## Tue Dec 16 14:27:35 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/WH3_bin.23.fa -m mmseqs --itype genome -o WH3_bin.23 --output_dir /data/result/bins/wyx/egg/WH3_bin.23 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
WH3_k127_1000145_0	665571.STHERM_c19780	8.845e-175	556.0	COG0014@1|root,COG0014@2|Bacteria,2J5JS@203691|Spirochaetes	203691|Spirochaetes	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WH3_k127_10007243_1	1201290.M902_1884	5.549e-14	77.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,43AFB@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppB	-	-	ko:K02033,ko:K15585	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WH3_k127_10007243_0	862908.BMS_0153	6.771e-48	183.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,42Z5J@68525|delta/epsilon subdivisions,2X7Z6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
WH3_k127_10020025_1	247490.KSU1_D0541	4.917e-11	68.0	2EDD9@1|root,3379K@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3568)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3568
WH3_k127_10020025_0	335543.Sfum_1921	1.286e-152	491.0	COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,42MVP@68525|delta/epsilon subdivisions,2WITG@28221|Deltaproteobacteria,2MQZZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Ala_racemase_N,Orn_DAP_Arg_deC
WH3_k127_10028041_0	521674.Plim_2449	4.539e-150	501.0	COG0557@1|root,COG0557@2|Bacteria,2IX1J@203682|Planctomycetes	203682|Planctomycetes	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
WH3_k127_10028041_2	1142394.PSMK_22390	7.486e-14	74.0	COG0268@1|root,COG0268@2|Bacteria	2|Bacteria	J	rRNA binding	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
WH3_k127_10028041_1	1142394.PSMK_01490	1.285e-45	183.0	COG0457@1|root,COG0457@2|Bacteria	1142394.PSMK_01490|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10055863_0	926549.KI421517_gene1530	1.158e-97	330.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,47JNX@768503|Cytophagia	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WH3_k127_10055863_1	247490.KSU1_D0823	5.142e-20	96.0	COG0284@1|root,COG0284@2|Bacteria,2IXSF@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
WH3_k127_10056964_1	243090.RB588	5.874e-29	117.0	COG0551@1|root,COG3507@1|root,COG0551@2|Bacteria,COG3507@2|Bacteria,2J27X@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10056964_0	1195236.CTER_4445	2.064e-70	251.0	COG4409@1|root,COG4412@1|root,COG4409@2|Bacteria,COG4412@2|Bacteria,1TTSA@1239|Firmicutes,25BHE@186801|Clostridia,3WGF9@541000|Ruminococcaceae	186801|Clostridia	M	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
WH3_k127_10064512_0	1120954.ATXE01000001_gene2258	1.523e-38	151.0	COG0730@1|root,COG0730@2|Bacteria,2GK5W@201174|Actinobacteria	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WH3_k127_10090938_1	644282.Deba_2352	3.945e-09	69.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,42MHW@68525|delta/epsilon subdivisions,2WINK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
WH3_k127_10090938_0	73044.JNXP01000021_gene2555	1.689e-15	89.0	2FB4K@1|root,343AZ@2|Bacteria,2IN2Y@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10113456_1	877455.Metbo_0675	4.683e-10	62.0	arCOG04899@1|root,arCOG04899@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10113456_0	768671.ThimaDRAFT_4074	9.116e-122	404.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,1WXB9@135613|Chromatiales	135613|Chromatiales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
WH3_k127_10117851_0	394503.Ccel_2428	5.579e-108	362.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,36E1H@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
WH3_k127_10117851_1	523850.TON_1139	6.794e-24	112.0	COG0082@1|root,arCOG04133@2157|Archaea,2XT26@28890|Euryarchaeota,2437U@183968|Thermococci	183968|Thermococci	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
WH3_k127_10124915_0	56780.SYN_02211	1.043e-44	167.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
WH3_k127_10124915_1	644282.Deba_1149	5.017e-36	145.0	2BCS0@1|root,303C3@2|Bacteria,1N7SU@1224|Proteobacteria,42WF2@68525|delta/epsilon subdivisions,2WR6I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
WH3_k127_10134989_0	247490.KSU1_C1273	6.66e-96	323.0	COG3408@1|root,COG3408@2|Bacteria,2IYTX@203682|Planctomycetes	203682|Planctomycetes	G	Glycogen debranching enzyme N terminal	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
WH3_k127_10134989_1	1142394.PSMK_29610	1.337e-56	208.0	COG1234@1|root,COG1234@2|Bacteria,2IWSW@203682|Planctomycetes	203682|Planctomycetes	S	of the beta-lactamase	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
WH3_k127_10163978_1	1123242.JH636437_gene6144	1.519e-34	137.0	COG2204@1|root,COG2204@2|Bacteria,2IWYY@203682|Planctomycetes	203682|Planctomycetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WH3_k127_10163978_0	1210884.HG799469_gene13944	4.296e-38	147.0	COG0542@1|root,COG0542@2|Bacteria,2IXHI@203682|Planctomycetes	203682|Planctomycetes	O	with chaperone activity ATP-binding	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
WH3_k127_10163978_2	237368.SCABRO_01587	9.306e-23	107.0	COG1262@1|root,COG1262@2|Bacteria,2IXQ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FGE-sulfatase,TPR_11
WH3_k127_10188531_0	1201288.M900_0578	1.064e-37	149.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,42Z5J@68525|delta/epsilon subdivisions,2X7Z6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
WH3_k127_10188759_0	331113.SNE_B24410	8.043e-149	479.0	COG0058@1|root,COG0058@2|Bacteria,2JFEH@204428|Chlamydiae	204428|Chlamydiae	G	Carbohydrate phosphorylase	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
WH3_k127_10188759_1	411463.EUBVEN_00667	7.275e-20	98.0	COG3584@1|root,COG3584@2|Bacteria,1VGG7@1239|Firmicutes,25NR6@186801|Clostridia,25XCK@186806|Eubacteriaceae	186801|Clostridia	N	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
WH3_k127_10207262_0	344747.PM8797T_09414	1.549e-09	63.0	COG4972@1|root,COG4972@2|Bacteria,2IZC6@203682|Planctomycetes	203682|Planctomycetes	NU	pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
WH3_k127_10207262_1	314230.DSM3645_24265	3.603e-07	59.0	COG4970@1|root,COG4970@2|Bacteria,2J1P5@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
WH3_k127_10207862_1	314230.DSM3645_28657	1.452e-57	204.0	COG0353@1|root,COG0353@2|Bacteria,2IXK5@203682|Planctomycetes	203682|Planctomycetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
WH3_k127_10207862_0	886293.Sinac_1310	2.493e-98	345.0	COG2812@1|root,COG2812@2|Bacteria,2IX1M@203682|Planctomycetes	203682|Planctomycetes	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
WH3_k127_10233056_0	1469948.JPNB01000002_gene2931	1.413e-17	91.0	COG1595@1|root,COG1595@2|Bacteria,1VC8N@1239|Firmicutes,24AUU@186801|Clostridia,36H0U@31979|Clostridiaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH3_k127_10233056_1	889378.Spiaf_2507	0.0001665	45.0	COG0401@1|root,COG0401@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	Pmp3
WH3_k127_10237942_1	402777.KB235898_gene4978	1.064e-17	94.0	COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria,1G463@1117|Cyanobacteria,1H97Y@1150|Oscillatoriales	1117|Cyanobacteria	MQ	PFAM Collagen-binding surface protein Cna-like, B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,SdrD_B
WH3_k127_10237942_0	1142394.PSMK_30020	7.072e-50	189.0	COG1192@1|root,COG3170@1|root,COG1192@2|Bacteria,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496,ko:K09000	-	-	-	-	ko00000,ko02048,ko03036,ko04812	-	-	-	AAA_31
WH3_k127_10241530_0	1166018.FAES_3984	1.241e-40	166.0	COG4653@1|root,COG4653@2|Bacteria,4NUPP@976|Bacteroidetes,47SEM@768503|Cytophagia	976|Bacteroidetes	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
WH3_k127_10242827_0	247490.KSU1_C1340	7.136e-115	381.0	COG0016@1|root,COG0016@2|Bacteria,2IXSW@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
WH3_k127_10242827_1	428125.CLOLEP_03301	7.976e-28	116.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,3WIYY@541000|Ruminococcaceae	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
WH3_k127_10242827_3	522772.Dacet_1960	2.676e-08	57.0	COG0291@1|root,COG0291@2|Bacteria,2GFY3@200930|Deferribacteres	200930|Deferribacteres	J	Ribosomal protein L35	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
WH3_k127_10242827_2	1294142.CINTURNW_1371	1.971e-21	97.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,36I2Z@31979|Clostridiaceae	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
WH3_k127_10248602_0	886293.Sinac_1564	2.285e-196	630.0	COG0568@1|root,COG0568@2|Bacteria,2IXI3@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WH3_k127_10253356_0	756272.Plabr_0466	3.436e-182	579.0	COG0439@1|root,COG0439@2|Bacteria,2IWZV@203682|Planctomycetes	203682|Planctomycetes	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
WH3_k127_10253356_4	583355.Caka_1863	1.101e-35	140.0	COG0511@1|root,COG0511@2|Bacteria,46SXA@74201|Verrucomicrobia,3K861@414999|Opitutae	414999|Opitutae	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
WH3_k127_10253356_3	290512.Paes_2294	1.103e-40	154.0	COG0735@1|root,COG0735@2|Bacteria	2|Bacteria	P	belongs to the Fur family	fur	-	-	ko:K03711,ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
WH3_k127_10253356_1	1347392.CCEZ01000008_gene2229	4.865e-96	323.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,249VZ@186801|Clostridia,36EYU@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
WH3_k127_10253356_2	316067.Geob_0044	3.871e-77	265.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2WKMZ@28221|Deltaproteobacteria,43U5P@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PFAM ABC transporter related	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
WH3_k127_10253412_0	478741.JAFS01000002_gene304	1.01e-32	138.0	COG1044@1|root,COG1044@2|Bacteria,46V34@74201|Verrucomicrobia	74201|Verrucomicrobia	M	SpoIVB peptidase S55	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
WH3_k127_10267173_0	483219.LILAB_14885	4.671e-28	123.0	COG3394@1|root,COG3394@2|Bacteria,1MX3P@1224|Proteobacteria,42TZT@68525|delta/epsilon subdivisions,2WQ2A@28221|Deltaproteobacteria,2YYV7@29|Myxococcales	28221|Deltaproteobacteria	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
WH3_k127_10267173_1	1123354.AUDR01000017_gene15	2.014e-10	71.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2VH76@28216|Betaproteobacteria,1KRXW@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
WH3_k127_10288112_1	243233.MCA0196	3.008e-45	167.0	COG1371@1|root,COG1371@2|Bacteria,1RJU0@1224|Proteobacteria,1S8F6@1236|Gammaproteobacteria,1XFH0@135618|Methylococcales	135618|Methylococcales	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
WH3_k127_10288112_0	472759.Nhal_1884	2.014e-190	607.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1WZYK@135613|Chromatiales	135613|Chromatiales	H	Belongs to the RtcB family	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
WH3_k127_10289291_0	420246.GTNG_2960	1.327e-48	188.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli,1WFW5@129337|Geobacillus	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU32840	3HCDH,3HCDH_N,ECH_1
WH3_k127_10309866_4	335543.Sfum_1841	5.207e-10	63.0	COG0502@1|root,COG0502@2|Bacteria,1MXK0@1224|Proteobacteria,42Q6J@68525|delta/epsilon subdivisions,2WKXA@28221|Deltaproteobacteria,2MR5K@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Biotin and Thiamin Synthesis associated	-	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
WH3_k127_10309866_2	1121459.AQXE01000005_gene1545	1.845e-21	102.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,42UF8@68525|delta/epsilon subdivisions,2WR6W@28221|Deltaproteobacteria,2MBZF@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
WH3_k127_10309866_1	1380358.JADJ01000010_gene429	4.719e-23	101.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XM5A@135619|Oceanospirillales	135619|Oceanospirillales	K	cold-shock protein	cspG	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WH3_k127_10309866_3	1128398.Curi_c16700	1.665e-14	79.0	COG1633@1|root,COG1633@2|Bacteria,1VD5Y@1239|Firmicutes,24MPV@186801|Clostridia	186801|Clostridia	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
WH3_k127_10309866_0	1499967.BAYZ01000073_gene2040	5.928e-50	182.0	COG0673@1|root,COG0673@2|Bacteria,2NQRC@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WH3_k127_10311873_0	926550.CLDAP_26280	9.864e-34	143.0	COG1609@1|root,COG1609@2|Bacteria,2G855@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WH3_k127_10345936_1	439235.Dalk_3029	2.994e-24	105.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,42M5P@68525|delta/epsilon subdivisions,2WM1R@28221|Deltaproteobacteria,2MID5@213118|Desulfobacterales	28221|Deltaproteobacteria	KL	SNF2 Helicase protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
WH3_k127_10345936_0	1142394.PSMK_22380	4.547e-30	125.0	COG0472@1|root,COG0472@2|Bacteria,2IXZQ@203682|Planctomycetes	203682|Planctomycetes	M	UDP-N-acetylmuramyl pentapeptide	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
WH3_k127_1035126_3	234267.Acid_2068	3.286e-23	106.0	COG1609@1|root,COG1609@2|Bacteria,3Y2ZZ@57723|Acidobacteria	57723|Acidobacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_3
WH3_k127_1035126_0	880073.Calab_1185	1.005e-253	811.0	COG0013@1|root,COG0013@2|Bacteria,2NNYC@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WH3_k127_1035126_1	1142394.PSMK_01740	3.559e-139	451.0	COG0468@1|root,COG0468@2|Bacteria,2IX4U@203682|Planctomycetes	203682|Planctomycetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
WH3_k127_1035126_2	386456.JQKN01000008_gene1415	2.085e-29	124.0	COG1514@1|root,arCOG01736@2157|Archaea,2XZ2M@28890|Euryarchaeota,23P6A@183925|Methanobacteria	183925|Methanobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
WH3_k127_1035126_4	502025.Hoch_6330	7.118e-12	67.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,2YU0F@29|Myxococcales	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
WH3_k127_10354899_1	309807.SRU_1584	3.3e-05	57.0	COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,1FJ24@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
WH3_k127_10354899_0	66874.JOFS01000006_gene4304	1.124e-07	53.0	COG4274@1|root,COG4274@2|Bacteria,2IJ0R@201174|Actinobacteria	201174|Actinobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
WH3_k127_10424667_1	313628.LNTAR_09369	2.022e-47	188.0	COG2503@1|root,COG2503@2|Bacteria	2|Bacteria	M	HAD superfamily, subfamily IIIB (Acid phosphatase)	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10441976_0	614083.AWQR01000014_gene2398	2.873e-35	154.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,2VH1Y@28216|Betaproteobacteria,4AAUG@80864|Comamonadaceae	28216|Betaproteobacteria	CP	NADH Ubiquinone plastoquinone (Complex I)	phaD	-	-	ko:K05561	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	Proton_antipo_M
WH3_k127_10443708_0	886293.Sinac_6812	3.279e-95	331.0	COG1480@1|root,COG1480@2|Bacteria,2IYP7@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
WH3_k127_10451540_2	1123242.JH636434_gene4769	8.456e-14	72.0	COG0439@1|root,COG0439@2|Bacteria,2IWZV@203682|Planctomycetes	203682|Planctomycetes	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
WH3_k127_10451540_0	886293.Sinac_6401	1.958e-89	308.0	COG0758@1|root,COG1948@1|root,COG0758@2|Bacteria,COG1948@2|Bacteria,2IX3D@203682|Planctomycetes	203682|Planctomycetes	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
WH3_k127_10451540_1	1449049.JONW01000011_gene2279	1.557e-23	109.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
WH3_k127_10454275_2	671143.DAMO_2322	5.721e-38	148.0	COG2865@1|root,COG2865@2|Bacteria,2NRI7@2323|unclassified Bacteria	2|Bacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,DUF4365,HATPase_c_4
WH3_k127_10454275_1	237368.SCABRO_00204	5.277e-48	181.0	COG1386@1|root,COG1386@2|Bacteria,2IZNB@203682|Planctomycetes	203682|Planctomycetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
WH3_k127_10454275_0	264462.Bd1058	3.57e-55	199.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,42NB7@68525|delta/epsilon subdivisions,2MTXI@213481|Bdellovibrionales,2WNTJ@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
WH3_k127_10458934_0	575540.Isop_2875	1.144e-127	416.0	COG4864@1|root,COG4864@2|Bacteria,2IXDK@203682|Planctomycetes	203682|Planctomycetes	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
WH3_k127_10458934_1	1142394.PSMK_30750	1.124e-17	89.0	COG1030@1|root,COG1030@2|Bacteria,2J0K3@203682|Planctomycetes	203682|Planctomycetes	O	Membrane-bound serine protease (ClpP class)	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
WH3_k127_10458934_2	649638.Trad_0448	1.245e-11	66.0	COG1030@1|root,COG1030@2|Bacteria,1WIAJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
WH3_k127_1046334_0	518766.Rmar_1459	5.016e-152	496.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1FIMN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WH3_k127_1046334_1	1408813.AYMG01000012_gene1057	0.0006697	45.0	COG3254@1|root,COG3420@1|root,COG3254@2|Bacteria,COG3420@2|Bacteria,4NF5Y@976|Bacteroidetes,1IQQQ@117747|Sphingobacteriia	976|Bacteroidetes	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,rhaM
WH3_k127_10516907_2	886293.Sinac_5362	1.891e-93	321.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2IXQR@203682|Planctomycetes	203682|Planctomycetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WH3_k127_10516907_0	314282.PCNPT3_07895	3.216e-163	533.0	COG4146@1|root,COG4146@2|Bacteria,1MXWV@1224|Proteobacteria,1RR4S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	sglT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
WH3_k127_10516907_1	81824.XP_001749217.1	5.748e-162	520.0	COG0153@1|root,COG1095@1|root,KOG0631@2759|Eukaryota,KOG3297@2759|Eukaryota,397U9@33154|Opisthokonta	33154|Opisthokonta	K	transcription initiation from RNA polymerase III promoter	POLR3H	GO:0000228,GO:0000428,GO:0000785,GO:0000790,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005666,GO:0005694,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0006139,GO:0006351,GO:0006352,GO:0006383,GO:0006384,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009304,GO:0009987,GO:0010467,GO:0015630,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0042797,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0046483,GO:0055029,GO:0061695,GO:0070013,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0098781,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	-	ko:K03022	ko00230,ko00240,ko01100,ko03020,ko04623,ko05169,map00230,map00240,map01100,map03020,map04623,map05169	M00181	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko03021	-	-	-	RNA_pol_Rbc25,SHS2_Rpb7-N
WH3_k127_10516907_3	1185876.BN8_01714	4.286e-67	233.0	COG1387@1|root,COG1387@2|Bacteria,4NMBC@976|Bacteroidetes,47PG3@768503|Cytophagia	976|Bacteroidetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
WH3_k127_10528314_0	886293.Sinac_4410	4.366e-63	221.0	COG1132@1|root,COG1132@2|Bacteria,2IYCU@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase and permease	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
WH3_k127_10528314_1	1502770.JQMG01000001_gene1470	2.455e-43	168.0	COG1216@1|root,COG1216@2|Bacteria,1NC31@1224|Proteobacteria,2W82U@28216|Betaproteobacteria,2KNIZ@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH3_k127_10528314_2	555779.Dthio_PD1364	3.213e-23	115.0	COG3642@1|root,COG3642@2|Bacteria,1QXJZ@1224|Proteobacteria,43D2P@68525|delta/epsilon subdivisions,2X89V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
WH3_k127_10575684_0	1142394.PSMK_14720	1.281e-67	236.0	COG0548@1|root,COG0548@2|Bacteria,2IWVV@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
WH3_k127_10579400_0	243090.RB3871	2.125e-102	346.0	COG3385@1|root,COG3385@2|Bacteria,2IZDT@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS4 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WH3_k127_10579400_1	344747.PM8797T_06687	6.279e-09	59.0	COG1943@1|root,COG1943@2|Bacteria,2IYXS@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
WH3_k127_10579400_2	1123508.JH636444_gene5599	2.631e-07	55.0	COG3385@1|root,COG3385@2|Bacteria,2IYW8@203682|Planctomycetes	203682|Planctomycetes	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WH3_k127_10581043_0	891968.Anamo_1244	7.722e-69	236.0	COG0428@1|root,COG0428@2|Bacteria,3T9UW@508458|Synergistetes	508458|Synergistetes	P	PFAM zinc iron permease	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
WH3_k127_10581043_2	330214.NIDE0571	1.226e-51	185.0	COG3169@1|root,COG3169@2|Bacteria	2|Bacteria	S	Protein conserved in bacteria	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
WH3_k127_10581043_1	1121933.AUHH01000046_gene2364	1.073e-52	200.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4DNXK@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
WH3_k127_10581043_3	1125863.JAFN01000001_gene979	7.421e-06	57.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,42NBB@68525|delta/epsilon subdivisions,2WIMD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM ResB family protein	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
WH3_k127_10581043_4	1121936.AUHI01000013_gene1151	0.0007658	47.0	COG0755@1|root,COG0755@2|Bacteria,1TQZ4@1239|Firmicutes,4HA2N@91061|Bacilli	91061|Bacilli	O	cytochrome c biogenesis	resC	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
WH3_k127_10600606_0	1121289.JHVL01000036_gene2591	1.844e-18	88.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,36E5T@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
WH3_k127_10609496_0	1173263.Syn7502_01256	6.881e-10	68.0	COG2374@1|root,COG2931@1|root,COG3391@1|root,COG2374@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,1G0YK@1117|Cyanobacteria	1117|Cyanobacteria	K	phosphatase	-	-	3.1.3.8	ko:K01083,ko:K07004	ko00562,map00562	-	R03371	RC00078	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Calx-beta,DUF4114,Exo_endo_phos,LTD,Phytase-like
WH3_k127_10623119_0	479432.Sros_4614	5.549e-62	233.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4EG08@85012|Streptosporangiales	201174|Actinobacteria	M	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TIR_2,WD40
WH3_k127_1063398_1	247490.KSU1_C0729	2.382e-46	182.0	COG0616@1|root,COG0616@2|Bacteria,2IYKF@203682|Planctomycetes	203682|Planctomycetes	OU	TIGRFAM signal peptide peptidase SppA, 36K type	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
WH3_k127_1063398_0	479434.Sthe_1363	7.547e-61	223.0	COG0299@1|root,COG0299@2|Bacteria,2G6ZJ@200795|Chloroflexi,27Y8N@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
WH3_k127_1063398_2	644966.Tmar_2073	2.188e-31	136.0	COG0328@1|root,COG0328@2|Bacteria,1VAJW@1239|Firmicutes,24NJ8@186801|Clostridia	186801|Clostridia	L	PFAM ribonuclease H	rnhA	-	3.1.26.4	ko:K03469,ko:K06864	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
WH3_k127_1063398_3	1142394.PSMK_06010	1.199e-19	98.0	COG1579@1|root,COG1579@2|Bacteria	2|Bacteria	-	-	CP_0228	-	3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	zf-RING_7
WH3_k127_10659138_1	1121374.KB891592_gene2940	1.481e-25	112.0	COG3322@1|root,COG4191@1|root,COG3322@2|Bacteria,COG4191@2|Bacteria,1NVWZ@1224|Proteobacteria	1224|Proteobacteria	T	sensor, signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c
WH3_k127_10659138_0	296591.Bpro_4825	1.261e-53	205.0	COG0745@1|root,COG0784@1|root,COG2204@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,4AJX3@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE8,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
WH3_k127_10666403_0	1121468.AUBR01000019_gene2617	6.001e-93	319.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,42F14@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
WH3_k127_10677309_0	1396141.BATP01000002_gene4837	2.015e-61	229.0	COG3828@1|root,COG3828@2|Bacteria,46V1D@74201|Verrucomicrobia,2IUS0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
WH3_k127_10677309_1	530564.Psta_2420	1.591e-05	47.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WH3_k127_10688278_0	497964.CfE428DRAFT_1748	2.428e-78	265.0	COG3392@1|root,COG3392@2|Bacteria,46WWM@74201|Verrucomicrobia	74201|Verrucomicrobia	H	PFAM D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K07318	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MethyltransfD12
WH3_k127_10688278_1	555079.Toce_0386	1.22e-72	254.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,42FCT@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM PP-loop domain protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
WH3_k127_10710509_0	1408418.JNJH01000003_gene2304	7.625e-26	108.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2TQR5@28211|Alphaproteobacteria,2JPEF@204441|Rhodospirillales	204441|Rhodospirillales	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
WH3_k127_10710509_1	765911.Thivi_0253	1.278e-17	90.0	2CH72@1|root,32ZK4@2|Bacteria,1N8YD@1224|Proteobacteria,1SCY7@1236|Gammaproteobacteria,1WYDM@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2878)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2878
WH3_k127_1071649_0	240016.ABIZ01000001_gene277	1.836e-06	58.0	COG0265@1|root,COG0265@2|Bacteria,46SZ1@74201|Verrucomicrobia,2ITZC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
WH3_k127_10735301_6	1045854.WKK_05710	1.345e-11	66.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,4AX2U@81850|Leuconostocaceae	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
WH3_k127_10735301_4	868595.Desca_1282	5.714e-49	180.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,25ZXR@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
WH3_k127_10735301_5	1123242.JH636434_gene5388	3.007e-14	74.0	COG1758@1|root,COG1758@2|Bacteria,2J0KS@203682|Planctomycetes	203682|Planctomycetes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
WH3_k127_10735301_3	1121472.AQWN01000003_gene1425	9.488e-52	188.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,261KT@186807|Peptococcaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
WH3_k127_10735301_2	344747.PM8797T_01624	5.678e-54	204.0	COG1561@1|root,COG1561@2|Bacteria,2IYZH@203682|Planctomycetes	203682|Planctomycetes	S	stress-induced protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
WH3_k127_10735301_7	344747.PM8797T_01619	4.61e-09	63.0	COG1314@1|root,COG1314@2|Bacteria,2J0NU@203682|Planctomycetes	203682|Planctomycetes	U	PFAM Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
WH3_k127_10735301_1	246194.CHY_0282	2.121e-82	281.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,42FAI@68295|Thermoanaerobacterales	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
WH3_k127_10735301_0	1142394.PSMK_11990	2.036e-92	310.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,2IWZ7@203682|Planctomycetes	203682|Planctomycetes	E	chorismate mutase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
WH3_k127_10782260_0	1487921.DP68_11025	4.281e-50	186.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,36ES8@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS15830	Ala_racemase_C,Ala_racemase_N
WH3_k127_10782260_1	329726.AM1_2737	0.0005764	50.0	COG2105@1|root,COG2105@2|Bacteria,1GGD4@1117|Cyanobacteria	1117|Cyanobacteria	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
WH3_k127_10814741_0	575540.Isop_2452	1.07e-79	274.0	COG5525@1|root,COG5525@2|Bacteria,2IXN3@203682|Planctomycetes	203682|Planctomycetes	S	Phage terminase large subunit (GpA)	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_GpA
WH3_k127_10814741_2	395495.Lcho_2928	2.869e-05	48.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2VR9P@28216|Betaproteobacteria,1KKSD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
WH3_k127_10814741_1	290512.Paes_1736	4.066e-43	162.0	COG3177@1|root,COG3177@2|Bacteria,1FEFD@1090|Chlorobi	1090|Chlorobi	S	PFAM filamentation induced by cAMP protein Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
WH3_k127_10864923_2	886293.Sinac_3252	1.725e-05	53.0	2AE0U@1|root,313TG@2|Bacteria,2IZTR@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10864923_0	1122236.KB905141_gene1782	6.619e-37	154.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VJ2Y@28216|Betaproteobacteria,2KM6X@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	PFAM type II secretion system	-	-	-	ko:K12278	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
WH3_k127_10864923_1	754476.Q7A_1549	6.254e-06	59.0	COG1459@1|root,COG1459@2|Bacteria,1R68Y@1224|Proteobacteria,1S1WZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	PFAM Bacterial type II secretion system protein F domain	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
WH3_k127_10869869_2	1121405.dsmv_2042	7.463e-05	45.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,42M3M@68525|delta/epsilon subdivisions,2WJ8B@28221|Deltaproteobacteria,2MHUA@213118|Desulfobacterales	28221|Deltaproteobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
WH3_k127_10869869_1	1122216.AUHW01000001_gene652	9.449e-14	76.0	COG0375@1|root,COG0375@2|Bacteria,1VEP0@1239|Firmicutes,4H581@909932|Negativicutes	909932|Negativicutes	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
WH3_k127_10869869_0	1382306.JNIM01000001_gene188	5.2e-68	237.0	COG0378@1|root,COG0378@2|Bacteria,2G6EP@200795|Chloroflexi	200795|Chloroflexi	KO	Hydrogenase accessory protein HypB	hypB	-	-	ko:K03189,ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
WH3_k127_10877961_1	290633.GOX1430	4.371e-10	72.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,2JQVG@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WH3_k127_10877961_0	246197.MXAN_4908	4.628e-65	232.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria,2YVC9@29|Myxococcales	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
WH3_k127_10881607_1	765952.PUV_12510	7.586e-21	103.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,2JFPX@204428|Chlamydiae	204428|Chlamydiae	KLT	Together with the serine threonine kinase PknD, may play a role in the specific interactions with host proteins during intracellular growth	pkn1	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase
WH3_k127_10881607_2	1537994.JQFW01000057_gene264	2.974e-14	80.0	COG0070@1|root,COG0070@2|Bacteria,1NAKQ@1224|Proteobacteria,1SEQ8@1236|Gammaproteobacteria,46AJJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10881607_3	1121439.dsat_2883	2.439e-09	61.0	2EJF9@1|root,33D68@2|Bacteria,1NHKH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10881607_4	1121439.dsat_2883	0.0004742	44.0	2EJF9@1|root,33D68@2|Bacteria,1NHKH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_1090396_0	1142394.PSMK_16780	1.329e-82	287.0	COG1459@1|root,COG1459@2|Bacteria,2IXYZ@203682|Planctomycetes	203682|Planctomycetes	U	Type 4 fimbrial assembly protein pilC	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
WH3_k127_1090396_1	999541.bgla_1g01560	1.027e-27	117.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2VT48@28216|Betaproteobacteria,1K86T@119060|Burkholderiaceae	28216|Betaproteobacteria	U	Type II secretion system (T2SS), protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
WH3_k127_10906800_0	370438.PTH_1664	1.44e-35	150.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,2606F@186807|Peptococcaceae	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
WH3_k127_10928390_0	1201290.M902_1883	4.782e-74	260.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,42Z5J@68525|delta/epsilon subdivisions,2X7Z6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
WH3_k127_10958265_0	1492737.FEM08_09620	6.564e-129	425.0	COG1653@1|root,COG1653@2|Bacteria,4NG6U@976|Bacteroidetes	2|Bacteria	G	Pfam Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
WH3_k127_1097472_1	247490.KSU1_D0703	7.382e-84	294.0	COG0770@1|root,COG0770@2|Bacteria,2IXKX@203682|Planctomycetes	203682|Planctomycetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WH3_k127_1097472_0	1142394.PSMK_24980	6.015e-103	346.0	COG0472@1|root,COG0472@2|Bacteria,2IXU1@203682|Planctomycetes	203682|Planctomycetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
WH3_k127_10980261_2	1380763.BG53_07580	2.247e-55	203.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,26SEN@186822|Paenibacillaceae	91061|Bacilli	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
WH3_k127_10980261_1	1123288.SOV_3c02970	1.497e-80	272.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,4H44K@909932|Negativicutes	909932|Negativicutes	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
WH3_k127_10980261_0	1123253.AUBD01000012_gene970	1.195e-88	295.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,1X399@135614|Xanthomonadales	135614|Xanthomonadales	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WH3_k127_10987518_0	278963.ATWD01000001_gene2809	1.67e-14	80.0	COG1595@1|root,COG1595@2|Bacteria,3Y45G@57723|Acidobacteria,2JIQI@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH3_k127_11001045_0	1121091.AUMP01000001_gene199	1.265e-40	159.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli	91061|Bacilli	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
WH3_k127_11001045_1	1341151.ASZU01000004_gene331	9.735e-34	136.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,27BGU@186824|Thermoactinomycetaceae	91061|Bacilli	D	Cell cycle protein	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
WH3_k127_11009276_0	926562.Oweho_0880	2.019e-14	85.0	COG1361@1|root,COG3291@1|root,COG4935@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NGW4@976|Bacteroidetes,1IK8B@117743|Flavobacteriia	976|Bacteroidetes	O	Peptide-N-glycosidase F, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,N-glycanase_C
WH3_k127_11009276_1	160799.PBOR_29855	2.643e-13	82.0	COG1470@1|root,COG5434@1|root,COG5520@1|root,COG1470@2|Bacteria,COG5434@2|Bacteria,COG5520@2|Bacteria,1VC96@1239|Firmicutes,4HV2Q@91061|Bacilli,2774T@186822|Paenibacillaceae	91061|Bacilli	M	S-layer homology domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Big_4,CBM9_1,Pectate_lyase_3,SLH
WH3_k127_11057782_0	1304875.JAFZ01000001_gene1936	4.532e-44	167.0	COG1269@1|root,COG1269@2|Bacteria,3T9PG@508458|Synergistetes	508458|Synergistetes	U	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
WH3_k127_11057782_1	1499967.BAYZ01000145_gene6196	7.242e-35	139.0	COG0636@1|root,COG0636@2|Bacteria,2NRTJ@2323|unclassified Bacteria	2|Bacteria	U	ATP synthase subunit C	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110,ko:K02124	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157,M00159	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1,3.A.2.2,3.A.2.3	-	-	ATP-synt_C
WH3_k127_11057782_2	469381.Dpep_2112	4.272e-14	80.0	COG1390@1|root,COG1390@2|Bacteria,3TB57@508458|Synergistetes	508458|Synergistetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
WH3_k127_11062366_8	512564.MCRO_0139	1.812e-18	86.0	COG0199@1|root,COG0199@2|Bacteria,3WTWI@544448|Tenericutes	544448|Tenericutes	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
WH3_k127_11062366_1	537013.CLOSTMETH_00176	1.723e-65	228.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,3WGYQ@541000|Ruminococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
WH3_k127_11062366_6	360911.EAT1b_1622	3.484e-28	117.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,3WEZB@539002|Bacillales incertae sedis	91061|Bacilli	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
WH3_k127_11062366_3	1142394.PSMK_29080	5.888e-43	160.0	COG0093@1|root,COG0093@2|Bacteria,2IZMA@203682|Planctomycetes	203682|Planctomycetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
WH3_k127_11062366_7	1121878.AUGL01000033_gene2030	2.912e-19	89.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
WH3_k127_11062366_10	935948.KE386495_gene1504	5.777e-09	59.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,42H7J@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
WH3_k127_11062366_2	1142394.PSMK_29110	6.893e-51	184.0	COG0197@1|root,COG0197@2|Bacteria,2IZPH@203682|Planctomycetes	203682|Planctomycetes	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
WH3_k127_11062366_0	1142394.PSMK_29120	3.129e-75	261.0	COG0092@1|root,COG0092@2|Bacteria,2IWWU@203682|Planctomycetes	203682|Planctomycetes	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
WH3_k127_11062366_9	247490.KSU1_C1213	1.231e-17	89.0	COG0091@1|root,COG0091@2|Bacteria,2J023@203682|Planctomycetes	203682|Planctomycetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
WH3_k127_11062366_4	314230.DSM3645_09382	4.041e-36	138.0	COG0185@1|root,COG0185@2|Bacteria,2J0BB@203682|Planctomycetes	203682|Planctomycetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
WH3_k127_11062366_5	237368.SCABRO_03503	3.771e-31	124.0	COG0090@1|root,COG0090@2|Bacteria,2IXD9@203682|Planctomycetes	203682|Planctomycetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
WH3_k127_11071203_0	96561.Dole_1704	1.427e-30	132.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11082803_0	314230.DSM3645_07570	1.796e-103	348.0	COG0436@1|root,COG0436@2|Bacteria,2IY66@203682|Planctomycetes	203682|Planctomycetes	E	aminotransferase class I and II	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
WH3_k127_11088612_0	530564.Psta_2436	5.074e-138	453.0	COG1530@1|root,COG1530@2|Bacteria,2IWSS@203682|Planctomycetes	203682|Planctomycetes	J	TIGRFAM ribonuclease, Rne Rng family	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
WH3_k127_11088612_1	530564.Psta_0845	1.046e-78	274.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,2IX0R@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the SIS family. GutQ KpsF subfamily	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
WH3_k127_11088612_3	1232410.KI421421_gene3584	3.952e-44	166.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,42SN2@68525|delta/epsilon subdivisions,2WP0X@28221|Deltaproteobacteria,43SHS@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
WH3_k127_11088612_4	292564.Cyagr_0353	6.624e-43	159.0	COG0393@1|root,COG0393@2|Bacteria,1GHYX@1117|Cyanobacteria,22TX9@167375|Cyanobium	1117|Cyanobacteria	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
WH3_k127_11088612_2	1121918.ARWE01000001_gene2515	1.088e-77	269.0	COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,42RYA@68525|delta/epsilon subdivisions,2WNM0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterised protein family (UPF0014)	-	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
WH3_k127_11088612_5	1121918.ARWE01000001_gene2516	9.048e-42	162.0	COG1132@1|root,COG1132@2|Bacteria,1QXPT@1224|Proteobacteria	1224|Proteobacteria	V	Pfam ABC	-	-	-	ko:K02068	-	M00211	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
WH3_k127_11094903_0	1191523.MROS_0632	5.167e-65	237.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,dCache_1
WH3_k127_11116264_0	56780.SYN_00608	2.683e-229	718.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,2MQ6I@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
WH3_k127_11120925_0	574087.Acear_0203	3.257e-71	255.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1TQJM@1239|Firmicutes,24CFC@186801|Clostridia	186801|Clostridia	C	TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit	glpC	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
WH3_k127_11135538_0	247490.KSU1_B0716	5.677e-85	294.0	COG0187@1|root,COG0187@2|Bacteria,2IXF8@203682|Planctomycetes	203682|Planctomycetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WH3_k127_11135538_1	575540.Isop_0958	0.0008092	49.0	COG0457@1|root,COG0457@2|Bacteria,2J199@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
WH3_k127_11139798_4	931276.Cspa_c31080	9.872e-09	66.0	COG0457@1|root,COG0457@2|Bacteria,1UYZH@1239|Firmicutes,24BU9@186801|Clostridia,36F2E@31979|Clostridiaceae	186801|Clostridia	S	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
WH3_k127_11139798_1	204669.Acid345_4084	7.14e-106	349.0	COG1611@1|root,COG1611@2|Bacteria,3Y7Y0@57723|Acidobacteria,2JN31@204432|Acidobacteriia	204432|Acidobacteriia	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
WH3_k127_11139798_0	452637.Oter_0554	2.283e-196	621.0	COG1236@1|root,COG1236@2|Bacteria,46UFS@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
WH3_k127_11139798_2	1396141.BATP01000007_gene5758	1.339e-44	172.0	2C3WA@1|root,2Z8P1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
WH3_k127_11139798_3	1232410.KI421426_gene1481	7.025e-10	64.0	2DRBR@1|root,33B4T@2|Bacteria,1NHJT@1224|Proteobacteria,43EE5@68525|delta/epsilon subdivisions,2WSXG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
WH3_k127_11139798_5	909663.KI867149_gene3179	4.471e-07	51.0	COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,42PD2@68525|delta/epsilon subdivisions,2WJIK@28221|Deltaproteobacteria,2MR97@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SEC-C,SPASM
WH3_k127_11143212_0	243164.DET1092	1.718e-153	490.0	COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,2G9TE@200795|Chloroflexi	200795|Chloroflexi	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
WH3_k127_11143212_4	1216932.CM240_0611	1.719e-06	57.0	28IR9@1|root,2Z8QS@2|Bacteria,1TV6T@1239|Firmicutes,24AWB@186801|Clostridia,36GT7@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_4
WH3_k127_11143212_3	994573.T472_0211080	1.736e-43	162.0	COG1403@1|root,COG1403@2|Bacteria,1V7XZ@1239|Firmicutes,24JNG@186801|Clostridia,36IVP@31979|Clostridiaceae	186801|Clostridia	L	HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
WH3_k127_11143212_1	748727.CLJU_c03460	4.005e-51	184.0	COG1191@1|root,COG1191@2|Bacteria,1V5AE@1239|Firmicutes,24KF0@186801|Clostridia,36J5Y@31979|Clostridiaceae	186801|Clostridia	K	sigma factor activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1492
WH3_k127_11143212_2	498761.HM1_2943	3.877e-48	173.0	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia	186801|Clostridia	L	snf2 family	-	-	-	-	-	-	-	-	-	-	-	-	SNF2_N
WH3_k127_11152644_1	1121957.ATVL01000012_gene854	2.386e-112	375.0	COG1649@1|root,COG1649@2|Bacteria,4NJ45@976|Bacteroidetes,47JSI@768503|Cytophagia	976|Bacteroidetes	S	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
WH3_k127_11152644_0	234267.Acid_0712	2.746e-157	509.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	3.2.1.178,3.2.1.4	ko:K01179,ko:K20830	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH16,GH5,GH9	-	CBM_4_9,Glyco_hydro_16,RicinB_lectin_2
WH3_k127_11174427_0	1121405.dsmv_2856	1.859e-86	307.0	COG3039@1|root,COG3039@2|Bacteria,1PKUP@1224|Proteobacteria,43ECD@68525|delta/epsilon subdivisions,2X0BQ@28221|Deltaproteobacteria,2MP4F@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11176070_1	1121935.AQXX01000137_gene3908	9.792e-30	123.0	COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria,1XHAR@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate	pdxB	-	1.1.1.290	ko:K03473	ko00750,ko01100,map00750,map01100	M00124	R04210	RC00084	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C,DUF3410
WH3_k127_11176070_0	2340.JV46_03700	9.219e-74	257.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1J4XT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_3924,iPC815.YPO3501	Pterin_bind
WH3_k127_11182722_0	530564.Psta_4222	8.113e-110	366.0	COG0825@1|root,COG0825@2|Bacteria,2IX7N@203682|Planctomycetes	203682|Planctomycetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
WH3_k127_11182722_1	1191523.MROS_1561	4.458e-59	212.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	pdxB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.290	ko:K03473	ko00750,ko01100,map00750,map01100	M00124	R04210	RC00084	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z3582	2-Hacid_dh,2-Hacid_dh_C,DUF3410
WH3_k127_11182952_0	1121448.DGI_2643	9.679e-178	566.0	COG1861@1|root,COG1861@2|Bacteria,1QU5J@1224|Proteobacteria,43EAS@68525|delta/epsilon subdivisions,2X7TI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
WH3_k127_11192623_0	936574.HMPREF1508_1800	3.185e-51	190.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia	186801|Clostridia	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WH3_k127_1120124_0	247490.KSU1_C0320	1.43e-136	445.0	COG0539@1|root,COG0539@2|Bacteria,2IXPK@203682|Planctomycetes	203682|Planctomycetes	J	Ribosomal protein S1	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
WH3_k127_1120124_1	656519.Halsa_1544	8.178e-29	119.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3WA6D@53433|Halanaerobiales	186801|Clostridia	J	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
WH3_k127_11203463_0	1144275.COCOR_01443	7.03e-139	445.0	COG0842@1|root,COG0842@2|Bacteria,1MUIA@1224|Proteobacteria,43AEH@68525|delta/epsilon subdivisions,2WIU2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC-2 type transporter	yhhJ	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WH3_k127_11221627_0	237368.SCABRO_01933	9.496e-118	387.0	COG0034@1|root,COG0034@2|Bacteria,2IXKC@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
WH3_k127_11221627_1	1142394.PSMK_01400	1.05e-40	153.0	COG0150@1|root,COG0150@2|Bacteria,2IYCG@203682|Planctomycetes	203682|Planctomycetes	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WH3_k127_11227603_0	1128427.KB904821_gene563	4.266e-15	77.0	COG0606@1|root,COG0606@2|Bacteria,1G0K1@1117|Cyanobacteria,1H6YU@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM Magnesium chelatase, subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WH3_k127_11227603_1	1142394.PSMK_29770	4.691e-06	55.0	COG3023@1|root,COG3023@2|Bacteria,2J0EH@203682|Planctomycetes	203682|Planctomycetes	V	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
WH3_k127_11237234_2	671143.DAMO_2850	2.438e-12	66.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2NNRS@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.3.1.128,6.3.5.2	ko:K01951,ko:K03790	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002,ko03009	-	-	iJN746.PP_1032,iLJ478.TM1820,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833	GATase,GMP_synt_C,NAD_synthase
WH3_k127_11237234_1	237368.SCABRO_01038	1.564e-86	302.0	COG0845@1|root,COG0845@2|Bacteria,2J0F5@203682|Planctomycetes	203682|Planctomycetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
WH3_k127_11237234_0	404380.Gbem_1941	1.841e-107	354.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
WH3_k127_11241544_0	944547.ABLL_0287	1.943e-58	214.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria	1224|Proteobacteria	L	IS30 family	ISPlu1B	-	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
WH3_k127_11241544_1	1121899.Q764_13535	6.704e-06	49.0	2DH84@1|root,2ZYR5@2|Bacteria,4PDPQ@976|Bacteroidetes,1IE3Y@117743|Flavobacteriia,2NZTJ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11243101_0	530564.Psta_1482	9.012e-18	90.0	COG0526@1|root,COG0526@2|Bacteria,2J34G@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_8
WH3_k127_11261179_1	1142394.PSMK_19560	4.485e-77	277.0	COG4972@1|root,COG4972@2|Bacteria,2IWXB@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
WH3_k127_11261179_0	247490.KSU1_C0325	1.728e-84	296.0	COG0621@1|root,COG0621@2|Bacteria,2IXJS@203682|Planctomycetes	203682|Planctomycetes	J	SMART Elongator protein 3 MiaB NifB	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
WH3_k127_11268092_0	644548.SCNU_16853	4.331e-75	261.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,2GJ5U@201174|Actinobacteria,4GBNW@85026|Gordoniaceae	201174|Actinobacteria	C	belongs to the CobB CobQ family	pta	GO:0005575,GO:0005576	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
WH3_k127_11279858_0	760192.Halhy_1128	1.057e-39	160.0	COG3209@1|root,COG3209@2|Bacteria,4NFUE@976|Bacteroidetes,1INSI@117747|Sphingobacteriia	976|Bacteroidetes	M	COG3209 Rhs family protein	rhsA	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
WH3_k127_11320301_1	237368.SCABRO_01912	4.912e-07	59.0	2DVEZ@1|root,33VK5@2|Bacteria	2|Bacteria	S	Outer membrane protein (OmpH-like)	-	-	-	-	-	-	-	-	-	-	-	-	OmpH
WH3_k127_11320301_0	1210884.HG799462_gene8651	2.035e-36	147.0	COG4775@1|root,COG4775@2|Bacteria,2IWWA@203682|Planctomycetes	203682|Planctomycetes	M	Outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
WH3_k127_11323888_0	118168.MC7420_2911	3.966e-40	160.0	COG0500@1|root,COG0500@2|Bacteria,1G31R@1117|Cyanobacteria,1HCN2@1150|Oscillatoriales	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
WH3_k127_11333010_0	762903.Pedsa_0718	1.3e-78	272.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	plyA1	-	4.2.2.8	ko:K12547,ko:K19052	-	-	-	-	ko00000,ko01000	-	PL12	-	Beta_helix,Glyco_hydro_28,Pectate_lyase_3
WH3_k127_11333010_1	1968.JOEV01000013_gene871	3.704e-15	87.0	28NJG@1|root,30HV1@2|Bacteria,2GT1B@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11333010_2	1242864.D187_006851	1.761e-13	82.0	COG4733@1|root,COG4733@2|Bacteria,1R6EB@1224|Proteobacteria,430XN@68525|delta/epsilon subdivisions,2WW14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Starch binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM_20,CBM_25,fn3
WH3_k127_11333979_0	1120947.ATUX01000005_gene1302	3.172e-06	57.0	COG3347@1|root,COG3347@2|Bacteria,2HF07@201174|Actinobacteria,4D599@85005|Actinomycetales	201174|Actinobacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
WH3_k127_11354532_1	706587.Desti_3695	5.564e-44	164.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42MTH@68525|delta/epsilon subdivisions,2WJQY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WH3_k127_11354532_0	1380408.AVGH01000022_gene1817	8.768e-55	198.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,21WGJ@150247|Anoxybacillus	91061|Bacilli	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WH3_k127_11358857_0	756272.Plabr_2330	6.137e-54	201.0	COG0030@1|root,COG0030@2|Bacteria,2IYD7@203682|Planctomycetes	203682|Planctomycetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
WH3_k127_11365098_2	756272.Plabr_1999	6.216e-15	79.0	COG0394@1|root,COG0394@2|Bacteria,2IX5F@203682|Planctomycetes	203682|Planctomycetes	T	Belongs to the SUA5 family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc,Sua5_yciO_yrdC
WH3_k127_11365098_0	521674.Plim_2593	2.597e-44	165.0	COG0698@1|root,COG0698@2|Bacteria,2IZKI@203682|Planctomycetes	203682|Planctomycetes	G	COG0698 Ribose 5-phosphate isomerase RpiB	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
WH3_k127_11365098_1	247490.KSU1_C0635	5.793e-20	97.0	COG1361@1|root,COG1361@2|Bacteria,2IY9X@203682|Planctomycetes	203682|Planctomycetes	M	60 kDa outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
WH3_k127_11374455_1	1382358.JHVN01000015_gene595	0.0002749	50.0	COG0517@1|root,COG0517@2|Bacteria,1V9ZB@1239|Firmicutes,4HHZP@91061|Bacilli,21VQF@150247|Anoxybacillus	91061|Bacilli	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WH3_k127_11374455_0	1265505.ATUG01000002_gene2677	6.173e-34	145.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2MHZP@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase, homodimeric	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
WH3_k127_11386229_3	1403819.BATR01000125_gene4476	1.475e-17	84.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,DUF676,Hydrolase_4,PGAP1
WH3_k127_11386229_0	1304885.AUEY01000019_gene1167	6.002e-117	385.0	28HK0@1|root,2Z7V0@2|Bacteria,1MXSJ@1224|Proteobacteria,42P6V@68525|delta/epsilon subdivisions,2WM6M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
WH3_k127_11386229_1	593750.Metfor_2109	1.262e-77	262.0	COG2406@1|root,arCOG01093@2157|Archaea,2XWHS@28890|Euryarchaeota	28890|Euryarchaeota	S	COG2406 Protein distantly related to bacterial ferritins	dpsA2	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
WH3_k127_11386229_2	903818.KI912268_gene1318	3.777e-29	118.0	COG0702@1|root,COG0702@2|Bacteria,3Y7DF@57723|Acidobacteria	57723|Acidobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
WH3_k127_11395919_5	247490.KSU1_C0310	3.219e-16	81.0	COG3880@1|root,COG3880@2|Bacteria,2J09E@203682|Planctomycetes	203682|Planctomycetes	S	protein with conserved CXXC pairs	-	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
WH3_k127_11395919_0	1142394.PSMK_26160	4.015e-106	357.0	COG3869@1|root,COG3869@2|Bacteria,2IXJG@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
WH3_k127_11395919_2	1121451.DESAM_20489	3.381e-38	153.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,42TIP@68525|delta/epsilon subdivisions,2X5J4@28221|Deltaproteobacteria,2MGRS@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
WH3_k127_11395919_4	452637.Oter_4059	1.855e-22	101.0	COG0526@1|root,COG0526@2|Bacteria,46W21@74201|Verrucomicrobia	74201|Verrucomicrobia	CO	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WH3_k127_11395919_1	909663.KI867150_gene1425	3.764e-104	342.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria,2MS43@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
WH3_k127_11395919_3	269799.Gmet_0517	3.746e-23	106.0	COG0526@1|root,COG0526@2|Bacteria,1N0R9@1224|Proteobacteria,42UD9@68525|delta/epsilon subdivisions,2WQ0H@28221|Deltaproteobacteria,43VAC@69541|Desulfuromonadales	28221|Deltaproteobacteria	CO	PFAM Thioredoxin	trx-2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WH3_k127_11405143_0	1123373.ATXI01000023_gene1785	4.011e-90	309.0	COG0438@1|root,COG0438@2|Bacteria,2GHK9@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11423709_0	945713.IALB_2034	1.667e-129	424.0	COG0733@1|root,COG0733@2|Bacteria	2|Bacteria	S	neurotransmitter:sodium symporter activity	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
WH3_k127_11423709_1	1142394.PSMK_31090	5.145e-23	100.0	COG2159@1|root,COG2159@2|Bacteria,2IXTD@203682|Planctomycetes	203682|Planctomycetes	S	TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
WH3_k127_11461790_1	215803.DB30_5233	0.0001785	55.0	COG4733@1|root,COG4733@2|Bacteria,1QX65@1224|Proteobacteria,43BYR@68525|delta/epsilon subdivisions,2X79M@28221|Deltaproteobacteria,2YZ8E@29|Myxococcales	28221|Deltaproteobacteria	G	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
WH3_k127_11461790_0	1121904.ARBP01000023_gene4974	1.072e-21	111.0	COG5434@1|root,COG5492@1|root,COG5434@2|Bacteria,COG5492@2|Bacteria,4NIYD@976|Bacteroidetes	976|Bacteroidetes	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Pectate_lyase_3
WH3_k127_11510357_0	1123242.JH636434_gene4081	2.813e-162	520.0	COG0422@1|root,COG0422@2|Bacteria,2IWV7@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
WH3_k127_1151675_0	1379698.RBG1_1C00001G1870	3.829e-73	256.0	COG0232@1|root,COG0232@2|Bacteria,2NP3S@2323|unclassified Bacteria	2|Bacteria	F	Phosphohydrolase-associated domain	dgt	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
WH3_k127_1151675_1	608538.HTH_1545	5.804e-49	180.0	COG0537@1|root,COG0537@2|Bacteria,2G43E@200783|Aquificae	200783|Aquificae	FG	PFAM Histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
WH3_k127_1154939_0	1492737.FEM08_09670	1.485e-51	195.0	COG1649@1|root,COG1649@2|Bacteria,4NJ45@976|Bacteroidetes,1HZ0C@117743|Flavobacteriia,2NSG6@237|Flavobacterium	976|Bacteroidetes	S	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
WH3_k127_11588069_1	1235457.C404_26320	8.575e-05	52.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,1K0BI@119060|Burkholderiaceae	28216|Betaproteobacteria	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_2,Thioredoxin_7
WH3_k127_11588069_0	593750.Metfor_2109	5.059e-62	215.0	COG2406@1|root,arCOG01093@2157|Archaea,2XWHS@28890|Euryarchaeota	28890|Euryarchaeota	S	COG2406 Protein distantly related to bacterial ferritins	dpsA2	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
WH3_k127_11604071_0	1142394.PSMK_08290	1.668e-41	165.0	COG2199@1|root,COG2199@2|Bacteria	2|Bacteria	T	diguanylate cyclase activity	yeaP	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	GAF,GAF_2,GAF_3,GGDEF
WH3_k127_11614192_0	1408823.AXUS01000006_gene57	1.828e-17	87.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	pncA	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
WH3_k127_11614192_1	717605.Theco_0946	8.71e-10	66.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HRBT@91061|Bacilli,270V7@186822|Paenibacillaceae	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
WH3_k127_11625866_1	247490.KSU1_C1421	1.147e-19	90.0	COG3666@1|root,COG3666@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
WH3_k127_11625866_0	247490.KSU1_B0173	7.115e-61	218.0	COG0084@1|root,COG0535@1|root,COG0084@2|Bacteria,COG0535@2|Bacteria,2IZ3Q@203682|Planctomycetes	203682|Planctomycetes	L	COG0084 Mg-dependent DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
WH3_k127_11633214_0	1318628.MARLIPOL_02665	6.811e-33	132.0	COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SAQE@1236|Gammaproteobacteria,4699N@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	YbaK prolyl-tRNA synthetase associated	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
WH3_k127_11633214_1	243231.GSU0124	1.366e-25	116.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,43UT3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
WH3_k127_11645668_3	553973.CLOHYLEM_06315	2.437e-12	67.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,21YSR@1506553|Lachnoclostridium	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH3_k127_11645668_0	1396141.BATP01000059_gene2463	1.263e-107	355.0	COG0115@1|root,COG0115@2|Bacteria,46S9W@74201|Verrucomicrobia,2ITHT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WH3_k127_11645668_1	530564.Psta_3133	9.313e-56	208.0	COG0142@1|root,COG0142@2|Bacteria,2IXUE@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
WH3_k127_11645668_2	247490.KSU1_C1436	3.088e-29	128.0	28PW7@1|root,32EDN@2|Bacteria,2J3ED@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF3313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3313
WH3_k127_11684250_1	1123355.JHYO01000012_gene738	1.656e-56	204.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,2TTNQ@28211|Alphaproteobacteria,36XCV@31993|Methylocystaceae	28211|Alphaproteobacteria	Q	Methionine biosynthesis protein MetW	metW	-	-	-	-	-	-	-	-	-	-	-	MetW
WH3_k127_11684250_0	675812.VHA_002949	4.779e-158	507.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,1XTX4@135623|Vibrionales	135623|Vibrionales	E	COG1448 Aspartate tyrosine aromatic aminotransferase	aspC	-	2.6.1.57	ko:K00832	ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	M00024,M00025,M00034,M00040	R00694,R00734,R01731,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WH3_k127_11692572_0	452637.Oter_0123	2.064e-80	278.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	safC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
WH3_k127_11748536_0	1267535.KB906767_gene4370	1.645e-150	483.0	COG0399@1|root,COG0399@2|Bacteria,3Y3PT@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.98	ko:K13017	ko00520,map00520	-	R10141	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
WH3_k127_11760799_1	204669.Acid345_3790	1.19e-46	178.0	COG0279@1|root,COG0279@2|Bacteria,3Y4UX@57723|Acidobacteria,2JJJ4@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
WH3_k127_11760799_0	237368.SCABRO_01298	1.374e-123	409.0	COG0513@1|root,COG0513@2|Bacteria,2IX02@203682|Planctomycetes	2|Bacteria	JKL	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	dedA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
WH3_k127_11760799_2	1121904.ARBP01000002_gene7183	1.469e-25	107.0	COG3291@1|root,COG3291@2|Bacteria,4PMYH@976|Bacteroidetes,47YKQ@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
WH3_k127_11781063_0	338966.Ppro_1833	2.089e-56	204.0	COG0476@1|root,COG0476@2|Bacteria,1R87S@1224|Proteobacteria,42R16@68525|delta/epsilon subdivisions,2WNUM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	ThiF family	-	-	2.7.7.73	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
WH3_k127_11781063_2	983920.Y88_2834	7.791e-10	61.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2TSXS@28211|Alphaproteobacteria,2K0MM@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
WH3_k127_11781063_1	338963.Pcar_0609	1.013e-31	125.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,43S5G@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
WH3_k127_11792339_0	768486.EHR_00475	8.945e-75	264.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,4B0Y1@81852|Enterococcaceae	91061|Bacilli	E	Belongs to the peptidase M24B family	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
WH3_k127_11796849_0	1142394.PSMK_25540	3.078e-41	160.0	COG0220@1|root,COG0220@2|Bacteria,2IZJM@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
WH3_k127_11796849_2	441769.ABFU01000012_gene2676	4.773e-05	53.0	COG1335@1|root,COG1335@2|Bacteria,1VEGS@1239|Firmicutes,4HR3B@91061|Bacilli,1ZHUU@1386|Bacillus	91061|Bacilli	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
WH3_k127_11796849_1	1120953.AUBH01000004_gene3016	8.651e-07	59.0	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,1RGWM@1224|Proteobacteria,1SKIX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	UW	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_3
WH3_k127_11806534_0	344747.PM8797T_32180	1.589e-268	842.0	COG0556@1|root,COG0556@2|Bacteria,2IWS1@203682|Planctomycetes	203682|Planctomycetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WH3_k127_11816889_1	742738.HMPREF9460_02003	1.35e-14	84.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,268U9@186813|unclassified Clostridiales	186801|Clostridia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
WH3_k127_11816889_0	237368.SCABRO_00310	1.586e-54	209.0	COG2027@1|root,COG2027@2|Bacteria,2IYAC@203682|Planctomycetes	203682|Planctomycetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
WH3_k127_1188462_0	1279015.KB908454_gene727	1.442e-28	125.0	COG1462@1|root,COG1462@2|Bacteria,1RH5B@1224|Proteobacteria,1SAKG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	curli production assembly transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
WH3_k127_1189553_0	62928.azo1560	8.746e-07	52.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria,2KV34@206389|Rhodocyclales	206389|Rhodocyclales	KL	helicase	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2
WH3_k127_11914017_1	945713.IALB_2664	1.436e-31	130.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
WH3_k127_11914017_0	694431.DESACE_00450	3.648e-240	759.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42N5M@68525|delta/epsilon subdivisions,2WIIV@28221|Deltaproteobacteria,2M6MV@213113|Desulfurellales	28221|Deltaproteobacteria	C	Aconitase family (aconitate hydratase)	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2763	Aconitase,Aconitase_C
WH3_k127_11918651_2	1307761.L21SP2_0496	3.978e-26	113.0	COG0546@1|root,COG0546@2|Bacteria,2J5KH@203691|Spirochaetes	203691|Spirochaetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
WH3_k127_11918651_1	403833.Pmob_0444	2.873e-92	310.0	COG1028@1|root,COG1028@2|Bacteria,2GDVT@200918|Thermotogae	200918|Thermotogae	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH3_k127_11918651_0	1499967.BAYZ01000074_gene2175	7.795e-108	357.0	COG4277@1|root,COG4277@2|Bacteria	2|Bacteria	-	-	MA20_15955	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	HHH_3,Radical_SAM
WH3_k127_11922845_0	177437.HRM2_43980	5.675e-82	292.0	COG0840@1|root,COG0840@2|Bacteria,1N12X@1224|Proteobacteria,42UQY@68525|delta/epsilon subdivisions,2WPZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	transmembrane signaling receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11929893_0	521674.Plim_1789	1.507e-98	343.0	COG0768@1|root,COG0768@2|Bacteria,2IXEK@203682|Planctomycetes	203682|Planctomycetes	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
WH3_k127_11929893_2	1033737.CAEV01000007_gene2584	2.611e-08	65.0	COG1652@1|root,COG1652@2|Bacteria,1V4J4@1239|Firmicutes,25DK3@186801|Clostridia	186801|Clostridia	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
WH3_k127_11929893_3	522373.Smlt4276	0.0003044	52.0	COG1652@1|root,COG1652@2|Bacteria,1RD8K@1224|Proteobacteria,1SGZZ@1236|Gammaproteobacteria,1XC0C@135614|Xanthomonadales	135614|Xanthomonadales	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
WH3_k127_11929893_1	1158345.JNLL01000001_gene557	1.905e-14	74.0	COG0275@1|root,COG0275@2|Bacteria,2G3T6@200783|Aquificae	200783|Aquificae	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
WH3_k127_11930000_0	385682.AFSL01000072_gene1345	9.113e-73	249.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4N@976|Bacteroidetes,2G2S8@200643|Bacteroidia	976|Bacteroidetes	C	K00162 pyruvate dehydrogenase E1 component subunit beta	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
WH3_k127_11930000_1	189425.PGRAT_17905	1.622e-39	157.0	COG1349@1|root,COG1349@2|Bacteria,1UZ6T@1239|Firmicutes,4HBKU@91061|Bacilli,276FG@186822|Paenibacillaceae	91061|Bacilli	K	DeoR faimly transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
WH3_k127_11951278_0	177439.DP2712	2.709e-55	207.0	COG4487@1|root,COG4487@2|Bacteria	2|Bacteria	I	mechanosensitive ion channel activity	-	-	-	ko:K22051	-	-	-	-	ko00000,ko02000	1.A.23.1.2,1.A.23.1.3	-	-	DUF3086,MS_channel,MscS_TM,MscS_porin,PhageMin_Tail
WH3_k127_11954102_1	237368.SCABRO_02098	8.119e-41	152.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2IX0T@203682|Planctomycetes	203682|Planctomycetes	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PEP-utilizers,PPDK_N
WH3_k127_11954102_0	242619.PG_1753	9.332e-105	348.0	COG0709@1|root,COG0709@2|Bacteria,4NI4R@976|Bacteroidetes,2FRGC@200643|Bacteroidia	976|Bacteroidetes	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
WH3_k127_11962983_0	1408473.JHXO01000006_gene1341	0.0	1039.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
WH3_k127_11962983_2	595460.RRSWK_01690	4.361e-23	104.0	COG0799@1|root,COG0799@2|Bacteria,2J0AM@203682|Planctomycetes	203682|Planctomycetes	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
WH3_k127_11962983_1	349521.HCH_01116	3.632e-59	211.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1XHDI@135619|Oceanospirillales	135619|Oceanospirillales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
WH3_k127_11973874_1	927658.AJUM01000022_gene1289	3.588e-18	93.0	COG1102@1|root,COG1102@2|Bacteria,4NU66@976|Bacteroidetes,2G20S@200643|Bacteroidia,3XJCI@558415|Marinilabiliaceae	976|Bacteroidetes	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
WH3_k127_11973874_0	243231.GSU2429	1.479e-44	179.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria,43SP4@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	SurA N-terminal domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
WH3_k127_11984142_0	402881.Plav_3501	1.087e-121	398.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2TSRD@28211|Alphaproteobacteria,1JN9Q@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
WH3_k127_11984142_1	99598.Cal7507_0947	1.579e-40	153.0	2DNS7@1|root,32YWC@2|Bacteria,1G8QD@1117|Cyanobacteria,1HP4W@1161|Nostocales	1117|Cyanobacteria	J	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WH3_k127_11991046_0	886293.Sinac_5359	3.84e-113	374.0	COG1158@1|root,COG1158@2|Bacteria,2IXV3@203682|Planctomycetes	203682|Planctomycetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
WH3_k127_11997693_0	344747.PM8797T_16857	9.662e-166	535.0	COG3119@1|root,COG3119@2|Bacteria,2IXP1@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
WH3_k127_11997693_1	247490.KSU1_D1037	1.989e-97	323.0	COG1186@1|root,COG1186@2|Bacteria,2IWU3@203682|Planctomycetes	203682|Planctomycetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WH3_k127_12006896_0	1226325.HMPREF1548_05284	6.468e-59	221.0	COG3119@1|root,COG3119@2|Bacteria,1TQEP@1239|Firmicutes,2482B@186801|Clostridia	186801|Clostridia	P	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
WH3_k127_120117_1	326427.Cagg_3085	8.239e-39	155.0	COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi,375PN@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WH3_k127_120117_0	1095769.CAHF01000005_gene1469	2.849e-77	264.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,2VKWB@28216|Betaproteobacteria	28216|Betaproteobacteria	J	elongation factor G	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
WH3_k127_12017147_3	1121428.DESHY_110164___1	4.614e-17	84.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia,2630S@186807|Peptococcaceae	186801|Clostridia	T	Belongs to the UPF0237 family	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
WH3_k127_12017147_0	644282.Deba_1938	9.419e-172	550.0	COG2848@1|root,COG2848@2|Bacteria,1NAFG@1224|Proteobacteria,42NH7@68525|delta/epsilon subdivisions,2WJJM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
WH3_k127_12017147_1	698769.JFBD01000045_gene706	1.154e-144	469.0	COG1301@1|root,COG1301@2|Bacteria,1TQ3F@1239|Firmicutes,4HBZM@91061|Bacilli,4C5ER@84406|Virgibacillus	91061|Bacilli	U	Sodium:dicarboxylate symporter family	gltT	-	-	-	-	-	-	-	-	-	-	-	SDF
WH3_k127_12017147_2	207559.Dde_0965	7.017e-98	329.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
WH3_k127_12020183_0	1267534.KB906754_gene3315	4.96e-72	245.0	COG3408@1|root,COG3408@2|Bacteria,3Y47W@57723|Acidobacteria,2JKGP@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
WH3_k127_12020183_1	768671.ThimaDRAFT_2103	1.059e-25	115.0	2EBP0@1|root,335P6@2|Bacteria,1N33Y@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12020183_2	1304885.AUEY01000087_gene92	3.46e-10	69.0	28PW7@1|root,32EDN@2|Bacteria,1N0AP@1224|Proteobacteria,42UF5@68525|delta/epsilon subdivisions,2WQ2P@28221|Deltaproteobacteria,2MKES@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3313
WH3_k127_12020183_3	666509.RCA23_c10910	6.116e-08	60.0	COG0457@1|root,COG4122@1|root,COG0457@2|Bacteria,COG4122@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_1,TPR_11,TPR_12,TPR_16,TPR_2,TPR_6,TPR_8
WH3_k127_12043920_0	886377.Murru_3357	4.494e-13	82.0	COG1319@1|root,COG2304@1|root,COG3209@1|root,COG4935@1|root,COG1319@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,COG4935@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF5011,HYR,SprB
WH3_k127_1205136_2	421531.IX38_16080	8.407e-43	160.0	COG1943@1|root,COG1943@2|Bacteria,4NNQJ@976|Bacteroidetes,1I8RN@117743|Flavobacteriia,3ZRXE@59732|Chryseobacterium	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WH3_k127_1205136_1	1142394.PSMK_29720	3.432e-43	164.0	COG0461@1|root,COG0461@2|Bacteria,2IZA7@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
WH3_k127_1205136_3	1033810.HLPCO_000587	7.044e-30	120.0	arCOG15062@1|root,32Y8D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PQ-loop
WH3_k127_1205136_0	1033810.HLPCO_000061	5.146e-135	451.0	COG1132@1|root,COG1132@2|Bacteria,2NQH2@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WH3_k127_12071339_2	641491.DND132_1939	2.682e-66	243.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42PU9@68525|delta/epsilon subdivisions,2WU8U@28221|Deltaproteobacteria,2M8K7@213115|Desulfovibrionales	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WH3_k127_12071339_1	595460.RRSWK_02559	3.2e-126	422.0	COG0845@1|root,COG0845@2|Bacteria,2IZ22@203682|Planctomycetes	203682|Planctomycetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23
WH3_k127_12071339_4	335543.Sfum_1432	3.069e-13	83.0	COG3350@1|root,COG3350@2|Bacteria,1NE2T@1224|Proteobacteria,42VZQ@68525|delta/epsilon subdivisions,2WSDU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
WH3_k127_12071339_3	335543.Sfum_1432	1.879e-13	75.0	COG3350@1|root,COG3350@2|Bacteria,1NE2T@1224|Proteobacteria,42VZQ@68525|delta/epsilon subdivisions,2WSDU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
WH3_k127_12071339_0	1121459.AQXE01000014_gene351	7.902e-266	835.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2M9PX@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
WH3_k127_120803_0	1123508.JH636444_gene5211	2.242e-51	191.0	COG0496@1|root,COG0496@2|Bacteria,2IXPI@203682|Planctomycetes	203682|Planctomycetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
WH3_k127_120803_1	237368.SCABRO_03235	2.042e-47	179.0	COG0062@1|root,COG0062@2|Bacteria,2IZU6@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX	nnrE	-	5.1.99.6	ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	YjeF_N
WH3_k127_12086711_2	1210884.HG799464_gene11206	2.69e-26	113.0	COG3335@1|root,COG3335@2|Bacteria,2J1BU@203682|Planctomycetes	203682|Planctomycetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
WH3_k127_12086711_1	416348.Hlac_3636	2.242e-32	131.0	COG3415@1|root,arCOG02128@2157|Archaea	2157|Archaea	L	COG3415 Transposase and inactivated derivatives	-	-	-	ko:K07499	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32,HTH_33
WH3_k127_12086711_3	1123242.JH636434_gene3607	3.066e-25	111.0	COG3293@1|root,COG3293@2|Bacteria,2IZ9E@203682|Planctomycetes	203682|Planctomycetes	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
WH3_k127_12086711_0	690850.Desaf_3258	6.734e-57	201.0	COG3293@1|root,COG3293@2|Bacteria,1R5NV@1224|Proteobacteria,430FR@68525|delta/epsilon subdivisions,2WVKI@28221|Deltaproteobacteria,2MFEK@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF4096
WH3_k127_12086711_4	1246626.BleG1_1909	1.76e-20	93.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus	91061|Bacilli	C	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
WH3_k127_12090459_0	443143.GM18_0255	6.034e-308	974.0	COG2885@1|root,COG3203@1|root,COG4719@1|root,COG2885@2|Bacteria,COG3203@2|Bacteria,COG4719@2|Bacteria,1QW22@1224|Proteobacteria,42NCQ@68525|delta/epsilon subdivisions,2WMJP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA
WH3_k127_12103652_6	926692.AZYG01000064_gene969	0.0004367	49.0	COG3167@1|root,COG3167@2|Bacteria	2|Bacteria	NU	carbon utilization	-	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
WH3_k127_12103652_0	1142394.PSMK_14360	2.099e-81	293.0	COG4796@1|root,COG4796@2|Bacteria,2IY1C@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the GSP D family	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	STN,Secretin
WH3_k127_12103652_4	368407.Memar_0060	1.331e-10	73.0	arCOG03042@1|root,arCOG03042@2157|Archaea,2Y7NV@28890|Euryarchaeota,2NAUB@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
WH3_k127_12103652_1	314230.DSM3645_24040	2.049e-65	241.0	COG5002@1|root,COG5002@2|Bacteria,2IZ3S@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WH3_k127_12103652_3	530564.Psta_3636	1.001e-25	111.0	COG0745@1|root,COG0745@2|Bacteria,2J15S@203682|Planctomycetes	203682|Planctomycetes	T	PFAM response regulator receiver	-	-	-	ko:K11329	ko02020,map02020	M00467	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WH3_k127_12103652_2	344747.PM8797T_31865	2.669e-64	241.0	COG2206@1|root,COG2206@2|Bacteria,2IWTK@203682|Planctomycetes	203682|Planctomycetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_2,HD
WH3_k127_12103652_5	1379698.RBG1_1C00001G0631	2.139e-07	57.0	COG1366@1|root,COG1366@2|Bacteria,2NRCS@2323|unclassified Bacteria	2|Bacteria	T	STAS domain	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
WH3_k127_12134090_2	71139.XP_010029868.1	6.599e-18	90.0	COG1385@1|root,2QPPV@2759|Eukaryota,37PHM@33090|Viridiplantae,3G8B1@35493|Streptophyta	35493|Streptophyta	J	Ribosomal RNA small subunit methyltransferase	-	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
WH3_k127_12134090_1	716544.wcw_1068	5.688e-60	211.0	COG0652@1|root,COG0652@2|Bacteria,2JG2B@204428|Chlamydiae	204428|Chlamydiae	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
WH3_k127_12134090_0	313628.LNTAR_02467	2.677e-75	268.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WH3_k127_12141539_1	1379698.RBG1_1C00001G0979	9.742e-44	164.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
WH3_k127_12141539_0	269799.Gmet_2052	3.941e-74	260.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,43U4M@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WH3_k127_12205173_3	443143.GM18_2397	1.703e-21	98.0	COG0640@1|root,COG0640@2|Bacteria,1RGYC@1224|Proteobacteria,42X86@68525|delta/epsilon subdivisions,2WSJA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
WH3_k127_12205173_0	596152.DesU5LDRAFT_3926	1.385e-145	468.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42MF8@68525|delta/epsilon subdivisions,2WJFH@28221|Deltaproteobacteria,2M8CG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
WH3_k127_12205173_1	1304885.AUEY01000001_gene3202	6.971e-67	230.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42RQI@68525|delta/epsilon subdivisions,2WNEC@28221|Deltaproteobacteria,2MJU4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
WH3_k127_12205173_2	1295642.H839_08853	8.713e-36	138.0	COG0500@1|root,COG2226@2|Bacteria,1U5XV@1239|Firmicutes,4HBHC@91061|Bacilli,1WEXC@129337|Geobacillus	91061|Bacilli	Q	Hypothetical methyltransferase	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
WH3_k127_12211332_0	1142394.PSMK_17290	1.333e-84	289.0	COG0416@1|root,COG0416@2|Bacteria,2IWUY@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
WH3_k127_12211332_1	273068.TTE1475	1.908e-19	89.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,42ER1@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WH3_k127_12214169_0	765911.Thivi_0092	7.21e-80	271.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,1WXBT@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
WH3_k127_12216679_1	1346.DQ08_08000	6.007e-10	72.0	COG3250@1|root,COG3250@2|Bacteria,1TPK7@1239|Firmicutes,4HBHM@91061|Bacilli	91061|Bacilli	G	Belongs to the glycosyl hydrolase 2 family	bgaA	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Big_4,DUF4982,G5,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Gram_pos_anchor,YSIRK_signal
WH3_k127_12216679_0	319224.Sputcn32_2047	2.411e-16	93.0	COG3507@1|root,COG3507@2|Bacteria,1R4H2@1224|Proteobacteria,1RSCC@1236|Gammaproteobacteria,2QAFW@267890|Shewanellaceae	1236|Gammaproteobacteria	G	C-terminal of Glycosyl hydrolases family 43	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	GH43_C,Glyco_hydro_43,Laminin_G_3
WH3_k127_12227667_1	1122138.AQUZ01000016_gene162	0.0001088	51.0	COG1011@1|root,COG1011@2|Bacteria,2HZ7F@201174|Actinobacteria,4DQFA@85009|Propionibacteriales	201174|Actinobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase_like
WH3_k127_12227667_0	880072.Desac_0563	1.005e-127	416.0	COG0119@1|root,COG0119@2|Bacteria,1R8DM@1224|Proteobacteria,42PDN@68525|delta/epsilon subdivisions,2WKIJ@28221|Deltaproteobacteria,2MQ4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Pyruvate carboxyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like,dCache_1
WH3_k127_12228358_1	177437.HRM2_23770	1.633e-57	205.0	COG4656@1|root,COG4656@2|Bacteria,1PJE1@1224|Proteobacteria,42P69@68525|delta/epsilon subdivisions,2WIM9@28221|Deltaproteobacteria,2MI2H@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB
WH3_k127_12228358_0	292459.STH897	2.714e-75	264.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
WH3_k127_12228358_3	350688.Clos_1773	0.0007191	49.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia,36K2X@31979|Clostridiaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
WH3_k127_12228358_2	1121405.dsmv_3374	5.866e-23	102.0	COG4660@1|root,COG4660@2|Bacteria,1R4EB@1224|Proteobacteria,42PW0@68525|delta/epsilon subdivisions,2WKTN@28221|Deltaproteobacteria,2MJEI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the NqrDE RnfAE family	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
WH3_k127_12236330_1	1123508.JH636443_gene4517	2.402e-34	133.0	COG0234@1|root,COG0234@2|Bacteria,2J027@203682|Planctomycetes	203682|Planctomycetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
WH3_k127_12236330_2	575540.Isop_2837	1.444e-23	101.0	COG0459@1|root,COG0459@2|Bacteria,2IXA7@203682|Planctomycetes	203682|Planctomycetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WH3_k127_12236330_0	247490.KSU1_C0394	6.774e-35	135.0	COG0459@1|root,COG0459@2|Bacteria,2IXA7@203682|Planctomycetes	203682|Planctomycetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WH3_k127_1224063_0	1142394.PSMK_14530	2.195e-161	514.0	COG1077@1|root,COG1077@2|Bacteria,2IXSJ@203682|Planctomycetes	203682|Planctomycetes	D	COG1077 Actin-like ATPase involved in cell morphogenesis	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
WH3_k127_1224063_2	1177181.T9A_02085	6.541e-09	66.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,1XHGW@135619|Oceanospirillales	135619|Oceanospirillales	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
WH3_k127_1224063_1	317025.Tcr_1633	1.326e-25	120.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,45ZU0@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
WH3_k127_12252358_2	29486.NJ56_02725	5.776e-71	241.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,1RMZB@1236|Gammaproteobacteria,41D7U@629|Yersinia	1236|Gammaproteobacteria	IQ	2-deoxy-D-gluconate 3-dehydrogenase	kduD	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
WH3_k127_12252358_0	1187851.A33M_2009	3.713e-160	516.0	COG0524@1|root,COG0524@2|Bacteria,1QNWF@1224|Proteobacteria,2TTP6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
WH3_k127_12252358_1	509190.Cseg_1555	3.991e-78	267.0	COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,2TUMH@28211|Alphaproteobacteria,2KGGR@204458|Caulobacterales	204458|Caulobacterales	G	Aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
WH3_k127_12252358_3	344747.PM8797T_05260	1.588e-44	169.0	COG0344@1|root,COG0344@2|Bacteria,2J0DJ@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	DUF4149,G3P_acyltransf
WH3_k127_12252358_4	575540.Isop_0825	1.001e-36	154.0	COG0438@1|root,COG0438@2|Bacteria,2IZ1G@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
WH3_k127_12252358_5	313628.LNTAR_01807	5.323e-06	51.0	COG0515@1|root,COG0515@2|Bacteria	313628.LNTAR_01807|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12260531_0	1134912.AJTV01000023_gene2878	1.373e-169	551.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TSN8@28211|Alphaproteobacteria,36Y6U@31993|Methylocystaceae	28211|Alphaproteobacteria	MU	Outer membrane efflux protein	oprN	-	-	ko:K18300,ko:K19593	-	M00641,M00769	-	-	ko00000,ko00002,ko01504,ko02000	1.B.17,2.A.6.2.34	-	-	OEP
WH3_k127_12260531_1	1123242.JH636435_gene1842	4.255e-74	264.0	COG0617@1|root,COG0617@2|Bacteria,2IXYM@203682|Planctomycetes	203682|Planctomycetes	H	tRNA nucleotidyltransferase poly(A) polymerase	papS	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
WH3_k127_12289863_1	530564.Psta_3847	9.256e-59	216.0	COG0618@1|root,COG0618@2|Bacteria,2IYQ0@203682|Planctomycetes	203682|Planctomycetes	S	phosphoesterase RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WH3_k127_12289863_0	1210884.HG799464_gene10878	3.851e-103	343.0	COG0253@1|root,COG0253@2|Bacteria,2IYCH@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
WH3_k127_12289863_2	237368.SCABRO_00775	9.556e-23	104.0	COG1039@1|root,COG1039@2|Bacteria,2IZ83@203682|Planctomycetes	203682|Planctomycetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12305537_0	1411685.U062_01308	1.324e-81	284.0	COG3264@1|root,COG3264@2|Bacteria,1QUBW@1224|Proteobacteria,1T1SF@1236|Gammaproteobacteria,1J5SF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0668 Small-conductance mechanosensitive channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
WH3_k127_12305537_1	583355.Caka_1113	1.579e-11	68.0	2ERTX@1|root,33JD4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12308379_0	1121904.ARBP01000027_gene731	2.967e-79	281.0	COG5434@1|root,COG5434@2|Bacteria,4NID5@976|Bacteroidetes,47S55@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28
WH3_k127_12308379_1	477974.Daud_2231	1.288e-38	150.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,261UV@186807|Peptococcaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
WH3_k127_12313294_0	311424.DhcVS_940	4.039e-127	421.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G8XD@200795|Chloroflexi,34CY9@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
WH3_k127_12319854_0	314230.DSM3645_17695	9.119e-143	458.0	COG0473@1|root,COG0473@2|Bacteria,2IXBE@203682|Planctomycetes	203682|Planctomycetes	C	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WH3_k127_12319854_2	314230.DSM3645_17705	5.366e-73	259.0	COG1663@1|root,COG1663@2|Bacteria,2IXYX@203682|Planctomycetes	203682|Planctomycetes	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
WH3_k127_12319854_1	1210884.HG799465_gene11565	1.107e-134	445.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,2IY6V@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
WH3_k127_12319854_4	395961.Cyan7425_3729	2.229e-46	181.0	COG0241@1|root,COG0241@2|Bacteria,1G1I4@1117|Cyanobacteria,3KFY1@43988|Cyanothece	1117|Cyanobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_like
WH3_k127_12319854_3	575540.Isop_1281	1.762e-61	224.0	COG0859@1|root,COG0859@2|Bacteria,2IXD5@203682|Planctomycetes	203682|Planctomycetes	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WH3_k127_12328161_0	1415780.JPOG01000001_gene541	1.475e-20	94.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1X46K@135614|Xanthomonadales	135614|Xanthomonadales	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
WH3_k127_12330325_0	880073.Calab_1142	1.46e-150	480.0	COG1350@1|root,COG1350@2|Bacteria,2NNY3@2323|unclassified Bacteria	2|Bacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WH3_k127_12330325_1	158189.SpiBuddy_0912	5.69e-21	94.0	COG2973@1|root,COG2973@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	trpR	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006355,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009072,GO:0009308,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0034641,GO:0042430,GO:0043436,GO:0043565,GO:0044106,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901360,GO:1901363,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141	-	ko:K03720	-	-	-	-	ko00000,ko03000	-	-	-	Trp_repressor
WH3_k127_12361819_0	401526.TcarDRAFT_1764	8.072e-68	241.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H2C6@909932|Negativicutes	909932|Negativicutes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
WH3_k127_12361819_1	1142394.PSMK_20550	1.762e-15	81.0	2CBRY@1|root,33DAH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12366135_0	521674.Plim_3831	2.702e-157	505.0	COG0015@1|root,COG0015@2|Bacteria,2IXU4@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
WH3_k127_12385646_0	401053.AciPR4_2893	1.694e-73	263.0	COG3547@1|root,COG3547@2|Bacteria,3Y5SI@57723|Acidobacteria,2JKWK@204432|Acidobacteriia	204432|Acidobacteriia	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
WH3_k127_12389448_3	344747.PM8797T_15181	5.898e-23	101.0	COG2331@1|root,COG2331@2|Bacteria,2J0TW@203682|Planctomycetes	203682|Planctomycetes	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WH3_k127_12389448_2	1196324.A374_10815	6.601e-24	109.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
WH3_k127_12389448_0	595460.RRSWK_03593	1.889e-113	377.0	COG0484@1|root,COG0484@2|Bacteria,2IXQJ@203682|Planctomycetes	203682|Planctomycetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WH3_k127_12389448_1	237368.SCABRO_03915	2.943e-38	145.0	COG0459@1|root,COG0459@2|Bacteria,2IXJW@203682|Planctomycetes	203682|Planctomycetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WH3_k127_12413917_1	521674.Plim_4057	4.508e-58	205.0	COG0249@1|root,COG0249@2|Bacteria,2IXGV@203682|Planctomycetes	203682|Planctomycetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WH3_k127_12413917_0	886293.Sinac_6584	4.202e-82	286.0	COG0249@1|root,COG0249@2|Bacteria,2IXGV@203682|Planctomycetes	203682|Planctomycetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WH3_k127_12422966_1	177437.HRM2_48620	5.199e-80	281.0	COG2230@1|root,COG3496@1|root,COG2230@2|Bacteria,COG3496@2|Bacteria,1MX3U@1224|Proteobacteria,42PB7@68525|delta/epsilon subdivisions,2WKGA@28221|Deltaproteobacteria,2MI5S@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS,DUF1365
WH3_k127_12422966_0	1121918.ARWE01000001_gene186	1.942e-112	379.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,42N4S@68525|delta/epsilon subdivisions,2WJXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
WH3_k127_12422966_2	1123376.AUIU01000014_gene633	2.443e-36	156.0	COG1906@1|root,COG1906@2|Bacteria	2|Bacteria	C	membrane	-	-	-	ko:K09133	-	-	-	-	ko00000	-	-	-	DUF401
WH3_k127_12445545_1	338963.Pcar_0143	4.674e-36	144.0	29X52@1|root,30IU1@2|Bacteria,1N8YP@1224|Proteobacteria,42WWU@68525|delta/epsilon subdivisions,2WT2G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12445545_0	439235.Dalk_5076	1.562e-138	447.0	COG2268@1|root,COG2268@2|Bacteria,1P50K@1224|Proteobacteria,42PJG@68525|delta/epsilon subdivisions,2WQ9J@28221|Deltaproteobacteria,2MMDR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Flotillin	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
WH3_k127_12447197_1	886293.Sinac_2883	3.327e-88	297.0	COG1762@1|root,COG3311@1|root,COG1762@2|Bacteria,COG3311@2|Bacteria,2IZFY@203682|Planctomycetes	203682|Planctomycetes	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	HTH_17,PTS_EIIA_2
WH3_k127_12447197_0	1232410.KI421427_gene1299	3.595e-184	597.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,42NFV@68525|delta/epsilon subdivisions,2WJZ0@28221|Deltaproteobacteria,43T2H@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	ehrA-2	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
WH3_k127_12447197_2	1232410.KI421427_gene1299	1.527e-52	192.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,42NFV@68525|delta/epsilon subdivisions,2WJZ0@28221|Deltaproteobacteria,43T2H@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	ehrA-2	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
WH3_k127_12453338_0	575540.Isop_2452	1.76e-86	297.0	COG5525@1|root,COG5525@2|Bacteria,2IXN3@203682|Planctomycetes	203682|Planctomycetes	S	Phage terminase large subunit (GpA)	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_GpA
WH3_k127_1248806_1	1303518.CCALI_01797	2.991e-06	58.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10,T2SSG
WH3_k127_1248806_0	1499967.BAYZ01000074_gene2175	1.093e-53	192.0	COG4277@1|root,COG4277@2|Bacteria	2|Bacteria	-	-	MA20_15955	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	HHH_3,Radical_SAM
WH3_k127_12499353_1	886293.Sinac_0499	1.215e-286	887.0	COG0086@1|root,COG0086@2|Bacteria,2IXGN@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
WH3_k127_12499353_0	1142394.PSMK_24450	8.118e-309	961.0	COG0085@1|root,COG0085@2|Bacteria,2IXVZ@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
WH3_k127_12517746_0	247490.KSU1_C0572	1.477e-49	186.0	COG0115@1|root,COG0115@2|Bacteria,2J20K@203682|Planctomycetes	203682|Planctomycetes	EH	Amino-transferase class IV	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_4
WH3_k127_12517746_1	1056816.JAFQ01000004_gene679	8.327e-08	61.0	COG0673@1|root,COG0673@2|Bacteria,2GM7J@201174|Actinobacteria,4G00X@85025|Nocardiaceae	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WH3_k127_12531257_0	1142394.PSMK_23630	3.328e-66	236.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2IYCQ@203682|Planctomycetes	203682|Planctomycetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
WH3_k127_12532362_1	411464.DESPIG_01886	6.951e-09	56.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,42MHS@68525|delta/epsilon subdivisions,2WJQW@28221|Deltaproteobacteria,2M9G7@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Saccharopine dehydrogenase	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0902	Sacchrp_dh_C,Sacchrp_dh_NADP
WH3_k127_12532362_0	373994.Riv7116_3749	2.373e-112	372.0	COG1397@1|root,COG1397@2|Bacteria,1G30S@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
WH3_k127_12538424_0	865937.Gilli_0923	4.865e-31	125.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,1HZJW@117743|Flavobacteriia,2P7D8@244698|Gillisia	976|Bacteroidetes	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
WH3_k127_12538424_1	314230.DSM3645_08472	1.845e-19	90.0	COG1551@1|root,COG1551@2|Bacteria,2J0YE@203682|Planctomycetes	203682|Planctomycetes	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
WH3_k127_12538424_2	1151292.QEW_1361	1.156e-08	60.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
WH3_k127_12539154_1	344747.PM8797T_03439	4.472e-84	284.0	COG1418@1|root,COG1418@2|Bacteria,2IX35@203682|Planctomycetes	203682|Planctomycetes	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
WH3_k127_12539154_0	247490.KSU1_D0799	3.7e-87	296.0	COG1692@1|root,COG1692@2|Bacteria,2IXR1@203682|Planctomycetes	203682|Planctomycetes	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
WH3_k127_12558179_1	338963.Pcar_2325	1.519e-45	169.0	COG1246@1|root,COG1246@2|Bacteria,1RHT7@1224|Proteobacteria,42SGE@68525|delta/epsilon subdivisions,2WP91@28221|Deltaproteobacteria,43SH6@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Acetyltransferase (GNAT) domain	argA	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0946	Acetyltransf_1,Acetyltransf_7
WH3_k127_12558179_0	314230.DSM3645_28652	1.086e-99	342.0	COG1508@1|root,COG1508@2|Bacteria,2IXGU@203682|Planctomycetes	203682|Planctomycetes	K	rna polymerase sigma-54 factor	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
WH3_k127_12567220_0	1259795.ARJK01000004_gene1353	3.953e-111	371.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,42EQX@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM 2-nitropropane dioxygenase NPD	-	-	-	-	-	-	-	-	-	-	-	-	NMO
WH3_k127_12567220_1	497964.CfE428DRAFT_2195	2.912e-06	58.0	COG3271@1|root,COG3271@2|Bacteria,46VSC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase C39 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39
WH3_k127_12580520_0	497964.CfE428DRAFT_4943	1.607e-150	517.0	COG0577@1|root,COG0577@2|Bacteria,46U6N@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
WH3_k127_12580520_3	497964.CfE428DRAFT_4944	6.222e-62	223.0	COG1136@1|root,COG1136@2|Bacteria,46V6W@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WH3_k127_12580520_2	1168034.FH5T_01525	3.008e-89	311.0	COG0438@1|root,COG0438@2|Bacteria,4P10Z@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
WH3_k127_12580520_1	1288079.AUKN01000003_gene3439	1.248e-109	372.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the pyruvate kinase family	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
WH3_k127_12590031_0	697282.Mettu_0954	3.043e-17	86.0	COG0740@1|root,COG3740@1|root,COG0740@2|Bacteria,COG3740@2|Bacteria,1MUQ9@1224|Proteobacteria,1RRQA@1236|Gammaproteobacteria,1XGBE@135618|Methylococcales	135618|Methylococcales	OU	Belongs to the peptidase S14 family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_1261889_0	66692.ABC2871	2.51e-160	513.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,1ZARG@1386|Bacillus	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
WH3_k127_1261889_2	1123023.JIAI01000001_gene7571	9.361e-13	75.0	COG1437@1|root,COG1437@2|Bacteria,2IM8H@201174|Actinobacteria,4EB06@85010|Pseudonocardiales	201174|Actinobacteria	F	CYTH	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
WH3_k127_1261889_1	344747.PM8797T_10589	4.063e-34	143.0	COG1597@1|root,COG1597@2|Bacteria,2IZX6@203682|Planctomycetes	203682|Planctomycetes	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
WH3_k127_12630599_0	868595.Desca_1979	5.01e-81	276.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,264NP@186807|Peptococcaceae	186801|Clostridia	L	PFAM Endonuclease Exonuclease phosphatase	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
WH3_k127_12630599_1	1499967.BAYZ01000075_gene2071	2.513e-67	248.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS-HPr
WH3_k127_12654097_0	574087.Acear_1431	2.668e-44	170.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,3WAED@53433|Halanaerobiales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
WH3_k127_12654097_1	1210884.HG799464_gene11025	9.769e-22	101.0	COG1520@1|root,COG1520@2|Bacteria,2IYZY@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
WH3_k127_12664017_1	1121930.AQXG01000001_gene1629	2.88e-43	181.0	COG0358@1|root,COG0358@2|Bacteria	2|Bacteria	L	DNA primase activity	-	-	3.6.4.12	ko:K17680	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	AAA_25,D5_N,DUF3631,DUF3987,PriCT_1,Toprim_2
WH3_k127_12664017_0	1125863.JAFN01000001_gene2509	4.159e-125	428.0	COG4643@1|root,COG4643@2|Bacteria,1N08G@1224|Proteobacteria	1224|Proteobacteria	L	membrane spanning protein Brucella melitensis 16M gi 17987979 ref	-	-	-	-	-	-	-	-	-	-	-	-	DUF3987
WH3_k127_12682783_0	234267.Acid_2166	2.193e-96	330.0	COG1457@1|root,COG1457@2|Bacteria,3Y6MB@57723|Acidobacteria	57723|Acidobacteria	F	Belongs to the purine-cytosine permease (2.A.39) family	-	-	-	ko:K10974	-	-	-	-	ko00000,ko02000	2.A.39.1	-	-	Transp_cyt_pur
WH3_k127_12699924_1	1340493.JNIF01000004_gene1117	7.03e-33	136.0	COG3752@1|root,COG3752@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
WH3_k127_12699924_0	472759.Nhal_0313	8.455e-94	318.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1WX07@135613|Chromatiales	135613|Chromatiales	M	PFAM Cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
WH3_k127_12715425_1	1121346.KB899819_gene2509	3.626e-35	138.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli,26R5Q@186822|Paenibacillaceae	91061|Bacilli	P	Potassium uptake system protein	ktrA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
WH3_k127_12715425_0	880073.Calab_0113	5.987e-91	321.0	COG0168@1|root,COG0168@2|Bacteria,2NNW1@2323|unclassified Bacteria	2|Bacteria	P	Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
WH3_k127_12723095_1	880073.Calab_1440	6.172e-31	133.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	mpaA	GO:0000270,GO:0003674,GO:0003824,GO:0004040,GO:0004180,GO:0004181,GO:0005488,GO:0006022,GO:0006026,GO:0006027,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009050,GO:0009056,GO:0009057,GO:0009253,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019538,GO:0030203,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0046872,GO:0046914,GO:0061473,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K14054	-	-	-	-	ko00000	-	-	iEC55989_1330.EC55989_1490,iECO103_1326.ECO103_1491	Peptidase_M14
WH3_k127_12723095_0	243231.GSU1728	1.243e-101	338.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2WJ81@28221|Deltaproteobacteria,43T1P@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WH3_k127_12747845_0	1123508.JH636450_gene7092	0.0001971	53.0	COG3156@1|root,COG3156@2|Bacteria,2IXHV@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
WH3_k127_12769164_0	1142394.PSMK_29910	2.8e-90	305.0	COG0322@1|root,COG0322@2|Bacteria,2IWVR@203682|Planctomycetes	203682|Planctomycetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,UVR,UvrC_HhH_N
WH3_k127_12769164_1	292459.STH843	2.214e-45	184.0	COG2203@1|root,COG5002@1|root,COG5278@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
WH3_k127_12772620_0	1123073.KB899242_gene1468	1.706e-61	227.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,1RZBM@1236|Gammaproteobacteria,1X4YD@135614|Xanthomonadales	135614|Xanthomonadales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
WH3_k127_12780639_0	237368.SCABRO_00123	6.505e-88	301.0	COG3225@1|root,COG3225@2|Bacteria,2IXSG@203682|Planctomycetes	203682|Planctomycetes	N	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_5,ABC_transp_aux
WH3_k127_12807124_0	237368.SCABRO_03354	7.201e-78	276.0	COG0202@1|root,COG0457@1|root,COG0202@2|Bacteria,COG0457@2|Bacteria,2IXMK@203682|Planctomycetes	203682|Planctomycetes	K	rna polymerase alpha	-	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,TPR_1,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
WH3_k127_12807124_1	1304885.AUEY01000005_gene797	7.86e-21	102.0	COG2385@1|root,COG2385@2|Bacteria,1RGJS@1224|Proteobacteria,42RZE@68525|delta/epsilon subdivisions,2WNH8@28221|Deltaproteobacteria,2MN9B@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID,TPR_6,TPR_8
WH3_k127_12818056_0	517418.Ctha_1865	1.156e-85	308.0	COG5184@1|root,COG5492@1|root,COG5184@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,CHU_C,Calx-beta,ChW,Flg_new,Glug,Phage_TTP_12,RCC1
WH3_k127_12826186_0	1121012.AUKX01000074_gene31	9.607e-97	338.0	COG1554@1|root,COG1554@2|Bacteria,4NHVP@976|Bacteroidetes,1I8HC@117743|Flavobacteriia,23I16@178469|Arenibacter	976|Bacteroidetes	G	hydrolase, family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12869543_1	485918.Cpin_6512	4.477e-08	57.0	COG0501@1|root,COG0501@2|Bacteria,4NE0J@976|Bacteroidetes,1J0JU@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
WH3_k127_12869543_0	234267.Acid_3543	2.055e-09	68.0	COG1287@1|root,COG1287@2|Bacteria,3Y5FJ@57723|Acidobacteria	57723|Acidobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12881469_0	42256.RradSPS_2325	1.503e-116	386.0	COG1215@1|root,COG1215@2|Bacteria,2GJCE@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K11936,ko:K14666	ko02026,map02026	M00664	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
WH3_k127_12921559_0	762984.HMPREF9445_01895	4.599e-42	174.0	COG3250@1|root,COG3250@2|Bacteria,4NGNR@976|Bacteroidetes,2FQ2C@200643|Bacteroidia,4ANIJ@815|Bacteroidaceae	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C
WH3_k127_12933205_1	344747.PM8797T_08339	2.928e-30	123.0	COG1327@1|root,COG1327@2|Bacteria,2IZQ3@203682|Planctomycetes	203682|Planctomycetes	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
WH3_k127_12933205_2	247490.KSU1_C0073	8.154e-13	76.0	COG1328@1|root,COG1328@2|Bacteria	2|Bacteria	F	CTP reductase activity	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
WH3_k127_12933205_0	1121875.KB907549_gene1909	1.767e-37	143.0	COG4122@1|root,COG4122@2|Bacteria,4NJV1@976|Bacteroidetes,1HYRV@117743|Flavobacteriia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
WH3_k127_12953890_4	383372.Rcas_1791	1.083e-25	113.0	COG2606@1|root,COG2606@2|Bacteria,2G8TA@200795|Chloroflexi,377ER@32061|Chloroflexia	32061|Chloroflexia	S	PFAM YbaK prolyl-tRNA synthetase associated region	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
WH3_k127_12953890_0	756272.Plabr_1288	1.352e-58	213.0	COG1211@1|root,COG1211@2|Bacteria,2IYXJ@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
WH3_k127_12953890_2	255470.cbdbA1366	1.736e-42	165.0	COG3359@1|root,COG3359@2|Bacteria,2G6TK@200795|Chloroflexi,34CWC@301297|Dehalococcoidia	301297|Dehalococcoidia	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
WH3_k127_12953890_1	1499967.BAYZ01000088_gene5065	3.915e-51	189.0	COG2365@1|root,COG2365@2|Bacteria	2|Bacteria	T	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	DSPc,Y_phosphatase2,Y_phosphatase3
WH3_k127_12953890_3	1142394.PSMK_22320	8.583e-27	115.0	COG0240@1|root,COG0240@2|Bacteria,2IWWN@203682|Planctomycetes	203682|Planctomycetes	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
WH3_k127_12958558_0	639282.DEFDS_1109	2.853e-116	384.0	COG2804@1|root,COG2804@2|Bacteria,2GEP7@200930|Deferribacteres	200930|Deferribacteres	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
WH3_k127_12958558_1	1205908.AKXW01000023_gene866	4.132e-25	112.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1XTCY@135623|Vibrionales	135623|Vibrionales	U	general secretion pathway protein	epsF	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
WH3_k127_12991605_1	237368.SCABRO_03849	4.983e-63	227.0	COG0767@1|root,COG0767@2|Bacteria,2IX01@203682|Planctomycetes	203682|Planctomycetes	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
WH3_k127_12991605_0	1112274.KI911560_gene1179	5.919e-92	311.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,2KKIJ@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
WH3_k127_1302007_0	237368.SCABRO_00777	4.047e-77	266.0	COG0141@1|root,COG0141@2|Bacteria,2IXQ3@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
WH3_k127_1302007_1	240016.ABIZ01000001_gene4526	3.963e-10	63.0	COG2242@1|root,COG2242@2|Bacteria,46T8W@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
WH3_k127_13044560_4	96561.Dole_1704	1.387e-19	93.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_13044560_1	1297863.APJF01000004_gene348	4.473e-43	161.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2UCKH@28211|Alphaproteobacteria,3JY07@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
WH3_k127_13044560_3	637389.Acaty_c2094	1.216e-21	107.0	COG0392@1|root,COG0392@2|Bacteria,1MVZ8@1224|Proteobacteria,1SDDS@1236|Gammaproteobacteria,2NC9Y@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WH3_k127_13044560_6	1190603.AJYD01000095_gene3634	3.997e-08	59.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,1XXWR@135623|Vibrionales	135623|Vibrionales	J	COG1544 Ribosome-associated protein Y (PSrp-1)	yhbH	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
WH3_k127_13044560_2	314230.DSM3645_09087	5.215e-31	128.0	COG1762@1|root,COG1762@2|Bacteria,2IZ73@203682|Planctomycetes	203682|Planctomycetes	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	-	-	2.7.1.202	ko:K02768,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
WH3_k127_13044560_5	656519.Halsa_0189	1.431e-13	74.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,3WC24@53433|Halanaerobiales	186801|Clostridia	G	TIGRFAM Phosphotransferase System HPr (HPr) Family	ptsH	-	-	ko:K02784,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1,8.A.8.1.1	-	-	PTS-HPr
WH3_k127_13044560_0	1123242.JH636434_gene4060	2.384e-92	316.0	COG1080@1|root,COG1080@2|Bacteria,2IX08@203682|Planctomycetes	203682|Planctomycetes	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
WH3_k127_13098703_1	1168034.FH5T_04505	9.638e-181	572.0	COG0502@1|root,COG0502@2|Bacteria,4NEI7@976|Bacteroidetes,2FM8N@200643|Bacteroidia	976|Bacteroidetes	C	In Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and IscS	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
WH3_k127_13098703_0	335543.Sfum_1842	2.249e-181	578.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,42MFS@68525|delta/epsilon subdivisions,2WJPR@28221|Deltaproteobacteria,2MRBH@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
WH3_k127_13098703_2	335543.Sfum_1843	2.577e-73	251.0	COG0486@1|root,COG0486@2|Bacteria,1PM94@1224|Proteobacteria,42MYX@68525|delta/epsilon subdivisions,2WJE4@28221|Deltaproteobacteria,2MR3V@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	50S ribosome-binding GTPase	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
WH3_k127_13104373_0	886293.Sinac_4872	6.541e-78	273.0	COG0564@1|root,COG0564@2|Bacteria,2IXSI@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WH3_k127_13136525_0	595460.RRSWK_05060	6.321e-90	306.0	COG1520@1|root,COG1520@2|Bacteria,2IYEA@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
WH3_k127_13136525_1	1304284.L21TH_0118	3.249e-62	220.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia,36E72@31979|Clostridiaceae	186801|Clostridia	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WH3_k127_13138154_0	1268072.PSAB_20490	1.215e-15	83.0	2AUEM@1|root,31K2N@2|Bacteria,1UPSN@1239|Firmicutes,4IVA4@91061|Bacilli,26WJ8@186822|Paenibacillaceae	91061|Bacilli	S	Family of unknown function (DUF5309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5309
WH3_k127_13166421_1	234267.Acid_0302	6.116e-60	215.0	COG0602@1|root,COG0602@2|Bacteria,3Y2UA@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
WH3_k127_13166421_0	1449126.JQKL01000022_gene140	3.427e-145	471.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,267N3@186813|unclassified Clostridiales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WH3_k127_13268163_0	945713.IALB_2434	7.992e-66	229.0	COG1704@1|root,COG1704@2|Bacteria	2|Bacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
WH3_k127_13268163_1	945713.IALB_2435	1.469e-20	96.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	Rhomboid,zf-TFIIB
WH3_k127_13294326_0	1125863.JAFN01000001_gene353	9.534e-193	612.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
WH3_k127_13294326_1	338963.Pcar_1613	7.561e-144	465.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,43SCX@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
WH3_k127_13294430_1	1000565.METUNv1_03770	2.204e-41	164.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,2VUX2@28216|Betaproteobacteria	28216|Betaproteobacteria	M	glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_transf_7C,Glycos_transf_2,PIG-L
WH3_k127_13294430_0	102129.Lepto7375DRAFT_2443	6.572e-47	181.0	COG1216@1|root,COG1216@2|Bacteria,1GBJC@1117|Cyanobacteria	1117|Cyanobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH3_k127_13297535_0	1408226.T233_01592	1.272e-68	245.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,4AZ64@81852|Enterococcaceae	91061|Bacilli	D	Cellulose biosynthesis protein BcsQ	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
WH3_k127_13297535_1	1485545.JQLW01000005_gene869	1.984e-22	109.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria	1224|Proteobacteria	U	type IV pilus secretin PilQ	pilQ	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	-	ko:K02507,ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
WH3_k127_13312598_4	756067.MicvaDRAFT_2153	1.942e-20	106.0	COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria,1G463@1117|Cyanobacteria,1H97Y@1150|Oscillatoriales	1117|Cyanobacteria	MQ	PFAM Collagen-binding surface protein Cna-like, B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,SdrD_B
WH3_k127_13312598_3	1172190.M947_06400	1.141e-37	161.0	COG1470@1|root,COG3210@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,42NZJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	TIGRFAM filamentous haemagglutinin family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Glug,Haemagg_act
WH3_k127_13312598_2	886293.Sinac_4979	2.357e-55	198.0	COG0440@1|root,COG0440@2|Bacteria,2IZ6Q@203682|Planctomycetes	203682|Planctomycetes	E	Acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
WH3_k127_13312598_0	237368.SCABRO_03824	2.668e-210	667.0	COG0028@1|root,COG0028@2|Bacteria,2IXMU@203682|Planctomycetes	203682|Planctomycetes	H	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
WH3_k127_13312598_1	344747.PM8797T_32095	1.27e-110	363.0	COG1219@1|root,COG1219@2|Bacteria,2IXDS@203682|Planctomycetes	203682|Planctomycetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
WH3_k127_13326509_0	1235798.C817_02629	1.452e-81	295.0	COG3598@1|root,COG5519@1|root,COG3598@2|Bacteria,COG5519@2|Bacteria,1UIBK@1239|Firmicutes,24K1Q@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,Prim-Pol
WH3_k127_13326509_1	1123242.JH636435_gene1986	1.34e-08	59.0	2DFN0@1|root,2ZSD2@2|Bacteria,2J4C8@203682|Planctomycetes	203682|Planctomycetes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
WH3_k127_13333756_2	401526.TcarDRAFT_1603	6.092e-07	57.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4H5AC@909932|Negativicutes	909932|Negativicutes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
WH3_k127_13333756_0	1280706.AUJE01000007_gene2798	1.901e-54	196.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4H3ZR@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
WH3_k127_13333756_1	269797.Mbar_A3643	1.396e-15	85.0	COG0457@1|root,arCOG05195@1|root,arCOG03038@2157|Archaea,arCOG05195@2157|Archaea,2XUNW@28890|Euryarchaeota,2NAF9@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
WH3_k127_1333503_1	278963.ATWD01000001_gene2192	8.498e-05	53.0	COG1269@1|root,COG1269@2|Bacteria,3Y565@57723|Acidobacteria,2JMUB@204432|Acidobacteriia	204432|Acidobacteriia	C	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
WH3_k127_1333503_0	489825.LYNGBM3L_44960	6.504e-06	51.0	COG2244@1|root,COG2244@2|Bacteria,1FZXI@1117|Cyanobacteria,1H9D8@1150|Oscillatoriales	1117|Cyanobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
WH3_k127_13350911_0	1123320.KB889675_gene3952	2.549e-79	275.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria	201174|Actinobacteria	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
WH3_k127_13350911_1	929556.Solca_3943	1.225e-55	201.0	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,1IQEJ@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
WH3_k127_13379111_0	1121405.dsmv_3305	3.077e-45	180.0	COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,42N45@68525|delta/epsilon subdivisions,2WKUD@28221|Deltaproteobacteria,2MHZA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
WH3_k127_13379238_0	517417.Cpar_0065	4.793e-11	67.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
WH3_k127_13497278_1	335543.Sfum_0500	2.713e-55	197.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2WP3R@28221|Deltaproteobacteria,2MSCP@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
WH3_k127_13497278_0	720554.Clocl_1153	6.86e-142	462.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WGM9@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglycerate kinase	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
WH3_k127_13497278_2	537013.CLOSTMETH_02118	3.216e-35	139.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,3WISD@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WH3_k127_13498021_0	1142394.PSMK_25340	1.229e-136	447.0	COG0465@1|root,COG0465@2|Bacteria,2IWU2@203682|Planctomycetes	203682|Planctomycetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
WH3_k127_13498021_1	344747.PM8797T_14229	7.376e-21	98.0	COG2980@1|root,COG2980@2|Bacteria,2J05A@203682|Planctomycetes	203682|Planctomycetes	M	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
WH3_k127_13498021_2	452637.Oter_3602	4.304e-06	54.0	COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,46SYU@74201|Verrucomicrobia,3K7IV@414999|Opitutae	414999|Opitutae	S	Outer membrane lipoprotein	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	TPR_6
WH3_k127_13534400_0	1191523.MROS_0349	3.1e-160	511.0	COG0148@1|root,COG0148@2|Bacteria	2|Bacteria	G	phosphopyruvate hydratase activity	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
WH3_k127_13545263_0	1125863.JAFN01000001_gene2970	2.516e-12	79.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
WH3_k127_13573670_1	546271.Selsp_0934	4.168e-52	192.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4H2P5@909932|Negativicutes	909932|Negativicutes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
WH3_k127_13573670_2	330214.NIDE3291	4.614e-27	123.0	COG0859@1|root,COG0859@2|Bacteria,3J1E5@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
WH3_k127_13573670_3	1048339.KB913029_gene892	0.0002345	49.0	COG0745@1|root,COG0745@2|Bacteria,2IM7B@201174|Actinobacteria,4ET70@85013|Frankiales	201174|Actinobacteria	T	Response regulator receiver	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
WH3_k127_13573670_0	706587.Desti_2509	8.149e-90	304.0	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,1MX2U@1224|Proteobacteria,42QJC@68525|delta/epsilon subdivisions,2WPI2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_10,TPR_16,TPR_19,TPR_4,TPR_8
WH3_k127_13582014_1	1410676.JNKL01000020_gene1213	0.0002366	51.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1Y45C@135624|Aeromonadales	135624|Aeromonadales	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
WH3_k127_13582014_0	1142394.PSMK_29780	6.793e-66	235.0	COG0515@1|root,COG0515@2|Bacteria,2IZHV@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WH3_k127_13584287_2	351627.Csac_0204	2.64e-34	141.0	COG3693@1|root,COG3693@2|Bacteria,1UZWX@1239|Firmicutes,24BPR@186801|Clostridia	186801|Clostridia	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_10
WH3_k127_13584287_3	1123009.AUID01000024_gene1455	2.09e-27	117.0	2E12M@1|root,32WIA@2|Bacteria,1VD2B@1239|Firmicutes,24NKB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_13584287_0	1499967.BAYZ01000039_gene2222	7.941e-64	226.0	COG0558@1|root,COG0558@2|Bacteria,2NPXW@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.34	ko:K07291	ko00562,map00562	-	R09670	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WH3_k127_13584287_1	880073.Calab_0984	1.739e-53	198.0	COG0265@1|root,COG0265@2|Bacteria,2NQK9@2323|unclassified Bacteria	2|Bacteria	O	Trypsin	degQ	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WH3_k127_13608324_5	1345697.M493_00730	8.711e-09	59.0	COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HH4R@91061|Bacilli,1WEEW@129337|Geobacillus	91061|Bacilli	S	UvrB/uvrC motif	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
WH3_k127_13608324_4	546271.Selsp_1143	1.07e-14	79.0	COG0720@1|root,COG0720@2|Bacteria,1VAJX@1239|Firmicutes,4H58Z@909932|Negativicutes	909932|Negativicutes	H	queuosine biosynthesis protein QueD	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
WH3_k127_13608324_3	744872.Spica_2567	2.346e-16	82.0	COG0724@1|root,COG0724@2|Bacteria,2J8UF@203691|Spirochaetes	203691|Spirochaetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
WH3_k127_13608324_0	530564.Psta_0132	7.566e-52	186.0	COG2088@1|root,COG2088@2|Bacteria,2IZR8@203682|Planctomycetes	203682|Planctomycetes	D	Belongs to the SpoVG family	-	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
WH3_k127_13608324_2	634956.Geoth_0062	8.966e-40	161.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli,1WESF@129337|Geobacillus	91061|Bacilli	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096,M00582	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.29	-	iYO844.BSU00460	GHMP_kinases_C,GHMP_kinases_N
WH3_k127_13608324_1	530564.Psta_3740	2.64e-43	171.0	COG1200@1|root,COG1200@2|Bacteria,2IX1Q@203682|Planctomycetes	203682|Planctomycetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WH3_k127_13608918_1	247634.GPB2148_403	1.443e-16	82.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1J4PX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iEC55989_1330.EC55989_0819,iECO111_1330.ECO111_0837,iECO26_1355.ECO26_0902,iSDY_1059.SDY_0830	Aminotran_1_2
WH3_k127_13608918_0	1379698.RBG1_1C00001G1850	2.66e-36	149.0	COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria	2|Bacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WH3_k127_13669475_2	1142394.PSMK_15110	3.049e-06	59.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
WH3_k127_13669475_0	237368.SCABRO_02563	1.452e-53	194.0	COG2078@1|root,COG2078@2|Bacteria,2J349@203682|Planctomycetes	203682|Planctomycetes	S	AMMECR1	-	-	-	-	-	-	-	-	-	-	-	-	AMMECR1
WH3_k127_13669475_1	945713.IALB_0235	1.775e-32	128.0	COG1238@1|root,COG1238@2|Bacteria	2|Bacteria	I	metal cluster binding	MA20_20865	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
WH3_k127_13689704_1	273068.TTE2525	7.489e-42	158.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,42F1U@68295|Thermoanaerobacterales	186801|Clostridia	P	Belongs to the ABC transporter superfamily	appD	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WH3_k127_13689704_0	1201290.M902_1885	1.525e-75	264.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
WH3_k127_13689704_2	1303518.CCALI_01044	8.313e-16	79.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	oppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WH3_k127_1371216_0	162425.CADANIAP00005199	0.0002298	53.0	COG0457@1|root,KOG1840@2759|Eukaryota,38C2F@33154|Opisthokonta,3NYVZ@4751|Fungi,3QJJI@4890|Ascomycota,20AWC@147545|Eurotiomycetes,3S4I8@5042|Eurotiales	4751|Fungi	Z	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,PNP_UDP_1,Patatin,TPR_10,TPR_12,TPR_7,TPR_8
WH3_k127_13716349_0	1479237.JMLY01000001_gene893	4.848e-40	157.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,1S227@1236|Gammaproteobacteria,465SB@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
WH3_k127_13734648_0	1231241.Mc24_00794	2.18e-127	419.0	COG0282@1|root,COG0282@2|Bacteria,2GC1D@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
WH3_k127_13734648_1	243231.GSU1195	4.11e-22	99.0	COG1418@1|root,COG1418@2|Bacteria,1RK7K@1224|Proteobacteria,42SRK@68525|delta/epsilon subdivisions,2WP5I@28221|Deltaproteobacteria,43UQH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Metal-dependent phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
WH3_k127_13739791_0	1123508.JH636439_gene1482	1.291e-62	222.0	COG1212@1|root,COG1212@2|Bacteria,2IYWF@203682|Planctomycetes	203682|Planctomycetes	H	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
WH3_k127_13739791_1	1454010.JEOE01000012_gene1577	2.174e-20	103.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the carbohydrate kinase PfkB family	fruK	-	2.7.1.11,2.7.1.56	ko:K00882,ko:K16370	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00345	R00756,R02071,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
WH3_k127_13739791_2	760192.Halhy_1128	3.284e-05	48.0	COG3209@1|root,COG3209@2|Bacteria,4NFUE@976|Bacteroidetes,1INSI@117747|Sphingobacteriia	976|Bacteroidetes	M	COG3209 Rhs family protein	rhsA	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
WH3_k127_13743255_1	370438.PTH_2455	7.144e-14	72.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,261M6@186807|Peptococcaceae	186801|Clostridia	S	PFAM Fic DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
WH3_k127_13743255_0	56780.SYN_02589	0.0	1255.0	COG0458@1|root,COG0458@2|Bacteria,1NPMZ@1224|Proteobacteria,42NF3@68525|delta/epsilon subdivisions,2WM4C@28221|Deltaproteobacteria,2MQ8X@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthetase large chain, oligomerisation	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0661	CPSase_L_D2,CPSase_L_D3,MGS
WH3_k127_13765666_2	929506.CbC4_2322	1.888e-05	50.0	COG0840@1|root,COG4936@1|root,COG0840@2|Bacteria,COG4936@2|Bacteria,1UE0Y@1239|Firmicutes,24AR0@186801|Clostridia,36DNI@31979|Clostridiaceae	186801|Clostridia	KNT	chemotaxis	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,PocR
WH3_k127_13765666_0	886293.Sinac_7540	3.127e-197	626.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2IX43@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
WH3_k127_13765666_1	243090.RB5346	1.236e-41	158.0	COG1943@1|root,COG1943@2|Bacteria,2J0GJ@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WH3_k127_1380056_1	653733.Selin_2111	1.633e-24	118.0	291BV@1|root,2ZNYU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_1380056_0	411477.PARMER_02918	2.357e-83	287.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,2FNX9@200643|Bacteroidia,22XHF@171551|Porphyromonadaceae	976|Bacteroidetes	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
WH3_k127_1380056_2	595460.RRSWK_01971	9.097e-12	72.0	28Z0A@1|root,2ZKSY@2|Bacteria,2J4HE@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_1380591_0	484018.BACPLE_01017	1.479e-64	231.0	2FB4Y@1|root,343B9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_1380591_1	1307761.L21SP2_3408	2.129e-33	139.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.202,2.7.13.3	ko:K02768,ko:K02769,ko:K02770,ko:K02806,ko:K07646	ko00051,ko01100,ko01120,ko02020,ko02060,map00051,map01100,map01120,map02020,map02060	M00273,M00454	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022	4.A.2.1	-	-	KdpD,Na_H_Exchanger,PTS_EIIA_2
WH3_k127_1395289_0	1121406.JAEX01000022_gene1423	3.811e-08	61.0	COG3103@1|root,COG3103@2|Bacteria,1NC3E@1224|Proteobacteria,42VDV@68525|delta/epsilon subdivisions,2X1T3@28221|Deltaproteobacteria,2MFME@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM SH3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_1422934_1	530564.Psta_1167	6.17e-100	354.0	COG3119@1|root,COG3119@2|Bacteria	530564.Psta_1167|-	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_1422934_0	1349822.NSB1T_08710	1.864e-112	384.0	2DBP8@1|root,2ZA84@2|Bacteria,4NKHW@976|Bacteroidetes,2FQDJ@200643|Bacteroidia,22ZNZ@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_1426448_1	926692.AZYG01000040_gene1577	5.059e-36	140.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3WARV@53433|Halanaerobiales	186801|Clostridia	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
WH3_k127_1426448_0	565034.BHWA1_02143	2.023e-50	186.0	COG0201@1|root,COG0201@2|Bacteria,2J5BH@203691|Spirochaetes	203691|Spirochaetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
WH3_k127_1426454_0	1120998.AUFC01000025_gene824	1.004e-81	276.0	COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,249FR@186801|Clostridia,3WCJA@538999|Clostridiales incertae sedis	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH3_k127_1426454_1	1120998.AUFC01000025_gene823	1.401e-47	173.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,24N57@186801|Clostridia,3WDMB@538999|Clostridiales incertae sedis	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
WH3_k127_1426454_2	97138.C820_00711	2.038e-38	148.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia,36DU9@31979|Clostridiaceae	186801|Clostridia	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
WH3_k127_1484959_2	930169.B5T_03751	7.313e-15	82.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1XI3R@135619|Oceanospirillales	135619|Oceanospirillales	NU	secretion pathway protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
WH3_k127_1484959_0	1125863.JAFN01000001_gene2969	1.203e-164	535.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
WH3_k127_1484959_1	391625.PPSIR1_25856	4.613e-61	224.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
WH3_k127_1529400_0	1499967.BAYZ01000095_gene4213	2.12e-132	434.0	COG0364@1|root,COG0364@2|Bacteria,2NNUR@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iIT341.HP1101	G6PD_C,G6PD_N
WH3_k127_1530017_0	980584.AFPB01000179_gene3452	2.389e-147	479.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,1HXT4@117743|Flavobacteriia,405TV@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	U	SRP54-type protein, helical bundle domain	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
WH3_k127_1536819_0	1142394.PSMK_15840	1.292e-63	227.0	COG0134@1|root,COG0134@2|Bacteria,2IX3M@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
WH3_k127_1536819_2	1379698.RBG1_1C00001G0404	6.745e-07	57.0	2EAFJ@1|root,334IY@2|Bacteria,2NRZR@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
WH3_k127_1536819_1	1226322.HMPREF1545_00370	2.18e-15	78.0	COG1708@1|root,COG1708@2|Bacteria,1VIRD@1239|Firmicutes,24S99@186801|Clostridia	186801|Clostridia	S	PFAM DNA polymerase, beta domain protein region	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
WH3_k127_1551971_0	319225.Plut_0082	2.337e-92	319.0	COG3014@1|root,COG3014@2|Bacteria,1FFNE@1090|Chlorobi	1090|Chlorobi	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
WH3_k127_1551971_1	319225.Plut_0084	4.423e-12	69.0	COG3417@1|root,COG3417@2|Bacteria	2|Bacteria	M	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
WH3_k127_1648913_0	1210884.HG799476_gene15402	6.73e-91	307.0	COG0002@1|root,COG0002@2|Bacteria,2IXTC@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
WH3_k127_1648913_1	756272.Plabr_3639	1.771e-36	143.0	COG0103@1|root,COG0103@2|Bacteria,2J01J@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
WH3_k127_1651961_1	398767.Glov_1264	7.367e-20	91.0	COG0457@1|root,COG0457@2|Bacteria,1RKYJ@1224|Proteobacteria,42SSS@68525|delta/epsilon subdivisions,2WPW3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
WH3_k127_1651961_0	338966.Ppro_0649	2.17e-98	331.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,42RF4@68525|delta/epsilon subdivisions,2WPIV@28221|Deltaproteobacteria,43TWB@69541|Desulfuromonadales	28221|Deltaproteobacteria	GK	PFAM ROK family protein	glkA	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
WH3_k127_1651961_2	398767.Glov_1262	1.72e-12	68.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	malic protein domain protein	mdh	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
WH3_k127_1668132_0	452637.Oter_2237	1.043e-87	293.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	f42a	-	-	-	-	-	-	-	-	-	-	-	Band_7
WH3_k127_1668132_2	452637.Oter_2236	1.49e-13	72.0	COG4877@1|root,COG4877@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
WH3_k127_1668132_1	886293.Sinac_1401	1.396e-79	271.0	COG1403@1|root,COG1403@2|Bacteria,2IXXW@203682|Planctomycetes	203682|Planctomycetes	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
WH3_k127_1674444_1	1123371.ATXH01000023_gene922	5.924e-30	120.0	COG2759@1|root,COG2759@2|Bacteria,2GH8C@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Formate--tetrahydrofolate ligase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
WH3_k127_1674444_0	697281.Mahau_0525	5.461e-99	332.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,247Z9@186801|Clostridia,42GQ8@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Radical SAM domain protein	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
WH3_k127_1682096_1	886293.Sinac_6978	3.416e-74	256.0	COG0488@1|root,COG0488@2|Bacteria,2IX59@203682|Planctomycetes	203682|Planctomycetes	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WH3_k127_1682096_0	316067.Geob_2677	7.67e-151	487.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,43U14@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
WH3_k127_1682096_2	404589.Anae109_3588	5.75e-19	89.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria	1224|Proteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG_1	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
WH3_k127_1692690_2	1329516.JPST01000001_gene948	4.009e-126	413.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,27AW4@186824|Thermoactinomycetaceae	91061|Bacilli	J	tRNA synthetases class I (W and Y)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
WH3_k127_1692690_0	243090.RB5084	1.635e-222	709.0	COG1053@1|root,COG1053@2|Bacteria,2J4ZP@203682|Planctomycetes	203682|Planctomycetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
WH3_k127_1692690_1	502025.Hoch_6504	1.671e-181	573.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,42MHS@68525|delta/epsilon subdivisions,2WJQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Saccharopine dehydrogenase	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0902	Sacchrp_dh_C,Sacchrp_dh_NADP
WH3_k127_1703743_0	717785.HYPMC_3216	1.181e-35	136.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2TS6U@28211|Alphaproteobacteria,3N6J6@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	sun1	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F
WH3_k127_1703743_2	1123517.JOMR01000001_gene797	0.0001502	50.0	COG3190@1|root,COG3190@2|Bacteria,1N79Z@1224|Proteobacteria,1SCKP@1236|Gammaproteobacteria,461DG@72273|Thiotrichales	72273|Thiotrichales	N	PFAM flagellar biosynthesis protein, FliO	-	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
WH3_k127_1703743_1	644282.Deba_1237	9.026e-06	49.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42PB5@68525|delta/epsilon subdivisions,2WJRE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	motA-2	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
WH3_k127_173135_0	449447.MAE_25830	1.014e-51	189.0	COG1971@1|root,COG1971@2|Bacteria,1G66H@1117|Cyanobacteria	1117|Cyanobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
WH3_k127_173135_1	926569.ANT_16820	4.778e-21	96.0	COG1408@1|root,COG1408@2|Bacteria,2G6VC@200795|Chloroflexi	200795|Chloroflexi	S	PFAM metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
WH3_k127_1734983_0	1396141.BATP01000027_gene1160	1.661e-25	124.0	COG2273@1|root,COG2755@1|root,COG3064@1|root,COG3291@1|root,COG5306@1|root,COG2273@2|Bacteria,COG2755@2|Bacteria,COG3064@2|Bacteria,COG3291@2|Bacteria,COG5306@2|Bacteria,46X9M@74201|Verrucomicrobia,2IV4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGM	Peptidase M60-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,M60-like_N,PA14,Peptidase_M60
WH3_k127_1757789_1	641491.DND132_0546	1.912e-59	210.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,2M90H@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
WH3_k127_1757789_0	1089553.Tph_c22610	2.164e-80	278.0	COG0731@1|root,COG0731@2|Bacteria,1TSYW@1239|Firmicutes,24CEP@186801|Clostridia,42ID6@68295|Thermoanaerobacterales	186801|Clostridia	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
WH3_k127_179700_1	903818.KI912269_gene60	4.908e-86	290.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria	2|Bacteria	C	iron-sulfur cluster assembly	-	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_20,Fer4_6,Fer4_7,Fer4_9,NADH-G_4Fe-4S_3,Pyr_redox_2
WH3_k127_179700_0	1121468.AUBR01000009_gene2104	8.155e-217	679.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,42EM7@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding	-	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
WH3_k127_1825783_0	379066.GAU_2217	1.163e-41	168.0	COG0612@1|root,COG0612@2|Bacteria,1ZT6X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WH3_k127_1863775_0	398767.Glov_3322	8.036e-183	582.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2WIPF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM glycosyl transferase, family 35	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
WH3_k127_1901756_0	886293.Sinac_2378	3.614e-17	96.0	COG2911@1|root,COG2982@1|root,COG2911@2|Bacteria,COG2982@2|Bacteria,2J50C@203682|Planctomycetes	203682|Planctomycetes	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_190840_1	1406840.Q763_17395	4.869e-24	109.0	COG3291@1|root,COG3291@2|Bacteria,4PI2H@976|Bacteroidetes,1IA3E@117743|Flavobacteriia,2NXN5@237|Flavobacterium	976|Bacteroidetes	DZ	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
WH3_k127_190840_0	642492.Clole_3454	4.289e-27	111.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WH3_k127_1913673_2	886293.Sinac_0249	3.568e-20	106.0	COG1595@1|root,COG1595@2|Bacteria,2IZWS@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
WH3_k127_1913673_0	1219084.AP014508_gene1727	8.506e-68	237.0	COG1515@1|root,COG1515@2|Bacteria,2GCUF@200918|Thermotogae	200918|Thermotogae	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
WH3_k127_1913673_1	631362.Thi970DRAFT_03118	3.021e-49	180.0	COG1848@1|root,COG1848@2|Bacteria,1N3CQ@1224|Proteobacteria,1S919@1236|Gammaproteobacteria,1WYY3@135613|Chromatiales	135613|Chromatiales	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WH3_k127_1913673_3	1121129.KB903372_gene340	5.841e-08	56.0	COG1506@1|root,COG1506@2|Bacteria,4NE2Q@976|Bacteroidetes,2FPZU@200643|Bacteroidia,22VXZ@171551|Porphyromonadaceae	976|Bacteroidetes	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
WH3_k127_1927690_0	545694.TREPR_1265	8.089e-24	104.0	COG2086@1|root,COG2086@2|Bacteria,2J6CP@203691|Spirochaetes	203691|Spirochaetes	C	Electron transfer flavoprotein	etfB	-	1.3.1.108	ko:K03521,ko:K22431	-	-	-	-	ko00000,ko01000	-	-	-	ETF
WH3_k127_194439_1	575540.Isop_1330	3.655e-50	182.0	COG1082@1|root,COG1082@2|Bacteria,2IXXS@203682|Planctomycetes	203682|Planctomycetes	G	PFAM AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
WH3_k127_194439_0	1403819.BATR01000117_gene4036	1.744e-143	463.0	COG0673@1|root,COG0673@2|Bacteria,46TXS@74201|Verrucomicrobia,2ITIU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WH3_k127_1965015_1	1167006.UWK_03462	1.436e-05	49.0	COG4206@1|root,COG4206@2|Bacteria,1QTTF@1224|Proteobacteria,43D2X@68525|delta/epsilon subdivisions,2X8A2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug
WH3_k127_1965015_0	247490.KSU1_C0017	2.398e-77	270.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_25,Methyltransf_31,rRNA_methylase
WH3_k127_1984311_1	96561.Dole_2003	3.085e-99	330.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,42MVD@68525|delta/epsilon subdivisions,2WIY3@28221|Deltaproteobacteria,2MIPS@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
WH3_k127_1984311_2	1232437.KL661958_gene2873	2.624e-15	82.0	COG3090@1|root,COG3090@2|Bacteria,1N9EF@1224|Proteobacteria,42WJB@68525|delta/epsilon subdivisions,2WRDN@28221|Deltaproteobacteria,2MK1K@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
WH3_k127_1984311_0	96561.Dole_2001	4.545e-152	494.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42M9N@68525|delta/epsilon subdivisions,2WIZR@28221|Deltaproteobacteria,2MHKG@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
WH3_k127_1984311_3	335543.Sfum_0180	1.47e-14	80.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria,2MQN7@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM Universal stress protein family	usp-2	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
WH3_k127_1992052_0	357804.Ping_1785	1.227e-62	220.0	COG3449@1|root,COG3449@2|Bacteria,1RF2U@1224|Proteobacteria,1S2JU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
WH3_k127_1992052_1	42256.RradSPS_1974	2.653e-35	143.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CPVX@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
WH3_k127_1992052_2	751944.HALDL1_03910	0.0001283	53.0	arCOG02540@1|root,arCOG04500@1|root,arCOG10954@1|root,arCOG02540@2157|Archaea,arCOG04500@2157|Archaea,arCOG10954@2157|Archaea,2XWGB@28890|Euryarchaeota,23UX2@183963|Halobacteria	183963|Halobacteria	M	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2030667_0	264732.Moth_2477	1.812e-80	280.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,42FGS@68295|Thermoanaerobacterales	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	engD	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
WH3_k127_2030667_3	3649.evm.model.supercontig_0.141	1.717e-14	81.0	COG0740@1|root,KOG0840@2759|Eukaryota,37J0P@33090|Viridiplantae,3GCKS@35493|Streptophyta,3HRKY@3699|Brassicales	35493|Streptophyta	O	ATP-dependent Clp protease proteolytic subunit	-	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0008270,GO:0009368,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009840,GO:0016020,GO:0031976,GO:0031984,GO:0032991,GO:0034357,GO:0042651,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0055035	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
WH3_k127_2030667_1	882.DVU_2548	3.337e-67	234.0	COG1182@1|root,COG1182@2|Bacteria,1NJP3@1224|Proteobacteria,42UST@68525|delta/epsilon subdivisions,2WR0H@28221|Deltaproteobacteria,2MBN8@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity	azoR	-	-	ko:K01118	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_2
WH3_k127_2030667_2	886293.Sinac_5294	6.73e-30	124.0	COG0763@1|root,COG0763@2|Bacteria,2IXXN@203682|Planctomycetes	203682|Planctomycetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
WH3_k127_2031745_0	439235.Dalk_2288	7.697e-38	157.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42R71@68525|delta/epsilon subdivisions,2WMW5@28221|Deltaproteobacteria,2MPW6@213118|Desulfobacterales	28221|Deltaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,RHS,RHS_repeat,Transglut_core
WH3_k127_2075192_0	143224.JQMD01000002_gene257	1.933e-150	488.0	COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,1I886@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WH3_k127_2077742_1	756272.Plabr_3423	5.13e-127	421.0	COG0621@1|root,COG0621@2|Bacteria,2IWTE@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
WH3_k127_2077742_3	1122228.AQXR01000011_gene377	8.242e-25	111.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4CZ36@85004|Bifidobacteriales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WH3_k127_2077742_0	4006.Lus10033978	6.127e-147	475.0	COG0137@1|root,KOG1706@2759|Eukaryota,37QUX@33090|Viridiplantae,3G8Y6@35493|Streptophyta,4JEKX@91835|fabids	35493|Streptophyta	E	Argininosuccinate synthase	-	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
WH3_k127_2077742_2	1142394.PSMK_18480	7.978e-30	127.0	COG1989@1|root,COG1989@2|Bacteria,2IZQ8@203682|Planctomycetes	203682|Planctomycetes	NOU	Bacterial Peptidase A24 N-terminal domain	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
WH3_k127_2092304_0	744872.Spica_2651	1.256e-145	473.0	COG1208@1|root,COG1208@2|Bacteria,2J5V0@203691|Spirochaetes	203691|Spirochaetes	JM	Domain of unknown function (DUF4954)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4954
WH3_k127_2092304_2	1123242.JH636437_gene6133	8.859e-97	327.0	COG2222@1|root,COG2222@2|Bacteria,2J1SP@203682|Planctomycetes	203682|Planctomycetes	M	sugar isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2092304_1	1410618.JNKI01000002_gene1048	1.053e-99	331.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4H1ZY@909932|Negativicutes	909932|Negativicutes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
WH3_k127_2092304_3	1487923.DP73_14815	6.023e-51	187.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,260M0@186807|Peptococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
WH3_k127_2103636_0	1105031.HMPREF1141_3287	6.002e-14	87.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,36E5E@31979|Clostridiaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
WH3_k127_2156809_0	443143.GM18_0314	3.405e-25	108.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WJ2H@28221|Deltaproteobacteria,43U7R@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methionine synthase B12-binding module cap domain protein	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
WH3_k127_2170800_0	1142394.PSMK_15660	9.61e-45	178.0	COG3147@1|root,COG3147@2|Bacteria,2IXFB@203682|Planctomycetes	203682|Planctomycetes	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2170800_1	1142394.PSMK_15650	3.183e-09	64.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
WH3_k127_2186191_0	269799.Gmet_2892	6.018e-97	323.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42MCE@68525|delta/epsilon subdivisions,2WIYP@28221|Deltaproteobacteria,43U7K@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
WH3_k127_2186191_2	309801.trd_1295	1.91e-25	115.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi,27XGX@189775|Thermomicrobia	189775|Thermomicrobia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WH3_k127_2186191_1	383372.Rcas_0758	1.288e-49	182.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WH3_k127_2202987_0	547042.BACCOPRO_00046	0.000148	51.0	2ASCR@1|root,31HS3@2|Bacteria,4NQ81@976|Bacteroidetes,2G3DQ@200643|Bacteroidia,4AWE1@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
WH3_k127_2238666_1	999419.HMPREF1077_03358	1.333e-21	99.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,2FMMF@200643|Bacteroidia,22XE8@171551|Porphyromonadaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase,Glyco_hydro_92
WH3_k127_2238666_0	595460.RRSWK_00276	1.52e-137	449.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9	ko:K00845,ko:K13967,ko:K19979,ko:K20433	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko00525,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map00525,map01100,map01110,map01120,map01130,map01200	M00001,M00549,M00814,M00815	R00299,R01600,R01786,R02087,R02705,R11185,R11234	RC00002,RC00017,RC00290	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
WH3_k127_2238666_2	1191523.MROS_1583	3.234e-17	83.0	COG0738@1|root,COG0738@2|Bacteria	2|Bacteria	G	Major facilitator superfamily	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
WH3_k127_2247304_0	344747.PM8797T_11234	1.508e-05	53.0	COG2165@1|root,COG2165@2|Bacteria,2J10X@203682|Planctomycetes	203682|Planctomycetes	U	Pfam:N_methyl_2	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
WH3_k127_2252785_0	344747.PM8797T_09134	4.785e-26	111.0	COG1695@1|root,COG1695@2|Bacteria,2J1J6@203682|Planctomycetes	203682|Planctomycetes	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WH3_k127_2255410_1	118166.JH976537_gene4274	1.166e-18	96.0	COG3216@1|root,COG3216@2|Bacteria,1G7YZ@1117|Cyanobacteria,1HCA8@1150|Oscillatoriales	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
WH3_k127_2255410_0	1121396.KB893073_gene2962	4.461e-47	184.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,43AFG@68525|delta/epsilon subdivisions,2WKA9@28221|Deltaproteobacteria,2MI8V@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WH3_k127_231053_2	586416.GZ22_10155	1.213e-15	79.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HADG@91061|Bacilli	91061|Bacilli	HP	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components	fhuC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
WH3_k127_231053_1	530564.Psta_0921	2.699e-23	110.0	COG1734@1|root,COG1734@2|Bacteria,2J04D@203682|Planctomycetes	203682|Planctomycetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
WH3_k127_231053_3	1046724.KB889908_gene910	1.255e-09	62.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,1SC7M@1236|Gammaproteobacteria,468WS@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
WH3_k127_231053_0	1267535.KB906767_gene720	2.64e-34	141.0	COG0760@1|root,COG0760@2|Bacteria,3Y8EB@57723|Acidobacteria,2JNN9@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM PPIC-type	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
WH3_k127_2331692_4	1313304.CALK_1773	6.397e-16	91.0	COG1267@1|root,COG1267@2|Bacteria	2|Bacteria	I	phosphatidylglycerophosphatase activity	pgpA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0195,iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520	PgpA
WH3_k127_2331692_2	292563.Cyast_1582	6.099e-47	186.0	COG1968@1|root,COG1968@2|Bacteria,1GC76@1117|Cyanobacteria	1117|Cyanobacteria	V	Bacitracin resistance protein BacA	-	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
WH3_k127_2331692_0	756272.Plabr_3360	6.224e-209	666.0	COG0445@1|root,COG0445@2|Bacteria,2IXGA@203682|Planctomycetes	203682|Planctomycetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
WH3_k127_2331692_3	1267535.KB906767_gene3790	5.272e-30	123.0	COG0736@1|root,COG0736@2|Bacteria,3Y590@57723|Acidobacteria	57723|Acidobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
WH3_k127_2331692_5	1499967.BAYZ01000122_gene3388	1.288e-07	63.0	COG0760@1|root,COG0760@2|Bacteria,2NPQV@2323|unclassified Bacteria	2|Bacteria	O	PPIC-type PPIASE domain	surA	-	5.2.1.8	ko:K02597,ko:K03769,ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
WH3_k127_2331692_1	1123508.JH636443_gene5095	1.03e-178	574.0	COG1197@1|root,COG1197@2|Bacteria,2IWV4@203682|Planctomycetes	203682|Planctomycetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WH3_k127_2333098_0	385682.AFSL01000027_gene616	1.348e-45	171.0	COG1051@1|root,COG1051@2|Bacteria,4NP2X@976|Bacteroidetes,2FMSZ@200643|Bacteroidia,3XIKW@558415|Marinilabiliaceae	976|Bacteroidetes	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,zf-NADH-PPase
WH3_k127_2357327_1	1123508.JH636440_gene2149	3.017e-30	124.0	COG1109@1|root,COG1109@2|Bacteria,2IXRS@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WH3_k127_2357327_0	1163617.SCD_n00151	1.056e-60	218.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VRSR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2238)	yjdF	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
WH3_k127_2357327_3	886293.Sinac_6085	3.459e-11	68.0	COG1793@1|root,COG1793@2|Bacteria,2J558@203682|Planctomycetes	203682|Planctomycetes	L	DNA polymerase Ligase (LigD)	-	-	-	-	-	-	-	-	-	-	-	-	LigD_N
WH3_k127_2357327_2	1121335.Clst_1242	1.596e-26	109.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,3WGX7@541000|Ruminococcaceae	186801|Clostridia	C	PFAM Phosphate acetyl butaryl transferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
WH3_k127_2372195_2	158189.SpiBuddy_1411	2.794e-08	56.0	COG0691@1|root,COG0691@2|Bacteria,2J78Q@203691|Spirochaetes	203691|Spirochaetes	J	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
WH3_k127_2372195_0	582515.KR51_00021740	7.931e-21	100.0	296NU@1|root,2ZTXX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2372195_1	375286.mma_0138	8.115e-21	94.0	COG3296@1|root,COG3296@2|Bacteria,1N4ZK@1224|Proteobacteria,2VWRG@28216|Betaproteobacteria,477FS@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
WH3_k127_239668_5	1123508.JH636445_gene6804	8.271e-22	99.0	COG1825@1|root,COG1825@2|Bacteria,2J050@203682|Planctomycetes	203682|Planctomycetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
WH3_k127_239668_0	247490.KSU1_B0544	8.012e-111	368.0	COG0462@1|root,COG0462@2|Bacteria,2IXI0@203682|Planctomycetes	203682|Planctomycetes	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
WH3_k127_239668_1	35841.BT1A1_0051	7.15e-87	298.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,1ZAVH@1386|Bacillus	91061|Bacilli	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
WH3_k127_239668_3	382464.ABSI01000010_gene3441	5.958e-65	230.0	COG2197@1|root,COG2197@2|Bacteria,46V5Z@74201|Verrucomicrobia,2IUBG@203494|Verrucomicrobiae	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH3_k127_239668_2	909663.KI867150_gene1026	1.65e-66	245.0	COG2202@1|root,COG3829@1|root,COG4585@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,1N0Y7@1224|Proteobacteria	1224|Proteobacteria	T	PFAM ATP-binding region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,MASE1,PAS
WH3_k127_239668_4	1123392.AQWL01000003_gene190	2.313e-33	137.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,2VUZW@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
WH3_k127_2397675_1	237368.SCABRO_03910	3.246e-07	61.0	2CFWI@1|root,32S2N@2|Bacteria,2J08K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2397675_0	1227349.C170_28533	3.352e-25	106.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,26SH5@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WH3_k127_241065_0	575540.Isop_2430	3.481e-35	141.0	2EQKH@1|root,33I6I@2|Bacteria,2J1DT@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2411788_0	1123242.JH636435_gene2775	9.985e-204	645.0	COG0514@1|root,COG0514@2|Bacteria,2IX4R@203682|Planctomycetes	203682|Planctomycetes	L	DEAD DEAH box helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
WH3_k127_2414100_0	1232437.KL662042_gene2024	1.435e-46	175.0	COG4122@1|root,COG5423@1|root,COG4122@2|Bacteria,COG5423@2|Bacteria,1QWN3@1224|Proteobacteria,42Q2N@68525|delta/epsilon subdivisions,2WM7P@28221|Deltaproteobacteria,2MIYM@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284,Dimerisation2,Methyltransf_2
WH3_k127_2414100_1	635013.TherJR_0545	9.967e-20	95.0	COG1032@1|root,COG1032@2|Bacteria,1UZJU@1239|Firmicutes,24AV2@186801|Clostridia,263VN@186807|Peptococcaceae	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
WH3_k127_2425685_0	1379698.RBG1_1C00001G0415	1.403e-76	269.0	COG5316@1|root,COG5316@2|Bacteria,2NPBR@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
WH3_k127_2431008_3	452637.Oter_3827	2.747e-56	198.0	COG0057@1|root,COG0057@2|Bacteria,46S59@74201|Verrucomicrobia,3K77U@414999|Opitutae	414999|Opitutae	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
WH3_k127_2431008_2	1125863.JAFN01000001_gene2268	1.496e-106	356.0	COG1363@1|root,COG1363@2|Bacteria,1MXEU@1224|Proteobacteria,42P13@68525|delta/epsilon subdivisions,2WMM6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
WH3_k127_2431008_0	671143.DAMO_2651	2.222e-238	755.0	COG0021@1|root,COG0021@2|Bacteria,2NS3T@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
WH3_k127_2431008_1	1142394.PSMK_11030	5.738e-143	468.0	COG0285@1|root,COG0285@2|Bacteria,2IX24@203682|Planctomycetes	203682|Planctomycetes	H	folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
WH3_k127_2431008_4	338966.Ppro_1209	8.868e-08	62.0	2BCS0@1|root,32VCH@2|Bacteria,1NC4G@1224|Proteobacteria,43BIY@68525|delta/epsilon subdivisions,2X6XE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2431008_5	1356852.N008_00195	2.814e-06	55.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,47P7K@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
WH3_k127_2437502_1	1121451.DESAM_10289	1.009e-73	248.0	COG0827@1|root,COG0827@2|Bacteria,1N2RX@1224|Proteobacteria,42PVK@68525|delta/epsilon subdivisions,2WK73@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM BsuBIPstI restriction endonuclease domain protein	-	-	3.1.21.4	ko:K01155	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	BsuBI_PstI_RE
WH3_k127_2437502_0	28072.Nos7524_2289	6.708e-95	323.0	COG0079@1|root,COG0079@2|Bacteria,1FZV3@1117|Cyanobacteria,1HK2F@1161|Nostocales	1117|Cyanobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iJN678.hisC	Aminotran_1_2
WH3_k127_2437502_2	237368.SCABRO_00779	3.484e-65	228.0	COG0131@1|root,COG0131@2|Bacteria,2IYU4@203682|Planctomycetes	203682|Planctomycetes	E	imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
WH3_k127_2437502_3	75379.Tint_1688	6.669e-48	177.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,1KKK3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
WH3_k127_2500495_0	1249627.D779_3411	7.107e-63	224.0	COG2253@1|root,COG2253@2|Bacteria,1NJT9@1224|Proteobacteria,1S0YI@1236|Gammaproteobacteria,1WXVW@135613|Chromatiales	135613|Chromatiales	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
WH3_k127_2500495_1	335543.Sfum_2055	2.485e-52	191.0	COG5340@1|root,COG5340@2|Bacteria,1P6MT@1224|Proteobacteria,42SXD@68525|delta/epsilon subdivisions,2WP1U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
WH3_k127_2508562_0	344747.PM8797T_02639	6.625e-81	281.0	COG0642@1|root,COG1352@1|root,COG1352@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	cheR4	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HWE_HK,HisKA,PAS_10,PAS_3,PAS_4,Response_reg
WH3_k127_2511093_1	886293.Sinac_1366	1.391e-40	155.0	COG0331@1|root,COG0331@2|Bacteria,2IXX2@203682|Planctomycetes	203682|Planctomycetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
WH3_k127_2511093_0	443143.GM18_3079	9.272e-73	252.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,43S1E@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH-2	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WH3_k127_2542411_0	326427.Cagg_1016	6.887e-86	299.0	COG0260@1|root,COG0260@2|Bacteria,2G617@200795|Chloroflexi,37528@32061|Chloroflexia	32061|Chloroflexia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
WH3_k127_2543052_0	247490.KSU1_D0820	1.572e-160	530.0	COG0532@1|root,COG0532@2|Bacteria,2IXYU@203682|Planctomycetes	203682|Planctomycetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
WH3_k127_2554195_0	1396141.BATP01000060_gene4657	1.524e-24	119.0	COG2010@1|root,COG2312@1|root,COG3204@1|root,COG2010@2|Bacteria,COG2312@2|Bacteria,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,Fn3_assoc,LTD,Laminin_G_3
WH3_k127_2578869_2	192952.MM_2006	4.383e-25	110.0	COG0573@1|root,arCOG00167@2157|Archaea,2XTYD@28890|Euryarchaeota,2NBPF@224756|Methanomicrobia	224756|Methanomicrobia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WH3_k127_2578869_1	926569.ANT_02630	8.054e-73	255.0	COG0226@1|root,COG0226@2|Bacteria,2G7T2@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
WH3_k127_2578869_0	1123274.KB899416_gene2670	1.992e-145	472.0	COG0019@1|root,COG0019@2|Bacteria,2J5HV@203691|Spirochaetes	203691|Spirochaetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
WH3_k127_2583314_0	497964.CfE428DRAFT_2394	8.489e-76	270.0	COG1520@1|root,COG1520@2|Bacteria,46U6I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
WH3_k127_2583314_1	138119.DSY1826	7.367e-09	66.0	COG0457@1|root,COG3118@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,1UUYP@1239|Firmicutes,24BRK@186801|Clostridia,2610N@186807|Peptococcaceae	186801|Clostridia	O	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_8
WH3_k127_2600873_0	296591.Bpro_4842	8.411e-50	192.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MUDN@1224|Proteobacteria,2VHMC@28216|Betaproteobacteria,4AA42@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM beta-lactamase domain protein	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WH3_k127_2617467_0	443598.AUFA01000013_gene6643	2.566e-49	181.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,3JY1U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
WH3_k127_2637764_1	760192.Halhy_1533	6.45e-68	234.0	COG3828@1|root,COG3828@2|Bacteria,4NEWH@976|Bacteroidetes,1IR1M@117747|Sphingobacteriia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
WH3_k127_2637764_0	926549.KI421517_gene2823	1.14e-207	655.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WH3_k127_2639807_0	1121405.dsmv_0453	5.459e-123	402.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42M9N@68525|delta/epsilon subdivisions,2WIZR@28221|Deltaproteobacteria,2MIUJ@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
WH3_k127_2639807_2	166318.Syn8016DRAFT_1041	2.299e-21	96.0	COG3450@1|root,COG3450@2|Bacteria,1G7YR@1117|Cyanobacteria,1H18F@1129|Synechococcus	1117|Cyanobacteria	S	enzyme of the cupin superfamily	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
WH3_k127_2639807_1	744872.Spica_2679	1.906e-101	338.0	COG0647@1|root,COG0647@2|Bacteria,2J6X3@203691|Spirochaetes	203691|Spirochaetes	G	Belongs to the HAD-like hydrolase superfamily	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
WH3_k127_2639807_3	1121024.AUCD01000001_gene1685	0.0002263	45.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,27G1X@186828|Carnobacteriaceae	91061|Bacilli	T	Transcriptional regulatory protein, C terminal	resD	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WH3_k127_2735242_0	635013.TherJR_1005	2.84e-53	202.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,260SC@186807|Peptococcaceae	186801|Clostridia	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
WH3_k127_2759396_0	1385511.N783_07635	7.142e-139	462.0	COG2304@1|root,COG2304@2|Bacteria,1TSU7@1239|Firmicutes,4HPXN@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
WH3_k127_2759396_1	744872.Spica_0095	2.253e-22	100.0	COG1373@1|root,COG1373@2|Bacteria,2J5MK@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WH3_k127_276993_0	595460.RRSWK_01774	1.415e-26	120.0	COG1295@1|root,COG1295@2|Bacteria,2J0M6@203682|Planctomycetes	203682|Planctomycetes	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
WH3_k127_2797658_0	634498.mru_1246	6.758e-10	72.0	COG1305@1|root,arCOG02555@1|root,arCOG07611@1|root,arCOG02486@2157|Archaea,arCOG02555@2157|Archaea,arCOG07611@2157|Archaea,2XVRZ@28890|Euryarchaeota	2157|Archaea	E	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Chlam_PMP,DUF11
WH3_k127_2800937_3	265072.Mfla_1648	3.048e-13	77.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VP8B@28216|Betaproteobacteria,2KM89@206350|Nitrosomonadales	206350|Nitrosomonadales	EH	Anthranilate synthase component I	-	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
WH3_k127_2800937_1	292459.STH565	1.532e-54	199.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
WH3_k127_2800937_2	1142394.PSMK_11820	1.235e-51	190.0	COG2019@1|root,COG2019@2|Bacteria	2|Bacteria	F	adenylate kinase activity	-	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AAA_17
WH3_k127_2859685_2	880526.KE386488_gene1366	0.0007284	46.0	COG0709@1|root,COG0709@2|Bacteria,4NI4R@976|Bacteroidetes,2FRGC@200643|Bacteroidia	976|Bacteroidetes	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
WH3_k127_2859685_0	1027273.GZ77_25535	1.762e-113	377.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1XHI9@135619|Oceanospirillales	1236|Gammaproteobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	csd	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WH3_k127_2859685_1	880526.KE386488_gene1363	1.183e-33	138.0	COG0425@1|root,COG0425@2|Bacteria,4NS4C@976|Bacteroidetes,2FT3Y@200643|Bacteroidia	976|Bacteroidetes	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,TusA
WH3_k127_2892558_0	517418.Ctha_2620	2.257e-84	297.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WH3_k127_2892558_1	443143.GM18_3649	3.532e-25	109.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2WRJJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
WH3_k127_2892558_2	1112216.JH594425_gene3455	7.817e-20	101.0	COG4191@1|root,COG4191@2|Bacteria,1NVWZ@1224|Proteobacteria,2VCHF@28211|Alphaproteobacteria,2K2C8@204457|Sphingomonadales	204457|Sphingomonadales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c
WH3_k127_2933834_1	706587.Desti_0293	3.113e-16	85.0	COG1633@1|root,COG1633@2|Bacteria,1N4PW@1224|Proteobacteria,42UZG@68525|delta/epsilon subdivisions,2WNGQ@28221|Deltaproteobacteria,2MS9U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
WH3_k127_2933834_0	247490.KSU1_C0416	2.961e-166	537.0	COG0749@1|root,COG0749@2|Bacteria,2IXQR@203682|Planctomycetes	203682|Planctomycetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WH3_k127_2938533_1	264732.Moth_1653	2.986e-36	143.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,42GCN@68295|Thermoanaerobacterales	186801|Clostridia	K	TIGRFAM transcriptional regulator, Rrf2 family	cymR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
WH3_k127_2938533_0	645991.Sgly_2733	5.443e-122	398.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,260EI@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WH3_k127_2957372_4	247490.KSU1_C1680	3.183e-39	151.0	COG0764@1|root,COG0764@2|Bacteria,2IZNA@203682|Planctomycetes	203682|Planctomycetes	I	3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein)	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
WH3_k127_2957372_5	457398.HMPREF0326_00022	2.381e-08	66.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria,2M8DE@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
WH3_k127_2957372_3	313628.LNTAR_14082	1.117e-40	156.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	5.3.4.1	ko:K01829	-	-	-	-	ko00000,ko01000	-	-	-	Thioredoxin_7
WH3_k127_2957372_1	886293.Sinac_0515	6.495e-81	289.0	COG0568@1|root,COG0568@2|Bacteria,2IY72@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03086,ko:K03093	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
WH3_k127_2957372_2	697281.Mahau_1084	2.095e-71	246.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
WH3_k127_2957372_0	589865.DaAHT2_0196	3.599e-129	421.0	COG2025@1|root,COG2086@1|root,COG2025@2|Bacteria,COG2086@2|Bacteria,1MUFI@1224|Proteobacteria,42M3T@68525|delta/epsilon subdivisions,2WIV8@28221|Deltaproteobacteria,2MIMG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein, alpha subunit	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
WH3_k127_295798_0	552811.Dehly_1312	7.906e-181	577.0	COG0542@1|root,COG0542@2|Bacteria,2G62D@200795|Chloroflexi,34CVH@301297|Dehalococcoidia	2|Bacteria	O	Belongs to the ClpA ClpB family	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WH3_k127_2958059_0	1304880.JAGB01000002_gene1618	7.649e-129	425.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia	186801|Clostridia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
WH3_k127_2958059_1	563192.HMPREF0179_03509	1.216e-06	50.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2MBU6@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
WH3_k127_2970048_1	96561.Dole_2075	8.685e-18	85.0	COG0781@1|root,COG0781@2|Bacteria,1N94P@1224|Proteobacteria,42SEA@68525|delta/epsilon subdivisions,2WQP9@28221|Deltaproteobacteria,2MK59@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
WH3_k127_2970048_0	530564.Psta_0392	3.211e-85	290.0	COG1192@1|root,COG1192@2|Bacteria,2IX5Z@203682|Planctomycetes	203682|Planctomycetes	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
WH3_k127_2976503_2	203124.Tery_4615	9.694e-06	57.0	COG0438@1|root,COG0438@2|Bacteria,1G0YI@1117|Cyanobacteria,1H9F1@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	rfaG	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WH3_k127_2976503_0	316067.Geob_3049	4.021e-170	541.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,43TEM@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WH3_k127_2976503_1	338963.Pcar_0051	2.586e-104	345.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2WJBU@28221|Deltaproteobacteria,43U7A@69541|Desulfuromonadales	28221|Deltaproteobacteria	CO	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	nifU	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
WH3_k127_2996589_1	697284.ERIC2_c06590	4.32e-23	104.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,4H9WM@91061|Bacilli,26SPY@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
WH3_k127_2996589_0	269800.Tfu_2024	1.078e-225	710.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4EH1A@85012|Streptosporangiales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WH3_k127_3048496_0	760192.Halhy_4332	8.883e-83	291.0	COG1262@1|root,COG1672@1|root,COG3064@1|root,COG1262@2|Bacteria,COG1672@2|Bacteria,COG3064@2|Bacteria,4PN7M@976|Bacteroidetes,1IXXU@117747|Sphingobacteriia	976|Bacteroidetes	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3059184_0	1353529.M899_0159	1.518e-75	267.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,42Z5J@68525|delta/epsilon subdivisions,2X7Z6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
WH3_k127_3074155_0	2850.Phatr47966	3.694e-73	264.0	2CNWF@1|root,2QYCA@2759|Eukaryota,2XFZH@2836|Bacillariophyta	2836|Bacillariophyta	S	Glycosyltransferase WbsX	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_99
WH3_k127_3074155_1	411468.CLOSCI_03394	2.439e-05	47.0	COG0745@1|root,COG0745@2|Bacteria,1U4FM@1239|Firmicutes,24DF2@186801|Clostridia,222TV@1506553|Lachnoclostridium	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K18344	ko01502,ko02020,map01502,map02020	M00651,M00656	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
WH3_k127_3088702_0	240016.ABIZ01000001_gene2053	4.744e-202	634.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
WH3_k127_3088702_1	207559.Dde_2217	1.824e-12	73.0	COG1309@1|root,COG1309@2|Bacteria,1NP72@1224|Proteobacteria,42T8H@68525|delta/epsilon subdivisions,2WPNA@28221|Deltaproteobacteria,2MASD@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
WH3_k127_3132258_4	2340.JV46_06680	1.323e-06	57.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1J5PH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
WH3_k127_3132258_0	1341151.ASZU01000001_gene683	2.745e-166	539.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli,27B3H@186824|Thermoactinomycetaceae	91061|Bacilli	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
WH3_k127_3132258_1	1120942.AUBM01000010_gene1308	4.584e-157	512.0	COG1063@1|root,COG1063@2|Bacteria,2H3Y2@201174|Actinobacteria,4D42Y@85005|Actinomycetales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	ko:K19956	ko00051,map00051	-	R03234	RC00089	ko00000,ko00001,ko01000	-	-	-	ADH_N
WH3_k127_3132258_2	1035308.AQYY01000001_gene1730	2.249e-102	344.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1USCB@1239|Firmicutes,24FET@186801|Clostridia	186801|Clostridia	IQ	PFAM Short-chain dehydrogenase reductase SDR	srlD	-	1.1.1.140	ko:K00068	ko00051,map00051	-	R05607	RC00085	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
WH3_k127_3132258_3	1168034.FH5T_00995	2.317e-12	70.0	COG0613@1|root,COG0613@2|Bacteria,4NGUQ@976|Bacteroidetes,2FR3M@200643|Bacteroidia	976|Bacteroidetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
WH3_k127_3136943_0	926549.KI421517_gene999	5.006e-230	724.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,47MKQ@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM competence protein ComEA helix-hairpin-helix repeat region	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
WH3_k127_3152582_0	234267.Acid_5704	9.156e-153	492.0	COG0119@1|root,COG0119@2|Bacteria,3Y2WT@57723|Acidobacteria	2|Bacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS10690,iYO844.BSU28280	HMGL-like,LeuA_dimer
WH3_k127_3152582_1	1499967.BAYZ01000041_gene2377	4.283e-08	54.0	COG0551@1|root,COG0551@2|Bacteria,2NQZQ@2323|unclassified Bacteria	2|Bacteria	L	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WH3_k127_3186677_0	665571.STHERM_c07830	3.227e-142	459.0	COG2021@1|root,COG2021@2|Bacteria,2JA6P@203691|Spirochaetes	203691|Spirochaetes	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
WH3_k127_3195239_0	316067.Geob_3374	2.397e-46	179.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,43TCZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
WH3_k127_3195239_3	40373.F991_03150	1.011e-07	60.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,1RRN7@1236|Gammaproteobacteria,3NJ8W@468|Moraxellaceae	1236|Gammaproteobacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
WH3_k127_3195239_2	314230.DSM3645_24260	2.447e-19	99.0	COG4972@1|root,COG4972@2|Bacteria,2IZC6@203682|Planctomycetes	203682|Planctomycetes	NU	pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
WH3_k127_3218066_0	240016.ABIZ01000001_gene5154	4.996e-48	188.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WH3_k127_3229076_0	1500890.JQNL01000001_gene3784	7.634e-35	136.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1X5QC@135614|Xanthomonadales	135614|Xanthomonadales	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WH3_k127_3229076_1	530564.Psta_2876	2.558e-06	56.0	2C65R@1|root,3318E@2|Bacteria,2J0VS@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3229076_2	1497679.EP56_04395	0.000132	48.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,26IUM@186820|Listeriaceae	91061|Bacilli	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WH3_k127_3238936_2	1205908.AKXW01000066_gene2909	0.0003012	51.0	2BZ7H@1|root,34C4G@2|Bacteria,1P3BN@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3238936_0	1396418.BATQ01000041_gene6309	3.791e-112	381.0	COG0443@1|root,COG0443@2|Bacteria,46SDM@74201|Verrucomicrobia,2ITH0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	MreB/Mbl protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
WH3_k127_3238936_1	1205908.AKXW01000066_gene2907	6.686e-07	61.0	COG3793@1|root,COG3793@2|Bacteria,1NS76@1224|Proteobacteria	1224|Proteobacteria	P	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
WH3_k127_3243848_0	794903.OPIT5_10335	6.174e-42	170.0	COG1449@1|root,COG1449@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
WH3_k127_3243848_1	1077285.AGDG01000028_gene1483	1.012e-21	99.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,2FNXT@200643|Bacteroidia,4AKGI@815|Bacteroidaceae	976|Bacteroidetes	S	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
WH3_k127_3244330_0	177437.HRM2_43980	1.354e-55	212.0	COG0840@1|root,COG0840@2|Bacteria,1N12X@1224|Proteobacteria,42UQY@68525|delta/epsilon subdivisions,2WPZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	transmembrane signaling receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3278976_0	926549.KI421517_gene1530	4.211e-159	513.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,47JNX@768503|Cytophagia	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WH3_k127_3278976_1	1123277.KB893201_gene6436	1.169e-29	124.0	COG1082@1|root,COG1082@2|Bacteria,4NJJZ@976|Bacteroidetes,47PI6@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
WH3_k127_3285407_1	575540.Isop_1066	1.24e-44	179.0	COG1197@1|root,COG1197@2|Bacteria,2IWV4@203682|Planctomycetes	203682|Planctomycetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WH3_k127_3285407_0	635013.TherJR_2349	3.755e-131	428.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,2607Y@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA2	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
WH3_k127_3316154_0	1009370.ALO_21309	7.75e-213	681.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H2CW@909932|Negativicutes	909932|Negativicutes	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WH3_k127_33332_0	573413.Spirs_2327	1.82e-164	530.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2J5WW@203691|Spirochaetes	203691|Spirochaetes	E	PFAM Conserved region in glutamate synthase	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4,GATase_2,GXGXG,Glu_syn_central,Glu_synthase
WH3_k127_33332_1	203119.Cthe_0863	1.148e-44	168.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae	186801|Clostridia	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
WH3_k127_3350037_1	348780.NP_0138A	1.632e-12	77.0	COG0642@1|root,COG0784@1|root,arCOG02589@2157|Archaea,arCOG06408@2157|Archaea,2XWXH@28890|Euryarchaeota,23VAM@183963|Halobacteria	183963|Halobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_4
WH3_k127_3350037_0	1157640.AQWO01000008_gene3931	4.109e-15	87.0	COG0815@1|root,COG0815@2|Bacteria,2GP8X@201174|Actinobacteria	201174|Actinobacteria	M	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
WH3_k127_3367108_2	498848.TaqDRAFT_4855	1.364e-35	146.0	COG0801@1|root,COG0801@2|Bacteria,1WJU9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
WH3_k127_3367108_0	1304880.JAGB01000002_gene1967	3.024e-188	595.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia	186801|Clostridia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WH3_k127_3367108_1	314230.DSM3645_06214	1.342e-82	282.0	COG0047@1|root,COG0047@2|Bacteria,2IYT2@203682|Planctomycetes	203682|Planctomycetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
WH3_k127_3367108_3	247490.KSU1_D0830	3.868e-33	133.0	COG0046@1|root,COG0046@2|Bacteria,2IXRT@203682|Planctomycetes	203682|Planctomycetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
WH3_k127_3388148_1	1123508.JH636442_gene4047	2.25e-31	131.0	COG0750@1|root,COG0750@2|Bacteria,2IXWE@203682|Planctomycetes	203682|Planctomycetes	M	PDZ domain (Also known as DHR	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
WH3_k127_3388148_0	1128398.Curi_c15650	9.15e-50	182.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,267TD@186813|unclassified Clostridiales	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
WH3_k127_3422528_2	246197.MXAN_6487	9.884e-06	51.0	COG1538@1|root,COG1538@2|Bacteria,1R8XP@1224|Proteobacteria,42QM9@68525|delta/epsilon subdivisions,2WKY8@28221|Deltaproteobacteria,2YX1I@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP
WH3_k127_3422528_1	1304885.AUEY01000040_gene1619	1.069e-38	159.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,43AY8@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K02005,ko:K03585,ko:K18306	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,2.A.6.2.20,2.A.6.2.32,8.A.1,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WH3_k127_3422528_0	760568.Desku_0101	8.878e-187	606.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,260X3@186807|Peptococcaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
WH3_k127_3462831_0	483216.BACEGG_03296	5.618e-176	580.0	COG3250@1|root,COG3250@2|Bacteria,4NGNR@976|Bacteroidetes,2FQ2C@200643|Bacteroidia,4ANIJ@815|Bacteroidaceae	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C
WH3_k127_3462831_1	471870.BACINT_01445	9.721e-07	60.0	COG3250@1|root,COG3250@2|Bacteria,4NGNR@976|Bacteroidetes,2FQ2C@200643|Bacteroidia,4ANIJ@815|Bacteroidaceae	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C
WH3_k127_3468383_0	316067.Geob_2951	5.384e-126	415.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ00@28221|Deltaproteobacteria,43UQW@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
WH3_k127_3468383_1	290397.Adeh_2788	1.513e-26	111.0	COG0171@1|root,COG0171@2|Bacteria,1QHZ4@1224|Proteobacteria,42QD8@68525|delta/epsilon subdivisions,2WMK9@28221|Deltaproteobacteria,2YZFC@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
WH3_k127_3485579_0	338963.Pcar_3090	6.404e-68	241.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,42P0U@68525|delta/epsilon subdivisions,2WJC6@28221|Deltaproteobacteria,43T6F@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WH3_k127_3485579_1	1159488.SEQMU2_03820	4.281e-26	113.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,4GXRG@90964|Staphylococcaceae	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
WH3_k127_3495906_0	882.DVU_0857	5.426e-108	361.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42N9E@68525|delta/epsilon subdivisions,2WJAX@28221|Deltaproteobacteria,2M7YX@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
WH3_k127_3504389_0	610130.Closa_3517	2.828e-52	202.0	COG3210@1|root,COG4932@1|root,COG5263@1|root,COG3210@2|Bacteria,COG4932@2|Bacteria,COG5263@2|Bacteria,1UYJ9@1239|Firmicutes,248QE@186801|Clostridia,21ZR1@1506553|Lachnoclostridium	186801|Clostridia	N	cell wall binding repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CW_binding_1,Glug,LRR_5,LysM,SLH
WH3_k127_3513162_0	555079.Toce_2041	1.595e-206	649.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,42FIF@68295|Thermoanaerobacterales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
WH3_k127_3513162_1	525903.Taci_0858	3.441e-69	242.0	COG1155@1|root,COG1155@2|Bacteria,3TA3Y@508458|Synergistetes	508458|Synergistetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	atpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
WH3_k127_3514894_2	1461579.CCNK01000045_gene2224	4.045e-17	84.0	COG0512@1|root,COG0512@2|Bacteria,1RAKJ@1224|Proteobacteria,1RREB@1236|Gammaproteobacteria,1Y7E2@135625|Pasteurellales	135625|Pasteurellales	EH	Anthranilate synthase	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
WH3_k127_3514894_0	1236542.BALM01000004_gene2413	2.029e-100	347.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,2QAQ1@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Anthranilate synthase component I domain protein	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657,ko:K13503	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iG2583_1286.G2583_1603	Anth_synt_I_N,Chorismate_bind
WH3_k127_3514894_1	1120950.KB892765_gene5700	5.496e-29	121.0	COG1525@1|root,COG1525@2|Bacteria,2GRK1@201174|Actinobacteria,4DVX3@85009|Propionibacteriales	201174|Actinobacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174,ko:K07038	-	-	-	-	ko00000,ko01000	-	-	-	SNase
WH3_k127_351492_1	1307759.JOMJ01000004_gene3048	1.869e-35	139.0	COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,43AKX@68525|delta/epsilon subdivisions,2X612@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WH3_k127_351492_0	865861.AZSU01000003_gene2027	1.689e-45	174.0	COG3267@1|root,COG3267@2|Bacteria,1TRGM@1239|Firmicutes,24EPV@186801|Clostridia,36HUB@31979|Clostridiaceae	186801|Clostridia	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
WH3_k127_354272_0	595460.RRSWK_06558	7.144e-92	310.0	COG2755@1|root,COG2755@2|Bacteria,2IYGD@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
WH3_k127_3543564_0	1157490.EL26_07315	9.836e-06	57.0	COG4085@1|root,COG5337@1|root,COG4085@2|Bacteria,COG5337@2|Bacteria,1TSI3@1239|Firmicutes,4HAWG@91061|Bacilli	91061|Bacilli	N	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
WH3_k127_3547186_0	247490.KSU1_D0789	2.219e-76	271.0	COG0771@1|root,COG0771@2|Bacteria,2IX53@203682|Planctomycetes	203682|Planctomycetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WH3_k127_3547186_1	530564.Psta_1002	2.55e-34	137.0	COG0284@1|root,COG0284@2|Bacteria,2IXSF@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
WH3_k127_3548163_0	926561.KB900621_gene2825	4.819e-152	496.0	COG0415@1|root,COG0415@2|Bacteria,1UDZT@1239|Firmicutes,249FJ@186801|Clostridia,3WAHJ@53433|Halanaerobiales	186801|Clostridia	L	PFAM DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase
WH3_k127_3548163_1	927658.AJUM01000034_gene575	6.748e-137	450.0	COG0534@1|root,COG0534@2|Bacteria	2|Bacteria	V	drug transmembrane transporter activity	norM-2	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
WH3_k127_3548163_3	220341.16504802	2.012e-21	107.0	2DBFB@1|root,2Z8XA@2|Bacteria,1MVTN@1224|Proteobacteria,1RM97@1236|Gammaproteobacteria,3ZJPZ@590|Salmonella	1236|Gammaproteobacteria	S	Protein of unknown function (DUF4056)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4056
WH3_k127_3548163_2	158189.SpiBuddy_1061	3.816e-46	168.0	COG0667@1|root,COG0667@2|Bacteria,2J6C3@203691|Spirochaetes	203691|Spirochaetes	C	PFAM Aldo keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
WH3_k127_3556771_0	1123401.JHYQ01000014_gene803	1.717e-146	476.0	COG1672@1|root,COG1672@2|Bacteria,1MWJX@1224|Proteobacteria,1RWRA@1236|Gammaproteobacteria,461SW@72273|Thiotrichales	72273|Thiotrichales	S	Archaea bacterial proteins of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_2,DUF234
WH3_k127_3556771_2	1173027.Mic7113_4247	6.961e-83	282.0	COG1028@1|root,COG1028@2|Bacteria,1G40X@1117|Cyanobacteria,1H962@1150|Oscillatoriales	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH3_k127_3556771_1	926550.CLDAP_22570	4.617e-98	328.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi	200795|Chloroflexi	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
WH3_k127_355793_0	398767.Glov_0806	3.664e-71	249.0	COG4191@1|root,COG4251@1|root,COG4191@2|Bacteria,COG4251@2|Bacteria,1RCM9@1224|Proteobacteria,43CGJ@68525|delta/epsilon subdivisions,2X7RR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
WH3_k127_355793_1	716544.wcw_0946	2.673e-10	68.0	COG1266@1|root,COG1266@2|Bacteria,2JGC1@204428|Chlamydiae	204428|Chlamydiae	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WH3_k127_355793_2	1121440.AUMA01000005_gene2693	3.857e-10	62.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,42NIG@68525|delta/epsilon subdivisions,2WIR1@28221|Deltaproteobacteria,2M8X6@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
WH3_k127_3560016_0	452637.Oter_3758	1.617e-29	133.0	COG1477@1|root,COG1477@2|Bacteria,46W8K@74201|Verrucomicrobia,3K9TT@414999|Opitutae	414999|Opitutae	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
WH3_k127_3560016_1	240016.ABIZ01000001_gene2631	2.176e-17	95.0	COG4745@1|root,COG4745@2|Bacteria,46T45@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WH3_k127_3581956_2	768706.Desor_3721	4.6e-74	250.0	COG0432@1|root,COG0432@2|Bacteria,1V201@1239|Firmicutes,24FTY@186801|Clostridia,261SP@186807|Peptococcaceae	186801|Clostridia	J	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
WH3_k127_3581956_0	1232410.KI421416_gene2699	4.683e-191	615.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2WJJP@28221|Deltaproteobacteria,43UUZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sulfate permease family	ychM	-	4.2.1.1	ko:K01673,ko:K03321	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000,ko02000	2.A.53.3	-	-	Pro_CA,STAS,STAS_2,Sulfate_transp
WH3_k127_3581956_1	1121440.AUMA01000016_gene193	7.599e-81	274.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,43ADI@68525|delta/epsilon subdivisions,2WPU6@28221|Deltaproteobacteria,2MB6H@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Reversible hydration of carbon dioxide	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
WH3_k127_3581956_3	693661.Arcve_1058	4.359e-35	141.0	COG1280@1|root,arCOG01947@2157|Archaea,2XXV9@28890|Euryarchaeota,246CA@183980|Archaeoglobi	183980|Archaeoglobi	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
WH3_k127_3581956_4	96561.Dole_2595	1.544e-26	109.0	2E32K@1|root,32Y2U@2|Bacteria,1N8SE@1224|Proteobacteria,42WC1@68525|delta/epsilon subdivisions,2WS7P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3590998_0	344747.PM8797T_18194	4.941e-133	432.0	COG0480@1|root,COG0480@2|Bacteria,2IXUD@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WH3_k127_3590998_3	706587.Desti_4611	1.247e-24	108.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MS96@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
WH3_k127_3590998_1	1142394.PSMK_03510	1.63e-42	163.0	COG1595@1|root,COG1595@2|Bacteria,2IZ91@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH3_k127_3590998_2	1123237.Salmuc_00701	2.863e-42	160.0	arCOG05193@1|root,2ZZSG@2|Bacteria,1REJB@1224|Proteobacteria,2U7D9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3601305_0	439235.Dalk_3544	1.963e-08	67.0	29RQM@1|root,30CU4@2|Bacteria,1NU3F@1224|Proteobacteria,42YUA@68525|delta/epsilon subdivisions,2WUNP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3652312_2	1158762.KB898037_gene2247	4.909e-07	56.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1WW01@135613|Chromatiales	135613|Chromatiales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
WH3_k127_3652312_0	555088.DealDRAFT_2075	4.156e-68	239.0	arCOG03165@1|root,30AIC@2|Bacteria,1V7NB@1239|Firmicutes,24M5X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3652312_1	42256.RradSPS_1830	4.732e-42	159.0	COG0667@1|root,COG0667@2|Bacteria,2H2ID@201174|Actinobacteria,4CR5G@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WH3_k127_3674326_0	1142394.PSMK_14030	4.134e-110	389.0	COG1450@1|root,COG1450@2|Bacteria,2IX4B@203682|Planctomycetes	203682|Planctomycetes	NU	general secretion pathway protein D	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
WH3_k127_3683949_1	929558.SMGD1_2496	2.703e-33	132.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2YN0Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
WH3_k127_3683949_0	237368.SCABRO_02293	7.042e-45	179.0	COG0457@1|root,COG0457@2|Bacteria,2IZWD@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8,Transglut_core2
WH3_k127_3726288_1	1009370.ALO_08263	3.832e-18	87.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,4H2FZ@909932|Negativicutes	909932|Negativicutes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
WH3_k127_3726288_0	497964.CfE428DRAFT_4452	2.696e-123	411.0	COG1696@1|root,COG1696@2|Bacteria,46TUI@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM membrane bound O-acyl transferase MBOAT family protein	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
WH3_k127_3729861_2	485917.Phep_3012	2.981e-25	108.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1IPBQ@117747|Sphingobacteriia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
WH3_k127_3729861_3	1123508.JH636439_gene571	1.811e-24	117.0	COG4591@1|root,COG4591@2|Bacteria,2IY15@203682|Planctomycetes	203682|Planctomycetes	M	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
WH3_k127_3729861_4	856793.MICA_1343	1.054e-18	99.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2TRBX@28211|Alphaproteobacteria,4BPKM@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
WH3_k127_3729861_0	575540.Isop_2677	5.181e-173	555.0	COG1190@1|root,COG1190@2|Bacteria,2IXHX@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WH3_k127_3729861_1	237368.SCABRO_00555	1.128e-40	160.0	COG0793@1|root,COG0793@2|Bacteria,2IX9Q@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
WH3_k127_3752283_0	562970.Btus_0496	1.571e-96	321.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,278X3@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
WH3_k127_3752283_1	237368.SCABRO_01259	9.737e-65	250.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2IY17@203682|Planctomycetes	203682|Planctomycetes	S	competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
WH3_k127_3752283_2	237368.SCABRO_03873	1.18e-23	109.0	COG1360@1|root,COG1360@2|Bacteria,2IZSF@203682|Planctomycetes	203682|Planctomycetes	N	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
WH3_k127_3752283_3	1142394.PSMK_18480	1.093e-17	85.0	COG1989@1|root,COG1989@2|Bacteria,2IZQ8@203682|Planctomycetes	203682|Planctomycetes	NOU	Bacterial Peptidase A24 N-terminal domain	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
WH3_k127_3795025_3	1384065.JAGS01000001_gene3002	5.246e-13	72.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,24QXB@186801|Clostridia,3WKMB@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
WH3_k127_3795025_0	379066.GAU_0558	1.95e-176	572.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1ZT6C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
WH3_k127_3795025_2	1120968.AUBX01000009_gene615	2.482e-45	168.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,47R3N@768503|Cytophagia	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
WH3_k127_3795025_1	616991.JPOO01000001_gene3961	2.846e-147	481.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,1HX8I@117743|Flavobacteriia,23GUS@178469|Arenibacter	976|Bacteroidetes	P	C-terminal region of aryl-sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
WH3_k127_3798740_0	1499967.BAYZ01000001_gene5910	3.326e-48	181.0	COG0525@1|root,COG0525@2|Bacteria,2NNKR@2323|unclassified Bacteria	2|Bacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WH3_k127_3798740_1	583355.Caka_0545	1.153e-44	169.0	COG0673@1|root,COG0673@2|Bacteria,46UTE@74201|Verrucomicrobia,3K8EQ@414999|Opitutae	414999|Opitutae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.99.28	ko:K00118	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WH3_k127_3808419_0	1492737.FEM08_26710	1.108e-92	314.0	COG3654@1|root,COG3943@1|root,COG3654@2|Bacteria,COG3943@2|Bacteria,4NEGN@976|Bacteroidetes,1HYIM@117743|Flavobacteriia,2NV0H@237|Flavobacterium	976|Bacteroidetes	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
WH3_k127_3808419_1	1142394.PSMK_31720	5.498e-44	175.0	COG0705@1|root,COG0705@2|Bacteria,2IZZY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WH3_k127_3809497_1	123214.PERMA_1989	2.233e-10	61.0	COG0529@1|root,COG0529@2|Bacteria,2G3Q7@200783|Aquificae	200783|Aquificae	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
WH3_k127_3809497_0	1125863.JAFN01000001_gene943	4.622e-161	510.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,42NYE@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	PFAM Phosphoadenosine phosphosulfate reductase	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
WH3_k127_3816223_0	1396141.BATP01000059_gene2432	2.623e-19	96.0	COG1595@1|root,COG1595@2|Bacteria,46XM2@74201|Verrucomicrobia,2IW65@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
WH3_k127_3822164_3	247490.KSU1_C1592	7.928e-76	271.0	COG0373@1|root,COG0373@2|Bacteria,2IXE9@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
WH3_k127_3822164_1	247490.KSU1_C1279	8.082e-106	355.0	COG0535@1|root,COG0535@2|Bacteria,2IZE3@203682|Planctomycetes	203682|Planctomycetes	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
WH3_k127_3822164_0	1123242.JH636434_gene3230	2.875e-154	497.0	COG0001@1|root,COG0001@2|Bacteria,2IX4X@203682|Planctomycetes	203682|Planctomycetes	H	COG0001 Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WH3_k127_3822164_2	795359.TOPB45_1456	4.998e-103	351.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GH4Q@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
WH3_k127_3822164_4	1121428.DESHY_10156___1	1.059e-33	136.0	COG1522@1|root,COG1522@2|Bacteria,1V6TK@1239|Firmicutes,24KE6@186801|Clostridia,2627S@186807|Peptococcaceae	186801|Clostridia	K	SMART Transcription regulator, AsnC-type	nirD	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
WH3_k127_3822164_5	1469557.JSWF01000017_gene2282	1.504e-12	68.0	COG5309@1|root,COG5309@2|Bacteria,4NFD7@976|Bacteroidetes,1HY34@117743|Flavobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 17	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_17
WH3_k127_3825184_0	1142394.PSMK_24160	9.229e-83	296.0	COG1674@1|root,COG1674@2|Bacteria,2IXHF@203682|Planctomycetes	203682|Planctomycetes	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WH3_k127_3827035_0	509191.AEDB02000021_gene3128	3.316e-182	580.0	COG2115@1|root,COG2115@2|Bacteria,1TQW2@1239|Firmicutes,24869@186801|Clostridia,3WGPC@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the xylose isomerase family	xylA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08960	AP_endonuc_2
WH3_k127_3827035_2	1499967.BAYZ01000151_gene1675	1.275e-51	194.0	COG1355@1|root,COG1355@2|Bacteria,2NQ00@2323|unclassified Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
WH3_k127_3827035_3	1121403.AUCV01000002_gene609	8.268e-46	170.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2MIPF@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
WH3_k127_3827035_1	243231.GSU0913	1.404e-134	439.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,43T4P@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC transporter C-terminal domain	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WH3_k127_3839521_0	696369.KI912183_gene2497	9.892e-162	519.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,2617C@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
WH3_k127_3868014_1	1249480.B649_05550	6.208e-31	129.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42PQZ@68525|delta/epsilon subdivisions,2YNEV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind,Laminin_G_3
WH3_k127_3868014_0	1122176.KB903531_gene2762	1.944e-45	176.0	COG1572@1|root,COG4447@1|root,COG1572@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Laminin_G_3,TM_helix
WH3_k127_3881652_1	237368.SCABRO_01907	4.397e-36	141.0	COG0629@1|root,COG0629@2|Bacteria,2IZJ8@203682|Planctomycetes	203682|Planctomycetes	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WH3_k127_3881652_3	247490.KSU1_B0547	3.392e-16	84.0	COG0360@1|root,COG0360@2|Bacteria,2J0U0@203682|Planctomycetes	203682|Planctomycetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
WH3_k127_3881652_0	1031288.AXAA01000027_gene1804	1.867e-50	186.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,36G0N@31979|Clostridiaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
WH3_k127_3881652_2	530564.Psta_2671	4.26e-20	94.0	COG1825@1|root,COG1825@2|Bacteria,2J050@203682|Planctomycetes	203682|Planctomycetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
WH3_k127_389385_2	595460.RRSWK_03351	3.074e-07	56.0	COG5471@1|root,COG5471@2|Bacteria,2J1PT@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (DUF2190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2190
WH3_k127_389385_1	575540.Isop_2432	1.99e-09	63.0	2ETQX@1|root,33M8I@2|Bacteria,2J1E8@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3897634_0	536233.CLO_0798	1.036e-10	71.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,36DUH@31979|Clostridiaceae	186801|Clostridia	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
WH3_k127_3904181_0	886293.Sinac_1881	2.915e-43	176.0	COG0681@1|root,COG0681@2|Bacteria,2IYWI@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
WH3_k127_3904181_1	1123242.JH636434_gene5428	3.695e-12	70.0	COG0681@1|root,COG0681@2|Bacteria,2IY6X@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
WH3_k127_3909364_0	644966.Tmar_1796	5.16e-105	346.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WCUJ@538999|Clostridiales incertae sedis	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WH3_k127_3909364_2	1229203.KI301992_gene1724	4.005e-08	59.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
WH3_k127_3909364_1	1209989.TepiRe1_0788	4.639e-11	70.0	COG4747@1|root,COG4747@2|Bacteria,1V7U2@1239|Firmicutes,24JE5@186801|Clostridia,42GI5@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
WH3_k127_3942972_0	665956.HMPREF1032_00848	1.473e-65	232.0	COG0407@1|root,COG0407@2|Bacteria,1UY51@1239|Firmicutes,24E75@186801|Clostridia,3WPCX@541000|Ruminococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
WH3_k127_3942972_1	1123508.JH636444_gene5246	5.248e-32	133.0	COG0815@1|root,COG0815@2|Bacteria,2IWUW@203682|Planctomycetes	203682|Planctomycetes	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
WH3_k127_3950104_0	1396141.BATP01000056_gene3201	2.127e-141	473.0	COG1404@1|root,COG3210@1|root,COG4412@1|root,COG5492@1|root,COG1404@2|Bacteria,COG3210@2|Bacteria,COG4412@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Peptidase_S8,fn3
WH3_k127_3955316_0	1168034.FH5T_01580	6.812e-59	211.0	COG1520@1|root,COG1520@2|Bacteria,4P0ZC@976|Bacteroidetes,2FW9F@200643|Bacteroidia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
WH3_k127_3955316_3	1303518.CCALI_01840	1.792e-09	68.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
WH3_k127_3955316_4	1038867.AXAY01000035_gene4457	1.525e-07	54.0	2DSQC@1|root,33H1C@2|Bacteria,1NCJN@1224|Proteobacteria,2UJSK@28211|Alphaproteobacteria,3K24C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3955316_2	1499686.BN1079_00794	1.885e-37	144.0	292H0@1|root,2ZQ15@2|Bacteria,1RETR@1224|Proteobacteria,1STXT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3965247_1	927677.ALVU02000001_gene2257	1.832e-08	56.0	COG0286@1|root,COG0286@2|Bacteria,1G119@1117|Cyanobacteria	1117|Cyanobacteria	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
WH3_k127_3965247_0	945713.IALB_2433	2.81e-104	350.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	DUF3318,Peptidase_M48
WH3_k127_3971180_0	909663.KI867150_gene300	1.289e-248	784.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,2MR4V@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
WH3_k127_3971180_2	439235.Dalk_1640	8.713e-08	57.0	COG0735@1|root,COG1918@1|root,COG0735@2|Bacteria,COG1918@2|Bacteria,1RDWJ@1224|Proteobacteria,42P61@68525|delta/epsilon subdivisions,2X5PQ@28221|Deltaproteobacteria,2MJ7H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR,FeoA
WH3_k127_3971180_1	644282.Deba_1956	4.317e-26	111.0	COG1321@1|root,COG1321@2|Bacteria,1RHIK@1224|Proteobacteria,42SAD@68525|delta/epsilon subdivisions,2WPIC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Iron (Metal) dependent repressor, DtxR family	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
WH3_k127_4010215_0	1121430.JMLG01000001_gene2198	9.281e-90	305.0	COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,249JV@186801|Clostridia,26034@186807|Peptococcaceae	186801|Clostridia	C	Radical SAM	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,LAM_C,Radical_SAM
WH3_k127_4021587_2	383372.Rcas_3098	1.167e-07	63.0	COG0438@1|root,COG0438@2|Bacteria,2GBA1@200795|Chloroflexi,377MX@32061|Chloroflexia	32061|Chloroflexia	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH3_k127_4021587_0	398512.JQKC01000006_gene688	4.392e-51	195.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WH3_k127_4021587_1	383372.Rcas_0758	3.269e-18	88.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WH3_k127_4038277_1	330214.NIDE3354	8.21e-78	269.0	COG0005@1|root,COG0005@2|Bacteria,3J0HC@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
WH3_k127_4038277_0	1121013.P873_12965	6.54e-89	299.0	COG4760@1|root,COG4760@2|Bacteria,1REUF@1224|Proteobacteria,1T1EH@1236|Gammaproteobacteria,1XD49@135614|Xanthomonadales	135614|Xanthomonadales	S	Inhibitor of apoptosis-promoting Bax1	-	-	-	-	-	-	-	-	-	-	-	-	BaxI_1
WH3_k127_4038277_2	926560.KE387023_gene3509	5.333e-27	116.0	COG0508@1|root,COG0508@2|Bacteria,1WI0W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WH3_k127_4039036_0	247490.KSU1_B0370	3.015e-156	505.0	COG0188@1|root,COG0188@2|Bacteria,2IY0U@203682|Planctomycetes	203682|Planctomycetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WH3_k127_4044832_0	589865.DaAHT2_0197	1.539e-223	705.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,42PTE@68525|delta/epsilon subdivisions,2WKRZ@28221|Deltaproteobacteria,2MIH0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
WH3_k127_4044832_1	589865.DaAHT2_0196	2.677e-151	486.0	COG2025@1|root,COG2086@1|root,COG2025@2|Bacteria,COG2086@2|Bacteria,1MUFI@1224|Proteobacteria,42M3T@68525|delta/epsilon subdivisions,2WIV8@28221|Deltaproteobacteria,2MIMG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein, alpha subunit	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
WH3_k127_41032_2	521674.Plim_3957	1.809e-06	59.0	COG5652@1|root,COG5652@2|Bacteria,2J19Q@203682|Planctomycetes	203682|Planctomycetes	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
WH3_k127_41032_0	794903.OPIT5_24610	1.497e-74	265.0	COG0657@1|root,COG0657@2|Bacteria,46UVS@74201|Verrucomicrobia	2|Bacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
WH3_k127_41032_1	530564.Psta_3244	1.661e-26	123.0	COG3250@1|root,COG3250@2|Bacteria,2J54D@203682|Planctomycetes	203682|Planctomycetes	G	Pfam:DUF303	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
WH3_k127_4108822_0	443143.GM18_0349	4.579e-283	899.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2WIZT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	phospholipid glycerol acyltransferase	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
WH3_k127_4108822_1	403833.Pmob_1753	1.822e-80	284.0	COG2865@1|root,COG3432@1|root,COG2865@2|Bacteria,COG3432@2|Bacteria,2GE55@200918|Thermotogae	200918|Thermotogae	K	Transcriptional regulator	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
WH3_k127_4123980_1	237368.SCABRO_00373	5.13e-55	201.0	COG3481@1|root,COG3481@2|Bacteria,2IX5B@203682|Planctomycetes	203682|Planctomycetes	S	Nucleic acid binding	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
WH3_k127_4123980_3	761193.Runsl_5137	3.038e-05	51.0	2DRCR@1|root,33B8F@2|Bacteria,4NUWN@976|Bacteroidetes,47S80@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4174)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4174
WH3_k127_4123980_0	314230.DSM3645_16135	8.076e-68	235.0	COG0745@1|root,COG0745@2|Bacteria,2IY82@203682|Planctomycetes	203682|Planctomycetes	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Response_reg
WH3_k127_4123980_2	1142394.PSMK_22590	3.205e-28	128.0	COG1639@1|root,COG4191@1|root,COG1639@2|Bacteria,COG4191@2|Bacteria,2J037@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HDOD,HisKA
WH3_k127_4149468_1	290399.Arth_4055	1.101e-12	79.0	COG2244@1|root,COG2244@2|Bacteria,2H55P@201174|Actinobacteria	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	-	-	-	ko:K03328,ko:K16695	-	-	-	-	ko00000,ko02000	2.A.66.2,2.A.66.2.7	-	-	Polysacc_synt_3,Polysacc_synt_C
WH3_k127_4149468_0	1123377.AUIV01000007_gene1256	1.103e-22	104.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1X3SF@135614|Xanthomonadales	135614|Xanthomonadales	U	Type II secretory pathway, component HofQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
WH3_k127_4154801_1	575540.Isop_2435	8.996e-26	110.0	COG5511@1|root,COG5511@2|Bacteria,2IZFA@203682|Planctomycetes	203682|Planctomycetes	S	Phage portal protein, lambda family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal_2
WH3_k127_4154801_0	575540.Isop_2434	2.64e-111	376.0	COG3087@1|root,COG3087@2|Bacteria,2IX3F@203682|Planctomycetes	203682|Planctomycetes	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4166468_0	186497.PF1533	3.157e-06	59.0	COG1030@1|root,arCOG01910@2157|Archaea,2XW1R@28890|Euryarchaeota,242U5@183968|Thermococci	183968|Thermococci	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
WH3_k127_4177256_0	443143.GM18_1745	1.248e-137	446.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
WH3_k127_418583_0	748727.CLJU_c17370	5.504e-163	518.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,36DW6@31979|Clostridiaceae	186801|Clostridia	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
WH3_k127_4216873_0	858215.Thexy_0114	6.251e-51	190.0	COG0068@1|root,COG0068@2|Bacteria,1TQM7@1239|Firmicutes,2494A@186801|Clostridia,42EWS@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
WH3_k127_4231402_0	398767.Glov_0732	1.758e-100	339.0	COG5505@1|root,COG5505@2|Bacteria,1MW87@1224|Proteobacteria,42RQH@68525|delta/epsilon subdivisions,2WTKY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
WH3_k127_4231402_1	909663.KI867150_gene689	1.336e-58	209.0	COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,43BF8@68525|delta/epsilon subdivisions,2X6TM@28221|Deltaproteobacteria,2MSGQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
WH3_k127_4232362_3	247490.KSU1_C0630	3.376e-45	170.0	COG0132@1|root,COG0132@2|Bacteria,2J026@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
WH3_k127_4232362_1	324602.Caur_1459	1.331e-70	245.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	rebM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WH3_k127_4232362_0	1396141.BATP01000039_gene1238	3.481e-168	552.0	COG3250@1|root,COG3250@2|Bacteria,46U8X@74201|Verrucomicrobia,2IWQ5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_N,SASA
WH3_k127_4232362_2	111105.HR09_10325	4.713e-59	216.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,2FPCB@200643|Bacteroidia,22W87@171551|Porphyromonadaceae	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
WH3_k127_4239184_0	1232410.KI421422_gene1955	7.204e-101	341.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,43U7Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WH3_k127_4239184_1	1142394.PSMK_04760	0.0006648	44.0	2FGJC@1|root,348F6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
WH3_k127_4245399_0	720554.Clocl_3417	5.42e-155	499.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1TQXK@1239|Firmicutes,25EK3@186801|Clostridia,3WISI@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D3
WH3_k127_4245399_1	1121324.CLIT_11c02590	4.343e-25	104.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia	186801|Clostridia	EH	PFAM Phosphoadenosine phosphosulfate reductase	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
WH3_k127_4252217_1	207559.Dde_0961	8.668e-14	81.0	COG1538@1|root,COG1538@2|Bacteria,1Q54P@1224|Proteobacteria,42NQV@68525|delta/epsilon subdivisions,2WKMG@28221|Deltaproteobacteria,2M7UB@213115|Desulfovibrionales	28221|Deltaproteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WH3_k127_4252217_0	666685.R2APBS1_1778	2.966e-20	99.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,1S401@1236|Gammaproteobacteria,1X396@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WH3_k127_4298726_0	247490.KSU1_C0154	8.013e-105	351.0	COG0536@1|root,COG0536@2|Bacteria,2IX0Z@203682|Planctomycetes	203682|Planctomycetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
WH3_k127_4298726_1	610130.Closa_2272	2.372e-14	74.0	COG0778@1|root,COG0778@2|Bacteria,1V7RH@1239|Firmicutes,24KRJ@186801|Clostridia,222VT@1506553|Lachnoclostridium	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WH3_k127_4325695_1	521674.Plim_4077	3.964e-30	129.0	COG1360@1|root,COG1360@2|Bacteria	2|Bacteria	N	Flagellar Motor Protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
WH3_k127_4325695_0	671143.DAMO_2134	4.059e-35	137.0	COG0272@1|root,COG0272@2|Bacteria,2NNSW@2323|unclassified Bacteria	2|Bacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	2.7.7.7,6.5.1.2	ko:K01972,ko:K02342,ko:K04096,ko:K12472	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03430,ko03440,ko04144,map00230,map00240,map01100,map03030,map03410,map03420,map03430,map03440,map04144	M00260	R00375,R00376,R00377,R00378,R00382	RC00005,RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400,ko04131	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5,RNase_T
WH3_k127_4325695_2	358681.BBR47_06860	1.184e-18	86.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,26QDH@186822|Paenibacillaceae	91061|Bacilli	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WH3_k127_4331797_2	1396418.BATQ01000104_gene5500	3.103e-29	119.0	COG4112@1|root,COG4112@2|Bacteria,46V3C@74201|Verrucomicrobia,2IU8G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4331797_0	96561.Dole_0311	6.369e-73	256.0	COG1143@1|root,COG2878@1|root,COG1143@2|Bacteria,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,42PTG@68525|delta/epsilon subdivisions,2WKYG@28221|Deltaproteobacteria,2MIM0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM electron transport complex, RnfABCDGE type, B subunit	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_7
WH3_k127_4331797_1	373903.Hore_14310	7.971e-58	207.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia,3WAKB@53433|Halanaerobiales	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
WH3_k127_4331797_3	742727.HMPREF9447_00887	1.176e-20	94.0	COG4660@1|root,COG4660@2|Bacteria,4NHHP@976|Bacteroidetes,2FM8R@200643|Bacteroidia,4AMRD@815|Bacteroidaceae	976|Bacteroidetes	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
WH3_k127_4366723_1	405948.SACE_0363	3.535e-31	135.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,4DY0E@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
WH3_k127_4366723_0	655815.ZPR_1012	7.283e-37	143.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
WH3_k127_4399537_5	927677.ALVU02000001_gene800	3.268e-10	66.0	COG0204@1|root,COG0204@2|Bacteria,1G173@1117|Cyanobacteria,1H5BP@1142|Synechocystis	1117|Cyanobacteria	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WH3_k127_4399537_1	344747.PM8797T_30347	4.295e-56	203.0	COG0283@1|root,COG0283@2|Bacteria,2IZ6S@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
WH3_k127_4399537_3	237368.SCABRO_03331	1.519e-47	193.0	COG0706@1|root,COG0706@2|Bacteria,2IYA0@203682|Planctomycetes	203682|Planctomycetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,PDZ_2,YidC_periplas
WH3_k127_4399537_0	1142394.PSMK_14290	1.733e-80	275.0	COG0639@1|root,COG0639@2|Bacteria,2IYH6@203682|Planctomycetes	203682|Planctomycetes	T	COG0639 Diadenosine tetraphosphatase and related	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
WH3_k127_4399537_4	1445613.JALM01000006_gene583	9.483e-14	81.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4DXZ6@85010|Pseudonocardiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
WH3_k127_4399537_2	349741.Amuc_0679	2.04e-49	181.0	COG1137@1|root,COG1137@2|Bacteria,46SDI@74201|Verrucomicrobia,2IU2S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
WH3_k127_4409746_0	1167006.UWK_02703	5.32e-59	211.0	COG3157@1|root,COG3157@2|Bacteria,1MXFB@1224|Proteobacteria,42Q89@68525|delta/epsilon subdivisions,2X5KY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
WH3_k127_4409746_1	314230.DSM3645_08617	4.992e-48	184.0	COG0009@1|root,COG0394@1|root,COG0009@2|Bacteria,COG0394@2|Bacteria,2IX5F@203682|Planctomycetes	203682|Planctomycetes	T	Belongs to the SUA5 family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc,Sua5_yciO_yrdC
WH3_k127_4436663_0	237368.SCABRO_00645	1.608e-56	211.0	COG1030@1|root,COG1030@2|Bacteria,2IWTY@203682|Planctomycetes	203682|Planctomycetes	O	ClpP class	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,SDH_sah
WH3_k127_4470477_0	1267534.KB906761_gene1195	0.0	1436.0	COG3957@1|root,COG3957@2|Bacteria,3Y3XU@57723|Acidobacteria,2JKSB@204432|Acidobacteriia	204432|Acidobacteriia	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
WH3_k127_4509996_0	1210884.HG799472_gene14899	1.516e-13	83.0	COG1706@1|root,COG1706@2|Bacteria,2IY0C@203682|Planctomycetes	203682|Planctomycetes	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	-	-	-	-	-	-	-	-	-	-	-	-	FlgI,HEAT_2
WH3_k127_4543940_0	640081.Dsui_1549	1.141e-40	169.0	COG0834@1|root,COG2202@1|root,COG2203@1|root,COG4251@1|root,COG0834@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,2WGSC@28216|Betaproteobacteria	28216|Betaproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
WH3_k127_4548722_0	370438.PTH_1466	1.482e-83	283.0	COG0463@1|root,COG0463@2|Bacteria,1UI8D@1239|Firmicutes,247P4@186801|Clostridia,267CB@186807|Peptococcaceae	186801|Clostridia	H	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH3_k127_4548722_1	1121396.KB893111_gene1922	7.581e-09	59.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2WIVG@28221|Deltaproteobacteria,2MHTA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
WH3_k127_4561070_0	1123073.KB899241_gene3162	6.524e-10	66.0	COG3156@1|root,COG3156@2|Bacteria,1RJRE@1224|Proteobacteria,1S6CB@1236|Gammaproteobacteria,1X4D4@135614|Xanthomonadales	135614|Xanthomonadales	U	Type II secretion system protein K	xpsK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
WH3_k127_458864_0	189425.PGRAT_08465	1.833e-63	243.0	COG3291@1|root,COG3420@1|root,COG5492@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,COG5492@2|Bacteria,1VR20@1239|Firmicutes,4HVGA@91061|Bacilli,26V79@186822|Paenibacillaceae	91061|Bacilli	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2
WH3_k127_4612726_3	1121121.KB894300_gene1639	5.592e-14	73.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,26QG9@186822|Paenibacillaceae	91061|Bacilli	L	ATPase, AAA	yrvN	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
WH3_k127_4612726_2	1120973.AQXL01000105_gene2561	1.802e-30	128.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,27A2H@186823|Alicyclobacillaceae	91061|Bacilli	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
WH3_k127_4612726_1	1142394.PSMK_18550	9.428e-40	164.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,2J0C4@203682|Planctomycetes	203682|Planctomycetes	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
WH3_k127_4612726_4	400682.PAC_15721263	5.013e-07	61.0	28NKM@1|root,2QV6D@2759|Eukaryota,38E1F@33154|Opisthokonta,3BGJX@33208|Metazoa	33208|Metazoa	-	-	VWA3B	-	-	-	-	-	-	-	-	-	-	-	DUF4537,VWA_3
WH3_k127_4612726_0	1225785.CM001983_gene720	5.171e-40	156.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,2JDAS@204037|Dickeya	1236|Gammaproteobacteria	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iEcSMS35_1347.EcSMS35_2767	NAD_kinase
WH3_k127_4615390_1	247490.KSU1_D0697	1.644e-43	167.0	COG1181@1|root,COG1181@2|Bacteria,2IZHT@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
WH3_k127_4615390_0	521674.Plim_0011	5.21e-88	300.0	COG0812@1|root,COG0812@2|Bacteria,2IYGQ@203682|Planctomycetes	203682|Planctomycetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
WH3_k127_4615390_2	247490.KSU1_D0698	1.474e-26	113.0	COG0773@1|root,COG0773@2|Bacteria,2IYEH@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WH3_k127_4628829_0	1210884.HG799469_gene13944	0.0	1106.0	COG0542@1|root,COG0542@2|Bacteria,2IXHI@203682|Planctomycetes	203682|Planctomycetes	O	with chaperone activity ATP-binding	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
WH3_k127_4662906_0	869213.JCM21142_72658	1.186e-121	397.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WH3_k127_4662906_1	1267534.KB906757_gene1115	5.936e-05	47.0	COG0673@1|root,COG0673@2|Bacteria,3Y6RA@57723|Acidobacteria,2JMMQ@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
WH3_k127_466559_2	194867.ALBQ01000011_gene384	2.419e-05	46.0	COG4206@1|root,COG4206@2|Bacteria,1R47X@1224|Proteobacteria,2TW4W@28211|Alphaproteobacteria,2JZYG@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
WH3_k127_466559_1	879212.DespoDRAFT_00200	5.858e-25	108.0	COG0748@1|root,COG0748@2|Bacteria,1N2JV@1224|Proteobacteria,42TYW@68525|delta/epsilon subdivisions,2WQEM@28221|Deltaproteobacteria,2MK6D@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
WH3_k127_466559_0	589865.DaAHT2_0096	7.236e-52	187.0	COG2159@1|root,COG2159@2|Bacteria,1RDRH@1224|Proteobacteria,42T80@68525|delta/epsilon subdivisions,2WPGY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
WH3_k127_4666874_1	986075.CathTA2_2297	5.975e-49	184.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli	91061|Bacilli	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
WH3_k127_4666874_2	237368.SCABRO_01473	1.485e-18	91.0	COG2001@1|root,COG2001@2|Bacteria,2J1IV@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
WH3_k127_4666874_0	1121451.DESAM_21376	5.02e-193	614.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,43EBY@68525|delta/epsilon subdivisions,2X7W0@28221|Deltaproteobacteria,2MHDJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
WH3_k127_4686293_1	886293.Sinac_6467	4.052e-62	219.0	COG4956@1|root,COG4956@2|Bacteria,2IXF3@203682|Planctomycetes	203682|Planctomycetes	S	Integral membrane protein (PIN domain superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	PIN_4,TRAM
WH3_k127_4686293_0	398767.Glov_2977	5.637e-120	396.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2WK37@28221|Deltaproteobacteria,43TKI@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WH3_k127_4696822_0	1408422.JHYF01000006_gene1212	6.378e-89	298.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,36DCX@31979|Clostridiaceae	186801|Clostridia	P	Phosphate transport system permease protein PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
WH3_k127_4696822_2	1294142.CINTURNW_2187	1.325e-83	284.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,36DJ4@31979|Clostridiaceae	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
WH3_k127_4696822_1	340177.Cag_0498	6.031e-86	291.0	COG1117@1|root,COG1117@2|Bacteria,1FEHB@1090|Chlorobi	1090|Chlorobi	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
WH3_k127_4696822_3	237368.SCABRO_01122	4.78e-51	186.0	COG0704@1|root,COG0704@2|Bacteria,2IYX4@203682|Planctomycetes	203682|Planctomycetes	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
WH3_k127_4699031_0	522306.CAP2UW1_3076	9.186e-53	198.0	COG0310@1|root,COG0310@2|Bacteria,1R70A@1224|Proteobacteria,2VS85@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Cobalamin (Vitamin B12) biosynthesis CbiM protein	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
WH3_k127_4718552_0	1041930.Mtc_2239	5.162e-146	472.0	COG0187@1|root,arCOG04371@2157|Archaea,2XSVX@28890|Euryarchaeota,2N9BE@224756|Methanomicrobia	224756|Methanomicrobia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WH3_k127_4718552_1	1142394.PSMK_03840	7.891e-88	302.0	COG0592@1|root,COG0592@2|Bacteria,2IY9S@203682|Planctomycetes	203682|Planctomycetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
WH3_k127_474748_0	1405498.SSIM_08085	3.652e-51	185.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,4GY5I@90964|Staphylococcaceae	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
WH3_k127_474748_1	344747.PM8797T_28444	2.583e-34	135.0	COG0335@1|root,COG0335@2|Bacteria,2IZVX@203682|Planctomycetes	203682|Planctomycetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
WH3_k127_474748_2	702459.BBPR_1221	8.517e-16	81.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4D191@85004|Bifidobacteriales	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
WH3_k127_4776547_1	237368.SCABRO_01704	2.396e-59	211.0	COG0042@1|root,COG0042@2|Bacteria,2IYH0@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
WH3_k127_4776547_0	237368.SCABRO_02572	6.226e-193	617.0	COG0119@1|root,COG0119@2|Bacteria,2IXBC@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
WH3_k127_4776547_2	794903.OPIT5_20185	0.0002017	51.0	COG2165@1|root,COG2165@2|Bacteria,46WQM@74201|Verrucomicrobia,3K9N5@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
WH3_k127_4802906_2	1122244.AUGF01000003_gene882	8.729e-05	50.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,3NKF2@468|Moraxellaceae	1236|Gammaproteobacteria	M	HlyD membrane-fusion protein of T1SS	prsE	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
WH3_k127_4802906_0	1121353.H924_00360	6.315e-29	124.0	COG1285@1|root,COG1285@2|Bacteria,2GM32@201174|Actinobacteria,22MCM@1653|Corynebacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
WH3_k127_4802906_1	411471.SUBVAR_04048	3.242e-05	49.0	COG5036@1|root,COG5036@2|Bacteria,1TYFN@1239|Firmicutes,24AGZ@186801|Clostridia,3WJCF@541000|Ruminococcaceae	186801|Clostridia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
WH3_k127_4809416_2	871968.DESME_04695	2.562e-56	204.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,260BN@186807|Peptococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WH3_k127_4809416_0	1239962.C943_03350	6.27e-119	388.0	28HAW@1|root,2Z7N4@2|Bacteria,4NG29@976|Bacteroidetes,47TIM@768503|Cytophagia	976|Bacteroidetes	S	KilA-N	-	-	-	-	-	-	-	-	-	-	-	-	KilA-N
WH3_k127_4809416_1	1131269.AQVV01000004_gene576	5.625e-85	294.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
WH3_k127_4838896_2	335543.Sfum_3691	7.877e-10	64.0	COG0705@1|root,COG0705@2|Bacteria,1Q5NI@1224|Proteobacteria,431IG@68525|delta/epsilon subdivisions,2WWXK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WH3_k127_4838896_3	61853.ENSNLEP00000020000	8.613e-05	54.0	28N19@1|root,2QUK7@2759|Eukaryota,38HHN@33154|Opisthokonta,3BCH4@33208|Metazoa,3CRT4@33213|Bilateria,47ZJY@7711|Chordata,48WI3@7742|Vertebrata,3J4I2@40674|Mammalia,35DQV@314146|Euarchontoglires,4MATQ@9443|Primates	33208|Metazoa	T	Lipase	PNLIPRP2	GO:0003674,GO:0003824,GO:0004620,GO:0004806,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0006950,GO:0006952,GO:0006968,GO:0007275,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009605,GO:0009719,GO:0009725,GO:0009791,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0012505,GO:0012506,GO:0014070,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0019374,GO:0019376,GO:0019377,GO:0019637,GO:0030141,GO:0030659,GO:0030667,GO:0031090,GO:0031410,GO:0031667,GO:0031960,GO:0031982,GO:0032094,GO:0032501,GO:0032502,GO:0033993,GO:0042221,GO:0042588,GO:0042589,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043434,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044258,GO:0044421,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0046434,GO:0046466,GO:0046872,GO:0047372,GO:0047714,GO:0048545,GO:0048856,GO:0050896,GO:0051384,GO:0052689,GO:0071704,GO:0097708,GO:0098588,GO:0098805,GO:0099503,GO:1901135,GO:1901136,GO:1901575,GO:1901652,GO:1901698,GO:1901700,GO:1903509	3.1.1.3	ko:K14073,ko:K14074,ko:K14075	ko00561,ko01100,ko04972,ko04975,ko04977,map00561,map01100,map04972,map04975,map04977	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase,PLAT
WH3_k127_4838896_1	1499967.BAYZ01000024_gene282	3.15e-18	94.0	COG5373@1|root,COG5373@2|Bacteria	2|Bacteria	KLT	membrane	Otg1	-	-	-	-	-	-	-	-	-	-	-	DUF2339,DUF4167
WH3_k127_4839264_0	583355.Caka_3034	7.89e-94	320.0	COG2805@1|root,COG2805@2|Bacteria,46S5Q@74201|Verrucomicrobia,3K79X@414999|Opitutae	414999|Opitutae	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WH3_k127_4839264_1	1142394.PSMK_10550	3.464e-73	254.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,2IXA1@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP,HATPase_c,HisKA
WH3_k127_4873648_0	84531.JMTZ01000001_gene2271	1.823e-05	57.0	COG3291@1|root,COG3420@1|root,COG4935@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.11.10,3.4.21.50,3.4.24.25,3.4.24.3	ko:K01337,ko:K01387,ko:K05994,ko:K08604,ko:K14645,ko:K20276	ko02024,ko05110,ko05111,map02024,map05110,map05111	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02042,ko03110	-	-	-	Inhibitor_I9,LVIVD,PKD,P_proprotein,Peptidase_M14,Peptidase_S8
WH3_k127_4922070_7	314232.SKA53_13218	2.868e-05	47.0	2CHP8@1|root,2ZAVY@2|Bacteria,1PQTH@1224|Proteobacteria,2U4NQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4922070_5	1142394.PSMK_08320	5.997e-13	70.0	COG0267@1|root,COG0267@2|Bacteria,2J1HX@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL33 family	-	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
WH3_k127_4922070_4	530564.Psta_2558	5.115e-14	79.0	COG0690@1|root,COG0690@2|Bacteria,2J0E7@203682|Planctomycetes	203682|Planctomycetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
WH3_k127_4922070_1	1142394.PSMK_08340	4.161e-61	215.0	COG0250@1|root,COG0250@2|Bacteria,2IZ9N@203682|Planctomycetes	203682|Planctomycetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
WH3_k127_4922070_2	886293.Sinac_0505	4.468e-59	207.0	COG0080@1|root,COG0080@2|Bacteria,2IZ97@203682|Planctomycetes	203682|Planctomycetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
WH3_k127_4922070_0	243090.RB12839	6.474e-74	256.0	COG0081@1|root,COG0081@2|Bacteria,2IYQK@203682|Planctomycetes	203682|Planctomycetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
WH3_k127_4922070_6	66692.ABC0139	5.617e-07	58.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,1ZBGK@1386|Bacillus	91061|Bacilli	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
WH3_k127_4922070_3	243090.RB12842	2.448e-16	80.0	COG0222@1|root,COG0222@2|Bacteria,2J0AK@203682|Planctomycetes	203682|Planctomycetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
WH3_k127_4929303_1	192952.MM_0490	4.766e-12	76.0	COG1413@1|root,arCOG02966@2157|Archaea	2157|Archaea	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
WH3_k127_4929303_0	886293.Sinac_2241	1.093e-15	91.0	COG0795@1|root,COG0795@2|Bacteria,2IZJF@203682|Planctomycetes	203682|Planctomycetes	S	Permease YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
WH3_k127_4929303_2	1123508.JH636445_gene6662	4.085e-10	68.0	COG0795@1|root,COG0795@2|Bacteria,2IZHF@203682|Planctomycetes	203682|Planctomycetes	S	Permease YjgP YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
WH3_k127_4948658_0	204669.Acid345_3823	1.919e-67	243.0	COG0438@1|root,COG0438@2|Bacteria,3Y5K5@57723|Acidobacteria,2JNE3@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4948658_1	693746.OBV_34610	1.956e-14	74.0	COG2361@1|root,COG2361@2|Bacteria,1U4U6@1239|Firmicutes,259IR@186801|Clostridia,2N8NM@216572|Oscillospiraceae	186801|Clostridia	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
WH3_k127_4959393_4	192952.MM_2923	8.07e-12	75.0	COG3391@1|root,arCOG02527@1|root,arCOG02527@2157|Archaea,arCOG02562@2157|Archaea,2XVNE@28890|Euryarchaeota	28890|Euryarchaeota	S	40-residue YVTN family beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
WH3_k127_4959393_1	247490.KSU1_B0080	1.577e-29	119.0	2E3J3@1|root,32YHH@2|Bacteria,2J485@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4959393_2	247490.KSU1_B0079	2.529e-17	83.0	COG5428@1|root,COG5428@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
WH3_k127_4959393_3	1120965.AUBV01000005_gene1864	6.961e-13	72.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
WH3_k127_4959393_0	1396141.BATP01000049_gene3489	7.696e-110	362.0	COG0451@1|root,COG0451@2|Bacteria,46UCR@74201|Verrucomicrobia,2IWKH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	NmrA-like family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WH3_k127_4966726_0	237368.SCABRO_03203	1.845e-97	329.0	COG0072@1|root,COG0072@2|Bacteria,2IX0Q@203682|Planctomycetes	203682|Planctomycetes	J	Phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
WH3_k127_4979784_0	292459.STH2174	5.841e-71	266.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia	186801|Clostridia	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
WH3_k127_4992324_0	1123288.SOV_1c08080	2.027e-67	241.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,4H31M@909932|Negativicutes	909932|Negativicutes	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_4,Fer4_8,RnfC_N,SLBB
WH3_k127_500709_3	1142394.PSMK_22360	5.509e-06	50.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2J0AY@203682|Planctomycetes	203682|Planctomycetes	D	Capsular exopolysaccharide family	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	CbiA
WH3_k127_500709_1	1238184.CM001792_gene2136	3.856e-107	355.0	COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,4HCJE@91061|Bacilli,23NBV@182709|Oceanobacillus	91061|Bacilli	M	NmrA-like family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WH3_k127_500709_2	497964.CfE428DRAFT_3578	3.986e-96	333.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
WH3_k127_500709_0	661478.OP10G_1273	5.756e-178	574.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,Lyase_8,Lyase_8_C,Lyase_8_N,NPCBM_assoc
WH3_k127_5010689_0	1123508.JH636444_gene5345	2.66e-30	127.0	2DN68@1|root,32UID@2|Bacteria,2J012@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5016391_1	1206730.BAGA01000023_gene5652	0.0001958	47.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4FVM6@85025|Nocardiaceae	201174|Actinobacteria	L	DNA polymerase Ligase (LigD)	ligD	GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
WH3_k127_5016391_0	395494.Galf_2854	1.407e-40	162.0	COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,2VKY4@28216|Betaproteobacteria	28216|Betaproteobacteria	H	PFAM UbiA prenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
WH3_k127_5021432_0	247490.KSU1_D0623	2.401e-145	466.0	COG0059@1|root,COG0059@2|Bacteria,2IXH2@203682|Planctomycetes	203682|Planctomycetes	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
WH3_k127_5021432_1	530564.Psta_3639	4.599e-71	254.0	COG1459@1|root,COG1459@2|Bacteria,2IYHA@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
WH3_k127_5021432_2	868864.Dester_0385	0.0002643	43.0	COG2804@1|root,COG2804@2|Bacteria,2G4H7@200783|Aquificae	200783|Aquificae	NU	PFAM Type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
WH3_k127_5035750_1	926569.ANT_06290	3.637e-136	439.0	COG0451@1|root,COG0451@2|Bacteria,2G7M6@200795|Chloroflexi	200795|Chloroflexi	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
WH3_k127_5035750_0	1047013.AQSP01000133_gene2141	1.364e-190	617.0	COG2605@1|root,COG2605@2|Bacteria	2|Bacteria	G	GHMP kinase	fkp	-	2.7.1.52	ko:K05305	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R03161	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Fucokinase,GHMP_kinases_C,GHMP_kinases_N
WH3_k127_5036719_4	886293.Sinac_0463	1.665e-44	164.0	COG0099@1|root,COG0099@2|Bacteria,2IZK8@203682|Planctomycetes	203682|Planctomycetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
WH3_k127_5036719_3	1210884.HG799465_gene12004	3.805e-50	181.0	COG0100@1|root,COG0100@2|Bacteria,2IZCP@203682|Planctomycetes	203682|Planctomycetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
WH3_k127_5036719_2	646529.Desaci_0517	2.316e-62	220.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,260U9@186807|Peptococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
WH3_k127_5036719_1	1142394.PSMK_23760	2.487e-123	404.0	COG0202@1|root,COG0202@2|Bacteria,2IXPQ@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
WH3_k127_5036719_7	272942.RCAP_rcc00327	1.886e-28	119.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria,1FBUB@1060|Rhodobacter	28211|Alphaproteobacteria	J	PFAM ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
WH3_k127_5036719_6	1379281.AVAG01000038_gene777	1.664e-33	134.0	COG0537@1|root,COG0537@2|Bacteria,1PDTP@1224|Proteobacteria,42UAD@68525|delta/epsilon subdivisions,2WQRN@28221|Deltaproteobacteria,2MBWX@213115|Desulfovibrionales	28221|Deltaproteobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
WH3_k127_5036719_8	1229780.BN381_130143	1.612e-06	51.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5036719_0	909663.KI867150_gene1654	1.526e-240	751.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,42M83@68525|delta/epsilon subdivisions,2WIZE@28221|Deltaproteobacteria,2MR55@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
WH3_k127_5036719_5	1168034.FH5T_16565	1.578e-43	163.0	COG1943@1|root,COG1943@2|Bacteria,4NPPG@976|Bacteroidetes,2FTKF@200643|Bacteroidia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WH3_k127_5059922_0	96561.Dole_3091	1.676e-93	309.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,42TG6@68525|delta/epsilon subdivisions,2WQ8T@28221|Deltaproteobacteria,2MNB0@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
WH3_k127_5059922_1	96561.Dole_3091	2.728e-36	139.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,42TG6@68525|delta/epsilon subdivisions,2WQ8T@28221|Deltaproteobacteria,2MNB0@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
WH3_k127_5071918_0	439235.Dalk_3029	1.397e-208	663.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,42M5P@68525|delta/epsilon subdivisions,2WM1R@28221|Deltaproteobacteria,2MID5@213118|Desulfobacterales	28221|Deltaproteobacteria	KL	SNF2 Helicase protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
WH3_k127_5091279_1	706587.Desti_0062	1.453e-141	452.0	COG0458@1|root,COG0458@2|Bacteria,1NPMZ@1224|Proteobacteria,42NF3@68525|delta/epsilon subdivisions,2WM4C@28221|Deltaproteobacteria,2MQ8X@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthetase large chain, oligomerisation	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0661	CPSase_L_D2,CPSase_L_D3,MGS
WH3_k127_5091279_4	742726.HMPREF9448_00701	8.881e-38	152.0	2DMX9@1|root,32U7V@2|Bacteria,4NQBF@976|Bacteroidetes,2FR04@200643|Bacteroidia,22Y9F@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5091279_2	314262.MED193_03567	4.725e-42	166.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
WH3_k127_5091279_3	485918.Cpin_0563	5.781e-39	156.0	COG3509@1|root,COG3509@2|Bacteria,4NENB@976|Bacteroidetes,1IRXD@117747|Sphingobacteriia	976|Bacteroidetes	Q	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
WH3_k127_5094059_0	886293.Sinac_1633	1.11e-70	259.0	COG3386@1|root,COG3386@2|Bacteria,2J56X@203682|Planctomycetes	203682|Planctomycetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5094059_1	360107.CHAB381_0023	8.08e-35	138.0	COG1951@1|root,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,42MC7@68525|delta/epsilon subdivisions,2YN8Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Fumarate hydratase	ttdA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
WH3_k127_5097886_0	517418.Ctha_0544	5.75e-206	657.0	COG0449@1|root,COG0449@2|Bacteria,1FDCR@1090|Chlorobi	1090|Chlorobi	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
WH3_k127_5097886_2	1167006.UWK_03002	1.59e-32	133.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2WP41@28221|Deltaproteobacteria,2MK62@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
WH3_k127_5097886_1	880070.Cycma_4699	2.947e-168	543.0	COG3540@1|root,COG3540@2|Bacteria,4NDUS@976|Bacteroidetes	976|Bacteroidetes	P	COG3540 Phosphodiesterase alkaline phosphatase D	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
WH3_k127_5097886_3	583355.Caka_1113	7.349e-25	106.0	2ERTX@1|root,33JD4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5101192_1	1142394.PSMK_06240	1.14e-22	105.0	2DD6P@1|root,2ZGSW@2|Bacteria	2|Bacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
WH3_k127_5101192_0	886293.Sinac_3923	7.626e-24	111.0	COG4219@1|root,COG4219@2|Bacteria,2J2DC@203682|Planctomycetes	203682|Planctomycetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
WH3_k127_5116946_1	1220534.B655_1152	1.271e-70	247.0	COG0159@1|root,arCOG01086@2157|Archaea,2XTAW@28890|Euryarchaeota,23NJK@183925|Methanobacteria	183925|Methanobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
WH3_k127_5116946_0	1254432.SCE1572_07860	2.395e-154	497.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2WJJA@28221|Deltaproteobacteria,2YU86@29|Myxococcales	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WH3_k127_5116946_2	404380.Gbem_1960	1.25e-46	179.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2WNPH@28221|Deltaproteobacteria,43U0C@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
WH3_k127_5116946_3	1280679.ATVX01000003_gene3177	2.662e-24	106.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,4BW9I@830|Butyrivibrio	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,Glycos_trans_3N,Glycos_transf_3
WH3_k127_5123216_0	717772.THIAE_02775	2.148e-50	194.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,463V9@72273|Thiotrichales	72273|Thiotrichales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
WH3_k127_5123216_1	237368.SCABRO_01639	6.758e-31	131.0	COG2211@1|root,COG2211@2|Bacteria,2IY9C@203682|Planctomycetes	203682|Planctomycetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH3_k127_5131248_0	290397.Adeh_4049	8.989e-33	138.0	COG1651@1|root,COG1651@2|Bacteria,1RKYF@1224|Proteobacteria,42T64@68525|delta/epsilon subdivisions,2WP82@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
WH3_k127_515096_1	103690.17130433	3.63e-06	55.0	COG1366@1|root,COG1366@2|Bacteria,1G7NW@1117|Cyanobacteria,1HP1W@1161|Nostocales	1117|Cyanobacteria	T	Anti-sigma-factor antagonist	-	-	-	-	-	-	-	-	-	-	-	-	STAS
WH3_k127_515096_0	1123242.JH636437_gene6062	1.129e-32	132.0	COG0571@1|root,COG0571@2|Bacteria,2IYW1@203682|Planctomycetes	203682|Planctomycetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
WH3_k127_5190512_0	1123242.JH636438_gene5699	5.785e-81	286.0	COG2804@1|root,COG2804@2|Bacteria,2IXVD@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE
WH3_k127_5190512_1	1034943.BN1094_02965	6.365e-13	74.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1JDKU@118969|Legionellales	118969|Legionellales	U	Secretin and TonB N terminus short domain	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
WH3_k127_5207052_0	1125863.JAFN01000001_gene3410	1.282e-77	270.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
WH3_k127_5207052_1	886293.Sinac_5300	8.511e-75	261.0	COG3494@1|root,COG3494@2|Bacteria,2IXGX@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
WH3_k127_5210551_1	595460.RRSWK_03184	2.025e-05	51.0	2B8BF@1|root,321K5@2|Bacteria,2IZTE@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function DUF2617	-	-	-	-	-	-	-	-	-	-	-	-	DUF2617
WH3_k127_5210551_0	472759.Nhal_1652	5.337e-80	282.0	COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,1S1F9@1236|Gammaproteobacteria,1X1BJ@135613|Chromatiales	135613|Chromatiales	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
WH3_k127_5212370_0	575540.Isop_0551	1.162e-59	209.0	COG0055@1|root,COG0055@2|Bacteria,2IY7P@203682|Planctomycetes	203682|Planctomycetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
WH3_k127_5212370_1	3055.DAA00924	1.098e-10	68.0	COG0355@1|root,KOG1758@2759|Eukaryota,37UFP@33090|Viridiplantae,34MRU@3041|Chlorophyta	3041|Chlorophyta	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
WH3_k127_5224909_0	1313304.CALK_2525	1.215e-73	260.0	2DBEW@1|root,2Z8UY@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4874)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874
WH3_k127_523140_2	1125863.JAFN01000001_gene2000	6.359e-31	125.0	COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,42MXC@68525|delta/epsilon subdivisions,2WJJF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
WH3_k127_523140_0	865861.AZSU01000001_gene359	3.884e-68	237.0	COG2209@1|root,COG2209@2|Bacteria,1UYUQ@1239|Firmicutes,24CMI@186801|Clostridia,36RAD@31979|Clostridiaceae	186801|Clostridia	C	Rnf-Nqr subunit, membrane protein	-	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
WH3_k127_523140_1	865861.AZSU01000001_gene358	1.264e-66	233.0	COG1347@1|root,COG1347@2|Bacteria,1UPN4@1239|Firmicutes,25HJG@186801|Clostridia,36QN3@31979|Clostridiaceae	186801|Clostridia	C	Rnf-Nqr subunit, membrane protein	-	-	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
WH3_k127_523140_3	2423.NA23_0200585	6.38e-21	103.0	COG2869@1|root,COG2869@2|Bacteria,2GCZN@200918|Thermotogae	200918|Thermotogae	C	PFAM FMN-binding domain	-	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
WH3_k127_523140_4	865861.AZSU01000001_gene356	1.117e-19	92.0	COG4658@1|root,COG4658@2|Bacteria,1V08Y@1239|Firmicutes,24DPB@186801|Clostridia,36R19@31979|Clostridiaceae	186801|Clostridia	C	NQR2, RnfD, RnfE family	-	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
WH3_k127_5263085_0	382464.ABSI01000013_gene1719	1.823e-106	354.0	COG0673@1|root,COG0673@2|Bacteria,46TK3@74201|Verrucomicrobia,2IVGR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WH3_k127_5263085_1	243090.RB4846	1.035e-88	312.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
WH3_k127_5304871_0	1198452.Jab_2c32030	1.005e-169	552.0	COG4225@1|root,COG4225@2|Bacteria,1NSJK@1224|Proteobacteria,2W99X@28216|Betaproteobacteria,475TV@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4861)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4861,Glyco_hydro_88
WH3_k127_5304871_1	639030.JHVA01000001_gene625	5.744e-110	362.0	COG3717@1|root,COG3717@2|Bacteria,3Y48D@57723|Acidobacteria,2JI6P@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
WH3_k127_5304871_2	521460.Athe_2383	1.312e-32	129.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia,42GQ3@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM Short-chain dehydrogenase reductase SDR	kduD	-	1.1.1.127,1.1.1.69	ko:K00046,ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
WH3_k127_5327405_0	1535422.ND16A_0310	2.042e-72	258.0	COG3325@1|root,COG3325@2|Bacteria	2|Bacteria	G	chitin binding	chiA	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
WH3_k127_5336438_1	1173024.KI912152_gene396	1.642e-24	111.0	COG2374@1|root,COG2374@2|Bacteria,1GBH9@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF3616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616
WH3_k127_5336438_0	882378.RBRH_01992	1.132e-124	413.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1K3N3@119060|Burkholderiaceae	28216|Betaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
WH3_k127_5336438_2	1210884.HG799463_gene10266	3.443e-21	95.0	COG0227@1|root,COG0227@2|Bacteria,2J0SS@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
WH3_k127_5407778_1	1117647.M5M_16595	2.349e-72	258.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,1JAKV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WH3_k127_5407778_0	1304880.JAGB01000001_gene369	1.015e-125	421.0	COG3250@1|root,COG3250@2|Bacteria,1TRQF@1239|Firmicutes,248UC@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
WH3_k127_5422348_0	344747.PM8797T_01709	7.325e-88	305.0	COG1519@1|root,COG1519@2|Bacteria,2IYCJ@203682|Planctomycetes	203682|Planctomycetes	M	transferase	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
WH3_k127_5422348_1	886293.Sinac_6200	6.599e-38	146.0	COG0231@1|root,COG0231@2|Bacteria,2IZ4X@203682|Planctomycetes	203682|Planctomycetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
WH3_k127_543326_0	886293.Sinac_3038	2.097e-129	424.0	COG0044@1|root,COG0044@2|Bacteria,2IWS9@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
WH3_k127_543326_2	765420.OSCT_0628	2.766e-05	52.0	COG3688@1|root,COG3688@2|Bacteria,2G95S@200795|Chloroflexi,375WR@32061|Chloroflexia	32061|Chloroflexia	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
WH3_k127_543326_1	313590.MED134_07194	4.089e-16	80.0	COG0673@1|root,COG0673@2|Bacteria,4NE07@976|Bacteroidetes,1HY1C@117743|Flavobacteriia,37DN8@326319|Dokdonia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WH3_k127_5448143_2	1089553.Tph_c19060	6.12e-10	63.0	COG2378@1|root,COG2378@2|Bacteria,1TT23@1239|Firmicutes,248A8@186801|Clostridia,42FKV@68295|Thermoanaerobacterales	186801|Clostridia	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
WH3_k127_5448143_0	1125863.JAFN01000001_gene825	1.215e-47	181.0	arCOG09742@1|root,2ZBGR@2|Bacteria,1R9H3@1224|Proteobacteria,42XHN@68525|delta/epsilon subdivisions,2WT8H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5448143_1	1469948.JPNB01000001_gene2313	3.501e-13	72.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,24BGM@186801|Clostridia,36GJR@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
WH3_k127_5465564_0	373903.Hore_01810	1.436e-162	520.0	COG1905@1|root,COG3383@1|root,COG4624@1|root,COG1905@2|Bacteria,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,3WB4D@53433|Halanaerobiales	186801|Clostridia	C	Iron only hydrogenase large subunit, C-terminal domain	-	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_7,NADH-G_4Fe-4S_3
WH3_k127_5465564_1	573413.Spirs_0354	4.326e-129	416.0	COG1894@1|root,COG1894@2|Bacteria,2J9M8@203691|Spirochaetes	203691|Spirochaetes	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
WH3_k127_5470878_0	247490.KSU1_C1120	1.002e-68	242.0	COG0289@1|root,COG0289@2|Bacteria,2IX9G@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
WH3_k127_5470878_2	886293.Sinac_3024	7.552e-12	68.0	2E607@1|root,330PM@2|Bacteria,2J0MD@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5470878_1	1232410.KI421416_gene2600	2.137e-36	144.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,42NTB@68525|delta/epsilon subdivisions,2WKNX@28221|Deltaproteobacteria,43U98@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
WH3_k127_5526816_1	927658.AJUM01000046_gene10	1.968e-49	175.0	28I5V@1|root,2Z891@2|Bacteria,4NF4U@976|Bacteroidetes,2FPB8@200643|Bacteroidia,3XIWU@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 9	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9
WH3_k127_5526816_0	883126.HMPREF9710_02800	2.918e-58	213.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Lipase_GDSL_2
WH3_k127_5541944_0	574087.Acear_2132	1.161e-215	685.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1TQXK@1239|Firmicutes,25EK3@186801|Clostridia,3WBKH@53433|Halanaerobiales	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D3
WH3_k127_5554292_1	706587.Desti_0793	7.212e-43	168.0	COG2378@1|root,COG2378@2|Bacteria,1Q5CX@1224|Proteobacteria,43A64@68525|delta/epsilon subdivisions,2X25D@28221|Deltaproteobacteria,2MS4E@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
WH3_k127_5554292_0	1313304.CALK_1925	3.218e-70	244.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
WH3_k127_5554292_2	1235797.C816_02457	0.0001178	46.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,2N772@216572|Oscillospiraceae	186801|Clostridia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH3_k127_5571202_0	933262.AXAM01000049_gene3265	1.225e-101	338.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria,2MIGM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM lipopolysaccharide heptosyltransferase II	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WH3_k127_5571202_1	1123242.JH636434_gene4085	4.443e-34	136.0	COG0438@1|root,COG0438@2|Bacteria,2IXN1@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WH3_k127_5578982_2	1121405.dsmv_1738	4.277e-41	154.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2WNA5@28221|Deltaproteobacteria,2MK12@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
WH3_k127_5578982_0	1121422.AUMW01000039_gene2828	1.637e-80	272.0	COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia,261PG@186807|Peptococcaceae	186801|Clostridia	C	PFAM Rubrerythrin	rbr	GO:0003674,GO:0003824,GO:0004601,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0022900,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
WH3_k127_5578982_1	1499967.BAYZ01000151_gene1660	7.607e-45	167.0	COG0735@1|root,COG0735@2|Bacteria,2NQ8Z@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the Fur family	perR	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2000374,GO:2001141	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
WH3_k127_5603487_0	1463887.KL590085_gene537	6.382e-07	63.0	COG1361@1|root,COG2706@1|root,COG1361@2|Bacteria,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,VCBS
WH3_k127_5603487_1	28377.ENSACAP00000023172	9.192e-05	56.0	2CMRF@1|root,2QRK8@2759|Eukaryota,38BZ6@33154|Opisthokonta,3BC6D@33208|Metazoa,3CRA6@33213|Bilateria,4834K@7711|Chordata,48UZ9@7742|Vertebrata	33208|Metazoa	W	negative regulation of dendritic cell antigen processing and presentation	THBS1	GO:0000187,GO:0000302,GO:0001501,GO:0001525,GO:0001568,GO:0001666,GO:0001786,GO:0001817,GO:0001818,GO:0001819,GO:0001932,GO:0001934,GO:0001936,GO:0001937,GO:0001944,GO:0001952,GO:0001953,GO:0001968,GO:0002040,GO:0002376,GO:0002544,GO:0002576,GO:0002577,GO:0002578,GO:0002580,GO:0002581,GO:0002604,GO:0002605,GO:0002682,GO:0002683,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0002694,GO:0002696,GO:0003007,GO:0003151,GO:0003197,GO:0003416,GO:0003417,GO:0003674,GO:0005102,GO:0005178,GO:0005488,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005543,GO:0005575,GO:0005576,GO:0005577,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005886,GO:0006417,GO:0006464,GO:0006807,GO:0006810,GO:0006887,GO:0006897,GO:0006909,GO:0006911,GO:0006928,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0006979,GO:0007049,GO:0007050,GO:0007155,GO:0007162,GO:0007275,GO:0007507,GO:0007610,GO:0008150,GO:0008152,GO:0008201,GO:0008284,GO:0008285,GO:0008289,GO:0009266,GO:0009408,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009887,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009897,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010324,GO:0010466,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010594,GO:0010595,GO:0010596,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010632,GO:0010633,GO:0010634,GO:0010646,GO:0010647,GO:0010648,GO:0010746,GO:0010748,GO:0010749,GO:0010751,GO:0010752,GO:0010754,GO:0010755,GO:0010757,GO:0010758,GO:0010759,GO:0010762,GO:0010763,GO:0010810,GO:0010811,GO:0010812,GO:0010941,GO:0010942,GO:0010951,GO:0010955,GO:0012505,GO:0014070,GO:0016020,GO:0016043,GO:0016192,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0017015,GO:0017134,GO:0018149,GO:0019220,GO:0019222,GO:0019538,GO:0019838,GO:0019955,GO:0022402,GO:0022603,GO:0022610,GO:0023051,GO:0023056,GO:0023057,GO:0030141,GO:0030155,GO:0030162,GO:0030169,GO:0030193,GO:0030194,GO:0030198,GO:0030334,GO:0030335,GO:0030336,GO:0030511,GO:0031012,GO:0031091,GO:0031093,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031399,GO:0031401,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032026,GO:0032101,GO:0032102,GO:0032103,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032368,GO:0032369,GO:0032501,GO:0032502,GO:0032570,GO:0032655,GO:0032680,GO:0032695,GO:0032760,GO:0032879,GO:0032890,GO:0032891,GO:0032908,GO:0032914,GO:0032940,GO:0032991,GO:0033554,GO:0033555,GO:0033674,GO:0033993,GO:0034248,GO:0034250,GO:0034284,GO:0034599,GO:0034605,GO:0034614,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0034774,GO:0034976,GO:0035239,GO:0035265,GO:0035295,GO:0035690,GO:0036211,GO:0036293,GO:0040007,GO:0040011,GO:0040012,GO:0040013,GO:0040017,GO:0040036,GO:0040037,GO:0042035,GO:0042108,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042493,GO:0042534,GO:0042535,GO:0042802,GO:0042981,GO:0043030,GO:0043032,GO:0043062,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043086,GO:0043154,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043236,GO:0043269,GO:0043271,GO:0043277,GO:0043281,GO:0043394,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043535,GO:0043536,GO:0043537,GO:0043549,GO:0043652,GO:0044070,GO:0044087,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045055,GO:0045595,GO:0045637,GO:0045652,GO:0045727,GO:0045765,GO:0045766,GO:0045785,GO:0045786,GO:0045859,GO:0045860,GO:0045861,GO:0045937,GO:0046872,GO:0046903,GO:0048265,GO:0048266,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048646,GO:0048660,GO:0048661,GO:0048705,GO:0048731,GO:0048856,GO:0048870,GO:0050431,GO:0050678,GO:0050680,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050818,GO:0050820,GO:0050839,GO:0050840,GO:0050865,GO:0050867,GO:0050878,GO:0050896,GO:0050920,GO:0050921,GO:0050922,GO:0051049,GO:0051051,GO:0051093,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051271,GO:0051272,GO:0051336,GO:0051338,GO:0051346,GO:0051347,GO:0051592,GO:0051674,GO:0051716,GO:0051726,GO:0051893,GO:0051895,GO:0051896,GO:0051897,GO:0051917,GO:0051918,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060485,GO:0060548,GO:0061024,GO:0061041,GO:0061448,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070051,GO:0070052,GO:0070482,GO:0070613,GO:0070887,GO:0071241,GO:0071622,GO:0071634,GO:0071636,GO:0071675,GO:0071704,GO:0071731,GO:0071732,GO:0071813,GO:0071814,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0072341,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090049,GO:0090051,GO:0090092,GO:0090100,GO:0090109,GO:0090287,GO:0090288,GO:0090303,GO:0097366,GO:0097367,GO:0097708,GO:0098552,GO:0098657,GO:0098868,GO:0099024,GO:0099503,GO:1900046,GO:1900048,GO:1901342,GO:1901343,GO:1901564,GO:1901654,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901888,GO:1901889,GO:1902041,GO:1902043,GO:1902170,GO:1902531,GO:1902532,GO:1902533,GO:1903034,GO:1903036,GO:1903317,GO:1903318,GO:1903391,GO:1903392,GO:1903555,GO:1903557,GO:1903587,GO:1903588,GO:1903670,GO:1903671,GO:1903706,GO:1903792,GO:1903844,GO:1903846,GO:1903959,GO:1903960,GO:1904018,GO:1904035,GO:1904037,GO:1905521,GO:1905523,GO:1905952,GO:1905953,GO:2000026,GO:2000112,GO:2000116,GO:2000117,GO:2000145,GO:2000146,GO:2000147,GO:2000181,GO:2000191,GO:2000192,GO:2000351,GO:2000353,GO:2000377,GO:2000379,GO:2001026,GO:2001027,GO:2001233,GO:2001234,GO:2001235,GO:2001236,GO:2001237,GO:2001238	-	ko:K04659,ko:K16857	ko04015,ko04115,ko04145,ko04151,ko04350,ko04510,ko04512,ko05144,ko05165,ko05205,ko05206,ko05219,map04015,map04115,map04145,map04151,map04350,map04510,map04512,map05144,map05165,map05205,map05206,map05219	-	-	-	ko00000,ko00001,ko00536,ko04131,ko04147,ko04516	-	-	-	EGF_3,EGF_CA,TSP_1,TSP_3,TSP_C,VWC
WH3_k127_5614996_1	1056512.D515_00620	2.958e-07	60.0	COG1525@1|root,COG1525@2|Bacteria,1N0I9@1224|Proteobacteria,1S8DU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Staphylococcal nuclease homologue	-	-	-	-	-	-	-	-	-	-	-	-	SNase
WH3_k127_5614996_2	246194.CHY_1698	7.273e-07	59.0	COG1525@1|root,COG1525@2|Bacteria,1VASF@1239|Firmicutes,24G14@186801|Clostridia,42G1J@68295|Thermoanaerobacterales	186801|Clostridia	L	Staphylococcal nuclease homologue	nucH	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	Ada_Zn_binding,SNase
WH3_k127_562796_1	595460.RRSWK_01544	4.57e-68	237.0	COG0086@1|root,COG0086@2|Bacteria,2IXGN@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
WH3_k127_562796_3	1051632.TPY_0318	1.246e-51	188.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,3WCIE@538999|Clostridiales incertae sedis	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
WH3_k127_562796_2	247490.KSU1_C1204	3.612e-59	208.0	COG0049@1|root,COG0049@2|Bacteria,2IZ7I@203682|Planctomycetes	203682|Planctomycetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
WH3_k127_562796_0	289376.THEYE_A1449	4.144e-208	662.0	COG0480@1|root,COG0480@2|Bacteria,3J0EK@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WH3_k127_5652872_1	1232437.KL662076_gene3500	2.857e-17	98.0	COG0457@1|root,COG1729@1|root,COG3063@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG3063@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria,2MJAV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8,zinc_ribbon_4
WH3_k127_5652872_2	435591.BDI_2681	0.0007114	53.0	COG0457@1|root,COG0457@2|Bacteria,4NMG2@976|Bacteroidetes,2FP23@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_8
WH3_k127_5652872_0	1142394.PSMK_03350	3.008e-50	186.0	COG2148@1|root,COG2148@2|Bacteria,2IYWX@203682|Planctomycetes	2|Bacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
WH3_k127_566433_0	748449.Halha_1207	3.896e-118	390.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,3WA9E@53433|Halanaerobiales	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WH3_k127_5678438_3	1166018.FAES_1281	7.606e-27	115.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WH3_k127_5678438_2	697281.Mahau_0767	2.929e-96	329.0	COG0407@1|root,COG0407@2|Bacteria,1V4WM@1239|Firmicutes,24IZV@186801|Clostridia,42J2I@68295|Thermoanaerobacterales	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
WH3_k127_5678438_1	1340493.JNIF01000003_gene2219	1.28e-107	362.0	COG2271@1|root,COG2271@2|Bacteria,3Y2KA@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Major facilitator superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
WH3_k127_5678438_4	1235803.C825_02068	3.222e-12	76.0	COG2207@1|root,COG2207@2|Bacteria,4NGS3@976|Bacteroidetes,2FMQ2@200643|Bacteroidia,22WJF@171551|Porphyromonadaceae	976|Bacteroidetes	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
WH3_k127_5678438_0	471854.Dfer_2269	1.576e-307	961.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,47MPU@768503|Cytophagia	976|Bacteroidetes	G	glycoside hydrolase family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
WH3_k127_5679165_0	1349822.NSB1T_03835	1.267e-09	70.0	COG0457@1|root,COG0457@2|Bacteria,4NDVW@976|Bacteroidetes,2FMY8@200643|Bacteroidia,22WHK@171551|Porphyromonadaceae	976|Bacteroidetes	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
WH3_k127_5687521_0	1142394.PSMK_27380	5.656e-77	269.0	COG1109@1|root,COG1109@2|Bacteria,2IXRS@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WH3_k127_5687521_1	622637.KE124770_gene148	4.321e-58	207.0	COG1389@1|root,COG1389@2|Bacteria,1R6T0@1224|Proteobacteria	1224|Proteobacteria	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,HATPase_c_3,Topo-VIb_trans
WH3_k127_56930_1	237368.SCABRO_00123	1.369e-54	196.0	COG3225@1|root,COG3225@2|Bacteria,2IXSG@203682|Planctomycetes	203682|Planctomycetes	N	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_5,ABC_transp_aux
WH3_k127_56930_0	237368.SCABRO_00124	2.085e-103	340.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC2_membrane_5,ABC_transp_aux
WH3_k127_56930_2	237368.SCABRO_00125	1.086e-51	184.0	COG1131@1|root,COG1131@2|Bacteria,2IXQV@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH3_k127_5708892_0	237368.SCABRO_01739	3.774e-18	97.0	2DBYC@1|root,2ZBUF@2|Bacteria,2IZ15@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
WH3_k127_5708892_1	1230476.C207_00976	1.032e-13	72.0	COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,2TTR9@28211|Alphaproteobacteria,3JRY7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferase family 2	MA20_30090	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WH3_k127_5726571_0	44060.JODL01000009_gene1828	1.108e-52	191.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria	201174|Actinobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
WH3_k127_5734360_1	1056820.KB900641_gene615	7.022e-17	96.0	COG3693@1|root,COG3693@2|Bacteria,1Q4ED@1224|Proteobacteria,1SYNN@1236|Gammaproteobacteria,2PPXI@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	G	Glycosyl hydrolase family 10	cex	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_4_9,Glyco_hydro_10
WH3_k127_5734360_0	357808.RoseRS_4272	9.077e-63	243.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,2G88I@200795|Chloroflexi,3780V@32061|Chloroflexia	32061|Chloroflexia	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5734360_2	449447.MAE_01490	6.571e-09	56.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
WH3_k127_5747037_1	439235.Dalk_0655	5.147e-110	364.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2WJ2S@28221|Deltaproteobacteria,2MHVY@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
WH3_k127_5747037_3	56780.SYN_00969	8.364e-39	150.0	COG1871@1|root,COG1871@2|Bacteria,1RAWA@1224|Proteobacteria,42QP1@68525|delta/epsilon subdivisions,2WQBY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD1	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
WH3_k127_5747037_2	1304885.AUEY01000002_gene425	1.107e-83	287.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42MR2@68525|delta/epsilon subdivisions,2WKKH@28221|Deltaproteobacteria,2MJG1@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N,Response_reg
WH3_k127_5747037_0	1379270.AUXF01000002_gene1692	8.047e-111	366.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1ZTCI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
WH3_k127_5747414_0	237368.SCABRO_03915	3.574e-218	689.0	COG0459@1|root,COG0459@2|Bacteria,2IXJW@203682|Planctomycetes	203682|Planctomycetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WH3_k127_5747414_2	886293.Sinac_3081	2.436e-32	128.0	COG0234@1|root,COG0234@2|Bacteria,2J0E5@203682|Planctomycetes	203682|Planctomycetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
WH3_k127_5747414_1	452637.Oter_2054	7.892e-97	323.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,3K7T7@414999|Opitutae	414999|Opitutae	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WH3_k127_5748838_0	1237149.C900_00689	6.589e-31	130.0	COG0727@1|root,COG0727@2|Bacteria,4P5VP@976|Bacteroidetes	976|Bacteroidetes	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
WH3_k127_5748838_1	909663.KI867150_gene855	1.197e-14	79.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria,2MQRU@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	PFAM SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
WH3_k127_576282_1	1123508.JH636442_gene4210	8.002e-42	156.0	COG0151@1|root,COG0151@2|Bacteria,2IX58@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
WH3_k127_576282_2	1415775.U729_979	9.258e-28	124.0	COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,24CKX@186801|Clostridia,36GSW@31979|Clostridiaceae	186801|Clostridia	S	Hemerythrin HHE cation binding domain	-	-	-	ko:K09155	-	-	-	-	ko00000	-	-	-	DUF1858,DUF438,Hemerythrin,PAS_10
WH3_k127_576282_0	1408473.JHXO01000004_gene19	1.094e-68	242.0	COG0701@1|root,COG0701@2|Bacteria,4NDUJ@976|Bacteroidetes,2FNF8@200643|Bacteroidia	976|Bacteroidetes	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1,HMA
WH3_k127_5798614_0	1118054.CAGW01000050_gene1204	6.61e-39	160.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,26RNV@186822|Paenibacillaceae	91061|Bacilli	L	ATP-dependent helicase nuclease subunit A	addA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
WH3_k127_579962_1	237368.SCABRO_03329	1.932e-43	165.0	COG1354@1|root,COG1354@2|Bacteria,2IZIR@203682|Planctomycetes	203682|Planctomycetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
WH3_k127_579962_0	644282.Deba_2027	8.286e-113	372.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2WJI2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM aminoacyl-tRNA synthetase class Ib	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
WH3_k127_5812886_0	595460.RRSWK_01472	1.991e-76	269.0	COG0141@1|root,COG0141@2|Bacteria,2IXQ3@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
WH3_k127_5855760_1	926549.KI421517_gene1771	2.945e-08	57.0	COG2207@1|root,COG2207@2|Bacteria,4NKCH@976|Bacteroidetes,47R08@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
WH3_k127_5855760_0	247490.KSU1_C0978	1.252e-131	434.0	COG0550@1|root,COG0550@2|Bacteria,2IY53@203682|Planctomycetes	203682|Planctomycetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
WH3_k127_5877298_0	497964.CfE428DRAFT_4603	1.238e-59	221.0	COG0349@1|root,COG0349@2|Bacteria,46SUU@74201|Verrucomicrobia	74201|Verrucomicrobia	L	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
WH3_k127_5887315_0	264732.Moth_0582	1.598e-70	248.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,42F9T@68295|Thermoanaerobacterales	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
WH3_k127_5889617_3	748449.Halha_2023	3.485e-47	177.0	COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,24DJF@186801|Clostridia,3WBTB@53433|Halanaerobiales	186801|Clostridia	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS19835	UbiA
WH3_k127_5889617_2	1232410.KI421421_gene3889	5.292e-88	305.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2WN09@28221|Deltaproteobacteria,43SVP@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
WH3_k127_5889617_1	1232410.KI421421_gene3889	4.342e-91	314.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2WN09@28221|Deltaproteobacteria,43SVP@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
WH3_k127_5889617_4	886293.Sinac_4186	1.108e-09	71.0	COG1783@1|root,COG1783@2|Bacteria	2|Bacteria	S	DNA packaging	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3,Terminase_6
WH3_k127_5889617_0	583355.Caka_0558	1.883e-252	802.0	COG0657@1|root,COG0657@2|Bacteria,46TU9@74201|Verrucomicrobia,3KA3K@414999|Opitutae	414999|Opitutae	I	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
WH3_k127_5892181_2	1142394.PSMK_15550	6.783e-15	81.0	COG2839@1|root,COG2839@2|Bacteria,2J1KN@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
WH3_k127_5892181_1	583355.Caka_0955	2.115e-113	380.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WH3_k127_5892181_0	1123070.KB899256_gene2238	2.589e-121	395.0	COG1082@1|root,COG1082@2|Bacteria,46TSU@74201|Verrucomicrobia,2IWCW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
WH3_k127_5892181_3	1303518.CCALI_00484	5.781e-09	66.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
WH3_k127_5902921_3	1121422.AUMW01000012_gene2969	2.635e-25	109.0	COG1014@1|root,COG1014@2|Bacteria,1V1DT@1239|Firmicutes,24HIC@186801|Clostridia,261U9@186807|Peptococcaceae	186801|Clostridia	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	iorB	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
WH3_k127_5902921_1	868864.Dester_1081	5.04e-123	408.0	COG1541@1|root,COG1541@2|Bacteria	2|Bacteria	H	phenylacetate-CoA ligase activity	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
WH3_k127_5902921_0	340177.Cag_0403	6.727e-133	435.0	COG4804@1|root,COG4804@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
WH3_k127_5902921_2	1499967.BAYZ01000069_gene1901	2.626e-29	122.0	COG1638@1|root,COG1638@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	-	-	-	-	-	-	-	-	-	DctP
WH3_k127_5946014_2	1123508.JH636440_gene2363	2.435e-10	70.0	COG0177@1|root,COG0177@2|Bacteria,2IZDJ@203682|Planctomycetes	203682|Planctomycetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
WH3_k127_5946014_0	1142394.PSMK_13910	1.32e-112	370.0	COG0040@1|root,COG0040@2|Bacteria,2IXEV@203682|Planctomycetes	203682|Planctomycetes	F	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
WH3_k127_5946014_1	1499967.BAYZ01000068_gene1977	4.279e-85	289.0	COG0217@1|root,COG0217@2|Bacteria,2NNSI@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
WH3_k127_5974811_0	113355.CM001775_gene1664	1.24e-111	405.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G32M@1117|Cyanobacteria	1117|Cyanobacteria	Q	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PPC,VCBS
WH3_k127_6022378_1	477974.Daud_2140	3.386e-14	77.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia,261U6@186807|Peptococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
WH3_k127_6022378_0	521674.Plim_0174	1.892e-167	534.0	COG0056@1|root,COG0056@2|Bacteria,2IXN5@203682|Planctomycetes	203682|Planctomycetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
WH3_k127_60286_0	1379281.AVAG01000014_gene1441	5.477e-76	267.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria,2M7VS@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
WH3_k127_6038482_1	243090.RB2897	1.333e-06	49.0	COG3963@1|root,COG3963@2|Bacteria,2IZWV@203682|Planctomycetes	203682|Planctomycetes	I	Methyltransferase domain	-	-	2.1.1.344	ko:K22309	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
WH3_k127_6038482_0	575540.Isop_1244	4.995e-101	339.0	COG3622@1|root,COG3622@2|Bacteria,2IYNY@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
WH3_k127_6059686_0	760568.Desku_2735	1.306e-84	291.0	COG1163@1|root,COG1163@2|Bacteria,1TSAP@1239|Firmicutes,24EEW@186801|Clostridia,260UT@186807|Peptococcaceae	186801|Clostridia	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
WH3_k127_6085883_1	1121267.JHZL01000004_gene1579	5.172e-29	124.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2YM87@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
WH3_k127_6085883_0	247490.KSU1_D0831	2.482e-49	184.0	COG0287@1|root,COG0287@2|Bacteria,2IZ5K@203682|Planctomycetes	203682|Planctomycetes	E	Prephenate dehydrogenase	-	-	1.3.1.12,1.3.1.43	ko:K00210,ko:K00220,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025,M00040	R00732,R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
WH3_k127_6109454_1	1434325.AZQN01000002_gene951	4.841e-09	61.0	COG4225@1|root,COG4225@2|Bacteria,4NF1N@976|Bacteroidetes,47K76@768503|Cytophagia	976|Bacteroidetes	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
WH3_k127_6109454_0	555088.DealDRAFT_2776	5.833e-38	145.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,42K12@68298|Syntrophomonadaceae	186801|Clostridia	C	TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit	-	-	4.2.1.2,4.2.1.32	ko:K01677,ko:K03779	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
WH3_k127_6114237_0	237368.SCABRO_01083	4.354e-288	892.0	COG0008@1|root,COG0008@2|Bacteria,2IYSE@203682|Planctomycetes	203682|Planctomycetes	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
WH3_k127_6114237_1	756272.Plabr_2090	9.808e-81	276.0	COG4099@1|root,COG4099@2|Bacteria,2IZGT@203682|Planctomycetes	203682|Planctomycetes	P	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Peptidase_S9
WH3_k127_6115238_1	1123400.KB904746_gene1307	3.172e-85	286.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RMKD@1236|Gammaproteobacteria,460BD@72273|Thiotrichales	72273|Thiotrichales	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
WH3_k127_6115238_2	1195236.CTER_0200	3.106e-41	154.0	COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes,24MNA@186801|Clostridia	186801|Clostridia	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
WH3_k127_6115238_0	1449126.JQKL01000047_gene2724	6.669e-255	795.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,26A0R@186813|unclassified Clostridiales	186801|Clostridia	S	Glutamine synthetase type III N terminal	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
WH3_k127_6136006_1	56780.SYN_00905	3.745e-43	160.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,2MQBJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
WH3_k127_6136006_0	1123371.ATXH01000008_gene262	3.811e-53	195.0	COG0337@1|root,COG0337@2|Bacteria,2GGYX@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
WH3_k127_6142804_0	313598.MED152_05185	6.787e-09	58.0	COG2207@1|root,COG2207@2|Bacteria,4NKCH@976|Bacteroidetes,1HYFN@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
WH3_k127_6175321_1	1341181.FLJC2902T_10060	0.0005303	44.0	COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,4NG09@976|Bacteroidetes,1HY3Z@117743|Flavobacteriia,2NU61@237|Flavobacterium	976|Bacteroidetes	O	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
WH3_k127_6175321_0	1123242.JH636438_gene5716	1.417e-139	456.0	COG0104@1|root,COG0104@2|Bacteria,2IWZH@203682|Planctomycetes	203682|Planctomycetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
WH3_k127_6180205_0	404589.Anae109_3561	7.302e-84	291.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2YUQI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WH3_k127_6180205_1	1146883.BLASA_3799	9.962e-55	198.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4ERZ4@85013|Frankiales	201174|Actinobacteria	P	Part of an ABC transporter complex. Responsible for energy coupling to the transport system	cbiO	-	-	ko:K02006,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
WH3_k127_6180876_1	1191523.MROS_0633	3.595e-80	278.0	COG2000@1|root,COG2221@1|root,COG4624@1|root,COG2000@2|Bacteria,COG2221@2|Bacteria,COG4624@2|Bacteria	2|Bacteria	C	iron-sulfur cluster assembly	napF	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10,Fer4_7,PAS
WH3_k127_6180876_0	1121438.JNJA01000012_gene1570	4.324e-92	310.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1MXTC@1224|Proteobacteria,42YW5@68525|delta/epsilon subdivisions,2WUJF@28221|Deltaproteobacteria,2M82R@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,NADH-G_4Fe-4S_3
WH3_k127_6187393_1	756272.Plabr_4556	9.254e-80	273.0	COG1181@1|root,COG1181@2|Bacteria,2IYQF@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
WH3_k127_6187393_0	530564.Psta_3376	3.469e-83	295.0	COG0454@1|root,COG1181@1|root,COG0456@2|Bacteria,COG1181@2|Bacteria,2IZEV@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
WH3_k127_6187393_2	237368.SCABRO_02876	2.727e-16	82.0	2CA4A@1|root,32RQK@2|Bacteria,2J0BM@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4416)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4416
WH3_k127_6197874_2	521674.Plim_3351	1.758e-16	87.0	COG2165@1|root,COG2165@2|Bacteria,2J10X@203682|Planctomycetes	203682|Planctomycetes	U	Pfam:N_methyl_2	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
WH3_k127_6197874_0	278963.ATWD01000001_gene3347	2.879e-61	228.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,F5_F8_type_C,Pectate_lyase_3
WH3_k127_6197874_1	1203611.KB894544_gene2051	3.588e-18	85.0	COG3325@1|root,COG3325@2|Bacteria,4PB9F@976|Bacteroidetes,2G1VG@200643|Bacteroidia,22V99@171550|Rikenellaceae	976|Bacteroidetes	G	Glyco_18	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
WH3_k127_6202267_3	63737.Npun_F0098	6.61e-10	61.0	COG0416@1|root,COG0416@2|Bacteria,1G1CT@1117|Cyanobacteria,1HJJ9@1161|Nostocales	1117|Cyanobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
WH3_k127_6202267_4	1142394.PSMK_17300	1.946e-08	57.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
WH3_k127_6202267_2	344747.PM8797T_08364	8.752e-11	65.0	2DRVG@1|root,33D8Q@2|Bacteria,2J19Z@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6202267_1	237368.SCABRO_01045	4.978e-123	405.0	COG0436@1|root,COG0436@2|Bacteria,2IX5E@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WH3_k127_6202267_0	243090.RB8909	4.905e-151	496.0	COG1283@1|root,COG1283@2|Bacteria,2J2H6@203682|Planctomycetes	203682|Planctomycetes	P	COG1283 Na phosphate symporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
WH3_k127_6206033_0	457570.Nther_0465	1.398e-128	426.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
WH3_k127_6221797_0	1142394.PSMK_24550	7.804e-73	251.0	COG1080@1|root,COG1080@2|Bacteria,2IX08@203682|Planctomycetes	203682|Planctomycetes	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
WH3_k127_6221797_1	760568.Desku_0423	2.126e-13	80.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia,261TK@186807|Peptococcaceae	186801|Clostridia	S	protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
WH3_k127_6221797_2	530564.Psta_2436	1.476e-05	48.0	COG1530@1|root,COG1530@2|Bacteria,2IWSS@203682|Planctomycetes	203682|Planctomycetes	J	TIGRFAM ribonuclease, Rne Rng family	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
WH3_k127_6224252_0	1009370.ALO_15277	1.38e-98	340.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,4H3SW@909932|Negativicutes	909932|Negativicutes	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
WH3_k127_6236003_0	1232437.KL662016_gene1007	1.238e-09	71.0	28J5I@1|root,2Z91C@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
WH3_k127_6258213_1	861299.J421_4334	1.744e-35	140.0	COG1607@1|root,COG1607@2|Bacteria,1ZTQ1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WH3_k127_6258213_0	1408473.JHXO01000001_gene1962	2.714e-64	228.0	COG0667@1|root,COG0667@2|Bacteria,4PPAM@976|Bacteroidetes,2G14T@200643|Bacteroidia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WH3_k127_6262907_0	595460.RRSWK_06791	9.871e-67	235.0	COG1413@1|root,COG3119@1|root,COG1413@2|Bacteria,COG3119@2|Bacteria,2IYFZ@203682|Planctomycetes	203682|Planctomycetes	CP	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	HEAT_2,Sulfatase
WH3_k127_6262907_1	1121423.JONT01000014_gene1235	2.847e-37	145.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,26081@186807|Peptococcaceae	186801|Clostridia	IJM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
WH3_k127_6273920_0	309801.trd_1146	2.578e-23	104.0	COG0363@1|root,COG0363@2|Bacteria,2G6S0@200795|Chloroflexi,27YBD@189775|Thermomicrobia	189775|Thermomicrobia	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
WH3_k127_6273920_1	1331660.L313_2331	1.79e-05	55.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,3NJIK@468|Moraxellaceae	1236|Gammaproteobacteria	D	G-rich domain on putative tyrosine kinase	wzc	GO:0000271,GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016301,GO:0016310,GO:0016462,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0036211,GO:0038083,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046377,GO:0046777,GO:0071704,GO:0071944,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576	-	ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,GNVR,Wzz
WH3_k127_6277313_0	1211844.CBLM010000101_gene293	2.233e-33	138.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,3VR5M@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
WH3_k127_6281319_1	575540.Isop_0532	1.843e-55	202.0	COG0438@1|root,COG0438@2|Bacteria,2IXN1@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WH3_k127_6281319_0	429009.Adeg_1494	1.477e-63	226.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,42FMH@68295|Thermoanaerobacterales	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
WH3_k127_6281319_2	1469607.KK073769_gene6235	2.897e-32	142.0	COG2433@1|root,COG2433@2|Bacteria,1G2BH@1117|Cyanobacteria,1HRA7@1161|Nostocales	1117|Cyanobacteria	S	PFAM transposase IS66	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
WH3_k127_6281319_3	877455.Metbo_0399	1.602e-19	90.0	arCOG03622@1|root,arCOG03622@2157|Archaea,2Y55W@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_630868_0	314230.DSM3645_26996	1.62e-97	325.0	COG0329@1|root,COG0329@2|Bacteria,2IXII@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
WH3_k127_630868_1	118173.KB235914_gene3887	1.631e-72	255.0	COG4912@1|root,COG4912@2|Bacteria,1G63N@1117|Cyanobacteria,1HFFN@1150|Oscillatoriales	1117|Cyanobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
WH3_k127_6312089_0	1168034.FH5T_01555	3.096e-98	334.0	COG0348@1|root,COG0348@2|Bacteria,4NPVD@976|Bacteroidetes,2FTEY@200643|Bacteroidia	976|Bacteroidetes	C	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
WH3_k127_6322178_0	644282.Deba_0414	7.621e-16	82.0	COG1143@1|root,COG2006@1|root,COG1143@2|Bacteria,COG2006@2|Bacteria,1RABP@1224|Proteobacteria,42QQA@68525|delta/epsilon subdivisions,2WMRX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4
WH3_k127_6330341_0	886293.Sinac_5880	4.12e-38	153.0	COG1269@1|root,COG1269@2|Bacteria,2IZU8@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
WH3_k127_6330341_1	1142394.PSMK_22340	3.065e-12	76.0	COG1269@1|root,COG1269@2|Bacteria,2IZU8@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
WH3_k127_6331784_0	1121430.JMLG01000006_gene1748	6.111e-56	199.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,25E7B@186801|Clostridia,260CN@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WH3_k127_6338931_0	886293.Sinac_3249	3.828e-128	417.0	COG0209@1|root,COG0209@2|Bacteria,2IX3H@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
WH3_k127_6363737_0	926692.AZYG01000038_gene1075	3.831e-124	420.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3WA67@53433|Halanaerobiales	186801|Clostridia	S	PFAM ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WH3_k127_63650_1	317619.ANKN01000161_gene297	9.513e-56	201.0	COG2084@1|root,COG2084@2|Bacteria,1G1GH@1117|Cyanobacteria,1MKTN@1212|Prochloraceae	1117|Cyanobacteria	I	Alternative locus ID	mmsB	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
WH3_k127_63650_0	869213.JCM21142_93473	8.284e-114	372.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	Thioredoxin_3,URO-D
WH3_k127_6369050_1	1232453.BAIF02000004_gene1569	5.229e-101	332.0	28MXM@1|root,2Z8AT@2|Bacteria,1V0XI@1239|Firmicutes,24DIS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6369050_0	313628.LNTAR_07951	9.308e-186	595.0	COG4146@1|root,COG4146@2|Bacteria	2|Bacteria	S	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
WH3_k127_6369050_2	180332.JTGN01000003_gene1800	1.677e-11	66.0	COG3254@1|root,COG3254@2|Bacteria,1V1XT@1239|Firmicutes,24NE4@186801|Clostridia	186801|Clostridia	S	L-rhamnose mutarotase	-	-	-	-	-	-	-	-	-	-	-	-	rhaM
WH3_k127_6370084_0	946077.W5A_11996	7.617e-37	141.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,1HYIB@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
WH3_k127_6370084_1	1123242.JH636434_gene4709	7.075e-29	120.0	COG0724@1|root,COG0724@2|Bacteria,2IZPY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
WH3_k127_6373393_0	383372.Rcas_3343	8.32e-30	122.0	COG2084@1|root,COG2084@2|Bacteria,2G6B3@200795|Chloroflexi,376B1@32061|Chloroflexia	32061|Chloroflexia	I	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
WH3_k127_6373393_1	13684.SNOT_13807	0.0003668	48.0	COG5260@1|root,KOG2277@2759|Eukaryota,38EW5@33154|Opisthokonta,3NXI7@4751|Fungi,3QPXA@4890|Ascomycota,1ZYD7@147541|Dothideomycetes,4KCMC@92860|Pleosporales	4751|Fungi	D	Cid1 family poly A polymerase	-	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0004652,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016073,GO:0016074,GO:0016180,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0031124,GO:0031126,GO:0034470,GO:0034641,GO:0034660,GO:0043144,GO:0043170,GO:0043628,GO:0043629,GO:0043631,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070566,GO:0071050,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	-	-	-	-	-	-	-	-	-	NTP_transf_2,PAP_assoc
WH3_k127_6380809_0	1396141.BATP01000003_gene4934	2.13e-58	231.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
WH3_k127_6380809_1	1122609.AUGT01000008_gene2868	9.099e-17	96.0	COG0366@1|root,COG0515@1|root,COG2133@1|root,COG3227@1|root,COG4733@1|root,COG0366@2|Bacteria,COG0515@2|Bacteria,COG2133@2|Bacteria,COG3227@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.3	ko:K01178,ko:K14645,ko:K18546	ko00500,ko01100,ko02024,map00500,map01100,map02024	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH15	-	Alpha-amylase,GSDH,He_PIG,PKD,Pro_Al_protease,SLH,Trypsin,fn3
WH3_k127_6400813_1	472759.Nhal_1160	7.544e-35	139.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1X09F@135613|Chromatiales	135613|Chromatiales	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WH3_k127_6400813_0	1142394.PSMK_00010	2.458e-58	209.0	COG0593@1|root,COG0593@2|Bacteria,2IWXU@203682|Planctomycetes	203682|Planctomycetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
WH3_k127_641042_0	638303.Thal_0306	9.623e-54	203.0	COG0486@1|root,COG0486@2|Bacteria,2G3TR@200783|Aquificae	200783|Aquificae	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
WH3_k127_6429017_0	575540.Isop_3045	8.131e-49	179.0	COG0457@1|root,COG0457@2|Bacteria,2IZQ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
WH3_k127_6429017_1	575540.Isop_2462	1.345e-45	170.0	COG3437@1|root,COG3437@2|Bacteria,2J516@203682|Planctomycetes	203682|Planctomycetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WH3_k127_6429017_2	48698.ENSPFOP00000012715	1.678e-09	70.0	COG0457@1|root,COG3914@1|root,KOG1124@2759|Eukaryota,KOG4626@2759|Eukaryota,38EM5@33154|Opisthokonta,3BC3N@33208|Metazoa,3CWN6@33213|Bilateria,4870C@7711|Chordata,48X60@7742|Vertebrata,49R5B@7898|Actinopterygii	33208|Metazoa	GOT	O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1	OGT	GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252	2.4.1.255	ko:K09667	ko00514,ko04931,map00514,map04931	-	R09304,R09676	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03036	-	GT41	-	Glyco_transf_41,TPR_1,TPR_11,TPR_2,TPR_8
WH3_k127_6430436_1	1288494.EBAPG3_3000	1.308e-32	135.0	2EFX2@1|root,339PA@2|Bacteria,1NGKD@1224|Proteobacteria,2VY14@28216|Betaproteobacteria,374HM@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
WH3_k127_6430436_0	1232410.KI421412_gene435	5.747e-79	271.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42PI3@68525|delta/epsilon subdivisions,2WJN3@28221|Deltaproteobacteria,43TSZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
WH3_k127_6431564_0	335541.Swol_1956	2.797e-53	200.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,42KD3@68298|Syntrophomonadaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
WH3_k127_6445027_2	1049564.TevJSym_aa00830	2.253e-34	139.0	COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,1S5B7@1236|Gammaproteobacteria,1J71P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
WH3_k127_6445027_0	243231.GSU1391	1.147e-73	252.0	COG2184@1|root,COG2184@2|Bacteria,1RAVF@1224|Proteobacteria,42TM9@68525|delta/epsilon subdivisions,2WUZ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
WH3_k127_6445027_1	398767.Glov_2564	2.707e-36	140.0	COG1396@1|root,COG1396@2|Bacteria,1N3BI@1224|Proteobacteria,42XZE@68525|delta/epsilon subdivisions,2WSYW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
WH3_k127_6458229_1	1027292.HMPREF9372_2415	0.0009685	48.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,26GUJ@186818|Planococcaceae	91061|Bacilli	O	Trypsin	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WH3_k127_6462574_0	1121406.JAEX01000011_gene2062	7.238e-123	406.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,42RHV@68525|delta/epsilon subdivisions,2WNH5@28221|Deltaproteobacteria,2MA5W@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Nickel-dependent hydrogenase	hyhL	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
WH3_k127_6465393_0	595460.RRSWK_00734	2.509e-61	234.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WH3_k127_6465393_1	243090.RB9196	1.468e-47	192.0	COG1793@1|root,COG1793@2|Bacteria,2J0I2@203682|Planctomycetes	203682|Planctomycetes	L	secreted glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
WH3_k127_6465393_2	1179773.BN6_30840	1.459e-15	91.0	COG1881@1|root,COG2133@1|root,COG1881@2|Bacteria,COG2133@2|Bacteria,2GISM@201174|Actinobacteria,4E1H5@85010|Pseudonocardiales	201174|Actinobacteria	G	Carbohydrate binding module (family 35)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_35,CBM_6,GSDH,PBP,fn3
WH3_k127_6465393_3	575540.Isop_0679	5.444e-10	63.0	COG0828@1|root,COG0828@2|Bacteria,2J1A6@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
WH3_k127_6487802_1	449447.MAE_20400	7.621e-17	83.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,CBM_4_9,DUF3466,FG-GAP_2
WH3_k127_6487802_0	314230.DSM3645_18836	1.001e-43	164.0	COG0780@1|root,COG0780@2|Bacteria,2J07W@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
WH3_k127_6487802_3	314230.DSM3645_12506	0.0009972	48.0	COG5523@1|root,COG5523@2|Bacteria,2J0JS@203682|Planctomycetes	203682|Planctomycetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6487802_2	313628.LNTAR_13872	1.738e-08	62.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K16919	ko02010,map02010	M00254,M00584	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
WH3_k127_6508668_0	247490.KSU1_C0411	6.478e-61	220.0	COG1418@1|root,COG1418@2|Bacteria,2IX35@203682|Planctomycetes	203682|Planctomycetes	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
WH3_k127_6513717_1	563192.HMPREF0179_03454	5.254e-09	61.0	arCOG05185@1|root,2Z9G9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6513717_0	247490.KSU1_C1563	5.005e-82	280.0	COG1674@1|root,COG1674@2|Bacteria,2IXHF@203682|Planctomycetes	203682|Planctomycetes	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WH3_k127_6533511_1	794903.OPIT5_04965	2.414e-20	94.0	2E5IJ@1|root,3309Y@2|Bacteria,46SYV@74201|Verrucomicrobia,3K87A@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6533511_0	865861.AZSU01000002_gene2813	7.423e-69	248.0	COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,24BEY@186801|Clostridia,36J2T@31979|Clostridiaceae	186801|Clostridia	E	TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase	-	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WH3_k127_6542439_1	404589.Anae109_1500	8.163e-59	212.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2YUZZ@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WH3_k127_6542439_0	56780.SYN_02383	1.462e-314	983.0	COG0574@1|root,COG0574@2|Bacteria,1N38V@1224|Proteobacteria,42MWC@68525|delta/epsilon subdivisions,2WKAZ@28221|Deltaproteobacteria,2MR7X@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
WH3_k127_6547685_1	1121403.AUCV01000063_gene4186	1.311e-31	129.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,42P8N@68525|delta/epsilon subdivisions,2WNVW@28221|Deltaproteobacteria,2MJJY@213118|Desulfobacterales	28221|Deltaproteobacteria	HP	PFAM ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
WH3_k127_6547685_0	697281.Mahau_0754	2.791e-64	230.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,42FK7@68295|Thermoanaerobacterales	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	yvrB	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
WH3_k127_6573998_1	1111479.AXAR01000002_gene1806	0.0003	49.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,4HBTY@91061|Bacilli,279TP@186823|Alicyclobacillaceae	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WH3_k127_6573998_0	1121403.AUCV01000012_gene4045	1.561e-155	501.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,2MHY8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
WH3_k127_6588719_4	1280949.HAD_02625	2.845e-23	102.0	COG1695@1|root,COG1695@2|Bacteria,1N0PH@1224|Proteobacteria,2UBD4@28211|Alphaproteobacteria,440IU@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
WH3_k127_6588719_3	1345695.CLSA_c37610	2.239e-34	153.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,36HDP@31979|Clostridiaceae	186801|Clostridia	KT	Peptidase, M56	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	NAGPA,Peptidase_M56
WH3_k127_6588719_5	1321778.HMPREF1982_02439	2.247e-15	91.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,26950@186813|unclassified Clostridiales	186801|Clostridia	KT	Psort location CytoplasmicMembrane, score	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	NAGPA,Peptidase_M56
WH3_k127_6588719_1	1502770.JQMG01000001_gene2384	8.874e-78	275.0	COG5563@1|root,COG5563@2|Bacteria,1PVXD@1224|Proteobacteria,2WBJI@28216|Betaproteobacteria,2KP0H@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
WH3_k127_6588719_0	316067.Geob_2141	6.521e-126	415.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42MFI@68525|delta/epsilon subdivisions,2WKXD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WH3_k127_6588719_2	1203606.HMPREF1526_00389	2.111e-37	147.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,36DSA@31979|Clostridiaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
WH3_k127_6601300_4	857293.CAAU_2467	4.369e-20	92.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,36I28@31979|Clostridiaceae	186801|Clostridia	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
WH3_k127_6601300_1	247490.KSU1_C0568	6.515e-84	289.0	COG0502@1|root,COG0502@2|Bacteria,2IXTG@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
WH3_k127_6601300_3	756272.Plabr_2327	1.079e-23	107.0	2E296@1|root,32XEW@2|Bacteria,2J070@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6601300_0	1313304.CALK_0657	1.509e-101	346.0	COG0124@1|root,COG0124@2|Bacteria	2|Bacteria	J	histidine-tRNA ligase activity	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
WH3_k127_6601300_2	344747.PM8797T_31830	1.002e-29	123.0	COG0727@1|root,COG0727@2|Bacteria,2IZU5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
WH3_k127_6606571_0	639030.JHVA01000001_gene2962	2.584e-18	90.0	COG2159@1|root,COG2159@2|Bacteria,3Y7XT@57723|Acidobacteria,2JNXE@204432|Acidobacteriia	204432|Acidobacteriia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
WH3_k127_6606571_1	1055815.AYYA01000013_gene1519	6.725e-17	89.0	COG4859@1|root,COG4859@2|Bacteria	2|Bacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2185,DUF3239,DUF4241
WH3_k127_6637031_1	1499967.BAYZ01000177_gene5729	1.244e-66	234.0	COG0207@1|root,COG0207@2|Bacteria	2|Bacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
WH3_k127_6637031_0	903818.KI912268_gene1338	4.315e-68	242.0	COG0275@1|root,COG0275@2|Bacteria,3Y31S@57723|Acidobacteria	57723|Acidobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_5
WH3_k127_6640163_1	682795.AciX8_0687	1.68e-05	47.0	COG0618@1|root,COG0618@2|Bacteria,3Y2GZ@57723|Acidobacteria,2JI0W@204432|Acidobacteriia	204432|Acidobacteriia	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WH3_k127_6640163_0	926569.ANT_31570	8.275e-44	173.0	COG2199@1|root,COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,2G8CK@200795|Chloroflexi	200795|Chloroflexi	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
WH3_k127_664660_0	1142394.PSMK_05510	2.994e-65	240.0	COG0169@1|root,COG0710@1|root,COG0169@2|Bacteria,COG0710@2|Bacteria,2IXKU@203682|Planctomycetes	203682|Planctomycetes	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroD	-	1.1.1.25,4.2.1.10	ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
WH3_k127_6658954_1	1120950.KB892747_gene3742	4.623e-30	130.0	COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria,4DQ6M@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
WH3_k127_6658954_0	742735.HMPREF9467_03653	3.825e-35	136.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,21XK5@1506553|Lachnoclostridium	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
WH3_k127_6667074_0	344747.PM8797T_24306	8.979e-142	467.0	COG1199@1|root,COG1199@2|Bacteria,2IX82@203682|Planctomycetes	203682|Planctomycetes	KL	helicase	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
WH3_k127_6670447_1	1142394.PSMK_28990	6.346e-56	200.0	COG0201@1|root,COG0201@2|Bacteria,2IXN6@203682|Planctomycetes	203682|Planctomycetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
WH3_k127_6670447_0	1458462.JNLK01000001_gene977	2.613e-64	227.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,27IND@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
WH3_k127_6670447_2	886293.Sinac_0465	6.769e-49	180.0	COG0024@1|root,COG0024@2|Bacteria,2IXPX@203682|Planctomycetes	203682|Planctomycetes	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WH3_k127_6673323_0	1041930.Mtc_0309	7.788e-21	107.0	arCOG04998@1|root,arCOG08112@1|root,arCOG04998@2157|Archaea,arCOG08112@2157|Archaea,2Y7YH@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6699167_1	1163617.SCD_n00721	4.592e-13	72.0	2DR1A@1|root,339RT@2|Bacteria,1NGFB@1224|Proteobacteria,2VXU8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3096)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3096
WH3_k127_6699167_0	1198452.Jab_2c21390	2.463e-120	403.0	COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2VJ6Y@28216|Betaproteobacteria	28216|Betaproteobacteria	U	TIGRFAM filamentous haemagglutinin family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Haemagg_act
WH3_k127_6704493_0	886293.Sinac_5953	7.591e-75	262.0	COG0621@1|root,COG0621@2|Bacteria,2IX1E@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
WH3_k127_6704493_1	768671.ThimaDRAFT_0738	1.446e-06	53.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria,1WWNT@135613|Chromatiales	135613|Chromatiales	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
WH3_k127_6707662_0	314230.DSM3645_20022	6.274e-47	174.0	COG0106@1|root,COG0106@2|Bacteria,2IYYG@203682|Planctomycetes	203682|Planctomycetes	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
WH3_k127_6707662_1	1280946.HY29_01910	1.334e-07	61.0	COG3768@1|root,COG3768@2|Bacteria,1NNZU@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF697
WH3_k127_671743_1	192952.MM_1136	0.000132	48.0	COG5563@1|root,arCOG03499@1|root,arCOG03499@2157|Archaea,arCOG03501@2157|Archaea	2157|Archaea	S	Disaggregatase related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Disaggr_assoc,Disaggr_repeat,PKD
WH3_k127_671743_0	450851.PHZ_c2281	1.772e-08	65.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2TRXN@28211|Alphaproteobacteria,2KEY2@204458|Caulobacterales	204458|Caulobacterales	M	Penicillin-binding protein 2	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
WH3_k127_6748075_1	234267.Acid_2265	3.931e-166	528.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
WH3_k127_6748075_0	234267.Acid_2264	1.605e-185	594.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
WH3_k127_6758509_2	457396.CSBG_03413	3.53e-63	228.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,36ERG@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
WH3_k127_6758509_0	886293.Sinac_6460	1.893e-166	540.0	COG2804@1|root,COG2804@2|Bacteria,2IXSA@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
WH3_k127_6758509_1	756272.Plabr_2546	6.084e-154	492.0	COG2805@1|root,COG2805@2|Bacteria,2IXRP@203682|Planctomycetes	203682|Planctomycetes	NU	COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WH3_k127_6764959_1	1122963.AUHB01000001_gene365	2.085e-09	61.0	COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria,36YRF@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Exonuclease VII small subunit	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
WH3_k127_6764959_0	500635.MITSMUL_03532	2.045e-91	319.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4H31X@909932|Negativicutes	909932|Negativicutes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
WH3_k127_6765924_0	265072.Mfla_2234	7.415e-196	632.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,2KKHN@206350|Nitrosomonadales	206350|Nitrosomonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WH3_k127_6775149_0	643648.Slip_1543	4.311e-117	382.0	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia,42KH6@68298|Syntrophomonadaceae	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
WH3_k127_6775149_1	926567.TheveDRAFT_1557	2.771e-40	154.0	COG1343@1|root,COG1343@2|Bacteria,3TBB1@508458|Synergistetes	508458|Synergistetes	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	-	-	-	-	-	-	-	-	-	CRISPR_Cas2
WH3_k127_6777458_0	237368.SCABRO_03724	1.237e-117	390.0	COG1389@1|root,COG1389@2|Bacteria,2J2A8@203682|Planctomycetes	203682|Planctomycetes	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,Topo-VIb_trans
WH3_k127_6777458_1	1121423.JONT01000015_gene1289	1.694e-36	145.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,260G0@186807|Peptococcaceae	186801|Clostridia	E	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
WH3_k127_6792851_2	240016.ABIZ01000001_gene5451	1.22e-05	50.0	COG3250@1|root,COG5492@1|root,COG3250@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Laminin_G_3,Lyase_8,Lyase_8_C,Sulfatase
WH3_k127_6792851_0	886293.Sinac_6056	2.58e-35	138.0	COG1259@1|root,COG1259@2|Bacteria,2IZNE@203682|Planctomycetes	203682|Planctomycetes	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
WH3_k127_6792851_1	1158345.JNLL01000001_gene1302	4.483e-20	98.0	COG0597@1|root,COG0597@2|Bacteria,2G47U@200783|Aquificae	200783|Aquificae	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
WH3_k127_6792851_3	159749.K0T3F3	8.374e-05	51.0	COG0013@1|root,KOG1155@2759|Eukaryota,2XASB@2836|Bacillariophyta	2836|Bacillariophyta	DO	Anaphase promoting complex subunit 8 / Cdc23	-	-	-	ko:K03355	ko04110,ko04111,ko04113,ko04114,ko04120,ko04914,ko05166,map04110,map04111,map04113,map04114,map04120,map04914,map05166	M00389	-	-	ko00000,ko00001,ko00002,ko03036,ko04121	-	-	-	ANAPC8,TPR_7,TPR_8
WH3_k127_6805223_0	1499967.BAYZ01000174_gene5829	2.81e-80	275.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	Thioredoxin_3,URO-D
WH3_k127_6805223_1	1499967.BAYZ01000056_gene4870	7.747e-40	160.0	COG0523@1|root,COG0523@2|Bacteria	2|Bacteria	P	cobalamin synthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
WH3_k127_6810303_1	1089552.KI911559_gene2017	4.069e-28	116.0	COG2963@1|root,COG2963@2|Bacteria,1RGZ5@1224|Proteobacteria,2UAIS@28211|Alphaproteobacteria,2JT7W@204441|Rhodospirillales	204441|Rhodospirillales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
WH3_k127_6810303_0	313628.LNTAR_22879	2.605e-152	492.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	ko:K06889,ko:K07214	-	-	-	-	ko00000	-	-	-	AXE1,Abhydrolase_1,Esterase,Lipase_GDSL_2,Peptidase_S9
WH3_k127_6837629_1	338966.Ppro_0559	2.096e-43	165.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,42RII@68525|delta/epsilon subdivisions,2WNS9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM VacJ family lipoprotein	-	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
WH3_k127_6837629_0	96561.Dole_2278	2.335e-107	356.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MMIR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
WH3_k127_6841323_0	1172188.KB911820_gene2847	1.812e-07	63.0	COG3567@1|root,COG3567@2|Bacteria,2H48H@201174|Actinobacteria	201174|Actinobacteria	S	Phage portal protein, SPP1 Gp6-like	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
WH3_k127_6846349_0	247490.KSU1_B0246	3.408e-158	507.0	COG0459@1|root,COG0459@2|Bacteria,2IWZS@203682|Planctomycetes	203682|Planctomycetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WH3_k127_6846349_5	509191.AEDB02000019_gene4509	3.348e-35	141.0	2E13Z@1|root,32WJ8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6846349_4	439235.Dalk_3938	7.64e-48	176.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,42TKH@68525|delta/epsilon subdivisions,2WQBD@28221|Deltaproteobacteria,2MKEM@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
WH3_k127_6846349_2	697303.Thewi_2202	1.487e-78	273.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,42EKM@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WH3_k127_6846349_3	1499967.BAYZ01000194_gene3127	1.975e-78	269.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	ywhC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
WH3_k127_6846349_6	768672.Desfe_0119	3.435e-17	89.0	arCOG04797@1|root,arCOG04797@2157|Archaea,2XS23@28889|Crenarchaeota	28889|Crenarchaeota	S	retrograde transport, endosome to Golgi	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6846349_7	1379698.RBG1_1C00001G1719	1.981e-08	60.0	COG2189@1|root,COG2189@2|Bacteria,2NP0F@2323|unclassified Bacteria	2|Bacteria	L	PFAM DNA methylase N-4 N-6	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
WH3_k127_6846349_1	1313421.JHBV01000027_gene1794	7.55e-99	324.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1INN5@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
WH3_k127_6874796_0	429009.Adeg_1231	1.541e-80	277.0	COG0374@1|root,COG0374@2|Bacteria,1TQMW@1239|Firmicutes,248BB@186801|Clostridia,42FVY@68295|Thermoanaerobacterales	186801|Clostridia	C	hydrogenase large subunit	-	-	1.12.5.1,1.12.99.6	ko:K05922,ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
WH3_k127_6874796_1	525897.Dbac_1970	1.338e-14	74.0	COG1740@1|root,COG1740@2|Bacteria,1PW7V@1224|Proteobacteria,43B3H@68525|delta/epsilon subdivisions,2X6HA@28221|Deltaproteobacteria,2M9TA@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	small subunit	hysB	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
WH3_k127_6890347_1	1121440.AUMA01000015_gene1817	7.488e-135	445.0	COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,42QJC@68525|delta/epsilon subdivisions,2WPI2@28221|Deltaproteobacteria,2M9VY@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_10,TPR_16,TPR_19,TPR_4,TPR_8
WH3_k127_6890347_2	869209.Tresu_0044	7.189e-37	150.0	COG0564@1|root,COG0564@2|Bacteria,2J5NV@203691|Spirochaetes	203691|Spirochaetes	J	Pseudouridine synthase	-	-	5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29	ko:K06177,ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
WH3_k127_6890347_0	1366050.N234_35010	2.166e-143	460.0	29MQ2@1|root,308MT@2|Bacteria,1REUR@1224|Proteobacteria,2VXQA@28216|Betaproteobacteria,1K3YT@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6920794_0	1168034.FH5T_15580	1.668e-170	560.0	COG5434@1|root,COG5492@1|root,COG5434@2|Bacteria,COG5492@2|Bacteria,4NIYD@976|Bacteroidetes,2FRQ9@200643|Bacteroidia	976|Bacteroidetes	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Pectate_lyase_3
WH3_k127_6926583_0	1121918.ARWE01000001_gene3119	1.251e-123	406.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WJ1M@28221|Deltaproteobacteria,43S7W@69541|Desulfuromonadales	68525|delta/epsilon subdivisions	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
WH3_k127_6928470_0	243090.RB5847	2.823e-54	194.0	COG0503@1|root,COG0503@2|Bacteria,2IZ9H@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
WH3_k127_6933410_0	584708.Apau_2422	1.621e-134	436.0	COG0369@1|root,COG1151@2|Bacteria,3TA79@508458|Synergistetes	508458|Synergistetes	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
WH3_k127_6960605_0	1151292.QEW_1361	5.031e-111	371.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
WH3_k127_6960605_1	932678.THERU_06950	7.84e-07	53.0	COG0325@1|root,COG0325@2|Bacteria,2G3XD@200783|Aquificae	200783|Aquificae	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
WH3_k127_696370_0	344747.PM8797T_07432	7.523e-38	148.0	COG0642@1|root,COG2205@2|Bacteria,2IXRW@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
WH3_k127_696370_1	1408439.JHXW01000012_gene889	1.738e-15	86.0	COG1396@1|root,COG1974@1|root,COG1396@2|Bacteria,COG1974@2|Bacteria,3799F@32066|Fusobacteria	32066|Fusobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_S24
WH3_k127_6967628_1	1142394.PSMK_10920	3.413e-07	53.0	COG0060@1|root,COG0060@2|Bacteria,2IWX2@203682|Planctomycetes	203682|Planctomycetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
WH3_k127_6967628_0	1158294.JOMI01000007_gene530	4.48e-11	71.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	2.3.1.82	ko:K03825,ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
WH3_k127_6970730_0	344747.PM8797T_09364	9.592e-148	477.0	COG2804@1|root,COG2804@2|Bacteria,2IX4I@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
WH3_k127_6976053_1	237368.SCABRO_03847	8.474e-35	140.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	iamC	-	-	ko:K02067,ko:K06192	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
WH3_k127_6976053_0	338963.Pcar_2750	3.771e-93	313.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2WKHW@28221|Deltaproteobacteria,43UPV@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
WH3_k127_6976053_2	396588.Tgr7_1494	4.441e-17	83.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1S0WJ@1236|Gammaproteobacteria,1WWFB@135613|Chromatiales	135613|Chromatiales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS_2
WH3_k127_697735_0	574087.Acear_2112	1.597e-121	398.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
WH3_k127_697735_1	338963.Pcar_2463	1.641e-25	108.0	COG0655@1|root,COG0655@2|Bacteria,1RKK7@1224|Proteobacteria,42T1X@68525|delta/epsilon subdivisions,2WPCQ@28221|Deltaproteobacteria,43V03@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
WH3_k127_6982160_1	580340.Tlie_1297	3.175e-76	261.0	COG0409@1|root,COG0409@2|Bacteria,3T9X1@508458|Synergistetes	508458|Synergistetes	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
WH3_k127_6982160_0	1187851.A33M_3105	7.002e-86	293.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,2TQSJ@28211|Alphaproteobacteria,3FDZU@34008|Rhodovulum	28211|Alphaproteobacteria	O	AIR synthase related protein, C-terminal domain	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
WH3_k127_6985507_1	1392493.JIAB01000001_gene77	2.58e-17	84.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,27MA4@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Lumazine binding domain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
WH3_k127_6985507_0	1142394.PSMK_11860	9.956e-105	349.0	COG1995@1|root,COG1995@2|Bacteria,2IYEZ@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the PdxA family	pdxA	-	1.1.1.408,1.1.1.409	ko:K22024	-	-	-	-	ko00000,ko01000	-	-	-	PdxA
WH3_k127_7002088_1	1033732.CAHI01000006_gene2268	3.318e-30	128.0	COG1451@1|root,COG1451@2|Bacteria,4NNY6@976|Bacteroidetes,2FPFA@200643|Bacteroidia	976|Bacteroidetes	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
WH3_k127_7002088_0	945713.IALB_2034	9.342e-35	137.0	COG0733@1|root,COG0733@2|Bacteria	2|Bacteria	S	neurotransmitter:sodium symporter activity	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
WH3_k127_7028456_0	247490.KSU1_C0408	4.016e-230	733.0	COG0060@1|root,COG0060@2|Bacteria,2IWX2@203682|Planctomycetes	203682|Planctomycetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
WH3_k127_7041530_0	760192.Halhy_1128	8.752e-43	168.0	COG3209@1|root,COG3209@2|Bacteria,4NFUE@976|Bacteroidetes,1INSI@117747|Sphingobacteriia	976|Bacteroidetes	M	COG3209 Rhs family protein	rhsA	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
WH3_k127_7070360_1	1142394.PSMK_15060	2.064e-09	63.0	COG1215@1|root,COG1215@2|Bacteria,2IZ8G@203682|Planctomycetes	203682|Planctomycetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_21
WH3_k127_7070360_2	247490.KSU1_C0977	5.991e-09	69.0	COG0760@1|root,COG0760@2|Bacteria,2J38Q@203682|Planctomycetes	203682|Planctomycetes	O	SurA N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7070360_0	744872.Spica_0095	4.126e-100	334.0	COG1373@1|root,COG1373@2|Bacteria,2J5MK@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WH3_k127_7142636_2	243090.RB7685	8.665e-06	53.0	COG2165@1|root,COG2165@2|Bacteria,2J50F@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
WH3_k127_7142636_1	1142394.PSMK_20230	2.413e-116	387.0	COG1459@1|root,COG1459@2|Bacteria,2IX2A@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway component PulF	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
WH3_k127_7142636_0	1142394.PSMK_20220	1.232e-186	593.0	COG2804@1|root,COG2804@2|Bacteria,2IXGK@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
WH3_k127_7145336_3	370438.PTH_1997	1.239e-06	52.0	arCOG09742@1|root,2ZBGR@2|Bacteria,1V0RW@1239|Firmicutes,24AYH@186801|Clostridia,263KV@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7145336_2	370438.PTH_0741	3.493e-29	122.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,2621R@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised P-loop hydrolase UPF0079	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
WH3_k127_7145336_1	1210884.HG799466_gene12310	1.576e-55	207.0	COG0611@1|root,COG0611@2|Bacteria,2IZG9@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WH3_k127_7145336_0	247490.KSU1_D0616	6.174e-102	341.0	COG0165@1|root,COG0165@2|Bacteria,2IWV5@203682|Planctomycetes	203682|Planctomycetes	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
WH3_k127_7153149_0	497964.CfE428DRAFT_5300	8.568e-160	515.0	COG0673@1|root,COG0673@2|Bacteria,46S8U@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WH3_k127_7153149_2	1303518.CCALI_00378	6.95e-11	72.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
WH3_k127_7153149_1	880073.Calab_0640	1.617e-103	345.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	-	-	-	-	-	-	-	-	-	SSF
WH3_k127_7175082_0	1047013.AQSP01000140_gene2513	1.353e-67	243.0	COG1322@1|root,COG1322@2|Bacteria,2NPXU@2323|unclassified Bacteria	2|Bacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
WH3_k127_7175082_1	313612.L8106_21674	2.851e-33	141.0	COG0398@1|root,COG0398@2|Bacteria,1G3R9@1117|Cyanobacteria,1H8VH@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
WH3_k127_7239672_1	1123376.AUIU01000011_gene942	3.917e-25	107.0	COG0853@1|root,COG0853@2|Bacteria,3J0Q2@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
WH3_k127_7239672_0	575540.Isop_0883	1.043e-39	160.0	COG0682@1|root,COG0682@2|Bacteria,2IZQ2@203682|Planctomycetes	203682|Planctomycetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT,PDZ
WH3_k127_7279397_1	339670.Bamb_3421	3.037e-12	80.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,2VIVD@28216|Betaproteobacteria,1JZXV@119060|Burkholderiaceae	28216|Betaproteobacteria	U	Belongs to the GSP D family	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
WH3_k127_7279397_0	237368.SCABRO_01614	1.982e-21	95.0	COG2231@1|root,COG2231@2|Bacteria,2IZ9A@203682|Planctomycetes	203682|Planctomycetes	L	endonuclease III	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
WH3_k127_7285601_1	1303518.CCALI_01287	2.422e-78	265.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00162,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
WH3_k127_7285601_0	1499967.BAYZ01000154_gene1465	7.942e-195	614.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	fucI	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0008736,GO:0008790,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0042802,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0046372,GO:0071704,GO:1901575	5.3.1.25,5.3.1.3	ko:K01818	ko00051,ko01120,map00051,map01120	-	R03163	RC00434	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c30720,ic_1306.c3371	Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2
WH3_k127_7294430_1	1121396.KB892902_gene2288	1.703e-29	125.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PH8@68525|delta/epsilon subdivisions,2WKUF@28221|Deltaproteobacteria,2MPS1@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PocR,Response_reg
WH3_k127_7294430_0	575540.Isop_3169	1.753e-70	246.0	COG0029@1|root,COG0029@2|Bacteria,2IY30@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
WH3_k127_7315837_1	926569.ANT_06890	6.704e-16	83.0	2ECEX@1|root,336D4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7315837_2	595460.RRSWK_04742	7.443e-08	57.0	2DGM2@1|root,2ZWFW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7315837_0	857293.CAAU_2260	7.671e-114	381.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,36DVT@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
WH3_k127_7366300_0	1304875.JAFZ01000002_gene119	7.617e-54	198.0	COG1706@1|root,COG1706@2|Bacteria,3TA0P@508458|Synergistetes	508458|Synergistetes	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
WH3_k127_7366300_1	338963.Pcar_1154	1.022e-19	94.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,42MJW@68525|delta/epsilon subdivisions,2WNRD@28221|Deltaproteobacteria,43UYZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
WH3_k127_7380069_2	1463857.JOFZ01000008_gene394	1.152e-28	123.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria	201174|Actinobacteria	IQ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	tcmK	-	2.3.1.235,2.3.1.260	ko:K05551	ko00253,ko01056,ko01130,map00253,map01056,map01130	M00778	R06635,R06637,R06641,R06643,R06644,R06645,R09258,R09259,R10960,R11516	RC00004,RC00039,RC02545,RC02728,RC02729,RC02931,RC02932,RC02947	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WH3_k127_7380069_0	756272.Plabr_2931	6.757e-137	448.0	COG0304@1|root,COG0304@2|Bacteria,2IX8X@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WH3_k127_7380069_1	706587.Desti_5519	1.44e-30	126.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,2MQ90@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
WH3_k127_741008_0	563192.HMPREF0179_03201	6.048e-132	430.0	COG1449@1|root,COG1449@2|Bacteria,1R8JX@1224|Proteobacteria,42QA5@68525|delta/epsilon subdivisions,2WMM5@28221|Deltaproteobacteria,2M9GJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
WH3_k127_741008_1	56780.SYN_00881	1.355e-66	232.0	COG0297@1|root,COG0297@2|Bacteria,1R6U0@1224|Proteobacteria,42Q1W@68525|delta/epsilon subdivisions,2WJXW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Starch synthase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
WH3_k127_7412083_2	224324.aq_1286	0.0009893	51.0	COG3156@1|root,COG3156@2|Bacteria,2G4SA@200783|Aquificae	200783|Aquificae	U	Type II secretion system (T2SS), protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
WH3_k127_7412083_0	1142394.PSMK_24340	3.163e-112	376.0	COG0515@1|root,COG0515@2|Bacteria,2IYFB@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WH3_k127_7412083_1	309799.DICTH_0775	3.401e-05	48.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
WH3_k127_7432582_0	573413.Spirs_2934	3.915e-129	422.0	COG0263@1|root,COG0263@2|Bacteria,2J6GB@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
WH3_k127_746033_1	1054213.HMPREF9946_03247	6.424e-08	62.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,2UB4D@28211|Alphaproteobacteria,2JWYI@204441|Rhodospirillales	204441|Rhodospirillales	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
WH3_k127_746033_0	690850.Desaf_2633	5.586e-19	92.0	COG3009@1|root,COG3009@2|Bacteria,1N9IG@1224|Proteobacteria,42VAV@68525|delta/epsilon subdivisions,2WS0E@28221|Deltaproteobacteria,2MBBH@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
WH3_k127_746033_2	177437.HRM2_49270	0.0003381	48.0	COG1463@1|root,COG1463@2|Bacteria,1MYEF@1224|Proteobacteria,42SPY@68525|delta/epsilon subdivisions,2WKD0@28221|Deltaproteobacteria,2MICD@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
WH3_k127_7468845_0	562970.Btus_1022	8.664e-150	481.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H9ZG@91061|Bacilli,2798V@186823|Alicyclobacillaceae	91061|Bacilli	EG	Dehydratase family	ilvD	-	4.2.1.9	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ILVD_EDD
WH3_k127_7468845_2	1304866.K413DRAFT_3616	1.201e-41	166.0	COG0613@1|root,COG0613@2|Bacteria,1V6HN@1239|Firmicutes,24DQ6@186801|Clostridia,36WM4@31979|Clostridiaceae	186801|Clostridia	S	DNA polymerase alpha chain like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7468845_3	641491.DND132_0231	4.595e-29	121.0	COG1661@1|root,COG1661@2|Bacteria,1RIUJ@1224|Proteobacteria,42SC0@68525|delta/epsilon subdivisions,2WPPG@28221|Deltaproteobacteria,2MB8Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF296)	-	-	-	-	-	-	-	-	-	-	-	-	DUF296
WH3_k127_7468845_1	545695.TREAZ_2765	4.229e-97	328.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
WH3_k127_7497752_0	867903.ThesuDRAFT_01664	9.986e-103	351.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3WCXE@538999|Clostridiales incertae sedis	186801|Clostridia	M	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WH3_k127_7497752_1	335541.Swol_0220	7.283e-27	113.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2,NTase_sub_bind,UPF0158
WH3_k127_7514883_0	290318.Cvib_1132	1.244e-119	388.0	COG3943@1|root,COG3943@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
WH3_k127_7529069_1	243231.GSU0742	4.632e-106	351.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,42MG7@68525|delta/epsilon subdivisions,2WIRA@28221|Deltaproteobacteria,43TR1@69541|Desulfuromonadales	28221|Deltaproteobacteria	CP	Proton-conducting membrane transporter	ehrD	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
WH3_k127_7529069_0	316067.Geob_1700	8.238e-201	637.0	COG3261@1|root,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,42NJH@68525|delta/epsilon subdivisions,2WJ6J@28221|Deltaproteobacteria,43SVB@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	ehrL	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
WH3_k127_7529069_2	316067.Geob_1699	3.581e-99	329.0	COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,42NH3@68525|delta/epsilon subdivisions,2WJX8@28221|Deltaproteobacteria,43T9P@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7,Oxidored_q6
WH3_k127_7529069_3	444158.MmarC6_0363	1.613e-05	51.0	arCOG02806@1|root,arCOG02806@2157|Archaea,2XWDA@28890|Euryarchaeota,23RU6@183939|Methanococci	183939|Methanococci	P	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
WH3_k127_7531061_0	595460.RRSWK_03181	1.658e-45	180.0	COG0544@1|root,COG0544@2|Bacteria,2IXGD@203682|Planctomycetes	203682|Planctomycetes	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
WH3_k127_7531061_1	1123508.JH636440_gene2373	4.031e-40	164.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,2J0ZD@203682|Planctomycetes	203682|Planctomycetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
WH3_k127_7531061_2	439235.Dalk_2288	3.183e-14	79.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42R71@68525|delta/epsilon subdivisions,2WMW5@28221|Deltaproteobacteria,2MPW6@213118|Desulfobacterales	28221|Deltaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,RHS,RHS_repeat,Transglut_core
WH3_k127_7578328_1	96561.Dole_1786	5.538e-13	75.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	ydcH	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
WH3_k127_7578328_0	234267.Acid_2413	2.449e-58	212.0	COG3212@1|root,COG3212@2|Bacteria	2|Bacteria	T	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
WH3_k127_7689444_0	1121403.AUCV01000018_gene3190	2.144e-109	362.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42QVZ@68525|delta/epsilon subdivisions,2WMVN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
WH3_k127_7689444_1	338966.Ppro_3363	1.163e-104	350.0	COG3829@1|root,COG3829@2|Bacteria,1MXSB@1224|Proteobacteria,42PHW@68525|delta/epsilon subdivisions,2WJSS@28221|Deltaproteobacteria,43TCI@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
WH3_k127_7690291_0	1223545.GS4_16_00050	5.009e-34	151.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4GCH6@85026|Gordoniaceae	201174|Actinobacteria	DM	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,ParA,Wzz
WH3_k127_7690291_1	886293.Sinac_2489	1.029e-24	108.0	COG1269@1|root,COG1269@2|Bacteria,2IZU8@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
WH3_k127_7696123_1	595460.RRSWK_03196	1.747e-52	192.0	COG3250@1|root,COG3250@2|Bacteria,2J22V@203682|Planctomycetes	2|Bacteria	G	Beta galactosidase small chain	lacZ	GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0032991,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575,GO:1902494	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
WH3_k127_7696123_2	990073.ATHU01000001_gene318	4.488e-11	68.0	COG3937@1|root,COG3937@2|Bacteria,1NM7V@1224|Proteobacteria,42WSS@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	granule-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
WH3_k127_7696123_0	1121918.ARWE01000001_gene2051	1.745e-112	380.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,43S4A@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
WH3_k127_7696278_2	742735.HMPREF9467_03038	1.645e-06	61.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,21XPP@1506553|Lachnoclostridium	186801|Clostridia	E	Belongs to the peptidase S8 family	aprX	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
WH3_k127_7696278_0	1294143.H681_14790	1.691e-108	368.0	COG2067@1|root,COG2067@2|Bacteria,1R3SS@1224|Proteobacteria,1S0X2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
WH3_k127_7696278_1	1532558.JL39_15420	3.06e-32	129.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2TTXG@28211|Alphaproteobacteria,4B9AV@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
WH3_k127_7720586_1	1142394.PSMK_25970	1.975e-64	229.0	COG1459@1|root,COG1459@2|Bacteria,2IYHA@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
WH3_k127_7720586_0	1142394.PSMK_25980	7.363e-131	428.0	COG2805@1|root,COG2805@2|Bacteria,2IXRP@203682|Planctomycetes	203682|Planctomycetes	NU	COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WH3_k127_7720586_2	665952.HMPREF1015_03153	4.608e-18	87.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,1ZD5J@1386|Bacillus	91061|Bacilli	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilB	-	-	ko:K02243,ko:K02652	-	M00429	-	-	ko00000,ko00002,ko02035,ko02044	3.A.14.1,3.A.15.2	-	-	T2SSE,T2SSE_N
WH3_k127_7722511_0	521674.Plim_1374	1.825e-139	462.0	COG1198@1|root,COG1198@2|Bacteria,2IY1F@203682|Planctomycetes	203682|Planctomycetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
WH3_k127_7722511_1	485915.Dret_1651	5.301e-35	137.0	COG0748@1|root,COG0748@2|Bacteria,1N2JV@1224|Proteobacteria,42TYW@68525|delta/epsilon subdivisions,2WQEM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
WH3_k127_7722511_3	1449126.JQKL01000002_gene1557	4.554e-14	74.0	COG0298@1|root,COG0298@2|Bacteria,1VFE0@1239|Firmicutes,24UXU@186801|Clostridia	186801|Clostridia	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
WH3_k127_7722511_2	696281.Desru_2366	5.579e-16	79.0	COG0409@1|root,COG0409@2|Bacteria,1TPM7@1239|Firmicutes,248EX@186801|Clostridia,2605Y@186807|Peptococcaceae	186801|Clostridia	O	Hydrogenase expression formation protein hypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
WH3_k127_773201_2	1076550.LH22_09905	1.514e-10	63.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,3W1R7@53335|Pantoea	1236|Gammaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WH3_k127_773201_0	143224.JQMD01000002_gene1701	4.618e-168	542.0	COG3119@1|root,COG3119@2|Bacteria,4NE6V@976|Bacteroidetes,1HZ00@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
WH3_k127_773201_1	926549.KI421517_gene1530	1.467e-76	263.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,47JNX@768503|Cytophagia	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WH3_k127_7743369_2	314230.DSM3645_25427	9.336e-65	229.0	COG0657@1|root,COG0657@2|Bacteria,2IY98@203682|Planctomycetes	203682|Planctomycetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
WH3_k127_7743369_5	314230.DSM3645_25427	1.755e-23	101.0	COG0657@1|root,COG0657@2|Bacteria,2IY98@203682|Planctomycetes	203682|Planctomycetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
WH3_k127_7743369_6	228405.HNE_0478	2.22e-12	70.0	2DEJE@1|root,2ZN82@2|Bacteria,1PB33@1224|Proteobacteria,2UY1B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7743369_1	443143.GM18_1937	1.641e-71	254.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria,43SCM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
WH3_k127_7743369_3	1047013.AQSP01000110_gene68	8.088e-64	226.0	COG0569@1|root,COG0569@2|Bacteria	2|Bacteria	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_C
WH3_k127_7743369_0	247490.KSU1_C0203	1.653e-115	382.0	COG0598@1|root,COG0598@2|Bacteria,2IX61@203682|Planctomycetes	203682|Planctomycetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
WH3_k127_7743369_4	1254432.SCE1572_23190	8.477e-51	187.0	COG2908@1|root,COG2908@2|Bacteria	2|Bacteria	M	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
WH3_k127_7744540_3	589865.DaAHT2_0861	7.18e-62	226.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria,2MI3C@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
WH3_k127_7744540_0	886293.Sinac_5597	1.177e-107	363.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,2IZ4S@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108,4.2.1.59	ko:K02535,ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
WH3_k127_7744540_4	530564.Psta_1866	2.509e-54	200.0	COG1043@1|root,COG1043@2|Bacteria,2IZR6@203682|Planctomycetes	203682|Planctomycetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
WH3_k127_7744540_2	237368.SCABRO_01915	1.048e-73	261.0	COG0673@1|root,COG0673@2|Bacteria,2IXAX@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WH3_k127_7744540_1	319225.Plut_1169	8.252e-75	257.0	COG0722@1|root,COG0722@2|Bacteria,1FDG4@1090|Chlorobi	1090|Chlorobi	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
WH3_k127_777511_0	247490.KSU1_D0781	1.559e-70	265.0	COG0534@1|root,COG0534@2|Bacteria,2IXGS@203682|Planctomycetes	203682|Planctomycetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
WH3_k127_777511_2	1007103.AFHW01000096_gene3283	0.0003663	51.0	COG0697@1|root,COG0697@2|Bacteria,1TSE2@1239|Firmicutes,4HBD2@91061|Bacilli,26S0T@186822|Paenibacillaceae	91061|Bacilli	EG	Transporter	yoaV3	-	-	-	-	-	-	-	-	-	-	-	EamA
WH3_k127_777511_1	304371.MCP_1489	5.982e-45	169.0	COG1032@1|root,arCOG04984@2157|Archaea,2XUS3@28890|Euryarchaeota,2N97H@224756|Methanomicrobia	224756|Methanomicrobia	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
WH3_k127_7780900_2	84531.JMTZ01000039_gene534	1.525e-44	165.0	COG2273@1|root,COG2273@2|Bacteria,1N5RS@1224|Proteobacteria,1RSMD@1236|Gammaproteobacteria,1X5MJ@135614|Xanthomonadales	135614|Xanthomonadales	G	Glycosyl hydrolases family 16	lamA	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
WH3_k127_7780900_1	865937.Gilli_1966	7.616e-69	268.0	COG1749@1|root,COG5295@1|root,COG1749@2|Bacteria,COG5295@2|Bacteria,4NTUT@976|Bacteroidetes	976|Bacteroidetes	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4082
WH3_k127_7780900_0	1209072.ALBT01000007_gene2717	2.993e-182	620.0	COG2273@1|root,COG3291@1|root,COG2273@2|Bacteria,COG3291@2|Bacteria,1N5RS@1224|Proteobacteria,1RSMD@1236|Gammaproteobacteria,1FHVH@10|Cellvibrio	1236|Gammaproteobacteria	G	Glycosyl hydrolase catalytic core	lamA	-	-	-	-	-	-	-	-	-	-	-	CBM_6,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_cc,PKD
WH3_k127_7787273_4	886293.Sinac_6057	9.904e-17	81.0	COG0525@1|root,COG0525@2|Bacteria,2IWU4@203682|Planctomycetes	203682|Planctomycetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WH3_k127_7787273_0	1232410.KI421416_gene2649	2.507e-243	767.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42MJE@68525|delta/epsilon subdivisions,2WK5T@28221|Deltaproteobacteria,43TCV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	aplA	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	iAF987.Gmet_0739	SSF
WH3_k127_7787273_2	913865.DOT_4540	8.436e-25	106.0	2DQ0U@1|root,3349F@2|Bacteria	2|Bacteria	S	Protein of unknown function, DUF485	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
WH3_k127_7787273_3	748449.Halha_2303	1.819e-24	106.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,3WAWT@53433|Halanaerobiales	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
WH3_k127_7787273_1	247490.KSU1_D0964	8.552e-175	561.0	COG0154@1|root,COG0154@2|Bacteria,2IXW5@203682|Planctomycetes	203682|Planctomycetes	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WH3_k127_7795944_3	1267535.KB906767_gene3407	6.484e-15	77.0	COG0697@1|root,2Z7ID@2|Bacteria,3Y8N8@57723|Acidobacteria,2JNIX@204432|Acidobacteriia	204432|Acidobacteriia	EG	L-rhamnose-proton symport protein (RhaT)	-	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
WH3_k127_7795944_2	1122927.KB895414_gene4824	1.736e-42	158.0	COG3254@1|root,COG3254@2|Bacteria,1V1XT@1239|Firmicutes	1239|Firmicutes	S	L-rhamnose mutarotase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2,rhaM
WH3_k127_7795944_1	1142394.PSMK_14770	1.165e-63	232.0	COG1560@1|root,COG1560@2|Bacteria,2IY7N@203682|Planctomycetes	203682|Planctomycetes	M	Lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
WH3_k127_7795944_0	243090.RB6537	1.879e-149	479.0	COG2017@1|root,COG2017@2|Bacteria,2IWRW@203682|Planctomycetes	203682|Planctomycetes	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
WH3_k127_7811368_2	555779.Dthio_PD1648	8.974e-07	54.0	COG0594@1|root,COG0594@2|Bacteria,1NGQJ@1224|Proteobacteria,42VBC@68525|delta/epsilon subdivisions,2WRF0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
WH3_k127_7811368_0	646529.Desaci_3952	3.315e-09	61.0	COG0789@1|root,COG0789@2|Bacteria,1VB7I@1239|Firmicutes,24RCE@186801|Clostridia,266I7@186807|Peptococcaceae	186801|Clostridia	K	regulatory protein	-	-	-	ko:K11923,ko:K13638	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
WH3_k127_7811368_1	1247024.JRLH01000007_gene1846	3.276e-07	59.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	mlaD	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008289,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
WH3_k127_7822294_0	443144.GM21_4085	9.708e-157	505.0	COG1344@1|root,COG1344@2|Bacteria,1MXC4@1224|Proteobacteria	1224|Proteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF1522,Flagellin_C,Flagellin_N
WH3_k127_7827637_1	1265505.ATUG01000003_gene442	1.706e-63	227.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,2MJPN@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
WH3_k127_7827637_0	530564.Psta_4054	6.704e-124	405.0	COG2876@1|root,COG2876@2|Bacteria,2IWU9@203682|Planctomycetes	203682|Planctomycetes	E	phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
WH3_k127_7845851_3	592015.HMPREF1705_01721	3.626e-07	54.0	28XQZ@1|root,2ZJMK@2|Bacteria,3TCGY@508458|Synergistetes	508458|Synergistetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7845851_0	679926.Mpet_0215	1.13e-33	132.0	COG1669@1|root,arCOG01206@2157|Archaea	2157|Archaea	M	PFAM DNA polymerase beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
WH3_k127_7845851_1	65393.PCC7424_0997	2.465e-31	126.0	COG2361@1|root,COG2361@2|Bacteria,1G7XA@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG2361 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
WH3_k127_7845851_2	638302.HMPREF0908_0004	3.353e-15	79.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H201@909932|Negativicutes	909932|Negativicutes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WH3_k127_7863429_0	1116472.MGMO_57c00290	2.037e-63	231.0	COG2327@1|root,COG2327@2|Bacteria,1MXWP@1224|Proteobacteria,1RRDB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	biosynthesis protein	wcaK	-	-	ko:K16710	-	-	-	-	ko00000	-	-	iECSF_1327.ECSF_1934,iSBO_1134.SBO_0872	PS_pyruv_trans
WH3_k127_7880687_1	1218173.BALCAV_0216470	3.558e-147	476.0	COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,4HB93@91061|Bacilli,1ZAP4@1386|Bacillus	91061|Bacilli	P	Major facilitator superfamily	oxlT	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
WH3_k127_7880687_2	1142394.PSMK_19550	1.111e-116	389.0	COG2262@1|root,COG2262@2|Bacteria,2IXH5@203682|Planctomycetes	203682|Planctomycetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
WH3_k127_7880687_3	234831.PSM_B0631	7.281e-51	186.0	COG2930@1|root,COG2930@2|Bacteria,1RCH3@1224|Proteobacteria,1S2SV@1236|Gammaproteobacteria,2Q2AW@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Las17-binding protein actin regulator	VPA0371	-	-	-	-	-	-	-	-	-	-	-	Ysc84
WH3_k127_7880687_0	1168034.FH5T_15275	7.785e-224	702.0	COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes,2FMMW@200643|Bacteroidia	976|Bacteroidetes	G	glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
WH3_k127_7880687_4	1499967.BAYZ01000166_gene6617	7.257e-18	82.0	COG0362@1|root,COG0362@2|Bacteria,2NS40@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
WH3_k127_7881748_2	883.DvMF_3036	5.207e-34	140.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WKBG@28221|Deltaproteobacteria,2M7VH@213115|Desulfovibrionales	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_7
WH3_k127_7881748_1	745411.B3C1_00435	5.253e-51	193.0	COG0421@1|root,COG0421@2|Bacteria,1N1PJ@1224|Proteobacteria,1SY8T@1236|Gammaproteobacteria,1JA5K@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
WH3_k127_7881748_3	156578.ATW7_00800	7.137e-32	132.0	COG4262@1|root,COG4262@2|Bacteria,1RFZS@1224|Proteobacteria,1S1NP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7881748_0	247490.KSU1_D0450	2.869e-74	261.0	COG0593@1|root,COG0593@2|Bacteria,2IWXU@203682|Planctomycetes	203682|Planctomycetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
WH3_k127_7929243_0	1142394.PSMK_00390	2.001e-106	353.0	COG0552@1|root,COG0552@2|Bacteria,2IXAG@203682|Planctomycetes	203682|Planctomycetes	D	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
WH3_k127_7960857_0	1313421.JHBV01000023_gene5134	1.654e-60	226.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,1IS94@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
WH3_k127_7961585_0	530564.Psta_2421	3.569e-198	632.0	COG0488@1|root,COG0488@2|Bacteria,2IWXR@203682|Planctomycetes	203682|Planctomycetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
WH3_k127_7961585_1	545694.TREPR_3642	1.95e-116	381.0	COG1208@1|root,COG1208@2|Bacteria,2J5V0@203691|Spirochaetes	203691|Spirochaetes	JM	Domain of unknown function (DUF4954)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4954
WH3_k127_7986931_0	595460.RRSWK_06189	2.797e-115	381.0	COG1894@1|root,COG1894@2|Bacteria,2IXJ8@203682|Planctomycetes	203682|Planctomycetes	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
WH3_k127_8017709_0	41431.PCC8801_3885	1.942e-35	156.0	COG2931@1|root,COG3291@1|root,COG4254@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria,COG4254@2|Bacteria,1G3EW@1117|Cyanobacteria,3KKMT@43988|Cyanothece	1117|Cyanobacteria	Q	G8	-	-	-	-	-	-	-	-	-	-	-	-	G8,HemolysinCabind,Laminin_G_3,PKD
WH3_k127_8017709_1	1168034.FH5T_07240	1.253e-08	68.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,CBM9_1,CBM_4_9,Cellulase,DUF285,Glyco_hydro_10,SLH,VCBS,fn3
WH3_k127_8044837_0	316067.Geob_0375	8.928e-306	951.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria,43TSH@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	por	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
WH3_k127_8046108_0	203119.Cthe_2269	2.703e-45	171.0	COG1394@1|root,COG1394@2|Bacteria,1TQ1Y@1239|Firmicutes,247TC@186801|Clostridia,3WHIG@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
WH3_k127_8054881_0	1321778.HMPREF1982_02247	1.891e-175	566.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,267T0@186813|unclassified Clostridiales	186801|Clostridia	KL	HELICc2	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
WH3_k127_8067279_0	575540.Isop_2527	1.516e-13	81.0	COG3064@1|root,COG3064@2|Bacteria,2IYZ5@203682|Planctomycetes	203682|Planctomycetes	M	SpoIVB peptidase S55	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
WH3_k127_8067279_1	1340493.JNIF01000003_gene2343	3.276e-07	59.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,VCBS
WH3_k127_8083591_1	526222.Desal_1351	1.4e-27	116.0	COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,42PD2@68525|delta/epsilon subdivisions,2WJIK@28221|Deltaproteobacteria,2M7WH@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SEC-C,SPASM
WH3_k127_8083591_0	1232410.KI421414_gene2877	3.665e-171	563.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2WJEB@28221|Deltaproteobacteria,43TVP@69541|Desulfuromonadales	28221|Deltaproteobacteria	GM	Polysaccharide biosynthesis protein CapD	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
WH3_k127_8083591_2	247490.KSU1_B0240	4.448e-07	58.0	2CFWI@1|root,32S2N@2|Bacteria,2J08K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8090197_2	1499967.BAYZ01000057_gene4702	6.466e-07	52.0	COG0019@1|root,COG0019@2|Bacteria	2|Bacteria	E	diaminopimelate decarboxylase activity	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
WH3_k127_8090197_0	382464.ABSI01000014_gene1428	1.012e-28	119.0	2CCSR@1|root,32RWC@2|Bacteria,46XSI@74201|Verrucomicrobia,2IWGZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WH3_k127_8090197_1	2325.TKV_c01400	3.362e-22	103.0	COG1670@1|root,COG1670@2|Bacteria,1V1G8@1239|Firmicutes,24G73@186801|Clostridia,42G9C@68295|Thermoanaerobacterales	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WH3_k127_8126585_0	1117318.PRUB_22556	1.848e-39	166.0	28UR3@1|root,2ZGVE@2|Bacteria,1RB70@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8126585_1	382464.ABSI01000011_gene2441	1.447e-15	90.0	COG1572@1|root,COG3210@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,46XF9@74201|Verrucomicrobia,2IVRE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	QU	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8175602_0	871968.DESME_10210	5.243e-88	293.0	COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,26012@186807|Peptococcaceae	186801|Clostridia	C	ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WH3_k127_8175602_1	445970.ALIPUT_00386	7.743e-13	72.0	COG1146@1|root,COG1146@2|Bacteria,4NV91@976|Bacteroidetes,2FTXT@200643|Bacteroidia,22VMY@171550|Rikenellaceae	976|Bacteroidetes	C	4Fe-4S binding domain	oorD	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_21,Fer4_4
WH3_k127_8175602_2	313596.RB2501_02000	8.426e-10	60.0	COG1482@1|root,COG1482@2|Bacteria,4NF9A@976|Bacteroidetes,1HXBP@117743|Flavobacteriia	976|Bacteroidetes	G	isomerase	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
WH3_k127_8178646_0	575540.Isop_2443	5.927e-80	280.0	COG1061@1|root,COG1061@2|Bacteria,2J0ES@203682|Planctomycetes	203682|Planctomycetes	L	COGs COG1061 DNA or RNA helicase of superfamily II	-	-	-	ko:K19789	-	-	-	-	ko00000,ko03400	-	-	-	Helicase_C,ResIII
WH3_k127_8200602_0	292459.STH1821	2.657e-71	248.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WH3_k127_8236705_1	886293.Sinac_2434	9.181e-06	51.0	COG2730@1|root,COG3250@1|root,COG2730@2|Bacteria,COG3250@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
WH3_k127_8236705_0	886293.Sinac_2434	2.998e-06	49.0	COG2730@1|root,COG3250@1|root,COG2730@2|Bacteria,COG3250@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
WH3_k127_8243256_0	706587.Desti_0451	1.888e-32	139.0	COG0784@1|root,COG3437@1|root,COG3829@1|root,COG5002@1|root,COG0784@2|Bacteria,COG3437@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2X756@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,PocR,Response_reg
WH3_k127_8258544_0	247490.KSU1_C0825	2.217e-55	199.0	COG0533@1|root,COG0533@2|Bacteria,2IXJP@203682|Planctomycetes	203682|Planctomycetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WH3_k127_8258544_1	536227.CcarbDRAFT_5355	5.18e-41	156.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,36F1K@31979|Clostridiaceae	186801|Clostridia	S	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
WH3_k127_8275565_1	1254432.SCE1572_08105	1.902e-51	188.0	COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,42SM7@68525|delta/epsilon subdivisions,2WP5E@28221|Deltaproteobacteria,2YYGZ@29|Myxococcales	28221|Deltaproteobacteria	G	Converts alpha-aldose to the beta-anomer	galM2	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
WH3_k127_8275565_0	1379698.RBG1_1C00001G0812	5.809e-72	249.0	COG0177@1|root,COG0177@2|Bacteria,2NPBI@2323|unclassified Bacteria	2|Bacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
WH3_k127_8275565_2	102129.Lepto7375DRAFT_1517	2.049e-30	127.0	COG0561@1|root,COG0561@2|Bacteria,1GDI4@1117|Cyanobacteria	1117|Cyanobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WH3_k127_8308585_0	404380.Gbem_0096	6.585e-174	549.0	COG0516@1|root,COG0516@2|Bacteria,1MUJM@1224|Proteobacteria	1224|Proteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaC	GO:0003674,GO:0003824,GO:0003920,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015949,GO:0015950,GO:0015951,GO:0016491,GO:0016651,GO:0016657,GO:0019637,GO:0019693,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.1.1.205,1.7.1.7	ko:K00088,ko:K00364	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R01134,R08240	RC00143,RC00457,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iEC042_1314.EC042_0103,iECIAI39_1322.ECIAI39_0105,iECUMN_1333.ECUMN_0102	IMPDH
WH3_k127_8314755_1	1142394.PSMK_15560	1.261e-15	79.0	COG1277@1|root,COG1277@2|Bacteria,2IYX5@203682|Planctomycetes	203682|Planctomycetes	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
WH3_k127_8314755_0	1142394.PSMK_15610	2.52e-53	205.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WH3_k127_8343757_0	886293.Sinac_4560	7.592e-42	169.0	COG0582@1|root,COG0582@2|Bacteria,2J0YT@203682|Planctomycetes	203682|Planctomycetes	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
WH3_k127_8347120_0	391623.TERMP_00208	2.807e-167	534.0	COG1274@1|root,arCOG05865@2157|Archaea,2XUU1@28890|Euryarchaeota,24380@183968|Thermococci	183968|Thermococci	C	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
WH3_k127_8358509_0	1089553.Tph_c20550	1.284e-72	256.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,42FM5@68295|Thermoanaerobacterales	186801|Clostridia	EH	Anthranilate synthase component I, N terminal region	pabB	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
WH3_k127_8358509_1	1209989.TepiRe1_1775	1.033e-55	201.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,42G6X@68295|Thermoanaerobacterales	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WH3_k127_8380923_0	1123037.AUDE01000030_gene3204	7.047e-108	357.0	COG0286@1|root,COG0286@2|Bacteria,4NGGB@976|Bacteroidetes,1HYHR@117743|Flavobacteriia	976|Bacteroidetes	V	type I restriction-modification system, methyltransferase subunit	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
WH3_k127_8380976_0	477641.MODMU_4711	6.834e-87	299.0	COG0836@1|root,COG0836@2|Bacteria,2GIRM@201174|Actinobacteria	201174|Actinobacteria	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
WH3_k127_8380976_1	394503.Ccel_1010	2.004e-59	209.0	COG4154@1|root,COG4154@2|Bacteria,1V402@1239|Firmicutes,24FU7@186801|Clostridia,36IDM@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the RbsD FucU family	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
WH3_k127_8393894_0	247633.GP2143_05970	1.021e-116	389.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WH3_k127_8393894_1	373903.Hore_04240	3.079e-106	355.0	COG2273@1|root,COG5309@1|root,COG2273@2|Bacteria,COG5309@2|Bacteria,1TR5U@1239|Firmicutes,248GW@186801|Clostridia,3WB6W@53433|Halanaerobiales	186801|Clostridia	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Glyco_hydro_16
WH3_k127_8432898_1	1042877.GQS_03530	0.0001641	52.0	COG1418@1|root,arCOG01860@2157|Archaea,2XT54@28890|Euryarchaeota,24358@183968|Thermococci	183968|Thermococci	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
WH3_k127_8432898_0	1211815.CBYP010000040_gene2555	2.483e-41	158.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4ESMC@85013|Frankiales	201174|Actinobacteria	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WH3_k127_8437849_1	177437.HRM2_21730	9.722e-22	98.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WM33@28221|Deltaproteobacteria,2MIM6@213118|Desulfobacterales	28221|Deltaproteobacteria	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
WH3_k127_8437849_0	1142394.PSMK_18500	1.152e-56	208.0	COG1624@1|root,COG1624@2|Bacteria,2IZSP@203682|Planctomycetes	203682|Planctomycetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
WH3_k127_8441762_0	521674.Plim_1347	6.806e-100	333.0	COG0343@1|root,COG0343@2|Bacteria,2IWXI@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
WH3_k127_8441762_2	1142394.PSMK_23640	2.461e-11	70.0	COG1862@1|root,COG1862@2|Bacteria	2|Bacteria	U	protein transport	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
WH3_k127_8441762_1	1142394.PSMK_23630	2.88e-95	344.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2IYCQ@203682|Planctomycetes	203682|Planctomycetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
WH3_k127_8443476_0	247490.KSU1_D0522	2.541e-183	586.0	COG0215@1|root,COG0215@2|Bacteria,2IX9C@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
WH3_k127_8443476_1	469618.FVAG_00037	3.24e-12	71.0	29IC7@1|root,3059E@2|Bacteria,37AAR@32066|Fusobacteria	32066|Fusobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8487183_2	1304872.JAGC01000009_gene601	6.395e-12	70.0	COG1959@1|root,COG1959@2|Bacteria,1MZ1C@1224|Proteobacteria,42SPF@68525|delta/epsilon subdivisions,2WPVC@28221|Deltaproteobacteria,2MBCY@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
WH3_k127_8487183_1	338966.Ppro_2801	1.047e-30	124.0	COG1917@1|root,COG1917@2|Bacteria,1RJX2@1224|Proteobacteria,42TVK@68525|delta/epsilon subdivisions,2WQ2T@28221|Deltaproteobacteria,43SQH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WH3_k127_8487183_0	592015.HMPREF1705_02230	1.188e-34	136.0	COG0369@1|root,COG1151@2|Bacteria,3TA79@508458|Synergistetes	508458|Synergistetes	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
WH3_k127_849116_0	1423780.LOT_0464	2.621e-22	106.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,3F3JG@33958|Lactobacillaceae	91061|Bacilli	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
WH3_k127_8516060_0	468059.AUHA01000002_gene566	4.191e-59	210.0	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,1IQEJ@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
WH3_k127_8516060_2	452637.Oter_1358	6.391e-39	149.0	COG3254@1|root,COG3254@2|Bacteria,46XUW@74201|Verrucomicrobia,3K8BE@414999|Opitutae	414999|Opitutae	J	Involved in the anomeric conversion of L-rhamnose	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
WH3_k127_8516060_1	1121104.AQXH01000001_gene1014	1.985e-45	172.0	COG1785@1|root,COG1785@2|Bacteria,4NG3D@976|Bacteroidetes,1IPXF@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
WH3_k127_8516617_4	1121918.ARWE01000001_gene1445	2.04e-79	269.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,43S5G@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
WH3_k127_8516617_3	933262.AXAM01000002_gene535	8.564e-114	378.0	COG0502@1|root,COG0502@2|Bacteria,1MXK0@1224|Proteobacteria,42M3U@68525|delta/epsilon subdivisions,2WJQ6@28221|Deltaproteobacteria,2MHKZ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Biotin and Thiamin Synthesis associated	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
WH3_k127_8516617_0	313628.LNTAR_19547	4.86e-190	602.0	COG1593@1|root,COG1593@2|Bacteria	2|Bacteria	G	mannitol 2-dehydrogenase activity	dctM	-	-	-	-	-	-	-	-	-	-	-	DctM
WH3_k127_8516617_7	595460.RRSWK_04372	4.458e-40	156.0	COG3090@1|root,COG3090@2|Bacteria	2|Bacteria	G	Trap-type c4-dicarboxylate transport system, small permease component	-	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
WH3_k127_8516617_1	595460.RRSWK_04373	1.349e-138	448.0	COG1638@1|root,COG1638@2|Bacteria,2J4SE@203682|Planctomycetes	203682|Planctomycetes	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
WH3_k127_8516617_5	690850.Desaf_0637	2.452e-70	248.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria,2M8MK@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
WH3_k127_8516617_2	1121468.AUBR01000020_gene2853	4.482e-126	411.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,42EWI@68295|Thermoanaerobacterales	186801|Clostridia	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
WH3_k127_8516617_6	247490.KSU1_D0721	7.082e-56	205.0	COG1187@1|root,COG1187@2|Bacteria,2IYUS@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WH3_k127_8516617_8	1499967.BAYZ01000176_gene5632	8.57e-08	53.0	COG0693@1|root,COG0693@2|Bacteria,2NRMH@2323|unclassified Bacteria	2|Bacteria	S	DJ-1/PfpI family	thiJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006517,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009100,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019538,GO:0022613,GO:0030091,GO:0033554,GO:0034599,GO:0036211,GO:0036524,GO:0036525,GO:0042026,GO:0042221,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564	2.7.11.1,3.5.1.124	ko:K03152,ko:K05520,ko:K05687,ko:K12132	ko05012,map05012	-	-	-	ko00000,ko00001,ko01000,ko01001,ko01002,ko04147	-	-	-	DJ-1_PfpI
WH3_k127_8535231_1	1118060.CAGZ01000024_gene600	9.505e-56	203.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4CUIV@84998|Coriobacteriia	84998|Coriobacteriia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
WH3_k127_8535231_0	1121413.JMKT01000012_gene537	1.224e-78	273.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,42TGK@68525|delta/epsilon subdivisions,2WNGS@28221|Deltaproteobacteria,2MGTS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
WH3_k127_8535231_2	96561.Dole_1704	3.258e-25	119.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8535231_3	1410618.JNKI01000055_gene1717	9.095e-11	71.0	COG1596@1|root,COG1596@2|Bacteria,1V3F4@1239|Firmicutes,4H47M@909932|Negativicutes	909932|Negativicutes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
WH3_k127_8535231_4	1392489.JPOL01000002_gene1680	6.92e-10	67.0	COG1404@1|root,COG2755@1|root,COG1404@2|Bacteria,COG2755@2|Bacteria,4NJGD@976|Bacteroidetes,1I10M@117743|Flavobacteriia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
WH3_k127_8557636_0	240016.ABIZ01000001_gene5154	2.18e-43	175.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WH3_k127_8584117_1	1057002.KB905370_gene2949	5.231e-40	161.0	2E29A@1|root,32XEZ@2|Bacteria,1RDST@1224|Proteobacteria,2U86I@28211|Alphaproteobacteria,4BD01@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8584117_0	555779.Dthio_PD2719	5.076e-46	171.0	COG5017@1|root,COG5017@2|Bacteria,1MZGV@1224|Proteobacteria,432TQ@68525|delta/epsilon subdivisions,2WXT6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
WH3_k127_8584117_2	195253.Syn6312_0467	2.466e-05	51.0	COG0726@1|root,COG2367@1|root,COG0726@2|Bacteria,COG2367@2|Bacteria,1G02J@1117|Cyanobacteria,1H1V4@1129|Synechococcus	1117|Cyanobacteria	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
WH3_k127_8593445_0	1122180.Lokhon_02513	1.33e-23	102.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,2TVY5@28211|Alphaproteobacteria,2PA28@245186|Loktanella	28211|Alphaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH3_k127_862415_0	1499967.BAYZ01000102_gene3556	3.109e-201	643.0	COG0826@1|root,COG0826@2|Bacteria,2NPQH@2323|unclassified Bacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	ydcP	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
WH3_k127_862415_1	1047013.AQSP01000139_gene2368	1.924e-45	170.0	COG0730@1|root,COG0730@2|Bacteria,2NRZN@2323|unclassified Bacteria	2|Bacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WH3_k127_8658568_0	1292034.OR37_00011	9.593e-142	461.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,2TS6P@28211|Alphaproteobacteria,2KHQ3@204458|Caulobacterales	204458|Caulobacterales	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WH3_k127_868923_2	756499.Desde_2209	2.937e-18	87.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia,26343@186807|Peptococcaceae	186801|Clostridia	S	PFAM thioesterase superfamily	FcbC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
WH3_k127_868923_1	877455.Metbo_2450	1.537e-123	401.0	COG1013@1|root,arCOG01599@2157|Archaea,2XTW2@28890|Euryarchaeota,23PWY@183925|Methanobacteria	183925|Methanobacteria	C	TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
WH3_k127_868923_0	309803.CTN_1411	2.446e-166	537.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GC9M@200918|Thermotogae	200918|Thermotogae	C	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1164	POR,POR_N
WH3_k127_8695392_0	192952.MM_1936	9.161e-33	142.0	arCOG02527@1|root,arCOG02527@2157|Archaea,2XZJV@28890|Euryarchaeota,2NA0Y@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8695392_1	96561.Dole_2003	2.747e-08	58.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,42MVD@68525|delta/epsilon subdivisions,2WIY3@28221|Deltaproteobacteria,2MIPS@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
WH3_k127_8700634_4	1123070.KB899255_gene1376	8.774e-06	49.0	COG0629@1|root,COG0629@2|Bacteria,46VGA@74201|Verrucomicrobia,2IUK4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WH3_k127_8700634_3	575540.Isop_1027	3.988e-16	81.0	COG0238@1|root,COG0238@2|Bacteria,2J0IC@203682|Planctomycetes	203682|Planctomycetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
WH3_k127_8700634_2	530564.Psta_2667	4.153e-25	111.0	COG0359@1|root,COG0359@2|Bacteria,2IZCC@203682|Planctomycetes	203682|Planctomycetes	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
WH3_k127_8700634_0	1142394.PSMK_13120	5.509e-134	443.0	COG0305@1|root,COG0305@2|Bacteria,2IXJT@203682|Planctomycetes	203682|Planctomycetes	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
WH3_k127_8700634_1	247490.KSU1_B0552	9.988e-68	249.0	COG4775@1|root,COG4775@2|Bacteria,2IWWA@203682|Planctomycetes	203682|Planctomycetes	M	Outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
WH3_k127_8735530_1	575540.Isop_1265	4.046e-14	79.0	COG1466@1|root,COG1466@2|Bacteria,2IZVJ@203682|Planctomycetes	203682|Planctomycetes	L	DNA polymerase III, delta' subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
WH3_k127_8735530_0	247490.KSU1_B0370	3.322e-52	189.0	COG0188@1|root,COG0188@2|Bacteria,2IY0U@203682|Planctomycetes	203682|Planctomycetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WH3_k127_8756004_1	1262915.BN574_00035	3.181e-12	67.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H314@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
WH3_k127_8756004_2	643648.Slip_1894	3.708e-12	74.0	28JE3@1|root,2Z98B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
WH3_k127_8756004_0	28042.GU90_01465	1.894e-76	265.0	COG0388@1|root,COG0388@2|Bacteria,2I9ZC@201174|Actinobacteria,4E6QQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
WH3_k127_8783549_1	1046625.AFQY01000003_gene2378	0.0002518	51.0	COG0640@1|root,COG0640@2|Bacteria,1N0B6@1224|Proteobacteria,1S9GJ@1236|Gammaproteobacteria,3NINY@468|Moraxellaceae	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_36
WH3_k127_8783549_0	1173020.Cha6605_4559	2.58e-11	72.0	COG5545@1|root,COG5545@2|Bacteria,1G1ZC@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Virulence-associated E	-	-	-	-	-	-	-	-	-	-	-	-	PriCT_2,Prim-Pol,VirE
WH3_k127_8786079_1	1499967.BAYZ01000115_gene2932	1.906e-118	392.0	COG0112@1|root,COG0404@1|root,COG0112@2|Bacteria,COG0404@2|Bacteria,2NP28@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	gcvT	GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204	2.1.2.1,2.1.2.10,2.2.1.8	ko:K00600,ko:K00605,ko:K18847	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R01221,R02300,R04125,R09099	RC00022,RC00069,RC00112,RC00183,RC01583,RC02834,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C,SHMT
WH3_k127_8786079_2	290397.Adeh_1244	3.683e-34	135.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,42RS9@68525|delta/epsilon subdivisions,2WP93@28221|Deltaproteobacteria,2Z1I1@29|Myxococcales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
WH3_k127_8786079_0	1379281.AVAG01000071_gene734	6.525e-159	512.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,42MQ1@68525|delta/epsilon subdivisions,2WJII@28221|Deltaproteobacteria,2M9HZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
WH3_k127_8786079_3	1122605.KB893626_gene2833	1.374e-16	82.0	COG1943@1|root,COG1943@2|Bacteria,4NQTF@976|Bacteroidetes,1ISSF@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WH3_k127_8821211_1	909663.KI867151_gene3160	4.072e-58	209.0	COG2197@1|root,COG2197@2|Bacteria,1RARA@1224|Proteobacteria,43B1G@68525|delta/epsilon subdivisions,2X5U5@28221|Deltaproteobacteria,2MRK4@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH3_k127_8821211_0	237368.SCABRO_03963	8.797e-271	847.0	COG0443@1|root,COG0443@2|Bacteria,2IWWS@203682|Planctomycetes	203682|Planctomycetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WH3_k127_8821211_2	243164.DET0109	8.753e-31	126.0	COG0680@1|root,COG0680@2|Bacteria,2G7BV@200795|Chloroflexi,34D7G@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
WH3_k127_8821351_1	742727.HMPREF9447_01923	2.055e-07	54.0	COG3507@1|root,COG3507@2|Bacteria,4NHJX@976|Bacteroidetes,2FPY3@200643|Bacteroidia,4AP6Y@815|Bacteroidaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8821351_0	1242864.D187_007843	1.243e-69	258.0	COG2503@1|root,COG2503@2|Bacteria,1QY3J@1224|Proteobacteria	1224|Proteobacteria	G	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_883461_0	314278.NB231_09418	3.575e-139	448.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1WWU6@135613|Chromatiales	135613|Chromatiales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
WH3_k127_883461_1	247490.KSU1_B0639	2.165e-59	218.0	COG1774@1|root,COG1774@2|Bacteria,2IWZD@203682|Planctomycetes	203682|Planctomycetes	S	signal peptidase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
WH3_k127_8836146_0	1142394.PSMK_30050	4.363e-155	500.0	COG1217@1|root,COG1217@2|Bacteria,2IY3Q@203682|Planctomycetes	203682|Planctomycetes	T	membrane GTPase involved in stress response	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
WH3_k127_8846804_2	1396418.BATQ01000146_gene3493	1.773e-06	51.0	COG1520@1|root,COG1520@2|Bacteria,46TV4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
WH3_k127_8846804_0	1168034.FH5T_01535	1.366e-128	428.0	COG0493@1|root,COG0493@2|Bacteria,4P2CU@976|Bacteroidetes,2FXPN@200643|Bacteroidia	976|Bacteroidetes	E	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_20
WH3_k127_8875932_0	314230.DSM3645_22561	5.602e-20	94.0	COG1198@1|root,COG1198@2|Bacteria,2IY1F@203682|Planctomycetes	203682|Planctomycetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
WH3_k127_8882863_0	1125863.JAFN01000001_gene2969	1.016e-90	311.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
WH3_k127_8905306_0	443144.GM21_2706	5.057e-33	139.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,43SF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
WH3_k127_8905306_1	1408321.JNJD01000006_gene797	7.311e-07	57.0	2DNZJ@1|root,32ZX7@2|Bacteria,1VHMI@1239|Firmicutes,24SBG@186801|Clostridia,27PZQ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
WH3_k127_8924828_0	867903.ThesuDRAFT_00439	2.391e-114	388.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3WCIN@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WH3_k127_8924828_1	264462.Bd0734	9.467e-67	234.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2MTU1@213481|Bdellovibrionales,2WJWD@28221|Deltaproteobacteria	213481|Bdellovibrionales	G	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
WH3_k127_8926571_0	29730.Gorai.013G116200.1	3.974e-14	73.0	COG0169@1|root,KOG0692@2759|Eukaryota,37SRE@33090|Viridiplantae,3GG8V@35493|Streptophyta	35493|Streptophyta	E	dehydratase shikimate dehydrogenase	-	-	1.1.1.25,4.2.1.10	ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_dh_N
WH3_k127_8926571_1	1303518.CCALI_02244	1.537e-09	63.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
WH3_k127_8966615_2	926562.Oweho_0880	8.026e-33	136.0	COG1361@1|root,COG3291@1|root,COG4935@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NGW4@976|Bacteroidetes,1IK8B@117743|Flavobacteriia	976|Bacteroidetes	O	Peptide-N-glycosidase F, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,N-glycanase_C
WH3_k127_8966615_1	530564.Psta_0111	6.238e-60	237.0	COG1452@1|root,COG1452@2|Bacteria,2IXFV@203682|Planctomycetes	203682|Planctomycetes	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	OstA_C
WH3_k127_8966615_0	416591.Tlet_1891	7.245e-128	415.0	COG0191@1|root,COG0191@2|Bacteria,2GC6U@200918|Thermotogae	200918|Thermotogae	G	Fructose-1,6-bisphosphate aldolase, class II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
WH3_k127_8966615_3	1408424.JHYI01000012_gene2248	1.332e-17	97.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S41A family	ctpB	GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009653,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030154,GO:0030288,GO:0030313,GO:0030435,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043603,GO:0043900,GO:0043902,GO:0043934,GO:0044237,GO:0044238,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1900190,GO:1900192,GO:1901564	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
WH3_k127_89865_2	402777.KB235904_gene4203	5.347e-32	135.0	COG4872@1|root,COG4872@2|Bacteria,1G2MS@1117|Cyanobacteria,1H75N@1150|Oscillatoriales	1117|Cyanobacteria	S	membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
WH3_k127_89865_1	247490.KSU1_C0166	7.224e-67	244.0	COG0772@1|root,COG0772@2|Bacteria,2IZRI@203682|Planctomycetes	203682|Planctomycetes	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
WH3_k127_89865_0	1192034.CAP_0825	1.222e-77	268.0	COG2133@1|root,COG3055@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8986572_1	877415.JNJQ01000004_gene1540	1.341e-13	76.0	COG0778@1|root,COG0778@2|Bacteria,1V7RH@1239|Firmicutes	1239|Firmicutes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WH3_k127_8986572_0	1156937.MFUM_810019	1.668e-122	402.0	COG0766@1|root,COG0766@2|Bacteria,46S6Q@74201|Verrucomicrobia,37G73@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
WH3_k127_9000126_1	1029718.SFBM_0572	3.246e-07	61.0	COG1868@1|root,COG1868@2|Bacteria,1TPTM@1239|Firmicutes,24AGV@186801|Clostridia,36EHT@31979|Clostridiaceae	186801|Clostridia	N	flagellar motor switch protein FliM	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
WH3_k127_9000126_0	1115512.EH105704_01_06770	3.911e-92	321.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,3XP3S@561|Escherichia	1236|Gammaproteobacteria	T	Member of the two-component regulatory system AtoS AtoC. In the presence of acetoacetate, AtoS AtoC stimulates the expression of the atoDAEB operon, leading to short chain fatty acid catabolism and activation of the poly-(R)-3-hydroxybutyrate (cPHB) biosynthetic pathway. Also induces the operon in response to spermidine. Involved in the regulation of motility and chemotaxis, via transcriptional induction of the flagellar regulon. AtoC acts by binding directly to the promoter region of the target genes. In addition to its role as a transcriptional regulator, functions as a post- translational regulator that inhibits polyamine biosynthesis via regulation of ornithine decarboxylase (ODC)	atoC	GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K02481,ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WH3_k127_9000251_1	640081.Dsui_0198	2.422e-10	68.0	2CWET@1|root,32SZJ@2|Bacteria,1N1XQ@1224|Proteobacteria,2W4KN@28216|Betaproteobacteria,2KZ9D@206389|Rhodocyclales	206389|Rhodocyclales	S	Phage gp6-like head-tail connector protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_connect_1
WH3_k127_9017878_0	1142394.PSMK_11160	3.998e-171	558.0	COG2217@1|root,COG2217@2|Bacteria,2IWRY@203682|Planctomycetes	203682|Planctomycetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5,3.6.3.54	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5,3.A.3.6	-	-	Band_7,E1-E2_ATPase,Hydrolase
WH3_k127_9017878_1	1142394.PSMK_15640	2.85e-95	326.0	COG1131@1|root,COG1131@2|Bacteria,2IY18@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH3_k127_9017878_2	1265505.ATUG01000003_gene184	6.544e-07	61.0	COG1277@1|root,COG1277@2|Bacteria,1NCXV@1224|Proteobacteria,42VK2@68525|delta/epsilon subdivisions,2WRNT@28221|Deltaproteobacteria,2MPXF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
WH3_k127_9030683_0	886293.Sinac_4399	5.03e-57	210.0	COG0577@1|root,COG0577@2|Bacteria,2IY2P@203682|Planctomycetes	203682|Planctomycetes	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02004,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
WH3_k127_9030683_1	1236959.BAMT01000001_gene1729	1.503e-27	123.0	COG1538@1|root,COG1538@2|Bacteria,1NEHN@1224|Proteobacteria,2VYWE@28216|Betaproteobacteria,2KKVJ@206350|Nitrosomonadales	206350|Nitrosomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WH3_k127_9035342_1	515622.bpr_I2038	4.499e-24	104.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,4BWRY@830|Butyrivibrio	186801|Clostridia	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
WH3_k127_9035342_0	313612.L8106_12095	8.055e-71	245.0	COG1051@1|root,COG1051@2|Bacteria,1G4H7@1117|Cyanobacteria,1HEY6@1150|Oscillatoriales	1117|Cyanobacteria	F	Hydrolase of X-linked nucleoside diphosphate N terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N
WH3_k127_9035342_2	1379698.RBG1_1C00001G0415	3.233e-18	89.0	COG5316@1|root,COG5316@2|Bacteria,2NPBR@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
WH3_k127_903554_0	278957.ABEA03000174_gene3362	1.728e-06	59.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
WH3_k127_9046950_1	937777.Deipe_2193	7.02e-26	109.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	aadD	-	-	ko:K17882	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	KNTase_C,NTP_transf_2
WH3_k127_9046950_0	1123242.JH636436_gene228	8.197e-41	155.0	COG0764@1|root,COG0764@2|Bacteria,2J09I@203682|Planctomycetes	203682|Planctomycetes	I	3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein)	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
WH3_k127_9046950_2	243090.RB7168	4.931e-12	67.0	COG0236@1|root,COG0236@2|Bacteria,2J04I@203682|Planctomycetes	203682|Planctomycetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
WH3_k127_9064003_0	1123008.KB905692_gene286	2.293e-162	523.0	COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,2FRW6@200643|Bacteroidia	976|Bacteroidetes	U	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	xylE	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
WH3_k127_9064003_1	1286632.P278_20620	6.959e-154	494.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,1HXW7@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl hydrolase family 109	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WH3_k127_9074505_4	1142394.PSMK_01960	1.005e-16	82.0	COG0636@1|root,COG0636@2|Bacteria,2J0QD@203682|Planctomycetes	203682|Planctomycetes	P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
WH3_k127_9074505_1	1191523.MROS_0276	1.382e-37	152.0	COG0356@1|root,COG0356@2|Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
WH3_k127_9074505_0	886293.Sinac_0178	3.419e-77	272.0	COG2189@1|root,COG2189@2|Bacteria,2IWRP@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
WH3_k127_9074505_2	237368.SCABRO_03694	4.037e-32	138.0	COG0815@1|root,COG0815@2|Bacteria,2IWUW@203682|Planctomycetes	203682|Planctomycetes	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
WH3_k127_9101928_0	1408473.JHXO01000010_gene3743	0.0	1013.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,2FMXD@200643|Bacteroidia	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
WH3_k127_9101928_1	401053.AciPR4_1244	3.29e-135	446.0	COG3119@1|root,COG3119@2|Bacteria,3Y6D1@57723|Acidobacteria,2JK8D@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
WH3_k127_9101928_2	338963.Pcar_1381	1.155e-47	173.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,42MM6@68525|delta/epsilon subdivisions,2WJ53@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
WH3_k127_9145286_0	759914.BP951000_0513	1.217e-188	599.0	COG0441@1|root,COG0441@2|Bacteria,2J5ID@203691|Spirochaetes	203691|Spirochaetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
WH3_k127_9177038_1	439235.Dalk_5076	1.57e-77	265.0	COG2268@1|root,COG2268@2|Bacteria,1P50K@1224|Proteobacteria,42PJG@68525|delta/epsilon subdivisions,2WQ9J@28221|Deltaproteobacteria,2MMDR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Flotillin	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
WH3_k127_9177038_3	877418.ATWV01000001_gene1455	1.255e-26	110.0	COG0254@1|root,COG0254@2|Bacteria,2J93Z@203691|Spirochaetes	203691|Spirochaetes	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
WH3_k127_9177038_0	521674.Plim_0922	7.125e-106	355.0	COG0216@1|root,COG0216@2|Bacteria,2IY77@203682|Planctomycetes	203682|Planctomycetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WH3_k127_9177038_2	1142394.PSMK_11820	6.524e-50	182.0	COG2019@1|root,COG2019@2|Bacteria	2|Bacteria	F	adenylate kinase activity	-	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AAA_17
WH3_k127_9191688_4	203275.BFO_1397	1.888e-05	50.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874,Glyco_hydro_42
WH3_k127_9191688_3	1142394.PSMK_02400	6.383e-15	79.0	COG0727@1|root,COG0727@2|Bacteria,2J0KU@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9191688_0	335543.Sfum_1657	3.842e-77	269.0	COG0598@1|root,COG0598@2|Bacteria,1RGGI@1224|Proteobacteria,42UX4@68525|delta/epsilon subdivisions,2WQYH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Mg2 transporter protein CorA family protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
WH3_k127_9191688_1	314230.DSM3645_01741	2.696e-36	142.0	COG0727@1|root,COG0727@2|Bacteria,2IZM1@203682|Planctomycetes	203682|Planctomycetes	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
WH3_k127_9191688_2	1121423.JONT01000001_gene2135	1.23e-20	94.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,24R29@186801|Clostridia,26375@186807|Peptococcaceae	186801|Clostridia	O	PFAM nitrogen-fixing NifU domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NifU
WH3_k127_9194173_4	203119.Cthe_2537	1.207e-17	86.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1TQXK@1239|Firmicutes,25EK3@186801|Clostridia,3WISI@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D3
WH3_k127_9194173_2	1121324.CLIT_11c02540	2.653e-45	181.0	COG0155@1|root,COG0155@2|Bacteria,1TS58@1239|Firmicutes,248DQ@186801|Clostridia	186801|Clostridia	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	nirA	-	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr,TusA
WH3_k127_9194173_0	1499967.BAYZ01000079_gene883	5.756e-228	711.0	COG2873@1|root,COG2873@2|Bacteria,2NQN4@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
WH3_k127_9194173_1	292459.STH1137	1.809e-124	406.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WH3_k127_9194173_5	272942.RCAP_rcc01778	4.183e-12	77.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2TRYX@28211|Alphaproteobacteria,1FBHP@1060|Rhodobacter	28211|Alphaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WH3_k127_9194173_3	1142394.PSMK_15840	1.404e-33	134.0	COG0134@1|root,COG0134@2|Bacteria,2IX3M@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
WH3_k127_9245045_2	29581.BW37_00341	0.000285	48.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WGK9@28216|Betaproteobacteria,47913@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg,dCache_1
WH3_k127_9245045_0	243231.GSU1928	1.048e-101	356.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,43TPU@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HAMP,HATPase_c,HisKA,Hpt,Response_reg
WH3_k127_9245045_1	1454004.AW11_01746	1.466e-23	109.0	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,2VUUB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
WH3_k127_9265076_0	1122915.AUGY01000019_gene6392	1.488e-117	387.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,26RSM@186822|Paenibacillaceae	91061|Bacilli	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
WH3_k127_9265076_1	1123508.JH636445_gene6737	1.726e-05	51.0	COG1381@1|root,COG1381@2|Bacteria,2IZU9@203682|Planctomycetes	203682|Planctomycetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
WH3_k127_9271156_0	1304874.JAFY01000005_gene1289	7.519e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,3TBS0@508458|Synergistetes	508458|Synergistetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
WH3_k127_9289422_0	1142394.PSMK_22330	5.004e-42	171.0	COG1596@1|root,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
WH3_k127_9324061_1	189426.PODO_15795	1.856e-14	84.0	COG3250@1|root,COG3405@1|root,COG3250@2|Bacteria,COG3405@2|Bacteria,1VT7I@1239|Firmicutes,4HV43@91061|Bacilli,27744@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_8,fn3
WH3_k127_9324061_0	867845.KI911784_gene771	8.394e-77	268.0	COG2273@1|root,COG2273@2|Bacteria,2G7RY@200795|Chloroflexi,377GW@32061|Chloroflexia	32061|Chloroflexia	G	Glycoside hydrolase family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
WH3_k127_9325015_0	314230.DSM3645_19987	5.563e-118	399.0	COG0323@1|root,COG0323@2|Bacteria,2IXI2@203682|Planctomycetes	203682|Planctomycetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
WH3_k127_9325015_1	373903.Hore_18990	6.331e-42	166.0	COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,24AKE@186801|Clostridia,3WAIV@53433|Halanaerobiales	186801|Clostridia	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
WH3_k127_9325108_1	338966.Ppro_3420	5.775e-10	67.0	COG1406@1|root,COG1406@2|Bacteria,1N38Q@1224|Proteobacteria,42UIA@68525|delta/epsilon subdivisions,2WQV5@28221|Deltaproteobacteria,43UR5@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	Chemotaxis phosphatase CheX	cheX64H	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
WH3_k127_9325108_0	1382359.JIAL01000001_gene2158	3.399e-31	127.0	COG0745@1|root,COG0745@2|Bacteria,3Y55U@57723|Acidobacteria,2JJQC@204432|Acidobacteriia	204432|Acidobacteriia	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
WH3_k127_9332170_1	861299.J421_0144	2.415e-138	451.0	COG1004@1|root,COG1004@2|Bacteria,1ZTH3@142182|Gemmatimonadetes	2|Bacteria	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WH3_k127_9332170_4	1519464.HY22_02245	1.031e-49	181.0	COG4914@1|root,COG4914@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
WH3_k127_9332170_2	316067.Geob_2923	4.137e-105	350.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2WJMZ@28221|Deltaproteobacteria,43U74@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	uge	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
WH3_k127_9332170_0	1045858.Bint_1756	3.884e-159	507.0	COG1089@1|root,COG1089@2|Bacteria,2J78G@203691|Spirochaetes	203691|Spirochaetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
WH3_k127_9332170_3	1047013.AQSP01000133_gene2141	6.193e-82	285.0	COG2605@1|root,COG2605@2|Bacteria	2|Bacteria	G	GHMP kinase	fkp	-	2.7.1.52	ko:K05305	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R03161	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Fucokinase,GHMP_kinases_C,GHMP_kinases_N
WH3_k127_9339633_3	195250.CM001776_gene3792	1.048e-10	70.0	COG0524@1|root,COG0524@2|Bacteria,1G2YU@1117|Cyanobacteria,1H46E@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
WH3_k127_9339633_1	1142394.PSMK_27400	1.158e-41	160.0	COG0745@1|root,COG0745@2|Bacteria,2IY82@203682|Planctomycetes	203682|Planctomycetes	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Response_reg
WH3_k127_9339633_0	756272.Plabr_1963	2.364e-112	378.0	COG0612@1|root,COG0612@2|Bacteria,2IWSI@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WH3_k127_9339633_2	344747.PM8797T_30586	1.182e-25	110.0	COG0612@1|root,COG0612@2|Bacteria,2IY7Q@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WH3_k127_9342526_1	420246.GTNG_0212	7.285e-24	111.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,1WF2Y@129337|Geobacillus	91061|Bacilli	O	Glycoprotease family	yeaZ	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WH3_k127_9342526_0	1499967.BAYZ01000057_gene4710	3.059e-31	127.0	COG0501@1|root,COG0501@2|Bacteria,2NS4G@2323|unclassified Bacteria	2|Bacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
WH3_k127_9350078_0	639282.DEFDS_2173	1.17e-135	444.0	COG0249@1|root,COG0249@2|Bacteria,2GEK4@200930|Deferribacteres	200930|Deferribacteres	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WH3_k127_935285_0	1123508.JH636449_gene7292	3.191e-87	297.0	COG0414@1|root,COG0414@2|Bacteria,2IYUG@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
WH3_k127_9362914_1	42256.RradSPS_1227	3.23e-20	105.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
WH3_k127_9362914_0	1128427.KB904821_gene2717	1.936e-114	375.0	28KU8@1|root,2ZCM9@2|Bacteria,1G5AX@1117|Cyanobacteria,1HAQ7@1150|Oscillatoriales	1117|Cyanobacteria	S	STELLO glycosyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	STELLO
WH3_k127_9374884_1	536233.CLO_0167	5.432e-11	64.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,36ETK@31979|Clostridiaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
WH3_k127_9374884_0	1046627.BZARG_2253	3.961e-24	107.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,1HY0Y@117743|Flavobacteriia	976|Bacteroidetes	T	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
WH3_k127_9390463_2	1166018.FAES_0769	9.576e-17	83.0	28KU8@1|root,2ZCM9@2|Bacteria,4NP3P@976|Bacteroidetes,47US8@768503|Cytophagia	976|Bacteroidetes	S	STELLO glycosyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	STELLO
WH3_k127_9390463_1	1128427.KB904821_gene2716	1.587e-82	282.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WH3_k127_9390463_0	697282.Mettu_4058	4.642e-92	314.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1XDPK@135618|Methylococcales	135618|Methylococcales	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
WH3_k127_9391483_0	1142394.PSMK_15730	7.774e-45	177.0	COG0653@1|root,COG0653@2|Bacteria,2IXIT@203682|Planctomycetes	203682|Planctomycetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WH3_k127_9422758_1	338966.Ppro_2950	1.022e-46	171.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,43B0E@68525|delta/epsilon subdivisions,2X6EG@28221|Deltaproteobacteria,43U7H@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
WH3_k127_9422758_0	338966.Ppro_2952	4.374e-131	421.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,42KZX@68525|delta/epsilon subdivisions,2WM2N@28221|Deltaproteobacteria,43SZW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	KR domain	-	-	1.1.1.381	ko:K16066	ko00240,ko00260,ko01100,map00240,map00260,map01100	-	R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000	-	-	-	adh_short
WH3_k127_9422758_2	316067.Geob_1934	2.693e-29	125.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
WH3_k127_9424340_0	1047013.AQSP01000144_gene920	1.151e-129	421.0	COG0426@1|root,COG0426@2|Bacteria,2NPHV@2323|unclassified Bacteria	2|Bacteria	C	Metallo-beta-lactamase superfamily	dfa1	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Flavodoxin_1,Lactamase_B
WH3_k127_9424340_1	555779.Dthio_PD3435	1.252e-21	95.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2WNA5@28221|Deltaproteobacteria,2MBFX@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
WH3_k127_9425339_0	530564.Psta_3630	1.088e-35	146.0	COG4972@1|root,COG4972@2|Bacteria,2IZC6@203682|Planctomycetes	203682|Planctomycetes	NU	pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
WH3_k127_9426629_1	1123242.JH636436_gene709	3.712e-07	59.0	2DS9W@1|root,33F72@2|Bacteria,2J184@203682|Planctomycetes	203682|Planctomycetes	S	Flagellar assembly protein FliH	-	-	-	-	-	-	-	-	-	-	-	-	FliH
WH3_k127_9426629_0	1408422.JHYF01000001_gene2978	6.572e-147	479.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,25E6B@186801|Clostridia,36FF4@31979|Clostridiaceae	186801|Clostridia	NU	Flagellar protein export ATPase FliI	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
WH3_k127_9429382_0	391625.PPSIR1_02913	3.193e-100	339.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2YU14@29|Myxococcales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
WH3_k127_9429382_1	1142394.PSMK_16420	9.058e-38	143.0	COG0234@1|root,COG0234@2|Bacteria,2IZTF@203682|Planctomycetes	203682|Planctomycetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
WH3_k127_9435935_1	667014.Thein_0462	8.655e-29	119.0	COG1706@1|root,COG1706@2|Bacteria,2GGRG@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
WH3_k127_9435935_3	83219.PM02_15825	6.766e-05	51.0	2EIU1@1|root,33CJD@2|Bacteria,1PE2Q@1224|Proteobacteria,2V5W1@28211|Alphaproteobacteria,3ZZ72@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Rod binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Rod-binding
WH3_k127_9435935_0	1123508.JH636444_gene5169	5.761e-100	350.0	COG1256@1|root,COG1256@2|Bacteria,2IXRV@203682|Planctomycetes	203682|Planctomycetes	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WH3_k127_9435935_2	237368.SCABRO_02727	4.751e-25	115.0	COG1344@1|root,COG1344@2|Bacteria,2J11W@203682|Planctomycetes	203682|Planctomycetes	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	-	-	-	-	-	-	-	-	-	Flagellin_N
WH3_k127_945332_0	1195236.CTER_2213	1.403e-170	545.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,248G9@186801|Clostridia,3WHHZ@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
WH3_k127_945332_1	639282.DEFDS_0963	5.076e-42	156.0	COG4747@1|root,COG4747@2|Bacteria,2GFKS@200930|Deferribacteres	200930|Deferribacteres	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT
WH3_k127_9455055_1	1191523.MROS_1984	5.912e-26	117.0	COG0720@1|root,COG0720@2|Bacteria	2|Bacteria	H	synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
WH3_k127_9455055_0	530564.Psta_2339	2.713e-74	254.0	COG0302@1|root,COG0302@2|Bacteria,2IYUA@203682|Planctomycetes	203682|Planctomycetes	H	PFAM GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
WH3_k127_9462222_0	335541.Swol_1078	5.086e-44	173.0	COG5492@1|root,COG5492@2|Bacteria,1V7TS@1239|Firmicutes,25F4B@186801|Clostridia,42KX4@68298|Syntrophomonadaceae	1239|Firmicutes	N	Surface proteins containing Ig-like domains-like	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9465411_1	1121346.KB899814_gene1751	9.167e-29	118.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,4HACP@91061|Bacilli,26SVR@186822|Paenibacillaceae	91061|Bacilli	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
WH3_k127_9465411_0	396588.Tgr7_0623	1.669e-146	473.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,1RRCR@1236|Gammaproteobacteria,1WYMQ@135613|Chromatiales	135613|Chromatiales	K	Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
WH3_k127_9465411_2	351627.Csac_2050	2.394e-23	105.0	COG4747@1|root,COG4747@2|Bacteria,1V7U2@1239|Firmicutes,24JE5@186801|Clostridia,42GI5@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
WH3_k127_9469205_0	247490.KSU1_C0061	1.468e-93	314.0	COG0182@1|root,COG0182@2|Bacteria,2IWRJ@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
WH3_k127_9469205_1	497964.CfE428DRAFT_4451	3.259e-15	85.0	2C16S@1|root,2ZHJB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9469620_0	573413.Spirs_0598	7.931e-119	391.0	COG2871@1|root,COG2871@2|Bacteria,2JBKD@203691|Spirochaetes	203691|Spirochaetes	C	Oxidoreductase FAD-binding domain	-	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
WH3_k127_9469620_1	459349.CLOAM0926	2.453e-11	68.0	2B4IF@1|root,31XAC@2|Bacteria,2NRBG@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9523689_0	247490.KSU1_D0944	4.572e-129	420.0	COG4992@1|root,COG4992@2|Bacteria,2IWTF@203682|Planctomycetes	203682|Planctomycetes	E	COG4992 Ornithine acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WH3_k127_9523689_1	926569.ANT_18090	1.805e-24	106.0	COG0078@1|root,COG0078@2|Bacteria,2G5Z9@200795|Chloroflexi	200795|Chloroflexi	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WH3_k127_9525834_0	589865.DaAHT2_1400	1.657e-115	390.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MI79@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WH3_k127_9539545_1	1289135.A966_01140	1.691e-62	221.0	COG2344@1|root,COG2344@2|Bacteria,2J89C@203691|Spirochaetes	203691|Spirochaetes	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
WH3_k127_9539545_0	1125863.JAFN01000001_gene2622	8.987e-124	408.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2WJCQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
WH3_k127_9588383_1	1210884.HG799465_gene12149	3.002e-19	98.0	2EPQ7@1|root,33HAS@2|Bacteria,2J1P9@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9588383_0	1298920.KI911353_gene4695	5.091e-53	201.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,21XEA@1506553|Lachnoclostridium	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
WH3_k127_95903_1	1128421.JAGA01000003_gene2785	1.486e-24	111.0	COG0472@1|root,COG0472@2|Bacteria,2NR03@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
WH3_k127_95903_0	1499680.CCFE01000011_gene321	8.198e-66	236.0	COG0189@1|root,COG0189@2|Bacteria,1UIBP@1239|Firmicutes,4HDB7@91061|Bacilli,1ZDUR@1386|Bacillus	91061|Bacilli	HJ	ATP-grasp domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3
WH3_k127_95903_2	1396141.BATP01000057_gene3046	6.716e-07	54.0	2AVZM@1|root,31MU0@2|Bacteria,46X67@74201|Verrucomicrobia,2IUMV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9595441_0	573413.Spirs_1641	3.135e-145	466.0	COG0493@1|root,COG0493@2|Bacteria,2J5FP@203691|Spirochaetes	203691|Spirochaetes	C	glutamate synthase (NADPH), homotetrameric	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
WH3_k127_9603917_0	926556.Echvi_1680	1.412e-122	404.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,47KNU@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
WH3_k127_9603917_1	314230.DSM3645_10617	8.802e-36	143.0	COG3420@1|root,COG3420@2|Bacteria,2J2DV@203682|Planctomycetes	203682|Planctomycetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
WH3_k127_9624299_1	316067.Geob_0070	3.093e-13	83.0	COG5373@1|root,COG5373@2|Bacteria,1QFJD@1224|Proteobacteria,43499@68525|delta/epsilon subdivisions,2X2KI@28221|Deltaproteobacteria,43VWU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
WH3_k127_9624299_2	1329516.JPST01000019_gene2722	1.906e-10	74.0	COG5373@1|root,COG5373@2|Bacteria,1V0DE@1239|Firmicutes,4HER0@91061|Bacilli	91061|Bacilli	S	membrane	Otg1	-	-	-	-	-	-	-	-	-	-	-	DUF2339
WH3_k127_9624299_0	886293.Sinac_1305	1.233e-61	226.0	COG0472@1|root,COG0472@2|Bacteria,2IXB8@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
WH3_k127_9624299_3	765420.OSCT_0486	1.4e-07	65.0	COG3307@1|root,COG3307@2|Bacteria,2G9UT@200795|Chloroflexi,3777N@32061|Chloroflexia	32061|Chloroflexia	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WH3_k127_9624811_0	880072.Desac_0771	7.657e-57	209.0	2DV5M@1|root,33U68@2|Bacteria,1NUIA@1224|Proteobacteria,42ZFX@68525|delta/epsilon subdivisions,2WV1Z@28221|Deltaproteobacteria	880072.Desac_0771|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9624811_2	243090.RB5399	1.762e-05	55.0	COG2165@1|root,COG2165@2|Bacteria,2IYZV@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
WH3_k127_9624811_3	118163.Ple7327_3808	0.0001477	46.0	COG3385@1|root,COG3385@2|Bacteria,1G3T3@1117|Cyanobacteria,3VMB3@52604|Pleurocapsales	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Nterm_IS4
WH3_k127_9624811_4	1142394.PSMK_03080	0.0005631	49.0	COG4967@1|root,COG4967@2|Bacteria	2|Bacteria	NU	type IV pilus modification protein PilV	ppdC	-	-	ko:K02458,ko:K02671,ko:K02681	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15	-	-	N_methyl,T2SSppdC
WH3_k127_9624811_1	1142394.PSMK_25970	1.502e-33	132.0	COG1459@1|root,COG1459@2|Bacteria,2IYHA@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
WH3_k127_9643286_0	485917.Phep_1459	1.657e-157	515.0	COG4225@1|root,COG4225@2|Bacteria,4NF1N@976|Bacteroidetes,1IP96@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Heparinase II III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
WH3_k127_9648428_1	234267.Acid_2265	2.671e-24	104.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
WH3_k127_9648428_0	234267.Acid_2266	1.036e-144	488.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
WH3_k127_9719157_0	661478.OP10G_2391	1.123e-121	402.0	COG1409@1|root,COG3669@1|root,COG1409@2|Bacteria,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C,PA14
WH3_k127_9735117_1	268407.PWYN_18665	3.743e-25	107.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,26Q92@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WH3_k127_9735117_0	530564.Psta_1417	1.043e-96	323.0	COG0777@1|root,COG0777@2|Bacteria,2IXWA@203682|Planctomycetes	203682|Planctomycetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WH3_k127_9735117_2	1121468.AUBR01000041_gene1696	0.0009153	44.0	COG3428@1|root,COG3428@2|Bacteria,1V9YB@1239|Firmicutes,24MQT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
WH3_k127_9755783_0	443143.GM18_1847	4.32e-132	428.0	COG0502@1|root,COG0502@2|Bacteria,1R8GT@1224|Proteobacteria,42QNT@68525|delta/epsilon subdivisions,2WN06@28221|Deltaproteobacteria,43T1U@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
WH3_k127_9755783_2	267377.MMP0019	1.358e-06	56.0	arCOG06587@1|root,arCOG06587@2157|Archaea,2Y1TF@28890|Euryarchaeota,23RC6@183939|Methanococci	183939|Methanococci	S	Protein of unknown function (DUF2798)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
WH3_k127_9755783_1	338966.Ppro_1494	1.36e-67	232.0	COG0486@1|root,COG0486@2|Bacteria,1PM94@1224|Proteobacteria,42MYX@68525|delta/epsilon subdivisions,2WJE4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM Small GTP-binding protein	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
WH3_k127_9759287_0	543734.LCABL_17760	3.219e-104	345.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,3F3Z1@33958|Lactobacillaceae	91061|Bacilli	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
WH3_k127_9759287_1	1195236.CTER_0563	5.776e-61	218.0	COG0145@1|root,COG0145@2|Bacteria,1V3GN@1239|Firmicutes,25DNJ@186801|Clostridia,3WPEF@541000|Ruminococcaceae	186801|Clostridia	EQ	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
WH3_k127_9759287_2	1122927.KB895422_gene3821	1.802e-12	76.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,4HC8Q@91061|Bacilli,26UNW@186822|Paenibacillaceae	91061|Bacilli	S	Phosphoesterase	ykuE	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
WH3_k127_9782334_0	309807.SRU_1584	1.718e-05	57.0	COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,1FJ24@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
WH3_k127_979441_2	756272.Plabr_1647	1.316e-11	72.0	COG2804@1|root,COG2804@2|Bacteria,2IXVD@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE
WH3_k127_979441_0	1123508.JH636444_gene5181	7.813e-106	356.0	COG2805@1|root,COG2805@2|Bacteria,2IX6Y@203682|Planctomycetes	203682|Planctomycetes	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WH3_k127_979441_3	391616.OA238_c46700	4.944e-07	52.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria	1224|Proteobacteria	L	IS30 family	ISPlu1B	-	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
WH3_k127_979441_1	595460.RRSWK_04104	2.888e-21	96.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
WH3_k127_9800898_1	269797.Mbar_A2751	4.955e-35	140.0	arCOG02527@1|root,arCOG02527@2157|Archaea,2Y6XK@28890|Euryarchaeota,2NAMP@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9800898_0	215803.DB30_6663	7.372e-43	160.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WJEW@28221|Deltaproteobacteria,2YTWM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	capL	-	1.1.1.136,1.1.1.336	ko:K02472,ko:K02474,ko:K13015	ko00520,ko05111,map00520,map05111	-	R00421,R03317,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WH3_k127_9815208_0	1173025.GEI7407_1634	1.113e-118	389.0	COG2189@1|root,COG2189@2|Bacteria,1G2XK@1117|Cyanobacteria,1HA14@1150|Oscillatoriales	1117|Cyanobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
WH3_k127_9815208_1	1121382.JQKG01000023_gene1514	3.436e-44	164.0	COG0066@1|root,COG0066@2|Bacteria,1WIV4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
WH3_k127_9817122_0	1304880.JAGB01000001_gene463	4.559e-140	458.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	rhaB	-	2.7.1.5,2.7.1.51	ko:K00848,ko:K00879	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014,R03241	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
WH3_k127_9821627_0	941824.TCEL_01994	9.687e-140	452.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,36EZX@31979|Clostridiaceae	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
WH3_k127_9835808_0	933262.AXAM01000042_gene1835	5.065e-180	574.0	COG1032@1|root,COG1032@2|Bacteria,1NRWP@1224|Proteobacteria,42S72@68525|delta/epsilon subdivisions,2WNA6@28221|Deltaproteobacteria,2MKAP@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
WH3_k127_9835808_1	933262.AXAM01000049_gene3264	1.497e-121	407.0	COG0859@1|root,COG0859@2|Bacteria,1P0ST@1224|Proteobacteria	1224|Proteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9835808_2	933262.AXAM01000049_gene3265	9.172e-12	66.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria,2MIGM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM lipopolysaccharide heptosyltransferase II	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WH3_k127_9842326_2	485913.Krac_4867	4.848e-06	55.0	COG1670@1|root,COG1670@2|Bacteria,2G8V1@200795|Chloroflexi	2|Bacteria	J	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3,GNAT_acetyltran
WH3_k127_9842326_0	985053.VMUT_1131	1.273e-66	246.0	COG1032@1|root,arCOG01356@2157|Archaea,2XQ4W@28889|Crenarchaeota	28889|Crenarchaeota	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
WH3_k127_9842326_1	945713.IALB_2483	1.759e-23	107.0	2ART5@1|root,31H4G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9853020_0	1297570.MESS4_670033	0.0	1162.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2TTXG@28211|Alphaproteobacteria,43K0Q@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
WH3_k127_9853020_2	1037409.BJ6T_21760	1.21e-58	212.0	2C2X7@1|root,31WBU@2|Bacteria,1P2EC@1224|Proteobacteria,2UV16@28211|Alphaproteobacteria,3JWR5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF4239)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
WH3_k127_9853020_1	909663.KI867149_gene3179	6.137e-98	323.0	COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,42PD2@68525|delta/epsilon subdivisions,2WJIK@28221|Deltaproteobacteria,2MR97@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SEC-C,SPASM
WH3_k127_9871347_2	927677.ALVU02000001_gene1339	8.662e-15	78.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1G1DF@1117|Cyanobacteria,1H58Q@1142|Synechocystis	1117|Cyanobacteria	F	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
WH3_k127_9871347_0	1049564.TevJSym_bb00240	1.326e-174	561.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1J4PB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
WH3_k127_9871347_1	880073.Calab_2882	3.398e-93	312.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,2NP08@2323|unclassified Bacteria	2|Bacteria	E	Glutamate synthase central domain	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
WH3_k127_987203_1	349161.Dred_0608	3.081e-55	202.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia,264VH@186807|Peptococcaceae	186801|Clostridia	C	pyridine nucleotide-disulphide oxidoreductase dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
WH3_k127_987203_0	1035308.AQYY01000001_gene1729	1.189e-57	212.0	2DV20@1|root,33TMX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9883624_0	555088.DealDRAFT_1805	4.059e-26	115.0	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH3_k127_9883624_1	889378.Spiaf_0259	0.0002282	50.0	COG1216@1|root,COG1216@2|Bacteria,2J8ZQ@203691|Spirochaetes	203691|Spirochaetes	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WH3_k127_9892006_1	363253.LI0331	2.71e-25	106.0	COG1449@1|root,COG1449@2|Bacteria,1R8JX@1224|Proteobacteria,42QA5@68525|delta/epsilon subdivisions,2WMM5@28221|Deltaproteobacteria,2M9GJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
WH3_k127_9892006_0	945713.IALB_1958	1.862e-56	211.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	glgX	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
WH3_k127_9893215_0	375286.mma_0138	8.37e-27	114.0	COG3296@1|root,COG3296@2|Bacteria,1N4ZK@1224|Proteobacteria,2VWRG@28216|Betaproteobacteria,477FS@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
WH3_k127_989417_2	583355.Caka_1748	2.064e-20	101.0	COG0265@1|root,COG0265@2|Bacteria,46SZ1@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
WH3_k127_989417_1	1449126.JQKL01000038_gene971	2.212e-59	217.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,2688N@186813|unclassified Clostridiales	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
WH3_k127_989417_0	794903.OPIT5_01650	7.21e-77	271.0	COG0857@1|root,COG0857@2|Bacteria,46UEZ@74201|Verrucomicrobia,3K761@414999|Opitutae	414999|Opitutae	C	AAA domain	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
WH3_k127_989817_0	530564.Psta_2342	6.28e-88	308.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2IWX4@203682|Planctomycetes	203682|Planctomycetes	C	PFAM FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
WH3_k127_9900794_5	880073.Calab_0420	5.036e-05	45.0	COG3259@1|root,COG3259@2|Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	hoxH	-	1.12.1.2,1.8.98.5	ko:K00436,ko:K14126	ko00680,map00680	-	R00019,R00700,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
WH3_k127_9900794_1	237368.SCABRO_02488	1.947e-84	288.0	COG1941@1|root,COG1941@2|Bacteria,2IXWB@203682|Planctomycetes	203682|Planctomycetes	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
WH3_k127_9900794_0	880073.Calab_0418	2.627e-89	302.0	COG0543@1|root,COG0543@2|Bacteria,2NPFH@2323|unclassified Bacteria	2|Bacteria	CH	Oxidoreductase NAD-binding domain	asrB	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K02823,ko:K16951	ko00240,ko00920,ko01100,ko01120,map00240,map00920,map01100,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS12555	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
WH3_k127_9900794_2	552811.Dehly_0927	1.01e-73	260.0	COG0543@1|root,COG2204@1|root,COG0543@2|Bacteria,COG2204@2|Bacteria,2G7HU@200795|Chloroflexi	200795|Chloroflexi	C	Oxidoreductase NAD-binding domain	-	-	1.18.1.3	ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,map00623,map00920,map01100,map01120,map01220	M00538	R02550,R03562,R05666,R09513	RC00269,RC00490,RC02556	ko00000,ko00001,ko00002,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
WH3_k127_9900794_3	1121272.KB903250_gene3098	2.413e-45	171.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,4D9TJ@85008|Micromonosporales	201174|Actinobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
WH3_k127_9900794_4	237368.SCABRO_02486	5.333e-27	116.0	COG0680@1|root,COG0680@2|Bacteria,2J190@203682|Planctomycetes	203682|Planctomycetes	C	Hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	HycI
WH3_k127_9903796_1	1229520.ADIAL_0366	7.923e-06	49.0	COG1394@1|root,COG1394@2|Bacteria,1TQ1Y@1239|Firmicutes,4HC4A@91061|Bacilli,27FCW@186828|Carnobacteriaceae	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	ntpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
WH3_k127_9903796_0	525903.Taci_0859	1.373e-174	552.0	COG1156@1|root,COG1156@2|Bacteria,3TA1B@508458|Synergistetes	508458|Synergistetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
WH3_k127_9904100_0	1000565.METUNv1_03770	1.369e-34	145.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,2VUX2@28216|Betaproteobacteria	28216|Betaproteobacteria	M	glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_transf_7C,Glycos_transf_2,PIG-L
WH3_k127_9904100_1	1142394.PSMK_24590	1.047e-28	130.0	COG0265@1|root,COG0750@1|root,COG0265@2|Bacteria,COG0750@2|Bacteria,2IXWE@203682|Planctomycetes	203682|Planctomycetes	M	PDZ domain (Also known as DHR	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
WH3_k127_9908288_0	1262914.BN533_01411	1.09e-167	547.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H236@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
WH3_k127_9908288_1	314230.DSM3645_22886	4.332e-68	241.0	COG0142@1|root,COG0142@2|Bacteria,2IX56@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
WH3_k127_9908288_2	1120985.AUMI01000001_gene2109	1.969e-33	136.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,4H2R1@909932|Negativicutes	909932|Negativicutes	EH	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction	dat	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
WH3_k127_9912455_3	502025.Hoch_5959	1.323e-43	163.0	COG5421@1|root,COG5421@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2
WH3_k127_9912455_1	56780.SYN_02504	1.142e-149	483.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,42P7C@68525|delta/epsilon subdivisions,2WKKF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM MltA domain protein	-	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
WH3_k127_9912455_0	237368.SCABRO_00441	5.058e-171	548.0	COG1236@1|root,COG1236@2|Bacteria,2IXNS@203682|Planctomycetes	203682|Planctomycetes	J	Exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
WH3_k127_9912455_4	498761.HM1_1963	5.113e-39	154.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia	186801|Clostridia	H	Siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
WH3_k127_9912455_2	1125863.JAFN01000001_gene1785	1.223e-59	212.0	COG1838@1|root,COG1838@2|Bacteria,1RCSV@1224|Proteobacteria,42NRW@68525|delta/epsilon subdivisions,2X5RX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit	-	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
WH3_k127_9919336_0	237368.SCABRO_03725	2.174e-93	308.0	COG1697@1|root,COG1697@2|Bacteria,2J34C@203682|Planctomycetes	203682|Planctomycetes	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
WH3_k127_9919336_1	1142394.PSMK_29570	2.735e-58	210.0	COG0325@1|root,COG0325@2|Bacteria,2IZ9R@203682|Planctomycetes	203682|Planctomycetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
WH3_k127_9925036_0	756272.Plabr_2812	1.147e-14	87.0	COG1792@1|root,COG1792@2|Bacteria,2J54G@203682|Planctomycetes	203682|Planctomycetes	M	Involved in formation and maintenance of cell shape	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9928148_3	557598.LHK_00559	1.655e-08	66.0	COG4191@1|root,COG4191@2|Bacteria,1QUWB@1224|Proteobacteria,2VKT0@28216|Betaproteobacteria,2KQY0@206351|Neisseriales	206351|Neisseriales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_8
WH3_k127_9928148_1	237368.SCABRO_04014	8.55e-14	74.0	COG1826@1|root,COG1826@2|Bacteria,2J1B7@203682|Planctomycetes	203682|Planctomycetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
WH3_k127_9928148_0	313628.LNTAR_21460	5.444e-35	142.0	COG3250@1|root,COG5434@1|root,COG3250@2|Bacteria,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	3.2.1.51,4.2.2.23	ko:K01206,ko:K18197	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29,PL11	-	Beta_helix,DUF1565,F5_F8_type_C,Pectate_lyase_3
WH3_k127_9928148_2	1123070.KB899262_gene1714	7.725e-11	64.0	COG0412@1|root,COG0657@1|root,COG0412@2|Bacteria,COG0657@2|Bacteria,46UP5@74201|Verrucomicrobia,2IVN6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
WH3_k127_9928813_0	1118059.CAHC01000012_gene340	1.947e-75	266.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,3WCCY@538999|Clostridiales incertae sedis	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
WH3_k127_9928813_1	1123373.ATXI01000023_gene1785	1.328e-10	64.0	COG0438@1|root,COG0438@2|Bacteria,2GHK9@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9930069_1	195103.CPF_2113	1.505e-13	78.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,36EE6@31979|Clostridiaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
WH3_k127_9930069_0	871968.DESME_15600	2.825e-76	265.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,260W1@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
WH3_k127_9931424_0	1303518.CCALI_01287	4.834e-219	686.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00162,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
WH3_k127_9940484_3	449447.MAE_58220	5.265e-05	51.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG2912 conserved	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
WH3_k127_9940484_2	1282362.AEAC466_07600	3.531e-06	54.0	COG1872@1|root,COG1872@2|Bacteria,1N6V2@1224|Proteobacteria,2UF67@28211|Alphaproteobacteria,2KH69@204458|Caulobacterales	204458|Caulobacterales	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
WH3_k127_9940484_0	56780.SYN_02850	1.098e-95	324.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,2MQCF@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
WH3_k127_9940484_1	243231.GSU1756	6.938e-46	177.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria,43U15@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
WH3_k127_9958977_0	1236973.JCM9157_2913	3.038e-05	51.0	COG3266@1|root,COG3266@2|Bacteria,1VDA3@1239|Firmicutes,4ITGR@91061|Bacilli,1ZDHT@1386|Bacillus	91061|Bacilli	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,TPR_19
WH3_k127_9970104_0	1121324.CLIT_20c00470	9.384e-37	145.0	COG2109@1|root,COG2109@2|Bacteria,1V70U@1239|Firmicutes,24JNB@186801|Clostridia,25TZ8@186804|Peptostreptococcaceae	186801|Clostridia	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	cobO	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
WH3_k127_9970104_1	326427.Cagg_2299	8.304e-06	54.0	2EGCD@1|root,33A46@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF4190
WH3_k127_9975762_1	1223543.GP2_030_00010	6.92e-47	170.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,4GCY8@85026|Gordoniaceae	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WH3_k127_9975762_0	93220.LV28_13490	1.75e-115	380.0	COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,2VM05@28216|Betaproteobacteria,1K2YR@119060|Burkholderiaceae	28216|Betaproteobacteria	M	glycosyl transferase	wcaI	-	-	ko:K03208	-	-	-	-	ko00000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
## 1912 queries scanned
## Total time (seconds): 11.291931867599487
## Rate: 169.32 q/s