976|Bacteroidetes	M	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
WH2_k127_4087451_0	743722.Sph21_2462	1.41e-268	837.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1IPEY@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WH2_k127_4087451_1	1408433.JHXV01000033_gene1145	2.658e-43	163.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia,2PAZS@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
WH2_k127_4087451_2	886377.Murru_2102	3.827e-09	60.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1HY78@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WH2_k127_40881_1	1538644.KO02_04650	1.487e-50	191.0	COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes,1IPC8@117747|Sphingobacteriia	976|Bacteroidetes	S	ribonuclease BN	yfkH	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
WH2_k127_40881_0	929556.Solca_2455	2.398e-97	328.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,1INNF@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
WH2_k127_40881_3	1358423.N180_20690	3.315e-15	85.0	2E4AG@1|root,33IJ2@2|Bacteria,4P9RI@976|Bacteroidetes,1IUJQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4783
WH2_k127_40881_2	243231.GSU3208	3.979e-26	117.0	COG1576@1|root,COG1576@2|Bacteria,1N7WB@1224|Proteobacteria,42V41@68525|delta/epsilon subdivisions,2X6IT@28221|Deltaproteobacteria,43UX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
WH2_k127_4109983_2	1392490.JHZX01000001_gene1425	1.138e-16	85.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1HYW1@117743|Flavobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WH2_k127_4109983_1	1223410.KN050846_gene1576	1.652e-61	227.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1HXW9@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
WH2_k127_4109983_0	1453500.AT05_05730	1.335e-186	600.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WH2_k127_4117077_0	1392489.JPOL01000002_gene796	2.015e-47	173.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,1HXFE@117743|Flavobacteriia,2XIDH@283735|Leeuwenhoekiella	976|Bacteroidetes	O	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
WH2_k127_4117077_2	755732.Fluta_0327	2.486e-20	101.0	2D45Q@1|root,32TGB@2|Bacteria,4NTFZ@976|Bacteroidetes,1IBQ1@117743|Flavobacteriia,2PBMI@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4117077_1	1237149.C900_03983	1.187e-21	99.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,47JYX@768503|Cytophagia	976|Bacteroidetes	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
WH2_k127_4122426_1	1347342.BN863_23390	2.742e-23	102.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HWKC@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
WH2_k127_4122426_2	1123037.AUDE01000019_gene3226	2.819e-20	108.0	COG1361@1|root,COG1361@2|Bacteria,4NMB8@976|Bacteroidetes,1I0EW@117743|Flavobacteriia	976|Bacteroidetes	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG
WH2_k127_4122426_0	313606.M23134_02237	6.716e-194	645.0	COG3209@1|root,COG3291@1|root,COG3386@1|root,COG4932@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,4NJ9V@976|Bacteroidetes,47N8F@768503|Cytophagia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
WH2_k127_413795_0	926562.Oweho_3003	1.96e-116	391.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1HXF3@117743|Flavobacteriia,2PABH@246874|Cryomorphaceae	976|Bacteroidetes	S	Transporter associated domain	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
WH2_k127_413795_1	755732.Fluta_0183	1.436e-30	124.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I27K@117743|Flavobacteriia,2PB1R@246874|Cryomorphaceae	976|Bacteroidetes	L	TIGRFAM single stranded DNA-binding protein (ssb)	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WH2_k127_4149945_0	1048983.EL17_01565	2.72e-125	418.0	COG2217@1|root,COG2217@2|Bacteria,4NEI1@976|Bacteroidetes,47N4X@768503|Cytophagia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
WH2_k127_417059_2	755732.Fluta_2063	1.837e-72	246.0	COG0677@1|root,COG0677@2|Bacteria,4NDTW@976|Bacteroidetes,1HWYT@117743|Flavobacteriia,2PA8J@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM UDP-glucose GDP-mannose dehydrogenase family, NAD binding domain	wbpO	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WH2_k127_417059_0	1124780.ANNU01000036_gene70	2.624e-161	514.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,47ME7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WH2_k127_417059_1	999419.HMPREF1077_02285	2.222e-93	313.0	COG0110@1|root,COG0110@2|Bacteria,4NENC@976|Bacteroidetes,2FP5Y@200643|Bacteroidia,22WU1@171551|Porphyromonadaceae	976|Bacteroidetes	S	Bacterial transferase hexapeptide repeat	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
WH2_k127_417059_3	926549.KI421517_gene3983	3.135e-65	232.0	COG0715@1|root,COG0715@2|Bacteria,4NETN@976|Bacteroidetes,47JG1@768503|Cytophagia	976|Bacteroidetes	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
WH2_k127_4182936_1	471854.Dfer_5791	1.207e-46	179.0	298PT@1|root,2ZVU7@2|Bacteria,4NPTP@976|Bacteroidetes,47RY6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4182936_2	1469557.JSWF01000014_gene2450	2.984e-25	111.0	COG5553@1|root,COG5553@2|Bacteria,4NSCH@976|Bacteroidetes,1I45S@117743|Flavobacteriia	976|Bacteroidetes	S	Cysteine dioxygenase type I	-	-	1.13.11.20	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	-	R00893	RC00404	ko00000,ko00001,ko01000	-	-	-	CDO_I
WH2_k127_4182936_0	471854.Dfer_5317	7.822e-95	323.0	COG0642@1|root,COG2205@2|Bacteria,4NG0Y@976|Bacteroidetes,47JUV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
WH2_k127_4199861_0	1408433.JHXV01000019_gene1953	5.413e-36	155.0	COG2885@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,4P343@976|Bacteroidetes	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
WH2_k127_4202079_0	85643.Tmz1t_2598	3.025e-270	836.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,2VHXU@28216|Betaproteobacteria,2KUBH@206389|Rhodocyclales	206389|Rhodocyclales	C	to the heme-copper respiratory oxidase family	norB	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
WH2_k127_4202079_1	85643.Tmz1t_2597	3.307e-91	300.0	COG2010@1|root,COG2010@2|Bacteria,1RDSI@1224|Proteobacteria,2VQ50@28216|Betaproteobacteria,2KW5Y@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c	norC	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrom_C
WH2_k127_4210612_0	388413.ALPR1_13679	1.691e-62	221.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,47NCP@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
WH2_k127_4217156_2	1121373.KB903627_gene2914	7.227e-94	312.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,47MI0@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
WH2_k127_4217156_3	1408433.JHXV01000006_gene2725	2.567e-78	273.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1HXT1@117743|Flavobacteriia,2PAQC@246874|Cryomorphaceae	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
WH2_k127_4217156_1	518766.Rmar_1597	8.011e-106	358.0	COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,1FIM9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WH2_k127_4217156_5	342113.DM82_4539	1.102e-44	171.0	COG0702@1|root,COG0702@2|Bacteria,1MZG7@1224|Proteobacteria,2VRAU@28216|Betaproteobacteria,1K8ZB@119060|Burkholderiaceae	28216|Betaproteobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
WH2_k127_4217156_15	1237149.C900_03337	1.448e-20	101.0	295IV@1|root,2ZSWC@2|Bacteria,4NVMA@976|Bacteroidetes,47W1I@768503|Cytophagia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4217156_9	643867.Ftrac_3100	2.862e-31	128.0	COG1846@1|root,COG1846@2|Bacteria,4PKFS@976|Bacteroidetes,47V9T@768503|Cytophagia	976|Bacteroidetes	K	Winged helix DNA-binding domain	marR	-	-	-	-	-	-	-	-	-	-	-	HTH_34
WH2_k127_4217156_12	1185876.BN8_01289	1.466e-23	109.0	COG5395@1|root,COG5395@2|Bacteria,4NTQ5@976|Bacteroidetes,47V8X@768503|Cytophagia	976|Bacteroidetes	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
WH2_k127_4217156_4	926562.Oweho_3340	9.815e-62	229.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme,Sulfatase
WH2_k127_4217156_17	7739.XP_002608277.1	7.347e-07	63.0	KOG1215@1|root,KOG1215@2759|Eukaryota	2759|Eukaryota	G	endocytosis	CD320	GO:0002376,GO:0002682,GO:0002684,GO:0002694,GO:0002696,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005783,GO:0005886,GO:0005887,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0006810,GO:0006855,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0009235,GO:0009987,GO:0010008,GO:0012505,GO:0015238,GO:0015399,GO:0015405,GO:0015420,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0019222,GO:0019842,GO:0022804,GO:0022857,GO:0030656,GO:0030888,GO:0030890,GO:0031090,GO:0031224,GO:0031226,GO:0031294,GO:0031296,GO:0031410,GO:0031419,GO:0031982,GO:0032944,GO:0032946,GO:0033013,GO:0035461,GO:0036094,GO:0042127,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0046483,GO:0046872,GO:0046906,GO:0048037,GO:0048518,GO:0048522,GO:0050670,GO:0050671,GO:0050789,GO:0050794,GO:0050864,GO:0050865,GO:0050867,GO:0050871,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051184,GO:0051186,GO:0051234,GO:0051249,GO:0051251,GO:0055085,GO:0062012,GO:0065007,GO:0070663,GO:0070665,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0090482,GO:0097159,GO:0097708,GO:0098588,GO:0098805,GO:1901360,GO:1901363,GO:1901564	3.4.15.1,3.4.21.7	ko:K01283,ko:K01315,ko:K02599,ko:K06734,ko:K20050	ko01522,ko04080,ko04320,ko04330,ko04610,ko04614,ko04658,ko04919,ko04924,ko05020,ko05142,ko05150,ko05164,ko05165,ko05200,ko05206,ko05224,ko05410,map01522,map04080,map04320,map04330,map04610,map04614,map04658,map04919,map04924,map05020,map05142,map05150,map05164,map05165,map05200,map05206,map05224,map05410	M00682	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko04090,ko04131,ko04147,ko04516	-	-	-	CUB,Ldl_recept_a
WH2_k127_4217156_8	1122179.KB890449_gene132	1.584e-37	164.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1IPFX@117747|Sphingobacteriia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
WH2_k127_4217156_16	485918.Cpin_1738	1.475e-13	85.0	COG3291@1|root,COG3291@2|Bacteria,4NJQN@976|Bacteroidetes,1IXWG@117747|Sphingobacteriia	976|Bacteroidetes	M	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,IgGFc_binding,PKD,SprB,fn3
WH2_k127_4217156_6	925409.KI911562_gene1621	2.681e-42	174.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	OprB,PorP_SprF,SLH,Toluene_X
WH2_k127_4217156_7	491205.JARQ01000004_gene2495	1.392e-39	154.0	2CCNY@1|root,2Z877@2|Bacteria,4NR3D@976|Bacteroidetes,1I3KA@117743|Flavobacteriia	976|Bacteroidetes	E	CpeT/CpcT family (DUF1001)	-	-	-	-	-	-	-	-	-	-	-	-	CpeT
WH2_k127_4217156_0	643867.Ftrac_0021	4.558e-280	874.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,47KGW@768503|Cytophagia	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
WH2_k127_4245811_0	1121957.ATVL01000008_gene4616	3.827e-48	179.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,47KCK@768503|Cytophagia	976|Bacteroidetes	E	Aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WH2_k127_4256256_1	867900.Celly_1162	3.639e-18	95.0	COG0782@1|root,COG0782@2|Bacteria,4NW1R@976|Bacteroidetes,1I31U@117743|Flavobacteriia,1F9F0@104264|Cellulophaga	976|Bacteroidetes	J	PFAM Transcription elongation factor, GreA GreB, C-term	-	-	-	ko:K06140	-	-	-	-	ko00000,ko03000	-	-	-	GreA_GreB
WH2_k127_4256256_0	1121007.AUML01000014_gene2848	2.277e-110	368.0	COG1282@1|root,COG1282@2|Bacteria,4NHGZ@976|Bacteroidetes,1I02T@117743|Flavobacteriia	976|Bacteroidetes	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
WH2_k127_4267346_3	886379.AEWI01000023_gene66	3.613e-05	50.0	2E8XD@1|root,3337D@2|Bacteria,4NW3N@976|Bacteroidetes,2FVQT@200643|Bacteroidia,3XKVX@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4267346_2	1227739.Hsw_0521	1.763e-10	67.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,47PWE@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH2_k127_4267346_1	1392490.JHZX01000001_gene1821	7.985e-22	107.0	COG1595@1|root,COG1595@2|Bacteria,4NRAJ@976|Bacteroidetes,1IJ13@117743|Flavobacteriia	976|Bacteroidetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
WH2_k127_4267346_0	1189612.A33Q_2651	2.65e-25	116.0	COG0457@1|root,COG0457@2|Bacteria,4NNXW@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
WH2_k127_4272739_3	743722.Sph21_3880	1.184e-43	161.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1IQF4@117747|Sphingobacteriia	976|Bacteroidetes	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
WH2_k127_4272739_6	1270196.JCKI01000006_gene2655	9.095e-17	84.0	COG2026@1|root,COG2026@2|Bacteria,4PBVX@976|Bacteroidetes,1J03J@117747|Sphingobacteriia	976|Bacteroidetes	DJ	Addiction module toxin, RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4272739_7	313606.M23134_07118	5.107e-09	66.0	COG1280@1|root,COG1280@2|Bacteria,4NQHY@976|Bacteroidetes	976|Bacteroidetes	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
WH2_k127_4272739_8	391625.PPSIR1_33084	2.139e-05	53.0	COG1073@1|root,COG1073@2|Bacteria,1PBV5@1224|Proteobacteria,433TK@68525|delta/epsilon subdivisions,2X3EJ@28221|Deltaproteobacteria,2YVQG@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised protein family (UPF0227)	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
WH2_k127_4272739_0	1123037.AUDE01000019_gene3324	4.394e-133	442.0	28KN2@1|root,2ZA6D@2|Bacteria,4NG7P@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4272739_1	1399115.U719_07560	1.722e-120	402.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,3WG3C@539002|Bacillales incertae sedis	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WH2_k127_4272739_2	1121448.DGI_0438	8.893e-83	288.0	COG1215@1|root,COG1215@2|Bacteria,1R988@1224|Proteobacteria,42QGX@68525|delta/epsilon subdivisions,2WJPU@28221|Deltaproteobacteria,2M8JN@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH2_k127_4272739_5	999541.bgla_1g07250	2.748e-23	113.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,1K0Y6@119060|Burkholderiaceae	28216|Betaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
WH2_k127_4272739_4	313606.M23134_02426	1.099e-38	148.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,47MIN@768503|Cytophagia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
WH2_k127_4282409_3	1048983.EL17_01605	2.599e-10	63.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,47KT1@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase accessory protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
WH2_k127_4282409_2	1279009.ADICEAN_00455	5.261e-13	77.0	COG5456@1|root,COG5456@2|Bacteria,4NUZC@976|Bacteroidetes,47YSU@768503|Cytophagia	976|Bacteroidetes	P	PFAM FixH	ccoH	-	-	-	-	-	-	-	-	-	-	-	FixH
WH2_k127_4282409_1	1168034.FH5T_09735	2.409e-37	151.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes	976|Bacteroidetes	S	cytochrome c biogenesis protein	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
WH2_k127_4282409_0	1358423.N180_02310	1.302e-55	201.0	COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,1ISJ5@117747|Sphingobacteriia	976|Bacteroidetes	I	Beta-carotene hydroxylase	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
WH2_k127_4312447_1	1453500.AT05_11180	4.124e-96	328.0	COG0477@1|root,COG2814@2|Bacteria,4NFM7@976|Bacteroidetes,1HYPP@117743|Flavobacteriia	976|Bacteroidetes	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WH2_k127_4312447_0	755732.Fluta_3899	2.808e-150	482.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1HX04@117743|Flavobacteriia,2PA4I@246874|Cryomorphaceae	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
WH2_k127_4320141_4	485918.Cpin_1092	1.424e-60	219.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,1IQA3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4320141_2	1408433.JHXV01000001_gene701	6.521e-78	276.0	COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes,1HXXM@117743|Flavobacteriia,2PAS3@246874|Cryomorphaceae	976|Bacteroidetes	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
WH2_k127_4320141_7	1408433.JHXV01000001_gene700	7.085e-31	137.0	COG1845@1|root,COG1845@2|Bacteria,4NFA7@976|Bacteroidetes,1I1D8@117743|Flavobacteriia,2PB9Z@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Cytochrome c oxidase, subunit III	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
WH2_k127_4320141_1	755732.Fluta_1919	1.089e-99	333.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,1HWXP@117743|Flavobacteriia,2PAN3@246874|Cryomorphaceae	976|Bacteroidetes	C	Heme copper-type cytochrome quinol oxidase subunit 3	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
WH2_k127_4320141_6	755732.Fluta_1918	5.356e-41	154.0	COG5605@1|root,COG5605@2|Bacteria,4P9DD@976|Bacteroidetes,1IC4B@117743|Flavobacteriia,2PB81@246874|Cryomorphaceae	976|Bacteroidetes	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
WH2_k127_4320141_5	1408433.JHXV01000001_gene696	4.59e-43	170.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1I3NA@117743|Flavobacteriia,2PB1N@246874|Cryomorphaceae	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
WH2_k127_4320141_3	929713.NIASO_13350	2.282e-61	216.0	COG2322@1|root,COG2322@2|Bacteria,4NM5N@976|Bacteroidetes,1ITGM@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
WH2_k127_4320141_8	555500.I215_00125	4.439e-05	54.0	2E3I4@1|root,32YGK@2|Bacteria,4NUQ9@976|Bacteroidetes,1I53J@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4320141_0	1121022.ABENE_17910	5.499e-101	339.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TUXY@28211|Alphaproteobacteria,2KFZ6@204458|Caulobacterales	204458|Caulobacterales	EU	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WH2_k127_432038_4	153721.MYP_1137	1.536e-22	102.0	COG3291@1|root,COG4935@1|root,COG5644@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,COG5644@2|Bacteria,4NJRF@976|Bacteroidetes,47PMY@768503|Cytophagia	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
WH2_k127_432038_2	927658.AJUM01000022_gene1004	3.168e-80	279.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,2FTFG@200643|Bacteroidia,3XJ5W@558415|Marinilabiliaceae	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
WH2_k127_432038_1	504472.Slin_1311	5.478e-103	362.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47K1N@768503|Cytophagia	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
WH2_k127_432038_5	929703.KE386491_gene193	4.125e-21	100.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,47RW1@768503|Cytophagia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	PI-PLC-C1,Rhodanese
WH2_k127_432038_3	925409.KI911562_gene183	1.565e-56	204.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1IRUN@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	pgdA_1	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
WH2_k127_432038_0	1408473.JHXO01000010_gene3689	3.22e-170	556.0	COG0038@1|root,COG0038@2|Bacteria,4NZYS@976|Bacteroidetes,2G0DB@200643|Bacteroidia	976|Bacteroidetes	P	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
WH2_k127_4331584_1	1189612.A33Q_0506	3.041e-78	268.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,47JXF@768503|Cytophagia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
WH2_k127_4331584_0	485918.Cpin_6977	1.034e-95	330.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1IPWG@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
WH2_k127_4331584_2	477974.Daud_1438	6.91e-26	112.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,260PC@186807|Peptococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WH2_k127_4334405_1	649831.L083_4290	1.698e-08	66.0	COG1572@1|root,COG1572@2|Bacteria,2GKNI@201174|Actinobacteria,4DJGB@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5122,HemolysinCabind
WH2_k127_4334405_0	1121481.AUAS01000001_gene4595	1.374e-29	120.0	COG2026@1|root,COG2026@2|Bacteria,4NW0W@976|Bacteroidetes,47SBC@768503|Cytophagia	976|Bacteroidetes	DJ	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	RelE
WH2_k127_4344999_1	1123248.KB893359_gene2055	1.309e-93	320.0	COG0682@1|root,COG0682@2|Bacteria,4NGSG@976|Bacteroidetes,1INRB@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT
WH2_k127_4344999_2	926549.KI421517_gene1121	8.058e-86	292.0	COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,47K2K@768503|Cytophagia	976|Bacteroidetes	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
WH2_k127_4344999_0	883096.HMPREF9699_00936	3.263e-134	440.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,1HY2R@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
WH2_k127_4348267_1	760192.Halhy_3950	6.06e-60	215.0	COG0204@1|root,COG0204@2|Bacteria,4NNG7@976|Bacteroidetes,1IYKW@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
WH2_k127_4348267_2	1279009.ADICEAN_01347	1.24e-33	136.0	2DZGZ@1|root,32VAD@2|Bacteria,4NSFP@976|Bacteroidetes,47RS7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_10
WH2_k127_4348267_0	1123234.AUKI01000005_gene122	2.355e-74	256.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiC	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
WH2_k127_4419591_2	313606.M23134_05103	1.231e-17	89.0	COG3137@1|root,COG3137@2|Bacteria,4NHQU@976|Bacteroidetes,47KAT@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
WH2_k127_4419591_0	1239962.C943_01255	1.953e-128	417.0	COG3781@1|root,COG3781@2|Bacteria,4NGJ0@976|Bacteroidetes,47KN8@768503|Cytophagia	976|Bacteroidetes	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
WH2_k127_4419591_1	1121380.JNIW01000081_gene129	1.381e-54	193.0	COG0693@1|root,COG0693@2|Bacteria	2|Bacteria	S	protein deglycation	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
WH2_k127_4430220_1	865938.Weevi_0421	2.046e-74	266.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,1HXKN@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
WH2_k127_4430220_0	1408813.AYMG01000008_gene4008	2.977e-100	346.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1IQ4H@117747|Sphingobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
WH2_k127_444519_1	926562.Oweho_3433	2.042e-23	104.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,1IG8B@117743|Flavobacteriia,2PBXI@246874|Cryomorphaceae	976|Bacteroidetes	P	PFAM Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WH2_k127_444519_0	1122621.ATZA01000010_gene160	3.819e-54	195.0	COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,1IRXR@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
WH2_k127_445943_0	1120968.AUBX01000014_gene2618	1.152e-90	310.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,47K9H@768503|Cytophagia	976|Bacteroidetes	L	DNA-directed DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
WH2_k127_445943_3	319225.Plut_2079	4.316e-37	159.0	COG4704@1|root,COG4704@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4189,Fib_succ_major
WH2_k127_445943_4	715226.ABI_30460	0.0005125	48.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TWG2@28211|Alphaproteobacteria,2KFSP@204458|Caulobacterales	204458|Caulobacterales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,EAL,HAMP,HATPase_c,HisKA,Hpt,Response_reg
WH2_k127_445943_1	313606.M23134_07734	7.869e-63	225.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,47NAQ@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH2_k127_445943_2	1408433.JHXV01000027_gene3728	2.867e-40	172.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
WH2_k127_4486915_0	1408433.JHXV01000020_gene3566	1.784e-48	186.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF285,Flg_new,LRR_5,Lipase_GDSL_2,SLH,fn3
WH2_k127_4486915_2	1408433.JHXV01000040_gene1535	1.773e-12	67.0	COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,1HWNW@117743|Flavobacteriia,2PAA5@246874|Cryomorphaceae	976|Bacteroidetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WH2_k127_4494154_0	313596.RB2501_04560	7.522e-176	559.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,1HXFK@117743|Flavobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
WH2_k127_4494154_2	1454007.JAUG01000007_gene2152	2.958e-48	181.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
WH2_k127_4494154_1	1408433.JHXV01000002_gene476	3.092e-96	322.0	COG1974@1|root,COG1974@2|Bacteria,4PKQ7@976|Bacteroidetes,1IJGW@117743|Flavobacteriia,2PAZ2@246874|Cryomorphaceae	976|Bacteroidetes	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
WH2_k127_4506088_0	755732.Fluta_1300	2.069e-150	486.0	COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,1HWNW@117743|Flavobacteriia,2PAA5@246874|Cryomorphaceae	976|Bacteroidetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WH2_k127_4506088_1	1353276.JADR01000003_gene2771	4.22e-124	405.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1HXG2@117743|Flavobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
WH2_k127_4535426_5	1250232.JQNJ01000001_gene3577	2.431e-30	129.0	2CCJ7@1|root,2ZA02@2|Bacteria,4NGH8@976|Bacteroidetes,1HXKM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4535426_9	290402.Cbei_2113	2.821e-08	61.0	2EP32@1|root,33GPV@2|Bacteria,1VQR5@1239|Firmicutes,24RRT@186801|Clostridia,36SIR@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF1883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1883
WH2_k127_4535426_2	1506583.JQJY01000002_gene1258	6.647e-58	211.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1HYE4@117743|Flavobacteriia,2NT1B@237|Flavobacterium	976|Bacteroidetes	T	Belongs to the universal stress protein A family	uspA	-	-	-	-	-	-	-	-	-	-	-	Usp
WH2_k127_4535426_6	385682.AFSL01000003_gene1912	2.955e-26	112.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,2G24U@200643|Bacteroidia,3XK3Q@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
WH2_k127_4535426_3	1121904.ARBP01000007_gene3099	2.339e-39	159.0	COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,47WA7@768503|Cytophagia	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4535426_0	391596.PBAL39_09991	4.775e-125	406.0	COG1028@1|root,COG1028@2|Bacteria,4NE45@976|Bacteroidetes,1IR0M@117747|Sphingobacteriia	976|Bacteroidetes	IQ	short-chain dehydrogenase	ykuF	-	-	ko:K13774	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short_C2
WH2_k127_4535426_8	1174528.JH992898_gene4701	7.861e-13	79.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2
WH2_k127_4535426_4	1408433.JHXV01000005_gene2331	4.971e-33	145.0	2A94Y@1|root,30Y99@2|Bacteria,4PC0Q@976|Bacteroidetes,1ICRR@117743|Flavobacteriia,2PBX3@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4535426_7	1189619.pgond44_00060	9.21e-25	111.0	2E9TR@1|root,333ZQ@2|Bacteria,4NVUY@976|Bacteroidetes,1IBIA@117743|Flavobacteriia,4C3NN@83612|Psychroflexus	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WH2_k127_4535426_1	1313301.AUGC01000007_gene559	1.349e-79	274.0	COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes	976|Bacteroidetes	H	magnesium chelatase	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Sigma54_activat
WH2_k127_45452_2	1122176.KB903602_gene5067	1.246e-08	60.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IXJP@117747|Sphingobacteriia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB,TIG
WH2_k127_45452_1	96561.Dole_0790	1.996e-30	136.0	COG3292@1|root,COG3292@2|Bacteria,1QU1S@1224|Proteobacteria,42WTY@68525|delta/epsilon subdivisions,2WSR0@28221|Deltaproteobacteria,2MNQR@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PKD,Peptidase_C13,Reg_prop
WH2_k127_45452_0	1089547.KB913013_gene4607	7.238e-40	167.0	COG4935@1|root,COG4935@2|Bacteria,4NWJG@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Lysyl_oxidase,P_proprotein
WH2_k127_45452_4	153721.MYP_563	0.0002687	53.0	COG2373@1|root,COG3055@1|root,COG3386@1|root,COG4099@1|root,COG4733@1|root,COG2373@2|Bacteria,COG3055@2|Bacteria,COG3386@2|Bacteria,COG4099@2|Bacteria,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PA14,fn3
WH2_k127_45452_3	1408813.AYMG01000014_gene1651	1.362e-06	61.0	COG1361@1|root,COG3291@1|root,COG4625@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG4625@2|Bacteria,4NDZC@976|Bacteroidetes,1IRJP@117747|Sphingobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CHU_C,DUF11,He_PIG,fn3
WH2_k127_4548130_0	1124780.ANNU01000006_gene2911	1.499e-53	192.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,47K4M@768503|Cytophagia	976|Bacteroidetes	S	PFAM MazG nucleotide pyrophosphohydrolase	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
WH2_k127_4548130_3	1353276.JADR01000002_gene1973	7.383e-32	144.0	COG3291@1|root,COG4412@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Cleaved_Adhesin,Peptidase_M30,fn3
WH2_k127_4548130_5	525373.HMPREF0766_11949	3.333e-17	96.0	COG2911@1|root,COG3209@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
WH2_k127_4548130_4	1122176.KB903531_gene3077	7.629e-24	118.0	COG3291@1|root,COG3291@2|Bacteria,4NICC@976|Bacteroidetes,1IXKI@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
WH2_k127_4548130_1	1121904.ARBP01000009_gene4379	5.569e-48	185.0	2DICZ@1|root,32UAY@2|Bacteria,4NU7D@976|Bacteroidetes,47SYM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4548130_2	929562.Emtol_3674	3.72e-38	146.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,47JTY@768503|Cytophagia	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
WH2_k127_4561357_1	1185876.BN8_00853	8.497e-12	76.0	COG2885@1|root,COG2885@2|Bacteria,4NMTI@976|Bacteroidetes,47PC5@768503|Cytophagia	976|Bacteroidetes	M	GLEYA domain	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PA14
WH2_k127_4561357_0	1434325.AZQN01000004_gene1645	1.357e-33	147.0	COG3292@1|root,COG3920@1|root,COG3292@2|Bacteria,COG3920@2|Bacteria,4NJ2Y@976|Bacteroidetes,47N0D@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,HisKA_2,Reg_prop,Response_reg,Y_Y_Y
WH2_k127_4566374_1	755732.Fluta_3635	1.503e-25	123.0	COG0457@1|root,COG0457@2|Bacteria,4P3PK@976|Bacteroidetes,1ICNQ@117743|Flavobacteriia,2PBCJ@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4566374_0	929713.NIASO_04760	2.737e-64	234.0	COG0665@1|root,COG0665@2|Bacteria,4NEEY@976|Bacteroidetes,1IPIG@117747|Sphingobacteriia	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
WH2_k127_4572006_1	1410608.JNKX01000042_gene1161	3.797e-33	138.0	COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes,2FP63@200643|Bacteroidia,4AN9T@815|Bacteroidaceae	976|Bacteroidetes	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
WH2_k127_4572006_0	1174528.JH992890_gene534	2.325e-61	227.0	COG2957@1|root,COG2957@2|Bacteria,1G1FA@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the agmatine deiminase family	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
WH2_k127_4573848_0	926562.Oweho_0750	7.81e-219	694.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1HXSG@117743|Flavobacteriia,2PA5D@246874|Cryomorphaceae	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WH2_k127_4573848_2	1197477.IA57_00455	0.0003976	51.0	2E7SQ@1|root,3327W@2|Bacteria,4NUWY@976|Bacteroidetes,1I5CR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4573848_1	714943.Mucpa_1515	3.278e-67	232.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1INT7@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
WH2_k127_4599660_0	118163.Ple7327_0036	1.149e-38	148.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1GQBE@1117|Cyanobacteria,3VIKN@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
WH2_k127_4599660_1	1392488.JHZY01000004_gene2539	1.472e-32	143.0	COG2911@1|root,COG3209@1|root,COG5184@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG5184@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
WH2_k127_4599660_2	700598.Niako_6317	1.316e-18	99.0	COG1044@1|root,COG1044@2|Bacteria,4NT1C@976|Bacteroidetes,1J18R@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4619512_2	1379698.RBG1_1C00001G0540	3.468e-05	56.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,SBBP
WH2_k127_4619512_0	616991.JPOO01000003_gene450	1.217e-78	271.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,1HWQK@117743|Flavobacteriia,23H09@178469|Arenibacter	976|Bacteroidetes	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
WH2_k127_4619512_1	1279009.ADICEAN_02139	2.099e-40	162.0	COG1520@1|root,COG1520@2|Bacteria,4PKMD@976|Bacteroidetes,47QM2@768503|Cytophagia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4668025_3	926549.KI421517_gene1957	4.216e-26	117.0	COG0713@1|root,COG0713@2|Bacteria,4NTBP@976|Bacteroidetes,47QG0@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
WH2_k127_4668025_2	485918.Cpin_7010	6.265e-43	163.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,1ISVB@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
WH2_k127_4668025_1	1123058.KB894240_gene2003	9.155e-74	252.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,1I2F9@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
WH2_k127_4668025_0	1121373.KB903623_gene2358	7.622e-90	299.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,47K9J@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
WH2_k127_4673798_0	929556.Solca_4100	6.87e-186	596.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1IPFU@117747|Sphingobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WH2_k127_4711841_0	1121875.KB907552_gene171	6.253e-91	316.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,1HYA7@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WH2_k127_4711841_1	1408473.JHXO01000011_gene3138	1.059e-29	134.0	28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,2FV47@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4711841_2	1121033.AUCF01000011_gene1733	2.869e-24	108.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,2TS96@28211|Alphaproteobacteria,2JP84@204441|Rhodospirillales	204441|Rhodospirillales	E	periplasmic protein kinase ArgK and related GTPases of G3E family	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
WH2_k127_4720196_1	344747.PM8797T_02314	8.696e-31	130.0	COG3055@1|root,COG3055@2|Bacteria,2IY7R@203682|Planctomycetes	203682|Planctomycetes	E	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
WH2_k127_4720196_2	511062.GU3_06725	1.912e-18	91.0	COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,1SCD4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Transglycosylase-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
WH2_k127_4720196_0	762903.Pedsa_1149	5.858e-94	314.0	COG0412@1|root,COG0412@2|Bacteria,4NKMA@976|Bacteroidetes,1IQ0X@117747|Sphingobacteriia	976|Bacteroidetes	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
WH2_k127_4725489_0	1121373.KB903621_gene1893	1.506e-45	185.0	COG1807@1|root,COG1807@2|Bacteria,4P3UD@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4733338_0	1185876.BN8_04425	2.024e-91	319.0	COG1278@1|root,COG1432@1|root,COG1278@2|Bacteria,COG1432@2|Bacteria,4NHGS@976|Bacteroidetes,47JDZ@768503|Cytophagia	976|Bacteroidetes	K	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	CSD,NYN
WH2_k127_4733338_1	1043493.BBLU01000011_gene279	4.627e-24	106.0	COG5002@1|root,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WH2_k127_4734065_0	755732.Fluta_2021	4.866e-59	223.0	COG3291@1|root,COG3291@2|Bacteria,4PFQY@976|Bacteroidetes,1ICPB@117743|Flavobacteriia,2PBH6@246874|Cryomorphaceae	976|Bacteroidetes	S	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta
WH2_k127_474065_0	1408433.JHXV01000019_gene1933	1.476e-103	344.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,1HWQA@117743|Flavobacteriia,2PAFB@246874|Cryomorphaceae	976|Bacteroidetes	I	Enoyl-CoA hydratase/isomerase	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
WH2_k127_474065_1	385682.AFSL01000053_gene460	7.291e-94	319.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,2FRVJ@200643|Bacteroidia,3XIZ5@558415|Marinilabiliaceae	976|Bacteroidetes	T	GHKL domain	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WH2_k127_4744867_1	929556.Solca_2268	9.582e-94	328.0	COG0758@1|root,COG1948@1|root,COG0758@2|Bacteria,COG1948@2|Bacteria,4NF7T@976|Bacteroidetes,1IPSK@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
WH2_k127_4744867_0	755732.Fluta_1488	9.108e-167	554.0	COG4206@1|root,COG4206@2|Bacteria,4NIJS@976|Bacteroidetes	976|Bacteroidetes	H	COG4206 Outer membrane cobalamin receptor protein	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WH2_k127_4744867_2	1089547.KB913013_gene626	9.648e-74	255.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,47M2Z@768503|Cytophagia	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
WH2_k127_4744867_3	1453500.AT05_10105	2.652e-30	124.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes,1HYQM@117743|Flavobacteriia	976|Bacteroidetes	D	sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
WH2_k127_477459_0	1250232.JQNJ01000001_gene3721	0.0	1107.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
WH2_k127_4786752_0	984262.SGRA_2537	9.775e-61	220.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes	976|Bacteroidetes	DZ	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
WH2_k127_4786752_2	983548.Krodi_0718	1.164e-48	188.0	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,1HZG3@117743|Flavobacteriia,37EC6@326319|Dokdonia	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
WH2_k127_4786752_3	1267211.KI669560_gene1570	2.573e-34	136.0	COG1051@1|root,COG1051@2|Bacteria,4NR5C@976|Bacteroidetes,1ISSM@117747|Sphingobacteriia	976|Bacteroidetes	F	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WH2_k127_4786752_1	1123277.KB893172_gene849	5.601e-50	195.0	COG3291@1|root,COG3509@1|root,COG4102@1|root,COG3291@2|Bacteria,COG3509@2|Bacteria,COG4102@2|Bacteria,4PKN1@976|Bacteroidetes,47N1I@768503|Cytophagia	976|Bacteroidetes	G	Cellulase N-terminal ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9
WH2_k127_4793946_1	448385.sce7429	3.967e-05	55.0	COG1520@1|root,COG1520@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
WH2_k127_4793946_0	1227272.HMPREF1556_00677	2.211e-53	196.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,2FNUW@200643|Bacteroidia,22VX2@171551|Porphyromonadaceae	976|Bacteroidetes	E	Belongs to the DapB family	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
WH2_k127_4811872_4	980584.AFPB01000142_gene1144	1.315e-14	78.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,1HWNH@117743|Flavobacteriia,4065V@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
WH2_k127_4811872_1	755732.Fluta_3569	4.845e-56	197.0	COG1143@1|root,COG1143@2|Bacteria,4PKCQ@976|Bacteroidetes,1IJ7N@117743|Flavobacteriia,2PAUC@246874|Cryomorphaceae	976|Bacteroidetes	C	4Fe-4S binding domain	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
WH2_k127_4811872_2	1168289.AJKI01000035_gene3569	4.166e-41	166.0	28P29@1|root,2ZBYD@2|Bacteria,4NMK6@976|Bacteroidetes,2FVVU@200643|Bacteroidia,3XJT8@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4811872_0	1453500.AT05_00910	5.464e-147	474.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,1HYNV@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
WH2_k127_4811872_3	1122226.AUHX01000001_gene754	6.155e-19	100.0	COG0111@1|root,COG0111@2|Bacteria,4NDVN@976|Bacteroidetes,1HWXS@117743|Flavobacteriia	976|Bacteroidetes	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WH2_k127_4813032_0	1506583.JQJY01000005_gene2178	1.322e-286	893.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HWXY@117743|Flavobacteriia,2NT1D@237|Flavobacterium	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
WH2_k127_4830779_0	700598.Niako_6184	9.032e-19	90.0	COG1403@1|root,COG1403@2|Bacteria,4NT0M@976|Bacteroidetes,1IY6Z@117747|Sphingobacteriia	976|Bacteroidetes	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4832639_2	228405.HNE_3279	1.951e-09	62.0	COG3801@1|root,COG3801@2|Bacteria,1REJV@1224|Proteobacteria,2U8BB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
WH2_k127_4832639_0	1408433.JHXV01000006_gene2765	2.374e-41	172.0	COG2272@1|root,COG2272@2|Bacteria,4PI06@976|Bacteroidetes,1IG13@117743|Flavobacteriia,2PB7F@246874|Cryomorphaceae	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	COesterase
WH2_k127_4832639_1	558152.IQ37_18580	1.046e-15	90.0	COG4886@1|root,COG4886@2|Bacteria,4PB1B@976|Bacteroidetes,1HZE3@117743|Flavobacteriia,3ZQME@59732|Chryseobacterium	976|Bacteroidetes	S	Secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4847012_1	1089547.KB913013_gene2526	1.613e-05	53.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NGJJ@976|Bacteroidetes,47KNC@768503|Cytophagia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4847012_0	1122176.KB903576_gene5010	4.206e-53	201.0	COG2133@1|root,COG4886@1|root,COG2133@2|Bacteria,COG4886@2|Bacteria,4NF0B@976|Bacteroidetes,1IVY8@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
WH2_k127_4862081_1	1163617.SCD_n00417	5.165e-17	84.0	COG5001@1|root,COG5001@2|Bacteria,1QV5H@1224|Proteobacteria,2WGPI@28216|Betaproteobacteria	28216|Betaproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,LapD_MoxY_N
WH2_k127_4862081_0	1408433.JHXV01000008_gene111	5.816e-203	640.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1HX4B@117743|Flavobacteriia,2PADD@246874|Cryomorphaceae	976|Bacteroidetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WH2_k127_4862081_2	7918.ENSLOCP00000015121	3.884e-06	52.0	COG1282@1|root,2QQ0A@2759|Eukaryota,38CB0@33154|Opisthokonta,3BDQK@33208|Metazoa,3CWZ6@33213|Bilateria,4806D@7711|Chordata,494HY@7742|Vertebrata,4A2AF@7898|Actinopterygii	33208|Metazoa	C	Nicotinamide nucleotide transhydrogenase	NNT	GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009060,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016652,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019752,GO:0019866,GO:0022857,GO:0022890,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034220,GO:0034641,GO:0036094,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0048037,GO:0050661,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070469,GO:0071704,GO:0072350,GO:0072524,GO:0072593,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600	1.6.1.2	ko:K00323	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB,PNTB_4TM
WH2_k127_4879377_1	1046627.BZARG_1479	1.358e-41	155.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1HY3C@117743|Flavobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
WH2_k127_4879377_2	313606.M23134_06167	8.412e-34	139.0	COG1846@1|root,COG1846@2|Bacteria,4NNK7@976|Bacteroidetes,47QHS@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
WH2_k127_4879377_0	929556.Solca_3861	1.135e-87	312.0	28IZ7@1|root,2Z8WQ@2|Bacteria,4NIAK@976|Bacteroidetes,1IVBS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4879377_3	1297742.A176_01629	8.313e-26	120.0	COG2273@1|root,COG2273@2|Bacteria,1NFHX@1224|Proteobacteria,43AJK@68525|delta/epsilon subdivisions,2X5ZT@28221|Deltaproteobacteria,2YUVB@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
WH2_k127_4879377_4	1121912.AUHD01000004_gene2157	6.914e-12	69.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1I1B3@117743|Flavobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
WH2_k127_488200_0	1392490.JHZX01000001_gene385	2.769e-82	286.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1HX3D@117743|Flavobacteriia	976|Bacteroidetes	S	DHHA1 domain	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WH2_k127_488200_1	1408433.JHXV01000010_gene505	4.682e-26	117.0	COG0545@1|root,COG0545@2|Bacteria,4NV96@976|Bacteroidetes,1IC47@117743|Flavobacteriia,2PB8G@246874|Cryomorphaceae	976|Bacteroidetes	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
WH2_k127_4882332_0	1123277.KB893217_gene4672	3.921e-116	379.0	COG2192@1|root,COG2192@2|Bacteria,4NEV9@976|Bacteroidetes,47JR5@768503|Cytophagia	976|Bacteroidetes	O	PFAM Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
WH2_k127_4882332_5	391587.KAOT1_18412	4.394e-17	94.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	ko:K20306	-	-	-	-	ko00000,ko04131	-	-	-	Lipase_GDSL,Lipase_GDSL_2
WH2_k127_4882332_4	880071.Fleli_3929	4.263e-18	84.0	2EGPU@1|root,33AFZ@2|Bacteria,4NXYH@976|Bacteroidetes,47S90@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4882332_2	504472.Slin_4251	8.186e-20	93.0	2CH0Y@1|root,32S8V@2|Bacteria,4NSPM@976|Bacteroidetes,47RDF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4882332_1	421072.IO89_05200	2.487e-43	162.0	COG1694@1|root,COG1694@2|Bacteria,4NQ3H@976|Bacteroidetes,1I1Z0@117743|Flavobacteriia,3HI8P@358033|Chryseobacterium	976|Bacteroidetes	S	Phosphoribosyl-ATP pyrophosphohydrolase	ypjD	-	-	-	-	-	-	-	-	-	-	-	MazG
WH2_k127_4882332_3	2903.EOD06898	2.232e-18	96.0	28K1K@1|root,2QSG1@2759|Eukaryota	2903.EOD06898|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4915890_2	746697.Aeqsu_1344	0.0003753	52.0	COG1404@1|root,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,1I06M@117743|Flavobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Peptidase_S8
WH2_k127_4915890_1	1313301.AUGC01000001_gene1684	5.148e-05	55.0	COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes	976|Bacteroidetes	M	Outer membrane chaperone Skp	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
WH2_k127_4915890_0	1349822.NSB1T_08400	4.573e-28	122.0	2CGY7@1|root,2ZGS8@2|Bacteria,4NREX@976|Bacteroidetes,2FPIK@200643|Bacteroidia,22XT2@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4924
WH2_k127_4936545_1	1121373.KB903620_gene2055	0.0008496	48.0	2A79D@1|root,30W5Z@2|Bacteria,4NN88@976|Bacteroidetes,47RZT@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
WH2_k127_4936545_0	755732.Fluta_0895	3.888e-291	902.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1HX0U@117743|Flavobacteriia,2PAC8@246874|Cryomorphaceae	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
WH2_k127_494433_0	1223410.KN050846_gene1375	4.681e-123	409.0	COG2373@1|root,COG2373@2|Bacteria,4P17V@976|Bacteroidetes	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_494433_1	1122179.KB890436_gene1413	2.751e-57	210.0	COG3828@1|root,COG3828@2|Bacteria,4NDVK@976|Bacteroidetes	976|Bacteroidetes	C	trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	DUF1080,ThuA
WH2_k127_4949834_0	2423.NA23_0206420	3.244e-74	260.0	COG1933@1|root,COG1933@2|Bacteria,2GDRW@200918|Thermotogae	200918|Thermotogae	L	exodeoxyribonuclease I activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_4949834_2	1122621.ATZA01000009_gene240	8.171e-48	179.0	COG4948@1|root,COG4948@2|Bacteria,4NUSI@976|Bacteroidetes,1IUFR@117747|Sphingobacteriia	976|Bacteroidetes	M	Domain of unknown function (DUF4433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4433
WH2_k127_4949834_1	391596.PBAL39_20430	5.051e-54	192.0	COG2110@1|root,COG2110@2|Bacteria,4NJJG@976|Bacteroidetes,1IQ6G@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of histone	-	-	-	-	-	-	-	-	-	-	-	-	Macro
WH2_k127_4989070_1	1123400.KB904765_gene1396	2.865e-28	121.0	COG0823@1|root,COG1361@1|root,COG2706@1|root,COG2834@1|root,COG3291@1|root,COG5384@1|root,COG0823@2|Bacteria,COG1361@2|Bacteria,COG2706@2|Bacteria,COG2834@2|Bacteria,COG3291@2|Bacteria,COG5384@2|Bacteria,1QUSE@1224|Proteobacteria	1224|Proteobacteria	G	PFAM FecR protein	-	-	3.2.1.4	ko:K01179,ko:K03933	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	AA10,CBM73,GH5,GH9	-	CBM_2,Calx-beta,Cellulase,PKD
WH2_k127_4989070_0	1122165.AUHS01000047_gene3184	5.365e-65	241.0	COG1520@1|root,COG1520@2|Bacteria,1RBUT@1224|Proteobacteria,1S27R@1236|Gammaproteobacteria,1JEPR@118969|Legionellales	118969|Legionellales	DZ	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
WH2_k127_4990673_0	700598.Niako_3302	2.366e-89	315.0	COG1520@1|root,COG1520@2|Bacteria	700598.Niako_3302|-	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5008685_0	1185876.BN8_06695	7.365e-152	489.0	COG3239@1|root,COG3239@2|Bacteria,4NHPQ@976|Bacteroidetes,47KXE@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
WH2_k127_5008685_1	1313421.JHBV01000022_gene4705	3.063e-19	99.0	COG1196@1|root,COG2885@1|root,COG1196@2|Bacteria,COG2885@2|Bacteria,4NRRF@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
WH2_k127_5060767_0	1408433.JHXV01000014_gene3668	3.099e-284	907.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia,2PA61@246874|Cryomorphaceae	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
WH2_k127_5060767_2	1229276.DI53_1556	9.914e-52	186.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1IT1E@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
WH2_k127_5060767_3	391008.Smal_3428	7.761e-10	65.0	COG5652@1|root,COG5652@2|Bacteria,1NGE7@1224|Proteobacteria,1SGEP@1236|Gammaproteobacteria,1X7I7@135614|Xanthomonadales	135614|Xanthomonadales	S	PFAM VanZ	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
WH2_k127_5060767_1	1279009.ADICEAN_00540	3.129e-57	203.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,47KGK@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	-	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
WH2_k127_5066810_3	411477.PARMER_03358	9.296e-23	100.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,2FME2@200643|Bacteroidia,22XZ6@171551|Porphyromonadaceae	976|Bacteroidetes	M	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
WH2_k127_5066810_0	755732.Fluta_2221	1.272e-168	543.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1HY6Y@117743|Flavobacteriia,2PA5T@246874|Cryomorphaceae	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
WH2_k127_5066810_1	1408433.JHXV01000032_gene1131	9.584e-167	540.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1HWTE@117743|Flavobacteriia,2PADU@246874|Cryomorphaceae	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
WH2_k127_5066810_2	1121904.ARBP01000010_gene2301	7.45e-32	134.0	COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,47QJ2@768503|Cytophagia	976|Bacteroidetes	S	PFAM Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
WH2_k127_5067327_3	1121875.KB907547_gene3395	4.695e-12	67.0	2AFVV@1|root,315YK@2|Bacteria,4NQ4S@976|Bacteroidetes,1I2VI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5067327_2	395961.Cyan7425_0499	6.349e-28	116.0	COG4634@1|root,COG4634@2|Bacteria,1G6XU@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5067327_1	41431.PCC8801_1888	1.441e-28	117.0	COG2442@1|root,COG2442@2|Bacteria,1G869@1117|Cyanobacteria,3KIU5@43988|Cyanothece	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
WH2_k127_5067327_0	391596.PBAL39_20625	2.574e-120	390.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1INVI@117747|Sphingobacteriia	976|Bacteroidetes	D	DNA segregation ATPase FtsK SpoIIIE and related	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WH2_k127_507214_0	926562.Oweho_2065	5.244e-116	389.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,4NEIS@976|Bacteroidetes,1HXGB@117743|Flavobacteriia,2PBKD@246874|Cryomorphaceae	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	arlS_1	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WH2_k127_507214_1	929703.KE386491_gene3923	8.34e-76	259.0	COG0745@1|root,COG0745@2|Bacteria,4NE77@976|Bacteroidetes,47K3Z@768503|Cytophagia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WH2_k127_507214_2	331113.SNE_A14810	7.796e-05	47.0	COG1051@1|root,COG1051@2|Bacteria,2JGB9@204428|Chlamydiae	204428|Chlamydiae	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WH2_k127_5120905_0	1550091.JROE01000004_gene1372	1.298e-80	271.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,1IPBP@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WH2_k127_5120905_3	755732.Fluta_1898	4.846e-33	131.0	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,1I3VI@117743|Flavobacteriia,2PB4S@246874|Cryomorphaceae	976|Bacteroidetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
WH2_k127_5120905_4	1185876.BN8_04008	2.484e-26	109.0	COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes,47KJ2@768503|Cytophagia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WH2_k127_5120905_2	1185876.BN8_04008	1.913e-38	150.0	COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes,47KJ2@768503|Cytophagia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WH2_k127_5120905_1	1279009.ADICEAN_01874	6.97e-60	213.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,47KTP@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
WH2_k127_5121283_1	485918.Cpin_1909	1.726e-32	135.0	2CA60@1|root,2Z88P@2|Bacteria,4NJRW@976|Bacteroidetes,1IP54@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5121283_0	762903.Pedsa_1488	1.746e-140	452.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1IQ1P@117747|Sphingobacteriia	976|Bacteroidetes	C	Thioredoxin reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WH2_k127_5121283_2	984262.SGRA_1072	8.3e-18	91.0	2BG4X@1|root,33858@2|Bacteria,4NW0E@976|Bacteroidetes,1IUAK@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
WH2_k127_5125251_1	755732.Fluta_0694	1.971e-16	82.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1ICQ4@117743|Flavobacteriia,2PBNE@246874|Cryomorphaceae	976|Bacteroidetes	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
WH2_k127_5125251_0	1408433.JHXV01000018_gene3850	4.046e-57	219.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4P0PU@976|Bacteroidetes,1IMQT@117743|Flavobacteriia,2PBGH@246874|Cryomorphaceae	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5132011_1	596151.DesfrDRAFT_2710	3.71e-11	69.0	COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CZY@68525|delta/epsilon subdivisions,2X887@28221|Deltaproteobacteria,2MHCZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
WH2_k127_5132011_0	926562.Oweho_2308	2.449e-110	377.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia,2PBM8@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
WH2_k127_5161863_3	1166018.FAES_4636	8.05e-33	128.0	COG1216@1|root,COG1216@2|Bacteria,4PNB1@976|Bacteroidetes,47KU6@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH2_k127_5161863_1	1313301.AUGC01000017_gene823	2.644e-53	199.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes	976|Bacteroidetes	EG	of the drug metabolite transporter (DMT) superfamily	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
WH2_k127_5161863_4	1121897.AUGO01000001_gene1257	7.763e-07	58.0	COG2608@1|root,COG2608@2|Bacteria,4NS2K@976|Bacteroidetes,1I3FW@117743|Flavobacteriia,2NWRM@237|Flavobacterium	976|Bacteroidetes	P	heavy metal	-	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA
WH2_k127_5161863_0	1161401.ASJA01000009_gene1757	2.654e-84	293.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,43WQ7@69657|Hyphomonadaceae	28211|Alphaproteobacteria	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
WH2_k127_5161863_2	869213.JCM21142_93422	3.659e-34	138.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,47PUM@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated lipoprotein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5176358_0	755732.Fluta_2173	1.043e-223	703.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,1HYHI@117743|Flavobacteriia,2PA4M@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF3552)	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
WH2_k127_5176358_2	926562.Oweho_1280	3.042e-10	64.0	COG3027@1|root,COG3027@2|Bacteria,4NSA5@976|Bacteroidetes,1I41M@117743|Flavobacteriia,2PB8C@246874|Cryomorphaceae	976|Bacteroidetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
WH2_k127_5176358_3	1035197.HMPREF9999_02076	0.0001145	48.0	2ECU9@1|root,336RT@2|Bacteria,4NWF8@976|Bacteroidetes,2G1IH@200643|Bacteroidia,1WDN4@1283313|Alloprevotella	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5176358_1	411154.GFO_1878	8.911e-65	236.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1HXKD@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WH2_k127_5215313_1	313606.M23134_03684	2.521e-08	56.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,47M0Z@768503|Cytophagia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
WH2_k127_5215313_0	1120968.AUBX01000012_gene2821	3.465e-145	477.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,47KP4@768503|Cytophagia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WH2_k127_5216882_0	1121912.AUHD01000004_gene1999	4.682e-119	415.0	COG4386@1|root,COG4886@1|root,COG4386@2|Bacteria,COG4886@2|Bacteria,4PPDK@976|Bacteroidetes,1IKIZ@117743|Flavobacteriia	976|Bacteroidetes	E	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
WH2_k127_5227340_2	616991.JPOO01000003_gene1236	1.723e-71	273.0	COG0642@1|root,COG2205@2|Bacteria	616991.JPOO01000003_gene1236|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5227340_6	869213.JCM21142_104477	1.122e-28	126.0	COG2981@1|root,COG2981@2|Bacteria,4NHXY@976|Bacteroidetes,47SCF@768503|Cytophagia	976|Bacteroidetes	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
WH2_k127_5227340_0	880526.KE386488_gene1083	2.449e-184	592.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,2FMYF@200643|Bacteroidia,22UZK@171550|Rikenellaceae	976|Bacteroidetes	F	Adenylosuccinate lyase C-terminal	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
WH2_k127_5227340_4	1035193.HMPREF9073_00435	3.28e-54	197.0	COG2949@1|root,COG2949@2|Bacteria,4NNQS@976|Bacteroidetes,1I1DV@117743|Flavobacteriia,1EQR0@1016|Capnocytophaga	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	sanA	-	-	ko:K03748	-	-	-	-	ko00000	-	-	-	DUF218
WH2_k127_5227340_7	646529.Desaci_0797	5.08e-19	94.0	COG2318@1|root,COG2318@2|Bacteria,1V51W@1239|Firmicutes	1239|Firmicutes	S	DinB family	dinB	-	-	-	-	-	-	-	-	-	-	-	DinB
WH2_k127_5227340_5	755732.Fluta_0691	6.157e-34	141.0	2A21C@1|root,30QBC@2|Bacteria,4PGY1@976|Bacteroidetes,1IFSM@117743|Flavobacteriia,2PBPD@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5227340_1	755732.Fluta_4031	1.952e-169	546.0	COG0579@1|root,COG0579@2|Bacteria,4NE0B@976|Bacteroidetes,1HZQJ@117743|Flavobacteriia,2PACG@246874|Cryomorphaceae	976|Bacteroidetes	S	FAD dependent oxidoreductase	lhgO	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
WH2_k127_5227340_3	1185876.BN8_02817	3.393e-67	236.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,47JQM@768503|Cytophagia	976|Bacteroidetes	S	PFAM Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
WH2_k127_5243443_4	1270196.JCKI01000008_gene1441	2.455e-14	83.0	2A79D@1|root,30W5Z@2|Bacteria,4NN88@976|Bacteroidetes,1IRXG@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
WH2_k127_5243443_0	1408433.JHXV01000006_gene2698	2.179e-86	299.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,1HXJZ@117743|Flavobacteriia,2PAE7@246874|Cryomorphaceae	976|Bacteroidetes	G	Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
WH2_k127_5243443_1	1227739.Hsw_4282	3.852e-68	253.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,47MNB@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
WH2_k127_5243443_3	1124780.ANNU01000052_gene3564	4.393e-44	168.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,47QA8@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
WH2_k127_5243443_2	349102.Rsph17025_1487	1.387e-63	228.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2TQS1@28211|Alphaproteobacteria,1FBK9@1060|Rhodobacter	28211|Alphaproteobacteria	F	Signal transduction histidine kinase	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
WH2_k127_5245778_2	360910.BAV0084	1.83e-50	196.0	COG2244@1|root,COG2244@2|Bacteria,1MZWG@1224|Proteobacteria,2VU25@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
WH2_k127_5245778_1	1408433.JHXV01000024_gene1492	2.617e-77	280.0	COG1215@1|root,COG1215@2|Bacteria,4NT9I@976|Bacteroidetes,1ICDJ@117743|Flavobacteriia,2PB9X@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH2_k127_5245778_3	755732.Fluta_2179	7.773e-23	112.0	COG3307@1|root,COG3307@2|Bacteria,4NXNX@976|Bacteroidetes,1ICS9@117743|Flavobacteriia,2PBZ8@246874|Cryomorphaceae	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WH2_k127_5245778_0	755732.Fluta_2193	2.74e-114	378.0	COG0399@1|root,COG0399@2|Bacteria,4NFQ8@976|Bacteroidetes,1HZBY@117743|Flavobacteriia,2PBDW@246874|Cryomorphaceae	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
WH2_k127_5249116_3	925409.KI911562_gene1769	4.823e-24	107.0	COG0845@1|root,COG0845@2|Bacteria,4NITE@976|Bacteroidetes,1ISHH@117747|Sphingobacteriia	976|Bacteroidetes	M	SPTR Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,HlyD_D23
WH2_k127_5249116_1	984262.SGRA_2219	1.443e-62	227.0	COG2968@1|root,COG2968@2|Bacteria,4NKAQ@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF541)	-	-	-	-	-	-	-	-	-	-	-	-	SIMPL
WH2_k127_5249116_2	272562.CA_C2197	1.097e-26	124.0	COG2746@1|root,COG2746@2|Bacteria,1V2QD@1239|Firmicutes,249QB@186801|Clostridia,36HXI@31979|Clostridiaceae	186801|Clostridia	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
WH2_k127_5249116_6	1331060.RLDS_02225	4.57e-06	57.0	COG0454@1|root,COG0456@2|Bacteria,1N40K@1224|Proteobacteria,2UDSV@28211|Alphaproteobacteria,2K1FF@204457|Sphingomonadales	204457|Sphingomonadales	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WH2_k127_5249116_0	330214.NIDE2692	1.034e-118	402.0	COG1020@1|root,COG1020@2|Bacteria	2|Bacteria	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,DUF2172,DUF4910,HTH_47
WH2_k127_5249116_4	755732.Fluta_0942	8.283e-24	104.0	2BBSK@1|root,32XPV@2|Bacteria,4NSW3@976|Bacteroidetes,1IKDA@117743|Flavobacteriia,2PB42@246874|Cryomorphaceae	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
WH2_k127_5257314_0	1279009.ADICEAN_00940	2.235e-121	407.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,47MDC@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
WH2_k127_5266483_2	709991.Odosp_3063	1.123e-31	138.0	COG3762@1|root,COG3762@2|Bacteria,4NQIT@976|Bacteroidetes,2FTHS@200643|Bacteroidia,23091@171551|Porphyromonadaceae	976|Bacteroidetes	S	Pfam:TPM	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
WH2_k127_5266483_1	1237149.C900_00796	1.823e-65	230.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,47JGT@768503|Cytophagia	976|Bacteroidetes	S	PFAM LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
WH2_k127_5266483_0	1392489.JPOL01000002_gene2047	1.556e-81	276.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,1HXC4@117743|Flavobacteriia,2XIDC@283735|Leeuwenhoekiella	976|Bacteroidetes	E	Asparaginase	ybiK	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
WH2_k127_5267135_3	700598.Niako_4050	1.967e-47	179.0	COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes,1IY6E@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Lipid polyisoprenoid-binding, YceI-like	-	-	-	-	-	-	-	-	-	-	-	-	YceI
WH2_k127_5267135_1	1122176.KB903561_gene3593	4.846e-110	364.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1IXJN@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5267135_2	518766.Rmar_0832	2.34e-78	275.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,4NK8R@976|Bacteroidetes,1FIRK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
WH2_k127_5267135_4	1286632.P278_20710	5.686e-24	113.0	COG0589@1|root,COG0589@2|Bacteria,4NHXF@976|Bacteroidetes,1HY7W@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WH2_k127_5267135_0	1121904.ARBP01000002_gene6745	1.993e-118	391.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
WH2_k127_5291322_0	398720.MED217_14855	1.012e-70	244.0	COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,1HYQJ@117743|Flavobacteriia,2XIIR@283735|Leeuwenhoekiella	976|Bacteroidetes	S	O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
WH2_k127_5291322_2	1123037.AUDE01000019_gene3293	4.511e-11	70.0	2CYW5@1|root,32T50@2|Bacteria,4NS73@976|Bacteroidetes,1I3WS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5291322_1	700598.Niako_1153	3.496e-44	172.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,1IQZT@117747|Sphingobacteriia	976|Bacteroidetes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WH2_k127_5315188_0	391587.KAOT1_12767	5.405e-72	266.0	COG1345@1|root,COG3291@1|root,COG1345@2|Bacteria,COG3291@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia	976|Bacteroidetes	N	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	CUB,LTD,fn3
WH2_k127_5315685_0	1121875.KB907550_gene717	8.29e-73	264.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_12,TPR_8
WH2_k127_533538_1	755732.Fluta_3558	8.745e-32	134.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,1I942@117743|Flavobacteriia,2PBH5@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran
WH2_k127_533538_2	1408433.JHXV01000017_gene1628	1.079e-30	126.0	290ZX@1|root,2ZNMM@2|Bacteria,4P891@976|Bacteroidetes,1ICSI@117743|Flavobacteriia,2PC01@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_533538_0	1408433.JHXV01000017_gene1627	5.053e-43	170.0	29N3N@1|root,32D2M@2|Bacteria,4NRTM@976|Bacteroidetes,1ICPZ@117743|Flavobacteriia,2PBKH@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_533538_3	518766.Rmar_1073	2.705e-05	49.0	COG2133@1|root,COG2133@2|Bacteria,4NGG5@976|Bacteroidetes	976|Bacteroidetes	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
WH2_k127_5338965_3	1123242.JH636435_gene2852	1.897e-42	159.0	COG2326@1|root,COG2326@2|Bacteria,2IYWN@203682|Planctomycetes	203682|Planctomycetes	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
WH2_k127_5338965_5	1121374.KB891580_gene1810	1.882e-05	57.0	2C82W@1|root,32RHY@2|Bacteria,1RI7J@1224|Proteobacteria,1S72Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5338965_0	926562.Oweho_2103	2.961e-270	845.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,1HX3S@117743|Flavobacteriia,2PAHM@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
WH2_k127_5338965_2	760192.Halhy_4258	9.036e-51	195.0	COG0501@1|root,COG0501@2|Bacteria,4PP1T@976|Bacteroidetes,1J0XG@117747|Sphingobacteriia	976|Bacteroidetes	O	Zn-dependent protease contains TPR repeats	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
WH2_k127_5338965_1	1094466.KQS_00165	8.004e-110	364.0	COG4269@1|root,COG4269@2|Bacteria,4NI7F@976|Bacteroidetes,1I85H@117743|Flavobacteriia,2NTM3@237|Flavobacterium	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF898)	-	-	-	-	-	-	-	-	-	-	-	-	DUF898
WH2_k127_5338965_4	1408433.JHXV01000015_gene1792	1.348e-31	125.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,1IJBA@117743|Flavobacteriia,2PA8Z@246874|Cryomorphaceae	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
WH2_k127_5355663_1	1121904.ARBP01000009_gene4385	5.759e-08	63.0	2DMY6@1|root,32UCD@2|Bacteria,4NVHX@976|Bacteroidetes,47SQF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5355663_0	1408433.JHXV01000023_gene3302	6.736e-40	157.0	COG3291@1|root,COG3291@2|Bacteria,4PBW3@976|Bacteroidetes,1ICPP@117743|Flavobacteriia,2PBJ2@246874|Cryomorphaceae	976|Bacteroidetes	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA
WH2_k127_5361888_0	1408433.JHXV01000022_gene3142	6.276e-178	580.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5363946_1	926562.Oweho_2789	1.479e-88	311.0	COG1073@1|root,COG1073@2|Bacteria,4PM54@976|Bacteroidetes,1I69X@117743|Flavobacteriia	976|Bacteroidetes	S	Secretory lipase	-	-	-	-	-	-	-	-	-	-	-	-	LIP,Peptidase_S9
WH2_k127_5363946_0	1313421.JHBV01000042_gene3326	9.524e-174	560.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1IQGH@117747|Sphingobacteriia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
WH2_k127_5364856_0	755732.Fluta_2749	1.176e-168	533.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1HWVS@117743|Flavobacteriia,2PAHG@246874|Cryomorphaceae	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
WH2_k127_5364856_1	1279009.ADICEAN_02019	1.045e-125	417.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia	976|Bacteroidetes	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
WH2_k127_5379384_0	1123248.KB893319_gene4091	9.223e-22	110.0	COG3210@1|root,COG5295@1|root,COG3210@2|Bacteria,COG5295@2|Bacteria,4NT37@976|Bacteroidetes,1IZ6J@117747|Sphingobacteriia	976|Bacteroidetes	U	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
WH2_k127_5397972_0	1313301.AUGC01000004_gene2344	1.872e-53	210.0	COG1629@1|root,COG1629@2|Bacteria,4PKRK@976|Bacteroidetes	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WH2_k127_5398166_0	1123400.KB904765_gene1396	3.52e-36	154.0	COG0823@1|root,COG1361@1|root,COG2706@1|root,COG2834@1|root,COG3291@1|root,COG5384@1|root,COG0823@2|Bacteria,COG1361@2|Bacteria,COG2706@2|Bacteria,COG2834@2|Bacteria,COG3291@2|Bacteria,COG5384@2|Bacteria,1QUSE@1224|Proteobacteria	1224|Proteobacteria	G	PFAM FecR protein	-	-	3.2.1.4	ko:K01179,ko:K03933	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	AA10,CBM73,GH5,GH9	-	CBM_2,Calx-beta,Cellulase,PKD
WH2_k127_5412099_2	762903.Pedsa_3562	7.102e-46	169.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1IQD9@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	-	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
WH2_k127_5412099_1	926562.Oweho_2802	6.902e-59	219.0	COG0226@1|root,COG0226@2|Bacteria,4PKGM@976|Bacteroidetes	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
WH2_k127_5412099_0	927658.AJUM01000034_gene424	8.389e-147	475.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,2FPTN@200643|Bacteroidia,3XJTD@558415|Marinilabiliaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
WH2_k127_5419687_0	1121957.ATVL01000006_gene2744	2.409e-58	216.0	COG2272@1|root,COG2272@2|Bacteria,4PMEB@976|Bacteroidetes,47Y2U@768503|Cytophagia	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase
WH2_k127_5419687_1	1123057.P872_13775	1.282e-24	118.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,47JWQ@768503|Cytophagia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
WH2_k127_5419687_2	1227739.Hsw_2485	1.641e-16	79.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,47JD1@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM flavoprotein, HI0933 family	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
WH2_k127_5436941_0	929556.Solca_3388	2.56e-77	275.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1IPC5@117747|Sphingobacteriia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WH2_k127_5436941_2	742725.HMPREF9450_00040	3.223e-27	121.0	COG1595@1|root,COG1595@2|Bacteria,4NQ7S@976|Bacteroidetes,2FTDI@200643|Bacteroidia,22VJZ@171550|Rikenellaceae	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH2_k127_5436941_1	1120965.AUBV01000008_gene1981	2.863e-32	126.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,47KNQ@768503|Cytophagia	976|Bacteroidetes	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
WH2_k127_5437762_2	861299.J421_1701	6.966e-15	80.0	COG1696@1|root,COG1696@2|Bacteria,1ZV39@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
WH2_k127_5437762_0	391587.KAOT1_18802	1.777e-176	565.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia	976|Bacteroidetes	M	Membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
WH2_k127_5437795_1	1237149.C900_05754	4.488e-56	205.0	COG2503@1|root,COG2503@2|Bacteria,4NJIJ@976|Bacteroidetes	976|Bacteroidetes	S	5'-nucleotidase, lipoprotein e(P4) family	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
WH2_k127_5437795_0	926562.Oweho_2845	1.765e-68	239.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1HX6Y@117743|Flavobacteriia,2PADM@246874|Cryomorphaceae	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
WH2_k127_545100_1	1453500.AT05_00460	8.675e-17	91.0	2BVGH@1|root,32QVC@2|Bacteria,4NQ4G@976|Bacteroidetes,1IB3J@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_545100_0	203275.BFO_1892	3.972e-42	173.0	COG0609@1|root,COG0609@2|Bacteria,4NEDU@976|Bacteroidetes,2FNDK@200643|Bacteroidia,22WJI@171551|Porphyromonadaceae	976|Bacteroidetes	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
WH2_k127_5459232_2	485917.Phep_0285	1.121e-48	178.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,1IRXU@117747|Sphingobacteriia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
WH2_k127_5459232_1	1288963.ADIS_0083	4.873e-56	204.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,47P8Y@768503|Cytophagia	976|Bacteroidetes	S	PFAM Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
WH2_k127_5459232_3	709991.Odosp_1010	4.589e-36	139.0	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,2FTSK@200643|Bacteroidia,22YD9@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
WH2_k127_5459232_0	1168034.FH5T_18730	0.0	1091.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,2FMVF@200643|Bacteroidia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WH2_k127_5495249_0	406124.ACPC01000018_gene2709	1.599e-83	287.0	COG0604@1|root,COG0604@2|Bacteria,1TSWF@1239|Firmicutes,4HANV@91061|Bacilli,1ZPZP@1386|Bacillus	91061|Bacilli	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
WH2_k127_5504695_1	1408433.JHXV01000015_gene1713	1.393e-75	263.0	COG3920@1|root,COG3920@2|Bacteria,4NM3G@976|Bacteroidetes,1I0XX@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,PAS_9
WH2_k127_5504695_0	1408433.JHXV01000015_gene1712	4.27e-115	375.0	COG3279@1|root,COG3279@2|Bacteria,4NKXC@976|Bacteroidetes,1I0BK@117743|Flavobacteriia,2PAUQ@246874|Cryomorphaceae	976|Bacteroidetes	K	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
WH2_k127_551749_6	1242864.D187_003246	5.841e-22	100.0	COG5646@1|root,COG5646@2|Bacteria,1R0CX@1224|Proteobacteria,43CVJ@68525|delta/epsilon subdivisions,2X83I@28221|Deltaproteobacteria,2YVP8@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WH2_k127_551749_2	697282.Mettu_0557	2.966e-43	162.0	COG4978@1|root,COG4978@2|Bacteria,1N06E@1224|Proteobacteria,1SFTG@1236|Gammaproteobacteria,1XGBH@135618|Methylococcales	135618|Methylococcales	KT	PFAM Bacterial transcription activator, effector binding	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
WH2_k127_551749_5	69395.JQLZ01000006_gene2054	2.243e-24	106.0	COG5646@1|root,COG5646@2|Bacteria,1NKMZ@1224|Proteobacteria,2UJHW@28211|Alphaproteobacteria,2KJ5I@204458|Caulobacterales	204458|Caulobacterales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WH2_k127_551749_3	760192.Halhy_4897	1.327e-30	126.0	COG2259@1|root,31BQE@2|Bacteria,4PQ0A@976|Bacteroidetes,1J0F3@117747|Sphingobacteriia	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
WH2_k127_551749_4	1288494.EBAPG3_17370	2.076e-30	126.0	COG3832@1|root,COG3832@2|Bacteria,1RJ1C@1224|Proteobacteria,2WEK0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
WH2_k127_551749_0	580332.Slit_1984	6.867e-80	273.0	COG2085@1|root,COG2085@2|Bacteria,1NI54@1224|Proteobacteria,2VNIB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
WH2_k127_551749_1	926562.Oweho_1183	3.516e-56	198.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,1HWKT@117743|Flavobacteriia,2PAC4@246874|Cryomorphaceae	976|Bacteroidetes	S	MazG nucleotide pyrophosphohydrolase domain	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
WH2_k127_5549390_0	1408433.JHXV01000001_gene996	1.78e-74	273.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia,2PA9P@246874|Cryomorphaceae	976|Bacteroidetes	L	UvrD/REP helicase N-terminal domain	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
WH2_k127_557333_0	926562.Oweho_2448	1.02e-180	585.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HXWX@117743|Flavobacteriia,2PAGV@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Penicillin binding protein transpeptidase domain	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
WH2_k127_557333_2	742726.HMPREF9448_02363	3.923e-26	114.0	2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,2FUJF@200643|Bacteroidia,22YQC@171551|Porphyromonadaceae	976|Bacteroidetes	S	GldH lipoprotein	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	GldH_lipo
WH2_k127_557333_1	755732.Fluta_1637	2.828e-67	238.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1HXPY@117743|Flavobacteriia,2PA4Y@246874|Cryomorphaceae	976|Bacteroidetes	S	PSP1 C-terminal conserved region	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
WH2_k127_5582566_0	543632.JOJL01000021_gene949	0.0003577	53.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4DBE3@85008|Micromonosporales	201174|Actinobacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
WH2_k127_5604488_0	1408473.JHXO01000010_gene3748	9.793e-90	314.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,2FMKE@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
WH2_k127_5665328_0	926562.Oweho_2365	4.068e-103	365.0	COG1729@1|root,COG1729@2|Bacteria,4PKGA@976|Bacteroidetes,1IKHB@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
WH2_k127_5666630_1	1185876.BN8_05774	2.645e-29	123.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,47R7Q@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
WH2_k127_5666630_3	1033732.CAHI01000024_gene778	1.572e-09	68.0	COG0810@1|root,COG0810@2|Bacteria,4NWAV@976|Bacteroidetes,2G0KV@200643|Bacteroidia,22UKT@171550|Rikenellaceae	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
WH2_k127_5666630_0	203275.BFO_2019	4.261e-76	271.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,4NEV7@976|Bacteroidetes,2FKZX@200643|Bacteroidia,22WT9@171551|Porphyromonadaceae	976|Bacteroidetes	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA
WH2_k127_5666630_2	1448857.JFAP01000003_gene1552	7.663e-16	79.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2YMCM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
WH2_k127_5683037_0	643867.Ftrac_2414	1.781e-64	240.0	28ICP@1|root,2Z8EZ@2|Bacteria,4NKKI@976|Bacteroidetes,47N2N@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5683037_1	1385935.N836_33000	2.01e-33	142.0	COG0500@1|root,COG2226@2|Bacteria,1GQNU@1117|Cyanobacteria,1HHXR@1150|Oscillatoriales	1117|Cyanobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
WH2_k127_5699996_0	1121335.Clst_1990	1.752e-32	131.0	2BWJ3@1|root,2Z7IQ@2|Bacteria,1VRTV@1239|Firmicutes,24H21@186801|Clostridia	186801|Clostridia	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
WH2_k127_5699996_1	1254432.SCE1572_37250	2.021e-21	108.0	COG1020@1|root,COG1020@2|Bacteria,1NK69@1224|Proteobacteria,42Z6P@68525|delta/epsilon subdivisions,2WUP2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5699996_2	1410674.JNKU01000001_gene192	0.0001659	47.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
WH2_k127_5705740_3	745718.JADT01000015_gene2904	4.939e-65	235.0	COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,1HXJW@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
WH2_k127_5705740_0	313596.RB2501_12357	7.048e-175	557.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,1HXAZ@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
WH2_k127_5705740_2	1453500.AT05_02940	5.924e-94	321.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,1HWXZ@117743|Flavobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
WH2_k127_5705740_5	391596.PBAL39_18769	2.053e-40	152.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,1IT08@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, ArsR family protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
WH2_k127_5705740_1	485918.Cpin_6112	5.102e-120	395.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	arsM	-	2.1.1.137,2.1.1.79	ko:K00574,ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
WH2_k127_5705740_4	880070.Cycma_1211	2.203e-64	231.0	COG0394@1|root,COG0394@2|Bacteria,4NE8C@976|Bacteroidetes,47PXK@768503|Cytophagia	976|Bacteroidetes	T	PFAM Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1,3.1.3.48	ko:K01104,ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
WH2_k127_5706570_2	755732.Fluta_0604	2.581e-28	132.0	COG1357@1|root,COG3291@1|root,COG3405@1|root,COG4412@1|root,COG1357@2|Bacteria,COG3291@2|Bacteria,COG3405@2|Bacteria,COG4412@2|Bacteria,4NMVW@976|Bacteroidetes,1I1JQ@117743|Flavobacteriia,2PBI2@246874|Cryomorphaceae	976|Bacteroidetes	G	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
WH2_k127_5706570_3	468059.AUHA01000002_gene386	2.587e-09	70.0	COG1361@1|root,COG5492@1|root,COG1361@2|Bacteria,COG5492@2|Bacteria,4PHWR@976|Bacteroidetes,1IYRV@117747|Sphingobacteriia	976|Bacteroidetes	MN	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
WH2_k127_5706570_1	1313421.JHBV01000031_gene1344	4.118e-76	279.0	COG0265@1|root,COG3209@1|root,COG3291@1|root,COG0265@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,4PKT1@976|Bacteroidetes	976|Bacteroidetes	O	COG3209 Rhs family protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
WH2_k127_5706570_0	1121904.ARBP01000004_gene802	1.665e-113	383.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,47MDC@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
WH2_k127_5728966_2	755732.Fluta_2237	3.887e-82	278.0	COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,1HX32@117743|Flavobacteriia,2PBNQ@246874|Cryomorphaceae	976|Bacteroidetes	F	Uracil phosphoribosyltransferase	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
WH2_k127_5728966_5	1408473.JHXO01000010_gene3653	1.046e-26	121.0	COG5653@1|root,COG5653@2|Bacteria,4NQN5@976|Bacteroidetes,2FT4P@200643|Bacteroidia	976|Bacteroidetes	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
WH2_k127_5728966_4	313594.PI23P_00765	4.126e-56	215.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1HWXT@117743|Flavobacteriia,3VV44@52959|Polaribacter	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5728966_1	1453500.AT05_02205	2.506e-87	302.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	pelE	-	3.4.11.10,3.4.11.6,4.2.2.2	ko:K01728,ko:K19701	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000,ko01002	-	-	-	CBM_2,CBM_6,Pec_lyase,Prenyltrans
WH2_k127_5728966_0	1123277.KB893244_gene5131	1.007e-94	324.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,47U25@768503|Cytophagia	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.23	ko:K13019	ko00520,map00520	-	R09600	RC00290	ko00000,ko00001,ko01000,ko01005	-	-	-	Epimerase_2
WH2_k127_5728966_3	313606.M23134_01329	7.611e-74	255.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,47KTY@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
WH2_k127_5728966_6	983544.Lacal_0344	6.25e-26	108.0	COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,1I3XI@117743|Flavobacteriia	976|Bacteroidetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
WH2_k127_5728966_7	743722.Sph21_2035	6.061e-10	59.0	COG2148@1|root,COG2148@2|Bacteria,4NER4@976|Bacteroidetes,1IPFF@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Bacterial sugar transferase	-	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
WH2_k127_5731513_0	1121957.ATVL01000011_gene3727	3.207e-39	150.0	COG0815@1|root,COG0815@2|Bacteria,4NG4X@976|Bacteroidetes,47JV8@768503|Cytophagia	976|Bacteroidetes	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
WH2_k127_5731513_1	1356852.N008_09270	5.42e-20	105.0	COG2911@1|root,COG3391@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,4NSPG@976|Bacteroidetes,47V9V@768503|Cytophagia	976|Bacteroidetes	O	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5731513_2	1237149.C900_05117	1.835e-19	97.0	COG0147@1|root,COG0147@2|Bacteria,4NECR@976|Bacteroidetes,47K5D@768503|Cytophagia	976|Bacteroidetes	EH	Anthranilate para-aminobenzoate synthase component I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
WH2_k127_5745552_0	1408433.JHXV01000002_gene458	1.767e-88	318.0	COG4447@1|root,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,1HYZP@117743|Flavobacteriia,2PBDK@246874|Cryomorphaceae	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5754101_1	553171.HMPREF0648_1024	4.435e-31	125.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,2FS1V@200643|Bacteroidia	976|Bacteroidetes	S	Hydrolase, P-loop family	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
WH2_k127_5754101_0	391596.PBAL39_11637	1.631e-155	500.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,1IP34@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
WH2_k127_5756467_0	1434325.AZQN01000001_gene594	2.059e-111	374.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,47KFN@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
WH2_k127_5756467_2	1121373.KB903643_gene3461	2.316e-07	60.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
WH2_k127_5756467_1	1121129.KB903360_gene3569	1.007e-107	357.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,2FMV1@200643|Bacteroidia,22WQI@171551|Porphyromonadaceae	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
WH2_k127_5763150_1	483216.BACEGG_01173	2.473e-11	69.0	COG5263@1|root,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
WH2_k127_5763150_0	760192.Halhy_0214	6.385e-88	314.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,4PN79@976|Bacteroidetes	976|Bacteroidetes	G	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
WH2_k127_5763940_1	269798.CHU_2418	4.167e-77	264.0	COG0009@1|root,COG0009@2|Bacteria,4NF5U@976|Bacteroidetes,47KX9@768503|Cytophagia	976|Bacteroidetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua5	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
WH2_k127_5763940_2	997352.HMPREF9419_1365	2.591e-06	56.0	COG3184@1|root,COG3184@2|Bacteria,4NSCK@976|Bacteroidetes	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09924	-	-	-	-	ko00000	-	-	-	DUF2059
WH2_k127_5763940_0	1124780.ANNU01000008_gene2637	5.526e-128	416.0	COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,47K0A@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
WH2_k127_5767676_3	1453500.AT05_04920	2.132e-54	201.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1HYEQ@117743|Flavobacteriia	976|Bacteroidetes	S	Outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
WH2_k127_5767676_4	1121094.KB894650_gene2475	1.698e-31	128.0	2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,2FTC9@200643|Bacteroidia,4AQY4@815|Bacteroidaceae	976|Bacteroidetes	S	COG NOG14434 non supervised orthologous group	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
WH2_k127_5767676_0	1008457.BAEX01000041_gene2737	7.86e-124	415.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1HWSS@117743|Flavobacteriia,47H9G@76831|Myroides	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
WH2_k127_5767676_1	869213.JCM21142_3856	1.221e-72	267.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,47N7V@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
WH2_k127_5767676_2	1408473.JHXO01000013_gene529	5.469e-65	237.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,2FMIG@200643|Bacteroidia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
WH2_k127_58016_1	755732.Fluta_0853	1.071e-61	224.0	COG4775@1|root,COG4775@2|Bacteria,4NF35@976|Bacteroidetes,1HZII@117743|Flavobacteriia,2PB09@246874|Cryomorphaceae	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA,ShlB
WH2_k127_58016_2	1279019.ARQK01000058_gene659	4.832e-42	166.0	COG1376@1|root,COG1376@2|Bacteria,1MYZT@1224|Proteobacteria,1S8PS@1236|Gammaproteobacteria,1WY8E@135613|Chromatiales	135613|Chromatiales	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
WH2_k127_58016_0	1121930.AQXG01000001_gene1468	5.283e-101	346.0	COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,1INWB@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
WH2_k127_5830255_4	1121895.Q765_13330	1.59e-07	66.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4NF8H@976|Bacteroidetes,1IJ61@117743|Flavobacteriia	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,MAM,Peptidase_M14,Reprolysin_4,fn3
WH2_k127_5830255_2	1122176.KB903587_gene4485	9.232e-19	103.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,4PPP2@976|Bacteroidetes,1IZ5Q@117747|Sphingobacteriia	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5830255_1	1237149.C900_03944	7.446e-28	133.0	COG1404@1|root,COG1404@2|Bacteria,4PM4C@976|Bacteroidetes,47KZM@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	MAM,Peptidase_S8,fn3
WH2_k127_5830255_0	1123400.KB904765_gene1396	9.331e-45	188.0	COG0823@1|root,COG1361@1|root,COG2706@1|root,COG2834@1|root,COG3291@1|root,COG5384@1|root,COG0823@2|Bacteria,COG1361@2|Bacteria,COG2706@2|Bacteria,COG2834@2|Bacteria,COG3291@2|Bacteria,COG5384@2|Bacteria,1QUSE@1224|Proteobacteria	1224|Proteobacteria	G	PFAM FecR protein	-	-	3.2.1.4	ko:K01179,ko:K03933	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	AA10,CBM73,GH5,GH9	-	CBM_2,Calx-beta,Cellulase,PKD
WH2_k127_5830255_3	869213.JCM21142_1689	1.437e-15	80.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,47NU9@768503|Cytophagia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH2_k127_5838597_0	313596.RB2501_07270	8.602e-77	264.0	COG0446@1|root,COG0446@2|Bacteria,4NEK6@976|Bacteroidetes,1HZW9@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WH2_k127_5838597_1	269798.CHU_0676	4.038e-54	193.0	COG2353@1|root,COG2353@2|Bacteria,4NNMD@976|Bacteroidetes,47P9R@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
WH2_k127_5847262_2	864702.OsccyDRAFT_3481	2.85e-24	105.0	COG1840@1|root,COG1840@2|Bacteria,1G0PQ@1117|Cyanobacteria,1H90N@1150|Oscillatoriales	1117|Cyanobacteria	P	ABC-type Fe3 transport system, periplasmic component	afuA	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	iJN678.sufA	SBP_bac_6,SBP_bac_8
WH2_k127_5847262_0	589865.DaAHT2_2225	3.09e-105	360.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,42PE3@68525|delta/epsilon subdivisions,2WKM3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
WH2_k127_5847262_4	1089547.KB913013_gene124	0.0002093	49.0	2EGC0@1|root,331VR@2|Bacteria,4NWM2@976|Bacteroidetes,47S8W@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5847262_3	682795.AciX8_0041	4.545e-24	109.0	COG2318@1|root,COG2318@2|Bacteria,3Y81K@57723|Acidobacteria,2JN5E@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WH2_k127_5847262_1	1250232.JQNJ01000001_gene237	1.413e-30	121.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,1HXV3@117743|Flavobacteriia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WH2_k127_5852563_3	153721.MYP_2331	1.452e-44	178.0	COG2755@1|root,COG3291@1|root,COG2755@2|Bacteria,COG3291@2|Bacteria,4PHTU@976|Bacteroidetes,47P4N@768503|Cytophagia	976|Bacteroidetes	E	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
WH2_k127_5852563_0	755732.Fluta_3279	8.395e-167	542.0	COG1249@1|root,COG1249@2|Bacteria,4NJ2P@976|Bacteroidetes,1IGB0@117743|Flavobacteriia,2PBK6@246874|Cryomorphaceae	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
WH2_k127_5852563_1	1453500.AT05_08620	6.405e-100	342.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1HXUF@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
WH2_k127_5852563_2	984262.SGRA_4195	7.895e-53	190.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes	976|Bacteroidetes	C	cytochrome C peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
WH2_k127_5852776_0	1408433.JHXV01000020_gene3544	2.454e-138	458.0	COG1629@1|root,COG4771@2|Bacteria,4NTQD@976|Bacteroidetes,1IKD4@117743|Flavobacteriia,2PA9C@246874|Cryomorphaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
WH2_k127_586701_0	929556.Solca_0687	4.46e-133	430.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1J0YT@117747|Sphingobacteriia	976|Bacteroidetes	I	Biotin carboxylase C-terminal domain	accC	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
WH2_k127_586701_1	927658.AJUM01000024_gene2548	1.971e-36	151.0	2CI1G@1|root,2Z7JA@2|Bacteria,4NF1T@976|Bacteroidetes,2FPFD@200643|Bacteroidia,3XJ9A@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4294
WH2_k127_5872225_0	103690.17132052	1.209e-22	102.0	COG2442@1|root,COG2442@2|Bacteria,1G7V4@1117|Cyanobacteria,1HP8S@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
WH2_k127_5872225_2	1313421.JHBV01000031_gene1379	0.0001348	45.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,1IPE0@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
WH2_k127_588044_1	1501391.LG35_03525	8.998e-77	259.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,2FN99@200643|Bacteroidia,22UY5@171550|Rikenellaceae	976|Bacteroidetes	J	Seryl-tRNA synthetase N-terminal domain	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
WH2_k127_588044_0	1313421.JHBV01000024_gene4970	6.365e-116	404.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE2V@976|Bacteroidetes,1INS7@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6,TPR_8
WH2_k127_588044_2	643867.Ftrac_1475	0.0002017	51.0	2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,47RVQ@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4286)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4286
WH2_k127_5891163_5	7230.FBpp0159780	0.0006683	53.0	28KG1@1|root,2QSX8@2759|Eukaryota,38GTW@33154|Opisthokonta,3BDQP@33208|Metazoa,3CRW8@33213|Bilateria,41WSR@6656|Arthropoda,3SI7W@50557|Insecta,4509B@7147|Diptera,45TAN@7214|Drosophilidae	33208|Metazoa	O	copper ion binding. It is involved in the biological process described with oxidation-reduction process	LOXL4	GO:0000122,GO:0000785,GO:0001501,GO:0001525,GO:0001568,GO:0001666,GO:0001667,GO:0001837,GO:0001935,GO:0001944,GO:0001968,GO:0002040,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0002697,GO:0002698,GO:0002819,GO:0002820,GO:0002822,GO:0002823,GO:0003674,GO:0003824,GO:0004720,GO:0005488,GO:0005507,GO:0005509,GO:0005515,GO:0005575,GO:0005576,GO:0005604,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005783,GO:0006091,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006807,GO:0006928,GO:0006950,GO:0006952,GO:0006954,GO:0006996,GO:0007155,GO:0007162,GO:0007275,GO:0007399,GO:0007417,GO:0007568,GO:0008150,GO:0008152,GO:0008283,GO:0009055,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009966,GO:0009967,GO:0009987,GO:0010035,GO:0010038,GO:0010453,GO:0010454,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010631,GO:0010646,GO:0010647,GO:0010717,GO:0010718,GO:0012505,GO:0016043,GO:0016477,GO:0016491,GO:0016638,GO:0016641,GO:0018057,GO:0018158,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019538,GO:0021510,GO:0022407,GO:0022408,GO:0022610,GO:0022900,GO:0023051,GO:0023056,GO:0030154,GO:0030155,GO:0030198,GO:0030199,GO:0030246,GO:0030323,GO:0030324,GO:0031012,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031974,GO:0031981,GO:0032330,GO:0032332,GO:0032501,GO:0032502,GO:0032991,GO:0035239,GO:0035295,GO:0036211,GO:0036293,GO:0040011,GO:0042221,GO:0043009,GO:0043062,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043235,GO:0043370,GO:0043371,GO:0043412,GO:0043542,GO:0043933,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045580,GO:0045581,GO:0045595,GO:0045596,GO:0045597,GO:0045619,GO:0045620,GO:0045622,GO:0045623,GO:0045892,GO:0045934,GO:0046634,GO:0046636,GO:0046637,GO:0046639,GO:0046688,GO:0046872,GO:0046914,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048585,GO:0048598,GO:0048646,GO:0048701,GO:0048703,GO:0048704,GO:0048705,GO:0048706,GO:0048731,GO:0048762,GO:0048856,GO:0048869,GO:0048870,GO:0050673,GO:0050776,GO:0050777,GO:0050789,GO:0050793,GO:0050794,GO:0050863,GO:0050865,GO:0050866,GO:0050868,GO:0050896,GO:0051093,GO:0051094,GO:0051171,GO:0051172,GO:0051179,GO:0051239,GO:0051240,GO:0051241,GO:0051249,GO:0051250,GO:0051252,GO:0051253,GO:0051276,GO:0051674,GO:0055114,GO:0060021,GO:0060255,GO:0060429,GO:0060485,GO:0060541,GO:0061035,GO:0061036,GO:0061053,GO:0062023,GO:0065007,GO:0070013,GO:0070482,GO:0070492,GO:0070828,GO:0071704,GO:0071840,GO:0072358,GO:0072359,GO:0080090,GO:0090130,GO:0090132,GO:0097435,GO:0140096,GO:1901564,GO:1902105,GO:1902106,GO:1902455,GO:1902679,GO:1903037,GO:1903038,GO:1903506,GO:1903507,GO:1903706,GO:1903707,GO:1904888,GO:1905590,GO:2000026,GO:2000036,GO:2000112,GO:2000113,GO:2000316,GO:2000317,GO:2000319,GO:2000320,GO:2000328,GO:2000329,GO:2000514,GO:2000515,GO:2001044,GO:2001046,GO:2001141	1.4.3.13	ko:K00277,ko:K00280	-	-	-	-	ko00000,ko01000	-	-	-	Lysyl_oxidase,SRCR
WH2_k127_5891163_0	984262.SGRA_1212	1.967e-28	133.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NFMW@976|Bacteroidetes,1IU7A@117747|Sphingobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Peptidase_S8
WH2_k127_5891163_4	926562.Oweho_3428	1.832e-05	58.0	COG3291@1|root,COG3291@2|Bacteria,4NI4A@976|Bacteroidetes,1I44J@117743|Flavobacteriia	976|Bacteroidetes	L	MAM domain, meprin/A5/mu	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,fn3
WH2_k127_5891163_3	330214.NIDE2245	2.091e-15	90.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Fer4_4,Fer4_5,Fer4_9
WH2_k127_5891163_1	1296416.JACB01000001_gene3343	1.677e-26	117.0	COG2010@1|root,COG2010@2|Bacteria,4NRFW@976|Bacteroidetes,1I3K8@117743|Flavobacteriia,2YKQM@290174|Aquimarina	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
WH2_k127_5891163_2	1121889.AUDM01000010_gene615	3.033e-17	92.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1HXMD@117743|Flavobacteriia,2NSAQ@237|Flavobacterium	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5914243_1	927658.AJUM01000037_gene2452	1.81e-33	150.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,2FRVJ@200643|Bacteroidia,3XIZ5@558415|Marinilabiliaceae	976|Bacteroidetes	T	GHKL domain	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WH2_k127_5914243_0	1313421.JHBV01000042_gene3261	8.388e-92	318.0	COG2353@1|root,COG3210@1|root,COG2353@2|Bacteria,COG3210@2|Bacteria,4NIDX@976|Bacteroidetes	976|Bacteroidetes	U	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
WH2_k127_5922474_0	1168034.FH5T_01600	8.22e-247	769.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,2FMNU@200643|Bacteroidia	976|Bacteroidetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
WH2_k127_5933538_1	391587.KAOT1_10501	2.259e-30	123.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,YkuD
WH2_k127_5933538_2	391038.Bphy_3577	1.262e-29	123.0	COG1661@1|root,COG1661@2|Bacteria,1RIME@1224|Proteobacteria,2VTIC@28216|Betaproteobacteria,1K8BC@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
WH2_k127_5933538_0	992406.RIA_1604	6.066e-60	213.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,1HYJ9@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
WH2_k127_5933538_3	751994.AGIG01000028_gene1887	2.451e-12	70.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477	ATP-grasp
WH2_k127_5943382_1	1191523.MROS_0081	0.0003098	51.0	COG0737@1|root,COG3291@1|root,COG0737@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	xynX5	-	3.2.1.4,3.2.1.8	ko:K01179,ko:K01181	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Beta_helix,IgGFc_binding,Metallophos,PKD,SLH
WH2_k127_5943382_0	1120951.AUBG01000007_gene55	2.959e-07	62.0	COG1345@1|root,COG3227@1|root,COG1345@2|Bacteria,COG3227@2|Bacteria,4NGSK@976|Bacteroidetes,1HXWK@117743|Flavobacteriia	976|Bacteroidetes	N	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Flg_new,LTD
WH2_k127_5944475_0	1305737.JAFX01000001_gene3478	3.74e-50	198.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,47K9X@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
WH2_k127_5944475_1	1408433.JHXV01000016_gene1829	1.837e-10	65.0	COG2146@1|root,COG2146@2|Bacteria,4NV9E@976|Bacteroidetes	976|Bacteroidetes	P	PFAM Rieske 2Fe-2S	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske,Rieske_2
WH2_k127_5955402_1	1453500.AT05_06190	3.319e-48	176.0	2BJ0K@1|root,32D95@2|Bacteria,4NQN9@976|Bacteroidetes,1I94U@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_5955402_0	1408433.JHXV01000017_gene1578	3.111e-163	532.0	COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,1HWS6@117743|Flavobacteriia,2PAF1@246874|Cryomorphaceae	976|Bacteroidetes	GM	PFAM Polysaccharide biosynthesis protein	wbpM	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
WH2_k127_5989202_0	1406840.Q763_04435	4.357e-37	157.0	COG4872@1|root,COG4872@2|Bacteria,4NIK7@976|Bacteroidetes,1HZVF@117743|Flavobacteriia,2NYDP@237|Flavobacterium	976|Bacteroidetes	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
WH2_k127_5989202_1	523791.Kkor_1758	1.646e-17	89.0	COG4929@1|root,COG4929@2|Bacteria,1NCJA@1224|Proteobacteria	1224|Proteobacteria	S	GDYXXLXY protein	-	-	-	-	-	-	-	-	-	-	-	-	GDYXXLXY
WH2_k127_6002319_3	388413.ALPR1_19828	9.561e-97	319.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,47JQ7@768503|Cytophagia	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
WH2_k127_6002319_5	869213.JCM21142_93878	7.079e-50	191.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47JZP@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
WH2_k127_6002319_6	761193.Runsl_3072	6.525e-44	168.0	COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,47QCT@768503|Cytophagia	976|Bacteroidetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
WH2_k127_6002319_0	755732.Fluta_0235	5.91e-142	459.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,1HXKY@117743|Flavobacteriia,2PAIS@246874|Cryomorphaceae	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WH2_k127_6002319_2	1185876.BN8_02947	7.15e-102	338.0	COG1398@1|root,COG1398@2|Bacteria,4NE0I@976|Bacteroidetes,47KJ0@768503|Cytophagia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
WH2_k127_6002319_4	1089547.KB913013_gene625	6.965e-53	198.0	COG0008@1|root,COG0008@2|Bacteria,4NP0Y@976|Bacteroidetes,47Q0Q@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WH2_k127_6002319_7	411477.PARMER_01457	1.841e-07	60.0	2DFVK@1|root,2ZTBH@2|Bacteria,4PIGB@976|Bacteroidetes,2G1SY@200643|Bacteroidia,2318W@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6002319_1	313596.RB2501_03380	6.41e-110	361.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1HX43@117743|Flavobacteriia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WH2_k127_6030894_0	1237149.C900_03056	0.0	1020.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,47KF9@768503|Cytophagia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
WH2_k127_6035467_0	1121904.ARBP01000009_gene4385	4.434e-19	100.0	2DMY6@1|root,32UCD@2|Bacteria,4NVHX@976|Bacteroidetes,47SQF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6066301_2	745718.JADT01000015_gene2925	2.644e-41	165.0	COG3210@1|root,COG3210@2|Bacteria,4NIDX@976|Bacteroidetes,1I0AY@117743|Flavobacteriia	976|Bacteroidetes	U	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
WH2_k127_6066301_1	1123057.P872_08590	8.749e-52	190.0	COG2318@1|root,COG2318@2|Bacteria,4NNQI@976|Bacteroidetes,47QCG@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	yfiT	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WH2_k127_6066301_3	929713.NIASO_04350	2.242e-07	58.0	COG1848@1|root,COG1848@2|Bacteria,4P4BC@976|Bacteroidetes	976|Bacteroidetes	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
WH2_k127_6066301_0	869213.JCM21142_41869	6.31e-63	219.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,47MYD@768503|Cytophagia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
WH2_k127_6101752_0	1313421.JHBV01000029_gene1879	5.019e-85	307.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,PKD,Peptidase_M43,SprB
WH2_k127_6101752_1	1408433.JHXV01000002_gene334	8.096e-49	196.0	COG2374@1|root,COG4935@1|root,COG2374@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,LTD,SLH
WH2_k127_6101752_2	1469557.JSWF01000036_gene808	2.069e-12	80.0	COG3209@1|root,COG3291@1|root,COG3897@1|root,COG4886@1|root,COG5306@1|root,COG5492@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3897@2|Bacteria,COG4886@2|Bacteria,COG5306@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	htaA	-	3.4.21.72	ko:K01347,ko:K03561,ko:K12287	-	-	-	-	ko00000,ko01000,ko01002,ko02000,ko02044	1.A.30.2.1,1.B.12.3	-	-	CHU_C,DUF2341,HtaA,LRR_5,Laminin_G_3,MotA_ExbB
WH2_k127_6101984_1	1123508.JH636439_gene1132	9.042e-46	173.0	COG1520@1|root,COG2373@1|root,COG2931@1|root,COG3386@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2J4W7@203682|Planctomycetes	2|Bacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,CHU_C,DUF11,DUF4347,SdrD_B
WH2_k127_6101984_0	1453500.AT05_00890	2.489e-130	424.0	COG0667@1|root,COG0667@2|Bacteria,4NFCN@976|Bacteroidetes,1HWKD@117743|Flavobacteriia	976|Bacteroidetes	C	PFAM aldo keto reductase	gpr	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
WH2_k127_6101984_2	926549.KI421517_gene1328	3.695e-15	76.0	COG0745@1|root,COG0745@2|Bacteria,4NE77@976|Bacteroidetes,47K3Z@768503|Cytophagia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WH2_k127_6117772_2	1123508.JH636439_gene1132	1.894e-09	69.0	COG1520@1|root,COG2373@1|root,COG2931@1|root,COG3386@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2J4W7@203682|Planctomycetes	2|Bacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,CHU_C,DUF11,DUF4347,SdrD_B
WH2_k127_6117772_1	313596.RB2501_15794	9.861e-33	145.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1HYIP@117743|Flavobacteriia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6117772_0	1408433.JHXV01000016_gene1822	9.387e-85	293.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia,2PBB7@246874|Cryomorphaceae	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
WH2_k127_6127116_0	1121904.ARBP01000001_gene5937	4.702e-185	594.0	COG4774@1|root,COG4774@2|Bacteria,4PKNF@976|Bacteroidetes,47XXH@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
WH2_k127_6127116_2	1237149.C900_00069	1.726e-43	167.0	COG3279@1|root,COG3279@2|Bacteria,4NF8A@976|Bacteroidetes	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
WH2_k127_6127116_1	1122176.KB903565_gene3261	2.419e-46	180.0	COG3920@1|root,COG3920@2|Bacteria,4NINT@976|Bacteroidetes,1IT68@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,TPR_12
WH2_k127_6131313_0	1089550.ATTH01000001_gene2147	1.792e-116	387.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1FJ5I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Bacterial regulatory protein, Fis family	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WH2_k127_6179646_0	153721.MYP_2988	2.733e-131	447.0	COG3188@1|root,COG3291@1|root,COG3188@2|Bacteria,COG3291@2|Bacteria,4NHVA@976|Bacteroidetes,47MA8@768503|Cytophagia	976|Bacteroidetes	NU	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PA14
WH2_k127_6179854_1	1313301.AUGC01000008_gene444	6.964e-69	259.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4NF8H@976|Bacteroidetes	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,Inhibitor_I69,MAM,Peptidase_C10,Peptidase_M14,Peptidase_M43,Reprolysin_4,fn3
WH2_k127_6179854_2	1237149.C900_03020	9.59e-48	184.0	COG0500@1|root,COG2226@2|Bacteria,4NICK@976|Bacteroidetes	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WH2_k127_6179854_0	1218108.KB908294_gene2348	4.115e-84	284.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,1HX41@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WH2_k127_6179854_3	1453500.AT05_04545	1.363e-29	119.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1HWSN@117743|Flavobacteriia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WH2_k127_6203887_0	927658.AJUM01000034_gene86	1.093e-206	661.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,2FMFA@200643|Bacteroidia,3XJCK@558415|Marinilabiliaceae	976|Bacteroidetes	L	MutS domain II	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WH2_k127_6205381_3	755732.Fluta_0011	1.26e-16	82.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,1I34F@117743|Flavobacteriia,2PBX8@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
WH2_k127_6205381_4	1162668.LFE_1370	4.351e-06	57.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
WH2_k127_6205381_2	313598.MED152_04460	1.731e-33	139.0	COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,1I2YC@117743|Flavobacteriia,3VWFV@52959|Polaribacter	976|Bacteroidetes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
WH2_k127_6205381_1	518766.Rmar_2000	4.029e-45	171.0	COG0778@1|root,COG0778@2|Bacteria,4NKRC@976|Bacteroidetes,1FJBU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WH2_k127_6205381_0	517418.Ctha_2249	7.405e-123	404.0	COG3540@1|root,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
WH2_k127_6212245_0	709991.Odosp_2293	4.486e-20	103.0	COG0457@1|root,COG0457@2|Bacteria,4P45T@976|Bacteroidetes,2FYEG@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6212245_1	292563.Cyast_0386	1.543e-13	76.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	GUN4,Pkinase,TPR_1
WH2_k127_6220935_0	760192.Halhy_1552	3.227e-52	194.0	COG0500@1|root,COG0500@2|Bacteria,4PNE0@976|Bacteroidetes	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WH2_k127_6220935_1	761193.Runsl_5265	3.708e-39	155.0	COG2135@1|root,COG2135@2|Bacteria,4NI3T@976|Bacteroidetes,47XPZ@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the SOS response-associated peptidase family	yoqW	-	-	-	-	-	-	-	-	-	-	-	SRAP
WH2_k127_6220935_3	1268072.PSAB_01800	2.678e-05	52.0	2CH44@1|root,32S57@2|Bacteria,1VCKH@1239|Firmicutes,4HKXX@91061|Bacilli,26XPU@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6220935_2	926562.Oweho_0457	1.963e-05	47.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia,2PBN1@246874|Cryomorphaceae	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_12,TPR_8
WH2_k127_6230088_0	376686.Fjoh_1489	6.207e-111	362.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1HX18@117743|Flavobacteriia,2NSI7@237|Flavobacterium	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
WH2_k127_6230088_3	700598.Niako_3067	9.534e-23	107.0	COG3637@1|root,COG3637@2|Bacteria,4NRN4@976|Bacteroidetes,1ITPS@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6230088_1	760192.Halhy_6389	1.144e-108	360.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1IQ87@117747|Sphingobacteriia	976|Bacteroidetes	V	COG1131 ABC-type multidrug transport system ATPase component	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH2_k127_6230088_2	264731.PRU_0075	1.722e-30	123.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,2FNY9@200643|Bacteroidia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
WH2_k127_6279081_1	525257.HMPREF0204_14646	1.642e-32	146.0	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,4P2RH@976|Bacteroidetes,1IJJ1@117743|Flavobacteriia,3ZQFH@59732|Chryseobacterium	976|Bacteroidetes	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,fn3
WH2_k127_6279081_0	391598.FBBAL38_01495	1.061e-58	229.0	COG1345@1|root,COG1361@1|root,COG3291@1|root,COG4733@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4NGSK@976|Bacteroidetes,1HXWK@117743|Flavobacteriia	976|Bacteroidetes	N	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	LTD
WH2_k127_6279081_3	153721.MYP_4087	0.0002362	54.0	COG2755@1|root,COG3866@1|root,COG2755@2|Bacteria,COG3866@2|Bacteria,4P09P@976|Bacteroidetes,47XYK@768503|Cytophagia	976|Bacteroidetes	EG	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_3,Laminin_G_3,Lipase_GDSL_2,fn3
WH2_k127_6279081_2	1122179.KB890436_gene1412	4.402e-11	76.0	COG1361@1|root,COG3055@1|root,COG3291@1|root,COG5492@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,4NEAB@976|Bacteroidetes,1IWYC@117747|Sphingobacteriia	976|Bacteroidetes	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Collagen_bind_2,DUF5060
WH2_k127_6295924_1	742817.HMPREF9449_01243	3.513e-31	131.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,2FMK5@200643|Bacteroidia,22X3E@171551|Porphyromonadaceae	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
WH2_k127_6295924_0	1077285.AGDG01000031_gene3739	4.85e-33	139.0	COG0457@1|root,COG3103@1|root,COG0457@2|Bacteria,COG3103@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia,4AKSZ@815|Bacteroidaceae	976|Bacteroidetes	T	COG NOG22299 non supervised orthologous group	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
WH2_k127_6295924_2	929703.KE386491_gene4131	2.255e-17	88.0	2DBH5@1|root,2Z97Q@2|Bacteria,4NK7F@976|Bacteroidetes,47YKW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6316957_0	362418.IW19_19820	2.731e-36	149.0	COG2197@1|root,COG2197@2|Bacteria,4PI93@976|Bacteroidetes,1IG32@117743|Flavobacteriia,2NV3E@237|Flavobacterium	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH2_k127_6316957_1	1185876.BN8_05137	5.379e-24	113.0	COG4585@1|root,COG4585@2|Bacteria,4NNE1@976|Bacteroidetes,47PFT@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
WH2_k127_6320191_2	760568.Desku_1748	1.167e-72	250.0	COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,251A8@186801|Clostridia,264EF@186807|Peptococcaceae	186801|Clostridia	M	PFAM NAD dependent epimerase dehydratase family	capI	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
WH2_k127_6320191_1	1168289.AJKI01000012_gene311	4.603e-92	313.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.348	ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WH2_k127_6320191_3	929703.KE386491_gene2468	3.54e-34	143.0	COG2755@1|root,COG2755@2|Bacteria,4NRGK@976|Bacteroidetes,47W4S@768503|Cytophagia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6320191_0	391587.KAOT1_18802	3.717e-177	572.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia	976|Bacteroidetes	M	Membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
WH2_k127_6320191_5	78245.Xaut_4480	2.95e-07	61.0	COG4675@1|root,COG4675@2|Bacteria,1PE25@1224|Proteobacteria,2V8UM@28211|Alphaproteobacteria,3F1UP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6320191_6	323097.Nham_2380	2.707e-05	55.0	COG5301@1|root,COG5301@2|Bacteria,1QWSJ@1224|Proteobacteria,2TX42@28211|Alphaproteobacteria,3K6RM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	cellulose 1,4-beta-cellobiosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6320191_4	290318.Cvib_0424	2.198e-07	59.0	COG0823@1|root,COG2911@1|root,COG2931@1|root,COG2982@1|root,COG3210@1|root,COG4932@1|root,COG5276@1|root,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG2982@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	M	domain protein	-	-	3.2.1.65	ko:K01212,ko:K12287,ko:K20276	ko00500,ko02024,map00500,map02024	-	R05624,R11311	RC03278	ko00000,ko00001,ko01000,ko02044	-	GH32	-	DUF4347
WH2_k127_6324324_1	1408433.JHXV01000010_gene542	4.011e-78	276.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,1IJJS@117743|Flavobacteriia,2PAXM@246874|Cryomorphaceae	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
WH2_k127_6324324_3	1408473.JHXO01000010_gene3597	5.791e-63	228.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,2FMGW@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WH2_k127_6324324_2	1453500.AT05_00255	6.133e-68	241.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,1HX94@117743|Flavobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
WH2_k127_6324324_0	714943.Mucpa_4396	5.741e-178	578.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,1IPN2@117747|Sphingobacteriia	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
WH2_k127_6331643_0	1408433.JHXV01000002_gene442	5.772e-85	296.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
WH2_k127_6338967_1	626522.GCWU000325_01810	3.286e-21	95.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,2FKZ9@200643|Bacteroidia,1WD38@1283313|Alloprevotella	976|Bacteroidetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WH2_k127_6338967_0	926562.Oweho_0720	4.699e-56	223.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWKQ@117743|Flavobacteriia,2PA5P@246874|Cryomorphaceae	976|Bacteroidetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	-	-	-	-	-	-	-	-	-	TamB
WH2_k127_6372630_0	1408473.JHXO01000001_gene2471	3.538e-91	326.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia	976|Bacteroidetes	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
WH2_k127_6372630_1	926562.Oweho_0085	2.678e-75	260.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,1HWV0@117743|Flavobacteriia,2PA4U@246874|Cryomorphaceae	976|Bacteroidetes	S	Transporter associated domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
WH2_k127_6372950_2	1150600.ADIARSV_3941	6.096e-18	84.0	COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes,1IR1U@117747|Sphingobacteriia	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
WH2_k127_6372950_1	313606.M23134_07226	2.555e-40	168.0	COG2324@1|root,COG2324@2|Bacteria,4NQR7@976|Bacteroidetes,47QH8@768503|Cytophagia	976|Bacteroidetes	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
WH2_k127_6372950_0	1048983.EL17_11325	2.798e-72	263.0	arCOG05416@1|root,2ZZTD@2|Bacteria,4NNMY@976|Bacteroidetes,47Q57@768503|Cytophagia	976|Bacteroidetes	S	lycopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_637996_1	1121012.AUKX01000023_gene1801	1.528e-34	144.0	COG3278@1|root,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1HWK8@117743|Flavobacteriia,23HRW@178469|Arenibacter	976|Bacteroidetes	O	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
WH2_k127_637996_0	866536.Belba_3227	7.607e-45	167.0	COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,47V3J@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
WH2_k127_637996_2	1121957.ATVL01000014_gene1459	2.515e-06	53.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6398923_2	1122978.AUFP01000009_gene62	6.841e-10	62.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,2FMY5@200643|Bacteroidia	976|Bacteroidetes	S	ABC transporter, ATP-binding protein	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WH2_k127_6398923_0	1408433.JHXV01000024_gene1509	1.898e-70	252.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,1HX8Y@117743|Flavobacteriia,2PAWJ@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM gliding motility associated protien GldN	gldN	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6398923_1	927658.AJUM01000034_gene422	3.465e-57	211.0	28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,2FNU8@200643|Bacteroidia,3XIKX@558415|Marinilabiliaceae	976|Bacteroidetes	S	GldM C-terminal domain	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
WH2_k127_6403464_0	742725.HMPREF9450_00464	2.977e-115	385.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,2FMFI@200643|Bacteroidia,22U0G@171550|Rikenellaceae	976|Bacteroidetes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
WH2_k127_6403464_1	760192.Halhy_0377	1.378e-50	189.0	COG2227@1|root,COG2227@2|Bacteria,4PNUQ@976|Bacteroidetes,1IYVG@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WH2_k127_6403464_2	760192.Halhy_0377	1.195e-48	184.0	COG2227@1|root,COG2227@2|Bacteria,4PNUQ@976|Bacteroidetes,1IYVG@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WH2_k127_64241_2	1116472.MGMO_15c00470	7.24e-23	102.0	COG4634@1|root,COG4634@2|Bacteria,1PSZD@1224|Proteobacteria,1SUWV@1236|Gammaproteobacteria,1XGR8@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_64241_1	1189612.A33Q_0026	5.988e-31	132.0	2CE7Q@1|root,32RZA@2|Bacteria,4NSYK@976|Bacteroidetes,47R4R@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_64241_0	1124780.ANNU01000059_gene878	8.074e-70	243.0	COG0009@1|root,COG0009@2|Bacteria,4NF5U@976|Bacteroidetes,47KX9@768503|Cytophagia	976|Bacteroidetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua5	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
WH2_k127_6427108_2	1122179.KB890436_gene1412	9.451e-05	55.0	COG1361@1|root,COG3055@1|root,COG3291@1|root,COG5492@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,4NEAB@976|Bacteroidetes,1IWYC@117747|Sphingobacteriia	976|Bacteroidetes	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Collagen_bind_2,DUF5060
WH2_k127_6427108_1	927658.AJUM01000037_gene2301	1.785e-25	121.0	COG3291@1|root,COG3291@2|Bacteria,4P5RR@976|Bacteroidetes,2G25G@200643|Bacteroidia,3XJXF@558415|Marinilabiliaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
WH2_k127_6427108_0	888059.HMPREF9071_1957	9.325e-45	172.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HWKC@117743|Flavobacteriia,1ERCC@1016|Capnocytophaga	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
WH2_k127_6431381_0	926562.Oweho_2781	1.041e-151	494.0	COG0845@1|root,COG0845@2|Bacteria,4NFEK@976|Bacteroidetes,1HXDY@117743|Flavobacteriia,2PBC9@246874|Cryomorphaceae	976|Bacteroidetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
WH2_k127_6432538_0	1408433.JHXV01000010_gene620	3.929e-98	332.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1HYK6@117743|Flavobacteriia,2PA4T@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
WH2_k127_6432538_1	1443665.JACA01000013_gene4207	1.424e-74	278.0	COG0265@1|root,COG0265@2|Bacteria,4PKT1@976|Bacteroidetes,1I89F@117743|Flavobacteriia,2YGTW@290174|Aquimarina	976|Bacteroidetes	O	Trypsin-like peptidase domain	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2,fn3
WH2_k127_6432538_3	870187.Thini_2163	3.732e-35	155.0	COG0823@1|root,COG2834@1|root,COG0823@2|Bacteria,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4214,Fn3_assoc,LRR_5,REJ,SLH,fn3
WH2_k127_6432538_2	1304872.JAGC01000009_gene545	2.382e-70	246.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria,2M920@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
WH2_k127_6433337_0	1313421.JHBV01000036_gene2482	3.898e-137	448.0	COG4867@1|root,COG4867@2|Bacteria,4NFMA@976|Bacteroidetes,1INMN@117747|Sphingobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
WH2_k127_6433337_1	1121957.ATVL01000007_gene1691	5.996e-120	391.0	COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,47JD2@768503|Cytophagia	976|Bacteroidetes	H	magnesium chelatase	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Sigma54_activat
WH2_k127_6436770_1	755732.Fluta_0751	4.065e-138	452.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,1HXZ3@117743|Flavobacteriia,2PAK9@246874|Cryomorphaceae	976|Bacteroidetes	F	PFAM Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
WH2_k127_6436770_0	755732.Fluta_0750	3.284e-198	625.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,1HWRR@117743|Flavobacteriia,2PAAC@246874|Cryomorphaceae	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
WH2_k127_6436770_2	762903.Pedsa_1239	1.581e-86	295.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1IP3C@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WH2_k127_6438619_3	929713.NIASO_00205	5.862e-48	174.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,1IQ61@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	tdh	-	-	-	-	-	-	-	-	-	-	-	Epimerase
WH2_k127_6438619_4	1408433.JHXV01000014_gene3691	5.314e-37	151.0	COG2849@1|root,COG2849@2|Bacteria,4PG65@976|Bacteroidetes,1IMR5@117743|Flavobacteriia,2PBMX@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
WH2_k127_6438619_0	1123008.KB905696_gene2890	1.993e-209	663.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,2FM9D@200643|Bacteroidia,22WDE@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
WH2_k127_6438619_1	869213.JCM21142_303	1.27e-92	317.0	COG2234@1|root,COG2234@2|Bacteria,4NG2A@976|Bacteroidetes,47KMC@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M28	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WH2_k127_6438619_2	216432.CA2559_00200	4.889e-90	306.0	COG3291@1|root,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes,1IJEU@117743|Flavobacteriia	976|Bacteroidetes	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,MAM,UnbV_ASPIC,VCBS,fn3
WH2_k127_6440520_1	194439.CT0091	1.314e-36	144.0	COG2062@1|root,COG2062@2|Bacteria,1FE6K@1090|Chlorobi	1090|Chlorobi	T	PFAM Phosphoglycerate mutase	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
WH2_k127_6440520_2	1270193.JARP01000004_gene1331	7.186e-27	122.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I23H@117743|Flavobacteriia,2P06D@237|Flavobacterium	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
WH2_k127_6440520_0	616991.JPOO01000001_gene4614	1.789e-49	178.0	2AY99@1|root,31QBJ@2|Bacteria,4NNSA@976|Bacteroidetes,1I2AG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
WH2_k127_6440520_3	643867.Ftrac_2073	4.005e-18	86.0	COG1327@1|root,COG1327@2|Bacteria,4NHXI@976|Bacteroidetes,47P1Y@768503|Cytophagia	976|Bacteroidetes	K	PFAM ATP cone domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-cone,Mrr_cat
WH2_k127_6440560_8	926562.Oweho_1648	1.597e-11	66.0	2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,1I425@117743|Flavobacteriia,2PB6J@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4286)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4286
WH2_k127_6440560_3	471854.Dfer_5760	2.202e-78	273.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,47KWT@768503|Cytophagia	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
WH2_k127_6440560_0	927658.AJUM01000037_gene2090	4.773e-126	418.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,2FN1M@200643|Bacteroidia,3XIN2@558415|Marinilabiliaceae	976|Bacteroidetes	P	MgtE intracellular N domain	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
WH2_k127_6440560_4	755732.Fluta_1420	1.216e-72	269.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1HXGX@117743|Flavobacteriia,2PAGW@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WH2_k127_6440560_5	309807.SRU_0571	1.411e-68	244.0	COG0584@1|root,COG0584@2|Bacteria,4NGI1@976|Bacteroidetes,1FJ5D@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,Phytase-like
WH2_k127_6440560_1	1408433.JHXV01000040_gene1539	1.447e-122	406.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1HWT8@117743|Flavobacteriia,2PAIM@246874|Cryomorphaceae	976|Bacteroidetes	E	Amino acid kinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
WH2_k127_6440560_6	1454007.JAUG01000010_gene2514	3.06e-40	153.0	2AFHA@1|root,315HT@2|Bacteria,4NQ5F@976|Bacteroidetes,1IYIE@117747|Sphingobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WH2_k127_6440560_2	290315.Clim_0222	3.723e-85	294.0	COG3039@1|root,COG3039@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
WH2_k127_6440560_7	1121957.ATVL01000010_gene395	1.698e-18	87.0	COG0454@1|root,COG0456@2|Bacteria,4NNJS@976|Bacteroidetes,47PUS@768503|Cytophagia	976|Bacteroidetes	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WH2_k127_6457731_1	1121859.KB890739_gene2666	9.407e-102	344.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,47KF9@768503|Cytophagia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
WH2_k127_6457731_2	755732.Fluta_1004	1.248e-44	168.0	COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,1I202@117743|Flavobacteriia,2PAYJ@246874|Cryomorphaceae	976|Bacteroidetes	J	Ribosomal protein L9, C-terminal domain	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
WH2_k127_6457731_3	1380384.JADN01000007_gene1634	1.852e-41	153.0	COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,1I2TD@117743|Flavobacteriia	976|Bacteroidetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
WH2_k127_6457731_4	1168034.FH5T_18225	1.985e-40	155.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,2FSHK@200643|Bacteroidia	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
WH2_k127_6457731_0	525373.HMPREF0766_11006	7.117e-150	486.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1IQ35@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
WH2_k127_6463365_1	880073.Calab_0998	8.366e-54	190.0	COG1506@1|root,COG1506@2|Bacteria,2NQR2@2323|unclassified Bacteria	2|Bacteria	E	Alpha/beta hydrolase family	ptpA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
WH2_k127_6463365_0	1122176.KB903532_gene2565	5.38e-68	242.0	COG5337@1|root,COG5337@2|Bacteria,4NEH2@976|Bacteroidetes	976|Bacteroidetes	M	sodium ion export across plasma membrane	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
WH2_k127_6474590_0	1408433.JHXV01000025_gene4054	4.228e-30	138.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,1HYTK@117743|Flavobacteriia,2PB8R@246874|Cryomorphaceae	976|Bacteroidetes	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,TSP_3
WH2_k127_6476839_0	459349.CLOAM0192	1.525e-71	261.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	Autotransporter,FlgD_ig,PKD
WH2_k127_6476839_1	1122176.KB903587_gene4515	3.818e-19	102.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF5011,HYR,Laminin_G_3,SprB
WH2_k127_6480263_1	313596.RB2501_15184	1.661e-87	295.0	COG1044@1|root,COG1044@2|Bacteria,4NFXA@976|Bacteroidetes,1HXWG@117743|Flavobacteriia	976|Bacteroidetes	M	glucosamine N-acyltransferase	lpxD1	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
WH2_k127_6480263_2	1408433.JHXV01000009_gene1349	5.766e-81	294.0	COG2208@1|root,COG2208@2|Bacteria,4NI98@976|Bacteroidetes,1IMQG@117743|Flavobacteriia,2PBAV@246874|Cryomorphaceae	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
WH2_k127_6480263_0	1408433.JHXV01000009_gene1254	1.762e-122	408.0	COG3307@1|root,COG3307@2|Bacteria,4NMYT@976|Bacteroidetes,1I79G@117743|Flavobacteriia,2PAI6@246874|Cryomorphaceae	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WH2_k127_6480263_3	1168034.FH5T_03520	6.123e-27	119.0	COG3206@1|root,COG3206@2|Bacteria,4NSFM@976|Bacteroidetes	976|Bacteroidetes	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6485025_1	929556.Solca_0293	3.182e-72	259.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1IRAV@117747|Sphingobacteriia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6485025_3	240016.ABIZ01000001_gene1081	2.09e-12	77.0	COG1434@1|root,COG1434@2|Bacteria	2|Bacteria	S	Gram-negative-bacterium-type cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
WH2_k127_6485025_0	1313421.JHBV01000043_gene3095	1.478e-127	437.0	COG0265@1|root,COG0265@2|Bacteria,4PKT1@976|Bacteroidetes	976|Bacteroidetes	O	COG3209 Rhs family protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
WH2_k127_6485025_2	1443665.JACA01000013_gene4207	8.097e-39	153.0	COG0265@1|root,COG0265@2|Bacteria,4PKT1@976|Bacteroidetes,1I89F@117743|Flavobacteriia,2YGTW@290174|Aquimarina	976|Bacteroidetes	O	Trypsin-like peptidase domain	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2,fn3
WH2_k127_6490476_1	742725.HMPREF9450_01186	6.009e-65	224.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,2FM9P@200643|Bacteroidia,22U7E@171550|Rikenellaceae	976|Bacteroidetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
WH2_k127_6490476_0	1408433.JHXV01000024_gene1451	5.349e-75	259.0	COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,1I2CE@117743|Flavobacteriia,2PBPQ@246874|Cryomorphaceae	976|Bacteroidetes	GM	COG4464 Capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
WH2_k127_6495493_1	667015.Bacsa_1944	1.964e-21	99.0	COG1569@1|root,COG1569@2|Bacteria,4NSFI@976|Bacteroidetes,2FSDV@200643|Bacteroidia,4AQMM@815|Bacteroidaceae	976|Bacteroidetes	S	Toxin-antitoxin system, toxin component, PIN family	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
WH2_k127_6495493_0	1307761.L21SP2_3313	9.186e-32	138.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
WH2_k127_6495493_2	869213.JCM21142_93524	5.115e-14	79.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6499480_2	714943.Mucpa_0105	1.53e-15	87.0	COG2885@1|root,COG2885@2|Bacteria,4NYQV@976|Bacteroidetes	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6499480_0	485918.Cpin_6574	2.287e-113	377.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,1IQP9@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
WH2_k127_6499480_1	1408473.JHXO01000016_gene1927	6.328e-60	221.0	COG1506@1|root,COG1506@2|Bacteria,4NF7I@976|Bacteroidetes,2FMJD@200643|Bacteroidia	976|Bacteroidetes	E	Peptidase, S9A B C family, catalytic domain protein	ptpA	-	3.4.14.12,3.4.14.5	ko:K01278,ko:K18574	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
WH2_k127_6506191_1	926562.Oweho_1915	3.91e-14	83.0	COG3291@1|root,COG3291@2|Bacteria,4P5U5@976|Bacteroidetes,1IAAB@117743|Flavobacteriia,2PB83@246874|Cryomorphaceae	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6506191_2	1122179.KB890422_gene2240	9.406e-14	85.0	COG2931@1|root,COG3227@1|root,COG3292@1|root,COG2931@2|Bacteria,COG3227@2|Bacteria,COG3292@2|Bacteria,4NHTI@976|Bacteroidetes	976|Bacteroidetes	T	zinc metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	CUB,Pep_M12B_propep,Reprolysin_5
WH2_k127_6506191_0	1453500.AT05_05380	2.087e-38	164.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	4.2.2.1	ko:K01727	-	-	-	-	ko00000,ko01000	-	PL8	-	Alginate_lyase,BNR_2,Exo_endo_phos,F5_F8_type_C,Laminin_G_3,Metallophos,PA14,SASA,SLH
WH2_k127_6527254_0	1380346.JNIH01000016_gene493	1.686e-12	80.0	COG1470@1|root,COG3055@1|root,COG4934@1|root,COG1470@2|Bacteria,COG3055@2|Bacteria,COG4934@2|Bacteria,2IF2T@201174|Actinobacteria	201174|Actinobacteria	O	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Kelch_1
WH2_k127_6527254_1	755732.Fluta_1673	9.194e-07	55.0	COG2911@1|root,COG3266@1|root,COG2911@2|Bacteria,COG3266@2|Bacteria,4PKFD@976|Bacteroidetes,1IKC5@117743|Flavobacteriia	976|Bacteroidetes	S	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
WH2_k127_6527404_3	929556.Solca_4457	3.029e-10	70.0	2EM8X@1|root,33EY2@2|Bacteria,4NYIN@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4412
WH2_k127_6527404_2	926549.KI421517_gene1736	5.197e-20	99.0	COG2755@1|root,COG2755@2|Bacteria,4NPB3@976|Bacteroidetes,47RNJ@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
WH2_k127_6527404_1	929703.KE386491_gene245	1.426e-55	209.0	2A5IV@1|root,30U93@2|Bacteria,4NNIA@976|Bacteroidetes,47RFH@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6527404_0	755732.Fluta_0187	1.8e-158	508.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia,2PBCE@246874|Cryomorphaceae	976|Bacteroidetes	M	membrane protein involved in D-alanine export	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
WH2_k127_6530301_0	755732.Fluta_0839	1.043e-131	426.0	COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,1HWQC@117743|Flavobacteriia,2PADS@246874|Cryomorphaceae	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
WH2_k127_6530301_2	1408433.JHXV01000015_gene1752	2.86e-89	302.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,1HX74@117743|Flavobacteriia,2PAQ1@246874|Cryomorphaceae	976|Bacteroidetes	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
WH2_k127_6530301_1	1408433.JHXV01000015_gene1753	6.559e-105	349.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1HX9P@117743|Flavobacteriia,2PAQ3@246874|Cryomorphaceae	976|Bacteroidetes	C	Electron transfer flavoprotein domain	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
WH2_k127_6530301_3	1408433.JHXV01000015_gene1754	3.717e-38	146.0	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,1HXCB@117743|Flavobacteriia,2PAS5@246874|Cryomorphaceae	976|Bacteroidetes	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
WH2_k127_6549682_0	926562.Oweho_3351	1.239e-139	466.0	28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,1I791@117743|Flavobacteriia,2PA5S@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6556841_0	1469557.JSWF01000020_gene134	3.709e-37	159.0	COG4932@1|root,COG4932@2|Bacteria,4PN87@976|Bacteroidetes	976|Bacteroidetes	M	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11
WH2_k127_6556841_1	134676.ACPL_614	1.604e-25	123.0	COG1520@1|root,COG1520@2|Bacteria,2I2T4@201174|Actinobacteria,4D8TV@85008|Micromonosporales	201174|Actinobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2
WH2_k127_6557152_0	1168034.FH5T_07250	2.4e-99	335.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,2G2RU@200643|Bacteroidia	976|Bacteroidetes	E	Peptidase family M1 domain	pepN1	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
WH2_k127_6557152_2	1250278.JQNQ01000001_gene1920	1.443e-68	250.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,1HYXC@117743|Flavobacteriia	976|Bacteroidetes	H	Riboflavin synthase	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
WH2_k127_6557152_1	1408433.JHXV01000014_gene3628	7.64e-75	259.0	COG3291@1|root,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes,1I840@117743|Flavobacteriia,2PBAC@246874|Cryomorphaceae	976|Bacteroidetes	Q	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
WH2_k127_6563857_0	1123276.KB893301_gene4272	4.548e-22	110.0	2DBRU@1|root,2ZANA@2|Bacteria,4NF9E@976|Bacteroidetes,47NCU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6563857_1	714943.Mucpa_6633	5.953e-12	66.0	COG0463@1|root,COG0463@2|Bacteria,4NEVT@976|Bacteroidetes,1IPAW@117747|Sphingobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	arnC	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH2_k127_6568584_1	1223410.KN050846_gene869	1.003e-32	134.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,1HXM8@117743|Flavobacteriia	976|Bacteroidetes	C	NADH dehydrogenase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WH2_k127_6568584_0	649349.Lbys_1850	9.369e-119	396.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,47JRR@768503|Cytophagia	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
WH2_k127_6584236_0	1408433.JHXV01000015_gene1745	1.192e-67	241.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Antigen_C,DUF4150,PorP_SprF
WH2_k127_6584236_1	1313421.JHBV01000039_gene2730	9.186e-50	192.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
WH2_k127_6589255_1	1122176.KB903532_gene2557	5.592e-14	73.0	COG1418@1|root,COG1418@2|Bacteria,4NFAG@976|Bacteroidetes,1ISTR@117747|Sphingobacteriia	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HD
WH2_k127_6589255_2	1385935.N836_35430	1.685e-11	70.0	2EPF5@1|root,33H1T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6589255_0	1123389.ATXJ01000001_gene663	1.989e-35	147.0	COG1266@1|root,COG1266@2|Bacteria,1WIPS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WH2_k127_6597056_0	755732.Fluta_3714	3e-320	1000.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
WH2_k127_6619324_0	760192.Halhy_0634	2.911e-53	204.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1IW1C@117747|Sphingobacteriia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
WH2_k127_6627371_1	379066.GAU_3018	6.264e-74	258.0	COG0349@1|root,COG0349@2|Bacteria,1ZSPS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
WH2_k127_6627371_2	391037.Sare_1667	1.692e-10	66.0	COG0640@1|root,COG0640@2|Bacteria,2IKUI@201174|Actinobacteria,4DGPM@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
WH2_k127_6627371_0	1034807.FBFL15_1135	8.882e-96	320.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,1HWSW@117743|Flavobacteriia,2NSXA@237|Flavobacterium	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WH2_k127_6627593_1	521097.Coch_1402	2.969e-29	122.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,1I47M@117743|Flavobacteriia,1ES0F@1016|Capnocytophaga	976|Bacteroidetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
WH2_k127_6627593_2	1461577.CCMH01000006_gene2010	8.367e-06	57.0	2EFZ5@1|root,339RB@2|Bacteria,4NXH9@976|Bacteroidetes	976|Bacteroidetes	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
WH2_k127_6627593_0	391596.PBAL39_09461	2.014e-104	352.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1IPTF@117747|Sphingobacteriia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
WH2_k127_6627593_3	1124780.ANNU01000006_gene2926	0.0008741	42.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,47S5V@768503|Cytophagia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
WH2_k127_662833_1	1033991.RLEG12_13500	2.103e-54	199.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,2TU3M@28211|Alphaproteobacteria,4BBEB@82115|Rhizobiaceae	28211|Alphaproteobacteria	GM	ATP-binding protein	wzt	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
WH2_k127_662833_2	700598.Niako_3020	2.807e-39	170.0	COG1216@1|root,COG1216@2|Bacteria,4NKMR@976|Bacteroidetes,1IZ0H@117747|Sphingobacteriia	976|Bacteroidetes	S	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
WH2_k127_662833_0	118168.MC7420_3577	3.094e-107	385.0	COG1215@1|root,COG1216@1|root,COG2227@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,COG2227@2|Bacteria,1GQBE@1117|Cyanobacteria,1H7DT@1150|Oscillatoriales	1117|Cyanobacteria	M	glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,RgpF,TPR_1,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8
WH2_k127_6633416_0	167548.EU98_1805	8.516e-64	246.0	28JA7@1|root,2Z951@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CotH
WH2_k127_6633416_1	1121939.L861_11985	0.0001518	55.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,1XJ9U@135619|Oceanospirillales	135619|Oceanospirillales	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
WH2_k127_6639218_0	1245469.S58_58540	1.322e-82	276.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2TSH1@28211|Alphaproteobacteria,3JR0F@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hupL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
WH2_k127_6639218_1	1232683.ADIMK_0116	2.391e-71	248.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,1RNTH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	b-type cytochrome subunit	hyaC	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
WH2_k127_6639218_3	62928.azo3789	1.49e-23	104.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,2VU0Y@28216|Betaproteobacteria,2KXJ6@206389|Rhodocyclales	206389|Rhodocyclales	K	Helix-turn-helix	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
WH2_k127_6639218_2	290397.Adeh_2791	1.683e-36	139.0	COG0493@1|root,COG0543@1|root,COG1633@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,COG1633@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WKB4@28221|Deltaproteobacteria,2YTUD@29|Myxococcales	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
WH2_k127_6673922_2	1408433.JHXV01000015_gene1740	7.696e-16	82.0	2DGVM@1|root,2ZXFN@2|Bacteria,4P8FH@976|Bacteroidetes,1IMT9@117743|Flavobacteriia,2PC3X@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6673922_4	1250005.PHEL85_0653	1.021e-07	63.0	2E6TM@1|root,331DG@2|Bacteria,4NYW8@976|Bacteroidetes,1I8QW@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
WH2_k127_6673922_1	926562.Oweho_2644	6.087e-66	233.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1HXP2@117743|Flavobacteriia,2PAWG@246874|Cryomorphaceae	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
WH2_k127_6673922_0	1121373.KB903663_gene1207	1.843e-89	305.0	COG5285@1|root,COG5285@2|Bacteria,4NMHK@976|Bacteroidetes,47RPD@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
WH2_k127_6673922_3	1121904.ARBP01000002_gene6918	2.401e-14	73.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,47UE3@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter C-terminal domain	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WH2_k127_670344_2	1408433.JHXV01000029_gene3072	4.089e-45	168.0	COG2067@1|root,COG2067@2|Bacteria,4NE43@976|Bacteroidetes,1HZ3R@117743|Flavobacteriia,2PA70@246874|Cryomorphaceae	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_670344_3	313606.M23134_03729	7.212e-43	168.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,47PCF@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
WH2_k127_670344_4	1408433.JHXV01000029_gene3070	1.57e-26	111.0	COG1828@1|root,COG1828@2|Bacteria,4NV1M@976|Bacteroidetes,1IB4Z@117743|Flavobacteriia,2PBZ3@246874|Cryomorphaceae	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine (FGAM) synthase	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
WH2_k127_670344_1	1406840.Q763_00740	3.243e-113	375.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1HX61@117743|Flavobacteriia,2NU9K@237|Flavobacterium	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
WH2_k127_670344_0	153721.MYP_191	1.829e-175	573.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,47MWA@768503|Cytophagia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
WH2_k127_673149_0	929562.Emtol_2655	2.357e-93	321.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,47MT9@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WH2_k127_673149_1	269798.CHU_2808	4.621e-85	297.0	COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes,47KRY@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WH2_k127_6735340_0	1453500.AT05_00800	3.652e-84	285.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,1HWPS@117743|Flavobacteriia	976|Bacteroidetes	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
WH2_k127_6735340_2	1239962.C943_02146	6.069e-37	144.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,47RF4@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WH2_k127_6735340_1	1279009.ADICEAN_01440	3.975e-71	249.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,47MAV@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
WH2_k127_6736305_0	1408433.JHXV01000007_gene2926	8.654e-126	423.0	COG1629@1|root,COG4771@2|Bacteria,4NET0@976|Bacteroidetes,1HY46@117743|Flavobacteriia,2PAD5@246874|Cryomorphaceae	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
WH2_k127_6738239_0	1123248.KB893331_gene3789	3.61e-78	268.0	COG4242@1|root,COG4242@2|Bacteria,4NI55@976|Bacteroidetes,1IREV@117747|Sphingobacteriia	976|Bacteroidetes	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
WH2_k127_6738239_1	1384054.N790_09330	5.827e-39	151.0	2CHCP@1|root,32S5R@2|Bacteria,1MZ97@1224|Proteobacteria,1S8M3@1236|Gammaproteobacteria,1XAU1@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WH2_k127_6738239_2	388413.ALPR1_10810	2.397e-23	102.0	COG0477@1|root,COG2814@2|Bacteria,4NUYS@976|Bacteroidetes,47S3H@768503|Cytophagia	976|Bacteroidetes	EGP	Domain of unknown function (DUF3817)	ydzA	-	-	-	-	-	-	-	-	-	-	-	DUF3817
WH2_k127_6738239_3	546275.FUSPEROL_00900	7.388e-05	50.0	COG4980@1|root,COG4980@2|Bacteria,37ABY@32066|Fusobacteria	32066|Fusobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
WH2_k127_6742641_0	927658.AJUM01000047_gene2840	2.408e-46	173.0	COG3271@1|root,COG3271@2|Bacteria,4NN8E@976|Bacteroidetes,2G23E@200643|Bacteroidia,3XJE1@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
WH2_k127_6742641_1	1408473.JHXO01000016_gene1935	3.628e-21	105.0	2D6WA@1|root,32TMZ@2|Bacteria,4NU16@976|Bacteroidetes,2FYYU@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
WH2_k127_6742641_2	1408473.JHXO01000016_gene1934	2.419e-12	68.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,2FR8P@200643|Bacteroidia	976|Bacteroidetes	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
WH2_k127_675185_0	313606.M23134_02426	6.735e-70	256.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,47MIN@768503|Cytophagia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
WH2_k127_675185_1	1313301.AUGC01000001_gene1682	3.099e-58	215.0	COG0265@1|root,COG1073@1|root,COG0265@2|Bacteria,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	2.7.11.1,3.4.21.107	ko:K04771,ko:K06889,ko:K07090,ko:K14949	ko01503,ko02020,ko05152,map01503,map02020,map05152	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01002,ko03110	-	-	-	Hydrolase_4,PDZ_2,Trypsin_2
WH2_k127_6753619_2	1121129.KB903371_gene257	1.966e-09	58.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,2FME3@200643|Bacteroidia,22X07@171551|Porphyromonadaceae	976|Bacteroidetes	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WH2_k127_6753619_1	886379.AEWI01000046_gene3105	6.295e-29	121.0	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,2FTI6@200643|Bacteroidia,3XK3K@558415|Marinilabiliaceae	976|Bacteroidetes	K	helix_turn_helix, mercury resistance	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
WH2_k127_6753619_0	761193.Runsl_3470	6.981e-144	462.0	COG0451@1|root,COG0451@2|Bacteria,4NIZG@976|Bacteroidetes,47KEK@768503|Cytophagia	976|Bacteroidetes	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
WH2_k127_6771877_0	1380370.JIBA01000012_gene3413	6.643e-97	326.0	COG1501@1|root,COG1501@2|Bacteria,2GP4V@201174|Actinobacteria,4FG4A@85021|Intrasporangiaceae	201174|Actinobacteria	G	Glycosyl hydrolases family 31	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
WH2_k127_6771877_1	468059.AUHA01000005_gene2438	1.551e-92	321.0	COG3203@1|root,COG3203@2|Bacteria,4PMSP@976|Bacteroidetes	976|Bacteroidetes	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
WH2_k127_6771877_3	1123234.AUKI01000011_gene1294	9.563e-24	104.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,1I4FW@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WH2_k127_6771877_2	1120965.AUBV01000001_gene3366	1.173e-34	141.0	COG3118@1|root,COG3118@2|Bacteria,4NS6N@976|Bacteroidetes,47R18@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WH2_k127_6778068_3	926562.Oweho_0716	5.507e-32	128.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1HXJ6@117743|Flavobacteriia,2PAN4@246874|Cryomorphaceae	976|Bacteroidetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
WH2_k127_6778068_2	1408433.JHXV01000038_gene2219	1.142e-100	343.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,1IEBF@117743|Flavobacteriia,2PB0Z@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
WH2_k127_6778068_1	1121957.ATVL01000007_gene1748	5.479e-108	368.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,47KVT@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
WH2_k127_6778068_0	1122621.ATZA01000068_gene442	2.364e-138	446.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,1INQM@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
WH2_k127_6784042_1	760192.Halhy_0914	4.602e-05	56.0	2EKHJ@1|root,33E7I@2|Bacteria,4P6IY@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6784042_0	616991.JPOO01000003_gene989	3.527e-48	179.0	COG3503@1|root,COG3503@2|Bacteria,4NFAF@976|Bacteroidetes,1HX24@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
WH2_k127_6785691_0	1107311.Q767_11250	2.001e-148	483.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,1HZPF@117743|Flavobacteriia,2NTIK@237|Flavobacterium	976|Bacteroidetes	S	Spore maturation protein	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
WH2_k127_6785691_1	935863.AWZR01000007_gene343	6.84e-71	243.0	COG2940@1|root,COG2940@2|Bacteria,1MWFB@1224|Proteobacteria,1SAJ4@1236|Gammaproteobacteria,1X5YA@135614|Xanthomonadales	135614|Xanthomonadales	S	SET domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
WH2_k127_6785691_3	1121373.KB903664_gene2621	2.466e-33	140.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,47PRT@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
WH2_k127_6785691_4	287986.DV20_14170	1.03e-28	130.0	COG1765@1|root,COG1765@2|Bacteria,2IIKU@201174|Actinobacteria,4E3BN@85010|Pseudonocardiales	201174|Actinobacteria	O	OsmC-like protein	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
WH2_k127_6785691_2	1123400.KB904776_gene2011	6.368e-42	162.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,1RCN9@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,Ferritin-like,zf-CDGSH
WH2_k127_6785691_5	997346.HMPREF9374_3963	1.41e-24	108.0	COG2162@1|root,COG2162@2|Bacteria,1V2RN@1239|Firmicutes,4HG63@91061|Bacilli,27CY2@186824|Thermoactinomycetaceae	91061|Bacilli	Q	N-acetyltransferase	-	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
WH2_k127_6795596_2	869213.JCM21142_72909	3.582e-99	346.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,47JVQ@768503|Cytophagia	976|Bacteroidetes	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
WH2_k127_6795596_0	755732.Fluta_1888	2e-196	636.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1HX5G@117743|Flavobacteriia,2PA5A@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Penicillin binding protein transpeptidase domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
WH2_k127_6795596_5	929556.Solca_0353	5.211e-23	107.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,1ISUS@117747|Sphingobacteriia	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6795596_4	1392489.JPOL01000002_gene1108	1.538e-50	190.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,1HWJM@117743|Flavobacteriia,2XIH3@283735|Leeuwenhoekiella	976|Bacteroidetes	M	rod shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
WH2_k127_6795596_1	755732.Fluta_1895	3.402e-187	588.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,1HXDD@117743|Flavobacteriia,2PACA@246874|Cryomorphaceae	976|Bacteroidetes	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
WH2_k127_6795596_3	763034.HMPREF9446_01343	2.404e-92	308.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,2FN3G@200643|Bacteroidia,4AK6B@815|Bacteroidaceae	976|Bacteroidetes	F	bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
WH2_k127_6823147_0	926562.Oweho_1705	9.658e-228	716.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1HWS4@117743|Flavobacteriia,2PA9W@246874|Cryomorphaceae	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WH2_k127_6827833_1	755732.Fluta_3159	1.904e-29	125.0	2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,1HXZZ@117743|Flavobacteriia,2PAX7@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
WH2_k127_6827833_0	762903.Pedsa_1356	2.26e-38	146.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,1ISRC@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
WH2_k127_6827833_2	204669.Acid345_3121	1.067e-19	99.0	COG4430@1|root,COG4430@2|Bacteria,3Y5B3@57723|Acidobacteria,2JJNK@204432|Acidobacteriia	204432|Acidobacteriia	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
WH2_k127_6838750_0	755732.Fluta_1778	2.994e-79	291.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4PI0B@976|Bacteroidetes,1IG7A@117743|Flavobacteriia,2PBJ3@246874|Cryomorphaceae	976|Bacteroidetes	O	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
WH2_k127_6842741_1	1089547.KB913013_gene4561	4.203e-46	184.0	COG1404@1|root,COG3209@1|root,COG3391@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,4NPFV@976|Bacteroidetes	976|Bacteroidetes	MO	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6842741_0	1408433.JHXV01000030_gene1415	2.981e-66	237.0	COG3391@1|root,COG3391@2|Bacteria,4P12F@976|Bacteroidetes	976|Bacteroidetes	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_684521_1	2903.EOD05082	2.365e-14	87.0	COG5640@1|root,KOG3627@2759|Eukaryota	2759|Eukaryota	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	MAM,TIR_2,Trypsin
WH2_k127_684521_0	1094466.KQS_09370	3.431e-25	122.0	COG3227@1|root,COG3291@1|root,COG4412@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,4NJHV@976|Bacteroidetes,1IMXD@117743|Flavobacteriia,2NV4Y@237|Flavobacterium	976|Bacteroidetes	O	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
WH2_k127_6866420_2	929703.KE386491_gene4134	4.543e-43	168.0	COG0823@1|root,COG5384@1|root,COG0823@2|Bacteria,COG5384@2|Bacteria,4PKHZ@976|Bacteroidetes	976|Bacteroidetes	J	InterPro IPR003367	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,TSP_3
WH2_k127_6866420_3	326423.RBAM_028600	7.331e-40	151.0	COG3011@1|root,COG3011@2|Bacteria,1V7DJ@1239|Firmicutes,4HIUD@91061|Bacilli,1ZH0A@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
WH2_k127_6866420_1	1121889.AUDM01000011_gene2735	1.665e-131	430.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,1HYIB@117743|Flavobacteriia,2NTIR@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
WH2_k127_6866420_0	755732.Fluta_0865	4.908e-267	844.0	COG0475@1|root,COG0475@2|Bacteria,4NFPE@976|Bacteroidetes,1I0V4@117743|Flavobacteriia	976|Bacteroidetes	P	Transporter	nhaS3	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
WH2_k127_6872192_1	1122179.KB890413_gene4789	5.652e-27	130.0	COG1520@1|root,COG3391@1|root,COG4932@1|root,COG4935@1|root,COG1520@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,COG4935@2|Bacteria,4NN56@976|Bacteroidetes	976|Bacteroidetes	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS
WH2_k127_6872192_2	1123368.AUIS01000024_gene971	8.929e-26	126.0	COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,PKD,PQQ_2,RCC1_2,SBBP
WH2_k127_6872192_0	1089547.KB913013_gene4561	9.912e-36	142.0	COG1404@1|root,COG3209@1|root,COG3391@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,4NPFV@976|Bacteroidetes	976|Bacteroidetes	MO	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_6878596_1	504487.JCM19302_3220	1.188e-31	139.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1HY1I@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
WH2_k127_6878596_0	926562.Oweho_1972	1.415e-73	259.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1HX0P@117743|Flavobacteriia,2PAN2@246874|Cryomorphaceae	976|Bacteroidetes	M	NAD(P)H-binding	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
WH2_k127_6878596_2	269798.CHU_2652	0.0004643	48.0	2EK3P@1|root,33DU3@2|Bacteria,4NXK2@976|Bacteroidetes,47SN3@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4296)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4296
WH2_k127_6888110_0	1122139.KB907890_gene284	3.601e-68	239.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria,1XIDW@135619|Oceanospirillales	135619|Oceanospirillales	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
WH2_k127_6888110_2	313596.RB2501_03620	7.246e-30	130.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,1HX6W@117743|Flavobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
WH2_k127_6888110_1	1168034.FH5T_04015	2.913e-55	203.0	COG4797@1|root,COG4797@2|Bacteria,4PKQS@976|Bacteroidetes,2FP69@200643|Bacteroidia	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
WH2_k127_6906894_1	755732.Fluta_1637	2.689e-67	235.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1HXPY@117743|Flavobacteriia,2PA4Y@246874|Cryomorphaceae	976|Bacteroidetes	S	PSP1 C-terminal conserved region	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
WH2_k127_6906894_0	714943.Mucpa_3213	2.322e-89	307.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,1INPG@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2812 DNA polymerase III, gamma tau subunits	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
WH2_k127_6906894_2	1121373.KB903643_gene3663	1.091e-31	127.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,47K8V@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
WH2_k127_6913993_0	1122176.KB903546_gene1028	7.514e-113	380.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	manA5	-	3.2.1.51,3.2.1.78	ko:K01206,ko:K01218	ko00051,ko00511,ko02024,map00051,map00511,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko04147	-	GH26,GH29	-	Alpha_L_fucos,Cytochrome_C554,Glyco_hydro_26,PA14,RsgI_N
WH2_k127_6913993_1	945713.IALB_0147	1.648e-30	128.0	COG2234@1|root,COG4412@1|root,COG2234@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.11.10,3.4.21.50	ko:K01337,ko:K05994,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF4968,DUF5110,F5_F8_type_C,Glyco_hydro_31,PA,Peptidase_M28,Peptidase_M6,Peptidase_S8,W_rich_C
WH2_k127_6965050_0	755732.Fluta_1925	1.415e-131	426.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes,1ICQK@117743|Flavobacteriia,2PBS2@246874|Cryomorphaceae	976|Bacteroidetes	F	DeoC/LacD family aldolase	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
WH2_k127_6965050_1	1121012.AUKX01000001_gene1338	3.716e-16	89.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia,23I6P@178469|Arenibacter	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WH2_k127_6970829_1	641526.ADIWIN_1528	3.658e-32	138.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,1I21X@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
WH2_k127_6970829_0	927658.AJUM01000022_gene1152	1.705e-68	245.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,2FP6P@200643|Bacteroidia,3XJFG@558415|Marinilabiliaceae	976|Bacteroidetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
WH2_k127_6974477_1	468059.AUHA01000002_gene13	1.063e-43	160.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1IP19@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH2_k127_6974477_2	313596.RB2501_02125	5.728e-17	85.0	COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,1I50J@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
WH2_k127_6974477_0	1434325.AZQN01000003_gene1985	3.715e-72	254.0	COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,47JJY@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WH2_k127_6983204_2	1123248.KB893314_gene3437	8.47e-33	128.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1IPGS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
WH2_k127_6983204_0	1279009.ADICEAN_00658	1.616e-54	197.0	COG1670@1|root,COG1670@2|Bacteria,4NMTZ@976|Bacteroidetes,47SRK@768503|Cytophagia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
WH2_k127_6983204_1	1296415.JACC01000015_gene813	8.664e-44	170.0	COG1278@1|root,COG1278@2|Bacteria,4NNNH@976|Bacteroidetes,1I1ZM@117743|Flavobacteriia,2YH9T@290174|Aquimarina	976|Bacteroidetes	K	Cold shock protein domain	cspG	-	-	-	-	-	-	-	-	-	-	-	CSD
WH2_k127_6983204_3	592029.DDD_1674	1.46e-17	91.0	COG1286@1|root,COG1286@2|Bacteria,4NRG9@976|Bacteroidetes,1I2B6@117743|Flavobacteriia,3HK4J@363408|Nonlabens	976|Bacteroidetes	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
WH2_k127_6993526_0	1223410.KN050846_gene2065	7.406e-144	464.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1HY1I@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
WH2_k127_6996558_0	468059.AUHA01000002_gene691	5.816e-138	450.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1IQIS@117747|Sphingobacteriia	976|Bacteroidetes	S	phosphohydrolase	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
WH2_k127_6996558_1	682795.AciX8_0946	0.0001622	48.0	COG1874@1|root,COG1874@2|Bacteria,3Y6EF@57723|Acidobacteria,2JKVE@204432|Acidobacteriia	204432|Acidobacteriia	G	Domain of unknown function (DUF4832)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832
WH2_k127_7002447_0	1408433.JHXV01000018_gene3803	1.384e-50	197.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_7008131_2	357276.EL88_01440	1.066e-76	261.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,2FMSF@200643|Bacteroidia,4AKH7@815|Bacteroidaceae	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
WH2_k127_7008131_0	755732.Fluta_2284	1.596e-188	601.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1HX6T@117743|Flavobacteriia,2PAFK@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
WH2_k127_7008131_1	525373.HMPREF0766_10593	2.109e-80	270.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,1IPGA@117747|Sphingobacteriia	976|Bacteroidetes	K	ATPase (AAA	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
WH2_k127_7053833_0	755732.Fluta_1738	7.767e-137	445.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1HYG5@117743|Flavobacteriia,2PAGZ@246874|Cryomorphaceae	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
WH2_k127_7053833_1	1122931.AUAE01000008_gene4013	2.228e-52	198.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,2FSJZ@200643|Bacteroidia,231US@171551|Porphyromonadaceae	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH2_k127_7071651_4	435591.BDI_2777	2.724e-71	258.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,2FMKE@200643|Bacteroidia,22VZ1@171551|Porphyromonadaceae	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
WH2_k127_7071651_3	1227739.Hsw_1662	9.152e-100	356.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,47P7K@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
WH2_k127_7071651_1	1313421.JHBV01000004_gene705	1.334e-116	404.0	COG2089@1|root,COG2089@2|Bacteria,4NEKD@976|Bacteroidetes,1IRJN@117747|Sphingobacteriia	976|Bacteroidetes	M	synthase	neuB	-	2.5.1.101,2.5.1.132,2.5.1.56	ko:K01654,ko:K18430,ko:K21279	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
WH2_k127_7071651_2	313603.FB2170_05790	6.089e-100	340.0	COG0454@1|root,COG1082@1|root,COG0456@2|Bacteria,COG1082@2|Bacteria,4P2Y2@976|Bacteroidetes,1IAMZ@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
WH2_k127_7071651_0	1313421.JHBV01000004_gene708	1.692e-153	501.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes,1IT3E@117747|Sphingobacteriia	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
WH2_k127_7071651_5	635013.TherJR_2784	6.507e-22	101.0	COG1083@1|root,COG1083@2|Bacteria,1UFAT@1239|Firmicutes,24G5I@186801|Clostridia,262IY@186807|Peptococcaceae	186801|Clostridia	M	Cytidylyltransferase	neuA	-	2.7.7.82	ko:K18431	ko00520,map00520	-	R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
WH2_k127_707512_0	1313421.JHBV01000042_gene3261	4.978e-85	298.0	COG2353@1|root,COG3210@1|root,COG2353@2|Bacteria,COG3210@2|Bacteria,4NIDX@976|Bacteroidetes	976|Bacteroidetes	U	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
WH2_k127_707512_1	376686.Fjoh_0243	6.13e-62	218.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,1HY41@117743|Flavobacteriia,2NTKI@237|Flavobacterium	976|Bacteroidetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
WH2_k127_707728_1	1296415.JACC01000001_gene3634	2.649e-18	96.0	COG1572@1|root,COG4886@1|root,COG1572@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	3.4.21.72	ko:K01347	-	-	-	-	ko00000,ko01000,ko01002,ko02000,ko02044	1.B.12.3	-	-	Big_3,CHU_C,DUF285
WH2_k127_707728_0	153721.MYP_607	2.277e-58	207.0	COG1875@1|root,COG1875@2|Bacteria,4NDUI@976|Bacteroidetes,47M94@768503|Cytophagia	976|Bacteroidetes	T	PIN domain	ybeZ_1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
WH2_k127_7094917_0	1168289.AJKI01000035_gene3580	1.56e-129	428.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,2FMUA@200643|Bacteroidia,3XJ0M@558415|Marinilabiliaceae	976|Bacteroidetes	O	Trypsin	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
WH2_k127_7124021_0	313596.RB2501_02950	2.881e-43	166.0	COG0171@1|root,COG0171@2|Bacteria,4NEXG@976|Bacteroidetes,1HYCI@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
WH2_k127_7124021_2	509635.N824_08640	5.05e-28	123.0	2CJVV@1|root,336VZ@2|Bacteria,4NW8G@976|Bacteroidetes,1ITX6@117747|Sphingobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
WH2_k127_7124021_1	485918.Cpin_0219	2.531e-37	153.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,1IPUT@117747|Sphingobacteriia	976|Bacteroidetes	O	Gliding motility protein, GldB	gldB	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_7126000_0	926562.Oweho_0783	3.6e-108	372.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1HXWQ@117743|Flavobacteriia,2PANK@246874|Cryomorphaceae	976|Bacteroidetes	S	Bacillithiol biosynthesis BshC	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
WH2_k127_71295_0	1313421.JHBV01000019_gene5329	2.478e-70	258.0	COG2132@1|root,COG4935@1|root,COG2132@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	CHU_C,Copper-bind,Cu-oxidase_3,SprB
WH2_k127_7131019_0	1121481.AUAS01000005_gene2030	4.606e-47	177.0	COG3279@1|root,COG3279@2|Bacteria,4NK6R@976|Bacteroidetes,47XDW@768503|Cytophagia	976|Bacteroidetes	T	Two component transcriptional regulator, LytTR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
WH2_k127_7131019_1	1111069.TCCBUS3UF1_17270	1.813e-43	178.0	COG1572@1|root,COG1572@2|Bacteria,1WM7M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
WH2_k127_7141272_2	755732.Fluta_2846	5.735e-45	171.0	COG0064@1|root,COG0064@2|Bacteria,4NF3B@976|Bacteroidetes,1I8AX@117743|Flavobacteriia,2PAB3@246874|Cryomorphaceae	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
WH2_k127_7141272_0	755732.Fluta_2847	1.577e-105	349.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,1HWSP@117743|Flavobacteriia,2PA74@246874|Cryomorphaceae	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
WH2_k127_7141272_1	679199.HMPREF9332_00969	4.804e-48	183.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,2FN2X@200643|Bacteroidia,1WDA2@1283313|Alloprevotella	976|Bacteroidetes	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
WH2_k127_7143201_3	1168034.FH5T_11845	1.684e-13	73.0	2EJD3@1|root,33D44@2|Bacteria,4NYG1@976|Bacteroidetes,2FVDP@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
WH2_k127_7143201_2	1408433.JHXV01000009_gene1285	1.03e-57	214.0	COG3637@1|root,COG3637@2|Bacteria,4PJ16@976|Bacteroidetes,1ICQ3@117743|Flavobacteriia,2PBMQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_7143201_0	755732.Fluta_1867	3.07e-306	962.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,1HYR7@117743|Flavobacteriia,2PA7N@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
WH2_k127_7143201_1	1408813.AYMG01000011_gene801	6.075e-97	319.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,1IQJC@117747|Sphingobacteriia	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
WH2_k127_7158868_2	1121957.ATVL01000007_gene1582	1.213e-30	139.0	COG2931@1|root,COG2931@2|Bacteria,4P7R1@976|Bacteroidetes,47X32@768503|Cytophagia	976|Bacteroidetes	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_7158868_0	388413.ALPR1_10445	3.963e-48	181.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,47PTI@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
WH2_k127_7158868_1	485918.Cpin_1400	9.41e-34	136.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1IPPI@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
WH2_k127_7169652_1	1121438.JNJA01000011_gene1834	4.198e-19	89.0	COG0463@1|root,COG0463@2|Bacteria,1QTWH@1224|Proteobacteria,43CTF@68525|delta/epsilon subdivisions,2X80Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH2_k127_7169652_0	522306.CAP2UW1_0072	1.31e-198	639.0	COG0037@1|root,COG0449@1|root,COG0037@2|Bacteria,COG0449@2|Bacteria,1NKHX@1224|Proteobacteria,2VNZJ@28216|Betaproteobacteria	28216|Betaproteobacteria	D	ATPase of the PP-loop superfamily implicated in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6
WH2_k127_7181475_1	1392498.JQLH01000001_gene1296	4.764e-15	81.0	COG0789@1|root,COG0789@2|Bacteria,4NERC@976|Bacteroidetes,1HWT4@117743|Flavobacteriia,2PIKM@252356|Maribacter	976|Bacteroidetes	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,MerR_1
WH2_k127_7181475_0	1121889.AUDM01000009_gene1219	7.393e-125	414.0	COG5498@1|root,COG5498@2|Bacteria	2|Bacteria	M	chitin catabolic process	-	-	3.2.1.132	ko:K01233	ko00520,ko01100,map00520,map01100	-	R02833	-	ko00000,ko00001,ko01000	-	-	-	CBM_6,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_64,RicinB_lectin_2,fn3
WH2_k127_7216085_2	926562.Oweho_3093	7.806e-17	88.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,1HX93@117743|Flavobacteriia,2PANE@246874|Cryomorphaceae	976|Bacteroidetes	S	zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
WH2_k127_7216085_0	700598.Niako_5484	4.119e-125	411.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,1IP4G@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
WH2_k127_7216085_3	1121898.Q766_20750	0.0003126	51.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,2NU0I@237|Flavobacterium	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	fpp1	-	-	-	-	-	-	-	-	-	-	-	CUB,MAM,P_proprotein,Reprolysin_4,fn3
WH2_k127_7216085_1	1122176.KB903587_gene4486	1.65e-42	166.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes	976|Bacteroidetes	H	Gliding motility-associated C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
WH2_k127_7217113_0	1168289.AJKI01000031_gene972	1.732e-26	113.0	COG1188@1|root,COG1188@2|Bacteria,4NP8I@976|Bacteroidetes,2FRYM@200643|Bacteroidia,3XK4R@558415|Marinilabiliaceae	976|Bacteroidetes	J	S4 RNA-binding domain	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
WH2_k127_7217113_1	330214.NIDE0303	1.509e-13	83.0	COG0265@1|root,COG0265@2|Bacteria,3J0X9@40117|Nitrospirae	2|Bacteria	M	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	htrA	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
WH2_k127_7217113_2	706587.Desti_2706	5.466e-06	51.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,42TT1@68525|delta/epsilon subdivisions,2WQT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
WH2_k127_7232551_2	1144343.PMI41_03177	6.204e-05	50.0	COG3714@1|root,COG3714@2|Bacteria,1N6QN@1224|Proteobacteria	1224|Proteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
WH2_k127_7232551_1	56110.Oscil6304_1825	1.776e-21	109.0	COG1670@1|root,COG1670@2|Bacteria,1G5GV@1117|Cyanobacteria,1HAQ0@1150|Oscillatoriales	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
WH2_k127_7232551_0	509635.N824_23620	7.191e-112	371.0	COG3000@1|root,COG3000@2|Bacteria,4NFWX@976|Bacteroidetes,1IXQU@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
WH2_k127_723507_3	755732.Fluta_0900	2.927e-44	166.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1HYND@117743|Flavobacteriia,2PA5Y@246874|Cryomorphaceae	976|Bacteroidetes	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
WH2_k127_723507_0	929703.KE386491_gene1463	1.839e-145	466.0	COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,47JPC@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WH2_k127_723507_1	743722.Sph21_3092	4.088e-72	262.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1INSC@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
WH2_k127_723507_2	313606.M23134_05848	6.955e-67	238.0	COG1090@1|root,COG1090@2|Bacteria,4NINM@976|Bacteroidetes,47KA1@768503|Cytophagia	976|Bacteroidetes	S	PFAM NAD dependent epimerase dehydratase family	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
WH2_k127_7267213_0	1121889.AUDM01000005_gene1679	4.882e-114	375.0	COG2885@1|root,COG2885@2|Bacteria,4PPGM@976|Bacteroidetes,1IKM9@117743|Flavobacteriia,2P0S3@237|Flavobacterium	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_7267213_1	1121899.Q764_04475	4.124e-67	237.0	COG3781@1|root,COG3781@2|Bacteria,4NEB1@976|Bacteroidetes,1HYDP@117743|Flavobacteriia,2NSGY@237|Flavobacterium	976|Bacteroidetes	S	membrane	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
WH2_k127_7275352_1	1356852.N008_07420	1.014e-47	190.0	28MIW@1|root,2ZAVI@2|Bacteria,4P3DI@976|Bacteroidetes,47UX4@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_7275352_3	867902.Ornrh_0206	1.34e-06	55.0	COG2759@1|root,COG2759@2|Bacteria,4NG3E@976|Bacteroidetes,1HXR5@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
WH2_k127_7275352_4	1158345.JNLL01000001_gene1532	1.493e-06	56.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_3
WH2_k127_7275352_2	860228.Ccan_10730	7.412e-09	60.0	COG2759@1|root,COG2759@2|Bacteria,4NG3E@976|Bacteroidetes,1HXR5@117743|Flavobacteriia,1EREB@1016|Capnocytophaga	976|Bacteroidetes	H	Formyltetrahydrofolate synthetase	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
WH2_k127_7275352_0	1408433.JHXV01000005_gene2329	1.882e-175	557.0	COG2759@1|root,COG2759@2|Bacteria,4NG3E@976|Bacteroidetes,1HXR5@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
WH2_k127_7276462_2	755732.Fluta_2408	8.856e-11	70.0	2E7J5@1|root,3321E@2|Bacteria,4NWSR@976|Bacteroidetes,1I9ID@117743|Flavobacteriia,2PB0F@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
WH2_k127_7276462_0	745718.JADT01000001_gene1785	4.043e-158	508.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,1HX2U@117743|Flavobacteriia	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
WH2_k127_7276462_1	709991.Odosp_1604	4.569e-18	89.0	COG3187@1|root,COG3187@2|Bacteria,4NRFE@976|Bacteroidetes,2FQEM@200643|Bacteroidia	976|Bacteroidetes	O	COG3187 Heat shock protein	-	-	-	-	-	-	-	-	-	-	-	-	META
WH2_k127_7285020_1	1313421.JHBV01000039_gene2729	9.057e-15	82.0	COG3209@1|root,COG3291@1|root,COG4935@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NHWG@976|Bacteroidetes,1IRF4@117747|Sphingobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
WH2_k127_7285020_0	515635.Dtur_1285	1.933e-25	122.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_M8,Peptidase_S8,SLH
WH2_k127_7294318_2	1218103.CIN01S_13_00970	2.643e-09	63.0	COG4733@1|root,COG4733@2|Bacteria,4NIJT@976|Bacteroidetes,1IJZV@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5008,DUF5122
WH2_k127_7294318_0	925409.KI911562_gene344	3.485e-99	334.0	COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,1IPUJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22,4.6.1.17	ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
WH2_k127_7294318_1	1121957.ATVL01000008_gene4646	5.8e-72	278.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NK8Q@976|Bacteroidetes,47KVN@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
WH2_k127_7313624_1	886379.AEWI01000023_gene19	1.234e-32	128.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,2FSRY@200643|Bacteroidia,3XK4J@558415|Marinilabiliaceae	976|Bacteroidetes	FG	HIT domain	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
WH2_k127_7313624_0	926559.JoomaDRAFT_1302	9.659e-54	200.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,1HWX6@117743|Flavobacteriia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
WH2_k127_7313624_3	1356852.N008_01095	6.984e-25	120.0	COG0392@1|root,COG0392@2|Bacteria,4NI8Y@976|Bacteroidetes,47NMA@768503|Cytophagia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WH2_k127_7313624_2	471854.Dfer_2026	4.613e-28	129.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,47KYN@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
WH2_k127_733576_0	1122605.KB893638_gene3456	6.161e-173	553.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1IQ0B@117747|Sphingobacteriia	976|Bacteroidetes	P	Heavy metal translocating P-type atpase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WH2_k127_733576_2	666684.AfiDRAFT_1068	1.984e-06	53.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	-	-	3.6.3.4	ko:K01533,ko:K07213	ko04978,map04978	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	HMA
WH2_k127_733576_1	929713.NIASO_05555	2.783e-39	151.0	COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,1IQNG@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
WH2_k127_7348464_1	1120936.KB907209_gene1549	1.801e-17	83.0	COG0479@1|root,COG0479@2|Bacteria,2GJPS@201174|Actinobacteria,4EH4D@85012|Streptosporangiales	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
WH2_k127_7348464_0	1380384.JADN01000004_gene2146	1.502e-303	937.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,1HWUS@117743|Flavobacteriia	976|Bacteroidetes	C	SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
WH2_k127_7357820_3	755732.Fluta_0357	1.318e-99	340.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,1HX7I@117743|Flavobacteriia,2PABE@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Bacterial trigger factor protein (TF)	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
WH2_k127_7357820_2	1461577.CCMH01000045_gene823	7.031e-101	337.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,1HWT0@117743|Flavobacteriia	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
WH2_k127_7357820_1	1408433.JHXV01000011_gene2092	2.466e-108	356.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,1HWT0@117743|Flavobacteriia,2PA6J@246874|Cryomorphaceae	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
WH2_k127_7357820_0	385682.AFSL01000060_gene1758	7.932e-177	565.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,2FMQV@200643|Bacteroidia,3XIWM@558415|Marinilabiliaceae	976|Bacteroidetes	O	ClpX C4-type zinc finger	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
WH2_k127_7357820_5	1341181.FLJC2902T_26400	4.858e-61	222.0	COG0790@1|root,COG0790@2|Bacteria,4NGW3@976|Bacteroidetes,1HY27@117743|Flavobacteriia,2NSPG@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
WH2_k127_7357820_4	926550.CLDAP_32550	2.154e-71	248.0	COG1028@1|root,COG1028@2|Bacteria,2G8YX@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.206	ko:K08081	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R02832	RC00144	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
WH2_k127_7381153_0	926550.CLDAP_32490	2.574e-17	96.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
WH2_k127_7385109_0	1123277.KB893217_gene4672	2.651e-146	469.0	COG2192@1|root,COG2192@2|Bacteria,4NEV9@976|Bacteroidetes,47JR5@768503|Cytophagia	976|Bacteroidetes	O	PFAM Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
WH2_k127_7385109_1	927658.AJUM01000034_gene365	1.338e-36	145.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,2FPNI@200643|Bacteroidia,3XJDE@558415|Marinilabiliaceae	976|Bacteroidetes	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
WH2_k127_7399946_2	755732.Fluta_2090	2.738e-06	50.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
WH2_k127_7399946_0	755732.Fluta_2021	2.112e-80	295.0	COG3291@1|root,COG3291@2|Bacteria,4PFQY@976|Bacteroidetes,1ICPB@117743|Flavobacteriia,2PBH6@246874|Cryomorphaceae	976|Bacteroidetes	S	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta
WH2_k127_7399946_3	1461577.CCMH01000011_gene1739	0.0006314	45.0	COG1404@1|root,COG5492@1|root,COG1404@2|Bacteria,COG5492@2|Bacteria,4PM4C@976|Bacteroidetes,1IJJ4@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,Reprolysin_4,fn3
WH2_k127_7399946_1	357808.RoseRS_0459	6.738e-08	65.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
WH2_k127_7436778_2	1121912.AUHD01000004_gene1999	9.035e-39	164.0	COG4386@1|root,COG4886@1|root,COG4386@2|Bacteria,COG4886@2|Bacteria,4PPDK@976|Bacteroidetes,1IKIZ@117743|Flavobacteriia	976|Bacteroidetes	E	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
WH2_k127_7436778_4	880073.Calab_1872	5.52e-05	56.0	COG3630@1|root,COG5337@1|root,COG3630@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD,OAD_gamma
WH2_k127_7436778_3	1122176.KB903542_gene353	5.808e-19	102.0	COG5337@1|root,COG5337@2|Bacteria,4NEH2@976|Bacteroidetes	976|Bacteroidetes	M	sodium ion export across plasma membrane	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
WH2_k127_7436778_1	468059.AUHA01000002_gene1130	9.562e-96	318.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1IRA4@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
WH2_k127_7436778_5	1538644.KO02_03135	6.527e-05	54.0	28H89@1|root,2Z7K8@2|Bacteria,4NEKX@976|Bacteroidetes,1IPQD@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_7436778_0	742725.HMPREF9450_00126	2.003e-108	359.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,2FN59@200643|Bacteroidia,22TZ6@171550|Rikenellaceae	976|Bacteroidetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
WH2_k127_7437751_0	1356852.N008_21490	5.887e-142	467.0	COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,47KFP@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor	-	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WH2_k127_7443980_3	313596.RB2501_01670	2.746e-53	194.0	COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes,1I18R@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
WH2_k127_7443980_1	926562.Oweho_1060	2.598e-57	211.0	COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,1IJP8@117743|Flavobacteriia,2PB5D@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
WH2_k127_7443980_0	755732.Fluta_2877	3.246e-103	348.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,1HX8P@117743|Flavobacteriia,2PA6B@246874|Cryomorphaceae	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
WH2_k127_7443980_5	1151122.AQYD01000007_gene1455	3.781e-05	51.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4FNPN@85023|Microbacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
WH2_k127_7443980_2	925409.KI911562_gene2267	1.985e-56	201.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,1ISC1@117747|Sphingobacteriia	976|Bacteroidetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
WH2_k127_7443980_4	1408433.JHXV01000010_gene508	6.977e-40	161.0	29N3N@1|root,33PNI@2|Bacteria,4P1TW@976|Bacteroidetes,1IMS9@117743|Flavobacteriia,2PBW3@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_7506807_0	1392490.JHZX01000001_gene869	9.809e-151	514.0	COG1361@1|root,COG4886@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,4NG93@976|Bacteroidetes,1HXFW@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
WH2_k127_7512960_1	1121101.HMPREF1532_01414	1.116e-29	119.0	COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,2FMTB@200643|Bacteroidia,4AKBK@815|Bacteroidaceae	976|Bacteroidetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10,4.1.1.23	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
WH2_k127_7512960_2	1408433.JHXV01000002_gene316	5.398e-29	121.0	COG3427@1|root,COG3427@2|Bacteria,4PHJK@976|Bacteroidetes,1IGIK@117743|Flavobacteriia,2PB7C@246874|Cryomorphaceae	976|Bacteroidetes	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_7512960_0	1123035.ARLA01000028_gene2071	4.98e-155	505.0	COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,1HYJM@117743|Flavobacteriia,4C2WF@83612|Psychroflexus	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
WH2_k127_7519974_1	1121898.Q766_16415	8.113e-67	233.0	COG4389@1|root,COG4389@2|Bacteria,4NH21@976|Bacteroidetes,1HX7W@117743|Flavobacteriia,2NUQ3@237|Flavobacterium	976|Bacteroidetes	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	SpecificRecomb
WH2_k127_7519974_0	1454007.JAUG01000054_gene2592	2.319e-241	788.0	COG0383@1|root,COG0383@2|Bacteria,4NGF5@976|Bacteroidetes,1IPJQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 38 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_38,Glyco_hydro_38C
WH2_k127_7546975_1	926562.Oweho_1092	3.737e-32	141.0	2ENP2@1|root,33GAE@2|Bacteria,4NZIT@976|Bacteroidetes,1I8VS@117743|Flavobacteriia,2PB29@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_7546975_0	1313301.AUGC01000004_gene2420	1.783e-47	181.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes	976|Bacteroidetes	S	of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
WH2_k127_7565829_0	755732.Fluta_1177	2.189e-241	750.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1HXYZ@117743|Flavobacteriia,2PAMC@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Cytochrome C and Quinol oxidase polypeptide I	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
WH2_k127_7575393_0	153721.MYP_3320	6.971e-159	519.0	COG0277@1|root,COG0277@2|Bacteria,4NIAB@976|Bacteroidetes,47NIH@768503|Cytophagia	976|Bacteroidetes	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
WH2_k127_7575393_3	1443665.JACA01000007_gene122	9.499e-08	64.0	2DS5H@1|root,33EMJ@2|Bacteria,4NY2R@976|Bacteroidetes,1IM4C@117743|Flavobacteriia,2YJUW@290174|Aquimarina	976|Bacteroidetes	S	Bor protein	-	-	-	-	-	-	-	-	-	-	-	-	Lambda_Bor
WH2_k127_7575393_1	1107311.Q767_09410	4.57e-68	246.0	COG2159@1|root,COG2159@2|Bacteria,4P1JX@976|Bacteroidetes,1I7FR@117743|Flavobacteriia,2NXG2@237|Flavobacterium	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
WH2_k127_7575393_2	1107311.Q767_09415	2.885e-08	56.0	28MCN@1|root,30KCD@2|Bacteria,4P9R9@976|Bacteroidetes,1INFZ@117743|Flavobacteriia,2NZGY@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_7588827_0	1313421.JHBV01000028_gene1857	4.43e-109	370.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
WH2_k127_7590498_0	1392490.JHZX01000001_gene3178	2.083e-48	194.0	COG2706@1|root,COG4886@1|root,COG2706@2|Bacteria,COG4886@2|Bacteria,4NFXV@976|Bacteroidetes,1I00F@117743|Flavobacteriia	976|Bacteroidetes	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
WH2_k127_7599272_1	1408433.JHXV01000037_gene2580	3.493e-34	138.0	COG4068@1|root,COG4068@2|Bacteria,4NQ3Z@976|Bacteroidetes,1I2T2@117743|Flavobacteriia,2PB51@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
WH2_k127_7599272_0	264730.PSPPH_1390	2.173e-75	258.0	COG1236@1|root,COG1236@2|Bacteria,1MV7U@1224|Proteobacteria,1RYA5@1236|Gammaproteobacteria,1Z8VH@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	-
WH2_k127_7607834_0	1122176.KB903539_gene1381	5.633e-244	764.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1IV4C@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
WH2_k127_7607834_2	1089550.ATTH01000001_gene1602	8.674e-48	190.0	COG0400@1|root,COG0400@2|Bacteria,4NHWT@976|Bacteroidetes,1FJF1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Serine hydrolase (FSH1)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,FSH1
WH2_k127_7607834_1	1124780.ANNU01000016_gene1823	3.441e-227	721.0	COG0308@1|root,COG0308@2|Bacteria,4NFT0@976|Bacteroidetes,47M3W@768503|Cytophagia	976|Bacteroidetes	E	Leukotriene A4 hydrolase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
WH2_k127_7607834_3	1048983.EL17_14410	1.151e-23	104.0	COG2827@1|root,COG2827@2|Bacteria,4NVHC@976|Bacteroidetes,47RW6@768503|Cytophagia	976|Bacteroidetes	L	PFAM GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
WH2_k127_7619133_0	755732.Fluta_2738	6.984e-201	644.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1HWVX@117743|Flavobacteriia,2PB6G@246874|Cryomorphaceae	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
WH2_k127_7619133_1	1008457.BAEX01000022_gene1973	2.268e-39	155.0	COG1670@1|root,COG1670@2|Bacteria,4NNT2@976|Bacteroidetes,1I3AA@117743|Flavobacteriia,47IDJ@76831|Myroides	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
WH2_k127_7619133_2	1123277.KB893173_gene1501	5.569e-30	121.0	COG0697@1|root,COG0697@2|Bacteria,4NGJR@976|Bacteroidetes,47PYM@768503|Cytophagia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WH2_k127_7632357_4	153721.MYP_4029	2.897e-38	162.0	COG0457@1|root,COG0457@2|Bacteria,4NIEU@976|Bacteroidetes,47XPU@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
WH2_k127_7632357_3	926549.KI421517_gene381	6.162e-40	159.0	COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes,47NNB@768503|Cytophagia	976|Bacteroidetes	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
WH2_k127_7632357_1	1121481.AUAS01000003_gene3861	1.467e-48	184.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,47XHA@768503|Cytophagia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WH2_k127_7632357_5	755732.Fluta_1108	4.306e-35	143.0	COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,1I08G@117743|Flavobacteriia	976|Bacteroidetes	U	Biopolymer transporter ExbD	exbD2	-	-	-	-	-	-	-	-	-	-	-	ExbD
WH2_k127_7632357_2	926549.KI421517_gene377	9.126e-43	165.0	COG0848@1|root,COG0848@2|Bacteria,4NMT4@976|Bacteroidetes,47NTX@768503|Cytophagia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD1	-	-	-	-	-	-	-	-	-	-	-	ExbD
WH2_k127_7632357_0	1121957.ATVL01000010_gene506	1.013e-82	284.0	COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,47MMA@768503|Cytophagia	976|Bacteroidetes	U	MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
WH2_k127_7636139_0	1121889.AUDM01000010_gene584	2.578e-82	287.0	COG3291@1|root,COG3291@2|Bacteria,4NM0P@976|Bacteroidetes,1I0CF@117743|Flavobacteriia,2P0BI@237|Flavobacterium	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M14
WH2_k127_7636139_1	1443665.JACA01000026_gene3582	6.814e-44	179.0	COG0730@1|root,COG0730@2|Bacteria,4NFTT@976|Bacteroidetes,1HWXF@117743|Flavobacteriia,2YKEA@290174|Aquimarina	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WH2_k127_7636139_2	1303692.SFUL_302	8.718e-12	71.0	COG5646@1|root,COG5646@2|Bacteria,2IMR2@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WH2_k127_7636545_1	760192.Halhy_3819	2.986e-70	248.0	COG0308@1|root,COG0842@1|root,COG1277@1|root,COG0308@2|Bacteria,COG0842@2|Bacteria,COG1277@2|Bacteria,4NF3R@976|Bacteroidetes,1IPQP@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WH2_k127_7636545_0	1166018.FAES_5300	7.297e-133	432.0	COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,47KHD@768503|Cytophagia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WH2_k127_7636545_2	1122605.KB893626_gene2552	7.264e-64	223.0	COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes	976|Bacteroidetes	E	Tryptophanase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WH2_k127_7641139_3	1121285.AUFK01000002_gene76	2.897e-11	70.0	COG1057@1|root,COG1057@2|Bacteria,4NEIR@976|Bacteroidetes,1HWWY@117743|Flavobacteriia,3ZQDF@59732|Chryseobacterium	976|Bacteroidetes	H	Nicotinate-nucleotide adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_7641139_2	984262.SGRA_2019	3.779e-22	100.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,4NFUD@976|Bacteroidetes,1IPBH@117747|Sphingobacteriia	976|Bacteroidetes	H	UBA THIF-type NAD FAD binding protein	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
WH2_k127_7641139_0	755732.Fluta_3660	1.289e-106	362.0	COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,1IMQP@117743|Flavobacteriia,2PBFH@246874|Cryomorphaceae	976|Bacteroidetes	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
WH2_k127_7641139_1	762903.Pedsa_3037	2.522e-54	201.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
WH2_k127_7649_1	1356852.N008_01240	1.84e-76	267.0	COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,47KEY@768503|Cytophagia	976|Bacteroidetes	S	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
WH2_k127_7649_0	946077.W5A_08492	1.991e-216	685.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1HY2B@117743|Flavobacteriia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
WH2_k127_7663116_0	1313421.JHBV01000029_gene2007	2.002e-74	257.0	2DBF0@1|root,2Z8VT@2|Bacteria,4NECW@976|Bacteroidetes	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	1.3.1.22	ko:K12343	ko00140,map00140	-	R02208,R02497,R08954,R10242	RC00145	ko00000,ko00001,ko01000	-	-	-	Steroid_dh
WH2_k127_7663116_1	391625.PPSIR1_16360	1.148e-66	239.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2YXN2@29|Myxococcales	28221|Deltaproteobacteria	GM	epimerase dehydratase	hpnA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
WH2_k127_7663116_2	153721.MYP_3089	9.573e-08	56.0	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,47MD4@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
WH2_k127_7670185_1	448385.sce6661	1.774e-14	80.0	COG1520@1|root,COG2374@1|root,COG5184@1|root,COG1520@2|Bacteria,COG2374@2|Bacteria,COG5184@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria	1224|Proteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
WH2_k127_7670185_0	1122176.KB903598_gene4712	5.052e-100	354.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CW_binding_1,HYR
WH2_k127_7670185_2	234621.RER_31910	0.0004742	44.0	COG0477@1|root,COG2814@2|Bacteria,2I9WU@201174|Actinobacteria,4FZ39@85025|Nocardiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH2_k127_7695676_4	1313421.JHBV01000016_gene5472	7.948e-42	167.0	COG0438@1|root,COG0438@2|Bacteria,4NG0D@976|Bacteroidetes	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WH2_k127_7695676_3	595536.ADVE02000001_gene994	1.799e-47	181.0	COG4627@1|root,COG4627@2|Bacteria,1NKXY@1224|Proteobacteria	1224|Proteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
WH2_k127_7695676_1	643867.Ftrac_2226	1.789e-49	187.0	COG0463@1|root,COG0463@2|Bacteria,4P0WQ@976|Bacteroidetes,47YDM@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	2.4.1.293	ko:K17250	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WH2_k127_7695676_0	700598.Niako_6768	1.07e-109	376.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WH2_k127_7695676_2	643867.Ftrac_2222	2.671e-49	190.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.11	ko:K16150	ko00500,ko01100,map00500,map01100	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
WH2_k127_7720053_1	1123277.KB893206_gene3298	9.2e-15	77.0	COG2761@1|root,COG2761@2|Bacteria,4NI0H@976|Bacteroidetes,47KMR@768503|Cytophagia	976|Bacteroidetes	Q	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_5
WH2_k127_7720053_0	314230.DSM3645_14830	5.713e-78	265.0	COG3059@1|root,COG3059@2|Bacteria,2IWZI@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function, DUF417	-	-	-	ko:K21741	-	-	-	-	ko00000	-	-	-	DUF417
WH2_k127_7733577_0	859653.HIMB5_00002630	1.749e-196	627.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2TVZI@28211|Alphaproteobacteria,4BPQG@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Formate dehydrogenase, alpha subunit	fdsA	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WH2_k127_7738470_0	929556.Solca_3976	3.754e-121	404.0	COG4870@1|root,COG4870@2|Bacteria,4NGK1@976|Bacteroidetes,1INPA@117747|Sphingobacteriia	976|Bacteroidetes	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,Peptidase_C1
WH2_k127_7746257_0	1107311.Q767_01615	3.639e-46	185.0	COG1520@1|root,COG3291@1|root,COG3386@1|root,COG5306@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5306@2|Bacteria,4NNUN@976|Bacteroidetes,1IKME@117743|Flavobacteriia,2NXAD@237|Flavobacterium	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,SBBP
WH2_k127_7748301_0	762903.Pedsa_0201	1.086e-125	417.0	COG0477@1|root,COG0477@2|Bacteria,4PKN6@976|Bacteroidetes,1J0M5@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH2_k127_7748301_1	755732.Fluta_0638	5.909e-10	65.0	COG3204@1|root,COG3204@2|Bacteria,4NNIP@976|Bacteroidetes,1I2A1@117743|Flavobacteriia,2PBKP@246874|Cryomorphaceae	976|Bacteroidetes	S	SdiA-regulated	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
WH2_k127_7761938_1	1166018.FAES_2815	6.411e-111	369.0	COG3187@1|root,COG3187@2|Bacteria,4NEY0@976|Bacteroidetes,47K7R@768503|Cytophagia	976|Bacteroidetes	O	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3,META
WH2_k127_7761938_0	1122179.KB890432_gene4108	3.863e-166	541.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1IPS9@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WH2_k127_7782238_0	755732.Fluta_1892	2.114e-162	529.0	COG1520@1|root,COG2312@1|root,COG4386@1|root,COG1520@2|Bacteria,COG2312@2|Bacteria,COG4386@2|Bacteria,4PP0J@976|Bacteroidetes	976|Bacteroidetes	E	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD
WH2_k127_7782238_1	746697.Aeqsu_0245	4.461e-05	47.0	2DBTS@1|root,2ZB0P@2|Bacteria,4NGP7@976|Bacteroidetes,1IKCE@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
WH2_k127_778535_0	1203611.KB894550_gene962	3.234e-134	434.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,2FMD1@200643|Bacteroidia,22UAE@171550|Rikenellaceae	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WH2_k127_778535_2	1223410.KN050846_gene193	1.955e-61	225.0	COG0318@1|root,COG0318@2|Bacteria,4NEXK@976|Bacteroidetes,1HX5P@117743|Flavobacteriia	976|Bacteroidetes	IQ	O-succinylbenzoic acid--CoA ligase	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
WH2_k127_778535_1	1121129.KB903360_gene3346	1.032e-72	250.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,2FMXR@200643|Bacteroidia,22X1A@171551|Porphyromonadaceae	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	menC	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
WH2_k127_7811257_0	1122176.KB903532_gene2723	6.102e-17	83.0	COG3279@1|root,COG3279@2|Bacteria,4NKXC@976|Bacteroidetes,1ITHP@117747|Sphingobacteriia	976|Bacteroidetes	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
WH2_k127_7811257_1	1123248.KB893337_gene2408	8.372e-14	83.0	COG0729@1|root,COG3210@1|root,COG0729@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Bac_surface_Ag,Peptidase_S74
WH2_k127_7815201_0	153721.MYP_2994	3.278e-06	60.0	COG2931@1|root,COG3209@1|root,COG3210@1|root,COG4447@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4447@2|Bacteria,4NE5D@976|Bacteroidetes,47MBZ@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_7827598_0	929556.Solca_2664	1.3e-270	880.0	COG2374@1|root,COG3209@1|root,COG3210@1|root,COG3391@1|root,COG4886@1|root,COG4932@1|root,COG5492@1|root,COG2374@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
WH2_k127_7831083_0	755732.Fluta_1778	2.352e-83	297.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4PI0B@976|Bacteroidetes,1IG7A@117743|Flavobacteriia,2PBJ3@246874|Cryomorphaceae	976|Bacteroidetes	O	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
WH2_k127_7853494_0	485918.Cpin_1867	1.257e-51	193.0	COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,1ISE9@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
WH2_k127_7853494_1	1356852.N008_02075	6.21e-05	48.0	COG4313@1|root,COG4313@2|Bacteria,4NIIB@976|Bacteroidetes,47SDW@768503|Cytophagia	976|Bacteroidetes	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
WH2_k127_7855783_0	700598.Niako_4281	1.445e-16	89.0	COG2885@1|root,COG5295@1|root,COG2885@2|Bacteria,COG5295@2|Bacteria,4NN21@976|Bacteroidetes	976|Bacteroidetes	UW	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA14
WH2_k127_7855783_1	984262.SGRA_2624	0.000475	51.0	COG1572@1|root,COG3209@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
WH2_k127_785943_3	1410608.JNKX01000059_gene82	0.0002592	49.0	COG0834@1|root,COG0834@2|Bacteria,4NT4Q@976|Bacteroidetes,2FV88@200643|Bacteroidia,4AUPW@815|Bacteroidaceae	976|Bacteroidetes	ET	Bacterial periplasmic substrate-binding proteins	-	-	4.2.1.51,4.2.1.91	ko:K01713	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	SBP_bac_3
WH2_k127_785943_1	485918.Cpin_7200	1.942e-13	72.0	COG1722@1|root,COG1722@2|Bacteria,4NWXT@976|Bacteroidetes,1IUJ3@117747|Sphingobacteriia	976|Bacteroidetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	-	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
WH2_k127_785943_0	1515613.HQ37_06550	3.669e-62	233.0	COG1570@1|root,COG1570@2|Bacteria,4NE64@976|Bacteroidetes,2FMMA@200643|Bacteroidia,22WD7@171551|Porphyromonadaceae	976|Bacteroidetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
WH2_k127_785943_2	592029.DDD_2694	6.465e-05	48.0	COG3668@1|root,COG3668@2|Bacteria,4NWEI@976|Bacteroidetes,1I50C@117743|Flavobacteriia	976|Bacteroidetes	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
WH2_k127_7886198_0	313606.M23134_02237	3.306e-76	276.0	COG3209@1|root,COG3291@1|root,COG3386@1|root,COG4932@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,4NJ9V@976|Bacteroidetes,47N8F@768503|Cytophagia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
WH2_k127_7886198_2	1123037.AUDE01000019_gene3226	9.185e-22	110.0	COG1361@1|root,COG1361@2|Bacteria,4NMB8@976|Bacteroidetes,1I0EW@117743|Flavobacteriia	976|Bacteroidetes	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG
WH2_k127_7886198_1	1408473.JHXO01000010_gene3702	8.074e-75	263.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,2FTFG@200643|Bacteroidia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
WH2_k127_7886198_3	1453498.LG45_12545	1.748e-12	73.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia,2NSMW@237|Flavobacterium	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
WH2_k127_7886994_1	1408813.AYMG01000012_gene952	1.254e-72	267.0	COG1738@1|root,COG1738@2|Bacteria,4NFP3@976|Bacteroidetes,1IQJP@117747|Sphingobacteriia	976|Bacteroidetes	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
WH2_k127_7886994_0	1122236.KB905143_gene168	3.232e-108	361.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2VHKV@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
WH2_k127_7889873_1	385682.AFSL01000003_gene1912	5.67e-51	185.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,2G24U@200643|Bacteroidia,3XK3Q@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
WH2_k127_7889873_0	1408433.JHXV01000017_gene1629	1.534e-93	319.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,1I942@117743|Flavobacteriia,2PBH5@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran
WH2_k127_7896847_6	531844.FIC_01005	0.0008481	45.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1HYN2@117743|Flavobacteriia	976|Bacteroidetes	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
WH2_k127_7896847_3	794903.OPIT5_11735	2.789e-57	208.0	COG0500@1|root,COG0500@2|Bacteria,46V7N@74201|Verrucomicrobia,3K8BC@414999|Opitutae	414999|Opitutae	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WH2_k127_7896847_1	1227739.Hsw_1082	8.198e-127	421.0	COG0644@1|root,COG0644@2|Bacteria,4NKR8@976|Bacteroidetes,47U5U@768503|Cytophagia	976|Bacteroidetes	C	FAD binding domain	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
WH2_k127_7896847_0	1408433.JHXV01000015_gene1775	2.284e-138	449.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,1HWWV@117743|Flavobacteriia,2PAHY@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
WH2_k127_7896847_2	1313421.JHBV01000007_gene4311	1.32e-64	231.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,1IRYC@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	PKD,Pro_isomerase
WH2_k127_7896847_5	1408433.JHXV01000015_gene1774	3.74e-13	76.0	2A5H4@1|root,30U7A@2|Bacteria,4PFFN@976|Bacteroidetes,1IMTB@117743|Flavobacteriia,2PC40@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_7896847_4	755732.Fluta_1169	9.062e-30	120.0	29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,1I1Z8@117743|Flavobacteriia,2PB6N@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_7914663_3	1124780.ANNU01000010_gene3599	3.848e-06	58.0	COG1621@1|root,COG1621@2|Bacteria,4NI8X@976|Bacteroidetes	976|Bacteroidetes	G	Glycosyl hydrolases family 32	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N,Laminin_G_3
WH2_k127_7914663_1	485918.Cpin_2595	7.308e-91	308.0	COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,1IRHE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Bacterial lipid A biosynthesis acyltransferase	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
WH2_k127_7914663_0	700598.Niako_5173	1.919e-114	378.0	COG3239@1|root,COG3239@2|Bacteria,4NNB2@976|Bacteroidetes,1IZDH@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
WH2_k127_7939711_2	877418.ATWV01000006_gene2074	0.0004688	46.0	COG1848@1|root,COG1848@2|Bacteria,2J83D@203691|Spirochaetes	203691|Spirochaetes	S	PIN domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
WH2_k127_7939711_0	714943.Mucpa_0134	8.602e-19	93.0	COG3209@1|root,COG4223@1|root,COG3209@2|Bacteria,COG4223@2|Bacteria,4NE5D@976|Bacteroidetes,1IP6I@117747|Sphingobacteriia	976|Bacteroidetes	M	YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,TSP_3
WH2_k127_7939711_1	866536.Belba_3163	1.141e-07	63.0	COG2374@1|root,COG2374@2|Bacteria,4NHFV@976|Bacteroidetes,47M74@768503|Cytophagia	976|Bacteroidetes	M	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHB_HEX_C_1,Exo_endo_phos
WH2_k127_7941116_0	1550091.JROE01000010_gene3155	5.827e-90	304.0	COG0332@1|root,COG0332@2|Bacteria,4NE5Q@976|Bacteroidetes,1IPV9@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	darB	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III_C,Thiolase_N,ketoacyl-synt
WH2_k127_7941116_1	553177.CAPSP0001_1213	1.857e-60	225.0	COG0716@1|root,COG0716@2|Bacteria,4NHTB@976|Bacteroidetes,1HWMC@117743|Flavobacteriia,1EQSX@1016|Capnocytophaga	976|Bacteroidetes	C	Dialkylrecorsinol condensing enzyme DarA	darA	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_7941116_2	760192.Halhy_2897	2.577e-33	132.0	COG1216@1|root,COG1216@2|Bacteria,4NGHQ@976|Bacteroidetes,1IS78@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0463 Glycosyltransferase involved in cell wall biogenesis	-	-	-	ko:K13002	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
WH2_k127_7982610_2	1123248.KB893359_gene2213	4.647e-34	137.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,TPR_12,Y_Y_Y
WH2_k127_7982610_1	929713.NIASO_00340	1.183e-58	210.0	COG2197@1|root,COG2197@2|Bacteria,4NNQH@976|Bacteroidetes,1J05Y@117747|Sphingobacteriia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH2_k127_7982610_0	1239962.C943_02799	2.36e-83	304.0	COG2114@1|root,COG3292@1|root,COG2114@2|Bacteria,COG3292@2|Bacteria,4NEVN@976|Bacteroidetes,47MR3@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,Reg_prop,Response_reg,TPR_12,Y_Y_Y
WH2_k127_7984035_1	693979.Bache_1176	2.285e-67	233.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,2FN2K@200643|Bacteroidia,4AK73@815|Bacteroidaceae	976|Bacteroidetes	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
WH2_k127_7984035_0	1227739.Hsw_0324	3.388e-214	696.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,47JKP@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
WH2_k127_7984035_2	1313421.JHBV01000042_gene3235	4.433e-42	164.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1ITAS@117747|Sphingobacteriia	976|Bacteroidetes	O	Serine protease, subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WH2_k127_7986285_0	869213.JCM21142_41506	7.735e-86	294.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,47JDH@768503|Cytophagia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
WH2_k127_7986285_2	680198.SCAB_14441	4.885e-17	85.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
WH2_k127_7986285_1	1279009.ADICEAN_00311	7.933e-60	220.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,47JI9@768503|Cytophagia	976|Bacteroidetes	E	PFAM FAD dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
WH2_k127_7990176_0	762903.Pedsa_2021	1.113e-290	917.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1IQ2F@117747|Sphingobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
WH2_k127_7990176_1	755732.Fluta_2435	1.963e-152	490.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes,1HXN9@117743|Flavobacteriia,2PBAS@246874|Cryomorphaceae	976|Bacteroidetes	Q	Fumarylacetoacetate (FAA) hydrolase family	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
WH2_k127_8012835_6	1408433.JHXV01000033_gene1154	2.829e-46	180.0	28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,1I791@117743|Flavobacteriia,2PA5S@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8012835_4	1089547.KB913013_gene2415	1.792e-66	236.0	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,47JQR@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
WH2_k127_8012835_2	1501391.LG35_04900	1.878e-69	244.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia,22UAZ@171550|Rikenellaceae	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
WH2_k127_8012835_5	313606.M23134_07227	2.938e-47	175.0	COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,47PV8@768503|Cytophagia	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
WH2_k127_8012835_0	1124780.ANNU01000010_gene3651	7.822e-144	484.0	COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes,47MT8@768503|Cytophagia	976|Bacteroidetes	Q	phytoene	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
WH2_k127_8012835_1	1408433.JHXV01000033_gene1151	3.026e-72	261.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1HXE7@117743|Flavobacteriia,2PB0U@246874|Cryomorphaceae	976|Bacteroidetes	S	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
WH2_k127_8012835_3	592029.DDD_0457	1.016e-67	234.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,1HWSC@117743|Flavobacteriia,3HJFE@363408|Nonlabens	976|Bacteroidetes	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
WH2_k127_8013438_0	1279009.ADICEAN_00940	2.872e-169	557.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,47MDC@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
WH2_k127_8014124_3	755732.Fluta_2606	6.988e-57	211.0	28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,1I8RM@117743|Flavobacteriia	976|Bacteroidetes	S	S1 P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease,Zn_dep_PLPC
WH2_k127_8014124_0	755732.Fluta_2607	7.528e-71	252.0	COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,1IMQY@117743|Flavobacteriia,2PBHE@246874|Cryomorphaceae	976|Bacteroidetes	H	2-phosphosulpholactate phosphatase	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
WH2_k127_8014124_1	1041826.FCOL_00780	4.335e-63	224.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1HYBS@117743|Flavobacteriia,2NSF0@237|Flavobacterium	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
WH2_k127_8014124_2	1121405.dsmv_2114	2.554e-62	218.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria,2MI8G@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Belongs to the TtcA family	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
WH2_k127_8022561_0	385682.AFSL01000022_gene2112	7.035e-75	261.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,2FMVX@200643|Bacteroidia,3XJQ3@558415|Marinilabiliaceae	976|Bacteroidetes	S	YceG-like family	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
WH2_k127_8022561_1	491205.JARQ01000002_gene139	2.505e-42	163.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,1HY3U@117743|Flavobacteriia,3ZPD2@59732|Chryseobacterium	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
WH2_k127_8047078_1	865938.Weevi_1203	6.134e-21	96.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,1I28E@117743|Flavobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
WH2_k127_8047078_0	1453500.AT05_03545	1.119e-241	751.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1HXGV@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
WH2_k127_8052594_0	1121033.AUCF01000014_gene1279	3.192e-104	349.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TSGF@28211|Alphaproteobacteria,2JPV5@204441|Rhodospirillales	204441|Rhodospirillales	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WH2_k127_8052594_1	1031288.AXAA01000058_gene750	5.099e-32	130.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,36F5Z@31979|Clostridiaceae	186801|Clostridia	J	S-adenosylmethionine-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
WH2_k127_8058751_1	925409.KI911562_gene2780	2.173e-25	108.0	28M4Q@1|root,2ZAIK@2|Bacteria,4NJC3@976|Bacteroidetes,1IPH6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8058751_0	1239962.C943_03205	1.404e-222	714.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	dpp	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
WH2_k127_8061642_4	485916.Dtox_2843	1.47e-134	433.0	COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,24863@186801|Clostridia	186801|Clostridia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
WH2_k127_8061642_6	1268240.ATFI01000008_gene2516	2.339e-78	271.0	COG1218@1|root,COG1218@2|Bacteria,4NFHY@976|Bacteroidetes,2FP00@200643|Bacteroidia,4AMGH@815|Bacteroidaceae	976|Bacteroidetes	P	3'(2'),5'-bisphosphate nucleotidase	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
WH2_k127_8061642_5	1313301.AUGC01000007_gene609	1.002e-114	383.0	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes	976|Bacteroidetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
WH2_k127_8061642_0	1123277.KB893174_gene5915	3.386e-262	842.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,47JC0@768503|Cytophagia	976|Bacteroidetes	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
WH2_k127_8061642_8	391596.PBAL39_12322	6.466e-18	91.0	29AZZ@1|root,2ZXYX@2|Bacteria,4NP6M@976|Bacteroidetes,1ITA8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8061642_9	269798.CHU_3841	4.038e-10	68.0	COG2010@1|root,COG2010@2|Bacteria,4NSUK@976|Bacteroidetes,47R5S@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,SirB
WH2_k127_8061642_3	1501391.LG35_05415	3.261e-164	526.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,2FM9T@200643|Bacteroidia,22U3K@171550|Rikenellaceae	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
WH2_k127_8061642_2	1380384.JADN01000004_gene2029	1.241e-188	615.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HX1V@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
WH2_k127_8061642_7	1089547.KB913013_gene4561	6.999e-43	182.0	COG1404@1|root,COG3209@1|root,COG3391@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,4NPFV@976|Bacteroidetes	976|Bacteroidetes	MO	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8061642_1	761193.Runsl_4744	6.449e-218	714.0	COG0383@1|root,COG0383@2|Bacteria,4NEC3@976|Bacteroidetes,47NE0@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 38 C-terminal domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Glyco_hydro_38,Glyco_hydro_38C
WH2_k127_8085010_1	926562.Oweho_1669	7.527e-185	599.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1HWT7@117743|Flavobacteriia,2PAAK@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WH2_k127_8085010_0	984262.SGRA_1727	1.237e-209	659.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,1IQ5C@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	tuaD	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WH2_k127_8085010_2	1124780.ANNU01000005_gene2419	8.338e-81	273.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,47KX7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
WH2_k127_8086211_1	1120968.AUBX01000009_gene305	5.876e-47	171.0	COG1704@1|root,COG1704@2|Bacteria,4NMP9@976|Bacteroidetes,47V0B@768503|Cytophagia	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
WH2_k127_8086211_0	1120968.AUBX01000009_gene304	4.297e-136	455.0	COG4907@1|root,COG4907@2|Bacteria,4NJKC@976|Bacteroidetes	976|Bacteroidetes	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
WH2_k127_809795_3	1042376.AFPK01000032_gene1632	7.693e-11	63.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,1I34F@117743|Flavobacteriia,4078T@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
WH2_k127_809795_1	1408433.JHXV01000012_gene3999	2e-63	237.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY0A@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
WH2_k127_809795_4	1123277.KB893228_gene2008	2.493e-08	65.0	COG2885@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,4NGEP@976|Bacteroidetes,47NK0@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
WH2_k127_809795_0	700598.Niako_1031	4.324e-77	269.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,1IS23@117747|Sphingobacteriia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
WH2_k127_809795_2	1550091.JROE01000006_gene2643	1.911e-45	167.0	COG0270@1|root,COG0270@2|Bacteria,4NG9A@976|Bacteroidetes,1IR0T@117747|Sphingobacteriia	976|Bacteroidetes	H	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
WH2_k127_8113711_0	984262.SGRA_2537	4.246e-197	639.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes	976|Bacteroidetes	DZ	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
WH2_k127_8113711_1	1227739.Hsw_3426	2.115e-168	551.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
WH2_k127_8133274_0	589865.DaAHT2_2072	7.523e-286	895.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2MHPT@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Elongation factor Tu domain 2	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WH2_k127_8133274_1	1046627.BZARG_2053	1.142e-79	289.0	COG0644@1|root,COG0644@2|Bacteria,4NEI6@976|Bacteroidetes,1HYZB@117743|Flavobacteriia	976|Bacteroidetes	C	pyridine nucleotide-disulfide oxidoreductase	fixC	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
WH2_k127_8136808_1	1008457.BAEX01000001_gene1183	4.421e-96	321.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1HWY5@117743|Flavobacteriia,47H4R@76831|Myroides	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
WH2_k127_8136808_0	1123277.KB893181_gene2326	1.384e-172	555.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,47JT3@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WH2_k127_8164700_1	1313301.AUGC01000001_gene1771	5.376e-57	202.0	2CC29@1|root,32RUM@2|Bacteria,4NS83@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
WH2_k127_8164700_2	713586.KB900536_gene104	1.401e-31	128.0	COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,1WZ0Y@135613|Chromatiales	135613|Chromatiales	S	small membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
WH2_k127_8164700_0	1408433.JHXV01000010_gene567	1.301e-258	806.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1HX6C@117743|Flavobacteriia,2PA7A@246874|Cryomorphaceae	976|Bacteroidetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
WH2_k127_8164700_3	1094466.KQS_05720	2.69e-06	60.0	COG0793@1|root,COG0793@2|Bacteria,4NGGJ@976|Bacteroidetes,1HY6W@117743|Flavobacteriia,2NS7E@237|Flavobacterium	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
WH2_k127_8168297_2	1408433.JHXV01000002_gene455	2.73e-103	343.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,1HY5P@117743|Flavobacteriia,2PAN0@246874|Cryomorphaceae	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
WH2_k127_8168297_3	761193.Runsl_2694	3.742e-54	196.0	COG0457@1|root,COG0457@2|Bacteria,4NRIH@976|Bacteroidetes,47QEH@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
WH2_k127_8168297_1	1392490.JHZX01000001_gene3440	1.309e-119	394.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1HWJD@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
WH2_k127_8168297_0	755732.Fluta_0268	7.199e-199	631.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1HXC5@117743|Flavobacteriia,2PAKV@246874|Cryomorphaceae	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
WH2_k127_8182432_0	880073.Calab_2100	5.34e-149	492.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
WH2_k127_8182432_1	929562.Emtol_3010	1.509e-23	105.0	COG0823@1|root,COG1361@1|root,COG2373@1|root,COG0823@2|Bacteria,COG1361@2|Bacteria,COG2373@2|Bacteria,4PPBJ@976|Bacteroidetes,47TYA@768503|Cytophagia	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8189785_0	1144275.COCOR_05233	8.892e-43	173.0	COG2849@1|root,COG2849@2|Bacteria,1NMUU@1224|Proteobacteria,432BU@68525|delta/epsilon subdivisions,2WT7D@28221|Deltaproteobacteria,2Z2M9@29|Myxococcales	28221|Deltaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
WH2_k127_8189785_1	761193.Runsl_4744	3.667e-05	52.0	COG0383@1|root,COG0383@2|Bacteria,4NEC3@976|Bacteroidetes,47NE0@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 38 C-terminal domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Glyco_hydro_38,Glyco_hydro_38C
WH2_k127_8195034_3	1173024.KI912149_gene6079	2.424e-51	186.0	COG1045@1|root,COG1045@2|Bacteria,1GHYE@1117|Cyanobacteria,1JINP@1189|Stigonemataceae	1117|Cyanobacteria	E	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
WH2_k127_8195034_0	504472.Slin_4349	1.753e-79	298.0	COG2010@1|root,COG3291@1|root,COG4625@1|root,COG2010@2|Bacteria,COG3291@2|Bacteria,COG4625@2|Bacteria,4NJDV@976|Bacteroidetes,47NUN@768503|Cytophagia	976|Bacteroidetes	E	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin,NPCBM,PA14,RicinB_lectin_2
WH2_k127_8195034_2	762968.HMPREF9441_00402	1.01e-65	241.0	COG0438@1|root,COG0438@2|Bacteria,4NGSA@976|Bacteroidetes,2FPXN@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WH2_k127_8195034_1	762982.HMPREF9442_02458	1.364e-74	263.0	COG0451@1|root,COG0451@2|Bacteria,4PHT4@976|Bacteroidetes,2FNQG@200643|Bacteroidia	976|Bacteroidetes	M	COG0451 Nucleoside-diphosphate-sugar	-	-	5.1.3.26	ko:K19997	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
WH2_k127_8195034_4	1356852.N008_01575	1.501e-17	87.0	COG1922@1|root,COG1922@2|Bacteria,4NJGT@976|Bacteroidetes,47NEK@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the glycosyltransferase 26 family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
WH2_k127_8221237_0	1123234.AUKI01000011_gene1164	9.416e-146	471.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,1HYME@117743|Flavobacteriia	976|Bacteroidetes	Q	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
WH2_k127_8221237_1	1380394.JADL01000003_gene5127	1.961e-12	77.0	COG1266@1|root,COG1266@2|Bacteria,1QPQ0@1224|Proteobacteria	1224|Proteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WH2_k127_8260580_1	1408473.JHXO01000016_gene1934	2.567e-78	273.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,2FR8P@200643|Bacteroidia	976|Bacteroidetes	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
WH2_k127_8260580_0	1408473.JHXO01000016_gene1933	9.353e-99	327.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,2FT12@200643|Bacteroidia	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
WH2_k127_8260580_2	886379.AEWI01000013_gene2120	5.484e-72	248.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,2FMR9@200643|Bacteroidia,3XKJP@558415|Marinilabiliaceae	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH2_k127_8278266_0	1408433.JHXV01000009_gene1250	8.998e-63	235.0	COG4935@1|root,COG4935@2|Bacteria,4PP7N@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8280175_4	1123276.KB893265_gene4485	1.328e-24	109.0	COG2386@1|root,COG2386@2|Bacteria,4NFQV@976|Bacteroidetes,47K0P@768503|Cytophagia	976|Bacteroidetes	O	ABC-type transport system involved in cytochrome c biogenesis permease component	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
WH2_k127_8280175_3	385682.AFSL01000082_gene1201	1.01e-52	193.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,2FQY1@200643|Bacteroidia,3XK2G@558415|Marinilabiliaceae	976|Bacteroidetes	O	Glutathione peroxidase	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
WH2_k127_8280175_1	1453500.AT05_06720	1.584e-54	199.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,1I1AR@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
WH2_k127_8280175_0	388413.ALPR1_12350	6.078e-78	274.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,47K51@768503|Cytophagia	976|Bacteroidetes	S	PFAM GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
WH2_k127_8280175_2	1356852.N008_10585	1.23e-53	203.0	COG2244@1|root,COG2244@2|Bacteria,4NRKF@976|Bacteroidetes,47XRY@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
WH2_k127_8286417_2	497321.C664_10448	8.345e-27	109.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,2KUBF@206389|Rhodocyclales	206389|Rhodocyclales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
WH2_k127_8286417_0	497321.C664_10448	8.001e-245	756.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,2KUBF@206389|Rhodocyclales	206389|Rhodocyclales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
WH2_k127_8286417_1	497321.C664_10443	1.325e-45	177.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,2KUIS@206389|Rhodocyclales	206389|Rhodocyclales	P	Cytochrome C1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
WH2_k127_8288565_1	1227739.Hsw_2474	2.845e-53	193.0	COG0497@1|root,COG0497@2|Bacteria,4PMJC@976|Bacteroidetes,47YHC@768503|Cytophagia	976|Bacteroidetes	L	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
WH2_k127_8288565_0	1122165.AUHS01000047_gene3184	6.984e-54	205.0	COG1520@1|root,COG1520@2|Bacteria,1RBUT@1224|Proteobacteria,1S27R@1236|Gammaproteobacteria,1JEPR@118969|Legionellales	118969|Legionellales	DZ	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
WH2_k127_8290894_0	1453500.AT05_07935	4.04e-245	782.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1HWVA@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
WH2_k127_8290894_1	1358423.N180_14760	9.849e-99	329.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1IPRJ@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
WH2_k127_8290894_3	1408433.JHXV01000001_gene693	1.493e-48	190.0	COG3637@1|root,COG3637@2|Bacteria,4NUEN@976|Bacteroidetes,1IC3X@117743|Flavobacteriia,2PB1K@246874|Cryomorphaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
WH2_k127_8290894_2	1408813.AYMG01000028_gene2429	1.245e-70	250.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,1IPBF@117747|Sphingobacteriia	976|Bacteroidetes	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
WH2_k127_8290894_4	1121373.KB903643_gene3493	1.403e-32	136.0	COG4775@1|root,COG4775@2|Bacteria,4NF9Y@976|Bacteroidetes,47KUK@768503|Cytophagia	976|Bacteroidetes	M	PFAM surface antigen variable number repeat	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
WH2_k127_8316778_0	321327.CYA_2836	1.398e-37	160.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1GYFK@1129|Synechococcus	1117|Cyanobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WH2_k127_8328762_2	1137281.D778_01983	5.077e-14	73.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HZ6V@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH2_k127_8328762_0	485918.Cpin_6846	2.74e-75	270.0	COG0842@1|root,COG0842@2|Bacteria,4NGFA@976|Bacteroidetes,1ISKA@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WH2_k127_8328762_1	641526.ADIWIN_3884	8.138e-16	91.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,1HY14@117743|Flavobacteriia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WH2_k127_8336067_2	908612.HMPREF9720_1311	5.69e-18	85.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,2FMCF@200643|Bacteroidia,22UX6@171550|Rikenellaceae	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
WH2_k127_8336067_3	714943.Mucpa_5486	1.586e-13	79.0	COG0596@1|root,COG0596@2|Bacteria,4PKKR@976|Bacteroidetes,1ITSI@117747|Sphingobacteriia	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,UPF0227
WH2_k127_8336067_4	313596.RB2501_00306	4.116e-05	48.0	COG0596@1|root,COG0596@2|Bacteria,4PKKR@976|Bacteroidetes,1IJBZ@117743|Flavobacteriia	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,UPF0227
WH2_k127_8336067_1	649349.Lbys_3214	8.993e-25	115.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,47XHA@768503|Cytophagia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WH2_k127_8336067_0	700598.Niako_5588	7.978e-77	269.0	COG0861@1|root,COG0861@2|Bacteria,4NH6F@976|Bacteroidetes,1J0BP@117747|Sphingobacteriia	976|Bacteroidetes	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
WH2_k127_8374535_0	755732.Fluta_2899	1.135e-36	154.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2PBEH@246874|Cryomorphaceae	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
WH2_k127_8379922_0	309807.SRU_0483	7.196e-79	288.0	COG0642@1|root,COG0784@1|root,COG3292@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Reg_prop,Response_reg,Y_Y_Y
WH2_k127_8396994_0	153721.MYP_3800	1.337e-229	733.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,47MF3@768503|Cytophagia	976|Bacteroidetes	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
WH2_k127_8396994_1	1237149.C900_04437	9.182e-11	70.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	2.8.1.1,2.8.1.2	ko:K01011,ko:K06867	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5,Rhodanese
WH2_k127_8402494_2	385682.AFSL01000001_gene1997	5.561e-70	248.0	COG0438@1|root,COG0438@2|Bacteria,4NJ1W@976|Bacteroidetes,2FTR3@200643|Bacteroidia,3XK2C@558415|Marinilabiliaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WH2_k127_8402494_1	1123248.KB893386_gene1892	5.498e-86	299.0	COG3081@1|root,COG3081@2|Bacteria,4NFSN@976|Bacteroidetes,1IPSX@117747|Sphingobacteriia	976|Bacteroidetes	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
WH2_k127_8402494_0	504472.Slin_5717	1.24e-99	334.0	COG0451@1|root,COG0451@2|Bacteria,4NG8Y@976|Bacteroidetes,47N8X@768503|Cytophagia	976|Bacteroidetes	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
WH2_k127_8402494_3	1301100.HG529374_gene1510	7.631e-16	80.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,247XP@186801|Clostridia,36DCC@31979|Clostridiaceae	186801|Clostridia	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
WH2_k127_8413102_2	1346330.M472_11525	9.157e-24	104.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes	976|Bacteroidetes	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
WH2_k127_8413102_1	82654.Pse7367_2268	1.203e-53	199.0	COG1443@1|root,COG1443@2|Bacteria,1GDFS@1117|Cyanobacteria	1117|Cyanobacteria	I	NUDIX domain	-	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
WH2_k127_8413102_0	1123276.KB893257_gene2731	1.021e-91	306.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,47J9F@768503|Cytophagia	976|Bacteroidetes	I	PFAM Squalene phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
WH2_k127_842134_0	1408433.JHXV01000001_gene1087	5.298e-96	319.0	COG0046@1|root,COG0046@2|Bacteria,4NETY@976|Bacteroidetes,1HYI9@117743|Flavobacteriia,2PB53@246874|Cryomorphaceae	976|Bacteroidetes	F	involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
WH2_k127_842134_3	269798.CHU_3537	1.186e-41	159.0	COG2077@1|root,COG2077@2|Bacteria,4NNGR@976|Bacteroidetes,47RNU@768503|Cytophagia	976|Bacteroidetes	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
WH2_k127_842134_4	504472.Slin_3656	3.257e-36	145.0	COG1595@1|root,COG1595@2|Bacteria,4NSVA@976|Bacteroidetes,47QAU@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH2_k127_842134_5	714943.Mucpa_2724	1.992e-13	77.0	2EFPT@1|root,339FT@2|Bacteria,4NV1V@976|Bacteroidetes,1IU65@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_842134_1	1239962.C943_03473	1.671e-65	233.0	COG0744@1|root,COG0744@2|Bacteria,4NF90@976|Bacteroidetes,47MHF@768503|Cytophagia	976|Bacteroidetes	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
WH2_k127_842134_2	1122176.KB903540_gene76	3.936e-50	187.0	COG1028@1|root,COG1028@2|Bacteria,4PKBF@976|Bacteroidetes,1J0YN@117747|Sphingobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WH2_k127_8430812_0	1121904.ARBP01000072_gene282	4.259e-99	342.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WH2_k127_8430812_1	1163409.UUA_13170	0.0006811	46.0	COG1846@1|root,COG1846@2|Bacteria,1N7BV@1224|Proteobacteria,1SB03@1236|Gammaproteobacteria,1X743@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
WH2_k127_8439268_0	1168289.AJKI01000025_gene1464	6.123e-181	579.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,2FNFZ@200643|Bacteroidia,3XJ9Y@558415|Marinilabiliaceae	976|Bacteroidetes	L	ABC transporter	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
WH2_k127_8444543_0	926562.Oweho_0143	7.393e-47	181.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,1HXI1@117743|Flavobacteriia,2PAM4@246874|Cryomorphaceae	976|Bacteroidetes	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
WH2_k127_8444543_1	1296415.JACC01000010_gene2202	1.221e-28	126.0	COG0760@1|root,COG0760@2|Bacteria,4NG2P@976|Bacteroidetes,1HX2I@117743|Flavobacteriia,2YGQ0@290174|Aquimarina	976|Bacteroidetes	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
WH2_k127_8444543_2	926562.Oweho_0145	9.26e-10	63.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1HXTE@117743|Flavobacteriia,2PA5V@246874|Cryomorphaceae	976|Bacteroidetes	M	PPIC-type PPIASE domain	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
WH2_k127_8447293_0	926556.Echvi_1565	7.82e-62	236.0	COG0168@1|root,COG0168@2|Bacteria,4NF7R@976|Bacteroidetes,47JIP@768503|Cytophagia	976|Bacteroidetes	P	PFAM Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
WH2_k127_8447293_1	927658.AJUM01000037_gene2023	1.264e-28	134.0	COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,2FQ6V@200643|Bacteroidia,3XJUS@558415|Marinilabiliaceae	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
WH2_k127_8472533_0	525373.HMPREF0766_10790	1.201e-67	240.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,1IPUQ@117747|Sphingobacteriia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
WH2_k127_8472533_1	1380384.JADN01000006_gene2417	3.834e-57	206.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,1I19W@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
WH2_k127_8472533_2	1168034.FH5T_00060	1.591e-17	89.0	2E8SV@1|root,3333M@2|Bacteria,4NSHV@976|Bacteroidetes,2FV1F@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4293
WH2_k127_8502645_1	78245.Xaut_3514	1.586e-98	324.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2TQSB@28211|Alphaproteobacteria,3EYIW@335928|Xanthobacteraceae	28211|Alphaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
WH2_k127_8502645_0	1223410.KN050846_gene285	5.428e-118	400.0	COG3291@1|root,COG3291@2|Bacteria,4PKMZ@976|Bacteroidetes,1I9DA@117743|Flavobacteriia	976|Bacteroidetes	S	TIGRFAM Por secretion system C-terminal sorting domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8502645_3	460265.Mnod_0699	6.042e-13	82.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2TQSB@28211|Alphaproteobacteria,1JQTV@119045|Methylobacteriaceae	28211|Alphaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
WH2_k127_8502645_2	925409.KI911562_gene2130	4.655e-73	256.0	COG0038@1|root,COG0038@2|Bacteria,4NFCF@976|Bacteroidetes,1IUVQ@117747|Sphingobacteriia	976|Bacteroidetes	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	TrkA_C,Voltage_CLC
WH2_k127_8503388_0	1408433.JHXV01000021_gene1648	1.371e-235	739.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1HWKZ@117743|Flavobacteriia,2PA6N@246874|Cryomorphaceae	976|Bacteroidetes	S	Glutamine synthetase type III N terminal	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
WH2_k127_8503388_2	1408473.JHXO01000006_gene1037	2.361e-133	454.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,2FPQX@200643|Bacteroidia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
WH2_k127_8503388_1	203275.BFO_1374	2.525e-183	580.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,2FM0G@200643|Bacteroidia,22VWI@171551|Porphyromonadaceae	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WH2_k127_8509909_1	761193.Runsl_1666	2.998e-92	306.0	COG1216@1|root,COG1216@2|Bacteria,4PNB1@976|Bacteroidetes,47KU6@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH2_k127_8509909_0	760192.Halhy_6511	1.181e-141	475.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,1IUX1@117747|Sphingobacteriia	976|Bacteroidetes	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WH2_k127_8509909_2	1185876.BN8_04640	3.364e-54	196.0	COG0626@1|root,COG0626@2|Bacteria,4NH38@976|Bacteroidetes,47K5I@768503|Cytophagia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
WH2_k127_8511087_0	1137281.D778_01913	8.124e-68	242.0	COG0739@1|root,COG0739@2|Bacteria,4NIH1@976|Bacteroidetes,1HZT8@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WH2_k127_8511087_1	1123277.KB893191_gene2898	5.343e-46	178.0	COG0823@1|root,COG5492@1|root,COG0823@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,PD40,Pkinase
WH2_k127_8523547_0	391596.PBAL39_07115	8.939e-162	529.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1IPW0@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
WH2_k127_8523547_1	468059.AUHA01000003_gene1874	2.238e-07	53.0	COG3000@1|root,COG3000@2|Bacteria,4NFWX@976|Bacteroidetes,1IPCD@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
WH2_k127_8549852_0	313606.M23134_02237	7.857e-158	527.0	COG3209@1|root,COG3291@1|root,COG3386@1|root,COG4932@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,4NJ9V@976|Bacteroidetes,47N8F@768503|Cytophagia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
WH2_k127_8560095_4	1123035.ARLA01000019_gene2645	2.354e-05	48.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia,4C2D7@83612|Psychroflexus	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
WH2_k127_8560095_3	1349785.BAUG01000002_gene123	6.539e-06	57.0	2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia	976|Bacteroidetes	S	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
WH2_k127_8560095_2	1158292.JPOE01000005_gene1019	3.174e-13	72.0	COG2020@1|root,COG2020@2|Bacteria,1NAP9@1224|Proteobacteria,2VVTA@28216|Betaproteobacteria,1KNVV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
WH2_k127_8560095_0	755732.Fluta_0946	2.578e-148	475.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HXA1@117743|Flavobacteriia,2PA5W@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WH2_k127_8560095_1	926562.Oweho_0145	4.26e-88	302.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1HXTE@117743|Flavobacteriia,2PA5V@246874|Cryomorphaceae	976|Bacteroidetes	M	PPIC-type PPIASE domain	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
WH2_k127_8561560_0	926562.Oweho_0762	2.246e-64	242.0	COG1983@1|root,COG3256@1|root,COG1983@2|Bacteria,COG3256@2|Bacteria,4NG3T@976|Bacteroidetes,1HX01@117743|Flavobacteriia,2PAXN@246874|Cryomorphaceae	976|Bacteroidetes	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
WH2_k127_8561560_1	1392489.JPOL01000002_gene991	2.079e-46	169.0	COG1695@1|root,COG1695@2|Bacteria,4NSI4@976|Bacteroidetes,1I2SA@117743|Flavobacteriia,2XK81@283735|Leeuwenhoekiella	976|Bacteroidetes	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
WH2_k127_856427_2	886379.AEWI01000002_gene475	1.237e-56	206.0	COG0512@1|root,COG0512@2|Bacteria,4NE4I@976|Bacteroidetes,2FM5F@200643|Bacteroidia,3XJ03@558415|Marinilabiliaceae	976|Bacteroidetes	EH	Peptidase C26	pabA	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
WH2_k127_856427_0	1408473.JHXO01000009_gene3352	4.638e-165	552.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,2FM9F@200643|Bacteroidia	976|Bacteroidetes	M	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_856427_1	926562.Oweho_0210	3.818e-90	316.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,1HX7G@117743|Flavobacteriia,2PAR3@246874|Cryomorphaceae	976|Bacteroidetes	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
WH2_k127_856427_3	1121094.KB894643_gene1914	5.378e-11	67.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,2FPK9@200643|Bacteroidia,4AM1J@815|Bacteroidaceae	976|Bacteroidetes	Q	COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
WH2_k127_8570002_1	867900.Celly_2033	4.2e-19	96.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,1I50Z@117743|Flavobacteriia	976|Bacteroidetes	K	cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WH2_k127_8570002_0	926549.KI421517_gene2007	2.238e-122	413.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH2_k127_8578137_0	1123035.ARLA01000023_gene1188	3.231e-318	990.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1HY80@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WH2_k127_8578137_1	391598.FBBAL38_09857	2.839e-44	185.0	2DBBI@1|root,2Z888@2|Bacteria,4NQB6@976|Bacteroidetes,1I62S@117743|Flavobacteriia	976|Bacteroidetes	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	YHYH
WH2_k127_858015_4	926562.Oweho_1215	2.731e-23	101.0	COG0236@1|root,COG0236@2|Bacteria,4NV57@976|Bacteroidetes,1I568@117743|Flavobacteriia,2PB5Z@246874|Cryomorphaceae	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	acpP_2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
WH2_k127_858015_1	153721.MYP_4253	1.49e-64	233.0	COG4261@1|root,COG4261@2|Bacteria,4NF49@976|Bacteroidetes,47PF5@768503|Cytophagia	976|Bacteroidetes	S	Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
WH2_k127_858015_5	1122605.KB893647_gene250	3.581e-23	109.0	COG4706@1|root,COG4706@2|Bacteria,4NSB5@976|Bacteroidetes,1IU4J@117747|Sphingobacteriia	976|Bacteroidetes	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_858015_2	1270193.JARP01000002_gene592	5.045e-37	143.0	COG0824@1|root,COG0824@2|Bacteria,4NRHH@976|Bacteroidetes,1I3DP@117743|Flavobacteriia,2NUM0@237|Flavobacterium	976|Bacteroidetes	S	thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
WH2_k127_858015_0	926562.Oweho_1219	8.305e-85	299.0	COG0304@1|root,COG0304@2|Bacteria,4NE8K@976|Bacteroidetes,1HXWZ@117743|Flavobacteriia,2PAQ2@246874|Cryomorphaceae	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabF2	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WH2_k127_858015_7	1346330.M472_06815	6.043e-17	89.0	COG0304@1|root,COG0304@2|Bacteria,4NMSI@976|Bacteroidetes,1ITHW@117747|Sphingobacteriia	976|Bacteroidetes	IQ	3-oxoacyl-ACP synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_858015_3	1046627.BZARG_2034	2.899e-25	115.0	COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes,1I3W1@117743|Flavobacteriia	976|Bacteroidetes	IQ	acyl carrier protein	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
WH2_k127_858015_6	1122986.KB908327_gene467	2.107e-18	91.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,2FPUI@200643|Bacteroidia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WH2_k127_8585929_0	1123278.KB893499_gene398	2.829e-84	288.0	COG1526@1|root,COG1526@2|Bacteria,4NFJB@976|Bacteroidetes,47MUW@768503|Cytophagia	976|Bacteroidetes	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
WH2_k127_8585929_1	1123393.KB891316_gene1541	1.388e-67	234.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2VQC5@28216|Betaproteobacteria	28216|Betaproteobacteria	L	glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
WH2_k127_8626854_0	926549.KI421517_gene554	4.324e-159	527.0	COG4447@1|root,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,47N4Z@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig
WH2_k127_8632412_0	946077.W5A_01135	7.43e-193	609.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1HY5U@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WH2_k127_8632412_5	1121912.AUHD01000016_gene2918	1.108e-14	85.0	2C34A@1|root,2ZBS9@2|Bacteria,4NM9S@976|Bacteroidetes,1I1KR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8632412_4	755732.Fluta_1472	5.144e-20	93.0	COG0721@1|root,COG0721@2|Bacteria,4NV0A@976|Bacteroidetes,1IBR4@117743|Flavobacteriia,2PB5V@246874|Cryomorphaceae	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
WH2_k127_8632412_3	1408433.JHXV01000016_gene1862	1.669e-45	175.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,1HXST@117743|Flavobacteriia,2PB5B@246874|Cryomorphaceae	976|Bacteroidetes	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WH2_k127_8632412_1	755732.Fluta_1474	4.37e-127	431.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,1HY8G@117743|Flavobacteriia,2PAFI@246874|Cryomorphaceae	976|Bacteroidetes	J	PFAM tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
WH2_k127_8632412_2	504472.Slin_5447	1.752e-108	358.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,47JQT@768503|Cytophagia	976|Bacteroidetes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
WH2_k127_865001_0	929562.Emtol_2379	2.405e-100	338.0	COG2070@1|root,COG2070@2|Bacteria,4NEGW@976|Bacteroidetes,47JXU@768503|Cytophagia	976|Bacteroidetes	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_865001_1	886377.Murru_2903	1.878e-68	241.0	COG3256@1|root,COG3256@2|Bacteria,4NG9H@976|Bacteroidetes,1HZ9Q@117743|Flavobacteriia	976|Bacteroidetes	P	nitric oxide reductase	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
WH2_k127_8655987_0	1123277.KB893190_gene4927	7.817e-62	219.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,47JCK@768503|Cytophagia	976|Bacteroidetes	CP	COGs COG1668 ABC-type Na efflux pump permease component	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WH2_k127_8655987_1	1168289.AJKI01000011_gene569	8.325e-57	210.0	COG0248@1|root,COG0248@2|Bacteria,4NEI0@976|Bacteroidetes,2FN6C@200643|Bacteroidia,3XJF5@558415|Marinilabiliaceae	976|Bacteroidetes	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
WH2_k127_8655987_2	688270.Celal_1042	1.782e-08	63.0	COG1284@1|root,COG1284@2|Bacteria,4NG9F@976|Bacteroidetes,1HY56@117743|Flavobacteriia,1F9YR@104264|Cellulophaga	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
WH2_k127_8660598_0	1121904.ARBP01000002_gene6983	1.577e-149	498.0	COG4206@1|root,COG4206@2|Bacteria,4PKF2@976|Bacteroidetes,47JDS@768503|Cytophagia	976|Bacteroidetes	H	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WH2_k127_8661216_1	1453500.AT05_03545	1.417e-21	95.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1HXGV@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
WH2_k127_8661216_0	1178825.ALIH01000009_gene1342	4.267e-99	332.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1HX6V@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
WH2_k127_8687789_0	1239962.C943_04225	1.632e-219	694.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,4NGF6@976|Bacteroidetes,47NEG@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefC	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
WH2_k127_8697758_0	926562.Oweho_1527	1.193e-24	116.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,Laminin_G_3,MAM,Malectin,PKD,fn3
WH2_k127_8697758_1	926562.Oweho_1527	2.245e-13	83.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,Laminin_G_3,MAM,Malectin,PKD,fn3
WH2_k127_8698753_0	941449.dsx2_0368	1.011e-157	510.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,42MIR@68525|delta/epsilon subdivisions,2WJ85@28221|Deltaproteobacteria,2M8UI@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM membrane bound O-acyl transferase MBOAT	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
WH2_k127_8698753_2	362418.IW19_17700	4.518e-06	54.0	COG2849@1|root,COG2849@2|Bacteria,4NS8U@976|Bacteroidetes,1I41J@117743|Flavobacteriia,2NX3I@237|Flavobacterium	976|Bacteroidetes	S	Membrane-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
WH2_k127_8698753_1	1280949.HAD_05660	4.95e-36	142.0	COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,2U78G@28211|Alphaproteobacteria,43XUJ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	dioxygenase of extradiol dioxygenase family	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
WH2_k127_8701967_2	1125863.JAFN01000001_gene1812	0.00048	51.0	COG1520@1|root,COG2931@1|root,COG3291@1|root,COG3386@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,1N8Z7@1224|Proteobacteria,43AIY@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	heme-binding sites	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_C1
WH2_k127_8701967_1	1124780.ANNU01000024_gene3045	0.0001261	53.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NF1M@976|Bacteroidetes,47NC9@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
WH2_k127_8701967_0	1408433.JHXV01000029_gene3117	2.894e-39	163.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4
WH2_k127_872174_1	926562.Oweho_1523	1.151e-47	177.0	COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,1HWVY@117743|Flavobacteriia,2PAAA@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Alanine dehydrogenase PNT, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
WH2_k127_872174_2	1408433.JHXV01000010_gene535	1.353e-13	78.0	2AAU0@1|root,30Y70@2|Bacteria,4PBYC@976|Bacteroidetes,1ICQX@117743|Flavobacteriia,2PBTU@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_872174_0	1121957.ATVL01000012_gene817	1.815e-54	213.0	COG1404@1|root,COG3291@1|root,COG4733@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4NHDH@976|Bacteroidetes,47YQJ@768503|Cytophagia	976|Bacteroidetes	O	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M9,Peptidase_M9_N
WH2_k127_8747154_1	867902.Ornrh_2310	3.167e-90	310.0	COG0038@1|root,COG0038@2|Bacteria,4NFCF@976|Bacteroidetes,1HWJE@117743|Flavobacteriia	976|Bacteroidetes	P	Chloride channel protein	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	TrkA_C,Voltage_CLC
WH2_k127_8747154_0	1348583.ATLH01000029_gene1248	4.383e-178	567.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1HY0T@117743|Flavobacteriia,1F8EY@104264|Cellulophaga	976|Bacteroidetes	F	PFAM Na dependent nucleoside transporter, C-terminal	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
WH2_k127_8764440_1	755732.Fluta_2318	7.125e-28	117.0	COG3675@1|root,COG3675@2|Bacteria,4PKPE@976|Bacteroidetes,1IKDT@117743|Flavobacteriia,2PBG3@246874|Cryomorphaceae	976|Bacteroidetes	I	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
WH2_k127_8764440_4	1267005.KB911257_gene744	0.0009869	49.0	2A6BG@1|root,30V48@2|Bacteria,1R87F@1224|Proteobacteria,2U1PB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8764440_3	269798.CHU_0740	8.431e-11	72.0	2C85E@1|root,30YA3@2|Bacteria,4PC1M@976|Bacteroidetes,47WP9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8764440_0	1121904.ARBP01000017_gene5123	4.146e-60	223.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	DLH
WH2_k127_8764440_2	1121875.KB907549_gene1916	7.843e-12	67.0	COG3503@1|root,COG3503@2|Bacteria,4NFAF@976|Bacteroidetes,1HX24@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
WH2_k127_8782977_2	1408433.JHXV01000014_gene3650	3.47e-109	369.0	COG3474@1|root,COG3474@2|Bacteria,4PKQA@976|Bacteroidetes,1I8RP@117743|Flavobacteriia,2PAPE@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
WH2_k127_8782977_0	1408433.JHXV01000014_gene3651	0.0	1040.0	COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1HWY0@117743|Flavobacteriia,2PA5H@246874|Cryomorphaceae	976|Bacteroidetes	C	4Fe-4S dicluster domain	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
WH2_k127_8782977_1	755732.Fluta_1182	2.424e-152	485.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia,2PABZ@246874|Cryomorphaceae	976|Bacteroidetes	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
WH2_k127_8788131_2	56107.Cylst_3960	3.452e-14	75.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HR5M@1161|Nostocales	1117|Cyanobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
WH2_k127_8788131_1	1463856.JOHY01000001_gene374	1.103e-26	120.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	2.7.8.7	ko:K00997,ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
WH2_k127_8788131_0	1122621.ATZA01000029_gene2765	5.574e-115	388.0	COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,1IQPT@117747|Sphingobacteriia	976|Bacteroidetes	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD2_2	-	3.1.11.5	ko:K01144	-	-	-	-	ko00000,ko01000	-	-	-	AAA_30,UvrD_C_2
WH2_k127_8793562_2	1122176.KB903566_gene3496	7.86e-24	119.0	COG3210@1|root,COG3291@1|root,COG4932@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,4PHJX@976|Bacteroidetes,1IW6U@117747|Sphingobacteriia	976|Bacteroidetes	MU	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
WH2_k127_8793562_1	529818.AMSG_12242T0	1.032e-26	128.0	29QRV@1|root,2RX97@2759|Eukaryota	2759|Eukaryota	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
WH2_k127_8793562_3	926562.Oweho_0540	6.148e-20	106.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WH2_k127_8793562_0	1408433.JHXV01000005_gene2349	1.357e-146	488.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia,2PBIN@246874|Cryomorphaceae	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
WH2_k127_8809873_0	742725.HMPREF9450_00969	5.246e-30	134.0	2AEW7@1|root,314TU@2|Bacteria,4PJ2P@976|Bacteroidetes,2FQPU@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8821788_0	755732.Fluta_0535	6.037e-44	176.0	COG1555@1|root,COG1555@2|Bacteria,4NE88@976|Bacteroidetes,1I7MT@117743|Flavobacteriia,2PAFS@246874|Cryomorphaceae	976|Bacteroidetes	L	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
WH2_k127_8821788_1	926562.Oweho_1820	6.027e-40	160.0	COG1555@1|root,COG1555@2|Bacteria,4NQC1@976|Bacteroidetes,1IBFS@117743|Flavobacteriia,2PB2U@246874|Cryomorphaceae	976|Bacteroidetes	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8838625_0	1453500.AT05_01165	1.1e-126	425.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,1HWWI@117743|Flavobacteriia	976|Bacteroidetes	G	Transketolase	dxs	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
WH2_k127_8838625_1	926562.Oweho_1341	3.113e-87	297.0	COG2304@1|root,COG2304@2|Bacteria,4NJF1@976|Bacteroidetes,1I5HE@117743|Flavobacteriia,2PAI7@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
WH2_k127_8839554_1	929556.Solca_3427	3.157e-19	87.0	COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,1IPGW@117747|Sphingobacteriia	976|Bacteroidetes	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
WH2_k127_8839554_0	1239962.C943_01556	2.128e-245	767.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,47MRY@768503|Cytophagia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
WH2_k127_8849412_0	1408473.JHXO01000013_gene620	9.195e-228	718.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes,2FMWT@200643|Bacteroidia	976|Bacteroidetes	E	Glutamate formimidoyltransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
WH2_k127_8849412_1	1279009.ADICEAN_00064	6.565e-137	464.0	COG1752@1|root,COG1752@2|Bacteria,4NF97@976|Bacteroidetes,47KND@768503|Cytophagia	976|Bacteroidetes	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
WH2_k127_8849412_5	883158.HMPREF9140_01326	3.161e-31	134.0	COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,2FNFM@200643|Bacteroidia	976|Bacteroidetes	G	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
WH2_k127_8849412_3	1408433.JHXV01000018_gene3846	2.608e-55	201.0	COG2197@1|root,COG2197@2|Bacteria,4NNVV@976|Bacteroidetes,1ICPE@117743|Flavobacteriia,2PBHR@246874|Cryomorphaceae	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
WH2_k127_8849412_2	1121094.KB894643_gene1696	1.664e-83	287.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,2FM13@200643|Bacteroidia,4AMDA@815|Bacteroidaceae	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
WH2_k127_8849412_7	518766.Rmar_0284	1.069e-09	68.0	COG1404@1|root,COG3867@1|root,COG1404@2|Bacteria,COG3867@2|Bacteria	2|Bacteria	G	arabinogalactan endo-1,4-beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,DUF4397,F5_F8_type_C,Glyco_hydro_53,He_PIG,Mucin_bdg,RicinB_lectin_2,SLH
WH2_k127_8849412_4	926549.KI421517_gene1342	1.008e-33	138.0	COG1366@1|root,COG1366@2|Bacteria,4NTPB@976|Bacteroidetes,47R1F@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
WH2_k127_8849412_6	1538644.KO02_19475	4.356e-29	118.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,1IP8Y@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WH2_k127_8851646_1	313596.RB2501_06115	7.446e-39	151.0	arCOG10456@1|root,2ZA6T@2|Bacteria,4NGZ2@976|Bacteroidetes,1HXIA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8851646_0	1313421.JHBV01000019_gene5329	2.857e-66	245.0	COG2132@1|root,COG4935@1|root,COG2132@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	CHU_C,Copper-bind,Cu-oxidase_3,SprB
WH2_k127_8851990_1	1408473.JHXO01000010_gene3515	6.218e-14	80.0	COG4775@1|root,COG4775@2|Bacteria,4NFFZ@976|Bacteroidetes,2G146@200643|Bacteroidia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
WH2_k127_8851990_0	1392488.JHZY01000004_gene3278	3.555e-156	516.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1HYND@117743|Flavobacteriia,2XIPH@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
WH2_k127_8862987_0	420662.Mpe_A3793	1.274e-159	519.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,2VP2B@28216|Betaproteobacteria,1KJK7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Peptidase C39 family	cvaB	-	-	ko:K13409	ko02010,ko04626,map02010,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.110	-	-	ABC_membrane,ABC_tran,Peptidase_C39
WH2_k127_8881540_1	595460.RRSWK_01733	4.839e-123	401.0	COG0451@1|root,COG0451@2|Bacteria,2IWW0@203682|Planctomycetes	203682|Planctomycetes	GM	NAD- dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WH2_k127_8881540_0	760192.Halhy_2892	5.353e-175	564.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1IR5W@117747|Sphingobacteriia	976|Bacteroidetes	E	asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
WH2_k127_8882746_4	1267005.KB911263_gene1323	4.08e-18	94.0	COG0223@1|root,COG0223@2|Bacteria,1RAVE@1224|Proteobacteria,2UN4N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Formyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_N
WH2_k127_8882746_2	1166018.FAES_4094	7.747e-31	139.0	COG2319@1|root,COG2319@2|Bacteria,4NH20@976|Bacteroidetes,47JUN@768503|Cytophagia	976|Bacteroidetes	S	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
WH2_k127_8882746_1	269798.CHU_3004	1.921e-67	246.0	COG1807@1|root,COG1807@2|Bacteria,4P3UD@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8882746_0	1279009.ADICEAN_00951	1.244e-199	642.0	COG0471@1|root,COG0471@2|Bacteria,4NF52@976|Bacteroidetes,47NEH@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0471 Di- and tricarboxylate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
WH2_k127_8882746_3	388413.ALPR1_20843	8.328e-24	106.0	2CEJ5@1|root,2Z7RK@2|Bacteria,4NGWQ@976|Bacteroidetes,47N0C@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
WH2_k127_8887281_2	929556.Solca_1154	1.951e-36	140.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,4NDZ9@976|Bacteroidetes,1IQU6@117747|Sphingobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
WH2_k127_8887281_1	1408433.JHXV01000026_gene3024	1.408e-80	287.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,1HWT5@117743|Flavobacteriia,2PATT@246874|Cryomorphaceae	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
WH2_k127_8887281_0	1185876.BN8_03946	4.873e-132	438.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,47KTI@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised conserved protein UCP016719	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
WH2_k127_8887281_3	1198232.CYCME_2010	1.645e-15	78.0	COG3410@1|root,COG3410@2|Bacteria,1PRQ3@1224|Proteobacteria,1RR13@1236|Gammaproteobacteria,46271@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterized conserved protein (DUF2075)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2075
WH2_k127_8908608_2	468059.AUHA01000002_gene14	2.261e-14	74.0	COG0503@1|root,COG0503@2|Bacteria,4NP7K@976|Bacteroidetes,1IS3F@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
WH2_k127_8908608_1	468059.AUHA01000002_gene15	1.209e-40	162.0	COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,1ISN7@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA uptake protein and related DNA-binding	comEA	-	-	-	-	-	-	-	-	-	-	-	HHH_3
WH2_k127_8908608_0	1313301.AUGC01000010_gene925	9.224e-101	339.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
WH2_k127_8908608_3	1121097.JCM15093_2168	0.0008962	48.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,2FPA4@200643|Bacteroidia,4AKI6@815|Bacteroidaceae	976|Bacteroidetes	M	COG COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8913633_1	1123377.AUIV01000011_gene2103	1.399e-42	168.0	2F4SE@1|root,33XF5@2|Bacteria,1NWH2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8913633_0	1123277.KB893224_gene5885	9.14e-56	203.0	COG2110@1|root,COG2110@2|Bacteria,4NJJG@976|Bacteroidetes,47RH6@768503|Cytophagia	976|Bacteroidetes	S	phosphatase, C-terminal domain of histone macro H2A1 like protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
WH2_k127_8913633_2	1440053.JOEI01000038_gene205	6.811e-09	60.0	COG2110@1|root,COG2110@2|Bacteria,2I9GV@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Appr-1-p processing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
WH2_k127_8941456_4	398720.MED217_11469	1.227e-29	125.0	29CCT@1|root,2ZZB9@2|Bacteria,4NM9K@976|Bacteroidetes,1I189@117743|Flavobacteriia,2XJAC@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
WH2_k127_8941456_2	1121889.AUDM01000003_gene2303	1.028e-65	245.0	COG4188@1|root,COG4188@2|Bacteria,4P2MC@976|Bacteroidetes,1I8M4@117743|Flavobacteriia	976|Bacteroidetes	S	Chlorophyllase	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase
WH2_k127_8941456_3	1123400.KB904752_gene844	7.121e-38	161.0	COG2834@1|root,COG2931@1|root,COG3210@1|root,COG2834@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,1S1HJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cadherin_3,DUF4214,DUF4347,He_PIG,HemolysinCabind,PATR,VCBS
WH2_k127_8941456_0	1124780.ANNU01000065_gene456	1.436e-184	609.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,47KFG@768503|Cytophagia	976|Bacteroidetes	J	Poly A polymerase head domain	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
WH2_k127_8941456_1	760192.Halhy_5491	8.06e-88	305.0	COG2010@1|root,COG2010@2|Bacteria,4NHY4@976|Bacteroidetes,1IRVC@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8954877_0	1122135.KB893135_gene756	1.818e-130	425.0	COG3033@1|root,COG3033@2|Bacteria,1NG5U@1224|Proteobacteria,2TTAU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	catalyzes the formation of indole and pyruvate from tryptophan	-	-	4.1.99.2	ko:K01668	ko00350,map00350	-	R00728	RC00355,RC00364	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WH2_k127_8954877_1	761193.Runsl_2929	4.714e-102	341.0	COG2070@1|root,COG2070@2|Bacteria,4NEGW@976|Bacteroidetes,47JXU@768503|Cytophagia	976|Bacteroidetes	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8960272_0	1166018.FAES_0900	1.146e-31	127.0	COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,47R38@768503|Cytophagia	976|Bacteroidetes	J	PFAM translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
WH2_k127_8962534_1	1123037.AUDE01000021_gene2159	0.0002302	54.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,P_proprotein,Reprolysin_4,TSP_3
WH2_k127_8962534_0	1223410.KN050846_gene534	3.264e-21	109.0	COG1404@1|root,COG1404@2|Bacteria,4NQIZ@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8979251_0	153721.MYP_3706	6.915e-81	283.0	2C5KB@1|root,2ZCDW@2|Bacteria,4NMNY@976|Bacteroidetes,47PDN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_8979251_2	870187.Thini_2707	1.291e-08	68.0	COG0790@1|root,COG4249@1|root,COG0790@2|Bacteria,COG4249@2|Bacteria,1MWPA@1224|Proteobacteria,1RRKA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	FOG TPR repeat SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Peptidase_C14,Sel1
WH2_k127_8979251_1	1089547.KB913013_gene967	1.861e-12	72.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47JBS@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
WH2_k127_898620_0	435590.BVU_0272	8.912e-70	250.0	COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,2FNT5@200643|Bacteroidia,4ANBM@815|Bacteroidaceae	976|Bacteroidetes	M	Belongs to the peptidase S8 family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WH2_k127_898620_2	761193.Runsl_4089	1.533e-11	73.0	298K1@1|root,2ZVQX@2|Bacteria,4NNNX@976|Bacteroidetes,47Q8A@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_898620_1	929703.KE386491_gene1888	5.853e-16	78.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,47KX3@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
WH2_k127_8988323_1	643867.Ftrac_0820	3.43e-07	53.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes,47KTT@768503|Cytophagia	976|Bacteroidetes	Q	fumarylacetoacetate (FAA) hydrolase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
WH2_k127_8988323_2	1210908.HSB1_28900	0.0006758	51.0	arCOG06405@1|root,arCOG06405@2157|Archaea,2XT62@28890|Euryarchaeota,23T26@183963|Halobacteria	183963|Halobacteria	F	HTTM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
WH2_k127_8988323_0	1313421.JHBV01000041_gene3596	1.182e-19	91.0	COG1434@1|root,COG1434@2|Bacteria,4NNUT@976|Bacteroidetes	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
WH2_k127_8995960_2	485918.Cpin_2328	2.893e-31	129.0	COG2259@1|root,COG2259@2|Bacteria,4NSBJ@976|Bacteroidetes	976|Bacteroidetes	S	DoxX family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
WH2_k127_8995960_1	700598.Niako_3260	1.133e-69	249.0	COG0628@1|root,COG0628@2|Bacteria,4NPIX@976|Bacteroidetes,1IVAD@117747|Sphingobacteriia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WH2_k127_8995960_0	926549.KI421517_gene3483	9.581e-75	254.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,47KDV@768503|Cytophagia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WH2_k127_9018761_1	883.DvMF_1877	3.648e-22	101.0	arCOG08935@1|root,338YH@2|Bacteria,1N8JH@1224|Proteobacteria,43DKA@68525|delta/epsilon subdivisions,2WSNG@28221|Deltaproteobacteria,2MDSR@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9018761_2	865937.Gilli_1998	1.123e-16	87.0	COG2350@1|root,COG2350@2|Bacteria,4NNMS@976|Bacteroidetes,1I22W@117743|Flavobacteriia,2P7JT@244698|Gillisia	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
WH2_k127_9018761_0	316067.Geob_2091	1.633e-47	175.0	COG2320@1|root,COG2320@2|Bacteria,1RH46@1224|Proteobacteria,42TFI@68525|delta/epsilon subdivisions,2WP4H@28221|Deltaproteobacteria,43VWM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
WH2_k127_904714_1	1313421.JHBV01000021_gene4768	4.299e-23	109.0	28I9R@1|root,2Z8CE@2|Bacteria,4NE54@976|Bacteroidetes,1J12Q@117747|Sphingobacteriia	976|Bacteroidetes	S	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
WH2_k127_904714_0	1250278.JQNQ01000001_gene397	3.237e-74	268.0	COG0248@1|root,COG0248@2|Bacteria,4NEI0@976|Bacteroidetes,1HX36@117743|Flavobacteriia	976|Bacteroidetes	FP	exopolyphosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
WH2_k127_904714_2	1122176.KB903588_gene4558	1.774e-13	79.0	COG1361@1|root,COG3209@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,COG4932@2|Bacteria,4PKBQ@976|Bacteroidetes	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
WH2_k127_906361_0	700598.Niako_3929	1.302e-08	67.0	COG3291@1|root,COG3291@2|Bacteria,4NJQN@976|Bacteroidetes,1IXWG@117747|Sphingobacteriia	976|Bacteroidetes	M	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,IgGFc_binding,PKD,SprB,fn3
WH2_k127_9070174_0	929556.Solca_0021	8.923e-180	576.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1IPYI@117747|Sphingobacteriia	976|Bacteroidetes	O	with chaperone activity ATP-binding subunit	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
WH2_k127_9070174_1	1286632.P278_07080	4.276e-131	420.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1HY4P@117743|Flavobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WH2_k127_9090433_2	755732.Fluta_0072	2.004e-38	150.0	COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,1IKD0@117743|Flavobacteriia,2PAFR@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
WH2_k127_9090433_0	313596.RB2501_07485	6.213e-78	294.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,4NFZQ@976|Bacteroidetes,1HWXQ@117743|Flavobacteriia	976|Bacteroidetes	L	COG3893 Inactivated superfamily I helicase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
WH2_k127_9090433_4	1267211.KI669560_gene2738	9.466e-10	68.0	COG1404@1|root,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,1IU7A@117747|Sphingobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PKD,P_proprotein,Peptidase_S8,fn3
WH2_k127_9090433_1	1122176.KB903531_gene3071	2.768e-72	261.0	COG0745@1|root,COG0745@2|Bacteria,4NGXP@976|Bacteroidetes,1INQ4@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WH2_k127_9090433_3	1151127.KB906329_gene2585	3.764e-35	140.0	COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,1S5WY@1236|Gammaproteobacteria,1YMAI@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	Q	esterase	menI	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0061522,GO:0071704,GO:1901576,GO:1901661,GO:1901663	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT
WH2_k127_9116079_0	929703.KE386491_gene3908	1.035e-123	406.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,47KQS@768503|Cytophagia	976|Bacteroidetes	M	membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
WH2_k127_9123377_0	1317122.ATO12_18105	3.151e-64	230.0	COG3153@1|root,COG3153@2|Bacteria,4PMM1@976|Bacteroidetes,1IKUZ@117743|Flavobacteriia,2YI7Y@290174|Aquimarina	976|Bacteroidetes	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
WH2_k127_9134073_3	269798.CHU_2552	4.929e-19	99.0	COG2885@1|root,COG5184@1|root,COG2885@2|Bacteria,COG5184@2|Bacteria,4PM26@976|Bacteroidetes,47Y04@768503|Cytophagia	976|Bacteroidetes	GM	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9134073_2	929556.Solca_3504	1.992e-55	212.0	COG0590@1|root,COG0590@2|Bacteria,4NNJ2@976|Bacteroidetes,1ISDN@117747|Sphingobacteriia	976|Bacteroidetes	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
WH2_k127_9134073_1	760192.Halhy_4524	1.461e-107	368.0	COG2010@1|root,COG2010@2|Bacteria,4NEEJ@976|Bacteroidetes,1IP2H@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,FlgD_ig
WH2_k127_9134073_0	929556.Solca_4406	4.533e-196	627.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1IQ3R@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WH2_k127_9147459_0	1237149.C900_03094	1.474e-262	825.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,47MEE@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M49	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M49
WH2_k127_9147459_2	1123035.ARLA01000023_gene1210	3.315e-24	109.0	COG1978@1|root,COG1978@2|Bacteria,4NZNX@976|Bacteroidetes,1I716@117743|Flavobacteriia	976|Bacteroidetes	S	Ribonuclease H-like	-	-	-	-	-	-	-	-	-	-	-	-	RNaseH_like
WH2_k127_9147459_1	693979.Bache_0083	2.704e-41	156.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,2FMHT@200643|Bacteroidia,4AK8U@815|Bacteroidaceae	976|Bacteroidetes	M	Peptidase, M23	mepM_1	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
WH2_k127_9153246_0	945713.IALB_2039	1.062e-13	84.0	COG1361@1|root,COG1520@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	CHU_C,Cohesin,DUF11,Peptidase_S8,SBBP,SLH,VCBS
WH2_k127_9153246_1	525373.HMPREF0766_10406	5.002e-11	63.0	COG0073@1|root,COG0073@2|Bacteria,4NQ9I@976|Bacteroidetes,1ISRQ@117747|Sphingobacteriia	976|Bacteroidetes	J	Export-related chaperone CsaA	csaA	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
WH2_k127_9174152_1	746697.Aeqsu_1962	8.774e-06	55.0	2E09A@1|root,32VWX@2|Bacteria,4NT9W@976|Bacteroidetes,1I9TI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9174152_0	1185876.BN8_03379	1.437e-28	121.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,47M16@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
WH2_k127_9178335_0	518766.Rmar_2561	6.024e-51	190.0	COG1523@1|root,COG3291@1|root,COG1523@2|Bacteria,COG3291@2|Bacteria,4PKU5@976|Bacteroidetes,1FJYC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9178335_2	946362.XP_004996892.1	0.00086	51.0	28N08@1|root,2QUJ0@2759|Eukaryota	2759|Eukaryota	-	-	MUC4	GO:0001894,GO:0002218,GO:0002220,GO:0002223,GO:0002253,GO:0002376,GO:0002429,GO:0002682,GO:0002684,GO:0002757,GO:0002758,GO:0002764,GO:0002768,GO:0003008,GO:0003674,GO:0005102,GO:0005176,GO:0005198,GO:0005201,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005796,GO:0005886,GO:0005887,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0007586,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010669,GO:0012505,GO:0016020,GO:0016021,GO:0016266,GO:0019538,GO:0022600,GO:0023052,GO:0030197,GO:0030277,GO:0031012,GO:0031224,GO:0031226,GO:0031347,GO:0031349,GO:0031974,GO:0032501,GO:0034645,GO:0036211,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045088,GO:0045089,GO:0048518,GO:0048583,GO:0048584,GO:0048871,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060249,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0071704,GO:0071944,GO:0080134,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	-	ko:K22017	-	-	-	-	ko00000,ko04131	-	-	-	NIDO,VWD
WH2_k127_9178335_1	1121373.KB903621_gene1961	0.000149	54.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	3.2.1.4,3.4.24.40	ko:K01179,ko:K01406,ko:K07004	ko00500,ko01100,ko01503,map00500,map01100,map01503	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002	-	GH5,GH9	-	Calx-beta,Exo_endo_phos,HemolysinCabind,LTD,Laminin_G_3
WH2_k127_9190765_1	385682.AFSL01000064_gene1700	1.526e-84	283.0	COG0501@1|root,COG0501@2|Bacteria,4NE0J@976|Bacteroidetes,2FQJ1@200643|Bacteroidia,3XJXP@558415|Marinilabiliaceae	976|Bacteroidetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
WH2_k127_9190765_3	1150469.RSPPHO_00750	6.046e-05	46.0	28HAG@1|root,2Z7MV@2|Bacteria,1PMGH@1224|Proteobacteria,2U27X@28211|Alphaproteobacteria,2JPS8@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9190765_2	1304865.JAGF01000001_gene530	2.345e-12	70.0	2CA4F@1|root,33DCB@2|Bacteria,2GRQ2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9190765_0	1382306.JNIM01000001_gene667	5.94e-108	357.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WH2_k127_9194024_0	755732.Fluta_3508	1.409e-257	805.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,1HWP2@117743|Flavobacteriia,2PAB9@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
WH2_k127_9194024_1	1349822.NSB1T_08675	6.692e-16	86.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,2FN3A@200643|Bacteroidia,22WA9@171551|Porphyromonadaceae	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
WH2_k127_9198170_1	926562.Oweho_2803	9.591e-61	222.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1HWNN@117743|Flavobacteriia,2PAD0@246874|Cryomorphaceae	976|Bacteroidetes	E	Arginase family	fjo29	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
WH2_k127_9198170_0	504472.Slin_2030	1.095e-175	567.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,4NF9S@976|Bacteroidetes,47K7C@768503|Cytophagia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
WH2_k127_9203079_7	36874.HQ34_03435	6.935e-05	45.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,2FMVX@200643|Bacteroidia,22W7W@171551|Porphyromonadaceae	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
WH2_k127_9203079_1	755732.Fluta_4067	1.553e-210	662.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1HWVH@117743|Flavobacteriia,2PBCM@246874|Cryomorphaceae	976|Bacteroidetes	G	PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WH2_k127_9203079_0	1121481.AUAS01000006_gene877	2.953e-232	773.0	COG1520@1|root,COG2931@1|root,COG5184@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
WH2_k127_9203079_2	641526.ADIWIN_3516	9.567e-68	242.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,1HZYF@117743|Flavobacteriia	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
WH2_k127_9203079_3	714943.Mucpa_3142	5.498e-66	230.0	COG0494@1|root,COG0494@2|Bacteria,4NMHV@976|Bacteroidetes,1IRW6@117747|Sphingobacteriia	976|Bacteroidetes	L	NUDIX domain	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WH2_k127_9203079_5	1453500.AT05_06645	9.852e-25	112.0	COG1193@1|root,COG1193@2|Bacteria,4NNNV@976|Bacteroidetes,1I1ZP@117743|Flavobacteriia	976|Bacteroidetes	L	DNA mismatch repair protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2027,Smr
WH2_k127_9203079_4	1408433.JHXV01000005_gene2427	9.712e-32	135.0	2BUW8@1|root,32Q8B@2|Bacteria,4PBQS@976|Bacteroidetes,1ICQT@117743|Flavobacteriia,2PBTB@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9214465_1	1183438.GKIL_1638	5.272e-22	102.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	3.4.19.5	ko:K03088,ko:K13051	-	-	-	-	ko00000,ko01000,ko01002,ko03021	-	-	-	DUF4440,SnoaL_3
WH2_k127_9214465_0	504472.Slin_5745	1.207e-44	169.0	COG0705@1|root,COG0705@2|Bacteria,4NECA@976|Bacteroidetes,47N8U@768503|Cytophagia	976|Bacteroidetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WH2_k127_9214465_2	1280944.HY17_02890	1.529e-18	89.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2TRW1@28211|Alphaproteobacteria,43XF3@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_like,NTP_transferase
WH2_k127_9219827_0	1237149.C900_03022	2.04e-47	183.0	COG1708@1|root,COG1708@2|Bacteria,4NPRU@976|Bacteroidetes	976|Bacteroidetes	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
WH2_k127_9219827_1	391587.KAOT1_19402	2.352e-26	124.0	28X89@1|root,2ZJ6D@2|Bacteria,4NM59@976|Bacteroidetes,1I885@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WH2_k127_9219827_2	388413.ALPR1_16304	8.988e-24	106.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,47JNI@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
WH2_k127_9231441_0	1392490.JHZX01000001_gene869	5.428e-123	419.0	COG1361@1|root,COG4886@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,4NG93@976|Bacteroidetes,1HXFW@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
WH2_k127_923827_5	330214.NIDE0767	0.0002281	47.0	COG0206@1|root,COG0206@2|Bacteria,3J0D4@40117|Nitrospirae	40117|Nitrospirae	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
WH2_k127_923827_4	1168034.FH5T_20310	2.485e-12	68.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,2FQSQ@200643|Bacteroidia	976|Bacteroidetes	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
WH2_k127_923827_0	1151061.CAJY01000017_gene250	3.519e-183	582.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA2	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WH2_k127_923827_1	385682.AFSL01000064_gene1720	5.984e-71	249.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,2FNG0@200643|Bacteroidia,3XIUJ@558415|Marinilabiliaceae	976|Bacteroidetes	U	MotA/TolQ/ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
WH2_k127_923827_2	865937.Gilli_1642	1.432e-21	98.0	COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,1I25E@117743|Flavobacteriia,2P6SH@244698|Gillisia	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
WH2_k127_923827_3	985255.APHJ01000042_gene421	3.622e-17	87.0	COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,1I25E@117743|Flavobacteriia,2P6SH@244698|Gillisia	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
WH2_k127_9239244_0	1121373.KB903620_gene1987	1.69e-11	76.0	2FFMB@1|root,347IR@2|Bacteria,4P5CJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9266170_1	1122931.AUAE01000011_gene1819	1.084e-26	110.0	COG3169@1|root,COG3169@2|Bacteria,4NQH4@976|Bacteroidetes,2FT44@200643|Bacteroidia,22Y4C@171551|Porphyromonadaceae	976|Bacteroidetes	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
WH2_k127_9266170_0	1279009.ADICEAN_00402	2.26e-202	649.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,4NGF6@976|Bacteroidetes,47NEG@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
WH2_k127_9266170_2	987059.RBXJA2T_17434	1.691e-18	91.0	COG0745@1|root,COG0745@2|Bacteria,1N8Z8@1224|Proteobacteria,2VW99@28216|Betaproteobacteria,1KNT2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WH2_k127_9266170_3	65093.PCC7418_2862	1.258e-16	84.0	COG0784@1|root,COG0784@2|Bacteria,1G85J@1117|Cyanobacteria	1117|Cyanobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WH2_k127_9293505_0	1250278.JQNQ01000001_gene1259	8.709e-175	562.0	COG2931@1|root,COG2931@2|Bacteria,4PKJU@976|Bacteroidetes,1IJB7@117743|Flavobacteriia	976|Bacteroidetes	Q	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
WH2_k127_9293505_2	1227739.Hsw_4226	7.529e-25	113.0	COG0319@1|root,COG0319@2|Bacteria,4NS93@976|Bacteroidetes,47Q9Q@768503|Cytophagia	976|Bacteroidetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	-	-	-	-	-	-	-	-	-	UPF0054
WH2_k127_9293505_1	1279009.ADICEAN_01763	7.367e-36	141.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,47QUX@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
WH2_k127_9313931_3	1121373.KB903663_gene1056	4.046e-05	47.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,4NGF6@976|Bacteroidetes,47NEG@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefC	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
WH2_k127_9313931_0	1227739.Hsw_1973	1.688e-158	519.0	COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes,47M7Z@768503|Cytophagia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
WH2_k127_9313931_1	153721.MYP_2423	1.213e-80	276.0	COG3647@1|root,COG3647@2|Bacteria,4NMNV@976|Bacteroidetes,47RI0@768503|Cytophagia	976|Bacteroidetes	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
WH2_k127_9313931_2	1408433.JHXV01000002_gene324	1.604e-07	54.0	COG2050@1|root,COG2050@2|Bacteria,4P2ZC@976|Bacteroidetes,1ICQ7@117743|Flavobacteriia,2PBP8@246874|Cryomorphaceae	976|Bacteroidetes	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
WH2_k127_9322242_1	926562.Oweho_2340	1.392e-133	435.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1HXQH@117743|Flavobacteriia,2PAM6@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WH2_k127_9322242_3	755732.Fluta_1540	6.024e-28	129.0	COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,1I2V4@117743|Flavobacteriia,2PB44@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
WH2_k127_9322242_0	1168034.FH5T_08385	7.806e-148	497.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,2FQ6Y@200643|Bacteroidia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
WH2_k127_9322242_2	1550091.JROE01000004_gene1836	4.215e-30	129.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,1IS4Q@117747|Sphingobacteriia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
WH2_k127_9322242_4	1336803.PHEL49_1773	9.753e-19	95.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1HZ57@117743|Flavobacteriia,3VVDJ@52959|Polaribacter	976|Bacteroidetes	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
WH2_k127_9323865_3	111780.Sta7437_1338	1.336e-37	147.0	COG0589@1|root,COG0589@2|Bacteria,1G75A@1117|Cyanobacteria,3VKQZ@52604|Pleurocapsales	1117|Cyanobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WH2_k127_9323865_0	1366050.N234_04165	1.483e-133	437.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2VIRC@28216|Betaproteobacteria,1K4ET@119060|Burkholderiaceae	28216|Betaproteobacteria	G	sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,SGL
WH2_k127_9323865_1	1124780.ANNU01000056_gene3471	1.525e-62	222.0	COG1309@1|root,COG1309@2|Bacteria,4NEUA@976|Bacteroidetes,47P97@768503|Cytophagia	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WH2_k127_9323865_2	1250232.JQNJ01000001_gene2985	4.217e-55	199.0	COG2274@1|root,COG2274@2|Bacteria,4NFJF@976|Bacteroidetes,1HWYH@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
WH2_k127_9326109_1	926562.Oweho_2853	9.928e-78	267.0	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,1HYFZ@117743|Flavobacteriia,2PASJ@246874|Cryomorphaceae	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
WH2_k127_9326109_0	755732.Fluta_2226	5.662e-124	412.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,1HWQ7@117743|Flavobacteriia,2PAEN@246874|Cryomorphaceae	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
WH2_k127_934183_1	485918.Cpin_0364	3.111e-36	143.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IQN0@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
WH2_k127_934183_0	755732.Fluta_0362	0.0	1294.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,2PAGA@246874|Cryomorphaceae	976|Bacteroidetes	V	TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family	bepE_4	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
WH2_k127_934183_2	1341181.FLJC2902T_07910	2.044e-24	109.0	COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,1HYGI@117743|Flavobacteriia,2NT3F@237|Flavobacterium	976|Bacteroidetes	MU	outer membrane efflux protein	tolC	-	-	-	-	-	-	-	-	-	-	-	OEP
WH2_k127_9344329_1	1121472.AQWN01000007_gene1137	3.429e-73	263.0	COG1840@1|root,COG1840@2|Bacteria,1TSKP@1239|Firmicutes,24C6N@186801|Clostridia,263TA@186807|Peptococcaceae	186801|Clostridia	P	Bacterial extracellular solute-binding protein	futA1	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
WH2_k127_9344329_0	1227739.Hsw_1673	8.52e-80	276.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,47KKI@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WH2_k127_9370343_4	926549.KI421517_gene1951	5.077e-42	175.0	COG1905@1|root,COG1905@2|Bacteria,4NHIQ@976|Bacteroidetes,47JBB@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM NADH-quinone oxidoreductase, E subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
WH2_k127_9370343_0	760192.Halhy_0319	6.022e-198	631.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1IR4T@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
WH2_k127_9370343_5	883096.HMPREF9699_00957	1.507e-37	155.0	COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,1I1PJ@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
WH2_k127_9370343_2	760192.Halhy_0317	4.812e-87	291.0	COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,1INQ8@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
WH2_k127_9370343_3	1034807.FBFL15_0632	7.399e-46	169.0	COG0838@1|root,COG0838@2|Bacteria,4NQJB@976|Bacteroidetes,1I4DW@117743|Flavobacteriia,2NW8H@237|Flavobacterium	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
WH2_k127_9370343_1	1237149.C900_03459	3.294e-129	419.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,47JUB@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
WH2_k127_9370786_1	1121101.HMPREF1532_00415	2.748e-25	109.0	COG1169@1|root,COG1169@2|Bacteria,4NF6U@976|Bacteroidetes,2FNBU@200643|Bacteroidia,4AMWR@815|Bacteroidaceae	976|Bacteroidetes	HQ	Isochorismate synthase	entC	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
WH2_k127_9370786_0	869213.JCM21142_41609	2.426e-136	455.0	COG1165@1|root,COG1165@2|Bacteria,4NETZ@976|Bacteroidetes,47JS5@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
WH2_k127_9406269_0	880073.Calab_2100	2.853e-137	467.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
WH2_k127_9406269_3	861299.J421_0743	2.746e-50	196.0	COG4623@1|root,COG4623@2|Bacteria	2|Bacteria	M	carbon-oxygen lyase activity, acting on polysaccharides	mltF	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
WH2_k127_9406269_4	1406840.Q763_12555	6.712e-41	159.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1I1CI@117743|Flavobacteriia,2NTMP@237|Flavobacterium	976|Bacteroidetes	S	ACP phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
WH2_k127_9406269_2	1279009.ADICEAN_02252	1.928e-62	238.0	COG2972@1|root,COG2972@2|Bacteria,4NI09@976|Bacteroidetes,47K66@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
WH2_k127_9406269_1	761193.Runsl_3783	1.644e-90	305.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,47N62@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
WH2_k127_9406269_6	929703.KE386491_gene1575	2.182e-14	76.0	COG1028@1|root,COG1028@2|Bacteria,4NFXD@976|Bacteroidetes,47K99@768503|Cytophagia	976|Bacteroidetes	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH2_k127_9420573_0	886377.Murru_1117	2.418e-221	702.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1HWQN@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
WH2_k127_944087_0	761193.Runsl_3570	1.126e-49	180.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes,47MSW@768503|Cytophagia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
WH2_k127_944087_1	313606.M23134_00633	1.268e-35	149.0	28MS7@1|root,2ZB0M@2|Bacteria,4NHCQ@976|Bacteroidetes,47JQ9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9444749_2	443144.GM21_2642	2.467e-12	70.0	COG0746@1|root,COG0746@2|Bacteria,1RKCH@1224|Proteobacteria,42T8X@68525|delta/epsilon subdivisions,2WP3Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
WH2_k127_9444749_3	1123234.AUKI01000019_gene543	2.853e-07	55.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
WH2_k127_9444749_1	1121895.Q765_16045	4.099e-50	183.0	COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,1I24D@117743|Flavobacteriia,2NV6E@237|Flavobacterium	976|Bacteroidetes	H	Molybdopterin converting factor	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
WH2_k127_9444749_0	1313421.JHBV01000014_gene3843	5.578e-108	360.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,4NHA0@976|Bacteroidetes,1INZV@117747|Sphingobacteriia	976|Bacteroidetes	H	Molybdenum cofactor biosynthesis protein	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
WH2_k127_9445724_1	926562.Oweho_0814	1.509e-87	291.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,1HYKT@117743|Flavobacteriia,2PA8G@246874|Cryomorphaceae	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
WH2_k127_9445724_0	485917.Phep_3551	2.298e-239	761.0	COG0475@1|root,COG0490@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,4NGF6@976|Bacteroidetes,1IQ4D@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sodium hydrogen exchanger	nhaA	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C
WH2_k127_9445724_2	1300143.CCAV010000006_gene4205	1.254e-38	154.0	COG1073@1|root,COG1073@2|Bacteria,4NP3H@976|Bacteroidetes,1I92T@117743|Flavobacteriia,3ZPGU@59732|Chryseobacterium	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
WH2_k127_9447454_1	1124780.ANNU01000033_gene1335	2.6e-13	83.0	COG0457@1|root,COG0457@2|Bacteria,4NJ7X@976|Bacteroidetes,47NJZ@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
WH2_k127_9447454_0	1121904.ARBP01000001_gene5562	1.698e-30	134.0	28N54@1|root,2ZBAD@2|Bacteria,4NN5P@976|Bacteroidetes,47PNE@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9478686_0	1123057.P872_00220	1.885e-37	164.0	COG1345@1|root,COG1361@1|root,COG3210@1|root,COG3291@1|root,COG4935@1|root,COG5184@1|root,COG5492@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,4NM7C@976|Bacteroidetes,47RKX@768503|Cytophagia	976|Bacteroidetes	N	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHU_C
WH2_k127_9478686_1	313596.RB2501_12904	1.051e-13	86.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K08738,ko:K20276	ko00920,ko01100,ko01120,ko01524,ko02020,ko02024,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map02024,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Beta_helix,CBM_6,CHU_C,CW_binding_2,DUF11,GSDH,MAM,Malectin,PKD,fn3
WH2_k127_9478686_2	153721.MYP_4087	0.0003907	54.0	COG2755@1|root,COG3866@1|root,COG2755@2|Bacteria,COG3866@2|Bacteria,4P09P@976|Bacteroidetes,47XYK@768503|Cytophagia	976|Bacteroidetes	EG	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_3,Laminin_G_3,Lipase_GDSL_2,fn3
WH2_k127_9492828_0	926549.KI421517_gene3524	1.379e-90	313.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,47M7W@768503|Cytophagia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9492828_2	309807.SRU_0663	1.359e-25	114.0	COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,1FJIV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
WH2_k127_9492828_1	762903.Pedsa_3676	6.441e-31	129.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,1ISDB@117747|Sphingobacteriia	976|Bacteroidetes	F	Pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
WH2_k127_9492828_3	981369.JQMJ01000004_gene6110	5.834e-05	50.0	COG0726@1|root,COG2247@1|root,COG0726@2|Bacteria,COG2247@2|Bacteria,2IATQ@201174|Actinobacteria,2NFX0@228398|Streptacidiphilus	201174|Actinobacteria	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9504297_0	755732.Fluta_2885	5.642e-150	509.0	COG3291@1|root,COG3291@2|Bacteria,4PI0H@976|Bacteroidetes,1IGQE@117743|Flavobacteriia,2PBJ6@246874|Cryomorphaceae	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
WH2_k127_9507772_2	404589.Anae109_4199	2.154e-17	92.0	COG1807@1|root,COG1807@2|Bacteria,1RJ9T@1224|Proteobacteria	1224|Proteobacteria	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
WH2_k127_9507772_1	1237149.C900_03625	5.472e-20	105.0	COG3227@1|root,COG3291@1|root,COG4733@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4NGRJ@976|Bacteroidetes,47JD6@768503|Cytophagia	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43,fn3
WH2_k127_9507772_0	760192.Halhy_6848	1.251e-36	158.0	COG4932@1|root,COG4932@2|Bacteria,4NKIK@976|Bacteroidetes	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9516726_0	755732.Fluta_2092	2.479e-66	250.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1I0R3@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
WH2_k127_9516726_1	1408473.JHXO01000003_gene2540	1.123e-14	78.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
WH2_k127_9520153_0	1237149.C900_03625	1.42e-15	91.0	COG3227@1|root,COG3291@1|root,COG4733@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4NGRJ@976|Bacteroidetes,47JD6@768503|Cytophagia	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43,fn3
WH2_k127_9520153_1	768671.ThimaDRAFT_4510	7.501e-05	53.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVK@1236|Gammaproteobacteria,1X2B5@135613|Chromatiales	135613|Chromatiales	NU	PFAM Sulphatase-modifying factor	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA
WH2_k127_952665_3	755732.Fluta_0875	1.396e-54	198.0	COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,1HWKF@117743|Flavobacteriia,2PAXI@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Scaffold protein Nfu NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
WH2_k127_952665_1	886377.Murru_0989	8.855e-99	336.0	COG0318@1|root,COG0318@2|Bacteria,4NDXK@976|Bacteroidetes,1IJB2@117743|Flavobacteriia	976|Bacteroidetes	IQ	acyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
WH2_k127_952665_5	1408433.JHXV01000007_gene2952	5.899e-17	89.0	2A5B1@1|root,30U0G@2|Bacteria,4PHGE@976|Bacteroidetes,1IC33@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_952665_0	1237149.C900_04445	9.974e-158	515.0	COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes,47N3M@768503|Cytophagia	976|Bacteroidetes	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
WH2_k127_952665_2	755732.Fluta_2306	3.225e-85	296.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,1HXVZ@117743|Flavobacteriia,2PA7P@246874|Cryomorphaceae	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
WH2_k127_952665_4	1313421.JHBV01000039_gene2694	2.632e-39	152.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
WH2_k127_9530326_2	443143.GM18_1541	2.48e-22	113.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions,2WT5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_C,PKD,Pur_ac_phosph_N
WH2_k127_9530326_1	5786.XP_003286127.1	2.986e-28	133.0	KOG1225@1|root,KOG1225@2759|Eukaryota	2759|Eukaryota	L	regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9530326_0	1122176.KB903598_gene4712	1.356e-48	198.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CW_binding_1,HYR
WH2_k127_9541083_0	1089547.KB913013_gene4776	1.056e-126	422.0	COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,47J8Y@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
WH2_k127_9541083_1	313594.PI23P_05357	5.937e-49	176.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,3VX0F@52959|Polaribacter	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
WH2_k127_9544822_0	1408433.JHXV01000009_gene1331	0.0	1020.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1HY3C@117743|Flavobacteriia,2PA69@246874|Cryomorphaceae	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
WH2_k127_9548992_7	1408433.JHXV01000028_gene2117	1.161e-05	55.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes,1IG37@117743|Flavobacteriia,2PB68@246874|Cryomorphaceae	976|Bacteroidetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
WH2_k127_9548992_9	6183.Smp_046750.1	3.142e-05	55.0	KOG0266@1|root,KOG0266@2759|Eukaryota,38D84@33154|Opisthokonta,3BCYJ@33208|Metazoa,3CUP4@33213|Bilateria	33208|Metazoa	S	WD repeat-containing protein 5	wdr-5.3	GO:0001085,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006325,GO:0006464,GO:0006479,GO:0006807,GO:0006996,GO:0007275,GO:0007568,GO:0008134,GO:0008150,GO:0008152,GO:0008213,GO:0008340,GO:0009987,GO:0010259,GO:0016043,GO:0016569,GO:0016570,GO:0016571,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0030154,GO:0031974,GO:0031981,GO:0032259,GO:0032501,GO:0032502,GO:0032991,GO:0034708,GO:0034968,GO:0035097,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044666,GO:0048856,GO:0048869,GO:0051276,GO:0051568,GO:0060290,GO:0070013,GO:0071704,GO:0071840,GO:1901564,GO:1902494,GO:1990234	-	ko:K14963	ko04934,map04934	-	-	-	ko00000,ko00001,ko03036	-	-	-	WD40
WH2_k127_9548992_4	1453500.AT05_07335	5.9e-57	213.0	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,1HZ1Y@117743|Flavobacteriia	976|Bacteroidetes	I	thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WH2_k127_9548992_5	1123269.NX02_25940	3.8e-15	84.0	2ERBI@1|root,33IX6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9548992_2	1150600.ADIARSV_1902	1.288e-102	344.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,1INZA@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WH2_k127_9548992_3	755732.Fluta_1712	1.035e-85	292.0	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,1HXDX@117743|Flavobacteriia,2PAPA@246874|Cryomorphaceae	976|Bacteroidetes	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
WH2_k127_9548992_1	203275.BFO_0184	1.018e-117	393.0	COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,2FM3E@200643|Bacteroidia,22VV2@171551|Porphyromonadaceae	976|Bacteroidetes	EJ	L-asparaginase, type I	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
WH2_k127_9548992_0	1166018.FAES_1792	4.854e-149	478.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,47JGV@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
WH2_k127_9552668_2	929556.Solca_3976	2.847e-43	163.0	COG4870@1|root,COG4870@2|Bacteria,4NGK1@976|Bacteroidetes,1INPA@117747|Sphingobacteriia	976|Bacteroidetes	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,Peptidase_C1
WH2_k127_9552668_1	1122179.KB890416_gene2721	8.055e-53	214.0	COG1404@1|root,COG1404@2|Bacteria,4PM4C@976|Bacteroidetes,1J1A0@117747|Sphingobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,Reprolysin_4,fn3
WH2_k127_9552668_0	1121904.ARBP01000006_gene3681	1.07e-85	319.0	COG3419@1|root,COG4447@1|root,COG4932@1|root,COG5184@1|root,COG3419@2|Bacteria,COG4447@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,4NNEI@976|Bacteroidetes	976|Bacteroidetes	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF1566
WH2_k127_9557573_3	886379.AEWI01000052_gene2670	1.956e-26	122.0	COG0438@1|root,COG0438@2|Bacteria,4NZMT@976|Bacteroidetes,2G1JS@200643|Bacteroidia,3XKI2@558415|Marinilabiliaceae	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
WH2_k127_9557573_1	929562.Emtol_1083	3.464e-79	269.0	COG0491@1|root,COG0491@2|Bacteria,4NPPW@976|Bacteroidetes,47MDW@768503|Cytophagia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	ccrA	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
WH2_k127_9557573_5	1392489.JPOL01000002_gene2726	0.0003129	47.0	2DSC3@1|root,33FFZ@2|Bacteria,4NXX2@976|Bacteroidetes,1I6RY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9557573_0	313598.MED152_05000	7.331e-114	380.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,1HXDA@117743|Flavobacteriia,3VWNZ@52959|Polaribacter	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
WH2_k127_9557573_2	1158292.JPOE01000005_gene814	1.128e-52	195.0	COG1045@1|root,COG1045@2|Bacteria,1RIYD@1224|Proteobacteria,2VYGS@28216|Betaproteobacteria,1KP7C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
WH2_k127_9557573_4	1168289.AJKI01000012_gene310	3.976e-06	53.0	COG0463@1|root,COG0463@2|Bacteria,4NRHZ@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH2_k127_957819_0	1379270.AUXF01000004_gene3115	1.351e-45	166.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1ZSUZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
WH2_k127_957819_1	755732.Fluta_1615	2.113e-09	70.0	COG1404@1|root,COG1404@2|Bacteria,4NVH2@976|Bacteroidetes,1IKDH@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9589670_0	755732.Fluta_1600	4.406e-139	449.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,1HX0S@117743|Flavobacteriia,2PAI3@246874|Cryomorphaceae	976|Bacteroidetes	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
WH2_k127_9589670_1	714943.Mucpa_4651	7.207e-23	102.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IRNR@117747|Sphingobacteriia	976|Bacteroidetes	U	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,PKD,SASA
WH2_k127_9589670_2	1121013.P873_06955	1.093e-09	60.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,1X4BU@135614|Xanthomonadales	135614|Xanthomonadales	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
WH2_k127_959100_5	509635.N824_15230	5.027e-32	135.0	COG2010@1|root,COG2010@2|Bacteria,4NEEJ@976|Bacteroidetes,1IP2H@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,FlgD_ig
WH2_k127_959100_2	1380384.JADN01000003_gene855	1.096e-62	226.0	COG0697@1|root,COG0697@2|Bacteria,4NE8D@976|Bacteroidetes,1HXCW@117743|Flavobacteriia	976|Bacteroidetes	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WH2_k127_959100_3	1124780.ANNU01000064_gene442	3.148e-45	170.0	COG2928@1|root,COG2928@2|Bacteria,4NR4F@976|Bacteroidetes,47QB1@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
WH2_k127_959100_4	1120965.AUBV01000009_gene2974	2.485e-41	167.0	COG2315@1|root,COG2315@2|Bacteria,4NS6J@976|Bacteroidetes,47R6I@768503|Cytophagia	976|Bacteroidetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
WH2_k127_959100_1	1121895.Q765_12905	3.85e-72	253.0	COG1878@1|root,COG1878@2|Bacteria,4NFXM@976|Bacteroidetes,1HWQP@117743|Flavobacteriia,2NSD1@237|Flavobacterium	976|Bacteroidetes	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
WH2_k127_959100_0	1122605.KB893634_gene4241	2.485e-102	346.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,1IR75@117747|Sphingobacteriia	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
WH2_k127_959100_6	338969.Rfer_2434	0.000601	43.0	COG2249@1|root,COG2249@2|Bacteria,1RAP1@1224|Proteobacteria,2VRHH@28216|Betaproteobacteria,4AJ8V@80864|Comamonadaceae	28216|Betaproteobacteria	S	Flavodoxin-like fold	-	-	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_2
WH2_k127_9627945_5	1120983.KB894571_gene2219	1.407e-06	53.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2TSWX@28211|Alphaproteobacteria,1JNFH@119043|Rhodobiaceae	28211|Alphaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
WH2_k127_9627945_3	153721.MYP_4845	6.967e-34	134.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,47V8W@768503|Cytophagia	976|Bacteroidetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
WH2_k127_9627945_1	411154.GFO_1096	1.184e-56	205.0	COG0566@1|root,COG0566@2|Bacteria,4NFH3@976|Bacteroidetes,1HX2E@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
WH2_k127_9627945_0	1173025.GEI7407_3298	7.137e-61	219.0	COG0259@1|root,COG0259@2|Bacteria,1G0HC@1117|Cyanobacteria,1HA00@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.pdxH	PNP_phzG_C,Putative_PNPOx
WH2_k127_9627945_2	1408433.JHXV01000009_gene1299	5.965e-53	192.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,1HXJN@117743|Flavobacteriia,2PAZ7@246874|Cryomorphaceae	976|Bacteroidetes	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
WH2_k127_9627945_4	755732.Fluta_3488	1.38e-28	116.0	COG0115@1|root,COG0115@2|Bacteria,4NG0G@976|Bacteroidetes,1HYPS@117743|Flavobacteriia,2PAUN@246874|Cryomorphaceae	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WH2_k127_9637506_4	278957.ABEA03000015_gene3315	0.0006317	43.0	COG0513@1|root,COG0513@2|Bacteria,46U0S@74201|Verrucomicrobia,3K72X@414999|Opitutae	414999|Opitutae	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
WH2_k127_9637506_0	1121104.AQXH01000005_gene191	1.425e-127	421.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,1IP0F@117747|Sphingobacteriia	976|Bacteroidetes	S	HI0933 family	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
WH2_k127_9637506_2	1122179.KB890422_gene2265	1.192e-26	119.0	COG3449@1|root,COG3449@2|Bacteria,4NMS1@976|Bacteroidetes	976|Bacteroidetes	L	SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
WH2_k127_9637506_3	1120968.AUBX01000015_gene3509	9.055e-11	70.0	2ETUA@1|root,33MBM@2|Bacteria,4NYNV@976|Bacteroidetes	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
WH2_k127_9637506_1	700598.Niako_6291	6.225e-110	381.0	COG3087@1|root,COG3087@2|Bacteria,4PNV5@976|Bacteroidetes	976|Bacteroidetes	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9638984_0	700598.Niako_5744	2.56e-130	425.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,1IPKJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WH2_k127_9638984_1	927658.AJUM01000024_gene2599	1.284e-80	278.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,2FPJM@200643|Bacteroidia,3XJVW@558415|Marinilabiliaceae	976|Bacteroidetes	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
WH2_k127_9646185_4	1122179.KB890480_gene3183	4.77e-17	81.0	COG1393@1|root,COG1393@2|Bacteria,4NSAW@976|Bacteroidetes,1IT7Y@117747|Sphingobacteriia	976|Bacteroidetes	P	ArsC family	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
WH2_k127_9646185_0	755732.Fluta_1775	1.011e-173	558.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1HX2W@117743|Flavobacteriia,2PAMH@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Sigma-54 factor, Activator interacting domain (AID)	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
WH2_k127_9646185_3	869213.JCM21142_193	8.823e-20	97.0	COG0671@1|root,COG0671@2|Bacteria,4NUPJ@976|Bacteroidetes,47PT7@768503|Cytophagia	976|Bacteroidetes	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9646185_1	926549.KI421517_gene2439	2.156e-140	458.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,47K89@768503|Cytophagia	976|Bacteroidetes	G	TIGRFAM glucose galactose transporter	gluP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
WH2_k127_9646185_2	1279009.ADICEAN_01106	8.042e-120	396.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,47JM5@768503|Cytophagia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
WH2_k127_9653112_0	1313421.JHBV01000028_gene1857	2.509e-61	223.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
WH2_k127_9653112_1	755732.Fluta_3336	0.0005807	50.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2PBEH@246874|Cryomorphaceae	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
WH2_k127_9660077_2	714943.Mucpa_1441	8.246e-35	143.0	COG2911@1|root,COG3391@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,4NHHA@976|Bacteroidetes,1J194@117747|Sphingobacteriia	976|Bacteroidetes	MU	C-terminal domain of CHU protein family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_4,CHU_C,Calx-beta,He_PIG,NHL,TIG,fn3
WH2_k127_9660077_1	880073.Calab_1648	7.621e-40	152.0	COG4731@1|root,COG4731@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
WH2_k127_9660077_0	153721.MYP_2228	7.454e-250	803.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
WH2_k127_9672526_2	1237149.C900_04746	2.307e-101	336.0	2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,47MEQ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9672526_0	1408433.JHXV01000002_gene467	1.303e-186	596.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1HWS1@117743|Flavobacteriia,2PAKC@246874|Cryomorphaceae	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
WH2_k127_9672526_1	926562.Oweho_1753	8.824e-148	475.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,1HXWT@117743|Flavobacteriia,2PAAG@246874|Cryomorphaceae	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
WH2_k127_9672526_3	880070.Cycma_2374	8.408e-72	253.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,47JG4@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
WH2_k127_9686851_3	641143.HMPREF9331_02409	1.508e-09	65.0	COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,1HXNF@117743|Flavobacteriia,1ERGW@1016|Capnocytophaga	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
WH2_k127_9686851_1	1341155.FSS13T_06090	7.862e-43	171.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1I1F1@117743|Flavobacteriia,2NZZP@237|Flavobacterium	976|Bacteroidetes	G	Polysaccharide deacetylase	pgdA	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	DUF3298,Polysacc_deac_1
WH2_k127_9686851_4	1121918.ARWE01000001_gene3140	5.418e-06	57.0	COG2834@1|root,COG2834@2|Bacteria,1NDM6@1224|Proteobacteria,42VR3@68525|delta/epsilon subdivisions,2WRTR@28221|Deltaproteobacteria,43VBM@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein carrier protein LolA	-	-	-	-	-	-	-	-	-	-	-	-	LolA
WH2_k127_9686851_2	616991.JPOO01000001_gene3728	5.935e-11	70.0	COG0764@1|root,COG0764@2|Bacteria,4NSGQ@976|Bacteroidetes,1I431@117743|Flavobacteriia	976|Bacteroidetes	I	dehydratase	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
WH2_k127_9686851_0	1434325.AZQN01000002_gene728	4.971e-121	405.0	COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,4NETR@976|Bacteroidetes,47MJC@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DUF2062,Glycos_transf_2
WH2_k127_9705827_1	1406840.Q763_05245	1.603e-29	130.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,1HXRE@117743|Flavobacteriia,2NSQF@237|Flavobacterium	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WH2_k127_9705827_0	1280380.KR100_02380	1.871e-30	141.0	COG2931@1|root,COG3420@1|root,COG2931@2|Bacteria,COG3420@2|Bacteria,1G1I0@1117|Cyanobacteria,1GZV9@1129|Synechococcus	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
WH2_k127_9705827_2	673862.BABL1_1000	1.061e-16	96.0	COG1520@1|root,COG3391@1|root,COG1520@2|Bacteria,COG3391@2|Bacteria,1QWRQ@1224|Proteobacteria	1224|Proteobacteria	M	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Abhydrolase_3,Cadherin-like,Cadherin_3,TIG,VCBS
WH2_k127_9713863_2	457398.HMPREF0326_00609	1.93e-26	119.0	COG1216@1|root,COG1216@2|Bacteria,1RDAK@1224|Proteobacteria,42U4I@68525|delta/epsilon subdivisions,2WQB2@28221|Deltaproteobacteria,2MHB9@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH2_k127_9713863_1	385682.AFSL01000047_gene524	1.426e-54	208.0	COG0438@1|root,COG0438@2|Bacteria,4NPDT@976|Bacteroidetes,2FSPY@200643|Bacteroidia	976|Bacteroidetes	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
WH2_k127_9713863_0	861299.J421_1701	1.693e-62	219.0	COG1696@1|root,COG1696@2|Bacteria,1ZV39@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
WH2_k127_9718327_0	1121481.AUAS01000006_gene810	9.515e-112	368.0	COG0379@1|root,COG0379@2|Bacteria,4NDVX@976|Bacteroidetes,47MXK@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
WH2_k127_9718327_1	1189619.pgond44_13162	3.954e-77	261.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXGF@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
WH2_k127_9722659_0	755732.Fluta_2097	1.177e-56	217.0	28M1N@1|root,2ZAGE@2|Bacteria,4NIDD@976|Bacteroidetes,1I8D6@117743|Flavobacteriia,2PARN@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9741452_0	1121889.AUDM01000012_gene1451	1.14e-64	240.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF1080,PKD,fn3
WH2_k127_9741452_1	761193.Runsl_2593	4.076e-27	116.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,47JN6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WH2_k127_9753794_0	1123035.ARLA01000023_gene1188	4.266e-40	150.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1HY80@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WH2_k127_9753794_1	1123277.KB893243_gene268	6.788e-37	153.0	COG0810@1|root,COG0810@2|Bacteria,4NW2E@976|Bacteroidetes,47YB7@768503|Cytophagia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	Peptidase_M56,TonB_C
WH2_k127_9753794_2	743722.Sph21_1401	2.728e-15	78.0	COG3682@1|root,COG3682@2|Bacteria,4NNVM@976|Bacteroidetes,1IT90@117747|Sphingobacteriia	976|Bacteroidetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
WH2_k127_9772586_1	1408473.JHXO01000012_gene292	9.508e-88	294.0	COG2207@1|root,COG2207@2|Bacteria,4NMRA@976|Bacteroidetes,2G2TU@200643|Bacteroidia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
WH2_k127_9772586_2	1379270.AUXF01000002_gene1279	6.919e-32	128.0	COG2361@1|root,COG2361@2|Bacteria,1ZUWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
WH2_k127_9772586_3	498848.TaqDRAFT_3957	1.922e-18	89.0	COG1669@1|root,COG1669@2|Bacteria,1WKNV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	PFAM DNA polymerase beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
WH2_k127_9772586_4	1408473.JHXO01000012_gene292	0.0004861	48.0	COG2207@1|root,COG2207@2|Bacteria,4NMRA@976|Bacteroidetes,2G2TU@200643|Bacteroidia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
WH2_k127_9772586_0	926556.Echvi_3338	1.169e-214	677.0	COG0069@1|root,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,47MYG@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the glutamate synthase family	glt	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
WH2_k127_9774556_0	886379.AEWI01000018_gene1270	1.702e-185	601.0	COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,2FM0U@200643|Bacteroidia,3XIWA@558415|Marinilabiliaceae	976|Bacteroidetes	M	Penicillin-binding Protein dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
WH2_k127_9774556_2	1408433.JHXV01000032_gene1121	4.49e-10	68.0	2A9I2@1|root,30YQD@2|Bacteria,4PCM2@976|Bacteroidetes,1IMSU@117743|Flavobacteriia,2PC1C@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9774556_1	742725.HMPREF9450_01336	2.961e-68	237.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,2FMPT@200643|Bacteroidia,22U6D@171550|Rikenellaceae	976|Bacteroidetes	H	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
WH2_k127_9779086_2	504472.Slin_1359	1.632e-23	105.0	COG2346@1|root,COG2346@2|Bacteria,4NVGJ@976|Bacteroidetes,47XVB@768503|Cytophagia	976|Bacteroidetes	S	COG2346, Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
WH2_k127_9779086_0	992406.RIA_0277	2.936e-55	206.0	COG0569@1|root,COG0569@2|Bacteria,4NGRQ@976|Bacteroidetes,1HYTE@117743|Flavobacteriia	976|Bacteroidetes	P	COG0569 K transport systems NAD-binding component	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
WH2_k127_9779086_1	867902.Ornrh_0950	7.017e-25	106.0	COG0168@1|root,COG0168@2|Bacteria,4NF7R@976|Bacteroidetes,1HY9Z@117743|Flavobacteriia	976|Bacteroidetes	P	potassium uptake protein, TrkH family	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
WH2_k127_9798642_1	1122176.KB903532_gene2516	1.808e-63	228.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1INS2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S
WH2_k127_9798642_0	1120965.AUBV01000006_gene2152	2.608e-106	357.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,47N6X@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
WH2_k127_9798642_2	1123248.KB893315_gene3130	4.038e-29	126.0	COG1670@1|root,COG1670@2|Bacteria,4NV0H@976|Bacteroidetes,1IYVQ@117747|Sphingobacteriia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WH2_k127_9798642_3	1089547.KB913013_gene107	5.796e-18	86.0	COG1738@1|root,COG1738@2|Bacteria,4NFP3@976|Bacteroidetes,47J8X@768503|Cytophagia	976|Bacteroidetes	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
WH2_k127_9824792_0	1122179.KB890451_gene4532	1.011e-10	76.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,He_PIG,Laminin_G_3,VCBS
WH2_k127_9831094_0	926562.Oweho_2634	2.582e-265	837.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1HXZE@117743|Flavobacteriia,2PAAI@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
WH2_k127_9831094_1	1227739.Hsw_3718	7.83e-30	128.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
WH2_k127_9833034_4	479434.Sthe_2194	3.923e-26	114.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,T4_deiodinase
WH2_k127_9833034_0	760192.Halhy_4151	2.115e-136	454.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1IQJT@117747|Sphingobacteriia	976|Bacteroidetes	V	Mate efflux family protein	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
WH2_k127_9833034_2	1313421.JHBV01000029_gene2009	1.268e-53	203.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
WH2_k127_9833034_3	742767.HMPREF9456_03195	3.08e-27	116.0	2CZWI@1|root,32T79@2|Bacteria,4NSNW@976|Bacteroidetes,2FTY4@200643|Bacteroidia,22YDH@171551|Porphyromonadaceae	976|Bacteroidetes	S	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9833034_1	1121373.KB903625_gene3160	1.967e-88	322.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4PMED@976|Bacteroidetes,47Y31@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
WH2_k127_983502_1	1121957.ATVL01000014_gene1459	1.785e-18	97.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_983502_0	1408473.JHXO01000001_gene2185	5.361e-54	200.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,2FP14@200643|Bacteroidia	976|Bacteroidetes	S	ComF family	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
WH2_k127_985487_2	1356852.N008_07675	7.375e-16	89.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,47KTA@768503|Cytophagia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
WH2_k127_985487_1	1189612.A33Q_2412	3.684e-28	115.0	2C2TP@1|root,33BV9@2|Bacteria,4NXY4@976|Bacteroidetes,47T6I@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_985487_3	143224.JQMD01000002_gene1636	1.187e-05	56.0	COG0484@1|root,COG0484@2|Bacteria,4NE4X@976|Bacteroidetes,1HXJ8@117743|Flavobacteriia	976|Bacteroidetes	O	molecular chaperone	dnaJ2	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
WH2_k127_985487_0	1123057.P872_14365	2.649e-50	203.0	COG3386@1|root,COG4733@1|root,COG3386@2|Bacteria,COG4733@2|Bacteria,4NIJT@976|Bacteroidetes,47XYW@768503|Cytophagia	976|Bacteroidetes	G	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5008,DUF5122
WH2_k127_986611_1	755732.Fluta_0866	9.46e-33	132.0	COG2913@1|root,COG2913@2|Bacteria,4NP4N@976|Bacteroidetes,1I2RK@117743|Flavobacteriia	976|Bacteroidetes	J	Domain of unknown function (DUF4476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4476,SmpA_OmlA
WH2_k127_986611_2	880073.Calab_3761	1.302e-08	67.0	COG1462@1|root,COG1462@2|Bacteria,2NQ4P@2323|unclassified Bacteria	2|Bacteria	M	Curli production assembly transport component CsgG	csgG	-	-	-	-	-	-	-	-	-	-	-	CsgG,DUF4384,FlgT_C,PG_binding_1
WH2_k127_986611_0	1313301.AUGC01000001_gene1794	3.54e-62	231.0	2DMDZ@1|root,32QUA@2|Bacteria,4NSIY@976|Bacteroidetes	976|Bacteroidetes	S	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
WH2_k127_9876229_0	865938.Weevi_1967	4.973e-88	301.0	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,1HYDH@117743|Flavobacteriia	976|Bacteroidetes	F	phosphorylase	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
WH2_k127_9876229_1	755732.Fluta_2695	3.735e-53	192.0	2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,1HY5Y@117743|Flavobacteriia,2PBHM@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
WH2_k127_9878637_0	1048983.EL17_01685	3.734e-59	223.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NGZV@976|Bacteroidetes,47TBR@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,IgGFc_binding,PKD,SprB
WH2_k127_9878637_1	620914.JH621274_gene375	8.283e-13	71.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1HWU2@117743|Flavobacteriia,2YHUV@290174|Aquimarina	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
WH2_k127_9889826_1	761193.Runsl_5598	5.96e-06	58.0	COG1361@1|root,COG1409@1|root,COG1361@2|Bacteria,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,LTD,Phytase-like,Reprolysin_5,SLH
WH2_k127_9889826_0	1313421.JHBV01000014_gene3816	4.196e-40	164.0	COG3291@1|root,COG5306@1|root,COG3291@2|Bacteria,COG5306@2|Bacteria,4NRAB@976|Bacteroidetes	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Calycin_like,PCMD
WH2_k127_9889826_2	1370122.JHXQ01000001_gene412	0.0004976	51.0	COG3794@1|root,COG3794@2|Bacteria,1MZWU@1224|Proteobacteria,2UC7P@28211|Alphaproteobacteria,4BJJ4@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Copper-bind
WH2_k127_9906589_0	1111069.TCCBUS3UF1_17270	8.985e-18	92.0	COG1572@1|root,COG1572@2|Bacteria,1WM7M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
WH2_k127_9906589_1	1121898.Q766_11140	1.007e-06	54.0	COG3187@1|root,COG4935@1|root,COG5184@1|root,COG3187@2|Bacteria,COG4935@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K03668,ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	Cadherin-like,META,P_proprotein
WH2_k127_9922652_1	999419.HMPREF1077_00389	2.188e-48	177.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,2FMPI@200643|Bacteroidia,22W6D@171551|Porphyromonadaceae	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
WH2_k127_9922652_0	643867.Ftrac_2170	1.55e-50	194.0	COG3291@1|root,COG3291@2|Bacteria,4NGJJ@976|Bacteroidetes,47KNC@768503|Cytophagia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9922935_0	929556.Solca_2902	1.19e-53	193.0	COG1510@1|root,COG1510@2|Bacteria,4NQPD@976|Bacteroidetes,1ISGU@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,MarR_2,TrmB
WH2_k127_9922935_1	1157708.KB907456_gene2218	5.731e-37	150.0	COG0500@1|root,COG2226@2|Bacteria,1Q8SR@1224|Proteobacteria,2VZQ6@28216|Betaproteobacteria,4AGJP@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WH2_k127_9941806_1	1408433.JHXV01000007_gene2924	2.236e-58	213.0	COG3325@1|root,COG3325@2|Bacteria	2|Bacteria	G	chitin binding	-	-	3.2.1.14,3.2.1.40	ko:K01183,ko:K05989	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,CBM_6,Glyco_hydro_18,Glyco_hydro_43,UnbV_ASPIC,VCBS
WH2_k127_9941806_0	760192.Halhy_6848	9.398e-64	230.0	COG4932@1|root,COG4932@2|Bacteria,4NKIK@976|Bacteroidetes	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9952449_0	1185876.BN8_00877	8.577e-59	216.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47KZI@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH2_k127_9952449_2	1484460.JSWG01000015_gene1167	2.271e-37	155.0	COG1053@1|root,COG1053@2|Bacteria,4NNNU@976|Bacteroidetes,1I2QW@117743|Flavobacteriia	976|Bacteroidetes	C	ankyrin repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9952449_1	313606.M23134_05106	3.265e-42	158.0	COG1733@1|root,COG1733@2|Bacteria,4NQ5S@976|Bacteroidetes,47QMW@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
WH2_k127_9959184_2	1158294.JOMI01000007_gene486	4.115e-12	67.0	COG1670@1|root,COG1670@2|Bacteria,4NQB5@976|Bacteroidetes,2FTXH@200643|Bacteroidia	976|Bacteroidetes	J	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WH2_k127_9959184_1	765913.ThidrDRAFT_3025	3.898e-62	230.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,1RRGY@1236|Gammaproteobacteria,1WVVW@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
WH2_k127_9959184_0	1123278.KB893388_gene5749	1.287e-117	392.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,47NYU@768503|Cytophagia	976|Bacteroidetes	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
WH2_k127_9968896_1	313606.M23134_07225	1.249e-151	495.0	COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes,47MT8@768503|Cytophagia	976|Bacteroidetes	Q	phytoene	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
WH2_k127_9968896_2	926562.Oweho_0839	5.096e-44	181.0	COG2849@1|root,COG2849@2|Bacteria,4NW92@976|Bacteroidetes,1IKDQ@117743|Flavobacteriia,2PAPB@246874|Cryomorphaceae	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9968896_3	1279009.ADICEAN_02215	1.589e-28	134.0	COG3172@1|root,COG3172@2|Bacteria,4NFNZ@976|Bacteroidetes,47QMU@768503|Cytophagia	976|Bacteroidetes	H	ATPase kinase involved in NAD metabolism	nadR	-	-	-	-	-	-	-	-	-	-	-	AAA_28
WH2_k127_9968896_4	398767.Glov_3593	5.074e-27	117.0	COG1708@1|root,COG1708@2|Bacteria,1N97U@1224|Proteobacteria,42TTD@68525|delta/epsilon subdivisions,2WQUK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Nucleotidyltransferase substrate binding protein like	-	-	-	-	-	-	-	-	-	-	-	-	NTase_sub_bind
WH2_k127_9968896_5	401053.AciPR4_3811	6.146e-15	78.0	COG0034@1|root,COG0034@2|Bacteria,3Y3RG@57723|Acidobacteria,2JHXM@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
WH2_k127_9968896_0	1166018.FAES_5474	3.874e-186	601.0	COG1629@1|root,COG4771@2|Bacteria,4NEHN@976|Bacteroidetes,47Y82@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WH2_k127_9981333_1	1317122.ATO12_04640	2.759e-59	209.0	COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,1I1AE@117743|Flavobacteriia,2YHK5@290174|Aquimarina	976|Bacteroidetes	F	MafB19-like deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
WH2_k127_9981333_0	445970.ALIPUT_02234	4.742e-135	451.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,2FP0Y@200643|Bacteroidia,22U7G@171550|Rikenellaceae	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
WH2_k127_9985868_1	1223521.BBJX01000001_gene916	3.475e-27	116.0	2EUX4@1|root,33NCF@2|Bacteria,1NHD0@1224|Proteobacteria,2VZ14@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9985868_0	314264.ROS217_14566	6.626e-42	171.0	COG2931@1|root,COG3204@1|root,COG3386@1|root,COG5295@1|root,COG2931@2|Bacteria,COG3204@2|Bacteria,COG3386@2|Bacteria,COG5295@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,46P2B@74030|Roseovarius	28211|Alphaproteobacteria	MQ	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,HemolysinCabind,Laminin_G_3,PA14
WH2_k127_9986474_3	742725.HMPREF9450_00859	3.275e-13	80.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,22UVQ@171550|Rikenellaceae	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
WH2_k127_9986474_1	504472.Slin_1395	4.916e-47	183.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,47QER@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
WH2_k127_9986474_2	929556.Solca_0296	2.251e-16	83.0	COG2919@1|root,COG2919@2|Bacteria,4NURQ@976|Bacteroidetes,1IU2I@117747|Sphingobacteriia	976|Bacteroidetes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
WH2_k127_9986474_0	1122179.KB890450_gene4567	2.257e-75	256.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
WH2_k127_9994403_2	927658.AJUM01000034_gene301	5.015e-05	54.0	COG4704@1|root,COG4704@2|Bacteria,4NUMP@976|Bacteroidetes,2G1EU@200643|Bacteroidia,3XM0J@558415|Marinilabiliaceae	976|Bacteroidetes	S	Fibrobacter succinogenes major domain (Fib_succ_major)	-	-	-	-	-	-	-	-	-	-	-	-	BACON,Fib_succ_major
WH2_k127_9994403_0	1121957.ATVL01000007_gene2342	3.191e-14	84.0	COG3595@1|root,COG3595@2|Bacteria,4PMD5@976|Bacteroidetes,47SA4@768503|Cytophagia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
WH2_k127_9994403_1	1121875.KB907552_gene234	1.525e-08	60.0	28I9R@1|root,2Z8CE@2|Bacteria,4NE54@976|Bacteroidetes,1HWWD@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
WH2_k127_9997949_0	468059.AUHA01000003_gene1438	1.088e-148	490.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1INVI@117747|Sphingobacteriia	976|Bacteroidetes	D	DNA segregation ATPase FtsK SpoIIIE and related	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WH2_k127_9997949_2	755732.Fluta_0518	7.135e-21	101.0	2A8FU@1|root,30XHS@2|Bacteria,4PAYV@976|Bacteroidetes,1ICSJ@117743|Flavobacteriia,2PC02@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH2_k127_9997949_1	45351.EDO26796	4.992e-83	286.0	COG0010@1|root,KOG2965@2759|Eukaryota,38CCH@33154|Opisthokonta,3BCCT@33208|Metazoa	33208|Metazoa	E	arginase activity	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
## 2495 queries scanned
## Total time (seconds): 44.438639640808105
## Rate: 56.14 q/s